# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Aa_trans PF01490.18 GAX09209.1 - 1.3e-07 30.7 21.9 2.9e-06 26.3 21.9 2.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PalH PF08733.10 GAX09209.1 - 0.37 9.8 8.1 0.064 12.3 3.8 1.9 2 0 0 2 2 2 0 PalH/RIM21 DUF2040 PF09745.9 GAX09210.1 - 8.8e-28 96.8 21.3 1.8e-27 95.8 21.3 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) EF-1_beta_acid PF10587.9 GAX09211.1 - 0.54 10.8 0.1 0.54 10.8 0.1 3.5 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region PQQ_2 PF13360.6 GAX09212.1 - 6.4e-13 48.8 1.5 2.3e-06 27.4 0.1 2.6 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 GAX09212.1 - 9.8e-08 32.3 8.4 0.0063 17.0 0.1 5.5 6 0 0 6 6 6 2 PQQ-like domain CYSTM PF12734.7 GAX09212.1 - 0.081 13.3 0.1 0.081 13.3 0.1 3.0 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance PQQ PF01011.21 GAX09212.1 - 0.17 11.9 2.8 0.73 9.9 0.0 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat MatP PF06303.12 GAX09213.1 - 0.055 14.0 0.5 0.32 11.6 0.1 2.2 2 0 0 2 2 2 0 MatP N-terminal domain SOUL PF04832.12 GAX09214.1 - 7.1e-42 143.4 0.1 1.2e-39 136.2 0.1 2.0 1 1 0 1 1 1 1 SOUL heme-binding protein Actin PF00022.19 GAX09216.1 - 1.4e-59 201.8 0.0 2.2e-59 201.1 0.0 1.3 1 1 0 1 1 1 1 Actin Actin PF00022.19 GAX09217.1 - 3.2e-24 85.3 0.0 3.4e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Actin Ribosomal_L30 PF00327.20 GAX09219.1 - 3.2e-07 30.1 0.1 6.1e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 GAX09219.1 - 0.014 15.6 2.7 0.014 15.6 2.7 1.8 1 1 0 1 1 1 0 Ribosomal L30 N-terminal domain YL1 PF05764.13 GAX09220.1 - 8.1 6.5 29.4 21 5.1 29.4 1.6 1 1 0 1 1 1 0 YL1 nuclear protein Aa_trans PF01490.18 GAX09221.1 - 1.8e-35 122.4 21.1 2.3e-35 122.1 21.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 GAX09222.1 - 2.6e-32 112.0 23.9 3.2e-32 111.8 23.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mob1_phocein PF03637.17 GAX09223.1 - 4.1e-47 160.3 0.0 4.8e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Ank_2 PF12796.7 GAX09224.1 - 1.5e-96 317.1 15.5 8.2e-16 58.4 0.0 8.7 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX09224.1 - 7e-78 256.1 3.9 2.2e-09 37.7 0.0 12.9 7 3 6 14 14 14 14 Ankyrin repeats (many copies) Ank PF00023.30 GAX09224.1 - 4.6e-67 219.7 9.8 3e-05 24.3 0.0 18.0 17 2 0 17 17 17 14 Ankyrin repeat Ank_5 PF13857.6 GAX09224.1 - 7.3e-66 217.4 17.3 1.3e-08 34.9 0.0 13.4 8 3 6 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX09224.1 - 7e-60 191.9 3.7 0.00041 20.6 0.0 18.1 19 0 0 19 19 19 13 Ankyrin repeat Arg_repressor PF01316.21 GAX09224.1 - 0.18 11.6 0.2 2.7 7.8 0.0 3.0 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain Sulfotransfer_2 PF03567.14 GAX09225.1 - 1.1e-25 91.1 0.0 1.5e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family LRAT PF04970.13 GAX09226.1 - 0.00049 20.4 1.0 0.0033 17.7 1.0 2.2 1 1 0 1 1 1 1 Lecithin retinol acyltransferase IQ PF00612.27 GAX09226.1 - 0.11 12.3 2.1 0.36 10.7 2.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif PrsW-protease PF13367.6 GAX09227.1 - 0.0004 19.9 0.8 0.0004 19.9 0.8 3.1 4 0 0 4 4 4 2 PrsW family intramembrane metalloprotease DUF2207 PF09972.9 GAX09227.1 - 2.1 7.0 6.7 12 4.5 0.0 4.1 3 2 0 4 4 4 0 Predicted membrane protein (DUF2207) AA_permease_C PF13906.6 GAX09227.1 - 7.3 6.7 7.8 0.69 10.0 2.3 2.1 2 0 0 2 2 2 0 C-terminus of AA_permease KH_1 PF00013.29 GAX09228.1 - 3.5e-29 100.4 0.1 5.6e-14 51.7 0.0 2.7 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 GAX09228.1 - 0.001 18.9 0.0 0.16 11.8 0.1 2.5 2 0 0 2 2 2 1 KH domain PRP9_N PF16958.5 GAX09228.1 - 0.0049 16.9 3.0 0.011 15.8 3.0 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor PRP9 N-terminus KH_4 PF13083.6 GAX09228.1 - 0.033 14.1 0.1 6.5 6.7 0.0 2.8 3 0 0 3 3 3 0 KH domain Raf1_HTH PF18579.1 GAX09228.1 - 0.034 13.8 0.2 0.082 12.6 0.2 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain GLTSCR1 PF15249.6 GAX09228.1 - 0.064 13.7 4.1 0.13 12.7 1.2 2.4 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein FmdA_AmdA PF03069.15 GAX09229.1 - 2.9e-169 562.8 0.0 3.4e-169 562.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Sulfotransfer_2 PF03567.14 GAX09230.1 - 2.1e-23 83.5 0.2 2.7e-23 83.2 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family Nif11 PF07862.11 GAX09230.1 - 0.19 12.1 3.2 28 5.1 0.7 3.4 3 1 0 3 3 3 0 Nif11 domain AA_kinase PF00696.28 GAX09231.1 - 3.2e-35 121.9 0.0 1.1e-34 120.2 0.0 1.9 1 1 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 GAX09231.1 - 1.1e-31 110.1 0.6 8.6e-30 103.9 0.0 3.0 2 1 0 2 2 2 1 Homoserine dehydrogenase ACT_7 PF13840.6 GAX09231.1 - 1.9e-11 43.6 3.3 8.7e-07 28.6 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 GAX09231.1 - 1.9e-10 40.3 2.8 7.5e-06 25.6 0.1 3.1 2 0 0 2 2 2 2 ACT domain NAD_binding_3 PF03447.16 GAX09231.1 - 4.9e-08 33.6 0.0 3.6e-07 30.8 0.0 2.6 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_6 PF13740.6 GAX09231.1 - 0.0022 17.9 3.0 1.4 8.9 0.1 4.2 4 0 0 4 4 4 1 ACT domain S-methyl_trans PF02574.16 GAX09231.1 - 0.0041 17.0 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 Homocysteine S-methyltransferase TPP1 PF10341.9 GAX09232.1 - 0.064 13.2 0.2 6.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Shelterin complex subunit, TPP1/ACD Mito_carr PF00153.27 GAX09234.1 - 1.5e-37 127.4 4.1 3.3e-16 59.0 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Cpn60_TCP1 PF00118.24 GAX09235.1 - 1.4e-136 456.0 3.0 1.7e-136 455.8 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DEAD PF00270.29 GAX09236.1 - 4.7e-39 134.0 0.0 4.4e-38 130.8 0.0 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX09236.1 - 3.6e-25 88.5 0.2 4.5e-23 81.7 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAX09236.1 - 4.4e-12 46.1 0.0 1.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAX09236.1 - 2.3e-08 34.2 0.0 5.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX09236.1 - 0.045 13.0 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_11 PF13086.6 GAX09236.1 - 1.6 8.5 0.0 1.6 8.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF285 PF03382.14 GAX09237.1 - 1.9e-146 479.6 60.1 1.4e-31 108.7 8.0 6.3 3 2 3 6 6 6 6 Mycoplasma protein of unknown function, DUF285 zf-C2HC5 PF06221.13 GAX09237.1 - 5.3 7.1 8.7 0.82 9.7 1.5 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Tic110 PF16940.5 GAX09238.1 - 5.4e-16 58.2 12.2 8.6e-07 27.8 0.2 4.1 3 1 1 4 4 4 3 Chloroplast envelope transporter Phage_TAC_3 PF06896.11 GAX09238.1 - 0.19 12.3 0.1 0.19 12.3 0.1 3.7 4 0 0 4 4 4 0 Phage tail assembly chaperone proteins, TAC LcrG PF07216.12 GAX09238.1 - 1.6 8.7 8.1 8.3 6.4 0.2 3.9 3 0 0 3 3 3 0 LcrG protein Enolase_C PF00113.22 GAX09239.1 - 2.2e-132 440.8 0.0 2.8e-132 440.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAX09239.1 - 5.1e-58 194.9 0.2 9.7e-58 194.0 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAX09239.1 - 9.2e-09 35.2 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAX09239.1 - 3.3e-05 23.2 0.1 3.3e-05 23.2 0.1 2.0 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus ABC_tran PF00005.27 GAX09240.1 - 1.7e-50 171.1 5.3 2e-25 89.9 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX09240.1 - 3.6e-19 68.6 5.9 2.1e-18 66.1 1.7 5.9 6 0 0 6 6 5 2 ABC transporter AAA_21 PF13304.6 GAX09240.1 - 3.2e-12 46.9 7.8 0.0059 16.5 0.1 4.6 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX09240.1 - 2.7e-07 31.1 0.1 0.032 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 GAX09240.1 - 5.8e-07 29.2 13.1 0.0017 17.8 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 GAX09240.1 - 1.4e-06 28.6 6.3 0.033 14.4 0.0 4.1 3 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 GAX09240.1 - 3.9e-06 27.4 0.3 0.28 11.7 0.0 3.8 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 GAX09240.1 - 5.6e-06 26.4 0.0 0.088 12.7 0.0 3.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAX09240.1 - 7e-06 26.4 3.3 0.0029 17.9 0.0 3.9 3 2 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAX09240.1 - 9.7e-06 25.8 0.0 0.057 13.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAX09240.1 - 1.7e-05 24.5 0.1 0.027 14.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_14 PF13173.6 GAX09240.1 - 4.2e-05 23.6 0.2 0.23 11.5 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 GAX09240.1 - 5e-05 23.1 0.0 0.16 11.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 GAX09240.1 - 0.0001 22.7 0.0 0.96 9.9 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GAX09240.1 - 0.00015 21.8 4.5 0.053 13.6 0.0 3.7 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.6 GAX09240.1 - 0.00021 20.9 0.0 0.0094 15.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAX09240.1 - 0.00028 20.5 0.9 1.1 8.9 0.0 3.2 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAX09240.1 - 0.00097 18.9 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX09240.1 - 0.0015 17.8 0.1 0.33 10.2 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 GAX09240.1 - 0.0021 18.0 1.3 0.42 10.5 0.0 3.2 3 1 0 3 3 3 1 NACHT domain Rad17 PF03215.15 GAX09240.1 - 0.0024 17.8 3.0 0.8 9.6 0.0 3.6 4 0 0 4 4 3 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 GAX09240.1 - 0.0055 16.5 0.2 1.6 8.4 0.1 2.5 2 0 0 2 2 2 1 Cytidylate kinase AAA_7 PF12775.7 GAX09240.1 - 0.0058 16.2 0.1 0.28 10.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GAX09240.1 - 0.0072 16.7 0.0 1.5 9.2 0.0 3.0 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 GAX09240.1 - 0.013 15.5 0.1 2.3 8.2 0.0 2.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 GAX09240.1 - 0.026 13.5 0.1 1.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 GAX09240.1 - 0.028 14.2 0.2 4 7.2 0.0 3.2 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 GAX09240.1 - 0.043 14.0 1.9 1.4 9.2 0.0 3.5 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 GAX09240.1 - 0.048 13.3 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 GAX09240.1 - 0.069 13.6 0.1 0.069 13.6 0.1 6.2 5 2 0 5 5 4 0 AAA domain IstB_IS21 PF01695.17 GAX09240.1 - 0.071 12.8 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 GAX09240.1 - 0.094 12.5 0.1 6.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 GAX09240.1 - 0.15 11.7 3.8 0.84 9.2 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 GAX09240.1 - 0.19 11.8 0.0 0.19 11.8 0.0 4.2 4 1 0 4 4 2 0 Dynamin family AAA_15 PF13175.6 GAX09240.1 - 0.24 11.0 0.0 0.24 11.0 0.0 5.0 3 2 0 4 4 4 0 AAA ATPase domain Adaptin_binding PF10199.9 GAX09240.1 - 9.9 6.8 23.4 8.5e+02 0.6 0.1 4.0 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4746 PF15928.5 GAX09241.1 - 0.64 9.4 8.4 1.1 8.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF179 PF02622.15 GAX09242.1 - 2.8e-05 24.1 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 HRI1 PF16815.5 GAX09243.1 - 1.8e-06 27.8 0.0 2.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein HRI1 SPRY PF00622.28 GAX09244.1 - 1.2e-38 131.9 0.8 3.4e-16 59.4 0.1 4.6 4 0 0 4 4 4 3 SPRY domain HECT PF00632.25 GAX09244.1 - 1.4e-37 129.9 0.1 8.7e-34 117.4 0.1 2.3 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) UBA PF00627.31 GAX09244.1 - 3.7e-09 36.3 2.9 1.4e-07 31.3 0.0 3.6 3 0 0 3 3 3 1 UBA/TS-N domain MIB_HERC2 PF06701.13 GAX09244.1 - 0.0046 17.2 3.3 0.026 14.7 3.3 2.3 1 1 0 1 1 1 1 Mib_herc2 Ceramidase PF05875.12 GAX09245.1 - 0.036 13.5 2.5 1.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Ceramidase Per1 PF04080.13 GAX09245.1 - 0.16 11.7 3.4 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Per1-like family DUF3522 PF12036.8 GAX09245.1 - 1.4 9.2 6.5 7.5 6.8 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) DUF1279 PF06916.13 GAX09246.1 - 5.1e-12 46.2 0.3 9.6e-12 45.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) STT3 PF02516.14 GAX09247.1 - 1.5e-52 179.1 25.3 1.2e-30 106.9 8.6 3.1 3 0 0 3 3 3 3 Oligosaccharyl transferase STT3 subunit PDZ PF00595.24 GAX09248.1 - 0.00059 20.1 0.2 0.0015 18.9 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX09248.1 - 0.0012 19.1 0.3 0.0041 17.4 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX09248.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PT PF04886.12 GAX09248.1 - 0.11 12.1 0.3 0.11 12.1 0.3 3.5 2 1 0 2 2 2 0 PT repeat AstE_AspA PF04952.14 GAX09249.1 - 3.8e-31 108.3 0.0 5e-29 101.3 0.0 2.4 2 1 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family EF-hand_5 PF13202.6 GAX09250.1 - 2.7e-07 29.8 3.7 0.028 13.9 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_1 PF00036.32 GAX09250.1 - 1.5e-06 27.3 3.5 0.093 12.3 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GAX09250.1 - 1.8e-05 25.1 0.7 2.1 8.8 0.1 3.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 GAX09250.1 - 0.00026 20.8 0.1 0.065 13.1 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX09250.1 - 0.0011 18.7 2.1 2.7 8.2 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain VCBS PF13517.6 GAX09250.1 - 0.27 11.9 1.2 28 5.4 0.2 3.4 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HSP70 PF00012.20 GAX09251.1 - 8.9e-94 314.8 0.9 3.7e-93 312.7 0.1 2.2 2 1 0 2 2 2 1 Hsp70 protein SPARC_Ca_bdg PF10591.9 GAX09251.1 - 0.049 13.9 0.2 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region p450 PF00067.22 GAX09252.1 - 9.8e-65 219.1 0.0 1.3e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hyr1 PF15789.5 GAX09252.1 - 0.066 12.8 0.7 0.17 11.5 0.7 1.6 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 His_Phos_1 PF00300.22 GAX09253.1 - 6.6e-35 120.6 0.0 1.2e-28 100.2 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tim17 PF02466.19 GAX09254.1 - 6.5e-05 23.3 0.0 0.00044 20.6 0.0 2.3 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF3938 PF13074.6 GAX09254.1 - 0.12 12.7 0.6 0.35 11.1 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) NatB_MDM20 PF09797.9 GAX09255.1 - 3e-39 135.0 0.0 5.9e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit NARP1 PF12569.8 GAX09255.1 - 3.8e-06 26.1 0.2 9.5e-06 24.8 0.0 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 GAX09255.1 - 0.0016 19.1 0.2 0.018 15.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX09255.1 - 0.0086 16.1 2.4 0.067 13.3 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX09255.1 - 0.033 14.4 2.3 0.13 12.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX09255.1 - 0.059 13.9 8.5 0.26 11.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX09255.1 - 0.076 13.7 0.0 0.35 11.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat PEP-utilizers_C PF02896.18 GAX09256.1 - 8.4e-77 258.2 0.0 1.2e-76 257.6 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 GAX09256.1 - 8.7e-55 186.3 0.0 4.8e-34 118.1 0.0 3.2 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 GAX09256.1 - 5.4e-25 86.9 1.2 1e-24 86.0 0.2 2.0 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain NitrOD5 PF11537.8 GAX09256.1 - 0.0018 18.4 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 2 Nitrosopumilus output domain 5 PerC PF06069.11 GAX09256.1 - 0.017 15.4 0.0 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 PerC transcriptional activator IBB PF01749.20 GAX09257.1 - 3.9e-05 24.0 2.6 3.9e-05 24.0 2.6 1.8 2 0 0 2 2 2 1 Importin beta binding domain V-ATPase_H_N PF03224.14 GAX09257.1 - 0.059 12.7 0.9 0.38 10.0 0.2 2.6 2 1 0 2 2 2 0 V-ATPase subunit H SH2_2 PF14633.6 GAX09258.1 - 2.2e-53 180.9 0.0 5e-53 179.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 GAX09258.1 - 1.5e-19 70.3 0.0 3.3e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 GAX09258.1 - 1.8e-12 47.7 3.0 2.9e-12 47.0 1.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 GAX09258.1 - 2.5e-10 40.3 0.0 4.8e-09 36.2 0.0 2.5 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 S1 PF00575.23 GAX09258.1 - 3.1e-10 40.3 0.5 6.6e-10 39.2 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 GAX09258.1 - 4.2e-05 23.7 0.0 9.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2 PF00017.24 GAX09258.1 - 0.027 14.6 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 SH2 domain PsiA PF06952.11 GAX09258.1 - 0.03 13.6 1.6 0.07 12.4 1.6 1.6 1 0 0 1 1 1 0 PsiA protein Tex_YqgF PF16921.5 GAX09258.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Tex protein YqgF-like domain Ion_trans_2 PF07885.16 GAX09260.1 - 5.6e-17 61.5 14.3 9.1e-09 35.2 2.9 2.6 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 GAX09260.1 - 0.0021 17.3 11.0 0.065 12.4 1.3 2.4 2 0 0 2 2 2 2 Ion transport protein PP2C PF00481.21 GAX09261.1 - 6.9e-35 120.9 0.0 1.7e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C cNMP_binding PF00027.29 GAX09261.1 - 1.9e-30 104.8 0.0 4.5e-16 58.7 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain SpoIIE PF07228.12 GAX09261.1 - 4e-06 26.9 0.1 0.00099 19.1 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) CoA_binding_2 PF13380.6 GAX09262.1 - 2.1e-38 131.4 0.1 2.6e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 GAX09262.1 - 3.1e-08 34.2 0.1 4.9e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 CoA binding domain DeoC PF01791.9 GAX09262.1 - 0.02 14.5 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase LRR_8 PF13855.6 GAX09263.1 - 2.2e-22 78.5 31.6 7.7e-08 32.0 3.7 5.4 3 2 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GAX09263.1 - 8.3e-22 76.9 27.8 0.0002 21.6 1.3 6.6 6 0 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX09263.1 - 9.4e-06 25.5 26.6 8.2 7.4 0.1 10.9 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX09263.1 - 2.8 8.2 28.8 36 4.8 0.2 8.4 9 0 0 9 9 9 0 Leucine Rich repeat RCC_reductase PF06405.11 GAX09264.1 - 0.0022 17.2 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) VDE PF07137.11 GAX09265.1 - 1.6e-78 263.5 0.2 2e-78 263.2 0.2 1.1 1 0 0 1 1 1 1 VDE lipocalin domain WD40 PF00400.32 GAX09266.1 - 3.7e-21 75.0 10.2 0.00012 22.8 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX09266.1 - 1.9e-13 50.5 3.8 0.022 15.0 0.1 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX09266.1 - 0.00021 21.2 0.1 0.043 13.7 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAX09266.1 - 0.0023 17.0 0.1 0.0078 15.2 0.0 2.0 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 GAX09266.1 - 0.005 16.2 0.1 0.76 9.0 0.1 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus PALB2_WD40 PF16756.5 GAX09266.1 - 0.026 13.4 3.3 0.16 10.8 0.2 2.4 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain E1_dh PF00676.20 GAX09267.1 - 9.8e-16 57.6 0.0 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 GAX09267.1 - 6.8e-12 45.4 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Pkinase PF00069.25 GAX09268.1 - 4.8e-59 199.9 0.0 7.9e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09268.1 - 1.8e-27 96.3 0.0 2.8e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 GAX09268.1 - 2.8e-07 30.8 0.1 0.012 15.9 0.0 2.7 2 1 0 2 2 2 2 Regulator of G protein signaling domain Kinase-like PF14531.6 GAX09268.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Aminotran_1_2 PF00155.21 GAX09269.1 - 5.4e-37 127.8 0.0 6.2e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX09269.1 - 4.6e-05 22.1 0.0 6.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAX09269.1 - 0.0019 17.3 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAX09269.1 - 0.0052 16.1 0.1 0.054 12.8 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAX09269.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Glyoxalase PF00903.25 GAX09270.1 - 4.9e-39 133.4 1.9 1.6e-21 76.8 0.2 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAX09270.1 - 9.2e-13 48.4 0.0 6.4e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAX09270.1 - 0.00049 20.9 0.0 0.019 15.7 0.0 2.8 2 2 0 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.6 GAX09270.1 - 0.03 14.4 0.0 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal Sulfotransfer_1 PF00685.27 GAX09271.1 - 0.0045 16.5 1.5 0.0097 15.4 0.4 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Pkinase PF00069.25 GAX09272.1 - 8.4e-37 127.0 0.0 2.2e-35 122.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09272.1 - 2.2e-20 73.0 0.0 7.7e-20 71.3 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX09272.1 - 3.4e-05 23.3 0.0 6.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAX09272.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AvrRpt-cleavage PF05627.11 GAX09272.1 - 0.039 13.3 0.4 0.098 12.0 0.4 1.6 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr DUF3007 PF11460.8 GAX09273.1 - 3e-29 101.1 0.1 8.3e-29 99.7 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3007) SieB PF14163.6 GAX09273.1 - 0.0052 16.3 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Super-infection exclusion protein B TPK_catalytic PF04263.16 GAX09274.1 - 1.4e-15 57.4 0.0 3.8e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 GAX09274.1 - 1.6e-07 30.9 0.0 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CSN8_PSD8_EIF3K PF10075.9 GAX09275.1 - 3.9e-18 65.8 0.5 3.1e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Tubulin PF00091.25 GAX09276.1 - 2.3e-51 174.8 0.0 3.5e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAX09276.1 - 6.4e-50 168.5 0.0 9.4e-50 168.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAX09276.1 - 0.0053 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Phage_TTP_1 PF04630.12 GAX09277.1 - 0.009 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Phage tail tube protein PI3K_p85B PF02192.16 GAX09277.1 - 0.11 12.3 0.1 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Ras PF00071.22 GAX09278.1 - 2.6e-67 225.4 0.8 3.3e-67 225.1 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX09278.1 - 1.1e-36 125.6 1.2 1.8e-36 124.9 0.1 1.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX09278.1 - 1.2e-17 63.9 0.6 2.4e-17 63.0 0.2 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAX09278.1 - 5.9e-06 26.3 0.5 0.11 12.4 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAX09278.1 - 9.4e-06 25.2 0.2 1.7e-05 24.3 0.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX09278.1 - 1.1e-05 25.4 0.1 7.4e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX09278.1 - 3.2e-05 23.4 0.1 3.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX09278.1 - 0.00012 21.7 0.3 0.00028 20.5 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 GAX09278.1 - 0.0012 18.3 0.2 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 GAX09278.1 - 0.0065 16.2 0.1 0.1 12.4 0.0 2.2 1 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 GAX09278.1 - 0.0082 15.7 0.0 0.029 13.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAX09278.1 - 0.017 15.5 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAX09278.1 - 0.031 14.5 0.1 0.065 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GAX09278.1 - 0.032 14.6 0.1 0.47 10.9 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GAX09278.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 GAX09278.1 - 0.058 13.4 0.0 0.095 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3873 PF12989.7 GAX09278.1 - 0.062 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) DUF3533 PF12051.8 GAX09278.1 - 0.094 11.6 2.3 0.12 11.3 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) ABC_tran PF00005.27 GAX09278.1 - 0.097 13.2 0.1 0.17 12.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 GAX09278.1 - 0.099 12.0 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein ETC_C1_NDUFA4 PF04800.12 GAX09279.1 - 2.8e-18 65.9 1.1 4.8e-18 65.2 1.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region MRP-S24 PF14955.6 GAX09279.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 ThiF PF00899.21 GAX09280.1 - 2.1e-13 50.2 0.0 5.1e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 ThiF family Ribosomal_L7Ae PF01248.26 GAX09280.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family bZIP_2 PF07716.15 GAX09281.1 - 5e-08 32.9 5.3 5e-08 32.9 5.3 1.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX09281.1 - 7.5e-08 32.4 6.2 1.6e-07 31.3 6.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 GAX09281.1 - 0.0012 19.3 2.7 0.0024 18.4 2.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Nucleo_P87 PF07267.11 GAX09281.1 - 0.0084 15.0 1.4 0.0098 14.8 1.4 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 PAS_9 PF13426.7 GAX09282.1 - 3.9e-16 59.2 0.0 9.7e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 GAX09282.1 - 3.6e-08 33.4 10.6 8.2e-08 32.2 10.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX09282.1 - 7.4e-07 29.2 10.2 1.4e-06 28.3 10.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.25 GAX09282.1 - 0.00023 21.2 0.0 0.00048 20.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 GAX09282.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GAX09282.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold bZIP_Maf PF03131.17 GAX09282.1 - 0.26 11.8 8.9 0.22 12.0 7.8 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor CDC45 PF02724.14 GAX09282.1 - 0.32 9.2 5.8 0.4 8.9 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.12 GAX09282.1 - 0.42 9.5 7.1 2.3 7.1 7.6 1.8 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Snf7 PF03357.21 GAX09283.1 - 5.1e-35 120.6 22.7 6.3e-35 120.3 22.7 1.1 1 0 0 1 1 1 1 Snf7 DUF334 PF03904.13 GAX09283.1 - 0.28 10.7 9.8 0.21 11.1 7.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF334) MutS_III PF05192.18 GAX09283.1 - 1.1 9.5 4.4 1.5 9.0 4.4 1.3 1 0 0 1 1 1 0 MutS domain III Glucokinase PF02685.16 GAX09284.1 - 5.6e-71 239.1 0.0 7.2e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Glucokinase HMG_box PF00505.19 GAX09286.1 - 4e-07 30.4 0.8 0.011 16.1 0.0 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX09286.1 - 9.7e-05 22.9 1.0 0.42 11.2 0.0 2.5 2 0 0 2 2 2 2 HMG-box domain Peptidase_M50 PF02163.22 GAX09287.1 - 2.5e-07 30.2 9.8 0.00029 20.2 1.8 3.0 2 1 1 3 3 3 2 Peptidase family M50 PI3_PI4_kinase PF00454.27 GAX09288.1 - 4.7e-45 154.3 0.0 1.2e-44 153.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAX09288.1 - 1.6e-26 93.4 0.0 4.6e-26 91.8 0.0 1.9 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 GAX09288.1 - 5.8e-15 54.8 0.2 1.4e-14 53.5 0.2 1.8 1 0 0 1 1 1 1 FATC domain DUF4135 PF13575.6 GAX09288.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TPR_1 PF00515.28 GAX09288.1 - 0.017 14.9 0.1 0.14 12.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX09288.1 - 0.022 14.8 0.1 0.27 11.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX09288.1 - 0.039 13.6 0.4 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 TPR repeat DUF3385 PF11865.8 GAX09288.1 - 0.4 10.6 6.8 0.76 9.7 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) TPR_12 PF13424.6 GAX09288.1 - 2.9 8.3 4.2 2 8.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SPX PF03105.19 GAX09289.1 - 3e-07 30.7 8.1 3e-07 30.7 8.1 3.0 2 1 0 2 2 2 1 SPX domain FlbD PF06289.11 GAX09289.1 - 0.18 11.4 0.0 0.74 9.5 0.0 1.9 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins N_Asn_amidohyd PF14736.6 GAX09290.1 - 9.9e-57 192.1 0.0 1.3e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase NUDIX PF00293.28 GAX09291.1 - 6.9e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 GAX09292.1 - 7.9e-21 74.6 0.0 2.3e-20 73.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09292.1 - 7.1e-09 35.3 0.0 2.9e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAX09292.1 - 0.0027 17.7 0.0 0.62 9.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family KTI12 PF08433.10 GAX09293.1 - 1.8e-61 208.0 0.8 1.2e-48 165.9 0.1 2.1 1 1 0 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAX09293.1 - 3.1e-07 30.6 0.0 1.4e-06 28.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX09293.1 - 0.00045 20.6 1.2 0.0033 17.8 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX09293.1 - 0.0072 16.6 0.1 0.041 14.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain ZapB PF06005.12 GAX09293.1 - 0.013 15.9 0.1 0.73 10.3 0.0 2.7 2 0 0 2 2 2 0 Cell division protein ZapB AAA_14 PF13173.6 GAX09293.1 - 0.013 15.5 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX09293.1 - 0.016 15.7 0.0 0.038 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PLU-1 PF08429.11 GAX09293.1 - 0.044 13.0 1.7 0.082 12.1 1.1 1.6 1 1 1 2 2 2 0 PLU-1-like protein AAA PF00004.29 GAX09293.1 - 0.046 14.1 0.0 0.34 11.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAX09293.1 - 0.049 12.9 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 GAX09293.1 - 0.07 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein CLP_protease PF00574.23 GAX09294.1 - 2.9e-80 268.5 0.6 3.8e-80 268.1 0.6 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 GAX09294.1 - 0.0042 16.1 0.0 0.0081 15.2 0.0 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Peptidase_M16_M PF16187.5 GAX09295.1 - 3.5e-79 266.0 0.1 6.6e-79 265.1 0.1 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX09295.1 - 3.8e-29 101.6 0.0 1.4e-28 99.8 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX09295.1 - 1.4e-22 80.6 0.0 8.3e-15 55.3 0.0 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain CtIP_N PF10482.9 GAX09296.1 - 0.025 14.6 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain ZapB PF06005.12 GAX09296.1 - 0.044 14.2 0.3 0.079 13.4 0.1 1.5 2 0 0 2 2 2 0 Cell division protein ZapB DUF3658 PF12395.8 GAX09296.1 - 0.094 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function PAP_central PF04928.17 GAX09297.1 - 1.1e-61 207.9 0.0 1.5e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAX09297.1 - 1.9e-17 63.4 0.5 5.3e-15 55.5 0.5 2.3 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAX09297.1 - 0.0004 20.6 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain ICL PF00463.21 GAX09298.1 - 3.1e-216 719.0 0.1 3.5e-216 718.8 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAX09298.1 - 5.9e-11 42.3 0.2 1.1e-10 41.4 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF1336 PF07059.12 GAX09299.1 - 4.8e-49 167.5 0.0 6.2e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) LSM PF01423.22 GAX09300.1 - 1.5e-13 50.2 0.0 2.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain AAA_34 PF13872.6 GAX09300.1 - 0.03 13.2 0.5 0.038 12.9 0.5 1.1 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SM-ATX PF14438.6 GAX09300.1 - 0.22 11.7 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain WD40_alt PF14077.6 GAX09301.1 - 0.019 14.8 0.2 0.036 13.9 0.2 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Ephrin PF00812.17 GAX09302.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Ephrin PP2C PF00481.21 GAX09303.1 - 2e-25 89.9 0.0 2.5e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX09303.1 - 8.4e-05 22.6 0.1 0.00089 19.2 0.1 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAX09303.1 - 0.0013 18.4 0.2 0.014 15.0 0.1 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C DUF1876 PF08962.11 GAX09303.1 - 0.021 14.8 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) Snf7 PF03357.21 GAX09304.1 - 2.1e-36 125.1 19.4 2.8e-36 124.7 19.4 1.1 1 0 0 1 1 1 1 Snf7 ATP_sub_h PF10775.9 GAX09304.1 - 0.092 12.7 1.8 0.14 12.1 0.4 2.0 2 0 0 2 2 2 0 ATP synthase complex subunit h RNA_pol_Rpb1_5 PF04998.17 GAX09304.1 - 0.52 9.7 6.7 0.65 9.4 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SAC3_GANP PF03399.16 GAX09305.1 - 7.3e-30 104.4 0.0 1.1e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family MIT PF04212.18 GAX09306.1 - 0.033 14.3 1.0 0.089 12.9 0.1 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 GAX09306.1 - 0.12 12.7 1.0 3.3 8.1 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX09306.1 - 0.71 9.8 5.3 1 9.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_2 PF00152.20 GAX09308.1 - 6.8e-75 252.0 0.0 1e-74 251.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 GAX09308.1 - 7e-09 35.7 2.7 1.8e-08 34.4 2.7 1.8 1 0 0 1 1 1 1 WHEP-TRS domain tRNA_anti-codon PF01336.25 GAX09308.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX09308.1 - 0.014 14.9 0.4 1.9 7.9 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) DUF3408 PF11888.8 GAX09308.1 - 0.67 10.1 7.4 1.4 9.1 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) TP53IP5 PF15331.6 GAX09308.1 - 1.6 8.9 7.3 2.7 8.1 7.3 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PRTP PF01366.18 GAX09308.1 - 2.3 6.1 8.1 3.4 5.6 8.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF2201_N PF13203.6 GAX09308.1 - 3.3 7.2 10.3 6.2 6.3 10.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain ALMT PF11744.8 GAX09308.1 - 6.3 5.5 6.8 9.2 5.0 6.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PP2C PF00481.21 GAX09309.1 - 6.1e-64 216.1 0.2 4.8e-54 183.7 0.1 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 GAX09309.1 - 2.1e-07 31.0 2.2 1.3e-06 28.5 0.4 2.7 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAX09309.1 - 5.7e-06 26.1 0.0 0.044 13.4 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C DUF1188 PF06690.11 GAX09309.1 - 0.13 11.8 0.9 0.22 11.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) DNA_methylase PF00145.17 GAX09310.1 - 8e-09 35.3 3.3 6.7e-06 25.7 0.0 3.8 3 1 1 4 4 4 3 C-5 cytosine-specific DNA methylase PhyH PF05721.13 GAX09311.1 - 0.00067 20.0 0.2 0.0014 18.9 0.2 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PWWP PF00855.17 GAX09311.1 - 0.00078 19.8 0.2 0.0041 17.5 0.0 2.2 2 0 0 2 2 2 1 PWWP domain Agenet PF05641.12 GAX09311.1 - 0.012 16.0 0.3 0.065 13.7 0.0 2.5 2 0 0 2 2 2 0 Agenet domain DUF4537 PF15057.6 GAX09311.1 - 0.014 15.4 0.0 0.07 13.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4537) Smim3 PF17307.2 GAX09311.1 - 0.17 11.4 0.2 0.4 10.2 0.2 1.6 1 0 0 1 1 1 0 Small integral membrane protein 3 DUF285 PF03382.14 GAX09312.1 - 2.3e-99 327.6 40.2 4.6e-30 103.9 2.6 2.7 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 DUF4939 PF16297.5 GAX09312.1 - 0.11 12.3 0.3 2 8.3 0.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) Prefoldin_2 PF01920.20 GAX09313.1 - 6.3e-21 74.3 10.3 7.4e-21 74.1 10.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Mo25 PF08569.11 GAX09313.1 - 0.0029 17.0 0.7 0.0099 15.3 0.8 1.7 1 1 0 1 1 1 1 Mo25-like CRR7 PF12095.8 GAX09313.1 - 0.013 15.9 1.1 0.12 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 APG6_N PF17675.1 GAX09313.1 - 0.021 15.3 10.8 0.059 13.9 2.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 GAX09313.1 - 0.037 14.1 0.5 0.037 14.1 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RUN PF02759.19 GAX09313.1 - 0.045 13.7 0.3 0.091 12.7 0.1 1.6 1 1 0 2 2 2 0 RUN domain Prefoldin PF02996.17 GAX09313.1 - 0.059 13.3 0.8 0.059 13.3 0.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit RPW8 PF05659.11 GAX09313.1 - 0.071 12.8 1.8 1.2 8.8 0.1 2.2 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FerA PF08165.11 GAX09313.1 - 0.073 13.0 0.4 0.073 13.0 0.4 2.3 2 1 0 2 2 2 0 FerA (NUC095) domain HrpB2 PF09487.10 GAX09313.1 - 0.093 13.2 2.2 0.092 13.2 0.7 1.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) Abi_C PF14355.6 GAX09313.1 - 0.15 12.2 0.2 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 Abortive infection C-terminus FlgN PF05130.12 GAX09313.1 - 0.17 12.4 7.9 0.31 11.5 7.9 1.4 1 1 0 1 1 1 0 FlgN protein Laminin_II PF06009.12 GAX09313.1 - 0.18 11.8 3.9 5 7.1 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II Hrs_helical PF12210.8 GAX09313.1 - 0.25 11.9 7.4 1 9.9 2.1 2.2 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DivIVA PF05103.13 GAX09313.1 - 0.42 10.7 6.4 4.8 7.3 0.5 2.1 2 0 0 2 2 2 0 DivIVA protein BBIP10 PF14777.6 GAX09313.1 - 0.43 10.2 4.4 0.34 10.5 1.7 2.2 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 FUSC PF04632.12 GAX09313.1 - 0.61 8.6 4.2 0.69 8.4 4.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 GAX09313.1 - 0.73 10.2 10.4 0.12 12.7 1.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 GAX09313.1 - 0.86 9.9 2.9 6.5 7.1 0.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) KfrA_N PF11740.8 GAX09313.1 - 1.4 9.6 8.1 1.1 9.9 1.7 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Csm1_N PF18504.1 GAX09313.1 - 3.2 8.2 10.4 0.26 11.7 2.0 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain CENP-H PF05837.12 GAX09313.1 - 3.9 7.9 9.2 4.4 7.7 1.3 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 GAX09313.1 - 6 7.4 14.4 5.9 7.4 3.1 2.2 1 1 0 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 GAX09313.1 - 8.6 6.7 9.2 5 7.4 1.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PRORP PF16953.5 GAX09314.1 - 2.9e-14 53.2 5.1 6.2e-07 29.2 0.1 4.7 3 1 0 3 3 3 2 Protein-only RNase P RNase_Zc3h12a PF11977.8 GAX09314.1 - 5.4e-07 29.5 0.2 8e-05 22.5 0.1 2.6 2 0 0 2 2 2 2 Zc3h12a-like Ribonuclease NYN domain SEO_N PF14576.6 GAX09314.1 - 0.0007 18.9 0.1 0.0057 15.9 0.1 2.2 2 0 0 2 2 2 1 Sieve element occlusion N-terminus CLAG PF03805.13 GAX09314.1 - 0.18 9.4 0.1 0.26 8.8 0.1 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein PRORP PF16953.5 GAX09315.1 - 8.9e-17 61.4 0.3 2.6e-08 33.7 0.0 4.2 3 1 0 3 3 3 3 Protein-only RNase P PPR_long PF17177.4 GAX09315.1 - 0.0047 16.3 0.1 0.031 13.6 0.0 2.1 1 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP MFS_1 PF07690.16 GAX09316.1 - 6.8e-15 54.9 21.1 1.5e-14 53.7 21.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1673 PF07895.11 GAX09316.1 - 1.8 8.2 5.0 21 4.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) SH PF01445.17 GAX09316.1 - 3.7 7.6 6.2 0.59 10.1 0.4 2.7 2 0 0 2 2 2 0 Viral small hydrophobic protein Parvo_NS1 PF01057.17 GAX09317.1 - 0.033 13.3 0.1 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MRP-S22 PF10245.9 GAX09317.1 - 0.033 13.9 2.7 0.041 13.6 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 DUF16 PF01519.16 GAX09317.1 - 0.047 14.2 3.5 0.067 13.7 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Glu-tRNAGln PF02686.15 GAX09317.1 - 1.3 9.4 4.2 1.2 9.4 2.8 1.6 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit CS PF04969.16 GAX09318.1 - 1.8e-10 41.7 0.1 2.8e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 CS domain SGS PF05002.15 GAX09318.1 - 0.0065 16.5 1.6 0.014 15.5 1.6 1.6 1 0 0 1 1 1 1 SGS domain Hc1 PF07432.13 GAX09318.1 - 0.019 15.3 0.8 0.019 15.3 0.8 1.8 2 0 0 2 2 2 0 Histone H1-like protein Hc1 Ank_2 PF12796.7 GAX09319.1 - 1.2e-11 45.0 1.7 3.3e-05 24.4 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX09319.1 - 4.5e-11 42.8 0.8 0.00054 20.2 0.1 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX09319.1 - 3.8e-09 36.0 0.6 0.47 11.2 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 GAX09319.1 - 9.5e-08 32.4 0.1 0.028 15.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX09319.1 - 4.1e-06 27.0 1.5 3.1 8.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Phage_tail_X PF05489.12 GAX09319.1 - 0.0053 16.4 0.2 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 Phage Tail Protein X LnmK_N_HDF PF18238.1 GAX09319.1 - 0.15 11.8 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain HMG_box PF00505.19 GAX09320.1 - 4.2e-09 36.7 0.3 1.6e-05 25.2 0.5 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX09320.1 - 3.2e-05 24.4 0.2 0.00083 19.9 0.4 2.3 2 0 0 2 2 2 1 HMG-box domain rve PF00665.26 GAX09321.1 - 0.00011 22.4 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DnaJ PF00226.31 GAX09322.1 - 1.5e-25 89.1 0.6 3.5e-25 87.9 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Ret2_MD PF18528.1 GAX09322.1 - 0.023 15.1 0.5 0.044 14.2 0.5 1.4 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain HA PF03457.14 GAX09323.1 - 2.7e-82 271.0 36.4 1.2e-20 73.6 0.4 6.2 6 0 0 6 6 6 6 Helicase associated domain UBA PF00627.31 GAX09323.1 - 0.17 11.8 0.2 2.7 8.0 0.1 2.7 2 0 0 2 2 2 0 UBA/TS-N domain SF3a60_bindingd PF12108.8 GAX09323.1 - 0.54 10.2 2.3 16 5.5 0.5 3.1 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain RPE65 PF03055.15 GAX09324.1 - 4.2e-71 240.5 0.0 4.9e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein tRNA_int_endo PF01974.17 GAX09325.1 - 1.3e-20 73.2 0.1 3.1e-20 72.0 0.0 1.6 1 1 1 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain Aldo_ket_red PF00248.21 GAX09326.1 - 1.6e-17 63.6 0.2 2.9e-12 46.4 0.0 2.2 1 1 1 2 2 2 2 Aldo/keto reductase family SSXT PF05030.12 GAX09326.1 - 0.099 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Maf PF02545.14 GAX09327.1 - 1.4e-27 96.6 0.0 1.6e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Phage_int_SAM_1 PF02899.17 GAX09328.1 - 0.21 11.9 4.1 0.27 11.6 0.4 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain CNDH2_C PF16858.5 GAX09328.1 - 3.2 7.5 8.5 0.061 13.2 0.3 2.1 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Peptidase_C1 PF00112.23 GAX09329.1 - 9.4e-40 137.0 2.9 1.7e-39 136.2 2.9 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAX09329.1 - 0.0047 15.7 1.6 0.0076 15.1 1.1 1.5 2 0 0 2 2 2 1 Peptidase C1-like family SSPI PF14098.6 GAX09330.1 - 0.13 12.4 1.0 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Small, acid-soluble spore protein I Peptidase_C1 PF00112.23 GAX09331.1 - 3.4e-39 135.2 3.5 4.7e-39 134.7 3.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAX09331.1 - 0.036 12.8 0.6 0.036 12.8 0.6 1.6 3 0 0 3 3 3 0 Peptidase C1-like family RNA_pol_Rpc4 PF05132.14 GAX09332.1 - 4.5e-16 59.6 0.3 4.5e-16 59.6 0.3 3.5 3 1 0 3 3 3 1 RNA polymerase III RPC4 Macoilin PF09726.9 GAX09332.1 - 1.5 7.3 6.6 2 6.9 6.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF1539 PF07560.11 GAX09333.1 - 0.55 10.3 6.7 11 6.2 0.4 3.6 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) Hydrolase_4 PF12146.8 GAX09335.1 - 1.2e-34 119.7 0.0 3.5e-34 118.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX09335.1 - 1.5e-14 55.2 0.0 2.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX09335.1 - 9.8e-08 31.9 0.0 2.2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX09335.1 - 6e-05 22.6 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAX09335.1 - 0.00077 19.3 0.1 2.3 8.0 0.0 3.2 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 GAX09335.1 - 0.0014 18.3 0.0 0.0037 16.9 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 GAX09335.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1104 PF06518.11 GAX09336.1 - 0.03 14.7 0.2 0.03 14.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) PTPRCAP PF15713.5 GAX09336.1 - 3.1 8.1 12.6 0.12 12.7 4.3 2.6 3 1 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Peptidase_M22 PF00814.25 GAX09337.1 - 1.8e-78 264.0 0.0 2.1e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 GAX09337.1 - 4.8e-05 23.2 0.0 9.9e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus FGGY_C PF02782.16 GAX09337.1 - 0.063 13.0 0.1 6.2 6.5 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain PPR_2 PF13041.6 GAX09339.1 - 4.2e-12 46.1 4.1 0.18 12.0 0.0 7.2 6 2 2 8 8 8 4 PPR repeat family PPR_3 PF13812.6 GAX09339.1 - 1.8e-09 37.5 0.1 0.022 14.8 0.0 6.2 4 3 1 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX09339.1 - 4.9e-05 22.9 0.0 1.3 8.8 0.0 5.3 5 0 0 5 5 5 2 PPR repeat PPR PF01535.20 GAX09339.1 - 0.00011 22.2 8.7 8.2 6.9 0.0 8.5 8 2 0 8 8 8 2 PPR repeat PDZ_6 PF17820.1 GAX09340.1 - 8.5e-10 38.3 0.0 2.3e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX09340.1 - 3.4e-09 36.9 0.0 3.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX09340.1 - 0.00017 21.9 0.0 0.0073 16.6 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PT-HINT PF07591.11 GAX09340.1 - 0.046 14.0 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 Pretoxin HINT domain N2227 PF07942.12 GAX09341.1 - 1.7e-74 250.4 0.0 1.2e-71 241.2 0.0 2.2 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 GAX09341.1 - 1.5e-06 28.1 0.0 4.3e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX09341.1 - 2.7e-05 24.8 0.0 0.00034 21.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX09341.1 - 3.7e-05 24.3 0.0 0.016 15.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GAX09341.1 - 0.083 13.6 0.0 5.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain FG-GAP_2 PF14312.6 GAX09342.1 - 0.48 10.7 19.6 0.66 10.3 0.5 6.4 6 0 0 6 6 6 0 FG-GAP repeat DIOX_N PF14226.6 GAX09343.1 - 2.3e-09 38.1 0.0 4.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAX09343.1 - 1.5e-08 35.0 0.0 4.9e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SCNM1_acidic PF15805.5 GAX09344.1 - 0.29 10.9 2.1 2.6 7.8 0.8 2.5 2 0 0 2 2 2 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 AhpC-TSA_2 PF13911.6 GAX09345.1 - 0.0013 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme ABC_tran PF00005.27 GAX09346.1 - 1e-35 123.3 0.0 4.3e-17 62.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 GAX09346.1 - 1.9e-12 46.8 5.0 4.8e-12 45.5 5.0 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 GAX09346.1 - 8.1e-12 45.6 3.2 0.033 14.0 0.0 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX09346.1 - 1.3e-11 44.4 0.4 0.00022 20.7 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX09346.1 - 5e-07 29.8 0.0 0.0059 16.4 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 GAX09346.1 - 5.1e-07 30.2 0.0 0.0018 18.7 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.27 GAX09346.1 - 1.5e-06 27.7 3.9 1.5e-06 27.7 3.9 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 GAX09346.1 - 1.3e-05 25.6 0.0 0.055 13.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX09346.1 - 3.2e-05 24.2 0.0 0.0094 16.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX09346.1 - 3.5e-05 23.8 1.2 0.0059 16.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 GAX09346.1 - 3.7e-05 23.4 0.2 0.29 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.7 GAX09346.1 - 5.3e-05 23.1 3.0 5.3e-05 23.1 3.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 GAX09346.1 - 5.4e-05 23.2 0.1 0.28 11.1 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_24 PF13479.6 GAX09346.1 - 0.00012 21.9 1.0 0.13 12.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 GAX09346.1 - 0.00017 22.1 7.1 0.00097 19.7 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.22 GAX09346.1 - 0.00037 20.2 1.8 0.084 12.5 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 GAX09346.1 - 0.0007 20.1 0.9 0.053 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 GAX09346.1 - 0.00073 19.6 11.5 0.0017 18.5 11.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 GAX09346.1 - 0.00081 19.4 0.1 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 GAX09346.1 - 0.0016 18.4 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 GAX09346.1 - 0.0016 18.8 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 GAX09346.1 - 0.0018 18.3 0.3 0.093 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_2 PF12797.7 GAX09346.1 - 0.0025 17.8 1.1 0.0025 17.8 1.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 GAX09346.1 - 0.0028 17.8 1.5 0.0028 17.8 1.5 1.9 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAX09346.1 - 0.0035 18.2 6.5 0.013 16.5 0.2 2.7 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_28 PF13521.6 GAX09346.1 - 0.004 17.4 0.2 1.5 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX09346.1 - 0.0044 17.6 0.0 4.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAX09346.1 - 0.006 16.3 2.4 0.37 10.5 0.0 3.1 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 GAX09346.1 - 0.007 16.6 0.1 1.3 9.3 0.0 3.2 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit Fer4_10 PF13237.6 GAX09346.1 - 0.0089 16.1 1.7 0.0089 16.1 1.7 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_33 PF13671.6 GAX09346.1 - 0.011 15.9 0.4 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 GAX09346.1 - 0.013 15.2 0.1 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E AAA_7 PF12775.7 GAX09346.1 - 0.031 13.8 0.3 3 7.3 0.0 3.3 4 0 0 4 4 3 0 P-loop containing dynein motor region NB-ARC PF00931.22 GAX09346.1 - 0.038 13.2 0.1 4.9 6.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Thymidylate_kin PF02223.17 GAX09346.1 - 0.04 13.6 0.1 13 5.4 0.1 2.6 2 0 0 2 2 2 0 Thymidylate kinase Fer4_17 PF13534.6 GAX09346.1 - 0.041 14.4 0.3 0.041 14.4 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 GAX09346.1 - 0.042 13.8 1.4 0.94 9.4 0.0 2.8 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 GAX09346.1 - 0.083 13.0 0.1 19 5.4 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 GAX09346.1 - 0.091 12.8 0.0 13 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_13 PF13166.6 GAX09346.1 - 0.1 11.2 0.2 0.2 10.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAX09346.1 - 0.11 12.8 0.7 0.76 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 GAX09346.1 - 0.14 11.4 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain DUF815 PF05673.13 GAX09346.1 - 0.16 11.1 0.1 7.6 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 GAX09346.1 - 0.17 10.9 0.6 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 GAX09346.1 - 0.2 11.9 1.2 1.6 9.0 0.0 2.6 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Fer4_8 PF13183.6 GAX09346.1 - 2.8 8.4 12.0 0.64 10.5 1.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 GAX09346.1 - 3.6 8.3 16.7 0.49 11.0 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Metallophos_2 PF12850.7 GAX09347.1 - 1.6e-19 70.7 0.1 1.9e-19 70.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GAX09347.1 - 0.00028 21.5 0.0 0.63 10.5 0.2 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PRAI PF00697.22 GAX09348.1 - 0.045 13.5 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase TMP-TENI PF02581.17 GAX09348.1 - 0.16 11.3 0.2 2.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase HPP PF04982.13 GAX09349.1 - 0.26 11.5 4.1 0.17 12.1 1.2 1.9 1 1 1 2 2 2 0 HPP family Aa_trans PF01490.18 GAX09350.1 - 8.4e-46 156.5 21.1 1.2e-45 156.0 21.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LOR PF04525.12 GAX09351.1 - 0.00022 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 LURP-one-related Rad51 PF08423.11 GAX09352.1 - 3.3e-24 85.6 0.2 2.6e-22 79.3 0.2 2.1 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 GAX09352.1 - 1.3e-08 34.7 0.0 8.3e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 GAX09352.1 - 4.7e-07 29.4 0.0 1.9e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 GAX09352.1 - 6.6e-07 29.1 0.4 3.1e-06 26.9 0.4 1.9 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAX09352.1 - 1.1e-05 24.9 1.4 5.4e-05 22.6 0.2 2.5 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain TrwB_AAD_bind PF10412.9 GAX09352.1 - 0.0016 17.4 0.3 0.003 16.5 0.3 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 GAX09352.1 - 0.0045 17.5 0.0 0.011 16.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter PhoH PF02562.16 GAX09352.1 - 0.018 14.5 0.4 0.039 13.4 0.4 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 GAX09352.1 - 0.02 15.0 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX09352.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX09352.1 - 0.069 13.1 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 GAX09352.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea 2HCT PF03390.15 GAX09352.1 - 0.11 11.1 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family COPI_assoc PF08507.10 GAX09353.1 - 0.16 12.0 11.6 0.3 11.1 8.0 2.4 2 1 0 2 2 2 0 COPI associated protein CRAL_TRIO PF00650.20 GAX09354.1 - 1.9e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain SKG6 PF08693.10 GAX09354.1 - 3.1 7.3 5.0 1.5 8.3 1.5 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sec1 PF00995.23 GAX09355.1 - 6.1e-101 339.4 0.0 6.9e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Tox-REase-7 PF15649.6 GAX09355.1 - 0.12 12.6 0.0 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 RNase_HII PF01351.18 GAX09356.1 - 2.5e-28 99.3 0.1 1.2e-27 97.1 0.1 2.0 1 1 0 1 1 1 1 Ribonuclease HII Spt20 PF12090.8 GAX09356.1 - 0.0034 17.0 1.0 0.0055 16.3 1.0 1.2 1 0 0 1 1 1 1 Spt20 family RuBisCO_large PF00016.20 GAX09356.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DBR1 PF05011.13 GAX09358.1 - 5.4e-26 91.7 0.0 1.5e-25 90.2 0.0 1.8 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 GAX09358.1 - 7.4e-05 23.3 0.1 0.0009 19.8 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase GTP1_OBG PF01018.22 GAX09359.1 - 3e-36 124.3 0.5 2e-27 95.7 0.6 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 GAX09359.1 - 9.9e-23 80.4 0.0 3.5e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX09359.1 - 3e-07 30.1 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 GAX09359.1 - 0.00014 21.3 0.0 0.00032 20.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family cobW PF02492.19 GAX09359.1 - 0.082 12.5 0.0 7.8 6.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GAX09359.1 - 0.18 12.3 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KIND PF16474.5 GAX09359.1 - 1.6 8.6 4.5 3.4 7.5 4.5 1.4 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain AAA_12 PF13087.6 GAX09360.1 - 1.9e-47 161.5 0.0 4.2e-47 160.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 GAX09360.1 - 1.4e-40 139.3 0.0 2.6e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 GAX09360.1 - 1.3e-32 113.7 0.2 4.2e-16 59.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 GAX09360.1 - 3.8e-16 59.4 0.1 3.9e-15 56.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 GAX09360.1 - 2.9e-10 40.5 0.1 6.2e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.6 GAX09360.1 - 1.8e-09 38.1 0.0 4.9e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 GAX09360.1 - 5.4e-05 23.1 0.0 0.00036 20.4 0.0 2.2 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 GAX09360.1 - 0.00013 21.8 0.1 1.8 8.2 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 GAX09360.1 - 0.0015 18.6 0.0 0.0057 16.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF83 UvrD-helicase PF00580.21 GAX09360.1 - 0.0025 17.4 1.5 0.14 11.6 0.0 2.9 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 GAX09360.1 - 0.014 15.2 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SRP54 PF00448.22 GAX09360.1 - 0.029 14.0 0.2 0.91 9.1 0.1 2.3 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAX09360.1 - 0.031 14.6 0.1 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 GAX09360.1 - 0.054 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 GAX09360.1 - 0.061 13.3 0.0 0.71 9.8 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PseudoU_synth_2 PF00849.22 GAX09361.1 - 1.5e-20 73.9 0.0 2.4e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase YabA PF06156.13 GAX09362.1 - 0.0088 16.7 3.9 1 10.1 0.9 2.2 2 0 0 2 2 2 2 Initiation control protein YabA DUF4805 PF16063.5 GAX09362.1 - 0.012 15.0 0.8 0.015 14.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Unstab_antitox PF09720.10 GAX09362.1 - 0.019 15.0 0.1 0.049 13.7 0.1 1.7 1 0 0 1 1 1 0 Putative addiction module component Methyltransf_11 PF08241.12 GAX09363.1 - 2e-17 63.6 0.1 7.2e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX09363.1 - 5.4e-14 52.4 0.0 1.1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX09363.1 - 6.2e-13 49.3 0.0 1.6e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX09363.1 - 1.7e-10 41.5 0.0 4e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX09363.1 - 6.3e-09 35.8 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX09363.1 - 4.1e-07 29.6 0.0 7.9e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 GAX09363.1 - 0.00033 19.4 0.0 0.00054 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_7 PF03492.15 GAX09363.1 - 0.04 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase N6_N4_Mtase PF01555.18 GAX09363.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA methylase CENP-C_C PF11699.8 GAX09364.1 - 2.2e-06 27.8 0.0 0.0061 16.7 0.0 2.9 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_2 PF07883.11 GAX09364.1 - 0.054 13.2 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 Cupin domain TFIIF_alpha PF05793.12 GAX09366.1 - 1.1 7.7 18.0 1.6 7.2 18.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CR6_interact PF10147.9 GAX09366.1 - 1.2 8.8 8.3 7.4 6.2 0.3 2.1 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 MRI PF15325.6 GAX09366.1 - 1.8 9.7 14.5 0.59 11.2 1.3 2.6 1 1 1 2 2 2 0 Modulator of retrovirus infection SPAN-X PF07458.12 GAX09366.1 - 3.6 8.1 9.4 0.51 10.8 2.0 2.4 1 1 1 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome ATG_C PF09333.11 GAX09367.1 - 1.4e-15 57.4 0.0 3.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 GAX09367.1 - 1.8e-05 24.8 0.0 0.00018 21.6 0.0 2.6 1 1 1 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 GAX09367.1 - 5.3e-05 23.1 0.4 0.00023 21.0 0.0 2.2 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 GAX09367.1 - 0.00036 20.3 1.0 0.00075 19.3 0.2 2.0 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif HSP70 PF00012.20 GAX09369.1 - 9.7e-78 261.8 17.7 3.3e-63 213.8 0.0 4.5 2 2 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 GAX09369.1 - 2.1e-11 43.2 3.1 1.3e-08 34.0 0.1 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GAX09369.1 - 6.9e-05 22.7 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAX09369.1 - 0.45 11.0 2.9 12 6.4 0.0 3.4 3 1 0 3 3 3 0 Cell division protein FtsA DUF4239 PF14023.6 GAX09370.1 - 1.7e-19 70.4 0.4 2.5e-19 69.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) RNA_pol_3_Rpc31 PF11705.8 GAX09371.1 - 0.0011 19.3 0.5 0.0019 18.5 0.5 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 GAX09371.1 - 1.8 7.6 5.4 2.5 7.2 5.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GP67 PF17634.2 GAX09371.1 - 1.9 8.9 12.8 3.8 8.0 12.8 1.5 1 0 0 1 1 1 0 Gene product 67 Ank_4 PF13637.6 GAX09372.1 - 0.032 14.8 0.5 0.98 10.1 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX09373.1 - 0.024 14.9 0.0 10 6.6 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 GAX09373.1 - 0.13 12.8 0.0 0.54 10.8 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 GAX09373.1 - 0.22 12.2 1.9 77 4.4 0.0 4.3 5 0 0 5 5 5 0 Ankyrin repeat Spore_coat_CotO PF14153.6 GAX09373.1 - 7 6.5 6.4 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Clat_adaptor_s PF01217.20 GAX09374.1 - 5.4e-36 123.6 2.5 1e-35 122.7 2.5 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_C78 PF07910.13 GAX09375.1 - 2.2e-28 99.2 0.1 3.6e-28 98.5 0.1 1.3 1 1 0 1 1 1 1 Peptidase family C78 Guanylate_cyc_2 PF09778.9 GAX09375.1 - 0.019 14.3 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Guanylylate cyclase RRM_DME PF15628.6 GAX09375.1 - 0.1 12.8 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 RRM in Demeter SET PF00856.28 GAX09376.1 - 2e-09 38.0 0.0 1.2e-08 35.5 0.0 2.1 2 1 0 2 2 2 1 SET domain TPR_4 PF07721.14 GAX09376.1 - 0.12 13.1 0.3 37 5.3 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX09376.1 - 0.15 12.3 0.1 4.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RXT2_N PF08595.11 GAX09376.1 - 0.31 11.1 5.2 0.37 10.8 2.3 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 GAX09376.1 - 2.1 8.0 10.9 3.5 7.3 10.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAX09376.1 - 6.4 6.0 10.9 9.8 5.4 10.9 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GAX09376.1 - 9.2 4.2 10.2 16 3.4 10.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 GAX09376.1 - 9.8 6.6 17.8 28 5.2 17.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sel1 PF08238.12 GAX09377.1 - 4.5e-11 43.0 0.2 0.24 12.1 0.0 7.2 7 1 0 7 7 7 3 Sel1 repeat DUF4972 PF16342.5 GAX09377.1 - 0.053 13.2 2.6 0.073 12.8 0.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4972) DUF4924 PF16271.5 GAX09377.1 - 0.056 13.5 1.5 1.2 9.2 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4924) DUF5308 PF17233.2 GAX09377.1 - 0.069 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) MatP_C PF17414.2 GAX09377.1 - 0.085 13.1 1.0 0.35 11.1 1.0 2.1 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain Spore_III_AB PF09548.10 GAX09377.1 - 0.095 12.8 2.4 0.17 12.0 2.4 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Cupin_3 PF05899.12 GAX09378.1 - 1.1e-29 102.0 3.9 1.4e-29 101.5 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GAX09378.1 - 4.6e-07 29.5 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 GAX09378.1 - 0.00062 19.6 0.0 0.00066 19.5 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 GAX09378.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF2061 PF09834.9 GAX09379.1 - 5e-24 84.6 10.1 1.5e-14 54.2 4.0 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2061) GOLGA2L5 PF15070.6 GAX09379.1 - 0.029 13.1 0.3 0.038 12.6 0.3 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 IncD PF17628.2 GAX09379.1 - 0.54 10.0 5.2 7 6.4 0.4 2.2 1 1 1 2 2 2 0 Inclusion membrane protein D zf-C3HC PF07967.13 GAX09380.1 - 4.7e-19 68.7 0.5 4.1e-17 62.5 0.1 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 GAX09380.1 - 0.041 14.0 3.0 0.42 10.8 0.1 2.5 2 1 0 2 2 2 0 Rsm1-like CNOT11 PF10155.9 GAX09381.1 - 3.2e-47 159.8 0.8 7.3e-47 158.6 0.8 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 COR PF16095.5 GAX09381.1 - 0.061 13.1 0.6 0.39 10.5 0.1 2.3 2 1 0 2 2 2 0 C-terminal of Roc, COR, domain ABC_tran PF00005.27 GAX09382.1 - 1.8e-15 57.7 0.5 1.5e-14 54.7 0.5 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAX09382.1 - 3e-11 43.7 4.8 5e-06 26.5 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX09382.1 - 0.00033 20.3 0.1 0.00079 19.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 GAX09382.1 - 0.00093 18.7 0.2 0.82 9.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 GAX09382.1 - 0.014 15.6 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAX09382.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 GAX09382.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 GAX09382.1 - 0.046 14.2 0.0 0.094 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX09382.1 - 0.05 13.5 0.4 0.2 11.5 0.0 2.1 2 1 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 GAX09382.1 - 0.052 13.9 0.2 0.088 13.2 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAX09382.1 - 0.053 13.8 0.4 0.29 11.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 GAX09382.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAX09382.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase CLP1_P PF16575.5 GAX09382.1 - 0.13 12.1 0.0 0.81 9.5 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Patatin PF01734.22 GAX09383.1 - 3.9e-08 33.7 0.4 2.3e-07 31.2 0.4 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1269 PF06897.12 GAX09383.1 - 0.16 12.3 0.2 0.31 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Paf1 PF03985.13 GAX09384.1 - 5.1e-31 108.1 8.6 5.1e-31 108.1 8.6 3.5 2 1 0 2 2 2 1 Paf1 Iron_traffic PF04362.14 GAX09384.1 - 0.012 15.2 0.4 0.029 14.1 0.4 1.6 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Lsr2 PF11774.8 GAX09384.1 - 6 7.0 9.4 0.23 11.6 1.5 2.5 2 0 0 2 2 2 0 Lsr2 APG6_N PF17675.1 GAX09384.1 - 7.2 7.1 19.7 2.7 8.5 4.6 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region Methyltransf_25 PF13649.6 GAX09385.1 - 5.8e-07 30.1 0.0 1.6e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GAX09385.1 - 2.6e-06 27.1 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAX09385.1 - 3.8e-06 27.4 0.0 7.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX09385.1 - 1.5e-05 24.8 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX09385.1 - 2.5e-05 23.9 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAX09385.1 - 0.00015 22.4 0.0 0.00027 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX09385.1 - 0.0009 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPR_2 PF07719.17 GAX09386.1 - 8.4e-08 31.8 0.9 0.07 13.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX09386.1 - 2.8e-07 30.7 0.7 0.058 13.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX09386.1 - 6.5e-07 28.9 0.6 0.29 11.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX09386.1 - 5e-05 23.0 2.4 0.35 11.0 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX09386.1 - 0.00024 20.9 1.7 0.1 12.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX09386.1 - 0.012 16.3 0.9 6.6 7.8 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX09386.1 - 0.09 13.0 1.0 35 4.9 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Kelch_5 PF13854.6 GAX09388.1 - 1.2e-10 41.2 8.4 0.00075 19.4 0.1 5.5 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GAX09388.1 - 5.3e-09 36.1 1.0 0.066 13.5 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAX09388.1 - 2.5e-08 33.8 10.7 0.32 11.0 0.0 6.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAX09388.1 - 9.5e-08 32.1 12.8 0.013 15.8 0.0 7.1 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAX09388.1 - 0.00012 21.9 9.0 0.89 9.6 0.1 5.5 5 0 0 5 5 5 3 Kelch motif DUF3638 PF12340.8 GAX09389.1 - 6.1e-24 84.6 0.1 2.2e-21 76.2 0.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 GAX09389.1 - 1.7e-13 49.7 0.1 4.2e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.6 GAX09389.1 - 1.1e-11 45.0 2.2 5.2e-09 36.4 0.3 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX09389.1 - 8.5e-11 40.6 4.4 4.8e-05 22.6 0.3 4.4 4 0 0 4 4 4 2 EF hand Vps62 PF06101.11 GAX09389.1 - 9.3e-09 34.1 0.0 1.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 EF-hand_5 PF13202.6 GAX09389.1 - 9.8e-07 28.0 4.5 0.0045 16.4 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GAX09389.1 - 1.3e-05 24.7 12.0 0.025 14.5 0.2 4.8 5 0 0 5 5 5 2 EF-hand domain SH3_9 PF14604.6 GAX09389.1 - 0.00032 20.5 0.1 0.001 18.9 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAX09389.1 - 0.004 16.8 0.1 0.0093 15.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAX09389.1 - 0.0056 16.3 0.4 0.015 14.9 0.4 1.7 1 0 0 1 1 1 1 SH3 domain EF-hand_8 PF13833.6 GAX09389.1 - 0.045 13.6 5.8 0.097 12.5 1.1 3.3 3 1 1 4 4 4 0 EF-hand domain pair DNA_pol_phi PF04931.13 GAX09389.1 - 6.6 4.7 18.7 11 4.0 18.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi HSF_DNA-bind PF00447.17 GAX09390.1 - 6.9e-17 61.9 0.2 3.2e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding PG_binding_1 PF01471.18 GAX09390.1 - 0.087 13.0 0.3 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Acetyltransf_13 PF13880.6 GAX09391.1 - 4e-20 71.6 0.1 7.6e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 GAX09391.1 - 2.4e-14 52.9 0.1 4.3e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 GAX09391.1 - 0.0016 18.8 0.0 0.0059 17.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX09391.1 - 0.0051 17.0 0.0 0.0081 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAX09391.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein RhoGAP PF00620.27 GAX09393.1 - 4.9e-15 55.7 0.0 8.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 GAX09393.1 - 8.7e-09 35.2 0.1 1.5e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_25 PF13481.6 GAX09394.1 - 2.5e-08 33.8 1.3 3.8e-06 26.6 0.2 3.1 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 GAX09394.1 - 1.5e-05 24.5 0.5 0.14 11.5 0.1 2.4 2 0 0 2 2 2 2 KaiC Rad51 PF08423.11 GAX09394.1 - 3.3e-05 23.3 0.6 0.036 13.3 0.1 2.2 2 0 0 2 2 2 2 Rad51 AAA_33 PF13671.6 GAX09394.1 - 3.6e-05 24.0 0.2 0.00011 22.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAX09394.1 - 0.00014 22.2 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX09394.1 - 0.0048 17.2 0.1 0.024 14.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 GAX09394.1 - 0.0048 17.3 0.0 0.0097 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 GAX09394.1 - 0.02 14.3 0.1 0.26 10.7 0.0 2.5 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAX09394.1 - 0.031 14.7 2.5 0.14 12.5 0.2 2.9 2 1 0 3 3 3 0 AAA ATPase domain PIN_10 PF18478.1 GAX09394.1 - 0.08 13.2 0.5 0.74 10.1 0.5 2.3 2 0 0 2 2 2 0 PIN like domain DAP3 PF10236.9 GAX09394.1 - 0.13 11.4 0.8 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 GAX09394.1 - 0.13 12.8 0.4 0.61 10.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain cobW PF02492.19 GAX09394.1 - 0.15 11.7 0.5 0.43 10.1 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CENP-B_dimeris PF09026.10 GAX09394.1 - 0.19 12.1 6.8 0.48 10.8 6.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GAX09394.1 - 0.26 10.6 3.7 0.39 10.0 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1206 PF06724.11 GAX09395.1 - 0.19 11.8 2.3 0.5 10.5 0.8 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF4523 PF15023.6 GAX09396.1 - 0.015 15.2 0.5 0.41 10.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_1 PF00076.22 GAX09396.1 - 0.061 13.1 0.0 0.25 11.2 0.0 2.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3727 PF12527.8 GAX09398.1 - 9.8e-08 32.1 11.9 0.0015 18.8 0.1 4.5 2 2 2 5 5 5 3 Protein of unknown function (DUF3727) UAA PF08449.11 GAX09399.1 - 7.3e-52 176.4 23.6 7.3e-52 176.4 23.6 1.9 3 0 0 3 3 3 1 UAA transporter family EamA PF00892.20 GAX09399.1 - 1.2e-06 28.8 12.4 1.2e-06 28.8 12.4 4.1 4 1 0 4 4 4 2 EamA-like transporter family 7TM-7TMR_HD PF07698.11 GAX09399.1 - 0.00069 19.4 15.4 0.00069 19.4 15.4 4.6 4 1 0 4 4 4 1 7TM receptor with intracellular HD hydrolase Adeno_PV PF03910.13 GAX09399.1 - 0.17 10.6 0.2 0.25 10.0 0.2 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF4834 PF16118.5 GAX09399.1 - 1.9 9.5 0.0 1.9 9.5 0.0 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4834) Dcc1 PF09724.9 GAX09400.1 - 2e-29 103.0 1.2 2.5e-29 102.6 1.2 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HTH_11 PF08279.12 GAX09400.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 HTH domain Kinesin PF00225.23 GAX09401.1 - 4.4e-85 285.5 0.9 4.4e-85 285.5 0.9 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX09401.1 - 3.1e-13 49.9 0.1 7.1e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 GAX09401.1 - 0.044 14.2 0.0 0.22 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 GAX09401.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4559 PF15112.6 GAX09401.1 - 0.34 10.6 4.0 0.64 9.6 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) CDC45 PF02724.14 GAX09402.1 - 0.19 10.0 9.0 0.17 10.2 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAX09402.1 - 1.6 6.7 19.3 2 6.4 19.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GAX09402.1 - 2.8 7.2 10.3 4.2 6.6 10.3 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 GAX09402.1 - 7 5.1 12.5 8.8 4.7 12.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CSRNP_N PF16019.5 GAX09402.1 - 9 6.1 7.7 12 5.8 5.2 2.2 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus TPD PF14811.6 GAX09403.1 - 8.4e-37 126.1 0.0 1.4e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif Cyt-b5 PF00173.28 GAX09404.1 - 1.9e-07 31.1 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SAPS PF04499.15 GAX09404.1 - 0.012 14.5 0.1 0.014 14.2 0.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CTP_transf_like PF01467.26 GAX09405.1 - 9.7e-36 123.1 0.0 7.5e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 GAX09405.1 - 0.0044 16.9 0.3 1.8 8.5 0.1 3.3 2 1 0 2 2 2 2 FAD synthetase EutQ PF06249.12 GAX09405.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DUF1403 PF07183.11 GAX09406.1 - 0.069 12.7 1.2 0.1 12.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) NOG1_N PF17835.1 GAX09407.1 - 3.6e-52 176.5 2.6 5.3e-52 176.0 0.1 2.3 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 GAX09407.1 - 1.2e-26 92.2 0.5 2.9e-26 91.0 0.5 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 GAX09407.1 - 2.6e-24 85.0 2.8 5.6e-24 83.9 2.8 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 GAX09407.1 - 5.8e-17 61.8 0.0 3.5e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX09407.1 - 8.9e-09 35.1 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 GAX09407.1 - 0.0017 17.7 0.0 0.0048 16.3 0.0 1.8 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 GAX09407.1 - 0.0064 16.1 0.0 0.015 14.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAX09407.1 - 0.077 13.2 0.1 0.86 9.8 0.1 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAX09407.1 - 0.087 12.7 0.7 2.1 8.2 0.1 3.0 2 1 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 GAX09408.1 - 1.3e-49 168.4 0.0 7.9e-47 159.3 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX09408.1 - 8.2e-18 64.2 0.0 2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GAX09408.1 - 2.5e-15 56.3 0.1 7.6e-15 54.8 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 GAX09408.1 - 1.4e-06 28.0 0.0 0.00042 20.1 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 GAX09408.1 - 3.8e-06 27.2 0.1 9.6e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AvrPtoB_bdg PF16847.5 GAX09408.1 - 0.0013 19.2 0.0 0.034 14.6 0.0 2.7 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain RF3_C PF16658.5 GAX09408.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Imm53 PF15580.6 GAX09408.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 53 SRPRB PF09439.10 GAX09408.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Nuc_sug_transp PF04142.15 GAX09409.1 - 1.2e-83 280.9 17.2 1.4e-83 280.7 17.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAX09409.1 - 3.1e-15 56.2 16.3 4.6e-15 55.6 16.0 1.4 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 GAX09409.1 - 3.5e-06 26.5 17.4 5.1e-06 25.9 17.3 1.3 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 GAX09409.1 - 4.3e-05 22.6 6.1 4.3e-05 22.6 6.1 2.3 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAX09409.1 - 0.00012 22.2 23.2 0.0039 17.4 9.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAX09409.1 - 0.5 9.7 16.2 0.26 10.6 12.3 2.1 1 1 1 2 2 2 0 Triose-phosphate Transporter family DMT_6 PF04342.12 GAX09409.1 - 1.2 9.3 12.0 0.19 12.0 0.6 3.8 2 2 1 4 4 4 0 Putative member of DMT superfamily (DUF486) 2Fe-2S_thioredx PF01257.19 GAX09410.1 - 2.3e-55 186.5 0.4 2.7e-55 186.2 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin PAS_9 PF13426.7 GAX09413.1 - 2e-17 63.3 0.0 4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 GAX09413.1 - 2.5e-07 30.7 11.7 4.5e-07 29.8 11.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX09413.1 - 7.8e-06 25.9 5.6 1.4e-05 25.1 5.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 GAX09413.1 - 1.6e-05 25.1 0.0 4.5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GAX09413.1 - 0.04 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 GAX09413.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 PAS fold Glyco_transf_7C PF02709.14 GAX09413.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase RestrictionMunI PF11407.8 GAX09413.1 - 0.16 11.6 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI Med6 PF04934.14 GAX09414.1 - 1.9e-24 85.9 0.0 2.6e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF4272 PF14094.6 GAX09415.1 - 1.2 8.4 3.6 7.7 5.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4272) MAS20 PF02064.15 GAX09415.1 - 2.5 8.2 7.1 5.2 7.2 6.7 1.7 1 1 0 1 1 1 0 MAS20 protein import receptor G6PD_C PF02781.16 GAX09418.1 - 8.7e-83 277.9 0.0 1.1e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAX09418.1 - 2.1e-48 165.3 0.0 3.1e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Acetyltransf_2 PF00797.17 GAX09419.1 - 4.5e-34 118.3 0.0 2.4e-33 115.9 0.0 1.8 1 1 0 1 1 1 1 N-acetyltransferase FG-GAP_2 PF14312.6 GAX09420.1 - 3.8e-50 167.9 27.6 7.3e-09 35.8 1.3 7.3 7 0 0 7 7 7 7 FG-GAP repeat PQQ_3 PF13570.6 GAX09420.1 - 0.11 13.0 5.8 0.82 10.2 0.1 4.5 4 0 0 4 4 4 0 PQQ-like domain Aminotran_1_2 PF00155.21 GAX09421.1 - 2.5e-33 115.7 0.0 4.9e-33 114.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 GAX09421.1 - 0.0044 16.0 0.0 0.0086 15.0 0.0 1.5 1 0 0 1 1 1 1 Allinase Ribosomal_L32p PF01783.23 GAX09422.1 - 0.14 12.4 0.3 16 5.8 0.1 2.9 2 0 0 2 2 2 0 Ribosomal L32p protein family Chloroa_b-bind PF00504.21 GAX09424.1 - 1e-33 117.1 0.1 1.3e-33 116.8 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein BTB PF00651.31 GAX09427.1 - 0.0086 16.3 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Mob_synth_C PF06463.13 GAX09428.1 - 3.9e-29 101.2 0.0 8.9e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 GAX09428.1 - 5e-28 98.6 0.0 7.3e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAX09428.1 - 4.9e-09 36.6 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GAX09428.1 - 0.0019 18.3 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Oxidored_molyb PF00174.19 GAX09430.1 - 5.8e-53 179.0 0.0 9.6e-53 178.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAX09430.1 - 1.3e-41 141.8 1.4 1.3e-41 141.8 1.4 1.6 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 GAX09430.1 - 9.5e-32 109.3 0.0 3.5e-31 107.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAX09430.1 - 3.2e-25 88.9 0.0 8.5e-25 87.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 GAX09430.1 - 4.3e-22 78.0 0.1 8.7e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 GAX09430.1 - 2.5e-06 27.7 0.0 3.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 GAX09431.1 - 1.6e-16 60.9 0.0 2.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ank_5 PF13857.6 GAX09432.1 - 1.3e-06 28.5 0.0 0.0017 18.7 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX09432.1 - 1.9e-06 27.7 0.0 0.71 10.6 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 GAX09432.1 - 5e-06 27.0 0.0 0.00075 20.0 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX09432.1 - 0.00034 20.9 0.2 0.19 12.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat GIY-YIG PF01541.24 GAX09432.1 - 0.091 13.0 1.4 0.93 9.8 0.3 2.4 2 0 0 2 2 2 0 GIY-YIG catalytic domain Lipoprotein_6 PF01441.19 GAX09432.1 - 0.86 9.6 8.9 0.085 12.9 2.2 2.2 1 1 1 2 2 2 0 Lipoprotein Tho2 PF11262.8 GAX09432.1 - 7.8 5.6 15.8 0.21 10.7 7.6 2.3 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Ank_2 PF12796.7 GAX09433.1 - 1.3e-31 109.0 0.1 1.5e-09 38.3 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX09433.1 - 1.4e-26 89.6 6.5 0.051 14.1 0.0 9.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 GAX09433.1 - 9.3e-26 89.9 4.0 6.7e-05 23.4 0.1 6.9 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX09433.1 - 2e-24 85.3 0.2 4.6e-05 23.6 0.0 6.5 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 GAX09433.1 - 3.3e-15 55.8 5.1 0.0014 19.0 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat DUF5492 PF17596.2 GAX09433.1 - 0.00012 22.3 0.2 35 4.8 0.0 5.4 5 0 0 5 5 5 0 Family of unknown function (DUF5492) HlyD_2 PF12700.7 GAX09433.1 - 0.19 10.4 0.8 0.28 9.9 0.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein TSP_1 PF00090.19 GAX09434.1 - 6.6e-11 42.2 117.7 1.8e-05 24.8 7.8 8.6 8 0 0 8 8 8 7 Thrombospondin type 1 domain DUF3419 PF11899.8 GAX09436.1 - 1.6e-69 235.0 0.0 4.4e-69 233.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 GAX09436.1 - 6.3e-16 58.7 0.0 1.5e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX09436.1 - 4e-08 33.9 0.0 8.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX09436.1 - 2.2e-07 31.5 0.0 9e-06 26.3 0.0 3.2 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX09436.1 - 3.4e-07 29.8 0.0 6.1e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GAX09436.1 - 8.4e-06 26.4 0.0 3.3e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX09436.1 - 2.3e-05 24.2 0.0 5.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP2C PF00481.21 GAX09437.1 - 8.2e-48 163.3 0.1 1.6e-47 162.3 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Ank_2 PF12796.7 GAX09437.1 - 7.6e-07 29.6 0.1 2.2e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX09437.1 - 2.4e-06 27.7 1.0 0.044 14.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAX09437.1 - 9.2e-05 22.9 0.1 0.0003 21.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX09437.1 - 0.00011 22.3 0.1 0.68 10.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAX09437.1 - 0.0003 21.0 0.2 0.049 14.0 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) PP2C_2 PF13672.6 GAX09437.1 - 0.00078 19.1 0.9 0.00078 19.1 0.9 2.3 3 1 0 3 3 3 1 Protein phosphatase 2C R3H-assoc PF13902.6 GAX09438.1 - 0.034 14.5 2.6 0.21 12.0 2.6 2.1 1 1 0 1 1 1 0 R3H-associated N-terminal domain MGDG_synth PF06925.11 GAX09439.1 - 4.3e-23 82.3 0.0 6.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 GAX09439.1 - 1.2e-10 41.6 0.0 1.5e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 GAX09439.1 - 4.4e-05 23.1 0.1 0.00081 19.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX09439.1 - 0.00037 20.9 0.3 0.0016 18.9 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX09439.1 - 0.15 12.0 0.0 0.69 9.9 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase Family 4 DUF4834 PF16118.5 GAX09440.1 - 0.0036 18.2 0.3 0.042 14.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Med13_C PF06333.12 GAX09440.1 - 1 8.5 10.8 0.1 11.8 0.9 2.2 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Arginosuc_synth PF00764.19 GAX09441.1 - 2.4e-152 507.7 0.0 2.9e-152 507.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 GAX09441.1 - 0.0032 17.0 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAX09441.1 - 0.0097 14.7 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase His_Phos_2 PF00328.22 GAX09442.1 - 1.5e-13 50.9 1.2 1.5e-10 41.0 0.5 2.8 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Phytase-like PF13449.6 GAX09443.1 - 1e-39 137.2 1.3 7.3e-39 134.4 0.1 2.6 3 0 0 3 3 3 1 Esterase-like activity of phytase Cytochrom_D1 PF02239.16 GAX09443.1 - 0.04 12.5 0.6 0.16 10.5 0.1 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain LOR PF04525.12 GAX09443.1 - 0.07 12.7 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 LURP-one-related LVIVD PF08309.11 GAX09443.1 - 0.08 12.3 6.6 7.1 6.0 0.0 4.6 4 0 0 4 4 4 0 LVIVD repeat NHL PF01436.21 GAX09443.1 - 0.1 12.7 2.2 36 4.7 0.1 4.8 5 0 0 5 5 5 0 NHL repeat PT PF04886.12 GAX09443.1 - 1 8.9 6.3 2.1 7.9 6.3 1.5 1 0 0 1 1 1 0 PT repeat TPR_1 PF00515.28 GAX09444.1 - 1.3e-07 31.1 3.6 0.11 12.3 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX09444.1 - 1.4e-06 28.2 0.1 1.1 9.8 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX09444.1 - 2.3e-06 27.3 6.9 0.3 11.3 0.0 6.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX09444.1 - 1.8e-05 25.2 2.0 1 10.4 0.2 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX09444.1 - 0.00014 22.2 1.7 0.88 10.1 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX09444.1 - 0.00015 21.3 1.1 4 7.2 0.0 5.5 4 2 2 6 6 6 1 TPR repeat TPR_16 PF13432.6 GAX09444.1 - 0.00026 21.5 0.9 0.082 13.6 0.1 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX09444.1 - 0.0025 17.9 0.2 0.85 9.8 0.1 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX09444.1 - 0.006 16.0 0.4 0.033 13.6 0.1 2.1 3 0 0 3 3 3 1 MalT-like TPR region TPR_7 PF13176.6 GAX09444.1 - 0.0067 16.4 3.3 1.3 9.2 0.0 4.5 6 1 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 GAX09444.1 - 0.012 15.9 0.0 0.28 11.5 0.0 3.0 2 0 0 2 2 2 0 PPR repeat TPR_12 PF13424.6 GAX09444.1 - 0.037 14.3 4.9 2.4 8.5 0.6 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAX09444.1 - 0.077 13.3 2.1 6.1 7.2 0.4 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF5486 PF17588.2 GAX09444.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5486) ANAPC3 PF12895.7 GAX09444.1 - 0.14 12.4 2.0 13 6.0 0.3 3.4 2 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAX09444.1 - 0.15 12.3 6.6 1.1e+02 3.4 0.0 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX09444.1 - 0.16 12.7 0.2 1.6e+02 3.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX09444.1 - 1.4 8.9 4.0 9.2 6.3 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat OTU PF02338.19 GAX09445.1 - 7.3e-07 29.7 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DnaJ PF00226.31 GAX09446.1 - 1.8e-14 53.6 0.3 3.6e-14 52.6 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2637 PF10935.8 GAX09446.1 - 0.0095 15.8 1.0 0.016 15.1 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2637) DUF3561 PF12084.8 GAX09446.1 - 0.011 15.7 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) TerC PF03741.16 GAX09446.1 - 7.9 6.1 13.4 0.24 11.1 3.2 2.3 2 1 0 2 2 2 0 Integral membrane protein TerC family Gpi16 PF04113.14 GAX09448.1 - 2.5e-16 59.3 0.0 3.1e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF1995 PF09353.10 GAX09449.1 - 5.6e-25 88.5 0.1 1.6e-24 87.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) SBP_bac_5 PF00496.22 GAX09450.1 - 0.083 11.8 0.0 0.086 11.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle TPR_12 PF13424.6 GAX09451.1 - 2.3e-11 43.8 4.1 4.5e-05 23.7 1.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX09451.1 - 6.8e-09 35.2 14.5 0.027 14.3 0.2 6.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX09451.1 - 2.7e-08 33.3 3.0 0.014 15.4 0.5 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX09451.1 - 3.1e-08 33.2 9.1 0.016 15.3 0.4 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX09451.1 - 2.2e-06 27.4 15.0 1.3 9.3 0.3 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat Methyltransf_25 PF13649.6 GAX09451.1 - 5.5e-05 23.8 0.1 0.00016 22.3 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_16 PF13432.6 GAX09451.1 - 0.00011 22.8 3.2 0.016 15.8 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX09451.1 - 0.00079 19.6 3.6 13 6.5 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX09451.1 - 0.0028 17.5 6.1 0.029 14.3 0.8 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Methyltransf_11 PF08241.12 GAX09451.1 - 0.0029 18.2 0.0 0.0073 16.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPR_6 PF13174.6 GAX09451.1 - 0.0035 17.9 2.9 13 6.6 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 GAX09451.1 - 0.0058 16.4 0.3 0.044 13.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX09451.1 - 0.018 14.9 0.1 0.051 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX09451.1 - 0.038 14.7 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MIT PF04212.18 GAX09451.1 - 0.073 13.2 12.3 0.41 10.8 0.0 4.4 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain MTS PF05175.14 GAX09451.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DUF627 PF04781.12 GAX09451.1 - 0.2 11.6 4.0 0.95 9.5 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_11 PF13414.6 GAX09451.1 - 0.52 10.0 16.8 4.1 7.2 0.6 5.2 6 0 0 6 6 6 0 TPR repeat TPR_14 PF13428.6 GAX09451.1 - 3.2 8.8 7.4 78 4.5 0.2 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat DHR10 PF18595.1 GAX09453.1 - 0.0059 16.6 17.8 0.02 15.0 16.0 2.1 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain GatB_Yqey PF02637.18 GAX09453.1 - 0.016 15.1 2.2 0.024 14.5 2.2 1.2 1 0 0 1 1 1 0 GatB domain DUF2202 PF09968.9 GAX09453.1 - 0.017 15.0 1.0 0.026 14.4 1.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) RPAP3_C PF13877.6 GAX09453.1 - 0.022 15.3 2.0 0.04 14.5 2.0 1.4 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 ApoLp-III PF07464.11 GAX09453.1 - 0.029 14.5 6.3 0.61 10.2 6.1 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CENP-H PF05837.12 GAX09453.1 - 0.029 14.8 5.5 0.051 14.0 5.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 GAX09453.1 - 0.032 13.8 2.9 0.041 13.4 2.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3837 PF12939.7 GAX09453.1 - 0.049 14.0 2.5 0.069 13.5 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3837) Syntaxin_2 PF14523.6 GAX09453.1 - 0.061 13.7 7.7 0.051 14.0 5.8 1.9 1 1 1 2 2 2 0 Syntaxin-like protein UPF0242 PF06785.11 GAX09453.1 - 0.11 12.6 8.6 0.16 12.1 8.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2408 PF10303.9 GAX09453.1 - 0.11 13.0 7.6 0.23 12.0 7.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) MCPsignal PF00015.21 GAX09453.1 - 0.13 12.0 2.3 0.24 11.2 2.3 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 GAX09453.1 - 0.15 12.1 7.1 6.8 6.8 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 GAX09453.1 - 0.23 10.7 8.1 0.38 10.0 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sec20 PF03908.13 GAX09453.1 - 0.32 10.9 3.6 0.44 10.5 1.7 2.0 1 1 1 2 2 2 0 Sec20 DUF1043 PF06295.12 GAX09453.1 - 0.44 10.6 6.4 0.67 10.0 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FlaC_arch PF05377.11 GAX09453.1 - 0.5 10.8 4.6 2.8 8.4 0.1 3.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 GAX09453.1 - 0.57 9.0 1.8 0.64 8.9 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.11 GAX09453.1 - 0.65 10.3 3.9 2.2 8.6 1.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2935 PF11155.8 GAX09453.1 - 0.67 10.3 6.8 3.6 7.9 6.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) TMPIT PF07851.13 GAX09453.1 - 0.87 8.8 7.8 1.3 8.2 7.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF883 PF05957.13 GAX09453.1 - 1.1 9.8 6.3 2.6 8.7 0.8 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Med9 PF07544.13 GAX09453.1 - 1.7 8.8 10.4 2 8.6 3.9 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 KNOX2 PF03791.13 GAX09453.1 - 3.5 7.2 9.9 1.4 8.5 0.8 3.1 1 1 2 3 3 3 0 KNOX2 domain Fzo_mitofusin PF04799.13 GAX09453.1 - 4.2 6.9 10.0 3.2 7.3 6.8 2.0 1 1 1 2 2 2 0 fzo-like conserved region Laminin_II PF06009.12 GAX09453.1 - 6.4 6.8 9.7 1.5 8.8 6.5 1.5 2 0 0 2 2 1 0 Laminin Domain II PRKG1_interact PF15898.5 GAX09453.1 - 8.7 7.3 14.0 1 10.3 5.1 2.4 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain efThoc1 PF11957.8 GAX09454.1 - 8.1e-32 110.5 7.1 1.5e-28 99.8 7.1 2.6 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor zf-Nse PF11789.8 GAX09455.1 - 4.8e-16 58.3 0.1 9.1e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 GAX09455.1 - 0.0037 17.1 0.1 0.0098 15.7 0.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 GAX09455.1 - 0.0039 16.9 0.3 0.0094 15.7 0.3 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger U-box PF04564.15 GAX09455.1 - 0.0044 17.2 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.6 GAX09455.1 - 0.0086 16.1 0.0 0.025 14.6 0.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX09455.1 - 0.085 13.2 0.2 0.2 12.0 0.2 1.7 1 0 0 1 1 1 0 Ring finger domain Mitoc_L55 PF09776.9 GAX09455.1 - 0.45 10.3 5.0 6.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 tRNA-synt_2 PF00152.20 GAX09456.1 - 3e-55 187.5 0.0 4.1e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX09456.1 - 1.3e-13 50.7 0.0 1.1e-12 47.7 0.1 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain WHEP-TRS PF00458.20 GAX09456.1 - 2.8e-08 33.8 0.7 5.3e-08 32.9 0.7 1.4 1 0 0 1 1 1 1 WHEP-TRS domain Use1 PF09753.9 GAX09456.1 - 0.016 14.9 0.6 0.027 14.2 0.6 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 tRNA-synt_2d PF01409.20 GAX09456.1 - 0.082 12.4 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DnaJ PF00226.31 GAX09457.1 - 1.9e-18 66.4 0.4 3.1e-18 65.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Chloroa_b-bind PF00504.21 GAX09458.1 - 1.8e-33 116.3 0.0 2.4e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NMT1 PF09084.11 GAX09459.1 - 5.9e-48 163.7 0.0 8.4e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Glyco_trans_1_2 PF13524.6 GAX09460.1 - 1.1e-10 41.8 0.1 4.2e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 FAT PF02259.23 GAX09460.1 - 0.0041 16.4 0.0 0.38 9.9 0.0 2.1 1 1 1 2 2 2 2 FAT domain Asp_Arg_Hydrox PF05118.15 GAX09461.1 - 1.7e-37 128.7 0.2 5.4e-37 127.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.17 GAX09461.1 - 0.12 12.6 1.0 3.4 8.0 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX09461.1 - 0.64 10.2 2.1 0.63 10.2 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Arm PF00514.23 GAX09462.1 - 6.8e-13 48.2 8.5 0.00042 20.3 0.1 8.5 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 GAX09462.1 - 6e-11 42.3 6.2 0.21 11.6 0.0 5.5 2 1 3 5 5 5 4 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.14 GAX09462.1 - 0.0026 17.1 2.8 0.09 12.0 0.8 3.2 1 1 1 2 2 2 1 V-ATPase subunit H DUF3361 PF11841.8 GAX09462.1 - 0.087 12.8 3.2 1.7 8.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Methyltransf_25 PF13649.6 GAX09463.1 - 1.3e-06 29.0 0.0 3.8e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GAX09463.1 - 3e-06 26.8 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAX09463.1 - 1.1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX09463.1 - 2.4e-05 24.0 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 GAX09463.1 - 2.8e-05 23.9 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAX09463.1 - 0.00023 21.9 0.0 0.00041 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX09463.1 - 0.0012 18.6 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_M1 PF01433.20 GAX09464.1 - 1.8e-48 165.0 0.1 3.4e-48 164.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GAX09464.1 - 1.5e-36 124.9 0.1 3.3e-36 123.8 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GAX09464.1 - 3.6e-25 89.2 0.0 5.6e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 GAX09464.1 - 0.35 11.3 1.9 6.7 7.1 2.0 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_S41 PF03572.18 GAX09465.1 - 2.5e-42 144.3 0.0 4.3e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GAX09465.1 - 1.3e-11 44.2 0.1 3.4e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX09465.1 - 2.6e-07 30.8 0.2 4.2e-06 27.0 0.1 2.8 2 1 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX09465.1 - 1.1e-06 28.9 0.2 2e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_C1 PF14684.6 GAX09465.1 - 2.2e-06 27.6 0.1 4.9e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Tricorn protease C1 domain DUF4199 PF13858.6 GAX09466.1 - 0.012 16.0 1.6 0.14 12.5 1.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) WD40 PF00400.32 GAX09469.1 - 2e-19 69.6 18.1 1.2e-06 29.2 0.2 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX09469.1 - 0.00061 20.0 0.7 0.078 13.3 0.0 4.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1681 PF07933.14 GAX09470.1 - 2.4e-47 160.4 0.0 2.8e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) LIDHydrolase PF10230.9 GAX09471.1 - 7.4e-33 114.2 0.0 1.6e-32 113.1 0.0 1.5 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 GAX09471.1 - 4.1e-06 26.2 0.0 6.6e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX09471.1 - 0.0095 15.6 0.1 0.13 11.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold FtsQ PF03799.15 GAX09472.1 - 0.017 15.9 2.2 0.07 14.0 2.0 2.3 1 1 0 1 1 1 0 Cell division protein FtsQ DUF5519 PF17648.1 GAX09472.1 - 0.054 13.4 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5519) DUF3677 PF12432.8 GAX09472.1 - 0.057 13.7 1.1 0.11 12.8 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) THOC7 PF05615.13 GAX09472.1 - 0.26 11.6 4.1 5.6 7.3 0.9 2.4 2 1 0 2 2 2 0 Tho complex subunit 7 Lipase_GDSL_2 PF13472.6 GAX09473.1 - 0.0028 18.1 0.0 0.0048 17.3 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX09473.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Branch PF02485.21 GAX09474.1 - 2.4e-14 53.5 0.2 5.4e-14 52.3 0.2 1.5 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ribosom_S12_S23 PF00164.25 GAX09475.1 - 9.7e-50 167.0 0.8 1.2e-49 166.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF3727 PF12527.8 GAX09476.1 - 1.8e-19 69.8 6.7 1.8e-19 69.8 6.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3727) RXT2_N PF08595.11 GAX09476.1 - 0.084 12.9 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PB1 PF00564.24 GAX09476.1 - 0.13 12.2 0.5 0.13 12.2 0.5 1.8 1 1 1 2 2 2 0 PB1 domain E7 PF00527.18 GAX09476.1 - 0.21 11.8 3.3 1.2 9.4 3.3 2.0 1 1 0 1 1 1 0 E7 protein, Early protein NOA36 PF06524.12 GAX09476.1 - 9 5.5 6.6 13 5.0 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein VIR_N PF15912.5 GAX09477.1 - 1.3 8.5 3.8 1.7 8.2 3.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal AAA_11 PF13086.6 GAX09477.1 - 7.3 6.3 6.9 8.9 6.0 6.9 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX09478.1 - 7.8e-09 36.1 0.4 1.5e-08 35.2 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX09478.1 - 0.00014 22.2 0.1 0.0069 16.7 0.0 2.9 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 GAX09478.1 - 0.00041 19.8 0.1 0.0009 18.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial TniB protein DAP3 PF10236.9 GAX09478.1 - 0.0083 15.3 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.14 GAX09478.1 - 0.025 14.6 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX09478.1 - 0.031 13.4 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAX09478.1 - 0.042 14.4 0.0 0.096 13.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 GAX09478.1 - 0.057 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAX09478.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GAX09478.1 - 0.062 13.5 0.1 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAX09478.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAX09478.1 - 0.089 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAX09478.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAX09478.1 - 0.18 12.2 0.0 3 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NMO PF03060.15 GAX09479.1 - 9e-35 120.6 0.9 1.9e-29 103.1 1.0 2.8 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 GAX09479.1 - 2.4e-14 53.1 0.1 4.9e-14 52.1 0.1 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAX09479.1 - 1.9e-09 37.0 0.8 1.9e-09 37.0 0.8 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAX09479.1 - 0.0039 16.4 0.6 0.0063 15.7 0.6 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF1729 PF08354.10 GAX09479.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) ThiG PF05690.14 GAX09479.1 - 0.058 12.7 0.8 0.34 10.2 0.1 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DHQS PF01959.16 GAX09479.1 - 0.058 12.3 0.7 2.1 7.2 0.0 2.4 3 0 0 3 3 3 0 3-dehydroquinate synthase II DEAD_2 PF06733.15 GAX09480.1 - 6.1e-46 156.2 0.1 2.6e-42 144.4 0.0 2.6 3 0 0 3 3 3 2 DEAD_2 Helicase_C_2 PF13307.6 GAX09480.1 - 1.1e-44 152.7 0.1 3.9e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 GAX09480.1 - 1.2e-25 90.4 0.1 1.2e-21 77.3 0.0 2.7 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 GAX09480.1 - 3.7e-08 33.6 0.0 0.00054 20.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX09480.1 - 5.7e-05 23.0 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF2075 PF09848.9 GAX09480.1 - 0.0079 15.5 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 GAX09480.1 - 0.08 13.2 0.1 12 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GAX09480.1 - 0.13 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 GAX09480.1 - 0.14 11.9 0.5 0.37 10.6 0.0 1.9 3 0 0 3 3 3 0 AAA domain vATP-synt_E PF01991.18 GAX09480.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Cpn60_TCP1 PF00118.24 GAX09481.1 - 1.7e-84 284.2 14.8 2.4e-84 283.7 14.8 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FHA PF00498.26 GAX09482.1 - 4.9e-12 46.0 0.0 1.4e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAX09482.1 - 2.7e-05 24.4 0.0 0.00015 22.0 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Z1 PF10593.9 GAX09482.1 - 1.4 8.4 7.5 1.3 8.5 5.6 1.8 1 1 1 2 2 2 0 Z1 domain AAA_23 PF13476.6 GAX09482.1 - 1.7 9.1 23.4 0.86 10.1 8.1 2.2 2 0 0 2 2 2 0 AAA domain Hydrolase_3 PF08282.12 GAX09483.1 - 6.3e-38 131.0 0.0 9.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GAX09483.1 - 8.6e-09 35.3 0.4 4.8e-07 29.6 0.0 2.6 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GAX09483.1 - 7.8e-06 26.3 0.0 0.014 15.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX09483.1 - 0.13 12.7 0.0 16 5.8 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PDH PF02153.17 GAX09484.1 - 7.8e-12 44.7 0.0 4.7e-06 25.8 0.0 3.0 2 1 0 2 2 2 2 Prephenate dehydrogenase F420_oxidored PF03807.17 GAX09484.1 - 0.00015 22.2 0.1 0.00063 20.3 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAX09484.1 - 0.0035 16.7 0.0 0.0091 15.4 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAX09484.1 - 0.044 14.1 0.1 0.89 9.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 GAX09484.1 - 0.051 13.5 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Gp_dh_N PF00044.24 GAX09484.1 - 0.096 13.0 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K-box PF01486.17 GAX09484.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 K-box region DUF1104 PF06518.11 GAX09484.1 - 1.1 9.7 4.8 1.3 9.4 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Rieske PF00355.26 GAX09485.1 - 5.6e-16 58.3 0.0 9.3e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GAX09485.1 - 6.1e-06 26.3 0.0 2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Pheophorbide a oxygenase RNHCP PF12647.7 GAX09485.1 - 0.095 12.7 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 RNHCP domain zf-TFIIB PF13453.6 GAX09485.1 - 0.15 11.4 0.5 1.4 8.3 0.3 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger Ribul_P_3_epim PF00834.19 GAX09487.1 - 1.6e-40 138.6 0.0 1.8e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 GAX09487.1 - 0.0017 18.6 0.1 0.0031 17.7 0.1 1.4 1 0 0 1 1 1 1 Predicted Peptidoglycan domain ThiG PF05690.14 GAX09487.1 - 0.0038 16.6 0.1 0.0057 16.0 0.1 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAX09487.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.17 GAX09487.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.3 1 1 0 1 1 1 0 Thiamine monophosphate synthase Bestrophin PF01062.21 GAX09489.1 - 4.7e-27 95.2 1.9 6.9e-27 94.6 1.9 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1761 PF08570.10 GAX09489.1 - 0.025 14.8 1.1 0.025 14.8 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) FtsJ PF01728.19 GAX09490.1 - 5.4e-27 95.0 0.0 8e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cauli_VI PF01693.16 GAX09490.1 - 0.068 13.5 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Caulimovirus viroplasmin Bestrophin PF01062.21 GAX09491.1 - 1.4e-28 100.1 2.5 1.9e-28 99.7 2.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Chloroa_b-bind PF00504.21 GAX09492.1 - 4e-33 115.2 0.4 1.5e-32 113.4 0.0 1.8 2 0 0 2 2 2 1 Chlorophyll A-B binding protein DUF4148 PF13663.6 GAX09492.1 - 0.33 11.1 2.9 0.79 10.0 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) PsbM PF05151.12 GAX09493.1 - 0.00022 20.9 6.5 0.00034 20.4 0.5 2.9 2 1 0 2 2 2 1 Photosystem II reaction centre M protein (PsbM) YfhO PF09586.10 GAX09493.1 - 0.049 11.9 1.4 0.054 11.7 1.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO COA2 PF17051.5 GAX09493.1 - 0.15 12.1 2.0 0.17 12.0 0.1 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase assembly factor 2 Sugar_tr PF00083.24 GAX09494.1 - 1.1e-92 311.3 25.2 1.3e-92 311.1 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX09494.1 - 2.6e-32 112.1 34.1 2.7e-32 112.1 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UQ_con PF00179.26 GAX09495.1 - 2.8e-47 159.9 0.0 4.1e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 GAX09495.1 - 8.6e-08 31.9 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 GAX09495.1 - 0.00091 18.9 0.0 0.0016 18.1 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B UBA_4 PF14555.6 GAX09495.1 - 0.0084 15.9 0.2 0.02 14.7 0.1 1.7 2 0 0 2 2 2 1 UBA-like domain RWD PF05773.22 GAX09495.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain AMP-binding PF00501.28 GAX09496.1 - 1.9e-82 277.1 0.0 2.4e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 GAX09496.1 - 0.0079 16.2 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas2CT1978) UCR_UQCRX_QCR9 PF05365.12 GAX09498.1 - 0.00028 20.8 2.1 0.00049 20.0 2.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mito_carr PF00153.27 GAX09499.1 - 2e-19 69.3 0.0 3.5e-08 33.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein HECT_2 PF09814.9 GAX09502.1 - 2.9e-17 62.6 1.7 2.9e-17 62.6 1.7 1.9 2 0 0 2 2 2 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-MYND PF01753.18 GAX09502.1 - 9.3e-08 32.0 23.0 9.3e-08 32.0 23.0 3.0 3 0 0 3 3 3 1 MYND finger Rep_fac-A_3 PF08661.11 GAX09502.1 - 0.1 13.0 0.1 0.3 11.5 0.1 1.8 1 0 0 1 1 1 0 Replication factor A protein 3 Ecl1 PF12855.7 GAX09502.1 - 0.46 11.6 10.8 1.2 10.3 10.8 1.7 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Mpv17_PMP22 PF04117.12 GAX09503.1 - 2.1e-14 53.5 3.4 4.5e-14 52.4 3.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family APOBEC1 PF18769.1 GAX09503.1 - 0.018 15.3 0.1 0.051 13.8 0.1 1.8 1 0 0 1 1 1 0 APOBEC1 AKNA PF12443.8 GAX09503.1 - 0.071 13.8 0.2 0.14 12.9 0.2 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor IMS PF00817.20 GAX09505.1 - 2.1e-20 73.3 0.0 1.8e-19 70.2 0.0 2.6 2 2 0 2 2 2 1 impB/mucB/samB family Phage_1_1 PF08200.11 GAX09505.1 - 0.025 15.0 0.5 13 6.3 0.2 2.8 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein DER1 PF04511.15 GAX09507.1 - 1.4e-38 132.7 9.0 1.6e-38 132.5 9.0 1.0 1 0 0 1 1 1 1 Der1-like family BHD_1 PF10403.9 GAX09508.1 - 2e-14 53.2 0.0 6.3e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 GAX09508.1 - 7.5e-13 48.7 0.0 1.5e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 GAX09508.1 - 1.1e-11 45.5 1.9 6.2e-11 43.1 1.9 2.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 GAX09508.1 - 0.00017 21.3 2.6 0.00068 19.3 2.6 1.9 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain APOC4 PF15119.6 GAX09508.1 - 0.0042 17.3 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 Apolipoprotein C4 Transglut_core PF01841.19 GAX09508.1 - 0.019 15.4 0.2 0.17 12.3 0.0 2.6 3 0 0 3 3 3 0 Transglutaminase-like superfamily Myb_DNA-binding PF00249.31 GAX09509.1 - 0.022 15.0 0.1 0.25 11.6 0.0 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain Sporozoite_P67 PF05642.11 GAX09509.1 - 0.056 11.5 3.0 0.082 11.0 3.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ELM2 PF01448.24 GAX09509.1 - 0.067 14.0 0.0 0.067 14.0 0.0 2.5 2 0 0 2 2 2 0 ELM2 domain Sigma70_ner PF04546.13 GAX09509.1 - 3.2 7.6 8.8 2.3 8.1 4.2 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region FAM176 PF14851.6 GAX09509.1 - 4.5 6.9 9.8 2.7 7.7 5.5 2.2 2 0 0 2 2 2 0 FAM176 family Pex16 PF08610.10 GAX09511.1 - 3.2e-18 66.0 2.6 6.7e-18 64.9 2.6 1.4 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Orn_Arg_deC_N PF02784.16 GAX09512.1 - 1.7e-25 89.9 0.0 2.4e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAX09512.1 - 5.5e-14 52.2 0.0 6.8e-14 51.9 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CTP_transf_1 PF01148.20 GAX09513.1 - 4.6e-48 164.3 14.7 7.1e-48 163.7 14.7 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family MFS_1 PF07690.16 GAX09514.1 - 2.6e-28 99.0 27.9 2.4e-19 69.5 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4181 PF13789.6 GAX09514.1 - 0.46 10.8 2.2 2 8.7 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Flavodoxin_1 PF00258.25 GAX09517.1 - 2.8e-21 76.2 0.9 2.8e-21 76.2 0.9 1.5 2 0 0 2 2 2 1 Flavodoxin DUF2922 PF11148.8 GAX09517.1 - 0.0081 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2922) Flavodoxin_5 PF12724.7 GAX09517.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin domain FMN_red PF03358.15 GAX09517.1 - 0.085 12.6 0.0 0.4 10.4 0.0 2.2 2 1 0 2 2 2 0 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 GAX09518.1 - 4.9e-22 78.7 0.3 5.9e-22 78.4 0.3 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 GAX09518.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin domain Flavodoxin_3 PF12641.7 GAX09518.1 - 0.041 13.6 0.0 0.79 9.4 0.0 2.5 1 1 0 1 1 1 0 Flavodoxin domain FMN_red PF03358.15 GAX09518.1 - 0.058 13.1 0.0 0.3 10.8 0.0 2.3 1 1 0 1 1 1 0 NADPH-dependent FMN reductase LEM PF03020.15 GAX09518.1 - 0.098 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 LEM domain FKBP_C PF00254.28 GAX09519.1 - 0.00029 21.1 0.0 0.00056 20.2 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Fis1_TPR_C PF14853.6 GAX09519.1 - 0.013 15.6 0.8 0.047 13.8 0.2 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 GAX09519.1 - 0.25 12.2 5.3 0.83 10.6 0.6 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX09519.1 - 0.89 10.1 9.2 21 5.7 3.9 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_64 PF09258.10 GAX09520.1 - 1.2e-11 44.4 0.0 2.4e-07 30.3 0.0 2.4 3 0 0 3 3 3 2 Glycosyl transferase family 64 domain TPT PF03151.16 GAX09522.1 - 1.9e-83 280.2 11.9 2.2e-83 280.0 11.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX09522.1 - 5.9e-06 26.5 28.1 0.00021 21.5 13.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family Ost5 PF05251.12 GAX09522.1 - 0.32 11.3 0.0 0.32 11.3 0.0 4.4 5 2 0 5 5 5 0 Oligosaccharyltransferase subunit 5 Tudor_3 PF18115.1 GAX09523.1 - 0.11 12.4 0.3 9.5 6.2 0.2 2.5 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain MUG113 PF13455.6 GAX09523.1 - 0.12 13.1 0.0 0.33 11.6 0.0 1.8 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 p450 PF00067.22 GAX09524.1 - 6e-70 236.3 0.1 7.8e-70 235.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 FliJ PF02050.16 GAX09524.1 - 0.14 12.4 0.2 0.37 11.0 0.2 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Ccdc124 PF06244.12 GAX09525.1 - 3.6e-18 66.4 25.3 3.2e-15 56.8 25.3 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 WD40 PF00400.32 GAX09526.1 - 1.1e-08 35.5 11.1 0.004 18.0 0.5 5.7 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX09526.1 - 0.007 16.6 1.5 0.54 10.6 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX09526.1 - 0.0096 16.4 1.2 0.25 11.9 0.3 3.3 3 1 0 3 3 3 1 PQQ-like domain CBP_BcsG PF11658.8 GAX09526.1 - 0.13 10.6 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Utp8 PF10395.9 GAX09526.1 - 0.21 10.1 0.0 0.42 9.1 0.0 1.4 2 0 0 2 2 2 0 Utp8 family HEAT PF02985.22 GAX09527.1 - 9.5e-08 31.7 4.2 0.53 10.7 0.0 6.1 5 0 0 5 5 5 3 HEAT repeat UNC45-central PF11701.8 GAX09527.1 - 1.6e-06 28.2 4.9 0.11 12.5 0.0 4.6 3 2 1 4 4 4 3 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 GAX09527.1 - 6.2e-06 26.5 10.6 0.01 16.2 1.3 5.3 2 2 3 5 5 5 3 HEAT repeats Cnd1 PF12717.7 GAX09527.1 - 5.1e-05 23.4 3.7 0.24 11.4 0.7 3.3 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAX09527.1 - 0.00067 19.6 9.8 0.27 11.3 0.1 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAX09527.1 - 0.062 13.8 6.0 10 6.7 0.2 4.9 4 2 2 6 6 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAX09527.1 - 0.11 13.1 0.7 0.53 10.9 0.1 2.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 GAX09527.1 - 0.53 10.3 3.9 8 6.6 0.0 4.1 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Peptidase_C71 PF12386.8 GAX09528.1 - 0.12 12.0 0.0 0.85 9.3 0.0 2.0 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei 7tm_3 PF00003.22 GAX09529.1 - 1.1e-27 97.3 16.4 1.5e-27 96.9 16.4 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CcmD PF04995.14 GAX09529.1 - 8.3 6.6 8.1 17 5.6 0.0 3.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) NAD_binding_8 PF13450.6 GAX09530.1 - 2.9e-10 40.2 0.7 9.2e-10 38.6 0.7 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX09530.1 - 2.4e-07 30.7 0.1 1.5e-06 28.0 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAX09530.1 - 2.6e-06 27.0 0.3 2.8e-05 23.6 0.2 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 GAX09530.1 - 0.0047 16.9 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GAX09530.1 - 0.0093 15.3 0.3 0.015 14.6 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 GAX09530.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX09530.1 - 0.02 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAX09530.1 - 0.037 12.9 0.7 0.056 12.3 0.7 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Peptidase_M20 PF01546.28 GAX09531.1 - 3.3e-34 118.4 0.0 4.8e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAX09531.1 - 4.5e-11 42.6 0.0 1.3e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain PRTase_2 PF15609.6 GAX09531.1 - 0.054 13.0 1.4 0.097 12.2 0.8 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase YccV-like PF08755.11 GAX09532.1 - 1e-28 99.7 1.8 3.2e-14 53.2 0.1 2.5 2 0 0 2 2 2 2 Hemimethylated DNA-binding protein YccV like TPR_2 PF07719.17 GAX09532.1 - 1.1e-12 47.0 0.1 0.00034 20.5 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX09532.1 - 6.7e-12 44.7 0.0 0.00013 21.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX09532.1 - 1.6e-07 31.8 0.0 6.4e-05 23.5 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX09532.1 - 4.8e-06 26.8 0.4 0.00073 19.8 0.0 3.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX09532.1 - 9.9e-06 25.4 0.1 0.078 13.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX09532.1 - 1.5e-05 25.0 0.0 0.025 15.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX09532.1 - 2.5e-05 24.7 0.6 0.0016 18.9 0.0 3.4 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX09532.1 - 4.7e-05 23.9 0.4 0.084 13.7 0.3 4.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX09532.1 - 7.7e-05 22.4 0.0 0.12 12.5 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX09532.1 - 0.00025 20.7 0.0 1.9 8.3 0.0 3.7 3 1 1 4 4 4 2 TPR repeat TPR_6 PF13174.6 GAX09532.1 - 0.0012 19.3 0.5 0.6 10.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3458_C PF17432.2 GAX09532.1 - 0.035 13.5 0.5 0.084 12.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats TPR_9 PF13371.6 GAX09532.1 - 0.07 13.3 0.0 0.66 10.2 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat HLH PF00010.26 GAX09532.1 - 0.091 12.7 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain TPR_20 PF14561.6 GAX09532.1 - 0.13 12.6 1.4 0.54 10.6 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX09532.1 - 0.19 12.0 0.4 6.9 7.0 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TB PF00683.17 GAX09533.1 - 7.8 6.3 11.4 6.4 6.6 0.0 4.2 4 0 0 4 4 4 0 TB domain Methyltransf_16 PF10294.9 GAX09534.1 - 8.8e-06 25.6 0.0 5.7e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAX09534.1 - 0.00013 21.8 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX09534.1 - 0.00067 19.5 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAX09534.1 - 0.0019 18.8 0.0 0.011 16.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX09534.1 - 0.015 16.0 0.0 0.086 13.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 GAX09534.1 - 0.025 14.1 0.0 0.076 12.5 0.0 1.7 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 GAX09534.1 - 0.07 13.9 0.0 0.54 11.0 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Phage_ABA_S PF18066.1 GAX09535.1 - 0.0083 16.8 1.8 1.4 9.6 0.1 3.7 2 1 1 3 3 3 2 Phage ABA sandwich domain DUF285 PF03382.14 GAX09538.1 - 7.4e-105 345.3 55.8 7.6e-31 106.4 5.6 4.9 1 1 4 5 5 5 5 Mycoplasma protein of unknown function, DUF285 DrrA_P4M PF14860.6 GAX09538.1 - 0.72 9.7 3.0 11 5.9 0.2 3.4 2 1 2 4 4 4 0 DrrA phosphatidylinositol 4-phosphate binding domain MBOAT_2 PF13813.6 GAX09539.1 - 6.7e-09 35.9 4.4 6.7e-09 35.9 4.4 2.4 4 0 0 4 4 4 1 Membrane bound O-acyl transferase family MutS_V PF00488.21 GAX09541.1 - 1.1e-58 198.4 0.0 2.6e-58 197.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAX09541.1 - 3.2e-28 99.3 1.2 7.5e-28 98.1 1.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAX09541.1 - 3.7e-05 24.0 0.0 0.00013 22.2 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 GAX09541.1 - 0.0035 17.9 0.1 0.0074 16.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX09541.1 - 0.026 14.2 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX09541.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 GAX09541.1 - 0.075 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 GAX09541.1 - 0.094 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX09541.1 - 0.1 13.1 0.0 0.38 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter TAXi_N PF14543.6 GAX09542.1 - 4e-18 66.3 7.4 4e-18 66.3 7.4 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX09542.1 - 6.5e-15 55.3 0.1 1.5e-13 50.9 0.1 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Peptidase_M1 PF01433.20 GAX09543.1 - 1.2e-83 280.0 0.8 2.6e-83 278.9 0.4 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAX09543.1 - 2e-74 250.9 0.0 9.4e-74 248.8 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAX09543.1 - 6.8e-46 156.8 0.1 1.1e-45 156.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain TFIIS_C PF01096.18 GAX09544.1 - 7.1e-22 77.0 3.1 7.1e-22 77.0 3.1 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 GAX09544.1 - 2.5e-05 24.2 4.8 0.00015 21.7 1.2 2.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.16 GAX09544.1 - 0.00019 21.2 4.9 0.00026 20.8 0.4 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 GAX09544.1 - 0.0009 18.9 2.0 0.0009 18.9 2.0 1.8 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_10 PF10058.9 GAX09544.1 - 0.031 14.0 3.9 0.1 12.3 1.3 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 GAX09544.1 - 0.22 11.5 9.7 0.27 11.2 3.4 3.1 2 2 1 3 3 3 0 PhnA Zinc-Ribbon zf-piccolo PF05715.13 GAX09544.1 - 0.27 11.4 6.0 0.33 11.1 0.2 2.6 2 2 0 2 2 2 0 Piccolo Zn-finger DUF4734 PF15881.5 GAX09544.1 - 0.72 10.1 6.4 5.7 7.2 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4734) TF_Zn_Ribbon PF08271.12 GAX09544.1 - 7.7 6.1 9.3 10 5.7 1.2 2.9 2 1 1 3 3 3 0 TFIIB zinc-binding Cupin_8 PF13621.6 GAX09545.1 - 4.4e-21 75.7 0.1 6.8e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX09545.1 - 0.0001 21.9 0.0 0.0004 20.0 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein DUF2157 PF09925.9 GAX09545.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DAO PF01266.24 GAX09546.1 - 3.7e-28 99.1 0.1 5.9e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX09546.1 - 9.9e-07 28.3 0.0 0.0024 17.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX09546.1 - 1.3e-05 25.2 0.4 0.012 15.6 0.2 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 GAX09546.1 - 0.00019 20.6 0.0 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAX09546.1 - 0.0022 17.1 0.0 0.006 15.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 GAX09546.1 - 0.0058 15.7 0.6 1.3 8.0 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein ThiF PF00899.21 GAX09546.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 GAX09546.1 - 0.013 15.8 0.1 0.33 11.2 0.0 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 GAX09546.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAX09546.1 - 0.047 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 GAX09546.1 - 0.071 12.8 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 GAX09546.1 - 0.078 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YCII PF03795.14 GAX09547.1 - 8.8e-09 35.7 0.0 1.4e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain EIAV_Rev PF11129.8 GAX09548.1 - 0.043 14.0 0.3 0.07 13.3 0.3 1.3 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus PVL_ORF50 PF07768.11 GAX09548.1 - 0.41 11.0 7.5 11 6.3 0.1 2.4 2 0 0 2 2 2 0 PVL ORF-50-like family DnaJ-X PF14308.6 GAX09549.1 - 3.8e-30 104.9 8.9 6.5e-30 104.1 8.9 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAX09549.1 - 1.3e-21 76.5 2.7 3.1e-21 75.3 2.7 1.7 1 0 0 1 1 1 1 DnaJ domain SurA_N_2 PF13623.6 GAX09550.1 - 0.014 15.3 0.2 0.035 14.0 0.2 1.6 1 0 0 1 1 1 0 SurA N-terminal domain DUF4381 PF14316.6 GAX09550.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) HMG_box_2 PF09011.10 GAX09551.1 - 1.2e-10 41.8 4.4 2.9e-10 40.6 4.4 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 GAX09551.1 - 1.4e-10 41.4 8.9 1.7e-09 37.9 8.9 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box Gag_p24 PF00607.20 GAX09551.1 - 1.1 9.1 5.3 0.32 10.8 2.2 1.6 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Thioredoxin PF00085.20 GAX09552.1 - 4.5e-21 74.8 0.0 1e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX09552.1 - 6.8e-08 32.7 1.8 0.013 15.8 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX09552.1 - 2.2e-06 28.1 3.1 5.2e-06 26.9 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAX09552.1 - 2.6e-06 27.3 0.6 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GAX09552.1 - 9.9e-05 22.1 0.2 0.00022 21.0 0.1 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 GAX09552.1 - 0.0013 18.9 0.1 0.0061 16.7 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAX09552.1 - 0.0025 17.8 0.3 0.0099 15.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin domain DUF4600 PF15372.6 GAX09552.1 - 0.0061 17.0 3.8 0.0081 16.6 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) Glutaredoxin PF00462.24 GAX09552.1 - 0.04 14.1 0.3 0.14 12.4 0.3 1.9 1 1 0 1 1 1 0 Glutaredoxin TraF PF13728.6 GAX09552.1 - 0.043 13.6 0.4 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 GAX09552.1 - 0.64 10.2 4.7 11 6.2 4.7 2.6 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 GAX09553.1 - 2.2e-50 168.9 0.0 7.4e-25 87.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 GAX09553.1 - 1e-17 64.0 0.0 7.1e-08 32.4 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin AhpC-TSA PF00578.21 GAX09553.1 - 3.6e-14 52.7 0.0 4.4e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.6 GAX09553.1 - 2e-13 50.7 0.0 3.8e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Redoxin PF08534.10 GAX09553.1 - 1.6e-12 47.4 0.0 7.3e-06 25.8 0.0 2.6 2 1 0 2 2 2 2 Redoxin Thioredoxin_7 PF13899.6 GAX09553.1 - 1.4e-09 38.0 1.3 0.00017 21.7 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like TraF PF13728.6 GAX09553.1 - 6.5e-09 35.9 0.2 0.00088 19.2 0.0 3.4 3 1 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GAX09553.1 - 2.3e-06 27.4 0.0 0.053 13.3 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 GAX09553.1 - 1.9e-05 24.6 0.0 5.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain SCO1-SenC PF02630.14 GAX09553.1 - 7.8e-05 22.6 0.1 0.0009 19.2 0.0 2.2 2 0 0 2 2 2 1 SCO1/SenC NADH_4Fe-4S PF10589.9 GAX09553.1 - 0.0034 17.4 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ARL17 PF15840.5 GAX09553.1 - 0.084 13.3 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 Glutaredoxin PF00462.24 GAX09553.1 - 0.18 12.1 4.0 10 6.4 0.2 3.6 3 1 0 3 3 3 0 Glutaredoxin PUB PF09409.10 GAX09554.1 - 3.7e-05 23.6 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PUB domain CDPS PF16715.5 GAX09554.1 - 0.024 14.3 0.7 0.042 13.5 0.7 1.4 1 0 0 1 1 1 0 Cyclodipeptide synthase NB-ARC PF00931.22 GAX09554.1 - 0.057 12.6 0.1 0.095 11.9 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain CEND1 PF15677.5 GAX09554.1 - 0.2 12.2 2.8 0.28 11.7 2.8 1.2 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 cobW PF02492.19 GAX09555.1 - 9.1e-28 97.0 0.1 1.1e-27 96.7 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 GAX09555.1 - 0.00011 21.3 0.1 0.0078 15.2 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 GAX09555.1 - 0.0096 16.0 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 GAX09555.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 GAX09555.1 - 0.031 14.3 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAX09555.1 - 0.032 14.6 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 GAX09555.1 - 0.036 13.8 0.0 0.061 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX09555.1 - 0.038 14.5 0.0 0.047 14.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 GAX09555.1 - 0.055 14.0 0.0 0.093 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAX09555.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GAX09555.1 - 0.19 10.8 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Amidohydro_1 PF01979.20 GAX09556.1 - 1.3e-72 245.1 0.3 2e-72 244.4 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 GAX09556.1 - 4.8e-53 178.6 5.1 1e-52 177.6 5.1 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 GAX09556.1 - 6.1e-39 132.3 0.1 1.6e-38 131.0 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 GAX09556.1 - 4.4e-34 116.4 0.0 3.2e-33 113.7 0.0 2.2 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 GAX09556.1 - 2.8e-08 33.7 0.4 3.9e-06 26.6 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase family DUF1275 PF06912.11 GAX09557.1 - 4.2e-13 49.6 16.5 6e-13 49.1 16.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) ParE-like_toxin PF15781.5 GAX09558.1 - 0.098 12.6 0.1 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system BRAP2 PF07576.12 GAX09558.1 - 0.19 12.0 1.1 0.68 10.2 1.1 1.9 1 1 0 1 1 1 0 BRCA1-associated protein 2 Dynamin_N PF00350.23 GAX09559.1 - 1.6e-11 44.6 0.2 1.3e-09 38.4 0.0 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAX09559.1 - 0.0051 16.9 0.0 0.032 14.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 GAX09559.1 - 0.21 11.7 1.3 2.5 8.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 GAX09559.1 - 0.23 11.1 6.4 5.7 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Trp_oprn_chp PF09534.10 GAX09561.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cys_Met_Meta_PP PF01053.20 GAX09562.1 - 4.3e-83 279.0 0.0 5.8e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAX09562.1 - 0.068 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF5300 PF17224.3 GAX09563.1 - 1.2 9.5 9.4 0.036 14.3 1.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5300) Acid_PPase PF12689.7 GAX09564.1 - 2.5e-42 144.6 0.0 2.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase DUF2608 PF11019.8 GAX09564.1 - 0.18 11.3 0.0 0.56 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Abhydrolase_6 PF12697.7 GAX09565.1 - 2.7e-14 54.3 0.5 3.3e-14 54.0 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX09565.1 - 2.9e-12 46.8 0.0 1.1e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX09565.1 - 1e-08 34.8 0.0 1.3e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 GAX09565.1 - 0.00058 19.5 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase BAAT_C PF08840.11 GAX09565.1 - 0.016 15.2 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 GAX09565.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 GAX09565.1 - 0.066 12.8 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 GAX09565.1 - 0.17 11.7 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold PqiA PF04403.13 GAX09566.1 - 7.8e-05 22.5 19.3 0.0084 15.9 7.0 2.6 2 0 0 2 2 2 2 Paraquat-inducible protein A Cyclin_N PF00134.23 GAX09567.1 - 5.3e-29 100.5 0.3 5.5e-28 97.3 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX09567.1 - 4.4e-22 78.4 0.2 8.9e-22 77.4 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain 2OG-FeII_Oxy PF03171.20 GAX09568.1 - 4.2e-14 52.9 0.0 1.2e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TIM PF00121.18 GAX09569.1 - 9e-82 274.1 0.0 1.1e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase YtxH PF12732.7 GAX09570.1 - 0.0009 19.7 14.0 3.5 8.2 0.9 3.9 1 1 1 2 2 2 1 YtxH-like protein DUF1018 PF06252.12 GAX09570.1 - 0.033 15.2 0.6 0.033 15.2 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1018) ISG65-75 PF11727.8 GAX09570.1 - 0.095 11.9 13.7 0.017 14.3 3.3 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein Apolipoprotein PF01442.18 GAX09570.1 - 0.1 12.4 9.9 0.24 11.2 7.9 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1359 PF07097.11 GAX09570.1 - 0.22 11.8 1.8 4.1 7.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) DUF4554 PF15091.6 GAX09570.1 - 1.3 7.9 7.2 0.15 10.9 2.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4554) Lipoprotein_2 PF00921.17 GAX09570.1 - 1.8 8.1 10.1 1.3 8.5 7.6 1.9 1 1 0 2 2 2 0 Borrelia lipoprotein REV1_C PF16727.5 GAX09570.1 - 7.4 7.0 9.5 1.4e+02 2.9 9.5 3.0 1 1 0 1 1 1 0 DNA repair protein REV1 C-terminal domain DUF3994 PF13159.6 GAX09570.1 - 9.2 6.9 9.6 24 5.6 3.0 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF3994) CBS PF00571.28 GAX09571.1 - 3e-25 88.4 0.8 3.8e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 CBS domain Peptidase_S29 PF02907.15 GAX09571.1 - 0.0007 19.4 0.1 0.0016 18.2 0.0 1.6 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Trypsin_2 PF13365.6 GAX09571.1 - 0.0049 17.8 0.0 0.011 16.7 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.21 GAX09571.1 - 0.14 12.0 0.0 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease sCache_3_3 PF17202.4 GAX09571.1 - 0.17 12.3 0.0 9 6.8 0.1 2.5 3 0 0 3 3 3 0 Single cache domain 3 polyprenyl_synt PF00348.17 GAX09572.1 - 2.9e-66 223.2 0.0 4e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 GAX09572.1 - 0.0021 17.7 0.1 0.0038 16.9 0.1 1.4 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Glyco_transf_28 PF03033.20 GAX09573.1 - 2.9e-18 66.2 0.0 6.8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAX09573.1 - 0.00066 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAX09573.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RTX PF02382.15 GAX09573.1 - 0.21 11.3 0.5 0.57 9.8 0.1 1.7 2 0 0 2 2 2 0 N-terminal domain in RTX protein SET PF00856.28 GAX09574.1 - 2.7e-11 44.1 0.0 0.0005 20.5 0.0 4.1 2 2 0 2 2 2 2 SET domain DUF1539 PF07560.11 GAX09574.1 - 0.062 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DivIVA PF05103.13 GAX09575.1 - 0.41 10.7 6.5 0.57 10.3 6.2 1.4 1 1 0 1 1 1 0 DivIVA protein ZapB PF06005.12 GAX09575.1 - 0.44 11.0 9.5 1.6 9.2 9.5 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DUF1043 PF06295.12 GAX09575.1 - 0.86 9.6 5.3 0.41 10.6 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) MerR-DNA-bind PF09278.11 GAX09575.1 - 2.1 8.9 7.0 1.7 9.2 0.5 2.5 1 1 1 2 2 2 0 MerR, DNA binding DivIC PF04977.15 GAX09575.1 - 2.9 7.7 6.4 2.9 7.7 2.1 2.7 2 1 1 3 3 3 0 Septum formation initiator FlaC_arch PF05377.11 GAX09575.1 - 3.8 8.0 8.5 4.4 7.8 0.6 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Rab3-GTPase_cat PF13890.6 GAX09576.1 - 5e-38 130.3 0.3 1.4e-37 128.9 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit Methyltransf_32 PF13679.6 GAX09578.1 - 1.4e-06 28.4 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Glycos_transf_3 PF00591.21 GAX09579.1 - 1.3e-86 290.3 0.2 1.9e-86 289.8 0.0 1.3 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 GAX09579.1 - 1.4e-17 63.3 0.2 4.1e-17 61.8 0.2 1.9 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain LRR_4 PF12799.7 GAX09580.1 - 0.00011 22.5 1.3 2.9 8.4 0.1 4.1 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX09580.1 - 0.012 16.0 0.9 99 4.1 0.0 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GAX09580.1 - 0.097 12.8 1.2 1.6e+02 2.7 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat EF-hand_1 PF00036.32 GAX09581.1 - 0.00052 19.4 2.8 0.06 12.9 0.0 4.6 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 GAX09581.1 - 1.7 8.8 5.4 1.4 9.1 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain NCD1 PF04904.13 GAX09583.1 - 0.15 12.1 0.1 0.5 10.4 0.0 1.8 1 1 1 2 2 2 0 NAB conserved region 1 (NCD1) WXG100 PF06013.12 GAX09583.1 - 0.24 11.6 1.9 4.8 7.5 0.3 2.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG YjgF_endoribonc PF14588.6 GAX09584.1 - 3.6e-28 98.6 0.0 4.5e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 GAX09584.1 - 1.8e-17 63.5 0.0 2.4e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP PT PF04886.12 GAX09585.1 - 0.00043 19.8 15.3 0.00043 19.8 15.3 3.5 2 1 1 3 3 3 1 PT repeat PDZ_6 PF17820.1 GAX09585.1 - 0.029 14.2 0.1 0.08 12.8 0.1 1.8 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 GAX09585.1 - 0.05 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 PDZ domain DUF4131 PF13567.6 GAX09585.1 - 0.1 12.2 0.0 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Alpha_kinase PF02816.18 GAX09586.1 - 3.1e-32 112.2 1.8 6.6e-18 65.5 0.7 2.4 2 0 0 2 2 2 2 Alpha-kinase family Ribosomal_L37ae PF01780.19 GAX09586.1 - 1.8 8.7 4.4 32 4.7 0.1 2.9 3 0 0 3 3 3 0 Ribosomal L37ae protein family PDZ PF00595.24 GAX09587.1 - 4.1e-05 23.8 1.2 9.9e-05 22.6 1.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX09587.1 - 0.00034 20.9 1.2 0.00078 19.7 1.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX09587.1 - 0.0063 16.3 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX09588.1 - 2.6e-05 24.5 0.1 4.9e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX09588.1 - 0.00024 21.4 0.2 0.00058 20.1 0.1 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX09588.1 - 0.00053 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Autophagy_C PF10381.9 GAX09588.1 - 0.13 11.8 0.4 0.33 10.5 0.4 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal HATPase_c PF02518.26 GAX09589.1 - 1.9e-08 34.8 0.0 3.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX09589.1 - 0.00093 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAX09589.1 - 0.16 12.0 0.0 0.5 10.3 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain PDZ PF00595.24 GAX09590.1 - 1e-05 25.8 2.3 1.3e-05 25.5 0.9 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX09590.1 - 0.0003 20.6 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX09590.1 - 0.0034 17.7 0.6 0.0091 16.3 0.6 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_4 PF17816.1 GAX09590.1 - 0.16 12.4 0.3 0.38 11.2 0.2 1.7 1 1 0 1 1 1 0 PDZ domain Ni_hydr_CYTB PF01292.20 GAX09590.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 ATP-synt_C PF00137.21 GAX09591.1 - 1.5e-34 118.2 37.3 5.4e-23 81.1 16.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C RRM_1 PF00076.22 GAX09592.1 - 3.2e-17 62.1 3.0 1.3e-12 47.4 0.3 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAX09592.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 GAX09592.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain TAXi_N PF14543.6 GAX09593.1 - 0.09 13.0 0.4 0.22 11.7 0.4 1.6 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal PseudoU_synth_2 PF00849.22 GAX09594.1 - 6.4e-25 88.1 2.6 4.6e-23 82.1 2.6 2.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase MIT_C PF16565.5 GAX09595.1 - 0.42 10.6 2.4 1.2 9.1 0.4 2.4 2 0 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT ABC_tran PF00005.27 GAX09596.1 - 2.4e-51 173.9 0.1 2.6e-24 86.3 0.1 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAX09596.1 - 1.4e-16 61.2 8.9 0.00013 21.9 0.0 4.7 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX09596.1 - 1.8e-12 47.2 5.9 7e-06 25.6 0.5 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 GAX09596.1 - 1e-10 41.5 4.3 1.5e-09 37.7 0.7 2.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 GAX09596.1 - 2.7e-07 30.2 1.7 0.0016 18.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX09596.1 - 1.4e-06 29.0 2.4 0.015 15.8 0.1 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAX09596.1 - 1.2e-05 25.3 0.2 0.085 12.9 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 GAX09596.1 - 2.6e-05 24.4 1.1 0.088 13.0 0.1 3.0 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 GAX09596.1 - 9.5e-05 22.5 3.1 0.0075 16.3 0.1 2.7 2 1 0 2 2 2 1 Dynamin family MeaB PF03308.16 GAX09596.1 - 0.00013 21.1 0.2 0.25 10.3 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 GAX09596.1 - 0.00015 21.7 0.6 0.017 15.0 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 GAX09596.1 - 0.0002 21.9 0.3 0.88 10.1 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX09596.1 - 0.00023 21.4 8.4 0.0062 16.8 0.2 4.2 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GAX09596.1 - 0.00028 20.7 1.5 0.19 11.4 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 GAX09596.1 - 0.00037 20.5 0.1 2.2 8.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 GAX09596.1 - 0.0011 18.7 0.3 2.1 8.0 0.2 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 GAX09596.1 - 0.0022 18.2 0.8 4.2 7.7 0.0 4.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 GAX09596.1 - 0.0025 17.0 1.9 0.45 9.7 0.1 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 GAX09596.1 - 0.0037 17.7 5.2 0.24 11.8 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 GAX09596.1 - 0.0038 17.0 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 GAX09596.1 - 0.0038 17.7 0.2 0.55 10.6 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAX09596.1 - 0.0041 17.4 0.2 0.71 10.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX09596.1 - 0.0057 16.4 0.2 2.7 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAX09596.1 - 0.014 15.8 1.3 5.1 7.5 0.1 3.0 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 GAX09596.1 - 0.018 14.9 0.2 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 GAX09596.1 - 0.019 15.2 0.9 4.7 7.4 0.1 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Adeno_IVa2 PF02456.15 GAX09596.1 - 0.026 13.3 0.2 0.086 11.6 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein cobW PF02492.19 GAX09596.1 - 0.027 14.0 5.6 0.39 10.3 0.2 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 GAX09596.1 - 0.036 13.5 0.3 5.4 6.4 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF815 PF05673.13 GAX09596.1 - 0.052 12.7 0.1 0.92 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 GAX09596.1 - 0.056 13.0 0.0 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAX09596.1 - 0.073 13.0 0.3 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Spore_IV_A PF09547.10 GAX09596.1 - 0.077 11.9 0.1 4 6.3 0.0 2.2 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) RNA_helicase PF00910.22 GAX09596.1 - 0.077 13.4 0.0 5.9 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 GAX09596.1 - 0.11 12.5 2.5 6.3 6.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Septin PF00735.18 GAX09596.1 - 0.12 11.6 0.4 1.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Septin AAA_19 PF13245.6 GAX09596.1 - 0.14 12.5 0.6 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 GAX09596.1 - 0.15 11.2 0.2 4.8 6.2 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_13 PF13166.6 GAX09596.1 - 0.16 10.6 4.0 11 4.5 0.1 3.7 3 1 1 4 4 4 0 AAA domain T2SSE PF00437.20 GAX09596.1 - 0.19 10.8 0.1 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 GAX09596.1 - 0.19 11.1 0.9 50 3.2 0.1 3.4 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 GAX09596.1 - 0.37 10.8 6.0 12 5.9 0.2 3.8 4 0 0 4 4 3 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 GAX09596.1 - 0.67 9.3 2.4 17 4.6 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family dNK PF01712.19 GAX09596.1 - 1.3 8.8 3.4 26 4.6 0.2 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase SNF2_N PF00176.23 GAX09597.1 - 4.7e-38 130.8 0.1 8.7e-38 129.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX09597.1 - 8.2e-18 64.8 0.0 3.2e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX09597.1 - 6.8e-05 22.9 1.5 0.00078 19.5 0.1 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HTH_31 PF13560.6 GAX09597.1 - 0.037 14.4 0.7 0.1 13.0 0.7 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ERCC3_RAD25_C PF16203.5 GAX09597.1 - 0.049 12.8 0.0 0.15 11.2 0.0 1.8 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 GAX09597.1 - 0.066 13.4 0.3 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain Glyco_tran_WecB PF03808.13 GAX09597.1 - 0.14 12.1 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family SET PF00856.28 GAX09598.1 - 1.3e-16 61.5 2.8 2.2e-16 60.7 0.1 2.7 2 2 0 2 2 2 1 SET domain PHD PF00628.29 GAX09598.1 - 1.5e-07 31.2 36.0 0.0002 21.2 5.2 5.4 4 1 1 5 5 5 4 PHD-finger FANCL_C PF11793.8 GAX09598.1 - 0.0053 16.9 3.2 0.0053 16.9 3.2 3.7 4 0 0 4 4 4 1 FANCL C-terminal domain AWS PF17907.1 GAX09598.1 - 0.0068 16.4 7.5 0.0068 16.4 7.5 4.1 4 1 0 4 4 4 1 AWS domain PHD_2 PF13831.6 GAX09598.1 - 0.007 15.9 1.2 0.007 15.9 1.2 5.4 5 0 0 5 5 5 2 PHD-finger zf-HC5HC2H PF13771.6 GAX09598.1 - 0.009 16.2 25.8 0.029 14.6 3.9 4.2 1 1 2 3 3 3 2 PHD-like zinc-binding domain C1_1 PF00130.22 GAX09598.1 - 0.039 13.9 0.4 0.039 13.9 0.4 5.0 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRM_1 PF00076.22 GAX09599.1 - 0.00054 19.7 0.0 0.0059 16.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIGA PF08288.12 GAX09600.1 - 6.3e-37 126.0 0.9 2.6e-36 124.0 0.1 2.5 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 GAX09600.1 - 2.1e-29 102.7 0.8 3.2e-29 102.1 0.8 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 GAX09600.1 - 5.5e-21 74.8 0.0 9.2e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX09600.1 - 1e-20 74.6 0.0 2.7e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAX09600.1 - 2.6e-13 50.7 0.0 4.2e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX09600.1 - 6.6e-06 26.4 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GAX09600.1 - 0.069 12.8 0.1 0.34 10.6 0.0 1.9 1 1 0 2 2 2 0 Starch synthase catalytic domain NDK PF00334.19 GAX09601.1 - 2.9e-50 169.8 0.0 4e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase COG7 PF10191.9 GAX09602.1 - 6.7e-47 160.2 3.2 7.8e-39 133.5 4.9 2.0 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) baeRF_family6 PF18848.1 GAX09602.1 - 0.033 14.6 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 Spectrin PF00435.21 GAX09602.1 - 0.42 11.1 6.1 15 6.1 0.1 3.9 4 1 0 4 4 4 0 Spectrin repeat Syja_N PF02383.18 GAX09603.1 - 2.4e-54 184.8 0.0 6.4e-54 183.4 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain Rieske PF00355.26 GAX09603.1 - 0.16 11.9 0.0 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain DUF4011 PF13195.6 GAX09604.1 - 0.026 14.4 0.2 0.08 12.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Mito_carr PF00153.27 GAX09605.1 - 1.6e-42 143.3 3.2 3.6e-15 55.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 GAX09605.1 - 0.012 16.0 4.5 0.11 12.9 2.9 2.6 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Aminotran_1_2 PF00155.21 GAX09606.1 - 2.1e-44 152.2 0.0 2.5e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 GAX09606.1 - 0.0058 15.5 0.0 0.016 14.1 0.0 1.6 1 1 0 1 1 1 1 Allinase Beta_elim_lyase PF01212.21 GAX09606.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Glyoxalase_4 PF13669.6 GAX09607.1 - 3e-08 33.9 0.2 0.00062 20.0 0.0 3.0 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 GAX09607.1 - 8.7e-08 32.4 0.0 2.2e-05 24.7 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GAX09607.1 - 4.8e-06 26.8 1.2 0.00077 19.6 0.2 2.9 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 GAX09607.1 - 0.013 15.6 2.1 3.2 7.8 0.3 3.8 2 2 0 2 2 2 0 Glyoxalase-like domain DUF3449 PF11931.8 GAX09607.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Glyco_tranf_2_4 PF13704.6 GAX09608.1 - 0.027 15.0 2.2 0.099 13.2 2.2 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF2767 PF10965.8 GAX09609.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) rve PF00665.26 GAX09610.1 - 0.0005 20.3 0.3 0.0014 18.8 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain TPR_1 PF00515.28 GAX09611.1 - 2.9e-05 23.7 2.8 0.0085 15.9 0.6 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX09611.1 - 4.4e-05 23.3 1.8 0.043 13.9 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX09611.1 - 0.00011 22.2 3.2 0.07 13.4 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX09611.1 - 0.00035 21.0 0.4 5.2 7.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX09611.1 - 0.00039 20.0 1.1 0.08 12.6 0.0 3.0 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 GAX09611.1 - 0.0052 17.0 0.0 5.7 7.2 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAX09611.1 - 0.0059 17.2 3.3 8.1 7.2 0.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX09611.1 - 0.0062 17.3 1.8 4.2 8.4 0.0 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX09611.1 - 0.019 15.3 0.5 0.45 10.9 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX09611.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR TPR_7 PF13176.6 GAX09611.1 - 0.12 12.4 1.9 3.3 8.0 0.4 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat MatP_C PF17414.2 GAX09611.1 - 1.4 9.2 3.7 1.1 9.5 0.3 2.5 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain Presenilin PF01080.17 GAX09612.1 - 3.5e-102 342.2 0.1 7.1e-102 341.1 0.1 1.5 1 1 0 1 1 1 1 Presenilin PPR_2 PF13041.6 GAX09612.1 - 1.3e-12 47.7 0.2 0.00022 21.4 0.0 6.7 8 0 0 8 8 8 2 PPR repeat family PPR PF01535.20 GAX09612.1 - 0.00078 19.5 1.5 0.084 13.2 0.0 4.9 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.7 GAX09612.1 - 0.00094 18.8 3.6 2.4 7.9 0.0 4.9 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 GAX09612.1 - 0.013 15.5 0.7 19 5.4 0.0 5.2 5 1 0 5 5 5 0 Pentatricopeptide repeat domain CC2D2AN-C2 PF15625.6 GAX09613.1 - 0.09 12.5 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain DUF5480 PF17576.2 GAX09613.1 - 0.19 11.7 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5480) PAP_fibrillin PF04755.12 GAX09614.1 - 8.1e-13 48.8 0.6 8.6e-12 45.4 0.6 2.4 1 1 0 1 1 1 1 PAP_fibrillin ABC_tran PF00005.27 GAX09615.1 - 3.2e-30 105.4 0.0 7.7e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX09615.1 - 9.3e-26 91.1 4.9 4.8e-25 88.7 4.9 1.8 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 GAX09615.1 - 3.4e-06 27.1 2.4 0.0091 15.8 1.9 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX09615.1 - 0.00018 21.2 0.1 0.00044 19.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 GAX09615.1 - 0.00029 20.4 0.7 0.0051 16.3 0.1 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX09615.1 - 0.00034 20.4 0.0 0.00073 19.3 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GAX09615.1 - 0.00089 19.8 0.0 0.0024 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAX09615.1 - 0.011 15.6 0.1 0.035 14.0 0.1 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 GAX09615.1 - 0.03 14.7 2.8 0.094 13.1 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GAX09615.1 - 0.11 12.8 0.1 1 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX09615.1 - 0.11 12.7 0.2 0.9 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX09615.1 - 0.11 12.0 0.2 0.79 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX09615.1 - 0.11 13.0 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain HATPase_c PF02518.26 GAX09616.1 - 0.013 16.0 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Transketolase_N PF00456.21 GAX09617.1 - 4e-148 492.8 0.0 9.4e-148 491.6 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAX09617.1 - 2.6e-45 154.3 0.0 5.7e-45 153.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX09617.1 - 1.4e-08 34.6 0.0 5.9e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAX09617.1 - 0.0062 15.8 0.7 0.01 15.0 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Terpene_synth PF01397.21 GAX09617.1 - 0.086 12.5 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain DUF1295 PF06966.12 GAX09618.1 - 2.5e-23 82.8 0.0 5.4e-23 81.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 GAX09618.1 - 2.4e-05 24.7 0.3 0.00013 22.4 0.2 2.3 1 1 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 GAX09618.1 - 0.00019 21.5 0.2 0.00028 20.9 0.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 GAX09618.1 - 0.0039 17.6 0.2 0.027 14.9 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Pkinase PF00069.25 GAX09619.1 - 1.6e-44 152.2 0.0 1.9e-25 89.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09619.1 - 1.3e-17 63.9 0.1 8.2e-15 54.8 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAX09619.1 - 0.032 13.2 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UQ_con PF00179.26 GAX09620.1 - 8.5e-52 174.5 0.0 9.5e-52 174.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX09620.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 GAX09620.1 - 0.025 14.9 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 GAX09620.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain Octopine_DH PF02317.17 GAX09621.1 - 1.1e-32 113.2 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.17 GAX09621.1 - 0.0025 18.4 0.5 0.0096 16.5 0.5 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAX09621.1 - 0.023 14.0 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 GAX09621.1 - 0.068 12.8 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 GAX09622.1 - 9.1e-56 189.0 0.0 1.3e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX09622.1 - 4e-17 62.6 0.0 7.7e-17 61.7 0.0 1.3 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX09622.1 - 2.9e-06 26.6 1.1 7.6e-06 25.3 0.0 1.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX09622.1 - 0.00014 21.1 0.0 0.00034 19.8 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX09622.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein BRO1 PF03097.18 GAX09624.1 - 1.8e-47 162.0 1.1 2e-47 161.9 1.1 1.1 1 0 0 1 1 1 1 BRO1-like domain Cys_rich_FGFR PF00839.17 GAX09624.1 - 0.31 11.2 5.2 1.1 9.5 0.0 3.3 4 0 0 4 4 4 0 Cysteine rich repeat GDP_Man_Dehyd PF16363.5 GAX09625.1 - 1.1e-61 209.1 0.0 3.3e-61 207.5 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX09625.1 - 6.6e-55 186.2 0.0 8.5e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX09625.1 - 4.1e-18 65.4 0.0 6.9e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAX09625.1 - 5.8e-15 55.2 0.0 5.4e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX09625.1 - 2.2e-12 46.7 0.0 2.9e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX09625.1 - 4.2e-09 36.0 0.0 7.8e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 GAX09625.1 - 4.5e-06 26.7 0.0 8.1e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 GAX09625.1 - 0.00015 21.3 0.0 0.0075 15.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GAX09625.1 - 0.00069 19.5 0.0 0.0033 17.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox PF00070.27 GAX09625.1 - 0.016 15.7 0.1 0.032 14.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 GAX09625.1 - 0.035 13.7 0.1 1 8.9 0.2 2.6 2 1 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 GAX09625.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAX09625.1 - 0.12 12.7 0.0 0.42 10.9 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 GAX09625.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_20 PF00982.21 GAX09630.1 - 7e-98 328.4 0.0 1.3e-97 327.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAX09630.1 - 6.9e-29 100.6 0.0 1.5e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase TMF_TATA_bd PF12325.8 GAX09631.1 - 6 7.1 14.5 0.23 11.7 4.6 3.2 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HATPase_c PF02518.26 GAX09632.1 - 8.9e-29 100.3 0.2 1.7e-28 99.3 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX09632.1 - 2.9e-21 75.7 1.5 9.9e-21 74.0 0.3 2.5 2 1 1 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 GAX09632.1 - 4.7e-16 58.6 0.0 1.8e-15 56.7 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Parvo_NS1 PF01057.17 GAX09632.1 - 0.0032 16.6 0.1 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PAS_4 PF08448.10 GAX09632.1 - 0.018 15.2 0.1 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 PAS fold Methyltr_RsmB-F PF01189.17 GAX09632.1 - 0.022 14.4 0.1 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F SUI1 PF01253.22 GAX09633.1 - 8.9e-17 61.4 0.1 2.3e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.18 GAX09633.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain PUA PF01472.20 GAX09633.1 - 0.014 15.4 0.0 0.051 13.5 0.0 2.0 1 1 0 1 1 1 0 PUA domain NAD_binding_1 PF00175.21 GAX09634.1 - 4.3e-22 78.8 0.0 7.8e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX09634.1 - 1.3e-17 63.9 0.0 2.1e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAX09634.1 - 0.027 14.6 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain HSF_DNA-bind PF00447.17 GAX09636.1 - 3.4e-20 72.4 0.1 6.2e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding NAD_binding_8 PF13450.6 GAX09637.1 - 3.8e-11 43.1 0.0 7.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX09637.1 - 5.2e-07 29.2 0.1 7.3e-07 28.7 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX09637.1 - 6.2e-06 25.2 0.0 0.00051 18.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 GAX09637.1 - 4.7e-05 23.1 0.0 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAX09637.1 - 0.0011 18.4 0.0 0.0024 17.2 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAX09637.1 - 0.0015 17.7 0.1 0.0034 16.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAX09637.1 - 0.0041 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAX09637.1 - 0.016 15.7 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX09637.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAX09637.1 - 0.07 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 GAX09637.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 GAX09637.1 - 0.18 10.8 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAX09637.1 - 0.24 11.2 0.1 0.39 10.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 GAX09637.1 - 0.25 10.5 0.0 0.41 9.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PT PF04886.12 GAX09638.1 - 0.0027 17.2 0.4 0.0053 16.3 0.4 1.4 1 0 0 1 1 1 1 PT repeat CxC7 PF18866.1 GAX09638.1 - 0.085 13.0 1.4 0.12 12.6 0.3 1.8 2 0 0 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases Peptidase_C11 PF03415.14 GAX09639.1 - 5.2e-17 62.3 0.0 5.9e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Clostripain family PT PF04886.12 GAX09640.1 - 1.8e-08 33.7 62.5 0.1 12.2 2.4 8.8 7 2 0 7 7 7 7 PT repeat DLH PF01738.18 GAX09641.1 - 5.8e-31 107.7 0.0 8.2e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX09641.1 - 0.00091 18.7 0.0 0.0033 16.9 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1100 PF06500.11 GAX09641.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 GAX09641.1 - 0.027 13.2 0.0 0.067 11.8 0.0 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) MreB_Mbl PF06723.13 GAX09641.1 - 0.071 11.9 0.0 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein CcmD PF04995.14 GAX09641.1 - 0.087 12.9 0.5 0.087 12.9 0.5 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) IBD PF10416.9 GAX09641.1 - 0.18 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD RAP PF08373.10 GAX09643.1 - 4.6e-14 52.2 0.0 1.7e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 RAP domain FAST_1 PF06743.15 GAX09643.1 - 2.8e-10 40.0 0.8 0.13 12.3 0.0 7.5 6 3 2 8 8 8 2 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 GAX09643.1 - 0.0051 17.0 0.5 5.7 7.2 0.0 3.7 3 0 0 3 3 3 1 REase_MTES_1575 HEAT_EZ PF13513.6 GAX09643.1 - 0.039 14.5 6.1 11 6.7 0.2 5.4 4 1 0 4 4 4 0 HEAT-like repeat HMG_box PF00505.19 GAX09644.1 - 7.9e-11 42.2 5.8 4.7e-08 33.3 2.5 2.9 2 1 1 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX09644.1 - 2.3e-07 31.3 4.4 2.4e-05 24.8 1.6 2.6 1 1 1 2 2 2 2 HMG-box domain HEPN_Swt1 PF18731.1 GAX09644.1 - 0.054 13.8 4.1 0.12 12.8 2.3 2.3 2 0 0 2 2 2 0 Swt1-like HEPN HMG_box_5 PF14887.6 GAX09644.1 - 0.067 13.2 2.5 0.078 13.0 0.7 1.9 1 1 1 2 2 2 0 HMG (high mobility group) box 5 AAA_21 PF13304.6 GAX09644.1 - 0.084 12.7 3.6 0.23 11.2 3.6 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system YABBY PF04690.13 GAX09644.1 - 0.11 13.1 2.0 0.12 12.9 0.6 2.1 1 1 0 1 1 1 0 YABBY protein MAGE PF01454.19 GAX09648.1 - 1.3e-24 87.1 0.0 1.9e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 MAGE family GTP_EFTU PF00009.27 GAX09649.1 - 1.2e-34 119.6 0.0 1.8e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 GAX09649.1 - 3.5e-27 94.7 0.0 7e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 GAX09649.1 - 4.5e-21 74.7 0.0 8.5e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX09649.1 - 1.4e-10 41.4 0.1 2.9e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAX09649.1 - 0.00082 19.4 0.0 0.0032 17.5 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 GAX09649.1 - 0.0013 18.3 0.0 0.0048 16.5 0.0 1.8 2 0 0 2 2 2 1 Ras family RF3_C PF16658.5 GAX09649.1 - 0.0055 16.5 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAX09649.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 GAX09649.1 - 0.03 13.8 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 GAX09649.1 - 0.079 13.0 0.1 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Sel1 PF08238.12 GAX09650.1 - 1.7e-14 53.9 22.6 0.0011 19.6 2.0 9.2 9 0 0 9 9 9 5 Sel1 repeat Choline_kinase PF01633.20 GAX09651.1 - 1.2e-46 158.9 0.0 2e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAX09651.1 - 1.6e-12 47.8 0.5 2.4e-12 47.3 0.5 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAX09651.1 - 0.00064 19.1 0.1 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 GAX09651.1 - 0.013 14.9 0.1 0.087 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 GAX09651.1 - 0.039 13.3 0.6 0.082 12.2 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1995 PF09353.10 GAX09652.1 - 1.1e-20 74.6 0.0 1.4e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) PPR_2 PF13041.6 GAX09654.1 - 3.5e-50 168.0 0.0 2.4e-08 34.0 0.0 9.4 7 2 2 9 9 9 8 PPR repeat family PPR_3 PF13812.6 GAX09654.1 - 5.9e-41 138.4 0.0 1.9e-08 34.2 0.0 7.3 5 2 1 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.20 GAX09654.1 - 1.1e-39 131.9 3.0 7e-05 22.8 0.0 11.8 13 0 0 13 13 13 8 PPR repeat PPR_1 PF12854.7 GAX09654.1 - 5.7e-34 115.5 10.4 1.5e-07 31.0 0.0 10.7 10 1 1 11 11 11 7 PPR repeat PPR_long PF17177.4 GAX09654.1 - 5.2e-20 71.7 0.3 5.8e-09 35.6 0.0 5.0 2 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GAX09654.1 - 0.0073 17.0 16.5 0.15 12.9 1.9 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat Gal11_ABD1 PF18535.1 GAX09654.1 - 0.01 15.9 0.3 0.78 9.9 0.0 3.1 3 1 0 3 3 3 0 Gal11 activator-binding domain (ABD1) BTAD PF03704.17 GAX09654.1 - 0.016 15.7 4.9 0.11 12.9 1.1 3.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 GAX09654.1 - 0.2 12.0 1.9 51 4.3 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_C65 PF10275.9 GAX09655.1 - 2.7e-60 203.9 0.0 3.2e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 GAX09655.1 - 0.00052 20.5 0.0 0.051 14.1 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease AMNp_N PF10423.9 GAX09655.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Cadherin_C_2 PF16492.5 GAX09656.1 - 0.039 14.7 0.0 0.34 11.7 0.0 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Candida_ALS_N PF11766.8 GAX09656.1 - 0.065 12.5 0.7 0.25 10.6 0.2 1.9 2 0 0 2 2 2 0 Cell-wall agglutinin N-terminal ligand-sugar binding PT PF04886.12 GAX09658.1 - 1.6e-07 30.8 33.1 0.0019 17.7 1.5 5.9 4 1 1 5 5 5 4 PT repeat CDC45 PF02724.14 GAX09658.1 - 0.093 11.0 0.4 0.13 10.5 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Remorin_C PF03763.13 GAX09659.1 - 0.013 15.3 0.4 0.013 15.3 0.4 2.2 2 0 0 2 2 2 0 Remorin, C-terminal region DUF4284 PF14112.6 GAX09659.1 - 0.053 14.5 0.0 0.081 13.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 22 Complex1_LYR PF05347.15 GAX09660.1 - 0.00014 21.8 0.1 0.00025 21.0 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF924 PF06041.11 GAX09660.1 - 0.11 12.6 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) HSF_DNA-bind PF00447.17 GAX09661.1 - 1.4e-19 70.5 0.2 2.3e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding MFS_1 PF07690.16 GAX09662.1 - 4.1e-31 108.2 23.0 7.9e-31 107.3 23.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 GAX09663.1 - 8.6e-08 32.3 0.7 8.6e-08 32.3 0.7 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX09663.1 - 1.4e-05 25.2 6.0 0.0012 19.1 0.5 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GAX09663.1 - 0.0025 18.2 0.7 0.0025 18.2 0.7 2.8 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GAX09663.1 - 0.013 15.5 0.5 0.013 15.5 0.5 2.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Pox_Ag35 PF03286.14 GAX09663.1 - 4.5 7.0 10.9 2.5 7.8 0.5 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 GAX09663.1 - 9.6 6.7 13.1 22 5.5 6.2 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TraF_2 PF13729.6 GAX09664.1 - 4.7 6.5 7.2 1.1 8.5 0.7 2.4 2 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein LRR_4 PF12799.7 GAX09667.1 - 3.6e-12 46.3 17.7 0.032 14.7 1.2 7.1 6 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX09667.1 - 8.5e-12 44.7 18.2 0.0076 16.0 0.9 5.9 3 1 4 7 7 7 7 Leucine rich repeat LRR_1 PF00560.33 GAX09667.1 - 6.7e-05 22.9 10.3 38 5.4 0.2 8.6 10 1 0 10 10 10 1 Leucine Rich Repeat LRRNT_2 PF08263.12 GAX09667.1 - 0.0012 19.1 0.5 0.0012 19.1 0.5 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 GAX09668.1 - 2.3e-14 53.3 24.2 0.00024 21.4 0.4 6.9 4 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX09668.1 - 1.4e-13 50.4 19.1 0.00089 19.0 0.6 6.8 3 1 7 10 10 10 8 Leucine rich repeat LRR_1 PF00560.33 GAX09668.1 - 0.00097 19.4 8.6 40 5.3 0.0 7.1 10 0 0 10 10 10 0 Leucine Rich Repeat DUF3272 PF11676.8 GAX09668.1 - 0.039 14.2 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) LRRNT_2 PF08263.12 GAX09668.1 - 2.3 8.6 8.3 0.64 10.4 4.4 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Hus1 PF04005.12 GAX09669.1 - 1.6e-15 57.0 0.2 1.6e-14 53.7 0.2 1.9 1 1 0 1 1 1 1 Hus1-like protein LRR_8 PF13855.6 GAX09670.1 - 5.5e-23 80.5 24.2 0.00018 21.2 0.1 6.8 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 GAX09670.1 - 1.9e-13 50.3 19.6 0.00036 20.8 0.6 6.2 6 1 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX09670.1 - 5e-05 23.3 17.4 5.3 8.0 0.0 9.2 8 1 0 8 8 8 2 Leucine Rich Repeat LRRNT_2 PF08263.12 GAX09670.1 - 0.036 14.4 0.2 0.036 14.4 0.2 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Gar1 PF04410.14 GAX09671.1 - 5.5e-29 100.9 0.0 6.7e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glycos_transf_1 PF00534.20 GAX09672.1 - 1.7e-34 118.8 0.1 3.1e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX09672.1 - 2e-13 50.9 0.0 3.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX09672.1 - 1.7e-12 47.7 0.0 3.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAX09672.1 - 9.2e-08 32.7 0.3 2e-07 31.6 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX09672.1 - 0.00052 20.3 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Carboxyl_trans PF01039.22 GAX09673.1 - 2.8e-162 540.8 0.0 5e-162 540.0 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain ACC_central PF08326.12 GAX09673.1 - 8.4e-72 242.5 0.0 2.8e-69 234.1 0.0 3.0 1 1 1 2 2 2 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 GAX09673.1 - 3.2e-50 170.6 0.1 8e-50 169.3 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAX09673.1 - 8.9e-30 103.5 0.0 2.3e-29 102.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAX09673.1 - 7.2e-23 80.8 0.0 1.7e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAX09673.1 - 6.3e-12 45.2 0.0 2.3e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 GAX09673.1 - 6.3e-06 26.3 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 GAX09673.1 - 4.1e-05 23.2 0.0 9.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PNK3P PF08645.11 GAX09673.1 - 0.0035 17.1 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase Biotin_lipoyl_2 PF13533.6 GAX09673.1 - 0.033 14.0 0.0 0.95 9.3 0.0 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like Vac14_Fig4_bd PF11916.8 GAX09673.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding FAD_binding_4 PF01565.23 GAX09673.1 - 0.1 12.3 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain DUF3182 PF11379.8 GAX09673.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Phage_GP20 PF06810.11 GAX09673.1 - 1.3 8.8 4.6 3.5 7.4 0.0 3.5 4 0 0 4 4 4 0 Phage minor structural protein GP20 Hist_deacetyl PF00850.19 GAX09674.1 - 2.6e-61 207.8 0.0 4.5e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.7 GAX09674.1 - 1e-21 77.3 0.2 8.2e-07 29.5 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX09674.1 - 1.8e-20 73.0 0.8 3e-05 24.5 0.0 5.9 4 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX09674.1 - 1e-19 70.3 1.6 1.8e-07 31.3 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX09674.1 - 2.1e-15 56.4 6.1 2.6e-06 27.6 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 GAX09674.1 - 1.4e-12 46.6 1.6 0.00031 20.9 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Kinesin PF00225.23 GAX09675.1 - 1.2e-98 330.1 0.0 1.2e-98 330.1 0.0 3.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX09675.1 - 1.5e-20 73.7 0.0 1.2e-19 70.7 0.0 2.7 1 0 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 GAX09675.1 - 0.0013 19.0 9.0 0.0013 19.0 9.0 15.2 2 1 8 12 12 12 2 Autophagy protein 16 (ATG16) GAS PF13851.6 GAX09675.1 - 0.0018 17.7 24.7 0.0018 17.7 24.7 14.5 3 2 6 13 13 13 2 Growth-arrest specific micro-tubule binding DUF2695 PF10905.8 GAX09675.1 - 0.15 12.3 2.4 24 5.3 0.8 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) Hexapep PF00132.24 GAX09676.1 - 1.2e-07 31.1 3.8 0.00049 19.7 0.9 4.3 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAX09676.1 - 0.097 11.6 0.1 0.15 11.0 0.1 1.5 1 1 0 1 1 1 0 L-fucokinase AIM24 PF01987.17 GAX09677.1 - 2.2e-38 132.1 0.4 2.8e-38 131.8 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 GAX09678.1 - 2e-45 155.1 1.7 2.3e-45 154.9 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 GAX09679.1 - 2.1e-39 135.4 0.1 2.4e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 zf-rbx1 PF12678.7 GAX09680.1 - 4.5e-22 78.1 2.4 6.6e-22 77.5 2.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAX09680.1 - 3.3e-16 59.1 4.5 5.1e-16 58.5 4.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 GAX09680.1 - 2.3e-10 40.7 6.8 2e-09 37.7 6.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX09680.1 - 2.7e-10 39.9 2.7 1.9e-08 34.0 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX09680.1 - 4.5e-08 32.8 2.3 8.6e-08 31.9 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX09680.1 - 7.9e-08 32.2 0.8 1.7e-07 31.1 0.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX09680.1 - 1.1e-06 28.4 2.4 2.6e-06 27.3 2.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAX09680.1 - 2.4e-06 27.3 3.4 1.1e-05 25.2 0.3 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAX09680.1 - 3e-06 27.0 2.2 5.7e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX09680.1 - 1.5e-05 24.6 2.2 0.00036 20.2 0.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAX09680.1 - 7.5e-05 22.3 1.2 7.5e-05 22.3 1.2 2.1 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 GAX09680.1 - 0.00038 20.5 4.0 0.0027 17.8 1.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zinc_ribbon_16 PF17034.5 GAX09680.1 - 0.0019 18.4 3.9 0.012 15.9 3.9 2.1 1 1 0 1 1 1 1 Zinc-ribbon like family zf-RING_4 PF14570.6 GAX09680.1 - 0.0022 17.8 2.2 0.0035 17.1 0.1 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 GAX09680.1 - 0.0028 17.5 0.2 0.005 16.6 0.2 1.4 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 GAX09680.1 - 0.0089 16.0 4.1 0.029 14.4 1.7 2.4 2 1 0 2 2 2 1 Zinc-finger TerY_C PF15616.6 GAX09680.1 - 0.011 15.8 1.1 0.013 15.6 0.1 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING-like PF08746.11 GAX09680.1 - 0.013 15.7 1.3 0.013 15.7 1.3 1.8 2 0 0 2 2 2 0 RING-like domain Rtf2 PF04641.12 GAX09680.1 - 0.015 14.7 1.2 0.023 14.0 0.1 1.7 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_10 PF16685.5 GAX09680.1 - 0.05 13.7 0.7 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Baculo_RING PF05883.11 GAX09680.1 - 0.085 12.8 2.1 0.31 11.0 2.1 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.7 GAX09680.1 - 0.098 12.8 2.2 0.098 12.8 2.2 2.3 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 GAX09680.1 - 0.81 9.9 7.4 0.29 11.3 2.7 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain Methyltransf_4 PF02390.17 GAX09681.1 - 5.5e-07 29.2 0.0 4.8e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 GAX09681.1 - 0.00027 20.8 0.0 0.00077 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX09681.1 - 0.0014 19.3 0.0 0.0053 17.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX09681.1 - 0.035 14.1 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain IKI3 PF04762.12 GAX09682.1 - 6.4e-149 497.7 0.0 1.1e-140 470.5 0.0 2.2 2 0 0 2 2 2 2 IKI3 family TPR_2 PF07719.17 GAX09682.1 - 0.029 14.5 0.0 4.1 7.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.9 GAX09682.1 - 0.084 12.5 11.0 0.088 12.4 1.8 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_12 PF13424.6 GAX09682.1 - 0.094 13.0 0.4 44 4.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_Tnp_IS91 PF14319.6 GAX09683.1 - 0.0028 17.6 1.3 0.0047 16.9 1.3 1.3 1 0 0 1 1 1 1 Transposase zinc-binding domain Pollen_allerg_1 PF01357.21 GAX09685.1 - 0.04 13.9 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Pollen allergen Chloroa_b-bind PF00504.21 GAX09686.1 - 2.1e-31 109.6 0.2 3e-31 109.1 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DnaJ PF00226.31 GAX09687.1 - 2.6e-13 49.9 3.3 5.1e-13 48.9 3.3 1.5 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 GAX09687.1 - 9.2e-07 28.8 20.8 0.0011 18.7 16.0 3.9 3 1 0 3 3 3 2 Transmembrane Fragile-X-F protein Phospholamban PF04272.14 GAX09687.1 - 0.23 10.9 0.0 0.23 10.9 0.0 2.4 3 0 0 3 3 3 0 Phospholamban TFIIA PF03153.13 GAX09688.1 - 0.00036 20.7 31.9 0.00036 20.7 31.9 2.1 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 GAX09688.1 - 0.0012 18.6 6.0 0.0031 17.3 6.0 1.7 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GlutR_dimer PF00745.20 GAX09688.1 - 0.12 12.8 0.3 0.34 11.4 0.3 1.8 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain CDC24_OB1 PF17246.2 GAX09688.1 - 0.2 11.8 7.9 1.1 9.4 3.8 3.4 3 1 0 3 3 3 0 Cell division control protein 24, OB domain 1 NOA36 PF06524.12 GAX09688.1 - 1 8.6 10.7 1.7 7.9 10.7 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 GAX09688.1 - 1.3 7.4 6.6 3 6.3 6.6 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DinB PF05163.12 GAX09691.1 - 0.046 13.6 1.5 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 DinB family Thioredoxin PF00085.20 GAX09692.1 - 2.8e-10 40.1 0.0 4.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX09692.1 - 0.033 14.5 0.1 0.078 13.3 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like MFS_1 PF07690.16 GAX09694.1 - 6.2e-21 74.7 18.7 9.3e-21 74.1 18.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_10 PF13460.6 GAX09695.1 - 1.4e-23 83.8 0.0 2.7e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX09695.1 - 2.4e-13 50.2 0.0 1.1e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAX09695.1 - 1.7e-11 44.1 0.0 3.4e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAX09695.1 - 1e-08 34.9 0.1 1.6e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX09695.1 - 4.3e-07 29.7 0.1 7.2e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX09695.1 - 3.4e-06 27.1 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAX09695.1 - 8.5e-06 25.4 0.0 2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAX09695.1 - 0.00015 20.8 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX09695.1 - 0.063 12.4 0.0 0.3 10.2 0.0 1.9 1 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 GAX09695.1 - 0.088 11.9 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain CX PF01705.19 GAX09696.1 - 0.013 16.0 3.8 0.79 10.3 0.0 3.0 3 0 0 3 3 3 0 CX module UQ_con PF00179.26 GAX09697.1 - 7.8e-10 38.6 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Topoisom_bac PF01131.20 GAX09699.1 - 2.3e-102 343.1 0.0 1.1e-93 314.5 0.0 2.3 2 0 0 2 2 2 2 DNA topoisomerase HMG_box PF00505.19 GAX09699.1 - 7e-38 128.9 5.6 1.1e-13 51.4 0.1 3.7 3 0 0 3 3 3 3 HMG (high mobility group) box Toprim_C_rpt PF13368.6 GAX09699.1 - 6.2e-30 103.0 0.2 3.4e-09 36.6 0.0 5.2 4 1 0 4 4 4 4 Topoisomerase C-terminal repeat HMG_box_2 PF09011.10 GAX09699.1 - 4.9e-25 87.9 6.5 1.2e-07 32.2 0.1 3.6 3 0 0 3 3 3 3 HMG-box domain Toprim PF01751.22 GAX09699.1 - 3e-23 82.0 0.0 8.6e-23 80.5 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 GAX09699.1 - 0.0014 19.0 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain MarR_2 PF12802.7 GAX09699.1 - 0.0069 16.2 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 MarR family DUF4107 PF13389.6 GAX09699.1 - 0.057 13.6 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) NuA4 PF09340.10 GAX09700.1 - 7.4e-10 38.6 0.2 2.8e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 AATF-Che1 PF13339.6 GAX09700.1 - 0.46 11.2 6.0 9.7 6.9 6.0 2.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor UAA PF08449.11 GAX09701.1 - 1.3e-48 165.7 15.3 3e-48 164.6 15.3 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX09701.1 - 7.9e-08 32.6 21.1 3e-06 27.5 12.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family PilM PF07419.12 GAX09701.1 - 0.11 12.7 0.3 0.26 11.5 0.3 1.6 1 0 0 1 1 1 0 PilM DUF2070 PF09843.9 GAX09701.1 - 0.14 10.4 4.7 0.23 9.7 4.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_trans_1_2 PF13524.6 GAX09703.1 - 7.8e-14 51.8 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_23 PF13489.6 GAX09703.1 - 0.00046 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX09703.1 - 0.00058 20.5 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX09703.1 - 0.0049 17.6 0.0 0.017 15.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 GAX09703.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.14 GAX09703.1 - 0.038 13.5 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TOC159_MAD PF11886.8 GAX09705.1 - 0.1 11.5 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain ELMO_CED12 PF04727.13 GAX09706.1 - 6e-13 49.3 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Chloroa_b-bind PF00504.21 GAX09707.1 - 0.00017 22.1 0.1 0.00034 21.2 0.1 1.6 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Sorting_nexin PF03700.13 GAX09708.1 - 0.044 14.4 0.0 0.048 14.2 0.0 1.1 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain VirB8 PF04335.13 GAX09708.1 - 0.14 12.0 0.2 7.4 6.3 0.0 2.0 2 0 0 2 2 2 0 VirB8 protein Gram_pos_anchor PF00746.21 GAX09708.1 - 0.25 11.3 2.7 5 7.1 2.1 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Selenoprotein_S PF06936.11 GAX09709.1 - 0.026 14.3 3.7 0.049 13.4 3.7 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF2570 PF10828.8 GAX09709.1 - 0.29 11.0 1.3 0.54 10.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Ank_2 PF12796.7 GAX09710.1 - 1.1e-12 48.4 3.1 0.024 15.2 0.0 6.5 4 1 3 7 7 7 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 GAX09710.1 - 3.1e-08 33.3 0.0 0.0033 16.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ank_4 PF13637.6 GAX09710.1 - 1.2e-06 28.9 3.0 0.12 13.0 0.1 6.5 8 0 0 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX09710.1 - 3.3e-06 27.0 12.3 1.3 9.8 0.1 7.9 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 GAX09710.1 - 5.3e-06 26.6 17.1 0.24 11.9 0.1 8.1 9 1 0 9 9 9 2 Ankyrin repeat Pkinase_Tyr PF07714.17 GAX09710.1 - 0.00024 20.5 0.0 0.00092 18.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_5 PF13857.6 GAX09710.1 - 0.00032 20.9 3.7 16 5.9 0.1 6.0 6 0 0 6 6 6 1 Ankyrin repeats (many copies) NOA36 PF06524.12 GAX09710.1 - 3.5 6.9 6.4 5.9 6.1 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein ELO PF01151.18 GAX09711.1 - 2.3e-59 201.0 21.4 2.9e-59 200.6 21.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 GAX09712.1 - 4e-64 216.6 21.2 5.4e-64 216.1 21.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 GAX09713.1 - 7e-67 225.6 24.0 8.9e-67 225.2 24.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GFO_IDH_MocA PF01408.22 GAX09714.1 - 2.7e-19 70.2 0.0 5.2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NMT1_2 PF13379.6 GAX09714.1 - 0.065 12.9 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 NMT1-like family XRN_N PF03159.18 GAX09715.1 - 4.8e-88 294.7 0.0 6.7e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 GAX09715.1 - 7.3e-87 292.2 3.7 7.3e-87 292.2 3.7 2.9 2 1 0 2 2 2 1 Xrn1 helical domain Proteasome PF00227.26 GAX09715.1 - 2.3e-41 141.4 0.0 6.6e-41 139.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit XRN1_D1 PF18332.1 GAX09715.1 - 3.2e-16 59.7 0.0 8.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain Pribosyltran PF00156.27 GAX09716.1 - 5.2e-15 55.3 0.0 7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAX09716.1 - 0.028 13.9 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DHHC PF01529.20 GAX09717.1 - 1.8e-30 105.8 13.9 1.8e-30 105.8 13.9 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF3974 PF13120.6 GAX09717.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) PKcGMP_CC PF16808.5 GAX09718.1 - 0.023 14.6 0.2 0.023 14.6 0.2 11.2 14 0 0 14 14 14 0 Coiled-coil N-terminus of cGMP-dependent protein kinase T4_neck-protein PF11649.8 GAX09718.1 - 0.067 12.5 0.8 8.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Virus neck protein Xpo1 PF08389.12 GAX09719.1 - 5.7e-10 39.4 2.8 0.019 15.0 0.0 4.7 5 1 0 5 5 5 3 Exportin 1-like protein HMG_box PF00505.19 GAX09720.1 - 8.6e-12 45.3 2.9 6.8e-07 29.6 0.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX09720.1 - 4.8e-07 30.3 11.9 6.6e-05 23.4 1.1 3.0 3 0 0 3 3 3 2 HMG-box domain YABBY PF04690.13 GAX09720.1 - 1.4e-05 25.7 1.4 3e-05 24.6 0.4 2.0 2 0 0 2 2 2 1 YABBY protein GNVR PF13807.6 GAX09720.1 - 5.4 7.0 8.5 19 5.2 0.1 2.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase MORN PF02493.20 GAX09721.1 - 2e-33 112.3 40.3 2.1e-06 27.3 0.9 7.3 7 0 0 7 7 7 7 MORN repeat YniB PF14002.6 GAX09722.1 - 0.16 11.7 2.4 33 4.2 0.1 3.4 3 0 0 3 3 3 0 YniB-like protein Latarcin PF10279.9 GAX09722.1 - 0.41 11.1 2.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Latarcin precursor PT PF04886.12 GAX09724.1 - 0.2 11.2 1.4 2.8 7.6 0.3 2.0 2 0 0 2 2 2 0 PT repeat AAA_25 PF13481.6 GAX09725.1 - 1.2e-20 73.9 0.0 2.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAX09725.1 - 2.3e-12 46.8 0.0 3.3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 GAX09725.1 - 2.9e-07 30.8 0.0 7.6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Toprim-like AAA_16 PF13191.6 GAX09725.1 - 6e-06 26.7 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX09725.1 - 1.8e-05 25.1 0.0 4.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 GAX09725.1 - 4e-05 23.1 0.0 0.00012 21.6 0.0 1.7 1 1 0 1 1 1 1 KaiC Toprim_4 PF13662.6 GAX09725.1 - 5.6e-05 23.5 0.0 0.00092 19.6 0.0 2.5 2 0 0 2 2 2 1 Toprim domain T2SSE PF00437.20 GAX09725.1 - 0.00029 20.0 0.0 0.00052 19.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 GAX09725.1 - 0.0052 16.5 0.1 0.015 15.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 GAX09725.1 - 0.0075 15.9 0.0 0.022 14.3 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAX09725.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 GAX09725.1 - 0.0089 16.6 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter CbiA PF01656.23 GAX09725.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 GAX09725.1 - 0.012 15.6 0.1 0.028 14.4 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 GAX09725.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX09725.1 - 0.013 16.0 1.6 0.019 15.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAX09725.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF853 PF05872.12 GAX09725.1 - 0.022 13.4 0.2 0.43 9.1 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) ATP_bind_1 PF03029.17 GAX09725.1 - 0.046 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Toprim_N PF08275.11 GAX09725.1 - 0.057 13.5 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 DNA primase catalytic core, N-terminal domain PhoH PF02562.16 GAX09725.1 - 0.067 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KIX_2 PF16987.5 GAX09725.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 KIX domain SRP54 PF00448.22 GAX09725.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Toprim_3 PF13362.6 GAX09725.1 - 0.1 13.0 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Toprim domain DUF2075 PF09848.9 GAX09725.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 GAX09725.1 - 0.19 11.9 0.2 1 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 GAX09726.1 - 4.7e-29 100.4 0.0 5.7e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX09726.1 - 1.7e-08 34.9 0.1 2e-07 31.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAX09726.1 - 1.1e-07 31.6 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 GAX09726.1 - 1.9e-06 28.0 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX09726.1 - 2.5e-06 27.7 0.1 1.5e-05 25.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 GAX09726.1 - 8.5e-06 25.3 0.0 9.5e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 GAX09726.1 - 0.00039 20.3 0.0 0.00085 19.2 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GAX09726.1 - 0.0058 16.4 0.0 0.035 13.8 0.0 1.8 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.24 GAX09726.1 - 0.0064 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin HyaE PF07449.11 GAX09726.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 GAX09726.1 - 0.092 12.4 0.1 0.23 11.1 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 GAX09726.1 - 0.17 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain DOMON PF03351.17 GAX09727.1 - 4e-16 59.4 0.0 4.7e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 DOMON domain Cytochrom_B561 PF03188.16 GAX09727.1 - 9.7e-05 22.5 0.6 0.00037 20.7 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 GAX09727.1 - 0.0056 16.4 0.2 0.14 11.8 0.1 2.4 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 GAX09727.1 - 0.035 13.9 0.3 0.35 10.7 0.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) DUF202 PF02656.15 GAX09727.1 - 0.71 10.4 4.9 0.74 10.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Proton_antipo_N PF00662.20 GAX09727.1 - 1.4 9.1 5.2 25 5.1 1.1 2.7 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Ank_3 PF13606.6 GAX09728.1 - 0.00054 20.2 0.0 0.076 13.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 GAX09728.1 - 0.0011 19.4 0.3 0.041 14.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX09728.1 - 0.0035 17.9 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX09728.1 - 0.021 15.1 0.2 2.8 8.3 0.1 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 GAX09728.1 - 0.096 13.2 1.0 0.53 10.8 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat BSP_II PF05432.11 GAX09728.1 - 6.2 6.4 42.1 0.044 13.5 32.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF1336 PF07059.12 GAX09730.1 - 3.4e-49 168.0 0.0 5.9e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) AAA PF00004.29 GAX09731.1 - 4.8e-15 56.2 0.0 1.1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX09731.1 - 6e-09 36.3 0.0 1.7e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 GAX09731.1 - 1e-07 31.9 0.0 0.099 12.5 0.0 4.1 4 0 0 4 4 4 2 BAH domain AAA_16 PF13191.6 GAX09731.1 - 1.2e-06 29.0 0.0 3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 GAX09731.1 - 1.7e-05 24.8 0.1 4.6e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 GAX09731.1 - 1.8e-05 24.7 0.0 0.00024 21.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 GAX09731.1 - 0.0011 19.0 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 GAX09731.1 - 0.0036 16.6 0.2 0.014 14.7 0.0 2.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 GAX09731.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAX09731.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAX09731.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 NTPase SR-25 PF10500.9 GAX09732.1 - 0.00033 20.4 22.6 0.00033 20.4 22.6 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 GAX09732.1 - 0.0014 18.9 17.5 0.0033 17.7 17.5 1.6 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 HemY_N PF07219.13 GAX09732.1 - 0.11 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 HemY protein N-terminus RNA_polI_A34 PF08208.11 GAX09732.1 - 0.55 10.3 31.6 1.2 9.2 31.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.12 GAX09732.1 - 0.7 10.1 17.1 1.1 9.4 17.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family LapA_dom PF06305.11 GAX09732.1 - 2.5 8.0 0.0 2.5 8.0 0.0 2.5 2 1 0 2 2 1 0 Lipopolysaccharide assembly protein A domain RNA_pol_Rpc4 PF05132.14 GAX09732.1 - 3 8.2 15.9 31 5.0 16.4 2.3 3 0 0 3 3 2 0 RNA polymerase III RPC4 NARP1 PF12569.8 GAX09732.1 - 3.2 6.5 22.5 6.3 5.6 22.5 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 G0-G1_switch_2 PF15103.6 GAX09732.1 - 3.5 8.1 9.5 1e+02 3.4 9.7 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 MAP17 PF15807.5 GAX09732.1 - 3.9 7.7 21.2 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DDHD PF02862.17 GAX09732.1 - 4.7 7.3 10.4 8.9 6.4 10.4 1.4 1 0 0 1 1 1 0 DDHD domain TMEM214 PF10151.9 GAX09732.1 - 8.5 4.7 14.9 13 4.1 14.9 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator EIIBC-GUT_N PF03612.14 GAX09732.1 - 8.8 6.0 9.2 17 5.1 9.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DHHC PF01529.20 GAX09733.1 - 1.7e-27 96.2 0.7 4e-27 95.0 0.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase LapA_dom PF06305.11 GAX09733.1 - 0.022 14.6 0.6 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Sigma_reg_N PF13800.6 GAX09733.1 - 0.035 14.4 0.3 0.93 9.8 0.0 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal RRM_1 PF00076.22 GAX09734.1 - 2.2e-17 62.6 0.0 3.9e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAX09734.1 - 0.017 15.2 0.1 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif DUF981 PF06168.11 GAX09735.1 - 0.011 15.7 9.5 0.029 14.3 9.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF981) DUF2070 PF09843.9 GAX09735.1 - 1.4 7.2 11.0 2 6.6 11.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SBF PF01758.16 GAX09736.1 - 2.1e-32 112.4 18.8 4.2e-32 111.4 18.8 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 GAX09736.1 - 1.8e-14 53.8 25.5 2.5e-14 53.3 25.5 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Glycos_transf_N PF04413.16 GAX09736.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) VPS28 PF03997.12 GAX09737.1 - 5.8e-57 192.4 0.1 6.7e-57 192.2 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein PhoD PF09423.10 GAX09738.1 - 5.1e-13 48.8 0.2 1.2e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase DUF3383 PF11863.8 GAX09738.1 - 0.015 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) RRM_1 PF00076.22 GAX09739.1 - 1.5e-17 63.2 0.0 2.5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX09739.1 - 2.4e-06 27.2 0.0 4.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_1 PF00685.27 GAX09740.1 - 1e-10 41.5 0.2 6.7e-10 38.9 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX09740.1 - 3.5e-07 30.8 0.4 0.00013 22.4 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family DUF3150 PF11348.8 GAX09740.1 - 0.15 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Peptidase_C11 PF03415.14 GAX09741.1 - 7.6e-29 101.2 0.1 1.1e-28 100.7 0.1 1.2 1 0 0 1 1 1 1 Clostripain family Period_C PF12114.8 GAX09741.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Invasin_D3 PF09134.10 GAX09741.1 - 0.13 12.5 2.4 0.96 9.8 0.2 3.0 3 0 0 3 3 3 0 Invasin, domain 3 NmrA PF05368.13 GAX09742.1 - 2.5e-15 56.7 0.3 2.2e-14 53.6 0.3 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAX09742.1 - 5.3e-10 39.5 0.3 7.8e-10 38.9 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding PALP PF00291.25 GAX09742.1 - 0.088 12.2 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Scramblase PF03803.15 GAX09743.1 - 5.1e-27 94.6 4.0 2.9e-24 85.6 4.0 2.1 1 1 0 1 1 1 1 Scramblase PPR_1 PF12854.7 GAX09744.1 - 3.4e-14 52.2 5.7 8.3e-06 25.4 0.0 7.4 7 1 0 7 7 7 3 PPR repeat PPR PF01535.20 GAX09744.1 - 7.9e-14 50.9 6.9 6.8e-06 26.0 0.0 5.7 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.6 GAX09744.1 - 1.3e-12 47.7 10.1 0.0007 19.7 0.0 8.0 7 2 2 9 9 9 4 PPR repeat family PPR_3 PF13812.6 GAX09744.1 - 2e-12 47.0 0.0 0.0029 17.7 0.0 5.7 4 2 2 6 6 6 2 Pentatricopeptide repeat domain Wzy_C_2 PF11846.8 GAX09744.1 - 0.008 16.1 0.0 7.7 6.4 0.0 3.2 3 0 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal ATP13 PF12921.7 GAX09744.1 - 0.042 13.7 0.0 3.1 7.7 0.0 3.5 3 1 1 4 4 4 0 Mitochondrial ATPase expression TPR_14 PF13428.6 GAX09744.1 - 0.11 13.4 0.1 3.5 8.7 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_4 PF12799.7 GAX09745.1 - 0.8 10.2 4.6 14 6.3 0.1 4.6 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX09745.1 - 2 8.2 5.2 6.6 6.6 0.0 4.3 7 0 0 7 7 7 0 Leucine rich repeat Nuc_sug_transp PF04142.15 GAX09746.1 - 5e-26 91.6 7.3 8.3e-26 90.9 7.3 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAX09746.1 - 0.00051 20.2 24.3 0.0023 18.1 9.9 2.6 2 0 0 2 2 2 2 EamA-like transporter family 2OG-FeII_Oxy_3 PF13640.6 GAX09747.1 - 9.2e-13 48.9 0.0 1.9e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TORC_M PF12885.7 GAX09747.1 - 0.098 12.6 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain Glyco_hydro_1 PF00232.18 GAX09748.1 - 1.8e-74 250.9 0.0 2.1e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Lipase_GDSL_2 PF13472.6 GAX09749.1 - 5.1e-31 108.4 0.0 3.1e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX09749.1 - 1.7e-10 41.2 0.0 0.00015 21.8 0.0 3.0 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 GAX09749.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 GAX09750.1 - 4.8e-11 43.4 0.0 6.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX09750.1 - 8.3e-05 22.6 0.0 0.00017 21.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAX09751.1 - 2.4e-08 34.6 0.1 3.7e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX09751.1 - 6.5e-07 29.5 0.1 1e-06 28.8 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NrsF PF06532.11 GAX09751.1 - 0.083 12.6 0.2 0.25 11.0 0.3 1.6 2 0 0 2 2 2 0 Negative regulator of sigma F RNA_pol_Rpb1_5 PF04998.17 GAX09753.1 - 2.3e-93 312.5 0.0 3.8e-93 311.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAX09753.1 - 6.8e-73 244.4 0.0 1.6e-72 243.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 GAX09753.1 - 7.8e-73 245.5 0.0 1.6e-72 244.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_6 PF04992.14 GAX09753.1 - 2.6e-58 197.0 0.1 4.7e-58 196.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 GAX09753.1 - 7.9e-42 142.8 0.1 2.3e-41 141.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 GAX09753.1 - 8.8e-42 142.3 1.8 2.3e-41 141.0 1.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 GAX09753.1 - 7.3e-36 122.4 0.2 1.9e-35 121.0 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 GAX09753.1 - 6.5e-10 38.8 184.4 0.019 15.3 14.0 10.8 10 0 0 10 10 10 7 RNA polymerase Rpb1 C-terminal repeat DUF2524 PF10732.9 GAX09753.1 - 0.097 13.0 0.1 0.39 11.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) FliJ PF02050.16 GAX09753.1 - 0.13 12.5 0.5 0.27 11.5 0.5 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein PUB PF09409.10 GAX09755.1 - 2e-16 59.7 0.0 3.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 GAX09755.1 - 1.9e-10 40.3 0.0 3.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family GerD PF17898.1 GAX09755.1 - 0.0085 16.0 3.1 0.02 14.9 2.0 2.2 2 0 0 2 2 2 1 Spore germination GerD central core domain Rad60-SLD_2 PF13881.6 GAX09755.1 - 0.0097 16.0 0.0 0.034 14.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAX09755.1 - 0.017 15.7 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain STI1 PF17830.1 GAX09755.1 - 0.021 14.7 18.7 0.61 10.1 2.2 2.9 1 1 0 2 2 2 0 STI1 domain Ubiquitin_5 PF18037.1 GAX09755.1 - 0.046 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain NDUF_B4 PF07225.12 GAX09755.1 - 0.097 12.6 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) EthD PF07110.11 GAX09755.1 - 0.17 13.1 0.8 2.1 9.6 0.1 2.6 2 0 0 2 2 2 0 EthD domain Choline_transpo PF04515.12 GAX09756.1 - 1e-68 232.0 25.8 1e-68 232.0 25.8 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF2615 PF11027.8 GAX09756.1 - 1.8 8.7 0.0 1.8 8.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Rhodanese PF00581.20 GAX09757.1 - 1.8e-20 73.4 0.0 2.3e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Med1 PF10744.9 GAX09757.1 - 0.045 12.8 0.1 0.062 12.3 0.1 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Rhodanese PF00581.20 GAX09758.1 - 5.3e-12 46.2 0.0 1.5e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain LRR_6 PF13516.6 GAX09759.1 - 0.0002 21.1 22.2 0.027 14.5 0.0 7.8 10 0 0 10 10 10 3 Leucine Rich repeat LRR_8 PF13855.6 GAX09759.1 - 0.054 13.3 1.0 0.33 10.7 0.5 2.6 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 GAX09759.1 - 0.095 13.2 0.2 0.095 13.2 0.2 3.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) Pyr_redox_2 PF07992.14 GAX09760.1 - 7e-13 48.5 0.0 3.6e-06 26.4 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX09760.1 - 0.00042 20.8 0.0 0.0013 19.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX09760.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 GAX09760.1 - 0.045 13.8 0.0 0.22 11.5 0.0 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Amidohydro_1 PF01979.20 GAX09761.1 - 3.8e-08 33.0 0.1 5e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 GAX09761.1 - 0.00017 21.5 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Rotamase PF00639.21 GAX09762.1 - 3.1e-20 72.9 0.3 1e-19 71.3 0.0 2.0 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX09762.1 - 1.3e-19 70.9 0.0 3.6e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 PPIC-type PPIASE domain GST_N_3 PF13417.6 GAX09762.1 - 8.1e-17 61.4 0.0 1e-08 35.4 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX09762.1 - 1.3e-06 28.7 0.0 1.4e-05 25.4 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX09762.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Rotamase_2 PF13145.6 GAX09762.1 - 0.04 14.7 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain SANT_DAMP1_like PF16282.5 GAX09763.1 - 0.025 14.8 0.0 0.097 12.9 0.0 2.0 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Glyco_transf_25 PF01755.17 GAX09763.1 - 0.029 14.2 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) HEAT_2 PF13646.6 GAX09763.1 - 0.044 14.2 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats ERG4_ERG24 PF01222.17 GAX09765.1 - 1.8e-70 237.9 15.1 2.1e-70 237.6 15.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DNAPolymera_Pol PF11590.8 GAX09767.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Ku PF02735.16 GAX09768.1 - 1.5e-26 93.4 0.1 4.9e-26 91.7 0.0 1.9 3 0 0 3 3 3 1 Ku70/Ku80 beta-barrel domain SAP PF02037.27 GAX09768.1 - 1.1e-07 31.4 2.9 2e-07 30.6 1.1 2.2 2 0 0 2 2 2 1 SAP domain Telomere_Sde2_2 PF13297.6 GAX09768.1 - 0.0016 18.0 0.3 0.0079 15.8 0.1 2.1 2 0 0 2 2 2 1 Telomere stability C-terminal Ku_C PF03730.14 GAX09768.1 - 0.01 16.5 0.5 0.056 14.1 0.0 2.4 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm BCIP PF13862.6 GAX09769.1 - 2.8e-36 125.2 0.0 2.8e-36 125.2 0.0 2.1 2 1 0 2 2 2 1 p21-C-terminal region-binding protein SDA1 PF05285.12 GAX09769.1 - 0.49 9.8 14.4 0.63 9.4 14.4 1.1 1 0 0 1 1 1 0 SDA1 ORC6 PF05460.13 GAX09769.1 - 1.1 8.4 5.9 1.9 7.7 5.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CDC45 PF02724.14 GAX09769.1 - 1.2 7.4 10.0 1.4 7.1 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAX09769.1 - 2.5 6.2 15.8 3.3 5.8 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family YqaJ PF09588.10 GAX09770.1 - 0.035 14.2 0.1 1.5 9.0 0.0 2.6 2 1 0 2 2 2 0 YqaJ-like viral recombinase domain Trypsin PF00089.26 GAX09771.1 - 2.4e-46 158.3 0.2 2.9e-46 158.1 0.2 1.1 1 0 0 1 1 1 1 Trypsin RRM_9 PF18444.1 GAX09771.1 - 0.097 12.5 0.1 3.4 7.6 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif UDPGT PF00201.18 GAX09772.1 - 8.6e-05 21.5 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Gly_transf_sug PF04488.15 GAX09774.1 - 3.7e-09 37.1 0.1 1.1e-08 35.6 0.1 1.9 1 1 1 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 GAX09774.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain NUDIX PF00293.28 GAX09775.1 - 1.5e-13 51.0 0.1 2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain FAP PF07174.11 GAX09777.1 - 2 7.8 14.3 2.7 7.4 14.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PAP_fibrillin PF04755.12 GAX09779.1 - 1.1e-07 32.1 0.1 5.4e-05 23.2 0.0 3.0 2 1 0 2 2 2 2 PAP_fibrillin Gp49 PF05973.14 GAX09779.1 - 0.15 12.2 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) HAP1_N PF04849.13 GAX09780.1 - 0.00082 18.7 1.0 0.00088 18.6 1.0 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Leu_zip PF15294.6 GAX09780.1 - 0.001 18.6 0.6 0.0011 18.6 0.6 1.0 1 0 0 1 1 1 1 Leucine zipper TMF_DNA_bd PF12329.8 GAX09780.1 - 0.0012 18.8 6.8 0.2 11.7 1.2 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding KIAA1430 PF13879.6 GAX09780.1 - 0.0025 18.5 0.6 0.0031 18.2 0.6 1.1 1 0 0 1 1 1 1 KIAA1430 homologue SKA2 PF16740.5 GAX09780.1 - 0.0068 16.2 2.6 0.0089 15.8 2.6 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 GIT_CC PF16559.5 GAX09780.1 - 0.0091 15.8 2.9 0.0091 15.8 2.9 2.2 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 GAX09780.1 - 0.0098 16.3 5.4 0.015 15.7 5.4 1.4 1 1 0 1 1 1 1 Cell division protein ZapB betaPIX_CC PF16523.5 GAX09780.1 - 0.013 15.3 0.5 0.02 14.7 0.5 1.4 1 0 0 1 1 1 0 betaPIX coiled coil bZIP_2 PF07716.15 GAX09780.1 - 0.014 15.5 1.9 0.014 15.5 1.9 1.8 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 GAX09780.1 - 0.026 14.6 3.7 0.036 14.1 2.0 1.9 1 1 1 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 GAX09780.1 - 0.034 14.5 1.7 0.053 13.8 1.6 1.5 1 1 0 1 1 1 0 TSC-22/dip/bun family HIP1_clath_bdg PF16515.5 GAX09780.1 - 0.25 12.0 7.5 0.37 11.4 7.5 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LPP PF04728.13 GAX09780.1 - 0.74 10.2 5.3 0.3 11.5 0.5 2.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper HSF_DNA-bind PF00447.17 GAX09782.1 - 8.8e-41 138.4 4.3 5.7e-20 71.7 0.0 2.6 3 0 0 3 3 3 2 HSF-type DNA-binding Lin0512_fam PF09585.10 GAX09782.1 - 1.2e-07 31.7 0.0 2.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) Ets PF00178.22 GAX09782.1 - 0.13 12.7 0.0 30 5.2 0.0 2.6 2 0 0 2 2 2 0 Ets-domain EcKinase PF02958.20 GAX09783.1 - 1.9e-13 50.4 0.0 1.1e-10 41.4 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 GAX09783.1 - 2.7e-12 47.1 0.1 4e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAX09783.1 - 2.3e-08 33.4 0.1 3.3e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 GAX09783.1 - 4.1e-06 26.4 0.0 0.00036 20.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 GAX09783.1 - 0.00031 20.4 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 GAX09783.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family JAB PF01398.21 GAX09784.1 - 5.3e-33 113.5 1.0 5.9e-33 113.3 0.1 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAX09784.1 - 4.8e-14 52.7 0.7 8.9e-14 51.9 0.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 GAX09784.1 - 2.4e-06 27.3 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 GAX09784.1 - 0.0061 16.7 0.2 0.011 15.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) CRAL_TRIO PF00650.20 GAX09785.1 - 5.6e-11 42.4 0.0 9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Frankia_peptide PF14407.6 GAX09785.1 - 0.071 13.1 2.3 0.15 12.0 2.3 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. 2OG-FeII_Oxy PF03171.20 GAX09786.1 - 0.00017 22.0 0.0 0.0006 20.2 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CbtA_toxin PF06755.12 GAX09787.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system Mpv17_PMP22 PF04117.12 GAX09788.1 - 5.1e-14 52.2 1.2 1.1e-13 51.2 1.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family HECT PF00632.25 GAX09789.1 - 3e-15 56.5 0.0 5.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 GAX09789.1 - 0.00018 21.6 0.0 0.00051 20.1 0.0 1.7 1 0 0 1 1 1 1 SPRY domain C1_2 PF03107.16 GAX09789.1 - 0.54 10.6 17.8 0.14 12.5 4.9 2.8 2 0 0 2 2 2 0 C1 domain Pkinase PF00069.25 GAX09790.1 - 1.9e-49 168.4 0.1 3.6e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09790.1 - 1.9e-25 89.6 0.0 3.7e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 GAX09790.1 - 1.4e-06 28.3 0.3 2.8e-06 27.3 0.3 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Kdo PF06293.14 GAX09790.1 - 5.8e-05 22.5 0.4 0.00012 21.5 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I_2 PF17014.5 GAX09790.1 - 0.0023 18.0 0.1 0.0051 16.9 0.1 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein APH PF01636.23 GAX09790.1 - 0.0031 17.5 0.2 0.0031 17.5 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX09790.1 - 0.0061 16.2 0.3 0.03 13.9 0.1 2.2 2 0 0 2 2 2 1 RIO1 family TPR_14 PF13428.6 GAX09790.1 - 0.12 13.3 3.8 2.5 9.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX09790.1 - 5.3 7.6 5.9 13 6.4 3.5 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.6 GAX09791.1 - 1.2e-06 29.6 0.0 3.9e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX09791.1 - 0.00051 19.9 0.0 0.00091 19.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAX09791.1 - 0.0043 17.0 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAX09791.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Membralin PF09746.9 GAX09792.1 - 1.5e-07 30.8 1.3 1.5e-07 30.8 1.3 1.7 2 0 0 2 2 2 1 Tumour-associated protein UPF0449 PF15136.6 GAX09793.1 - 0.013 15.9 0.9 0.033 14.6 0.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 BPL_LplA_LipB PF03099.19 GAX09794.1 - 2.2e-10 40.5 0.0 3.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family YqgF PF14639.6 GAX09795.1 - 0.032 14.0 0.7 0.069 12.9 0.7 1.5 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 CsgF PF10614.9 GAX09795.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.8 3 0 0 3 3 3 0 Type VIII secretion system (T8SS), CsgF protein CRR7 PF12095.8 GAX09795.1 - 0.9 10.0 10.4 0.18 12.3 5.8 2.3 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Sugarporin_N PF11471.8 GAX09795.1 - 1.1 9.3 4.4 2.8 8.0 4.4 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension TMEM51 PF15345.6 GAX09796.1 - 0.025 14.4 0.2 0.069 13.0 0.0 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 Gram_pos_anchor PF00746.21 GAX09796.1 - 0.096 12.6 0.5 0.24 11.4 0.5 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Thr_synth_N PF14821.6 GAX09797.1 - 2.7e-24 85.2 0.0 6.9e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 GAX09797.1 - 8.1e-13 48.4 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Siva PF05458.12 GAX09798.1 - 9.3e-06 25.4 15.7 4.4e-05 23.2 15.8 1.7 1 1 1 2 2 2 1 Cd27 binding protein (Siva) 2OG-FeII_Oxy_3 PF13640.6 GAX09799.1 - 8.4e-14 52.2 0.0 1.4e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAX09799.1 - 0.16 12.6 0.0 0.49 11.1 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily COX15-CtaA PF02628.15 GAX09800.1 - 0.26 10.3 0.3 0.35 9.9 0.3 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein FAM176 PF14851.6 GAX09800.1 - 1 9.0 3.6 1.4 8.6 2.2 1.8 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 GAX09800.1 - 1.7 6.7 9.4 2.4 6.1 9.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 GAX09800.1 - 1.8 8.5 7.7 0.18 11.8 2.7 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 GAX09800.1 - 7.1 6.3 13.7 0.2 11.4 6.3 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Zw10 PF06248.13 GAX09803.1 - 8.7e-28 97.2 12.4 1.7e-25 89.7 9.9 3.5 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Imm68 PF15583.6 GAX09803.1 - 0.068 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 68 SpoIIID PF12116.8 GAX09803.1 - 0.13 12.4 0.4 11 6.2 0.2 3.2 2 0 0 2 2 2 0 Stage III sporulation protein D Prefoldin_2 PF01920.20 GAX09803.1 - 3.1 7.8 5.9 0.54 10.2 0.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit tRNA-synt_1 PF00133.22 GAX09805.1 - 6.9e-199 662.0 0.0 5e-111 371.8 0.1 3.1 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAX09805.1 - 1.2e-38 132.5 0.1 2.4e-38 131.5 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAX09805.1 - 2.8e-14 52.7 0.2 2.2e-06 26.7 0.1 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAX09805.1 - 4.7e-12 45.8 0.0 4.5e-08 32.8 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 GAX09805.1 - 1.5e-05 25.2 4.1 5.7e-05 23.3 4.1 2.1 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 GAX09805.1 - 0.00011 21.7 0.1 0.15 11.4 0.0 3.7 4 0 0 4 4 4 2 tRNA synthetases class I (C) catalytic domain Ion_trans_N PF08412.10 GAX09805.1 - 0.1 12.2 0.1 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Ion transport protein N-terminal Helicase_C PF00271.31 GAX09806.1 - 4.3e-15 56.0 0.4 1.3e-13 51.3 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX09806.1 - 4.7e-14 52.5 0.0 1.2e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 GAX09806.1 - 8.7e-12 45.6 3.7 8.7e-12 45.6 3.7 2.8 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 GAX09806.1 - 0.0061 16.6 0.0 0.059 13.4 0.0 2.7 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit Ribosomal_S21 PF01165.20 GAX09807.1 - 1.1e-17 63.5 6.7 1.1e-17 63.5 6.7 1.8 1 1 1 2 2 2 1 Ribosomal protein S21 PEHE PF15275.6 GAX09807.1 - 1.6 9.3 6.4 2.1 9.0 6.4 1.2 1 0 0 1 1 1 0 PEHE domain Pribosyltran_N PF13793.6 GAX09808.1 - 0.023 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase DUF5084 PF16894.5 GAX09809.1 - 0.011 16.1 1.9 0.016 15.6 0.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5084) Trp_Tyr_perm PF03222.13 GAX09809.1 - 0.013 14.6 1.2 0.013 14.6 1.2 1.6 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family PP2C PF00481.21 GAX09810.1 - 2.1e-62 211.1 0.0 3e-61 207.3 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX09810.1 - 0.0014 18.3 0.0 0.0041 16.8 0.1 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C Not3 PF04065.15 GAX09811.1 - 3.7e-78 262.1 22.6 3.7e-78 262.1 22.6 2.6 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 GAX09811.1 - 1.7e-44 151.1 8.1 1.7e-44 151.1 8.1 2.8 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family GREB1 PF15782.5 GAX09811.1 - 7.3 3.6 19.3 11 2.9 19.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GST_N_3 PF13417.6 GAX09812.1 - 1.8e-12 47.5 0.0 4.9e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX09812.1 - 5.8e-10 39.4 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX09812.1 - 1.4e-08 34.9 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX09812.1 - 0.00013 21.9 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX09812.1 - 0.002 18.3 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAX09812.1 - 0.014 15.6 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin hGDE_central PF14702.6 GAX09813.1 - 0.23 11.1 9.8 0.043 13.5 4.7 1.9 2 0 0 2 2 2 0 Central domain of human glycogen debranching enzyme DUF3138 PF11336.8 GAX09813.1 - 3.1 6.3 4.9 2.9 6.4 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Tropomyosin_1 PF12718.7 GAX09813.1 - 4.2 7.5 31.6 26 5.0 27.0 3.0 1 1 2 3 3 3 0 Tropomyosin like Vac14_Fab1_bd PF12755.7 GAX09814.1 - 5.3e-33 113.5 2.5 1.2e-31 109.1 0.4 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 GAX09814.1 - 6.2e-32 110.7 0.5 1.5e-31 109.4 0.5 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.22 GAX09814.1 - 2.4e-05 24.2 0.7 0.9 10.0 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 GAX09814.1 - 0.052 13.6 0.8 5.6 7.0 0.0 3.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CtsR_C PF17727.1 GAX09814.1 - 0.12 12.5 0.5 5 7.3 0.0 3.2 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain Sas10 PF09368.10 GAX09816.1 - 1.5e-24 86.2 8.5 1.5e-24 86.2 8.5 2.2 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 GAX09816.1 - 0.098 13.3 0.1 0.098 13.3 0.1 2.9 3 1 0 3 3 3 0 Sas10/Utp3/C1D family PP_kinase_N PF13089.6 GAX09816.1 - 0.3 11.5 2.2 0.66 10.3 0.1 2.5 1 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain AAA_assoc_C PF09821.9 GAX09817.1 - 0.036 14.6 1.6 0.26 11.8 0.0 2.8 2 1 1 3 3 3 0 C-terminal AAA-associated domain WLM PF08325.10 GAX09819.1 - 2.3e-23 83.2 0.0 4e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 GAX09819.1 - 0.0013 17.9 0.9 0.0027 17.0 0.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others BSP PF04450.12 GAX09819.1 - 0.0031 17.4 0.2 0.0046 16.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 GAX09819.1 - 0.19 11.6 2.0 0.46 10.4 2.0 1.6 1 1 0 1 1 1 0 SprT-like family DUF45 PF01863.17 GAX09819.1 - 1.5 8.8 4.0 2.3 8.2 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 HSP70 PF00012.20 GAX09820.1 - 9.6e-268 889.3 12.4 1.1e-267 889.1 12.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX09820.1 - 2.3e-16 59.5 1.5 9.1e-14 51.0 0.3 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GAX09820.1 - 0.00014 21.7 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAX09820.1 - 0.0035 17.7 6.7 5.3 7.5 0.0 4.0 3 3 0 3 3 3 2 Cell division protein FtsA GFRP PF06399.13 GAX09820.1 - 0.12 12.3 0.0 0.62 10.0 0.0 2.1 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) XRN_N PF03159.18 GAX09821.1 - 0.28 10.6 7.6 0.51 9.7 7.6 1.4 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Neur_chan_memb PF02932.16 GAX09821.1 - 0.75 9.8 4.7 1.1 9.3 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 GAX09821.1 - 4.3 7.1 16.5 6.7 6.5 16.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAML PF14963.6 GAX09821.1 - 7.1 6.7 16.4 33 4.5 16.4 1.9 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MCM PF00493.23 GAX09822.1 - 2.3e-94 314.7 0.0 8.6e-84 280.1 0.0 2.8 3 0 0 3 3 3 2 MCM P-loop domain MCM_OB PF17207.3 GAX09822.1 - 3.7e-34 117.3 0.3 7.1e-34 116.4 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX09822.1 - 6.3e-27 93.8 2.0 1.7e-26 92.4 2.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAX09822.1 - 6.7e-07 28.9 0.0 0.00018 21.0 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 GAX09822.1 - 9.7e-07 29.3 4.3 2.3e-06 28.1 1.2 2.8 2 1 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 GAX09822.1 - 3e-06 27.3 0.0 1e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAX09822.1 - 1e-05 25.4 0.0 0.00021 21.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) THOC2_N PF16134.5 GAX09822.1 - 0.034 12.8 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus AAA_16 PF13191.6 GAX09822.1 - 0.089 13.2 3.3 5.9 7.2 0.1 3.8 3 2 1 4 4 4 0 AAA ATPase domain Sigma54_activat PF00158.26 GAX09822.1 - 0.14 11.8 0.0 9.8 5.8 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain BHD_2 PF10404.9 GAX09822.1 - 0.23 12.5 1.6 0.81 10.7 0.5 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Phosphoesterase PF04185.14 GAX09823.1 - 0.02 14.1 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoesterase family DUF2095 PF09868.9 GAX09823.1 - 0.089 12.8 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) IMPa_N_2 PF18650.1 GAX09823.1 - 0.11 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain DUF1541 PF07563.11 GAX09823.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Acetyltransf_10 PF13673.7 GAX09824.1 - 0.0019 18.2 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX09824.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX09824.1 - 0.15 12.5 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glu_synthase PF01645.17 GAX09825.1 - 1.2e-149 498.4 0.3 1.2e-147 491.9 0.2 2.3 2 0 0 2 2 2 2 Conserved region in glutamate synthase GATase_2 PF00310.21 GAX09825.1 - 2.7e-146 487.6 0.0 2.4e-145 484.4 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 GAX09825.1 - 7.7e-105 350.4 0.1 2.4e-104 348.7 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GAX09825.1 - 4.8e-73 244.8 9.4 8.5e-73 244.0 9.4 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 GAX09825.1 - 0.0028 16.7 3.7 0.0067 15.5 3.7 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PBECR4 PF18813.1 GAX09825.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 Pro_isomerase PF00160.21 GAX09827.1 - 1.6e-46 158.4 0.0 1.9e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DNA_pol_A PF00476.20 GAX09828.1 - 7.4e-71 239.2 0.0 1.2e-69 235.1 0.0 2.8 1 1 0 2 2 2 1 DNA polymerase family A SAP PF02037.27 GAX09828.1 - 1.1e-12 47.4 1.6 1.1e-12 47.4 1.6 3.8 3 1 0 3 3 3 2 SAP domain DNA_pol_A_exo1 PF01612.20 GAX09828.1 - 2.8e-09 36.9 0.0 6.8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease LETM1 PF07766.13 GAX09828.1 - 0.0014 18.0 0.5 0.0032 16.8 0.5 1.6 1 0 0 1 1 1 1 LETM1-like protein DUF1800 PF08811.11 GAX09829.1 - 2.4e-37 129.0 0.0 2.3e-23 82.9 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX09829.1 - 8.7e-26 90.9 0.1 1.8e-25 89.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) SnoaL_3 PF13474.6 GAX09830.1 - 1.1e-30 106.3 0.8 1.2e-08 35.2 0.0 3.2 3 0 0 3 3 3 3 SnoaL-like domain CaMKII_AD PF08332.10 GAX09830.1 - 1.5e-30 106.0 0.1 1.4e-11 44.6 0.0 3.2 3 0 0 3 3 3 3 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 GAX09830.1 - 4.2e-26 91.4 2.8 6.3e-08 33.0 0.3 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 GAX09830.1 - 3.4e-15 56.5 0.5 0.00042 20.9 0.0 3.2 3 0 0 3 3 3 3 SnoaL-like domain SnoaL_4 PF13577.6 GAX09830.1 - 9.4e-07 29.0 6.4 0.2 11.8 0.5 5.0 3 2 0 3 3 3 3 SnoaL-like domain GH-E PF14410.6 GAX09830.1 - 0.012 16.0 1.1 3.7 8.0 0.1 2.7 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Anth_synt_I_N PF04715.13 GAX09830.1 - 0.14 12.4 0.1 28 4.9 0.0 2.5 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region FKBP_C PF00254.28 GAX09832.1 - 2.8e-18 66.0 0.0 1.1e-17 64.2 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PDZ_6 PF17820.1 GAX09832.1 - 0.00011 22.0 0.7 0.00038 20.2 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX09832.1 - 0.00025 21.3 0.1 0.0029 17.9 0.0 2.4 2 0 0 2 2 2 1 PDZ domain DUF3394 PF11874.8 GAX09832.1 - 0.003 17.3 1.0 0.014 15.1 0.3 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3394) adh_short PF00106.25 GAX09833.1 - 2.7e-05 23.7 0.0 0.0001 21.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAX09833.1 - 0.17 11.8 1.5 0.44 10.4 1.5 1.7 1 1 0 1 1 1 0 KR domain Pkinase PF00069.25 GAX09834.1 - 2.4e-30 105.8 0.0 5e-30 104.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09834.1 - 1.4e-22 80.2 0.0 3.1e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2439 PF10382.9 GAX09835.1 - 1.8e-08 34.6 0.0 4.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) T2SSC PF11356.8 GAX09835.1 - 0.76 9.7 4.5 0.86 9.5 1.6 2.3 2 0 0 2 2 2 0 Type II secretion system protein C MatE PF01554.18 GAX09836.1 - 1.1e-07 31.7 16.1 0.00017 21.2 0.7 3.0 3 1 0 3 3 3 2 MatE Saf_2TM PF18303.1 GAX09836.1 - 0.035 13.7 5.6 8.3 6.0 1.2 3.4 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Glyco_tranf_2_4 PF13704.6 GAX09837.1 - 2.9e-06 27.7 0.5 2.9e-06 27.7 0.5 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX09837.1 - 0.034 13.8 1.1 0.08 12.6 1.1 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 92 Peptidase_A21 PF03566.13 GAX09837.1 - 1.9 6.7 3.3 2.6 6.2 3.3 1.1 1 0 0 1 1 1 0 Peptidase family A21 NUDIX PF00293.28 GAX09838.1 - 1.6e-17 63.7 0.1 3.1e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain CinA PF02464.17 GAX09838.1 - 1.1e-16 60.8 0.5 8.7e-16 57.9 0.5 2.2 1 1 0 1 1 1 1 Competence-damaged protein zf-NADH-PPase PF09297.11 GAX09838.1 - 9.9e-07 28.3 2.7 2.3e-06 27.1 2.7 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 GAX09838.1 - 0.00073 20.2 0.0 0.0017 19.0 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Tub PF01167.18 GAX09839.1 - 6.1e-47 160.4 0.0 8.3e-46 156.7 0.0 2.4 2 1 0 2 2 2 1 Tub family RdRP PF05183.12 GAX09840.1 - 3.3e-29 102.0 0.0 3e-16 59.2 0.0 2.0 1 1 1 2 2 2 2 RNA dependent RNA polymerase Methyltrans_RNA PF04452.14 GAX09841.1 - 8e-33 113.7 0.0 3.1e-32 111.7 0.0 1.8 1 1 0 1 1 1 1 RNA methyltransferase dUTPase PF00692.19 GAX09842.1 - 5.6e-45 152.2 0.0 6.7e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 dUTPase PC-Esterase PF13839.6 GAX09843.1 - 0.00027 20.8 0.1 0.00038 20.3 0.1 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Ank_2 PF12796.7 GAX09844.1 - 6.4e-16 58.7 0.1 5.9e-08 33.2 0.4 4.3 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX09844.1 - 2.7e-15 54.9 0.9 0.00097 19.4 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 GAX09844.1 - 8e-12 45.2 3.5 5.9e-06 26.5 0.1 5.8 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX09844.1 - 5.3e-11 42.4 1.8 0.00071 19.9 0.1 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 GAX09844.1 - 3e-10 40.4 1.1 2.8e-05 24.6 0.1 4.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) zf-CCHC PF00098.23 GAX09845.1 - 4.7e-24 83.3 20.9 3.4e-08 33.2 3.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 GAX09845.1 - 1.9e-06 27.7 13.1 0.019 14.9 0.6 3.1 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 GAX09845.1 - 9.7e-05 22.0 14.7 0.36 10.6 1.5 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 GAX09845.1 - 0.013 15.1 12.6 0.74 9.6 0.4 3.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Viral_NABP PF05515.11 GAX09845.1 - 0.053 13.4 6.0 0.091 12.6 5.8 1.4 1 1 0 1 1 1 0 Viral nucleic acid binding zf-CCHC_6 PF15288.6 GAX09845.1 - 0.2 11.5 13.0 1.7 8.6 1.0 3.2 3 0 0 3 3 3 0 Zinc knuckle IBR PF01485.21 GAX09845.1 - 0.33 11.2 12.2 2 8.7 6.2 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-CCHC_2 PF13696.6 GAX09845.1 - 0.35 10.7 17.5 1.4 8.8 1.0 3.5 3 1 0 3 3 3 0 Zinc knuckle DZR PF12773.7 GAX09845.1 - 1.1 9.4 14.4 69 3.6 14.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_recom PF13408.6 GAX09845.1 - 1.3 9.6 15.6 1.1 9.8 1.8 2.5 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain FoP_duplication PF13865.6 GAX09845.1 - 1.9 9.1 19.7 0.23 12.0 15.6 1.5 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 zinc_ribbon_2 PF13240.6 GAX09845.1 - 7.4 6.4 11.1 8.8 6.2 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain A_deamin PF02137.18 GAX09846.1 - 9.4e-37 127.2 0.1 3e-34 119.0 0.1 2.2 2 0 0 2 2 2 2 Adenosine-deaminase (editase) domain Coronavirus_5 PF05528.11 GAX09846.1 - 0.023 14.7 0.1 0.07 13.1 0.1 1.7 1 0 0 1 1 1 0 Coronavirus gene 5 protein Phage_pRha PF09669.10 GAX09847.1 - 0.046 14.3 0.0 12 6.5 0.0 2.6 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Peptidase_Mx1 PF15890.5 GAX09847.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase TMEM65 PF10507.9 GAX09848.1 - 5e-44 148.7 6.5 1.2e-43 147.4 6.5 1.7 1 0 0 1 1 1 1 Transmembrane protein 65 GAF_2 PF13185.6 GAX09848.1 - 6.2e-13 49.2 0.0 2.1e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 GAX09848.1 - 1.2e-12 48.6 0.0 2.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 GAX09848.1 - 0.00013 22.3 0.1 0.23 11.8 0.0 3.0 3 0 0 3 3 3 2 GAF domain DUF1043 PF06295.12 GAX09848.1 - 0.45 10.5 2.9 0.8 9.7 0.0 2.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1043) DUF4730 PF15873.5 GAX09848.1 - 6.2 7.2 7.7 0.66 10.3 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) Bromodomain PF00439.25 GAX09849.1 - 3.1e-18 65.6 0.0 6.9e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF309 PF03745.14 GAX09850.1 - 0.048 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF309) DXP_redisom_C PF08436.12 GAX09850.1 - 0.065 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Hist_deacetyl PF00850.19 GAX09851.1 - 7.9e-36 124.1 0.1 1.1e-35 123.6 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 GAX09853.1 - 2e-15 56.9 0.0 2.8e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09853.1 - 2.3e-13 50.0 0.0 3.5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase V-ATPase_G PF03179.15 GAX09854.1 - 1.2e-25 90.0 3.6 1.5e-25 89.8 3.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 GAX09854.1 - 0.0022 17.4 4.9 0.021 14.3 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) PALP PF00291.25 GAX09855.1 - 8.9e-52 176.3 0.1 1.1e-51 176.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_41 PF13844.6 GAX09856.1 - 4.8e-28 97.8 0.3 7.9e-28 97.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_2 PF07719.17 GAX09856.1 - 5.3e-05 23.0 0.1 1.1 9.6 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX09856.1 - 0.00091 18.9 0.0 1.4 8.8 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX09856.1 - 0.0028 17.7 0.2 43 4.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF758 PF05527.11 GAX09856.1 - 0.053 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF758) TPR_11 PF13414.6 GAX09856.1 - 0.054 13.2 0.2 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.6 GAX09856.1 - 0.056 14.3 0.0 47 5.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF2_N PF00176.23 GAX09857.1 - 3.6e-57 193.7 0.0 6e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX09857.1 - 6.2e-18 65.2 0.0 1.9e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX09857.1 - 2.7e-11 43.8 0.0 1.3e-10 41.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAX09857.1 - 9.9e-09 34.8 0.3 2e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAX09857.1 - 0.00038 20.3 0.0 0.00087 19.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Glyco_trans_1_2 PF13524.6 GAX09857.1 - 0.006 16.9 0.0 1.1 9.7 0.0 3.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 SWI2_SNF2 PF18766.1 GAX09857.1 - 0.044 13.5 0.0 0.17 11.5 0.0 2.1 1 1 0 1 1 1 0 SWI2/SNF2 ATPase TspO_MBR PF03073.15 GAX09858.1 - 6.3e-34 116.9 12.9 1e-33 116.2 12.9 1.3 1 0 0 1 1 1 1 TspO/MBR family HSP20 PF00011.21 GAX09859.1 - 0.21 11.7 0.3 0.71 10.1 0.1 1.9 2 0 0 2 2 2 0 Hsp20/alpha crystallin family HA PF03457.14 GAX09860.1 - 2.1e-37 127.2 5.9 7.8e-20 71.0 0.2 2.3 2 0 0 2 2 2 2 Helicase associated domain Arnt_C PF18583.1 GAX09860.1 - 0.049 13.2 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Aminoarabinose transferase C-terminal domain MSC PF09402.10 GAX09862.1 - 0.088 12.2 0.1 0.12 11.8 0.1 1.4 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain HTH_ABP1_N PF18107.1 GAX09863.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain HSF_DNA-bind PF00447.17 GAX09864.1 - 4.1e-29 101.0 1.5 6.8e-29 100.3 1.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DENN PF02141.21 GAX09865.1 - 4.8e-46 157.1 4.1 7.5e-46 156.4 4.1 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAX09865.1 - 4.7e-15 56.1 0.2 1.3e-14 54.7 0.2 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 GAX09865.1 - 1.2e-10 41.2 2.6 3.1e-10 39.9 2.6 1.7 1 0 0 1 1 1 1 dDENN domain PPR PF01535.20 GAX09865.1 - 4.2e-06 26.7 0.5 0.00044 20.3 0.0 2.8 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 GAX09865.1 - 1.8e-05 24.7 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAX09865.1 - 3.2e-05 24.0 0.0 0.0019 18.3 0.0 2.6 1 1 1 2 2 2 2 PPR repeat family PPR_1 PF12854.7 GAX09865.1 - 0.0022 17.6 0.4 0.0093 15.6 0.0 2.2 2 0 0 2 2 2 1 PPR repeat RhlB PF12300.8 GAX09865.1 - 0.046 13.9 0.4 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB TSP_NTD PF17804.1 GAX09865.1 - 0.13 12.6 2.3 0.28 11.4 0.3 2.5 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Methyltransf_25 PF13649.6 GAX09866.1 - 6.7e-07 29.9 0.0 1.2e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX09866.1 - 4e-06 26.7 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAX09866.1 - 1.3e-05 24.9 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 GAX09866.1 - 5.4e-05 23.9 0.0 0.0001 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX09866.1 - 0.00024 21.7 0.0 0.00038 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX09866.1 - 0.0014 18.1 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Endonuclease_5 PF04493.14 GAX09866.1 - 0.0017 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V PCMT PF01135.19 GAX09866.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RVT_2 PF07727.14 GAX09867.1 - 1.7e-40 139.2 0.0 3.1e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX09867.1 - 0.00015 21.6 3.5 0.00046 20.1 3.5 1.9 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 GAX09867.1 - 0.00022 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 GAX09867.1 - 0.0072 16.5 0.1 0.022 15.0 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain LPMO_10 PF03067.15 GAX09868.1 - 3.7e-25 89.7 0.1 6.3e-25 89.0 0.1 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading XRN_M PF17846.1 GAX09869.1 - 3.5e-92 309.7 3.0 9.8e-91 304.9 3.0 2.3 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 GAX09869.1 - 4.1e-91 304.7 0.0 6.9e-91 304.0 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 GAX09869.1 - 3.9e-26 92.0 0.0 7.1e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 GAX09869.1 - 1.4e-17 63.5 0.5 3.9e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 GAX09869.1 - 0.0016 18.6 0.0 0.0069 16.6 0.0 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain DUF2475 PF10629.9 GAX09869.1 - 0.16 12.2 0.7 0.45 10.8 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Topoisom_bac PF01131.20 GAX09870.1 - 8e-102 341.3 0.6 1.6e-101 340.3 0.0 1.8 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 GAX09870.1 - 2.5e-15 56.6 0.0 6.4e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Response_reg PF00072.24 GAX09871.1 - 7.6e-28 96.9 0.0 2.8e-27 95.1 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 GAX09871.1 - 1.3e-13 50.3 0.0 3.9e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Mo25 PF08569.11 GAX09871.1 - 0.007 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Mo25-like Sigma70_r4_2 PF08281.12 GAX09871.1 - 0.0082 15.8 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 GAX09871.1 - 0.018 14.6 0.1 0.045 13.3 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 GAX09871.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding N-glycanase_N PF09112.10 GAX09871.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal HTH_23 PF13384.6 GAX09871.1 - 0.13 12.0 0.3 6.7 6.6 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Siah-Interact_N PF09032.11 GAX09871.1 - 2.2 8.6 5.0 0.63 10.4 1.7 1.8 2 0 0 2 2 2 0 Siah interacting protein, N terminal 60KD_IMP PF02096.20 GAX09872.1 - 1.2e-31 109.9 4.3 1.2e-31 109.9 4.3 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein SNF2_N PF00176.23 GAX09873.1 - 1.5e-48 165.3 0.0 5.1e-48 163.6 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX09873.1 - 2.1e-17 63.5 0.0 1.5e-16 60.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX09873.1 - 2.5e-08 34.1 0.7 9.9e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAX09873.1 - 0.01 15.5 0.6 0.31 10.7 0.0 2.7 2 0 0 2 2 2 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 GAX09873.1 - 0.015 15.5 0.7 1.2 9.4 0.0 3.6 3 1 0 3 3 3 0 AAA domain UIM PF02809.20 GAX09873.1 - 0.029 14.3 0.8 0.21 11.6 0.8 2.6 1 0 0 1 1 1 0 Ubiquitin interaction motif HA PF03457.14 GAX09874.1 - 1.8e-35 121.0 2.6 8e-19 67.7 0.2 2.3 2 0 0 2 2 2 2 Helicase associated domain HTH_26 PF13443.6 GAX09874.1 - 0.062 13.7 0.0 1.3 9.5 0.0 2.8 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain PCI PF01399.27 GAX09875.1 - 2e-13 50.8 0.9 7.7e-13 48.9 0.0 2.4 3 0 0 3 3 3 1 PCI domain RPN5_C PF18098.1 GAX09875.1 - 2.4e-10 40.3 2.0 9.2e-10 38.5 0.5 2.6 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain PPR_2 PF13041.6 GAX09876.1 - 8.6e-35 118.7 12.3 4.4e-07 30.0 0.0 12.5 11 3 2 13 13 13 6 PPR repeat family PPR_3 PF13812.6 GAX09876.1 - 1.2e-29 102.1 0.3 4.9e-09 36.1 0.0 10.2 7 3 4 11 11 11 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX09876.1 - 1.6e-25 88.4 9.4 0.0078 15.9 0.1 13.6 13 2 0 13 13 13 7 PPR repeat PPR_long PF17177.4 GAX09876.1 - 8.9e-13 48.1 6.7 0.0011 18.4 0.0 5.5 2 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP PrkA PF06798.12 GAX09876.1 - 9.7e-05 22.1 2.3 0.035 13.8 0.4 2.9 2 1 0 2 2 2 2 PrkA serine protein kinase C-terminal domain PPR PF01535.20 GAX09876.1 - 0.0014 18.7 46.0 0.13 12.6 0.6 15.5 16 3 0 16 16 16 2 PPR repeat DUF4003 PF13170.6 GAX09876.1 - 0.027 13.8 0.1 0.1 12.0 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4003) RecC_C PF17946.1 GAX09876.1 - 0.032 14.0 2.1 1.3 8.8 0.1 3.7 4 1 1 5 5 5 0 RecC C-terminal domain Rapsyn_N PF10579.9 GAX09876.1 - 0.14 12.3 0.3 1.2 9.3 0.1 2.6 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region AAA_16 PF13191.6 GAX09876.1 - 0.16 12.4 0.2 16 5.9 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain GRIP PF01465.20 GAX09877.1 - 3.1e-11 43.0 0.0 9.9e-11 41.4 0.0 2.0 1 0 0 1 1 1 1 GRIP domain Rho_Binding PF08912.11 GAX09877.1 - 0.018 15.9 3.8 0.018 15.9 3.8 23.5 8 4 18 26 26 26 0 Rho Binding DUF3800 PF12686.7 GAX09877.1 - 0.12 13.0 13.0 1.8e+04 -5.7 12.9 7.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Myb_DNA-bind_7 PF15963.5 GAX09878.1 - 6.5e-22 77.2 3.1 6.5e-22 77.2 3.1 2.9 4 0 0 4 4 4 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 GAX09878.1 - 0.0012 19.0 3.5 0.0012 19.0 0.0 2.9 4 0 0 4 4 4 1 Myb-like DNA-binding domain MgtE PF01769.16 GAX09879.1 - 2.9e-20 72.9 6.4 4.6e-20 72.2 6.4 1.3 1 0 0 1 1 1 1 Divalent cation transporter UPF0242 PF06785.11 GAX09879.1 - 0.22 11.6 2.2 0.37 10.9 2.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 GAX09879.1 - 0.57 10.5 6.9 1.1 9.6 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) PDCD2_C PF04194.13 GAX09880.1 - 3.6e-29 102.1 0.0 1.3e-28 100.2 0.0 1.8 1 1 1 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain RNA_pol_3_Rpc31 PF11705.8 GAX09880.1 - 0.053 13.8 3.7 1.7 8.9 0.8 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 HMG_box PF00505.19 GAX09881.1 - 9.9e-17 61.1 2.1 3.9e-16 59.2 2.1 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX09881.1 - 6.7e-14 52.2 1.3 2.8e-13 50.3 1.3 2.2 1 0 0 1 1 1 1 HMG-box domain LysM PF01476.20 GAX09881.1 - 7.8e-07 29.1 0.0 0.00013 21.9 0.0 2.5 2 0 0 2 2 2 1 LysM domain Acetyltransf_10 PF13673.7 GAX09881.1 - 0.00073 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Imm58 PF15581.6 GAX09881.1 - 0.016 15.3 0.1 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 58 Acetyltransf_7 PF13508.7 GAX09881.1 - 0.057 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MMR_HSR1 PF01926.23 GAX09882.1 - 4.6e-16 58.9 0.1 9.4e-16 57.9 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAX09882.1 - 2.9e-06 27.5 0.0 0.035 14.2 0.0 2.2 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 GAX09882.1 - 0.0002 21.3 0.0 0.0062 16.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 GAX09882.1 - 0.00031 20.3 0.0 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 GAX09882.1 - 0.00043 19.7 0.0 0.00076 18.8 0.0 1.5 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 GAX09882.1 - 0.0011 18.5 0.0 0.0099 15.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 GAX09882.1 - 0.0021 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX09882.1 - 0.0068 16.7 0.1 0.017 15.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 GAX09882.1 - 0.0069 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 GAX09882.1 - 0.026 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_21 PF13304.6 GAX09882.1 - 0.036 13.9 0.8 0.38 10.5 0.5 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 GAX09882.1 - 0.059 13.9 0.1 0.12 12.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Noc2 PF03715.13 GAX09883.1 - 1.1e-72 244.9 4.1 2.2e-72 243.8 2.1 2.2 2 0 0 2 2 2 1 Noc2p family DDHD PF02862.17 GAX09883.1 - 5.8 7.0 17.0 1.3 9.2 2.1 2.4 2 0 0 2 2 2 0 DDHD domain Hist_deacetyl PF00850.19 GAX09884.1 - 9.3e-54 183.0 0.1 1.1e-53 182.7 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF3752 PF12572.8 GAX09885.1 - 5.6e-08 33.4 5.0 5.6e-08 33.4 5.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) Band_3_cyto PF07565.13 GAX09885.1 - 4.7 6.9 10.0 0.25 11.1 4.1 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain ADP_ribosyl_GH PF03747.14 GAX09886.1 - 1.6e-46 159.4 0.1 2.1e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Gly-zipper_Omp PF13488.6 GAX09886.1 - 0.05 13.6 2.5 0.59 10.2 0.6 2.5 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 GAX09886.1 - 0.18 11.6 3.4 0.37 10.6 3.4 1.4 1 0 0 1 1 1 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 GAX09886.1 - 0.37 10.6 4.1 0.18 11.6 1.7 1.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 GAX09886.1 - 0.62 10.0 5.2 0.25 11.2 2.3 1.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain NAD_Gly3P_dh_C PF07479.14 GAX09887.1 - 1.3e-43 148.7 0.1 2e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 GAX09887.1 - 5.7e-41 140.1 0.0 8.3e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 GAX09887.1 - 0.00019 21.9 0.0 0.00037 21.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 GAX09887.1 - 0.0071 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 GAX09887.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.25 GAX09887.1 - 0.041 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Whirly PF08536.11 GAX09888.1 - 0.00086 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Whirly transcription factor LapA_dom PF06305.11 GAX09889.1 - 0.079 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PAF-AH_p_II PF03403.13 GAX09890.1 - 3e-29 101.7 0.0 5.9e-27 94.2 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 GAX09890.1 - 4e-08 32.8 0.4 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX09890.1 - 1.1e-06 28.5 0.1 6.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX09890.1 - 2.2e-06 27.3 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAX09890.1 - 1e-05 26.3 0.9 1e-05 26.3 0.9 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAX09890.1 - 4.6e-05 23.3 0.0 9.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 GAX09890.1 - 0.00037 19.5 0.1 0.0011 17.9 0.1 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 GAX09890.1 - 0.0013 18.4 0.0 0.0032 17.1 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Tannase PF07519.11 GAX09890.1 - 0.034 13.1 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Chlorophyllase PF07224.11 GAX09890.1 - 0.17 10.9 0.1 1.1 8.2 0.0 2.2 3 0 0 3 3 3 0 Chlorophyllase Chromo PF00385.24 GAX09891.1 - 0.12 12.3 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain SNF2_N PF00176.23 GAX09892.1 - 8e-58 195.8 0.0 1.7e-57 194.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX09892.1 - 5.5e-17 62.1 0.0 1.2e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GAX09892.1 - 1.1e-05 24.7 0.0 6.1e-05 22.3 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 GAX09892.1 - 0.001 19.1 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DOT1 PF08123.13 GAX09894.1 - 2.5e-09 37.0 0.0 5.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PP_kinase_C PF13090.6 GAX09894.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 DUF3493 PF11998.8 GAX09895.1 - 2e-13 50.3 1.0 3.3e-13 49.6 1.0 1.4 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 PIG-F PF06699.11 GAX09896.1 - 7.3e-06 26.3 13.9 2.6e-05 24.5 13.9 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F ENTH PF01417.20 GAX09897.1 - 2e-30 105.4 0.0 3.1e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAX09897.1 - 0.29 10.1 0.0 0.29 10.1 0.0 1.6 2 0 0 2 2 2 0 ANTH domain DAO PF01266.24 GAX09898.1 - 1.3e-30 107.2 0.1 1.5e-30 107.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX09898.1 - 9.7e-05 21.6 0.0 0.00017 20.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 GAX09898.1 - 0.00039 20.8 0.0 0.00064 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.14 GAX09898.1 - 0.013 14.2 0.2 0.057 12.1 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 GAX09898.1 - 0.02 14.2 0.0 0.068 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX09898.1 - 0.022 15.3 0.0 0.078 13.6 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX09898.1 - 0.03 13.6 0.3 0.067 12.4 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAX09898.1 - 0.092 12.0 1.3 0.19 11.0 0.3 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAX09898.1 - 0.097 12.0 0.4 1.6 8.0 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AP_endonuc_2 PF01261.24 GAX09898.1 - 0.1 12.0 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel 3HCDH_N PF02737.18 GAX09898.1 - 0.12 12.2 0.2 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 GAX09898.1 - 0.13 12.5 0.8 0.32 11.3 0.8 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 GAX09898.1 - 0.15 11.4 0.0 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RPAP1_N PF08621.10 GAX09899.1 - 6e-10 38.7 1.5 1.5e-09 37.5 1.5 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal PRIMA1 PF16101.5 GAX09899.1 - 0.72 9.9 7.2 1.6 8.8 7.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PMSR PF01625.21 GAX09900.1 - 2.3e-14 53.9 8.7 7.7e-13 48.9 8.7 3.1 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 GAX09900.1 - 0.00025 21.3 0.0 0.00066 20.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1413 PF07205.11 GAX09900.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) ABC_tran PF00005.27 GAX09901.1 - 1.3e-38 132.7 0.0 2e-19 70.4 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAX09901.1 - 4.1e-13 49.8 1.3 0.026 14.3 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX09901.1 - 4.7e-11 42.5 0.0 0.0014 18.1 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAX09901.1 - 7.7e-08 32.4 0.1 0.0024 17.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAX09901.1 - 3.3e-07 30.0 0.2 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX09901.1 - 4.1e-06 27.4 6.9 0.016 15.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 GAX09901.1 - 1e-05 25.5 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Roc PF08477.13 GAX09901.1 - 2.3e-05 24.6 0.2 0.33 11.2 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAX09901.1 - 3.8e-05 23.7 1.1 0.091 12.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAX09901.1 - 4.5e-05 23.8 0.0 0.067 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX09901.1 - 5.6e-05 23.0 1.7 0.38 10.4 0.1 3.3 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 GAX09901.1 - 6.9e-05 23.1 0.2 0.19 12.0 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_15 PF13175.6 GAX09901.1 - 7.1e-05 22.7 0.1 0.47 10.1 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 GAX09901.1 - 0.00011 22.7 0.0 1 9.7 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain PduV-EutP PF10662.9 GAX09901.1 - 0.00015 21.5 0.1 0.67 9.7 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 GAX09901.1 - 0.00028 20.9 0.2 0.36 10.9 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE 4HB PF17947.1 GAX09901.1 - 0.0003 20.8 0.0 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 Four helical bundle domain NB-ARC PF00931.22 GAX09901.1 - 0.00045 19.5 0.3 0.2 10.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 GAX09901.1 - 0.00068 20.1 0.1 1.8 9.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 GAX09901.1 - 0.0014 18.1 0.4 0.045 13.2 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_30 PF13604.6 GAX09901.1 - 0.0016 18.2 0.1 2.3 7.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAX09901.1 - 0.0017 18.9 0.0 5.7 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 GAX09901.1 - 0.0023 18.1 0.6 0.3 11.1 0.6 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_14 PF13173.6 GAX09901.1 - 0.0038 17.3 0.0 3 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 GAX09901.1 - 0.0039 15.9 0.8 0.4 9.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 GAX09901.1 - 0.0041 17.1 0.5 2.6 7.9 0.1 2.8 3 0 0 3 3 2 1 NTPase ATPase_2 PF01637.18 GAX09901.1 - 0.0047 16.9 0.1 1.7 8.5 0.0 2.7 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 GAX09901.1 - 0.0051 16.5 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF3584 PF12128.8 GAX09901.1 - 0.0069 14.0 3.6 0.065 10.7 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) RNA_helicase PF00910.22 GAX09901.1 - 0.011 16.1 0.3 6 7.3 0.0 2.9 2 1 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 GAX09901.1 - 0.013 14.8 0.1 5.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 GAX09901.1 - 0.013 14.7 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 GAX09901.1 - 0.017 14.7 0.8 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 GAX09901.1 - 0.02 14.4 2.4 0.22 11.0 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX09901.1 - 0.029 14.4 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 GAX09901.1 - 0.03 13.9 2.1 1.7 8.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 GAX09901.1 - 0.032 13.8 0.2 7.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Ras family DUF815 PF05673.13 GAX09901.1 - 0.036 13.2 0.1 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.14 GAX09901.1 - 0.038 13.9 0.4 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 GAX09901.1 - 0.052 13.7 0.3 4.3 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 GAX09901.1 - 0.053 13.8 0.0 0.95 9.7 0.0 3.1 3 1 0 3 3 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 GAX09901.1 - 0.056 13.1 2.4 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DLIC PF05783.11 GAX09901.1 - 0.067 12.0 0.1 1.8 7.3 0.1 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_25 PF13481.6 GAX09901.1 - 0.083 12.4 0.3 6.7 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 GAX09901.1 - 0.11 12.3 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein RuvB_N PF05496.12 GAX09901.1 - 0.13 12.0 0.4 20 4.9 0.1 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX09901.1 - 0.18 11.8 0.2 33 4.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 GAX09901.1 - 0.3 9.8 0.9 6.4 5.5 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_19 PF13245.6 GAX09901.1 - 0.32 11.3 1.0 4 7.8 0.2 2.3 2 0 0 2 2 2 0 AAA domain Na_H_Exchanger PF00999.21 GAX09902.1 - 1.6e-34 119.3 23.6 3e-34 118.4 23.6 1.4 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2207 PF09972.9 GAX09902.1 - 0.03 13.1 0.8 0.068 11.9 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4239 PF14023.6 GAX09904.1 - 2e-53 181.3 0.5 3.3e-53 180.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Mito_carr PF00153.27 GAX09905.1 - 6e-65 215.2 4.9 2.8e-21 75.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mo25 PF08569.11 GAX09906.1 - 5e-65 220.0 0.2 1.2e-64 218.8 0.2 1.5 1 1 0 1 1 1 1 Mo25-like Zn-C2H2_12 PF18112.1 GAX09906.1 - 0.97 10.0 3.2 1.9 9.0 3.2 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Carbam_trans_C PF16861.5 GAX09908.1 - 1.9e-62 209.8 0.0 1.1e-61 207.4 0.0 2.1 2 0 0 2 2 2 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 GAX09908.1 - 8.1e-27 94.8 0.6 3.1e-14 53.4 0.0 3.4 2 1 0 2 2 2 2 Carbamoyltransferase N-terminus Ribosomal_S15 PF00312.22 GAX09910.1 - 2e-30 104.8 1.4 4.9e-30 103.6 1.4 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 FTCD_C PF04961.12 GAX09910.1 - 0.0056 16.5 0.4 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Formiminotransferase-cyclodeaminase Sec20 PF03908.13 GAX09910.1 - 0.062 13.2 1.5 0.11 12.4 0.3 2.0 1 1 1 2 2 2 0 Sec20 VWA PF00092.28 GAX09910.1 - 0.064 13.5 0.7 0.093 13.0 0.7 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Eapp_C PF10238.9 GAX09911.1 - 0.0016 18.6 2.8 0.0016 18.6 2.8 2.4 2 0 0 2 2 2 1 E2F-associated phosphoprotein F-box PF00646.33 GAX09911.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 GAX09911.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like HisKA PF00512.25 GAX09911.1 - 1.6 8.8 4.5 3.9 7.6 0.1 3.4 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Sec1 PF00995.23 GAX09912.1 - 2.5e-107 360.5 0.3 2.9e-107 360.3 0.3 1.0 1 0 0 1 1 1 1 Sec1 family Leu_Phe_trans PF03588.14 GAX09913.1 - 2.9e-26 92.0 0.0 9.3e-26 90.3 0.0 1.7 1 1 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase DXP_reductoisom PF02670.16 GAX09914.1 - 7e-41 140.0 2.4 1.2e-40 139.2 2.4 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 GAX09914.1 - 5.1e-36 123.4 0.0 8.3e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 GAX09914.1 - 2.2e-35 120.6 0.0 5.5e-35 119.4 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain CDP-OH_P_transf PF01066.21 GAX09915.1 - 8.6e-06 26.4 0.2 8.6e-06 26.4 0.2 2.8 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase 6PF2K PF01591.18 GAX09916.1 - 4.2e-57 193.0 0.1 2.4e-31 108.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAX09916.1 - 7e-16 58.5 0.0 1.7e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAX09916.1 - 2.8e-05 24.3 0.3 0.00029 21.0 0.3 2.5 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 GAX09916.1 - 0.0018 17.8 0.1 0.0068 15.9 0.0 2.0 2 0 0 2 2 2 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 GAX09916.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ANAPC4_WD40 PF12894.7 GAX09918.1 - 2.1e-07 31.1 0.0 3.6e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX09918.1 - 4.5e-07 30.5 1.9 0.0015 19.3 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ATP-synt_C PF00137.21 GAX09920.1 - 2.1e-26 92.1 23.1 3.3e-16 59.4 8.9 2.3 2 0 0 2 2 2 2 ATP synthase subunit C FF PF01846.19 GAX09921.1 - 4.4e-20 71.6 18.2 1.2e-07 31.8 2.0 5.6 5 1 0 5 5 5 4 FF domain WW PF00397.26 GAX09921.1 - 3.2e-09 36.7 16.7 2.6e-07 30.6 1.9 3.5 2 1 0 2 2 2 2 WW domain PAP_assoc PF03828.19 GAX09922.1 - 0.00069 19.8 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAX09922.1 - 0.02 15.2 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HCO3_cotransp PF00955.21 GAX09923.1 - 2.6e-108 363.1 17.5 3.7e-62 210.8 6.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family Indigoidine_A PF04227.12 GAX09924.1 - 1.9e-111 372.1 1.2 2.7e-111 371.6 1.2 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 GAX09924.1 - 3.5e-33 115.2 0.0 8.2e-33 114.0 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase YcaO PF02624.16 GAX09924.1 - 0.26 10.5 1.9 1.3 8.3 0.0 2.6 3 0 0 3 3 3 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding His_Phos_1 PF00300.22 GAX09925.1 - 3.3e-09 36.7 0.0 0.0037 17.0 0.0 3.2 2 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) DNA_mis_repair PF01119.19 GAX09925.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain Cyclin PF08613.11 GAX09926.1 - 4.2e-05 24.0 0.0 8.7e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAX09926.1 - 0.00022 21.0 0.1 0.00042 20.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 GAX09927.1 - 6.3e-45 153.6 0.1 2.2e-44 151.8 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09927.1 - 2.8e-43 148.1 0.1 3.9e-43 147.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YukC PF10140.9 GAX09927.1 - 0.0011 17.8 0.1 0.0017 17.3 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC PIP49_C PF12260.8 GAX09927.1 - 0.035 13.7 0.0 0.035 13.7 0.0 1.9 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 B2 PF11473.8 GAX09927.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein B2 adh_short PF00106.25 GAX09928.1 - 5.1e-28 97.9 0.2 7.5e-28 97.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX09928.1 - 3.3e-24 85.7 0.1 4.5e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAX09928.1 - 4.2e-05 23.1 0.0 6.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX09928.1 - 0.00056 19.9 0.2 0.00074 19.5 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAX09928.1 - 0.00065 19.6 0.3 0.002 18.0 0.1 1.9 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 GAX09928.1 - 0.011 14.8 0.3 0.026 13.7 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain ThiF PF00899.21 GAX09928.1 - 0.011 15.1 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 GAX09928.1 - 0.02 14.3 0.0 0.05 13.0 0.0 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAX09928.1 - 0.037 14.0 0.2 0.091 12.7 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DFP PF04127.15 GAX09928.1 - 0.14 12.0 0.4 0.73 9.6 0.1 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ABC_tran PF00005.27 GAX09929.1 - 1.6e-50 171.2 0.1 2e-28 99.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAX09929.1 - 6.1e-45 154.0 18.7 1.7e-24 86.9 6.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAX09929.1 - 1.9e-13 50.4 0.5 1.4e-06 27.9 0.1 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX09929.1 - 1.1e-06 29.0 1.4 0.018 15.3 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAX09929.1 - 4.2e-06 26.8 0.8 0.27 11.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAX09929.1 - 3.5e-05 23.8 0.6 0.28 11.3 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX09929.1 - 4.1e-05 23.2 2.1 0.17 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAX09929.1 - 0.0014 19.0 6.6 0.36 11.2 0.4 3.3 3 2 0 3 3 2 2 AAA ATPase domain DUF815 PF05673.13 GAX09929.1 - 0.0031 16.7 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Dynamin_N PF00350.23 GAX09929.1 - 0.0033 17.5 2.6 0.057 13.5 0.2 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 GAX09929.1 - 0.0078 16.3 3.2 1.2 9.2 0.2 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 GAX09929.1 - 0.01 15.8 0.8 3 7.7 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 GAX09929.1 - 0.013 15.0 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 GAX09929.1 - 0.034 14.6 0.7 11 6.4 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAX09929.1 - 0.041 13.6 1.2 3.3 7.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX09929.1 - 0.044 13.1 4.5 4.3 6.6 0.3 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 GAX09929.1 - 0.044 13.1 0.3 5.3 6.3 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 GAX09929.1 - 0.056 13.0 0.4 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 GAX09929.1 - 0.084 13.4 1.8 5.4 7.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 GAX09929.1 - 0.095 11.6 0.3 44 2.8 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.6 GAX09929.1 - 0.12 12.9 0.0 2.6 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 GAX09929.1 - 0.14 11.9 0.2 4.8 6.8 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 GAX09929.1 - 0.14 11.1 0.6 5.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 GAX09929.1 - 0.21 10.7 0.4 15 4.6 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain Pox_A32 PF04665.12 GAX09929.1 - 0.23 10.9 0.3 6 6.3 0.3 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein SMC_N PF02463.19 GAX09930.1 - 2e-71 239.9 26.0 5.8e-70 235.1 26.0 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAX09930.1 - 2.1e-24 86.1 0.0 7.4e-24 84.3 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 GAX09930.1 - 1.4e-13 51.8 9.2 1.4e-13 51.8 9.2 7.1 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 GAX09930.1 - 1.9e-13 50.9 0.0 7.4e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAX09930.1 - 5.8e-12 46.0 19.7 5.8e-12 46.0 19.7 4.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAX09930.1 - 8.9e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX09930.1 - 0.042 14.4 0.0 0.042 14.4 0.0 5.3 5 1 0 5 5 5 0 ABC transporter DUF16 PF01519.16 GAX09930.1 - 0.22 12.1 0.1 0.22 12.1 0.1 8.0 5 4 1 6 6 6 0 Protein of unknown function DUF16 Flu_M1_C PF08289.11 GAX09930.1 - 2 8.7 7.5 1.6 9.0 2.0 3.5 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain Filament PF00038.21 GAX09930.1 - 3 7.3 101.6 0.028 14.0 16.2 6.1 2 2 4 6 6 6 0 Intermediate filament protein Adenine_glyco PF03352.13 GAX09931.1 - 5.2e-60 202.2 0.0 8.2e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 Methyladenine glycosylase LPD3 PF18798.1 GAX09931.1 - 0.041 14.1 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 Methyltransf_11 PF08241.12 GAX09932.1 - 2e-23 82.9 0.0 3.4e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX09932.1 - 5e-23 81.6 0.0 9.8e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX09932.1 - 2.2e-21 76.2 0.0 3.6e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX09932.1 - 1.8e-17 63.7 0.0 3e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX09932.1 - 4.6e-16 59.4 0.0 9.9e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX09932.1 - 1e-15 57.7 0.0 2.5e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 GAX09932.1 - 7e-12 45.2 0.0 9.4e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 GAX09932.1 - 7e-10 38.1 0.0 9.4e-10 37.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 GAX09932.1 - 1.8e-06 27.9 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 GAX09932.1 - 3.5e-05 24.0 0.0 0.0002 21.5 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 GAX09932.1 - 0.0022 17.6 0.0 0.0046 16.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 GAX09932.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_24 PF13578.6 GAX09932.1 - 0.0076 17.3 0.0 0.013 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAX09932.1 - 0.0083 15.6 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 GAX09932.1 - 0.0095 15.4 0.0 0.023 14.1 0.0 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 GAX09932.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.12 GAX09932.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.26 GAX09932.1 - 0.034 14.1 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAS PF03059.16 GAX09932.1 - 0.068 12.5 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_20 PF12147.8 GAX09932.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Hydrolase_4 PF12146.8 GAX09933.1 - 5.8e-13 48.7 0.1 1.7e-08 34.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX09933.1 - 2.6e-08 34.8 0.7 1.2e-06 29.3 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX09933.1 - 5e-08 32.9 0.0 0.00023 20.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 GAX09933.1 - 0.00011 21.0 0.0 0.042 12.5 0.0 2.4 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 GAX09933.1 - 0.00027 20.9 0.0 0.00093 19.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX09933.1 - 0.00048 19.7 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAX09933.1 - 0.007 16.2 0.0 0.64 9.8 0.0 3.1 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 GAX09933.1 - 0.017 15.1 0.0 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 GAX09933.1 - 0.018 14.6 0.0 2.6 7.5 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family Peptidase_S28 PF05577.12 GAX09933.1 - 0.052 12.3 0.0 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Serine carboxypeptidase S28 FSH1 PF03959.13 GAX09933.1 - 0.062 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 GAX09933.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain UDPG_MGDP_dh_N PF03721.14 GAX09934.1 - 7.9e-60 201.6 0.2 1.2e-59 201.0 0.2 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 GAX09934.1 - 1e-32 112.7 0.3 7.2e-32 109.9 0.1 2.4 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 GAX09934.1 - 9.3e-31 105.9 0.0 2e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 GAX09934.1 - 0.0018 18.5 0.1 0.0061 16.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX09934.1 - 0.054 13.8 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LRV_FeS PF05484.11 GAX09934.1 - 0.074 13.1 0.1 17 5.5 0.0 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster Peptidase_M50 PF02163.22 GAX09935.1 - 1.2e-05 24.7 5.0 0.043 13.1 2.3 3.2 2 1 0 2 2 2 2 Peptidase family M50 Prismane PF03063.20 GAX09936.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family IBD PF10416.9 GAX09937.1 - 0.064 13.3 1.0 11 6.1 0.4 2.5 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD CENP-O PF09496.10 GAX09938.1 - 0.028 14.4 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component HSF_DNA-bind PF00447.17 GAX09941.1 - 1.2e-19 70.7 0.0 3.4e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding 2OG-FeII_Oxy_3 PF13640.6 GAX09942.1 - 3.6e-10 40.6 0.0 6.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PUNUT PF16913.5 GAX09942.1 - 0.038 13.2 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport Ank_4 PF13637.6 GAX09945.1 - 1.1e-09 38.6 0.5 1.8e-06 28.4 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX09945.1 - 4.1e-09 36.9 0.0 5.1e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX09945.1 - 3.7e-08 33.5 0.2 1.2e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX09945.1 - 2.5e-06 27.7 0.0 0.003 17.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 GAX09945.1 - 1.2e-05 26.1 0.0 2.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_3 PF13606.6 GAX09945.1 - 0.0001 22.5 0.0 0.42 11.3 0.0 4.2 3 0 0 3 3 3 1 Ankyrin repeat CEBP_ZZ PF16366.5 GAX09945.1 - 0.0091 16.2 2.7 0.0091 16.2 2.7 2.6 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_5 PF14634.6 GAX09945.1 - 0.012 15.5 6.0 0.051 13.5 6.0 2.2 1 0 0 1 1 1 0 zinc-RING finger domain FGGY_N PF00370.21 GAX09947.1 - 1e-05 25.2 0.0 0.00016 21.3 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Headcase PF16002.5 GAX09947.1 - 0.043 13.3 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Headcase protein FGGY_C PF02782.16 GAX09947.1 - 0.045 13.5 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain RNase_T PF00929.24 GAX09948.1 - 4.7e-06 27.2 0.2 8.6e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Exonuclease zf-CCCH_4 PF18044.1 GAX09948.1 - 0.00017 21.3 0.9 0.00031 20.5 0.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 GAX09948.1 - 0.00088 19.1 2.1 0.002 18.0 2.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 GAX09948.1 - 0.0099 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GAX09948.1 - 0.03 14.4 3.2 0.075 13.1 3.2 1.7 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 GAX09948.1 - 0.29 11.7 2.0 0.58 10.7 2.0 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GAX09948.1 - 0.98 10.1 5.5 0.23 12.2 0.3 2.7 3 0 0 3 3 3 0 Torus domain Beta_helix PF13229.6 GAX09949.1 - 0.0002 21.2 2.3 0.0027 17.6 2.3 2.1 1 1 0 1 1 1 1 Right handed beta helix region Pkinase PF00069.25 GAX09950.1 - 4e-34 118.2 1.4 4.5e-20 72.1 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX09950.1 - 5.7e-12 45.5 0.2 9.8e-05 21.8 0.1 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase DUF1542 PF07564.11 GAX09950.1 - 1.2 9.3 5.8 2.1 8.5 4.3 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) Actin PF00022.19 GAX09951.1 - 2.3e-111 372.3 0.0 1.3e-110 369.8 0.0 1.8 1 1 0 1 1 1 1 Actin EcoRII-C PF09019.11 GAX09951.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 EcoRII C terminal HSF_DNA-bind PF00447.17 GAX09952.1 - 6.7e-11 42.7 0.8 1.2e-10 41.8 0.8 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 GAX09953.1 - 2e-20 73.2 2.5 2.7e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 HSF-type DNA-binding Methyltr_RsmB-F PF01189.17 GAX09953.1 - 0.19 11.4 0.0 18 4.9 0.0 2.2 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Ribosomal_S18 PF01084.20 GAX09954.1 - 3e-14 53.0 1.3 4.2e-14 52.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 CASP_C PF08172.12 GAX09955.1 - 2e-53 181.3 4.2 2e-53 181.3 4.2 4.0 3 1 0 3 3 3 1 CASP C terminal DUF1664 PF07889.12 GAX09955.1 - 0.0024 17.9 0.5 0.0024 17.9 0.5 6.7 4 1 3 7 7 7 2 Protein of unknown function (DUF1664) Syntaxin-18_N PF10496.9 GAX09955.1 - 0.0078 16.4 0.4 0.0078 16.4 0.4 3.2 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Cortex-I_coil PF09304.10 GAX09955.1 - 0.01 16.1 4.5 0.01 16.1 4.5 6.6 4 1 4 8 8 8 1 Cortexillin I, coiled coil HEAT_2 PF13646.6 GAX09956.1 - 0.26 11.7 6.4 0.51 10.7 0.5 3.4 3 1 0 3 3 3 0 HEAT repeats Na_Pi_cotrans PF02690.15 GAX09957.1 - 1.6e-37 128.7 23.3 3.7e-19 69.2 7.3 3.0 3 0 0 3 3 3 2 Na+/Pi-cotransporter Pep3_Vps18 PF05131.14 GAX09959.1 - 4e-14 52.7 0.1 6e-13 48.9 0.1 2.3 1 1 0 1 1 1 1 Pep3/Vps18/deep orange family DUF5082 PF16888.5 GAX09959.1 - 0.18 12.1 0.4 5.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) zf-Tim10_DDP PF02953.15 GAX09960.1 - 3.1e-15 55.6 6.8 4.3e-15 55.1 6.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF775 PF05603.12 GAX09960.1 - 0.034 13.7 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Mitoc_L55 PF09776.9 GAX09960.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Gluconate_2-dh3 PF13618.6 GAX09960.1 - 0.088 13.0 0.6 0.17 12.1 0.2 1.6 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Calici_MSP PF05752.11 GAX09960.1 - 0.11 12.3 4.6 1.7 8.4 1.1 2.0 1 1 1 2 2 2 0 Calicivirus minor structural protein 7tm_3 PF00003.22 GAX09961.1 - 6.2e-33 114.5 12.8 9.8e-33 113.8 12.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 5_nucleotid_C PF02872.18 GAX09961.1 - 5.9e-23 81.8 0.0 1.9e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain IPP-2 PF04979.14 GAX09961.1 - 0.85 10.4 4.8 1.4 9.7 4.8 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) AARP2CN PF08142.12 GAX09962.1 - 2e-27 95.1 0.0 8.5e-27 93.1 0.0 2.2 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RIBIOP_C PF04950.12 GAX09962.1 - 4.5e-26 91.9 1.1 1.2e-25 90.6 0.0 2.2 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AAA_22 PF13401.6 GAX09962.1 - 1.5e-05 25.2 0.0 4.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 GAX09962.1 - 1.7e-05 24.4 0.3 0.0012 18.4 0.0 2.7 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 GAX09962.1 - 8.6e-05 22.7 0.0 0.00026 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX09962.1 - 0.00019 21.9 0.0 0.00064 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GAX09962.1 - 0.0002 21.1 0.5 0.0009 19.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAX09962.1 - 0.00051 20.1 1.7 0.00082 19.4 0.2 2.2 2 1 0 2 2 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAX09962.1 - 0.00076 20.0 0.0 0.004 17.7 0.0 2.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAX09962.1 - 0.0033 17.3 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_19 PF13245.6 GAX09962.1 - 0.0037 17.6 0.3 0.02 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX09962.1 - 0.0041 17.1 0.1 0.0096 15.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) cobW PF02492.19 GAX09962.1 - 0.0043 16.7 0.1 0.0085 15.7 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 GAX09962.1 - 0.0048 17.4 0.2 0.0048 17.4 0.2 3.2 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 GAX09962.1 - 0.0055 17.1 0.1 0.013 15.9 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GAX09962.1 - 0.007 16.1 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 GAX09962.1 - 0.0072 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 GAX09962.1 - 0.0083 16.1 0.8 0.02 14.8 0.8 1.7 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.22 GAX09962.1 - 0.012 16.0 0.3 0.055 13.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 GAX09962.1 - 0.013 15.0 1.2 0.26 10.8 0.1 2.3 1 1 1 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 GAX09962.1 - 0.019 14.9 1.5 0.041 13.8 0.0 2.3 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAX09962.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 GAX09962.1 - 0.034 13.9 0.1 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 GAX09962.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 GAX09962.1 - 0.051 13.6 1.2 0.51 10.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain KTI12 PF08433.10 GAX09962.1 - 0.058 12.8 0.6 0.4 10.1 0.1 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PduV-EutP PF10662.9 GAX09962.1 - 0.063 13.0 0.1 0.3 10.8 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 GAX09962.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 GAX09962.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 GAX09962.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 GAX09962.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Adeno_IVa2 PF02456.15 GAX09962.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_17 PF13207.6 GAX09962.1 - 0.24 11.8 0.0 0.24 11.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain Ribosomal_L5e PF17144.4 GAX09964.1 - 4.3e-81 270.7 1.6 4.3e-81 270.7 1.6 1.8 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GAX09964.1 - 4.3e-30 104.5 3.2 4.3e-30 104.5 3.2 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region PAZ PF02170.22 GAX09964.1 - 0.0041 16.9 1.4 0.0057 16.5 0.0 1.9 2 0 0 2 2 2 1 PAZ domain TMEM18 PF14770.6 GAX09965.1 - 6.6e-37 126.1 3.2 8.8e-37 125.7 3.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 Macro PF01661.21 GAX09966.1 - 3.8e-15 56.0 0.0 7.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Macro domain DNA_methylase PF00145.17 GAX09967.1 - 1.6e-32 113.2 0.0 1.8e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNA_repr_REX1B PF14966.6 GAX09968.1 - 6.6e-26 90.8 2.3 6.6e-26 90.8 2.3 2.1 3 0 0 3 3 3 1 DNA repair REX1-B DUF1690 PF07956.11 GAX09968.1 - 0.0049 17.3 12.6 0.034 14.6 1.8 2.2 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) RHH_4 PF13467.6 GAX09968.1 - 0.041 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix domain K-box PF01486.17 GAX09968.1 - 0.21 11.8 13.5 0.42 10.8 3.7 3.0 2 1 0 2 2 2 0 K-box region YjeJ PF15922.5 GAX09968.1 - 0.45 9.7 11.8 0.4 9.9 4.9 2.0 1 1 1 2 2 2 0 YjeJ-like Rpn3_C PF08375.11 GAX09969.1 - 8.8e-24 83.7 0.7 8.8e-24 83.7 0.7 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 GAX09969.1 - 4.2e-17 62.6 0.1 2.2e-14 53.8 0.0 3.0 2 0 0 2 2 2 2 PCI domain Ion_trans_2 PF07885.16 GAX09969.1 - 2.2e-12 46.7 18.3 2.1e-08 34.0 1.4 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 GAX09969.1 - 0.016 14.5 6.1 0.033 13.4 0.1 2.3 2 0 0 2 2 2 0 Ion transport protein RRM_1 PF00076.22 GAX09970.1 - 1.1e-54 182.2 0.2 3.7e-20 71.5 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX09970.1 - 6e-08 32.7 0.1 0.021 14.9 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 GAX09970.1 - 0.0014 18.6 0.1 0.27 11.3 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nab6_mRNP_bdg PF10567.9 GAX09970.1 - 0.081 12.4 0.0 2.6 7.4 0.0 2.3 1 1 1 2 2 2 0 RNA-recognition motif PHM7_cyt PF14703.6 GAX09970.1 - 0.1 12.8 0.6 8.8 6.5 0.1 3.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter LPMO_10 PF03067.15 GAX09971.1 - 9.4e-30 104.7 0.2 1.2e-29 104.4 0.2 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Toxin_7 PF05980.12 GAX09971.1 - 0.023 15.0 10.4 0.068 13.4 10.4 1.9 1 0 0 1 1 1 0 Toxin 7 Toxin_12 PF07740.12 GAX09971.1 - 0.53 11.0 7.5 1.2 9.9 7.5 1.6 1 0 0 1 1 1 0 Ion channel inhibitory toxin Toxin_35 PF10530.9 GAX09971.1 - 0.6 10.1 5.9 0.52 10.3 2.6 2.3 2 0 0 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold TALPID3 PF15324.6 GAX09971.1 - 4.9 4.7 4.5 6.6 4.3 4.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target HSF_DNA-bind PF00447.17 GAX09972.1 - 2e-20 73.2 1.5 3.1e-20 72.6 0.5 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Tup_N PF08581.10 GAX09972.1 - 0.052 13.9 0.8 0.052 13.9 0.8 1.7 1 1 0 1 1 1 0 Tup N-terminal DUF1326 PF07040.11 GAX09972.1 - 0.14 12.2 0.2 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) CRAL_TRIO PF00650.20 GAX09973.1 - 6.8e-20 71.4 0.0 1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain PfkB PF00294.24 GAX09974.1 - 5.5e-24 85.0 0.0 2.2e-23 83.0 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase GvpL_GvpF PF06386.11 GAX09974.1 - 0.054 13.4 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF5544 PF17698.1 GAX09974.1 - 0.1 12.7 0.6 1.7 8.8 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5544) TIM PF00121.18 GAX09975.1 - 4.6e-84 281.6 0.0 5.7e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase SGL PF08450.12 GAX09975.1 - 1e-30 107.1 0.0 1.5e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NAD_binding_2 PF03446.15 GAX09977.1 - 1.1e-28 100.4 0.6 2e-28 99.6 0.6 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAX09977.1 - 8.5e-24 84.1 0.1 2e-23 82.9 0.1 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAX09977.1 - 1e-06 29.2 0.2 3.3e-06 27.6 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GAX09977.1 - 0.0001 22.4 0.3 0.0003 20.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SGL PF08450.12 GAX09977.1 - 0.096 12.2 0.0 0.19 11.3 0.0 1.4 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DHQ_synthase PF01761.20 GAX09978.1 - 4.3e-60 203.1 0.0 6.5e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 GAX09978.1 - 5.4e-10 39.4 0.0 2.6e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 GAX09978.1 - 1.5e-05 24.0 0.0 0.0002 20.3 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase TPR_2 PF07719.17 GAX09979.1 - 6.9e-32 107.0 38.9 0.00017 21.4 0.0 15.6 17 0 0 17 17 15 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAX09979.1 - 3.1e-31 107.5 29.0 1e-08 35.3 0.2 10.0 9 2 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAX09979.1 - 6e-26 90.8 35.3 0.00044 20.8 0.0 10.6 8 2 2 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAX09979.1 - 5.6e-25 85.4 17.4 0.003 17.6 0.0 12.9 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX09979.1 - 8.8e-25 85.5 37.2 0.00012 21.7 0.6 12.3 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAX09979.1 - 1.2e-23 83.4 41.7 1.8e-06 28.4 0.1 11.2 10 3 2 12 12 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAX09979.1 - 3.7e-18 64.2 7.7 0.00017 21.3 0.1 10.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX09979.1 - 3.7e-17 61.6 41.0 0.039 14.8 0.1 11.5 10 2 2 12 12 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAX09979.1 - 1.2e-15 56.9 19.7 0.044 13.5 0.0 11.3 11 1 1 12 12 11 4 TPR repeat TPR_6 PF13174.6 GAX09979.1 - 2.2e-13 49.9 31.2 0.0074 16.9 0.1 12.6 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX09979.1 - 6.6e-11 41.7 37.9 0.0077 16.1 0.2 11.2 13 0 0 13 13 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX09979.1 - 3e-09 37.0 31.7 8.7e-05 22.7 0.7 8.5 8 1 1 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAX09979.1 - 1.7e-08 34.3 19.5 0.011 16.0 0.1 10.7 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX09979.1 - 0.0014 17.9 0.8 0.0014 17.9 0.8 5.3 5 2 1 6 6 6 2 Tetratricopeptide repeat PknG_TPR PF16918.5 GAX09979.1 - 0.042 12.6 12.8 0.13 11.0 0.0 3.8 4 0 0 4 4 4 0 Protein kinase G tetratricopeptide repeat TPR_9 PF13371.6 GAX09979.1 - 0.094 12.9 17.6 5.7 7.2 0.1 7.1 7 2 2 9 9 9 0 Tetratricopeptide repeat ABC_tran_2 PF16949.5 GAX09979.1 - 0.16 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative ATP-binding cassette Vps39_1 PF10366.9 GAX09979.1 - 5.5 7.3 12.7 5.5 7.3 0.1 4.6 6 0 0 6 6 4 0 Vacuolar sorting protein 39 domain 1 DUF572 PF04502.13 GAX09979.1 - 9.2 5.8 28.5 30 4.1 28.5 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF572) CS PF04969.16 GAX09981.1 - 5.3e-09 37.0 0.5 7.5e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 CS domain Sporozoite_P67 PF05642.11 GAX09981.1 - 0.15 10.2 4.2 0.18 9.8 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Forkhead_N PF08430.12 GAX09981.1 - 2.5 8.7 12.3 4.1 8.0 12.3 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region TIM21 PF08294.11 GAX09982.1 - 8.8e-13 48.4 0.1 1.2e-12 47.9 0.1 1.1 1 0 0 1 1 1 1 TIM21 STAS PF01740.21 GAX09983.1 - 2.8e-10 39.8 0.0 5.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 GAX09983.1 - 0.0012 18.9 0.0 0.094 12.8 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS_2 PF13466.6 GAX09983.1 - 0.0014 18.9 0.0 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 GAX09983.1 - 0.0021 16.9 3.0 0.0021 16.9 3.0 2.6 2 1 0 2 2 2 1 Sulfate permease family DUF3180 PF11377.8 GAX09983.1 - 0.18 11.9 9.0 0.14 12.3 0.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3180) Sm_like PF16243.5 GAX09984.1 - 0.015 15.4 0.2 0.16 12.1 0.1 2.4 2 0 0 2 2 2 0 Sm_like domain RRM_3 PF08777.11 GAX09984.1 - 0.048 13.7 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RabGAP-TBC PF00566.18 GAX09985.1 - 9e-30 103.9 0.8 7e-29 101.0 1.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CAP_N PF01213.19 GAX09985.1 - 1 8.7 15.3 0.23 10.9 3.9 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GAX09985.1 - 2.7 8.1 17.9 0.41 10.7 3.6 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 NDK PF00334.19 GAX09986.1 - 2.7e-54 182.8 0.0 3.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CPSF_A PF03178.15 GAX09989.1 - 1.9e-53 181.9 0.0 4.5e-53 180.6 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region adh_short PF00106.25 GAX09990.1 - 3.2e-26 92.0 0.1 2.3e-22 79.4 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX09990.1 - 1.4e-11 44.4 0.1 5.1e-11 42.6 0.1 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX09990.1 - 6.9e-07 29.3 0.1 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 KR domain TAT_signal PF10518.9 GAX09990.1 - 0.047 13.6 0.8 0.12 12.3 0.8 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence PsbQ PF05757.11 GAX09990.1 - 0.13 11.9 1.3 0.31 10.8 1.3 1.6 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) zf-HC5HC2H_2 PF13832.6 GAX09991.1 - 0.073 13.2 5.4 3.2 8.0 0.1 3.9 4 0 0 4 4 4 0 PHD-zinc-finger like domain TB PF00683.17 GAX09991.1 - 9.2 6.1 11.7 6 6.7 0.0 4.1 4 0 0 4 4 4 0 TB domain adh_short PF00106.25 GAX09992.1 - 1.7e-24 86.3 0.6 4.2e-16 59.0 1.8 3.3 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX09992.1 - 1e-11 44.9 0.7 2.7e-07 30.4 0.8 3.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX09992.1 - 2.4e-06 27.6 3.3 1e-05 25.5 0.5 2.5 2 1 1 3 3 3 1 KR domain 2-Hacid_dh_C PF02826.19 GAX09992.1 - 0.011 15.1 0.0 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 GAX09992.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4259 PF14078.6 GAX09992.1 - 0.086 13.6 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) LEA_5 PF00477.17 GAX09992.1 - 0.12 12.9 0.4 0.64 10.5 0.2 2.1 2 0 0 2 2 2 0 Small hydrophilic plant seed protein 3HCDH_N PF02737.18 GAX09992.1 - 0.14 12.1 0.4 0.23 11.3 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 GAX09992.1 - 0.23 11.2 2.3 6 6.7 0.2 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase DSPc PF00782.20 GAX09993.1 - 7.8e-20 71.0 0.0 9.8e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DMA PF03474.14 GAX09993.1 - 0.0084 15.7 0.1 0.024 14.3 0.1 1.8 1 0 0 1 1 1 1 DMRTA motif Y_phosphatase PF00102.27 GAX09993.1 - 0.016 14.8 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UBA PF00627.31 GAX09993.1 - 0.058 13.3 1.4 0.07 13.1 0.1 1.8 2 0 0 2 2 2 0 UBA/TS-N domain DDR_swiveling PF18427.1 GAX09993.1 - 0.06 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain DDE_Tnp_Tn3 PF01526.17 GAX09993.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain TIM PF00121.18 GAX09994.1 - 1.5e-80 270.1 0.0 1.6e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Ofd1_CTDD PF10637.9 GAX09995.1 - 1.9e-67 227.3 0.0 1.6e-63 214.5 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 GAX09995.1 - 4.5e-22 78.5 0.0 1e-21 77.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAX09995.1 - 1.5e-14 54.7 0.0 3.8e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_2 PF00890.24 GAX09996.1 - 9.9e-123 410.3 5.2 1.3e-122 409.9 5.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAX09996.1 - 2.5e-44 150.4 0.4 3.7e-44 149.8 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 GAX09996.1 - 0.0001 21.7 0.7 0.011 15.0 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX09996.1 - 0.00011 21.5 0.5 0.03 13.6 0.1 2.7 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 GAX09996.1 - 0.00045 19.4 1.9 0.11 11.5 1.7 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAX09996.1 - 0.0039 16.5 0.3 0.0039 16.5 0.3 2.1 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 GAX09996.1 - 0.011 15.3 0.3 0.039 13.5 0.3 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX09996.1 - 0.27 9.9 2.1 0.89 8.2 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein EF-hand_7 PF13499.6 GAX09997.1 - 3.8e-16 59.3 3.1 1.5e-09 38.2 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX09997.1 - 7.7e-12 44.1 3.4 8.1e-07 28.5 0.0 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 GAX09997.1 - 2e-10 39.4 9.9 1.8e-07 30.2 0.1 4.6 4 2 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAX09997.1 - 1.2e-07 31.5 3.2 0.00044 20.0 0.5 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX09997.1 - 4.5e-07 29.1 0.0 4.5e-07 29.1 0.0 3.2 6 0 0 6 6 6 1 EF hand EF-hand_9 PF14658.6 GAX09997.1 - 0.00057 20.2 0.0 0.3 11.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain PI-TkoII_IV PF18714.1 GAX09997.1 - 0.015 14.8 0.2 0.026 14.0 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV EFhand_Ca_insen PF08726.10 GAX09997.1 - 0.023 14.8 0.6 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.13 GAX09997.1 - 0.068 13.2 0.0 8.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Yop-YscD_cpl PF16697.5 GAX09998.1 - 0.0016 18.7 0.1 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 GAX09998.1 - 0.0027 18.0 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain HSF_DNA-bind PF00447.17 GAX09999.1 - 5.5e-29 100.6 1.5 1.3e-28 99.5 1.5 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Bap31_Bap29_C PF18035.1 GAX09999.1 - 0.084 12.9 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Matrilin_ccoil PF10393.9 GAX09999.1 - 0.14 12.0 0.5 0.31 10.9 0.5 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin 4HB_MCP_1 PF12729.7 GAX09999.1 - 0.22 11.0 2.2 0.36 10.3 1.0 1.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction MutS_V PF00488.21 GAX10000.1 - 0.0034 17.4 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain V AAA_23 PF13476.6 GAX10000.1 - 0.092 13.2 0.3 0.53 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAX10000.1 - 0.12 12.9 0.2 7.1 7.2 0.1 2.9 3 0 0 3 3 3 0 ABC transporter PsbW PF07123.12 GAX10001.1 - 0.098 12.7 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) PDZ_6 PF17820.1 GAX10002.1 - 3.6e-05 23.5 0.1 9e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX10002.1 - 0.00021 21.6 0.3 0.00048 20.4 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PT PF04886.12 GAX10002.1 - 0.0023 17.4 12.2 0.0023 17.4 12.2 6.1 2 2 2 4 4 4 1 PT repeat FixS PF03597.15 GAX10002.1 - 0.049 13.3 0.0 0.049 13.3 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type PDZ_2 PF13180.6 GAX10002.1 - 0.096 13.0 0.5 0.24 11.8 0.5 1.6 1 0 0 1 1 1 0 PDZ domain ATPgrasp_ST PF14397.6 GAX10003.1 - 0.00055 19.3 0.0 0.00085 18.7 0.0 1.2 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp STIMATE PF12400.8 GAX10004.1 - 1.1e-30 106.7 6.4 2.3e-30 105.7 6.4 1.5 1 0 0 1 1 1 1 STIMATE family DUF2621 PF11084.8 GAX10005.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Smr PF01713.21 GAX10006.1 - 1.5e-08 34.9 0.4 3e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 GAX10006.1 - 9.2e-06 25.5 2.4 9.2e-06 25.5 2.4 2.3 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 GAX10006.1 - 0.00081 20.1 3.9 0.0025 18.5 4.0 1.6 1 1 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 GAX10006.1 - 0.014 15.8 6.9 0.31 11.6 0.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GAX10006.1 - 0.022 14.7 2.3 0.022 14.7 2.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 GAX10006.1 - 0.041 14.1 3.3 2.8 8.2 0.6 2.4 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 GAX10006.1 - 4.5 7.2 13.3 0.39 10.6 4.0 2.7 2 1 0 2 2 2 0 CCCH-type zinc finger Seryl_tRNA_N PF02403.22 GAX10007.1 - 0.00019 21.6 5.0 0.00033 20.8 0.2 2.6 2 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DDE_Tnp_ISL3 PF01610.17 GAX10007.1 - 0.041 13.6 0.2 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 Transposase DUF2771 PF10969.8 GAX10007.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) DAGK_acc PF00609.19 GAX10008.1 - 8.5e-44 149.7 0.0 1.2e-42 146.0 0.0 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GAX10008.1 - 1.4e-21 76.4 0.0 3.1e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DEAD PF00270.29 GAX10009.1 - 1.9e-50 171.1 0.7 3.9e-50 170.0 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX10009.1 - 4.4e-30 104.3 0.0 3e-29 101.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX10009.1 - 0.00018 21.5 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX10009.1 - 0.07 13.4 3.6 0.16 12.2 1.4 2.7 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 GAX10009.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain SNF2_N PF00176.23 GAX10009.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain TMEM154 PF15102.6 GAX10010.1 - 0.041 13.8 0.5 0.067 13.1 0.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.16 GAX10010.1 - 0.048 12.4 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Biotin_lipoyl PF00364.22 GAX10011.1 - 4.1e-17 61.8 0.0 6.6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAX10011.1 - 0.0021 17.8 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like QRPTase_N PF02749.16 GAX10011.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain WW PF00397.26 GAX10012.1 - 9.8e-10 38.4 4.6 2.3e-09 37.2 4.6 1.7 1 0 0 1 1 1 1 WW domain tRNA_Me_trans PF03054.16 GAX10013.1 - 4.2e-72 242.9 0.0 7.7e-72 242.0 0.0 1.3 1 1 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 GAX10013.1 - 0.0021 17.2 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 GAX10013.1 - 0.0027 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 GAX10013.1 - 0.035 13.9 0.2 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 PP-loop family ThiI PF02568.14 GAX10013.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Mito_carr PF00153.27 GAX10014.1 - 7.3e-25 86.7 0.1 5.2e-11 42.3 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein RR_TM4-6 PF06459.12 GAX10015.1 - 0.013 15.4 5.2 0.018 14.9 5.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EF-hand_9 PF14658.6 GAX10015.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain YqzH PF14164.6 GAX10015.1 - 0.072 13.2 1.1 0.76 9.9 0.2 2.6 2 1 0 2 2 2 0 YqzH-like protein TMEM132D_C PF15706.5 GAX10015.1 - 0.084 12.7 0.7 0.35 10.7 0.0 2.2 2 1 0 2 2 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Nop14 PF04147.12 GAX10015.1 - 0.13 10.4 13.3 0.17 10.1 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family PRIMA1 PF16101.5 GAX10015.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Rax2 PF12768.7 GAX10015.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DDHD PF02862.17 GAX10015.1 - 0.19 11.9 2.2 0.33 11.1 2.2 1.3 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.6 GAX10015.1 - 0.19 10.1 0.1 0.27 9.6 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SDA1 PF05285.12 GAX10015.1 - 0.31 10.4 13.9 0.49 9.8 13.9 1.2 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 GAX10015.1 - 0.39 10.9 6.0 0.68 10.1 6.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 GAX10015.1 - 0.43 11.1 8.7 0.94 10.0 8.7 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Merozoite_SPAM PF07133.11 GAX10015.1 - 0.56 10.2 26.1 0.88 9.5 26.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 GAX10015.1 - 0.75 8.5 6.0 0.95 8.2 6.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GAX10015.1 - 0.97 8.1 7.1 1.6 7.4 7.1 1.3 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 GAX10015.1 - 1 9.1 11.6 1.7 8.4 11.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TMEM51 PF15345.6 GAX10015.1 - 1.7 8.4 7.2 1.2e+02 2.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 TFB6 PF17110.5 GAX10015.1 - 1.7 8.4 8.6 3.2 7.5 8.6 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 GAX10015.1 - 2.3 7.5 13.2 3.6 6.8 13.2 1.3 1 0 0 1 1 1 0 NOA36 protein V_ATPase_I PF01496.19 GAX10015.1 - 2.6 5.8 7.1 60 1.4 10.4 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 GAX10015.1 - 2.9 8.3 9.1 5.2 7.5 9.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 GAX10015.1 - 3.5 7.3 4.1 6 6.5 4.1 1.3 1 0 0 1 1 1 0 Connexin Sporozoite_P67 PF05642.11 GAX10015.1 - 5 5.1 9.7 7.2 4.6 9.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SPW PF03779.14 GAX10016.1 - 1.6 8.4 8.9 0.049 13.2 2.0 1.9 2 0 0 2 2 2 0 SPW repeat LapA_dom PF06305.11 GAX10016.1 - 1.9 8.3 5.1 1.3 8.9 0.6 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain IF-2B PF01008.17 GAX10017.1 - 1.4e-59 201.7 0.0 1.7e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RNA_pol_Rpc4 PF05132.14 GAX10017.1 - 0.0037 17.7 3.9 0.026 14.9 3.8 2.0 2 0 0 2 2 2 1 RNA polymerase III RPC4 PAH PF02671.21 GAX10018.1 - 1.1e-36 124.7 10.6 1.5e-17 63.5 4.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAX10018.1 - 2.5e-33 114.1 0.1 6.8e-33 112.6 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 GAX10018.1 - 6.4e-20 72.0 0.8 5.1e-19 69.1 0.0 2.7 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein SET PF00856.28 GAX10019.1 - 5.5e-09 36.6 0.0 9.8e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 SET domain Med2 PF11214.8 GAX10019.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 ATG16 PF08614.11 GAX10020.1 - 9.7e-05 22.7 122.7 0.026 14.7 18.7 6.8 3 2 3 6 6 6 4 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 GAX10020.1 - 0.24 11.2 67.5 0.1 12.4 7.8 6.8 4 2 3 7 7 7 0 Phage minor structural protein GP20 Ground-like PF04155.18 GAX10020.1 - 4.9 7.9 5.8 7.6 7.3 0.1 3.7 3 0 0 3 3 3 0 Ground-like domain GAS PF13851.6 GAX10020.1 - 8.6 5.7 103.0 0.086 12.2 2.2 8.0 3 2 2 7 7 7 0 Growth-arrest specific micro-tubule binding TPR_19 PF14559.6 GAX10021.1 - 6.3e-31 106.7 20.4 0.0018 18.7 0.0 11.2 9 2 2 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 GAX10021.1 - 2.8e-26 90.0 34.9 0.019 15.7 0.1 14.5 6 6 11 17 17 17 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10021.1 - 7.4e-25 85.0 26.3 0.045 13.9 0.0 14.1 16 0 0 16 16 14 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10021.1 - 4.1e-22 78.5 18.2 0.013 16.1 0.2 10.0 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 GAX10021.1 - 5.3e-19 67.2 21.2 0.031 14.6 0.1 13.8 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX10021.1 - 2e-17 63.3 32.2 0.012 15.9 0.6 11.5 10 3 2 12 12 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10021.1 - 2.5e-15 55.3 9.3 0.26 11.6 0.0 11.3 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10021.1 - 3.1e-14 52.1 2.3 0.59 10.0 0.0 10.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAX10021.1 - 5e-11 42.3 17.1 0.00047 19.5 2.0 6.1 3 2 2 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 GAX10021.1 - 5.6e-11 43.0 0.0 0.00072 19.6 0.0 5.4 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 GAX10021.1 - 1.6e-08 34.6 2.3 22 5.0 0.0 8.4 8 1 1 9 9 9 0 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 GAX10021.1 - 2e-06 28.1 16.8 18 6.2 0.0 10.6 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10021.1 - 5.9e-06 25.9 13.0 5.3 6.8 0.0 8.1 7 2 2 9 9 9 2 TPR repeat TPR_7 PF13176.6 GAX10021.1 - 1.3e-05 24.9 15.7 0.75 10.0 0.1 9.6 11 2 1 13 13 11 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10021.1 - 2.9e-05 24.1 20.9 0.36 11.0 0.4 7.9 7 2 1 8 8 8 1 Tetratricopeptide repeat Coatomer_E PF04733.14 GAX10021.1 - 0.00025 20.6 2.0 0.035 13.5 0.0 4.7 4 1 0 5 5 5 1 Coatomer epsilon subunit PerC PF06069.11 GAX10021.1 - 0.00074 19.7 1.0 0.016 15.5 0.0 3.2 3 0 0 3 3 3 1 PerC transcriptional activator TPR_10 PF13374.6 GAX10021.1 - 0.0083 16.0 22.0 12 5.9 0.0 9.1 10 0 0 10 10 10 0 Tetratricopeptide repeat NARP1 PF12569.8 GAX10021.1 - 0.0092 14.9 0.5 1.4 7.8 0.0 3.5 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 PRTase_3 PF15610.6 GAX10021.1 - 0.03 13.6 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 PRTase ComF-like TPR_3 PF07720.12 GAX10021.1 - 0.07 13.1 2.1 36 4.5 0.5 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX10021.1 - 0.2 11.8 2.8 38 4.5 0.0 5.2 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 GAX10021.1 - 0.27 11.5 17.1 8.3 6.7 0.0 6.1 7 1 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 GAX10021.1 - 2.5 9.0 11.0 68 4.5 0.0 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat LRR_8 PF13855.6 GAX10022.1 - 6.8e-28 96.2 34.2 4.1e-07 29.7 2.9 7.6 6 2 1 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GAX10022.1 - 5.1e-16 58.5 41.4 0.00035 20.9 0.4 9.8 5 3 3 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX10022.1 - 3.5e-06 26.8 31.9 6.9 7.7 0.2 12.6 11 3 1 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX10022.1 - 0.0001 22.1 15.2 6.9 7.0 0.1 8.6 8 0 0 8 8 8 1 Leucine Rich repeat Suppressor_P21 PF11479.8 GAX10022.1 - 0.0047 17.1 1.5 0.081 13.1 0.3 2.7 2 0 0 2 2 2 1 RNA silencing suppressor P21 C-terminal domain Peptidase_M3 PF01432.20 GAX10024.1 - 1.3e-137 459.8 0.0 1.9e-137 459.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 GAX10024.1 - 0.0071 16.0 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase M50B-like HSBP1 PF06825.12 GAX10024.1 - 0.021 14.7 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Patched PF02460.18 GAX10027.1 - 1.9e-09 36.2 40.0 1.1e-07 30.4 9.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 GAX10027.1 - 1.4e-08 34.7 10.6 1.4e-08 34.7 10.6 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 GAX10027.1 - 0.24 10.3 38.2 0.092 11.7 9.3 2.6 2 0 0 2 2 2 0 MMPL family Patched PF02460.18 GAX10028.1 - 1.7e-13 49.7 33.0 4.2e-13 48.3 4.4 2.6 2 1 1 3 3 3 3 Patched family MMPL PF03176.15 GAX10028.1 - 3.1e-10 39.5 14.0 1.3e-06 27.6 0.8 2.2 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 GAX10028.1 - 2.8e-07 30.5 8.6 2.8e-07 30.5 8.6 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation QueF PF14489.6 GAX10028.1 - 0.096 12.9 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein Phage_Gp23 PF10669.9 GAX10028.1 - 0.1 12.9 0.0 0.43 10.9 0.0 2.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CDT1_C PF16679.5 GAX10030.1 - 0.0099 16.3 6.3 0.032 14.7 1.4 2.5 2 0 0 2 2 2 2 DNA replication factor Cdt1 C-terminal domain Cas9_C PF18525.1 GAX10030.1 - 0.021 15.0 0.1 0.067 13.4 0.1 1.8 1 0 0 1 1 1 0 Cas9 C-terminal domain Mito_carr PF00153.27 GAX10031.1 - 1.1e-39 134.3 0.9 4.5e-16 58.5 0.5 3.9 1 1 2 3 3 3 3 Mitochondrial carrier protein Vma12 PF11712.8 GAX10031.1 - 0.046 13.8 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 2OG-FeII_Oxy_3 PF13640.6 GAX10032.1 - 2.7e-12 47.4 0.0 0.00013 22.8 0.0 2.9 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAX10032.1 - 7.5e-08 32.9 0.3 0.00069 20.2 0.0 3.1 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily GAS PF13851.6 GAX10033.1 - 5.1e-05 22.7 9.2 5.1e-05 22.7 9.2 9.1 2 2 6 8 8 8 4 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 GAX10033.1 - 0.0057 17.1 20.9 0.0057 17.1 20.9 7.4 2 2 3 5 5 5 2 Fez1 TolA_bind_tri PF16331.5 GAX10033.1 - 0.011 15.7 10.6 0.011 15.7 10.6 13.0 8 6 4 13 13 13 0 TolA binding protein trimerisation Spc7 PF08317.11 GAX10033.1 - 0.034 13.0 154.7 0.017 14.0 23.3 7.3 2 2 5 7 7 7 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 GAX10033.1 - 0.052 13.6 172.1 0.037 14.0 5.8 8.4 3 2 3 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5631 PF18645.1 GAX10033.1 - 2.5 8.6 17.7 4.7 7.7 0.0 6.3 7 0 0 7 7 7 0 Family of unknown function (DUF5631) CALCOCO1 PF07888.11 GAX10033.1 - 9 5.0 153.7 0.0059 15.5 27.7 5.5 2 2 4 6 6 6 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3800 PF12686.7 GAX10033.1 - 9.1 6.9 17.8 1.8e+04 -9.3 17.8 5.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) SLD5_C PF16922.5 GAX10034.1 - 0.0092 16.2 0.1 0.049 13.8 0.1 2.2 1 1 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus CttA_N PF18244.1 GAX10034.1 - 0.11 12.9 0.1 0.27 11.7 0.1 1.7 1 0 0 1 1 1 0 Cellulose-binding protein CttA N-terminal domain TPR_16 PF13432.6 GAX10035.1 - 6e-11 42.8 15.3 4.3e-06 27.3 0.5 4.5 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10035.1 - 1e-09 37.7 14.7 0.0005 20.0 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX10035.1 - 1.3e-09 38.0 11.1 0.00052 20.6 0.1 5.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX10035.1 - 9.3e-09 35.7 11.3 0.0032 17.9 3.0 4.8 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAX10035.1 - 4e-07 30.2 4.5 0.025 15.2 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10035.1 - 5.8e-07 29.2 5.5 1.3 9.5 0.0 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10035.1 - 1.7e-06 27.6 3.2 0.019 14.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX10035.1 - 4.6e-05 23.5 0.2 14 6.3 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10035.1 - 0.00016 21.3 1.6 0.99 9.1 0.0 3.8 4 1 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 GAX10035.1 - 0.00066 19.9 11.4 0.094 13.0 1.8 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAX10035.1 - 0.0027 17.0 3.4 0.0048 16.2 3.4 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX10035.1 - 0.0051 16.7 3.2 3.3 7.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10035.1 - 0.28 11.4 0.0 0.28 11.4 0.0 3.6 3 2 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX10035.1 - 1.8 9.4 7.4 4.1 8.3 0.3 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 GAX10036.1 - 3.8e-06 26.8 0.0 6.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX10036.1 - 0.00011 22.8 0.0 0.00024 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10036.1 - 0.0043 17.7 0.0 0.013 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10036.1 - 0.033 14.9 0.0 0.06 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ank_5 PF13857.6 GAX10037.1 - 1.1e-13 51.0 0.7 6.5e-09 35.9 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX10037.1 - 1.7e-06 28.5 0.8 0.0094 16.5 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX10037.1 - 0.019 15.5 0.5 5.7 7.6 0.0 3.4 2 2 2 4 4 4 0 Ankyrin repeats (many copies) Myosin_head PF00063.21 GAX10038.1 - 2e-159 532.0 0.6 2e-159 532.0 0.6 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_16 PF13191.6 GAX10038.1 - 0.023 15.1 0.0 0.023 15.1 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 GAX10038.1 - 0.023 14.0 0.1 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DUF4407 PF14362.6 GAX10038.1 - 0.039 13.3 10.0 0.091 12.1 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_22 PF13401.6 GAX10038.1 - 0.048 13.9 0.2 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAX10038.1 - 0.06 13.7 0.0 0.29 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX10038.1 - 0.11 13.0 3.9 5.7 7.4 0.0 3.2 2 1 0 2 2 2 0 ABC transporter DUF87 PF01935.17 GAX10038.1 - 0.19 11.8 9.1 5.4 7.1 6.3 2.9 2 0 0 2 2 2 0 Helicase HerA, central domain IQ PF00612.27 GAX10038.1 - 2.2 8.3 33.9 3.8 7.6 1.1 6.8 5 1 1 6 6 6 0 IQ calmodulin-binding motif Not1 PF04054.15 GAX10039.1 - 4.4e-128 427.3 0.3 1.3e-126 422.5 0.4 2.4 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAX10039.1 - 3.4e-82 275.2 0.2 9.4e-82 273.7 0.0 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 GAX10039.1 - 2.8e-68 228.9 0.1 1.1e-67 226.9 0.1 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 GAX10039.1 - 1.8e-63 212.8 2.0 1.8e-63 212.8 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 GAX10039.1 - 3.6e-08 33.6 0.0 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat PrmA PF06325.13 GAX10040.1 - 4.2e-34 118.3 0.0 6.2e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAX10040.1 - 2.9e-10 40.2 0.0 3.8e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10040.1 - 6.4e-08 33.2 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX10040.1 - 3.6e-07 29.9 0.0 5.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltrans_SAM PF10672.9 GAX10040.1 - 9.2e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_11 PF08241.12 GAX10040.1 - 0.00028 21.5 0.0 0.00047 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX10040.1 - 0.00041 20.2 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 GAX10040.1 - 0.00074 19.4 0.0 0.0027 17.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX10040.1 - 0.00077 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 GAX10040.1 - 0.00078 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10040.1 - 0.003 18.2 0.0 0.0053 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX10040.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.20 GAX10040.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.18 GAX10040.1 - 0.047 13.4 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Methyltransf_32 PF13679.6 GAX10040.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 GAX10040.1 - 0.17 11.4 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_9 PF08003.11 GAX10040.1 - 0.21 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AAA_16 PF13191.6 GAX10041.1 - 9.7e-14 52.1 0.0 2.7e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 GAX10041.1 - 0.00049 19.1 0.0 0.00091 18.2 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.6 GAX10041.1 - 0.0094 16.5 0.0 0.023 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX10041.1 - 0.012 16.1 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TPR_MalT PF17874.1 GAX10041.1 - 0.018 14.4 0.9 8.1 5.7 0.0 3.0 3 0 0 3 3 3 0 MalT-like TPR region Zeta_toxin PF06414.12 GAX10041.1 - 0.049 12.9 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TPR_12 PF13424.6 GAX10041.1 - 0.052 13.9 5.5 0.52 10.6 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat dNK PF01712.19 GAX10041.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_22 PF13401.6 GAX10041.1 - 0.062 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAX10041.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain HSP33 PF01430.19 GAX10042.1 - 2e-61 207.8 0.0 2.4e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Hsp33 protein HTH_Tnp_Tc3_2 PF01498.18 GAX10042.1 - 0.31 11.3 0.7 9.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Transposase Ribosomal_L21p PF00829.21 GAX10044.1 - 6.3e-27 93.8 1.2 8.1e-27 93.4 1.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF1462 PF07315.11 GAX10045.1 - 0.071 13.4 0.0 0.091 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) PUF PF00806.19 GAX10047.1 - 1.2e-44 147.5 1.1 3e-07 29.8 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat FliG_C PF01706.16 GAX10047.1 - 0.0024 18.1 0.4 0.012 15.7 0.1 2.2 2 0 0 2 2 2 1 FliG C-terminal domain EPL1 PF10513.9 GAX10048.1 - 2.9e-09 37.5 0.6 6.8e-09 36.3 0.6 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like Ion_trans_2 PF07885.16 GAX10049.1 - 0.0001 22.2 6.7 0.00019 21.3 6.7 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 GAX10049.1 - 0.0076 15.5 3.8 0.011 15.0 3.8 1.2 1 0 0 1 1 1 1 Ion transport protein IRK_C PF17655.1 GAX10049.1 - 0.03 13.9 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 GAX10050.1 - 0.0046 16.9 8.9 0.0071 16.3 7.7 1.9 1 1 1 2 2 2 1 Ion channel IRK_C PF17655.1 GAX10050.1 - 0.23 11.0 0.2 8.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 GAX10050.1 - 1.4 8.8 4.5 2.3 8.0 4.5 1.4 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain SCAMP PF04144.13 GAX10050.1 - 1.6 9.0 9.8 2.7 8.3 9.8 1.3 1 0 0 1 1 1 0 SCAMP family Wzy_C PF04932.15 GAX10051.1 - 0.048 13.3 0.0 0.3 10.7 0.0 2.2 2 1 0 2 2 2 0 O-Antigen ligase Pro_isomerase PF00160.21 GAX10054.1 - 1.9e-48 164.7 0.1 2e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ARD PF03079.14 GAX10055.1 - 1.9e-45 154.9 0.4 3.2e-44 150.9 0.4 2.1 1 1 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.19 GAX10055.1 - 1.1e-08 35.1 0.5 1.8e-08 34.4 0.5 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 GAX10055.1 - 5.6e-08 32.4 0.2 8.9e-08 31.7 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GAX10055.1 - 7.7e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Glyco_transf_11 PF01531.16 GAX10055.1 - 0.0016 17.7 0.1 0.0022 17.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 Cupin_3 PF05899.12 GAX10055.1 - 0.042 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) tRNA-synt_1c_C PF03950.18 GAX10056.1 - 0.046 13.6 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Kinesin PF00225.23 GAX10057.1 - 6.6e-49 166.6 4.1 1.4e-48 165.6 4.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX10057.1 - 6.6e-08 32.6 0.1 1.5e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 GAX10057.1 - 0.0011 19.4 0.8 0.0051 17.2 0.2 2.2 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 GAX10057.1 - 0.01 14.9 0.0 0.025 13.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 GAX10057.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MaoC_dehydratas PF01575.19 GAX10058.1 - 2.5e-14 52.9 0.0 5.9e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain PH PF00169.29 GAX10059.1 - 0.021 15.3 0.2 0.054 14.0 0.2 1.8 1 1 0 1 1 1 0 PH domain Rad50_zn_hook PF04423.14 GAX10059.1 - 0.11 12.3 0.7 0.21 11.4 0.7 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Umbravirus_LDM PF04817.12 GAX10059.1 - 1.2 8.4 5.1 0.46 9.8 0.2 2.1 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family Abhydrolase_3 PF07859.13 GAX10060.1 - 1.6e-34 119.6 0.0 3.5e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAX10060.1 - 0.00053 19.0 0.0 0.00083 18.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 GAX10060.1 - 0.0093 16.6 0.3 0.0093 16.6 0.3 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Mon1 PF03164.14 GAX10060.1 - 0.024 13.7 1.8 0.041 13.0 1.8 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 GATase_5 PF13507.6 GAX10061.1 - 1.2e-104 349.0 0.0 1.7e-104 348.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 GAX10061.1 - 1.1e-34 119.8 1.3 2.5e-19 70.0 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 GAX10061.1 - 2.1e-15 56.7 0.0 4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 GAX10061.1 - 4.6e-12 46.3 0.0 9.9e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Cyclin_N PF00134.23 GAX10062.1 - 1.4e-18 66.9 0.4 2.1e-18 66.3 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX10062.1 - 1.7e-06 28.1 1.5 2.8e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Acatn PF13000.7 GAX10063.1 - 1.1e-92 311.4 3.3 1e-71 242.1 0.3 3.2 1 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 PPR PF01535.20 GAX10064.1 - 0.0092 16.2 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 1 PPR repeat Imm71 PF15602.6 GAX10064.1 - 0.033 14.2 0.1 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 71 TPR_7 PF13176.6 GAX10064.1 - 0.089 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2358 PF10184.9 GAX10065.1 - 1.3e-11 44.7 0.0 2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) WAP PF00095.21 GAX10065.1 - 0.025 14.9 5.0 0.025 14.9 5.0 1.7 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Glyco_tranf_2_4 PF13704.6 GAX10066.1 - 0.00019 21.9 0.9 0.00071 20.1 0.9 2.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mod_r PF07200.13 GAX10067.1 - 0.0062 16.7 3.0 0.0062 16.7 3.0 2.8 2 1 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein TPR_12 PF13424.6 GAX10067.1 - 0.048 14.0 0.2 0.19 12.0 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat G6PD_bact PF10786.9 GAX10068.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Coprogen_oxidas PF01218.18 GAX10069.1 - 6.3e-132 438.8 0.5 7.6e-132 438.5 0.5 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase zf-C2H2_4 PF13894.6 GAX10070.1 - 7.1e-13 48.2 33.3 0.0063 17.3 0.4 7.0 6 0 0 6 6 6 5 C2H2-type zinc finger CpXC PF14353.6 GAX10070.1 - 3.5e-06 27.0 23.0 0.076 13.1 0.7 6.0 5 1 1 6 6 6 2 CpXC protein zf-C2H2 PF00096.26 GAX10070.1 - 4e-06 27.0 37.4 0.02 15.3 0.4 6.8 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 GAX10070.1 - 9.5e-06 25.3 17.1 0.0058 16.4 0.2 5.1 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 GAX10070.1 - 0.00046 20.4 16.0 0.008 16.4 0.9 4.7 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 GAX10070.1 - 0.00051 19.9 1.5 0.00051 19.9 1.5 5.3 6 0 0 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_9 PF14369.6 GAX10070.1 - 0.0013 19.0 18.9 4.8 7.5 0.0 7.0 7 0 0 7 7 7 2 zinc-ribbon PHD PF00628.29 GAX10070.1 - 0.0031 17.4 5.6 0.0031 17.4 5.6 3.7 4 0 0 4 4 3 1 PHD-finger C1_2 PF03107.16 GAX10070.1 - 0.0075 16.6 0.7 0.0075 16.6 0.7 4.9 5 0 0 5 5 5 1 C1 domain zf-HC5HC2H_2 PF13832.6 GAX10070.1 - 0.013 15.7 0.3 0.013 15.7 0.3 3.5 3 1 1 4 4 2 0 PHD-zinc-finger like domain Zn-C2H2_12 PF18112.1 GAX10070.1 - 0.04 14.4 2.8 13 6.4 0.0 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-ribbon_3 PF13248.6 GAX10070.1 - 0.044 13.2 0.2 0.044 13.2 0.2 5.5 7 0 0 7 7 5 0 zinc-ribbon domain UL17 PF17640.2 GAX10070.1 - 0.044 13.8 1.9 0.084 12.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized UL17 zf-C2H2_2 PF12756.7 GAX10070.1 - 0.068 13.5 18.3 0.47 10.8 0.5 5.4 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 GAX10070.1 - 0.098 13.3 3.8 0.23 12.1 0.3 3.3 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 GAX10070.1 - 0.63 10.5 6.2 4.2 7.9 0.0 4.3 4 0 0 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zf_RING PF16744.5 GAX10070.1 - 0.68 10.1 4.6 0.32 11.2 0.5 2.7 2 0 0 2 2 1 0 KIAA1045 RING finger zf-RING_7 PF02591.15 GAX10070.1 - 0.8 9.9 15.4 8 6.8 0.3 5.3 5 0 0 5 5 5 0 C4-type zinc ribbon domain XPA_N PF01286.18 GAX10070.1 - 0.84 9.7 9.4 1.4 9.1 0.1 4.8 5 0 0 5 5 5 0 XPA protein N-terminal Zn-ribbon_8 PF09723.10 GAX10070.1 - 1.5 9.0 28.7 12 6.1 0.1 7.1 6 1 1 7 7 7 0 Zinc ribbon domain PHD_4 PF16866.5 GAX10070.1 - 4.2 7.5 12.0 0.66 10.1 4.6 3.6 3 1 0 3 3 3 0 PHD-finger YhfH PF14149.6 GAX10070.1 - 4.8 7.2 11.5 3.6 7.7 0.1 4.6 5 0 0 5 5 4 0 YhfH-like protein zf-C2H2_aberr PF17017.5 GAX10070.1 - 5.2 7.2 27.1 1.1 9.4 0.2 5.6 6 0 0 6 6 6 0 Aberrant zinc-finger LCAT PF02450.15 GAX10071.1 - 2.7e-45 155.2 0.0 1.2e-26 93.8 0.0 2.4 2 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Fumble PF03630.14 GAX10074.1 - 1.4e-109 366.3 2.1 7.8e-108 360.5 2.1 2.7 1 1 0 1 1 1 1 Fumble Methyltransf_17 PF12692.7 GAX10074.1 - 0.039 13.9 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DUF1943 PF09172.11 GAX10074.1 - 0.059 12.6 0.4 0.1 11.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Nab6_mRNP_bdg PF10567.9 GAX10074.1 - 0.068 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA-recognition motif Mito_carr PF00153.27 GAX10075.1 - 2.1e-34 117.3 7.3 4.3e-19 68.2 0.4 4.7 4 2 0 4 4 4 3 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.10 GAX10075.1 - 0.38 10.8 0.1 0.38 10.8 0.1 2.7 4 0 0 4 4 4 0 Cytochrome B6-F complex Fe-S subunit Glyco_hydro_72 PF03198.14 GAX10076.1 - 6e-59 199.8 0.2 8.5e-59 199.3 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 GAX10076.1 - 0.016 14.7 0.0 0.099 12.1 0.0 2.0 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Plus-3 PF03126.18 GAX10078.1 - 1.3e-23 83.6 0.0 3.1e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain BSMAP PF12280.8 GAX10079.1 - 0.0019 18.5 1.3 0.053 13.7 0.0 2.1 2 0 0 2 2 2 1 Brain specific membrane anchored protein Tugs PF17840.1 GAX10079.1 - 0.27 11.4 1.1 1.1 9.5 0.1 2.1 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain Pox_Ag35 PF03286.14 GAX10079.1 - 0.34 10.7 7.1 0.63 9.8 7.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 GAX10079.1 - 1.6 6.8 11.8 2.5 6.2 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family PRP38_assoc PF12871.7 GAX10079.1 - 3.8 8.2 15.2 1.7 9.3 10.5 2.4 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TRAP_alpha PF03896.16 GAX10079.1 - 4 6.5 6.0 6.6 5.9 6.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PTPRCAP PF15713.5 GAX10079.1 - 4.9 7.4 14.8 0.39 11.0 10.0 1.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GAX10079.1 - 5.4 5.2 10.4 1.9 6.7 7.5 1.6 2 0 0 2 2 2 0 CDC45-like protein Astro_capsid_p PF12226.8 GAX10079.1 - 9.5 5.3 10.5 13 4.8 10.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF179 PF02622.15 GAX10080.1 - 7.7e-10 38.9 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 LAT PF15234.6 GAX10080.1 - 0.0037 17.0 0.4 0.0059 16.4 0.4 1.4 1 0 0 1 1 1 1 Linker for activation of T-cells GCIP PF13324.6 GAX10080.1 - 0.01 15.4 2.7 0.016 14.9 2.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 GAX10080.1 - 0.058 11.7 1.5 0.074 11.3 1.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 GAX10080.1 - 0.073 13.5 13.9 0.15 12.4 13.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.13 GAX10080.1 - 0.089 12.9 3.7 0.13 12.4 3.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Utp21 PF04192.12 GAX10080.1 - 0.11 11.9 0.8 0.25 10.8 0.5 1.6 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Myc_N PF01056.18 GAX10080.1 - 0.39 10.6 3.3 0.31 10.9 1.6 1.6 2 0 0 2 2 2 0 Myc amino-terminal region DUF2457 PF10446.9 GAX10080.1 - 0.53 9.4 18.0 0.75 8.9 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 GAX10080.1 - 0.68 9.9 3.9 1.2 9.2 3.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 GAX10080.1 - 1.7 6.8 9.7 2.3 6.3 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAX10080.1 - 3.5 5.6 15.2 4.8 5.2 15.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 GAX10080.1 - 5.1 6.8 7.6 8.6 6.0 7.6 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GAX10080.1 - 8.1 5.7 14.2 12 5.1 14.2 1.2 1 0 0 1 1 1 0 NOA36 protein TraB PF01963.17 GAX10082.1 - 6.4e-18 65.6 2.3 6.9e-10 39.3 1.7 2.3 2 1 0 2 2 2 2 TraB family Gp-FAR-1 PF05823.12 GAX10082.1 - 0.064 13.6 1.0 0.11 12.8 0.3 1.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SMAP PF15477.6 GAX10082.1 - 0.12 13.4 0.8 0.44 11.5 0.2 2.2 2 0 0 2 2 2 0 Small acidic protein family CbiA PF01656.23 GAX10082.1 - 0.16 12.0 0.2 0.4 10.7 0.1 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ank_2 PF12796.7 GAX10084.1 - 0.035 14.7 0.0 0.057 14.0 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3551 PF12071.8 GAX10085.1 - 0.069 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) DUF296 PF03479.15 GAX10086.1 - 1.9e-25 89.3 0.8 2.2e-25 89.1 0.8 1.0 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Hydrolase_4 PF12146.8 GAX10087.1 - 1e-11 44.6 0.0 3.3e-08 33.1 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX10087.1 - 1.1e-06 29.4 0.0 1.7e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX10087.1 - 5.4e-05 22.8 0.3 0.00098 18.7 0.3 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAX10087.1 - 6.2e-05 22.8 0.2 0.0005 19.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 GAX10087.1 - 0.0031 16.8 0.0 0.0081 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 GAX10087.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 GAX10087.1 - 0.0065 16.4 0.1 0.02 14.9 0.1 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Esterase PF00756.20 GAX10087.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Imm61 PF15598.6 GAX10087.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 61 Secretin_N_2 PF07655.13 GAX10090.1 - 0.28 11.8 2.7 0.89 10.1 0.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Glyco_transf_92 PF01697.27 GAX10094.1 - 6.1e-17 62.1 0.2 1.6e-16 60.7 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GAX10094.1 - 1.2e-07 32.1 0.0 3.4e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 bZIP_1 PF00170.21 GAX10095.1 - 0.013 15.6 13.0 0.032 14.3 11.9 2.1 1 1 1 2 2 2 0 bZIP transcription factor SAB PF04382.13 GAX10095.1 - 0.024 14.7 1.2 0.052 13.6 1.2 1.5 1 0 0 1 1 1 0 SAB domain bZIP_2 PF07716.15 GAX10095.1 - 2 8.5 17.6 1.5 9.0 15.2 1.9 1 1 1 2 2 2 0 Basic region leucine zipper Aldedh PF00171.22 GAX10096.1 - 2.2e-136 455.1 0.1 2.6e-136 454.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAX10096.1 - 0.014 14.9 0.0 0.089 12.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DnaJ PF00226.31 GAX10097.1 - 1.5e-23 82.6 1.9 2.9e-23 81.8 0.5 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 GAX10097.1 - 6.9e-16 57.0 11.1 0.0014 18.6 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10097.1 - 6e-13 48.0 9.2 1.6e-06 27.6 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX10097.1 - 2.5e-08 34.1 14.0 7.7e-05 22.9 0.9 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10097.1 - 5.2e-06 27.0 11.6 0.0018 18.9 0.0 5.4 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10097.1 - 0.00017 21.5 9.0 0.073 13.3 0.4 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX10097.1 - 0.00023 21.0 5.7 0.12 12.5 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10097.1 - 0.0013 18.8 4.6 0.31 11.2 0.6 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX10097.1 - 0.0043 17.2 3.5 0.019 15.2 0.8 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAX10097.1 - 0.0046 17.4 4.5 0.019 15.5 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX10097.1 - 0.0063 17.1 7.5 0.079 13.6 1.3 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 GAX10097.1 - 0.01 15.9 0.2 0.14 12.2 0.1 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 GAX10097.1 - 0.021 15.2 0.6 4.8 7.8 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10097.1 - 1 9.1 8.8 57 3.5 0.2 5.3 6 0 0 6 6 6 0 TPR repeat BTAD PF03704.17 GAX10097.1 - 4.3 7.8 10.7 0.096 13.1 1.4 3.0 2 0 0 2 2 2 0 Bacterial transcriptional activator domain SNO PF01174.19 GAX10098.1 - 7.9e-41 140.0 0.0 6.6e-32 110.9 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAX10098.1 - 5.7e-05 22.8 0.2 0.00012 21.8 0.2 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 GAX10098.1 - 0.0001 22.2 0.8 0.00086 19.1 0.8 2.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I UPF0180 PF03698.13 GAX10098.1 - 0.049 13.8 0.3 15 5.9 0.0 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0180) LCIB_C_CA PF18599.1 GAX10099.1 - 1.7e-72 243.3 0.0 2.5e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases HMG_box PF00505.19 GAX10100.1 - 2.1e-07 31.2 7.9 3.1e-05 24.3 0.6 2.7 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX10100.1 - 1.2e-06 29.0 5.0 7.4e-05 23.3 0.2 2.9 3 0 0 3 3 3 2 HMG-box domain Trypsin_2 PF13365.6 GAX10101.1 - 1.7e-31 110.1 3.1 1.7e-31 110.1 3.1 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 GAX10101.1 - 6e-12 45.7 0.0 2.2e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 GAX10101.1 - 2.2e-11 44.0 0.2 4e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 GAX10101.1 - 2.7e-07 30.3 0.1 6.7e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX10101.1 - 0.00012 22.4 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 GAX10101.1 - 0.028 13.1 0.0 0.75 8.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 PNP_UDP_1 PF01048.20 GAX10101.1 - 0.1 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily LSM PF01423.22 GAX10101.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 LSM domain eIF-5a PF01287.20 GAX10102.1 - 7.5e-09 35.6 0.2 1.4e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold FHIPEP PF00771.20 GAX10102.1 - 0.033 12.7 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family Carb_anhydrase PF00194.21 GAX10104.1 - 6.1e-14 52.2 0.1 1.5e-09 37.8 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase UCH PF00443.29 GAX10105.1 - 9.8e-39 133.4 0.1 2.2e-38 132.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX10105.1 - 5.3e-17 62.4 3.0 2e-14 53.9 3.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UAA PF08449.11 GAX10106.1 - 5.7e-52 176.8 20.1 6.8e-52 176.6 20.1 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX10106.1 - 4.7e-08 33.3 25.9 9.6e-05 22.6 9.2 2.9 2 1 1 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 GAX10106.1 - 2.8e-07 29.8 5.3 2.8e-07 29.8 5.3 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 GAX10106.1 - 2e-05 24.1 15.7 3.1e-05 23.5 15.7 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family Pex24p PF06398.11 GAX10106.1 - 0.049 12.6 0.9 0.075 12.0 0.9 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Halogen_Hydrol PF10112.9 GAX10106.1 - 0.12 12.4 0.3 0.29 11.1 0.3 1.7 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TMEM234 PF10639.9 GAX10106.1 - 2.1 8.4 11.4 0.051 13.6 0.9 2.6 2 1 0 2 2 2 0 Putative transmembrane family 234 ACT_6 PF13740.6 GAX10107.1 - 1.2e-13 50.8 0.0 2.7e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 ACT domain Mpv17_PMP22 PF04117.12 GAX10107.1 - 3e-11 43.4 0.4 6.5e-11 42.3 0.4 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family ACT_4 PF13291.6 GAX10107.1 - 1.7e-09 38.2 0.4 0.0011 19.6 0.0 2.9 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 GAX10107.1 - 8.7e-06 25.4 0.0 0.00014 21.6 0.0 2.5 2 0 0 2 2 2 1 ACT domain WHEP-TRS PF00458.20 GAX10107.1 - 0.019 15.1 0.8 7.8 6.7 0.1 2.5 2 0 0 2 2 2 0 WHEP-TRS domain ACT_7 PF13840.6 GAX10107.1 - 0.029 14.2 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 ACT domain NUC173 PF08161.12 GAX10108.1 - 4.3e-26 91.8 0.0 7.3e-23 81.3 0.0 3.1 2 0 0 2 2 2 2 NUC173 domain Cnd1 PF12717.7 GAX10108.1 - 4.3e-05 23.6 3.4 0.19 11.7 0.0 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX10108.1 - 0.00058 19.9 1.3 2.8 8.5 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat DUF3314 PF11771.8 GAX10108.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) DUF4042 PF13251.6 GAX10108.1 - 0.32 10.7 10.2 0.073 12.8 0.9 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) Thioredoxin PF00085.20 GAX10111.1 - 3.9e-19 68.6 0.3 9.4e-19 67.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX10111.1 - 4.3e-07 30.4 0.6 9.9e-07 29.2 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX10111.1 - 0.0004 20.5 0.5 0.0009 19.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 GAX10111.1 - 0.0024 17.8 0.3 0.0093 15.9 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 GAX10111.1 - 0.0054 17.0 1.0 0.074 13.4 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 GAX10111.1 - 0.0066 16.2 0.2 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 Redoxin FapA PF03961.13 GAX10111.1 - 0.043 12.4 1.8 0.056 12.0 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5098 PF17023.5 GAX10111.1 - 0.051 12.5 3.6 0.07 12.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) OST3_OST6 PF04756.13 GAX10111.1 - 0.06 12.7 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF2935 PF11155.8 GAX10111.1 - 0.095 13.0 1.4 0.52 10.6 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Thioredoxin PF00085.20 GAX10112.1 - 0.00022 21.2 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin DUF1479 PF07350.12 GAX10112.1 - 0.055 12.2 0.2 0.065 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) UCH PF00443.29 GAX10113.1 - 4.8e-46 157.3 0.0 7.2e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX10113.1 - 4e-17 62.8 0.0 7.9e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4175 PF13779.6 GAX10113.1 - 0.19 9.6 0.1 0.26 9.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sulfotransfer_3 PF13469.6 GAX10114.1 - 2.7e-37 129.3 0.0 7.9e-37 127.7 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 GAX10114.1 - 1.1e-13 51.3 0.1 4.5e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase domain TPR_1 PF00515.28 GAX10114.1 - 0.00019 21.1 0.0 0.12 12.3 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10114.1 - 0.00076 19.4 0.1 1.6 9.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10114.1 - 0.013 16.2 0.2 0.044 14.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10114.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX10114.1 - 0.42 10.9 2.6 44 4.5 0.0 3.2 3 1 0 4 4 4 0 Tetratricopeptide repeat Rhomboid PF01694.22 GAX10116.1 - 8.1e-30 103.8 18.8 8.1e-30 103.8 18.8 1.9 2 0 0 2 2 2 1 Rhomboid family Zn-ribbon_8 PF09723.10 GAX10116.1 - 0.048 13.8 0.1 8.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain FSH1 PF03959.13 GAX10117.1 - 4.5e-13 49.4 0.0 1.2e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) FAM176 PF14851.6 GAX10117.1 - 0.03 14.0 0.9 0.061 13.0 0.9 1.5 1 0 0 1 1 1 0 FAM176 family GTP_EFTU PF00009.27 GAX10118.1 - 4e-29 101.5 0.1 9.4e-29 100.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAX10118.1 - 4.6e-07 29.9 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAX10118.1 - 2.7e-05 23.7 0.4 0.00032 20.2 0.4 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RIBIOP_C PF04950.12 GAX10118.1 - 0.0012 18.3 0.3 0.0025 17.3 0.3 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal GTP_EFTU_D2 PF03144.25 GAX10118.1 - 0.0033 17.8 3.2 0.0048 17.3 0.1 3.0 4 0 0 4 4 4 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 GAX10118.1 - 0.012 15.4 0.3 7.1 6.3 0.1 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 GAX10118.1 - 0.021 14.6 0.1 0.47 10.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX10118.1 - 0.03 14.2 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 GAX10118.1 - 0.039 13.3 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.19 GAX10118.1 - 0.22 11.1 1.2 1.9 8.1 0.1 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arc_PepC_II PF06847.11 GAX10119.1 - 0.2 12.2 1.5 0.18 12.3 0.4 1.5 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Conotoxin PF02950.17 GAX10119.1 - 0.33 12.0 1.2 1.2 10.2 1.2 1.9 1 1 0 1 1 1 0 Conotoxin TPT PF03151.16 GAX10120.1 - 4.3e-93 311.9 6.5 5.1e-93 311.6 6.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX10120.1 - 2.8e-16 59.9 14.5 4.5e-08 33.4 2.3 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAX10120.1 - 0.0093 15.2 6.7 0.047 12.9 6.7 1.9 1 1 0 1 1 1 1 UAA transporter family FA_hydroxylase PF04116.13 GAX10121.1 - 7e-17 62.0 8.3 7e-17 62.0 8.3 2.7 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily RETICULATA-like PF11891.8 GAX10122.1 - 2.5e-43 148.0 1.1 3.1e-43 147.6 1.1 1.1 1 0 0 1 1 1 1 Protein RETICULATA-related MatE PF01554.18 GAX10123.1 - 2.2e-15 56.7 26.3 5.7e-14 52.1 7.2 3.0 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAX10123.1 - 5.7e-06 26.5 10.6 5.7e-06 26.5 10.6 2.7 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain GST_N PF02798.20 GAX10124.1 - 8.5e-12 45.2 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAX10124.1 - 6.4e-11 42.5 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX10124.1 - 1.6e-07 31.5 0.1 2.7e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX10124.1 - 0.00012 22.0 0.0 0.00035 20.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX10124.1 - 0.00037 20.7 0.2 0.002 18.3 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAX10124.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin zf-MIZ PF02891.20 GAX10125.1 - 4.3e-15 55.2 1.5 8.2e-15 54.3 1.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 GAX10125.1 - 4.1e-05 23.3 0.1 9.6e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Aldo_ket_red PF00248.21 GAX10126.1 - 8.5e-25 87.5 0.0 8.9e-24 84.2 0.0 1.9 1 1 1 2 2 2 1 Aldo/keto reductase family DUF1343 PF07075.11 GAX10126.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) DHHC PF01529.20 GAX10126.1 - 0.094 12.8 0.3 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase ANAPC4_WD40 PF12894.7 GAX10127.1 - 4.6e-31 107.0 0.1 0.00012 22.3 0.0 12.1 3 2 10 13 13 13 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX10127.1 - 4.1e-19 68.6 19.7 0.0092 16.8 0.2 11.2 12 0 0 12 12 12 4 WD domain, G-beta repeat WD40_like PF17005.5 GAX10127.1 - 9.8e-12 44.8 0.0 0.024 14.0 0.0 5.0 4 2 0 4 4 4 3 WD40-like domain eIF2A PF08662.11 GAX10127.1 - 5.1e-09 36.3 0.0 0.0086 16.0 0.0 4.0 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 GAX10127.1 - 1e-05 25.0 0.3 0.063 12.5 0.1 4.0 4 1 1 5 5 5 2 Rab3 GTPase-activating protein regulatory subunit N-terminus IKI3 PF04762.12 GAX10127.1 - 0.00018 19.7 0.2 0.04 11.9 0.0 3.3 3 1 0 4 4 4 1 IKI3 family PD40 PF07676.12 GAX10127.1 - 0.00092 19.1 1.4 0.21 11.6 0.1 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 GAX10127.1 - 0.014 14.4 0.1 8.6 5.2 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_1 PF01344.25 GAX10127.1 - 0.048 13.2 0.0 5.2 6.7 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Cytochrom_D1 PF02239.16 GAX10127.1 - 0.062 11.8 0.1 3.6 6.0 0.1 3.2 2 1 1 3 3 3 0 Cytochrome D1 heme domain Peptidase_C2 PF00648.21 GAX10128.1 - 2.5e-40 138.4 0.1 4.2e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.18 GAX10128.1 - 3.1e-06 27.2 10.0 9.8e-06 25.6 0.6 2.6 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 GAX10128.1 - 3.6e-06 27.3 0.0 0.015 15.6 0.0 2.5 2 0 0 2 2 2 2 Calpain large subunit, domain III Vta1 PF04652.16 GAX10128.1 - 0.039 13.9 1.2 0.09 12.7 1.2 1.6 1 1 0 1 1 1 0 Vta1 like UCH PF00443.29 GAX10129.1 - 2.7e-47 161.4 0.0 5.5e-47 160.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX10129.1 - 3.1e-16 59.9 9.2 9.2e-13 48.5 0.0 3.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Fer4_10 PF13237.6 GAX10129.1 - 1.4 9.1 4.1 4.6 7.4 4.1 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA PF00004.29 GAX10130.1 - 4.9e-13 49.6 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 GAX10130.1 - 1.8e-11 44.0 0.1 1.8e-11 44.0 0.1 2.1 2 1 0 2 2 1 1 AAA lid domain Mg_chelatase PF01078.21 GAX10130.1 - 0.00033 20.1 0.3 0.004 16.6 0.2 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 GAX10130.1 - 0.0021 18.3 1.7 0.34 11.2 0.2 2.9 2 1 1 3 3 3 1 AAA domain NTPase_1 PF03266.15 GAX10130.1 - 0.0024 17.8 0.2 0.0054 16.7 0.2 1.6 1 0 0 1 1 1 1 NTPase CbiA PF01656.23 GAX10130.1 - 0.0025 17.9 1.1 0.039 14.0 0.1 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ComJ PF11033.8 GAX10130.1 - 0.0025 17.5 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Competence protein J (ComJ) ResIII PF04851.15 GAX10130.1 - 0.0035 17.4 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAX10130.1 - 0.0042 17.4 0.8 0.024 15.0 0.4 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAX10130.1 - 0.0085 15.8 0.4 0.023 14.4 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 GAX10130.1 - 0.0087 15.8 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAX10130.1 - 0.009 16.0 1.2 0.018 15.1 0.1 2.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 GAX10130.1 - 0.013 14.7 1.1 0.13 11.5 1.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.12 GAX10130.1 - 0.015 14.9 0.6 0.89 9.2 0.1 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.22 GAX10130.1 - 0.018 15.4 0.0 0.051 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Nsp1_C PF05064.13 GAX10130.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region TrwB_AAD_bind PF10412.9 GAX10130.1 - 0.024 13.6 0.1 0.047 12.6 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 GAX10130.1 - 0.027 14.7 0.1 0.027 14.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX10130.1 - 0.031 14.8 0.0 0.031 14.8 0.0 3.6 3 1 1 4 4 4 0 AAA domain KTI12 PF08433.10 GAX10130.1 - 0.04 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MipZ PF09140.11 GAX10130.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ APS_kinase PF01583.20 GAX10130.1 - 0.049 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 GAX10130.1 - 0.059 12.9 1.1 0.48 10.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX10130.1 - 0.07 13.3 0.0 0.07 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 GAX10130.1 - 0.098 11.6 0.1 0.21 10.5 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 GAX10130.1 - 0.14 11.9 0.0 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 GAX10130.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.3 2 1 1 3 3 3 0 AAA ATPase domain AAA_11 PF13086.6 GAX10130.1 - 0.21 11.3 1.1 0.73 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_15 PF13429.6 GAX10131.1 - 0.0011 18.2 0.0 0.0025 17.1 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10131.1 - 0.051 13.7 0.6 1.2 9.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Voltage_CLC PF00654.20 GAX10132.1 - 0.056 12.7 0.9 0.079 12.2 0.9 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel DUF1926 PF09095.11 GAX10133.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) Sec23_trunk PF04811.15 GAX10134.1 - 4.7e-55 186.8 0.0 4.3e-54 183.6 0.0 2.0 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX10134.1 - 7.6e-25 86.7 0.4 2.7e-24 84.9 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAX10134.1 - 1.7e-23 83.2 0.0 3.7e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAX10134.1 - 2.3e-16 59.6 7.6 4.3e-16 58.7 7.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAX10134.1 - 2.4e-10 40.2 0.0 4.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAX10134.1 - 0.014 14.8 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain NIF PF03031.18 GAX10136.1 - 3.5e-53 179.6 0.3 5.2e-53 179.0 0.3 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAX10136.1 - 0.00072 20.0 0.2 0.0049 17.3 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Wzy_C_2 PF11846.8 GAX10137.1 - 0.058 13.3 0.3 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_14 PF13428.6 GAX10138.1 - 1.7e-08 34.6 5.5 0.077 13.9 0.0 6.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX10138.1 - 1e-05 25.9 0.6 1.9 9.0 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10138.1 - 8.3e-05 22.4 11.7 5.8 7.3 0.6 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10138.1 - 0.00018 22.1 3.4 5.8 7.7 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10138.1 - 0.0017 18.4 5.0 17 6.0 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10138.1 - 0.014 15.1 0.2 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 GAX10138.1 - 0.05 13.9 5.1 0.081 13.2 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX10138.1 - 0.13 13.0 1.3 13 6.8 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX10138.1 - 0.23 11.4 0.9 13 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10138.1 - 6.1 7.1 7.8 1.4 9.2 0.4 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.8 GAX10139.1 - 0.00022 21.4 5.0 0.00022 21.4 5.0 12.3 6 4 4 10 10 10 1 TATA element modulatory factor 1 TATA binding Nup54 PF13874.6 GAX10139.1 - 0.011 15.8 0.7 0.011 15.8 0.7 9.8 4 3 5 9 9 9 0 Nucleoporin complex subunit 54 UvrA_DNA-bind PF17755.1 GAX10139.1 - 0.078 13.3 5.3 0.19 12.1 0.3 3.6 3 0 0 3 3 3 0 UvrA DNA-binding domain MFS_5 PF05631.14 GAX10140.1 - 4.9e-74 249.4 4.0 8.1e-74 248.6 4.0 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAX10140.1 - 4.7e-16 58.7 21.6 9e-16 57.7 21.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAX10140.1 - 0.00018 20.2 1.4 0.00018 20.2 1.4 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein IMPDH PF00478.25 GAX10141.1 - 1.8e-134 448.1 1.1 2.1e-134 447.9 1.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 GAX10141.1 - 3.2e-13 49.9 0.0 3.5e-05 24.2 0.0 3.4 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 GAX10141.1 - 3.4e-10 39.8 0.9 5.8e-07 29.2 0.3 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 GAX10141.1 - 2.3e-06 26.9 14.0 5e-05 22.5 12.2 2.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 GAX10141.1 - 0.00027 20.3 3.4 0.03 13.7 0.4 2.5 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAX10141.1 - 0.0034 16.9 0.5 0.023 14.2 0.5 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 GAX10141.1 - 0.004 16.4 2.5 0.13 11.4 2.5 3.1 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 GAX10141.1 - 0.017 14.3 3.7 0.039 13.1 1.2 2.3 2 0 0 2 2 2 0 Conserved region in glutamate synthase Aldolase PF01081.19 GAX10141.1 - 0.028 13.8 1.5 0.11 11.9 0.1 2.3 3 0 0 3 3 3 0 KDPG and KHG aldolase TMP-TENI PF02581.17 GAX10141.1 - 0.044 13.1 0.9 1.8 7.9 0.4 2.4 1 1 1 2 2 2 0 Thiamine monophosphate synthase Methyltransf_3 PF01596.17 GAX10143.1 - 5.5e-14 51.8 0.1 2.6e-13 49.6 0.1 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAX10143.1 - 5.2e-07 30.7 0.0 1.1e-06 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CSF-1 PF05337.11 GAX10143.1 - 0.14 12.2 0.1 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) DAGAT PF03982.13 GAX10144.1 - 2.2e-39 135.2 0.1 2.7e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GAX10144.1 - 2.6e-05 23.9 0.0 5.5e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 GAX10145.1 - 9.7e-44 149.5 0.1 1.2e-43 149.2 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GAX10145.1 - 2e-07 30.7 0.0 3.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ABC_membrane_2 PF06472.15 GAX10145.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 PAP_fibrillin PF04755.12 GAX10146.1 - 1.7e-12 47.7 0.0 2.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin DUF4792 PF16040.5 GAX10147.1 - 5.1e-07 29.5 0.7 2e-06 27.6 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4792) DUF4793 PF16041.5 GAX10147.1 - 1.9e-05 24.8 0.2 4.9e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) His_Phos_2 PF00328.22 GAX10148.1 - 4.8e-08 32.8 0.0 4e-06 26.4 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) Exo_endo_phos PF03372.23 GAX10149.1 - 4.5e-23 82.0 0.6 1e-22 80.8 0.6 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 GAX10149.1 - 0.004 17.4 3.1 0.0088 16.3 3.1 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Exo_endo_phos_2 PF14529.6 GAX10149.1 - 0.069 13.0 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase HopJ PF08888.11 GAX10150.1 - 1.7e-39 134.4 0.0 2.5e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 HopJ type III effector protein Abhydrolase_6 PF12697.7 GAX10151.1 - 3.5e-22 80.1 0.1 4.4e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX10151.1 - 1.8e-17 63.4 0.0 2.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX10151.1 - 5e-10 39.5 0.1 6.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GAX10151.1 - 0.0025 17.6 0.0 0.07 12.9 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 GAX10151.1 - 0.0038 17.2 0.0 0.11 12.4 0.0 2.4 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 GAX10151.1 - 0.0068 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 GAX10151.1 - 0.1 12.1 0.0 2 7.9 0.0 2.3 2 1 1 3 3 3 0 Dienelactone hydrolase family TAXi_N PF14543.6 GAX10153.1 - 1.5e-19 70.9 1.3 4.8e-19 69.3 0.2 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX10153.1 - 2.7e-15 56.6 0.7 5.3e-10 39.2 0.2 3.0 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX10153.1 - 0.00015 21.6 0.1 0.056 13.2 0.0 2.6 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Inositol_P PF00459.25 GAX10154.1 - 3.7e-56 190.6 0.0 4.8e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 GAX10154.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 GAX10155.1 - 1.5e-30 106.7 0.1 4.3e-30 105.2 0.1 1.7 1 1 1 2 2 2 1 Inositol monophosphatase family CN_hydrolase PF00795.22 GAX10155.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase PBP1_TM PF14812.6 GAX10155.1 - 0.17 12.3 2.9 0.32 11.4 2.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chloroa_b-bind PF00504.21 GAX10156.1 - 2.3e-20 73.7 0.0 3.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DAHP_synth_2 PF01474.16 GAX10157.1 - 2.3e-193 642.7 0.0 2.6e-193 642.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Tsi6 PF18660.1 GAX10157.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Tsi6 Proteasome PF00227.26 GAX10158.1 - 2.6e-44 151.0 0.1 3.5e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX10158.1 - 3.4e-09 36.2 1.4 3.9e-09 36.0 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature COQ9 PF08511.11 GAX10158.1 - 0.0091 15.7 0.0 6.3 6.6 0.0 2.4 2 0 0 2 2 2 2 COQ9 DUF5018 PF16410.5 GAX10158.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Stap_Strp_toxin PF01123.20 GAX10160.1 - 0.16 12.8 0.2 21 6.1 0.2 2.6 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain Ank_2 PF12796.7 GAX10161.1 - 5.2e-27 94.3 0.7 1.4e-09 38.4 0.0 6.4 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX10161.1 - 8.8e-16 58.1 8.3 0.0046 17.5 0.0 9.1 6 3 4 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX10161.1 - 3.1e-14 51.7 7.2 0.11 13.1 0.0 10.1 11 0 0 11 11 11 2 Ankyrin repeat Ank_5 PF13857.6 GAX10161.1 - 5.7e-14 52.0 3.2 1 9.8 0.0 8.0 4 3 4 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 GAX10161.1 - 1.1e-12 47.8 6.8 0.23 12.0 0.0 9.8 10 0 0 10 10 10 3 Ankyrin repeat RICTOR_V PF14668.6 GAX10162.1 - 0.0017 18.6 0.0 0.12 12.7 0.0 3.1 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.23 GAX10162.1 - 0.3 11.2 12.5 3.9 7.7 0.0 5.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HSF_DNA-bind PF00447.17 GAX10163.1 - 2.4e-09 37.7 0.0 3.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding EF-hand_7 PF13499.6 GAX10165.1 - 0.16 12.5 0.1 0.34 11.4 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 GAX10165.1 - 0.18 11.4 0.4 1.1 9.0 0.1 2.2 1 1 1 2 2 2 0 EF hand HisKA PF00512.25 GAX10165.1 - 0.31 11.1 1.4 4.5 7.4 1.4 2.4 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain zf-SNAP50_C PF12251.8 GAX10166.1 - 1.7e-14 54.0 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal MtN3_slv PF03083.16 GAX10167.1 - 4.5e-23 81.1 5.7 1.5e-13 50.6 1.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Proteasome PF00227.26 GAX10168.1 - 8e-41 139.6 0.2 2e-40 138.3 0.2 1.6 1 1 0 1 1 1 1 Proteasome subunit NIF PF03031.18 GAX10169.1 - 2.5e-43 147.5 0.0 3.7e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 GAX10169.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF705) GLTP PF08718.11 GAX10170.1 - 2.3e-14 53.9 0.0 3.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GLTP PF08718.11 GAX10171.1 - 1.7e-19 70.6 0.1 2.8e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) AKNA PF12443.8 GAX10171.1 - 0.14 12.9 0.0 22 5.8 0.0 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor ABC2_membrane PF01061.24 GAX10172.1 - 8.4e-75 250.8 55.4 2.4e-38 131.7 24.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAX10172.1 - 9.9e-42 142.7 0.0 9.5e-22 78.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 GAX10172.1 - 6.7e-08 32.3 0.1 0.00048 19.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 GAX10172.1 - 9.8e-08 32.1 0.6 0.00036 20.5 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 GAX10172.1 - 2.2e-07 31.0 0.0 0.57 9.9 0.0 3.5 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX10172.1 - 2.6e-07 30.3 2.1 0.0095 15.7 0.6 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX10172.1 - 4e-06 27.1 0.1 0.068 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAX10172.1 - 2.1e-05 25.0 0.2 0.19 12.1 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 GAX10172.1 - 3.7e-05 24.3 2.1 0.25 11.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 GAX10172.1 - 0.00011 21.8 0.7 1.3 8.5 0.1 3.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 GAX10172.1 - 0.00029 20.0 16.9 0.00029 20.0 16.9 3.6 2 2 1 3 3 3 2 ABC-2 family transporter protein AAA_18 PF13238.6 GAX10172.1 - 0.00053 20.5 0.2 1.6 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 GAX10172.1 - 0.0006 19.1 1.1 0.082 12.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 GAX10172.1 - 0.00086 19.3 2.5 0.16 11.9 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 GAX10172.1 - 0.0012 19.0 0.6 1.5 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 GAX10172.1 - 0.0016 18.1 0.9 1.4 8.4 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 GAX10172.1 - 0.002 17.9 0.2 0.12 12.1 0.0 2.9 4 0 0 4 4 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 GAX10172.1 - 0.0031 17.2 5.5 0.46 10.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 GAX10172.1 - 0.0044 16.8 0.7 3.1 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAX10172.1 - 0.0057 16.7 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 GAX10172.1 - 0.0068 16.3 0.8 0.49 10.3 0.0 2.8 3 0 0 3 3 2 1 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 GAX10172.1 - 0.0094 16.3 0.6 0.74 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAX10172.1 - 0.0094 16.2 0.5 6.1 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX10172.1 - 0.01 16.2 1.8 4.7 7.7 0.1 3.5 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 GAX10172.1 - 0.013 15.0 1.1 5.4 6.5 0.1 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 GAX10172.1 - 0.013 15.9 1.7 4.1 7.8 0.1 3.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 GAX10172.1 - 0.013 14.5 0.1 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 GAX10172.1 - 0.018 15.0 1.9 5 7.1 0.3 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 GAX10172.1 - 0.019 14.7 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 GAX10172.1 - 0.043 13.7 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 GAX10172.1 - 0.059 13.8 1.1 1.3 9.4 0.1 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 GAX10172.1 - 0.12 12.3 0.3 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 NTPase G-alpha PF00503.20 GAX10172.1 - 0.13 11.4 0.0 0.86 8.7 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 GAX10172.1 - 0.18 11.9 7.9 1 9.4 0.2 3.1 2 1 1 3 3 3 0 Helicase HerA, central domain NB-ARC PF00931.22 GAX10172.1 - 0.18 11.0 1.0 6 6.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 GAX10172.1 - 0.19 11.4 1.4 31 4.1 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 GAX10172.1 - 0.22 11.3 1.9 1.5 8.5 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF5056 PF16479.5 GAX10172.1 - 0.56 10.5 3.4 20 5.5 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) 5_nucleotid PF05761.14 GAX10173.1 - 6.6e-109 364.8 0.0 2.9e-78 263.8 0.0 2.1 2 0 0 2 2 2 2 5' nucleotidase family Hydrolase_like PF13242.6 GAX10173.1 - 0.012 15.6 0.1 0.041 13.9 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like Cupin_4 PF08007.12 GAX10174.1 - 3.6e-18 66.1 0.2 1.9e-17 63.8 0.2 1.8 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 GAX10174.1 - 1.1e-12 48.2 0.1 3.3e-12 46.7 0.0 1.8 2 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 GAX10174.1 - 0.0016 18.1 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Cupin domain EMC1_C PF07774.13 GAX10175.1 - 1.1e-57 195.1 0.0 1.8e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 GAX10175.1 - 1.4e-07 31.3 3.4 1.8e-07 31.0 0.9 2.4 3 0 0 3 3 3 1 PQQ-like domain IBR PF01485.21 GAX10176.1 - 2.5e-08 34.0 19.4 2.6e-06 27.5 3.3 4.8 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain CUE PF02845.16 GAX10176.1 - 0.0025 17.5 0.1 0.0074 16.0 0.1 1.8 1 0 0 1 1 1 1 CUE domain Sgf11 PF08209.11 GAX10177.1 - 1.8e-12 46.6 0.1 2.6e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 GAX10177.1 - 0.00076 19.3 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 zinc-finger of a C2HC-type FlaC_arch PF05377.11 GAX10178.1 - 0.055 13.9 3.6 1.5 9.3 0.3 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 GAX10178.1 - 0.078 13.2 0.2 2.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CCT PF06203.14 GAX10179.1 - 1.4e-15 57.1 11.1 2.9e-15 56.0 11.1 1.6 1 0 0 1 1 1 1 CCT motif DUF5568 PF17724.1 GAX10179.1 - 0.082 12.7 1.9 0.15 11.8 1.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5568) NARP1 PF12569.8 GAX10179.1 - 0.32 9.8 7.1 0.49 9.2 7.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U1snRNP70_N PF12220.8 GAX10179.1 - 1.4 9.6 8.4 5.5 7.7 7.6 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CortBP2 PF09727.9 GAX10179.1 - 2.4 8.0 12.3 1.6 8.6 9.9 1.8 2 0 0 2 2 2 0 Cortactin-binding protein-2 BSD PF03909.17 GAX10180.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 BSD domain Aminotran_1_2 PF00155.21 GAX10181.1 - 2.5e-52 178.3 0.0 3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAX10181.1 - 4.3e-07 29.5 0.2 1.5e-06 27.7 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAX10181.1 - 7.7e-07 28.7 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAX10181.1 - 4.3e-05 22.6 0.0 7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 GAX10181.1 - 0.00016 20.6 0.0 0.00025 19.9 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 GAX10181.1 - 0.0055 15.3 0.0 0.0098 14.5 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CitMHS PF03600.16 GAX10182.1 - 7.3e-27 94.3 2.4 1.2e-26 93.6 0.9 1.9 1 1 1 2 2 2 1 Citrate transporter PDR_CDR PF06422.12 GAX10182.1 - 0.72 9.8 6.5 3.6 7.6 0.2 3.0 2 0 0 2 2 2 0 CDR ABC transporter DUF974 PF06159.13 GAX10183.1 - 6.4e-43 147.3 0.0 8.6e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 GAX10183.1 - 0.1 12.0 0.2 4.3 6.7 0.2 2.6 2 1 0 2 2 2 0 TRAPP trafficking subunit Trs65 RPEL PF02755.15 GAX10183.1 - 0.2 11.4 0.6 0.49 10.2 0.6 1.6 1 0 0 1 1 1 0 RPEL repeat MMS1_N PF10433.9 GAX10184.1 - 8.8e-117 390.7 0.0 3.2e-116 388.9 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAX10184.1 - 7.7e-76 255.5 0.0 1.3e-75 254.7 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region NOA36 PF06524.12 GAX10184.1 - 6.2 6.1 8.2 11 5.3 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein MutS_V PF00488.21 GAX10185.1 - 5.7e-70 235.2 0.0 1.1e-69 234.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAX10185.1 - 4.5e-29 102.1 0.3 1.2e-28 100.7 0.0 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 GAX10185.1 - 1.3e-28 99.5 0.1 3.1e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain I YL1 PF05764.13 GAX10185.1 - 0.00021 21.5 14.3 0.00048 20.3 14.3 1.6 1 0 0 1 1 1 1 YL1 nuclear protein MutS_II PF05188.17 GAX10185.1 - 0.00043 20.6 0.0 0.0075 16.6 0.0 3.1 2 1 0 2 2 2 1 MutS domain II SDA1 PF05285.12 GAX10185.1 - 0.0069 15.9 18.8 0.012 15.1 18.8 1.3 1 0 0 1 1 1 1 SDA1 DUF4746 PF15928.5 GAX10185.1 - 0.11 11.8 15.0 0.24 10.8 14.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 GAX10185.1 - 0.37 8.9 23.1 0.57 8.3 23.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAX10185.1 - 0.63 9.3 22.4 1.7 7.9 22.4 1.6 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAX10185.1 - 2.9 6.1 17.2 5.2 5.2 17.2 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA_23 PF13476.6 GAX10185.1 - 3.1 8.2 15.0 8.1 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Roughex PF06020.11 GAX10185.1 - 5.4 6.0 11.0 9.4 5.2 11.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Rubredoxin_2 PF18073.1 GAX10186.1 - 0.046 13.5 0.1 0.046 13.5 0.1 3.7 4 0 0 4 4 4 0 Rubredoxin metal binding domain zf-CHY PF05495.12 GAX10186.1 - 1.6 9.3 23.1 0.35 11.4 3.4 4.0 2 2 1 3 3 3 0 CHY zinc finger Hemerythrin PF01814.23 GAX10189.1 - 9.1e-06 26.3 1.9 0.0039 17.8 0.2 2.3 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain Dynactin_p22 PF07426.11 GAX10189.1 - 0.061 13.2 1.1 3.5 7.4 0.2 2.2 2 0 0 2 2 2 0 Dynactin subunit p22 PAP_fibrillin PF04755.12 GAX10190.1 - 2.9e-17 63.3 0.0 4.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin LRR_6 PF13516.6 GAX10191.1 - 5.5e-18 63.4 14.2 0.49 10.6 0.4 11.2 12 0 0 12 12 12 8 Leucine Rich repeat LRR_1 PF00560.33 GAX10191.1 - 3.2e-06 26.9 16.2 6 7.8 1.0 9.6 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.7 GAX10191.1 - 6.1e-05 23.3 25.2 0.39 11.2 0.1 7.4 4 3 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX10191.1 - 0.044 13.5 22.0 8.5 6.2 0.1 8.0 6 1 3 9 9 9 0 Leucine rich repeat TBP PF00352.21 GAX10192.1 - 1.2e-59 198.3 0.6 1.4e-29 101.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) PP2C PF00481.21 GAX10193.1 - 1.2e-39 136.6 0.0 1.5e-19 70.7 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C PH PF00169.29 GAX10193.1 - 5.6e-07 30.0 0.3 6e-06 26.7 0.1 2.6 1 1 1 2 2 2 1 PH domain PH_11 PF15413.6 GAX10193.1 - 0.00043 20.7 0.1 0.096 13.1 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain OMP_b-brl_3 PF14905.6 GAX10193.1 - 0.0096 14.9 0.2 0.016 14.2 0.2 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family PH_9 PF15410.6 GAX10193.1 - 0.048 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain CDV3 PF15359.6 GAX10193.1 - 0.48 10.9 7.7 4 7.9 7.3 2.5 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 SPRR2 PF14820.6 GAX10193.1 - 0.6 10.2 6.6 1.4 9.0 6.6 1.7 1 0 0 1 1 1 0 Small proline-rich 2 PQ-loop PF04193.14 GAX10194.1 - 2.1e-29 101.1 8.9 7.2e-16 57.7 2.3 3.1 4 0 0 4 4 4 2 PQ loop repeat DUF805 PF05656.14 GAX10194.1 - 1 9.8 4.8 0.59 10.6 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF202 PF02656.15 GAX10194.1 - 4.4 7.8 5.8 18 5.9 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) LON_substr_bdg PF02190.16 GAX10195.1 - 2.3e-11 44.0 0.0 6e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 GAX10195.1 - 4.6e-05 23.6 0.0 0.00012 22.2 0.0 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NADH_Oxid_Nqo15 PF11497.8 GAX10195.1 - 0.08 13.0 0.4 13 5.9 0.1 2.4 1 1 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 TIMELESS PF04821.14 GAX10196.1 - 6.6e-56 189.6 1.5 1.8e-55 188.1 1.5 1.8 1 0 0 1 1 1 1 Timeless protein Vta1 PF04652.16 GAX10196.1 - 0.048 13.6 1.0 0.67 9.9 0.8 2.9 2 1 1 3 3 3 0 Vta1 like RPAP3_C PF13877.6 GAX10196.1 - 0.056 14.0 2.5 0.38 11.3 0.3 2.8 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 TMEM144 PF07857.12 GAX10197.1 - 8.7e-17 61.1 21.1 5.4e-11 42.0 0.9 2.9 2 1 0 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 GAX10197.1 - 0.0014 18.0 21.6 0.031 13.6 7.4 2.3 2 1 0 2 2 2 2 Sugar transport protein DUF4726 PF15855.5 GAX10197.1 - 0.18 12.1 0.1 0.29 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) PEP-CTERM PF07589.11 GAX10197.1 - 5.6 7.2 7.6 15 5.8 0.3 4.3 3 0 0 3 3 3 0 PEP-CTERM motif LPP PF04728.13 GAX10198.1 - 0.00043 20.6 3.1 0.00043 20.6 3.1 6.6 9 1 0 9 9 9 2 Lipoprotein leucine-zipper UPF0449 PF15136.6 GAX10198.1 - 0.0016 18.8 0.9 0.0016 18.8 0.9 5.6 4 3 3 7 7 7 1 Uncharacterised protein family UPF0449 Cupin_8 PF13621.6 GAX10199.1 - 0.048 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Cupin-like domain FMN_red PF03358.15 GAX10200.1 - 1.3e-09 38.0 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 GAX10200.1 - 0.00016 21.9 0.4 0.0016 18.6 0.4 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 GAX10200.1 - 0.027 14.2 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold Peptidase_A22B PF04258.13 GAX10201.1 - 7.6e-61 206.1 4.1 1.1e-60 205.5 4.1 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 GAX10201.1 - 1.6e-05 24.9 0.0 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 1 PA domain DUF4239 PF14023.6 GAX10202.1 - 7.1e-51 173.0 0.7 1e-50 172.4 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) KNTase_C PF07827.11 GAX10202.1 - 0.1 12.4 0.0 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 KNTase C-terminal domain GerD PF17898.1 GAX10204.1 - 0.0047 16.9 15.5 0.0058 16.6 13.5 2.1 1 1 1 2 2 2 1 Spore germination GerD central core domain DUF2379 PF09543.10 GAX10204.1 - 0.03 14.5 2.5 0.043 14.0 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2379) SpoOE-like PF09388.10 GAX10204.1 - 0.084 12.8 1.8 3 7.8 0.4 2.9 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein MCU PF04678.13 GAX10204.1 - 0.1 12.7 7.4 0.16 12.1 7.4 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter STI1 PF17830.1 GAX10204.1 - 0.11 12.5 17.4 1.1 9.3 5.2 3.2 1 1 2 3 3 3 0 STI1 domain DUF1974 PF09317.11 GAX10204.1 - 0.81 9.2 8.6 0.96 9.0 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Ndc1_Nup PF09531.10 GAX10204.1 - 1.2 7.8 4.5 1.2 7.7 4.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ku_C PF03730.14 GAX10204.1 - 5.5 7.8 15.1 4.9 7.9 13.8 1.6 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm PCRF PF03462.18 GAX10204.1 - 7.2 6.4 14.5 9.9 6.0 14.5 1.3 1 0 0 1 1 1 0 PCRF domain Metallophos PF00149.28 GAX10205.1 - 4.9e-08 33.7 3.3 7.1e-08 33.2 3.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 GAX10205.1 - 0.00021 21.6 0.0 0.00038 20.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain LtrA PF06772.11 GAX10205.1 - 0.081 12.1 1.0 0.17 11.1 1.0 1.4 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) DUF4033 PF13225.6 GAX10207.1 - 2.4e-34 117.2 1.1 3.7e-34 116.6 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4033) TMEM154 PF15102.6 GAX10208.1 - 0.0022 17.9 0.4 0.0079 16.1 0.4 1.9 1 1 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.12 GAX10208.1 - 0.063 12.8 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 CD34/Podocalyxin family mTERF PF02536.14 GAX10209.1 - 3.7e-17 62.2 2.8 0.00075 18.5 0.1 4.7 1 1 0 2 2 2 2 mTERF LuxT_C PF18285.1 GAX10209.1 - 0.041 14.4 0.1 0.15 12.6 0.1 2.1 1 1 1 2 2 2 0 Tetracycline repressor LuxT C-terminal domain GCHY-1 PF02649.14 GAX10209.1 - 0.077 12.5 0.8 0.11 12.0 0.2 1.5 2 0 0 2 2 2 0 Type I GTP cyclohydrolase folE2 NICE-3 PF07406.11 GAX10209.1 - 0.12 12.4 1.2 0.36 10.8 1.2 1.8 1 0 0 1 1 1 0 NICE-3 protein Cnd1 PF12717.7 GAX10209.1 - 0.12 12.4 0.7 0.45 10.5 0.2 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Autophagy_N PF03986.13 GAX10210.1 - 3.6e-37 127.4 0.3 5.7e-37 126.7 0.3 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 GAX10210.1 - 1.3e-18 67.4 0.1 2.5e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 GAX10210.1 - 1.3e-12 47.0 4.5 2.6e-12 46.0 4.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Ribosomal_S8e PF01201.22 GAX10211.1 - 5.4e-54 182.1 0.5 6.2e-54 181.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e eIF-1a PF01176.19 GAX10212.1 - 2.7e-23 81.5 0.3 3.7e-23 81.1 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Acetyltransf_1 PF00583.25 GAX10213.1 - 3.9e-10 40.0 0.1 6.4e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX10213.1 - 2.2e-07 30.8 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX10213.1 - 8.1e-07 29.4 0.1 1.3e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAX10213.1 - 2.2e-05 25.2 0.0 2.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 GAX10213.1 - 4e-05 23.3 0.0 6.6e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 GAX10213.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAX10213.1 - 0.00021 21.5 0.0 0.00029 21.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SET PF00856.28 GAX10214.1 - 1.8e-13 51.2 0.5 1.8e-13 51.2 0.5 3.1 2 1 0 2 2 2 1 SET domain PHD PF00628.29 GAX10214.1 - 6.7e-07 29.1 10.8 6.7e-07 29.1 10.8 4.4 4 0 0 4 4 4 1 PHD-finger Bromodomain PF00439.25 GAX10214.1 - 3.1e-05 24.0 0.0 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 Bromodomain ATPase-cat_bd PF12156.8 GAX10214.1 - 0.011 16.4 1.1 0.011 16.4 1.1 3.4 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase Evr1_Alr PF04777.13 GAX10214.1 - 0.13 12.8 2.0 0.96 10.0 1.0 2.8 2 0 0 2 2 2 0 Erv1 / Alr family DUF4205 PF13898.6 GAX10215.1 - 3.1e-38 131.6 0.0 1.8e-34 119.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) TPR_2 PF07719.17 GAX10216.1 - 1.2e-07 31.2 4.2 0.013 15.5 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10216.1 - 2.4e-07 30.3 2.7 0.001 18.8 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10216.1 - 3.2e-05 23.8 0.9 0.045 14.0 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10216.1 - 0.00093 18.8 0.7 0.3 10.8 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.6 GAX10216.1 - 0.17 12.0 2.3 6.9 6.9 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX10216.1 - 0.35 11.8 0.0 0.35 11.8 0.0 4.8 5 2 1 6 6 6 0 Tetratricopeptide repeat GlcNAc PF11397.8 GAX10218.1 - 2.6e-37 129.1 0.0 3.3e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Pkinase PF00069.25 GAX10219.1 - 2.1e-48 165.0 0.0 2.9e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10219.1 - 5.4e-20 71.8 0.2 1.9e-19 69.9 0.2 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX10219.1 - 3.3e-06 26.6 2.0 1.3e-05 24.6 2.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX10219.1 - 0.00052 19.4 0.6 0.0013 18.1 0.6 1.7 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 GAX10219.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 GAX10219.1 - 0.014 14.2 0.1 0.021 13.6 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 GAX10219.1 - 0.11 12.1 0.4 0.54 9.8 0.2 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase FTA2 PF13095.6 GAX10219.1 - 0.13 11.9 0.4 0.3 10.7 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 COPIIcoated_ERV PF07970.12 GAX10221.1 - 1.4e-64 218.0 0.2 2.1e-64 217.4 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX10221.1 - 1.4e-05 25.3 0.2 2.8e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PP-binding PF00550.25 GAX10222.1 - 8.3e-14 51.7 0.4 1.1e-13 51.3 0.4 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAX10222.1 - 6e-05 23.2 0.3 8.2e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF760 PF05542.11 GAX10223.1 - 1.8e-39 134.0 0.4 7.9e-19 67.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) TPR_12 PF13424.6 GAX10224.1 - 6.5e-33 112.9 21.0 9.7e-11 41.8 0.2 8.3 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10224.1 - 1.6e-28 97.3 9.0 1.9e-06 27.5 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10224.1 - 8.8e-22 75.4 19.2 0.00013 21.8 0.1 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10224.1 - 1e-16 59.7 13.9 0.00025 21.0 0.1 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX10224.1 - 6.6e-16 57.6 20.0 4.8e-05 23.1 0.0 9.2 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX10224.1 - 1.7e-14 52.6 14.0 3.8e-07 29.7 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10224.1 - 6.2e-06 26.8 10.0 0.038 14.6 0.0 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX10224.1 - 1.5e-05 25.3 10.6 0.18 12.5 0.1 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX10224.1 - 6.2e-05 23.5 9.7 2 9.5 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX10224.1 - 8e-05 22.2 0.6 1.5 8.1 0.2 3.5 2 1 1 3 3 3 2 MalT-like TPR region TPR_11 PF13414.6 GAX10224.1 - 0.011 15.4 8.0 1.2 8.9 0.2 5.2 6 0 0 6 6 6 0 TPR repeat TPR_17 PF13431.6 GAX10224.1 - 0.011 16.0 8.8 19 5.9 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat PUFD PF16553.5 GAX10224.1 - 0.049 13.7 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain Med2 PF11214.8 GAX10224.1 - 0.075 13.2 0.1 0.25 11.5 0.1 1.9 1 0 0 1 1 1 0 Mediator complex subunit 2 TPR_3 PF07720.12 GAX10224.1 - 0.099 12.7 1.4 0.43 10.6 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 GAX10225.1 - 4.4e-39 133.9 0.0 9.5e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAX10225.1 - 5.1e-18 64.8 0.2 1.2e-17 63.6 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAX10225.1 - 1e-11 44.5 0.2 2.5e-11 43.2 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAX10225.1 - 1.5e-06 28.2 0.2 1.5e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX10225.1 - 1.6e-06 28.3 0.0 6e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAX10225.1 - 1.3e-05 25.7 0.2 5.5e-05 23.6 0.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX10225.1 - 5.6e-05 23.4 0.1 0.0018 18.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAX10225.1 - 0.00016 21.5 0.2 0.00082 19.1 0.2 2.1 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 GAX10225.1 - 0.0015 18.4 1.5 0.097 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX10225.1 - 0.0019 18.4 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF812 PF05667.11 GAX10225.1 - 0.0086 15.0 1.5 0.013 14.4 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_3 PF07726.11 GAX10225.1 - 0.013 15.4 0.5 0.044 13.7 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAX10225.1 - 0.013 15.2 0.1 0.076 12.7 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 GAX10225.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 GAX10225.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAX10225.1 - 0.032 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 GAX10225.1 - 0.046 13.2 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Transcrip_act PF04949.13 GAX10225.1 - 0.077 12.9 3.8 0.044 13.7 1.1 1.9 2 0 0 2 2 2 0 Transcriptional activator CPT PF07931.12 GAX10225.1 - 0.079 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MPS2 PF17060.5 GAX10225.1 - 0.09 12.0 2.5 0.16 11.2 2.5 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 AAA_7 PF12775.7 GAX10225.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Atg14 PF10186.9 GAX10225.1 - 0.1 11.7 2.9 0.19 10.8 2.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATPase PF06745.13 GAX10225.1 - 0.11 11.8 0.5 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 GAX10225.1 - 0.16 12.5 1.2 0.76 10.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 GAX10225.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAX10225.1 - 0.24 11.9 2.1 5 7.6 0.0 2.6 2 0 0 2 2 2 0 ABC transporter BAF PF02961.14 GAX10227.1 - 1.8e-05 25.1 0.0 3.2e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Barrier to autointegration factor HHH_5 PF14520.6 GAX10227.1 - 0.069 13.8 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain MMR_HSR1 PF01926.23 GAX10228.1 - 5.8e-21 74.7 0.0 9.3e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX10228.1 - 2.7e-07 30.3 0.0 3.5e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 GAX10228.1 - 7.5e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 GAX10228.1 - 0.0015 18.6 0.0 0.44 10.6 0.1 2.3 1 1 1 2 2 2 2 Dynamin family PduV-EutP PF10662.9 GAX10228.1 - 0.0015 18.3 0.0 0.0084 15.9 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 GAX10228.1 - 0.0076 15.8 0.1 0.74 9.3 0.1 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX10228.1 - 0.01 15.8 0.0 0.11 12.4 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 GAX10228.1 - 0.021 15.3 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 GAX10228.1 - 0.034 14.4 0.4 0.68 10.2 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 GAX10228.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 GAX10228.1 - 0.081 13.3 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 GAX10228.1 - 0.095 12.6 0.1 6.6 6.6 0.0 2.3 2 0 0 2 2 2 0 NTPase GBP PF02263.19 GAX10228.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain FBPase PF00316.20 GAX10229.1 - 5.8e-32 110.7 0.0 9.7e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain zf-DNL PF05180.12 GAX10229.1 - 0.041 13.8 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 DNL zinc finger DUF3653 PF12375.8 GAX10229.1 - 0.044 13.9 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Phage protein Coat_F PF07875.12 GAX10229.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Coat F domain Inositol_P PF00459.25 GAX10229.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family FBPase PF00316.20 GAX10230.1 - 5.9e-45 153.1 0.2 1.2e-44 152.0 0.2 1.5 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain FBPase PF00316.20 GAX10231.1 - 2.9e-47 160.6 0.0 4e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Glycolytic PF00274.19 GAX10232.1 - 1.3e-11 43.9 0.0 1.6e-10 40.3 0.0 2.0 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-I Laminin_G_3 PF13385.6 GAX10233.1 - 1e-06 29.0 0.0 4.2e-06 27.0 0.0 2.1 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Mpv17_PMP22 PF04117.12 GAX10234.1 - 6.5e-21 74.3 0.5 1.3e-20 73.3 0.5 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Acyltransferase PF01553.21 GAX10235.1 - 3.2e-17 62.4 0.0 4.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1195 PF06708.11 GAX10236.1 - 0.0099 15.7 0.3 0.014 15.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1195) Ribosomal_L17 PF01196.19 GAX10237.1 - 1.7e-32 112.2 0.3 2.2e-32 111.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 DNA_pol3_delta2 PF13177.6 GAX10238.1 - 3.4e-15 56.2 0.0 7.9e-15 55.0 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GAX10238.1 - 1.9e-13 51.0 0.0 6.9e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 GAX10238.1 - 7.8e-12 45.4 0.2 4.1e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 GAX10238.1 - 1.3e-06 28.8 0.0 5.1e-06 26.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX10238.1 - 1.8e-06 28.5 0.7 0.0001 22.8 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain ResIII PF04851.15 GAX10238.1 - 2e-05 24.7 0.0 0.0015 18.5 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 GAX10238.1 - 2.2e-05 24.3 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 GAX10238.1 - 0.00011 22.6 0.0 0.00035 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX10238.1 - 0.00012 22.1 0.0 0.06 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 GAX10238.1 - 0.00022 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 GAX10238.1 - 0.0006 20.2 0.0 0.038 14.4 0.0 2.8 2 2 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 GAX10238.1 - 0.00064 19.2 0.0 0.0037 16.7 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GAX10238.1 - 0.00071 19.5 0.0 0.0018 18.2 0.0 1.8 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 GAX10238.1 - 0.0015 18.2 0.0 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX10238.1 - 0.0016 18.2 0.0 0.0047 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAX10238.1 - 0.0022 17.8 0.0 0.0072 16.1 0.0 1.8 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX10238.1 - 0.0033 17.2 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 GAX10238.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain ATPase_2 PF01637.18 GAX10238.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 GAX10238.1 - 0.016 14.6 0.0 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 GAX10238.1 - 0.017 14.9 0.0 0.23 11.2 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein DEAD PF00270.29 GAX10238.1 - 0.02 14.6 0.0 3 7.6 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 GAX10238.1 - 0.025 14.0 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 GAX10238.1 - 0.036 13.4 0.0 11 5.2 0.0 2.9 2 1 1 3 3 3 0 Zeta toxin TIP49 PF06068.13 GAX10238.1 - 0.039 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 GAX10238.1 - 0.042 14.0 0.0 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 GAX10238.1 - 0.044 13.9 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 GAX10238.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MeaB PF03308.16 GAX10238.1 - 0.059 12.3 0.1 0.78 8.7 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 GAX10238.1 - 0.068 13.7 0.0 0.17 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX10238.1 - 0.089 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAX10238.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Kelch_1 PF01344.25 GAX10239.1 - 8.1e-53 175.8 25.1 6.2e-11 41.7 1.9 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAX10239.1 - 5.7e-49 163.9 18.9 1.5e-10 40.9 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAX10239.1 - 1.6e-43 146.2 26.6 3e-10 40.1 0.1 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 GAX10239.1 - 6.6e-43 143.1 25.7 1.2e-09 37.7 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAX10239.1 - 8.3e-42 140.2 23.9 8.5e-09 35.4 1.4 6.3 4 1 2 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAX10239.1 - 1.5e-32 111.0 24.2 4.5e-07 29.7 0.6 6.4 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 GAX10239.1 - 1.1e-23 83.5 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BNR_2 PF13088.6 GAX10239.1 - 0.052 12.8 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 BNR repeat-like domain Sulf_transp PF04143.14 GAX10240.1 - 5.4e-10 39.3 23.9 8.7e-09 35.4 5.8 3.4 1 1 2 3 3 3 3 Sulphur transport FAM209 PF15206.6 GAX10240.1 - 0.084 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 FAM209 family DUF1499 PF07386.11 GAX10241.1 - 8.1e-10 39.3 0.6 1.8e-09 38.2 0.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1499) DUF1499 PF07386.11 GAX10242.1 - 6.2e-08 33.2 0.7 1.1e-07 32.4 0.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1499) ABC1 PF03109.16 GAX10243.1 - 2.1e-25 89.2 0.0 3.9e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GAX10243.1 - 0.015 14.7 0.0 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain DUF5325 PF17259.2 GAX10247.1 - 0.0014 18.5 3.5 0.0057 16.5 0.7 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5325) PhyH PF05721.13 GAX10248.1 - 9e-09 35.9 0.4 1e-06 29.2 0.3 2.4 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) ArfGap PF01412.18 GAX10249.1 - 6.9e-23 80.9 0.5 1.6e-22 79.7 0.5 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SNAP PF14938.6 GAX10250.1 - 2e-11 43.9 21.4 5.4e-09 35.9 4.2 2.4 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Histone PF00125.24 GAX10250.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.3 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 LEA_3 PF03242.13 GAX10250.1 - 9.6 7.0 11.2 1.1 10.1 4.9 2.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein AOX PF01786.17 GAX10251.1 - 5e-27 94.9 0.4 6.4e-27 94.6 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 GAX10251.1 - 0.072 12.9 0.1 0.27 11.0 0.1 1.9 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Ank_2 PF12796.7 GAX10252.1 - 9.4e-25 87.0 0.3 8.1e-12 45.6 0.0 3.1 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Pkinase PF00069.25 GAX10252.1 - 7.9e-23 81.2 0.5 4.3e-16 59.1 0.3 2.4 1 1 1 2 2 2 2 Protein kinase domain Ank_4 PF13637.6 GAX10252.1 - 2.3e-20 72.7 0.3 3.2e-08 33.9 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 GAX10252.1 - 6.1e-19 68.3 0.6 3.1e-17 62.7 0.6 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 GAX10252.1 - 4.8e-15 55.4 0.2 3.9e-06 27.0 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX10252.1 - 1.9e-14 53.3 0.4 1.5e-05 25.2 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 GAX10252.1 - 8e-13 47.3 0.1 0.00025 21.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat DEAD PF00270.29 GAX10253.1 - 1.9e-23 83.1 0.1 5.4e-22 78.4 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX10253.1 - 4.7e-14 52.7 0.0 1.9e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX10253.1 - 1.8e-06 28.1 0.0 8.9e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit VASt PF16016.5 GAX10254.1 - 1.1e-11 45.4 0.0 2.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GIDA PF01134.22 GAX10254.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_A22B PF04258.13 GAX10255.1 - 1.6e-82 277.2 3.5 2.8e-82 276.5 3.5 1.3 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 GAX10255.1 - 0.00047 19.7 2.4 0.00047 19.7 2.4 3.1 2 1 1 3 3 3 1 Signal-peptide peptidase, presenilin aspartyl protease FA_desaturase PF00487.24 GAX10255.1 - 0.63 9.8 0.0 0.63 9.8 0.0 2.8 2 1 1 4 4 4 0 Fatty acid desaturase Myb_DNA-binding PF00249.31 GAX10256.1 - 3.1e-26 91.3 6.9 1.7e-12 47.3 0.2 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX10256.1 - 4.1e-22 78.2 4.9 8.3e-12 45.2 0.5 3.8 2 2 1 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAX10256.1 - 0.00046 20.3 1.0 0.01 16.0 0.1 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 IRF PF00605.17 GAX10256.1 - 0.016 15.5 1.6 0.032 14.5 0.1 2.2 1 1 1 2 2 2 0 Interferon regulatory factor transcription factor RHH_4 PF13467.6 GAX10256.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain Tn7_Tnp_TnsA_C PF08721.11 GAX10256.1 - 0.07 13.8 0.0 2.6 8.7 0.0 2.7 3 0 0 3 3 3 0 TnsA endonuclease C terminal Prominin PF05478.11 GAX10256.1 - 0.072 11.0 0.1 0.087 10.8 0.1 1.0 1 0 0 1 1 1 0 Prominin Myb_DNA-bind_7 PF15963.5 GAX10256.1 - 0.19 11.7 4.5 0.83 9.6 1.1 3.1 2 1 0 2 2 2 0 Myb DNA-binding like Get5_C PF18514.1 GAX10257.1 - 0.07 12.9 1.0 0.73 9.6 0.1 2.8 3 0 0 3 3 3 0 Get5 C-terminal domain DUF1456 PF07308.13 GAX10257.1 - 0.37 11.1 1.8 9.2 6.7 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1456) Methyltransf_4 PF02390.17 GAX10258.1 - 5.9e-30 104.0 0.0 4.6e-29 101.1 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 GAX10258.1 - 0.0027 18.4 0.0 0.27 12.0 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX10258.1 - 0.0043 17.7 0.1 2.9 8.6 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain N6_N4_Mtase PF01555.18 GAX10258.1 - 0.0092 15.7 0.2 0.092 12.4 0.0 2.1 1 1 1 2 2 2 1 DNA methylase BCL9 PF11502.8 GAX10258.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Methyltransf_23 PF13489.6 GAX10258.1 - 0.084 12.7 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10258.1 - 0.18 12.6 0.0 11 6.8 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain 2OG-FeII_Oxy_3 PF13640.6 GAX10259.1 - 2.2e-13 50.9 0.1 6.9e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily VHL PF01847.16 GAX10259.1 - 0.091 12.7 0.0 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 VHL beta domain UspB PF10625.9 GAX10259.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein B (UspB) Cyclin_N PF00134.23 GAX10260.1 - 3.2e-09 36.6 1.0 7.9e-09 35.3 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAX10260.1 - 7.9e-06 26.3 0.9 1.4e-05 25.5 0.1 1.8 2 0 0 2 2 2 1 Cyclin WW PF00397.26 GAX10260.1 - 2e-05 24.6 2.0 2e-05 24.6 2.0 2.4 2 0 0 2 2 2 1 WW domain WD40 PF00400.32 GAX10261.1 - 3.4e-09 37.2 7.3 1.2 10.1 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX10261.1 - 1e-06 28.9 0.0 0.18 12.1 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L10 PF00466.20 GAX10262.1 - 6e-20 71.3 0.2 1.1e-19 70.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 Ank_2 PF12796.7 GAX10263.1 - 1.3e-32 112.2 1.4 1.8e-14 54.1 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAX10263.1 - 5.2e-24 83.6 18.2 7.4e-07 29.3 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 GAX10263.1 - 5.2e-22 75.6 9.7 8.4e-05 22.7 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 GAX10263.1 - 9e-21 74.0 7.6 5.9e-10 39.5 0.1 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX10263.1 - 2.8e-20 72.1 16.6 1.3e-05 25.3 0.1 6.9 4 3 4 8 8 8 4 Ankyrin repeats (many copies) DUF179 PF02622.15 GAX10264.1 - 4.5e-31 108.0 0.0 7.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Auts2 PF15336.6 GAX10265.1 - 0.036 14.2 0.3 0.036 14.2 0.3 2.2 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Dynein_C PF18199.1 GAX10265.1 - 0.6 9.3 11.2 0.22 10.7 8.6 1.6 1 1 0 1 1 1 0 Dynein heavy chain C-terminal domain CRT10 PF08728.10 GAX10265.1 - 2.3 6.3 10.6 2.9 6.0 10.6 1.1 1 0 0 1 1 1 0 CRT10 MTP18 PF10558.9 GAX10265.1 - 6.8 6.6 7.0 0.52 10.3 0.9 2.1 1 1 1 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) Pkinase PF00069.25 GAX10266.1 - 2e-49 168.3 0.0 2.4e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10266.1 - 7.4e-29 100.8 0.0 9.5e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX10266.1 - 6.3e-05 23.0 0.2 0.00044 20.2 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX10266.1 - 0.0001 21.9 0.0 0.002 17.8 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 GAX10266.1 - 0.003 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX10266.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 GAX10266.1 - 0.028 14.0 0.0 0.072 12.7 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 GAX10266.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Methyltransf_25 PF13649.6 GAX10268.1 - 2.8e-06 27.9 0.0 1.4e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX10268.1 - 2.7e-05 24.1 0.0 0.00012 22.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX10268.1 - 0.0029 18.2 0.1 0.0091 16.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10268.1 - 0.0065 17.2 0.0 0.034 14.9 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain zf_CCCH_4 PF18345.1 GAX10268.1 - 0.015 15.4 4.5 0.04 14.0 4.5 1.8 1 0 0 1 1 1 0 Zinc finger domain PUFD PF16553.5 GAX10268.1 - 0.037 14.2 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain zf-CCCH PF00642.24 GAX10268.1 - 0.052 13.5 4.1 0.12 12.3 4.1 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2855 PF11017.8 GAX10268.1 - 0.11 12.2 0.4 0.18 11.5 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2855) Methyltransf_31 PF13847.6 GAX10268.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-CCCH_2 PF14608.6 GAX10268.1 - 0.43 11.1 6.8 0.93 10.1 6.8 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Methyltr_RsmB-F PF01189.17 GAX10269.1 - 5e-40 137.3 0.0 5.8e-38 130.5 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GAX10269.1 - 0.0023 18.1 0.1 0.0044 17.1 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 GAX10269.1 - 0.12 13.0 0.0 0.35 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF4147 PF13660.6 GAX10270.1 - 1.7e-74 250.2 0.1 2.3e-74 249.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 GAX10270.1 - 6.8e-18 64.9 0.6 2.4e-17 63.1 0.2 2.2 3 0 0 3 3 3 1 MOFRL family DUF267 PF03268.14 GAX10270.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 Uso1_p115_head PF04869.14 GAX10271.1 - 0.022 13.9 0.5 0.059 12.5 0.1 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region Dimer_Tnp_hAT PF05699.14 GAX10271.1 - 0.03 14.1 0.4 1.3 8.9 0.1 2.8 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Arm PF00514.23 GAX10271.1 - 0.075 13.1 8.5 6.8 6.9 0.4 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat tRNA-synt_1 PF00133.22 GAX10272.1 - 1.1e-69 235.3 1.9 4.2e-45 154.1 0.1 3.8 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 GAX10272.1 - 5e-69 231.5 0.0 8.2e-69 230.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 GAX10272.1 - 3.8e-26 91.8 0.0 2.9e-17 62.5 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAX10272.1 - 1.6e-15 57.4 0.1 6.5e-15 55.4 0.1 1.9 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GAX10272.1 - 1e-05 25.1 0.0 0.0064 15.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 GAX10272.1 - 0.017 14.1 0.0 0.23 10.3 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.25 GAX10272.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 GAX10272.1 - 0.082 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Peptidase_C14 PF00656.22 GAX10273.1 - 3.8e-45 154.8 1.4 8.5e-36 124.2 0.5 2.0 2 0 0 2 2 2 2 Caspase domain Raptor_N PF14538.6 GAX10273.1 - 0.26 11.2 1.5 2.3 8.2 0.7 2.4 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Corona_M PF01635.18 GAX10274.1 - 0.013 14.8 0.4 0.021 14.2 0.4 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein S6OS1 PF15676.5 GAX10275.1 - 0.0061 15.1 6.4 0.008 14.7 6.4 1.2 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family TPP_enzyme_N PF02776.18 GAX10275.1 - 0.082 12.5 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MCD_N PF17408.2 GAX10275.1 - 0.17 12.0 1.5 0.37 10.9 1.3 1.7 1 1 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain eIF3_N PF09440.10 GAX10275.1 - 0.55 10.7 6.8 0.99 9.8 6.8 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain DAO PF01266.24 GAX10277.1 - 6.4e-40 137.8 0.0 1.1e-39 137.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 GAX10277.1 - 2.7e-35 121.0 0.1 7.4e-35 119.6 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 GAX10277.1 - 3e-11 43.1 0.4 9.8e-11 41.4 0.4 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAX10277.1 - 0.0004 19.7 0.1 0.0056 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX10277.1 - 0.0017 18.9 1.1 0.38 11.3 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX10277.1 - 0.0043 16.3 0.4 0.2 10.9 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain DUF433 PF04255.14 GAX10277.1 - 0.0049 16.7 0.1 1.4 8.9 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF433) FAD_oxidored PF12831.7 GAX10277.1 - 0.006 16.0 0.2 0.015 14.7 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 GAX10277.1 - 0.036 13.4 1.3 0.062 12.7 0.0 1.9 2 1 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 GAX10277.1 - 0.038 13.3 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX10277.1 - 0.048 13.9 1.2 0.17 12.1 0.7 2.2 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 GAX10277.1 - 0.06 13.2 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 GAX10277.1 - 0.073 12.1 1.0 4.9 6.1 0.5 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Hydrolase_2 PF07486.12 GAX10277.1 - 0.084 13.7 0.0 2 9.3 0.0 2.7 2 0 0 2 2 2 0 Cell Wall Hydrolase K_oxygenase PF13434.6 GAX10277.1 - 0.094 11.8 0.2 0.99 8.5 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 GAX10277.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 GAX10277.1 - 0.19 10.4 0.3 0.31 9.7 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Carboxyl_trans PF01039.22 GAX10278.1 - 2.9e-152 507.8 0.0 4.1e-152 507.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 GAX10278.1 - 5.1e-125 418.4 0.0 6.3e-125 418.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 GAX10278.1 - 6e-51 173.0 0.1 1.4e-50 171.7 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAX10278.1 - 8.9e-25 87.4 0.0 2.4e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAX10278.1 - 1.8e-21 76.2 0.0 4.3e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAX10278.1 - 3.3e-11 42.8 0.0 1e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 GAX10278.1 - 0.00022 20.8 0.9 0.00076 19.1 0.1 2.2 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAX10278.1 - 0.0005 19.7 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAX10278.1 - 0.0014 18.7 0.0 0.0045 17.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Abhydrolase_5 PF12695.7 GAX10278.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family LAL_C2 PF18603.1 GAX10278.1 - 0.1 12.8 0.1 0.73 10.0 0.0 2.6 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 PIN_6 PF17146.4 GAX10279.1 - 2.8e-29 101.5 0.3 1.5e-28 99.1 0.0 2.4 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 GAX10279.1 - 9.1e-23 80.2 0.3 2.1e-22 79.1 0.3 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AAA PF00004.29 GAX10280.1 - 1.8e-32 112.5 0.0 6.3e-29 101.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX10280.1 - 5.8e-09 35.6 0.8 1.7e-08 34.1 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 GAX10280.1 - 5.1e-07 30.2 0.4 0.0036 17.7 0.0 3.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAX10280.1 - 1.1e-06 29.0 0.0 0.0018 18.6 0.0 4.3 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 GAX10280.1 - 8.7e-05 22.5 0.0 0.0056 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX10280.1 - 0.00046 19.6 0.3 0.0013 18.2 0.0 2.0 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAX10280.1 - 0.00084 19.7 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 GAX10280.1 - 0.00087 19.1 0.6 0.028 14.2 0.1 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 GAX10280.1 - 0.0023 17.9 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAX10280.1 - 0.0039 17.7 0.0 0.088 13.3 0.0 2.5 2 1 0 2 2 2 1 ABC transporter NACHT PF05729.12 GAX10280.1 - 0.0052 16.7 0.1 0.51 10.2 0.0 3.0 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 GAX10280.1 - 0.0052 16.5 0.1 0.016 14.9 0.1 1.9 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAX10280.1 - 0.0073 16.9 0.1 0.099 13.2 0.1 2.7 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 GAX10280.1 - 0.0084 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 GAX10280.1 - 0.014 15.0 1.3 0.75 9.3 0.0 3.8 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.6 GAX10280.1 - 0.02 15.1 0.8 1.1 9.4 0.0 3.2 4 0 0 4 4 2 0 AAA domain TIP49 PF06068.13 GAX10280.1 - 0.02 14.1 0.1 0.041 13.1 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 GAX10280.1 - 0.023 14.4 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAX10280.1 - 0.027 14.8 0.2 0.77 10.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 GAX10280.1 - 0.037 13.8 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 GAX10280.1 - 0.046 12.8 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 GAX10280.1 - 0.049 13.9 0.1 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX10280.1 - 0.049 13.1 0.1 0.48 9.9 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAX10280.1 - 0.06 13.1 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAX10280.1 - 0.088 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 GAX10280.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 GAX10280.1 - 0.1 12.6 0.0 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAX10280.1 - 0.17 11.1 0.1 5.9 6.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 GAX10280.1 - 0.21 11.5 0.0 5.3 6.9 0.0 2.6 2 0 0 2 2 2 0 NTPase Pyr_redox_2 PF07992.14 GAX10281.1 - 6e-53 180.0 0.1 7.8e-53 179.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX10281.1 - 2.1e-14 53.7 0.0 3.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX10281.1 - 2.5e-13 50.4 4.3 3.6e-12 46.7 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX10281.1 - 9.2e-06 25.1 0.0 6.6e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 GAX10281.1 - 3.8e-05 24.2 0.0 0.00013 22.4 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain NAD_binding_8 PF13450.6 GAX10281.1 - 0.00012 22.2 0.2 0.052 13.8 0.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 GAX10281.1 - 0.013 15.9 0.1 0.59 10.6 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAX10281.1 - 0.085 11.9 1.0 2.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 GAX10281.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAX10281.1 - 0.19 11.7 4.6 2.9 7.9 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding PI-PLC-X PF00388.19 GAX10282.1 - 9.8e-47 158.2 0.0 2.1e-46 157.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAX10282.1 - 6.8e-38 129.5 0.2 1.6e-37 128.3 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 GAX10282.1 - 1.1e-12 48.1 0.0 2.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain EPSP_synthase PF00275.20 GAX10282.1 - 0.029 13.0 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Laminin_G_3 PF13385.6 GAX10283.1 - 2.3e-05 24.6 0.0 7.6e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TPR_2 PF07719.17 GAX10285.1 - 1.2e-21 75.0 16.8 0.00022 21.1 0.1 8.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10285.1 - 2.5e-17 61.5 2.9 0.0092 16.1 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10285.1 - 6.3e-17 60.6 4.9 0.00014 21.5 0.1 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX10285.1 - 8.7e-11 41.7 20.8 2.3 9.2 0.9 9.6 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX10285.1 - 1e-07 32.2 15.0 0.00092 19.5 2.2 6.0 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10285.1 - 1.6e-07 31.8 8.2 0.015 16.0 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX10285.1 - 1.7e-07 30.8 8.6 0.081 13.0 0.1 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10285.1 - 4.6e-07 29.4 5.1 0.24 11.1 0.0 6.0 6 1 1 7 7 7 2 TPR repeat TPR_10 PF13374.6 GAX10285.1 - 1.2e-06 28.2 7.9 0.12 12.3 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX10285.1 - 3.2e-05 24.0 1.3 36 5.1 0.1 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX10285.1 - 4e-05 24.1 5.5 4.4 7.9 0.0 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10285.1 - 0.00037 20.6 6.9 5.7 7.2 0.6 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX10285.1 - 0.01 16.1 0.4 0.01 16.1 0.4 5.3 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 GAX10285.1 - 0.12 11.8 1.8 0.81 9.1 0.4 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 GAX10285.1 - 0.14 12.9 6.1 24 5.8 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat RINGv PF12906.7 GAX10286.1 - 1.8e-06 28.0 4.0 1.8e-06 28.0 4.0 3.0 3 0 0 3 3 3 1 RING-variant domain zf-MYND PF01753.18 GAX10286.1 - 3.7e-05 23.7 16.6 3.7e-05 23.7 16.6 2.3 2 0 0 2 2 2 1 MYND finger SurA_N_3 PF13624.6 GAX10286.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain NmrA PF05368.13 GAX10288.1 - 4.8e-23 81.9 0.0 6.3e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAX10288.1 - 3.1e-10 40.3 0.0 5.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAX10288.1 - 0.00039 20.7 0.1 0.061 13.6 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 GAX10288.1 - 0.00081 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 GAX10288.1 - 0.054 13.5 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 GAX10288.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Tim17 PF02466.19 GAX10289.1 - 4.6e-13 49.5 1.5 8.7e-13 48.6 1.5 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family JHD PF17811.1 GAX10290.1 - 7e-09 36.2 0.0 1.7e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 GAX10290.1 - 3e-08 34.1 0.1 2.5e-07 31.1 0.0 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GAX10290.1 - 4.1e-06 26.7 0.1 1.1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 Cupin-like domain DUF4612 PF15389.6 GAX10290.1 - 0.082 14.0 0.1 6.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) DENN PF02141.21 GAX10291.1 - 2.1e-26 93.0 3.3 2e-25 89.9 3.3 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain NmrA PF05368.13 GAX10291.1 - 1.1e-12 48.1 0.3 1.3e-06 28.2 0.4 2.5 1 1 1 2 2 2 2 NmrA-like family ENTH PF01417.20 GAX10291.1 - 1.8e-11 44.2 0.0 3.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain NAD_binding_10 PF13460.6 GAX10291.1 - 2.1e-09 37.5 0.1 4.6e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding dDENN PF03455.19 GAX10291.1 - 0.003 17.5 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 dDENN domain Sacchrp_dh_NADP PF03435.18 GAX10291.1 - 0.0052 17.0 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain PUB PF09409.10 GAX10292.1 - 1.8e-12 47.0 0.0 4.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 PUB domain SPACA9 PF15120.6 GAX10292.1 - 0.0043 16.9 5.3 0.0074 16.1 5.3 1.3 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 dCache_1 PF02743.18 GAX10292.1 - 0.028 14.2 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 Cache domain DUF4404 PF14357.6 GAX10292.1 - 0.038 14.6 0.9 0.038 14.6 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1539 PF07560.11 GAX10292.1 - 0.25 11.4 2.5 0.6 10.2 2.5 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Peptidase_S64 PF08192.11 GAX10292.1 - 0.27 9.7 2.7 0.39 9.2 2.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Phage_GPO PF05929.11 GAX10292.1 - 0.45 10.1 3.1 0.69 9.5 3.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MLD PF11647.8 GAX10292.1 - 0.65 10.3 2.3 1.2 9.5 0.2 2.3 2 0 0 2 2 2 0 Membrane Localization Domain CENP-Q PF13094.6 GAX10292.1 - 3.4 7.8 12.2 2.1 8.5 8.4 2.5 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit CRCB PF02537.15 GAX10293.1 - 2.9e-20 72.4 10.8 4.3e-10 39.8 4.7 3.3 3 0 0 3 3 3 3 CrcB-like protein, Camphor Resistance (CrcB) GDPD_2 PF13653.6 GAX10293.1 - 0.14 12.6 0.2 10 6.8 0.1 2.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family ArfGap PF01412.18 GAX10294.1 - 1.3e-32 112.3 0.0 2.8e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 GAX10294.1 - 1.9e-13 50.8 0.0 3.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 PH domain BAR_3 PF16746.5 GAX10294.1 - 3.6e-11 43.3 0.2 1.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 BAR domain of APPL family SBP PF03110.14 GAX10294.1 - 0.041 14.2 0.1 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 SBP domain Ank_4 PF13637.6 GAX10294.1 - 0.085 13.5 0.2 2.5 8.8 0.2 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) HBM PF16591.5 GAX10296.1 - 0.025 14.0 1.4 0.084 12.3 0.1 1.9 1 1 1 2 2 2 0 Helical bimodular sensor domain SRP54_N PF02881.19 GAX10296.1 - 0.042 14.1 1.5 0.27 11.5 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Spc7 PF08317.11 GAX10296.1 - 0.063 12.2 8.9 0.31 9.9 8.9 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 GAX10296.1 - 0.11 12.6 4.3 0.12 12.4 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1666 PF07891.12 GAX10296.1 - 0.13 11.9 0.5 0.2 11.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) DUF2564 PF10819.8 GAX10296.1 - 0.16 12.4 0.3 0.16 12.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) DUF948 PF06103.11 GAX10296.1 - 0.17 12.2 5.2 0.9 9.8 4.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 GAX10296.1 - 0.2 11.7 1.9 0.3 11.1 1.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 GAX10296.1 - 0.27 10.5 2.2 0.19 10.9 0.7 1.4 1 1 0 1 1 1 0 TMPIT-like protein IZUMO PF15005.6 GAX10296.1 - 0.53 10.8 2.4 0.36 11.4 0.6 1.5 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF724 PF05266.14 GAX10296.1 - 0.55 10.0 4.3 0.67 9.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 GAX10296.1 - 0.62 8.6 8.6 0.036 12.7 1.6 1.8 1 1 1 2 2 2 0 AAA domain DUF2959 PF11172.8 GAX10296.1 - 0.72 10.0 6.2 1.5 9.0 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2959) YvbH_ext PF11724.8 GAX10296.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.1 2 1 1 3 3 3 0 YvbH-like oligomerisation region Laminin_II PF06009.12 GAX10296.1 - 1.4 8.9 8.5 16 5.5 5.6 2.7 1 1 1 2 2 2 0 Laminin Domain II APG6_N PF17675.1 GAX10296.1 - 2.9 8.4 10.8 24 5.4 11.0 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region BRE1 PF08647.11 GAX10296.1 - 2.9 8.0 9.8 0.57 10.3 1.7 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 GAX10296.1 - 3.5 7.7 14.2 0.29 11.1 3.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SH3_12 PF18129.1 GAX10297.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.6 1 1 0 1 1 1 0 Xrn1 SH3-like domain Lycopene_cycl PF05834.12 GAX10298.1 - 1.7e-59 201.8 0.0 1.5e-58 198.7 0.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAX10298.1 - 0.099 11.9 0.0 9.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Mito_carr PF00153.27 GAX10299.1 - 4.2e-66 218.9 0.4 4.3e-23 81.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX10299.1 - 0.0009 18.5 0.4 9.3 5.3 0.0 3.9 3 1 1 4 4 4 2 Gammaproteobacterial serine protease Zip PF02535.22 GAX10299.1 - 0.0031 16.8 9.2 0.005 16.1 9.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Hydin_ADK PF17213.3 GAX10299.1 - 0.43 10.8 3.4 0.16 12.2 0.8 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NicO PF03824.16 GAX10299.1 - 0.67 9.2 10.7 1.6 8.0 10.1 1.8 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF2868 PF11067.8 GAX10299.1 - 1.9 8.0 4.5 1.1 8.6 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Macoilin PF09726.9 GAX10299.1 - 8.8 4.8 10.8 13 4.2 10.8 1.1 1 0 0 1 1 1 0 Macoilin family Met_10 PF02475.16 GAX10300.1 - 1.3e-25 90.4 0.0 1.9e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 GAX10300.1 - 5.3e-06 26.1 0.0 9.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX10300.1 - 9.9e-06 26.2 0.0 1.9e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX10300.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 GAX10300.1 - 0.0003 20.3 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAX10300.1 - 0.0019 18.0 0.0 0.0047 16.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX10300.1 - 0.0093 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 GAX10300.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.20 GAX10300.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DNA_methylase PF00145.17 GAX10300.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF604 PF04646.12 GAX10300.1 - 0.1 12.0 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 DUF3598 PF12204.8 GAX10301.1 - 9.9e-08 31.8 0.4 1.1e-05 25.1 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3598) Ca_hom_mod PF14798.6 GAX10301.1 - 0.24 10.5 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator PhoLip_ATPase_C PF16212.5 GAX10302.1 - 9.6e-50 169.7 8.8 9.6e-50 169.7 8.8 2.2 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAX10302.1 - 1.1e-13 50.6 0.1 1.1e-13 50.6 0.1 3.2 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAX10302.1 - 2.3e-10 41.1 0.3 0.0002 21.7 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX10302.1 - 3.3e-05 23.9 0.0 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAX10302.1 - 7.2e-05 22.4 0.3 0.01 15.4 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAX10302.1 - 0.029 14.1 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MSA_2 PF00985.17 GAX10304.1 - 9.9 6.5 13.5 12 6.2 13.5 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family FoP_duplication PF13865.6 GAX10305.1 - 1.9e-13 50.8 17.2 1.9e-13 50.8 17.2 2.2 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Tho2 PF11262.8 GAX10305.1 - 7.3 5.7 10.3 8.1 5.5 10.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GalKase_gal_bdg PF10509.9 GAX10306.1 - 1.6e-19 69.1 0.7 3.6e-19 68.1 0.2 1.8 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 GAX10306.1 - 6.1e-14 52.2 0.2 6.1e-13 49.0 0.0 2.5 3 0 0 3 3 3 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAX10306.1 - 1e-09 38.4 0.5 3e-09 37.0 0.4 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain Ntox34 PF15606.6 GAX10306.1 - 0.089 12.9 0.7 3.7 7.7 0.1 3.0 2 1 1 3 3 3 0 Bacterial toxin 34 Fumble PF03630.14 GAX10306.1 - 0.099 11.8 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Fumble PP2C PF00481.21 GAX10307.1 - 5.6e-45 154.0 0.3 7.2e-45 153.6 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX10307.1 - 3e-08 33.6 0.1 6.1e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Kinesin PF00225.23 GAX10308.1 - 7.8e-100 334.0 0.1 2.5e-99 332.3 0.1 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX10308.1 - 2.1e-25 89.4 0.0 9.8e-25 87.2 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding DUF3067 PF11267.8 GAX10308.1 - 0.046 14.3 0.1 2.9 8.5 0.1 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) PLAC9 PF15205.6 GAX10308.1 - 1.9 9.0 4.6 36 4.9 0.6 4.0 3 0 0 3 3 3 0 Placenta-specific protein 9 Phytochelatin PF05023.14 GAX10310.1 - 2.9e-79 265.2 0.0 3.4e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase LRR_6 PF13516.6 GAX10311.1 - 4.8e-15 54.2 5.0 0.11 12.7 0.0 7.3 7 0 0 7 7 7 6 Leucine Rich repeat LRR_8 PF13855.6 GAX10311.1 - 0.034 13.9 4.8 3.4 7.5 0.2 4.6 4 1 1 5 5 5 0 Leucine rich repeat ROK PF00480.20 GAX10312.1 - 8.1e-40 137.1 0.0 9.6e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 GAX10312.1 - 0.01 14.9 1.4 0.052 12.5 0.8 2.1 2 0 0 2 2 2 0 Glucokinase baeRF_family10 PF18854.1 GAX10312.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Creb_binding PF09030.10 GAX10312.1 - 0.051 14.3 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Creb binding Polyketide_cyc PF03364.20 GAX10313.1 - 2.4e-08 34.2 0.4 1.9e-07 31.4 0.4 2.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAX10313.1 - 0.001 19.4 0.0 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport BAR PF03114.18 GAX10313.1 - 0.013 15.1 3.1 0.11 12.1 0.6 2.3 1 1 0 2 2 2 0 BAR domain Med24_N PF11277.8 GAX10313.1 - 0.14 10.2 4.1 0.21 9.6 4.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal NAD_binding_2 PF03446.15 GAX10313.1 - 0.22 11.7 2.7 0.71 10.0 0.1 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Syntaxin-6_N PF09177.11 GAX10313.1 - 1.3 9.6 5.3 0.95 10.1 2.1 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Metal_resist PF13801.6 GAX10313.1 - 1.5 9.0 11.2 0.19 11.9 0.2 3.0 1 1 1 2 2 2 0 Heavy-metal resistance 2OG-FeII_Oxy_3 PF13640.6 GAX10314.1 - 9.3e-10 39.3 0.0 2.5e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RVT_thumb PF06817.14 GAX10314.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Cofac_haem_bdg PF04187.13 GAX10315.1 - 1.8e-12 47.7 0.0 4.8e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Haem-binding uptake, Tiki superfamily, ChaN zf-CCHC PF00098.23 GAX10316.1 - 6.1e-15 54.5 28.6 6.7e-06 25.9 0.6 4.7 5 0 0 5 5 5 4 Zinc knuckle RRM_1 PF00076.22 GAX10316.1 - 5.2e-11 42.2 0.0 9.2e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.6 GAX10316.1 - 6e-05 22.7 24.0 0.089 12.5 0.9 4.6 5 0 0 5 5 5 3 Zinc knuckle Mu-like_Com PF10122.9 GAX10316.1 - 0.02 14.3 1.7 0.1 12.1 0.2 2.9 1 1 1 2 2 2 0 Mu-like prophage protein Com HypA PF01155.19 GAX10316.1 - 4.6 7.3 11.3 1.8 8.6 1.4 3.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_3 PF13917.6 GAX10316.1 - 4.6 7.3 21.8 5.7 7.0 0.1 4.7 4 1 1 5 5 5 0 Zinc knuckle zf-CCHC_5 PF14787.6 GAX10316.1 - 5.2 6.9 18.2 2.3 8.0 0.2 4.5 4 1 1 5 5 5 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GAX10316.1 - 9.5 6.2 33.2 1.4 8.8 1.8 4.8 5 0 0 5 5 5 0 Zinc knuckle Abhydrolase_3 PF07859.13 GAX10317.1 - 0.002 18.0 0.0 0.0045 16.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX10317.1 - 0.0025 17.1 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAX10317.1 - 0.035 13.9 0.1 0.059 13.2 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 GAX10317.1 - 0.083 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase RPE65 PF03055.15 GAX10318.1 - 3.6e-101 339.7 0.1 4.4e-101 339.4 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FAD_binding_1 PF00667.20 GAX10319.1 - 1.5e-50 171.9 0.0 2.5e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX10319.1 - 1.1e-24 87.3 0.1 2.4e-24 86.2 0.1 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GAX10319.1 - 4.4e-18 65.9 0.1 1.1e-17 64.6 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAX10319.1 - 0.077 13.1 0.0 1.8 8.7 0.0 2.4 1 1 1 2 2 2 0 Ferric reductase NAD binding domain FAD_binding_3 PF01494.19 GAX10320.1 - 4.5e-14 52.5 1.2 4.9e-07 29.3 0.3 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX10320.1 - 7.9e-05 22.4 2.6 0.12 11.9 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAX10320.1 - 0.00036 19.9 0.1 0.00088 18.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAX10320.1 - 0.00039 19.7 0.3 0.00063 19.1 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX10320.1 - 0.0011 17.9 0.2 0.96 8.2 0.0 2.5 2 1 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 GAX10320.1 - 0.0013 18.2 0.1 0.0023 17.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX10320.1 - 0.0016 18.5 0.1 3.6 7.6 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAX10320.1 - 0.0077 16.4 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAX10320.1 - 0.02 14.0 0.2 0.03 13.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 GAX10320.1 - 0.025 13.3 0.1 0.039 12.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 GAX10320.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAX10320.1 - 0.12 13.0 0.1 0.34 11.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2358 PF10184.9 GAX10321.1 - 3.5e-09 36.9 0.0 4.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 GAX10321.1 - 0.052 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain FlgT_M PF16539.5 GAX10321.1 - 0.069 13.3 0.1 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Flagellar assembly protein T, middle domain HA PF03457.14 GAX10322.1 - 1.1e-58 195.5 11.8 1.8e-16 60.2 0.5 4.3 4 0 0 4 4 4 4 Helicase associated domain TUDOR_5 PF18359.1 GAX10322.1 - 0.032 13.9 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 HA PF03457.14 GAX10323.1 - 2.2e-57 191.2 27.1 1.5e-17 63.6 0.2 4.8 5 0 0 5 5 5 4 Helicase associated domain TUDOR_5 PF18359.1 GAX10323.1 - 0.075 12.8 3.8 6.7 6.5 0.5 2.8 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 T3SS_ATPase_C PF18269.1 GAX10324.1 - 0.018 14.8 0.6 0.039 13.8 0.6 1.5 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain BRE1 PF08647.11 GAX10324.1 - 0.036 14.1 3.2 0.1 12.7 3.2 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF572 PF04502.13 GAX10324.1 - 0.074 12.7 1.4 0.7 9.5 1.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) APG6_N PF17675.1 GAX10324.1 - 2.5 8.6 8.0 0.28 11.7 2.3 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region PMSR PF01625.21 GAX10325.1 - 6.2e-48 162.9 0.1 7.2e-48 162.6 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ist1 PF03398.14 GAX10325.1 - 0.029 14.3 0.1 0.04 13.9 0.1 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF5117 PF17148.4 GAX10325.1 - 0.052 13.4 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5117) IPP-2 PF04979.14 GAX10326.1 - 9.4e-22 78.2 12.4 9.4e-22 78.2 12.4 1.6 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3787 PF12655.7 GAX10329.1 - 0.15 12.0 1.2 1.1 9.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3787) RRP36 PF06102.12 GAX10330.1 - 0.16 11.9 0.3 0.28 11.1 0.3 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 UCH PF00443.29 GAX10331.1 - 7.9e-62 209.1 0.1 1.4e-61 208.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX10331.1 - 1.1e-06 28.5 2.0 0.00067 19.3 0.1 3.7 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAX10331.1 - 0.003 18.2 0.0 0.016 15.8 0.0 2.4 1 1 0 1 1 1 1 DUSP domain HipN PF18253.1 GAX10331.1 - 0.17 11.6 0.1 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Peptidase_M24 PF00557.24 GAX10332.1 - 5.5e-39 134.0 0.0 6.8e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.14 GAX10332.1 - 0.91 7.7 5.6 1.1 7.4 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.14 GAX10332.1 - 6.5 5.3 14.3 10 4.6 14.3 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 LETM1 PF07766.13 GAX10333.1 - 2.3e-92 309.1 6.7 2.3e-92 309.1 6.7 2.7 2 1 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 GAX10333.1 - 3.6e-09 36.9 0.6 1.5e-08 35.0 0.6 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX10333.1 - 3.1e-05 23.5 0.8 0.036 14.0 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 GAX10333.1 - 6.1e-05 22.3 0.2 0.059 13.0 0.0 2.9 2 0 0 2 2 2 2 EF hand SUIM_assoc PF16619.5 GAX10333.1 - 0.0011 19.0 1.7 0.0011 19.0 1.7 4.1 5 0 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 EF-hand_5 PF13202.6 GAX10333.1 - 0.0077 15.7 2.7 0.049 13.1 0.2 3.1 3 0 0 3 3 3 1 EF hand SAP PF02037.27 GAX10333.1 - 0.0098 15.6 0.1 0.039 13.7 0.1 2.1 1 0 0 1 1 1 1 SAP domain EF-hand_8 PF13833.6 GAX10333.1 - 0.024 14.5 0.7 0.25 11.2 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAX10333.1 - 2.5 8.5 9.7 0.09 13.1 0.4 3.2 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region GTP_CH_N PF12471.8 GAX10334.1 - 1.8e-77 259.5 0.0 2.6e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 GAX10334.1 - 2.4e-14 53.3 0.0 3.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Chloroa_b-bind PF00504.21 GAX10335.1 - 2.2e-09 38.0 0.5 3.8e-05 24.3 0.1 2.1 1 1 0 2 2 2 2 Chlorophyll A-B binding protein Peptidase_M50 PF02163.22 GAX10336.1 - 0.14 11.4 1.5 1.4 8.1 1.5 2.3 1 1 0 1 1 1 0 Peptidase family M50 Ctr PF04145.15 GAX10337.1 - 1.3e-15 58.3 16.7 4.4e-08 33.9 10.1 2.5 1 1 1 2 2 2 2 Ctr copper transporter family C2 PF00168.30 GAX10338.1 - 1.7e-11 44.3 0.0 4.5e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 C2 domain SecA_DEAD PF07517.14 GAX10339.1 - 4.4e-111 370.8 0.4 9.8e-111 369.7 0.4 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 GAX10339.1 - 1e-41 143.2 4.5 1e-41 143.2 4.5 1.9 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 GAX10339.1 - 5.5e-27 94.6 0.0 1.9e-26 92.9 0.0 2.0 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 GAX10339.1 - 1.6e-05 24.7 0.0 4.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1664 PF07889.12 GAX10339.1 - 0.11 12.5 2.4 0.17 11.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 GAX10339.1 - 9.9 6.5 9.2 2 8.8 0.8 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 eIF-6 PF01912.18 GAX10340.1 - 2.1e-76 255.7 0.5 3.5e-76 255.0 0.4 1.4 2 0 0 2 2 2 1 eIF-6 family HA PF03457.14 GAX10341.1 - 3.6e-45 152.1 11.0 8.1e-17 61.3 0.3 4.2 4 0 0 4 4 4 3 Helicase associated domain DUF4936 PF16290.5 GAX10341.1 - 0.002 18.8 3.8 0.18 12.5 0.1 3.9 1 1 3 4 4 4 1 Domain of unknown function (DUF4936) DCP1 PF06058.13 GAX10341.1 - 0.052 13.5 1.4 0.19 11.7 0.0 2.6 4 0 0 4 4 4 0 Dcp1-like decapping family Ndc1_Nup PF09531.10 GAX10343.1 - 6.6 5.3 6.4 8 5.0 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NAD_binding_10 PF13460.6 GAX10344.1 - 2.3e-42 145.0 0.4 3.6e-42 144.3 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX10344.1 - 2.2e-10 40.5 0.4 4.1e-10 39.6 0.4 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAX10344.1 - 4.4e-09 36.2 0.1 9.7e-09 35.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX10344.1 - 7.7e-05 21.8 0.2 0.00011 21.3 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAX10344.1 - 0.00079 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase MecA_N PF05223.11 GAX10344.1 - 0.071 13.4 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain PSCyt3 PF07627.11 GAX10345.1 - 0.2 12.0 1.8 0.31 11.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) OmpH PF03938.14 GAX10345.1 - 0.85 10.0 38.2 3.2 8.1 2.1 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 GAX10345.1 - 2.2 8.3 27.7 0.17 11.9 1.4 3.5 2 1 1 3 3 3 0 Laminin Domain II ABC_tran_CTD PF16326.5 GAX10345.1 - 3.6 7.9 29.7 2.1 8.6 1.3 4.9 3 2 1 4 4 4 0 ABC transporter C-terminal domain Noelin-1 PF12308.8 GAX10345.1 - 4.6 7.3 17.0 0.54 10.3 0.3 3.7 3 0 0 3 3 3 0 Neurogenesis glycoprotein MAPKK1_Int PF08923.10 GAX10346.1 - 5.4e-08 32.7 0.0 6.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting LSM PF01423.22 GAX10347.1 - 2.3e-15 56.0 0.2 2.9e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX10347.1 - 9.1e-05 22.5 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2715 PF10895.8 GAX10347.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) CDP-OH_P_transf PF01066.21 GAX10348.1 - 2.4e-14 53.9 0.6 2.4e-14 53.9 0.6 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4267 PF14087.6 GAX10348.1 - 0.14 12.2 3.1 0.46 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) Syja_N PF02383.18 GAX10350.1 - 4.6e-72 243.0 0.0 9e-72 242.1 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain ZipA_C PF04354.13 GAX10350.1 - 0.091 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain FEZ PF07763.13 GAX10351.1 - 0.017 14.8 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 FEZ-like protein Chloroa_b-bind PF00504.21 GAX10353.1 - 8e-29 101.2 0.1 1.4e-28 100.5 0.1 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SrfB PF07520.11 GAX10353.1 - 0.15 9.9 0.1 0.2 9.5 0.1 1.1 1 0 0 1 1 1 0 Virulence factor SrfB Sulfatase PF00884.23 GAX10355.1 - 2.6e-65 220.8 0.1 3.5e-65 220.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 GAX10355.1 - 1.9e-12 48.0 0.0 3.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 GAX10355.1 - 1.3e-07 31.5 0.0 1.9e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase IQ PF00612.27 GAX10356.1 - 7.8e-28 93.6 75.4 0.044 13.6 1.5 15.3 15 0 0 15 15 15 12 IQ calmodulin-binding motif Abhydrolase_9_N PF15420.6 GAX10356.1 - 2.7 8.0 4.8 5.5 6.9 4.8 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PRIMA1 PF16101.5 GAX10356.1 - 3.1 7.9 16.1 1.1 9.3 7.0 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GAX10356.1 - 9 5.7 15.2 2.3 7.6 5.6 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RNase_T PF00929.24 GAX10357.1 - 3.2e-10 40.8 0.1 6.8e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Exonuclease PP2C PF00481.21 GAX10358.1 - 1.4e-27 97.0 1.5 5.7e-18 65.5 0.0 4.3 4 0 0 4 4 4 4 Protein phosphatase 2C Cyclin_N PF00134.23 GAX10360.1 - 6.6e-17 61.4 1.3 1.1e-16 60.7 1.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX10360.1 - 4.3e-06 26.8 0.0 4.4e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain EXS PF03124.14 GAX10361.1 - 3.8e-60 204.0 18.4 6.1e-60 203.3 18.4 1.3 1 0 0 1 1 1 1 EXS family FbpA PF05833.11 GAX10362.1 - 7.2e-35 120.6 16.2 3.2e-25 88.8 0.0 2.7 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 GAX10362.1 - 9.3e-33 113.1 0.0 4.7e-32 110.9 0.0 2.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 GAX10362.1 - 4.6e-27 94.0 0.0 4.6e-27 94.0 0.0 4.2 6 0 0 6 6 6 1 NFACT protein C-terminal domain Fucose_iso_N2 PF07882.12 GAX10362.1 - 0.0017 17.9 2.3 0.44 10.1 0.9 3.1 2 0 0 2 2 2 2 L-fucose isomerase, second N-terminal domain Pro_isomerase PF00160.21 GAX10363.1 - 4.7e-10 40.0 0.0 1e-09 38.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med21 PF11221.8 GAX10363.1 - 0.011 16.0 1.2 0.018 15.3 1.2 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Syntaxin-6_N PF09177.11 GAX10363.1 - 0.027 15.0 1.2 0.068 13.7 1.2 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Flu_M1_C PF08289.11 GAX10363.1 - 0.027 14.7 1.5 0.044 14.0 1.0 1.6 1 1 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain EzrA PF06160.12 GAX10363.1 - 0.041 12.1 6.7 0.057 11.6 6.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 GAX10363.1 - 0.064 13.7 6.0 0.12 12.8 6.0 1.4 1 0 0 1 1 1 0 Fez1 Herpes_UL6 PF01763.16 GAX10363.1 - 0.12 10.9 5.3 0.55 8.7 4.9 1.9 2 0 0 2 2 2 0 Herpesvirus UL6 like SOGA PF11365.8 GAX10363.1 - 0.12 13.5 6.8 0.25 12.5 6.8 1.5 1 0 0 1 1 1 0 Protein SOGA SLIDE PF09111.10 GAX10363.1 - 0.66 10.0 5.7 0.48 10.5 1.5 2.2 1 1 1 2 2 2 0 SLIDE Uso1_p115_C PF04871.13 GAX10363.1 - 3.1 8.2 8.5 6 7.3 8.5 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pro_isomerase PF00160.21 GAX10364.1 - 1e-10 42.1 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Flu_M1_C PF08289.11 GAX10364.1 - 0.0045 17.2 0.6 0.009 16.2 0.6 1.5 1 0 0 1 1 1 1 Influenza Matrix protein (M1) C-terminal domain Rx_N PF18052.1 GAX10364.1 - 0.12 12.6 0.4 0.28 11.5 0.2 1.6 2 0 0 2 2 2 0 Rx N-terminal domain I_LWEQ PF01608.17 GAX10364.1 - 0.5 10.6 4.6 0.84 9.9 4.6 1.2 1 0 0 1 1 1 0 I/LWEQ domain Pro_isomerase PF00160.21 GAX10365.1 - 9.3e-11 42.2 0.0 1.9e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sec1 PF00995.23 GAX10365.1 - 0.0094 15.2 0.9 0.012 14.9 0.9 1.2 1 0 0 1 1 1 1 Sec1 family CBX7_C PF17218.3 GAX10365.1 - 0.05 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 CBX family C-terminal motif FapA PF03961.13 GAX10365.1 - 0.059 12.0 1.4 0.078 11.6 1.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A XkdW PF09636.10 GAX10365.1 - 0.1 12.7 0.4 0.31 11.1 0.4 1.8 1 0 0 1 1 1 0 XkdW protein IL2 PF00715.17 GAX10365.1 - 0.11 12.4 1.6 0.18 11.7 1.6 1.3 1 0 0 1 1 1 0 Interleukin 2 OmpH PF03938.14 GAX10365.1 - 0.54 10.6 7.4 0.97 9.8 7.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Muted PF14942.6 GAX10365.1 - 0.72 10.2 5.9 1.4 9.3 5.9 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Zip PF02535.22 GAX10368.1 - 1.2e-21 77.4 0.5 1.9e-21 76.6 0.5 1.2 1 1 0 1 1 1 1 ZIP Zinc transporter Prenyltrans PF00432.21 GAX10369.1 - 3.3e-22 77.9 9.2 5.5e-05 22.8 0.0 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat 5_3_exonuc_N PF02739.16 GAX10371.1 - 2.1e-49 167.5 0.0 3.6e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 GAX10371.1 - 2.4e-27 95.4 0.0 5.9e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GAX10371.1 - 0.034 14.8 0.0 0.098 13.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain NYN_YacP PF05991.11 GAX10371.1 - 0.045 13.7 2.6 0.98 9.3 0.0 3.1 4 0 0 4 4 4 0 YacP-like NYN domain HHH_2 PF12826.7 GAX10371.1 - 0.056 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF819 PF05684.12 GAX10372.1 - 6.5e-34 117.6 17.9 6.5e-34 117.6 17.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF819) Glt_symporter PF03616.14 GAX10372.1 - 0.00086 18.1 10.5 0.0016 17.2 10.5 1.4 1 0 0 1 1 1 1 Sodium/glutamate symporter CobN-Mg_chel PF02514.16 GAX10372.1 - 0.15 9.8 0.0 0.2 9.4 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase SET PF00856.28 GAX10373.1 - 1.4e-13 51.6 0.0 2.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 GAX10373.1 - 5.9e-11 43.2 0.6 1.1e-10 42.3 0.1 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding FmdA_AmdA PF03069.15 GAX10374.1 - 6.9e-28 97.6 0.0 3.5e-27 95.3 0.0 1.9 1 1 0 1 1 1 1 Acetamidase/Formamidase family CIAPIN1 PF05093.13 GAX10375.1 - 2.5e-14 53.6 15.0 1.2e-13 51.4 3.7 3.3 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MFS_1 PF07690.16 GAX10376.1 - 1.7e-08 33.8 12.6 1.7e-08 33.8 12.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PPR_2 PF13041.6 GAX10377.1 - 2.5e-37 126.8 0.5 1.1e-09 38.3 0.0 8.9 9 2 2 11 11 11 5 PPR repeat family PPR_3 PF13812.6 GAX10377.1 - 9.2e-29 99.3 4.6 5e-07 29.7 0.0 7.1 5 2 2 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.20 GAX10377.1 - 2.8e-23 80.5 0.0 0.0011 19.1 0.0 9.4 10 0 0 10 10 10 5 PPR repeat PPR_1 PF12854.7 GAX10377.1 - 1.1e-12 47.4 4.3 0.41 10.4 0.4 7.7 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 GAX10377.1 - 1.4e-10 40.9 6.2 2.8e-06 26.8 0.0 4.0 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP Smr PF01713.21 GAX10377.1 - 0.00064 20.0 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 Smr domain tRNA_synt_1c_R1 PF04558.15 GAX10377.1 - 0.012 15.6 0.0 3.2 7.7 0.0 3.3 2 1 1 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 KH_1 PF00013.29 GAX10380.1 - 2.2e-11 43.4 0.0 2.3e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 GAX10380.1 - 1.4e-05 24.8 0.1 0.0036 17.2 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 GAX10380.1 - 9.1e-05 22.2 0.0 0.0048 16.7 0.0 2.3 2 0 0 2 2 2 1 KH domain DUF2530 PF10745.9 GAX10380.1 - 0.021 15.1 1.2 0.25 11.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) WD40 PF00400.32 GAX10381.1 - 3.6e-11 43.4 12.7 0.0071 17.2 0.2 7.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX10381.1 - 0.00034 20.9 0.0 0.29 11.4 0.0 4.0 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX10381.1 - 0.0017 17.4 0.3 2.3 7.1 0.0 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAX10381.1 - 0.084 12.8 1.2 4.8 7.2 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MtN3_slv PF03083.16 GAX10382.1 - 1.2e-25 89.3 5.2 8.1e-18 64.2 1.2 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange YcgL PF05166.13 GAX10382.1 - 0.043 14.2 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 YcgL domain 2OG-FeII_Oxy PF03171.20 GAX10384.1 - 6.9e-06 26.5 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_8 PF01270.17 GAX10384.1 - 0.1 11.4 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 DUF4129 PF13559.6 GAX10385.1 - 0.081 13.2 7.8 0.061 13.6 5.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) UVR PF02151.19 GAX10385.1 - 0.12 12.1 2.3 0.29 10.9 2.3 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif Methyltransf_28 PF02636.17 GAX10386.1 - 3.3e-60 203.9 0.0 4.7e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CorA PF01544.18 GAX10387.1 - 5.2e-06 26.0 0.8 1.9e-05 24.1 0.3 2.1 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein Acetyltransf_1 PF00583.25 GAX10388.1 - 1.2e-11 44.9 0.0 1.4e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX10388.1 - 2.9e-09 37.2 0.0 4.6e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX10388.1 - 5.6e-08 32.8 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX10388.1 - 1.6e-07 31.2 0.0 3.8e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 GAX10388.1 - 0.0039 17.9 0.0 0.0051 17.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAX10388.1 - 0.035 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase CYTH PF01928.21 GAX10389.1 - 3.7e-18 66.1 0.0 7.2e-18 65.1 0.0 1.4 1 1 0 1 1 1 1 CYTH domain HSF_DNA-bind PF00447.17 GAX10390.1 - 3.3e-20 72.5 0.0 6.6e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Hydrolase_6 PF13344.6 GAX10391.1 - 1.8e-29 101.8 0.0 3.2e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX10391.1 - 2.5e-20 72.3 0.0 7.7e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX10391.1 - 7.1e-09 36.3 0.1 2.6e-08 34.4 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX10391.1 - 8.1e-08 32.6 0.1 0.0015 18.7 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAX10391.1 - 0.0017 18.0 0.0 0.014 15.0 0.0 2.2 2 1 0 2 2 2 1 Mitochondrial PGP phosphatase RVT_2 PF07727.14 GAX10392.1 - 1.3e-40 139.5 0.0 3.2e-40 138.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX10392.1 - 0.00019 21.4 3.5 0.00047 20.1 3.5 1.8 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 GAX10392.1 - 0.00021 21.1 0.0 0.00047 19.9 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain FA_desaturase PF00487.24 GAX10393.1 - 2.5e-24 86.5 18.8 3.8e-24 85.9 18.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase PLAC8 PF04749.17 GAX10395.1 - 0.00021 22.2 4.4 0.00029 21.8 4.4 1.2 1 0 0 1 1 1 1 PLAC8 family ARF7EP_C PF14949.6 GAX10395.1 - 0.027 15.1 1.5 0.033 14.8 1.5 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus zf-CCHC PF00098.23 GAX10396.1 - 2.3e-07 30.6 5.0 4.1e-07 29.8 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GAX10396.1 - 0.043 13.8 1.7 0.085 12.8 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GAX10396.1 - 9.7 6.0 9.9 0.056 13.2 1.2 1.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.14 GAX10397.1 - 2.6e-38 132.1 0.0 4.4e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLAC8 PF04749.17 GAX10397.1 - 1.6e-11 45.0 2.4 1.6e-11 45.0 2.4 2.4 3 0 0 3 3 3 1 PLAC8 family rve PF00665.26 GAX10397.1 - 5.5e-06 26.6 0.1 1.7e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 GAX10397.1 - 5.8e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Peptidase_M23 PF01551.22 GAX10398.1 - 4e-17 62.2 0.0 1.4e-16 60.5 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M23 RnfC_N PF13375.6 GAX10398.1 - 0.027 14.4 0.1 0.066 13.2 0.1 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 GAX10398.1 - 0.17 11.7 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF1336 PF07059.12 GAX10399.1 - 3.5e-17 63.2 0.0 5.7e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) SufE PF02657.15 GAX10399.1 - 1.7e-13 50.5 0.0 3.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Fe-S metabolism associated domain START PF01852.19 GAX10399.1 - 2.9e-13 49.7 0.0 5.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 START domain PH PF00169.29 GAX10399.1 - 0.00033 21.1 0.2 0.0049 17.4 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 GAX10399.1 - 0.15 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain SufE PF02657.15 GAX10400.1 - 1.7e-08 34.4 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain DEAD PF00270.29 GAX10401.1 - 1.4e-43 148.7 0.0 2.9e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX10401.1 - 2.1e-27 95.7 0.1 6.6e-27 94.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX10401.1 - 3.4e-05 23.9 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAX10401.1 - 0.026 13.8 1.9 0.16 11.3 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PGM_PMM_I PF02878.16 GAX10404.1 - 1.7e-29 102.3 0.0 2.6e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAX10404.1 - 1.6e-23 83.1 0.0 9.3e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAX10404.1 - 7.2e-11 42.6 0.0 2.5e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ATG22 PF11700.8 GAX10405.1 - 1.6e-15 56.7 26.5 2.7e-12 46.1 16.6 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAX10405.1 - 6e-11 41.9 27.6 6e-11 41.9 27.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 GAX10406.1 - 1e-14 54.8 0.0 3.4e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX10406.1 - 2.3e-11 43.7 0.1 4e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX10406.1 - 3.6e-10 40.1 0.1 6.8e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAX10406.1 - 2.5e-05 24.5 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX10406.1 - 6.4e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX10406.1 - 0.00019 21.4 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAX10406.1 - 0.0018 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 GAX10406.1 - 0.01 16.5 0.2 0.024 15.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-RING_4 PF14570.6 GAX10407.1 - 2.5e-21 75.2 14.3 3.8e-21 74.6 14.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 GAX10407.1 - 2.9e-06 27.0 0.0 7.9e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 GAX10407.1 - 3.5e-06 26.8 10.4 6e-06 26.0 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 GAX10407.1 - 0.012 15.7 4.2 0.025 14.7 4.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 GAX10407.1 - 1.7 8.5 6.1 3.5 7.6 6.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE_2 PF02318.16 GAX10407.1 - 3.5 7.9 7.1 6.7 7.0 7.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger NOC3p PF07540.11 GAX10408.1 - 8.7e-24 83.8 1.9 1.3e-23 83.3 0.1 2.3 2 1 1 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 GAX10408.1 - 5.7e-18 65.5 0.1 5.7e-18 65.5 0.1 2.6 2 1 0 2 2 2 1 CBF/Mak21 family SAT PF16073.5 GAX10408.1 - 2.3 7.9 7.8 0.39 10.4 2.7 2.4 3 1 1 4 4 4 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Ras PF00071.22 GAX10409.1 - 4.6e-59 198.6 0.0 5.2e-59 198.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX10409.1 - 2.6e-33 114.8 0.0 4e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX10409.1 - 3.8e-14 52.5 0.0 4.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX10409.1 - 0.0026 17.8 0.0 0.0044 17.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX10409.1 - 0.032 14.1 0.0 7.5 6.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 GAX10409.1 - 0.051 12.9 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 GAX10409.1 - 0.15 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF3079 PF11278.8 GAX10409.1 - 3.8 7.4 7.0 4.5 7.2 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3079) SWIRM PF04433.17 GAX10410.1 - 6.1e-15 55.3 0.0 1.8e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAX10410.1 - 4.6e-11 42.5 2.6 1.1e-10 41.3 2.6 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 MCCD1 PF15707.5 GAX10410.1 - 1.4 9.4 7.2 0.11 13.0 1.7 2.0 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 PP2C PF00481.21 GAX10411.1 - 1.9e-35 122.7 0.0 2.5e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX10411.1 - 1.3e-07 31.4 0.2 1.4e-05 24.9 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 GAX10411.1 - 6.8e-05 22.9 0.3 0.00064 19.7 0.2 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Seryl_tRNA_N PF02403.22 GAX10412.1 - 0.12 12.6 1.3 0.41 10.9 0.0 2.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain MORN PF02493.20 GAX10413.1 - 3.2e-24 83.3 31.6 5.7e-06 25.9 2.0 7.3 7 0 0 7 7 7 7 MORN repeat zf-NADH-PPase PF09297.11 GAX10413.1 - 0.025 14.2 0.4 0.057 13.1 0.4 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain MORN_2 PF07661.13 GAX10413.1 - 0.71 10.3 10.7 12 6.5 0.1 4.2 4 0 0 4 4 4 0 MORN repeat variant DUF2183 PF09949.9 GAX10414.1 - 0.037 14.3 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) DHHC PF01529.20 GAX10415.1 - 1.4e-33 115.8 5.8 1.4e-33 115.8 5.8 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Adap_comp_sub PF00928.21 GAX10416.1 - 2.3e-86 289.5 0.2 3e-86 289.1 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAX10416.1 - 2.7e-05 24.1 0.2 5.5e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 GAX10416.1 - 0.0021 17.6 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain TauE PF01925.19 GAX10417.1 - 1.3e-23 83.9 33.9 7.2e-13 48.7 7.9 2.9 2 1 0 3 3 3 2 Sulfite exporter TauE/SafE PBP1_TM PF14812.6 GAX10417.1 - 0.022 15.1 13.1 0.036 14.4 1.8 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRRC37AB_C PF14914.6 GAX10417.1 - 0.17 11.8 1.7 0.68 9.8 1.7 2.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain OAD_gamma PF04277.13 GAX10417.1 - 1.6 9.4 0.0 1.6 9.4 0.0 3.6 4 1 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Wzy_C_2 PF11846.8 GAX10417.1 - 3.1 7.7 5.7 7.2 6.5 0.3 3.1 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Sid-5 PF17204.3 GAX10417.1 - 3.1 8.0 4.0 45 4.3 0.2 3.5 3 0 0 3 3 3 0 Sid-5 family Ac76 PF05814.11 GAX10417.1 - 7 6.7 8.3 3.8 7.6 0.2 3.2 3 1 0 3 3 3 0 Orf76 (Ac76) ODV-E18 PF10717.9 GAX10417.1 - 9.6 6.2 6.5 20 5.1 1.1 2.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 START PF01852.19 GAX10418.1 - 0.00025 20.5 0.0 0.0013 18.2 0.0 1.9 1 1 0 1 1 1 1 START domain 2OG-FeII_Oxy_3 PF13640.6 GAX10420.1 - 0.05 14.5 0.0 0.087 13.7 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SET PF00856.28 GAX10421.1 - 1.7e-15 57.8 0.0 6.5e-15 55.9 0.0 2.0 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.16 GAX10422.1 - 4.7e-45 154.1 27.2 2.5e-44 151.7 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAX10422.1 - 3.7e-06 25.5 1.7 0.044 12.1 0.0 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 GAX10422.1 - 2.6e-05 23.7 1.4 2.6e-05 23.7 1.4 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CAP_N PF01213.19 GAX10423.1 - 4.5e-47 161.1 0.0 7e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 GAX10423.1 - 8.3e-45 152.2 5.6 1.2e-44 151.7 5.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 GAX10423.1 - 0.0073 16.0 3.5 0.013 15.3 3.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Peptidase_M17 PF00883.21 GAX10424.1 - 3.5e-100 335.3 0.4 4.7e-100 334.9 0.4 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 GAX10424.1 - 2.8e-09 37.3 2.0 6.1e-09 36.2 0.2 2.2 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 DUF2214 PF09980.9 GAX10425.1 - 4.7e-43 146.5 0.9 1e-42 145.4 0.3 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2214) Tetraspanin PF00335.20 GAX10425.1 - 5 6.8 6.0 0.9 9.2 1.6 2.0 2 1 1 3 3 3 0 Tetraspanin family TPR_12 PF13424.6 GAX10426.1 - 8.2e-95 311.2 39.1 1e-16 60.9 0.2 9.8 5 3 5 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 GAX10426.1 - 9.8e-83 270.1 53.7 9e-10 38.1 0.1 15.2 15 1 0 15 15 15 13 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10426.1 - 2.3e-59 195.0 24.8 3.8e-05 23.3 0.0 15.3 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10426.1 - 5.1e-50 163.6 29.2 5.9e-05 22.9 0.1 15.2 15 2 1 16 16 16 10 Tetratricopeptide repeat TPR_7 PF13176.6 GAX10426.1 - 6.3e-44 144.8 33.8 0.00032 20.5 0.0 14.2 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10426.1 - 2.2e-40 133.5 18.4 0.00092 19.2 0.0 14.5 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10426.1 - 2.8e-26 91.9 20.5 0.0028 18.3 0.1 11.9 9 3 2 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10426.1 - 6e-26 89.9 15.9 0.00065 19.3 0.1 12.8 12 1 1 13 13 12 6 TPR repeat TPR_MalT PF17874.1 GAX10426.1 - 1.2e-24 87.3 24.8 2.6e-11 43.5 1.7 5.7 2 2 3 5 5 5 5 MalT-like TPR region TPR_6 PF13174.6 GAX10426.1 - 4.8e-19 67.7 18.8 0.81 10.5 0.0 13.5 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX10426.1 - 1.5e-18 65.9 33.9 0.44 11.5 0.0 13.4 13 1 1 14 14 13 3 Tetratricopeptide repeat MIT PF04212.18 GAX10426.1 - 8.6e-12 45.0 17.2 1.1 9.4 0.0 10.5 11 0 0 11 11 11 2 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 GAX10426.1 - 9.9e-12 44.4 5.4 2.7 8.6 0.0 9.6 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX10426.1 - 1.8e-08 34.7 20.7 0.016 15.7 0.0 8.5 8 2 2 10 10 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAX10426.1 - 1.6e-07 31.3 0.1 14 6.6 0.1 8.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10426.1 - 5.2e-07 29.7 8.2 3.6 7.8 0.2 6.9 5 1 1 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.6 GAX10426.1 - 8.6e-07 28.7 7.6 0.0042 16.6 0.0 5.1 4 2 0 5 5 5 2 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 GAX10426.1 - 1e-06 28.2 13.0 3.8 6.6 0.0 8.7 8 1 3 11 11 11 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX10426.1 - 2.9e-06 27.1 3.8 0.22 11.2 0.1 5.8 2 2 3 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 GAX10426.1 - 9.5e-06 25.8 13.0 1.9 8.8 0.0 8.4 4 3 5 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 GAX10426.1 - 0.00014 21.6 16.1 3.6 7.3 0.0 8.1 4 4 2 8 8 8 1 26S proteasome subunit RPN7 ANAPC5 PF12862.7 GAX10426.1 - 0.0056 16.7 18.0 5.1 7.2 0.0 8.3 5 2 2 9 9 9 1 Anaphase-promoting complex subunit 5 TPR_5 PF12688.7 GAX10426.1 - 0.0061 16.8 11.5 0.74 10.1 0.0 5.6 4 3 1 6 6 6 2 Tetratrico peptide repeat PPR PF01535.20 GAX10426.1 - 0.0071 16.5 3.5 21 5.7 0.0 7.2 9 0 0 9 9 7 0 PPR repeat DUF627 PF04781.12 GAX10426.1 - 0.03 14.3 12.0 0.41 10.7 0.2 5.8 6 1 0 7 7 6 0 Protein of unknown function (DUF627) Glyoxalase PF00903.25 GAX10426.1 - 0.05 13.8 0.5 8.6 6.6 0.0 3.6 3 2 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SHNi-TPR PF10516.9 GAX10426.1 - 0.059 12.8 9.5 22 4.6 0.0 6.6 8 0 0 8 8 8 0 SHNi-TPR DUF3856 PF12968.7 GAX10426.1 - 0.61 10.1 6.7 36 4.4 0.0 5.8 4 3 0 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 GAX10426.1 - 0.99 9.5 17.0 3.1 7.9 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR_2 PF13041.6 GAX10426.1 - 1.1 9.5 3.3 45 4.4 0.0 4.9 7 0 0 7 7 5 0 PPR repeat family Glyco_hydro_2_C PF02836.17 GAX10427.1 - 2.3e-85 286.4 0.0 3.2e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 GAX10427.1 - 2.7e-62 210.6 0.0 4.2e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 GAX10427.1 - 9.7e-39 133.0 0.1 2.9e-38 131.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 GAX10427.1 - 1.2e-11 44.9 0.0 4e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 GAX10427.1 - 6.4e-09 36.5 0.0 1.6e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 APG9 PF04109.16 GAX10428.1 - 1.6e-95 320.9 0.6 2e-95 320.6 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF4720 PF15846.5 GAX10428.1 - 0.16 11.9 0.4 0.63 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4720) Mtc PF03820.17 GAX10429.1 - 2e-92 309.6 0.0 3.1e-92 309.0 0.0 1.3 1 0 0 1 1 1 1 Tricarboxylate carrier RVT_2 PF07727.14 GAX10430.1 - 8.6e-15 55.0 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 GAX10430.1 - 1.8e-06 27.7 0.0 4.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 GAX10430.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Apolipoprotein PF01442.18 GAX10431.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2457 PF10446.9 GAX10432.1 - 0.64 9.1 9.0 0.76 8.9 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ocnus PF05005.15 GAX10434.1 - 1.4e-15 57.4 0.0 2.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) PseudoU_synth_2 PF00849.22 GAX10434.1 - 5.4e-13 49.3 0.4 7.7e-12 45.6 0.4 2.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_M44 PF03410.13 GAX10434.1 - 0.047 12.3 0.0 0.066 11.8 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox Gelsolin PF00626.22 GAX10435.1 - 2.6e-25 88.1 0.2 1.5e-11 44.0 0.0 4.0 4 0 0 4 4 4 3 Gelsolin repeat Clat_adaptor_s PF01217.20 GAX10436.1 - 5.4e-07 29.6 0.0 2e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Exo_endo_phos PF03372.23 GAX10437.1 - 7.8e-22 77.9 0.1 1.1e-21 77.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAX10437.1 - 0.017 14.9 0.7 0.18 11.6 0.1 2.7 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Peptidase_U32 PF01136.19 GAX10437.1 - 0.082 12.0 0.0 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Peptidase family U32 HSP70 PF00012.20 GAX10438.1 - 4.8e-257 854.0 14.8 5.5e-257 853.8 14.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX10438.1 - 5.8e-19 68.1 1.8 7.6e-18 64.4 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAX10438.1 - 0.00017 21.3 0.0 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4624 PF15417.6 GAX10438.1 - 0.0055 16.5 0.1 2 8.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4624) Hydantoinase_A PF01968.18 GAX10438.1 - 0.0066 15.8 1.0 0.046 13.0 0.2 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.6 GAX10438.1 - 0.021 15.2 5.1 1.4 9.4 1.7 3.6 2 1 0 2 2 2 0 Cell division protein FtsA DUF4795 PF16043.5 GAX10438.1 - 0.047 13.3 4.6 1.3 8.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DDR PF08841.10 GAX10438.1 - 0.066 12.2 2.9 0.45 9.5 0.3 2.6 2 1 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain zf-C4H2 PF10146.9 GAX10438.1 - 0.47 10.7 3.0 4.9 7.4 1.2 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein HU-CCDC81_bac_2 PF18175.1 GAX10438.1 - 0.53 10.2 3.9 1.4 8.8 0.4 3.0 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 MutS_III PF05192.18 GAX10438.1 - 1.8 8.7 6.9 0.75 10.0 0.8 2.3 2 1 0 2 2 2 0 MutS domain III Spectrin PF00435.21 GAX10438.1 - 2.6 8.6 13.5 0.2 12.1 1.1 3.3 2 1 1 3 3 3 0 Spectrin repeat bZIP_1 PF00170.21 GAX10439.1 - 0.0009 19.3 9.5 0.0009 19.3 9.5 1.9 2 1 0 2 2 2 1 bZIP transcription factor Atg14 PF10186.9 GAX10439.1 - 0.032 13.3 9.0 0.045 12.8 9.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 GAX10439.1 - 0.049 13.9 4.0 0.049 13.9 4.0 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Ndc1_Nup PF09531.10 GAX10439.1 - 0.36 9.5 6.2 0.37 9.4 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HAUS6_N PF14661.6 GAX10439.1 - 0.64 9.6 10.8 0.89 9.1 10.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.19 GAX10439.1 - 0.77 7.6 5.5 0.97 7.3 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 GAX10439.1 - 1.1 9.4 20.7 0.1 12.7 10.5 3.2 1 1 2 3 3 3 0 Basic region leucine zipper SOBP PF15279.6 GAX10439.1 - 5.5 7.5 11.8 7.7 7.0 11.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein bZIP_Maf PF03131.17 GAX10439.1 - 5.9 7.5 16.5 12 6.4 15.2 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor ZapB PF06005.12 GAX10439.1 - 8.4 6.9 18.3 7.8 7.0 9.8 2.2 2 0 0 2 2 2 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 GAX10440.1 - 0.16 12.0 3.0 0.29 11.2 3.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EloA-BP1 PF15870.5 GAX10440.1 - 0.29 11.4 6.5 0.041 14.1 2.7 1.5 2 0 0 2 2 2 0 ElonginA binding-protein 1 Peptidase_M16_M PF16187.5 GAX10441.1 - 1.3e-70 237.9 0.1 2e-70 237.3 0.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX10441.1 - 4.5e-33 114.3 0.1 8.2e-33 113.5 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX10441.1 - 5e-27 95.1 0.1 4.5e-20 72.4 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Pkinase PF00069.25 GAX10442.1 - 1.8e-40 139.0 0.0 4.4e-20 72.1 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10442.1 - 1.8e-12 47.1 0.0 1.8e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX10442.1 - 0.013 14.3 0.6 0.032 13.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 GAX10442.1 - 0.036 13.4 0.1 0.09 12.1 0.1 1.6 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 GAX10442.1 - 0.25 10.3 0.0 0.38 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MS_channel PF00924.18 GAX10443.1 - 5.9e-22 78.2 0.1 5.9e-22 78.2 0.1 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel DEAD PF00270.29 GAX10444.1 - 4.7e-39 134.0 0.0 9.2e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX10444.1 - 1.1e-28 99.8 0.5 3.1e-25 88.7 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAX10444.1 - 4.9e-08 33.2 0.0 8.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAX10444.1 - 0.0013 18.2 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 GAX10444.1 - 0.0073 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Oxidored_FMN PF00724.20 GAX10445.1 - 1.7e-69 234.7 0.0 2.8e-68 230.7 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 GAX10445.1 - 1.3e-23 83.6 0.0 2.3e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX10445.1 - 3.4e-09 36.8 0.0 1.5e-08 34.8 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAX10445.1 - 8.1e-08 32.7 0.2 0.00021 21.8 0.0 3.3 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX10445.1 - 1.2e-07 31.5 0.1 3.3e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAX10445.1 - 1.6e-07 30.9 0.7 0.014 14.7 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX10445.1 - 3.8e-06 25.9 0.3 1.1e-05 24.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAX10445.1 - 3.6e-05 23.0 0.0 6.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAX10445.1 - 4.2e-05 23.5 0.0 0.0074 16.2 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 GAX10445.1 - 7e-05 22.1 0.1 0.00022 20.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 GAX10445.1 - 0.00027 20.6 6.4 0.00028 20.6 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 GAX10445.1 - 0.00068 19.6 0.0 0.0071 16.3 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K_oxygenase PF13434.6 GAX10445.1 - 0.0019 17.4 0.0 0.34 10.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 GAX10445.1 - 0.0062 16.2 0.1 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 GAX10445.1 - 0.0098 16.1 0.1 0.18 11.9 0.0 3.1 4 1 1 5 5 5 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 GAX10445.1 - 0.01 15.2 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.14 GAX10445.1 - 0.02 14.5 0.2 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 GAX10445.1 - 0.058 12.7 0.2 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAX10445.1 - 0.1 11.9 0.0 7.7 5.8 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 GAX10445.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ABC1 PF03109.16 GAX10447.1 - 7.2e-16 58.4 0.0 1.4e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.17 GAX10447.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Aminotran_1_2 PF00155.21 GAX10448.1 - 9.1e-84 281.7 0.0 1e-83 281.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ILEI PF15711.5 GAX10448.1 - 0.012 16.1 0.0 0.062 13.8 0.0 2.0 2 0 0 2 2 2 0 Interleukin-like EMT inducer CbiA PF01656.23 GAX10449.1 - 0.03 14.4 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 GAX10449.1 - 0.052 13.0 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase UPF0004 PF00919.20 GAX10449.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 LpxK PF02606.14 GAX10449.1 - 0.098 11.7 0.0 3.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase AA_kinase PF00696.28 GAX10450.1 - 5.5e-18 65.4 0.1 3.2e-17 63.0 0.1 1.9 1 1 0 1 1 1 1 Amino acid kinase family Methyltransf_11 PF08241.12 GAX10451.1 - 4.8e-12 46.4 0.0 7.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10451.1 - 1.3e-08 35.4 0.0 2.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX10451.1 - 4.6e-08 33.1 0.0 5.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX10451.1 - 8.5e-08 32.1 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX10451.1 - 0.0001 21.7 0.0 0.00013 21.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX10451.1 - 0.0065 17.2 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Patatin PF01734.22 GAX10452.1 - 7.6e-13 49.1 0.0 1.7e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase PseudoU_synth_2 PF00849.22 GAX10453.1 - 2.2e-14 53.9 0.0 3.2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Chorismate_bind PF00425.18 GAX10454.1 - 9.8e-84 280.9 0.0 1.6e-83 280.3 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 GAX10454.1 - 2.7e-38 131.6 0.0 4.8e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAX10454.1 - 8.8e-11 42.2 0.1 5.5e-10 39.6 0.1 2.3 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAX10454.1 - 1.9e-08 34.3 0.1 8.4e-08 32.2 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 ubiquitin PF00240.23 GAX10455.1 - 0.00018 21.2 0.0 0.00073 19.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 GAX10455.1 - 0.0046 17.0 0.0 0.0061 16.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Bmt2 PF11968.8 GAX10456.1 - 3.8e-42 144.6 0.0 5.2e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_8 PF05148.15 GAX10456.1 - 0.00011 22.1 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 GAX10456.1 - 0.0083 16.7 0.1 0.025 15.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX10456.1 - 0.013 15.3 0.0 0.1 12.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAX10456.1 - 0.077 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10456.1 - 0.13 13.0 0.0 0.38 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Spond_N PF06468.13 GAX10457.1 - 4.8e-14 52.9 0.0 8.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Spondin_N zf-MYND PF01753.18 GAX10458.1 - 1.6e-07 31.3 17.2 1.6e-07 31.3 17.2 2.3 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 GAX10458.1 - 0.054 13.8 9.4 0.16 12.3 9.4 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 GAX10458.1 - 1.2 9.3 9.8 2 8.6 6.8 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 GAX10458.1 - 1.3 8.9 15.7 0.29 11.0 10.6 2.5 2 1 0 2 2 2 0 HIT zinc finger FAA_hydrolase PF01557.18 GAX10459.1 - 2.5e-44 151.6 0.0 3.1e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TFIIE_alpha PF02002.17 GAX10460.1 - 4.2e-10 39.4 0.4 4.2e-10 39.4 0.4 2.2 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 GAX10460.1 - 0.22 11.0 1.3 0.57 9.7 1.3 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding UBA PF00627.31 GAX10461.1 - 4.6e-11 42.4 1.4 1.8e-10 40.5 1.2 2.2 2 0 0 2 2 2 1 UBA/TS-N domain PUB PF09409.10 GAX10461.1 - 3.3e-08 33.3 0.0 1.9e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 PUB domain UBA_4 PF14555.6 GAX10461.1 - 0.0079 16.0 0.3 0.018 14.8 0.3 1.7 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 GAX10461.1 - 0.019 14.7 0.1 0.052 13.3 0.1 1.8 1 0 0 1 1 1 0 CUE domain UBX PF00789.20 GAX10461.1 - 0.036 14.3 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 UBX domain HTH_8 PF02954.19 GAX10461.1 - 0.038 13.8 0.6 0.038 13.8 0.6 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family UIM PF02809.20 GAX10461.1 - 0.13 12.2 10.4 0.1 12.6 6.3 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Nucleoside_tran PF01733.18 GAX10462.1 - 1.3e-13 51.0 18.5 4.4e-11 42.7 6.0 3.2 3 1 0 3 3 3 2 Nucleoside transporter DAGAT PF03982.13 GAX10463.1 - 6.5e-34 117.2 0.0 8e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Isochorismatase PF00857.20 GAX10464.1 - 9.8e-09 35.6 0.3 0.00093 19.4 0.0 2.6 3 0 0 3 3 3 2 Isochorismatase family CN_hydrolase PF00795.22 GAX10465.1 - 0.043 13.1 0.0 0.13 11.6 0.0 1.6 1 1 1 2 2 2 0 Carbon-nitrogen hydrolase Ac110_PIF PF07280.11 GAX10465.1 - 0.8 9.5 0.0 0.8 9.5 0.0 2.3 3 0 0 3 3 3 0 Per os infectivity factor AC110 Metallophos PF00149.28 GAX10467.1 - 1.9e-06 28.5 1.6 2.8e-06 28.0 1.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4366 PF14283.6 GAX10467.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Sortase PF04203.13 GAX10467.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Sortase domain Peptidase_S49 PF01343.18 GAX10468.1 - 1.6e-29 102.9 0.0 3e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 GAX10468.1 - 0.00011 22.2 0.4 0.061 13.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase family S49 N-terminal MIF4G_like PF09088.11 GAX10470.1 - 1.2e-09 38.2 0.1 2e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 MIF4G like DUF2894 PF11445.8 GAX10470.1 - 0.18 12.2 0.6 1.9 8.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) CENP-B_dimeris PF09026.10 GAX10470.1 - 1.6 9.2 11.4 9.3 6.7 7.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SKA1 PF07160.12 GAX10471.1 - 2.5e-07 30.8 1.0 5.4e-07 29.7 0.9 1.5 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Chal_sti_synt_N PF00195.19 GAX10471.1 - 0.059 12.8 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF2721 PF11026.8 GAX10471.1 - 0.15 12.0 1.1 0.32 10.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Spectrin PF00435.21 GAX10471.1 - 0.81 10.2 8.1 0.079 13.5 1.1 2.8 4 0 0 4 4 4 0 Spectrin repeat G_glu_transpept PF01019.21 GAX10472.1 - 8.1e-118 394.4 0.0 1e-117 394.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PSD3 PF07626.11 GAX10473.1 - 0.056 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) DUF5435 PF17503.2 GAX10473.1 - 0.21 11.3 0.1 8.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5435) DUF3510 PF12022.8 GAX10474.1 - 7.7e-32 110.3 0.0 1.9e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) CorA PF01544.18 GAX10474.1 - 6.6 5.9 8.6 33 3.7 3.1 3.2 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein IPK PF03770.16 GAX10475.1 - 4.3e-36 124.6 0.0 1.9e-35 122.5 0.0 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase Pyr_redox_2 PF07992.14 GAX10476.1 - 6.8e-75 252.0 2.7 1e-74 251.5 2.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX10476.1 - 2.8e-43 146.6 0.4 1.3e-42 144.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX10476.1 - 1.2e-23 83.4 5.1 2.7e-20 72.7 0.3 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX10476.1 - 5e-10 39.1 1.1 5.6e-06 25.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX10476.1 - 4.3e-08 32.9 4.2 4.3e-08 32.9 4.2 2.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX10476.1 - 6.8e-08 32.0 8.9 1.9e-05 23.9 2.0 3.5 3 1 1 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.6 GAX10476.1 - 1.6e-07 31.4 0.6 0.0003 20.9 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAX10476.1 - 1.1e-06 28.0 8.6 4.7e-06 25.9 3.6 3.0 2 2 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAX10476.1 - 4.8e-06 26.0 1.7 0.0079 15.5 0.2 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAX10476.1 - 0.00035 19.4 10.9 0.0027 16.5 1.3 3.6 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.19 GAX10476.1 - 0.00037 19.9 4.5 0.11 11.7 1.2 2.5 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 GAX10476.1 - 0.0006 19.1 2.8 0.0029 16.9 0.9 3.0 3 1 0 3 3 3 1 Thi4 family 3HCDH_N PF02737.18 GAX10476.1 - 0.0028 17.6 1.0 0.0048 16.8 0.2 1.8 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 GAX10476.1 - 0.003 16.7 2.9 0.64 9.1 0.1 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 GAX10476.1 - 0.075 12.6 11.9 4.8 6.7 0.3 3.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX10476.1 - 0.11 11.5 0.8 1.5 7.8 0.5 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein DUF3801 PF12687.7 GAX10476.1 - 0.3 11.1 3.8 0.59 10.2 0.2 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF3801) NAD_binding_7 PF13241.6 GAX10476.1 - 0.89 10.0 3.3 3.4 8.2 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding RuBisCO_large PF00016.20 GAX10476.1 - 1.9 7.6 5.9 8.4 5.5 0.1 3.0 3 0 0 3 3 3 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Fe-S_biosyn PF01521.20 GAX10477.1 - 9.4e-18 64.4 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SAPS PF04499.15 GAX10478.1 - 1.6e-05 23.9 3.2 1.6e-05 23.9 3.2 4.7 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein CRT-like PF08627.10 GAX10479.1 - 1.8e-14 53.4 16.7 8e-11 41.5 6.6 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Cu-oxidase_2 PF07731.14 GAX10480.1 - 2e-13 50.3 4.5 2e-13 50.3 4.5 2.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAX10480.1 - 9.3e-10 38.6 0.0 4.2e-09 36.4 0.0 2.1 3 0 0 3 3 3 1 Multicopper oxidase MRP-L27 PF09809.9 GAX10481.1 - 1.1e-16 60.6 0.3 1.5e-16 60.2 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Membralin PF09746.9 GAX10482.1 - 2.1 7.3 4.3 2.8 6.9 4.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 GAX10482.1 - 6 3.9 16.4 7.1 3.6 16.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 GAX10482.1 - 7.7 4.5 11.1 8.7 4.3 11.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ras PF00071.22 GAX10483.1 - 7.2e-64 214.3 0.3 8.6e-64 214.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX10483.1 - 6.1e-36 123.3 0.1 1.1e-35 122.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX10483.1 - 6.6e-16 58.2 0.1 8.2e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX10483.1 - 1.2e-06 28.5 0.1 4e-06 26.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX10483.1 - 2.3e-06 27.3 0.3 5.5e-06 26.1 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAX10483.1 - 2.4e-06 27.1 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAX10483.1 - 6.9e-05 22.8 0.2 0.066 13.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAX10483.1 - 8e-05 22.1 0.1 0.00013 21.5 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAX10483.1 - 0.006 16.1 0.0 0.076 12.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B CENP-M PF11111.8 GAX10483.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_16 PF13191.6 GAX10483.1 - 0.013 15.9 0.0 0.019 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAX10483.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.6 1 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 GAX10483.1 - 0.03 13.5 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 GAX10483.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAX10483.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter RPN2_C PF18004.1 GAX10484.1 - 2.1e-33 115.5 9.1 3.4e-33 114.8 9.1 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 GAX10484.1 - 1.5e-23 82.0 19.8 1.2e-05 25.5 0.0 8.3 7 1 0 7 7 7 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAX10484.1 - 6e-16 58.6 7.4 8e-10 39.0 0.0 6.9 4 2 3 7 7 7 2 HEAT repeats TPR_5 PF12688.7 GAX10484.1 - 0.0028 17.9 0.7 7 6.9 0.1 4.0 4 0 0 4 4 4 2 Tetratrico peptide repeat HEAT PF02985.22 GAX10484.1 - 0.025 14.8 0.3 16 6.1 0.1 4.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 GAX10484.1 - 8.5 7.0 6.8 21 5.8 0.0 4.7 4 2 1 5 5 5 0 HEAT-like repeat RED_N PF07808.13 GAX10485.1 - 0.021 14.4 5.7 0.021 14.4 5.7 3.1 3 1 1 4 4 4 0 RED-like protein N-terminal region DUF3439 PF11921.8 GAX10485.1 - 0.12 12.3 0.4 0.33 10.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GAS PF13851.6 GAX10486.1 - 0.021 14.2 8.1 0.046 13.1 8.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 GAX10486.1 - 0.022 15.3 4.3 0.043 14.4 0.6 2.7 2 0 0 2 2 2 0 SlyX KxDL PF10241.9 GAX10486.1 - 0.25 11.7 5.1 1.1 9.6 5.1 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein ZapB PF06005.12 GAX10486.1 - 1.1 9.8 11.3 0.16 12.4 6.2 2.3 1 1 1 2 2 2 0 Cell division protein ZapB NEMO PF11577.8 GAX10486.1 - 1.1 9.3 5.6 2.9 8.0 5.6 1.7 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DivIC PF04977.15 GAX10486.1 - 1.9 8.3 4.7 1.9 8.3 2.8 2.0 1 1 1 2 2 2 0 Septum formation initiator HSF_DNA-bind PF00447.17 GAX10488.1 - 5.6e-19 68.6 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1280 PF06918.14 GAX10488.1 - 0.13 11.8 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) PBP1_TM PF14812.6 GAX10488.1 - 0.66 10.4 6.8 0.12 12.8 3.1 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VKG_Carbox PF05090.14 GAX10489.1 - 3.9e-29 101.8 14.2 3.9e-29 101.8 14.2 2.0 3 0 0 3 3 3 1 Vitamin K-dependent gamma-carboxylase Exo_endo_phos PF03372.23 GAX10490.1 - 2.1e-06 27.5 0.1 1.4e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family AAA PF00004.29 GAX10491.1 - 1.1e-25 90.6 0.0 4.3e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX10491.1 - 2.6e-05 24.7 0.4 0.0008 19.8 0.0 2.9 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAX10491.1 - 2.7e-05 24.5 0.6 0.0011 19.3 0.1 3.3 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAX10491.1 - 3.1e-05 24.2 0.0 0.00047 20.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAX10491.1 - 3.8e-05 23.2 0.1 7.3e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX10491.1 - 0.00058 19.9 0.2 0.016 15.2 0.2 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX10491.1 - 0.00083 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 GAX10491.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RsgA_GTPase PF03193.16 GAX10491.1 - 0.0021 18.0 0.0 0.02 14.8 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 GAX10491.1 - 0.0037 16.8 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region RuvB_N PF05496.12 GAX10491.1 - 0.006 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 GAX10491.1 - 0.008 15.6 0.1 1.1 8.6 0.0 2.5 3 0 0 3 3 3 1 Bacterial TniB protein NACHT PF05729.12 GAX10491.1 - 0.014 15.3 0.3 0.64 9.9 0.0 2.8 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 GAX10491.1 - 0.018 15.4 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GAX10491.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 GAX10491.1 - 0.079 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ATPase_2 PF01637.18 GAX10491.1 - 0.11 12.4 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 GAX10491.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 GAX10491.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GAX10491.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ank_5 PF13857.6 GAX10492.1 - 0.00066 19.9 0.8 1.7 9.0 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX10492.1 - 0.18 12.5 0.2 94 4.1 0.1 3.7 3 0 0 3 3 3 0 Ankyrin repeat Filo_glycop PF01611.16 GAX10492.1 - 0.31 9.9 7.8 0.49 9.3 7.8 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein Dicty_CAD PF05720.12 GAX10493.1 - 0.095 12.7 0.2 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Cell-cell adhesion domain DUF3336 PF11815.8 GAX10495.1 - 1.4e-21 76.7 4.1 3.5e-21 75.4 4.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAX10495.1 - 1.2e-20 74.6 0.0 2.5e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Aa_trans PF01490.18 GAX10496.1 - 4.4e-46 157.4 26.5 5.4e-46 157.1 26.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_23 PF13489.6 GAX10497.1 - 1.6e-08 34.6 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10497.1 - 2.5e-07 31.3 0.0 4.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10497.1 - 3.6e-07 30.8 0.0 5.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX10497.1 - 9.9e-07 28.7 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX10497.1 - 5.4e-05 23.8 0.0 0.00017 22.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX10497.1 - 6.6e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX10497.1 - 8.4e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 GAX10497.1 - 0.0029 17.0 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_17 PF12692.7 GAX10497.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase PrmA PF06325.13 GAX10497.1 - 0.039 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 GAX10497.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Glyoxalase_6 PF18029.1 GAX10498.1 - 0.00011 22.9 0.0 0.00014 22.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 GAX10498.1 - 0.00023 21.4 0.0 0.00029 21.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5_nucleotid_C PF02872.18 GAX10499.1 - 3.5e-22 79.3 0.0 4.5e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Lum_binding PF00677.17 GAX10500.1 - 2.4e-43 146.0 0.1 1.5e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ABC_tran_CTD PF16326.5 GAX10500.1 - 0.083 13.2 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain LSM PF01423.22 GAX10501.1 - 2.6e-17 62.3 0.1 3.4e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX10501.1 - 0.015 15.4 0.3 0.02 15.0 0.3 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 GAX10501.1 - 0.027 14.4 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BPL_C PF02237.17 GAX10501.1 - 0.028 14.3 0.9 0.049 13.5 0.9 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Hfq PF17209.3 GAX10501.1 - 0.046 13.4 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 Hfq protein DUF2642 PF10842.8 GAX10501.1 - 0.24 11.3 0.7 0.61 10.0 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) RsfS PF02410.15 GAX10502.1 - 5.8e-21 74.8 0.0 8.5e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Ank_2 PF12796.7 GAX10503.1 - 1.2e-16 61.0 0.0 9.7e-06 26.1 0.0 4.9 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX10503.1 - 5.6e-12 45.7 5.8 0.0029 17.9 0.0 6.2 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX10503.1 - 2.4e-10 40.4 13.9 0.12 12.9 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 GAX10503.1 - 4.2e-06 26.7 11.5 0.17 12.5 0.0 7.4 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 GAX10503.1 - 2e-05 25.0 5.9 0.21 12.2 0.0 5.7 4 2 3 7 7 7 3 Ankyrin repeats (many copies) PI3_PI4_kinase PF00454.27 GAX10504.1 - 4.4e-48 164.3 0.0 1.8e-47 162.2 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GAX10504.1 - 3.6e-12 45.9 0.5 1.3e-11 44.1 0.2 2.2 2 0 0 2 2 2 1 FATC domain UBA2_C PF16195.5 GAX10504.1 - 0.14 12.9 1.5 0.4 11.4 0.1 2.4 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Ubie_methyltran PF01209.18 GAX10506.1 - 4.9e-79 264.9 0.0 6.8e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GAX10506.1 - 3.7e-15 56.3 0.1 9.6e-15 55.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10506.1 - 6.8e-15 55.5 0.1 1.7e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX10506.1 - 6.6e-12 45.5 0.0 1.4e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10506.1 - 9.3e-12 45.6 0.2 1.9e-11 44.5 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX10506.1 - 1.4e-08 34.8 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PRK PF00485.18 GAX10507.1 - 2.9e-10 40.2 0.0 5.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAX10507.1 - 1.8e-06 28.5 0.0 4.8e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX10507.1 - 0.00027 20.3 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 GAX10507.1 - 0.00082 19.8 0.0 0.0019 18.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 GAX10507.1 - 0.00093 19.4 0.0 0.012 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 GAX10507.1 - 0.0028 16.7 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 GAX10507.1 - 0.014 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 GAX10507.1 - 0.027 14.7 0.0 0.047 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 GAX10507.1 - 0.028 14.3 0.0 4.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 GAX10507.1 - 0.036 14.0 0.0 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 GAX10507.1 - 0.037 14.5 0.2 0.86 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAX10507.1 - 0.042 13.9 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 GAX10507.1 - 0.059 13.0 0.0 9.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 GAX10507.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 GAX10507.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_30 PF13604.6 GAX10507.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAX10507.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 GAX10507.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX10507.1 - 0.21 10.9 0.0 0.41 10.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GAX10507.1 - 0.21 12.1 0.0 0.35 11.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter IIGP PF05049.13 GAX10507.1 - 0.24 10.4 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SMC_N PF02463.19 GAX10507.1 - 0.25 10.8 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain WD40 PF00400.32 GAX10508.1 - 3.8e-08 33.9 12.2 1.2e-07 32.3 0.2 4.8 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX10508.1 - 4.6e-05 23.6 0.1 0.015 15.6 0.1 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX10508.1 - 0.043 13.1 0.1 1.2 8.4 0.0 2.4 1 1 0 2 2 2 0 WD40-like domain Cyanate_lyase PF02560.14 GAX10509.1 - 3.3e-28 97.3 0.2 4.6e-28 96.9 0.2 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 GAX10509.1 - 2.8e-06 27.3 0.1 4.2e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 GAX10509.1 - 0.0096 16.3 0.3 0.016 15.5 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 GAX10509.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 ERCC4 PF02732.15 GAX10510.1 - 3.2e-17 63.2 0.3 6e-16 59.0 0.0 2.9 2 1 0 2 2 2 1 ERCC4 domain HVSL PF09749.9 GAX10510.1 - 0.021 14.3 0.4 0.035 13.6 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein HHH_5 PF14520.6 GAX10510.1 - 0.027 15.1 0.0 0.073 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ldt_C PF17969.1 GAX10510.1 - 0.1 13.3 0.5 9.7 7.0 0.1 3.1 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain SelB-wing_2 PF09106.11 GAX10510.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 Elongation factor SelB, winged helix IFN-gamma PF00714.17 GAX10510.1 - 0.2 11.5 1.7 2.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Interferon gamma PH PF00169.29 GAX10511.1 - 2.8e-19 69.6 0.1 3.3e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 GAX10511.1 - 3.1e-08 34.0 1.3 0.0032 17.9 0.0 3.2 3 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 GAX10511.1 - 0.0004 20.6 0.1 0.011 16.0 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain SlyX PF04102.12 GAX10511.1 - 0.04 14.5 0.8 0.13 12.9 0.8 1.9 1 0 0 1 1 1 0 SlyX PH_4 PF15404.6 GAX10511.1 - 0.062 13.1 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain MFS_1 PF07690.16 GAX10512.1 - 2.9e-40 138.3 39.0 1.2e-39 136.3 32.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAX10512.1 - 0.069 11.4 11.8 0.73 8.1 0.2 4.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family UQ_con PF00179.26 GAX10513.1 - 5.7e-19 68.2 0.0 2.3e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme AIG1 PF04548.16 GAX10513.1 - 0.0061 15.9 0.6 0.013 14.8 0.1 1.7 1 1 0 1 1 1 1 AIG1 family Kp4 PF09044.10 GAX10513.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Kp4 MYO10_CC PF16735.5 GAX10513.1 - 0.5 10.5 7.0 0.13 12.4 0.6 2.9 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain Pribosyltran PF00156.27 GAX10514.1 - 5.9e-10 38.9 0.3 1.2e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RSS_P20 PF11757.8 GAX10515.1 - 0.075 13.5 1.0 1.2 9.7 0.1 2.7 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain VASP_tetra PF08776.11 GAX10515.1 - 0.42 10.2 11.6 2.6 7.7 0.2 5.2 6 0 0 6 6 6 0 VASP tetramerisation domain Pkinase PF00069.25 GAX10517.1 - 1.8e-14 53.8 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10517.1 - 5.7e-10 38.9 0.0 8.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EPL1 PF10513.9 GAX10517.1 - 0.065 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like Cupin_7 PF12973.7 GAX10518.1 - 2e-32 111.0 0.0 2.4e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 GAX10518.1 - 0.0013 18.4 0.3 0.002 17.8 0.3 1.5 1 1 0 1 1 1 1 Cupin domain DMSP_lyase PF16867.5 GAX10518.1 - 0.0063 16.2 0.1 0.0082 15.8 0.1 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase LRR_8 PF13855.6 GAX10519.1 - 6.9e-26 89.8 32.0 1.6e-05 24.5 3.6 7.4 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 GAX10519.1 - 1.5e-25 88.8 22.5 0.0011 19.3 0.1 8.3 6 1 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 GAX10519.1 - 2.9e-06 27.7 3.1 1.3 9.8 0.1 6.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_1 PF00560.33 GAX10519.1 - 1.2e-05 25.2 28.8 2.6 8.9 0.2 10.8 10 3 0 10 10 10 2 Leucine Rich Repeat LRR_9 PF14580.6 GAX10519.1 - 0.0096 15.4 5.4 3.7 7.0 0.1 3.7 2 1 0 4 4 4 2 Leucine-rich repeat DUF411 PF04214.13 GAX10519.1 - 0.049 13.6 0.0 0.55 10.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF Dict-STAT-coil PF09267.10 GAX10519.1 - 0.064 13.6 0.2 32 5.0 0.0 3.6 4 1 0 4 4 4 0 Dictyostelium STAT, coiled coil LRR_6 PF13516.6 GAX10519.1 - 0.19 11.9 21.1 15 6.0 0.1 8.2 9 0 0 9 9 9 0 Leucine Rich repeat Coa1 PF08695.10 GAX10520.1 - 0.00013 21.6 0.1 0.00024 20.8 0.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Serinc PF03348.15 GAX10521.1 - 2.6e-74 250.7 5.2 3.1e-74 250.5 5.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF5506 PF17611.2 GAX10522.1 - 0.16 11.9 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5506) IFRD PF05004.13 GAX10524.1 - 9.5e-32 110.3 1.0 9.5e-32 110.3 1.0 1.5 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) DUF2974 PF11187.8 GAX10524.1 - 0.047 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_M16 PF00675.20 GAX10525.1 - 2.2e-53 180.3 0.3 3.5e-53 179.6 0.3 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX10525.1 - 3.8e-34 118.3 0.0 2.1e-33 115.9 0.0 2.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain MtrB PF05440.12 GAX10525.1 - 0.092 13.2 0.2 9.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B FKBP_C PF00254.28 GAX10526.1 - 3.5e-13 49.7 0.0 6.4e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Collagen_mid PF15984.5 GAX10527.1 - 0.028 14.2 0.3 0.087 12.6 0.3 1.8 1 1 0 1 1 1 0 Bacterial collagen, middle region TPR_12 PF13424.6 GAX10528.1 - 1.2e-06 28.7 4.8 0.00074 19.8 0.6 2.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX10528.1 - 3.5e-06 26.7 1.1 5.6e-05 22.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10528.1 - 8.2e-06 25.6 0.3 0.0025 17.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX10528.1 - 0.00012 21.9 0.9 0.00015 21.6 0.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.6 GAX10528.1 - 0.001 19.1 1.1 0.34 11.2 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10528.1 - 0.0015 18.2 0.3 0.072 12.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX10528.1 - 0.017 15.1 3.1 0.034 14.2 0.2 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX10528.1 - 0.032 14.9 1.0 8.5 7.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.6 GAX10529.1 - 9e-27 92.6 39.2 4.3e-08 32.8 0.7 6.7 2 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX10529.1 - 6.2e-25 86.9 38.9 3.2e-05 24.2 0.3 8.2 2 2 7 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX10529.1 - 4e-09 35.8 27.0 3.9 8.4 0.7 12.0 14 0 0 14 14 14 3 Leucine Rich Repeat LRR_2 PF07723.13 GAX10529.1 - 0.011 16.3 1.8 38 5.2 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 GAX10529.1 - 0.012 15.1 7.1 0.55 9.7 0.1 3.4 1 1 2 4 4 4 0 Leucine-rich repeat LRR_6 PF13516.6 GAX10529.1 - 0.024 14.7 32.5 1.6 9.0 0.0 10.0 11 0 0 11 11 11 0 Leucine Rich repeat DUF4131 PF13567.6 GAX10529.1 - 0.078 12.6 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 GAX10529.1 - 0.087 13.1 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) AAA_33 PF13671.6 GAX10530.1 - 6.9e-12 45.7 0.1 2.5e-05 24.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX10530.1 - 0.00036 21.1 0.2 0.008 16.7 0.1 2.4 1 1 2 3 3 3 1 AAA domain KTI12 PF08433.10 GAX10530.1 - 0.00051 19.6 0.4 0.046 13.2 0.0 2.1 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 GAX10530.1 - 0.00068 20.1 0.2 0.021 15.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX10530.1 - 0.0058 15.9 0.0 0.0096 15.2 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 GAX10530.1 - 0.0085 16.4 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAX10530.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain 6PF2K PF01591.18 GAX10530.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.6 GAX10530.1 - 0.045 14.1 0.0 0.056 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 GAX10530.1 - 0.047 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 GAX10530.1 - 0.048 14.1 0.0 0.081 13.4 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAX10530.1 - 0.05 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 GAX10530.1 - 0.052 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 GAX10530.1 - 0.058 13.9 0.1 0.19 12.2 0.0 1.8 1 1 1 2 2 2 0 ABC transporter AAA_29 PF13555.6 GAX10530.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 GAX10530.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PI_PP_I PF18363.1 GAX10530.1 - 0.073 13.3 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Thymidylate_kin PF02223.17 GAX10530.1 - 0.089 12.5 0.1 4.2 7.0 0.0 2.5 1 1 1 2 2 2 0 Thymidylate kinase MeaB PF03308.16 GAX10530.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 GAX10530.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX10530.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Beta_helix PF13229.6 GAX10531.1 - 3.7e-10 39.9 9.0 1.2e-09 38.2 9.0 1.9 1 1 0 1 1 1 1 Right handed beta helix region DUF1565 PF07602.11 GAX10531.1 - 0.00098 18.5 2.7 0.0038 16.6 1.4 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1565) HMG_box PF00505.19 GAX10532.1 - 4.7e-07 30.1 12.4 0.0011 19.4 0.1 3.3 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX10532.1 - 2.3e-06 28.1 4.1 2.3e-06 28.1 4.1 3.2 1 1 1 2 2 2 1 HMG-box domain Strep_SA_rep PF06696.11 GAX10532.1 - 0.054 13.5 5.3 0.38 10.8 0.6 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat YaeQ PF07152.12 GAX10532.1 - 0.1 12.2 2.4 0.17 11.5 2.4 1.2 1 0 0 1 1 1 0 YaeQ protein YABBY PF04690.13 GAX10532.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.1 2 0 0 2 2 2 0 YABBY protein SdrD_B PF17210.3 GAX10533.1 - 1.3e-58 196.1 6.4 3.7e-17 62.6 0.5 4.2 4 0 0 4 4 4 4 SdrD B-like domain SpaA PF17802.1 GAX10533.1 - 2.5e-08 34.1 0.6 0.037 14.4 0.0 4.3 4 0 0 4 4 4 2 Prealbumin-like fold domain Big_9 PF17963.1 GAX10533.1 - 9.5 7.0 7.9 7.2 7.4 0.1 4.0 2 2 1 3 3 3 0 Bacterial Ig domain RRF PF01765.19 GAX10534.1 - 3.5e-33 114.8 0.5 3.5e-33 114.8 0.5 1.9 2 0 0 2 2 2 1 Ribosome recycling factor SpoIIP PF07454.11 GAX10534.1 - 0.0019 17.7 1.4 0.0037 16.8 1.4 1.4 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) PSD5 PF07637.11 GAX10534.1 - 0.36 11.2 2.3 0.73 10.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) Spem1 PF15670.5 GAX10534.1 - 0.52 9.9 5.3 0.18 11.3 2.5 1.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 CDT1_C PF16679.5 GAX10534.1 - 0.93 10.0 8.6 14 6.2 4.5 3.2 2 2 1 3 3 3 0 DNA replication factor Cdt1 C-terminal domain DUF4746 PF15928.5 GAX10534.1 - 1.2 8.5 14.9 2.3 7.6 8.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) FtsX_ECD PF18075.1 GAX10534.1 - 3.4 8.3 9.9 1.8 9.2 6.0 2.4 2 0 0 2 2 2 0 FtsX extracellular domain Endonuclease_NS PF01223.23 GAX10535.1 - 3e-44 151.5 0.2 3.9e-44 151.1 0.2 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 GAX10535.1 - 0.029 14.5 0.1 0.054 13.6 0.1 1.4 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease ANAPC4 PF12896.7 GAX10537.1 - 6e-15 55.3 2.5 1e-14 54.5 2.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 GAX10537.1 - 2.4e-05 24.5 0.0 6.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain IQ PF00612.27 GAX10538.1 - 2.1e-84 269.4 254.9 0.00068 19.2 0.7 42.0 41 1 1 42 42 42 38 IQ calmodulin-binding motif PriCT_1 PF08708.11 GAX10538.1 - 0.036 13.8 0.8 0.59 9.9 0.2 3.1 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) TAF6_C PF07571.13 GAX10538.1 - 1.4 9.3 7.6 1.2 9.5 0.3 4.0 3 1 1 4 4 4 0 TAF6 C-terminal HEAT repeat domain SIS PF01380.22 GAX10542.1 - 1e-22 80.4 0.6 2.1e-08 34.1 0.2 4.0 3 1 0 3 3 3 3 SIS domain GATase_6 PF13522.6 GAX10542.1 - 8.3e-18 64.9 0.1 2e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX10542.1 - 5.3e-11 42.5 0.0 2e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain bact-PGI_C PF10432.9 GAX10542.1 - 0.019 15.0 0.4 2.4 8.2 0.0 3.4 2 1 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain GATase_4 PF13230.6 GAX10542.1 - 0.065 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II YwiC PF14256.6 GAX10542.1 - 0.096 13.0 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 YwiC-like protein DSPc PF00782.20 GAX10542.1 - 0.13 12.1 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF3399 PF11879.8 GAX10543.1 - 0.018 15.4 1.4 4.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) ABC1 PF03109.16 GAX10544.1 - 9.3e-29 100.0 0.0 1.9e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GAX10544.1 - 0.081 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain HSF_DNA-bind PF00447.17 GAX10545.1 - 3.3e-17 62.9 0.2 5.8e-17 62.1 0.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 GAX10545.1 - 0.0066 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Ets-domain MFS_1 PF07690.16 GAX10546.1 - 3.6e-30 105.1 41.0 1e-23 83.8 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAX10547.1 - 8.1e-22 77.6 25.5 1e-21 77.2 23.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX10547.1 - 0.00066 18.7 11.6 0.0025 16.8 11.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Haemadin PF09065.10 GAX10547.1 - 0.12 12.2 0.6 0.24 11.2 0.6 1.5 1 0 0 1 1 1 0 Haemadin DUF1146 PF06612.11 GAX10547.1 - 5.4 7.1 11.0 3.5 7.8 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) TPX2_importin PF12214.8 GAX10548.1 - 1.8e-13 51.1 6.9 6.6e-08 32.9 0.2 3.1 3 0 0 3 3 3 2 Cell cycle regulated microtubule associated protein HATPase_c PF02518.26 GAX10549.1 - 1.9e-27 96.0 0.0 3.4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX10549.1 - 1.5e-22 79.9 0.0 1.6e-21 76.5 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAX10549.1 - 3.1e-21 75.2 0.1 6.9e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 GAX10549.1 - 0.074 13.1 0.1 8.2 6.5 0.0 2.6 2 0 0 2 2 2 0 PAS fold HATPase_c_3 PF13589.6 GAX10549.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 GAX10550.1 - 2.8e-26 91.2 17.2 2.2e-06 28.3 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Bromodomain PF00439.25 GAX10550.1 - 2.7e-25 88.3 0.6 3.5e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Ge1_WD40 PF16529.5 GAX10550.1 - 0.07 12.1 0.0 12 4.7 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Biotin_lipoyl PF00364.22 GAX10551.1 - 3.1e-13 49.3 4.0 3.1e-13 49.3 4.0 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAX10551.1 - 0.00031 20.5 2.8 0.023 14.5 0.7 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 GAX10551.1 - 0.0092 15.9 3.1 0.01 15.7 0.7 1.9 1 1 1 2 2 2 1 Glycine cleavage H-protein RGCC PF15151.6 GAX10551.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Response gene to complement 32 protein family HlyD_D23 PF16576.5 GAX10551.1 - 0.013 14.7 1.0 0.67 9.1 0.1 2.1 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 GAX10551.1 - 0.017 15.8 3.2 0.16 12.7 3.2 2.2 1 1 0 1 1 1 0 HlyD family secretion protein DnaJ PF00226.31 GAX10556.1 - 4.7e-19 68.3 0.4 9.2e-19 67.3 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 GAX10556.1 - 9.3e-05 22.2 5.7 9.3e-05 22.2 5.7 3.6 3 2 1 4 4 4 2 Transmembrane Fragile-X-F protein DUF4897 PF16238.5 GAX10556.1 - 0.021 14.6 0.2 0.039 13.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) Phage_holin_Dp1 PF16938.5 GAX10556.1 - 0.09 13.0 0.6 1.4 9.2 0.4 2.5 2 0 0 2 2 2 0 Putative phage holin Dp-1 Pes-10 PF07149.11 GAX10557.1 - 7.2 5.6 7.4 11 5.0 7.4 1.2 1 0 0 1 1 1 0 Pes-10 DUF92 PF01940.16 GAX10559.1 - 4e-65 219.5 10.0 4.7e-65 219.3 10.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 NQR2_RnfD_RnfE PF03116.15 GAX10559.1 - 0.013 14.9 2.3 0.013 14.9 2.3 2.1 1 1 0 1 1 1 0 NQR2, RnfD, RnfE family Ribosomal_L28e PF01778.17 GAX10560.1 - 2.9e-35 121.5 0.6 2.9e-35 121.5 0.6 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 GAX10560.1 - 1.7e-29 102.3 22.2 1.7e-29 102.3 22.2 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 GAX10560.1 - 0.0084 15.5 20.2 0.01 15.2 20.2 1.2 1 0 0 1 1 1 1 BUD22 Cwf_Cwc_15 PF04889.12 GAX10560.1 - 3.3 7.4 27.3 5.2 6.7 27.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TLC PF03219.14 GAX10561.1 - 3.3e-16 59.1 17.1 5.8e-10 38.5 9.9 3.1 2 1 0 2 2 2 2 TLC ATP/ADP transporter AAA PF00004.29 GAX10562.1 - 1.3e-69 232.7 0.0 6.7e-41 139.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX10562.1 - 6.3e-13 49.5 0.3 0.00021 21.7 0.1 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 GAX10562.1 - 1e-12 47.7 0.8 2.4e-08 33.7 0.2 2.7 2 0 0 2 2 2 2 AAA+ lid domain IstB_IS21 PF01695.17 GAX10562.1 - 3e-11 43.4 0.0 3e-07 30.3 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 GAX10562.1 - 4.1e-11 43.0 0.0 4.5e-05 23.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX10562.1 - 1.5e-08 34.6 0.0 0.00074 19.3 0.0 3.0 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX10562.1 - 2.7e-08 34.2 1.3 0.00069 19.9 0.2 4.4 2 2 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 GAX10562.1 - 5.3e-07 30.0 0.0 0.0053 17.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 GAX10562.1 - 1.6e-06 28.1 0.0 0.00031 20.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAX10562.1 - 2.1e-06 28.0 0.0 0.0054 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 GAX10562.1 - 3.4e-06 26.7 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 GAX10562.1 - 4.6e-06 26.9 0.0 0.0043 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX10562.1 - 5.9e-05 23.6 0.0 0.015 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 GAX10562.1 - 6.3e-05 22.7 0.0 0.0063 16.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 GAX10562.1 - 0.00015 21.3 0.1 0.2 11.0 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GAX10562.1 - 0.00023 21.1 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain NACHT PF05729.12 GAX10562.1 - 0.00036 20.5 0.3 0.77 9.7 0.0 3.8 2 2 1 4 4 4 1 NACHT domain AAA_3 PF07726.11 GAX10562.1 - 0.00059 19.7 0.0 1.8 8.4 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 GAX10562.1 - 0.00066 19.6 0.0 0.018 14.9 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein ATPase_2 PF01637.18 GAX10562.1 - 0.00088 19.3 0.0 0.055 13.4 0.0 3.0 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea TIP49 PF06068.13 GAX10562.1 - 0.0013 18.0 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Hpr_kinase_C PF07475.12 GAX10562.1 - 0.002 17.7 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain Viral_helicase1 PF01443.18 GAX10562.1 - 0.0047 16.7 0.0 2.9 7.6 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 GAX10562.1 - 0.0068 16.9 0.0 0.23 12.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.13 GAX10562.1 - 0.0077 15.4 0.0 0.65 9.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 GAX10562.1 - 0.011 15.8 0.0 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 GAX10562.1 - 0.011 15.7 0.1 0.066 13.1 0.0 2.2 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 GAX10562.1 - 0.013 14.7 0.3 0.097 11.8 0.0 2.3 2 1 1 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 GAX10562.1 - 0.014 14.7 0.1 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 GAX10562.1 - 0.017 14.6 0.2 0.042 13.3 0.0 1.7 2 0 0 2 2 1 0 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 GAX10562.1 - 0.019 14.7 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 GAX10562.1 - 0.02 15.0 0.0 2.8 8.0 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 GAX10562.1 - 0.021 14.6 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX10562.1 - 0.029 14.1 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 GAX10562.1 - 0.032 14.1 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase PF06745.13 GAX10562.1 - 0.033 13.5 0.0 0.83 8.9 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 GAX10562.1 - 0.072 12.7 0.0 9.9 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 GAX10562.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 GAX10562.1 - 0.089 13.0 0.0 5.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAX10562.1 - 0.14 12.5 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain WASH-7_C PF14746.6 GAX10563.1 - 0.13 12.0 1.4 0.23 11.1 1.4 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DUF1556 PF07590.11 GAX10563.1 - 1.5 9.2 6.3 1.3 9.4 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Methyltransf_25 PF13649.6 GAX10565.1 - 2e-08 34.8 0.1 5e-08 33.6 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10565.1 - 0.00014 22.5 0.1 0.00025 21.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX10565.1 - 0.00024 20.9 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX10565.1 - 0.00025 20.9 0.1 0.00086 19.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 GAX10565.1 - 0.0028 17.2 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NOA36 PF06524.12 GAX10566.1 - 0.13 11.6 3.6 0.28 10.5 3.6 1.5 1 0 0 1 1 1 0 NOA36 protein BTB_2 PF02214.22 GAX10567.1 - 2.2e-17 63.2 0.0 4.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain She9_MDM33 PF05546.11 GAX10567.1 - 0.036 13.9 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family BTB_3 PF16017.5 GAX10567.1 - 0.094 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain KdgT PF03812.13 GAX10568.1 - 0.012 15.0 0.4 0.017 14.4 0.4 1.1 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease Glyco_transf_8 PF01501.20 GAX10568.1 - 0.064 12.8 0.0 14 5.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 8 Sarcoglycan_1 PF04790.13 GAX10569.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein PK PF00224.21 GAX10570.1 - 2.8e-104 348.8 0.0 3.7e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAX10570.1 - 4.4e-32 110.7 0.0 1.1e-31 109.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 GAX10570.1 - 0.025 13.6 0.0 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain WW PF00397.26 GAX10571.1 - 6.5e-06 26.1 3.4 6.5e-06 26.1 3.4 2.0 2 0 0 2 2 2 1 WW domain FapA PF03961.13 GAX10572.1 - 0.52 8.9 7.5 0.041 12.5 2.4 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Pet20 PF08692.10 GAX10572.1 - 1.2 9.9 4.5 8.8 7.1 3.3 3.0 2 1 0 2 2 2 0 Mitochondrial protein Pet20 Sec16 PF12932.7 GAX10572.1 - 4.5 7.9 5.5 20 5.8 1.2 2.9 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region BLOC1_2 PF10046.9 GAX10572.1 - 6.4 7.2 11.3 0.78 10.1 5.3 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CSRNP_N PF16019.5 GAX10573.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus Aldo_ket_red PF00248.21 GAX10575.1 - 2.1e-16 60.0 0.4 1.8e-15 56.9 0.4 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 GAX10576.1 - 0.0016 18.2 0.1 0.0038 17.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 GAX10576.1 - 0.0074 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 RL domain STAS_2 PF13466.6 GAX10576.1 - 0.12 12.8 0.2 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 STAS domain zf-C2H2_4 PF13894.6 GAX10577.1 - 0.025 15.4 1.4 0.025 15.4 1.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 GAX10577.1 - 0.028 14.8 0.3 0.13 12.7 0.3 2.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type UIM PF02809.20 GAX10578.1 - 0.004 17.0 3.4 0.011 15.6 3.4 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif CPBP PF02517.16 GAX10579.1 - 0.095 13.1 4.0 1.5 9.3 0.1 2.6 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease UPF0016 PF01169.19 GAX10579.1 - 1.2 9.6 8.4 1.9 8.9 0.8 3.1 2 1 1 3 3 3 0 Uncharacterized protein family UPF0016 SAP PF02037.27 GAX10580.1 - 6.2e-11 41.8 0.8 1.4e-10 40.6 0.8 1.7 1 0 0 1 1 1 1 SAP domain NusG PF02357.19 GAX10580.1 - 0.007 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Transcription termination factor nusG Telomere_Sde2_2 PF13297.6 GAX10580.1 - 0.01 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Telomere stability C-terminal ApoL PF05461.11 GAX10580.1 - 0.53 9.6 2.6 0.91 8.8 2.6 1.3 1 0 0 1 1 1 0 Apolipoprotein L Semialdhyde_dhC PF02774.18 GAX10582.1 - 3.8e-47 160.8 0.0 6.2e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GAX10582.1 - 5.8e-28 97.8 0.1 1e-27 97.0 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAX10582.1 - 2.6e-05 24.7 0.3 0.00011 22.7 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Gp_dh_C PF02800.20 GAX10582.1 - 0.028 14.0 0.2 0.16 11.6 0.1 2.2 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.20 GAX10582.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TIP49 PF06068.13 GAX10583.1 - 3.3e-144 480.4 0.0 4.3e-144 480.0 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAX10583.1 - 6.5e-22 77.4 0.8 1.5e-21 76.3 0.8 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAX10583.1 - 1.1e-08 35.5 0.9 8.9e-06 26.2 0.0 3.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX10583.1 - 1.3e-06 28.3 0.1 0.00038 20.2 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX10583.1 - 0.00022 21.6 2.4 0.00034 21.0 0.7 2.3 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 GAX10583.1 - 0.00025 20.5 0.3 0.056 12.8 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX10583.1 - 0.00032 20.7 0.3 0.47 10.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAX10583.1 - 0.0014 18.9 0.1 0.0031 17.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAX10583.1 - 0.0015 18.2 0.0 1.6 8.4 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain DnaB_C PF03796.15 GAX10583.1 - 0.0022 17.4 1.4 0.0024 17.2 0.1 1.7 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAX10583.1 - 0.0032 17.7 0.1 0.42 10.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Nexin_C PF08628.12 GAX10583.1 - 0.017 15.7 0.0 0.044 14.4 0.0 1.7 1 0 0 1 1 1 0 Sorting nexin C terminal AAA_33 PF13671.6 GAX10583.1 - 0.018 15.2 0.0 0.058 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAX10583.1 - 0.02 15.3 0.1 0.13 12.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAX10583.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAX10583.1 - 0.05 12.9 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin tRNA-synt_2 PF00152.20 GAX10584.1 - 1.9e-73 247.3 0.0 2.6e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX10584.1 - 2.2e-05 24.3 0.0 0.00021 21.2 0.0 2.5 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX10584.1 - 3.8e-05 23.3 0.2 0.026 14.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FAD_binding_1 PF00667.20 GAX10585.1 - 5.7e-24 84.9 0.0 1e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX10585.1 - 1e-18 67.9 0.0 2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAX10585.1 - 9.4e-11 42.3 0.0 2.8e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DNA_topoisoIV PF00521.20 GAX10586.1 - 3.6e-130 434.7 0.6 3.1e-129 431.6 0.0 2.2 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAX10586.1 - 9.5e-37 126.1 5.2 1.2e-24 87.0 1.7 3.0 1 1 1 2 2 2 2 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAX10586.1 - 1.8e-22 79.6 1.4 5.2e-22 78.2 1.4 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GAX10586.1 - 1.2e-11 45.1 0.0 3e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAX10586.1 - 7.5e-08 32.5 0.0 3.8e-07 30.3 0.0 2.3 1 0 0 1 1 1 1 Toprim domain CHCH PF06747.13 GAX10587.1 - 0.0062 16.6 12.2 0.0088 16.2 12.2 1.2 1 0 0 1 1 1 1 CHCH domain Na_K-ATPase PF00287.18 GAX10587.1 - 0.12 11.5 3.4 0.16 11.1 3.4 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain CX9C PF16860.5 GAX10587.1 - 0.82 9.7 8.0 1.2 9.2 8.0 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2985 PF11204.8 GAX10588.1 - 1.7e-10 40.9 4.9 2.1e-10 40.6 2.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF2231 PF09990.9 GAX10588.1 - 3.9 7.9 6.7 0.38 11.2 0.3 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) Ubiq_cyt_C_chap PF03981.12 GAX10590.1 - 8.1e-09 35.7 0.5 1.3e-08 35.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 GAX10590.1 - 4.6e-06 26.6 2.2 1e-05 25.5 2.2 1.6 1 0 0 1 1 1 1 WW domain Zn-ribbon_8 PF09723.10 GAX10591.1 - 5.2e-05 23.3 0.7 8.8e-05 22.5 0.7 1.3 1 0 0 1 1 1 1 Zinc ribbon domain A2L_zn_ribbon PF08792.10 GAX10591.1 - 0.00061 19.4 0.6 0.0072 16.0 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 GAX10591.1 - 0.0015 18.0 4.7 0.019 14.5 0.3 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 GAX10591.1 - 0.0028 17.0 4.5 0.62 9.6 0.3 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-trcl PF13451.6 GAX10591.1 - 0.0077 16.1 1.7 0.45 10.5 2.3 2.4 1 1 1 2 2 2 1 Probable zinc-ribbon domain zf-Mss51 PF13824.6 GAX10591.1 - 0.0092 16.1 4.9 0.19 11.8 0.2 2.2 1 1 1 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 OrfB_Zn_ribbon PF07282.11 GAX10591.1 - 0.011 15.7 0.3 0.023 14.6 0.3 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.19 GAX10591.1 - 0.017 15.1 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mu-like_Com PF10122.9 GAX10591.1 - 0.05 13.1 0.2 0.086 12.3 0.2 1.3 1 0 0 1 1 1 0 Mu-like prophage protein Com Nudix_N_2 PF14803.6 GAX10591.1 - 0.054 13.4 0.7 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal DZR PF12773.7 GAX10591.1 - 0.059 13.4 0.7 0.14 12.2 0.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 GAX10591.1 - 0.087 12.6 0.9 4.6 7.0 2.4 2.1 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-H2C2_2 PF13465.6 GAX10591.1 - 0.13 12.8 5.2 1.2 9.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain TFIIS_C PF01096.18 GAX10591.1 - 0.13 12.1 1.6 2.9 7.8 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Rubredoxin PF00301.20 GAX10591.1 - 0.14 12.2 8.7 42 4.3 8.7 2.5 1 1 0 1 1 1 0 Rubredoxin Rubredoxin_2 PF18073.1 GAX10591.1 - 0.27 11.0 0.5 0.27 11.0 0.5 2.9 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-HIT PF04438.16 GAX10591.1 - 0.47 10.4 4.1 4.1 7.4 0.9 2.2 2 0 0 2 2 2 0 HIT zinc finger zf_UBZ PF18439.1 GAX10591.1 - 0.8 9.3 2.5 14 5.4 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 GAX10591.1 - 0.96 9.6 6.2 0.65 10.1 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C2H2 PF00096.26 GAX10591.1 - 2.2 8.9 8.9 0.31 11.6 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Transket_pyr PF02779.24 GAX10592.1 - 4.2e-44 150.4 0.2 5.6e-44 149.9 0.2 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX10592.1 - 1.3e-33 115.5 0.0 2.3e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain bZIP_1 PF00170.21 GAX10593.1 - 0.002 18.2 15.5 0.013 15.6 15.5 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX10593.1 - 0.039 14.1 8.0 0.039 14.1 8.0 2.6 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 GAX10593.1 - 0.73 10.4 15.9 0.22 12.1 12.2 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor SlyX PF04102.12 GAX10593.1 - 1.4 9.6 8.1 6.7 7.4 8.1 2.3 1 1 0 1 1 1 0 SlyX GvpL_GvpF PF06386.11 GAX10593.1 - 1.7 8.5 8.0 2.4 8.1 8.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4140 PF13600.6 GAX10593.1 - 2.4 8.7 7.8 7.7 7.0 7.8 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HNOBA PF07701.14 GAX10593.1 - 2.7 7.4 9.0 0.27 10.6 4.1 1.8 1 1 1 2 2 2 0 Heme NO binding associated MTD PF01993.18 GAX10594.1 - 0.23 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase RVT_2 PF07727.14 GAX10596.1 - 8.9e-18 64.8 0.0 2.2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3040 PF11239.8 GAX10598.1 - 0.038 14.3 0.6 0.073 13.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) TnsD PF15978.5 GAX10598.1 - 0.087 11.8 0.1 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Tn7-like transposition protein D HAD_2 PF13419.6 GAX10599.1 - 1.4e-18 67.6 0.0 2.8e-18 66.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX10599.1 - 1.3e-09 38.7 0.0 3.4e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX10599.1 - 1.3e-07 31.5 0.0 3.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GAX10599.1 - 0.00052 20.5 0.0 0.00096 19.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NPA PF16469.5 GAX10599.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Phage_int_SAM_5 PF13102.6 GAX10599.1 - 0.16 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain ClpS PF02617.17 GAX10600.1 - 4.1e-08 32.9 0.6 7.8e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Nab2 PF11517.8 GAX10600.1 - 0.14 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Kelch_5 PF13854.6 GAX10601.1 - 1.5e-30 104.6 0.4 6e-05 22.9 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 GAX10601.1 - 4.7e-28 97.0 10.3 9.1e-05 22.4 0.5 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAX10601.1 - 4.5e-20 71.4 19.5 6e-06 26.4 0.1 7.5 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GAX10601.1 - 1.1e-17 63.2 16.9 1.2e-05 25.1 0.2 6.9 5 1 1 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAX10601.1 - 4e-17 61.8 8.1 0.016 15.5 0.2 5.8 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GAX10601.1 - 8.6e-13 47.7 11.9 2.1e-05 24.0 0.2 5.5 5 1 0 5 5 5 4 Kelch motif zf-C4H2 PF10146.9 GAX10601.1 - 0.12 12.6 6.0 0.18 12.1 6.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Ank_2 PF12796.7 GAX10604.1 - 6.3e-28 97.2 2.2 1.3e-09 38.5 0.0 3.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX10604.1 - 1.9e-25 88.9 0.1 7.5e-10 39.2 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX10604.1 - 7.1e-20 70.5 0.8 0.0013 19.1 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 GAX10604.1 - 2.7e-19 69.0 2.7 1.3e-07 31.7 0.3 6.3 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX10604.1 - 2.3e-16 58.2 0.0 0.018 15.5 0.0 7.1 6 1 0 6 6 6 4 Ankyrin repeat mTERF PF02536.14 GAX10604.1 - 2.7e-07 29.8 0.0 4.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 mTERF LPD39 PF18858.1 GAX10604.1 - 0.21 11.7 8.1 0.71 9.9 0.4 2.6 2 1 1 3 3 3 0 Large polyvalent protein associated domain 39 Na_H_Exchanger PF00999.21 GAX10605.1 - 1.3e-46 159.1 26.3 6e-38 130.6 17.3 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Cation_ATPase_C PF00689.21 GAX10606.1 - 8.4e-08 32.1 7.1 6.7e-07 29.2 0.5 3.6 3 1 1 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAX10606.1 - 0.0085 15.6 0.0 0.0085 15.6 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase PI-PLC-X PF00388.19 GAX10606.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain EMP70 PF02990.16 GAX10606.1 - 0.23 10.1 2.4 0.68 8.5 0.3 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 TraG_N PF07916.11 GAX10606.1 - 2.3 6.9 5.5 3.2 6.5 0.0 2.5 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Peptidase_M43 PF05572.13 GAX10607.1 - 1.1e-12 48.1 0.0 1.7e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX10607.1 - 0.00065 20.2 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX10607.1 - 0.0021 17.7 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX10607.1 - 0.0082 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX10607.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 GAX10607.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 GAX10607.1 - 0.036 13.3 0.1 0.06 12.5 0.1 1.3 1 0 0 1 1 1 0 Met-zincin UcrQ PF02939.16 GAX10608.1 - 0.0013 18.7 0.2 0.0019 18.1 0.2 1.3 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 GAX10608.1 - 0.0025 18.1 0.1 0.0032 17.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 FA_hydroxylase PF04116.13 GAX10609.1 - 1.4e-16 61.1 17.3 1.4e-16 61.1 17.3 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Cytotoxic PF09000.10 GAX10609.1 - 0.065 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Cytotoxic HemY_N PF07219.13 GAX10609.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus ORC2 PF04084.14 GAX10610.1 - 6.7e-50 169.9 0.1 1e-49 169.3 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MBD PF01429.19 GAX10610.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyl-CpG binding domain Spc7_N PF15402.6 GAX10611.1 - 0.74 8.0 7.6 0.94 7.6 7.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Prenyltrans PF00432.21 GAX10613.1 - 2.2e-55 184.1 15.8 1.3e-11 44.0 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAX10613.1 - 0.00034 19.8 0.0 0.0014 17.8 0.0 2.0 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain ketoacyl-synt PF00109.26 GAX10614.1 - 4.4e-55 187.0 1.0 7.4e-55 186.3 1.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAX10614.1 - 2.9e-32 111.2 1.2 9.4e-32 109.5 1.6 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAX10614.1 - 2.1e-05 24.0 1.8 3.7e-05 23.2 1.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAX10614.1 - 0.039 13.8 3.0 1.5 8.7 0.4 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CitMHS PF03600.16 GAX10615.1 - 2.2e-30 105.9 12.2 4e-30 105.0 12.2 1.4 1 1 0 1 1 1 1 Citrate transporter CBS PF00571.28 GAX10615.1 - 8.3e-10 39.0 0.3 0.00028 21.3 0.0 2.9 2 0 0 2 2 2 2 CBS domain PseudoU_synth_2 PF00849.22 GAX10617.1 - 4.1e-25 88.7 0.0 6.2e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase CPSase_L_D2 PF02786.17 GAX10618.1 - 2.7e-105 350.5 0.7 9.7e-79 263.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAX10618.1 - 4.2e-49 165.6 0.0 9.1e-49 164.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAX10618.1 - 2.8e-42 144.6 0.0 1.9e-41 141.9 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 GAX10618.1 - 2.4e-38 131.2 0.0 5.7e-38 130.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 GAX10618.1 - 2.9e-14 53.0 0.5 3.2e-08 33.3 0.2 3.0 3 0 0 3 3 3 2 ATP-grasp domain MGS PF02142.22 GAX10618.1 - 1.6e-13 50.6 0.0 3.7e-12 46.3 0.0 3.2 3 0 0 3 3 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 GAX10618.1 - 2.9e-12 46.6 0.4 3.9e-05 23.3 0.2 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAX10618.1 - 1.6e-11 44.1 0.1 3.9e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 GAX10618.1 - 1.9e-05 24.5 0.1 0.00093 19.0 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_5 PF13549.6 GAX10618.1 - 0.00023 20.7 0.1 0.23 10.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 GAX10618.1 - 0.004 16.8 0.0 0.83 9.2 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 GAX10618.1 - 0.013 15.6 0.2 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 ATP-grasp domain GARS_A PF01071.19 GAX10618.1 - 0.05 13.4 0.6 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-synt_Eps PF04627.13 GAX10619.1 - 1.1e-14 54.2 1.5 1.3e-14 53.9 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Exo_endo_phos PF03372.23 GAX10620.1 - 1.8e-06 27.6 0.0 5.9e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_16 PF10294.9 GAX10621.1 - 2.8e-12 46.7 0.0 7.6e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAX10621.1 - 3.4e-05 24.5 0.0 8.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10621.1 - 0.00012 22.8 0.0 0.00027 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX10621.1 - 0.00077 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX10621.1 - 0.037 14.7 0.0 0.098 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAX10621.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain VASt PF16016.5 GAX10622.1 - 6e-22 78.7 2.2 1.7e-21 77.3 2.2 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Tape_meas_lam_C PF09718.10 GAX10622.1 - 0.11 12.6 0.1 6.1 7.0 0.0 2.8 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) PQQ_2 PF13360.6 GAX10623.1 - 0.0018 17.9 0.0 0.96 9.0 0.1 2.3 2 0 0 2 2 2 2 PQQ-like domain Nup_retrotrp_bd PF10599.9 GAX10623.1 - 0.027 15.1 0.9 0.093 13.4 0.9 1.9 1 0 0 1 1 1 0 Retro-transposon transporting motif Arylesterase PF01731.20 GAX10623.1 - 0.077 13.2 0.3 44 4.4 0.0 3.4 3 0 0 3 3 3 0 Arylesterase Peptidase_S8 PF00082.22 GAX10625.1 - 1.7e-74 250.8 0.3 2.7e-74 250.1 0.3 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 GAX10625.1 - 5.1e-50 169.6 0.0 7.9e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II DCR PF14047.6 GAX10625.1 - 0.15 12.3 0.0 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 Dppa2/4 conserved region Rieske_3 PF18465.1 GAX10625.1 - 0.17 12.2 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Rieske 3Fe-4S Peptidase_S8 PF00082.22 GAX10626.1 - 1.7e-25 89.9 5.8 3.1e-25 89.1 5.8 1.3 1 1 0 1 1 1 1 Subtilase family Toxin_12 PF07740.12 GAX10626.1 - 0.044 14.5 3.1 0.044 14.5 3.1 2.4 2 0 0 2 2 2 0 Ion channel inhibitory toxin Conotoxin_I2 PF17557.2 GAX10626.1 - 3 8.0 16.7 8.1 6.6 6.4 2.7 2 0 0 2 2 2 0 I2-superfamily conotoxins Toxin_18 PF08087.11 GAX10626.1 - 5.6 7.0 9.5 2.5 8.2 1.6 2.8 2 0 0 2 2 2 0 Conotoxin O-superfamily UPF0506 PF11703.8 GAX10626.1 - 8.9 6.8 21.6 11 6.5 3.7 2.8 1 1 1 2 2 2 0 UPF0506 FtsL PF04999.13 GAX10627.1 - 0.022 14.7 3.8 4.7 7.3 0.0 2.6 2 1 0 2 2 2 0 Cell division protein FtsL TRAPPC-Trs85 PF12739.7 GAX10628.1 - 1.4e-59 202.2 11.5 7.4e-59 199.7 9.6 2.6 2 1 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 GAX10628.1 - 0.0058 14.1 0.0 0.011 13.2 0.0 1.3 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNAP PF14938.6 GAX10628.1 - 0.026 14.0 6.9 0.039 13.4 1.0 2.5 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP Nucleopor_Nup85 PF07575.13 GAX10629.1 - 1.2e-14 53.8 0.1 5.3e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 Nup85 Nucleoporin Asp_Arg_Hydrox PF05118.15 GAX10630.1 - 9.7e-43 145.7 1.3 1.5e-42 145.1 1.3 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Peptidase_S8 PF00082.22 GAX10631.1 - 9.4e-31 107.2 12.4 1.9e-30 106.2 12.4 1.4 1 0 0 1 1 1 1 Subtilase family PT PF04886.12 GAX10631.1 - 7.6e-05 22.2 74.1 1.3 8.7 20.8 5.5 1 1 2 3 3 3 2 PT repeat Inhibitor_I9 PF05922.16 GAX10631.1 - 0.0013 19.3 0.1 0.0025 18.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Adhesin_P1_N PF18652.1 GAX10631.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain S4 PF01479.25 GAX10632.1 - 2.2e-13 49.7 0.8 3.9e-13 48.9 0.8 1.4 1 0 0 1 1 1 1 S4 domain DUF1648 PF07853.11 GAX10633.1 - 0.05 13.3 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Fasciclin PF02469.22 GAX10634.1 - 6.2e-26 91.1 0.0 2.2e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain BrkDBD PF09607.10 GAX10635.1 - 0.12 12.1 0.6 0.27 11.1 0.6 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain TIR-like PF10137.9 GAX10636.1 - 0.0089 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain Glyco_transf_25 PF01755.17 GAX10636.1 - 0.2 11.5 0.4 0.28 11.0 0.4 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Fasciclin PF02469.22 GAX10637.1 - 7.8e-15 55.2 0.1 5.3e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain NodZ PF05830.11 GAX10639.1 - 1.4e-06 27.4 0.0 3.8e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Nodulation protein Z (NodZ) PIG-P PF08510.12 GAX10640.1 - 0.081 12.8 4.0 0.17 11.8 4.0 1.5 1 0 0 1 1 1 0 PIG-P TB2_DP1_HVA22 PF03134.19 GAX10641.1 - 0.43 10.6 16.0 0.036 14.0 2.3 3.2 3 0 0 3 3 3 0 TB2/DP1, HVA22 family PI3_PI4_kinase PF00454.27 GAX10642.1 - 1.8e-30 106.6 0.0 8.9e-28 97.8 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 GAX10642.1 - 0.00035 21.0 0.0 0.00094 19.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4135 PF13575.6 GAX10642.1 - 0.038 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) U3_snoRNA_assoc PF08297.11 GAX10642.1 - 0.49 11.1 2.6 1.6 9.5 2.6 1.9 1 1 0 1 1 1 0 U3 snoRNA associated TMF_DNA_bd PF12329.8 GAX10643.1 - 0.0048 16.9 0.4 0.0048 16.9 0.4 4.2 1 1 3 4 4 4 1 TATA element modulatory factor 1 DNA binding Exonuc_VII_L PF02601.15 GAX10643.1 - 0.007 16.0 6.8 0.0077 15.8 6.8 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit RPW8 PF05659.11 GAX10643.1 - 0.015 15.0 4.6 0.022 14.4 4.0 1.6 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Yop-YscD_cpl PF16697.5 GAX10643.1 - 0.051 13.9 0.5 0.12 12.7 0.3 1.8 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Cytochrom_C552 PF02335.15 GAX10643.1 - 0.62 8.9 11.0 0.086 11.7 4.4 2.0 1 1 1 2 2 2 0 Cytochrome c552 Leu_zip PF15294.6 GAX10643.1 - 0.64 9.5 20.8 0.77 9.2 3.7 2.1 1 1 1 2 2 2 0 Leucine zipper FAM76 PF16046.5 GAX10643.1 - 2 7.7 18.8 0.098 12.0 10.3 2.0 1 1 1 2 2 2 0 FAM76 protein DUF4407 PF14362.6 GAX10643.1 - 4.5 6.5 13.1 6.7 6.0 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIN_8 PF18476.1 GAX10644.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 PIN like domain Chalcone_3 PF16036.5 GAX10644.1 - 0.054 13.6 0.5 9.5 6.3 0.0 3.1 3 0 0 3 3 3 0 Chalcone isomerase-like DUF4558 PF15104.6 GAX10644.1 - 0.086 12.9 0.2 0.27 11.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) DUF745 PF05335.13 GAX10644.1 - 0.14 11.9 0.2 0.27 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-C3H2C3 PF17122.5 GAX10644.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger HEAT PF02985.22 GAX10645.1 - 7.9e-31 103.5 23.6 0.0022 18.1 0.0 12.0 12 0 0 12 12 12 8 HEAT repeat HEAT_2 PF13646.6 GAX10645.1 - 4.3e-28 97.5 9.9 4.8e-05 23.7 0.0 7.3 4 2 3 7 7 7 6 HEAT repeats Cnd1 PF12717.7 GAX10645.1 - 7.2e-15 55.4 0.4 0.01 15.9 0.0 5.4 3 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX10645.1 - 3.8e-11 43.2 14.0 6.1e-05 23.4 0.0 8.4 8 0 0 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.20 GAX10645.1 - 1.2e-07 30.7 0.0 0.033 12.7 0.0 4.2 2 1 2 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 GAX10645.1 - 0.00062 19.4 0.0 0.36 10.4 0.0 3.6 3 1 1 4 4 4 2 CLASP N terminal Gcn1_N PF12074.8 GAX10645.1 - 0.0057 16.0 1.5 3.1 7.0 0.0 3.7 5 0 0 5 5 5 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal V-ATPase_H_N PF03224.14 GAX10645.1 - 0.013 14.8 0.1 3 7.0 0.0 2.5 2 1 0 2 2 2 0 V-ATPase subunit H PIF1 PF05970.14 GAX10645.1 - 0.058 12.6 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Cohesin_HEAT PF12765.7 GAX10645.1 - 0.78 10.1 6.5 31 5.0 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.16 GAX10645.1 - 4.8 8.2 12.9 31 5.6 0.1 6.0 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Myosin_head PF00063.21 GAX10647.1 - 1.9e-181 604.8 0.4 9.5e-181 602.4 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_22 PF13401.6 GAX10647.1 - 0.007 16.6 0.7 0.075 13.3 0.0 3.2 4 0 0 4 4 4 1 AAA domain Myosin_N PF02736.19 GAX10647.1 - 0.016 15.0 0.5 0.18 11.7 0.0 2.7 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 GAX10647.1 - 0.057 13.8 0.0 0.057 13.8 0.0 3.6 2 1 0 2 2 2 0 AAA ATPase domain IQ PF00612.27 GAX10647.1 - 0.72 9.8 30.5 0.64 10.0 1.1 5.7 5 0 0 5 5 5 0 IQ calmodulin-binding motif ABC_tran PF00005.27 GAX10647.1 - 3.9 8.0 0.0 3.9 8.0 0.0 3.2 3 1 1 4 4 4 0 ABC transporter Lig_chan PF00060.26 GAX10648.1 - 0.019 14.8 0.8 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel DUF4383 PF14325.6 GAX10648.1 - 0.083 13.2 11.6 0.043 14.1 8.8 1.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4383) DUF3671 PF12420.8 GAX10648.1 - 0.57 10.3 4.1 7.8 6.6 4.1 2.2 1 1 0 1 1 1 0 Protein of unknown function DSPc PF00782.20 GAX10649.1 - 7.4e-21 74.3 0.0 9.8e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAX10649.1 - 1.7e-06 28.2 0.0 2.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAX10649.1 - 0.0033 17.0 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.25 GAX10650.1 - 5.1e-58 196.5 0.0 8e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10650.1 - 3.9e-41 141.1 0.0 5.9e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 GAX10650.1 - 1.2e-12 47.8 0.3 2.5e-12 46.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 GAX10650.1 - 0.0012 17.7 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX10650.1 - 0.032 14.1 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 GAX10651.1 - 1.1e-09 37.7 38.0 1.1e-09 37.7 38.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAX10651.1 - 7.8e-06 25.7 5.1 7.8e-06 25.7 5.1 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2530 PF10745.9 GAX10651.1 - 1.8 8.9 6.8 1 9.6 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) CxC6 PF18721.1 GAX10652.1 - 0.003 17.8 5.1 0.0065 16.7 5.1 1.5 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases E3_UbLigase_RBR PF18091.1 GAX10652.1 - 0.061 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain GST_C PF00043.25 GAX10655.1 - 1.3e-08 35.0 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX10655.1 - 2.1e-08 34.3 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX10655.1 - 3.8e-06 26.8 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAX10655.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAX10655.1 - 0.057 13.8 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain XPG_I PF00867.18 GAX10656.1 - 6.8e-12 45.6 0.0 1.7e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 GAX10656.1 - 0.0008 19.0 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 GAX10656.1 - 0.0012 19.3 0.0 0.33 11.5 0.0 2.6 2 0 0 2 2 2 2 XPG N-terminal domain XRN_N PF03159.18 GAX10656.1 - 0.018 14.4 0.3 0.058 12.8 0.1 1.8 1 1 1 2 2 2 0 XRN 5'-3' exonuclease N-terminus Ribosomal_L21e PF01157.18 GAX10657.1 - 8.6e-44 147.5 5.6 1.6e-43 146.6 4.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e HAS-barrel PF09378.10 GAX10657.1 - 0.006 16.7 0.0 0.022 14.9 0.0 2.0 1 1 1 2 2 2 1 HAS barrel domain ZapB PF06005.12 GAX10657.1 - 0.047 14.1 0.6 0.076 13.5 0.6 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF2846 PF11008.8 GAX10657.1 - 0.049 13.7 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Ank_2 PF12796.7 GAX10658.1 - 1.2e-08 35.4 0.1 2.8e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX10658.1 - 4.2e-06 26.7 0.1 0.026 15.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAX10658.1 - 0.00012 22.4 0.6 0.0037 17.6 0.1 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 GAX10658.1 - 0.00014 22.4 0.1 0.0029 18.1 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX10658.1 - 0.0002 21.6 0.1 0.0007 19.8 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) CSN7a_helixI PF18392.1 GAX10658.1 - 0.099 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Methyltransf_4 PF02390.17 GAX10658.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase VASt PF16016.5 GAX10659.1 - 1e-25 91.0 0.2 2.8e-25 89.5 0.1 1.8 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAX10659.1 - 7e-09 35.6 0.0 0.0002 21.2 0.0 2.5 2 0 0 2 2 2 2 GRAM domain COX8 PF02285.15 GAX10659.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII NADH_dh_m_C1 PF15088.6 GAX10659.1 - 0.2 11.3 0.6 2 8.1 0.2 2.7 2 1 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DNA_pol_A_exo1 PF01612.20 GAX10660.1 - 4.2e-08 33.1 0.0 6.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease ARID PF01388.21 GAX10662.1 - 0.079 13.6 0.0 2.8 8.7 0.0 3.2 3 1 0 3 3 3 0 ARID/BRIGHT DNA binding domain Enolase_C PF00113.22 GAX10663.1 - 9.3e-132 438.7 0.0 1.2e-131 438.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAX10663.1 - 7.8e-56 187.8 0.3 1.4e-55 187.0 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAX10663.1 - 4.9e-08 32.8 0.0 8.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAX10663.1 - 3.8e-06 26.2 0.3 3.8e-06 26.2 0.3 1.5 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Peptidase_M3 PF01432.20 GAX10664.1 - 1e-42 147.0 0.1 1.6e-42 146.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 VASt PF16016.5 GAX10665.1 - 4.1e-16 59.7 0.1 5.6e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PPR PF01535.20 GAX10666.1 - 3.1e-41 136.8 21.9 0.00011 22.2 0.0 16.4 17 0 0 17 17 17 7 PPR repeat PPR_3 PF13812.6 GAX10666.1 - 1.2e-38 131.0 0.0 9.3e-11 41.6 0.0 9.2 4 3 3 9 9 9 6 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAX10666.1 - 1.5e-37 127.5 18.0 1.1e-06 28.7 0.0 13.0 7 4 7 14 14 14 10 PPR repeat family PPR_long PF17177.4 GAX10666.1 - 1.5e-27 96.4 4.2 5.9e-11 42.1 0.2 5.3 3 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAX10666.1 - 2e-17 62.6 21.5 9.5e-05 22.0 0.0 10.6 13 0 0 13 13 13 4 PPR repeat Smr PF01713.21 GAX10666.1 - 3.7e-07 30.4 0.1 1.4e-06 28.5 0.1 2.1 1 0 0 1 1 1 1 Smr domain TPR_5 PF12688.7 GAX10666.1 - 1.4e-06 28.5 0.8 9.5e-05 22.6 0.0 3.8 3 1 1 4 4 4 1 Tetratrico peptide repeat TPR_14 PF13428.6 GAX10666.1 - 4.8e-06 26.9 16.8 7.3 7.7 0.2 10.0 11 2 2 13 13 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX10666.1 - 0.00042 20.1 6.1 45 4.4 0.0 7.7 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX10666.1 - 0.00055 20.2 8.5 0.27 11.6 0.1 6.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX10666.1 - 0.0011 19.5 11.1 4.4 7.9 0.3 6.8 7 1 2 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10666.1 - 0.0017 18.4 0.4 2.8 8.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ATP13 PF12921.7 GAX10666.1 - 0.0023 17.8 1.2 51 3.8 0.0 6.2 7 1 0 7 7 7 0 Mitochondrial ATPase expression Clathrin PF00637.20 GAX10666.1 - 0.0023 17.8 0.5 17 5.3 0.0 6.1 6 1 0 6 6 6 0 Region in Clathrin and VPS LRR_2 PF07723.13 GAX10666.1 - 0.022 15.4 0.3 55 4.7 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat ANAPC3 PF12895.7 GAX10666.1 - 0.024 14.9 4.6 1.2 9.4 0.3 5.2 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GAX10666.1 - 0.066 13.1 10.1 2.8 7.9 0.3 7.3 11 0 0 11 11 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10666.1 - 0.32 11.7 7.0 11 6.8 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX10666.1 - 1.1 10.0 12.0 16 6.4 0.0 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX10666.1 - 3.5 8.0 11.4 1.3e+02 3.1 0.0 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat Lipocalin_2 PF08212.12 GAX10668.1 - 2.7e-20 72.8 0.0 3.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain XH PF03469.14 GAX10668.1 - 0.028 14.3 0.4 0.32 10.9 0.0 2.3 3 0 0 3 3 3 0 XH domain DUF308 PF03729.13 GAX10669.1 - 4.8e-09 36.4 10.9 7.3e-05 23.0 0.9 3.3 2 1 1 3 3 3 2 Short repeat of unknown function (DUF308) DUF3098 PF11297.8 GAX10669.1 - 0.071 12.7 0.2 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) PAP_fibrillin PF04755.12 GAX10670.1 - 4.7e-07 29.9 0.3 3.7e-06 27.0 0.3 2.1 1 1 0 1 1 1 1 PAP_fibrillin ParE_toxin PF05016.15 GAX10670.1 - 0.069 13.8 0.0 0.28 11.8 0.0 2.0 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE Linker_histone PF00538.19 GAX10671.1 - 7.3e-14 51.9 0.4 7.3e-14 51.9 0.4 2.0 1 1 1 2 2 2 1 linker histone H1 and H5 family Recombinase PF07508.13 GAX10671.1 - 0.39 11.1 7.6 1.2 9.6 7.5 1.9 1 1 0 1 1 1 0 Recombinase vMSA PF00695.19 GAX10671.1 - 5.7 5.9 5.3 0.82 8.7 0.0 1.9 1 1 1 2 2 2 0 Major surface antigen from hepadnavirus Histone PF00125.24 GAX10672.1 - 2.8e-19 69.8 0.4 3.6e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX10672.1 - 0.00095 19.4 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAX10672.1 - 0.0039 17.6 0.0 0.0068 16.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 GAX10672.1 - 0.0062 16.6 0.1 0.0069 16.4 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein Bt_P21 PF05560.11 GAX10672.1 - 0.046 13.3 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Adap_comp_sub PF00928.21 GAX10673.1 - 1.7e-90 303.0 0.0 2e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 GAX10673.1 - 0.046 13.1 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.20 GAX10673.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Na_H_Exchanger PF00999.21 GAX10674.1 - 2.7e-60 204.2 47.8 4.7e-60 203.4 47.8 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 GAX10674.1 - 7.9e-19 68.0 0.1 2.1e-18 66.7 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain AdoHcyase_NAD PF00670.21 GAX10674.1 - 0.0087 16.1 0.2 0.017 15.2 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pirin PF02678.16 GAX10675.1 - 2e-32 111.3 0.7 9.5e-32 109.2 0.5 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 GAX10675.1 - 6.7e-24 84.3 0.0 4.2e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain ELMO_CED12 PF04727.13 GAX10676.1 - 0.15 12.2 2.2 0.49 10.5 0.8 2.1 1 1 1 2 2 2 0 ELMO/CED-12 family Histone PF00125.24 GAX10678.1 - 6.9e-54 181.7 1.0 7.7e-54 181.6 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GAX10678.1 - 0.00011 22.7 1.1 0.00014 22.5 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GAX10678.1 - 0.00072 19.6 0.3 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX10678.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAX10678.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAX10678.1 - 0.045 13.8 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 GAX10680.1 - 2.9e-62 210.4 0.0 4.6e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10680.1 - 2.1e-28 99.3 0.0 3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX10680.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 GAX10680.1 - 0.038 14.7 0.2 0.038 14.7 0.2 2.3 2 1 0 2 2 2 0 Protein kinase C terminal domain APH PF01636.23 GAX10680.1 - 0.055 13.4 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family PRIMA1 PF16101.5 GAX10680.1 - 9.6 6.3 6.9 22 5.1 6.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FAD-oxidase_C PF02913.19 GAX10681.1 - 1.6e-46 158.9 0.0 2.1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAX10681.1 - 4.3e-32 110.7 0.6 1.6e-31 108.9 0.2 2.1 3 0 0 3 3 3 1 FAD binding domain Complex1_LYR PF05347.15 GAX10682.1 - 0.003 17.6 0.4 0.057 13.5 0.1 2.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Lipocalin_2 PF08212.12 GAX10683.1 - 6.2e-05 22.9 0.0 0.0094 15.9 0.0 2.3 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin_2 PF08212.12 GAX10684.1 - 0.033 14.1 0.2 0.084 12.8 0.0 1.8 2 0 0 2 2 2 0 Lipocalin-like domain SLBB PF10531.9 GAX10684.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 SLBB domain DUF775 PF05603.12 GAX10685.1 - 2.5 7.6 4.9 0.32 10.5 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) WD40 PF00400.32 GAX10687.1 - 4.3e-47 157.1 28.2 3.3e-06 27.7 0.1 11.7 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp13 PF08625.11 GAX10687.1 - 2.3e-34 118.3 0.2 3.7e-34 117.6 0.2 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 GAX10687.1 - 2.1e-14 53.6 6.7 0.018 15.4 0.0 6.9 5 2 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX10687.1 - 2.1e-06 27.3 0.0 0.69 9.2 0.0 5.1 4 1 2 6 6 6 2 WD40-like domain Nup160 PF11715.8 GAX10687.1 - 0.00036 19.3 8.8 0.29 9.7 0.0 5.8 6 2 2 8 8 8 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX10687.1 - 0.0083 15.1 0.3 8.4 5.2 0.0 4.5 4 2 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SHMT PF00464.19 GAX10687.1 - 0.081 11.5 0.0 8.4 4.9 0.0 2.6 2 1 1 3 3 3 0 Serine hydroxymethyltransferase Cpn10 PF00166.21 GAX10688.1 - 4.4e-10 39.5 0.0 6.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit BTB_2 PF02214.22 GAX10689.1 - 2.4e-16 59.9 0.0 4.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX10689.1 - 0.00059 19.9 0.0 0.0019 18.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain V-SNARE PF05008.15 GAX10689.1 - 0.019 15.3 1.7 0.03 14.7 1.7 1.3 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Hexokinase_1 PF00349.21 GAX10689.1 - 0.036 14.0 0.3 0.079 12.8 0.0 1.6 2 0 0 2 2 2 0 Hexokinase GTP_EFTU PF00009.27 GAX10690.1 - 3.7e-38 131.0 0.0 6.2e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 GAX10690.1 - 5.8e-25 88.2 4.5 5.8e-25 88.2 4.5 2.2 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 GAX10690.1 - 4.3e-23 81.4 0.0 1.4e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAX10690.1 - 5e-21 74.5 0.0 1.5e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX10690.1 - 5.1e-07 30.0 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAX10690.1 - 8e-06 25.9 0.0 2.2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAX10690.1 - 0.00082 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP-grasp_2 PF08442.10 GAX10691.1 - 1.9e-61 207.2 0.0 2.9e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 GAX10691.1 - 9.8e-23 80.7 0.6 1.5e-22 80.0 0.6 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 GAX10691.1 - 1.3e-06 28.1 0.1 3.2e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAX10691.1 - 0.0072 16.1 0.5 0.077 12.7 0.0 2.3 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 GAX10691.1 - 0.051 13.4 0.2 0.11 12.3 0.2 1.7 1 1 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain FHA PF00498.26 GAX10692.1 - 2.6e-08 34.1 0.0 4.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAX10692.1 - 3.2e-06 27.4 0.0 9.5e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ax_dynein_light PF10211.9 GAX10692.1 - 0.012 15.6 0.8 0.016 15.1 0.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Popeye PF04831.13 GAX10693.1 - 0.14 12.3 4.2 0.17 12.0 4.2 1.1 1 0 0 1 1 1 0 Popeye protein conserved region Pex24p PF06398.11 GAX10693.1 - 2.7 6.9 5.7 3.2 6.6 5.7 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TMEM208_SND2 PF05620.11 GAX10693.1 - 4.1 7.2 7.5 5.3 6.8 7.5 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 MatE PF01554.18 GAX10697.1 - 6.9e-31 107.1 21.9 1.6e-16 60.4 6.6 2.2 2 0 0 2 2 2 2 MatE Sulfate_transp PF00916.20 GAX10698.1 - 8.5e-26 90.6 17.4 1.7e-24 86.3 17.4 2.4 1 1 0 1 1 1 1 Sulfate permease family Pkinase PF00069.25 GAX10699.1 - 6e-70 235.6 0.0 7.8e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10699.1 - 1.2e-33 116.5 0.4 2.4e-33 115.5 0.4 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX10699.1 - 8.5e-07 28.6 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAX10699.1 - 0.00012 21.5 0.1 0.00022 20.6 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX10699.1 - 0.0027 17.7 0.1 0.44 10.4 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX10699.1 - 0.045 12.7 0.2 0.12 11.3 0.2 1.7 1 1 0 1 1 1 0 Haspin like kinase domain DUF1230 PF06799.11 GAX10700.1 - 3.4e-47 160.2 0.1 4.6e-47 159.7 0.1 1.2 1 0 0 1 1 1 1 Conserved in the green lineage and diatoms 27 MBOAT PF03062.19 GAX10700.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family Sec62 PF03839.16 GAX10700.1 - 0.2 11.1 0.2 0.33 10.4 0.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S28 PF05577.12 GAX10701.1 - 8.1e-42 143.5 0.0 2.8e-41 141.8 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 FKBP_C PF00254.28 GAX10701.1 - 8.8e-22 77.2 0.0 1.8e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 GAX10701.1 - 2.3e-05 25.2 0.0 6.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ank_5 PF13857.6 GAX10702.1 - 0.18 12.2 0.3 1.8 9.0 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX10704.1 - 0.028 15.0 0.1 0.064 13.9 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 GAX10706.1 - 2.1e-16 60.0 0.0 3.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX10706.1 - 3.2e-08 33.3 0.0 4.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX10706.1 - 3.6e-07 30.2 0.0 0.00036 20.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAX10706.1 - 7.7e-07 28.8 0.0 6.2e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GAX10706.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAX10706.1 - 0.004 17.2 0.5 0.37 10.8 0.2 2.9 2 1 1 3 3 3 1 Dynamin family SRPRB PF09439.10 GAX10706.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 GAX10706.1 - 0.079 12.6 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Ras family DNA_pol_phi PF04931.13 GAX10706.1 - 0.61 8.1 13.4 0.89 7.6 13.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Band_7 PF01145.25 GAX10707.1 - 2.2e-27 96.2 2.4 3e-27 95.8 2.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAX10707.1 - 0.0033 17.2 0.1 0.0055 16.4 0.1 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family Importin_rep_3 PF18806.1 GAX10708.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat NRho PF16733.5 GAX10708.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Rhomboid N-terminal domain MKT1_N PF12247.8 GAX10710.1 - 0.097 13.0 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Nop14 PF04147.12 GAX10710.1 - 0.35 9.0 5.1 0.56 8.3 5.1 1.4 1 0 0 1 1 1 0 Nop14-like family DUF4817 PF16087.5 GAX10711.1 - 0.17 11.7 0.1 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Macoilin PF09726.9 GAX10712.1 - 4.2 5.8 20.4 5.1 5.5 20.4 1.1 1 0 0 1 1 1 0 Macoilin family WDCP PF15390.6 GAX10712.1 - 6.9 4.9 15.3 8.6 4.6 15.3 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family 6PGD PF00393.19 GAX10714.1 - 7.8e-121 402.9 0.0 9.9e-121 402.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAX10714.1 - 1.7e-44 151.7 0.0 2.9e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 GAX10714.1 - 0.038 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 GAX10714.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TIC20 PF16166.5 GAX10715.1 - 3.3e-17 62.8 0.1 5.9e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like EF-hand_7 PF13499.6 GAX10715.1 - 1.2e-14 54.5 2.3 9.6e-10 38.8 0.5 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX10715.1 - 3.7e-12 44.9 0.2 2e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 GAX10715.1 - 4.4e-11 41.8 1.5 3.9e-07 29.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX10715.1 - 5e-10 38.5 0.3 1.8e-05 24.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAX10715.1 - 1.9e-08 34.0 0.9 5.9e-06 26.0 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 GAX10715.1 - 0.00046 20.5 0.0 0.00089 19.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GAX10715.1 - 0.0036 17.6 0.0 0.0069 16.7 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region QCR10 PF09796.9 GAX10715.1 - 0.023 14.8 4.4 0.12 12.5 0.7 2.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4407 PF14362.6 GAX10715.1 - 0.052 12.9 4.4 0.099 12.0 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 GAX10715.1 - 0.058 13.8 0.3 0.058 13.8 0.3 1.5 2 0 0 2 2 2 0 YlqD protein Hpt PF01627.23 GAX10715.1 - 0.29 11.4 6.1 0.33 11.2 4.5 2.0 1 1 0 1 1 1 0 Hpt domain Phage_Mu_F PF04233.14 GAX10715.1 - 0.3 11.8 0.9 4.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Phage Mu protein F like protein DUF1484 PF07363.11 GAX10715.1 - 7.7 7.6 6.6 6.2 7.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Prefoldin PF02996.17 GAX10716.1 - 0.01 15.8 3.8 0.01 15.8 3.8 1.9 2 0 0 2 2 2 0 Prefoldin subunit UPF0449 PF15136.6 GAX10716.1 - 0.31 11.5 7.2 0.87 10.1 7.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Spt5_N PF11942.8 GAX10716.1 - 0.56 11.2 10.9 0.34 11.9 5.7 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FliD_N PF02465.18 GAX10716.1 - 1 10.1 4.2 2 9.1 2.3 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Atg14 PF10186.9 GAX10716.1 - 2.3 7.2 8.4 3.3 6.7 8.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 GAX10716.1 - 2.8 8.2 9.5 0.77 10.0 4.5 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 GAX10716.1 - 8.1 7.1 7.4 32 5.3 7.4 2.1 1 1 0 1 1 1 0 Initiation control protein YabA RRM_1 PF00076.22 GAX10717.1 - 2.3e-61 203.5 0.1 2.8e-21 75.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX10717.1 - 7.4e-13 48.4 0.0 3e-05 24.0 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 GAX10717.1 - 9.5e-07 28.4 0.0 0.00018 21.1 0.0 2.7 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 GAX10717.1 - 1.5e-05 24.9 0.0 0.25 11.4 0.0 3.4 3 0 0 3 3 3 2 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 GAX10717.1 - 0.0011 18.9 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 GAX10717.1 - 0.0024 17.9 0.8 0.63 10.2 0.1 3.7 4 1 0 4 4 4 1 Limkain b1 RRM_3 PF08777.11 GAX10717.1 - 0.0072 16.4 0.0 1.3 9.1 0.0 3.2 3 1 0 3 3 3 1 RNA binding motif ParA PF10609.9 GAX10718.1 - 7.2e-79 264.7 0.0 1.3e-71 240.9 0.4 2.0 1 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAX10718.1 - 4.4e-12 46.2 0.0 1.3e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX10718.1 - 4.2e-08 33.3 0.0 7.8e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAX10718.1 - 2.6e-06 26.8 2.3 9.2e-05 21.8 0.4 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 GAX10718.1 - 6.7e-06 25.6 0.4 4.6e-05 22.8 0.2 1.9 2 0 0 2 2 2 1 ATPase MipZ MeaB PF03308.16 GAX10718.1 - 2.1e-05 23.7 0.1 3.2e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 GAX10718.1 - 0.00063 19.1 0.1 0.0038 16.5 0.1 2.0 2 0 0 2 2 2 1 VirC1 protein AAA_25 PF13481.6 GAX10718.1 - 0.00083 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAX10718.1 - 0.0013 17.9 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 GAX10718.1 - 0.0014 18.6 0.1 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase APS_kinase PF01583.20 GAX10718.1 - 0.0014 18.6 0.2 0.0023 17.8 0.2 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_26 PF13500.6 GAX10718.1 - 0.0014 18.5 1.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain CLP1_P PF16575.5 GAX10718.1 - 0.0017 18.2 0.1 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 GAX10718.1 - 0.002 18.5 0.1 0.0039 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 GAX10718.1 - 0.0036 16.9 0.1 0.03 14.0 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 GAX10718.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 GAX10718.1 - 0.016 15.1 0.2 0.038 13.9 0.2 1.6 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 GAX10718.1 - 0.03 14.3 0.3 0.075 12.9 0.3 1.7 2 0 0 2 2 1 0 NACHT domain AAA_30 PF13604.6 GAX10718.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAX10718.1 - 0.049 14.0 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 GAX10718.1 - 0.059 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.10 GAX10718.1 - 0.062 12.7 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CBP_BcsQ PF06564.12 GAX10718.1 - 0.091 12.2 0.3 0.21 11.1 0.2 1.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MobB PF03205.14 GAX10718.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Hpr_kinase_C PF07475.12 GAX10718.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 GAX10718.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAX10718.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 GAX10718.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DAP3 PF10236.9 GAX10718.1 - 0.2 10.8 0.1 0.34 10.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Tudor_3 PF18115.1 GAX10719.1 - 1.4e-11 44.1 0.0 4.4e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 GAX10719.1 - 1.4e-07 31.9 0.6 0.026 15.0 0.2 3.4 3 0 0 3 3 3 2 Agenet domain TUDOR_5 PF18359.1 GAX10719.1 - 0.00027 20.6 0.1 1.2 8.9 0.0 2.7 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 GAX10719.1 - 0.00082 19.4 0.0 0.075 13.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 GAX10719.1 - 0.0031 17.2 0.0 0.31 10.8 0.0 2.7 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain DUF1325 PF07039.11 GAX10719.1 - 0.005 16.9 0.0 0.56 10.3 0.0 2.4 2 0 0 2 2 2 1 SGF29 tudor-like domain LBR_tudor PF09465.10 GAX10719.1 - 0.036 13.9 0.1 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain TRAPPC9-Trs120 PF08626.11 GAX10720.1 - 1.5e-13 49.1 0.0 1.5e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Y_phosphatase3 PF13350.6 GAX10721.1 - 2.8e-42 145.3 0.1 4.3e-29 102.1 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAX10721.1 - 0.0003 20.4 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAX10721.1 - 0.02 14.5 0.1 0.042 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Ribosomal_L7Ae PF01248.26 GAX10721.1 - 0.088 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf_C2H2_6 PF18450.1 GAX10722.1 - 4.8 7.0 5.8 5.9 6.7 1.4 2.9 2 0 0 2 2 2 0 Zinc Finger domain Trigger_N PF05697.13 GAX10723.1 - 0.0006 20.2 0.1 0.001 19.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) Adap_comp_sub PF00928.21 GAX10724.1 - 8e-62 209.0 0.0 1.1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family PCI PF01399.27 GAX10725.1 - 4.5e-15 56.0 0.1 1.2e-14 54.7 0.1 1.7 1 0 0 1 1 1 1 PCI domain DDT PF02791.17 GAX10727.1 - 3.1e-13 49.8 0.2 3.1e-13 49.8 0.2 2.1 2 0 0 2 2 2 1 DDT domain WSD PF15613.6 GAX10727.1 - 4e-09 36.8 0.0 4e-09 36.8 0.0 3.1 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 GAX10727.1 - 0.063 12.8 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Aldedh PF00171.22 GAX10728.1 - 1.1e-78 264.8 0.0 1.4e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Bestrophin PF01062.21 GAX10729.1 - 1.2e-26 93.8 4.3 1.6e-26 93.4 4.3 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FSH1 PF03959.13 GAX10730.1 - 6.8e-35 120.7 0.0 2e-34 119.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) RWD PF05773.22 GAX10730.1 - 2.7e-16 59.9 0.2 5e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 RWD domain MMR_HSR1 PF01926.23 GAX10730.1 - 1.3e-11 44.6 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_C PF08438.10 GAX10730.1 - 9.1e-07 29.4 0.1 0.047 14.3 0.0 2.9 3 0 0 3 3 3 2 GTPase of unknown function C-terminal Hydrolase_4 PF12146.8 GAX10730.1 - 2.9e-05 23.5 0.4 0.072 12.4 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAX10730.1 - 0.0011 18.9 0.0 0.0036 17.2 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FeoB_N PF02421.18 GAX10730.1 - 0.0021 17.6 0.0 0.061 12.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 GAX10730.1 - 0.095 12.5 0.1 8.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 GAX10730.1 - 0.1 11.5 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 GAX10730.1 - 0.11 12.4 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Fer4_13 PF13370.6 GAX10731.1 - 1e-14 54.8 2.1 1.8e-14 54.0 2.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Lactamase_B PF00753.27 GAX10731.1 - 0.0053 16.8 4.6 0.027 14.5 3.7 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Fer4_15 PF13459.6 GAX10731.1 - 0.0074 17.0 3.6 0.035 14.8 3.6 2.1 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_7 PF12838.7 GAX10731.1 - 0.06 13.9 0.3 1.7 9.3 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAX10731.1 - 0.083 13.0 1.0 0.27 11.4 1.0 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAX10731.1 - 0.51 11.3 2.6 6 7.9 0.1 2.3 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4 PF00037.27 GAX10731.1 - 0.62 10.0 3.5 3.7 7.5 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain MFS_1 PF07690.16 GAX10734.1 - 2e-13 50.0 40.7 2e-13 50.0 40.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX10734.1 - 0.0042 16.0 34.6 0.011 14.6 6.1 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter EamA PF00892.20 GAX10735.1 - 1.4e-19 70.6 20.7 1.6e-10 41.3 10.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAX10735.1 - 0.0018 17.7 0.7 0.0031 16.9 0.3 1.6 1 1 1 2 2 2 1 Triose-phosphate Transporter family VMA21 PF09446.10 GAX10736.1 - 6.2e-14 51.9 0.1 7.9e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 VMA21-like domain Urate_ox_N PF06181.11 GAX10736.1 - 0.0031 16.9 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 Urate oxidase N-terminal Pro_isomerase PF00160.21 GAX10737.1 - 2.7e-13 50.5 0.0 4.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HemX PF04375.14 GAX10737.1 - 0.0064 15.8 1.0 0.0091 15.3 1.0 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase YvfG PF09628.10 GAX10737.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 YvfG protein Fmp27_WPPW PF10359.9 GAX10737.1 - 0.2 10.5 1.0 0.28 10.0 1.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-F_leu_zip PF10473.9 GAX10737.1 - 1.9 8.5 5.9 7.8 6.5 5.9 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nop PF01798.18 GAX10738.1 - 2.1e-82 276.0 0.2 2.1e-82 276.0 0.2 1.9 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAX10738.1 - 1.1e-18 67.3 0.4 1.1e-18 67.3 0.4 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain SAPS PF04499.15 GAX10738.1 - 3.8 6.2 11.4 5.8 5.6 11.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SASA PF03629.18 GAX10739.1 - 8.5e-16 58.3 0.0 1.1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase NCE101 PF11654.8 GAX10739.1 - 0.093 12.5 0.1 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 Non-classical export protein 1 Acetyltransf_1 PF00583.25 GAX10740.1 - 1.3e-18 67.4 0.1 1.6e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX10740.1 - 1e-11 44.9 0.2 1.3e-11 44.5 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX10740.1 - 3.7e-11 43.3 0.2 5.1e-11 42.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX10740.1 - 3.4e-06 27.1 0.1 5.5e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX10740.1 - 0.00016 21.6 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAX10740.1 - 0.00078 19.5 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 GAX10740.1 - 0.0075 16.0 0.0 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 GAX10740.1 - 0.13 11.7 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Aminotran_1_2 PF00155.21 GAX10741.1 - 1.1e-46 159.7 0.0 1.4e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_trans_4_4 PF13579.6 GAX10741.1 - 0.019 15.4 0.0 6.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF1995 PF09353.10 GAX10742.1 - 8.6e-38 130.4 0.0 1e-37 130.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Ribosomal_L22 PF00237.19 GAX10745.1 - 3.6e-22 78.5 0.0 5.9e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GPP34 PF05719.11 GAX10745.1 - 0.0055 16.8 0.1 0.0055 16.8 0.1 1.6 2 0 0 2 2 2 1 Golgi phosphoprotein 3 (GPP34) PseudoU_synth_1 PF01416.20 GAX10746.1 - 1.7e-15 57.4 0.0 4e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase RelA_SpoT PF04607.17 GAX10747.1 - 2.8e-24 85.6 0.0 5.8e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 GAX10747.1 - 6.7e-13 48.7 1.0 4.7e-12 45.9 0.2 2.7 2 1 0 2 2 2 1 HD domain Methyltransf_11 PF08241.12 GAX10748.1 - 0.0005 20.7 0.0 0.0094 16.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX10748.1 - 0.0048 16.7 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10748.1 - 0.0062 17.2 0.0 0.032 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PBP1_TM PF14812.6 GAX10748.1 - 0.2 12.1 0.0 0.2 12.1 0.0 3.4 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pex2_Pex12 PF04757.14 GAX10748.1 - 0.21 11.1 0.0 0.21 11.1 0.0 2.5 3 0 0 3 3 3 0 Pex2 / Pex12 amino terminal region adh_short PF00106.25 GAX10749.1 - 2.4e-33 115.2 1.2 3.1e-33 114.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX10749.1 - 1.8e-23 83.3 0.4 2.4e-23 82.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX10749.1 - 0.035 14.0 1.4 0.064 13.2 1.4 1.5 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 GAX10749.1 - 0.069 12.6 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box PF00646.33 GAX10750.1 - 0.8 9.7 4.8 10 6.1 0.3 2.8 2 0 0 2 2 2 0 F-box domain Bestrophin PF01062.21 GAX10752.1 - 2.2e-29 102.8 0.1 2.7e-29 102.5 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF305 PF03713.13 GAX10753.1 - 3.2e-11 43.6 10.2 2.1e-07 31.2 2.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF305) Amino_oxidase PF01593.24 GAX10754.1 - 3.9e-20 72.6 0.0 1.3e-19 70.9 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX10754.1 - 1.4e-13 50.9 0.0 3.2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX10754.1 - 7.8e-10 38.4 0.3 4.1e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 GAX10754.1 - 8.3e-06 25.2 0.4 2.2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAX10754.1 - 2e-05 24.4 1.9 0.00029 20.5 1.8 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX10754.1 - 0.0004 19.2 0.2 0.059 12.1 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 GAX10754.1 - 0.00041 19.7 0.0 0.00071 18.9 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAX10754.1 - 0.0012 17.9 0.6 0.0049 16.0 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAX10754.1 - 0.0013 18.0 0.2 0.0047 16.2 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 GAX10754.1 - 0.0015 17.1 0.0 0.22 10.0 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor GIDA PF01134.22 GAX10754.1 - 0.0054 15.9 0.7 1.7 7.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAX10754.1 - 0.0066 15.7 0.2 0.034 13.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX10754.1 - 0.014 15.9 0.4 0.12 12.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAX10754.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 MCRA family CDC50 PF03381.15 GAX10756.1 - 3.3e-66 223.7 0.1 3.3e-66 223.7 0.1 1.6 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 GAX10756.1 - 0.21 11.6 1.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) RICTOR_N PF14664.6 GAX10756.1 - 0.24 10.4 0.3 0.35 9.8 0.3 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Orf78 PF06024.12 GAX10756.1 - 0.29 11.5 3.5 0.64 10.4 3.5 1.5 1 0 0 1 1 1 0 Orf78 (ac78) ETRAMP PF09716.10 GAX10756.1 - 1 9.4 4.6 2.3 8.4 4.6 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RuvX PF03652.15 GAX10757.1 - 0.036 14.5 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Fumerase_C PF05683.12 GAX10758.1 - 1.6e-85 285.6 0.0 3.8e-85 284.4 0.0 1.6 2 0 0 2 2 2 1 Fumarase C-terminus Fumerase PF05681.14 GAX10758.1 - 7.9e-84 281.3 0.0 1.1e-83 280.8 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) HCO3_cotransp PF00955.21 GAX10759.1 - 1.6e-83 281.3 9.3 1.2e-48 166.2 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family Pex19 PF04614.12 GAX10760.1 - 0.15 11.8 3.9 5 6.8 3.6 2.0 2 0 0 2 2 2 0 Pex19 protein family Rhomboid PF01694.22 GAX10761.1 - 0.0015 18.6 1.6 0.0015 18.6 1.6 1.8 2 0 0 2 2 2 1 Rhomboid family Peptidase_U4 PF03419.13 GAX10761.1 - 0.085 12.1 2.2 0.39 10.0 1.0 2.1 1 1 0 2 2 2 0 Sporulation factor SpoIIGA DoxX PF07681.12 GAX10763.1 - 1.1e-11 45.1 4.5 1.1e-11 45.1 4.5 1.7 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 GAX10763.1 - 0.003 17.5 0.2 0.017 15.0 0.2 2.0 1 1 0 1 1 1 1 TQO small subunit DoxD DoxX_2 PF13564.6 GAX10763.1 - 0.3 11.2 8.4 0.056 13.6 4.4 2.0 2 1 0 2 2 2 0 DoxX-like family CLASP_N PF12348.8 GAX10764.1 - 2.5e-13 50.1 0.0 4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 GAX10764.1 - 0.0019 18.3 2.6 1.2 9.6 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 GAX10764.1 - 0.17 12.3 0.1 6.4 7.2 0.0 2.7 1 1 0 2 2 2 0 HEAT repeats PP2C PF00481.21 GAX10765.1 - 7.3e-56 189.7 0.0 1.5e-55 188.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 GAX10765.1 - 6e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain PP2C_2 PF13672.6 GAX10765.1 - 2e-05 24.3 0.0 7.4e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Yop-YscD_cpl PF16697.5 GAX10765.1 - 0.00038 20.7 0.0 0.0019 18.5 0.0 2.1 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Ferric_reduct PF01794.19 GAX10766.1 - 0.01 15.9 4.5 0.01 15.9 4.5 2.2 1 1 1 2 2 2 0 Ferric reductase like transmembrane component HPP PF04982.13 GAX10766.1 - 0.044 14.0 1.3 0.093 12.9 0.2 2.1 2 0 0 2 2 2 0 HPP family STI1 PF17830.1 GAX10767.1 - 6.6e-10 38.8 5.8 6.4e-08 32.4 4.2 2.9 2 1 0 2 2 2 1 STI1 domain SAP PF02037.27 GAX10767.1 - 3.2e-06 26.7 2.4 0.099 12.4 0.4 4.0 4 0 0 4 4 4 2 SAP domain Armet PF10208.9 GAX10767.1 - 0.00011 22.2 0.1 0.072 13.0 0.1 2.3 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding Snf7 PF03357.21 GAX10767.1 - 0.0013 18.3 3.0 0.003 17.2 0.1 2.2 2 0 0 2 2 2 1 Snf7 SR-25 PF10500.9 GAX10767.1 - 0.0021 17.7 10.1 0.0032 17.1 10.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein HeH PF12949.7 GAX10767.1 - 0.043 13.5 0.0 9 6.1 0.0 2.4 2 0 0 2 2 2 0 HeH/LEM domain Rho_N PF07498.12 GAX10767.1 - 0.047 13.6 2.9 0.47 10.4 0.1 2.7 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain BCNT PF07572.12 GAX10767.1 - 0.17 12.0 2.3 2.5 8.2 1.0 2.6 2 1 0 2 2 2 0 Bucentaur or craniofacial development WDCP PF15390.6 GAX10767.1 - 0.24 9.7 3.8 0.32 9.3 3.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family GA-like PF17573.2 GAX10767.1 - 0.68 9.9 5.1 25 4.9 0.1 3.1 2 2 0 2 2 2 0 GA-like domain GerD PF17898.1 GAX10767.1 - 2.3 8.2 10.0 0.35 10.8 0.5 2.9 3 1 0 3 3 3 0 Spore germination GerD central core domain Abhydrolase_6 PF12697.7 GAX10768.1 - 7.6e-13 49.6 4.3 1.1e-12 49.1 4.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX10768.1 - 9.7e-10 38.1 0.0 1.9e-08 33.9 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX10768.1 - 9.3e-07 28.7 0.0 0.052 13.2 0.0 2.7 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 GAX10768.1 - 0.019 14.6 0.0 0.15 11.7 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 GAX10768.1 - 0.089 12.9 0.0 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein Thioesterase PF00975.20 GAX10768.1 - 0.13 12.3 0.0 0.67 10.0 0.0 1.9 1 1 0 1 1 1 0 Thioesterase domain Cyclin_N PF00134.23 GAX10769.1 - 4.2e-12 45.9 0.0 8.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX10769.1 - 2.5e-05 24.3 0.0 0.00026 21.1 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF776 PF05604.11 GAX10769.1 - 0.13 12.6 3.5 0.22 11.9 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF776) SDA1 PF05285.12 GAX10770.1 - 0.8 9.1 9.1 0.81 9.0 9.1 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 GAX10770.1 - 1.4 7.4 6.6 1.4 7.4 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Kdo PF06293.14 GAX10771.1 - 5.2e-11 42.3 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAX10771.1 - 1.9e-09 37.3 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 GAX10771.1 - 4.4e-09 36.2 0.1 8.9e-09 35.2 0.0 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 GAX10771.1 - 1.2e-07 32.0 0.5 6.8e-05 22.9 0.5 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GAX10771.1 - 1.8e-06 27.4 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2939 PF11159.8 GAX10771.1 - 0.0016 18.8 0.2 0.0051 17.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2939) Pkinase_fungal PF17667.1 GAX10771.1 - 0.079 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 GAX10771.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Ribosomal_TL5_C PF14693.6 GAX10772.1 - 0.037 14.4 0.1 0.074 13.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain FA_desaturase PF00487.24 GAX10773.1 - 7.3e-29 101.4 6.5 1e-28 100.9 6.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 GAX10773.1 - 2e-21 75.2 1.1 3.1e-21 74.6 0.2 1.8 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) DnaJ PF00226.31 GAX10774.1 - 1.9e-22 79.2 2.0 3.6e-22 78.2 2.0 1.5 1 0 0 1 1 1 1 DnaJ domain MPM1 PF17234.2 GAX10774.1 - 0.002 18.4 0.4 0.002 18.4 0.4 2.3 2 0 0 2 2 2 1 Mitochondrial peculiar membrane protein 1 Rod_C PF10493.9 GAX10774.1 - 0.41 9.0 1.0 0.88 7.9 0.4 1.7 2 0 0 2 2 2 0 Rough deal protein C-terminal region BTB_2 PF02214.22 GAX10775.1 - 3.7e-16 59.3 0.0 8.4e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX10775.1 - 0.0077 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HOASN PF14515.6 GAX10775.1 - 0.047 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices FAM76 PF16046.5 GAX10775.1 - 0.061 12.7 1.0 0.063 12.6 1.0 1.3 1 1 0 1 1 1 0 FAM76 protein TubC_N PF18563.1 GAX10775.1 - 0.12 12.4 0.8 44 4.2 0.0 3.2 3 0 0 3 3 3 0 TubC N-terminal docking domain F-box PF00646.33 GAX10777.1 - 0.00051 19.8 0.6 0.00051 19.8 0.6 2.2 2 0 0 2 2 2 1 F-box domain Ank_5 PF13857.6 GAX10777.1 - 0.0017 18.6 0.3 0.016 15.5 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Tsc35 PF15079.6 GAX10777.1 - 0.021 14.4 0.6 0.021 14.4 0.6 1.8 2 0 0 2 2 2 0 Testis-specific protein 35 Ank_4 PF13637.6 GAX10777.1 - 0.039 14.6 0.0 0.095 13.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RRF PF01765.19 GAX10777.1 - 0.041 13.9 4.2 0.11 12.5 4.0 1.8 2 0 0 2 2 2 0 Ribosome recycling factor FdhD-NarQ PF02634.15 GAX10777.1 - 0.064 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 FdhD/NarQ family Cor1 PF04803.12 GAX10777.1 - 6.5 7.0 12.5 4.1 7.6 0.3 2.8 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region F-box PF00646.33 GAX10778.1 - 0.00018 21.3 0.6 0.00051 19.9 0.6 1.8 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.7 GAX10778.1 - 0.00052 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX10778.1 - 0.012 16.1 0.9 1.1 9.8 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 GAX10778.1 - 0.012 15.9 0.1 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX10778.1 - 0.014 16.0 0.0 0.034 14.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PI3_PI4_kinase PF00454.27 GAX10779.1 - 2.9e-33 115.8 0.3 8e-31 107.7 0.3 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAX10779.1 - 0.0025 17.2 0.0 0.0082 15.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2975 PF11188.8 GAX10779.1 - 0.38 10.6 3.9 2.5 8.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) V-SNARE_C PF12352.8 GAX10780.1 - 3.7e-09 36.7 7.2 3.7e-09 36.7 7.2 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAX10780.1 - 3.5e-05 23.6 2.1 7e-05 22.7 0.4 2.0 2 0 0 2 2 2 1 Sec20 PLU-1 PF08429.11 GAX10780.1 - 0.0035 16.6 4.5 0.31 10.2 1.3 2.1 1 1 0 2 2 2 2 PLU-1-like protein Prominin PF05478.11 GAX10780.1 - 0.0083 14.1 2.0 0.01 13.8 2.0 1.2 1 0 0 1 1 1 1 Prominin TMP_2 PF06791.13 GAX10780.1 - 0.077 12.7 3.4 0.2 11.3 0.6 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein Synaptobrevin PF00957.21 GAX10780.1 - 0.11 12.3 0.6 0.24 11.2 0.6 1.6 1 0 0 1 1 1 0 Synaptobrevin TMPIT PF07851.13 GAX10780.1 - 0.23 10.7 2.9 0.23 10.7 0.4 1.9 1 1 1 2 2 2 0 TMPIT-like protein O-FucT PF10250.9 GAX10781.1 - 5.8e-06 26.2 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase BRO1 PF03097.18 GAX10782.1 - 3.8e-18 65.5 0.3 4.9e-18 65.1 0.3 1.1 1 0 0 1 1 1 1 BRO1-like domain Josephin PF02099.17 GAX10785.1 - 3.2e-38 131.4 0.2 7.8e-38 130.1 0.1 1.6 2 0 0 2 2 2 1 Josephin UBX PF00789.20 GAX10785.1 - 2e-11 44.0 0.0 3.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 GAX10785.1 - 0.12 12.4 1.3 0.71 9.9 1.3 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif RabGAP-TBC PF00566.18 GAX10786.1 - 0.0047 16.6 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 GAX10786.1 - 0.0079 16.7 0.0 0.052 14.1 0.0 2.4 1 1 0 1 1 1 1 Rhodanese-like domain Activator-TraM PF11657.8 GAX10786.1 - 0.5 10.2 4.0 14 5.5 0.1 2.6 2 0 0 2 2 2 0 Transcriptional activator TraM GlcNAc PF11397.8 GAX10787.1 - 3.1e-71 240.7 0.0 8.9e-70 235.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Pkinase PF00069.25 GAX10790.1 - 1.3e-70 237.7 0.0 1.9e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10790.1 - 2.1e-36 125.5 0.1 3.7e-36 124.7 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX10790.1 - 0.00022 20.3 0.2 0.00042 19.4 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAX10790.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LTXXQ PF07813.12 GAX10790.1 - 0.048 14.4 0.0 0.092 13.5 0.0 1.4 1 0 0 1 1 1 0 LTXXQ motif family protein Pox_VLTF3 PF04947.14 GAX10790.1 - 0.049 13.4 1.6 0.096 12.4 1.6 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like FTA2 PF13095.6 GAX10790.1 - 0.071 12.7 0.1 0.21 11.2 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAX10790.1 - 0.17 11.7 0.2 0.6 10.0 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DEAD PF00270.29 GAX10791.1 - 1.9e-20 73.3 0.0 3.3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-GRF PF06839.12 GAX10791.1 - 4.2e-15 55.6 0.8 1.2e-14 54.2 0.8 1.8 1 0 0 1 1 1 1 GRF zinc finger RQC PF09382.10 GAX10791.1 - 3.9e-13 49.2 0.0 9.3e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 GAX10791.1 - 3.1e-09 36.7 0.0 7.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.31 GAX10791.1 - 1.8e-06 28.2 0.1 9.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX10791.1 - 0.00013 22.0 0.0 0.00044 20.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DHNA PF04038.12 GAX10791.1 - 0.12 12.8 0.0 13 6.4 0.0 2.7 2 0 0 2 2 2 0 Dihydroneopterin aldolase bHLH-MYC_N PF14215.6 GAX10792.1 - 0.00048 20.5 0.1 0.0031 17.8 0.0 2.2 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal PX PF00787.24 GAX10793.1 - 0.00088 19.2 0.0 0.018 15.0 0.0 2.4 1 1 0 1 1 1 1 PX domain PTS_IIA PF02255.16 GAX10793.1 - 0.91 9.6 4.9 2.7 8.1 4.9 1.8 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit PCI PF01399.27 GAX10794.1 - 6.1e-15 55.6 0.1 1.4e-14 54.5 0.1 1.7 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 GAX10794.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family ADK PF00406.22 GAX10795.1 - 6.1e-45 153.0 0.0 8e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX10795.1 - 5.7e-21 75.4 0.0 1.2e-20 74.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 GAX10795.1 - 1.6e-15 56.8 0.0 2.7e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAX10795.1 - 2e-06 28.3 0.0 4.3e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX10795.1 - 0.0034 17.6 0.0 0.0079 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAX10795.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 GAX10795.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAX10795.1 - 0.037 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 GAX10795.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_10 PF12846.7 GAX10795.1 - 0.13 11.2 0.0 0.55 9.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.21 GAX10795.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Hydrolase_4 PF12146.8 GAX10796.1 - 5.3e-11 42.3 0.1 5.8e-05 22.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX10796.1 - 4.9e-08 32.9 0.2 0.005 16.5 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX10796.1 - 5.9e-07 29.2 0.0 0.00012 21.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAX10796.1 - 0.00012 22.0 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 GAX10796.1 - 0.0068 16.1 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 GAX10796.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 GAX10796.1 - 0.029 13.9 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 GAX10796.1 - 0.035 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_5 PF12695.7 GAX10796.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase family LIP PF03583.14 GAX10796.1 - 0.06 12.7 0.1 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase DUF1749 PF08538.10 GAX10796.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) PRA1 PF03208.19 GAX10798.1 - 3.4e-15 55.9 9.1 8.5e-15 54.6 9.1 1.6 1 1 0 1 1 1 1 PRA1 family protein Promethin PF16015.5 GAX10798.1 - 0.59 10.1 11.3 1.1 9.2 0.8 2.2 2 0 0 2 2 2 0 Promethin Phage_holin_3_6 PF07332.11 GAX10798.1 - 1.5 8.9 10.4 15 5.7 10.4 2.1 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM239 PF15841.5 GAX10798.1 - 8.8 6.2 7.4 7.2 6.5 5.7 1.7 1 1 0 1 1 1 0 Transmembrane protein 239 family Hist_deacetyl PF00850.19 GAX10800.1 - 2.1e-27 96.4 0.0 2.7e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DnaJ PF00226.31 GAX10802.1 - 1.9e-27 95.2 3.8 3e-27 94.5 3.8 1.3 1 0 0 1 1 1 1 DnaJ domain Cadherin-like PF12733.7 GAX10802.1 - 0.13 12.8 0.0 0.65 10.6 0.0 2.1 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain Las1 PF04031.13 GAX10803.1 - 4.1e-36 124.4 2.9 9.8e-36 123.2 2.9 1.7 1 0 0 1 1 1 1 Las1-like DUF2407 PF10302.9 GAX10803.1 - 0.18 12.4 1.5 0.33 11.5 0.1 2.1 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain SET PF00856.28 GAX10804.1 - 1.9e-17 64.2 0.3 1.9e-17 64.2 0.3 2.2 2 2 0 2 2 2 1 SET domain MMR_HSR1 PF01926.23 GAX10805.1 - 9.1e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX10805.1 - 3.8e-06 26.5 0.1 1.2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX10805.1 - 0.00062 19.7 0.2 0.13 12.1 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 GAX10805.1 - 0.043 14.4 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAX10805.1 - 0.27 11.3 2.1 0.5 10.4 0.2 2.2 2 1 1 3 3 3 0 Dynamin family TIM PF00121.18 GAX10806.1 - 3.3e-67 226.4 0.0 3.9e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase GST_C_3 PF14497.6 GAX10807.1 - 7.9e-16 58.1 1.1 1.3e-15 57.4 0.8 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX10807.1 - 0.0026 17.7 0.0 0.0063 16.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX10807.1 - 0.017 15.3 0.4 0.046 14.0 0.2 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Nop PF01798.18 GAX10808.1 - 2.4e-56 190.8 0.0 4.2e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 GAX10808.1 - 1.6e-28 100.0 7.3 3.2e-28 99.1 7.3 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain WD40 PF00400.32 GAX10810.1 - 5.9e-20 71.2 26.8 2.4e-05 25.0 0.7 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 GAX10810.1 - 1.1e-10 41.9 0.1 2.1e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 GAX10810.1 - 0.0014 18.9 2.7 2.2 8.6 0.1 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX10810.1 - 0.081 13.4 0.3 8.7 7.0 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Baculo_LEF5 PF04838.12 GAX10811.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 Methyltransf_23 PF13489.6 GAX10811.1 - 0.027 14.3 0.0 0.043 13.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 GAX10812.1 - 9.8e-21 73.4 0.0 1.4e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 GAX10812.1 - 7.2e-09 36.2 8.1 1.6e-08 35.1 8.1 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 GAX10812.1 - 0.17 12.1 0.0 0.5 10.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Amidohydro_2 PF04909.14 GAX10813.1 - 3.3e-36 125.6 0.1 3.8e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Gamma_PGA_hydro PF05908.11 GAX10814.1 - 0.036 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase DUF501 PF04417.12 GAX10815.1 - 5.8e-29 100.7 0.5 1.5e-28 99.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF501) RSN1_7TM PF02714.15 GAX10816.1 - 3.7e-51 174.0 18.9 8.6e-51 172.9 18.9 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX10816.1 - 3.5e-28 98.3 2.8 3.5e-28 98.3 2.8 3.5 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX10816.1 - 5.1e-20 72.4 0.0 1.4e-12 48.2 0.0 2.8 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter LNS2 PF08235.13 GAX10817.1 - 2.7e-33 115.3 0.0 3.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Nup54 PF13874.6 GAX10818.1 - 5.3e-22 78.4 7.4 5.3e-22 78.4 7.4 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 GAX10818.1 - 2.4e-07 31.5 50.3 71 4.3 50.3 3.4 1 1 0 1 1 1 0 Nucleoporin FG repeat region Nup88 PF10168.9 GAX10818.1 - 0.0017 16.3 5.0 0.0025 15.7 5.0 1.1 1 0 0 1 1 1 1 Nuclear pore component Lge1 PF11488.8 GAX10818.1 - 0.081 13.1 2.5 0.23 11.7 2.5 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 B2 PF11473.8 GAX10818.1 - 0.13 12.1 0.5 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 RNA binding protein B2 DUF4201 PF13870.6 GAX10818.1 - 0.32 10.7 6.0 0.3 10.8 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) BRE1 PF08647.11 GAX10818.1 - 1.6 8.9 7.8 0.46 10.6 3.2 2.3 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase TauE PF01925.19 GAX10819.1 - 0.17 11.5 10.8 7.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Methyltransf_23 PF13489.6 GAX10820.1 - 3.2e-17 62.9 0.0 1.1e-16 61.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX10820.1 - 1.7e-15 57.4 0.1 9.5e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10820.1 - 2e-14 54.1 0.2 4.1e-14 53.1 0.1 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10820.1 - 2.6e-14 53.7 0.1 4.5e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX10820.1 - 5.3e-12 45.8 0.0 9.7e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX10820.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX10820.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 GAX10820.1 - 0.00038 19.8 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 GAX10820.1 - 0.00049 19.8 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 GAX10820.1 - 0.004 17.1 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 GAX10820.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 GAX10820.1 - 0.014 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 GAX10820.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 GAX10820.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.11 GAX10820.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ribosomal_S9 PF00380.19 GAX10821.1 - 4.4e-43 146.6 0.0 8.2e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 IML1 PF12257.8 GAX10822.1 - 2.5e-88 295.9 0.0 4e-88 295.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DUF4279 PF14106.6 GAX10822.1 - 0.045 14.0 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) AalphaY_MDB PF04611.12 GAX10823.1 - 0.0056 16.7 0.1 0.024 14.6 0.1 2.1 1 0 0 1 1 1 1 Mating type protein A alpha Y mating type dependent binding region LRR_8 PF13855.6 GAX10824.1 - 6.2e-12 45.1 7.0 0.00028 20.6 0.1 3.9 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 GAX10824.1 - 6e-10 39.2 2.8 0.0038 17.6 0.2 4.6 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX10824.1 - 1.6e-05 24.8 0.6 0.97 10.2 0.2 5.5 4 2 0 4 4 4 1 Leucine Rich Repeat Glyco_hydr_30_2 PF14587.6 GAX10824.1 - 0.091 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 DNA_pol_A_exo1 PF01612.20 GAX10825.1 - 8.6e-33 113.5 1.7 1.3e-32 112.9 1.7 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 GAX10825.1 - 2.8e-10 40.0 0.1 8.7e-10 38.5 0.1 1.9 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 GAX10825.1 - 1.4e-09 38.5 2.0 9.6e-09 35.8 0.2 2.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain DUF1003 PF06210.11 GAX10825.1 - 0.23 11.6 0.8 0.52 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Astro_capsid_p PF12226.8 GAX10825.1 - 2.6 7.1 10.7 0.11 11.6 3.8 2.1 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Lactamase_B_2 PF12706.7 GAX10826.1 - 2.6e-19 69.5 1.1 1.1e-17 64.3 0.2 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX10826.1 - 1.2e-12 48.2 0.2 2.5e-05 24.4 0.2 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 GAX10826.1 - 6.9e-09 35.3 0.0 3.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_6 PF16661.5 GAX10826.1 - 3.9e-05 23.2 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain 7TMR-HDED PF07697.11 GAX10828.1 - 0.00078 19.6 0.1 0.0016 18.6 0.1 1.4 1 1 0 1 1 1 1 7TM-HD extracellular LETM1 PF07766.13 GAX10828.1 - 0.0016 17.9 3.7 0.015 14.6 0.1 2.2 1 1 1 2 2 2 1 LETM1-like protein THOC7 PF05615.13 GAX10828.1 - 0.0023 18.2 2.6 0.0045 17.3 2.6 1.5 1 0 0 1 1 1 1 Tho complex subunit 7 DUF2312 PF10073.9 GAX10828.1 - 0.0029 17.2 3.0 0.0077 15.9 3.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) Prominin PF05478.11 GAX10828.1 - 0.0073 14.3 0.5 0.0091 14.0 0.5 1.3 1 0 0 1 1 1 1 Prominin MscS_porin PF12795.7 GAX10828.1 - 0.0073 15.9 7.6 0.013 15.1 7.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain GAS PF13851.6 GAX10828.1 - 0.017 14.5 4.7 0.025 13.9 4.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Het-C PF07217.11 GAX10828.1 - 0.017 13.7 0.3 0.025 13.1 0.3 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF148 PF02520.17 GAX10828.1 - 0.025 14.7 2.3 0.032 14.4 1.2 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF148 AAA_13 PF13166.6 GAX10828.1 - 0.032 12.9 1.9 0.043 12.5 1.9 1.2 1 0 0 1 1 1 0 AAA domain Herpes_UL6 PF01763.16 GAX10828.1 - 0.035 12.6 1.6 0.051 12.1 1.5 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF4337 PF14235.6 GAX10828.1 - 0.077 13.1 2.4 0.14 12.3 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_23 PF13476.6 GAX10828.1 - 0.081 13.4 2.4 0.12 12.9 2.4 1.3 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 GAX10828.1 - 0.12 12.4 2.3 0.59 10.1 2.8 2.0 2 1 0 2 2 2 0 Laminin Domain II DUF2203 PF09969.9 GAX10828.1 - 0.14 12.9 1.4 0.29 11.9 1.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 GAX10828.1 - 0.2 10.2 1.6 0.27 9.8 1.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 GAX10828.1 - 0.21 9.5 1.8 0.27 9.1 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 GAX10828.1 - 0.25 11.6 3.2 0.47 10.7 3.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 GAX10828.1 - 0.41 11.1 5.2 1.6 9.2 2.4 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) KELK PF15796.5 GAX10828.1 - 0.47 10.9 7.8 1 9.9 7.6 1.7 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DivIC PF04977.15 GAX10828.1 - 0.55 10.0 7.3 1.5 8.6 7.1 2.0 1 1 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 GAX10828.1 - 0.78 10.3 14.0 1.3 9.5 14.0 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 GAX10828.1 - 1.3 9.3 6.3 2.2 8.6 4.8 2.0 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF1192 PF06698.11 GAX10828.1 - 1.9 8.6 10.2 2.8 8.1 4.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Peptidase_S49 PF01343.18 GAX10829.1 - 4.8e-56 189.0 0.0 6.7e-41 139.8 0.0 3.3 2 1 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 GAX10829.1 - 2.9e-05 24.0 0.1 0.041 13.8 0.0 3.2 3 0 0 3 3 3 2 Clp protease SDH_sah PF01972.16 GAX10829.1 - 0.0062 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Thioredoxin PF00085.20 GAX10832.1 - 5e-26 90.7 0.0 2.2e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 GAX10832.1 - 1.8e-06 28.0 0.0 0.00056 19.9 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX10832.1 - 2.2e-05 24.7 0.1 0.1 12.9 0.0 4.1 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX10832.1 - 0.0093 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 GAX10832.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.1 3 0 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 GAX10832.1 - 0.024 15.1 0.2 0.19 12.2 0.1 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX10832.1 - 0.048 13.9 0.1 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like TPR_2 PF07719.17 GAX10833.1 - 5.2e-43 141.7 31.1 7.6e-07 28.8 0.0 11.8 11 1 1 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10833.1 - 2.9e-41 137.7 24.9 3.6e-08 32.9 0.4 11.2 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10833.1 - 1.9e-28 96.3 12.6 0.00019 21.4 0.0 10.6 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAX10833.1 - 2.9e-27 95.0 21.1 3.6e-07 30.7 0.0 7.9 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10833.1 - 1.3e-26 91.9 0.4 0.00014 21.5 0.1 9.2 5 2 4 9 9 9 7 TPR repeat TPR_19 PF14559.6 GAX10833.1 - 4.2e-25 88.0 25.5 3.4e-06 27.5 0.5 8.6 5 4 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAX10833.1 - 3.4e-24 83.5 21.9 0.0032 18.2 0.0 10.7 4 2 6 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX10833.1 - 1.2e-21 76.7 31.9 7.4e-15 54.9 6.2 6.2 4 2 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAX10833.1 - 1.3e-20 73.4 25.6 0.00098 19.4 0.5 9.1 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 GAX10833.1 - 9.7e-20 69.5 17.2 0.032 14.6 0.2 10.9 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX10833.1 - 9.5e-18 62.9 7.2 0.00066 19.5 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10833.1 - 8.4e-13 48.3 18.7 0.051 13.7 0.1 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX10833.1 - 2.6e-07 30.8 28.3 8.4 7.3 0.0 11.3 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAX10833.1 - 1.1e-06 28.1 5.2 0.068 12.4 0.0 4.8 3 1 3 6 6 6 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GAX10833.1 - 8.6e-05 22.5 3.2 0.0033 17.4 0.6 3.4 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_10 PF13374.6 GAX10833.1 - 0.00044 20.0 20.2 0.2 11.6 0.1 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX10833.1 - 0.0023 18.0 18.1 4.2 7.5 0.5 7.3 8 1 1 9 9 9 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 GAX10833.1 - 0.0037 17.6 1.3 1.6 9.1 0.5 4.6 3 1 3 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAX10833.1 - 0.0081 15.9 2.3 0.19 11.4 0.2 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain Med27 PF11571.8 GAX10833.1 - 0.014 15.8 0.3 0.6 10.5 0.1 2.9 2 0 0 2 2 2 0 Mediator complex subunit 27 ChAPs PF09295.10 GAX10833.1 - 0.019 14.0 0.1 0.46 9.4 0.0 2.7 3 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 GAX10833.1 - 0.024 15.3 9.5 24 5.9 0.0 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat NARP1 PF12569.8 GAX10833.1 - 0.032 13.2 1.6 4.6 6.0 0.1 3.0 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.10 GAX10833.1 - 0.033 13.8 0.2 0.46 10.1 0.0 2.8 3 1 1 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4919 PF16266.5 GAX10833.1 - 0.046 13.7 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) BTAD PF03704.17 GAX10833.1 - 0.42 11.0 6.8 13 6.2 0.5 4.0 4 0 0 4 4 3 0 Bacterial transcriptional activator domain PPR PF01535.20 GAX10833.1 - 1 9.8 3.4 49 4.5 0.1 4.1 4 0 0 4 4 3 0 PPR repeat TPR_3 PF07720.12 GAX10833.1 - 8.9 6.4 18.4 0.1 12.6 0.8 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 GAX10834.1 - 9.3e-21 74.3 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Metallophos PF00149.28 GAX10835.1 - 1e-31 111.1 0.1 1.6e-31 110.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 GAX10835.1 - 1.8e-21 76.3 0.0 3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.17 GAX10835.1 - 2.2e-11 43.0 9.9 0.00067 19.6 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10835.1 - 2.4e-11 43.0 12.9 0.00034 20.3 0.1 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAX10835.1 - 4.1e-07 30.1 4.1 0.00012 22.1 0.6 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX10835.1 - 2.2e-06 27.2 5.8 0.0026 17.4 0.2 3.3 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 GAX10835.1 - 2e-05 25.2 3.6 0.0015 19.1 1.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX10835.1 - 2.5e-05 24.1 9.1 0.032 14.4 0.1 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX10835.1 - 0.00041 20.8 1.9 0.38 11.3 0.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX10835.1 - 0.00052 20.6 0.4 3 8.9 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX10835.1 - 0.0025 18.1 8.3 0.48 10.9 0.2 3.8 5 0 0 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX10835.1 - 0.0089 16.1 0.9 2.5 8.3 0.1 2.6 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 GAX10835.1 - 0.012 15.9 3.4 0.64 10.3 1.9 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribonuc_red_sm PF00268.21 GAX10836.1 - 1.7e-109 365.6 0.0 2.1e-109 365.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HAD PF12710.7 GAX10836.1 - 0.086 13.2 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA-synt_1c PF00749.21 GAX10838.1 - 9.2e-103 343.4 0.2 1.4e-102 342.8 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAX10838.1 - 7e-34 117.2 0.1 2e-33 115.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain WHEP-TRS PF00458.20 GAX10838.1 - 1e-08 35.2 0.7 1e-08 35.2 0.7 2.2 2 0 0 2 2 2 1 WHEP-TRS domain GST_C_3 PF14497.6 GAX10838.1 - 3.2e-07 30.5 0.1 0.00048 20.3 0.0 3.0 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX10838.1 - 1.4e-06 28.4 0.5 8.4e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 GAX10838.1 - 0.018 14.4 0.8 0.018 14.4 0.8 2.1 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 GAX10838.1 - 0.057 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spt20 PF12090.8 GAX10838.1 - 1.3 8.6 10.3 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Spt20 family FIVAR PF07554.13 GAX10838.1 - 8.4 7.2 16.8 5.8 7.7 0.4 2.9 2 0 0 2 2 2 0 FIVAR domain TetR_C_6 PF13977.6 GAX10839.1 - 0.1 12.8 0.2 0.3 11.3 0.2 1.8 1 1 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal TPT PF03151.16 GAX10840.1 - 7.1e-29 101.1 17.0 9.4e-29 100.7 17.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family Dimerisation2 PF16864.5 GAX10841.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain NOT2_3_5 PF04153.18 GAX10842.1 - 2.5e-23 82.6 3.2 5e-23 81.6 3.2 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Transglycosylas PF06737.14 GAX10842.1 - 0.063 13.9 1.0 0.19 12.4 1.0 1.7 1 0 0 1 1 1 0 Transglycosylase-like domain SHMT PF00464.19 GAX10843.1 - 1.2e-196 653.0 0.0 1.4e-196 652.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 GAX10843.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Synaptobrevin PF00957.21 GAX10844.1 - 1.6e-30 104.8 0.2 2.3e-30 104.2 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAX10844.1 - 5.6e-21 74.4 0.1 8.7e-21 73.8 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.8 GAX10844.1 - 0.055 14.5 0.1 0.14 13.3 0.1 1.6 1 0 0 1 1 1 0 SpoIIAA-like Rieske_2 PF13806.6 GAX10845.1 - 4.1e-21 74.9 0.0 5.4e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 GAX10845.1 - 6.7e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Methyltransf_11 PF08241.12 GAX10846.1 - 6.8e-11 42.7 0.0 1.8e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10846.1 - 2.7e-06 28.0 0.1 6.5e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX10846.1 - 3e-05 23.5 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX10846.1 - 7.9e-05 23.3 0.3 0.00022 21.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX10846.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAX10846.1 - 0.0081 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 GAX10846.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_31 PF13847.6 GAX10846.1 - 0.021 14.6 0.0 0.067 13.0 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain DRE2_N PF16803.5 GAX10846.1 - 0.035 14.4 0.2 0.74 10.1 0.0 2.5 2 1 1 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus MTS PF05175.14 GAX10846.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain LRR_4 PF12799.7 GAX10848.1 - 2.2e-10 40.6 1.6 0.069 13.6 0.1 5.0 2 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX10848.1 - 1.7e-08 34.1 2.0 0.015 15.0 0.0 4.3 2 2 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 GAX10848.1 - 0.00038 20.6 11.2 71 4.6 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat Titin_Ig-rpts PF06582.12 GAX10848.1 - 1.2 9.2 3.5 0.57 10.2 0.4 1.9 2 0 0 2 2 2 0 Titin repeat 2OG-FeII_Oxy_3 PF13640.6 GAX10849.1 - 3.8e-13 50.1 0.1 7.4e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PTPLA PF04387.14 GAX10849.1 - 9.7e-13 48.2 3.3 8.3e-10 38.7 0.7 2.5 1 1 1 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA 2OG-FeII_Oxy_4 PF13661.6 GAX10849.1 - 2.8e-09 37.5 0.0 6.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FeS PF04060.13 GAX10849.1 - 0.019 14.6 0.3 0.039 13.6 0.3 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster RNA_pol_L_2 PF13656.6 GAX10850.1 - 6.2e-28 96.4 0.0 1.2e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAX10850.1 - 8.6e-08 31.5 0.0 1.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MbeD_MobD PF04899.12 GAX10850.1 - 0.02 15.0 0.4 0.029 14.5 0.4 1.2 1 0 0 1 1 1 0 MbeD/MobD like RINGv PF12906.7 GAX10851.1 - 1.3e-13 50.9 6.0 2.8e-13 49.7 6.0 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 GAX10851.1 - 0.25 11.7 6.1 0.46 10.8 6.1 1.5 1 0 0 1 1 1 0 Ring finger domain Drc1-Sld2 PF11719.8 GAX10851.1 - 0.26 10.8 2.6 0.39 10.2 2.6 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Ribosomal_L23 PF00276.20 GAX10852.1 - 2.8e-16 59.7 0.6 3.6e-16 59.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 TCR PF03638.15 GAX10854.1 - 9.6e-23 80.2 53.7 1.1e-11 44.9 20.5 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 GAX10854.1 - 4.6 7.4 43.5 7.4 6.8 20.0 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 2OG-FeII_Oxy_3 PF13640.6 GAX10856.1 - 2.8e-09 37.7 0.0 5.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CesT PF05932.13 GAX10856.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family GRA6 PF05084.13 GAX10857.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Granule antigen protein (GRA6) MGC-24 PF05283.11 GAX10857.1 - 0.01 16.3 0.5 0.016 15.7 0.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin BatD PF13584.6 GAX10857.1 - 0.031 13.1 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF5305 PF17231.2 GAX10857.1 - 0.04 13.3 0.0 0.082 12.3 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Toxin-JAB1 PF15659.6 GAX10857.1 - 0.11 12.8 1.3 0.44 10.9 0.0 2.5 3 1 0 3 3 3 0 JAB-like toxin 1 PT PF04886.12 GAX10857.1 - 1.6 8.4 17.6 1.7e+02 1.9 17.6 2.3 1 1 0 1 1 1 0 PT repeat Spore_coat_CotO PF14153.6 GAX10858.1 - 0.24 11.3 12.9 0.36 10.7 12.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TMEM214 PF10151.9 GAX10858.1 - 3.5 6.0 10.2 4.6 5.6 10.2 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Presenilin PF01080.17 GAX10858.1 - 5.7 5.6 10.9 7 5.3 10.9 1.1 1 0 0 1 1 1 0 Presenilin INCENP_ARK-bind PF03941.15 GAX10859.1 - 0.013 15.4 0.2 0.046 13.7 0.2 2.1 1 1 0 1 1 1 0 Inner centromere protein, ARK binding region Arrestin_N PF00339.29 GAX10860.1 - 0.00032 20.8 0.0 0.00099 19.2 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Mannitol_dh_C PF08125.13 GAX10862.1 - 0.011 15.2 0.1 3.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain CENP-B_dimeris PF09026.10 GAX10863.1 - 0.056 13.8 1.2 0.18 12.2 1.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_S30 PF01577.16 GAX10863.1 - 6.3 6.3 14.0 20 4.7 14.0 1.8 1 0 0 1 1 1 0 Potyvirus P1 protease NAD_binding_10 PF13460.6 GAX10864.1 - 5.6e-19 68.7 0.0 2.7e-09 37.2 0.0 3.0 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 GAX10864.1 - 4.2e-10 39.6 0.0 5.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 GAX10864.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX10864.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAX10864.1 - 0.0098 15.4 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.20 GAX10864.1 - 0.038 14.1 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 GAX10864.1 - 0.05 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAX10864.1 - 0.051 12.7 0.0 0.52 9.4 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein EccE PF11203.8 GAX10864.1 - 0.056 13.8 0.1 0.32 11.4 0.0 2.1 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE COX6B PF02297.17 GAX10865.1 - 4.7e-09 36.4 2.3 8.3e-09 35.6 2.3 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UQ_con PF00179.26 GAX10866.1 - 1.7e-26 92.6 0.0 2.4e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX10866.1 - 5.6e-07 29.3 0.0 8.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Prok-E2_A PF14457.6 GAX10866.1 - 0.025 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A RWD PF05773.22 GAX10866.1 - 0.064 13.6 2.1 0.13 12.5 2.2 1.5 1 1 0 1 1 1 0 RWD domain TPR_12 PF13424.6 GAX10867.1 - 5.5e-10 39.4 8.1 2.4e-07 30.9 2.8 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat SNAP PF14938.6 GAX10867.1 - 0.0023 17.4 0.3 0.0029 17.1 0.3 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 GAX10867.1 - 0.01 15.9 3.0 0.62 10.3 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX10867.1 - 0.037 13.9 2.3 1.2 9.0 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat HHH_8 PF14716.6 GAX10867.1 - 0.099 13.0 0.2 0.29 11.5 0.0 1.8 2 1 0 2 2 2 0 Helix-hairpin-helix domain TPR_7 PF13176.6 GAX10867.1 - 0.2 11.8 2.4 1.2 9.3 0.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 GAX10868.1 - 6.6e-47 159.8 0.0 7.6e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX10868.1 - 1.2e-12 48.9 0.0 1.6e-12 48.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX10868.1 - 1.3e-11 44.7 0.0 3e-08 33.6 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 GAX10868.1 - 1.7e-06 27.8 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 GAX10868.1 - 2.6e-06 27.5 0.1 8.4e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 GAX10868.1 - 0.014 14.9 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 GAX10868.1 - 0.02 14.6 0.1 0.035 13.8 0.1 1.4 1 1 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 GAX10868.1 - 0.043 13.8 0.2 0.075 13.0 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 GAX10868.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family FBPase PF00316.20 GAX10870.1 - 7e-33 113.7 0.0 1.7e-32 112.5 0.0 1.6 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain RSN1_7TM PF02714.15 GAX10871.1 - 6.1e-52 176.6 17.2 6.1e-52 176.6 17.2 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX10871.1 - 8.5e-32 110.1 1.6 8.5e-32 110.1 1.6 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX10871.1 - 6.5e-17 62.3 0.0 1.1e-11 45.3 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 GAX10872.1 - 4.5e-43 147.5 17.9 4.5e-43 147.5 17.9 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX10872.1 - 7.1e-34 116.8 1.0 7.1e-34 116.8 1.0 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX10872.1 - 1.4e-20 74.2 0.0 2.3e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PsbU PF06514.11 GAX10873.1 - 1e-32 111.9 0.2 1.5e-32 111.5 0.2 1.2 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 GAX10873.1 - 1.5e-05 25.2 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Aconitase_2_N PF06434.13 GAX10874.1 - 1.1e-90 302.7 0.0 1.8e-90 302.0 0.0 1.4 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 GAX10874.1 - 1.4e-57 194.1 0.9 2.6e-57 193.2 0.9 1.5 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 GAX10874.1 - 5.1e-42 144.4 0.0 3.4e-40 138.4 0.0 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Glyco_transf_90 PF05686.12 GAX10875.1 - 3.4e-14 52.6 0.1 6e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAX10875.1 - 0.014 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Phage_holin_5_1 PF06946.11 GAX10875.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 RSN1_7TM PF02714.15 GAX10876.1 - 6.8e-47 160.1 17.9 1.6e-46 158.9 17.9 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX10876.1 - 9.1e-35 119.7 1.1 9.1e-35 119.7 1.1 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX10876.1 - 8.6e-18 65.2 0.0 5.3e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 GAX10877.1 - 4.2e-48 164.0 21.7 4.6e-48 163.9 18.8 2.2 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX10877.1 - 9.7e-33 113.1 1.6 9.7e-33 113.1 1.6 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX10877.1 - 5.7e-18 65.7 1.7 8.7e-11 42.4 0.1 2.3 1 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter ProRS-C_1 PF09180.11 GAX10877.1 - 0.072 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal DUF563 PF04577.14 GAX10878.1 - 3.8e-17 63.1 0.0 5.5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 GAX10879.1 - 1.4e-15 58.0 0.0 2.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) zf-H3C2 PF16721.5 GAX10879.1 - 0.16 12.3 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding DUF2561 PF10812.8 GAX10880.1 - 0.0018 18.4 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) DUF1577 PF07614.11 GAX10880.1 - 0.05 12.7 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) Pterin_bind PF00809.22 GAX10883.1 - 1.9e-76 257.0 0.0 2.4e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 GAX10883.1 - 5.6e-37 126.7 0.0 1e-35 122.6 0.0 2.3 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) CactinC_cactus PF09732.9 GAX10884.1 - 5.8e-57 191.0 8.9 5.8e-57 191.0 8.9 2.1 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 GAX10884.1 - 4.9e-45 153.7 7.0 4.9e-45 153.7 7.0 1.9 2 0 0 2 2 2 1 Conserved mid region of cactin DUF4692 PF15763.5 GAX10884.1 - 0.096 13.2 13.1 0.19 12.2 13.1 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Zeta_toxin PF06414.12 GAX10885.1 - 7.1e-35 120.1 0.0 1.2e-23 83.5 0.0 2.9 2 1 1 3 3 3 2 Zeta toxin AAA_33 PF13671.6 GAX10885.1 - 8.2e-12 45.5 0.0 2.9e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX10885.1 - 1.8e-07 31.8 0.0 1e-06 29.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Microtub_bd PF16796.5 GAX10885.1 - 0.034 14.1 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding DUF1611 PF07755.11 GAX10885.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Kinesin PF00225.23 GAX10885.1 - 0.056 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain FtsJ PF01728.19 GAX10886.1 - 6.3e-65 218.6 0.0 7.7e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Myb_DNA-binding PF00249.31 GAX10887.1 - 1.5e-24 85.9 4.3 2.4e-12 46.9 0.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX10887.1 - 2.9e-19 69.0 4.3 5.7e-13 48.9 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX10887.1 - 3.4e-07 30.1 1.2 1e-06 28.5 0.3 2.1 2 0 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 GAX10887.1 - 2.8e-05 24.3 2.7 0.079 13.3 0.0 2.5 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GAX10887.1 - 0.0023 18.2 10.4 0.0048 17.2 0.9 2.7 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAX10887.1 - 0.088 13.0 0.4 0.45 10.8 0.1 2.1 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 GAX10887.1 - 9.9 6.3 11.7 8.6 6.5 0.5 3.7 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain NAP PF00956.18 GAX10888.1 - 1.8e-74 250.3 3.9 2.2e-74 250.0 3.9 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) ING PF12998.7 GAX10888.1 - 0.015 15.9 1.9 0.067 13.8 0.3 2.6 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding FCH PF00611.23 GAX10888.1 - 0.024 14.9 0.1 0.051 13.9 0.1 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DMAP_binding PF06464.11 GAX10888.1 - 0.11 13.3 0.2 0.11 13.3 0.2 1.6 2 0 0 2 2 2 0 DMAP1-binding Domain Ysc84 PF04366.12 GAX10889.1 - 1.2e-31 109.1 1.4 1.6e-31 108.7 0.1 1.9 2 0 0 2 2 2 1 Las17-binding protein actin regulator PDZ_6 PF17820.1 GAX10889.1 - 0.15 11.9 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 PDZ domain ADH_N PF08240.12 GAX10890.1 - 2.2e-31 107.9 0.2 2.2e-31 107.9 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAX10890.1 - 2.4e-27 95.5 0.6 4.3e-27 94.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAX10890.1 - 1.8e-05 25.8 0.0 3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAX10890.1 - 0.00012 21.7 0.2 0.00018 21.1 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 GAX10890.1 - 0.001 18.4 0.9 0.0016 17.8 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PglD_N PF17836.1 GAX10890.1 - 0.0021 18.7 0.2 0.0045 17.6 0.2 1.6 1 0 0 1 1 1 1 PglD N-terminal domain UDPG_MGDP_dh_N PF03721.14 GAX10890.1 - 0.017 14.7 0.4 0.025 14.2 0.4 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX10890.1 - 0.061 12.7 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAX10890.1 - 0.11 12.7 1.0 0.2 11.9 1.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAX10890.1 - 0.15 11.5 1.0 0.19 11.1 0.5 1.5 2 0 0 2 2 2 0 short chain dehydrogenase Glu_cyclase_2 PF05096.12 GAX10891.1 - 7.9e-73 245.0 0.2 9.9e-73 244.7 0.2 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase Cadherin_C_2 PF16492.5 GAX10892.1 - 1.8 9.3 4.2 5.5 7.8 0.0 3.0 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF3082 PF11282.8 GAX10893.1 - 0.083 13.1 3.6 1.7 9.0 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) B12D PF06522.11 GAX10893.1 - 0.13 12.0 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Yip1 PF04893.17 GAX10893.1 - 0.59 9.8 15.3 0.29 10.8 4.4 3.0 4 0 0 4 4 4 0 Yip1 domain Pox_EPC_I2-L1 PF12575.8 GAX10893.1 - 3.9 7.8 7.8 31 4.9 0.2 3.9 3 1 1 4 4 4 0 Poxvirus entry protein complex L1 and I2 FBPase PF00316.20 GAX10894.1 - 1.1e-44 152.2 0.0 1.8e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 GAX10894.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family WD40 PF00400.32 GAX10895.1 - 6.5e-11 42.6 12.9 0.0048 17.7 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX10895.1 - 8.3e-08 32.4 0.4 0.068 13.5 0.0 4.7 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome PF00227.26 GAX10896.1 - 0.00053 19.5 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit DUF2046 PF09755.9 GAX10897.1 - 1.3e-11 44.3 18.4 1.7e-11 43.9 18.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF2570 PF10828.8 GAX10897.1 - 3.3 7.6 10.1 0.2 11.5 2.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) ABC_ATPase PF09818.9 GAX10899.1 - 4.5e-103 345.4 0.1 6.5e-83 279.0 0.1 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 GAX10899.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX10899.1 - 0.11 13.0 1.5 0.23 11.9 0.1 2.2 3 0 0 3 3 3 0 AAA domain TetR_C_14 PF17754.1 GAX10899.1 - 0.15 12.0 0.4 0.33 10.9 0.4 1.5 1 0 0 1 1 1 0 MftR C-terminal domain bZIP_1 PF00170.21 GAX10903.1 - 2.1e-06 27.7 13.7 5.2e-06 26.5 13.7 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX10903.1 - 0.0076 16.3 3.2 0.0076 16.3 3.2 4.1 3 1 1 4 4 4 2 Basic region leucine zipper Atg14 PF10186.9 GAX10903.1 - 0.25 10.4 8.3 0.42 9.6 8.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF148 PF02520.17 GAX10903.1 - 0.26 11.4 4.5 0.32 11.1 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 MFMR_assoc PF16596.5 GAX10903.1 - 2.5 8.5 11.8 0.48 10.9 7.8 1.9 2 0 0 2 2 2 0 Disordered region downstream of MFMR Peptidase_C1 PF00112.23 GAX10904.1 - 2.3e-33 116.1 0.1 6e-24 85.3 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX10904.1 - 8.5e-06 26.1 0.3 8.5e-06 26.1 0.3 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) DUF179 PF02622.15 GAX10904.1 - 0.03 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1678 NDUFB10 PF10249.9 GAX10905.1 - 5.7e-06 26.9 0.5 6.4e-06 26.7 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF676 PF05057.14 GAX10906.1 - 1.3e-26 93.5 0.0 6.9e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GAX10906.1 - 0.00033 20.6 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 GAX10906.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Cys_Met_Meta_PP PF01053.20 GAX10907.1 - 3.9e-126 420.6 0.0 4.4e-126 420.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAX10907.1 - 2.1e-07 30.4 0.0 2.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAX10907.1 - 7.2e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAX10907.1 - 2.3e-05 23.6 0.0 3.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Peptidase_S9 PF00326.21 GAX10907.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family AIG2_2 PF13772.6 GAX10908.1 - 2.7e-06 27.7 0.0 4.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family MatE PF01554.18 GAX10910.1 - 8.6e-24 84.0 23.5 1.3e-19 70.4 8.8 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAX10910.1 - 1.2e-05 25.4 5.8 1.2e-05 25.4 5.8 3.8 4 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain EF-hand_1 PF00036.32 GAX10911.1 - 9.2e-10 37.4 1.9 2.6e-05 23.4 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX10911.1 - 2e-09 36.6 0.6 0.00032 20.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX10911.1 - 3e-09 36.0 1.9 0.0003 20.2 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAX10911.1 - 7.6e-07 29.5 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX10911.1 - 2.5e-05 24.0 0.9 0.00043 20.1 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair G10 PF01125.17 GAX10913.1 - 9.5e-53 177.9 3.2 1.7e-52 177.0 3.2 1.4 1 0 0 1 1 1 1 G10 protein Trypan_PARP PF05887.11 GAX10913.1 - 2.1 8.3 10.6 3.5 7.6 10.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Adeno_E3_CR2 PF02439.15 GAX10914.1 - 0.032 14.0 0.2 0.073 12.8 0.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pelovaterin PF17859.1 GAX10914.1 - 0.085 13.1 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Pelovaterin Methyltransf_11 PF08241.12 GAX10915.1 - 1.2e-15 58.0 0.0 3.2e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX10915.1 - 5.5e-14 52.6 0.1 4.1e-13 49.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Mem_trans PF03547.18 GAX10915.1 - 1.1e-13 50.4 0.1 2.3e-13 49.3 0.1 1.5 1 1 0 1 1 1 1 Membrane transport protein Methyltransf_23 PF13489.6 GAX10915.1 - 5.5e-09 36.1 0.0 1.6e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX10915.1 - 1.6e-07 31.2 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAX10915.1 - 6.2e-07 30.1 0.0 2.4e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX10915.1 - 2.5e-06 27.0 0.0 5.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAX10915.1 - 4.4e-05 23.4 0.0 0.0073 16.2 0.0 2.2 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 GAX10915.1 - 0.00077 19.1 0.1 0.35 10.4 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_2 PF00891.18 GAX10915.1 - 0.00093 18.5 0.2 0.013 14.8 0.0 2.7 3 1 0 3 3 3 1 O-methyltransferase domain Methyltransf_4 PF02390.17 GAX10915.1 - 0.17 11.3 0.0 0.75 9.2 0.0 2.1 3 0 0 3 3 3 0 Putative methyltransferase Sec8_exocyst PF04048.14 GAX10916.1 - 0.00021 21.2 6.0 0.0013 18.7 0.7 3.4 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain NUDIX PF00293.28 GAX10917.1 - 8.8e-09 35.5 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pneumovirus_M2 PF06436.11 GAX10919.1 - 0.0053 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Pneumovirus matrix protein 2 (M2) DDE_Tnp_4 PF13359.6 GAX10920.1 - 4.5e-08 32.9 0.0 8.9e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease MADF_DNA_bdg PF10545.9 GAX10920.1 - 0.1 12.9 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HTH_Tnp_4 PF13613.6 GAX10920.1 - 0.11 12.2 0.3 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HSP20 PF00011.21 GAX10921.1 - 4.8e-18 65.2 0.5 7e-18 64.7 0.5 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 GAX10921.1 - 0.012 16.6 0.1 0.019 16.0 0.1 1.4 1 0 0 1 1 1 0 CS domain ArsA_HSP20 PF17886.1 GAX10921.1 - 0.016 14.7 0.1 0.037 13.6 0.1 1.6 1 1 0 1 1 1 0 HSP20-like domain found in ArsA GvpH PF05455.11 GAX10921.1 - 0.037 14.1 0.6 0.083 13.0 0.6 1.5 1 1 0 1 1 1 0 GvpH SPX PF03105.19 GAX10922.1 - 3.5e-18 66.7 22.5 4.3e-10 40.1 12.5 2.8 1 1 1 2 2 2 2 SPX domain CTP_transf_like PF01467.26 GAX10922.1 - 9.2e-09 35.6 0.0 3.8e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 GAX10922.1 - 0.005 16.7 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD synthetase Sec3_C PF09763.9 GAX10922.1 - 0.095 11.1 5.9 0.13 10.6 5.9 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Asp_protease_2 PF13650.6 GAX10923.1 - 9.4e-12 45.4 2.3 2.3e-06 28.2 0.0 2.8 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 GAX10923.1 - 4.2e-11 43.3 1.4 3.4e-06 27.5 0.3 3.3 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GAX10923.1 - 0.00054 19.8 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GAX10923.1 - 0.0015 18.8 0.7 0.0064 16.8 0.2 2.3 3 0 0 3 3 3 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 GAX10923.1 - 0.18 11.4 0.1 0.8 9.2 0.0 1.9 2 0 0 2 2 2 0 Ty3 transposon peptidase Exostosin PF03016.15 GAX10924.1 - 1.2e-26 93.7 0.1 4.4e-26 91.8 0.1 1.9 1 1 0 1 1 1 1 Exostosin family Podoplanin PF05808.11 GAX10926.1 - 3.2 7.8 11.7 5.6 7.1 11.7 1.3 1 0 0 1 1 1 0 Podoplanin HSP9_HSP12 PF04119.12 GAX10927.1 - 1.8e-08 34.6 66.5 0.00065 20.0 2.4 9.8 7 4 2 9 9 9 6 Heat shock protein 9/12 SMBP PF16785.5 GAX10927.1 - 0.0017 18.6 11.6 0.32 11.2 0.1 4.5 2 1 3 5 5 5 2 Small metal-binding protein DUF4777 PF16007.5 GAX10927.1 - 0.061 13.6 0.2 12 6.3 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4777) HTH_41 PF14502.6 GAX10927.1 - 0.33 10.7 2.9 27 4.6 0.0 3.8 4 0 0 4 4 4 0 Helix-turn-helix domain DUF883 PF05957.13 GAX10929.1 - 8.4e-14 52.0 60.6 0.0015 19.1 5.8 7.2 2 1 5 7 7 7 6 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 GAX10929.1 - 5.8e-13 49.1 52.7 8.9e-07 29.0 19.6 4.0 1 1 3 4 4 4 4 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GAX10929.1 - 1.3e-10 41.7 89.2 0.012 16.1 6.5 8.3 2 1 5 7 7 7 5 YtxH-like protein LEA_4 PF02987.16 GAX10929.1 - 1.8e-10 40.7 118.8 0.00022 21.3 4.8 9.9 3 1 7 11 11 11 8 Late embryogenesis abundant protein DUF842 PF05811.13 GAX10929.1 - 1.1e-05 25.2 28.4 0.057 13.1 7.2 4.5 1 1 3 4 4 4 4 Eukaryotic protein of unknown function (DUF842) ApoLp-III PF07464.11 GAX10929.1 - 0.2 11.7 60.3 0.05 13.7 14.3 4.4 1 1 4 5 5 5 0 Apolipophorin-III precursor (apoLp-III) HisKA_3 PF07730.13 GAX10929.1 - 0.4 11.2 25.3 26 5.4 0.1 7.7 4 1 2 6 6 6 0 Histidine kinase ApoO PF09769.9 GAX10929.1 - 0.41 10.6 36.1 7.4 6.5 1.2 7.0 1 1 2 3 3 2 0 Apolipoprotein O Prominin PF05478.11 GAX10929.1 - 1 7.2 24.3 1 7.3 22.9 1.7 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 GAX10929.1 - 1.1 9.3 34.8 0.037 14.0 5.9 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Mitofilin PF09731.9 GAX10929.1 - 1.9 7.2 81.8 2 7.2 28.9 3.0 1 1 2 3 3 3 0 Mitochondrial inner membrane protein YbjQ_1 PF01906.17 GAX10929.1 - 2.3 8.9 18.1 3.7 8.2 0.7 4.8 2 1 2 5 5 5 0 Putative heavy-metal-binding PRESAN PF09687.10 GAX10929.1 - 7.4 7.2 9.7 2.2 8.9 0.7 2.9 2 1 0 2 2 2 0 Plasmodium RESA N-terminal DUF2817 PF10994.8 GAX10930.1 - 3.5e-68 230.5 0.0 4.2e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 GAX10930.1 - 0.057 12.5 0.2 0.11 11.5 0.1 1.5 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Lipase_GDSL_2 PF13472.6 GAX10931.1 - 1e-16 61.9 0.1 2.8e-16 60.4 0.1 1.7 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX10931.1 - 1.7e-07 31.5 0.0 4e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TPR_14 PF13428.6 GAX10932.1 - 1.3e-09 38.0 19.2 3.2 8.8 0.0 11.5 8 3 5 13 13 13 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX10932.1 - 4.8e-05 22.9 4.0 0.00043 19.8 2.6 2.8 1 1 1 2 2 2 1 MalT-like TPR region TPR_15 PF13429.6 GAX10932.1 - 7.9e-05 22.0 16.7 0.0016 17.7 0.0 5.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX10932.1 - 0.00051 20.5 7.1 17 6.0 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX10932.1 - 0.0058 16.9 2.8 1.4 9.3 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF4080 PF13311.6 GAX10932.1 - 0.044 14.0 1.2 6.2 7.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4080) TPR_17 PF13431.6 GAX10932.1 - 0.059 13.8 3.0 9.8 6.8 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAX10932.1 - 0.37 10.8 15.5 1.6 8.7 0.0 6.1 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 GAX10932.1 - 0.91 10.2 8.0 1.6 9.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX10932.1 - 8.8 7.3 7.3 62 4.7 0.5 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4282 PF14110.6 GAX10933.1 - 0.14 12.9 0.8 0.18 12.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) UCH PF00443.29 GAX10934.1 - 1e-68 231.6 0.0 1.8e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX10934.1 - 1.2e-19 71.1 0.1 3e-14 53.4 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_2 PF13240.6 GAX10934.1 - 0.027 14.2 1.7 5.2 6.9 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain PCB_OB PF17092.5 GAX10934.1 - 0.06 14.1 0.1 0.15 12.9 0.1 1.6 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain Dus PF01207.17 GAX10936.1 - 1.6e-55 188.4 0.0 3.7e-55 187.2 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Hydrolase_6 PF13344.6 GAX10936.1 - 0.00052 20.1 0.0 0.015 15.4 0.0 2.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase zf-CCCH_3 PF15663.5 GAX10936.1 - 0.014 15.6 2.4 0.024 14.8 1.1 2.0 2 0 0 2 2 2 0 Zinc-finger containing family DHO_dh PF01180.21 GAX10936.1 - 0.2 10.8 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF3682 PF12446.8 GAX10936.1 - 3.1 8.3 5.6 5.9 7.4 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Ank_2 PF12796.7 GAX10937.1 - 1.1e-29 102.9 0.0 8.5e-08 32.7 0.0 6.7 3 3 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX10937.1 - 2.9e-24 82.5 9.4 0.026 15.0 0.1 11.0 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 GAX10937.1 - 1.7e-21 76.0 3.1 0.081 13.3 0.0 9.1 6 2 4 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 GAX10937.1 - 2.8e-19 68.6 4.1 0.13 12.8 0.0 9.2 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 GAX10937.1 - 6.5e-14 52.1 5.8 0.008 16.7 0.1 8.6 7 3 2 9 9 9 4 Ankyrin repeats (many copies) GATase_7 PF13537.6 GAX10937.1 - 0.045 13.7 0.0 0.6 10.0 0.0 2.8 4 0 0 4 4 4 0 Glutamine amidotransferase domain Inositol_P PF00459.25 GAX10938.1 - 1.4e-31 110.1 0.0 1.2e-30 106.9 0.0 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Molybdopterin PF00384.22 GAX10938.1 - 0.083 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Nipped-B_C PF12830.7 GAX10939.1 - 2e-37 129.0 0.0 1.4e-34 119.7 0.0 3.2 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 GAX10939.1 - 3.8e-10 39.9 0.7 7.7e-07 29.3 0.5 3.2 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 GAX10939.1 - 1.6e-05 25.2 0.1 0.098 13.1 0.1 3.5 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 GAX10939.1 - 4.7e-05 23.3 0.4 1.1 9.7 0.0 5.9 6 0 0 6 6 5 1 HEAT repeat API5 PF05918.11 GAX10939.1 - 0.00028 19.8 1.5 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 Apoptosis inhibitory protein 5 (API5) HEAT_EZ PF13513.6 GAX10939.1 - 0.0014 19.1 0.0 0.018 15.5 0.0 3.1 2 0 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 GAX10939.1 - 0.0014 18.7 0.3 0.021 14.9 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 GAX10939.1 - 0.006 15.8 1.6 0.012 14.9 0.1 2.2 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 GAX10939.1 - 0.019 13.5 2.6 0.29 9.6 0.2 3.1 4 0 0 4 4 4 0 Adaptin N terminal region RTTN_N PF14726.6 GAX10939.1 - 0.023 15.5 0.3 2.6 8.9 0.0 3.2 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning PHD_2 PF13831.6 GAX10939.1 - 0.024 14.2 10.2 0.025 14.1 8.3 2.0 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 GAX10939.1 - 0.028 14.3 14.1 0.07 13.0 14.1 1.7 1 0 0 1 1 1 0 PHD-finger CLASP_N PF12348.8 GAX10939.1 - 0.077 12.5 0.1 9.4 5.7 0.0 3.0 2 1 1 3 3 3 0 CLASP N terminal TFIIB PF00382.19 GAX10940.1 - 7e-35 118.9 3.2 5.4e-19 68.0 0.2 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GAX10940.1 - 2.6e-16 59.8 5.3 8.1e-16 58.2 5.3 1.8 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 GAX10940.1 - 2.2e-09 36.7 0.6 4.9e-09 35.6 0.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 GAX10940.1 - 8.7e-06 25.5 0.5 0.042 13.6 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Lar_restr_allev PF14354.6 GAX10940.1 - 0.14 12.6 0.4 0.59 10.5 0.4 2.1 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf_Rg PF17915.1 GAX10940.1 - 0.26 10.7 0.5 0.55 9.7 0.5 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger zf-ribbon_3 PF13248.6 GAX10940.1 - 0.68 9.4 2.2 5.7 6.5 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 GAX10940.1 - 2.1 8.4 5.6 17 5.5 5.3 2.3 1 1 1 2 2 2 0 YhfH-like protein ALMT PF11744.8 GAX10940.1 - 7.4 5.3 6.3 11 4.7 6.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Ank_2 PF12796.7 GAX10941.1 - 2.8e-18 66.3 0.0 9e-11 42.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX10941.1 - 1.5e-11 43.4 0.2 0.0057 17.1 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAX10941.1 - 3.1e-11 43.2 1.1 0.039 14.4 0.0 4.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAX10941.1 - 2e-10 40.7 0.0 2.2e-05 24.6 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX10941.1 - 5.7e-10 39.5 0.1 0.096 13.3 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) MIF4G PF02854.19 GAX10942.1 - 1.3e-33 116.5 0.1 8.3e-15 55.0 0.0 4.4 4 0 0 4 4 4 4 MIF4G domain Upf2 PF04050.14 GAX10942.1 - 2e-13 51.2 4.4 2e-13 51.2 4.4 3.2 2 0 0 2 2 2 1 Up-frameshift suppressor 2 DUF677 PF05055.12 GAX10942.1 - 0.049 12.5 12.8 0.14 11.1 12.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF677) RPW8 PF05659.11 GAX10942.1 - 0.17 11.5 5.0 0.52 10.0 1.4 2.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4085 PF13315.6 GAX10942.1 - 0.75 9.4 5.6 2.1 8.0 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF1993 PF09351.10 GAX10942.1 - 7.2 6.7 7.2 6.4 6.9 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) RIO1 PF01163.22 GAX10943.1 - 2.6e-70 235.9 0.1 2.6e-70 235.9 0.1 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 GAX10943.1 - 0.0001 22.3 0.2 0.00084 19.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX10943.1 - 0.0016 17.3 0.0 0.0016 17.3 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase HSF_DNA-bind PF00447.17 GAX10944.1 - 3.7e-17 62.7 0.9 6.2e-17 62.0 0.0 1.8 2 1 1 3 3 3 1 HSF-type DNA-binding Sacchrp_dh_C PF16653.5 GAX10946.1 - 1.5e-74 251.4 0.0 3e-74 250.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 GAX10946.1 - 4.5e-22 78.8 0.0 1.2e-21 77.5 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 GAX10946.1 - 6.6e-17 62.0 0.0 1.9e-16 60.5 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Saccharop_dh_N PF04455.12 GAX10946.1 - 3.8e-05 24.0 0.2 0.00013 22.3 0.0 2.0 2 0 0 2 2 2 1 LOR/SDH bifunctional enzyme conserved region AlaDh_PNT_C PF01262.21 GAX10946.1 - 0.00067 19.0 0.0 0.013 14.8 0.0 2.5 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 GAX10946.1 - 0.01 15.9 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pro_isomerase PF00160.21 GAX10948.1 - 6.3e-51 172.8 0.0 1e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GAX10948.1 - 6.2e-09 36.3 3.1 0.018 15.9 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX10948.1 - 0.00029 21.1 0.1 1.4 9.3 0.0 3.9 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 GAX10948.1 - 0.066 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Nucleoporin_N PF08801.11 GAX10948.1 - 0.11 11.2 0.3 3.9 6.1 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Ank_4 PF13637.6 GAX10949.1 - 9.4e-09 35.6 0.1 0.00042 20.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX10949.1 - 7.4e-06 26.5 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX10949.1 - 0.00077 19.7 0.0 0.0037 17.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX10949.1 - 0.0065 16.9 0.0 0.26 11.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat LAT PF15234.6 GAX10949.1 - 0.063 13.0 3.6 0.1 12.3 3.6 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Ank PF00023.30 GAX10949.1 - 0.11 13.0 0.0 29 5.3 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeat GCIP PF13324.6 GAX10949.1 - 0.12 12.0 5.8 0.22 11.1 5.8 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM176 PF14851.6 GAX10949.1 - 0.52 10.0 6.2 0.52 10.0 1.7 2.2 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 GAX10949.1 - 1.1 9.3 9.8 0.29 11.2 4.6 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 GAX10949.1 - 1.9 7.8 19.5 0.2 10.9 13.1 2.1 2 0 0 2 2 2 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAX10949.1 - 3.9 7.1 20.4 0.38 10.4 13.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 GAX10949.1 - 5.1 6.1 21.7 0.14 11.3 14.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) FYDLN_acid PF09538.10 GAX10949.1 - 5.7 7.7 18.1 2.8 8.7 12.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 GAX10949.1 - 6.7 4.7 18.7 11 4.0 18.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GAX10949.1 - 7.2 4.8 11.8 0.35 9.1 4.4 1.9 2 0 0 2 2 2 0 CDC45-like protein ECH_1 PF00378.20 GAX10950.1 - 2.5e-48 164.6 0.0 2.5e-48 164.6 0.0 2.6 3 1 1 4 4 4 1 Enoyl-CoA hydratase/isomerase CAF1A PF12253.8 GAX10950.1 - 8.5e-25 86.7 11.7 8.5e-25 86.7 11.7 3.8 3 2 1 4 4 4 1 Chromatin assembly factor 1 subunit A ECH_2 PF16113.5 GAX10950.1 - 8.6e-13 48.5 0.0 8.6e-13 48.5 0.0 2.4 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ATP-synt_F PF01990.17 GAX10950.1 - 0.11 12.8 0.1 0.42 11.0 0.1 2.0 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit DOT1 PF08123.13 GAX10951.1 - 0.1 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Nuc_N PF14448.6 GAX10952.1 - 0.14 12.0 4.4 0.66 9.9 0.1 4.1 3 0 0 3 3 3 0 Nuclease N terminal SseC PF04888.12 GAX10953.1 - 0.024 14.3 0.3 0.03 13.9 0.3 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Redoxin PF08534.10 GAX10954.1 - 3.1e-22 78.9 0.0 3.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAX10954.1 - 1.2e-08 34.9 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Cuticle_3 PF11018.8 GAX10955.1 - 0.052 13.8 7.4 0.07 13.3 7.4 1.3 1 0 0 1 1 1 0 Pupal cuticle protein C1 NOG1_N PF17835.1 GAX10955.1 - 0.063 13.2 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Ribosomal_L13 PF00572.18 GAX10956.1 - 1e-51 174.4 0.1 1.4e-51 174.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 DUF5320 PF17253.2 GAX10957.1 - 0.032 15.3 1.3 0.071 14.2 1.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Sec3_C_2 PF15278.6 GAX10957.1 - 0.47 10.8 3.1 0.49 10.8 0.6 2.1 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Pkinase PF00069.25 GAX10958.1 - 3.7e-67 226.5 0.0 6e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10958.1 - 3.7e-28 98.5 0.0 6.5e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAX10958.1 - 3.6e-11 43.2 0.0 8.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 GAX10958.1 - 0.00012 21.0 0.0 0.00031 19.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAX10958.1 - 0.0031 16.9 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GAX10958.1 - 0.0044 16.6 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAX10958.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GDI PF00996.18 GAX10959.1 - 4.4e-181 602.2 0.0 7.4e-181 601.4 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor Glutaminase PF04960.15 GAX10959.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Glutaminase VDE PF07137.11 GAX10961.1 - 4e-92 308.1 0.7 6.3e-92 307.4 0.7 1.3 1 0 0 1 1 1 1 VDE lipocalin domain Tail_P2_I PF09684.10 GAX10962.1 - 0.08 12.9 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) IGPS PF00218.21 GAX10963.1 - 3.6e-25 88.6 0.0 1.1e-24 87.0 0.0 1.8 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase FIST PF08495.10 GAX10963.1 - 5.4e-11 42.8 1.6 2.6e-10 40.6 0.1 2.6 3 1 0 3 3 3 1 FIST N domain DUF4611 PF15387.6 GAX10963.1 - 0.043 14.0 7.3 0.036 14.3 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) E7 PF00527.18 GAX10963.1 - 1 9.6 5.9 0.086 13.0 0.9 1.8 2 0 0 2 2 2 0 E7 protein, Early protein Metallophos PF00149.28 GAX10964.1 - 4.4e-33 115.5 0.2 6.2e-33 115.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ThiF PF00899.21 GAX10964.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 ThiF family Toxin_29 PF08116.11 GAX10965.1 - 0.5 10.4 9.1 0.29 11.2 2.7 2.8 2 0 0 2 2 2 0 PhTx neurotoxin family EGF_2 PF07974.13 GAX10965.1 - 1.2 9.5 37.2 2 8.9 7.8 5.1 3 3 0 3 3 3 0 EGF-like domain MS_channel PF00924.18 GAX10966.1 - 2.4e-14 53.4 0.6 4.5e-14 52.5 0.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Thioredoxin PF00085.20 GAX10967.1 - 3.5e-20 71.9 0.3 4.6e-20 71.5 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 GAX10967.1 - 5.2e-06 26.4 0.1 8.3e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 GAX10967.1 - 5.7e-05 23.5 0.6 0.0019 18.7 0.6 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GAX10967.1 - 0.0012 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GAX10967.1 - 0.0066 16.6 0.2 0.011 15.9 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX10967.1 - 0.012 16.0 0.4 2.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX10967.1 - 0.019 14.7 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin Herpes_UL56 PF04534.12 GAX10967.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 Herpesvirus UL56 protein AhpC-TSA PF00578.21 GAX10967.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Cullin_binding PF03556.15 GAX10968.1 - 2e-23 83.1 0.3 2e-23 83.1 0.3 1.5 2 0 0 2 2 2 1 Cullin binding FG-GAP_2 PF14312.6 GAX10969.1 - 9.8e-61 201.8 31.7 1.2e-12 47.8 0.3 8.1 7 2 0 7 7 7 7 FG-GAP repeat HisK_sensor PF18698.1 GAX10969.1 - 9.1e-05 22.8 0.2 2.4 8.5 0.0 4.2 4 0 0 4 4 4 2 Histidine kinase sensor domain Kelch_3 PF13415.6 GAX10969.1 - 0.01 16.1 1.5 4.7 7.6 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain PQQ_3 PF13570.6 GAX10969.1 - 0.27 11.8 11.2 0.63 10.6 0.1 5.2 6 0 0 6 6 6 0 PQQ-like domain Kelch_4 PF13418.6 GAX10969.1 - 1 9.5 4.8 92 3.2 0.1 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain SET PF00856.28 GAX10971.1 - 2.6e-08 34.4 0.0 5.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 SET domain PSD2 PF07624.11 GAX10972.1 - 0.15 11.9 0.5 2.2 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Arg_decarbox_C PF17944.1 GAX10973.1 - 0.18 12.4 0.0 0.4 11.3 0.0 1.6 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension AAA PF00004.29 GAX10974.1 - 3.5e-06 27.5 0.4 2.6e-05 24.6 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX10974.1 - 0.00019 21.7 0.0 0.00072 19.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIG PF01833.24 GAX10974.1 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain Adeno_IVa2 PF02456.15 GAX10974.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 GAX10974.1 - 0.041 13.8 0.2 0.29 11.0 0.0 2.4 1 1 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 GAX10974.1 - 0.056 13.4 0.0 0.58 10.0 0.0 2.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAX10974.1 - 0.097 13.0 0.0 0.35 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain zf-RanBP PF00641.18 GAX10974.1 - 0.2 11.0 4.6 0.46 9.9 4.6 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others ThylakoidFormat PF11264.8 GAX10974.1 - 0.83 9.3 9.0 2.6 7.7 1.5 3.2 2 1 1 3 3 3 0 Thylakoid formation protein Complex1_51K PF01512.17 GAX10975.1 - 9.4e-50 168.4 0.0 1.3e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GAX10975.1 - 6.3e-30 103.1 0.0 1.1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GAX10975.1 - 2.5e-09 36.8 0.0 5.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 SLBB domain PsbP PF01789.16 GAX10976.1 - 0.081 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 PsbP Pkinase PF00069.25 GAX10977.1 - 1.1e-64 218.4 0.0 1.7e-64 217.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10977.1 - 2.7e-34 118.7 0.0 4.7e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX10977.1 - 1.8e-10 41.1 2.2 0.00041 20.7 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX10977.1 - 3.8e-09 35.5 1.4 0.0092 15.5 0.1 4.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 GAX10977.1 - 9.1e-09 34.6 3.4 0.0084 16.0 0.0 4.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.6 GAX10977.1 - 5e-06 25.8 1.8 0.092 12.3 0.0 3.6 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 GAX10977.1 - 1.2e-05 24.9 0.0 0.00017 21.0 0.1 2.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 GAX10977.1 - 2.3e-05 23.9 0.1 4.8e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX10977.1 - 3.3e-05 22.8 0.1 0.0002 20.3 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAX10977.1 - 0.0018 18.2 0.1 0.0045 16.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family tRNA-synt_2b PF00587.25 GAX10978.1 - 1.5e-35 122.8 0.0 3.9e-35 121.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAX10978.1 - 1.4e-18 66.8 0.7 1.4e-18 66.8 0.7 1.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 GAX10978.1 - 3.6e-11 43.0 0.0 8.3e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 GAX10978.1 - 3e-06 27.2 0.0 6.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain Trigger_N PF05697.13 GAX10979.1 - 2.9e-08 34.2 0.1 4.4e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) PRKCSH_1 PF13015.6 GAX10980.1 - 5.5e-28 97.6 0.2 1e-27 96.7 0.2 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 GAX10980.1 - 2.7e-16 59.9 6.5 1.2e-15 57.8 6.4 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH PF07915.13 GAX10980.1 - 0.0018 19.3 0.7 0.0057 17.6 0.7 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Unstab_antitox PF09720.10 GAX10980.1 - 0.0022 18.0 3.2 0.14 12.2 0.1 3.3 3 0 0 3 3 3 1 Putative addiction module component ABC_tran_CTD PF16326.5 GAX10980.1 - 0.19 12.0 3.9 0.32 11.3 0.4 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain CLZ PF16526.5 GAX10980.1 - 0.19 12.1 3.7 1.7 9.1 0.4 2.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 GAX10980.1 - 0.98 9.4 10.4 5.6 7.0 0.8 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 mTERF PF02536.14 GAX10981.1 - 9.1e-41 139.8 0.3 1.5e-25 89.8 0.0 4.1 3 1 1 4 4 4 4 mTERF HTH_ParB PF17762.1 GAX10981.1 - 0.37 10.6 2.5 4.7 7.1 1.4 2.6 2 0 0 2 2 2 0 HTH domain found in ParB protein MGDG_synth PF06925.11 GAX10983.1 - 1.1e-20 74.4 0.0 1.7e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 GAX10983.1 - 2.9e-10 40.4 0.0 7.2e-09 35.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 GAX10983.1 - 0.08 13.4 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferases group 1 DUF1179 PF06678.11 GAX10984.1 - 0.47 10.5 5.2 9.3 6.3 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) Raptor_N PF14538.6 GAX10985.1 - 7.1e-51 172.0 0.0 1.2e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 GAX10985.1 - 2.5e-07 31.2 6.5 1.1 10.2 0.2 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.22 GAX10985.1 - 0.004 17.3 1.0 0.23 11.8 0.1 3.9 4 0 0 4 4 4 1 HEAT repeat ANAPC4_WD40 PF12894.7 GAX10985.1 - 0.035 14.4 0.1 84 3.6 0.0 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Glycos_transf_1 PF00534.20 GAX10986.1 - 4.8e-34 117.4 0.0 7.1e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX10986.1 - 2.3e-29 102.5 0.0 4.1e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX10986.1 - 4.4e-18 65.9 2.4 2.4e-17 63.5 3.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAX10986.1 - 5e-12 46.5 1.8 7.4e-12 46.0 0.3 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX10986.1 - 1.5e-10 41.3 0.0 3.9e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 GNT-I PF03071.15 GAX10987.1 - 0.2 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 GNT-I family SNARE_assoc PF09335.11 GAX10988.1 - 1e-21 77.7 9.2 1.3e-19 70.9 8.3 2.3 1 1 1 2 2 2 2 SNARE associated Golgi protein DUF1151 PF06625.11 GAX10988.1 - 0.0063 16.4 1.4 0.01 15.7 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) KRTAP7 PF15034.6 GAX10988.1 - 0.092 13.7 0.5 0.62 11.1 0.1 2.1 2 0 0 2 2 2 0 KRTAP type 7 family DUF3169 PF11368.8 GAX10988.1 - 0.16 11.4 1.0 0.28 10.6 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF2368 PF10166.9 GAX10988.1 - 4.9 6.8 5.3 0.95 9.1 0.1 2.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2368) Herpes_US9 PF06072.11 GAX10989.1 - 0.11 12.4 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ETRAMP PF09716.10 GAX10989.1 - 0.18 11.9 0.0 0.47 10.6 0.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ion_trans PF00520.31 GAX10990.1 - 3e-37 128.2 28.7 4.1e-37 127.7 28.7 1.1 1 0 0 1 1 1 1 Ion transport protein DUF4834 PF16118.5 GAX10990.1 - 0.33 11.9 0.0 0.33 11.9 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF5313 PF17240.2 GAX10990.1 - 10 6.6 7.5 0.49 10.8 0.8 2.2 2 1 1 3 3 3 0 Family of unknown function (DUF5313) LRR_8 PF13855.6 GAX10991.1 - 9.6e-26 89.3 18.7 2.4e-11 43.2 1.0 5.0 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 GAX10991.1 - 7.2e-18 64.4 22.4 1.2e-06 28.7 3.4 5.3 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX10991.1 - 2.7e-09 36.3 14.7 0.079 13.6 0.1 8.2 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_9 PF14580.6 GAX10991.1 - 5.2e-08 32.6 8.6 6e-05 22.6 1.0 3.1 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 GAX10991.1 - 0.0044 17.0 24.6 0.69 10.1 0.2 7.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_2 PF07723.13 GAX10991.1 - 2.1 9.1 5.7 84 4.1 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat Gemini_mov PF01708.16 GAX10992.1 - 0.14 12.0 2.1 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein EphA2_TM PF14575.6 GAX10992.1 - 0.3 12.0 1.1 3.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Diphthamide_syn PF01866.17 GAX10993.1 - 6.6e-70 235.9 0.0 8.5e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein NnrU PF07298.11 GAX10994.1 - 3.9e-09 36.3 0.1 8.1e-08 32.0 0.1 2.1 1 1 0 1 1 1 1 NnrU protein Pkinase PF00069.25 GAX10995.1 - 8.7e-29 100.7 0.0 3.4e-28 98.7 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX10995.1 - 4.2e-27 95.1 0.0 1.1e-26 93.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pro_isomerase PF00160.21 GAX10996.1 - 1.1e-44 152.5 0.2 1.4e-44 152.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GYF PF02213.16 GAX10997.1 - 2.8e-16 58.9 0.4 5.4e-16 58.0 0.4 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 GAX10997.1 - 0.0026 17.5 0.2 0.008 16.0 0.2 1.9 1 0 0 1 1 1 1 GYF domain 2 DUF1415 PF07209.12 GAX10998.1 - 2.4e-40 138.1 0.0 3.8e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) IPP-2 PF04979.14 GAX10998.1 - 0.021 15.6 0.5 0.044 14.5 0.5 1.6 1 1 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Ribosomal_L7Ae PF01248.26 GAX11000.1 - 1.2e-23 82.6 0.1 1.3e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 GAX11000.1 - 0.0065 16.6 0.0 0.0076 16.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF521 PF04412.13 GAX11000.1 - 0.013 14.3 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) His_Phos_1 PF00300.22 GAX11004.1 - 1.3e-36 126.1 0.1 1.6e-36 125.8 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SUKH-3 PF14433.6 GAX11004.1 - 0.032 14.7 0.0 0.045 14.2 0.0 1.2 1 0 0 1 1 1 0 SUKH-3 immunity protein Lipase_3 PF01764.25 GAX11005.1 - 0.0019 18.0 0.2 0.011 15.6 0.2 2.3 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAX11005.1 - 0.028 14.0 0.9 6.4 6.3 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) Ntox14 PF15522.6 GAX11005.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Novel toxin 14 RrnaAD PF00398.20 GAX11006.1 - 1.5e-41 142.2 0.0 2.3e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAX11006.1 - 0.0002 22.0 0.0 0.00044 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX11006.1 - 0.00063 19.3 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX11006.1 - 0.0025 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 GAX11006.1 - 0.0085 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 GAX11006.1 - 0.016 15.9 0.0 0.033 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAX11006.1 - 0.025 15.2 0.0 0.2 12.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TPR_12 PF13424.6 GAX11007.1 - 4.2e-19 68.6 7.7 4e-08 33.4 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 GAX11007.1 - 7e-18 64.7 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 GAX11007.1 - 2.5e-09 36.7 3.2 0.0048 16.7 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX11007.1 - 5.3e-08 32.4 2.5 0.25 11.4 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11007.1 - 3.3e-06 26.9 8.4 0.1 12.9 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX11007.1 - 0.0038 17.0 3.4 1.1 9.1 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX11007.1 - 0.0095 15.7 2.2 0.55 9.9 0.4 2.4 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.17 GAX11007.1 - 0.029 14.5 10.4 36 4.8 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat SMBP PF16785.5 GAX11007.1 - 0.048 13.9 1.7 0.43 10.8 1.8 2.4 2 0 0 2 2 2 0 Small metal-binding protein TPR_16 PF13432.6 GAX11007.1 - 0.27 11.9 1.7 31 5.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Sedlin_N PF04628.13 GAX11009.1 - 3.6e-24 85.4 0.0 4.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAX11009.1 - 3e-08 33.7 0.1 7.4e-08 32.4 0.1 1.6 2 0 0 2 2 2 1 Sybindin-like family DUF272 PF03312.15 GAX11009.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF272) GDP_Man_Dehyd PF16363.5 GAX11011.1 - 1.3e-152 508.0 0.0 1.4e-152 507.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX11011.1 - 7.1e-73 245.0 0.1 9.3e-73 244.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX11011.1 - 0.00021 20.5 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAX11011.1 - 0.00091 18.4 0.0 0.0021 17.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GAX11011.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family Endonuclease_1 PF04231.13 GAX11012.1 - 1.3e-33 116.6 0.0 3.6e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 Endonuclease I CoA_trans PF01144.23 GAX11014.1 - 2.5e-89 298.4 2.4 1.8e-50 171.4 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase WD40 PF00400.32 GAX11015.1 - 9.1e-08 32.7 11.2 0.26 12.2 0.1 7.6 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX11015.1 - 0.00086 19.6 0.0 0.67 10.3 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain E1-E2_ATPase PF00122.20 GAX11017.1 - 4.5e-25 88.2 0.4 1.2e-24 86.8 0.4 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAX11017.1 - 6.5e-12 46.2 0.0 6.8e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX11017.1 - 2e-05 24.2 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAX11017.1 - 8.9e-05 22.5 0.1 0.00048 20.2 0.1 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Glucosamine_iso PF01182.20 GAX11018.1 - 1.3e-33 116.8 0.1 2.4e-33 115.9 0.1 1.4 1 1 1 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Methyltransf_16 PF10294.9 GAX11019.1 - 1.5e-10 41.1 0.0 2e-07 30.9 0.0 2.3 1 1 1 2 2 2 2 Lysine methyltransferase Met_10 PF02475.16 GAX11019.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein AlaDh_PNT_C PF01262.21 GAX11019.1 - 0.021 14.1 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 GAX11019.1 - 0.029 15.1 0.0 0.065 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GAX11019.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Thioredoxin_8 PF13905.6 GAX11020.1 - 3.4e-22 78.6 0.0 7.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Transglut_core PF01841.19 GAX11020.1 - 5.6e-09 36.4 0.6 1.8e-08 34.8 0.1 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Thioredoxin PF00085.20 GAX11020.1 - 8.1e-06 25.8 0.0 9e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Rad4 PF03835.15 GAX11020.1 - 0.00095 18.9 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PAW PF04721.17 GAX11020.1 - 0.0013 18.5 0.3 0.0024 17.7 0.3 1.4 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Thioredoxin_2 PF13098.6 GAX11020.1 - 0.004 17.6 0.0 0.015 15.8 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAX11020.1 - 0.0054 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX11020.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Redoxin PepSY_TM PF03929.16 GAX11020.1 - 0.057 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Zn_Tnp_IS1595 PF12760.7 GAX11020.1 - 0.22 11.5 1.7 0.64 10.0 1.7 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DSBA PF01323.20 GAX11021.1 - 2.7e-15 56.6 0.1 3.1e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 GAX11021.1 - 2.8e-06 27.1 0.1 4.1e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Lung_7-TM_R PF06814.13 GAX11022.1 - 1.1e-07 31.4 3.6 1.1e-07 31.4 3.6 2.1 1 1 0 2 2 2 1 Lung seven transmembrane receptor DUF1772 PF08592.11 GAX11022.1 - 0.027 14.8 0.1 0.027 14.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) PHO4 PF01384.20 GAX11022.1 - 2.7 7.0 6.8 0.25 10.3 0.6 1.9 1 1 1 2 2 2 0 Phosphate transporter family Git3 PF11710.8 GAX11023.1 - 0.021 14.6 4.6 0.037 13.8 0.6 2.4 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Lung_7-TM_R PF06814.13 GAX11023.1 - 0.053 12.8 15.2 0.018 14.3 8.5 2.4 2 1 0 2 2 2 0 Lung seven transmembrane receptor TFR_dimer PF04253.15 GAX11023.1 - 0.071 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain DUF2569 PF10754.9 GAX11023.1 - 0.14 12.6 0.3 0.14 12.6 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2569) His_Phos_1 PF00300.22 GAX11025.1 - 1.2e-19 70.7 0.1 3.9e-19 69.1 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SPARC_Ca_bdg PF10591.9 GAX11025.1 - 0.041 14.2 0.3 0.28 11.5 0.1 2.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region SpoU_methylase PF00588.19 GAX11026.1 - 1.4e-25 90.1 0.0 2.1e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAX11026.1 - 1.6e-09 37.9 0.0 1e-06 28.9 0.0 2.5 2 0 0 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding CDRT4 PF15213.6 GAX11026.1 - 0.067 13.8 0.6 0.14 12.7 0.6 1.5 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Gln-synt_C-ter PF18318.1 GAX11027.1 - 1.2e-25 89.7 0.0 2.2e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 GAX11027.1 - 1.2e-17 63.9 0.0 4.6e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain GSIII_N PF12437.8 GAX11027.1 - 2.4e-15 56.6 0.6 8.4e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Rx_N PF18052.1 GAX11027.1 - 0.051 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Rx N-terminal domain Amino_oxidase PF01593.24 GAX11028.1 - 2.2e-17 63.5 0.0 2.7e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAX11028.1 - 8.4e-10 38.8 2.4 2.1e-08 34.2 2.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX11028.1 - 1.5e-09 37.5 0.4 0.00088 18.6 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX11028.1 - 1.9e-08 33.4 2.8 0.00019 20.3 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 GAX11028.1 - 7.6e-08 32.5 0.2 1.6e-07 31.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAX11028.1 - 1.1e-06 28.7 0.9 0.053 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 GAX11028.1 - 0.00011 21.6 0.2 0.0002 20.7 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAX11028.1 - 0.00033 19.8 0.8 0.0066 15.5 0.3 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 GAX11028.1 - 0.00059 19.3 0.3 0.011 15.1 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX11028.1 - 0.0021 18.6 1.0 0.063 13.9 0.7 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 GAX11028.1 - 0.0057 16.1 0.2 0.16 11.3 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 GAX11028.1 - 0.0059 15.9 0.3 0.59 9.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAX11028.1 - 0.007 15.5 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 GAX11028.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FAD_binding_2 PF00890.24 GAX11028.1 - 0.15 11.1 2.3 0.36 9.8 1.2 2.0 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 GAX11028.1 - 0.17 10.7 0.5 0.29 10.0 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase RCC1 PF00415.18 GAX11029.1 - 1.1e-20 74.0 1.1 3.8e-10 40.2 0.0 4.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX11029.1 - 1.5e-12 46.9 4.3 8.8e-07 28.6 0.8 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAX11030.1 - 1.4e-11 44.8 3.4 0.0063 17.1 0.0 3.6 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX11030.1 - 4.8e-08 32.6 0.2 0.0024 17.6 0.0 3.3 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Gly_transf_sug PF04488.15 GAX11031.1 - 4.2e-09 36.9 0.0 2.5e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX11031.1 - 3.4e-06 26.6 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein PFK PF00365.20 GAX11032.1 - 3.5e-57 193.9 0.3 4.4e-57 193.6 0.3 1.1 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.21 GAX11032.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase DAGK_cat PF00781.24 GAX11032.1 - 0.11 12.1 0.0 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Voltage_CLC PF00654.20 GAX11033.1 - 1e-92 311.1 15.0 1e-92 311.1 15.0 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAX11033.1 - 1.5e-07 31.7 0.0 5.4e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 CBS domain p450 PF00067.22 GAX11034.1 - 6.1e-55 186.8 0.0 7.5e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATP-gua_Ptrans PF00217.19 GAX11036.1 - 2.7e-44 151.2 0.0 4.2e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 GAX11036.1 - 2.6e-20 72.6 0.0 5.7e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain HA PF03457.14 GAX11037.1 - 8.9e-08 32.4 0.0 2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain LRR_8 PF13855.6 GAX11039.1 - 4e-25 87.3 34.4 5.4e-09 35.7 4.0 5.5 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX11039.1 - 5.5e-14 52.1 37.2 0.00019 21.7 1.3 6.2 3 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX11039.1 - 0.44 11.3 32.0 5.3 8.0 0.2 9.7 11 0 0 11 11 11 0 Leucine Rich Repeat TUDOR_5 PF18359.1 GAX11040.1 - 0.04 13.6 0.4 0.56 10.0 0.1 2.6 2 1 0 2 2 2 0 Histone methyltransferase Tudor domain 1 BTB PF00651.31 GAX11041.1 - 3.2e-11 43.4 0.2 1.6e-08 34.8 0.0 3.2 1 1 1 2 2 2 2 BTB/POZ domain DUF1098 PF06497.11 GAX11041.1 - 0.19 12.2 0.0 0.44 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) DUF1279 PF06916.13 GAX11042.1 - 0.17 12.5 0.3 0.3 11.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) zf-ZPR1 PF03367.13 GAX11043.1 - 1.1e-94 314.6 1.1 1.9e-46 157.8 0.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain LRR_4 PF12799.7 GAX11045.1 - 0.00014 22.2 1.9 0.14 12.6 0.0 4.3 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX11045.1 - 0.00052 19.7 0.0 0.48 10.2 0.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX11046.1 - 1.3e-08 35.0 0.7 0.093 13.2 0.0 5.2 5 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX11046.1 - 0.0037 17.0 0.1 0.31 10.8 0.0 2.8 3 0 0 3 3 3 2 Leucine rich repeat 2OG-FeII_Oxy_3 PF13640.6 GAX11047.1 - 1.7e-12 48.1 0.0 7.5e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ENTH PF01417.20 GAX11048.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 ENTH domain Pkinase PF00069.25 GAX11049.1 - 9.7e-16 57.9 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11049.1 - 1.7e-11 43.9 0.0 2.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase HSF_DNA-bind PF00447.17 GAX11050.1 - 4.7e-18 65.6 0.9 8.6e-18 64.8 0.9 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding GPI2 PF06432.11 GAX11051.1 - 5.1e-28 98.3 10.5 5.9e-28 98.1 10.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase MlaE PF02405.16 GAX11051.1 - 0.00081 19.1 0.4 0.028 14.1 0.1 2.4 2 0 0 2 2 2 1 Permease MlaE Lig_chan PF00060.26 GAX11051.1 - 0.85 9.4 5.2 1.9 8.3 0.6 2.3 2 0 0 2 2 2 0 Ligand-gated ion channel DUF202 PF02656.15 GAX11051.1 - 6.4 7.3 8.0 0.43 11.1 0.9 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF5600 PF18150.1 GAX11052.1 - 2.3e-36 124.6 1.5 5e-36 123.5 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 GAX11052.1 - 2.3e-19 69.3 0.0 8e-19 67.5 0.0 2.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 GAX11052.1 - 4.6e-15 56.1 0.0 3.3e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Dynamin family EHD_N PF16880.5 GAX11052.1 - 2.4e-10 40.1 5.6 4.4e-10 39.3 5.6 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 GAX11052.1 - 8e-10 38.8 0.0 2.2e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 GAX11052.1 - 0.00025 20.8 0.7 0.0045 16.8 0.2 2.6 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX11052.1 - 0.0041 16.6 0.4 0.013 15.0 0.4 1.9 1 0 0 1 1 1 1 EF hand Roc PF08477.13 GAX11052.1 - 0.0092 16.2 0.0 0.33 11.2 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 GAX11052.1 - 0.015 14.8 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B EF-hand_7 PF13499.6 GAX11052.1 - 0.015 15.7 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EzrA PF06160.12 GAX11052.1 - 0.05 11.8 0.9 0.15 10.2 0.4 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA GTP_EFTU PF00009.27 GAX11052.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 GAX11052.1 - 0.071 12.4 0.0 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 AIG1 family Mito_carr PF00153.27 GAX11053.1 - 1.7e-18 66.3 6.9 3e-07 30.3 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Sporozoite_P67 PF05642.11 GAX11053.1 - 0.11 10.6 4.2 0.15 10.1 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 GAX11053.1 - 1.4 8.2 5.6 1.9 7.7 5.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAX11053.1 - 3.5 5.7 5.2 4.7 5.3 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family OB_NTP_bind PF07717.16 GAX11054.1 - 6.2e-21 74.6 0.0 1.9e-20 73.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAX11054.1 - 7.1e-20 71.3 0.0 7.1e-20 71.3 0.0 3.9 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAX11054.1 - 1.4e-14 54.4 0.5 4e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX11054.1 - 1.6e-07 31.2 0.0 7.3e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX11054.1 - 1.6e-05 25.2 0.1 8.4e-05 22.9 0.1 2.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX11054.1 - 0.00051 19.8 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX11054.1 - 0.00077 19.8 0.0 0.0028 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX11054.1 - 0.0031 16.6 0.0 0.0072 15.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 GAX11054.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAX11054.1 - 0.4 11.2 0.0 0.4 11.2 0.0 3.1 2 1 1 3 3 3 0 ABC transporter ThiF PF00899.21 GAX11055.1 - 4.2e-46 157.3 0.0 7.9e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 GAX11055.1 - 4.3e-30 105.4 0.0 6.6e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus 2-Hacid_dh_C PF02826.19 GAX11055.1 - 0.0024 17.3 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX11055.1 - 0.0054 16.8 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF169 PF02596.15 GAX11055.1 - 0.094 12.6 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 DUF4406 PF14359.6 GAX11055.1 - 0.13 12.7 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) NPL4 PF05021.15 GAX11056.1 - 1.9e-27 96.4 0.3 6.7e-24 84.8 0.3 3.1 1 1 1 2 2 2 2 NPL4 family UN_NPL4 PF11543.8 GAX11056.1 - 0.011 16.2 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 LtrA PF06772.11 GAX11057.1 - 1.7e-15 57.1 16.4 1.2e-14 54.3 16.3 2.0 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) EF-hand_7 PF13499.6 GAX11058.1 - 3.9e-07 30.4 1.6 8e-07 29.4 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX11058.1 - 8.4e-07 28.8 1.9 6.6e-05 22.7 0.7 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX11058.1 - 0.00028 20.6 0.0 0.95 9.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 GAX11058.1 - 0.0014 18.9 0.5 0.008 16.5 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain PMI_typeI PF01238.21 GAX11058.1 - 0.0023 17.2 0.7 0.0027 17.0 0.7 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I EF-hand_1 PF00036.32 GAX11058.1 - 0.0056 16.1 0.1 0.043 13.4 0.1 2.3 2 0 0 2 2 2 1 EF hand DUF881 PF05949.12 GAX11058.1 - 0.1 12.5 1.6 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) TPR_1 PF00515.28 GAX11059.1 - 1e-31 107.4 6.7 4.8e-07 29.3 0.2 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX11059.1 - 1.6e-28 96.5 12.1 1.2e-06 28.2 0.2 7.6 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAX11059.1 - 8.8e-22 77.5 9.5 4.2e-06 27.3 2.5 5.5 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAX11059.1 - 6.5e-21 73.2 16.1 7.4e-05 23.2 0.3 8.3 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11059.1 - 2.4e-17 61.6 6.9 0.00064 19.7 0.1 7.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAX11059.1 - 9e-17 60.5 5.8 0.00013 21.6 0.1 6.5 4 2 2 6 6 6 4 TPR repeat TPR_7 PF13176.6 GAX11059.1 - 1e-16 59.6 7.5 0.00013 21.7 0.1 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAX11059.1 - 5.7e-14 51.4 13.1 0.016 15.5 0.1 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAX11059.1 - 1.3e-13 51.2 17.6 4.1e-06 27.2 0.3 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAX11059.1 - 7.9e-13 48.4 14.9 3.2e-05 24.0 0.4 5.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX11059.1 - 5e-12 45.9 19.1 0.00025 21.3 1.9 5.8 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAX11059.1 - 2e-09 37.5 7.3 1.4 9.7 0.1 7.3 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX11059.1 - 2.9e-05 24.2 7.2 0.22 11.8 0.1 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 GAX11059.1 - 0.00027 21.2 0.3 0.0056 17.0 0.0 4.4 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAX11059.1 - 0.0037 16.5 14.0 0.032 13.5 0.9 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 GAX11059.1 - 0.0043 17.5 5.5 0.019 15.4 0.0 3.5 3 0 0 3 3 3 1 Bacterial transcriptional activator domain Pep_M12B_propep PF01562.19 GAX11059.1 - 0.0049 17.1 3.2 0.012 15.8 3.2 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide TPR_4 PF07721.14 GAX11059.1 - 0.014 16.0 2.2 29 5.7 0.1 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF4248 PF14053.6 GAX11059.1 - 0.014 15.4 2.7 0.098 12.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) MIT PF04212.18 GAX11059.1 - 0.015 15.4 3.1 1.9 8.6 0.1 4.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 GAX11059.1 - 0.069 13.0 20.8 0.8 9.7 0.6 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat TFIIA PF03153.13 GAX11059.1 - 0.071 13.1 24.8 0.1 12.6 24.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NSF PF02071.20 GAX11059.1 - 0.21 12.4 2.0 45 5.5 0.6 3.5 2 0 0 2 2 2 0 Aromatic-di-Alanine (AdAR) repeat ChAPs PF09295.10 GAX11059.1 - 1.4 7.9 10.9 1.9 7.4 0.1 3.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2000 PF09391.10 GAX11060.1 - 2.4 8.1 7.3 1.6 8.6 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2000) Metallophos PF00149.28 GAX11061.1 - 3.6e-11 43.9 1.6 8.9e-10 39.4 1.6 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX11061.1 - 1.6e-05 25.2 0.0 3.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDC73_C PF05179.14 GAX11061.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal OrfB_IS605 PF01385.19 GAX11061.1 - 0.12 12.6 0.2 15 5.8 0.4 2.5 2 0 0 2 2 2 0 Probable transposase Alanine_zipper PF11839.8 GAX11062.1 - 1.2 9.6 30.9 7.4 7.0 5.3 5.2 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF948 PF06103.11 GAX11062.1 - 8.2 6.8 26.0 6.2 7.2 0.4 5.9 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF4820 PF16091.5 GAX11064.1 - 4.1 6.7 5.7 6.4 6.1 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) THUMP PF02926.17 GAX11065.1 - 3.6e-16 59.6 0.1 6.5e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 THUMP domain Ank_5 PF13857.6 GAX11066.1 - 3e-06 27.4 0.4 2.2e-05 24.7 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX11066.1 - 8.4e-05 23.1 0.1 0.024 15.2 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX11066.1 - 0.0001 22.4 0.0 0.51 11.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX11066.1 - 0.00034 20.9 0.8 0.077 13.5 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GAX11066.1 - 0.0012 19.3 0.2 0.052 14.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) HA PF03457.14 GAX11067.1 - 5.1e-10 39.5 0.5 1.3e-09 38.3 0.5 1.6 1 0 0 1 1 1 1 Helicase associated domain DUF3525 PF12039.8 GAX11067.1 - 0.033 12.9 0.2 0.052 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) PBECR4 PF18813.1 GAX11067.1 - 0.096 12.9 0.1 0.24 11.6 0.1 1.6 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 RrnaAD PF00398.20 GAX11068.1 - 5.6e-23 81.4 0.0 6.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF1016_N PF17761.1 GAX11068.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 DUF1016 N-terminal domain TFIIS_M PF07500.14 GAX11069.1 - 2.1e-21 76.5 1.1 2.1e-21 76.5 1.1 2.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 GAX11069.1 - 2.1e-17 62.7 4.6 2.1e-17 62.7 4.6 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 GAX11069.1 - 4.1e-08 33.1 0.1 1.6e-07 31.2 0.1 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain AAA_32 PF13654.6 GAX11069.1 - 0.0022 16.9 1.4 0.0029 16.5 0.9 1.4 1 1 0 1 1 1 1 AAA domain zf-DNL PF05180.12 GAX11069.1 - 0.033 14.1 0.9 0.033 14.1 0.9 1.9 2 0 0 2 2 2 0 DNL zinc finger RGS12_us1 PF16613.5 GAX11069.1 - 0.041 14.2 0.4 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 Unstructured region of RGS12 Aldedh PF00171.22 GAX11069.1 - 0.17 10.3 2.4 0.24 9.9 2.4 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Sec16 PF12932.7 GAX11071.1 - 0.004 17.7 2.3 0.01 16.4 1.1 2.1 1 1 1 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region PIN_9 PF18477.1 GAX11071.1 - 0.032 14.5 0.2 0.093 13.0 0.2 1.8 1 0 0 1 1 1 0 PIN like domain 2OG-FeII_Oxy_2 PF13532.6 GAX11072.1 - 4.7e-32 111.8 0.3 7.2e-32 111.2 0.3 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0020 PF01170.18 GAX11072.1 - 5.9e-28 97.9 0.0 3.7e-27 95.3 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 GAX11072.1 - 1.9e-10 40.8 0.0 4.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX11072.1 - 1.6e-08 35.1 0.0 4.6e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX11072.1 - 2.5e-07 30.4 0.0 5.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 GAX11072.1 - 9.2e-07 28.4 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 GAX11072.1 - 5.3e-06 27.0 0.0 1.3e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX11072.1 - 0.00014 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family THUMP PF02926.17 GAX11072.1 - 0.00035 20.7 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 THUMP domain N6_N4_Mtase PF01555.18 GAX11072.1 - 0.00039 20.2 2.2 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 1 DNA methylase Methyltransf_15 PF09445.10 GAX11072.1 - 0.0044 16.6 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase CMAS PF02353.20 GAX11072.1 - 0.012 14.9 0.1 0.039 13.2 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase FTO_NTD PF12933.7 GAX11072.1 - 0.013 14.8 1.1 0.021 14.1 1.1 1.3 1 0 0 1 1 1 0 FTO catalytic domain Ribonuc_red_lgC PF02867.15 GAX11074.1 - 5.4e-186 619.2 0.0 6.5e-186 618.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAX11074.1 - 5.5e-21 74.4 0.0 1.5e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAX11074.1 - 1.7e-16 60.6 0.0 4.9e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Ion_trans_2 PF07885.16 GAX11075.1 - 6.8e-26 90.0 26.9 1.7e-13 50.3 13.1 2.2 2 0 0 2 2 2 2 Ion channel EF-hand_5 PF13202.6 GAX11075.1 - 2e-10 39.7 1.2 0.0002 20.7 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 GAX11075.1 - 3.4e-10 38.7 1.4 1.3e-05 24.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX11075.1 - 1.7e-08 33.8 0.3 3.1e-05 23.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain Ion_trans PF00520.31 GAX11075.1 - 4.5e-08 32.6 2.1 3.1e-05 23.3 0.1 2.4 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 GAX11075.1 - 8.6e-07 29.3 4.1 0.00021 21.7 0.1 2.9 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 GAX11075.1 - 3.1e-05 23.7 3.2 0.013 15.3 0.4 2.5 1 1 1 2 2 2 2 EF-hand domain pair Lig_chan PF00060.26 GAX11075.1 - 0.013 15.4 3.7 1.1 9.1 3.4 3.2 2 1 0 2 2 2 0 Ligand-gated ion channel SelP_N PF04592.14 GAX11075.1 - 0.96 8.8 9.9 1.7 8.0 9.9 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2530 PF10745.9 GAX11075.1 - 1.6 9.0 4.9 4.5 7.6 3.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) IRK PF01007.20 GAX11075.1 - 2.5 7.9 11.3 3 7.6 2.3 3.0 3 1 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Sec63 PF02889.16 GAX11076.1 - 6.8e-89 297.4 1.7 1.2e-63 214.7 0.6 3.3 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 GAX11076.1 - 1.5e-48 164.9 0.1 5.7e-26 91.4 0.1 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 GAX11076.1 - 1.4e-20 74.0 0.0 7.7e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX11076.1 - 3.8e-16 59.4 0.0 8.6e-08 32.5 0.0 4.0 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_19 PF13245.6 GAX11076.1 - 1.4e-07 32.0 0.3 0.02 15.2 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX11076.1 - 3.6e-07 30.5 1.5 0.013 15.7 0.6 3.5 2 2 0 2 2 2 2 AAA domain T2SSE PF00437.20 GAX11076.1 - 7.5e-06 25.2 1.0 0.012 14.7 0.0 3.5 2 1 0 3 3 3 1 Type II/IV secretion system protein DUF2075 PF09848.9 GAX11076.1 - 0.00044 19.6 0.0 0.0067 15.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 GAX11076.1 - 0.002 17.6 0.0 2.1 7.8 0.0 2.9 3 0 0 3 3 3 2 PhoH-like protein AAA_7 PF12775.7 GAX11076.1 - 0.0056 16.2 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 GAX11076.1 - 0.011 15.4 0.1 1.4 8.5 0.0 3.2 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 GAX11076.1 - 0.011 15.2 3.1 0.2 11.1 1.4 3.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 GAX11076.1 - 0.015 15.1 3.2 0.064 13.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAX11076.1 - 0.02 15.3 6.6 0.18 12.2 0.6 4.4 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAX11076.1 - 0.02 14.6 0.0 8.9 6.0 0.0 3.0 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 GAX11076.1 - 0.023 14.4 0.0 0.33 10.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 GAX11076.1 - 4.1 7.9 8.7 5.6 7.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAX11076.1 - 9.7 6.5 14.3 5.3 7.4 0.0 4.8 5 1 0 5 5 5 0 AAA ATPase domain AhpC-TSA PF00578.21 GAX11077.1 - 9.3e-27 93.4 0.0 1.2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX11077.1 - 1.2e-15 57.5 0.4 1.5e-15 57.2 0.4 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 GAX11077.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.7 1 1 0 1 1 1 0 SCO1/SenC adh_short_C2 PF13561.6 GAX11078.1 - 3.8e-56 190.2 0.0 4.8e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX11078.1 - 3.8e-44 150.5 0.2 5.1e-44 150.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX11078.1 - 2.9e-10 40.4 0.7 1.4e-09 38.1 0.7 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX11078.1 - 3.6e-07 29.9 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAX11078.1 - 0.00058 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 GAX11078.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 GAX11078.1 - 0.0013 18.7 0.0 0.0032 17.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX11078.1 - 0.0017 17.4 0.4 0.0023 17.0 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 GAX11078.1 - 0.0024 18.1 0.0 0.0042 17.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 GAX11078.1 - 0.0035 17.4 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 GAX11078.1 - 0.0048 16.2 0.2 0.013 14.8 0.1 1.7 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 GAX11078.1 - 0.012 14.7 0.1 0.022 13.8 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain CoA_binding_2 PF13380.6 GAX11078.1 - 0.013 16.0 0.1 0.049 14.1 0.0 1.9 2 1 0 2 2 2 0 CoA binding domain 3HCDH_N PF02737.18 GAX11078.1 - 0.095 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nuc_sug_transp PF04142.15 GAX11079.1 - 2.9e-55 187.6 10.7 3.5e-55 187.4 10.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAX11079.1 - 1e-07 31.5 8.1 1.5e-07 31.0 5.8 2.2 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.20 GAX11079.1 - 0.00042 20.5 22.7 0.0019 18.4 4.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family WBS28 PF15164.6 GAX11079.1 - 0.0071 15.7 0.2 0.013 14.8 0.2 1.5 1 0 0 1 1 1 1 Williams-Beuren syndrome chromosomal region 28 protein homologue HEAT_EZ PF13513.6 GAX11080.1 - 1.8e-08 34.7 20.9 0.0095 16.4 0.2 8.3 8 1 1 9 9 9 4 HEAT-like repeat HEAT PF02985.22 GAX11080.1 - 1.1e-05 25.3 16.0 0.21 12.0 0.4 7.4 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.20 GAX11080.1 - 1.6e-05 23.6 0.9 0.064 11.8 0.0 3.3 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 GAX11080.1 - 2.7e-05 24.5 9.6 0.39 11.1 0.3 6.1 4 1 1 5 5 5 2 HEAT repeats RIX1 PF08167.12 GAX11080.1 - 0.011 15.5 0.4 1.8 8.3 0.1 3.1 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 GAX11080.1 - 0.12 12.4 0.1 12 5.9 0.0 3.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Importin_rep_4 PF18808.1 GAX11080.1 - 2.3 8.6 8.4 31 4.9 4.8 3.6 3 0 0 3 3 3 0 Importin repeat NOA36 PF06524.12 GAX11080.1 - 2.4 7.4 9.8 4 6.7 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 GAX11080.1 - 4.4 7.8 8.7 8 6.9 8.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 GAX11080.1 - 8.6 6.4 5.2 1.5 8.9 1.3 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Bestrophin PF01062.21 GAX11082.1 - 1.3e-45 156.1 0.4 1.7e-45 155.7 0.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel hGDE_N PF14699.6 GAX11082.1 - 0.025 14.7 0.1 0.063 13.4 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme SAC3_GANP PF03399.16 GAX11083.1 - 1.4e-21 77.2 4.5 3.8e-20 72.4 4.5 2.2 1 1 0 1 1 1 1 SAC3/GANP family FATC PF02260.20 GAX11083.1 - 0.01 15.7 0.6 0.024 14.4 0.3 1.8 2 0 0 2 2 2 0 FATC domain DUF1635 PF07795.11 GAX11083.1 - 0.037 13.9 0.5 0.073 12.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DLH PF01738.18 GAX11084.1 - 1e-19 71.0 0.0 1.4e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX11084.1 - 0.0075 15.8 0.0 0.68 9.4 0.0 2.5 1 1 1 2 2 2 2 Prolyl oligopeptidase family His_Phos_1 PF00300.22 GAX11085.1 - 5.7e-06 26.1 0.0 1.4e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ATP-synt PF00231.19 GAX11086.1 - 3.3e-88 296.0 0.1 3.9e-88 295.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase DUF5557 PF17712.1 GAX11086.1 - 0.051 13.5 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5557) TP_methylase PF00590.20 GAX11087.1 - 1.1e-36 126.8 0.0 1.4e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1858 PF08984.11 GAX11087.1 - 0.038 14.2 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) AIF_C PF14721.6 GAX11088.1 - 0.21 11.9 0.9 0.96 9.8 0.0 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RPN2_C PF18004.1 GAX11088.1 - 0.9 9.4 7.1 0.11 12.4 0.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Cyclin_N PF00134.23 GAX11089.1 - 1.8e-44 150.6 0.4 1.7e-40 137.7 0.3 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX11089.1 - 3.7e-17 62.5 0.0 7.9e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Gag_p19 PF02228.16 GAX11089.1 - 0.14 12.6 0.0 0.5 10.8 0.0 1.9 2 0 0 2 2 2 0 Major core protein p19 DnaJ PF00226.31 GAX11090.1 - 5.5e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 GAX11090.1 - 0.0078 16.2 0.0 0.0078 16.2 0.0 2.3 2 0 0 2 2 2 1 Pam16 DUF4539 PF15072.6 GAX11091.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) DUF5126 PF17166.4 GAX11092.1 - 0.13 12.1 0.3 0.98 9.3 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5126) DUF3437 PF11919.8 GAX11093.1 - 0.086 12.8 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Spc7 PF08317.11 GAX11094.1 - 0.00022 20.2 17.1 0.00028 19.9 16.0 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein DivIC PF04977.15 GAX11094.1 - 0.21 11.4 24.9 0.18 11.6 5.6 3.8 3 1 1 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 GAX11094.1 - 0.71 9.9 28.9 0.019 15.0 19.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TFR_dimer PF04253.15 GAX11094.1 - 1.2 9.3 5.7 4.1 7.5 0.7 2.5 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Exonuc_VII_L PF02601.15 GAX11094.1 - 1.3 8.5 9.5 2.3 7.7 9.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S46 PF10459.9 GAX11094.1 - 2 6.9 11.6 2.8 6.5 11.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Arfaptin PF06456.13 GAX11094.1 - 4 7.0 15.4 4.1 6.9 0.5 2.5 1 1 2 3 3 3 0 Arfaptin-like domain BLOC1_2 PF10046.9 GAX11094.1 - 8.7 6.7 18.6 12 6.3 11.0 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAGA_bind PF06217.12 GAX11096.1 - 6.7 6.9 12.5 11 6.2 7.1 2.6 2 0 0 2 2 2 0 GAGA binding protein-like family SnoaL_3 PF13474.6 GAX11097.1 - 3e-18 66.2 2.2 3.6e-18 66.0 0.7 1.9 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 GAX11097.1 - 1.7e-07 31.6 0.5 3.6e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) UVR PF02151.19 GAX11097.1 - 1.3e-05 24.7 3.6 3.8e-05 23.3 3.6 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif SnoaL_4 PF13577.6 GAX11097.1 - 0.0059 16.7 0.1 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 GAX11097.1 - 0.006 17.2 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain RapH_N PF18801.1 GAX11097.1 - 0.055 13.6 0.9 0.15 12.2 0.9 1.8 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal Ribosomal_60s PF00428.19 GAX11097.1 - 0.15 12.7 0.3 0.15 12.7 0.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ArgJ PF01960.18 GAX11098.1 - 2.7e-103 345.6 0.0 3.3e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Thioredoxin PF00085.20 GAX11099.1 - 5.2e-20 71.4 0.0 6.6e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX11099.1 - 4.2e-05 24.0 0.1 0.00012 22.5 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAX11099.1 - 0.00018 21.3 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 GAX11099.1 - 0.0017 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAX11099.1 - 0.0045 16.9 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.11 GAX11099.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 GAX11099.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.6 GAX11099.1 - 0.055 13.6 0.1 1.6 8.8 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 GAX11099.1 - 0.094 12.9 0.2 1.5 9.1 0.2 2.4 2 1 0 2 2 2 0 Glutaredoxin DUF713 PF05218.14 GAX11099.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) TerC PF03741.16 GAX11100.1 - 2.5e-33 115.3 1.1 4.4e-33 114.5 1.1 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family RIO1 PF01163.22 GAX11101.1 - 2.1e-50 171.0 0.0 1e-37 129.6 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 GAX11101.1 - 9.1e-05 21.4 0.1 9.1e-05 21.4 0.1 1.8 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAX11101.1 - 0.02 14.8 0.8 0.29 11.0 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 GAX11102.1 - 2e-11 44.0 11.6 4.5e-11 42.9 11.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX11102.1 - 4.5e-07 29.5 3.3 1.2e-06 28.2 3.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX11102.1 - 5.1e-07 29.4 9.3 1.5e-06 28.0 9.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX11102.1 - 3.1e-05 24.1 14.7 0.00013 22.2 14.0 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX11102.1 - 0.00067 19.5 9.8 0.00067 19.5 9.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX11102.1 - 0.0011 19.1 7.1 0.0011 19.1 7.1 2.1 2 1 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 GAX11102.1 - 0.012 15.6 5.9 0.022 14.8 5.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX11102.1 - 0.059 13.4 9.7 0.18 11.9 9.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.6 GAX11102.1 - 0.12 12.5 3.7 0.14 12.4 1.6 2.1 2 1 0 2 2 2 0 PHD-zinc-finger like domain Peptidase_S26 PF10502.9 GAX11102.1 - 0.16 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 zf-C3HC4_3 PF13920.6 GAX11102.1 - 0.18 11.7 10.0 0.12 12.3 6.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mst1_SARAH PF11629.8 GAX11102.1 - 0.2 11.8 0.3 0.43 10.7 0.3 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 RINGv PF12906.7 GAX11102.1 - 0.23 11.6 9.9 0.46 10.7 9.9 1.5 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 GAX11102.1 - 0.26 11.1 4.1 0.68 9.8 4.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 GAX11102.1 - 0.43 10.7 4.7 0.84 9.8 3.5 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 KH_6 PF15985.5 GAX11103.1 - 3.9e-12 46.3 0.0 7.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 GAX11103.1 - 0.05 13.5 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain UNC-50 PF05216.13 GAX11104.1 - 4.4e-71 239.0 16.7 5e-71 238.8 16.7 1.0 1 0 0 1 1 1 1 UNC-50 family Phage_holin_3_6 PF07332.11 GAX11104.1 - 0.012 15.6 3.1 0.012 15.6 3.1 2.6 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III CrgA PF06781.12 GAX11104.1 - 0.051 13.6 0.2 0.051 13.6 0.2 1.9 2 0 0 2 2 2 0 Cell division protein CrgA Sulfate_transp PF00916.20 GAX11106.1 - 1.1e-22 80.4 17.1 1.7e-22 79.7 17.1 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 GAX11106.1 - 1.7e-07 31.2 0.0 2e-06 27.8 0.0 2.7 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain STAS PF01740.21 GAX11106.1 - 0.0029 17.2 0.0 0.0072 15.9 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAX11106.1 - 6.5 7.2 16.5 4.5 7.7 4.0 3.2 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily AAA PF00004.29 GAX11107.1 - 7.9e-53 178.4 0.1 6.5e-38 130.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX11107.1 - 1e-08 35.7 0.0 0.00066 20.1 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 GAX11107.1 - 1.8e-08 34.0 0.0 4.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 GAX11107.1 - 5.6e-08 32.4 0.2 0.00099 18.4 0.1 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 GAX11107.1 - 2.9e-07 30.8 1.1 0.017 15.4 0.4 3.8 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.14 GAX11107.1 - 4.6e-07 30.1 3.2 0.0016 18.6 0.1 3.9 4 0 0 4 4 4 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAX11107.1 - 9.8e-06 25.4 0.2 0.022 14.5 0.0 3.2 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX11107.1 - 1.8e-05 24.8 0.1 0.0013 18.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 GAX11107.1 - 2.3e-05 23.6 0.0 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 GAX11107.1 - 5.2e-05 23.6 0.0 0.03 14.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 GAX11107.1 - 5.5e-05 22.6 1.1 0.013 14.9 0.0 3.3 3 1 1 4 4 4 1 KaiC AAA_14 PF13173.6 GAX11107.1 - 0.00024 21.1 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 GAX11107.1 - 0.00027 20.7 0.3 0.66 9.7 0.0 2.7 3 0 0 3 3 3 2 Sigma-54 interaction domain TniB PF05621.11 GAX11107.1 - 0.00032 20.2 0.2 1.1 8.7 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 GAX11107.1 - 0.00049 19.7 0.1 0.1 12.1 0.0 2.9 2 1 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAX11107.1 - 0.00083 18.8 0.1 0.012 15.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 GAX11107.1 - 0.001 18.3 0.1 0.28 10.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain CDC48_N PF02359.18 GAX11107.1 - 0.0012 18.9 0.0 0.041 14.1 0.0 3.3 2 1 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain TsaE PF02367.17 GAX11107.1 - 0.0016 18.4 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GAX11107.1 - 0.0022 17.7 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 GAX11107.1 - 0.0038 17.2 0.7 0.42 10.5 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.6 GAX11107.1 - 0.0045 16.6 0.3 1.8 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX11107.1 - 0.0052 16.9 0.0 0.45 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX11107.1 - 0.0054 16.5 0.0 0.25 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX11107.1 - 0.0066 17.0 0.0 0.35 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GAX11107.1 - 0.0088 15.5 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein CDC48_2 PF02933.17 GAX11107.1 - 0.0094 15.7 0.3 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ATPase_2 PF01637.18 GAX11107.1 - 0.01 15.7 0.1 0.36 10.7 0.0 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 GAX11107.1 - 0.012 16.0 0.2 0.74 10.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAX11107.1 - 0.019 14.2 0.0 5.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_3 PF07726.11 GAX11107.1 - 0.028 14.3 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAX11107.1 - 0.028 14.3 0.0 0.27 11.1 0.0 2.5 3 0 0 3 3 2 0 Rad17 P-loop domain IPT PF01745.16 GAX11107.1 - 0.11 11.8 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.9 GAX11107.1 - 0.15 11.3 0.0 3.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 GAX11107.1 - 0.16 12.2 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Tugs PF17840.1 GAX11107.1 - 0.17 12.1 0.0 0.72 10.1 0.0 2.2 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain AAA_19 PF13245.6 GAX11107.1 - 2.3 8.5 4.5 2.6 8.3 0.0 3.1 4 1 0 4 4 2 0 AAA domain GH115_C PF17829.1 GAX11108.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain MbeB_N PF04837.12 GAX11108.1 - 1.6 9.1 7.0 1.9 8.8 0.9 2.8 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DEAD PF00270.29 GAX11109.1 - 4.9e-49 166.5 0.1 1.6e-48 164.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX11109.1 - 2.7e-24 85.6 0.0 4.5e-23 81.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAX11109.1 - 1.1e-16 60.8 0.1 2.2e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAX11109.1 - 3.2e-07 30.5 0.2 1.4e-06 28.4 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAX11109.1 - 0.00058 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SecA_DEAD PF07517.14 GAX11109.1 - 0.0016 17.8 0.1 0.0033 16.7 0.1 1.6 2 0 0 2 2 2 1 SecA DEAD-like domain ERCC3_RAD25_C PF16203.5 GAX11109.1 - 0.008 15.4 0.0 0.008 15.4 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 GAX11109.1 - 0.032 13.9 0.1 0.47 10.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AMP-binding PF00501.28 GAX11110.1 - 1.2e-07 30.7 0.0 1.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme S_4TM PF18159.1 GAX11110.1 - 0.13 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Acetyltransf_1 PF00583.25 GAX11111.1 - 7.1e-14 52.0 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX11111.1 - 2.9e-12 46.6 0.0 4.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX11111.1 - 4.4e-11 43.1 0.0 6.7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX11111.1 - 1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAX11111.1 - 2e-05 25.3 0.3 0.00018 22.2 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX11111.1 - 0.0064 16.6 0.1 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAX11111.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 GAX11111.1 - 0.011 15.7 0.1 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PanZ PF12568.8 GAX11111.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 GAX11111.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase UCR_14kD PF02271.16 GAX11112.1 - 2.5e-12 46.6 0.1 2.7e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit EMP70 PF02990.16 GAX11113.1 - 1.9e-172 574.5 2.4 1.9e-172 574.5 2.4 2.2 2 1 0 2 2 2 1 Endomembrane protein 70 WD40 PF00400.32 GAX11114.1 - 2.3e-18 66.2 7.7 7.9e-07 29.7 0.5 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat TrmO PF01980.16 GAX11115.1 - 8.7e-36 122.7 0.0 2.1e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 GAX11115.1 - 1e-05 25.6 0.1 5.2e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 TrmO C-terminal domain TPR_12 PF13424.6 GAX11116.1 - 2.1e-06 27.9 11.2 0.0018 18.5 0.2 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX11116.1 - 0.00048 20.0 3.0 0.29 11.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX11116.1 - 0.034 14.0 8.1 1.7 8.6 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX11116.1 - 0.97 9.2 6.8 13 5.5 0.1 3.9 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 GAX11116.1 - 4.8 7.4 9.7 0.46 10.6 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SelR PF01641.18 GAX11117.1 - 3.8e-37 127.1 0.0 5e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 SelR domain HypA PF01155.19 GAX11117.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Mss51 PF13824.6 GAX11117.1 - 0.23 11.6 0.6 8.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 MINDY_DUB PF04424.13 GAX11118.1 - 2.9e-24 85.3 0.1 1e-23 83.6 0.0 2.0 2 0 0 2 2 2 1 MINDY deubiquitinase UIM PF02809.20 GAX11118.1 - 8.6 6.5 10.4 0.21 11.6 0.4 3.4 3 0 0 3 3 3 0 Ubiquitin interaction motif ECH_2 PF16113.5 GAX11119.1 - 2.6e-106 355.9 0.0 3.2e-84 283.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAX11119.1 - 7.6e-24 84.4 0.0 3.3e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase YitT_membrane PF02588.15 GAX11119.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 ECH_2 PF16113.5 GAX11120.1 - 1.7e-97 326.9 0.0 2.3e-95 319.9 0.0 2.4 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAX11120.1 - 2.1e-22 79.7 0.0 4.8e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Fasciclin PF02469.22 GAX11121.1 - 2.4e-89 296.1 0.1 1e-22 80.7 0.0 4.2 4 0 0 4 4 4 4 Fasciclin domain DUF4397 PF14344.6 GAX11121.1 - 0.06 14.1 0.0 28 5.5 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4397) partial_CstF PF15861.5 GAX11121.1 - 0.17 11.7 7.7 17 5.3 0.0 5.0 4 1 1 5 5 5 0 Partial cleavage stimulation factor domain zf-C2H2_aberr PF17017.5 GAX11121.1 - 2.9 8.0 4.0 2e+02 2.0 0.0 3.8 4 0 0 4 4 4 0 Aberrant zinc-finger AMP-binding PF00501.28 GAX11122.1 - 2e-48 165.1 0.0 2.4e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAX11122.1 - 3.9e-15 56.6 0.0 8.4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Diphthami_syn_2 PF01902.17 GAX11123.1 - 1.7e-25 89.8 0.0 3.4e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 GAX11123.1 - 1.7e-20 73.2 0.1 1.1e-09 38.3 0.0 3.4 3 0 0 3 3 3 2 Endoribonuclease L-PSP YGGT PF02325.17 GAX11123.1 - 1e-17 64.3 4.6 2.2e-17 63.2 4.6 1.6 1 0 0 1 1 1 1 YGGT family CH_2 PF06294.11 GAX11123.1 - 0.1 12.7 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 CH-like domain in sperm protein Glyco_transf_10 PF00852.19 GAX11124.1 - 6.4e-21 74.9 0.6 1.3e-20 73.9 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Endopep_inhib PF16800.5 GAX11124.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor EMP24_GP25L PF01105.24 GAX11128.1 - 9.3e-24 84.4 1.1 2.6e-23 82.9 1.1 1.8 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_M18 PF02127.15 GAX11130.1 - 8.8e-141 469.6 0.0 1e-140 469.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAX11130.1 - 6.2e-06 25.4 0.1 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase SRP54 PF00448.22 GAX11131.1 - 4.6e-05 23.1 0.1 8.6e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 GAX11131.1 - 7.5e-05 22.5 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX11131.1 - 0.00016 22.1 0.2 0.0011 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 GAX11131.1 - 0.0024 17.8 0.3 0.006 16.5 0.3 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Rad17 PF03215.15 GAX11131.1 - 0.0031 17.4 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 GAX11131.1 - 0.007 16.6 0.2 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 GAX11131.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_17 PF13207.6 GAX11131.1 - 0.031 14.7 0.2 0.088 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain MobB PF03205.14 GAX11131.1 - 0.066 13.1 0.3 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Torsin PF06309.11 GAX11131.1 - 0.067 13.3 0.2 0.18 11.9 0.1 1.7 2 0 0 2 2 2 0 Torsin AAA_33 PF13671.6 GAX11131.1 - 0.067 13.4 2.6 0.092 12.9 1.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX11131.1 - 0.07 13.7 0.0 0.21 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 GAX11131.1 - 0.076 12.0 0.1 0.15 11.0 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 GAX11131.1 - 0.079 12.2 0.1 0.85 8.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TetR_C_21 PF17926.1 GAX11131.1 - 0.11 12.7 5.1 8.3 6.6 0.1 3.3 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain PPK2 PF03976.14 GAX11131.1 - 0.11 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Thymidylate_kin PF02223.17 GAX11131.1 - 0.14 11.8 0.4 0.34 10.6 0.1 1.8 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 GAX11131.1 - 0.26 11.2 1.0 0.42 10.5 0.3 1.7 2 0 0 2 2 2 0 NTPase Ploopntkinase2 PF18747.1 GAX11131.1 - 0.27 10.5 1.3 0.54 9.5 0.4 2.0 2 1 0 2 2 2 0 P-loop Nucleotide Kinase2 Flg_hook PF02120.16 GAX11131.1 - 0.28 11.1 3.5 6.7 6.7 0.2 2.7 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK DNA_pol_A_exoN PF18305.1 GAX11132.1 - 0.062 13.6 1.8 0.15 12.3 0.3 2.5 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain Motilin_ghrelin PF04644.12 GAX11132.1 - 0.27 11.1 5.6 0.84 9.5 2.0 2.4 2 0 0 2 2 2 0 Motilin/ghrelin DUF4047 PF13256.6 GAX11132.1 - 0.67 10.2 3.9 1.6 9.0 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) CoaE PF01121.20 GAX11135.1 - 1.9e-36 125.4 0.0 2.3e-30 105.6 0.0 2.6 3 0 0 3 3 3 2 Dephospho-CoA kinase AAA_18 PF13238.6 GAX11135.1 - 0.0043 17.6 0.1 1.2 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain RRP14 PF15459.6 GAX11136.1 - 0.0022 18.5 2.4 0.0022 18.5 2.4 2.1 2 0 0 2 2 2 1 60S ribosome biogenesis protein Rrp14 DnaJ PF00226.31 GAX11137.1 - 3.1e-10 40.0 0.0 8.4e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 GAX11137.1 - 0.098 12.5 0.0 0.77 9.6 0.0 2.6 1 0 0 1 1 1 0 GYF domain 2 COPI_C PF06957.11 GAX11137.1 - 0.23 10.2 2.9 0.24 10.1 1.4 1.7 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus FPN1 PF06963.12 GAX11139.1 - 8.5e-91 304.7 10.4 1.5e-90 303.8 10.4 1.4 1 1 0 1 1 1 1 Ferroportin1 (FPN1) IRK PF01007.20 GAX11139.1 - 0.037 13.9 0.5 0.11 12.4 0.5 1.7 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain His_Phos_1 PF00300.22 GAX11140.1 - 8.2e-12 45.2 0.2 8.2e-07 28.9 0.2 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) NTP_transf_8 PF12281.8 GAX11140.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase Patched PF02460.18 GAX11141.1 - 2.1e-91 307.3 13.7 3.1e-91 306.7 13.7 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 GAX11141.1 - 6.4e-37 126.8 6.5 6.4e-37 126.8 6.5 3.5 3 1 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 GAX11141.1 - 0.024 13.6 26.0 0.075 11.9 11.1 3.1 3 0 0 3 3 3 0 MMPL family DUF2157 PF09925.9 GAX11141.1 - 2.1 8.1 11.7 0.68 9.7 0.4 3.3 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) RRM_1 PF00076.22 GAX11142.1 - 0.0007 19.4 0.0 0.031 14.1 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.16 GAX11143.1 - 5.4e-10 39.7 0.1 1.3e-09 38.5 0.1 1.7 1 1 0 1 1 1 1 Trm112p-like protein EIF_2_alpha PF07541.12 GAX11144.1 - 7.5e-39 132.4 0.0 1.5e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 GAX11144.1 - 6.1e-13 48.9 1.7 1.1e-12 48.1 0.5 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Ssl1 PF04056.14 GAX11145.1 - 6.2e-54 182.8 0.0 8.7e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 GAX11145.1 - 1.3e-16 60.6 15.9 1e-15 57.7 10.3 2.5 2 0 0 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 GAX11145.1 - 8.4e-08 32.8 0.0 2.1e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain IBR PF01485.21 GAX11145.1 - 0.0028 17.8 3.0 0.0028 17.8 3.0 3.3 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain VWA_3 PF13768.6 GAX11145.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain DZR PF12773.7 GAX11145.1 - 0.078 13.0 16.0 0.43 10.6 0.1 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-AN1 PF01428.16 GAX11145.1 - 1.9 8.7 13.7 8.4 6.6 6.9 2.8 2 0 0 2 2 2 0 AN1-like Zinc finger Pkinase PF00069.25 GAX11146.1 - 1e-14 54.6 0.0 1.5e-13 50.8 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain F-box-like PF12937.7 GAX11146.1 - 0.00045 20.1 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Pkinase_Tyr PF07714.17 GAX11146.1 - 0.00056 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Nop14 PF04147.12 GAX11147.1 - 0.0029 15.9 29.2 0.0029 15.9 29.2 2.2 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 GAX11147.1 - 0.0043 16.5 26.8 0.0043 16.5 26.8 2.2 2 0 0 2 2 2 1 SDA1 Amino_oxidase PF01593.24 GAX11148.1 - 4.9e-20 72.3 0.3 9.3e-18 64.7 0.0 2.5 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX11148.1 - 2.7e-10 40.3 0.2 7.2e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX11148.1 - 1e-07 31.9 1.0 8.1e-07 28.9 0.9 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX11148.1 - 2.6e-07 30.1 4.6 3.2e-05 23.2 0.2 2.6 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 GAX11148.1 - 7.6e-06 25.4 0.3 0.0012 18.2 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX11148.1 - 1.9e-05 24.0 0.3 5.4e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GAX11148.1 - 8e-05 22.0 0.1 0.00055 19.3 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAX11148.1 - 0.00031 20.2 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX11148.1 - 0.0011 17.8 1.1 0.014 14.2 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 GAX11148.1 - 0.0013 17.9 0.5 0.012 14.7 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 GAX11148.1 - 0.0014 17.8 0.4 0.011 14.9 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GAX11148.1 - 0.0022 18.5 0.0 0.086 13.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 GAX11148.1 - 0.014 14.0 0.1 0.89 8.0 0.1 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 GAX11148.1 - 0.039 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase eIF2A PF08662.11 GAX11149.1 - 1.7e-39 135.7 0.2 1.5e-36 126.1 0.1 3.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 GAX11149.1 - 1.4e-07 31.2 0.4 1.8e-06 27.7 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 GAX11149.1 - 0.0034 17.6 0.0 12 6.3 0.0 4.7 5 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 GAX11149.1 - 0.0064 15.6 0.0 0.024 13.7 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region Metal_resist PF13801.6 GAX11149.1 - 0.0073 16.5 4.9 0.015 15.4 4.9 1.4 1 0 0 1 1 1 1 Heavy-metal resistance DUF1623 PF07785.11 GAX11149.1 - 0.051 13.7 0.0 1.3 9.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1623) FlgN PF05130.12 GAX11149.1 - 0.42 11.1 3.0 0.81 10.2 3.0 1.4 1 0 0 1 1 1 0 FlgN protein Rer1 PF03248.13 GAX11150.1 - 9.3e-65 217.5 6.6 1.1e-64 217.3 6.6 1.0 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.6 GAX11150.1 - 5.9 6.5 6.4 20 4.8 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Proteasome PF00227.26 GAX11151.1 - 1.1e-37 129.4 0.1 1.4e-37 129.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit APH PF01636.23 GAX11152.1 - 2.1e-37 129.3 0.4 3.2e-37 128.7 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAX11152.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 GAX11152.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_1d PF00750.19 GAX11153.1 - 2.8e-113 378.4 0.0 4.5e-113 377.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAX11153.1 - 9e-22 77.5 0.4 1.9e-21 76.4 0.4 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAX11153.1 - 2e-10 41.1 0.0 7.3e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain GST_C_3 PF14497.6 GAX11153.1 - 0.14 12.4 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Beta-lactamase2 PF13354.6 GAX11153.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase enzyme family SOUL PF04832.12 GAX11155.1 - 7.8e-36 123.8 0.7 1.3e-35 123.0 0.7 1.4 1 0 0 1 1 1 1 SOUL heme-binding protein PDZ PF00595.24 GAX11156.1 - 6e-06 26.5 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX11156.1 - 6.8e-06 25.8 0.0 2.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX11156.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 PDZ domain RVT_connect PF06815.13 GAX11156.1 - 0.27 11.5 1.1 0.63 10.3 1.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase connection domain RVT_2 PF07727.14 GAX11157.1 - 9.4e-08 32.0 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX11157.1 - 3.4e-07 30.5 0.0 1.1e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Aminotran_5 PF00266.19 GAX11158.1 - 6.4e-146 486.1 0.0 7.4e-146 485.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAX11158.1 - 2.4e-06 27.1 0.4 6.4e-05 22.4 0.6 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAX11158.1 - 5.8e-06 25.1 0.1 8.6e-06 24.5 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 GAX11158.1 - 0.00063 18.4 0.0 0.0011 17.6 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase MORN PF02493.20 GAX11159.1 - 1.1e-43 144.6 41.0 2.3e-07 30.3 0.5 9.5 9 0 0 9 9 9 9 MORN repeat Zip PF02535.22 GAX11159.1 - 7.6 5.7 5.0 15 4.6 5.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter GcpE PF04551.14 GAX11160.1 - 3.6e-150 499.9 0.0 5.1e-150 499.4 0.0 1.2 1 0 0 1 1 1 1 GcpE protein Sgf11 PF08209.11 GAX11160.1 - 0.7 9.5 3.3 1 9.0 0.1 2.5 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) CAC1F_C PF16885.5 GAX11161.1 - 0.0081 15.9 3.7 0.01 15.6 3.7 1.1 1 0 0 1 1 1 1 Voltage-gated calcium channel subunit alpha, C-term CENP-B_dimeris PF09026.10 GAX11161.1 - 0.023 15.1 2.6 0.31 11.4 2.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2052 PF09747.9 GAX11161.1 - 0.25 11.4 7.1 0.03 14.5 3.0 1.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Pox_RNA_Pol_19 PF05320.12 GAX11161.1 - 0.41 10.6 4.7 0.68 9.9 4.7 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YL1 PF05764.13 GAX11161.1 - 1.1 9.3 17.2 2.2 8.4 17.2 1.5 1 1 0 1 1 1 0 YL1 nuclear protein Microtub_bind PF13931.6 GAX11161.1 - 1.8 9.0 9.8 0.13 12.7 5.0 1.4 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding DDHD PF02862.17 GAX11161.1 - 1.8 8.6 5.9 0.55 10.4 3.1 1.5 1 1 1 2 2 2 0 DDHD domain Ribosomal_L27e PF01777.18 GAX11161.1 - 5.2 7.5 11.3 3.4 8.1 5.7 2.5 2 1 0 2 2 2 0 Ribosomal L27e protein family Paf67 PF10255.9 GAX11162.1 - 8.9e-83 278.5 0.0 3.8e-82 276.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 ATG22 PF11700.8 GAX11164.1 - 2.3e-22 79.3 20.2 1.6e-11 43.6 15.1 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAX11164.1 - 7.1e-12 44.9 27.4 7.1e-12 44.9 27.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily SPRY PF00622.28 GAX11166.1 - 2.8e-27 95.2 0.9 4.4e-27 94.6 0.1 1.8 2 0 0 2 2 2 1 SPRY domain Telomere_Sde2_2 PF13297.6 GAX11166.1 - 2.5e-25 87.9 0.4 4.5e-25 87.1 0.4 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 GAX11166.1 - 3.1e-15 56.4 10.5 1.8e-14 53.9 10.5 2.1 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Parvo_coat PF00740.18 GAX11166.1 - 0.037 12.7 0.1 0.055 12.1 0.1 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Neuralized PF07177.12 GAX11166.1 - 0.092 12.8 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 Neuralized Moulting_cycle PF04870.16 GAX11166.1 - 5.3 6.2 10.6 1.1 8.5 5.7 1.9 2 0 0 2 2 2 0 Moulting cycle TLD PF07534.16 GAX11167.1 - 4.2e-27 95.1 0.0 6.9e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 TLD Laminin_G_3 PF13385.6 GAX11169.1 - 7e-06 26.3 0.2 2.1e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Cadherin_3 PF16184.5 GAX11169.1 - 7.3e-05 22.7 0.1 0.015 15.3 0.0 3.4 3 0 0 3 3 3 1 Cadherin-like WW PF00397.26 GAX11169.1 - 0.00042 20.3 0.4 0.0013 18.8 0.4 1.8 1 0 0 1 1 1 1 WW domain Big_9 PF17963.1 GAX11169.1 - 0.0046 17.7 0.0 0.059 14.1 0.0 2.7 1 1 0 1 1 1 1 Bacterial Ig domain Cadherin_4 PF17803.1 GAX11169.1 - 0.033 14.8 0.0 0.12 13.0 0.0 2.0 1 0 0 1 1 1 0 Bacterial cadherin-like domain 2OG-FeII_Oxy_3 PF13640.6 GAX11170.1 - 6.3e-09 36.6 0.0 1.3e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5357 PF17310.2 GAX11170.1 - 0.11 11.1 0.2 0.16 10.5 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Pkinase PF00069.25 GAX11171.1 - 1.6e-51 175.2 0.6 3.1e-51 174.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11171.1 - 1.4e-33 116.3 0.0 2.9e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 GAX11171.1 - 0.011 15.9 0.1 0.03 14.5 0.1 1.7 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain Sds3 PF08598.11 GAX11171.1 - 0.098 12.6 14.4 0.099 12.6 12.8 1.8 2 0 0 2 2 2 0 Sds3-like FapA PF03961.13 GAX11171.1 - 7.3 5.1 7.5 12 4.3 7.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tim17 PF02466.19 GAX11172.1 - 0.0031 17.9 0.1 0.0046 17.3 0.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Voltage_CLC PF00654.20 GAX11173.1 - 3.9e-65 220.4 32.2 2.9e-64 217.6 26.6 2.1 1 1 0 2 2 2 2 Voltage gated chloride channel HECT PF00632.25 GAX11174.1 - 3e-77 260.1 0.0 4.6e-77 259.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 GAX11174.1 - 2.7e-29 100.3 36.0 5.1e-08 32.5 0.5 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAX11174.1 - 2.6e-28 98.4 22.9 4.5e-09 36.8 0.2 8.2 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Pentapeptide PF00805.22 GAX11175.1 - 4.7e-15 54.9 6.1 5.3e-09 35.5 1.7 3.5 2 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GAX11175.1 - 1.4e-10 41.2 0.3 2.2e-09 37.3 0.1 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 GAX11175.1 - 5.4e-09 36.1 4.7 4e-08 33.3 0.3 2.8 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Ank_3 PF13606.6 GAX11175.1 - 0.072 13.7 3.7 6.2 7.7 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat DNA_pol_phi PF04931.13 GAX11176.1 - 0.11 10.5 12.5 0.2 9.7 12.3 1.5 2 0 0 2 2 2 0 DNA polymerase phi Tom37 PF10568.9 GAX11177.1 - 4.5e-08 33.4 0.9 0.0022 18.3 0.0 3.4 3 0 0 3 3 3 2 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 GAX11177.1 - 0.0031 17.7 0.1 0.008 16.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAX11177.1 - 0.02 14.6 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Peptidase_C69 PF03577.15 GAX11178.1 - 1.6e-49 168.9 7.5 1.2e-43 149.5 5.2 2.9 1 1 1 2 2 2 2 Peptidase family C69 Bestrophin PF01062.21 GAX11179.1 - 2.3e-16 60.1 2.2 3.5e-16 59.5 2.2 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel cNMP_binding PF00027.29 GAX11179.1 - 6.8e-12 45.3 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MnmE_helical PF12631.7 GAX11181.1 - 4.7e-47 160.8 0.5 6.2e-47 160.4 0.5 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 GAX11181.1 - 8.7e-36 122.7 0.0 2.5e-35 121.3 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 GAX11181.1 - 7.2e-22 77.6 0.1 1.5e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX11181.1 - 1.2e-09 37.8 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX11181.1 - 0.00037 20.6 0.0 0.00062 19.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 GAX11181.1 - 0.012 16.2 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF5569 PF17729.1 GAX11181.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5569) zf-MYND PF01753.18 GAX11182.1 - 0.04 14.0 18.4 0.2 11.8 18.4 2.3 1 1 0 1 1 1 0 MYND finger BcsB PF03170.13 GAX11183.1 - 0.082 11.3 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit zf-C3HC4_3 PF13920.6 GAX11184.1 - 1.6e-11 43.9 6.5 3e-11 43.0 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH3_3 PF08239.11 GAX11184.1 - 0.00078 19.7 0.0 0.73 10.2 0.0 2.8 2 0 0 2 2 2 2 Bacterial SH3 domain zf-RING_2 PF13639.6 GAX11184.1 - 0.054 13.8 7.8 0.13 12.6 7.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-P11 PF03854.14 GAX11184.1 - 0.33 10.7 3.7 0.71 9.6 3.7 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_5 PF14634.6 GAX11184.1 - 2.2 8.3 6.7 5 7.2 6.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAX11184.1 - 8.1 6.4 8.4 20 5.1 8.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M1 PF01433.20 GAX11186.1 - 2.9e-80 268.9 0.2 4.4e-80 268.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAX11186.1 - 8.7e-64 216.0 0.0 8.6e-63 212.8 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAX11186.1 - 6.4e-42 143.8 0.5 1e-41 143.2 0.5 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Taeniidae_ag PF05596.11 GAX11186.1 - 0.05 13.6 0.0 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Taeniidae antigen WLM PF08325.10 GAX11186.1 - 0.17 11.9 0.0 0.96 9.5 0.0 2.0 2 0 0 2 2 2 0 WLM domain DNA_pol_A_exo1 PF01612.20 GAX11187.1 - 5.2e-14 52.3 0.0 1.7e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease Ank_2 PF12796.7 GAX11187.1 - 1.7e-09 38.2 0.0 5.1e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX11187.1 - 1.1e-06 28.8 0.1 0.0033 17.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX11187.1 - 1.9e-06 28.0 0.0 0.14 12.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAX11187.1 - 3.6e-06 27.4 0.0 0.015 15.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX11187.1 - 2.4e-05 24.3 0.0 0.35 11.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat NAP PF00956.18 GAX11187.1 - 0.016 14.4 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Polyketide_cyc PF03364.20 GAX11188.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.8 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Pkinase PF00069.25 GAX11189.1 - 1.3e-20 73.9 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11189.1 - 2.9e-12 46.4 0.0 4.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX11189.1 - 0.023 14.1 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 GAX11189.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 MMR_HSR1_Xtn PF16897.5 GAX11190.1 - 1.1e-34 118.7 0.0 2e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 GAX11190.1 - 2.2e-19 69.6 0.0 5.2e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 GAX11190.1 - 1.6e-17 63.3 0.0 2.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 GAX11190.1 - 4e-09 36.2 0.0 8.6e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX11190.1 - 0.00017 21.7 0.1 0.029 14.4 0.0 2.5 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 GAX11190.1 - 0.004 16.5 0.2 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 AIG1 family SRPRB PF09439.10 GAX11190.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Y1_Tnp PF01797.16 GAX11191.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Transposase IS200 like ATP-grasp_4 PF13535.6 GAX11192.1 - 2e-13 50.2 0.0 3.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAX11192.1 - 8.4e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAX11192.1 - 1.3e-07 31.6 0.0 3e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 GAX11192.1 - 2.4e-06 27.3 0.0 1.2e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 GAX11192.1 - 0.0012 18.3 0.0 0.16 11.4 0.1 2.3 2 0 0 2 2 2 1 ATP-grasp domain LAL_C2 PF18603.1 GAX11192.1 - 0.029 14.5 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 FERM_N_2 PF18038.1 GAX11192.1 - 0.048 14.5 0.4 0.13 13.2 0.4 1.7 1 0 0 1 1 1 0 FERM N-terminal domain Dala_Dala_lig_C PF07478.13 GAX11192.1 - 0.054 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_YheCD PF14398.6 GAX11192.1 - 0.068 12.4 0.2 0.16 11.2 0.2 1.6 1 1 0 1 1 1 0 YheC/D like ATP-grasp GSH-S_ATP PF02955.16 GAX11192.1 - 0.098 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain RimK PF08443.11 GAX11192.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain PALP PF00291.25 GAX11194.1 - 1.1e-33 116.9 0.0 1.3e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 GAX11195.1 - 9.4e-12 45.4 0.0 1.4e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain MMR_HSR1 PF01926.23 GAX11196.1 - 2.7e-11 43.5 0.0 2.2e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX11196.1 - 5.7e-05 22.7 0.0 0.0026 17.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX11196.1 - 0.0016 18.4 0.1 0.36 10.7 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase IBB PF01749.20 GAX11196.1 - 0.0039 17.6 2.8 0.0039 17.6 2.8 2.1 2 0 0 2 2 2 1 Importin beta binding domain CNDH2_C PF16858.5 GAX11196.1 - 0.037 13.9 6.3 0.82 9.5 0.8 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop53 PF07767.11 GAX11196.1 - 0.21 11.0 18.2 0.63 9.4 5.8 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) EBV-NA3 PF05009.12 GAX11196.1 - 1.6 8.2 8.5 0.14 11.6 2.2 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FYDLN_acid PF09538.10 GAX11196.1 - 7.4 7.3 17.1 8.2 7.2 5.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TRAP_alpha PF03896.16 GAX11196.1 - 9 5.4 6.7 0.58 9.3 0.6 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit AAA_22 PF13401.6 GAX11197.1 - 3.7e-05 24.0 0.0 0.00011 22.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAX11197.1 - 0.00014 22.4 0.3 0.72 10.4 0.3 2.4 1 1 1 2 2 2 2 ABC transporter AAA_33 PF13671.6 GAX11197.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 GAX11197.1 - 0.0014 18.1 0.2 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 GAX11197.1 - 0.012 14.8 0.1 0.033 13.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_21 PF13304.6 GAX11197.1 - 0.021 14.7 1.3 2.5 7.8 0.9 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TMEM154 PF15102.6 GAX11197.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family AAA_16 PF13191.6 GAX11197.1 - 0.03 14.7 0.1 0.1 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 GAX11197.1 - 0.036 13.7 0.1 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAX11197.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Phage_holin_T PF11031.8 GAX11197.1 - 0.056 12.9 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage T holin LapA_dom PF06305.11 GAX11197.1 - 0.069 13.0 1.9 0.31 10.9 0.1 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain NACHT PF05729.12 GAX11197.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain G0-G1_switch_2 PF15103.6 GAX11197.1 - 0.07 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 AAA_29 PF13555.6 GAX11197.1 - 0.14 11.9 0.3 0.4 10.4 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Wzy_C PF04932.15 GAX11197.1 - 0.15 11.7 6.5 0.62 9.7 0.0 2.6 2 1 0 2 2 2 0 O-Antigen ligase EphA2_TM PF14575.6 GAX11197.1 - 0.41 11.6 0.0 0.41 11.6 0.0 2.2 3 0 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.8 GAX11197.1 - 1.7 8.8 0.0 1.7 8.8 0.0 2.4 3 1 1 4 4 3 0 Protein of unknown function (DUF2615) Sensor PF13796.6 GAX11197.1 - 3.9 7.5 12.9 0.17 12.0 0.3 2.6 2 1 0 2 2 2 0 Putative sensor ABC2_membrane_2 PF12679.7 GAX11197.1 - 8.4 5.6 12.8 32 3.7 0.0 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein Sel1 PF08238.12 GAX11199.1 - 2.3e-16 59.9 0.1 5.8e-06 26.8 0.0 3.4 3 0 0 3 3 3 3 Sel1 repeat ATP-synt_F PF01990.17 GAX11199.1 - 0.033 14.5 0.0 0.084 13.2 0.0 1.7 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit DUF1350 PF07082.11 GAX11200.1 - 6e-29 101.1 0.0 6.6e-18 64.9 0.0 2.5 1 1 2 3 3 3 2 Protein of unknown function (DUF1350) Abhydrolase_6 PF12697.7 GAX11200.1 - 0.029 15.0 0.2 0.11 13.1 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Methyltransf_19 PF04672.12 GAX11200.1 - 0.055 13.0 0.1 0.088 12.3 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase HSD3 PF15244.6 GAX11200.1 - 0.094 12.2 1.2 0.13 11.7 1.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Gly_transf_sug PF04488.15 GAX11202.1 - 3.1e-09 37.4 0.0 6.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX11202.1 - 0.0037 16.7 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 GAX11202.1 - 0.0073 15.6 0.1 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain bZIP_2 PF07716.15 GAX11203.1 - 1e-11 44.7 23.4 8.2e-06 25.8 11.1 2.4 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 GAX11203.1 - 9.2e-10 38.5 23.9 1.2e-06 28.5 11.7 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 GAX11203.1 - 0.0011 19.5 20.1 0.0019 18.7 1.6 2.7 2 1 0 2 2 2 1 bZIP Maf transcription factor CCDC106 PF15794.5 GAX11203.1 - 0.036 13.8 19.3 0.11 12.2 5.4 3.2 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 106 Auxin_inducible PF02519.14 GAX11203.1 - 0.062 13.5 1.2 1.8 8.8 0.4 2.6 2 1 0 2 2 2 0 Auxin responsive protein UPF0242 PF06785.11 GAX11203.1 - 1.1 9.3 10.6 1.2 9.2 3.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 GAX11203.1 - 1.4 9.2 9.7 5.5 7.3 2.7 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 GAX11203.1 - 1.6 8.9 11.6 5.3 7.2 0.5 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TSC22 PF01166.18 GAX11203.1 - 3.2 8.1 8.3 4 7.8 0.7 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF4164 PF13747.6 GAX11203.1 - 9.5 6.6 13.8 1.4 9.3 2.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) GrpE PF01025.19 GAX11204.1 - 5.7e-18 65.1 4.0 1.7e-17 63.6 4.0 1.7 1 1 0 1 1 1 1 GrpE Prefoldin PF02996.17 GAX11204.1 - 0.006 16.5 0.8 3.3 7.7 0.0 2.4 2 0 0 2 2 2 2 Prefoldin subunit Sin_N PF04801.13 GAX11204.1 - 0.066 12.4 4.2 0.086 12.0 4.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF4407 PF14362.6 GAX11204.1 - 0.07 12.5 4.2 0.098 12.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4763 PF15960.5 GAX11204.1 - 0.073 12.4 4.2 0.11 11.8 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Cnn_1N PF07989.11 GAX11204.1 - 0.16 12.2 3.9 0.34 11.1 3.9 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 GAX11204.1 - 0.26 10.1 7.4 0.34 9.7 7.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 GAX11204.1 - 2.1 8.1 5.1 3.8 7.4 5.0 1.6 1 1 0 1 1 1 0 Septum formation initiator G-patch PF01585.23 GAX11205.1 - 3e-08 33.4 0.7 3e-06 27.0 0.1 2.5 2 0 0 2 2 2 2 G-patch domain G-patch_2 PF12656.7 GAX11205.1 - 3.9e-06 26.9 1.2 3.9e-06 26.9 1.2 3.3 3 1 0 3 3 3 1 G-patch domain PRP38 PF03371.15 GAX11206.1 - 2.6e-41 141.4 0.0 3.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 PRP38 family DUF411 PF04214.13 GAX11206.1 - 0.15 12.0 0.0 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF Presenilin PF01080.17 GAX11206.1 - 3.9 6.1 6.6 5.1 5.7 6.6 1.1 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 GAX11208.1 - 1.4e-35 120.9 0.0 1.2e-17 63.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX11208.1 - 7.1e-07 29.3 0.0 0.015 15.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GAX11208.1 - 0.0032 17.4 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif IF2_N PF04760.15 GAX11208.1 - 0.0039 17.0 3.3 0.0039 17.0 3.3 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region RRM_occluded PF16842.5 GAX11208.1 - 0.073 12.9 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif dsDNA_bind PF01984.20 GAX11210.1 - 0.063 13.5 1.1 3 8.1 1.1 2.4 2 1 0 2 2 2 0 Double-stranded DNA-binding domain Mito_morph_reg PF14972.6 GAX11211.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator SR1P PF13790.6 GAX11213.1 - 0.22 11.7 0.1 0.22 11.7 0.1 1.7 2 0 0 2 2 2 0 SR1 protein Glyco_trans_2_3 PF13632.6 GAX11214.1 - 1.1 9.2 8.5 2.5 7.9 8.5 1.7 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Ins134_P3_kin PF05770.11 GAX11216.1 - 5.6e-30 104.4 0.0 1.6e-29 102.9 0.0 1.8 1 1 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain TTL PF03133.15 GAX11216.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Peptidase_C12 PF01088.21 GAX11217.1 - 3.6e-60 203.3 0.1 6.7e-60 202.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 GAX11217.1 - 7.5e-17 61.0 3.0 7.5e-17 61.0 3.0 2.3 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolases PolyA_pol PF01743.20 GAX11218.1 - 1.3e-20 74.2 0.0 2.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 GAX11218.1 - 0.079 13.0 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative zf-C3HC4_3 PF13920.6 GAX11219.1 - 8.7e-08 31.9 8.0 8.7e-08 31.9 8.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX11219.1 - 0.00011 22.0 9.1 0.00011 22.0 9.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX11219.1 - 0.00039 20.7 9.1 0.00039 20.7 9.1 2.7 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 GAX11219.1 - 0.0021 18.0 8.6 0.0021 18.0 8.6 3.3 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAX11219.1 - 0.003 17.4 7.1 0.003 17.4 7.1 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 GAX11219.1 - 0.6 10.1 8.6 0.028 14.4 1.6 2.3 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) Chloroa_b-bind PF00504.21 GAX11220.1 - 1.7e-28 100.2 0.0 4e-28 99.0 0.0 1.6 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Guanylate_cyc PF00211.20 GAX11221.1 - 4.8e-52 176.3 0.0 8.4e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 GAX11221.1 - 6.7e-30 104.2 0.0 1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 GAX11221.1 - 8.1e-15 54.8 4.9 1.8e-07 30.8 0.1 2.7 2 1 1 3 3 3 2 Heme NO binding associated Pyr_redox_2 PF07992.14 GAX11222.1 - 1.3e-46 159.2 0.1 2.2e-46 158.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 GAX11222.1 - 1.8e-19 69.6 0.0 6.7e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 GAX11222.1 - 1.5e-16 60.3 0.0 2.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 GAX11222.1 - 6.3e-16 58.7 1.3 1.2e-12 48.2 0.4 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 GAX11222.1 - 4e-14 52.7 6.0 6e-10 39.3 4.8 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 GAX11222.1 - 5.6e-11 42.2 0.0 1.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 GAX11222.1 - 4.1e-10 39.4 0.0 9.4e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 GAX11222.1 - 9.5e-08 31.9 0.0 2.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain AlaDh_PNT_C PF01262.21 GAX11222.1 - 0.00072 18.9 0.0 0.021 14.1 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAX11222.1 - 0.0021 17.2 0.4 0.17 10.9 0.5 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 GAX11222.1 - 0.0026 17.0 0.0 1.1 8.3 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAX11222.1 - 0.003 16.9 0.3 1.2 8.3 0.5 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAX11222.1 - 0.16 12.4 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 GAX11222.1 - 0.25 10.4 1.3 4.9 6.1 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain PI3_PI4_kinase PF00454.27 GAX11223.1 - 4.4e-27 95.5 0.0 4.7e-26 92.1 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PDZ_6 PF17820.1 GAX11223.1 - 8e-05 22.4 0.4 0.017 14.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 GAX11223.1 - 0.002 18.5 0.1 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX11223.1 - 0.0084 16.4 0.0 0.034 14.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Sec3_C PF09763.9 GAX11223.1 - 0.14 10.5 1.9 1 7.7 0.0 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 TLD PF07534.16 GAX11224.1 - 1.9e-22 80.0 0.0 4.3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 TLD Glyco_transf_34 PF05637.12 GAX11225.1 - 4.4e-19 69.1 3.4 1.3e-10 41.4 1.5 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GAX11225.1 - 6.9e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 GAX11225.1 - 0.00014 21.9 0.6 0.00022 21.3 0.6 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase ABC_membrane PF00664.23 GAX11226.1 - 6.5e-63 212.9 29.1 1e-33 117.2 7.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX11226.1 - 6.9e-46 156.2 1.3 1.3e-26 93.7 0.1 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAX11226.1 - 1e-11 44.7 2.7 0.00028 20.4 0.1 4.4 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAX11226.1 - 4.4e-06 26.8 1.1 0.17 11.9 0.0 3.9 4 0 0 4 4 3 2 50S ribosome-binding GTPase DUF87 PF01935.17 GAX11226.1 - 1.6e-05 25.1 0.6 0.017 15.2 0.0 2.9 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_29 PF13555.6 GAX11226.1 - 0.00026 20.6 1.6 0.22 11.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GAX11226.1 - 0.0029 17.5 1.2 1.6 8.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 GAX11226.1 - 0.0032 16.8 0.5 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 GAX11226.1 - 0.0035 17.8 0.0 4.3 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX11226.1 - 0.0036 17.6 0.6 5.9 7.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAX11226.1 - 0.0084 16.0 0.6 1.9 8.3 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 GAX11226.1 - 0.0094 15.0 0.3 2.7 7.0 0.1 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 GAX11226.1 - 0.01 14.8 0.0 2.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 GAX11226.1 - 0.011 15.6 1.1 0.13 12.1 0.2 3.0 3 1 0 3 3 3 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 GAX11226.1 - 0.025 14.6 0.2 0.025 14.6 0.2 3.3 4 0 0 4 4 3 0 Dynamin family RNA_helicase PF00910.22 GAX11226.1 - 0.03 14.7 0.2 8.8 6.8 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 GAX11226.1 - 0.03 13.8 0.1 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PARM PF17061.5 GAX11226.1 - 0.069 13.3 1.1 0.15 12.2 1.1 1.5 1 0 0 1 1 1 0 PARM DUF3874 PF12990.7 GAX11226.1 - 0.083 13.2 0.2 0.26 11.7 0.2 1.9 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) cobW PF02492.19 GAX11226.1 - 0.091 12.3 3.0 10 5.6 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 GAX11226.1 - 0.11 12.3 0.2 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 GAX11226.1 - 0.11 12.4 0.5 7.5 6.4 0.0 3.0 3 0 0 3 3 3 0 NACHT domain ATPase_2 PF01637.18 GAX11226.1 - 0.16 11.9 0.8 7.3 6.4 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 GAX11226.1 - 0.42 10.3 3.1 1.9 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Multi_Drug_Res PF00893.19 GAX11226.1 - 0.6 10.8 4.9 3.4 8.4 0.8 3.1 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF3987 PF13148.6 GAX11226.1 - 6 5.8 5.9 35 3.3 4.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PAPS_reduct PF01507.19 GAX11227.1 - 1.1e-26 93.9 0.0 2.3e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 GAX11227.1 - 9.6e-09 35.2 0.1 2.1e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX11227.1 - 0.0055 17.1 0.1 0.016 15.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Acetyltransf_1 PF00583.25 GAX11228.1 - 1.2e-09 38.4 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family LCM PF04072.14 GAX11228.1 - 3.6e-09 36.8 0.0 7.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_7 PF13508.7 GAX11228.1 - 4.4e-09 36.6 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX11228.1 - 6.9e-08 32.5 0.0 1.8e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAX11228.1 - 0.0049 16.6 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 GAX11228.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Abhydrolase_3 PF07859.13 GAX11229.1 - 5.5e-22 78.7 0.0 7.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Eno-Rase_NADH_b PF12242.8 GAX11229.1 - 0.0014 18.4 0.1 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PC-Esterase PF13839.6 GAX11230.1 - 0.0079 16.0 0.0 0.036 13.8 0.0 1.9 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p FHA PF00498.26 GAX11231.1 - 0.0014 18.9 0.0 0.0046 17.3 0.0 1.8 1 1 0 1 1 1 1 FHA domain VWD PF00094.25 GAX11232.1 - 0.00013 22.3 0.0 0.00025 21.4 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type D domain RGM_C PF06534.13 GAX11232.1 - 0.003 17.1 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus DUF4813 PF16072.5 GAX11232.1 - 6.6 6.3 40.9 10 5.7 40.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) NAD_binding_4 PF07993.12 GAX11233.1 - 1.1e-44 152.5 0.0 2e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein FAD-oxidase_C PF02913.19 GAX11233.1 - 5.1e-35 121.3 0.0 1.3e-34 120.0 0.0 1.7 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAX11233.1 - 2.8e-34 117.8 0.0 6.6e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ACBP PF00887.19 GAX11233.1 - 1.2e-19 70.3 0.4 2.6e-19 69.2 0.1 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein DegT_DnrJ_EryC1 PF01041.17 GAX11233.1 - 2.3e-19 69.9 0.1 6.1e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Acyltransferase PF01553.21 GAX11233.1 - 4.4e-18 65.2 0.0 1.1e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase Epimerase PF01370.21 GAX11233.1 - 1.1e-07 31.5 0.1 5.6e-07 29.3 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX11233.1 - 3.8e-07 29.8 0.0 6.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAX11233.1 - 0.00026 20.2 0.2 0.0058 15.8 0.2 2.8 1 1 0 1 1 1 1 RmlD substrate binding domain Beta_elim_lyase PF01212.21 GAX11233.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PDZ_6 PF17820.1 GAX11234.1 - 8.8e-08 31.9 0.0 2.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX11234.1 - 8.2e-06 26.1 0.0 2.8e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX11234.1 - 0.002 18.4 0.2 0.012 15.9 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Fez1 PF06818.15 GAX11234.1 - 0.0091 16.5 19.1 0.0091 16.5 19.1 13.1 2 1 11 14 14 14 4 Fez1 Tricorn_PDZ PF14685.6 GAX11234.1 - 0.054 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain PikAIV_N PF18605.1 GAX11234.1 - 0.31 10.6 15.3 0.026 14.1 1.6 4.9 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HTH_54 PF18607.1 GAX11234.1 - 2.5 8.2 8.8 0.59 10.2 1.6 4.0 3 0 0 3 3 3 0 ParA helix turn helix domain PDZ_4 PF17816.1 GAX11234.1 - 3 8.3 0.0 3 8.3 0.0 3.8 4 0 0 4 4 4 0 PDZ domain Acyltransferase PF01553.21 GAX11235.1 - 2.2e-25 88.8 0.0 4.1e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ribosomal_L19 PF01245.20 GAX11236.1 - 1.3e-18 67.0 0.3 1.9e-18 66.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 NFACT-R_2 PF18297.1 GAX11236.1 - 0.0027 17.9 0.1 0.004 17.3 0.1 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF563 PF04577.14 GAX11238.1 - 3.9e-18 66.3 0.0 4.9e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) tRNA-synt_2b PF00587.25 GAX11240.1 - 2.4e-21 76.5 0.0 4.1e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 GAX11240.1 - 8.1e-20 70.8 0.3 8.1e-20 70.8 0.3 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 GAX11240.1 - 4.8e-13 49.1 0.3 1.1e-12 47.9 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 GAX11240.1 - 2.1e-09 37.4 0.8 2.1e-09 37.4 0.8 1.7 2 0 0 2 2 2 1 WHEP-TRS domain ABC_tran_CTD PF16326.5 GAX11240.1 - 0.088 13.1 1.9 0.35 11.1 1.9 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain FadA PF09403.10 GAX11240.1 - 0.15 12.5 1.1 0.56 10.7 1.1 2.0 1 0 0 1 1 1 0 Adhesion protein FadA HalX PF08663.10 GAX11240.1 - 0.27 11.6 5.7 8.6 6.8 0.4 3.6 3 1 1 4 4 4 0 HalX domain Pkinase PF00069.25 GAX11241.1 - 1.3e-23 83.7 0.0 1.5e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11241.1 - 1.3e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX11241.1 - 1.1e-06 27.8 0.0 1.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX11241.1 - 4e-05 23.7 0.1 0.0034 17.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX11241.1 - 0.095 12.3 0.0 9 5.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 GAX11241.1 - 0.17 11.2 0.2 0.3 10.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_1_2 PF00155.21 GAX11244.1 - 2.1e-51 175.3 0.0 2.4e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX11244.1 - 1.7e-07 30.1 0.0 2.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAX11244.1 - 2e-05 24.1 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAX11244.1 - 0.0045 16.0 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 GAX11244.1 - 0.033 13.0 0.0 0.063 12.1 0.0 1.5 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase HIG_1_N PF04588.13 GAX11245.1 - 0.0062 16.7 3.6 0.0071 16.6 0.0 2.6 2 1 1 3 3 3 1 Hypoxia induced protein conserved region P-mevalo_kinase PF04275.14 GAX11245.1 - 0.0062 16.5 0.5 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Phosphomevalonate kinase Cytidylate_kin2 PF13189.6 GAX11245.1 - 0.014 15.5 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_16 PF13191.6 GAX11246.1 - 7.3e-05 23.2 0.0 0.012 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 GAX11246.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA PF00004.29 GAX11246.1 - 0.021 15.2 0.0 0.095 13.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX11246.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain 2OG-FeII_Oxy_3 PF13640.6 GAX11248.1 - 9.7e-16 58.4 0.1 2.6e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX11248.1 - 3.6e-05 24.2 0.0 0.0002 21.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily VHL PF01847.16 GAX11248.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 VHL beta domain UspB PF10625.9 GAX11248.1 - 0.075 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Universal stress protein B (UspB) Helicase_C_2 PF13307.6 GAX11249.1 - 1.5e-48 165.2 0.0 4.2e-48 163.7 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAX11249.1 - 6.2e-40 136.7 0.0 2.7e-39 134.6 0.0 2.1 3 0 0 3 3 3 1 DEAD_2 ResIII PF04851.15 GAX11249.1 - 0.0022 18.0 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX11249.1 - 0.0075 16.5 0.1 1.2 9.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 GAX11249.1 - 0.044 13.2 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Synaphin PF05835.12 GAX11249.1 - 0.31 11.3 2.2 0.72 10.1 2.2 1.5 1 0 0 1 1 1 0 Synaphin protein GP63 PF17471.2 GAX11249.1 - 4.8 7.4 6.3 4.6 7.5 2.0 2.6 1 1 1 2 2 2 0 Gene product 63 HSF_DNA-bind PF00447.17 GAX11250.1 - 1e-29 103.0 0.4 1.5e-29 102.4 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Leu_zip PF15294.6 GAX11250.1 - 0.0042 16.7 0.8 0.0067 16.0 0.8 1.3 1 0 0 1 1 1 1 Leucine zipper VASP_tetra PF08776.11 GAX11250.1 - 0.0081 15.7 0.5 0.017 14.7 0.5 1.5 1 0 0 1 1 1 1 VASP tetramerisation domain Mod_r PF07200.13 GAX11250.1 - 0.016 15.3 0.8 0.028 14.5 0.8 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FAM184 PF15665.5 GAX11250.1 - 0.019 14.8 0.4 0.026 14.3 0.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Bacillus_HBL PF05791.11 GAX11250.1 - 0.049 13.4 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) 2OG-FeII_Oxy_3 PF13640.6 GAX11251.1 - 1.8e-14 54.4 0.0 4.2e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.19 GAX11252.1 - 4.6e-41 140.8 0.0 1.2e-39 136.1 0.0 2.1 1 1 0 1 1 1 1 Actin PRP1_N PF06424.12 GAX11252.1 - 0.0035 17.8 6.5 0.0074 16.7 6.5 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal MreB_Mbl PF06723.13 GAX11252.1 - 0.2 10.4 0.0 0.4 9.4 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein Nop14 PF04147.12 GAX11252.1 - 0.21 9.8 12.6 0.29 9.3 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAX11252.1 - 0.25 9.6 10.5 0.36 9.1 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GAX11252.1 - 1.1 9.3 23.3 1.9 8.6 23.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GAX11252.1 - 1.2 8.9 20.9 1.8 8.2 20.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.13 GAX11252.1 - 6.4 5.2 15.3 9.2 4.7 15.3 1.1 1 0 0 1 1 1 0 Utp14 protein TPR_12 PF13424.6 GAX11253.1 - 3.8e-88 289.8 25.3 1.3e-15 57.5 0.0 9.9 5 3 5 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.28 GAX11253.1 - 3e-56 185.1 12.5 4.1e-05 23.2 0.0 15.1 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_10 PF13374.6 GAX11253.1 - 5.3e-52 172.4 19.5 6.2e-06 25.9 0.2 13.7 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_2 PF07719.17 GAX11253.1 - 2.4e-45 149.0 22.3 0.00073 19.5 0.0 15.3 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11253.1 - 1.6e-36 121.5 23.1 0.0028 17.7 0.0 14.0 14 0 0 14 14 13 9 Tetratricopeptide repeat TPR_7 PF13176.6 GAX11253.1 - 1.4e-33 112.4 16.2 7.6e-05 22.5 0.1 13.4 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_11 PF13414.6 GAX11253.1 - 1.6e-21 75.7 7.5 0.0092 15.6 0.0 10.4 10 1 0 10 10 10 5 TPR repeat NB-ARC PF00931.22 GAX11253.1 - 8e-17 61.3 0.0 1.7e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 GAX11253.1 - 2.8e-16 59.8 12.2 0.0038 16.7 0.0 5.6 1 1 5 6 6 6 5 MalT-like TPR region TPR_14 PF13428.6 GAX11253.1 - 7.3e-12 45.1 11.4 34 5.6 0.0 12.3 9 3 3 12 12 12 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX11253.1 - 1.2e-09 38.2 12.7 14 6.6 0.0 11.6 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX11253.1 - 4.6e-07 30.4 0.1 0.017 15.7 0.0 7.2 8 1 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX11253.1 - 1.1e-06 28.6 2.4 17 6.1 0.0 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat AAA_16 PF13191.6 GAX11253.1 - 2.7e-05 24.6 0.0 0.00011 22.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain ANAPC3 PF12895.7 GAX11253.1 - 0.003 17.7 8.9 6.3 7.1 0.0 6.2 6 0 0 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAX11253.1 - 0.0072 16.8 13.6 23 5.6 0.0 7.9 7 1 2 9 9 9 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX11253.1 - 0.014 14.8 4.3 25 4.4 0.0 5.7 7 0 0 7 7 7 0 SHNi-TPR DUF627 PF04781.12 GAX11253.1 - 0.015 15.3 5.1 13 5.8 0.0 5.7 5 1 0 5 5 5 0 Protein of unknown function (DUF627) DUF5113 PF17140.4 GAX11253.1 - 0.033 14.0 0.4 42 3.9 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF5113) TPR_5 PF12688.7 GAX11253.1 - 0.049 13.9 1.3 9.3 6.5 0.0 4.8 5 1 0 5 5 4 0 Tetratrico peptide repeat ANAPC5 PF12862.7 GAX11253.1 - 0.06 13.4 16.1 4.7 7.3 0.2 7.5 4 3 2 6 6 6 0 Anaphase-promoting complex subunit 5 TetR_C_19 PF17924.1 GAX11253.1 - 0.14 12.7 1.4 17 6.0 0.1 3.5 3 0 0 3 3 2 0 Tetracyclin repressor-like, C-terminal domain PPR PF01535.20 GAX11253.1 - 0.47 10.8 7.9 63 4.1 0.2 6.4 6 0 0 6 6 5 0 PPR repeat MIT PF04212.18 GAX11253.1 - 1.2 9.3 16.3 37 4.5 0.0 8.8 10 1 0 11 11 10 0 MIT (microtubule interacting and transport) domain Armet PF10208.9 GAX11254.1 - 3.2e-30 105.0 9.8 4.9e-30 104.4 9.8 1.2 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 GAX11254.1 - 0.00077 19.2 0.1 0.0016 18.1 0.1 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 GAX11254.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Uteroglobin PF01099.17 GAX11254.1 - 0.037 14.4 0.6 0.092 13.1 0.6 1.7 1 0 0 1 1 1 0 Uteroglobin family DHR10 PF18595.1 GAX11254.1 - 0.99 9.5 5.0 3.3 7.8 0.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain AAA PF00004.29 GAX11255.1 - 2.4e-36 125.1 0.0 5.3e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX11255.1 - 1.8e-08 34.1 0.0 5.7e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAX11255.1 - 6.2e-05 22.8 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 GAX11255.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 GAX11255.1 - 0.0004 20.6 0.0 0.0034 17.5 0.0 2.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX11255.1 - 0.00043 20.6 0.7 0.019 15.2 0.2 3.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX11255.1 - 0.00099 19.1 0.1 0.0061 16.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX11255.1 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAX11255.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 GAX11255.1 - 0.0018 18.7 8.0 0.064 13.6 0.8 5.6 4 1 0 4 4 4 1 AAA ATPase domain AAA_14 PF13173.6 GAX11255.1 - 0.0038 17.2 0.0 0.04 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAX11255.1 - 0.0046 16.4 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAX11255.1 - 0.0067 17.0 0.3 0.12 12.9 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 GAX11255.1 - 0.018 14.8 0.1 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 GAX11255.1 - 0.02 14.1 0.2 0.047 12.9 0.1 1.6 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 GAX11255.1 - 0.057 13.7 0.6 0.55 10.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 GAX11255.1 - 0.096 13.0 3.2 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain HRDC PF00570.23 GAX11256.1 - 0.009 16.0 1.9 0.086 12.8 0.2 2.7 2 0 0 2 2 2 1 HRDC domain Glyco_hydro_114 PF03537.13 GAX11256.1 - 0.05 12.9 2.2 0.066 12.5 2.2 1.2 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 ATG16 PF08614.11 GAX11256.1 - 0.24 11.6 48.8 2.3 8.4 6.6 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TPK_catalytic PF04263.16 GAX11256.1 - 0.69 10.0 4.5 0.37 10.8 0.6 2.1 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DUF3644 PF12358.8 GAX11256.1 - 0.73 10.4 3.9 5.7 7.5 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3644) DASH_Dam1 PF08653.10 GAX11256.1 - 1.7 8.5 13.7 0.76 9.6 0.5 4.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 HisKA_2 PF07568.12 GAX11256.1 - 5.9 7.0 11.0 0.082 13.0 1.1 2.8 3 1 0 3 3 3 0 Histidine kinase ArAE_2_N PF10337.9 GAX11256.1 - 7.1 5.5 14.6 9.4 5.1 14.2 1.4 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Serine_rich PF08824.10 GAX11257.1 - 0.00048 20.2 3.1 0.00048 20.2 3.1 3.9 4 1 0 4 4 4 1 Serine rich protein interaction domain DUF3450 PF11932.8 GAX11257.1 - 0.0059 15.9 6.7 0.0059 15.9 6.7 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF3450) KxDL PF10241.9 GAX11257.1 - 0.033 14.4 1.6 0.033 14.4 1.6 5.9 3 2 2 5 5 5 0 Uncharacterized conserved protein WXG100 PF06013.12 GAX11257.1 - 0.041 14.1 19.8 0.21 11.8 1.2 5.3 3 2 2 5 5 5 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 GAX11257.1 - 0.07 13.3 32.4 0.036 14.2 4.9 4.7 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Gp_dh_C PF02800.20 GAX11258.1 - 5.5e-66 221.0 0.0 7.8e-66 220.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX11258.1 - 4.7e-35 120.0 0.0 9.2e-35 119.0 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX11258.1 - 0.015 15.4 0.1 0.063 13.4 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF4451 PF14616.6 GAX11258.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) 2-Hacid_dh_C PF02826.19 GAX11258.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA_18 PF13238.6 GAX11262.1 - 0.0043 17.6 0.0 0.0094 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX11262.1 - 0.0059 17.0 0.1 0.18 12.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 GAX11262.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 GAX11262.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAX11262.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 GAX11262.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 GAX11262.1 - 0.02 14.1 0.0 0.057 12.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain CoaE PF01121.20 GAX11262.1 - 0.023 14.4 0.4 0.17 11.5 0.4 2.1 1 1 0 1 1 1 0 Dephospho-CoA kinase NACHT PF05729.12 GAX11262.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 GAX11262.1 - 0.027 14.7 0.1 0.11 12.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain DUF3987 PF13148.6 GAX11262.1 - 0.03 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_29 PF13555.6 GAX11262.1 - 0.047 13.4 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 GAX11262.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX11262.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 GAX11262.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAX11262.1 - 0.13 12.4 2.7 0.35 11.0 0.5 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX11262.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 GAX11262.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 2OG-FeII_Oxy_3 PF13640.6 GAX11263.1 - 1.7e-13 51.2 0.0 3.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily peroxidase PF00141.23 GAX11264.1 - 1.3e-17 64.3 0.0 1.9e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase PreAtp-grasp PF18604.1 GAX11265.1 - 0.036 13.7 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 Pre ATP-grasp domain Arm PF00514.23 GAX11265.1 - 0.58 10.3 6.7 11 6.2 0.1 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ATP-grasp_5 PF13549.6 GAX11266.1 - 1.2e-75 253.8 0.0 1.8e-75 253.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 GAX11266.1 - 5.5e-50 168.8 0.1 1.8e-49 167.1 0.1 2.0 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAX11266.1 - 4e-25 88.5 0.5 6.1e-24 84.7 0.1 3.1 3 1 1 4 4 4 1 CoA binding domain CoA_binding PF02629.19 GAX11266.1 - 9e-12 45.5 0.1 3.2e-11 43.7 0.1 2.0 1 0 0 1 1 1 1 CoA binding domain DFRP_C PF16543.5 GAX11268.1 - 2.1e-14 53.7 5.7 2.1e-14 53.7 5.7 3.4 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 DUF4718 PF15842.5 GAX11268.1 - 2.7 7.7 10.6 0.39 10.5 6.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Lipase_GDSL_3 PF14606.6 GAX11268.1 - 6.9 6.8 9.6 0.58 10.3 0.1 3.0 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase family DUF4122 PF13498.6 GAX11269.1 - 0.029 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) LZ_Tnp_IS481 PF13011.6 GAX11269.1 - 0.078 13.5 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 MAD PF05557.13 GAX11269.1 - 0.09 11.1 0.1 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Metal_resist PF13801.6 GAX11269.1 - 0.26 11.5 0.1 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance CMAS PF02353.20 GAX11270.1 - 6.4e-83 278.2 0.0 8.5e-83 277.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 GAX11270.1 - 2.2e-14 53.9 0.0 6e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX11270.1 - 3.3e-13 50.2 0.0 6.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX11270.1 - 1.7e-12 47.5 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX11270.1 - 1.7e-08 35.1 0.0 6e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX11270.1 - 6.3e-08 32.5 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 GAX11270.1 - 0.0002 21.1 0.0 0.0086 15.7 0.0 2.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 GAX11270.1 - 0.0019 17.8 0.0 0.0055 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 GAX11270.1 - 0.0028 17.4 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 GAX11270.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 GAX11270.1 - 0.068 12.2 0.2 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 GAX11270.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase ABC1 PF03109.16 GAX11271.1 - 1.8e-22 79.7 0.0 3.8e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family SpoU_methylase PF00588.19 GAX11272.1 - 4.4e-22 78.8 0.0 7.2e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family THOC7 PF05615.13 GAX11273.1 - 0.012 15.9 9.4 0.012 15.9 9.4 3.6 4 1 1 5 5 5 0 Tho complex subunit 7 TPR_2 PF07719.17 GAX11273.1 - 0.16 12.2 0.4 4.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4196 PF13846.6 GAX11273.1 - 1.2 9.3 9.1 0.51 10.6 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) SOUL PF04832.12 GAX11275.1 - 0.00064 19.9 0.0 0.002 18.3 0.0 1.8 1 1 0 1 1 1 1 SOUL heme-binding protein Peptidase_S8 PF00082.22 GAX11277.1 - 9.3e-40 136.7 3.1 1.3e-39 136.3 3.1 1.2 1 0 0 1 1 1 1 Subtilase family Sec23_BS PF08033.12 GAX11278.1 - 2.1e-14 54.0 0.0 3.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 GAX11278.1 - 9.1e-10 38.5 0.0 2.2e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX11278.1 - 8.8e-08 31.9 0.1 1.7e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 GAX11278.1 - 7.8e-06 25.7 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 GAX11278.1 - 0.015 15.3 2.4 0.04 14.0 2.4 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger ubiquitin PF00240.23 GAX11282.1 - 3.8e-24 84.2 0.4 4.2e-24 84.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX11282.1 - 4.8e-13 48.7 0.3 5.3e-13 48.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAX11282.1 - 1.7e-06 28.3 0.1 2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 GAX11282.1 - 7.3e-05 23.2 0.2 0.00027 21.4 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX11282.1 - 0.00099 19.2 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAX11282.1 - 0.026 15.1 0.0 0.031 14.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Dynamin_N PF00350.23 GAX11283.1 - 5.9e-11 42.7 0.0 1.5e-07 31.6 0.0 2.4 1 1 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 GAX11283.1 - 2.6e-06 27.5 0.0 1.2e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX11283.1 - 0.00012 22.0 0.0 0.41 10.5 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 GAX11283.1 - 0.00059 20.3 0.2 0.17 12.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AIG1 PF04548.16 GAX11283.1 - 0.0085 15.4 0.0 0.2 11.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 GAX11283.1 - 0.015 14.9 0.1 0.83 9.2 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Roc PF08477.13 GAX11283.1 - 0.11 12.7 0.0 0.71 10.1 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Fasciclin PF02469.22 GAX11285.1 - 4.6e-19 68.9 0.0 1.7e-06 28.3 0.1 4.6 4 0 0 4 4 4 4 Fasciclin domain DUF525 PF04379.14 GAX11285.1 - 2.2e-17 63.0 0.0 4.7e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 ApaG domain Aa_trans PF01490.18 GAX11286.1 - 4e-16 58.7 19.3 4.4e-06 25.7 3.0 3.1 2 1 1 3 3 3 3 Transmembrane amino acid transporter protein DUF4817 PF16087.5 GAX11286.1 - 0.074 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Herpes_UL42 PF02282.16 GAX11286.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) PGK PF00162.19 GAX11288.1 - 2.4e-132 441.5 0.1 3e-132 441.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase MTS PF05175.14 GAX11288.1 - 0.014 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Nitro_FeMo-Co PF02579.17 GAX11288.1 - 0.081 13.3 0.2 0.84 10.0 0.0 2.6 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor TRAM_LAG1_CLN8 PF03798.16 GAX11289.1 - 1.1e-07 31.8 4.9 1.1e-07 31.8 4.9 1.8 1 1 1 2 2 2 1 TLC domain DUF4234 PF14018.6 GAX11289.1 - 0.11 12.6 4.3 0.36 11.0 2.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) EamA PF00892.20 GAX11294.1 - 9.3e-09 35.6 7.9 9.3e-09 35.6 7.9 3.0 2 1 0 2 2 2 2 EamA-like transporter family Toxin_35 PF10530.9 GAX11296.1 - 9.4e-05 22.3 5.8 9.4e-05 22.3 5.8 14.2 4 3 10 14 14 14 3 Toxin with inhibitor cystine knot ICK or Knottin scaffold CBM_14 PF01607.24 GAX11297.1 - 1.3e-06 28.4 5.6 1.3e-06 28.4 5.6 3.2 2 1 1 3 3 3 1 Chitin binding Peritrophin-A domain VTC PF09359.10 GAX11298.1 - 7.8e-71 238.7 1.0 7.8e-71 238.7 1.0 1.8 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 GAX11298.1 - 2.7e-11 43.7 1.4 2.7e-11 43.7 1.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAX11298.1 - 1.4e-07 31.8 9.2 0.0011 19.0 4.1 3.3 1 1 2 3 3 3 3 SPX domain LemA PF04011.12 GAX11298.1 - 0.068 13.0 1.4 0.09 12.6 0.3 1.7 2 0 0 2 2 2 0 LemA family C_Hendra PF16821.5 GAX11298.1 - 0.41 10.5 4.0 0.11 12.4 0.3 1.8 2 0 0 2 2 2 0 C protein from hendra and measles viruses Ribosomal_S6e PF01092.19 GAX11299.1 - 6.3e-49 165.1 0.9 1.8e-48 163.7 0.9 1.8 1 0 0 1 1 1 1 Ribosomal protein S6e ECH_1 PF00378.20 GAX11299.1 - 0.017 14.4 0.2 0.027 13.8 0.2 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Mito_carr PF00153.27 GAX11300.1 - 3.8e-52 174.2 8.3 6.7e-20 70.8 0.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_3 PF07859.13 GAX11300.1 - 0.02 14.8 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3043 PF11241.8 GAX11301.1 - 0.0019 18.2 1.5 0.006 16.6 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3043) DUF4017 PF13209.6 GAX11301.1 - 0.1 12.6 1.6 1.3 9.0 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4017) Ank_2 PF12796.7 GAX11302.1 - 8.3e-39 132.1 4.2 6.8e-07 29.8 0.4 9.9 3 1 7 11 11 11 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX11302.1 - 1.1e-27 93.0 16.4 0.25 12.0 0.0 15.3 16 0 0 16 16 16 10 Ankyrin repeat Ank PF00023.30 GAX11302.1 - 1.2e-26 92.0 24.2 0.22 12.0 0.0 15.8 16 0 0 16 16 16 7 Ankyrin repeat Ank_4 PF13637.6 GAX11302.1 - 2.3e-26 91.8 14.9 8.7e-05 23.0 0.3 12.9 8 5 4 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX11302.1 - 3.6e-25 87.7 18.2 0.0032 17.7 0.2 13.7 11 4 4 15 15 15 8 Ankyrin repeats (many copies) DUF572 PF04502.13 GAX11303.1 - 1.4e-59 202.4 11.1 2.3e-59 201.7 11.1 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) Taq-exonuc PF09281.10 GAX11303.1 - 0.55 10.2 3.7 0.48 10.4 0.1 2.2 2 0 0 2 2 2 0 Taq polymerase, exonuclease DUF285 PF03382.14 GAX11304.1 - 8.1e-53 177.3 25.1 1.8e-27 95.5 6.6 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 HEAT PF02985.22 GAX11305.1 - 3.1e-14 51.8 10.1 0.023 14.9 0.1 7.6 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 GAX11305.1 - 3.3e-08 33.8 12.1 0.0073 16.7 0.8 6.8 6 1 1 7 7 7 3 HEAT repeats PDZ_6 PF17820.1 GAX11305.1 - 2.1e-07 30.7 0.0 5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Arm PF00514.23 GAX11305.1 - 1.2e-05 25.2 1.3 2.7 8.2 0.0 4.2 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 GAX11305.1 - 2.3e-05 24.5 2.3 0.94 9.5 0.0 4.4 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX11305.1 - 3.8e-05 24.1 9.2 0.34 11.5 0.3 6.0 5 1 1 6 6 6 2 HEAT-like repeat PDZ_2 PF13180.6 GAX11305.1 - 0.00044 20.5 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX11305.1 - 0.00058 20.2 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DNA_alkylation PF08713.11 GAX11305.1 - 0.039 13.6 0.1 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 DNA alkylation repair enzyme BSD PF03909.17 GAX11306.1 - 2.2e-11 43.6 2.7 5.6e-08 32.7 0.6 3.4 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 GAX11306.1 - 1.3e-08 35.0 0.2 2.9e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DnaJ PF00226.31 GAX11307.1 - 5.8e-19 68.0 1.1 1.1e-18 67.1 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain TrmO PF01980.16 GAX11308.1 - 3.9e-35 120.6 0.0 8e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 GAX11308.1 - 0.06 13.5 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 TrmO C-terminal domain TBPIP PF07106.13 GAX11308.1 - 0.092 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain PGA2 PF07543.12 GAX11309.1 - 0.027 14.5 2.6 0.062 13.3 2.6 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 DHR10 PF18595.1 GAX11309.1 - 0.15 12.1 7.0 0.46 10.6 7.0 1.8 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain WLM PF08325.10 GAX11310.1 - 6.1e-32 111.3 1.7 7.2e-31 107.7 1.7 2.1 1 1 0 1 1 1 1 WLM domain TnpV PF14198.6 GAX11310.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Reprolysin_5 PF13688.6 GAX11310.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12 CbiG_N PF11760.8 GAX11310.1 - 0.14 12.1 0.0 0.72 9.9 0.0 2.0 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal PTEN_C2 PF10409.9 GAX11313.1 - 9e-20 70.8 0.0 2.2e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.6 GAX11313.1 - 0.16 12.1 1.9 0.54 10.4 0.0 2.6 3 0 0 3 3 3 0 Inositol hexakisphosphate vATP-synt_E PF01991.18 GAX11313.1 - 0.88 8.9 5.4 2.5 7.4 3.7 2.3 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit MPP6 PF10175.9 GAX11314.1 - 0.13 12.8 0.2 0.13 12.8 0.2 3.4 3 1 0 3 3 3 0 M-phase phosphoprotein 6 Nuc_sug_transp PF04142.15 GAX11316.1 - 2e-27 96.2 9.6 2.6e-27 95.8 9.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAX11316.1 - 0.1 12.8 26.5 0.062 13.5 8.2 2.6 2 1 0 2 2 2 0 EamA-like transporter family Nuc_sug_transp PF04142.15 GAX11317.1 - 3e-28 98.9 13.0 4.5e-28 98.3 13.0 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAX11317.1 - 1.8e-05 24.9 11.3 1.8e-05 24.9 11.3 2.3 2 1 0 2 2 2 2 EamA-like transporter family DUF4235 PF14019.6 GAX11317.1 - 0.031 14.3 0.0 14 5.9 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) PT PF04886.12 GAX11318.1 - 0.0044 16.5 19.9 0.0044 16.5 19.9 18.9 8 5 5 13 13 13 6 PT repeat Mito_carr PF00153.27 GAX11319.1 - 2.2e-42 142.9 1.2 5.6e-19 67.9 0.0 3.3 1 1 2 3 3 3 3 Mitochondrial carrier protein Trp_oprn_chp PF09534.10 GAX11319.1 - 0.038 13.8 2.2 3.8 7.3 0.2 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MAGI_u1 PF16663.5 GAX11320.1 - 1.8 8.7 6.3 0.18 11.9 0.7 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI HSP90 PF00183.18 GAX11321.1 - 8.8e-177 589.1 17.2 1.6e-176 588.2 17.2 1.4 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 GAX11321.1 - 4.3e-11 42.8 0.1 1.1e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAX11321.1 - 5.2e-10 39.8 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Secretin_N PF03958.17 GAX11321.1 - 0.0098 16.3 0.0 0.045 14.2 0.0 2.1 1 0 0 1 1 1 1 Bacterial type II/III secretion system short domain CRM1_C PF08767.11 GAX11324.1 - 1.6e-118 395.5 3.5 2.4e-117 391.7 0.7 2.4 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 GAX11324.1 - 7.5e-37 126.7 2.2 4.2e-36 124.3 2.2 2.4 1 0 0 1 1 1 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAX11324.1 - 1.3e-30 104.8 0.3 3.2e-30 103.6 0.3 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GAX11324.1 - 4.8e-30 103.4 1.2 4.8e-30 103.4 1.2 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 GAX11324.1 - 2.3e-15 55.8 0.2 6e-15 54.5 0.2 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 GAX11324.1 - 1.2e-12 47.5 0.6 4.2e-12 45.8 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Symplekin_C PF12295.8 GAX11324.1 - 0.046 13.8 0.9 2.5 8.2 0.0 3.5 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal DUF3385 PF11865.8 GAX11324.1 - 0.051 13.5 0.1 0.84 9.5 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) BID PF06393.11 GAX11324.1 - 0.089 12.3 0.8 4.3 6.8 0.0 3.2 3 0 0 3 3 3 0 BH3 interacting domain (BID) GDP_Man_Dehyd PF16363.5 GAX11325.1 - 8.3e-57 193.1 0.0 1.6e-56 192.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX11325.1 - 1.2e-47 162.4 0.0 1.8e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX11325.1 - 2.4e-11 43.2 0.0 3.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX11325.1 - 2.5e-10 40.0 0.0 1.8e-05 24.0 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 GAX11325.1 - 2.7e-08 33.3 0.1 7.3e-07 28.6 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX11325.1 - 7.5e-07 28.5 0.0 1.9e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAX11325.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GAX11325.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding A2L_zn_ribbon PF08792.10 GAX11326.1 - 0.16 11.7 3.6 0.33 10.7 3.6 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain Vps36-NZF-N PF16988.5 GAX11326.1 - 1 8.8 6.4 3.6 7.0 6.4 2.0 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Phytochelatin PF05023.14 GAX11327.1 - 3.3e-32 111.4 2.3 1.7e-31 109.1 0.0 2.8 2 1 1 3 3 3 1 Phytochelatin synthase Zip PF02535.22 GAX11327.1 - 0.24 10.6 3.6 0.37 10.0 3.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ATP-synt_B PF00430.18 GAX11327.1 - 0.36 10.9 3.0 0.77 9.8 3.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CRS1_YhbY PF01985.21 GAX11328.1 - 0.014 15.5 0.0 0.096 12.9 0.0 2.0 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain Arf PF00025.21 GAX11329.1 - 3.4e-11 42.9 0.0 1.4e-06 27.9 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 GAX11329.1 - 3.7e-08 33.6 0.7 0.0049 17.1 0.0 2.6 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAX11329.1 - 4.3e-07 29.4 0.3 0.015 14.5 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 GAX11329.1 - 2.8e-06 27.8 0.4 7.1e-06 26.5 0.1 1.9 2 1 0 2 2 1 1 AAA ATPase domain Ras PF00071.22 GAX11329.1 - 0.00017 21.3 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 2 Ras family AAA_33 PF13671.6 GAX11329.1 - 0.00065 19.9 0.1 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAX11329.1 - 0.002 18.2 0.0 0.28 11.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 GAX11329.1 - 0.0071 16.6 1.8 0.01 16.1 0.0 2.2 4 0 0 4 4 2 1 AAA domain Zeta_toxin PF06414.12 GAX11329.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 GAX11329.1 - 0.017 14.6 0.1 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region PAP_PilO PF06864.12 GAX11329.1 - 0.023 13.5 1.8 0.035 12.9 1.8 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) AAA_14 PF13173.6 GAX11329.1 - 0.036 14.1 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX11329.1 - 0.042 14.4 0.9 0.14 12.7 0.9 2.0 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAX11329.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 GAX11329.1 - 0.067 12.5 2.8 0.069 12.4 0.4 2.2 2 1 1 3 3 3 0 Septin MobB PF03205.14 GAX11329.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 GAX11329.1 - 0.098 12.4 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 GAX11329.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain RsgA_GTPase PF03193.16 GAX11329.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Gtr1_RagA PF04670.12 GAX11329.1 - 0.17 11.2 0.0 8.2 5.7 0.0 2.6 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Androgen_recep PF02166.16 GAX11329.1 - 1.1 8.0 8.8 2.3 7.0 8.8 1.4 1 0 0 1 1 1 0 Androgen receptor Dynamin_N PF00350.23 GAX11329.1 - 1.7 8.7 5.3 3.6 7.6 0.1 3.2 2 1 0 2 2 2 0 Dynamin family DIL PF01843.19 GAX11330.1 - 0.23 11.8 1.4 0.54 10.6 0.1 2.3 2 0 0 2 2 2 0 DIL domain HWE_HK PF07536.14 GAX11330.1 - 9.6 7.0 7.4 21 5.9 0.8 3.1 2 1 1 3 3 3 0 HWE histidine kinase Glyco_hydro_125 PF06824.11 GAX11331.1 - 1.9e-118 396.0 0.0 2.5e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) UPF0020 PF01170.18 GAX11332.1 - 2.7e-31 108.8 0.0 4.1e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 GAX11332.1 - 0.00081 19.2 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain N6_N4_Mtase PF01555.18 GAX11332.1 - 0.0089 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 GAX11332.1 - 0.19 11.4 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HSF_DNA-bind PF00447.17 GAX11334.1 - 1.2e-21 77.1 0.3 3.2e-21 75.8 0.1 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Mpv17_PMP22 PF04117.12 GAX11335.1 - 2.2e-13 50.2 0.9 3.8e-13 49.4 0.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2518 PF10726.9 GAX11338.1 - 0.12 12.1 0.6 0.33 10.6 0.6 1.7 1 0 0 1 1 1 0 Protein of function (DUF2518) Peptidase_U4 PF03419.13 GAX11338.1 - 0.15 11.3 7.3 0.24 10.7 0.7 2.2 2 0 0 2 2 2 0 Sporulation factor SpoIIGA TssN PF17555.2 GAX11338.1 - 0.45 9.9 6.4 2.1 7.6 1.7 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN MASE3 PF17159.4 GAX11338.1 - 0.48 10.0 16.0 0.017 14.7 4.4 2.5 1 1 1 2 2 2 0 Membrane-associated sensor domain CobS PF02654.15 GAX11338.1 - 0.81 9.8 0.1 0.81 9.8 0.1 3.4 2 1 0 2 2 2 0 Cobalamin-5-phosphate synthase Trp_oprn_chp PF09534.10 GAX11338.1 - 5.3 6.8 9.3 31 4.3 8.0 2.7 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2518 PF10726.9 GAX11339.1 - 0.013 15.1 0.2 0.013 15.1 0.2 2.4 2 0 0 2 2 2 0 Protein of function (DUF2518) Peptidase_U4 PF03419.13 GAX11339.1 - 6.9 5.9 10.9 0.75 9.0 0.7 2.3 2 1 0 2 2 2 0 Sporulation factor SpoIIGA PPDK_N PF01326.19 GAX11340.1 - 0.0079 15.5 0.9 0.02 14.1 0.0 1.7 1 1 1 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain HEAT_2 PF13646.6 GAX11340.1 - 0.034 14.5 1.0 0.35 11.3 0.1 3.1 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 GAX11340.1 - 0.074 13.4 1.0 0.73 10.3 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat Snf7 PF03357.21 GAX11341.1 - 3.8e-29 101.5 12.8 4.6e-29 101.2 12.8 1.1 1 0 0 1 1 1 1 Snf7 EPOP PF15223.6 GAX11341.1 - 0.084 12.2 1.7 0.33 10.3 0.5 1.9 1 1 0 2 2 2 0 Elongin BC and Polycomb repressive complex 2-associated protein DivIC PF04977.15 GAX11341.1 - 6.9 6.5 8.7 0.94 9.3 3.1 2.3 2 0 0 2 2 2 0 Septum formation initiator zf-C2H2_9 PF16293.5 GAX11342.1 - 0.053 13.4 0.2 0.49 10.3 0.0 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF241 PF03087.14 GAX11342.1 - 0.13 12.1 1.4 0.54 10.0 0.0 2.4 3 0 0 3 3 3 0 Arabidopsis protein of unknown function RRM_1 PF00076.22 GAX11343.1 - 1.5e-07 31.1 0.0 3.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fer2 PF00111.27 GAX11343.1 - 0.032 14.2 0.2 0.13 12.2 0.2 2.1 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ctr PF04145.15 GAX11344.1 - 4.9e-15 56.4 11.0 1.6e-12 48.3 11.0 2.2 1 1 0 1 1 1 1 Ctr copper transporter family RNA_pol_Rpc4 PF05132.14 GAX11345.1 - 0.014 15.8 0.9 0.019 15.4 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 GAX11345.1 - 0.018 13.8 1.4 0.02 13.7 1.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GAX11345.1 - 0.42 9.3 5.5 0.58 8.9 5.5 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GAX11345.1 - 0.67 9.7 10.9 0.83 9.4 10.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.6 GAX11345.1 - 3.9 7.4 10.6 5.3 6.9 10.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF913 PF06025.12 GAX11345.1 - 6 5.7 5.5 7.9 5.3 5.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EBP PF05241.12 GAX11347.1 - 1.9e-30 105.6 6.8 2.8e-30 105.1 6.8 1.2 1 0 0 1 1 1 1 Emopamil binding protein Aminotran_5 PF00266.19 GAX11348.1 - 6.1e-22 78.1 0.0 4.7e-20 71.9 0.0 2.4 2 1 0 2 2 2 1 Aminotransferase class-V MOSC_N PF03476.16 GAX11348.1 - 1.8e-20 73.0 0.0 4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 GAX11348.1 - 2.6e-17 63.1 0.0 4.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain CBM_14 PF01607.24 GAX11349.1 - 3.6e-06 27.0 5.7 3.6e-06 27.0 5.7 2.9 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Solute_trans_a PF03619.16 GAX11350.1 - 1.9e-71 240.7 12.9 3.2e-71 240.0 12.9 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4381 PF14316.6 GAX11350.1 - 0.061 13.6 3.6 0.33 11.2 1.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) PI-PLC-X PF00388.19 GAX11351.1 - 0.0047 16.5 0.0 0.049 13.2 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glyco_trans_1_4 PF13692.6 GAX11352.1 - 6.1e-08 33.2 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX11352.1 - 1.2e-06 28.2 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1906 PF08924.11 GAX11352.1 - 0.14 12.3 0.1 0.79 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) Guanylate_kin PF00625.21 GAX11353.1 - 4.7e-57 192.6 0.0 5.4e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 GAX11353.1 - 0.0002 21.5 0.0 0.0019 18.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAX11353.1 - 0.00035 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Methyltransf_25 PF13649.6 GAX11353.1 - 0.001 19.8 0.0 0.076 13.7 0.0 3.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX11353.1 - 0.0015 19.2 0.0 0.051 14.2 0.0 2.8 1 1 1 2 2 2 1 Methyltransferase domain AAA_18 PF13238.6 GAX11353.1 - 0.002 18.7 0.1 0.0061 17.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX11353.1 - 0.005 17.2 0.0 0.0068 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 GAX11353.1 - 0.0053 16.3 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region SRP54 PF00448.22 GAX11353.1 - 0.0092 15.6 0.0 0.017 14.7 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 GAX11353.1 - 0.011 15.7 0.1 0.15 12.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAX11353.1 - 0.019 15.3 0.0 0.042 14.2 0.0 1.7 2 0 0 2 2 1 0 RNA helicase MMR_HSR1 PF01926.23 GAX11353.1 - 0.023 14.8 0.0 0.04 14.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_12 PF08242.12 GAX11353.1 - 0.028 15.1 0.0 0.13 13.0 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain AAA_17 PF13207.6 GAX11353.1 - 0.053 14.0 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX11353.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3853 PF12964.7 GAX11353.1 - 0.077 13.2 0.0 9.8 6.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3853) NTPase_1 PF03266.15 GAX11353.1 - 0.093 12.6 0.1 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 NTPase Roc PF08477.13 GAX11353.1 - 0.095 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 GAX11353.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAX11353.1 - 0.16 11.7 0.3 0.95 9.2 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 GAX11353.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PTS_IIB PF02302.17 GAX11353.1 - 0.17 12.6 0.3 5.9 7.7 0.1 2.9 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit RVT_2 PF07727.14 GAX11354.1 - 2.9e-18 66.4 0.0 1.9e-17 63.7 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX11354.1 - 0.001 19.1 3.1 0.0022 18.0 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF1654 PF07867.11 GAX11354.1 - 0.037 13.7 0.2 0.28 10.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Methyltransf_25 PF13649.6 GAX11357.1 - 3e-16 59.9 0.0 6.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX11357.1 - 1.5e-15 57.4 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX11357.1 - 2e-14 54.1 0.0 3.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX11357.1 - 3.5e-13 49.6 0.0 4.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX11357.1 - 9.8e-13 48.6 0.0 2.3e-12 47.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 GAX11357.1 - 4.4e-07 29.6 0.0 7.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX11357.1 - 2.4e-05 23.9 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 GAX11357.1 - 2.8e-05 23.9 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 GAX11357.1 - 2.9e-05 23.3 0.1 3.9e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pox_MCEL PF03291.16 GAX11357.1 - 4.4e-05 22.8 0.0 5.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme FtsJ PF01728.19 GAX11357.1 - 0.00015 22.0 0.1 0.00034 20.8 0.1 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAX11357.1 - 0.00024 20.5 0.0 0.00035 20.0 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 GAX11357.1 - 0.00027 20.4 0.0 0.0011 18.5 0.0 1.7 1 1 1 2 2 2 1 Tellurite resistance protein TehB DREV PF05219.12 GAX11357.1 - 0.0015 17.7 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase DUF3419 PF11899.8 GAX11357.1 - 0.003 16.8 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) DUF1188 PF06690.11 GAX11357.1 - 0.0097 15.5 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) Methyltransf_32 PF13679.6 GAX11357.1 - 0.013 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 GAX11357.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 GAX11357.1 - 0.039 13.6 0.1 0.049 13.3 0.1 1.3 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 GAX11357.1 - 0.067 13.1 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 GAX11357.1 - 0.076 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PRMT5 PF05185.16 GAX11357.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase MetW PF07021.12 GAX11357.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MethyltransfD12 PF02086.15 GAX11357.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF4790 PF16037.5 GAX11358.1 - 0.034 14.6 2.0 0.07 13.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) Glyco_transf_22 PF03901.17 GAX11359.1 - 4.8e-54 184.2 27.9 2.2e-53 182.0 27.9 2.0 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family TetR PF13972.6 GAX11359.1 - 0.057 13.1 0.6 0.11 12.3 0.6 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF4337 PF14235.6 GAX11359.1 - 0.17 12.0 0.0 0.72 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Ribosomal_S17e PF00833.18 GAX11360.1 - 6.5e-59 197.2 0.1 7.2e-59 197.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 bVLRF1 PF18826.1 GAX11361.1 - 2.6e-38 131.2 0.3 2.6e-38 131.2 0.3 2.2 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor VATC PF18716.1 GAX11361.1 - 1.4e-07 31.2 4.1 3.2e-07 30.1 4.1 1.6 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_2 PF12796.7 GAX11361.1 - 3.9e-07 30.6 0.0 1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX11361.1 - 8.8e-07 29.4 0.0 6.3e-06 26.6 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX11361.1 - 1e-06 28.9 0.3 0.00038 20.8 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 GAX11361.1 - 2.9e-06 27.2 0.1 0.07 13.7 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeat Nop53 PF07767.11 GAX11361.1 - 0.0072 15.8 23.7 0.011 15.1 11.3 2.3 2 0 0 2 2 2 2 Nop53 (60S ribosomal biogenesis) Ank_5 PF13857.6 GAX11361.1 - 0.031 14.6 0.2 2.3 8.7 0.1 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) YL1 PF05764.13 GAX11361.1 - 0.05 13.7 23.6 0.074 13.2 2.8 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Presenilin PF01080.17 GAX11361.1 - 1.5 7.5 10.0 1 8.0 3.2 2.2 2 0 0 2 2 2 0 Presenilin eIF3_subunit PF08597.10 GAX11361.1 - 3.6 7.4 29.7 0.98 9.3 5.4 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 GAX11361.1 - 4.3 5.5 17.2 1.5 7.0 2.5 2.2 2 0 0 2 2 2 0 CDC45-like protein CCDC53 PF10152.9 GAX11361.1 - 5.7 7.4 11.6 0.35 11.3 0.5 2.7 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex zf-FCS PF06467.14 GAX11361.1 - 8.2 6.5 9.3 3.3 7.7 6.2 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif adh_short PF00106.25 GAX11362.1 - 6.2e-15 55.2 0.0 3.4e-11 43.0 0.0 3.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX11362.1 - 1.7e-08 34.3 0.0 7.1e-06 25.7 0.0 2.9 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX11362.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 GAX11362.1 - 0.19 11.2 0.0 0.86 9.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_16 PF10294.9 GAX11363.1 - 3.5e-21 75.7 0.3 1.2e-20 73.9 0.1 1.9 2 1 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 GAX11363.1 - 4.4e-06 26.3 0.1 1e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 GAX11363.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX11363.1 - 0.0019 18.9 0.0 0.0052 17.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX11363.1 - 0.0096 15.7 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX11363.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein NNMT_PNMT_TEMT PF01234.17 GAX11363.1 - 0.042 13.0 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family TehB PF03848.14 GAX11363.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 GAX11363.1 - 0.068 13.9 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ECSIT PF06239.11 GAX11363.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway HGTP_anticodon PF03129.20 GAX11364.1 - 5.1e-22 77.8 0.6 9.6e-22 77.0 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAX11364.1 - 3.9e-11 43.2 0.0 1.5e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Auto_anti-p27 PF06677.12 GAX11365.1 - 1.8e-25 88.8 29.4 8.4e-14 51.5 3.7 5.3 5 0 0 5 5 5 3 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.14 GAX11365.1 - 0.0015 18.8 6.7 1.4 9.3 0.0 4.5 3 1 1 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Phlebovirus_NSM PF07246.11 GAX11365.1 - 0.01 15.2 4.8 0.021 14.2 4.8 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ICEA PF05315.11 GAX11365.1 - 0.43 10.0 3.9 0.44 10.0 0.6 2.1 2 0 0 2 2 2 0 ICEA Protein DZR PF12773.7 GAX11365.1 - 3.6 7.7 13.0 8.5 6.5 0.5 4.3 4 0 0 4 4 4 0 Double zinc ribbon zf_C2H2_6 PF18450.1 GAX11365.1 - 7.5 6.4 6.4 3.8 7.3 0.2 3.3 3 0 0 3 3 3 0 Zinc Finger domain Ribosomal_S11 PF00411.19 GAX11366.1 - 9.4e-47 158.0 0.3 1.2e-46 157.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 GAX11366.1 - 0.13 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme ACT_6 PF13740.6 GAX11367.1 - 5.7e-19 67.9 0.4 1.6e-14 53.6 0.1 2.4 2 1 0 2 2 2 2 ACT domain ACT PF01842.25 GAX11367.1 - 2e-09 37.0 0.0 2.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 GAX11367.1 - 1.3e-08 35.3 0.0 0.0067 17.0 0.0 2.2 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 GAX11367.1 - 0.0048 16.6 1.7 0.012 15.4 0.0 2.3 3 0 0 3 3 3 1 ACT domain Hist_deacetyl PF00850.19 GAX11368.1 - 3.6e-45 154.8 0.0 7.5e-45 153.7 0.0 1.6 1 1 0 1 1 1 1 Histone deacetylase domain Lipase_3 PF01764.25 GAX11369.1 - 1.9e-15 57.0 0.2 7.8e-15 55.0 0.0 2.1 3 0 0 3 3 3 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAX11369.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 GAX11369.1 - 0.0047 16.5 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) HD_4 PF13328.6 GAX11369.1 - 0.12 12.1 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 HD domain Chlorophyllase PF07224.11 GAX11369.1 - 0.16 11.0 0.1 0.51 9.3 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase YfcL PF08891.11 GAX11369.1 - 0.26 11.7 2.4 6 7.3 0.0 3.3 3 0 0 3 3 3 0 YfcL protein RXT2_N PF08595.11 GAX11369.1 - 0.85 9.6 7.2 0.58 10.2 2.7 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF1223 PF06764.11 GAX11369.1 - 3.2 7.7 5.7 2.9 7.9 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1223) Lipase_3 PF01764.25 GAX11370.1 - 5.1e-17 62.1 0.0 1.3e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAX11370.1 - 0.0027 17.0 0.0 0.0049 16.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 GAX11370.1 - 0.006 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 GAX11370.1 - 0.0077 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAX11370.1 - 0.034 14.8 0.0 0.15 12.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.8 GAX11370.1 - 0.039 13.5 0.0 0.096 12.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Endonuc_Holl PF10107.9 GAX11370.1 - 1.6 8.6 4.1 3 7.7 0.0 2.4 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Sec7 PF01369.20 GAX11371.1 - 6.8e-60 201.9 0.2 1.2e-59 201.1 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAX11371.1 - 4.6e-24 85.1 1.1 4.6e-24 85.1 1.1 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Caerin_1 PF07440.12 GAX11371.1 - 0.24 11.5 7.5 0.79 9.9 0.7 2.9 3 0 0 3 3 3 0 Caerin 1 protein PseudoU_synth_1 PF01416.20 GAX11372.1 - 2.3e-30 105.2 0.1 1.2e-23 83.6 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase CTP_transf_like PF01467.26 GAX11373.1 - 2.4e-05 24.5 0.0 0.00013 22.1 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 GAX11373.1 - 0.095 12.2 0.1 0.17 11.3 0.1 1.4 2 0 0 2 2 2 0 ATP-sulfurylase FAM209 PF15206.6 GAX11373.1 - 1.3 8.8 3.2 2.2 8.1 3.2 1.3 1 0 0 1 1 1 0 FAM209 family DUF389 PF04087.14 GAX11374.1 - 8.9e-41 139.3 2.9 8.9e-41 139.3 2.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF389) PIG-F PF06699.11 GAX11374.1 - 0.0012 19.1 0.2 0.002 18.3 0.2 1.4 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F PHO4 PF01384.20 GAX11374.1 - 0.011 14.8 6.4 0.038 13.0 2.2 2.3 1 1 1 2 2 2 0 Phosphate transporter family DUF2157 PF09925.9 GAX11374.1 - 0.014 15.2 1.1 0.043 13.6 1.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF389 PF04087.14 GAX11375.1 - 4.4e-40 137.0 2.6 4.4e-40 137.0 2.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF389) DUF2157 PF09925.9 GAX11375.1 - 0.00046 20.0 0.9 0.0013 18.5 0.9 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) PIG-F PF06699.11 GAX11375.1 - 0.028 14.6 0.2 0.049 13.8 0.2 1.4 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F PHO4 PF01384.20 GAX11375.1 - 0.029 13.4 3.8 0.043 12.9 1.3 1.9 1 1 1 2 2 2 0 Phosphate transporter family Cupin_4 PF08007.12 GAX11376.1 - 6.8e-51 173.6 0.7 6.8e-51 173.6 0.7 1.9 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 GAX11376.1 - 2.5e-09 37.2 2.0 4.7e-08 33.0 0.0 3.1 1 1 1 2 2 2 1 Cupin-like domain DUF3644 PF12358.8 GAX11376.1 - 0.21 12.1 1.0 0.58 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) DUF1178 PF06676.11 GAX11376.1 - 2.4 8.5 6.1 0.18 12.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) HSF_DNA-bind PF00447.17 GAX11377.1 - 6.2e-18 65.2 1.9 7.6e-18 64.9 0.1 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Mannitol_dh_C PF08125.13 GAX11378.1 - 4.1e-70 236.0 0.0 5.9e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 GAX11378.1 - 4.9e-36 124.2 0.0 8.5e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Ank_2 PF12796.7 GAX11379.1 - 1.3e-30 105.8 4.8 7.9e-16 58.4 0.4 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Methyltransf_16 PF10294.9 GAX11379.1 - 3.3e-28 98.6 0.0 5.6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ank_4 PF13637.6 GAX11379.1 - 5.6e-17 61.9 0.2 1.7e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX11379.1 - 7.2e-17 59.8 0.1 7.1e-06 26.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX11379.1 - 4.6e-16 58.4 0.9 8.6e-07 29.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX11379.1 - 1e-14 54.4 1.5 1.1e-06 28.7 0.0 3.8 2 1 2 4 4 3 2 Ankyrin repeats (many copies) Methyltransf_31 PF13847.6 GAX11379.1 - 4e-07 29.9 0.0 8.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX11379.1 - 9.4e-07 28.5 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX11379.1 - 1.1e-06 28.2 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX11379.1 - 1.1e-05 26.0 0.0 4.1e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 GAX11379.1 - 0.00016 21.0 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Met_10 PF02475.16 GAX11379.1 - 0.00036 20.3 0.0 0.00061 19.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 GAX11379.1 - 0.0093 16.6 0.1 0.051 14.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX11379.1 - 0.021 15.6 0.0 0.051 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX11379.1 - 0.052 13.2 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Fasciclin PF02469.22 GAX11380.1 - 6.4e-47 159.0 0.0 5.4e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain AP_endonuc_2 PF01261.24 GAX11382.1 - 0.00082 18.9 0.0 0.0061 16.0 0.0 2.1 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel CS PF04969.16 GAX11383.1 - 0.079 14.0 0.0 0.16 13.0 0.0 1.4 1 0 0 1 1 1 0 CS domain CDC37_N PF03234.14 GAX11383.1 - 0.66 10.9 7.9 1.8 9.5 7.9 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding LSM PF01423.22 GAX11384.1 - 2.5e-16 59.1 0.0 2.9e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain RCC1 PF00415.18 GAX11385.1 - 3.2e-37 126.9 8.6 2.4e-06 28.1 0.0 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX11385.1 - 7.7e-25 86.1 23.4 1.1e-06 28.2 0.9 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat TAXi_N PF14543.6 GAX11386.1 - 9e-13 48.8 1.9 4.8e-12 46.5 1.9 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX11386.1 - 9.8e-13 48.2 0.0 7.7e-06 25.5 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX11386.1 - 0.0011 18.7 0.4 0.064 13.0 0.1 2.8 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal PIN_6 PF17146.4 GAX11386.1 - 0.04 14.4 0.0 0.09 13.3 0.0 1.5 1 0 0 1 1 1 0 PIN domain of ribonuclease gag-asp_proteas PF13975.6 GAX11386.1 - 0.18 12.4 0.0 7.7 7.2 0.0 2.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Str_synth PF03088.16 GAX11387.1 - 7.5e-15 54.8 0.0 1.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 GAX11387.1 - 0.0027 17.4 0.0 0.44 10.1 0.0 2.4 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Ribosomal_60s PF00428.19 GAX11389.1 - 0.0086 16.6 1.0 0.022 15.3 1.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3807 PF12720.7 GAX11389.1 - 0.012 15.9 0.2 0.059 13.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) RHINO PF15319.6 GAX11389.1 - 0.09 12.8 6.7 0.017 15.2 2.5 2.0 2 1 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Nitroreductase PF00881.24 GAX11390.1 - 7.9e-12 45.5 0.1 7.9e-12 45.5 0.1 1.7 2 0 0 2 2 2 1 Nitroreductase family SprT-like PF10263.9 GAX11393.1 - 4.2e-25 87.8 0.1 1.6e-24 85.9 0.0 2.0 2 0 0 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 GAX11393.1 - 2.7e-08 33.6 3.3 5.5e-08 32.6 3.3 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain HMG_box_2 PF09011.10 GAX11393.1 - 0.019 15.5 0.3 0.068 13.8 0.3 2.0 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 GAX11393.1 - 0.031 14.7 0.1 0.094 13.1 0.1 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box SdpI PF13630.6 GAX11394.1 - 0.19 11.9 4.0 6.2 7.0 0.8 2.6 3 0 0 3 3 3 0 SdpI/YhfL protein family MARVEL PF01284.23 GAX11394.1 - 0.23 11.5 8.1 0.61 10.1 8.1 1.8 1 1 0 1 1 1 0 Membrane-associating domain COPI_assoc PF08507.10 GAX11395.1 - 0.069 13.2 0.9 0.75 9.8 1.0 2.2 2 0 0 2 2 2 0 COPI associated protein DUF2206 PF09971.9 GAX11395.1 - 0.093 11.5 0.2 0.15 10.8 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2207 PF09972.9 GAX11395.1 - 0.17 10.6 0.2 0.2 10.4 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amastin PF07344.11 GAX11395.1 - 1.7 8.5 6.2 0.34 10.7 0.9 2.3 1 1 1 3 3 3 0 Amastin surface glycoprotein SOBP PF15279.6 GAX11396.1 - 1.1 9.8 11.8 1.6 9.3 11.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein FAM220 PF15487.6 GAX11396.1 - 1.7 8.2 10.1 0.9 9.1 7.9 1.5 1 1 0 1 1 1 0 FAM220 family Aldo_ket_red PF00248.21 GAX11397.1 - 1.1e-34 120.0 0.0 6.6e-34 117.4 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Alpha_E3_glycop PF01563.16 GAX11397.1 - 0.19 11.8 0.2 0.48 10.5 0.2 1.7 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Transglut_core PF01841.19 GAX11399.1 - 2.5e-11 44.0 0.3 5.1e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily Ank_2 PF12796.7 GAX11400.1 - 8.3e-32 109.6 3.2 6.8e-09 36.2 0.1 3.9 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX11400.1 - 3.1e-28 97.5 1.0 2.3e-09 37.3 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX11400.1 - 1.7e-24 85.9 6.0 1.6e-07 31.7 0.1 6.2 5 2 2 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX11400.1 - 1.9e-20 70.7 3.0 4.2e-06 26.7 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAX11400.1 - 4.4e-16 58.5 5.5 0.00013 22.3 0.2 5.8 6 1 0 6 6 6 3 Ankyrin repeat Use1 PF09753.9 GAX11400.1 - 9.5e-06 25.5 7.1 1.9e-05 24.5 7.1 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 Fib_alpha PF08702.10 GAX11400.1 - 0.0017 18.5 7.5 0.0045 17.2 7.5 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Prominin PF05478.11 GAX11400.1 - 0.0076 14.3 2.2 0.011 13.8 2.2 1.1 1 0 0 1 1 1 1 Prominin Mce4_CUP1 PF11887.8 GAX11400.1 - 0.0091 15.5 0.3 0.02 14.4 0.3 1.5 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative TcpS PF17456.2 GAX11400.1 - 0.015 15.3 0.2 0.034 14.2 0.2 1.6 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S CHAD PF05235.14 GAX11400.1 - 0.026 14.5 1.6 0.073 13.0 1.0 1.9 1 1 0 1 1 1 0 CHAD domain TPR_10 PF13374.6 GAX11400.1 - 0.03 14.2 0.2 9 6.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4407 PF14362.6 GAX11400.1 - 0.056 12.8 0.2 0.13 11.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 GAX11400.1 - 0.062 12.6 0.8 0.11 11.8 0.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CdvA PF18822.1 GAX11400.1 - 0.12 12.2 3.9 0.24 11.2 3.9 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain LMBR1 PF04791.16 GAX11400.1 - 0.13 11.1 0.8 0.18 10.7 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Form-deh_trans PF09163.11 GAX11400.1 - 0.29 10.9 0.6 0.62 9.9 0.6 1.5 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane DUF1664 PF07889.12 GAX11400.1 - 0.34 11.0 6.2 0.96 9.5 6.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 GAX11400.1 - 0.36 11.5 3.1 0.74 10.5 0.8 2.6 2 0 0 2 2 2 0 Initiation control protein YabA COG5 PF10392.9 GAX11400.1 - 0.53 10.5 7.0 2.6 8.2 4.2 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 OmpH PF03938.14 GAX11400.1 - 0.58 10.5 11.5 3.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SKA1 PF07160.12 GAX11400.1 - 0.58 10.0 10.3 0.15 11.9 5.4 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4446 PF14584.6 GAX11400.1 - 8.3 6.4 7.3 2.7 8.0 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Sec5 PF15469.6 GAX11403.1 - 8.7e-16 58.3 0.1 3.4e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 GAX11403.1 - 0.00015 20.5 0.6 0.00038 19.3 0.6 1.6 1 0 0 1 1 1 1 Dor1-like family Zw10 PF06248.13 GAX11403.1 - 0.52 8.8 4.7 0.07 11.7 0.3 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 HAD_2 PF13419.6 GAX11404.1 - 3.3e-20 72.9 0.0 1e-19 71.3 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX11404.1 - 7.4e-12 46.0 0.0 1.1e-11 45.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX11404.1 - 3.2e-06 27.1 0.1 6.5e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 GAX11404.1 - 0.0003 20.6 0.0 0.00049 19.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAX11404.1 - 0.0091 16.4 0.1 0.041 14.3 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Myosin_head PF00063.21 GAX11405.1 - 5.9e-205 682.4 0.0 8.7e-183 609.2 0.0 2.6 3 0 0 3 3 3 2 Myosin head (motor domain) Ank_2 PF12796.7 GAX11405.1 - 1e-12 48.4 4.4 0.00027 21.5 0.1 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 GAX11405.1 - 3.2e-12 46.4 0.1 3.2e-11 43.1 0.1 2.4 1 1 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 GAX11405.1 - 8.4e-10 38.7 9.0 0.016 15.5 0.4 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX11405.1 - 2.6e-06 27.9 0.9 0.00032 21.2 0.0 4.6 4 2 1 5 5 5 2 Ankyrin repeats (many copies) IQ PF00612.27 GAX11405.1 - 7.3e-05 22.2 22.5 0.086 12.7 0.6 5.5 5 0 0 5 5 5 3 IQ calmodulin-binding motif ATPase PF06745.13 GAX11405.1 - 0.015 14.7 0.1 0.071 12.4 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 GAX11405.1 - 0.042 14.2 0.8 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Ank_3 PF13606.6 GAX11405.1 - 0.17 12.5 11.1 15 6.5 0.0 6.6 7 0 0 7 7 7 0 Ankyrin repeat AAA_22 PF13401.6 GAX11405.1 - 0.18 12.1 0.5 1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ank PF00023.30 GAX11405.1 - 0.3 11.6 2.3 28 5.4 0.1 4.3 3 1 0 3 3 3 0 Ankyrin repeat ALMT PF11744.8 GAX11405.1 - 0.6 8.9 4.2 1.8 7.3 4.2 1.7 1 0 0 1 1 1 0 Aluminium activated malate transporter ABC2_membrane PF01061.24 GAX11407.1 - 2.1e-40 138.4 15.8 2.1e-40 138.4 15.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAX11407.1 - 7.8e-20 71.8 0.0 1.3e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX11407.1 - 6.9e-13 48.4 8.7 1e-12 47.9 8.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAX11407.1 - 0.00019 21.4 0.1 0.00036 20.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GAX11407.1 - 0.0098 16.0 0.3 0.02 15.0 0.3 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 GAX11407.1 - 0.055 13.3 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAX11407.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX11407.1 - 0.088 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GAX11407.1 - 0.098 12.4 0.2 0.31 10.8 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 GAX11407.1 - 0.16 11.4 0.2 5.9 6.3 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 GAX11407.1 - 4.1 7.4 4.7 2.4 8.2 1.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain adh_short PF00106.25 GAX11408.1 - 5.2e-24 84.8 0.0 7.9e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX11408.1 - 3.6e-18 66.0 0.0 6.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CIA30 PF08547.12 GAX11408.1 - 1e-17 64.6 0.0 1.9e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) rve PF00665.26 GAX11408.1 - 1.9e-08 34.5 0.0 4.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 GAX11408.1 - 1.8e-07 31.1 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Oxidored_nitro PF00148.19 GAX11408.1 - 0.03 13.1 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AMP-binding PF00501.28 GAX11409.1 - 4.2e-82 276.0 0.0 6e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Aldo_ket_red PF00248.21 GAX11409.1 - 3.4e-37 128.2 0.0 2.6e-35 122.0 0.0 2.6 2 1 0 2 2 2 1 Aldo/keto reductase family AMP-binding_C PF13193.6 GAX11409.1 - 4.6e-23 82.0 0.2 9.3e-23 81.0 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAX11409.1 - 6.1e-21 74.1 0.3 2.2e-20 72.3 0.4 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Abhydrolase_5 PF12695.7 GAX11411.1 - 1.3e-18 67.3 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX11411.1 - 0.00015 21.1 2.1 0.99 8.6 0.0 3.2 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX11411.1 - 1.5 9.4 4.9 0.87 10.1 0.5 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family zf-UBR PF02207.20 GAX11413.1 - 5.6e-18 64.9 13.6 2.1e-17 63.0 13.6 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ABC_tran PF00005.27 GAX11414.1 - 1.3e-45 155.2 0.0 2.6e-27 96.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAX11414.1 - 5.4e-40 137.8 33.6 5.8e-25 88.5 16.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAX11414.1 - 2e-11 43.8 5.3 0.00058 19.4 0.1 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX11414.1 - 8e-08 32.4 0.0 0.095 12.5 0.0 4.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAX11414.1 - 5.5e-05 23.2 0.1 0.025 14.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX11414.1 - 0.0002 21.1 0.4 0.62 9.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAX11414.1 - 0.00029 21.3 0.0 0.82 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAX11414.1 - 0.0043 17.0 0.1 0.66 9.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GAX11414.1 - 0.0061 16.6 1.2 3.2 7.8 0.1 2.7 2 0 0 2 2 2 2 Dynamin family SbcCD_C PF13558.6 GAX11414.1 - 0.017 15.3 0.0 6 7.2 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAX11414.1 - 0.032 14.8 0.1 1.9 9.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAX11414.1 - 0.058 13.1 0.4 4.4 7.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 GAX11414.1 - 0.067 12.5 0.1 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 GAX11414.1 - 0.097 12.2 0.1 15 5.1 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_25 PF13481.6 GAX11414.1 - 0.11 12.1 0.1 16 5.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 GAX11414.1 - 0.16 12.2 0.1 9.4 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 GAX11414.1 - 0.33 9.7 2.1 0.9 8.3 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Beta_helix PF13229.6 GAX11415.1 - 0.049 13.5 14.9 0.05 13.5 2.5 2.8 3 0 0 3 3 3 0 Right handed beta helix region EcoR124_C PF12008.8 GAX11415.1 - 0.18 11.5 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Mito_carr PF00153.27 GAX11416.1 - 2.5e-59 197.2 0.0 2.8e-20 72.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_8 PF13833.6 GAX11416.1 - 7.5e-11 41.7 0.1 2.3e-07 30.5 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX11416.1 - 3.2e-08 32.6 0.0 0.00097 18.5 0.1 4.8 4 0 0 4 4 4 2 EF hand cNMP_binding PF00027.29 GAX11416.1 - 1.3e-06 28.3 0.0 4.4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain EF-hand_7 PF13499.6 GAX11416.1 - 2.2e-06 28.0 2.0 0.0036 17.7 0.0 4.2 2 1 2 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX11416.1 - 1.8e-05 24.3 4.6 0.015 15.2 0.0 4.9 5 0 0 5 5 5 1 EF-hand domain EF-hand_5 PF13202.6 GAX11416.1 - 0.0095 15.4 3.0 0.055 13.0 0.1 3.6 4 0 0 4 4 4 1 EF hand AAA_18 PF13238.6 GAX11418.1 - 1.9e-05 25.2 0.0 5.6e-05 23.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain PRK PF00485.18 GAX11418.1 - 0.00076 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 GAX11418.1 - 0.0023 18.2 2.5 0.008 16.4 0.2 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX11418.1 - 0.0026 17.1 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin2 PF13189.6 GAX11418.1 - 0.008 16.3 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 Cytidylate kinase-like family DnaB_C PF03796.15 GAX11418.1 - 0.0084 15.5 0.0 0.02 14.2 0.0 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAX11418.1 - 0.0085 16.4 0.1 0.028 14.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 GAX11418.1 - 0.0099 15.1 0.2 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain T2SSE PF00437.20 GAX11418.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 GAX11418.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX11418.1 - 0.015 15.7 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 GAX11418.1 - 0.023 15.1 0.1 0.084 13.3 0.1 1.9 2 0 0 2 2 1 0 AAA domain Cytidylate_kin PF02224.18 GAX11418.1 - 0.027 14.2 1.1 0.059 13.1 0.1 2.0 3 0 0 3 3 2 0 Cytidylate kinase AAA_24 PF13479.6 GAX11418.1 - 0.048 13.4 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 GAX11418.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 GAX11418.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 GAX11418.1 - 0.086 12.6 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 GAX11418.1 - 0.088 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX11418.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 GAX11418.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 GAX11418.1 - 0.14 12.0 0.2 1.4 8.8 0.0 2.2 1 1 1 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.6 GAX11418.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX11418.1 - 0.15 12.5 0.1 0.45 11.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 GAX11418.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 NTPase SMC_N PF02463.19 GAX11420.1 - 3.4e-63 213.0 2.8 8e-63 211.8 2.8 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAX11420.1 - 1.6e-23 83.2 0.0 7.8e-23 81.0 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAX11420.1 - 2.4e-15 57.1 1.4 6e-07 29.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAX11420.1 - 2.7e-10 40.5 9.7 2.7e-10 40.5 9.7 4.4 2 2 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 GAX11420.1 - 3.6e-06 26.6 0.0 8.9e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 GAX11420.1 - 0.0088 16.6 12.2 0.0088 16.6 12.2 8.0 2 2 3 6 6 6 1 Apg6 coiled-coil region AAA_23 PF13476.6 GAX11420.1 - 0.69 10.4 116.5 0.018 15.6 54.9 6.8 2 2 1 3 3 3 0 AAA domain DUF525 PF04379.14 GAX11421.1 - 8.4e-50 167.0 0.0 2.4e-25 88.6 0.0 2.5 2 0 0 2 2 2 2 ApaG domain CENP-B_dimeris PF09026.10 GAX11421.1 - 0.0042 17.5 32.4 0.08 13.3 7.6 3.8 3 0 0 3 3 3 3 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GAX11421.1 - 0.083 12.6 40.7 0.06 13.1 15.3 3.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF4354 PF14263.6 GAX11421.1 - 0.13 12.1 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) LCD1 PF09798.9 GAX11421.1 - 0.24 9.9 2.5 0.34 9.4 2.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein NTPase_I-T PF01931.18 GAX11424.1 - 4e-43 147.0 0.0 4e-41 140.5 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function DUF84 HA PF03457.14 GAX11425.1 - 4.3e-40 135.9 4.9 4.2e-21 75.0 0.4 3.1 3 0 0 3 3 3 2 Helicase associated domain Codanin-1_C PF15296.6 GAX11425.1 - 0.12 12.5 0.4 0.12 12.5 0.4 2.3 2 0 0 2 2 2 0 Codanin-1 C-terminus Sec63 PF02889.16 GAX11427.1 - 0.00049 19.4 0.1 0.34 10.0 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain GTP_EFTU PF00009.27 GAX11428.1 - 5.3e-52 176.2 0.0 8.1e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX11428.1 - 3.1e-20 72.0 0.0 6.3e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX11428.1 - 1.3e-09 38.3 0.2 4.8e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX11428.1 - 2.6e-06 27.5 0.1 6.5e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 GAX11428.1 - 0.0049 16.9 0.2 0.015 15.3 0.1 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II Septin PF00735.18 GAX11428.1 - 0.019 14.2 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Septin Arf PF00025.21 GAX11428.1 - 0.02 14.3 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF681 PF05080.12 GAX11428.1 - 0.091 13.4 0.0 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF681) tRNA-synt_2b PF00587.25 GAX11429.1 - 9.8e-30 103.8 0.0 1.4e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAX11429.1 - 2.1e-16 60.1 1.9 4.3e-16 59.1 1.9 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain WHEP-TRS PF00458.20 GAX11429.1 - 0.03 14.5 1.0 0.068 13.3 1.0 1.6 1 0 0 1 1 1 0 WHEP-TRS domain BicD PF09730.9 GAX11429.1 - 0.052 12.0 2.6 0.08 11.4 2.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF3584 PF12128.8 GAX11429.1 - 0.057 11.0 0.4 0.09 10.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Snapin_Pallidin PF14712.6 GAX11429.1 - 0.079 13.4 1.3 0.16 12.4 1.3 1.5 1 0 0 1 1 1 0 Snapin/Pallidin RIFIN PF02009.16 GAX11429.1 - 0.39 10.6 4.6 0.7 9.7 4.6 1.3 1 0 0 1 1 1 0 Rifin Mon2_C PF16206.5 GAX11430.1 - 5.1e-12 44.8 3.1 2.3e-09 36.0 1.1 2.3 1 1 1 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 GAX11430.1 - 1.8e-07 31.0 4.5 4.2e-07 29.8 0.0 3.8 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 GAX11430.1 - 0.00093 19.0 3.8 0.89 9.5 0.0 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) bZIP_2 PF07716.15 GAX11430.1 - 0.71 10.0 4.9 1.7 8.8 0.9 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DUF1639 PF07797.14 GAX11431.1 - 0.0062 16.5 0.9 0.025 14.6 0.9 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1639) Flavi_NS2B PF01002.19 GAX11431.1 - 0.25 11.2 1.6 0.58 10.0 1.6 1.5 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B LRR_8 PF13855.6 GAX11432.1 - 8.9e-10 38.2 4.1 4.7e-05 23.1 0.8 3.4 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAX11432.1 - 1.1e-08 35.3 8.1 0.021 15.3 0.1 4.6 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX11432.1 - 0.062 13.9 4.9 15 6.6 0.3 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GAX11432.1 - 0.15 12.2 0.2 31 4.9 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich repeat MFS_1 PF07690.16 GAX11434.1 - 5.3e-29 101.2 14.1 1e-25 90.4 9.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX11434.1 - 3.8e-08 32.6 6.2 0.0061 15.5 0.0 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 GAX11434.1 - 3.8e-05 22.7 4.4 0.0017 17.3 2.1 2.4 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 GAX11434.1 - 6.4e-05 21.5 1.7 0.00033 19.2 1.2 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector EamA PF00892.20 GAX11434.1 - 0.00033 20.8 17.1 3.6 7.8 2.7 4.6 5 0 0 5 5 4 4 EamA-like transporter family PUCC PF03209.15 GAX11434.1 - 0.00047 19.3 0.7 0.0011 18.0 0.6 1.7 1 1 0 1 1 1 1 PUCC protein BT1 PF03092.16 GAX11434.1 - 0.013 13.7 0.3 0.35 9.0 0.0 2.5 2 0 0 2 2 2 0 BT1 family OATP PF03137.20 GAX11434.1 - 0.039 12.2 0.1 0.078 11.3 0.1 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UPF0139 PF03669.13 GAX11434.1 - 0.072 13.0 1.4 0.44 10.4 0.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) DUF4227 PF14004.6 GAX11434.1 - 0.087 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF3611 PF12263.8 GAX11434.1 - 0.7 9.8 6.2 0.11 12.4 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) DUF1772 PF08592.11 GAX11434.1 - 3.3 8.0 5.6 1.9 8.8 0.2 3.1 4 1 0 4 4 3 0 Domain of unknown function (DUF1772) DUF1129 PF06570.11 GAX11434.1 - 5.1 6.5 9.4 1.9 8.0 0.2 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) Claudin_2 PF13903.6 GAX11434.1 - 7.2 6.3 12.1 5.5 6.7 0.6 4.1 1 1 3 5 5 5 0 PMP-22/EMP/MP20/Claudin tight junction Myb_DNA-binding PF00249.31 GAX11435.1 - 6.2e-35 119.1 1.6 1.4e-15 57.2 1.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX11435.1 - 9.3e-29 99.5 0.7 8.4e-10 38.8 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX11435.1 - 3e-05 23.8 2.2 0.00038 20.3 0.3 3.0 2 2 1 3 3 3 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 GAX11435.1 - 0.00034 20.9 1.7 0.073 13.4 0.4 2.7 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 GAX11435.1 - 0.13 12.4 0.3 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 GAX11435.1 - 1.1 9.7 10.1 2.2 8.7 0.8 3.5 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Aminotran_1_2 PF00155.21 GAX11436.1 - 1.2e-66 225.4 0.0 1.4e-66 225.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAX11436.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 GAX11436.1 - 0.013 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 GAX11436.1 - 0.014 14.3 0.0 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V PALP PF00291.25 GAX11437.1 - 2.4e-67 227.4 0.6 2.7e-67 227.3 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Anoctamin PF04547.12 GAX11438.1 - 8.4e-11 41.4 5.9 8.4e-11 41.4 5.9 2.2 2 2 0 2 2 2 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 GAX11438.1 - 1.5e-08 34.3 8.5 7.3e-07 28.8 8.4 2.4 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAX11438.1 - 0.2 11.9 0.0 1.1 9.5 0.0 2.0 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DRIM PF07539.12 GAX11440.1 - 2.7e-78 263.9 0.4 2.7e-78 263.9 0.4 4.2 4 0 0 4 4 4 2 Down-regulated in metastasis Importin_rep_3 PF18806.1 GAX11440.1 - 0.13 12.3 2.1 36 4.5 0.1 4.2 4 0 0 4 4 4 0 Importin 13 repeat MMS19_N PF14500.6 GAX11440.1 - 0.68 9.5 5.3 0.95 9.0 0.0 3.9 3 1 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Histone PF00125.24 GAX11441.1 - 3.3e-40 137.5 0.2 3.4e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAX11441.1 - 0.024 15.0 0.0 0.036 14.4 0.0 1.2 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 GAX11441.1 - 0.074 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF2647 PF10839.8 GAX11441.1 - 0.23 11.5 0.9 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) SIR2 PF02146.17 GAX11442.1 - 2.2e-51 174.3 0.0 3.1e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family HD_3 PF13023.6 GAX11443.1 - 3.8e-36 124.5 0.1 2.8e-35 121.7 0.1 1.9 1 1 0 1 1 1 1 HD domain HD_2 PF12917.7 GAX11443.1 - 2.7e-05 24.0 0.1 6.7e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 GAX11443.1 - 0.028 14.6 0.0 0.06 13.6 0.0 1.6 1 1 0 1 1 1 0 HD domain Voltage_CLC PF00654.20 GAX11444.1 - 5.6e-58 196.9 25.1 1e-56 192.7 20.1 3.1 1 1 1 2 2 2 2 Voltage gated chloride channel GNVR PF13807.6 GAX11444.1 - 0.52 10.3 1.5 1.8 8.5 0.0 2.7 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Prp19 PF08606.11 GAX11445.1 - 2.1e-25 88.5 3.2 5.2e-25 87.2 3.2 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 GAX11445.1 - 1e-06 28.9 3.1 0.029 14.7 0.1 5.1 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX11445.1 - 1.6e-06 27.7 0.1 4.3e-06 26.3 0.1 1.7 2 1 0 2 2 2 1 WD40-like domain WD40 PF00400.32 GAX11445.1 - 7.8e-06 26.5 5.9 0.053 14.4 0.1 5.1 4 1 0 4 4 4 1 WD domain, G-beta repeat U-box PF04564.15 GAX11445.1 - 0.00035 20.7 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain Utp8 PF10395.9 GAX11445.1 - 0.017 13.7 1.9 0.17 10.3 0.1 2.4 3 0 0 3 3 3 0 Utp8 family TSNAXIP1_N PF15739.5 GAX11445.1 - 0.019 15.3 1.0 0.019 15.3 1.0 2.2 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Frtz PF11768.8 GAX11445.1 - 0.024 13.0 0.4 0.48 8.7 0.2 2.6 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 GAX11445.1 - 0.042 12.9 0.4 1.1 8.2 0.2 2.5 1 1 0 2 2 2 0 Coatomer WD associated region YfcL PF08891.11 GAX11445.1 - 0.15 12.4 1.1 0.37 11.2 1.1 1.8 1 1 0 1 1 1 0 YfcL protein Rhomboid PF01694.22 GAX11446.1 - 1.6e-20 73.7 15.9 2.2e-20 73.2 15.9 1.2 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 GAX11446.1 - 0.0001 22.3 9.1 0.00015 21.8 9.1 1.2 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 GAX11446.1 - 0.033 14.7 1.8 0.085 13.4 1.8 1.7 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) DUF2417 PF10329.9 GAX11446.1 - 6.7 6.1 10.2 8.1 5.8 9.6 1.4 1 1 0 1 1 1 0 Region of unknown function (DUF2417) Myosin_head PF00063.21 GAX11447.1 - 2.2e-191 637.6 4.2 3.2e-110 369.4 0.0 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 GAX11447.1 - 0.00083 19.6 0.0 0.0033 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 GAX11447.1 - 0.0011 18.0 0.2 0.0023 16.9 0.2 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.6 GAX11447.1 - 0.0041 17.5 0.1 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 GAX11447.1 - 0.027 14.2 0.1 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 GAX11447.1 - 0.028 13.5 0.1 0.086 11.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 GAX11447.1 - 0.086 12.4 0.1 0.48 9.9 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 GAX11447.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAX11447.1 - 0.15 12.4 0.2 0.72 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 GAX11447.1 - 0.91 10.0 3.0 2.1 8.9 0.4 2.7 2 1 0 2 2 2 0 ABC transporter SOBP PF15279.6 GAX11448.1 - 0.022 15.4 1.7 0.022 15.4 1.7 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein TALPID3 PF15324.6 GAX11448.1 - 0.037 11.7 11.8 0.046 11.4 11.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Rav1p_C PF12234.8 GAX11449.1 - 9e-31 107.0 2.0 1.5e-30 106.3 2.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal SH2 PF00017.24 GAX11449.1 - 2.1e-05 24.5 0.0 0.0014 18.7 0.0 2.6 2 0 0 2 2 2 1 SH2 domain PDZ PF00595.24 GAX11449.1 - 0.00049 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX11449.1 - 0.0031 17.3 0.0 0.0098 15.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Adenylsucc_synt PF00709.21 GAX11450.1 - 9.6e-169 561.7 0.0 1.1e-168 561.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase G6PD_N PF00479.22 GAX11450.1 - 0.17 12.5 0.0 0.28 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Chloroa_b-bind PF00504.21 GAX11451.1 - 6e-40 137.4 0.4 8.2e-40 137.0 0.4 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Ribosomal_S3_C PF00189.20 GAX11452.1 - 1.1e-19 70.7 3.0 3.4e-19 69.1 3.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAX11452.1 - 1.6e-09 37.5 0.0 3.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 KH domain nec1 PF10379.9 GAX11452.1 - 0.16 11.4 0.1 2.5 7.5 0.1 2.1 1 1 1 2 2 2 0 Virulence protein nec1 CP12 PF02672.15 GAX11453.1 - 2.7e-07 31.2 13.0 0.00029 21.5 0.4 3.6 1 1 2 3 3 3 2 CP12 domain SOAR PF16533.5 GAX11453.1 - 0.019 14.9 1.2 0.86 9.6 0.0 2.6 2 1 1 3 3 3 0 STIM1 Orai1-activating region Phage_ABA_S PF18066.1 GAX11453.1 - 0.079 13.7 2.4 0.29 11.8 0.5 2.3 2 1 0 2 2 2 0 Phage ABA sandwich domain DUF3502 PF12010.8 GAX11453.1 - 0.22 12.2 1.8 0.43 11.2 1.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3502) Myb_DNA-binding PF00249.31 GAX11455.1 - 1e-13 51.2 0.4 2.6e-13 49.9 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX11455.1 - 4.5e-05 23.6 0.5 0.00016 21.8 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX11455.1 - 0.00011 22.0 0.7 0.0007 19.4 0.1 2.4 2 0 0 2 2 2 1 Myb DNA-binding like Fmp27 PF10344.9 GAX11455.1 - 0.049 11.7 0.1 0.074 11.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 MFS_1 PF07690.16 GAX11457.1 - 7.3e-27 94.2 30.3 1.3e-26 93.4 30.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Pirin PF02678.16 GAX11458.1 - 0.065 13.2 0.2 0.13 12.3 0.1 1.6 2 0 0 2 2 2 0 Pirin PAP_fibrillin PF04755.12 GAX11460.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.7 1 1 1 2 2 2 0 PAP_fibrillin 2-oxoacid_dh PF00198.23 GAX11461.1 - 3.1e-62 210.1 0.5 5.2e-62 209.3 0.1 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX11461.1 - 1.1e-18 66.8 0.1 2.8e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAX11461.1 - 2.2e-12 47.1 0.1 3.7e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAX11461.1 - 0.0038 17.0 0.4 0.2 11.5 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like GCV_H PF01597.19 GAX11461.1 - 0.0084 16.0 0.7 0.42 10.5 0.0 2.5 2 0 0 2 2 2 1 Glycine cleavage H-protein NAD_binding_2 PF03446.15 GAX11461.1 - 0.015 15.5 0.4 0.049 13.8 0.1 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase MtrB PF05440.12 GAX11461.1 - 0.06 13.8 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF4112 PF13430.6 GAX11461.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) HlyD_3 PF13437.6 GAX11461.1 - 0.14 12.9 0.1 2 9.2 0.0 2.6 2 1 1 3 3 3 0 HlyD family secretion protein Ribosomal_L36e PF01158.18 GAX11462.1 - 3.5e-22 78.5 0.8 3.9e-22 78.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Ribosomal_L34e PF01199.18 GAX11463.1 - 1.1e-33 115.4 5.6 1.3e-33 115.1 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Pkinase PF00069.25 GAX11464.1 - 9.4e-23 80.9 0.0 2.9e-22 79.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 GAX11464.1 - 8.1e-22 78.1 0.0 2.9e-21 76.3 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX11464.1 - 8.8e-07 29.0 0.0 0.017 15.0 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAX11464.1 - 2.6e-06 27.2 0.0 1.1e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PDZ_6 PF17820.1 GAX11464.1 - 0.00034 20.4 0.0 0.00093 19.0 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 GAX11464.1 - 0.0015 17.8 0.0 0.0053 16.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX11464.1 - 0.0017 18.3 0.3 0.0017 18.3 0.3 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX11464.1 - 0.0085 14.9 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase CCB1 PF12046.8 GAX11464.1 - 0.049 13.0 0.1 0.097 12.0 0.1 1.4 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B FTA2 PF13095.6 GAX11464.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Sulfate_transp PF00916.20 GAX11465.1 - 6.4e-34 117.3 8.3 1.1e-33 116.6 8.3 1.3 1 1 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 GAX11465.1 - 0.27 11.6 13.9 1.9 8.9 2.3 2.6 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily EF-hand_5 PF13202.6 GAX11467.1 - 0.049 13.1 0.2 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 GAX11467.1 - 0.058 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 GAX11467.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 GAX11467.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair Mito_carr PF00153.27 GAX11468.1 - 1.4e-53 178.7 2.2 5.3e-18 64.7 0.0 3.1 1 1 2 3 3 3 3 Mitochondrial carrier protein N2227 PF07942.12 GAX11469.1 - 3.7e-46 157.5 0.0 5.5e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 GAX11469.1 - 0.0093 16.7 0.0 0.069 13.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX11469.1 - 0.017 15.8 0.1 0.56 10.9 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAX11469.1 - 0.041 14.6 0.0 7.3 7.4 0.0 2.6 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAX11469.1 - 0.073 12.9 0.0 0.34 10.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PspB PF06667.12 GAX11469.1 - 0.13 12.3 0.2 0.31 11.1 0.2 1.6 1 0 0 1 1 1 0 Phage shock protein B Ank_2 PF12796.7 GAX11470.1 - 1.4e-38 131.3 1.6 1.2e-17 64.2 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX11470.1 - 8.8e-23 80.4 0.1 1.6e-11 44.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX11470.1 - 1.2e-18 66.9 1.1 5e-06 26.7 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX11470.1 - 1.7e-18 64.8 0.8 3.1e-05 24.0 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 GAX11470.1 - 2.4e-18 65.7 2.2 7.6e-06 26.1 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat ACTH_assoc PF16102.5 GAX11470.1 - 0.02 15.7 1.8 0.074 13.9 1.8 1.9 1 0 0 1 1 1 0 ACTH-associated domain Pec_lyase PF09492.10 GAX11470.1 - 0.095 12.0 0.9 0.17 11.2 0.9 1.3 1 0 0 1 1 1 0 Pectic acid lyase zf-TAZ PF02135.16 GAX11471.1 - 1.4e-34 118.3 67.1 7e-16 58.4 16.0 5.3 6 0 0 6 6 6 3 TAZ zinc finger HAT_KAT11 PF08214.11 GAX11471.1 - 2.3e-31 109.3 0.0 4.9e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 GAX11471.1 - 2e-19 69.4 0.0 1.1e-18 67.0 0.0 2.4 3 0 0 3 3 3 1 Bromodomain PHD PF00628.29 GAX11471.1 - 4.9e-07 29.5 7.8 4.9e-07 29.5 7.8 3.8 4 0 0 4 4 4 1 PHD-finger ZZ PF00569.17 GAX11471.1 - 3.2e-06 26.8 7.4 3.2e-06 26.8 7.4 4.3 5 1 0 5 5 5 1 Zinc finger, ZZ type KIX_2 PF16987.5 GAX11471.1 - 9.6e-05 22.3 1.9 0.00031 20.7 0.0 2.7 2 0 0 2 2 2 1 KIX domain HlyIII PF03006.20 GAX11472.1 - 9.1e-33 113.9 17.0 1.4e-32 113.2 17.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related LRR_6 PF13516.6 GAX11472.1 - 1.6e-05 24.6 0.0 3.7 7.9 0.0 3.9 3 0 0 3 3 3 3 Leucine Rich repeat WW PF00397.26 GAX11473.1 - 2.2e-06 27.7 0.0 5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 WW domain zf-U1 PF06220.12 GAX11473.1 - 2.3e-06 27.2 0.1 3.5e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 U1 zinc finger RNase_PH PF01138.21 GAX11475.1 - 9.7e-21 74.6 0.4 1.9e-20 73.7 0.4 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX11475.1 - 6.7e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 FPN1 PF06963.12 GAX11477.1 - 1.7e-70 237.8 7.0 2e-70 237.6 7.0 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) VDE PF07137.11 GAX11478.1 - 1.5e-80 270.1 2.0 1.9e-80 269.8 2.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Lipocalin PF00061.23 GAX11478.1 - 1.2e-05 25.5 0.1 2e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 GAX11478.1 - 0.0042 17.0 0.1 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Lipocalin-like domain FAD_binding_3 PF01494.19 GAX11479.1 - 5.6e-17 62.0 0.6 2.8e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 GAX11479.1 - 8.5e-05 21.8 3.2 0.00022 20.4 3.2 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAX11479.1 - 0.00022 21.4 1.8 0.00047 20.3 0.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX11479.1 - 0.00032 20.0 0.4 0.0016 17.8 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX11479.1 - 0.0014 18.0 0.4 0.0026 17.1 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAX11479.1 - 0.0017 17.1 1.3 0.0026 16.5 1.3 1.3 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 GAX11479.1 - 0.0027 16.8 0.0 0.41 9.7 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.27 GAX11479.1 - 0.0029 18.1 0.1 0.0059 17.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX11479.1 - 0.018 14.7 1.5 0.018 14.7 1.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 GAX11479.1 - 0.058 12.5 1.1 0.086 11.9 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAX11479.1 - 0.13 11.1 0.5 0.94 8.3 0.7 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 GAX11479.1 - 0.16 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GAX11479.1 - 0.47 9.8 3.7 0.7 9.2 3.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPR_1 PF00515.28 GAX11480.1 - 1.1e-05 25.1 3.8 4.2e-05 23.2 0.4 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX11480.1 - 0.00013 21.8 4.8 0.0004 20.3 0.9 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX11480.1 - 0.00015 22.2 5.0 0.00015 22.2 5.0 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX11480.1 - 0.0002 21.0 3.4 0.005 16.5 1.1 2.6 1 1 1 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.6 GAX11480.1 - 0.00071 19.6 0.3 0.002 18.2 0.3 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 GAX11480.1 - 0.0012 19.5 4.9 0.002 18.8 2.7 2.7 3 0 0 3 3 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11480.1 - 0.0019 18.3 0.4 0.064 13.5 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX11480.1 - 0.0032 17.6 0.5 0.0032 17.6 0.5 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Tim54 PF11711.8 GAX11480.1 - 0.017 13.9 0.9 4.1 6.1 0.8 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TPR_17 PF13431.6 GAX11480.1 - 0.035 14.5 3.3 0.046 14.1 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX11480.1 - 0.071 13.2 0.1 0.071 13.2 0.1 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX11480.1 - 0.17 12.1 1.6 0.35 11.1 0.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAX11480.1 - 0.21 12.3 1.9 1.4 9.7 1.9 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Helicase_C PF00271.31 GAX11481.1 - 1.5e-24 86.5 0.3 5.3e-24 84.7 0.3 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX11481.1 - 1.3e-21 77.1 0.0 3.1e-21 75.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAX11481.1 - 1.2e-06 27.9 0.6 2.1e-06 27.1 0.6 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAX11481.1 - 0.00013 22.1 0.0 0.00039 20.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GATase_4 PF13230.6 GAX11482.1 - 2.7e-83 279.0 0.0 3.9e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAX11482.1 - 0.00035 20.8 0.0 0.00063 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GPDPase_memb PF10110.9 GAX11484.1 - 2e-07 30.1 28.2 1.5e-05 24.0 28.2 2.5 1 1 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Rab5ip PF07019.12 GAX11485.1 - 0.14 12.7 0.2 0.14 12.7 0.2 3.6 2 1 2 4 4 4 0 Rab5-interacting protein (Rab5ip) Smg4_UPF3 PF03467.15 GAX11486.1 - 0.96 9.4 14.4 0.053 13.5 7.7 2.3 2 1 0 2 2 2 0 Smg-4/UPF3 family TRAM_LAG1_CLN8 PF03798.16 GAX11487.1 - 3e-09 36.9 18.3 3.2e-09 36.8 17.7 1.4 1 1 0 1 1 1 1 TLC domain AGTRAP PF06396.11 GAX11487.1 - 0.049 13.4 0.2 0.088 12.6 0.2 1.4 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) 2TM PF13239.6 GAX11487.1 - 0.54 10.6 5.5 1.7 9.0 5.5 1.8 1 0 0 1 1 1 0 2TM domain ATP-synt_I PF03899.15 GAX11487.1 - 9.6 6.6 11.4 0.37 11.2 2.4 2.9 2 1 1 3 3 3 0 ATP synthase I chain GPDPase_memb PF10110.9 GAX11489.1 - 0.00097 18.0 12.7 0.00097 18.0 12.7 2.7 1 1 1 3 3 3 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Myb_DNA-binding PF00249.31 GAX11490.1 - 6e-10 39.2 0.8 1.7e-09 37.7 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 GAX11490.1 - 3.8e-08 33.0 2.5 7e-08 32.2 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 GAX11490.1 - 9.9e-06 25.7 0.0 3.4e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 GAX11490.1 - 0.013 15.8 3.6 0.037 14.3 3.6 1.7 1 0 0 1 1 1 0 C1 domain Pro_isomerase PF00160.21 GAX11491.1 - 3.9e-47 160.4 0.0 9.4e-47 159.2 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HAD_2 PF13419.6 GAX11492.1 - 1.9e-21 76.9 0.0 2.8e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX11492.1 - 5.6e-13 49.7 0.0 1.2e-07 32.3 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX11492.1 - 0.0003 21.3 0.1 0.0014 19.1 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAX11492.1 - 0.0059 16.7 0.0 4.1 7.6 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX11492.1 - 0.0075 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like LSM14 PF12701.7 GAX11493.1 - 4.2e-28 97.3 0.0 7e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 GAX11493.1 - 1.4e-07 32.3 14.4 7.4e-05 23.6 0.2 3.3 2 1 1 3 3 3 2 FDF domain SM-ATX PF14438.6 GAX11493.1 - 7.5e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.11 GAX11493.1 - 2.2 9.0 23.7 0.59 10.9 19.1 2.1 2 0 0 2 2 2 0 Glycine rich protein family MSA-2c PF12238.8 GAX11493.1 - 4.3 7.3 11.0 8 6.4 11.0 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c UDG PF03167.19 GAX11494.1 - 1.8e-21 76.7 0.0 3.4e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Fapy_DNA_glyco PF01149.24 GAX11494.1 - 2.3e-13 50.8 0.0 6.8e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 GAX11494.1 - 1.1e-12 47.8 0.0 2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 GAX11494.1 - 0.057 12.2 0.0 0.095 11.4 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) RPE65 PF03055.15 GAX11495.1 - 7.7e-73 246.2 0.0 9.3e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein UBA_4 PF14555.6 GAX11495.1 - 0.11 12.4 0.1 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain FAM60A PF15396.6 GAX11497.1 - 0.053 13.5 5.1 0.087 12.8 5.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Nse5 PF08691.10 GAX11497.1 - 0.17 10.5 2.8 0.26 9.9 2.8 1.3 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 POLO_box PF00659.18 GAX11498.1 - 0.056 13.6 0.1 0.079 13.2 0.1 1.4 1 1 0 1 1 1 0 POLO box duplicated region Ribosomal_L23 PF00276.20 GAX11499.1 - 8.5e-11 42.1 1.3 3.7e-10 40.0 1.3 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 HALZ PF02183.18 GAX11499.1 - 0.11 12.7 0.6 0.18 12.1 0.1 1.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper UDPGP PF01704.18 GAX11500.1 - 1.8e-17 63.1 0.0 8.6e-17 60.9 0.0 1.8 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Lipase_3 PF01764.25 GAX11503.1 - 2.3e-08 34.0 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 GAX11503.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein SnoaL PF07366.12 GAX11504.1 - 0.15 11.8 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Sec1 PF00995.23 GAX11505.1 - 2.2e-86 291.4 0.0 2.7e-86 291.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family L27_1 PF09058.10 GAX11507.1 - 0.061 13.3 1.5 0.32 11.0 1.5 2.1 1 1 0 1 1 1 0 L27_1 YjbH PF06082.11 GAX11507.1 - 0.54 9.0 3.1 0.81 8.4 3.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH EXS PF03124.14 GAX11508.1 - 2.7e-67 227.5 7.6 3.2e-67 227.2 7.6 1.0 1 0 0 1 1 1 1 EXS family PRP1_N PF06424.12 GAX11509.1 - 2.3e-33 115.7 29.2 1.1e-21 77.7 5.3 4.9 4 1 1 5 5 5 3 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 GAX11509.1 - 2.3e-25 87.1 32.1 0.0015 19.2 0.7 13.2 7 4 6 13 13 13 9 Tetratricopeptide repeat TPR_19 PF14559.6 GAX11509.1 - 6.4e-16 58.6 17.3 7.9e-06 26.3 0.1 9.1 8 1 3 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAX11509.1 - 6.4e-08 33.1 12.0 0.2 12.3 1.8 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX11509.1 - 1.3e-07 31.2 17.6 1.3 9.3 0.0 9.2 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX11509.1 - 0.00034 20.8 2.0 13 6.4 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11509.1 - 0.00091 19.3 0.4 63 4.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Suf PF05843.14 GAX11509.1 - 0.0023 18.0 2.3 9.9 6.0 0.0 4.2 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) DUF3808 PF10300.9 GAX11509.1 - 0.0073 15.1 1.5 1.5 7.5 0.0 4.0 2 2 1 4 4 4 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 GAX11509.1 - 0.0076 16.4 0.4 13 6.1 0.0 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GAX11509.1 - 0.011 15.6 0.0 4.8 7.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4148 PF13663.6 GAX11509.1 - 0.031 14.5 1.3 0.095 12.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) TPR_11 PF13414.6 GAX11509.1 - 0.047 13.4 4.3 2.7 7.8 0.0 4.4 5 0 0 5 5 4 0 TPR repeat TPR_6 PF13174.6 GAX11509.1 - 0.062 14.0 6.9 1e+02 3.8 0.1 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX11509.1 - 2.2 8.7 11.1 22 5.4 0.6 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat Bromodomain PF00439.25 GAX11510.1 - 2.8e-07 30.5 0.0 6.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 GAX11510.1 - 8.6e-05 22.4 0.4 0.00019 21.2 0.4 1.6 1 0 0 1 1 1 1 PHD-finger FYRN PF05964.14 GAX11510.1 - 0.0004 20.2 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Tudor-knot PF11717.8 GAX11510.1 - 0.013 15.4 0.1 0.033 14.1 0.1 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain RF-1 PF00472.20 GAX11511.1 - 0.053 13.5 0.1 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 RF-1 domain HEAT_EZ PF13513.6 GAX11513.1 - 0.0017 18.8 6.5 0.74 10.4 0.0 5.3 5 1 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 GAX11513.1 - 0.0067 16.8 2.3 0.31 11.5 0.1 3.4 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.23 GAX11513.1 - 0.0086 16.1 10.6 0.23 11.5 0.0 6.2 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DUF383 PF04063.14 GAX11513.1 - 0.017 14.8 0.5 0.12 12.0 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF383) Proteasom_PSMB PF10508.9 GAX11513.1 - 0.037 12.5 0.2 0.12 10.8 0.1 1.9 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT PF02985.22 GAX11513.1 - 0.36 11.2 6.1 3.1 8.3 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat DnaJ PF00226.31 GAX11514.1 - 5.8e-13 48.8 0.0 8.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Glycos_transf_2 PF00535.26 GAX11515.1 - 8.2e-20 71.3 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX11515.1 - 0.0057 16.6 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 HemY_N PF07219.13 GAX11516.1 - 1 9.6 3.5 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 HemY protein N-terminus TMEM208_SND2 PF05620.11 GAX11516.1 - 5 6.9 9.9 0.9 9.3 0.2 3.1 3 1 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 FMO-like PF00743.19 GAX11517.1 - 7.9e-43 146.7 0.0 1.7e-34 119.2 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAX11517.1 - 4.4e-18 65.6 0.5 3.9e-09 36.2 0.0 3.9 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX11517.1 - 3.3e-08 33.7 0.1 2.2e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX11517.1 - 4.5e-08 32.7 0.0 8.2e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX11517.1 - 1.6e-06 28.2 0.2 4.7e-06 26.7 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 GAX11517.1 - 2.7e-06 27.2 1.4 0.00014 21.5 1.2 2.8 1 1 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAX11517.1 - 4.2e-06 26.1 2.1 1.4e-05 24.4 0.5 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GAX11517.1 - 8e-06 25.3 0.1 1.5e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 GAX11517.1 - 0.0031 16.4 0.0 0.0062 15.4 0.0 1.4 1 0 0 1 1 1 1 MCRA family FAD_binding_2 PF00890.24 GAX11517.1 - 0.0032 16.6 0.7 0.011 14.8 0.2 1.9 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 GAX11517.1 - 0.006 17.1 0.0 0.038 14.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX11517.1 - 0.0066 15.5 0.1 0.042 12.9 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 GAX11517.1 - 0.01 14.7 0.3 0.018 13.9 0.3 1.4 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 GAX11517.1 - 0.018 13.7 0.3 0.018 13.7 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 GAX11517.1 - 0.22 10.8 0.0 0.85 8.9 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SUIM_assoc PF16619.5 GAX11517.1 - 2.1 8.5 8.2 4.9 7.3 8.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FAD_oxidored PF12831.7 GAX11517.1 - 4.1 6.6 5.0 14 4.9 4.9 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase E6 PF00518.17 GAX11518.1 - 0.072 13.5 0.8 0.18 12.3 0.8 1.7 1 0 0 1 1 1 0 Early Protein (E6) DnaJ PF00226.31 GAX11520.1 - 1.8e-18 66.4 2.8 6.7e-18 64.6 2.8 2.0 1 0 0 1 1 1 1 DnaJ domain Phage-MuB_C PF09077.11 GAX11520.1 - 0.0025 17.7 0.6 4.9 7.1 0.0 3.4 3 1 0 3 3 3 2 Mu B transposition protein, C terminal DUF4175 PF13779.6 GAX11520.1 - 0.017 13.1 7.9 0.0072 14.3 5.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF3246 PF11596.8 GAX11520.1 - 0.54 9.7 6.7 0.03 13.8 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Mis14 PF08641.12 GAX11520.1 - 1.9 8.8 12.5 0.7 10.2 8.1 2.4 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Aa_trans PF01490.18 GAX11521.1 - 7.2e-34 117.2 21.2 5.1e-33 114.4 21.2 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DNA_pol_A_exo1 PF01612.20 GAX11522.1 - 9.8e-17 61.2 0.0 1.5e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 GAX11522.1 - 1.4e-05 25.0 0.3 4.8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 HRDC domain Pyr_redox_2 PF07992.14 GAX11523.1 - 7.8e-28 97.6 0.2 4.8e-27 94.9 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GAX11523.1 - 1.9e-22 79.2 0.2 3.1e-22 78.5 0.2 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 GAX11523.1 - 3.3e-11 43.6 0.0 2.9e-07 30.9 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX11523.1 - 3.5e-09 36.7 0.0 1e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAX11523.1 - 1e-08 34.9 0.3 0.0042 16.4 0.1 3.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAX11523.1 - 4.6e-07 29.5 0.0 7.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAX11523.1 - 2.3e-06 26.6 0.2 4.6e-05 22.3 0.2 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAX11523.1 - 3.7e-06 26.6 0.1 3.7e-06 26.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAX11523.1 - 4.4e-06 26.1 0.2 0.00052 19.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAX11523.1 - 0.00013 21.7 3.6 0.0032 17.1 0.1 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 GAX11523.1 - 0.00053 19.4 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 GAX11523.1 - 0.00053 19.2 0.3 0.0074 15.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAX11523.1 - 0.00077 18.7 0.0 0.00077 18.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAX11523.1 - 0.0011 18.3 0.1 0.065 12.5 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 GAX11523.1 - 0.0016 17.8 0.1 0.0016 17.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GAX11523.1 - 0.0038 17.2 0.1 0.2 11.6 0.0 2.9 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 GAX11523.1 - 0.0067 16.9 0.2 0.82 10.1 0.0 2.7 3 0 0 3 3 2 1 Putative NAD(P)-binding FMO-like PF00743.19 GAX11523.1 - 0.0091 14.5 0.0 0.11 10.9 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like YjeF_N PF03853.15 GAX11523.1 - 0.011 15.6 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus K_oxygenase PF13434.6 GAX11523.1 - 0.033 13.3 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.23 GAX11523.1 - 0.035 14.1 0.0 0.085 12.8 0.0 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.21 GAX11523.1 - 0.036 14.1 0.1 9.4 6.3 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 GAX11523.1 - 0.21 11.6 0.1 15 5.7 0.0 2.5 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 GAX11524.1 - 4.9e-61 206.5 2.7 8.6e-61 205.7 2.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX11524.1 - 6.2e-30 103.7 0.6 1.5e-29 102.5 0.2 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX11524.1 - 1.3e-18 67.3 8.7 3.1e-18 66.1 0.7 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX11524.1 - 8.1e-15 54.9 0.4 6.7e-12 45.3 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX11524.1 - 7.9e-06 25.2 4.5 8.8e-06 25.0 0.1 2.6 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAX11524.1 - 5e-05 22.8 0.5 9.4e-05 21.9 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX11524.1 - 0.00078 18.3 3.5 0.24 10.0 0.9 2.7 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 GAX11524.1 - 0.0016 17.7 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 GAX11524.1 - 0.017 15.6 0.5 3.7 8.0 0.1 2.8 3 1 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAX11524.1 - 0.036 13.1 0.5 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 GAX11524.1 - 0.045 13.0 0.2 0.14 11.4 0.2 1.8 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 GAX11524.1 - 0.057 12.7 4.0 1.3 8.3 0.6 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAX11524.1 - 0.057 13.3 0.3 0.057 13.3 0.3 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 GAX11524.1 - 0.28 10.7 7.5 1.1 8.7 0.9 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX11524.1 - 0.68 9.0 8.4 0.31 10.1 3.2 2.7 3 1 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 GAX11524.1 - 7.9 6.8 7.8 0.32 11.2 1.3 2.1 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain TPR_2 PF07719.17 GAX11525.1 - 1.7e-05 24.6 0.1 0.33 11.2 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11525.1 - 0.00064 19.7 0.7 0.14 12.4 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX11525.1 - 0.00087 19.5 0.0 0.71 10.2 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX11525.1 - 0.039 13.8 0.2 9.5 6.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Choline_kinase PF01633.20 GAX11528.1 - 2.5e-13 50.1 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAX11528.1 - 3.3e-11 43.6 0.0 6.8e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX11528.1 - 0.0034 17.0 0.0 0.25 10.9 0.0 2.8 2 1 1 3 3 3 1 RIO1 family AAA_5 PF07728.14 GAX11531.1 - 4.4e-70 234.1 0.0 3.2e-26 92.0 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX11531.1 - 2e-06 28.3 5.5 0.63 10.4 0.0 5.2 4 2 1 6 6 6 2 AAA ATPase domain AAA PF00004.29 GAX11531.1 - 2.8e-06 27.8 0.0 0.66 10.4 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) VWA_2 PF13519.6 GAX11531.1 - 0.00051 20.6 0.1 0.0014 19.3 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain TIP49 PF06068.13 GAX11531.1 - 0.0026 17.0 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 GAX11531.1 - 0.003 17.0 0.4 1.1 8.6 0.0 3.4 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 GAX11531.1 - 0.015 15.4 0.0 6.2 6.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) VWA PF00092.28 GAX11531.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain IstB_IS21 PF01695.17 GAX11531.1 - 0.039 13.7 0.0 9 6.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein RuvB_N PF05496.12 GAX11531.1 - 0.075 12.8 0.0 2.1 8.1 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 GAX11531.1 - 0.078 12.9 0.1 14 5.5 0.0 3.6 4 0 0 4 4 4 0 NACHT domain ABC_tran PF00005.27 GAX11531.1 - 0.15 12.5 0.0 0.64 10.5 0.0 2.1 1 0 0 1 1 1 0 ABC transporter B2 PF11473.8 GAX11531.1 - 0.16 11.8 0.1 0.45 10.3 0.1 1.7 1 0 0 1 1 1 0 RNA binding protein B2 E1_dh PF00676.20 GAX11532.1 - 4.9e-51 173.4 0.0 9.2e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.20 GAX11532.1 - 1.3e-25 89.7 0.1 5.7e-25 87.6 0.1 2.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 GAX11532.1 - 6.8e-14 51.9 0.0 1.7e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 GAX11532.1 - 0.0018 18.1 2.3 0.0024 17.7 0.2 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 GAX11532.1 - 0.0036 17.6 0.0 0.02 15.2 0.0 2.3 1 1 1 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II DXP_synthase_N PF13292.6 GAX11532.1 - 0.03 13.5 0.1 0.055 12.7 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase FAM91_C PF14648.6 GAX11532.1 - 0.061 12.2 0.1 0.095 11.5 0.1 1.2 1 0 0 1 1 1 0 FAM91 C-terminus DUF3884 PF13024.6 GAX11533.1 - 0.036 13.6 0.2 0.062 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) PLU-1 PF08429.11 GAX11534.1 - 3e-40 138.5 47.7 6.2e-14 51.9 3.7 7.5 4 1 2 7 7 7 6 PLU-1-like protein PHD PF00628.29 GAX11534.1 - 3.6e-21 74.8 24.3 2.2e-10 40.2 11.0 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 GAX11534.1 - 0.035 13.6 17.5 0.3 10.7 3.1 2.6 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 GAX11534.1 - 0.12 12.5 11.7 0.33 11.1 4.8 2.8 2 0 0 2 2 2 0 PHD-finger PHD_3 PF13922.6 GAX11534.1 - 0.82 10.1 6.2 1.8 9.0 0.7 2.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx TMEM43 PF07787.12 GAX11535.1 - 1.8e-68 230.7 0.1 2.3e-68 230.3 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 43 U3snoRNP10 PF12397.8 GAX11536.1 - 3e-09 37.2 0.1 3e-09 37.2 0.1 5.5 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 BP28CT PF08146.12 GAX11536.1 - 4.7e-09 36.3 0.0 3.1e-08 33.6 0.0 2.5 1 0 0 1 1 1 1 BP28CT (NUC211) domain Tti2 PF10521.9 GAX11536.1 - 0.013 15.0 0.2 1.9 7.9 0.3 3.1 2 0 0 2 2 2 0 Tti2 family HEAT_2 PF13646.6 GAX11536.1 - 0.32 11.4 8.0 19 5.8 0.4 4.9 6 0 0 6 6 6 0 HEAT repeats Methyltransf_16 PF10294.9 GAX11537.1 - 1.9e-18 66.8 0.0 4.3e-17 62.4 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Glutaredoxin PF00462.24 GAX11538.1 - 0.011 15.9 0.0 0.044 14.0 0.0 2.1 2 1 0 2 2 2 0 Glutaredoxin TLD PF07534.16 GAX11539.1 - 1.9e-20 73.5 0.0 4.7e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 GAX11539.1 - 1.6e-08 34.5 0.0 2.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rotamase PF00639.21 GAX11540.1 - 4.3e-22 78.9 0.0 7.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX11540.1 - 1.7e-16 60.8 0.1 3.1e-16 60.0 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 GAX11540.1 - 1.7e-08 34.4 1.3 3.2e-08 33.5 1.3 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 GAX11540.1 - 8.5e-05 23.4 0.0 0.00021 22.1 0.0 1.8 2 0 0 2 2 2 1 PPIC-type PPIASE domain X8 PF07983.13 GAX11540.1 - 0.038 14.7 0.0 0.073 13.8 0.0 1.4 1 0 0 1 1 1 0 X8 domain UBA PF00627.31 GAX11541.1 - 4.7e-13 48.8 0.1 1.4e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain ThrE_2 PF12821.7 GAX11541.1 - 0.013 15.7 0.2 0.025 14.7 0.2 1.5 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE CUE PF02845.16 GAX11541.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 CUE domain UBA_3 PF09288.10 GAX11541.1 - 0.022 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UBA_4 PF14555.6 GAX11541.1 - 0.023 14.5 0.1 0.52 10.2 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain TraL PF07178.11 GAX11541.1 - 0.046 14.2 2.1 0.13 12.8 0.0 2.7 2 1 0 3 3 3 0 TraL protein DUF1242 PF06842.12 GAX11542.1 - 1.9e-15 56.4 0.2 3.1e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LSM PF01423.22 GAX11543.1 - 2.6e-20 71.9 0.0 3.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX11543.1 - 0.061 13.5 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 GAX11543.1 - 0.069 13.3 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Chitin_synth_2 PF03142.15 GAX11544.1 - 2.8e-159 531.1 1.6 4.1e-159 530.6 1.6 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 GAX11544.1 - 1.1e-10 41.5 0.1 3.8e-09 36.6 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAX11544.1 - 1.3e-10 41.6 7.9 3.1e-10 40.3 7.9 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX11544.1 - 7.6e-08 32.5 0.3 3.6e-05 23.8 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX11544.1 - 3.5e-06 26.9 0.0 0.019 14.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX11544.1 - 0.043 13.3 0.2 0.86 9.1 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 21 FKBP_C PF00254.28 GAX11545.1 - 2.8e-12 46.8 0.0 3.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DEAD PF00270.29 GAX11546.1 - 1.1e-37 129.5 0.0 3.4e-37 127.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAX11546.1 - 9.1e-05 22.5 0.0 0.00053 20.0 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX11546.1 - 0.0014 18.9 0.0 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAX11546.1 - 0.0032 17.8 0.0 0.039 14.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF4604 PF15377.6 GAX11546.1 - 2.3 8.6 32.7 1.3 9.4 9.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF572 PF04502.13 GAX11546.1 - 9.8 5.7 23.3 3.2 7.3 10.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Sld5 PF05916.11 GAX11548.1 - 0.00016 22.1 0.0 0.00033 21.1 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 GAX11548.1 - 0.0042 17.2 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus DEAD PF00270.29 GAX11549.1 - 2.7e-25 89.1 0.1 7.5e-25 87.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX11549.1 - 3e-17 62.9 0.0 2.1e-15 57.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX11549.1 - 3.4e-09 36.9 0.0 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX11549.1 - 0.0062 16.8 1.0 0.12 12.7 1.0 2.6 1 1 0 1 1 1 1 AAA domain T4SS-DNA_transf PF02534.14 GAX11549.1 - 0.067 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AAA_34 PF13872.6 GAX11549.1 - 0.11 11.4 0.0 0.26 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SRP54 PF00448.22 GAX11549.1 - 0.2 11.3 0.2 0.76 9.4 0.2 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain SUZ PF12752.7 GAX11550.1 - 2.4e-11 44.2 2.8 2.4e-11 44.2 2.8 2.2 2 0 0 2 2 2 1 SUZ domain eIF-5_eIF-2B PF01873.17 GAX11551.1 - 2.6e-35 120.8 0.3 5.8e-35 119.7 0.3 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF4892 PF16234.5 GAX11551.1 - 0.0012 18.3 0.1 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4892) CxC1 PF18802.1 GAX11551.1 - 0.49 10.6 2.8 1.8 8.8 0.1 2.6 3 0 0 3 3 3 0 CxC1 like cysteine cluster associated with KDZ transposases NARP1 PF12569.8 GAX11551.1 - 1.4 7.7 10.5 1.8 7.4 10.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Phage_Gp23 PF10669.9 GAX11551.1 - 1.8 8.9 7.9 2.9 8.3 7.9 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SET PF00856.28 GAX11552.1 - 1.1e-09 38.9 0.1 1.4e-07 32.1 0.1 3.2 2 1 0 3 3 3 1 SET domain Bap31_Bap29_C PF18035.1 GAX11553.1 - 0.0028 17.6 6.6 0.0028 17.6 6.6 2.2 2 1 1 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain V_ATPase_I PF01496.19 GAX11553.1 - 0.0046 15.0 9.7 0.0057 14.6 9.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PIEZO PF15917.5 GAX11553.1 - 0.039 13.4 8.8 0.048 13.1 8.8 1.1 1 0 0 1 1 1 0 Piezo SH3_13 PF18335.1 GAX11553.1 - 0.1 12.4 0.5 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain RILP PF11461.8 GAX11553.1 - 0.12 12.7 0.2 0.12 12.7 0.2 3.0 2 1 1 3 3 3 0 Rab interacting lysosomal protein SPX PF03105.19 GAX11553.1 - 0.14 12.0 10.1 0.19 11.6 10.1 1.1 1 0 0 1 1 1 0 SPX domain AATF-Che1 PF13339.6 GAX11553.1 - 0.18 12.4 9.1 0.3 11.8 9.1 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4407 PF14362.6 GAX11553.1 - 0.27 10.5 8.2 0.34 10.2 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cwf_Cwc_15 PF04889.12 GAX11553.1 - 0.65 9.7 17.2 0.92 9.2 17.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ALMT PF11744.8 GAX11553.1 - 1.9 7.2 7.0 2.2 7.0 7.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Sporozoite_P67 PF05642.11 GAX11553.1 - 3 5.8 6.4 3.6 5.6 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPR_2 PF13041.6 GAX11554.1 - 0.0026 17.9 0.1 0.057 13.6 0.3 2.7 2 1 0 2 2 2 1 PPR repeat family Drc1-Sld2 PF11719.8 GAX11554.1 - 0.4 10.2 3.3 0.13 11.8 0.7 1.5 2 0 0 2 2 2 0 DNA replication and checkpoint protein YL1 PF05764.13 GAX11554.1 - 0.85 9.7 5.9 1.4 9.0 5.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SAP PF02037.27 GAX11555.1 - 1e-57 191.1 15.2 7.9e-14 51.0 0.3 5.9 6 0 0 6 6 6 5 SAP domain HeH PF12949.7 GAX11555.1 - 0.00018 21.2 6.6 0.46 10.2 0.1 5.2 4 1 0 4 4 4 3 HeH/LEM domain Telomere_Sde2_2 PF13297.6 GAX11555.1 - 0.0015 18.2 0.9 1.1 9.0 0.1 3.8 4 0 0 4 4 4 2 Telomere stability C-terminal Ish1 PF10281.9 GAX11555.1 - 0.0022 18.2 0.1 26 5.2 0.0 4.6 5 0 0 5 5 5 2 Putative stress-responsive nuclear envelope protein Laminin_EGF PF00053.24 GAX11556.1 - 0.035 14.2 1.6 0.035 14.2 1.6 4.5 3 1 1 4 4 4 0 Laminin EGF domain Nup84_Nup100 PF04121.13 GAX11557.1 - 9.6e-66 222.4 0.6 2e-64 218.0 0.6 2.2 1 1 1 2 2 2 2 Nuclear pore protein 84 / 107 FUSC PF04632.12 GAX11558.1 - 0.28 9.6 0.1 0.35 9.3 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4686 PF15742.5 GAX11559.1 - 0.037 13.2 0.5 0.06 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF2312 PF10073.9 GAX11559.1 - 0.084 12.5 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Ribosomal_L27A PF00828.19 GAX11560.1 - 1.8e-36 125.7 1.4 2.5e-36 125.2 1.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ank_2 PF12796.7 GAX11563.1 - 3.9e-13 49.8 0.2 2.3e-06 28.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) IBR PF01485.21 GAX11563.1 - 1.6e-12 47.5 20.7 1.3e-10 41.3 9.0 5.9 4 2 1 5 5 5 2 IBR domain, a half RING-finger domain Ank_4 PF13637.6 GAX11563.1 - 8.5e-12 45.4 0.4 0.00011 22.7 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX11563.1 - 7.9e-11 41.9 0.2 1.1e-06 28.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAX11563.1 - 4.6e-10 38.9 0.5 0.0013 19.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX11563.1 - 8.9e-08 32.3 0.1 0.018 15.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-CCHC PF00098.23 GAX11563.1 - 0.0065 16.5 0.9 0.037 14.1 0.9 2.5 1 0 0 1 1 1 1 Zinc knuckle Guanylate_cyc PF00211.20 GAX11564.1 - 8.3e-45 152.7 0.0 1.4e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX11564.1 - 6.3e-29 101.4 1.1 1.6e-28 100.1 1.1 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Myb_Cef PF11831.8 GAX11565.1 - 2.7e-27 95.9 12.4 2.7e-27 95.9 12.4 3.2 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 GAX11565.1 - 8.6e-19 67.5 7.3 4.3e-09 36.4 2.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX11565.1 - 1.5e-17 63.5 6.2 4e-11 43.0 3.6 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 GAX11565.1 - 0.016 15.3 1.1 1.4 9.0 1.1 3.8 4 1 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Cep57_MT_bd PF06657.13 GAX11565.1 - 5 7.7 12.8 0.37 11.3 0.4 4.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Cpn10 PF00166.21 GAX11566.1 - 1.2e-29 102.2 0.0 1.3e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cupin_6 PF12852.7 GAX11566.1 - 0.026 14.2 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Cupin PRMT5 PF05185.16 GAX11567.1 - 7e-10 39.0 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.6 GAX11567.1 - 4.8e-09 36.8 0.0 9e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX11567.1 - 3e-07 30.4 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX11567.1 - 3.3e-07 30.3 0.2 2.3e-05 24.2 0.1 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAX11567.1 - 2.9e-06 27.4 0.2 7.4e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX11567.1 - 6.2e-06 25.9 0.1 1.4e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 GAX11567.1 - 0.00014 22.5 0.0 0.00061 20.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GAX11567.1 - 0.00053 19.4 0.3 0.0019 17.5 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 GAX11567.1 - 0.00058 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 GAX11567.1 - 0.00072 19.0 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 GAX11567.1 - 0.00079 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX11567.1 - 0.003 17.4 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 GAX11567.1 - 0.0048 16.8 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_12 PF08242.12 GAX11567.1 - 0.0072 17.1 0.0 0.025 15.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX11567.1 - 0.012 15.4 0.2 0.024 14.4 0.2 1.4 1 0 0 1 1 1 0 Lysine methyltransferase StbA PF06406.11 GAX11567.1 - 0.027 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 StbA protein CheR PF01739.18 GAX11567.1 - 0.084 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_3 PF01596.17 GAX11567.1 - 0.16 11.2 0.1 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase HMG_box PF00505.19 GAX11568.1 - 1.5e-12 47.8 10.7 2.2e-11 44.0 10.7 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX11568.1 - 2.7e-11 43.9 7.5 5.4e-11 42.9 7.5 1.6 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 GAX11568.1 - 0.092 13.3 0.6 0.092 13.3 0.6 2.1 2 0 0 2 2 2 0 YABBY protein SR-25 PF10500.9 GAX11568.1 - 3.6 7.1 16.2 0.14 11.8 6.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fructosamin_kin PF03881.14 GAX11569.1 - 3.8e-71 239.7 0.0 4.4e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 GAX11569.1 - 2.1e-06 27.8 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DnaJ PF00226.31 GAX11570.1 - 8.6e-15 54.6 0.2 1.9e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3395 PF11875.8 GAX11570.1 - 0.00025 21.0 5.7 0.0003 20.7 1.4 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3395) DUF573 PF04504.14 GAX11570.1 - 0.44 11.2 3.6 16 6.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF573 SnoaL_3 PF13474.6 GAX11571.1 - 8.2e-41 139.1 0.0 2.9e-14 53.4 0.0 3.1 3 0 0 3 3 3 3 SnoaL-like domain CaMKII_AD PF08332.10 GAX11571.1 - 2.8e-38 131.0 0.0 1.2e-13 51.3 0.0 3.1 3 0 0 3 3 3 3 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 GAX11571.1 - 3.3e-27 95.0 0.0 2e-07 31.4 0.0 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 GAX11571.1 - 1e-18 67.8 0.0 2.8e-07 31.1 0.1 3.2 3 0 0 3 3 3 3 SnoaL-like domain DUF3225 PF11533.8 GAX11571.1 - 8.1e-15 54.7 0.1 0.00018 21.2 0.0 4.0 4 1 0 4 4 4 3 Protein of unknown function (DUF3225) SnoaL_4 PF13577.6 GAX11571.1 - 9.3e-13 48.4 1.2 0.00071 19.7 0.0 4.8 3 2 0 3 3 3 3 SnoaL-like domain Skp1 PF01466.19 GAX11571.1 - 0.98 9.6 8.1 23 5.2 0.0 4.9 5 0 0 5 5 5 0 Skp1 family, dimerisation domain Trypsin_2 PF13365.6 GAX11572.1 - 6e-16 59.7 0.3 1.4e-15 58.5 0.1 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX11572.1 - 3.9e-07 30.1 5.6 9.4e-07 28.9 5.6 1.6 1 1 0 1 1 1 1 Trypsin CDC48_2 PF02933.17 GAX11572.1 - 0.024 14.4 0.0 1.4 8.7 0.0 2.6 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 Peptidase_S39 PF02122.15 GAX11572.1 - 0.1 12.1 1.0 1.5 8.3 0.2 2.2 2 0 0 2 2 2 0 Peptidase S39 Peptidase_C4 PF00863.19 GAX11572.1 - 0.14 11.4 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C4 Peptidase_S46 PF10459.9 GAX11572.1 - 0.15 10.7 4.3 1.2 7.7 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 Trypsin_2 PF13365.6 GAX11573.1 - 7.6e-15 56.1 0.1 1.5e-14 55.2 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX11573.1 - 1.1e-06 28.6 3.5 0.00014 21.7 0.0 2.5 2 0 0 2 2 2 2 Trypsin Peptidase_C4 PF00863.19 GAX11573.1 - 0.16 11.3 0.2 0.28 10.4 0.2 1.4 1 0 0 1 1 1 0 Peptidase family C4 Peptidase_S46 PF10459.9 GAX11573.1 - 0.35 9.4 3.0 4.1 5.9 0.1 2.0 2 0 0 2 2 2 0 Peptidase S46 Trypsin_2 PF13365.6 GAX11574.1 - 6.6e-19 69.3 0.0 1.6e-18 68.0 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX11574.1 - 1.7e-10 41.1 0.1 3.2e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 GAX11574.1 - 2.4e-05 23.2 0.6 0.0057 15.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_C4 PF00863.19 GAX11574.1 - 0.081 12.2 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C4 Peptidase_S7 PF00949.21 GAX11574.1 - 0.29 11.0 1.6 0.38 10.6 0.2 1.8 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease DUF3861 PF12977.7 GAX11575.1 - 0.0051 16.9 1.3 1.5 9.0 0.3 2.8 2 0 0 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) HEM4 PF02602.15 GAX11575.1 - 0.0099 15.3 0.1 0.063 12.6 0.0 2.2 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD tRNA_lig_CPD PF08302.11 GAX11575.1 - 0.071 12.5 10.3 0.06 12.8 3.1 3.1 2 1 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain DUF2666 PF10869.8 GAX11575.1 - 8.2 6.6 8.5 0.56 10.4 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2666) 4HBT PF03061.22 GAX11576.1 - 0.0016 18.7 0.2 1.9 8.9 0.0 3.2 3 0 0 3 3 3 2 Thioesterase superfamily TFIIF_alpha PF05793.12 GAX11577.1 - 0.074 11.6 4.5 0.11 11.1 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.14 GAX11577.1 - 0.11 12.3 3.5 0.17 11.7 3.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 GAX11577.1 - 0.93 9.2 7.8 1.7 8.3 7.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein XRCC4 PF06632.12 GAX11577.1 - 0.98 8.2 3.9 1.4 7.7 3.9 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 BUD22 PF09073.10 GAX11577.1 - 1.5 8.1 6.8 2.1 7.6 6.8 1.1 1 0 0 1 1 1 0 BUD22 MVP_shoulder PF11978.8 GAX11578.1 - 0.015 15.3 0.0 0.32 11.0 0.0 2.4 1 1 1 2 2 2 0 Shoulder domain bMG5 PF17972.1 GAX11578.1 - 0.051 13.9 1.8 1.7 9.0 0.1 3.0 1 1 3 4 4 4 0 Bacterial Alpha-2-macroglobulin MG5 domain FPRL1_inhibitor PF16104.5 GAX11578.1 - 0.052 13.7 1.6 0.44 10.7 0.1 2.6 1 1 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein DUF1104 PF06518.11 GAX11578.1 - 0.23 11.8 6.4 0.081 13.3 1.5 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1104) adh_short PF00106.25 GAX11579.1 - 1.4e-20 73.6 0.0 1.7e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX11579.1 - 1.8e-13 50.6 0.0 2.3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX11579.1 - 0.003 17.5 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 KR domain ABC_tran PF00005.27 GAX11581.1 - 1.8e-32 112.8 0.0 4.8e-32 111.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX11581.1 - 1.3e-28 100.5 6.0 1.6e-28 100.2 6.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAX11581.1 - 1.5e-06 27.9 0.1 2.3e-05 23.9 0.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX11581.1 - 0.00024 21.0 0.0 0.16 11.8 0.0 3.0 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX11581.1 - 0.00065 20.1 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 GAX11581.1 - 0.0051 16.6 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAX11581.1 - 0.0055 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ATP-synt_ab PF00006.25 GAX11581.1 - 0.0068 16.1 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 GAX11581.1 - 0.0072 16.0 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX11581.1 - 0.019 15.2 0.1 0.062 13.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX11581.1 - 0.02 14.9 0.7 0.28 11.3 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAX11581.1 - 0.041 14.1 0.1 0.26 11.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 GAX11581.1 - 0.052 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 GAX11581.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 GAX11581.1 - 0.058 13.9 0.2 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAX11581.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Amidohydro_1 PF01979.20 GAX11581.1 - 0.11 11.8 0.6 0.51 9.6 0.6 1.9 1 1 0 1 1 1 0 Amidohydrolase family MBR1 PF17058.5 GAX11581.1 - 0.81 10.0 3.3 1.4 9.1 3.3 1.4 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 Ank_2 PF12796.7 GAX11582.1 - 1.1e-19 70.8 0.0 2.8e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX11582.1 - 3.2e-13 49.9 0.0 7.1e-06 26.5 0.0 4.4 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX11582.1 - 6.1e-09 35.4 0.0 8.7 7.3 0.0 5.9 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 GAX11582.1 - 1.4e-06 28.4 0.0 0.061 13.7 0.0 5.1 2 2 3 6 6 6 2 Ankyrin repeats (many copies) DUF1843 PF08898.10 GAX11582.1 - 0.022 15.3 0.6 6.9 7.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Flg_new PF09479.10 GAX11582.1 - 0.06 13.5 0.0 0.99 9.6 0.0 2.6 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) CDC37_C PF08564.10 GAX11582.1 - 0.069 13.3 0.2 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Cdc37 C terminal domain Ank PF00023.30 GAX11582.1 - 0.18 12.3 0.0 46 4.7 0.0 4.0 4 1 0 4 4 4 0 Ankyrin repeat SNF2_N PF00176.23 GAX11583.1 - 6.9e-64 215.8 0.1 1.4e-63 214.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX11583.1 - 1.6e-19 70.3 0.0 3.8e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX11583.1 - 8.4e-11 42.2 0.6 2.4e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 GAX11583.1 - 2.1e-09 37.1 6.7 0.00022 21.0 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 GAX11583.1 - 1e-06 28.2 0.1 1e-06 28.2 0.1 3.1 4 0 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAX11583.1 - 0.00095 19.0 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX11583.1 - 0.0095 16.2 0.0 0.067 13.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AroM PF07302.11 GAX11583.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 AroM protein Pkinase PF00069.25 GAX11584.1 - 2.7e-36 125.3 0.0 1.2e-35 123.1 0.0 2.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11584.1 - 8.4e-33 113.7 0.0 2.3e-32 112.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX11584.1 - 0.00017 20.5 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TetR_C_8 PF14278.6 GAX11584.1 - 0.11 12.6 0.0 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Myb_DNA-binding PF00249.31 GAX11585.1 - 3.2e-13 49.6 1.5 1.1e-07 31.9 0.8 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX11585.1 - 6.9e-05 23.0 3.7 0.02 15.1 0.4 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX11585.1 - 0.00059 19.7 5.3 0.06 13.2 0.5 3.4 2 0 0 2 2 2 2 Myb DNA-binding like VRR_NUC PF08774.11 GAX11585.1 - 0.066 13.3 0.2 0.39 10.8 0.2 2.3 1 0 0 1 1 1 0 VRR-NUC domain DUF1415 PF07209.12 GAX11587.1 - 1.8e-18 66.9 0.4 2.2e-18 66.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) Imm41 PF15592.6 GAX11587.1 - 0.0014 19.0 1.2 0.015 15.6 0.1 2.1 2 0 0 2 2 2 1 Immunity protein 41 Hist_deacetyl PF00850.19 GAX11588.1 - 1.2e-82 277.8 0.1 1.5e-82 277.6 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Lipoprotein_2 PF00921.17 GAX11589.1 - 0.023 14.2 4.1 0.067 12.7 4.1 1.7 1 0 0 1 1 1 0 Borrelia lipoprotein NAGPA PF09992.9 GAX11590.1 - 4.9e-14 52.9 0.0 5.8e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Phosphodiester glycosidase IceA2 PF05862.11 GAX11590.1 - 0.043 13.8 0.3 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Nsp1_C PF05064.13 GAX11591.1 - 1.4e-14 53.9 3.6 1.4e-14 53.9 3.6 2.1 1 1 1 2 2 2 1 Nsp1-like C-terminal region ANT PF03374.14 GAX11591.1 - 0.092 13.1 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain YojJ PF10372.9 GAX11591.1 - 0.095 12.8 1.1 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF5476 PF17570.2 GAX11591.1 - 0.44 11.0 0.1 0.44 11.0 0.1 4.2 4 1 1 5 5 5 0 Family of unknown function (DUF5476) Streptin-Immun PF11083.8 GAX11591.1 - 0.48 10.9 3.9 6.8 7.2 0.5 2.9 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein Syntaxin-6_N PF09177.11 GAX11591.1 - 0.62 10.6 5.5 1.7 9.2 0.2 2.6 1 1 0 2 2 2 0 Syntaxin 6, N-terminal BORCS7 PF16088.5 GAX11591.1 - 1.3 9.3 4.1 1.2 9.4 1.1 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Laminin_II PF06009.12 GAX11591.1 - 4.1 7.4 8.5 13 5.8 1.0 2.5 1 1 0 2 2 2 0 Laminin Domain II Sugarporin_N PF11471.8 GAX11591.1 - 9.5 6.3 7.5 7.6 6.6 0.9 3.8 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension CorA PF01544.18 GAX11591.1 - 9.7 5.4 10.5 4.8 6.4 4.9 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ECH_1 PF00378.20 GAX11592.1 - 4.5e-81 271.8 0.6 5.6e-81 271.5 0.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX11592.1 - 7.8e-40 137.4 2.4 6.3e-35 121.3 0.4 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ABC2_membrane PF01061.24 GAX11593.1 - 1.4e-31 109.6 3.5 1.9e-31 109.1 3.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX11593.1 - 3.5e-22 79.4 0.0 8.1e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAX11593.1 - 1.2e-06 28.5 0.0 0.0018 18.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX11593.1 - 4.6e-06 26.2 0.1 0.019 14.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAX11593.1 - 6.7e-05 23.3 0.3 0.00057 20.3 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 GAX11593.1 - 0.00036 20.5 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 GAX11593.1 - 0.0044 16.6 0.7 0.4 10.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 GAX11593.1 - 0.0047 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAX11593.1 - 0.0074 16.6 0.0 0.045 14.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 GAX11593.1 - 0.031 14.0 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 GAX11593.1 - 0.032 13.9 0.2 0.089 12.5 0.2 1.8 1 0 0 1 1 1 0 Cytidylate kinase SbcCD_C PF13558.6 GAX11593.1 - 0.044 14.0 0.1 0.17 12.1 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAX11593.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAX11593.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 GAX11593.1 - 0.082 12.8 0.0 7.8 6.4 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 GAX11593.1 - 0.088 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAX11593.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase LRR_6 PF13516.6 GAX11594.1 - 8.3e-07 28.6 2.3 2.8e-05 23.8 0.4 3.8 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 GAX11594.1 - 0.045 14.2 1.4 0.44 11.0 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX11594.1 - 0.081 12.7 0.6 0.42 10.4 0.2 2.5 2 1 0 2 2 2 0 Leucine rich repeat 2OG-FeII_Oxy PF03171.20 GAX11595.1 - 9e-07 29.3 0.0 1.7e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF563 PF04577.14 GAX11596.1 - 1.1e-15 58.3 0.0 1.3e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF2407 PF10302.9 GAX11597.1 - 1.3e-05 25.7 0.5 4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 GAX11597.1 - 0.0017 18.0 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UreF PF01730.16 GAX11597.1 - 0.037 14.6 1.8 0.061 13.9 1.8 1.3 1 0 0 1 1 1 0 UreF 2_5_RNA_ligase2 PF13563.6 GAX11597.1 - 0.042 13.7 0.8 0.46 10.4 0.8 2.2 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily mono-CXXC PF15626.6 GAX11597.1 - 2.9 8.3 5.5 16 6.0 0.1 2.7 2 0 0 2 2 2 0 single CXXC unit RNA_pol_Rpc4 PF05132.14 GAX11597.1 - 4.5 7.7 6.0 6.2 7.2 0.8 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Glyco_tranf_2_4 PF13704.6 GAX11598.1 - 0.00014 22.4 0.2 0.00039 20.9 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Nucleotid_trans PF03407.16 GAX11599.1 - 6e-25 88.5 0.4 8.9e-25 87.9 0.4 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Hexapep PF00132.24 GAX11600.1 - 3.1e-07 29.8 9.6 0.0024 17.6 0.2 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAX11600.1 - 0.002 17.2 0.2 0.0027 16.7 0.2 1.3 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 GAX11600.1 - 0.0069 16.1 8.4 0.068 12.9 2.5 3.3 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase XPA_C PF05181.12 GAX11601.1 - 1.2e-08 34.8 0.0 3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 XPA protein C-terminus Prenyltrans PF00432.21 GAX11602.1 - 4.4e-34 115.9 17.4 7.6e-10 38.4 1.2 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat GRASP55_65 PF04495.14 GAX11603.1 - 1.7e-60 203.3 0.0 2.8e-43 147.5 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 GAX11603.1 - 1.5e-07 31.2 0.0 0.027 14.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 GAX11603.1 - 1.6e-06 28.3 0.0 0.004 17.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Glutaredoxin PF00462.24 GAX11604.1 - 4.2e-21 74.9 0.0 5.5e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 GAX11604.1 - 0.014 15.8 0.2 0.024 15.1 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain GST_N_2 PF13409.6 GAX11604.1 - 0.066 13.5 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 GAX11604.1 - 0.087 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.20 GAX11604.1 - 0.1 12.3 1.6 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain RRM_1 PF00076.22 GAX11605.1 - 3.3e-39 132.5 0.0 3.4e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX11605.1 - 1.3e-07 31.2 0.0 0.011 15.3 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 GAX11605.1 - 0.0031 17.2 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_7 PF16367.5 GAX11605.1 - 0.0047 17.0 0.0 0.18 11.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif Peripla_BP_4 PF13407.6 GAX11605.1 - 0.081 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Glutaredoxin PF00462.24 GAX11606.1 - 1.1e-08 35.1 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 GAX11606.1 - 0.16 12.4 0.0 0.67 10.4 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Nucleotid_trans PF03407.16 GAX11607.1 - 2.9e-27 96.0 0.4 4e-27 95.6 0.4 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TRM PF02005.16 GAX11608.1 - 2.9e-114 382.2 0.0 3.8e-114 381.8 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 GAX11608.1 - 0.005 16.6 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GAX11608.1 - 0.023 15.4 0.1 0.25 12.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 GAX11608.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Mur_ligase PF01225.25 GAX11608.1 - 0.074 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Adeno_GP19K PF04881.13 GAX11608.1 - 0.083 12.9 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Adenovirus GP19K MTS PF05175.14 GAX11608.1 - 0.089 12.3 0.1 0.19 11.2 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 GAX11608.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Asp PF00026.23 GAX11609.1 - 1.1e-99 333.8 0.6 1.3e-99 333.6 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAX11609.1 - 1.1e-14 55.0 0.6 2e-12 47.7 0.6 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAX11609.1 - 0.036 14.7 0.1 24 5.6 0.0 3.3 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 GAX11609.1 - 0.044 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Adaptin_N PF01602.20 GAX11610.1 - 2.3e-79 267.3 0.9 3e-79 267.0 0.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 GAX11610.1 - 8.6e-15 54.9 0.0 1.9e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 GAX11610.1 - 1.2e-08 35.2 0.9 9.8e-08 32.2 0.1 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX11610.1 - 1.6e-05 25.3 2.4 1.3 9.6 0.0 5.2 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 GAX11610.1 - 0.006 16.7 1.8 0.68 10.3 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat TIP120 PF08623.10 GAX11610.1 - 0.87 9.3 2.6 4.4 7.1 0.1 2.6 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) zf-C2H2 PF00096.26 GAX11611.1 - 1.8e-06 28.1 9.9 4.1e-05 23.8 2.9 5.9 8 0 0 8 8 6 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 GAX11611.1 - 1.1e-05 25.6 4.9 0.0041 17.4 0.7 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 GAX11611.1 - 0.00017 22.1 9.7 0.0036 18.0 1.8 6.4 6 2 1 7 7 6 3 C2H2-type zinc finger zf-met PF12874.7 GAX11611.1 - 0.00063 20.1 2.4 0.0042 17.4 1.7 4.2 4 0 0 4 4 3 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 GAX11611.1 - 0.0012 18.9 0.9 0.0012 18.9 0.9 5.5 4 1 0 4 4 3 1 Zinc ribbon domain zf-C2H2_6 PF13912.6 GAX11611.1 - 0.0026 17.7 1.1 0.0026 17.7 1.1 4.4 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 GAX11611.1 - 0.014 15.2 1.6 0.014 15.2 1.6 5.6 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 GAX11611.1 - 0.014 15.7 0.6 0.014 15.7 0.6 4.3 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding Stc1 PF12898.7 GAX11611.1 - 0.048 14.2 24.6 0.23 12.0 1.0 3.7 2 1 0 2 2 2 0 Stc1 domain zf-H2C2_2 PF13465.6 GAX11611.1 - 0.049 14.1 0.2 0.049 14.1 0.2 5.1 6 0 0 6 6 4 0 Zinc-finger double domain zf-C2HE PF16278.5 GAX11611.1 - 0.26 11.8 8.1 0.51 10.8 2.2 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 GAX11611.1 - 0.7 10.3 19.8 0.81 10.1 3.9 3.8 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 GAX11611.1 - 3.2 7.5 10.9 3.8 7.2 0.3 3.7 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain TauE PF01925.19 GAX11612.1 - 3.8e-26 92.2 26.0 2e-13 50.5 6.2 2.7 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE PMSR PF01625.21 GAX11613.1 - 9.2e-10 38.9 1.4 2.7e-09 37.4 1.4 1.7 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase SDA1 PF05285.12 GAX11614.1 - 0.26 10.7 58.0 0.072 12.5 19.0 3.4 3 0 0 3 3 3 0 SDA1 PPTA PF01239.22 GAX11615.1 - 1.6e-26 91.2 16.0 2.4e-08 33.4 0.1 6.1 5 1 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat LOR PF04525.12 GAX11617.1 - 0.047 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 LURP-one-related Peptidase_M6 PF05547.11 GAX11620.1 - 2.1e-05 23.1 2.0 9.4e-05 20.9 2.0 2.1 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 CbtB PF09489.10 GAX11621.1 - 0.73 10.0 3.3 9.2 6.5 1.6 2.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) PPR_2 PF13041.6 GAX11622.1 - 9.7e-57 189.0 0.1 1.4e-11 44.4 0.0 14.1 8 3 7 15 15 15 10 PPR repeat family PPR_3 PF13812.6 GAX11622.1 - 8.1e-47 157.1 0.0 1.9e-07 31.0 0.0 9.7 6 3 4 10 10 10 8 Pentatricopeptide repeat domain PPR PF01535.20 GAX11622.1 - 1.8e-43 143.7 1.2 0.00022 21.2 0.0 14.7 15 0 0 15 15 15 8 PPR repeat PPR_1 PF12854.7 GAX11622.1 - 9.7e-31 105.2 0.2 0.0096 15.6 0.0 13.7 15 0 0 15 15 13 7 PPR repeat PPR_long PF17177.4 GAX11622.1 - 6.4e-29 100.8 7.4 1.3e-08 34.5 0.2 6.0 1 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GAX11622.1 - 4.6e-12 45.7 27.7 1.3 10.0 0.1 11.7 8 3 4 12 12 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX11622.1 - 1.7e-05 24.5 3.3 0.4 10.8 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat COX5A PF02284.16 GAX11622.1 - 2.4e-05 24.3 1.9 5.3 7.1 0.0 5.1 4 1 1 5 5 5 1 Cytochrome c oxidase subunit Va TPR_19 PF14559.6 GAX11622.1 - 0.0011 19.5 18.7 7 7.2 0.1 7.0 4 2 4 8 8 8 1 Tetratricopeptide repeat DUF3368 PF11848.8 GAX11622.1 - 0.017 14.9 1.0 2.6 7.9 0.0 4.6 5 1 1 6 6 5 0 Domain of unknown function (DUF3368) TPR_12 PF13424.6 GAX11622.1 - 0.027 14.7 22.5 0.72 10.2 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11622.1 - 0.034 14.4 0.0 43 4.7 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX11622.1 - 0.048 14.3 15.8 1.9 9.2 0.0 6.4 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX11622.1 - 0.049 14.3 17.6 2.9 8.7 0.1 7.1 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX11622.1 - 0.068 13.3 17.9 1.9 8.8 0.0 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_5 PF12688.7 GAX11622.1 - 0.19 12.0 5.6 7.5 6.8 1.0 4.9 5 1 0 5 5 5 0 Tetratrico peptide repeat TPR_11 PF13414.6 GAX11622.1 - 0.39 10.4 2.5 1.8 8.3 0.0 3.6 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.28 GAX11622.1 - 0.41 10.6 4.5 9.4 6.3 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX11622.1 - 0.83 9.6 6.3 27 4.8 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAX11622.1 - 1.9 8.3 17.5 0.55 10.1 0.1 5.1 4 2 2 6 6 5 0 Virulence factor membrane-bound polymerase, C-terminal Neuroparsin PF07327.11 GAX11623.1 - 1.2 9.6 10.0 0.29 11.6 6.3 1.8 1 1 0 1 1 1 0 Neuroparsin MMR_HSR1 PF01926.23 GAX11624.1 - 1.3e-41 141.3 0.0 9.4e-22 77.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 GAX11624.1 - 3e-20 72.3 0.3 1.9e-19 69.7 0.2 2.2 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 GAX11624.1 - 3.8e-18 65.5 0.0 1.5e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 GAX11624.1 - 1.7e-14 54.0 0.0 1.2e-08 35.2 0.0 4.0 3 1 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAX11624.1 - 4.2e-14 52.5 0.0 6e-07 29.2 0.1 4.7 3 2 0 4 4 4 2 Elongation factor Tu GTP binding domain Arf PF00025.21 GAX11624.1 - 2.6e-09 36.8 0.1 1.3e-05 24.7 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family Dynamin_N PF00350.23 GAX11624.1 - 1.2e-08 35.2 0.1 0.026 14.6 0.1 3.7 3 1 1 4 4 3 3 Dynamin family RsgA_GTPase PF03193.16 GAX11624.1 - 1.4e-08 34.8 0.1 0.12 12.2 0.0 3.9 4 0 0 4 4 4 2 RsgA GTPase Ras PF00071.22 GAX11624.1 - 8.5e-08 32.0 0.0 0.00062 19.4 0.0 3.0 3 1 0 3 3 3 2 Ras family ABC_tran PF00005.27 GAX11624.1 - 2.4e-06 28.1 0.0 0.015 15.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Septin PF00735.18 GAX11624.1 - 5.1e-05 22.7 0.1 1.5 8.1 0.0 3.1 3 0 0 3 3 3 2 Septin SRPRB PF09439.10 GAX11624.1 - 5.9e-05 22.6 0.0 0.00057 19.4 0.0 2.4 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AIG1 PF04548.16 GAX11624.1 - 7.1e-05 22.2 0.0 0.001 18.5 0.0 2.5 2 1 0 2 2 2 1 AIG1 family AAA_22 PF13401.6 GAX11624.1 - 9.2e-05 22.7 0.1 0.39 11.0 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAX11624.1 - 0.00011 22.6 0.6 0.75 10.1 0.1 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 GAX11624.1 - 0.00031 20.5 0.0 0.5 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX11624.1 - 0.00035 21.1 0.0 0.47 11.0 0.0 3.7 2 2 0 3 3 3 1 AAA domain cobW PF02492.19 GAX11624.1 - 0.00061 19.4 0.4 1.2 8.7 0.1 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAX11624.1 - 0.001 19.4 0.0 0.97 9.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 GAX11624.1 - 0.0015 18.7 1.9 0.092 12.9 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAX11624.1 - 0.0057 16.4 0.0 4.9 7.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain TniB PF05621.11 GAX11624.1 - 0.0093 15.4 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 GAX11624.1 - 0.012 15.7 0.1 0.12 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAX11624.1 - 0.012 14.8 0.0 0.98 8.5 0.0 3.0 2 1 1 3 3 3 0 NB-ARC domain AAA_28 PF13521.6 GAX11624.1 - 0.014 15.7 0.3 1.4 9.1 0.0 3.0 2 1 0 3 3 3 0 AAA domain OB_NTP_bind PF07717.16 GAX11624.1 - 0.052 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold NTPase_1 PF03266.15 GAX11624.1 - 0.056 13.4 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA PF00004.29 GAX11624.1 - 0.074 13.5 0.8 10 6.5 0.0 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 GAX11624.1 - 0.081 11.9 2.8 16 4.4 0.0 3.9 4 1 1 5 5 5 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 GAX11624.1 - 0.087 12.6 0.0 22 4.7 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Nuc_deoxyri_tr2 PF15891.5 GAX11624.1 - 0.11 12.9 4.1 7.4 6.9 0.0 2.9 3 0 0 3 3 2 0 Nucleoside 2-deoxyribosyltransferase like ATPase_2 PF01637.18 GAX11624.1 - 0.11 12.4 0.0 24 4.7 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAX11624.1 - 0.13 12.3 0.0 19 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 GAX11625.1 - 6e-34 117.6 0.0 5.2e-33 114.5 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11625.1 - 8.4e-33 113.7 0.0 1.2e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX11625.1 - 0.015 15.3 0.4 0.026 14.4 0.4 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.29 GAX11626.1 - 8e-19 68.1 0.0 1.5e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX11626.1 - 9e-11 42.1 0.0 3e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX11626.1 - 2.3e-10 40.8 0.0 4.7e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ORF6C PF10552.9 GAX11626.1 - 0.31 11.2 1.6 0.61 10.2 1.6 1.5 1 0 0 1 1 1 0 ORF6C domain HMG_box PF00505.19 GAX11627.1 - 5.3e-05 23.6 6.3 9.6e-05 22.7 5.4 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box F_bP_aldolase PF01116.20 GAX11629.1 - 2.7e-86 289.5 0.0 3.1e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PDZ PF00595.24 GAX11630.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain ShK PF01549.24 GAX11630.1 - 0.27 11.8 1.9 1.4 9.6 1.9 2.3 1 1 0 1 1 1 0 ShK domain-like Apyrase PF06079.11 GAX11631.1 - 2.1e-98 329.1 0.1 2.7e-98 328.8 0.1 1.1 1 0 0 1 1 1 1 Apyrase Abhydrolase_2 PF02230.16 GAX11632.1 - 1.4e-52 178.6 0.0 1.8e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 GAX11632.1 - 1.1e-08 35.1 0.0 4.2e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 GAX11632.1 - 1.7e-08 34.1 2.5 0.049 12.9 0.0 3.2 2 1 1 3 3 3 3 Serine aminopeptidase, S33 DLH PF01738.18 GAX11632.1 - 2.3e-06 27.3 0.0 7.9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX11632.1 - 1.3e-05 24.8 0.6 0.0002 20.9 0.1 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAX11632.1 - 0.00015 22.5 0.0 0.00018 22.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 GAX11632.1 - 0.00021 21.1 0.0 0.00044 20.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 GAX11632.1 - 0.0042 16.6 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 GAX11632.1 - 0.0043 16.9 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 GAX11632.1 - 0.0053 16.4 0.7 0.93 9.1 0.3 3.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 GAX11632.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase LIP PF03583.14 GAX11632.1 - 0.031 13.6 0.2 0.066 12.5 0.2 1.6 1 1 0 1 1 1 0 Secretory lipase BAAT_C PF08840.11 GAX11632.1 - 0.062 13.2 0.8 2.1 8.2 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 GAX11632.1 - 0.081 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 GAX11632.1 - 0.09 12.9 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 TAP-like protein pPIWI_RE_REase PF18154.1 GAX11632.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 REase associating with pPIWI_RE Pkinase PF00069.25 GAX11633.1 - 7.7e-15 55.0 0.0 9.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11633.1 - 4.6e-07 29.4 0.0 6.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX11633.1 - 4.5e-06 25.7 0.0 5.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX11633.1 - 0.00064 19.7 0.0 0.00097 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX11633.1 - 0.086 12.2 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_1 PF00561.20 GAX11634.1 - 2.3e-27 96.3 0.1 1.1e-25 90.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX11634.1 - 6e-20 72.8 3.3 7.6e-20 72.5 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX11634.1 - 9e-12 44.8 0.4 3.5e-11 42.9 0.4 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAX11634.1 - 3.6e-08 33.4 0.1 5.2e-07 29.6 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 GAX11634.1 - 2.3e-05 24.6 0.0 3.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 GAX11634.1 - 4.3e-05 23.3 0.0 7.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Putative esterase DUF676 PF05057.14 GAX11634.1 - 0.00042 19.9 0.0 0.00059 19.4 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 GAX11634.1 - 0.00067 19.5 0.0 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 GAX11634.1 - 0.0017 17.1 0.0 0.0037 16.0 0.0 1.5 2 0 0 2 2 2 1 Ndr family Lipase_3 PF01764.25 GAX11634.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 GAX11634.1 - 0.026 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 GAX11634.1 - 0.028 14.0 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family EHN PF06441.12 GAX11634.1 - 0.033 14.5 0.1 0.096 13.1 0.0 1.9 2 0 0 2 2 2 0 Epoxide hydrolase N terminus DUF915 PF06028.11 GAX11634.1 - 0.037 13.3 0.0 0.83 8.9 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydro_lipase PF04083.16 GAX11634.1 - 0.041 13.5 0.2 0.1 12.2 0.0 1.8 2 0 0 2 2 1 0 Partial alpha/beta-hydrolase lipase region PAC2 PF09754.9 GAX11634.1 - 0.05 13.6 0.0 0.091 12.8 0.0 1.5 2 0 0 2 2 2 0 PAC2 family Chlorophyllase2 PF12740.7 GAX11634.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Palm_thioest PF02089.15 GAX11634.1 - 0.099 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LpxI_N PF17930.1 GAX11634.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain DUF2974 PF11187.8 GAX11634.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 GAX11634.1 - 0.18 11.6 0.0 2.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 GAX11634.1 - 0.18 10.8 0.1 0.27 10.2 0.1 1.4 1 1 0 1 1 1 0 Chlorophyllase WbqC PF08889.11 GAX11635.1 - 0.00041 20.3 0.6 0.00068 19.6 0.6 1.2 1 0 0 1 1 1 1 WbqC-like protein family Imm10 PF15588.6 GAX11635.1 - 0.024 14.8 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 10 zf-CDGSH PF09360.10 GAX11636.1 - 6.4e-09 35.9 0.2 1.1e-08 35.2 0.0 1.6 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type Acid_PPase PF12689.7 GAX11637.1 - 1.9e-24 86.4 0.0 3.4e-24 85.6 0.0 1.4 1 1 0 1 1 1 1 Acid Phosphatase Ribosomal_S10 PF00338.22 GAX11638.1 - 0.031 14.5 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e Ribosomal_L1 PF00687.21 GAX11638.1 - 0.038 13.7 0.3 0.098 12.4 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family Pox_H7 PF04787.12 GAX11638.1 - 0.092 13.3 2.1 0.15 12.6 0.8 2.0 2 0 0 2 2 2 0 Late protein H7 Sec34 PF04136.15 GAX11638.1 - 3.4 7.5 9.2 3.7 7.4 0.3 3.6 4 0 0 4 4 4 0 Sec34-like family ATP-synt_C PF00137.21 GAX11640.1 - 1.5e-34 118.1 37.3 5.5e-23 81.1 16.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ETF PF01012.21 GAX11641.1 - 3.6e-43 147.6 0.1 4.7e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GDA1_CD39 PF01150.17 GAX11642.1 - 1.1e-66 225.3 0.0 1.4e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pkinase PF00069.25 GAX11643.1 - 6.3e-18 65.1 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SET PF00856.28 GAX11643.1 - 1.9e-14 54.4 0.0 9.2e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 SET domain Cyclin_N PF00134.23 GAX11643.1 - 5e-05 23.1 0.2 0.00012 21.8 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Guanylate_cyc PF00211.20 GAX11644.1 - 2.8e-54 183.5 0.0 4.6e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 GAX11644.1 - 3.3e-33 115.0 0.0 6.6e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 GAX11644.1 - 1.1e-19 70.8 0.5 2.2e-09 37.1 0.6 2.4 1 1 1 2 2 2 2 Heme NO binding associated NAD_kinase PF01513.21 GAX11645.1 - 7.6e-50 169.8 0.1 1.5e-37 129.4 0.0 2.5 3 0 0 3 3 3 2 ATP-NAD kinase CRAL_TRIO PF00650.20 GAX11648.1 - 5e-31 107.6 0.1 6.8e-31 107.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX11648.1 - 0.00096 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PqiA PF04403.13 GAX11649.1 - 7.1e-06 25.9 15.3 0.0017 18.2 0.9 2.9 3 0 0 3 3 3 2 Paraquat-inducible protein A LBP_BPI_CETP PF01273.25 GAX11649.1 - 0.00026 20.6 1.0 0.00073 19.2 1.0 1.7 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain YL1 PF05764.13 GAX11650.1 - 0.087 12.9 5.9 0.16 12.1 5.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein U3_assoc_6 PF08640.11 GAX11651.1 - 2.4e-18 66.0 7.9 6.2e-18 64.7 7.9 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 GAX11651.1 - 8.3e-08 32.4 7.1 0.016 16.0 0.2 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX11651.1 - 0.0057 17.1 2.1 59 4.3 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat SET PF00856.28 GAX11651.1 - 0.052 13.9 1.0 2.2 8.7 0.2 3.2 2 1 0 2 2 2 0 SET domain Adaptin_binding PF10199.9 GAX11651.1 - 1.2 9.7 7.0 1.6 9.4 1.3 2.8 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 2OG-FeII_Oxy_3 PF13640.6 GAX11652.1 - 7.4e-12 46.0 0.0 1.4e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX11652.1 - 4.7e-05 23.8 0.0 9.9e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SNF2_N PF00176.23 GAX11653.1 - 4.3e-66 223.0 0.3 9.8e-66 221.8 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX11653.1 - 4.2e-20 72.2 0.0 2.2e-19 69.8 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 GAX11653.1 - 2.7e-08 34.0 10.6 2.7e-08 34.0 10.6 3.2 1 1 1 2 2 2 1 HSA ResIII PF04851.15 GAX11653.1 - 1.9e-05 24.7 2.9 0.00025 21.1 0.0 3.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit F-box-like PF12937.7 GAX11653.1 - 2.5e-05 24.1 0.1 2.5e-05 24.1 0.1 2.4 3 0 0 3 3 3 1 F-box-like Beta_helix PF13229.6 GAX11653.1 - 0.00098 19.0 1.5 0.0028 17.5 0.4 2.1 2 0 0 2 2 2 1 Right handed beta helix region F-box_5 PF18511.1 GAX11653.1 - 0.0087 15.6 0.0 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 F-box NosD PF05048.13 GAX11653.1 - 0.016 14.5 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) WW PF00397.26 GAX11653.1 - 0.036 14.1 0.8 0.1 12.7 0.8 1.8 1 0 0 1 1 1 0 WW domain Adeno_E1B_55K PF01696.17 GAX11653.1 - 0.072 11.8 2.9 0.12 11.0 2.9 1.3 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen F-box PF00646.33 GAX11653.1 - 0.098 12.6 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain KMP11 PF03037.16 GAX11654.1 - 0.0066 17.2 0.5 0.012 16.4 0.5 1.3 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 DGF-1_4 PF11024.8 GAX11654.1 - 0.024 15.4 5.6 0.041 14.7 5.6 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 CCDC74_C PF14917.6 GAX11654.1 - 0.03 14.8 1.2 0.078 13.5 0.1 2.1 2 1 0 2 2 2 0 Coiled coil protein 74, C terminal Pertussis_S1 PF02917.14 GAX11654.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 KxDL PF10241.9 GAX11654.1 - 0.91 9.9 6.2 9.8 6.5 3.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein SnoaL_3 PF13474.6 GAX11655.1 - 0.12 12.6 0.6 6 7.2 0.0 2.4 2 0 0 2 2 2 0 SnoaL-like domain FA_hydroxylase PF04116.13 GAX11656.1 - 2e-13 50.8 8.3 2e-13 50.8 8.3 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NAD_binding_10 PF13460.6 GAX11657.1 - 5.4e-17 62.3 0.4 6.5e-17 62.0 0.4 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX11657.1 - 0.0025 17.4 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAX11657.1 - 0.0038 16.7 0.1 0.0052 16.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAX11657.1 - 0.0063 17.0 0.1 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Peptidase_A4 PF01828.17 GAX11657.1 - 0.08 12.4 0.2 0.42 10.0 0.1 2.1 2 0 0 2 2 2 0 Peptidase A4 family SHS2_Rpb7-N PF03876.17 GAX11658.1 - 4.4e-11 43.0 0.1 1.2e-10 41.5 0.2 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 GAX11658.1 - 2.7e-07 30.8 0.0 5.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 GAX11658.1 - 0.0056 16.9 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 FKBP_C PF00254.28 GAX11659.1 - 3.5e-28 97.8 0.0 6.1e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 GAX11659.1 - 7e-05 23.7 0.0 0.00012 23.0 0.0 1.3 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FTCD_N PF07837.12 GAX11661.1 - 1.5e-09 37.9 0.1 2.2e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain Patched PF02460.18 GAX11662.1 - 5.8e-84 282.7 9.4 7.4e-84 282.3 9.4 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 GAX11662.1 - 1e-33 116.3 16.4 1e-32 113.1 9.1 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 GAX11662.1 - 0.00033 18.5 15.5 0.0012 16.6 8.3 2.3 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family HPIH PF13323.6 GAX11662.1 - 0.032 14.1 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain with HPIH motif MMPL PF03176.15 GAX11662.1 - 0.78 8.6 26.3 0.083 11.8 11.2 2.7 3 0 0 3 3 3 0 MMPL family 2-Hacid_dh_C PF02826.19 GAX11663.1 - 3.5e-48 163.3 0.1 6.6e-48 162.4 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UbiA PF01040.18 GAX11663.1 - 1e-45 156.0 14.8 1e-45 156.0 14.8 2.1 2 0 0 2 2 2 1 UbiA prenyltransferase family 2-Hacid_dh PF00389.30 GAX11663.1 - 3.4e-24 85.0 0.1 5.6e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAX11663.1 - 1.3e-05 25.4 1.8 2e-05 24.8 0.0 2.2 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 GAX11663.1 - 0.03 13.9 0.4 0.073 12.6 0.4 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain cNMP_binding PF00027.29 GAX11663.1 - 0.053 13.6 0.1 0.65 10.1 0.1 2.5 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain IlvN PF07991.12 GAX11663.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PRP1_N PF06424.12 GAX11664.1 - 0.05 14.0 0.4 0.05 14.0 0.4 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Tetraspanin PF00335.20 GAX11664.1 - 0.1 12.3 0.8 0.77 9.4 0.0 2.4 2 1 0 2 2 2 0 Tetraspanin family DUF4578 PF15147.6 GAX11664.1 - 0.22 12.4 0.3 0.22 12.4 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4578) Spem1 PF15670.5 GAX11664.1 - 1.7 8.2 5.8 0.8 9.2 2.3 1.8 2 0 0 2 2 2 0 Spermatid maturation protein 1 DUF2201_N PF13203.6 GAX11664.1 - 4.8 6.7 6.5 0.18 11.4 0.7 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain Abhydrolase_1 PF00561.20 GAX11666.1 - 6.9e-07 29.2 0.0 2e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold PrmA PF06325.13 GAX11668.1 - 8.4e-51 173.1 0.0 3.2e-36 125.3 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX11668.1 - 0.00015 21.4 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX11668.1 - 0.00067 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX11668.1 - 0.0067 16.2 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 GAX11668.1 - 0.066 13.9 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 GAX11668.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Herpes_LMP1 PF05297.11 GAX11669.1 - 0.56 9.4 3.1 1.1 8.4 3.1 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Mpv17_PMP22 PF04117.12 GAX11670.1 - 3.8e-05 23.8 0.4 7.9e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family PqiA PF04403.13 GAX11673.1 - 7.5e-12 45.3 20.5 2.4e-08 33.9 4.1 3.6 3 1 0 3 3 3 2 Paraquat-inducible protein A TMEM154 PF15102.6 GAX11673.1 - 1.4 8.9 6.4 0.96 9.4 0.1 3.0 2 1 1 3 3 3 0 TMEM154 protein family Chitin_synth_2 PF03142.15 GAX11674.1 - 3e-163 544.2 4.2 4.2e-163 543.7 4.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAX11674.1 - 4.3e-13 49.7 0.1 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAX11674.1 - 1.6e-11 44.5 5.7 4.2e-11 43.1 5.7 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAX11674.1 - 6.1e-09 35.9 0.0 0.00013 21.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX11674.1 - 3.8e-05 23.2 0.0 0.082 12.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 Cyt-b5 PF00173.28 GAX11674.1 - 0.00055 20.0 0.1 0.42 10.8 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Chorion_2 PF03964.15 GAX11674.1 - 0.044 14.6 0.7 0.044 14.6 0.7 2.2 2 0 0 2 2 2 0 Chorion family 2 APOBEC_C PF05240.14 GAX11675.1 - 0.082 12.9 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 APOBEC-like C-terminal domain NETI PF14044.6 GAX11676.1 - 0.19 11.5 0.3 0.35 10.6 0.3 1.4 1 0 0 1 1 1 0 NETI protein Rhodanese PF00581.20 GAX11677.1 - 1.3e-07 32.1 0.0 2.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 GAX11678.1 - 4e-06 27.3 0.0 6.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_hydro_72 PF03198.14 GAX11679.1 - 2e-49 168.6 0.0 2.6e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 GAX11679.1 - 0.0071 15.8 0.0 0.061 12.7 0.0 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) AvrM-A PF18241.1 GAX11680.1 - 0.25 11.8 6.2 1.8 9.0 2.0 2.5 2 1 0 2 2 2 0 Flax-rust effector AvrM-A Zn_ribbon_17 PF17120.5 GAX11681.1 - 1.1e-12 47.3 10.4 1.1e-12 47.3 10.4 3.1 4 0 0 4 4 4 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 GAX11681.1 - 0.00092 19.4 11.3 0.0031 17.7 11.3 1.9 1 1 0 1 1 1 1 Zinc-ribbon like family DZR PF12773.7 GAX11681.1 - 0.26 11.3 12.1 0.59 10.2 12.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_S28 PF05577.12 GAX11682.1 - 1.3e-56 192.3 0.0 1.6e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 GAX11682.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) TPR_10 PF13374.6 GAX11683.1 - 0.14 12.1 0.3 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PrsW-protease PF13367.6 GAX11684.1 - 2.5e-09 36.9 1.1 2.5e-09 36.9 1.1 2.4 2 0 0 2 2 2 1 PrsW family intramembrane metalloprotease RibD_C PF01872.17 GAX11685.1 - 3.4e-23 82.5 0.0 4.7e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Asp PF00026.23 GAX11686.1 - 1.7e-30 106.5 0.0 5.8e-30 104.8 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAX11686.1 - 3.5e-06 27.4 0.4 0.00028 21.2 0.4 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Mad3_BUB1_I PF08311.12 GAX11687.1 - 1.6e-29 102.4 2.4 3.4e-29 101.3 2.4 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 GAX11687.1 - 5.6e-08 32.5 0.1 1.1e-06 28.2 0.1 2.3 1 1 0 1 1 1 1 Protein kinase domain Cyclin_N2 PF16500.5 GAX11687.1 - 0.12 13.2 2.5 2.1 9.1 0.2 3.1 2 1 1 3 3 3 0 N-terminal region of cyclin_N Pox_ser-thr_kin PF05445.11 GAX11687.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DnaJ_C PF01556.18 GAX11688.1 - 1.3e-28 99.9 0.0 2.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX11688.1 - 7.6e-17 61.2 0.5 1.9e-16 59.9 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Peptidase_S64 PF08192.11 GAX11688.1 - 0.57 8.6 7.2 0.82 8.1 7.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 GAX11688.1 - 9.6 4.8 5.9 13 4.4 5.9 1.1 1 0 0 1 1 1 0 Presenilin LRR_8 PF13855.6 GAX11689.1 - 1e-19 70.0 8.6 2.4e-07 30.4 0.8 4.3 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GAX11689.1 - 3.4e-15 55.9 14.1 0.00032 21.0 0.7 6.2 2 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX11689.1 - 3.1e-08 33.1 7.0 3.2 8.6 0.0 6.9 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.6 GAX11689.1 - 1.4e-05 24.7 1.3 4.5 7.6 0.0 4.7 4 0 0 4 4 4 3 Leucine Rich repeat Mito_carr PF00153.27 GAX11690.1 - 2.9e-21 75.2 0.1 6.6e-12 45.2 0.1 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein Sas10_Utp3 PF04000.15 GAX11691.1 - 1.6e-09 38.2 1.0 1.6e-09 38.2 1.0 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family PorA PF11271.8 GAX11691.1 - 0.18 11.1 3.1 0.3 10.3 3.1 1.3 1 0 0 1 1 1 0 Porin PorA TPR_1 PF00515.28 GAX11692.1 - 2.6e-22 77.6 8.5 2.1e-05 24.1 0.5 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX11692.1 - 9.5e-14 50.3 9.3 7.6e-06 25.7 0.4 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX11692.1 - 5.6e-12 45.1 1.6 2e-08 33.8 0.0 4.9 5 1 1 6 6 6 1 TPR repeat TPR_14 PF13428.6 GAX11692.1 - 5.3e-08 33.0 0.2 0.19 12.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX11692.1 - 2.4e-06 27.5 6.2 0.027 14.8 0.0 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX11692.1 - 6.2e-06 26.6 0.5 0.58 10.7 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11692.1 - 9.2e-06 25.5 13.0 0.1 12.9 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX11692.1 - 1.5e-05 25.1 3.5 0.27 11.6 0.1 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX11692.1 - 2.2e-05 25.0 0.4 0.0022 18.6 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX11692.1 - 0.00023 21.0 3.1 0.034 14.2 0.0 4.6 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX11692.1 - 0.0039 17.3 0.0 0.055 13.6 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX11692.1 - 0.01 16.4 2.8 5.1 8.0 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAX11692.1 - 0.018 15.1 3.0 5.5 7.0 0.0 3.9 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) FAT PF02259.23 GAX11692.1 - 0.018 14.3 1.9 0.024 13.9 0.3 1.9 1 1 1 2 2 2 0 FAT domain DUF1507 PF07408.11 GAX11692.1 - 0.038 13.9 0.1 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1507) PA28_beta PF02252.18 GAX11692.1 - 0.11 12.1 1.7 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Proteasome activator pa28 beta subunit YtxH PF12732.7 GAX11692.1 - 0.89 10.1 3.5 2.2 8.8 0.2 2.9 3 0 0 3 3 2 0 YtxH-like protein Alkyl_sulf_dimr PF14863.6 GAX11692.1 - 5.3 7.5 8.6 5.4 7.5 0.2 3.5 1 1 2 4 4 4 0 Alkyl sulfatase dimerisation MIT PF04212.18 GAX11692.1 - 8.8 6.5 14.1 1.1 9.4 0.5 4.3 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain MIT PF04212.18 GAX11693.1 - 0.00021 21.3 2.0 0.0069 16.4 0.2 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 GAX11693.1 - 0.022 14.5 0.1 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 THUMP PF02926.17 GAX11693.1 - 0.032 14.3 0.1 0.066 13.3 0.1 1.7 2 0 0 2 2 2 0 THUMP domain TPR_2 PF07719.17 GAX11693.1 - 0.22 11.7 1.4 4.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HNOBA PF07701.14 GAX11694.1 - 1.4e-09 37.7 0.0 1.9e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Heme NO binding associated GED PF02212.18 GAX11694.1 - 0.1 12.8 0.4 0.17 12.1 0.4 1.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain Kelch_6 PF13964.6 GAX11695.1 - 5.6e-18 64.5 5.0 0.00066 19.9 0.1 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 GAX11695.1 - 8.6e-15 54.6 18.8 0.0017 18.6 0.0 5.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 GAX11695.1 - 2.4e-13 49.4 4.1 0.0049 16.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAX11695.1 - 4.4e-11 42.6 6.2 0.0088 16.0 0.3 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAX11695.1 - 0.00077 19.4 4.8 0.32 11.0 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAX11695.1 - 0.0032 17.4 6.4 5.4 7.2 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Cupin_8 PF13621.6 GAX11696.1 - 8.9e-56 189.4 7.4 2.5e-55 188.0 7.4 1.6 1 1 0 1 1 1 1 Cupin-like domain Hjc PF01870.18 GAX11696.1 - 0.058 13.4 0.0 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) Transport_MerF PF11431.8 GAX11697.1 - 1.9 8.4 3.5 2.1 8.3 1.2 2.2 2 0 0 2 2 2 0 Membrane transport protein MerF Fer2 PF00111.27 GAX11699.1 - 7.1e-06 25.9 0.1 2.3e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Na_Ca_ex PF01699.24 GAX11700.1 - 2e-35 122.0 33.5 8.1e-20 71.3 5.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Peptidase_S49 PF01343.18 GAX11701.1 - 2.3e-38 131.5 1.1 5.9e-38 130.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S49 Peptidase_S49_N PF08496.10 GAX11701.1 - 4.3e-21 75.6 0.1 5e-19 68.9 0.0 3.1 3 0 0 3 3 3 1 Peptidase family S49 N-terminal SDH_sah PF01972.16 GAX11701.1 - 0.0053 15.8 0.1 0.01 14.9 0.1 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase SPX PF03105.19 GAX11701.1 - 0.04 13.8 0.3 0.055 13.4 0.3 1.2 1 0 0 1 1 1 0 SPX domain ArlS_N PF18719.1 GAX11701.1 - 0.27 11.5 3.7 1.7 8.9 1.2 2.4 2 0 0 2 2 2 0 ArlS sensor domain Pkinase_Tyr PF07714.17 GAX11702.1 - 6.8e-20 71.4 0.0 1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX11702.1 - 8.7e-16 58.1 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FAD_binding_3 PF01494.19 GAX11703.1 - 4.3e-20 72.2 0.0 6.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAX11703.1 - 9.9e-06 25.0 0.0 5.3e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX11703.1 - 1.3e-05 25.0 0.1 0.13 11.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX11703.1 - 1.6e-05 25.0 0.2 4.2e-05 23.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX11703.1 - 0.00031 20.0 0.1 0.047 12.8 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 GAX11703.1 - 0.00041 19.2 0.1 0.0012 17.7 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 GAX11703.1 - 0.0052 15.9 0.1 0.0089 15.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAX11703.1 - 0.035 13.4 0.1 0.52 9.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAX11703.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 GAX11703.1 - 0.08 12.9 0.2 0.3 11.1 0.2 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 GAX11703.1 - 0.1 11.9 0.0 5.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SMK-1 PF04802.15 GAX11704.1 - 2e-40 138.6 0.0 2.5e-39 135.1 0.0 2.4 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 UQ_con PF00179.26 GAX11705.1 - 6e-39 132.9 0.0 6.7e-39 132.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX11705.1 - 0.0014 18.9 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain Acyl_transf_3 PF01757.22 GAX11709.1 - 1.6e-19 70.2 40.5 1.6e-19 70.2 40.5 2.0 2 0 0 2 2 2 1 Acyltransferase family Nop52 PF05997.12 GAX11710.1 - 0.08 12.7 3.9 2.8 7.7 0.4 2.3 1 1 1 2 2 2 0 Nucleolar protein,Nop52 ABC_tran_CTD PF16326.5 GAX11710.1 - 0.15 12.3 16.8 2.1 8.7 9.7 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain YabA PF06156.13 GAX11710.1 - 0.35 11.5 12.1 0.091 13.4 1.3 2.8 1 1 2 3 3 3 0 Initiation control protein YabA DUF5320 PF17253.2 GAX11710.1 - 0.76 10.9 6.0 2.7 9.1 0.4 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5320) PEP-utilisers_N PF05524.13 GAX11710.1 - 0.82 9.9 8.6 6.7 6.9 8.5 2.2 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Syntaxin-6_N PF09177.11 GAX11710.1 - 1.1 9.9 6.6 0.52 10.9 2.5 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal LMBR1 PF04791.16 GAX11710.1 - 1.7 7.4 7.3 1.9 7.3 7.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1993 PF09351.10 GAX11710.1 - 3.2 7.9 5.2 2.6 8.1 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Phage_GPO PF05929.11 GAX11710.1 - 7.2 6.2 11.5 2.2 7.8 7.3 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_Mu_Gam PF07352.12 GAX11710.1 - 9.6 6.1 20.3 0.039 13.9 3.3 3.3 1 1 1 3 3 3 0 Bacteriophage Mu Gam like protein Pkinase PF00069.25 GAX11711.1 - 2.8e-80 269.5 0.0 4.2e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11711.1 - 3.5e-38 131.4 0.2 5.4e-38 130.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 GAX11711.1 - 0.0001 21.7 0.2 0.0003 20.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX11711.1 - 0.00063 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX11711.1 - 0.079 12.9 0.0 1.2 9.0 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF2135 PF09906.9 GAX11711.1 - 0.13 12.6 0.1 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) Hydrolase_4 PF12146.8 GAX11712.1 - 7.4e-08 31.9 0.0 3.1e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX11712.1 - 0.044 13.4 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PseudoU_synth_2 PF00849.22 GAX11713.1 - 5.7e-23 81.8 0.0 1.6e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 RNA pseudouridylate synthase UPF0176_N PF17773.1 GAX11713.1 - 1.9e-15 57.0 0.0 5e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAX11713.1 - 7.8e-12 45.4 11.2 7.8e-12 45.4 11.2 3.1 3 0 0 3 3 3 1 Rhodanase C-terminal Rhodanese PF00581.20 GAX11713.1 - 1.4e-07 32.0 0.1 3.6e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF932 PF06067.11 GAX11713.1 - 0.1 12.4 1.9 0.19 11.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF932) UBX PF00789.20 GAX11714.1 - 5.1e-10 39.4 0.1 3.2e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 UBX domain CENP-L PF13092.6 GAX11714.1 - 0.077 13.2 0.4 0.077 13.2 0.4 2.5 2 1 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 CemA PF03040.14 GAX11714.1 - 1.5 8.7 7.3 2.2 8.2 5.3 2.0 2 0 0 2 2 2 0 CemA family Spore_coat_CotO PF14153.6 GAX11714.1 - 7.4 6.5 16.2 0.39 10.6 5.0 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DUF572 PF04502.13 GAX11714.1 - 8.4 5.9 11.4 2 8.0 7.6 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) CPBP PF02517.16 GAX11716.1 - 7.7e-12 45.4 17.8 2.9e-11 43.6 17.7 2.2 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease Bee_toxin PF17454.2 GAX11716.1 - 0.11 12.6 1.5 0.21 11.7 1.5 1.4 1 0 0 1 1 1 0 Honey bee toxin adh_short PF00106.25 GAX11718.1 - 1.1e-35 122.9 0.2 2.3e-29 102.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX11718.1 - 4.9e-22 78.6 0.0 2.8e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX11718.1 - 2.1e-10 40.8 0.1 3.3e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 GAX11718.1 - 4.1e-05 23.8 0.3 6.8e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAX11718.1 - 0.00056 19.5 0.2 0.0009 18.8 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sterol_MT_C PF08498.10 GAX11719.1 - 4.2e-21 75.0 0.1 7.5e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAX11719.1 - 1.7e-16 60.7 0.0 2.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX11719.1 - 1.3e-14 54.7 0.0 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX11719.1 - 2.2e-13 50.3 0.0 3.1e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX11719.1 - 7.9e-11 42.1 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX11719.1 - 4.6e-10 39.2 0.0 5.8e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 GAX11719.1 - 7.4e-08 33.0 0.0 2.6e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX11719.1 - 1e-06 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 GAX11719.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 GAX11719.1 - 0.06 12.3 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 GAX11719.1 - 0.062 13.3 0.1 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.27 GAX11720.1 - 3.4e-40 135.9 4.8 2e-13 50.1 0.2 4.2 3 2 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.21 GAX11721.1 - 9e-07 28.4 0.2 0.00035 19.9 0.2 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family ubiquitin PF00240.23 GAX11723.1 - 1.3e-09 37.6 0.2 6.4e-09 35.4 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin family UBA PF00627.31 GAX11723.1 - 1.6e-06 27.9 2.1 2.1e-06 27.5 0.2 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 GAX11723.1 - 6.1e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 GAX11723.1 - 0.00019 21.1 51.2 0.0018 18.0 12.6 4.8 2 2 2 4 4 4 3 XPC-binding domain Rad60-SLD PF11976.8 GAX11723.1 - 0.0091 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAX11723.1 - 0.061 13.9 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CUE PF02845.16 GAX11723.1 - 0.091 12.5 1.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 0 CUE domain GlnE PF03710.15 GAX11723.1 - 0.8 9.1 7.5 0.9 8.9 2.0 2.4 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase BSD PF03909.17 GAX11723.1 - 1.8 8.6 6.6 13 5.8 0.3 4.3 2 2 2 4 4 4 0 BSD domain STI1 PF17830.1 GAX11723.1 - 2.7 8.0 58.2 0.052 13.5 9.3 4.8 2 2 2 4 4 4 0 STI1 domain Bep_C_terminal PF17841.1 GAX11723.1 - 4.5 7.6 6.8 18 5.6 0.2 3.5 2 1 1 3 3 3 0 BID domain of Bartonella effector protein (Bep) TUDOR_5 PF18359.1 GAX11724.1 - 0.00077 19.1 0.4 0.002 17.8 0.0 1.9 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 GAX11724.1 - 0.012 15.6 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 GAX11724.1 - 0.051 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor zf-CXXC PF02008.20 GAX11724.1 - 0.85 9.7 102.4 0.17 12.0 11.5 5.6 5 0 0 5 5 5 0 CXXC zinc finger domain Thioredoxin_8 PF13905.6 GAX11725.1 - 1.7e-20 73.1 0.0 3.3e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DUF5623 PF18536.1 GAX11725.1 - 0.35 11.1 4.4 0.63 10.3 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) FG-GAP_2 PF14312.6 GAX11726.1 - 2.9e-10 40.2 17.0 0.0033 17.6 0.3 5.6 5 0 0 5 5 5 4 FG-GAP repeat FlpD PF02662.16 GAX11726.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit FG-GAP_2 PF14312.6 GAX11727.1 - 5.7e-10 39.3 15.7 0.00077 19.7 0.3 5.3 5 0 0 5 5 5 4 FG-GAP repeat zf-RING_2 PF13639.6 GAX11728.1 - 1.3e-11 44.7 10.4 3.1e-11 43.4 10.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX11728.1 - 1.7e-08 34.1 6.5 5.1e-08 32.5 6.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX11728.1 - 1.8e-06 27.7 10.2 3.7e-06 26.7 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX11728.1 - 0.00048 20.4 10.7 0.00048 20.4 10.7 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX11728.1 - 0.00093 19.0 9.4 0.0025 17.7 9.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX11728.1 - 0.0023 17.5 8.8 0.0051 16.4 8.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type SAP PF02037.27 GAX11728.1 - 0.008 15.9 2.1 9.4 6.1 0.0 3.8 4 0 0 4 4 4 1 SAP domain zf-C3HC4_3 PF13920.6 GAX11728.1 - 0.0087 15.9 11.1 0.019 14.8 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX11728.1 - 0.011 15.8 3.6 0.023 14.7 3.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Armet PF10208.9 GAX11728.1 - 0.011 15.7 0.1 29 4.6 0.0 3.8 4 0 0 4 4 4 0 Degradation arginine-rich protein for mis-folding zf-RING_UBOX PF13445.6 GAX11728.1 - 0.021 14.8 9.3 0.2 11.7 9.1 2.6 1 1 1 2 2 2 0 RING-type zinc-finger zf_C2H2_10 PF18414.1 GAX11728.1 - 0.048 13.2 3.2 1 8.9 0.5 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger Prok-RING_4 PF14447.6 GAX11728.1 - 0.065 13.1 8.5 0.17 11.8 8.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAX11728.1 - 0.11 12.4 10.9 0.28 11.2 10.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_RING PF05883.11 GAX11728.1 - 0.11 12.4 0.3 0.32 11.0 0.3 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Rho_N PF07498.12 GAX11728.1 - 0.49 10.4 1.5 20 5.2 0.0 3.2 4 0 0 4 4 4 0 Rho termination factor, N-terminal domain GDPD PF03009.17 GAX11729.1 - 2.1e-24 86.7 0.0 1.8e-22 80.3 0.0 2.6 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family DUF3684 PF12449.8 GAX11731.1 - 6.6e-109 365.3 16.4 1.5e-76 258.1 4.1 4.9 2 2 2 4 4 4 4 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 GAX11731.1 - 0.00022 21.1 0.0 0.00065 19.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CUE PF02845.16 GAX11731.1 - 0.09 12.5 0.0 0.33 10.7 0.0 1.9 1 0 0 1 1 1 0 CUE domain Lipase_3 PF01764.25 GAX11733.1 - 3.1e-17 62.8 0.0 1.5e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAX11733.1 - 0.0024 18.5 0.1 0.006 17.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family FlgD PF03963.14 GAX11733.1 - 0.1 12.9 0.3 0.27 11.6 0.3 1.6 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region AAA_23 PF13476.6 GAX11734.1 - 2.9e-22 80.2 4.5 2.9e-22 80.2 4.5 6.8 4 2 2 6 6 6 1 AAA domain SMC_N PF02463.19 GAX11734.1 - 5.4e-17 62.0 52.3 1.3e-15 57.5 52.2 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX11734.1 - 9.9e-14 51.8 17.9 9.9e-14 51.8 17.9 3.5 3 1 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 GAX11734.1 - 7.8e-05 22.3 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ZapB PF06005.12 GAX11734.1 - 0.00081 19.8 2.2 0.00081 19.8 2.2 9.6 3 2 5 8 8 8 1 Cell division protein ZapB AAA_21 PF13304.6 GAX11734.1 - 0.00096 19.0 0.2 0.00096 19.0 0.2 4.0 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF948 PF06103.11 GAX11734.1 - 0.0037 17.5 41.2 0.0056 16.9 0.2 7.6 5 2 1 7 7 7 2 Bacterial protein of unknown function (DUF948) SbcCD_C PF13558.6 GAX11734.1 - 0.012 15.8 0.0 0.063 13.5 0.0 2.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Laminin_II PF06009.12 GAX11734.1 - 3.5 7.6 72.9 0.051 13.6 1.6 7.3 4 2 4 8 8 8 0 Laminin Domain II Pkinase PF00069.25 GAX11735.1 - 2.1e-132 440.4 0.0 2.8e-67 226.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11735.1 - 1.5e-58 198.1 0.0 6e-29 101.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX11735.1 - 4.6e-14 52.0 0.0 2.1e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 GAX11735.1 - 1.8e-09 37.3 0.1 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX11735.1 - 5.1e-09 35.8 0.0 0.00033 20.1 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 GAX11735.1 - 2e-07 31.2 0.2 0.54 10.1 0.2 4.2 2 2 2 4 4 4 3 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAX11735.1 - 0.054 13.0 0.1 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 GAX11735.1 - 0.091 11.7 0.2 4.7 6.1 0.1 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase NOA36 PF06524.12 GAX11736.1 - 1.4 8.2 8.1 2.8 7.2 8.1 1.5 1 0 0 1 1 1 0 NOA36 protein CtaG_Cox11 PF04442.14 GAX11737.1 - 3.4e-56 189.5 0.1 3.5e-55 186.2 0.1 2.0 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 OSCP PF00213.18 GAX11738.1 - 2e-42 145.2 0.7 2.4e-42 145.0 0.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Pam16 PF03656.13 GAX11740.1 - 2.4e-20 72.8 2.6 3.3e-20 72.4 2.6 1.2 1 0 0 1 1 1 1 Pam16 Phage_holin_Dp1 PF16938.5 GAX11740.1 - 0.018 15.2 0.3 0.028 14.6 0.3 1.3 1 0 0 1 1 1 0 Putative phage holin Dp-1 IncD PF17628.2 GAX11740.1 - 0.025 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D Pkinase PF00069.25 GAX11741.1 - 1.3e-74 250.9 0.0 1.6e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11741.1 - 1.8e-35 122.5 0.0 2.3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX11741.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mem_trans PF03547.18 GAX11742.1 - 3.3e-12 45.5 20.3 3.4e-10 38.9 20.3 2.7 1 1 0 1 1 1 1 Membrane transport protein FH2 PF02181.23 GAX11743.1 - 7.9e-61 206.2 2.8 7.9e-61 206.2 2.8 3.5 4 1 1 5 5 5 2 Formin Homology 2 Domain CCDC53 PF10152.9 GAX11743.1 - 2.8e-08 34.3 15.3 8.8e-05 23.0 1.3 9.5 9 3 1 10 10 10 4 Subunit CCDC53 of WASH complex Retrotran_gag_2 PF14223.6 GAX11743.1 - 0.012 15.3 0.1 0.041 13.5 0.1 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Sigma70_r4 PF04545.16 GAX11743.1 - 0.08 12.5 0.5 0.45 10.1 0.5 2.5 1 0 0 1 1 1 0 Sigma-70, region 4 HVSL PF09749.9 GAX11744.1 - 2.4e-34 118.9 0.0 3.2e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 GAX11744.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily YL1 PF05764.13 GAX11746.1 - 4e-25 89.4 8.3 4e-25 89.4 8.3 2.1 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 GAX11746.1 - 2.2e-14 52.9 0.2 5.7e-14 51.6 0.2 1.8 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MRP-S34 PF16053.5 GAX11746.1 - 0.053 13.2 0.4 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S34 SPX PF03105.19 GAX11747.1 - 3.1e-18 66.9 9.8 3.8e-10 40.2 0.3 3.3 2 1 1 3 3 3 2 SPX domain ORC6 PF05460.13 GAX11747.1 - 0.051 12.9 1.0 0.079 12.2 1.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DEAD PF00270.29 GAX11749.1 - 2.3e-47 161.0 0.0 1.2e-46 158.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX11749.1 - 7.7e-31 106.7 0.0 1.4e-28 99.4 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX11749.1 - 0.0011 19.0 0.1 0.021 14.8 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HARE-HTH PF05066.13 GAX11749.1 - 0.0074 16.7 0.2 0.044 14.2 0.2 2.4 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain DUF3240 PF11582.8 GAX11749.1 - 0.032 14.4 0.3 0.087 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) HTH_8 PF02954.19 GAX11749.1 - 0.089 12.6 0.6 5.9 6.8 0.1 2.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family AAA_22 PF13401.6 GAX11749.1 - 0.44 10.8 2.8 1.9 8.8 0.4 3.0 3 1 0 3 3 3 0 AAA domain TSP_NTD PF17804.1 GAX11749.1 - 2.4 8.4 6.0 1.2 9.3 3.5 1.7 2 0 0 2 2 2 0 Tail specific protease N-terminal domain GCP_C_terminal PF04130.13 GAX11750.1 - 5.2e-55 187.1 4.7 5.2e-55 187.1 4.7 1.4 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAX11750.1 - 1.5e-47 162.8 0.0 2.4e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal FKBP_N_2 PF18023.1 GAX11750.1 - 0.11 12.5 0.3 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 BDBT FKBP like N-terminal L1R_F9L PF02442.17 GAX11751.1 - 0.00099 19.0 0.1 0.0049 16.7 0.0 2.0 2 0 0 2 2 2 1 Lipid membrane protein of large eukaryotic DNA viruses THOC7 PF05615.13 GAX11751.1 - 0.0012 19.1 5.6 0.19 12.0 0.5 2.6 2 0 0 2 2 2 2 Tho complex subunit 7 RasGAP_C PF03836.15 GAX11751.1 - 0.0033 17.6 1.0 0.0033 17.6 1.0 2.5 2 0 0 2 2 2 1 RasGAP C-terminus DUF327 PF03885.13 GAX11751.1 - 0.011 15.6 0.5 0.031 14.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF327) OmpH PF03938.14 GAX11751.1 - 1.6 9.1 6.7 0.55 10.6 0.9 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 GAX11751.1 - 2 8.4 11.0 7.3 6.7 2.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 GAX11751.1 - 3.6 7.7 14.9 0.24 11.5 3.4 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 GAX11751.1 - 4.4 6.1 13.8 1.6 7.6 2.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4600 PF15372.6 GAX11751.1 - 6.2 7.3 13.0 0.34 11.4 3.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Lzipper-MIP1 PF14389.6 GAX11751.1 - 9.8 6.6 13.9 0.023 15.0 2.7 2.5 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Radical_SAM PF04055.21 GAX11752.1 - 7.7e-30 104.5 0.0 1.4e-29 103.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 GAX11752.1 - 1.4e-27 95.6 0.1 3.1e-27 94.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 GAX11752.1 - 1.6e-09 37.6 0.1 3.6e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 TRAM domain Rotamase_3 PF13616.6 GAX11752.1 - 0.00049 20.6 0.0 0.013 16.0 0.0 2.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 GAX11752.1 - 0.00078 20.4 0.0 0.0076 17.2 0.0 2.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain TRAM_2 PF18693.1 GAX11752.1 - 0.0064 16.6 0.3 0.21 11.8 0.1 3.0 2 1 0 2 2 2 1 TRAM domain Myb_DNA-binding PF00249.31 GAX11753.1 - 5.2e-11 42.6 0.0 7.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX11753.1 - 0.023 14.6 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Replic_Relax PF13814.6 GAX11753.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation Mg-por_mtran_C PF07109.11 GAX11754.1 - 1e-35 122.0 0.2 1.5e-34 118.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 GAX11754.1 - 3.9e-14 53.1 0.1 8.8e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX11754.1 - 2.2e-11 43.8 0.3 4.2e-11 42.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX11754.1 - 1e-08 35.8 0.0 2.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX11754.1 - 4.7e-08 33.0 0.1 1e-07 32.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX11754.1 - 6.3e-08 33.2 0.1 1.5e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX11754.1 - 2.1e-07 30.7 0.2 3.7e-07 29.8 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX11754.1 - 2.1e-06 27.4 0.1 3.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 GAX11754.1 - 3e-06 26.8 0.2 8.9e-06 25.2 0.1 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 GAX11754.1 - 3.4e-06 27.1 0.3 0.00032 20.7 0.1 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX11754.1 - 4.4e-05 23.5 0.3 0.00011 22.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GAX11754.1 - 0.00024 20.5 0.0 0.00047 19.5 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 GAX11754.1 - 0.00043 19.9 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Cons_hypoth95 PF03602.15 GAX11754.1 - 0.00046 19.9 0.1 0.00084 19.0 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 GAX11754.1 - 0.00046 19.7 0.0 0.00097 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.15 GAX11754.1 - 0.029 13.7 0.1 0.076 12.3 0.0 1.7 2 1 0 2 2 2 0 rRNA small subunit methyltransferase G tRNA_U5-meth_tr PF05958.11 GAX11754.1 - 0.038 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF1307 PF06998.11 GAX11754.1 - 0.059 13.4 0.6 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1307) DOT1 PF08123.13 GAX11754.1 - 0.078 12.5 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 Histone methylation protein DOT1 Mito_carr PF00153.27 GAX11756.1 - 2.1e-60 200.7 2.9 2.6e-19 68.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 GAX11756.1 - 0.023 14.8 0.0 25 5.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) Methyltransf_8 PF05148.15 GAX11757.1 - 1.3e-75 254.0 0.2 1.8e-75 253.6 0.2 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 GAX11757.1 - 1.9e-07 31.6 0.1 9.4e-07 29.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX11757.1 - 9.2e-07 29.5 0.1 7.6e-05 23.3 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX11757.1 - 4.3e-06 26.6 0.1 0.0014 18.4 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX11757.1 - 6.1e-05 22.5 0.1 0.011 15.0 0.0 2.3 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Bmt2 PF11968.8 GAX11757.1 - 0.022 14.6 0.1 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_32 PF13679.6 GAX11757.1 - 0.078 13.0 0.0 0.078 13.0 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX11757.1 - 0.15 12.8 0.0 7 7.5 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain DUF601 PF04642.12 GAX11757.1 - 9.3 5.6 17.2 17 4.8 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 WD40 PF00400.32 GAX11758.1 - 3e-28 97.5 9.0 1.7e-06 28.7 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX11758.1 - 1.9e-13 50.5 0.1 0.01 16.1 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Thioredoxin PF00085.20 GAX11761.1 - 5.7e-08 32.7 0.0 7.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin zf-nanos PF05741.13 GAX11761.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nanos RNA binding domain Met_10 PF02475.16 GAX11762.1 - 7.1e-52 176.1 0.2 2e-51 174.6 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein TRM PF02005.16 GAX11762.1 - 0.0033 16.7 0.6 0.0033 16.7 0.6 2.0 2 1 1 3 3 3 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltr_RsmB-F PF01189.17 GAX11762.1 - 0.051 13.2 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F MTS PF05175.14 GAX11762.1 - 0.059 12.9 0.5 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase small domain BUD22 PF09073.10 GAX11763.1 - 0.41 9.9 7.1 0.66 9.3 7.1 1.3 1 0 0 1 1 1 0 BUD22 THEG PF14912.6 GAX11764.1 - 0.12 12.8 0.0 0.45 11.0 0.0 1.9 1 0 0 1 1 1 0 Testicular haploid expressed repeat Fer4 PF00037.27 GAX11764.1 - 2 8.3 4.2 17 5.4 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Exo_endo_phos PF03372.23 GAX11765.1 - 0.099 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PAS_9 PF13426.7 GAX11767.1 - 1e-19 70.7 0.1 3.6e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 PAS domain bZIP_2 PF07716.15 GAX11767.1 - 5.8e-08 32.7 12.6 1.3e-07 31.6 12.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PAS_3 PF08447.12 GAX11767.1 - 1.3e-07 31.8 0.0 2.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold bZIP_1 PF00170.21 GAX11767.1 - 2.9e-07 30.5 11.6 5.7e-07 29.5 11.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.25 GAX11767.1 - 1.4e-05 25.0 0.0 3.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 GAX11767.1 - 0.00022 21.2 0.0 0.25 11.4 0.0 3.3 4 1 0 4 4 4 2 PAS domain PAS_4 PF08448.10 GAX11767.1 - 0.0016 18.7 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold HAP1_N PF04849.13 GAX11767.1 - 0.017 14.3 7.1 0.025 13.8 7.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1840 PF08895.11 GAX11767.1 - 0.16 12.3 2.2 0.4 11.0 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) Cofilin_ADF PF00241.20 GAX11768.1 - 2.4e-36 124.2 0.0 2.8e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ORMDL PF04061.14 GAX11769.1 - 1.5e-25 89.6 4.5 2.1e-25 89.1 4.5 1.2 1 0 0 1 1 1 1 ORMDL family Cyt_bd_oxida_II PF02322.15 GAX11769.1 - 0.0062 15.9 2.4 0.009 15.4 2.4 1.2 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II UAA PF08449.11 GAX11770.1 - 3.5e-55 187.4 16.6 4e-55 187.2 16.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX11770.1 - 0.00011 22.3 23.3 0.031 14.4 10.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAX11770.1 - 0.00055 19.4 12.4 0.001 18.5 12.4 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 GAX11770.1 - 0.00093 18.2 1.6 0.00093 18.2 1.6 2.1 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like SpoIIIAH PF12685.7 GAX11772.1 - 0.0027 17.6 1.3 0.0049 16.7 1.3 1.4 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF2076 PF09849.9 GAX11772.1 - 0.17 11.9 11.9 0.25 11.4 11.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PPP4R2 PF09184.11 GAX11772.1 - 0.22 11.1 10.0 0.36 10.4 10.0 1.4 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 GAX11772.1 - 1.2 8.4 13.4 1.5 8.0 13.4 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 GAX11772.1 - 5.6 6.8 17.3 7.3 6.5 17.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 GAX11772.1 - 8.9 6.0 23.0 16 5.1 23.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DENN PF02141.21 GAX11774.1 - 1.4e-34 119.7 1.5 2.5e-34 118.9 1.5 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain WD40 PF00400.32 GAX11774.1 - 8.7e-14 51.7 30.1 1.8e-05 25.4 1.0 7.6 8 0 0 8 8 8 3 WD domain, G-beta repeat SBF2 PF12335.8 GAX11774.1 - 0.0015 18.2 0.0 0.0015 18.2 0.0 1.8 2 0 0 2 2 2 1 Myotubularin protein uDENN PF03456.18 GAX11774.1 - 0.004 17.9 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 GAX11774.1 - 0.022 14.7 0.4 0.085 12.9 0.4 2.1 1 0 0 1 1 1 0 dDENN domain zf-RING_2 PF13639.6 GAX11775.1 - 6.7e-09 35.9 10.4 6.7e-09 35.9 10.4 2.1 2 1 0 2 2 1 1 Ring finger domain zf-ANAPC11 PF12861.7 GAX11775.1 - 6.7e-06 26.1 9.5 5.3e-05 23.2 9.6 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAX11775.1 - 8.7e-06 25.5 10.5 3.2e-05 23.7 10.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.17 GAX11775.1 - 3.7e-05 23.3 0.5 8.8e-05 22.1 0.5 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-C3HC4 PF00097.25 GAX11775.1 - 0.0001 22.1 10.5 0.00032 20.5 10.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAX11775.1 - 0.0012 18.9 5.8 0.0062 16.7 5.8 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAX11775.1 - 0.0013 19.0 15.4 0.0063 16.8 15.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAX11775.1 - 0.0046 16.8 6.7 0.012 15.4 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GAX11775.1 - 0.0062 16.3 8.0 0.014 15.2 8.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 GAX11775.1 - 0.0074 16.3 9.0 0.022 14.8 9.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 GAX11775.1 - 0.01 16.0 10.2 0.01 16.0 10.2 2.7 2 1 1 3 3 3 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 GAX11775.1 - 0.031 14.2 4.2 0.031 14.2 4.2 2.4 2 1 0 3 3 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 GAX11775.1 - 0.05 13.7 9.7 0.15 12.2 9.7 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING_11 PF17123.5 GAX11775.1 - 0.1 12.4 4.6 0.28 11.0 4.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING-like PF08746.11 GAX11775.1 - 0.74 10.2 18.3 0.23 11.8 13.8 2.6 2 1 1 3 3 3 0 RING-like domain zf-RING_5 PF14634.6 GAX11775.1 - 4.9 7.2 14.7 0.69 9.9 10.1 2.0 2 0 0 2 2 2 0 zinc-RING finger domain LRR_6 PF13516.6 GAX11776.1 - 0.22 11.7 1.6 0.61 10.3 1.6 1.8 1 0 0 1 1 1 0 Leucine Rich repeat NAD_binding_4 PF07993.12 GAX11777.1 - 1.1e-38 132.9 0.0 3.6e-38 131.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 GAX11777.1 - 0.00036 20.1 0.0 0.0072 15.8 0.0 2.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF5446 PF17522.2 GAX11777.1 - 0.11 12.7 0.0 27 5.0 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5446) DUF512 PF04459.12 GAX11777.1 - 0.16 11.2 0.0 0.59 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF512) DEAD PF00270.29 GAX11778.1 - 1.8e-35 122.3 0.0 2.9e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX11778.1 - 2.7e-25 88.9 0.0 5e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX11778.1 - 2.3e-05 24.5 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX11778.1 - 0.0024 18.2 0.0 0.0067 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain TMF_TATA_bd PF12325.8 GAX11780.1 - 0.00014 22.1 18.8 1 9.6 6.6 3.7 2 1 1 3 3 3 2 TATA element modulatory factor 1 TATA binding AIP3 PF03915.13 GAX11780.1 - 0.00038 19.7 16.2 0.004 16.3 16.2 2.1 1 1 0 1 1 1 1 Actin interacting protein 3 ZapB PF06005.12 GAX11780.1 - 0.0017 18.8 16.0 3.7 8.1 0.0 4.7 4 0 0 4 4 4 0 Cell division protein ZapB Cnn_1N PF07989.11 GAX11780.1 - 0.009 16.1 11.0 1 9.6 2.3 4.4 1 1 3 4 4 4 2 Centrosomin N-terminal motif 1 DivIC PF04977.15 GAX11780.1 - 0.011 15.4 10.6 1.7 8.5 0.6 4.3 3 1 1 4 4 4 0 Septum formation initiator Phage_GP20 PF06810.11 GAX11780.1 - 0.019 14.8 14.6 0.043 13.6 0.8 3.4 1 1 1 3 3 3 0 Phage minor structural protein GP20 ATG16 PF08614.11 GAX11780.1 - 0.02 15.1 23.3 0.2 11.8 8.6 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FlxA PF14282.6 GAX11780.1 - 0.02 14.9 18.1 0.1 12.6 1.0 3.9 2 2 2 4 4 4 0 FlxA-like protein Golgin_A5 PF09787.9 GAX11780.1 - 0.024 14.1 18.7 0.066 12.7 6.0 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 GAX11780.1 - 0.025 14.6 23.2 0.63 10.1 1.8 4.4 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 GAX11780.1 - 0.032 14.4 13.4 0.34 11.2 5.7 3.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SUN PF03856.13 GAX11780.1 - 0.032 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) PRKG1_interact PF15898.5 GAX11780.1 - 0.037 14.9 8.6 0.037 14.9 8.6 4.2 3 2 2 5 5 3 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 GAX11780.1 - 0.047 13.0 15.6 1.1 8.5 15.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C4H2 PF10146.9 GAX11780.1 - 0.047 14.0 12.5 0.42 10.9 6.1 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein HlyD_2 PF12700.7 GAX11780.1 - 0.066 11.9 2.8 0.13 11.0 2.8 1.4 1 0 0 1 1 1 0 HlyD family secretion protein SOGA PF11365.8 GAX11780.1 - 0.086 14.0 14.3 0.13 13.4 4.7 3.6 2 2 1 3 3 3 0 Protein SOGA EHN PF06441.12 GAX11780.1 - 0.088 13.2 1.3 0.63 10.4 0.1 2.8 2 1 0 2 2 2 0 Epoxide hydrolase N terminus HR1 PF02185.16 GAX11780.1 - 0.098 12.8 14.6 5.8 7.1 1.1 4.8 3 2 0 3 3 3 0 Hr1 repeat Pox_A_type_inc PF04508.12 GAX11780.1 - 0.15 12.0 9.3 28 4.8 0.0 5.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat IL2 PF00715.17 GAX11780.1 - 0.15 12.0 4.0 0.21 11.5 0.7 2.8 2 1 1 3 3 2 0 Interleukin 2 APG6_N PF17675.1 GAX11780.1 - 0.17 12.4 20.8 0.13 12.8 5.7 3.2 2 1 1 3 3 2 0 Apg6 coiled-coil region DASH_Dad2 PF08654.10 GAX11780.1 - 0.19 12.1 0.3 0.19 12.1 0.3 3.4 3 1 0 4 4 2 0 DASH complex subunit Dad2 TMPIT PF07851.13 GAX11780.1 - 0.25 10.6 10.7 0.43 9.8 0.3 2.6 3 0 0 3 3 2 0 TMPIT-like protein FapA PF03961.13 GAX11780.1 - 0.27 9.8 14.5 0.013 14.2 6.2 2.4 1 1 2 3 3 3 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 GAX11780.1 - 0.28 11.6 23.6 0.45 10.9 10.1 3.3 1 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region betaPIX_CC PF16523.5 GAX11780.1 - 0.28 11.0 5.6 0.35 10.7 0.3 3.2 2 1 1 3 3 2 0 betaPIX coiled coil FlaC_arch PF05377.11 GAX11780.1 - 0.39 11.1 12.7 3.4 8.1 1.0 4.3 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF1640 PF07798.11 GAX11780.1 - 0.39 10.7 17.5 0.38 10.8 5.4 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) Tup_N PF08581.10 GAX11780.1 - 0.53 10.6 11.3 8 6.8 2.9 4.5 3 1 1 4 4 4 0 Tup N-terminal FAP206 PF12018.8 GAX11780.1 - 0.54 9.7 8.6 1.8 8.0 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF4618 PF15397.6 GAX11780.1 - 0.55 9.6 17.2 1.1 8.6 6.5 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Fzo_mitofusin PF04799.13 GAX11780.1 - 0.61 9.6 11.2 1.3 8.5 2.2 2.8 2 1 1 3 3 3 0 fzo-like conserved region YscO PF07321.12 GAX11780.1 - 0.72 9.8 16.4 3.7 7.5 6.9 3.7 3 1 0 3 3 3 0 Type III secretion protein YscO Occludin_ELL PF07303.13 GAX11780.1 - 0.8 10.5 0.1 0.8 10.5 0.1 4.6 2 1 3 5 5 5 0 Occludin homology domain DUF2203 PF09969.9 GAX11780.1 - 0.82 10.4 11.5 0.7 10.6 1.1 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HIP1_clath_bdg PF16515.5 GAX11780.1 - 0.89 10.2 19.7 8.8 7.0 4.1 4.3 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 GAX11780.1 - 0.94 9.9 22.6 4.6 7.6 15.7 2.6 1 1 1 2 2 2 0 Fez1 Csm1_N PF18504.1 GAX11780.1 - 1 9.7 13.0 17 5.8 0.8 5.1 2 1 3 5 5 5 0 Csm1 N-terminal domain Phage_GPO PF05929.11 GAX11780.1 - 1.5 8.4 10.6 4.3 6.9 0.4 2.3 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase WDCP PF15390.6 GAX11780.1 - 1.6 7.0 10.4 2.8 6.2 10.4 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3972 PF13118.6 GAX11780.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3972) WD40_alt PF14077.6 GAX11780.1 - 1.9 8.4 5.5 28 4.7 0.6 3.9 3 1 1 4 4 4 0 Alternative WD40 repeat motif BLOC1_2 PF10046.9 GAX11780.1 - 2 8.8 11.7 3.6 7.9 0.9 3.8 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lzipper-MIP1 PF14389.6 GAX11780.1 - 2 8.8 15.0 0.071 13.4 4.6 3.4 3 1 1 4 4 3 0 Leucine-zipper of ternary complex factor MIP1 T2SSM PF04612.12 GAX11780.1 - 2.1 8.4 8.6 0.37 10.8 0.2 2.9 1 1 1 3 3 3 0 Type II secretion system (T2SS), protein M FAM184 PF15665.5 GAX11780.1 - 2.7 7.7 21.4 0.27 11.0 6.8 3.0 2 1 2 4 4 4 0 Family with sequence similarity 184, A and B bZIP_1 PF00170.21 GAX11780.1 - 2.9 8.1 15.5 4.1 7.6 1.6 4.8 4 1 0 4 4 4 0 bZIP transcription factor DUF1664 PF07889.12 GAX11780.1 - 3 7.9 11.2 4.6 7.3 1.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 GAX11780.1 - 3.2 7.8 14.4 4.1 7.4 0.7 4.4 4 0 0 4 4 4 0 Prefoldin subunit YabA PF06156.13 GAX11780.1 - 3.5 8.3 14.6 6.2 7.5 1.1 4.1 1 1 2 3 3 3 0 Initiation control protein YabA Uds1 PF15456.6 GAX11780.1 - 4.8 7.4 17.9 1.1 9.4 9.5 3.4 3 2 0 3 3 2 0 Up-regulated During Septation Rop-like PF05082.13 GAX11780.1 - 5.3 6.9 7.5 3.6 7.5 0.7 3.5 3 1 1 4 4 3 0 Rop-like FUSC PF04632.12 GAX11780.1 - 5.7 5.3 8.1 25 3.2 8.1 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.8 GAX11780.1 - 6.2 6.9 22.6 0.83 9.7 0.1 4.8 2 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding PAP_fibrillin PF04755.12 GAX11781.1 - 4.4e-05 23.5 2.3 0.016 15.1 0.1 2.1 2 0 0 2 2 2 2 PAP_fibrillin Cpn60_TCP1 PF00118.24 GAX11782.1 - 4e-138 461.1 5.9 4.5e-138 460.9 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ChiW_Ig_like PF18683.1 GAX11782.1 - 0.08 13.2 1.2 0.19 11.9 1.2 1.6 1 0 0 1 1 1 0 Chitinase W immunoglobulin-like domain 7tm_3 PF00003.22 GAX11783.1 - 2.6e-37 128.8 11.4 3.6e-37 128.4 11.4 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX11783.1 - 9.4e-35 120.4 0.0 1.3e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain SUFU_C PF12470.8 GAX11783.1 - 0.2 11.7 1.8 0.36 10.9 1.8 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain VirB3 PF05101.13 GAX11783.1 - 7.8 6.8 7.9 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein 7tm_3 PF00003.22 GAX11784.1 - 1.3e-36 126.5 11.7 1.8e-36 126.1 11.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX11784.1 - 2.1e-35 122.5 0.0 3.2e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain FAD_binding_3 PF01494.19 GAX11785.1 - 3.1e-12 46.4 0.0 1.3e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAX11785.1 - 0.0016 18.1 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX11785.1 - 0.0026 18.3 0.1 0.0045 17.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAX11785.1 - 0.0055 16.0 0.1 0.0096 15.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX11785.1 - 0.019 15.2 0.1 0.044 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX11785.1 - 0.078 12.0 0.7 0.12 11.5 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAX11785.1 - 0.26 9.9 0.2 0.4 9.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Trypsin PF00089.26 GAX11787.1 - 8.3e-50 169.6 0.0 1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX11787.1 - 0.00091 20.1 0.1 0.0029 18.5 0.1 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain PT PF04886.12 GAX11787.1 - 0.0067 16.0 3.2 0.0067 16.0 3.2 3.6 1 1 2 3 3 3 3 PT repeat Helicase_C PF00271.31 GAX11788.1 - 2.5e-17 63.2 0.2 3.3e-16 59.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX11788.1 - 1.1e-16 61.1 0.0 9.1e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase CarD_CdnL_TRCF PF02559.16 GAX11788.1 - 5e-15 56.0 0.0 2.9e-14 53.5 0.0 2.4 1 1 0 1 1 1 1 CarD-like/TRCF domain ResIII PF04851.15 GAX11788.1 - 0.00012 22.2 0.1 0.00042 20.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1542 PF07564.11 GAX11788.1 - 0.047 13.8 2.0 1.7 8.8 0.0 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) TRCF PF03461.15 GAX11788.1 - 0.049 14.0 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 TRCF domain AAA_22 PF13401.6 GAX11788.1 - 0.15 12.4 0.0 0.45 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Stk19 PF10494.9 GAX11789.1 - 3.6e-06 26.9 0.0 6.6e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 MAPEG PF01124.18 GAX11790.1 - 1.4e-10 41.2 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 MAPEG family Lactamase_B_2 PF12706.7 GAX11793.1 - 0.0021 17.6 0.0 0.036 13.6 0.0 2.6 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Mito_carr PF00153.27 GAX11795.1 - 7.7e-50 166.8 5.4 2.1e-16 59.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C48 PF02902.19 GAX11796.1 - 3.5e-24 85.9 0.7 3.5e-24 85.9 0.7 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain LRR_8 PF13855.6 GAX11797.1 - 7.6e-22 76.8 17.0 1.5e-10 40.6 0.9 5.3 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAX11797.1 - 1.8e-20 72.6 15.0 5.8e-05 23.4 0.1 5.4 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX11797.1 - 3.5e-10 39.0 17.7 2.5 9.0 0.1 9.7 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_5 PF13306.6 GAX11797.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 GAX11797.1 - 2.6 8.3 15.2 8.6 6.7 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich repeat zf-GRF PF06839.12 GAX11798.1 - 3.9e-07 30.1 1.5 1.5e-06 28.1 1.5 2.2 1 0 0 1 1 1 1 GRF zinc finger zf-UBR PF02207.20 GAX11798.1 - 5.1e-06 26.5 15.4 5.1e-06 26.5 15.4 4.6 4 1 1 5 5 5 1 Putative zinc finger in N-recognin (UBR box) Sgf11 PF08209.11 GAX11798.1 - 0.25 10.9 5.9 0.28 10.8 0.6 3.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) E3_UbLigase_R4 PF13764.6 GAX11800.1 - 1e-84 285.3 0.0 2e-43 148.7 0.0 3.8 2 2 0 2 2 2 2 E3 ubiquitin-protein ligase UBR4 DUF3337 PF11816.8 GAX11800.1 - 0.046 13.6 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Radical_SAM PF04055.21 GAX11801.1 - 6.3e-22 78.7 0.0 1.4e-21 77.5 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 GAX11801.1 - 2.9e-18 66.0 0.0 6.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 GAX11801.1 - 2.6e-10 40.7 0.0 2.7e-08 34.1 0.0 2.5 1 1 0 1 1 1 1 Flavodoxin SR-25 PF10500.9 GAX11801.1 - 0.18 11.4 14.8 0.2 11.2 12.9 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 GAX11801.1 - 3.4 8.0 15.4 1.7 9.0 12.2 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain GET2 PF08690.10 GAX11802.1 - 0.00027 20.7 3.5 0.00038 20.2 3.5 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 Dicty_REP PF05086.12 GAX11802.1 - 0.0029 15.7 8.9 0.0038 15.3 8.9 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein PNMA PF14893.6 GAX11802.1 - 0.051 13.0 3.4 0.073 12.5 3.4 1.2 1 0 0 1 1 1 0 PNMA DUF2673 PF10880.8 GAX11802.1 - 0.13 12.4 0.5 0.27 11.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) ABC2_membrane PF01061.24 GAX11803.1 - 1.4e-29 103.1 18.6 1.4e-29 103.1 18.6 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAX11803.1 - 2.4e-26 92.9 0.1 3.9e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX11803.1 - 6.6e-08 32.0 13.2 1.1e-07 31.3 13.2 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAX11803.1 - 0.00022 21.1 0.1 0.00072 19.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 GAX11803.1 - 0.00027 20.9 2.5 0.011 15.5 0.2 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX11803.1 - 0.0016 18.9 0.1 0.0031 17.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAX11803.1 - 0.0021 17.5 0.3 0.065 12.7 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 GAX11803.1 - 0.041 13.8 0.1 0.19 11.7 0.0 1.8 1 1 0 2 2 2 0 Rad17 P-loop domain AAA_35 PF14516.6 GAX11803.1 - 0.048 12.5 0.4 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 GAX11803.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAX11803.1 - 0.11 12.8 0.2 0.26 11.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX11803.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX11803.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAX11803.1 - 0.21 11.3 1.4 1.8 8.3 0.4 2.4 1 1 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 GAX11804.1 - 5.4e-58 195.4 0.0 1.1e-30 107.0 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 GAX11804.1 - 5.8e-50 170.3 26.1 2.4e-35 122.2 12.5 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 GAX11804.1 - 2.2e-15 57.3 0.0 0.00015 21.7 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 GAX11804.1 - 0.0001 22.0 2.4 0.23 11.1 0.2 2.8 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.6 GAX11804.1 - 0.00039 21.0 4.7 0.0033 18.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAX11804.1 - 0.0016 18.8 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX11804.1 - 0.016 15.5 0.3 2.2 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 GAX11804.1 - 0.018 14.5 0.3 1.1 8.6 0.0 3.3 2 2 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 GAX11804.1 - 0.021 14.5 2.4 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 GAX11804.1 - 0.028 14.3 3.4 1 9.1 0.5 2.4 2 0 0 2 2 2 0 MukB N-terminal RsgA_GTPase PF03193.16 GAX11804.1 - 0.028 14.3 0.4 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 GAX11804.1 - 0.07 12.9 4.1 0.49 10.2 0.8 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.6 GAX11804.1 - 0.11 12.1 0.3 2.3 7.8 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 GAX11804.1 - 0.12 11.6 1.3 2 7.6 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 GAX11804.1 - 0.13 12.4 0.1 11 6.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Glyco_hydro_3_C PF01915.22 GAX11805.1 - 8.4e-47 159.8 0.0 1.3e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAX11805.1 - 2.4e-42 145.4 0.0 3.6e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAX11805.1 - 2e-18 66.3 0.0 8.1e-18 64.3 0.0 2.2 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2523 PF10734.9 GAX11805.1 - 0.1 13.2 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) Y_phosphatase3 PF13350.6 GAX11806.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Methyltransf_17 PF12692.7 GAX11807.1 - 0.057 13.4 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_25 PF13649.6 GAX11807.1 - 0.15 12.8 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX11807.1 - 0.19 12.5 0.0 0.32 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HYR PF02494.16 GAX11810.1 - 0.042 14.2 0.2 0.042 14.2 0.2 2.3 3 0 0 3 3 3 0 HYR domain DUF1533 PF07550.11 GAX11810.1 - 0.16 11.9 1.0 0.37 10.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Kinesin PF00225.23 GAX11811.1 - 2.6e-22 79.2 0.1 3.4e-21 75.5 0.0 2.8 2 1 0 2 2 2 1 Kinesin motor domain LRR_8 PF13855.6 GAX11813.1 - 9.6e-36 121.4 56.0 2e-06 27.5 0.9 13.1 8 4 2 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 GAX11813.1 - 5.9e-33 112.4 59.0 0.00017 21.9 0.3 15.2 10 4 8 19 19 19 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX11813.1 - 7.7e-10 37.9 38.9 3.7 8.5 0.1 16.0 18 1 1 19 19 19 4 Leucine Rich Repeat LRRNT_2 PF08263.12 GAX11813.1 - 0.0076 16.5 30.9 0.067 13.5 1.7 4.8 5 0 0 5 5 5 3 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 GAX11813.1 - 0.011 15.8 43.7 3.3 8.0 0.1 13.5 16 0 0 16 16 16 0 Leucine Rich repeat ADH_zinc_N_2 PF13602.6 GAX11814.1 - 2.8e-14 54.3 0.0 1.8e-13 51.7 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAX11814.1 - 2.6e-11 43.6 0.0 6.1e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX11814.1 - 0.0038 17.1 0.1 0.082 12.8 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain FKBP_C PF00254.28 GAX11815.1 - 2.1e-17 63.2 0.0 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-C3HC4_3 PF13920.6 GAX11816.1 - 8.8e-10 38.3 6.4 8.8e-10 38.3 6.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX11816.1 - 4.2e-09 36.6 11.2 4.2e-09 36.6 11.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GAX11816.1 - 1.2e-08 34.6 9.4 1.2e-08 34.6 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX11816.1 - 4.1e-08 32.9 8.8 4.1e-08 32.9 8.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX11816.1 - 7.8e-08 32.5 7.7 7.8e-08 32.5 7.7 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAX11816.1 - 5.1e-07 29.5 6.9 5.1e-07 29.5 6.9 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAX11816.1 - 1.2e-06 28.5 3.1 1.2e-06 28.5 3.1 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX11816.1 - 8.9e-06 25.6 7.9 8.9e-06 25.6 7.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 GAX11816.1 - 0.0032 17.2 10.1 0.015 15.1 10.1 2.1 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAX11816.1 - 0.0046 17.1 6.6 0.0046 17.1 6.6 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 GAX11816.1 - 0.024 14.4 2.1 0.086 12.6 2.1 2.0 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 GAX11816.1 - 0.041 14.0 3.1 0.041 14.0 3.1 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 GAX11816.1 - 0.23 11.6 7.8 0.18 11.8 5.4 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 GAX11816.1 - 0.39 10.9 7.1 0.35 11.0 4.2 2.5 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-P11 PF03854.14 GAX11816.1 - 0.44 10.3 13.8 0.16 11.7 9.3 2.3 2 1 0 2 2 2 0 P-11 zinc finger DUF1272 PF06906.11 GAX11816.1 - 0.7 10.0 9.9 0.19 11.9 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 GAX11816.1 - 1.1 8.9 9.9 0.7 9.6 6.0 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 GAX11816.1 - 1.4 9.0 9.2 1.2 9.3 6.5 2.0 2 0 0 2 2 2 0 Double zinc ribbon DUF1084 PF06454.11 GAX11817.1 - 0.002 17.5 12.9 0.0037 16.7 12.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) MASE3 PF17159.4 GAX11817.1 - 0.03 14.0 17.7 0.066 12.8 0.1 3.1 3 1 0 3 3 3 0 Membrane-associated sensor domain Dickkopf_N PF04706.12 GAX11818.1 - 5.5 7.5 64.0 0.18 12.3 10.9 5.5 3 1 1 5 5 5 0 Dickkopf N-terminal cysteine-rich region ABC_tran PF00005.27 GAX11819.1 - 1.3e-56 190.9 0.0 4.4e-30 105.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 GAX11819.1 - 2.5e-52 178.1 31.5 1.5e-34 119.6 11.8 2.9 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 GAX11819.1 - 5.6e-15 55.9 0.0 3.9e-05 23.6 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX11819.1 - 0.00092 19.6 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 GAX11819.1 - 0.0024 17.3 1.9 1.1 8.7 0.0 3.7 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAX11819.1 - 0.0031 17.4 0.2 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAX11819.1 - 0.0032 17.6 0.7 0.33 11.1 0.1 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.6 GAX11819.1 - 0.012 16.1 0.0 0.012 16.1 0.0 3.0 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 GAX11819.1 - 0.083 12.6 1.1 0.81 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX11819.1 - 0.14 12.5 0.2 2.9 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAX11819.1 - 0.22 11.1 4.1 3.7 7.1 1.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 GAX11819.1 - 0.28 10.4 0.8 2.1 7.6 0.1 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_29 PF13555.6 GAX11819.1 - 0.38 10.5 5.4 0.83 9.4 0.4 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_15 PF13175.6 GAX11819.1 - 1.9 8.1 3.5 8 6.1 0.1 3.3 4 0 0 4 4 4 0 AAA ATPase domain Galactosyl_T PF01762.21 GAX11820.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase RTP801_C PF07809.11 GAX11821.1 - 0.0011 18.9 1.9 0.018 15.0 0.0 2.6 2 1 1 3 3 3 2 RTP801 C-terminal region DNA_pol_phi PF04931.13 GAX11822.1 - 2.2e-29 102.2 16.5 1.9e-28 99.1 1.1 5.5 4 2 0 4 4 4 3 DNA polymerase phi DUF3385 PF11865.8 GAX11822.1 - 0.9 9.4 5.5 9.3 6.1 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) RYDR_ITPR PF01365.21 GAX11823.1 - 0.68 9.3 3.9 0.43 10.0 0.7 2.3 1 1 0 2 2 2 0 RIH domain MORN PF02493.20 GAX11824.1 - 2.2e-14 52.4 37.1 5.6e-06 25.9 1.1 7.0 7 0 0 7 7 7 4 MORN repeat Dicty_REP PF05086.12 GAX11825.1 - 0.6 8.0 1.7 0.8 7.6 1.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MGDG_synth PF06925.11 GAX11826.1 - 1e-22 81.1 0.0 2e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 GAX11826.1 - 4.7e-16 59.2 0.0 8.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 GAX11826.1 - 6.9e-10 38.7 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX11826.1 - 3e-08 34.2 0.0 7.3e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 GAX11826.1 - 0.00015 20.8 0.0 0.00028 19.9 0.0 1.4 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase PRMT5 PF05185.16 GAX11826.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PNP_UDP_1 PF01048.20 GAX11827.1 - 1.2e-44 152.4 0.2 1.4e-44 152.1 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Peptidase_M16_M PF16187.5 GAX11828.1 - 1.3e-62 211.7 0.1 2.4e-62 210.8 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX11828.1 - 2.1e-32 112.2 0.0 3.6e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX11828.1 - 3.9e-28 98.7 0.0 2.5e-19 70.0 0.0 3.6 3 1 0 3 3 3 2 Peptidase M16 inactive domain DUF2070 PF09843.9 GAX11829.1 - 2.1 6.5 13.1 0.43 8.8 4.7 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) LSM PF01423.22 GAX11830.1 - 1.3e-15 56.9 0.3 1.6e-15 56.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAX11830.1 - 0.0082 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Hfq protein EMC3_TMCO1 PF01956.16 GAX11831.1 - 7.6e-10 38.8 0.2 1.6e-09 37.8 0.1 1.5 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RRM_3 PF08777.11 GAX11831.1 - 0.75 9.9 3.5 1.2 9.2 3.5 1.3 1 0 0 1 1 1 0 RNA binding motif Use1 PF09753.9 GAX11832.1 - 0.00024 20.9 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Rootletin PF15035.6 GAX11832.1 - 0.019 15.0 2.7 0.048 13.7 2.7 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2207 PF09972.9 GAX11832.1 - 0.028 13.2 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syntaxin-6_N PF09177.11 GAX11832.1 - 0.054 14.0 0.6 0.14 12.7 0.1 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PDGLE PF13190.6 GAX11832.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 PDGLE domain T2SSF PF00482.23 GAX11832.1 - 0.13 12.2 2.4 0.33 10.9 2.1 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Wbp11 PF09429.10 GAX11832.1 - 0.25 11.8 2.8 0.14 12.5 0.7 1.7 2 0 0 2 2 2 0 WW domain binding protein 11 ASD2 PF08687.11 GAX11832.1 - 0.34 10.4 4.1 3.8 7.0 3.9 2.1 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 DivIC PF04977.15 GAX11832.1 - 0.43 10.4 2.4 4.5 7.1 0.0 3.0 2 1 1 3 3 3 0 Septum formation initiator SNARE PF05739.19 GAX11832.1 - 1.1 9.3 5.5 0.26 11.3 0.4 2.7 3 1 0 3 3 3 0 SNARE domain TPR_2 PF07719.17 GAX11833.1 - 7.5e-12 44.4 1.4 0.0098 15.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX11833.1 - 9.2e-05 22.1 1.0 3.9 7.4 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX11833.1 - 0.00072 20.1 1.0 0.15 12.7 0.3 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX11833.1 - 0.048 13.9 3.0 4.5 7.6 0.3 3.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX11833.1 - 0.057 13.1 0.4 0.22 11.3 0.0 2.1 2 1 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 GAX11833.1 - 0.088 13.7 0.9 27 5.9 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX11833.1 - 0.11 13.2 6.6 2.1 9.2 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat FMN_red PF03358.15 GAX11834.1 - 6.8e-23 81.1 0.0 8.7e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAX11834.1 - 9.8e-06 25.4 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Smr PF01713.21 GAX11834.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Smr domain Glyco_hydro_20 PF00728.22 GAX11835.1 - 7.3e-103 344.7 0.9 2.1e-102 343.1 0.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAX11835.1 - 6.6e-09 36.5 0.0 1.4e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAX11835.1 - 3.1e-08 34.4 0.0 8e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Dus PF01207.17 GAX11836.1 - 6.8e-55 186.3 0.2 3.5e-53 180.7 0.2 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GAX11836.1 - 0.00053 19.5 0.0 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 GAX11836.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.17 GAX11836.1 - 0.016 14.6 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase G3P_antiterm PF04309.12 GAX11836.1 - 0.041 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.25 GAX11836.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Stn1 PF10451.9 GAX11837.1 - 0.13 11.2 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 SDA1 PF05285.12 GAX11838.1 - 2.2e-45 155.6 35.3 2.2e-45 155.6 35.3 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 GAX11838.1 - 2.6e-05 24.4 0.1 6.4e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 NUC130/3NT domain PI3_PI4_kinase PF00454.27 GAX11839.1 - 4.7e-27 95.4 0.2 1.1e-24 87.6 0.2 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-MYND PF01753.18 GAX11840.1 - 1.7e-09 37.6 18.2 1.7e-09 37.6 18.2 2.6 2 1 0 2 2 2 1 MYND finger zf-RING_2 PF13639.6 GAX11840.1 - 0.00031 21.0 6.6 0.00031 21.0 6.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GAX11840.1 - 0.0014 18.5 6.8 0.0014 18.5 6.8 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX11840.1 - 0.0038 17.1 7.1 0.0038 17.1 7.1 2.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX11840.1 - 0.0041 17.1 2.4 0.0041 17.1 2.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAX11840.1 - 0.0089 15.9 3.9 0.0089 15.9 3.9 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C6H2 PF15801.5 GAX11840.1 - 0.01 16.1 19.2 0.012 15.9 13.9 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-C3HC4_2 PF13923.6 GAX11840.1 - 0.025 14.4 7.5 0.025 14.4 7.5 2.9 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AhpC-TSA PF00578.21 GAX11840.1 - 0.42 10.5 1.6 1.6 8.6 0.0 2.5 3 1 0 3 3 3 0 AhpC/TSA family zinc_ribbon_9 PF14369.6 GAX11840.1 - 7.2 7.0 12.9 0.16 12.2 5.8 2.1 2 0 0 2 2 2 0 zinc-ribbon TPR_12 PF13424.6 GAX11841.1 - 1.6e-18 66.7 26.6 1.5e-06 28.3 4.8 7.2 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX11841.1 - 3.3e-11 42.4 9.4 0.00077 19.4 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX11841.1 - 1.5e-09 37.4 20.6 0.00089 19.1 2.8 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 GAX11841.1 - 6.8e-09 35.3 0.0 1.9e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain SPO22 PF08631.10 GAX11841.1 - 1.2e-06 28.2 2.3 1.2e-06 28.2 2.3 3.1 3 1 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_1 PF00515.28 GAX11841.1 - 5e-06 26.1 3.1 0.27 11.1 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX11841.1 - 0.00025 21.0 3.3 0.84 10.0 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX11841.1 - 0.0003 20.6 7.4 0.14 12.3 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Ras PF00071.22 GAX11841.1 - 0.0069 16.0 0.0 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 Ras family RHH_8 PF17723.1 GAX11841.1 - 0.084 13.1 0.1 0.42 10.8 0.1 2.2 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family DUF627 PF04781.12 GAX11841.1 - 0.13 12.3 4.5 8.9 6.4 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF627) Roc PF08477.13 GAX11841.1 - 0.15 12.3 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 GAX11841.1 - 0.15 12.4 1.3 0.94 9.8 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain TPR_14 PF13428.6 GAX11841.1 - 0.77 10.7 24.0 5.4 8.1 0.0 7.0 8 1 0 8 8 6 0 Tetratricopeptide repeat GST_N PF02798.20 GAX11842.1 - 5.4e-08 33.1 0.0 1.8e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAX11842.1 - 1.7e-05 25.1 0.0 3.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAX11842.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAX11842.1 - 0.00017 22.3 0.0 0.00054 20.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 GAX11842.1 - 0.00021 21.5 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAX11842.1 - 0.00023 21.5 0.0 0.00092 19.5 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_2 PF13409.6 GAX11842.1 - 0.0024 18.1 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX11842.1 - 0.012 15.6 0.2 0.056 13.5 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain HECT PF00632.25 GAX11843.1 - 8.1e-14 51.8 0.1 5.7e-11 42.5 0.0 2.3 1 1 0 2 2 2 2 HECT-domain (ubiquitin-transferase) K_oxygenase PF13434.6 GAX11844.1 - 1.3e-13 50.8 0.0 8.6e-10 38.3 0.0 3.0 2 2 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAX11844.1 - 6.5e-10 38.7 0.0 1.2e-06 28.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX11844.1 - 2.8e-05 24.1 2.4 0.035 14.1 0.5 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAX11844.1 - 6.8e-05 22.3 0.0 0.19 10.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX11844.1 - 0.0055 17.2 0.0 0.019 15.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX11844.1 - 0.043 14.1 0.5 7.1 7.0 0.0 3.0 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX11844.1 - 0.11 11.5 0.0 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 GAX11844.1 - 0.33 10.2 1.7 5.5 6.2 0.5 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 GAX11844.1 - 0.86 9.1 2.9 27 4.2 0.1 3.5 2 2 0 3 3 3 0 FAD dependent oxidoreductase Glyco_tranf_2_4 PF13704.6 GAX11845.1 - 5e-05 23.7 3.0 0.00016 22.1 3.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 EamA PF00892.20 GAX11846.1 - 2.1e-27 95.9 17.7 3.3e-15 56.5 2.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX11846.1 - 0.00073 18.9 4.0 0.015 14.5 0.2 2.2 1 1 1 2 2 2 2 Purine nucleobase transmembrane transport SLC35F PF06027.12 GAX11846.1 - 0.0032 17.0 4.1 0.06 12.8 3.7 2.7 1 1 2 3 3 3 1 Solute carrier family 35 TPT PF03151.16 GAX11846.1 - 0.039 13.3 4.9 0.75 9.1 0.4 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.20 GAX11848.1 - 4.5e-27 94.9 19.3 2.6e-15 56.8 5.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 GAX11848.1 - 0.0027 17.3 2.1 0.0089 15.6 1.0 2.1 1 1 1 2 2 2 1 Solute carrier family 35 EamA PF00892.20 GAX11849.1 - 3.4e-24 85.6 22.3 3.6e-12 46.6 8.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF3392 PF11872.8 GAX11849.1 - 0.1 12.9 1.1 0.35 11.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) SLC35F PF06027.12 GAX11849.1 - 0.58 9.6 7.5 1.1 8.7 4.7 2.2 1 1 1 2 2 2 0 Solute carrier family 35 Ion_trans PF00520.31 GAX11850.1 - 2.7e-12 46.5 14.1 2.7e-12 46.5 14.1 2.4 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 GAX11850.1 - 6e-06 25.2 6.1 6e-06 25.2 6.1 2.6 3 0 0 3 3 3 1 Polycystin cation channel DUF3339 PF11820.8 GAX11850.1 - 0.061 13.5 0.2 0.061 13.5 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3339) Herpes_capsid PF06112.11 GAX11850.1 - 0.62 10.1 0.0 0.62 10.1 0.0 2.7 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein CCT PF06203.14 GAX11852.1 - 9.8e-16 57.5 14.6 9.8e-16 57.5 14.6 1.8 2 0 0 2 2 2 1 CCT motif Fmp27_WPPW PF10359.9 GAX11854.1 - 0.014 14.3 1.5 0.021 13.7 1.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ADIP PF11559.8 GAX11854.1 - 0.018 15.1 4.1 0.035 14.2 4.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 GAX11854.1 - 0.02 15.0 0.3 0.02 15.0 0.3 2.0 2 1 0 2 2 2 0 bZIP transcription factor DUF4988 PF16378.5 GAX11854.1 - 0.039 13.6 0.3 0.064 12.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function ZapB PF06005.12 GAX11854.1 - 0.039 14.4 5.2 0.089 13.2 5.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB NEMO PF11577.8 GAX11854.1 - 0.055 13.5 5.1 0.12 12.4 4.6 1.9 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO DUF3552 PF12072.8 GAX11854.1 - 0.068 12.6 4.6 0.12 11.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SKA2 PF16740.5 GAX11854.1 - 0.076 12.8 4.4 0.052 13.3 1.3 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TFR_dimer PF04253.15 GAX11854.1 - 0.098 12.8 0.6 0.67 10.1 0.2 2.1 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Rho_Binding PF08912.11 GAX11854.1 - 0.13 13.1 4.5 0.42 11.5 4.5 1.9 1 0 0 1 1 1 0 Rho Binding Nif11 PF07862.11 GAX11854.1 - 0.16 12.3 0.4 7.5 6.9 0.1 2.8 2 0 0 2 2 2 0 Nif11 domain Ax_dynein_light PF10211.9 GAX11854.1 - 0.17 11.9 5.0 0.34 10.8 5.0 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Csm1_N PF18504.1 GAX11854.1 - 0.19 12.1 5.2 0.43 10.9 5.2 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain TSC22 PF01166.18 GAX11854.1 - 0.34 11.2 1.9 0.87 9.9 1.9 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family CALM_bind PF16025.5 GAX11854.1 - 0.72 10.4 5.8 2.1 8.9 3.0 2.4 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding PRKG1_interact PF15898.5 GAX11854.1 - 4.2 8.3 10.0 0.98 10.4 5.6 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.15 GAX11854.1 - 6.7 6.9 9.5 2.1 8.5 4.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Ank_2 PF12796.7 GAX11856.1 - 1.4e-16 60.8 0.0 5.6e-08 33.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX11856.1 - 6.9e-16 56.7 0.2 0.00049 20.3 0.0 4.8 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 GAX11856.1 - 2.3e-10 40.8 0.0 1.4e-07 31.9 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 GAX11856.1 - 5.6e-10 39.2 16.1 1.1e-09 38.2 16.1 1.5 1 0 0 1 1 1 1 MYND finger Ank PF00023.30 GAX11856.1 - 8.4e-10 38.7 0.0 0.096 13.2 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GAX11856.1 - 2.2e-06 27.8 0.4 0.0021 18.4 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) zf-HIT PF04438.16 GAX11856.1 - 1.4e-05 24.8 4.3 2.4e-05 24.1 4.3 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.6 GAX11856.1 - 0.19 11.9 6.9 0.31 11.2 6.9 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ank_2 PF12796.7 GAX11857.1 - 6.8e-17 61.8 0.0 8.5e-14 51.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX11857.1 - 2.5e-15 55.0 0.0 0.00033 20.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 GAX11857.1 - 1.9e-12 47.4 0.0 2.8e-06 27.8 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX11857.1 - 2.4e-11 43.6 0.1 1.6e-05 25.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat zf-MYND PF01753.18 GAX11857.1 - 3.3e-11 43.1 16.8 5.8e-11 42.3 16.8 1.4 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.6 GAX11857.1 - 7.7e-08 32.5 0.2 1e-06 28.9 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) zf-HIT PF04438.16 GAX11857.1 - 3.4e-05 23.6 2.8 6.3e-05 22.8 2.8 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.6 GAX11857.1 - 1.5 9.0 8.9 3 8.0 8.9 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_L7Ae PF01248.26 GAX11858.1 - 2.2e-22 78.6 1.0 2.9e-22 78.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 GAX11858.1 - 0.0041 17.2 0.6 0.018 15.1 0.4 1.9 1 1 1 2 2 2 1 RNase P subunit Pop3 GTP_EFTU PF00009.27 GAX11859.1 - 3.5e-57 193.1 0.2 4.6e-57 192.7 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAX11859.1 - 1.1e-28 99.8 0.0 2e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAX11859.1 - 2e-16 60.1 2.3 4.7e-16 58.9 2.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX11859.1 - 0.00013 22.0 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 GAX11859.1 - 0.0022 17.6 0.1 0.0075 15.9 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAX11859.1 - 0.011 15.5 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 GAX11859.1 - 0.019 14.9 0.1 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 GAX11859.1 - 0.11 12.2 0.1 21 4.8 0.0 2.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_S8 PF00410.19 GAX11859.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 Vps39_1 PF10366.9 GAX11859.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Sod_Cu PF00080.20 GAX11860.1 - 3e-36 124.7 1.8 3.6e-36 124.4 1.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) zf-MYND PF01753.18 GAX11861.1 - 4.4e-12 45.9 15.2 4.4e-12 45.9 15.2 2.0 1 1 1 2 2 2 1 MYND finger zf-Mss51 PF13824.6 GAX11861.1 - 0.0051 16.9 7.0 0.0085 16.2 7.0 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 GAX11861.1 - 0.0062 16.4 5.1 0.01 15.7 5.1 1.3 1 0 0 1 1 1 1 HIT zinc finger TerB PF05099.13 GAX11861.1 - 0.042 13.8 0.3 0.061 13.3 0.3 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB CHASE PF03924.13 GAX11863.1 - 0.0046 16.9 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 CHASE domain Tmemb_9 PF05434.11 GAX11863.1 - 0.052 13.4 0.7 0.11 12.4 0.3 1.7 2 0 0 2 2 2 0 TMEM9 PDEase_I PF00233.19 GAX11864.1 - 1.7e-33 116.4 0.1 2.6e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 GAX11864.1 - 1.5e-20 73.6 0.0 3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3083 PF11281.8 GAX11864.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) DnaJ PF00226.31 GAX11865.1 - 3.2e-20 72.0 0.1 1.7e-19 69.7 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.7 GAX11865.1 - 9.8e-08 32.1 5.3 1.3e-07 31.8 3.6 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAX11865.1 - 4e-07 30.2 4.9 1.2e-06 28.6 4.9 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAX11865.1 - 4.1e-05 23.8 2.0 0.00012 22.4 1.3 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAX11865.1 - 0.013 16.3 1.3 0.039 14.8 1.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 GAX11865.1 - 0.015 15.4 4.1 0.041 14.0 4.1 1.7 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2 PF00096.26 GAX11865.1 - 0.31 11.6 2.7 0.85 10.2 2.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Bestrophin PF01062.21 GAX11865.1 - 0.52 9.6 2.5 1.1 8.6 2.5 1.6 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Bac_luciferase PF00296.20 GAX11865.1 - 0.73 9.2 9.7 1.4 8.3 9.7 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase Ank_2 PF12796.7 GAX11866.1 - 3.6e-18 65.9 0.1 1.4e-07 32.0 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX11866.1 - 3.8e-14 52.9 0.1 0.0002 21.9 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX11866.1 - 3e-12 45.6 0.1 0.52 11.0 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAX11866.1 - 6.3e-09 35.9 0.6 0.0011 19.2 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX11866.1 - 2.4e-08 34.1 0.9 3.3 8.3 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Glyco_transf_7C PF02709.14 GAX11867.1 - 6.2e-22 77.1 0.2 1.4e-21 75.9 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 GAX11867.1 - 2e-19 69.6 0.0 3.1e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 WW PF00397.26 GAX11867.1 - 1.2e-08 34.8 1.7 2.6e-08 33.8 1.7 1.6 1 0 0 1 1 1 1 WW domain NYN PF01936.18 GAX11867.1 - 0.034 14.6 0.1 0.074 13.5 0.1 1.6 1 1 0 1 1 1 0 NYN domain CHGN PF05679.16 GAX11867.1 - 0.09 11.6 0.0 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Chondroitin N-acetylgalactosaminyltransferase Na_H_Exchanger PF00999.21 GAX11868.1 - 2.9e-47 161.3 36.4 3.9e-47 160.8 36.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EF-hand_7 PF13499.6 GAX11868.1 - 4e-15 56.0 0.9 4e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX11868.1 - 7.3e-15 53.3 1.9 1.4e-05 24.3 0.0 3.6 3 0 0 3 3 3 2 EF hand TrkA_N PF02254.18 GAX11868.1 - 1.2e-14 54.6 0.0 4.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain EF-hand_6 PF13405.6 GAX11868.1 - 1.2e-13 49.8 0.3 5.8e-05 22.7 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GAX11868.1 - 5.3e-13 47.8 2.5 1.2e-06 27.7 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAX11868.1 - 1.1e-08 34.7 1.3 0.045 13.6 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAX11868.1 - 0.022 15.1 0.0 0.08 13.3 0.0 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Histone_H2A_C PF16211.5 GAX11869.1 - 2.8e-20 71.8 1.4 6.2e-20 70.6 1.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAX11869.1 - 2.1e-14 54.0 0.0 2.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX11869.1 - 0.0035 17.6 0.0 0.0045 17.2 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TF_Zn_Ribbon PF08271.12 GAX11870.1 - 0.032 13.8 2.3 0.068 12.7 2.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Otopetrin PF03189.13 GAX11870.1 - 0.2 10.4 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Otopetrin DUF3306 PF11748.8 GAX11870.1 - 0.2 12.5 8.2 0.49 11.3 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FAM176 PF14851.6 GAX11870.1 - 0.34 10.6 5.1 0.34 10.6 0.3 2.4 2 0 0 2 2 2 0 FAM176 family zf-RRN7 PF11781.8 GAX11870.1 - 1.8 8.3 4.1 3.7 7.3 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CENP-B_dimeris PF09026.10 GAX11870.1 - 2 8.9 14.4 8.5 6.8 4.7 3.9 5 0 0 5 5 5 0 Centromere protein B dimerisation domain Fer4_13 PF13370.6 GAX11871.1 - 0.025 15.1 0.2 0.055 14.0 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I DUF4316 PF14195.6 GAX11871.1 - 0.1 12.4 0.3 0.49 10.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4316) Aldedh PF00171.22 GAX11872.1 - 1.5e-117 393.0 0.3 1.7e-117 392.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltrans_RNA PF04452.14 GAX11872.1 - 0.08 12.3 0.2 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 RNA methyltransferase Matrilin_ccoil PF10393.9 GAX11873.1 - 0.2 11.6 3.4 8.8 6.3 0.0 2.7 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin UBA PF00627.31 GAX11873.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain Aldedh PF00171.22 GAX11874.1 - 5.3e-123 410.9 0.0 6.6e-123 410.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HMG_box PF00505.19 GAX11875.1 - 8.4e-32 109.4 10.7 1e-15 57.9 0.7 3.1 2 1 1 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX11875.1 - 1.4e-19 70.4 10.0 1.7e-09 38.2 0.5 2.9 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.12 GAX11875.1 - 0.00012 21.9 0.2 0.26 11.3 0.0 2.8 3 0 0 3 3 3 2 CHDNT (NUC034) domain SRTM1 PF15872.5 GAX11875.1 - 0.077 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 UPF0239 PF06783.11 GAX11875.1 - 3.1 8.1 0.0 3.1 8.1 0.0 4.1 5 1 0 5 5 5 0 Uncharacterised protein family (UPF0239) DUF4330 PF14221.6 GAX11875.1 - 3.1 8.0 6.4 2.7 8.2 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4330) UPF0014 PF03649.13 GAX11877.1 - 1.3e-69 234.3 18.6 1.8e-69 233.8 18.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) ABC_tran PF00005.27 GAX11877.1 - 1e-22 81.1 0.0 2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAX11877.1 - 0.0061 17.0 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAX11877.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX11877.1 - 0.035 14.4 0.1 0.11 12.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 GAX11877.1 - 0.045 12.5 0.1 0.48 9.2 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 GAX11877.1 - 0.063 13.0 0.0 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAX11877.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 GAX11877.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX11877.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase LRR_8 PF13855.6 GAX11879.1 - 4.6e-15 55.1 12.3 0.00039 20.1 0.9 6.2 4 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 GAX11879.1 - 5.5e-10 39.3 16.1 0.074 13.5 0.0 6.2 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX11879.1 - 9.8e-05 22.4 11.9 20 6.3 1.5 9.2 10 1 1 11 11 11 2 Leucine Rich Repeat Claudin_3 PF06653.11 GAX11879.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like LRR_8 PF13855.6 GAX11880.1 - 1.3e-28 98.5 24.5 3.7e-06 26.6 1.8 7.3 4 2 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 GAX11880.1 - 4.7e-15 55.5 35.0 0.0094 16.4 0.5 8.8 1 1 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX11880.1 - 1.1e-10 40.5 16.5 7.1 7.6 0.1 10.7 11 1 1 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.6 GAX11880.1 - 1.6e-08 33.9 15.9 0.26 11.5 0.0 8.0 7 0 0 7 7 7 5 Leucine Rich repeat B12D PF06522.11 GAX11881.1 - 0.023 14.5 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PRIMA1 PF16101.5 GAX11882.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 B12D PF06522.11 GAX11882.1 - 0.19 11.6 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Metallophos PF00149.28 GAX11883.1 - 8.3e-05 23.2 1.8 0.00071 20.1 0.6 2.9 2 1 0 3 3 3 1 Calcineurin-like phosphoesterase Ntox15 PF15604.6 GAX11883.1 - 0.031 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Novel toxin 15 Solute_trans_a PF03619.16 GAX11884.1 - 2.2e-82 276.6 9.6 2.9e-82 276.2 9.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Apolipoprotein PF01442.18 GAX11884.1 - 0.016 15.1 2.6 0.031 14.1 2.6 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4293 PF14126.6 GAX11884.1 - 0.07 13.4 11.3 0.19 12.0 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Fzo_mitofusin PF04799.13 GAX11884.1 - 0.1 12.1 3.2 0.11 12.0 1.3 2.0 2 0 0 2 2 2 0 fzo-like conserved region DUF1640 PF07798.11 GAX11884.1 - 0.79 9.7 7.2 1.4 9.0 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Lectin_N PF03954.14 GAX11884.1 - 1.1 9.0 4.6 0.89 9.3 2.2 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 GAX11884.1 - 2 8.5 6.9 1.5 8.9 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DDHD PF02862.17 GAX11885.1 - 7.6e-44 150.5 0.2 5.5e-43 147.7 0.2 2.3 1 1 0 1 1 1 1 DDHD domain GST_N_2 PF13409.6 GAX11886.1 - 3.3e-20 72.2 0.0 1.1e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX11886.1 - 4.8e-07 29.7 0.0 1.6e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX11886.1 - 8.1e-06 26.0 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX11886.1 - 0.0003 20.9 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX11886.1 - 0.0021 18.4 0.0 2.6 8.5 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain PhyH PF05721.13 GAX11890.1 - 2e-28 100.1 0.0 2.5e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Translin PF01997.16 GAX11891.1 - 7.6e-39 133.8 0.3 1.7e-23 83.7 0.0 2.3 2 0 0 2 2 2 2 Translin family DUF3731 PF12531.8 GAX11891.1 - 0.002 18.0 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 2 DNA-K related protein P-mevalo_kinase PF04275.14 GAX11892.1 - 0.043 13.8 0.3 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Phosphomevalonate kinase zf-CCCH_2 PF14608.6 GAX11892.1 - 0.18 12.3 18.3 0.078 13.5 4.8 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Lustrin_cystein PF14625.6 GAX11892.1 - 0.36 11.2 4.5 16 6.0 0.6 3.1 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain IL2 PF00715.17 GAX11892.1 - 1.3 9.0 5.1 0.53 10.2 1.1 2.3 2 0 0 2 2 2 0 Interleukin 2 Myf5 PF12232.8 GAX11892.1 - 2.4 9.0 6.9 0.27 12.0 0.4 2.9 3 0 0 3 3 3 0 Myogenic determination factor 5 UQ_con PF00179.26 GAX11895.1 - 1e-13 51.1 0.0 1.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ge1_WD40 PF16529.5 GAX11896.1 - 3.3e-07 29.6 0.0 6.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Prominin PF05478.11 GAX11896.1 - 0.017 13.2 1.1 0.028 12.4 1.1 1.2 1 0 0 1 1 1 0 Prominin Trimer_CC PF08954.11 GAX11896.1 - 0.069 12.7 1.5 0.17 11.5 1.5 1.6 1 0 0 1 1 1 0 Trimerisation motif Ribosomal_L16 PF00252.18 GAX11897.1 - 2e-36 124.9 0.2 2.5e-36 124.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Prefoldin_2 PF01920.20 GAX11898.1 - 0.7 9.9 11.6 1.2 9.1 3.3 3.3 3 1 1 4 4 4 0 Prefoldin subunit OmpH PF03938.14 GAX11898.1 - 1.7 8.9 8.5 1 9.7 2.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) T2SSM PF04612.12 GAX11898.1 - 2.3 8.3 6.5 0.85 9.7 1.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF547 PF04784.14 GAX11900.1 - 1.7e-20 73.3 0.0 3.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Glutaredoxin PF00462.24 GAX11900.1 - 2.7e-09 37.1 0.0 6.4e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin DEP PF00610.21 GAX11900.1 - 1.9e-08 34.2 0.0 4.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-RING_2 PF13639.6 GAX11901.1 - 9.2e-06 25.9 8.7 3.2e-05 24.2 8.7 2.0 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 GAX11901.1 - 8.8e-05 22.6 5.7 0.00034 20.7 5.7 2.0 1 0 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.22 GAX11901.1 - 0.0018 18.1 3.1 0.0018 18.1 3.1 2.0 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ANAPC11 PF12861.7 GAX11901.1 - 0.0022 18.0 3.4 0.007 16.4 3.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3950 PF13132.6 GAX11901.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) RINGv PF12906.7 GAX11901.1 - 0.099 12.8 7.8 0.34 11.1 7.8 2.0 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 GAX11901.1 - 0.15 12.0 7.6 0.41 10.6 7.6 1.8 1 0 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.25 GAX11901.1 - 0.17 11.8 8.3 0.41 10.6 8.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX11901.1 - 0.27 11.6 6.2 0.83 10.0 6.2 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zf_RING PF16744.5 GAX11901.1 - 0.82 9.8 3.4 2.2 8.4 3.4 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 GAX11901.1 - 1 9.1 7.8 4.3 7.0 7.8 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 GAX11901.1 - 7.1 6.6 8.9 21 5.1 8.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Guanylate_cyc PF00211.20 GAX11903.1 - 4.9e-08 32.8 0.3 2.3e-07 30.6 0.3 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Spt46 PF17734.1 GAX11903.1 - 0.14 11.9 3.0 2.8 7.7 1.1 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 LVIVD PF08309.11 GAX11904.1 - 8.3e-07 28.2 12.5 0.11 11.8 0.5 5.6 5 0 0 5 5 5 4 LVIVD repeat DnaJ PF00226.31 GAX11905.1 - 1.1e-17 63.8 1.2 2.3e-17 62.9 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain SKN1 PF03935.15 GAX11906.1 - 6.5e-62 209.6 10.1 3.8e-50 170.8 1.2 3.4 3 1 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAX11906.1 - 0.003 17.1 1.3 0.0039 16.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 EGF_2 PF07974.13 GAX11906.1 - 0.012 15.9 4.4 0.012 15.9 4.4 3.1 3 0 0 3 3 3 0 EGF-like domain Mad3_BUB1_I PF08311.12 GAX11908.1 - 8.8e-05 22.5 0.9 0.021 14.8 1.3 2.4 1 1 1 2 2 2 2 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 GAX11908.1 - 0.00012 22.6 3.9 0.17 12.8 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX11908.1 - 0.16 12.3 1.6 3.3 8.1 1.8 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4033 PF13225.6 GAX11909.1 - 1.6e-26 92.1 0.2 3.5e-26 91.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) adh_short PF00106.25 GAX11910.1 - 6.6e-25 87.7 0.1 6.9e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX11910.1 - 6.7e-15 55.3 0.1 4.9e-11 42.6 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX11910.1 - 2e-11 44.1 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX11910.1 - 6.4e-06 25.8 0.1 3.4e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAX11910.1 - 1.8e-05 24.1 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAX11910.1 - 0.0039 16.6 0.0 0.01 15.3 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAX11910.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAX11910.1 - 0.068 12.3 0.0 0.1 11.7 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Bestrophin PF01062.21 GAX11911.1 - 7.7e-31 107.6 0.1 1.7e-30 106.5 0.1 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel VRR_NUC PF08774.11 GAX11912.1 - 3.5e-13 49.5 0.1 1.1e-05 25.4 0.1 2.4 2 0 0 2 2 2 2 VRR-NUC domain RVT_2 PF07727.14 GAX11913.1 - 8.5e-35 120.5 0.1 1.5e-34 119.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TF_Zn_Ribbon PF08271.12 GAX11914.1 - 5.5e-09 35.4 0.3 1.1e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Prim_Zn_Ribbon PF08273.12 GAX11914.1 - 0.00063 20.0 0.3 0.0015 18.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase Lar_restr_allev PF14354.6 GAX11914.1 - 0.011 16.1 0.2 0.13 12.7 0.4 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 GAX11914.1 - 0.03 13.7 4.8 2.3 7.7 0.4 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 GAX11914.1 - 0.075 12.8 2.9 1.8 8.4 0.4 2.8 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 GAX11914.1 - 0.09 12.7 0.8 0.22 11.4 0.8 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Elf1 PF05129.13 GAX11914.1 - 0.12 12.5 0.3 0.29 11.2 0.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like IBR PF01485.21 GAX11914.1 - 0.13 12.5 0.5 0.32 11.2 0.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ammonium_transp PF00909.21 GAX11915.1 - 2.5e-99 332.7 27.0 3.2e-99 332.4 27.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM220 PF15071.6 GAX11915.1 - 8.9 7.1 9.2 0.21 12.4 0.4 2.7 3 0 0 3 3 3 0 Transmembrane family 220, helix Ammonium_transp PF00909.21 GAX11916.1 - 5.2e-102 341.5 24.9 6.5e-102 341.2 24.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM220 PF15071.6 GAX11916.1 - 0.22 12.3 3.0 0.31 11.8 0.3 2.6 2 0 0 2 2 2 0 Transmembrane family 220, helix CBM_6 PF03422.15 GAX11917.1 - 6.3e-37 126.7 6.0 2.8e-15 56.7 1.3 3.1 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX11917.1 - 1.4e-20 73.5 1.0 2.3e-06 27.7 0.2 3.4 3 0 0 3 3 3 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX11917.1 - 3e-05 24.3 5.3 0.074 13.3 0.7 3.5 3 1 0 3 3 3 2 Carbohydrate binding module (family 35) Barwin PF00967.17 GAX11917.1 - 0.13 12.1 0.1 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Barwin family Ank_2 PF12796.7 GAX11918.1 - 1.6e-27 95.9 0.1 2.3e-12 47.3 0.0 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX11918.1 - 2e-21 76.1 1.3 1.2e-12 48.1 0.1 4.1 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX11918.1 - 1.2e-20 73.3 1.0 8.7e-08 32.3 0.0 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX11918.1 - 1.2e-19 68.3 0.1 1.3e-07 31.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAX11918.1 - 6.2e-16 58.1 0.0 1.6e-07 31.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Bestrophin PF01062.21 GAX11919.1 - 1.3e-27 97.0 0.2 1.9e-27 96.4 0.2 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PPC PF04151.15 GAX11920.1 - 5.9e-05 24.1 0.7 0.00014 22.9 0.1 1.8 2 0 0 2 2 2 1 Bacterial pre-peptidase C-terminal domain PC4 PF02229.16 GAX11922.1 - 0.052 13.2 0.1 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) Pepdidase_M14_N PF18027.1 GAX11924.1 - 9.8e-22 77.4 0.9 2e-21 76.4 0.9 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 GAX11924.1 - 1.2e-17 64.7 0.0 1.7e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Ammonium_transp PF00909.21 GAX11926.1 - 4.3e-108 361.5 24.4 4.9e-108 361.3 24.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 GAX11927.1 - 9.8e-111 370.3 30.4 1.1e-110 370.0 30.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family His_Phos_1 PF00300.22 GAX11928.1 - 2e-09 37.4 0.0 0.00047 19.9 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ion_trans_2 PF07885.16 GAX11929.1 - 1.5e-24 85.8 24.6 2.5e-13 49.8 8.4 2.5 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 GAX11929.1 - 0.0003 20.1 11.2 0.026 13.8 2.7 2.3 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 GAX11929.1 - 0.00089 19.1 0.3 0.0052 16.6 0.0 2.2 2 1 0 2 2 2 1 Ligand-gated ion channel RTA1 PF04479.13 GAX11929.1 - 0.029 14.0 2.2 0.049 13.2 0.5 1.9 2 0 0 2 2 2 0 RTA1 like protein IRK PF01007.20 GAX11929.1 - 0.052 13.4 5.7 1.6 8.6 0.2 2.9 2 1 1 3 3 3 0 Inward rectifier potassium channel transmembrane domain DUF2721 PF11026.8 GAX11929.1 - 0.11 12.4 1.5 16 5.4 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CDC45 PF02724.14 GAX11929.1 - 0.15 10.3 8.1 0.22 9.8 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 GAX11929.1 - 7.7 6.2 6.5 30 4.2 5.5 2.3 2 0 0 2 2 2 0 FAM176 family UTP15_C PF09384.10 GAX11930.1 - 3.5e-21 75.4 0.3 4e-20 72.0 0.1 2.3 2 0 0 2 2 2 1 UTP15 C terminal ANAPC4_WD40 PF12894.7 GAX11930.1 - 4e-06 27.0 0.1 2.7e-05 24.4 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX11930.1 - 0.00021 22.0 7.9 0.0037 18.1 0.1 5.5 6 1 0 6 6 6 1 WD domain, G-beta repeat Nup160 PF11715.8 GAX11930.1 - 0.00047 18.9 0.1 0.21 10.2 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 TPR_1 PF00515.28 GAX11932.1 - 0.017 14.9 1.2 6.6 6.7 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX11932.1 - 0.27 11.5 2.8 15 5.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 GAX11935.1 - 1.5e-72 244.2 0.0 2.1e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX11935.1 - 2.9e-33 115.3 0.0 4.4e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX11935.1 - 0.0001 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAX11935.1 - 0.0046 15.8 0.0 0.056 12.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAX11935.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NifU_N PF01592.16 GAX11935.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 NifU-like N terminal domain DKCLD PF08068.12 GAX11936.1 - 7.9e-32 109.1 1.8 1.5e-29 101.8 0.3 2.9 3 0 0 3 3 3 2 DKCLD (NUC011) domain TruB_N PF01509.18 GAX11936.1 - 1.5e-21 77.4 0.2 3.8e-19 69.5 0.2 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAX11936.1 - 4.9e-20 71.5 1.0 9.8e-20 70.5 1.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 GAX11936.1 - 5.6e-18 64.7 1.6 1e-17 63.8 1.6 1.5 1 0 0 1 1 1 1 PUA domain PDZ PF00595.24 GAX11937.1 - 3.7e-07 30.4 0.1 9e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX11937.1 - 0.0012 19.1 0.2 0.0036 17.6 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX11937.1 - 0.013 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain OTU PF02338.19 GAX11939.1 - 9.2e-16 58.5 0.0 1.9e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAX11939.1 - 0.00022 20.7 0.1 0.36 10.2 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain O-FucT PF10250.9 GAX11940.1 - 7.4e-06 25.9 0.3 1.7e-05 24.7 0.3 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DtxR PF18357.1 GAX11940.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain SRTM1 PF15872.5 GAX11940.1 - 0.48 10.6 1.9 1.2 9.4 1.9 1.6 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 DUF3798 PF12683.7 GAX11941.1 - 0.00038 20.0 0.9 7.9 5.8 0.0 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3798) BLYB PF05289.11 GAX11941.1 - 0.0017 18.6 10.2 2 8.7 0.1 4.4 4 0 0 4 4 4 3 Borrelia hemolysin accessory protein DUF5388 PF17363.2 GAX11941.1 - 0.002 18.3 0.1 1.7 8.9 0.1 4.5 4 0 0 4 4 4 1 Family of unknown function (DUF5388) Lentiviral_Tat PF02998.14 GAX11941.1 - 0.0049 16.9 0.0 24 5.0 0.0 4.6 4 0 0 4 4 4 0 Lentiviral Tat protein MutS_I PF01624.20 GAX11941.1 - 0.0062 16.8 0.0 90 3.4 0.0 5.3 6 0 0 6 6 6 0 MutS domain I DUF3461 PF11944.8 GAX11941.1 - 0.0065 16.6 0.0 0.4 10.8 0.0 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3461) DUF2574 PF10836.8 GAX11941.1 - 0.11 12.4 0.0 19 5.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2574) DUF4781 PF16013.5 GAX11941.1 - 0.62 8.8 4.9 3.9 6.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4781) PC-Esterase PF13839.6 GAX11942.1 - 5e-15 56.0 2.1 3.5e-08 33.5 0.1 4.5 2 1 1 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Sulfotransfer_3 PF13469.6 GAX11943.1 - 0.0028 18.1 0.0 0.0028 18.1 0.0 3.6 3 2 1 4 4 4 1 Sulfotransferase family BUD22 PF09073.10 GAX11944.1 - 0.21 10.9 20.7 0.42 9.9 20.7 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAX11944.1 - 0.23 9.6 21.6 0.37 8.9 21.6 1.2 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 GAX11944.1 - 2.1 7.0 11.6 3.6 6.3 11.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2457 PF10446.9 GAX11944.1 - 2.2 7.3 25.0 3.3 6.7 25.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF913 PF06025.12 GAX11944.1 - 5.2 5.9 8.0 9.7 5.1 8.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 GAX11944.1 - 5.9 5.0 17.3 9.5 4.4 17.3 1.3 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 GAX11944.1 - 7.1 5.7 13.4 14 4.7 13.4 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ferlin_C PF16165.5 GAX11945.1 - 0.24 11.4 2.2 0.48 10.3 2.2 1.5 1 0 0 1 1 1 0 Ferlin C-terminus SDA1 PF05285.12 GAX11945.1 - 6.9 6.0 18.2 10 5.4 18.2 1.3 1 0 0 1 1 1 0 SDA1 DUF1118 PF06549.12 GAX11946.1 - 2.9e-14 53.4 20.5 1.4e-07 31.9 3.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1118) LUC7 PF03194.15 GAX11947.1 - 4.2e-25 88.9 14.6 4e-22 79.1 12.4 2.5 2 1 0 2 2 2 2 LUC7 N_terminus BUD22 PF09073.10 GAX11947.1 - 0.0051 16.2 5.9 0.0064 15.9 5.9 1.2 1 0 0 1 1 1 1 BUD22 ALMT PF11744.8 GAX11947.1 - 0.042 12.7 7.1 0.055 12.3 7.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2347 PF09804.9 GAX11947.1 - 1.8 8.1 6.1 2 8.0 5.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) V_ATPase_I PF01496.19 GAX11947.1 - 4.8 5.0 9.9 6 4.7 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myb_DNA-binding PF00249.31 GAX11948.1 - 1.4e-29 102.0 11.7 1.2e-09 38.2 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX11948.1 - 5.9e-27 93.7 7.7 2.9e-15 56.2 0.4 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 GAX11948.1 - 0.12 12.5 2.1 3.2 7.9 0.3 2.9 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 GAX11948.1 - 0.19 11.9 1.4 25 5.2 0.1 2.7 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 PTH2 PF01981.16 GAX11949.1 - 1.6e-38 131.6 0.0 2e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TAXi_N PF14543.6 GAX11951.1 - 1.3e-16 61.4 6.3 1.3e-16 61.4 6.3 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX11951.1 - 1.2e-13 51.2 4.5 7.5e-06 25.6 0.1 3.1 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX11951.1 - 0.039 13.7 0.0 11 5.8 0.0 3.3 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal CDC73_C PF05179.14 GAX11952.1 - 1.1e-40 138.9 0.0 2.4e-40 137.8 0.0 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal HECT PF00632.25 GAX11953.1 - 8.3e-11 41.9 0.1 3.7e-10 39.8 0.1 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TetR_C_4 PF08359.11 GAX11953.1 - 0.17 12.0 2.1 10 6.2 0.1 2.6 2 0 0 2 2 2 0 YsiA-like protein, C-terminal region PspA_IM30 PF04012.12 GAX11953.1 - 0.67 9.5 7.5 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 PspA/IM30 family DUF3993 PF13158.6 GAX11953.1 - 4.2 7.6 6.1 3.4 7.9 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3993) Aminotran_3 PF00202.21 GAX11954.1 - 2e-72 244.1 0.1 2.6e-72 243.7 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III RWD PF05773.22 GAX11955.1 - 0.0083 16.4 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain DUF1330 PF07045.11 GAX11956.1 - 0.2 12.0 3.3 0.2 12.0 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1330) Rsa3 PF14615.6 GAX11957.1 - 1.1e-06 28.0 0.3 5.4e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 Ribosome-assembly protein 3 B12-binding PF02310.19 GAX11957.1 - 0.15 12.1 0.2 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 B12 binding domain vATP-synt_E PF01991.18 GAX11957.1 - 0.18 11.2 2.3 0.31 10.4 2.3 1.5 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit W2 PF02020.18 GAX11958.1 - 6e-13 48.7 1.6 1.5e-12 47.5 1.6 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 GAX11958.1 - 2.8e-11 42.7 11.4 6.2e-06 25.7 3.9 4.0 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAX11958.1 - 3.3e-08 34.0 0.3 7.1e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 GAX11958.1 - 3.4e-05 23.5 0.1 6.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 GAX11958.1 - 0.00017 19.9 1.8 0.00026 19.3 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GAX11958.1 - 4.7 7.0 16.2 5.8 6.7 0.5 3.5 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase SNF2_N PF00176.23 GAX11960.1 - 4.4e-77 259.1 0.2 1.1e-76 257.9 0.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAX11960.1 - 2.2e-27 95.3 0.2 2.2e-27 95.3 0.2 2.7 3 0 0 3 3 3 1 SLIDE Helicase_C PF00271.31 GAX11960.1 - 2.4e-20 72.9 0.0 1.6e-19 70.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX11960.1 - 8.3e-10 38.9 1.7 1.5e-09 38.1 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 GAX11960.1 - 4.1e-09 36.7 0.4 4.1e-09 36.7 0.4 3.5 4 0 0 4 4 4 1 HMG (high mobility group) box HDA2-3 PF11496.8 GAX11960.1 - 4.1e-08 32.7 0.0 1.4e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 HMG_box_2 PF09011.10 GAX11960.1 - 4.1e-07 30.5 0.5 4.1e-07 30.5 0.5 2.9 3 0 0 3 3 3 1 HMG-box domain Myb_DNA-binding PF00249.31 GAX11960.1 - 7e-05 22.9 0.0 0.0018 18.4 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain DEAD PF00270.29 GAX11960.1 - 0.00028 20.7 0.0 0.002 17.9 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAX11960.1 - 0.0046 16.2 0.1 0.0046 16.2 0.1 3.0 2 1 1 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase DUF3439 PF11921.8 GAX11961.1 - 0.00047 20.1 11.6 0.00089 19.2 11.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 GAX11961.1 - 0.18 9.8 10.2 0.23 9.4 10.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.11 GAX11961.1 - 0.25 9.4 3.9 0.27 9.3 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 GAX11961.1 - 0.52 8.5 16.1 0.7 8.0 16.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 GAX11961.1 - 1.5 8.8 26.9 3 7.8 26.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.6 GAX11961.1 - 5.3 6.9 7.1 8.5 6.3 7.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Brix PF04427.18 GAX11962.1 - 3.7e-37 128.3 0.1 5.2e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF1682 PF07946.14 GAX11962.1 - 0.037 13.2 7.0 0.067 12.4 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CCDC71L PF15374.6 GAX11962.1 - 0.081 12.2 6.5 0.15 11.3 6.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L MMADHC PF10229.9 GAX11962.1 - 0.72 9.6 3.8 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type D protein Spem1 PF15670.5 GAX11962.1 - 2.1 7.8 8.9 2.1 7.9 7.4 1.7 2 0 0 2 2 2 0 Spermatid maturation protein 1 MAJIN PF15077.6 GAX11962.1 - 4 7.2 7.3 7.9 6.2 7.3 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Iso_dh PF00180.20 GAX11963.1 - 5.7e-135 449.9 0.0 6.6e-135 449.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Troponin PF00992.20 GAX11964.1 - 1.6 9.0 8.2 4.1 7.7 1.8 3.2 1 1 1 2 2 2 0 Troponin VIT1 PF01988.19 GAX11966.1 - 7.1e-49 166.6 6.8 8e-49 166.4 6.8 1.0 1 0 0 1 1 1 1 VIT family Phage_Mu_Gam PF07352.12 GAX11966.1 - 0.0032 17.4 0.1 0.0043 17.0 0.1 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Pkinase PF00069.25 GAX11967.1 - 2.1e-09 37.1 0.0 1.2e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 GAX11967.1 - 4.6e-07 30.3 0.4 0.0056 17.3 0.0 5.1 4 2 1 5 5 5 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX11967.1 - 3.9e-06 27.0 0.4 0.0055 17.0 0.1 4.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX11967.1 - 7.1e-06 26.5 2.0 0.00091 19.8 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 GAX11967.1 - 0.0036 16.6 0.1 0.015 14.6 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 GAX11967.1 - 0.016 15.7 3.3 0.8 10.5 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat Ank PF00023.30 GAX11967.1 - 1.5 9.4 7.1 19 5.9 0.0 4.2 3 1 0 3 3 3 0 Ankyrin repeat CAP_N PF01213.19 GAX11968.1 - 1.6 8.2 11.6 3.8 6.9 11.6 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cnd2 PF05786.14 GAX11971.1 - 5.5e-82 276.7 49.3 6.3e-78 263.2 49.3 3.2 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GAX11971.1 - 1.5e-05 25.2 4.1 0.00018 21.7 4.1 2.9 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Glutaredoxin PF00462.24 GAX11972.1 - 3.9e-37 126.3 0.0 7.2e-18 64.6 0.0 2.8 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 GAX11972.1 - 7.7e-08 32.3 0.0 1.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin SH3BGR PF04908.15 GAX11972.1 - 1.6e-06 28.2 0.1 0.0067 16.6 0.0 3.1 3 0 0 3 3 3 2 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 GAX11972.1 - 0.00038 20.8 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Symplekin_C PF12295.8 GAX11972.1 - 0.028 14.5 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal OST3_OST6 PF04756.13 GAX11972.1 - 0.058 12.7 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RdRP PF05183.12 GAX11972.1 - 0.062 11.9 0.0 1.6 7.3 0.0 2.1 1 1 1 2 2 2 0 RNA dependent RNA polymerase Chor_lyase PF04345.13 GAX11972.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Chorismate lyase Thioredoxin_8 PF13905.6 GAX11972.1 - 0.12 12.7 0.0 3.2 8.2 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin-like DUF1033 PF06279.11 GAX11973.1 - 0.018 15.2 0.8 0.044 14.0 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Ion_trans_N PF08412.10 GAX11973.1 - 0.17 11.5 0.6 0.5 10.0 0.6 1.8 1 0 0 1 1 1 0 Ion transport protein N-terminal BEX PF04538.12 GAX11973.1 - 2.6 8.7 9.9 1.7e+02 2.8 10.0 2.6 1 1 0 1 1 1 0 Brain expressed X-linked like family HSP70 PF00012.20 GAX11974.1 - 5.1e-87 292.5 0.6 4.7e-86 289.3 0.6 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX11974.1 - 1.3e-15 57.1 0.3 3.5e-11 42.5 0.0 3.2 3 0 0 3 3 3 3 MreB/Mbl protein BcrAD_BadFG PF01869.20 GAX11974.1 - 7.2e-07 29.0 0.1 1.9e-05 24.3 0.0 2.3 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 GAX11974.1 - 0.0048 16.2 0.7 0.04 13.2 0.0 2.4 3 0 0 3 3 3 1 StbA protein DDR PF08841.10 GAX11974.1 - 0.017 14.1 0.3 0.94 8.4 0.0 2.7 2 1 1 3 3 3 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 GAX11974.1 - 0.037 14.4 0.0 0.6 10.6 0.0 2.8 2 2 0 2 2 2 0 Cell division protein FtsA Histidinol_dh PF00815.20 GAX11974.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase Rieske PF00355.26 GAX11975.1 - 7.7e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 GAX11975.1 - 3e-10 40.4 0.3 5.5e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region PAH PF02671.21 GAX11976.1 - 0.15 12.2 0.2 49 4.2 0.0 3.6 4 0 0 4 4 4 0 Paired amphipathic helix repeat DUF547 PF04784.14 GAX11977.1 - 5.8e-26 90.9 0.0 1.2e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF547 PH PF00169.29 GAX11977.1 - 3.3e-06 27.5 0.1 1.1e-05 25.9 0.1 1.9 1 0 0 1 1 1 1 PH domain Peptidase_U32_C PF16325.5 GAX11977.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain FAD_binding_4 PF01565.23 GAX11978.1 - 2.5e-22 79.1 0.0 6.1e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 GAX11978.1 - 2.6e-18 66.8 6.9 6.7e-18 65.4 3.2 2.7 2 1 0 2 2 2 1 D-arabinono-1,4-lactone oxidase DUF1281 PF06924.11 GAX11978.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) HMG_box_5 PF14887.6 GAX11979.1 - 0.1 12.6 0.4 0.1 12.6 0.4 2.9 4 0 0 4 4 4 0 HMG (high mobility group) box 5 TPR_1 PF00515.28 GAX11979.1 - 0.16 11.8 0.9 4.6 7.2 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX11979.1 - 0.65 10.0 2.6 4.5 7.3 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat EGF PF00008.27 GAX11980.1 - 1.8e-10 41.0 34.4 1e-05 25.7 7.6 3.8 3 1 0 3 3 3 3 EGF-like domain EGF_2 PF07974.13 GAX11980.1 - 2.9e-05 24.4 41.9 0.012 15.9 11.6 3.5 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 GAX11980.1 - 0.041 14.5 31.8 0.29 11.8 2.9 5.2 5 2 0 5 5 5 0 Human growth factor-like EGF CbtA PF09490.10 GAX11980.1 - 0.79 9.4 2.2 1.3 8.7 2.2 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Laminin_EGF PF00053.24 GAX11980.1 - 6.3 7.0 34.8 29 4.9 12.3 3.7 1 1 2 3 3 3 0 Laminin EGF domain Homeobox_KN PF05920.11 GAX11981.1 - 3.2e-10 39.7 0.0 9.2e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAX11981.1 - 0.00029 20.6 0.3 0.00064 19.5 0.3 1.6 1 0 0 1 1 1 1 Homeodomain Methyltransf_15 PF09445.10 GAX11982.1 - 1.4e-23 83.3 0.0 1.6e-21 76.6 0.0 2.4 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 GAX11982.1 - 0.00051 19.7 0.0 0.054 13.1 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 GAX11982.1 - 0.00051 20.7 0.0 0.0014 19.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 GAX11982.1 - 0.0056 15.7 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 GAX11982.1 - 0.0079 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAX11982.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 GAX11982.1 - 0.044 13.5 0.3 1.4 8.6 0.3 2.7 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF4116 PF13475.6 GAX11984.1 - 1.5e-26 91.9 0.6 1.4e-06 27.9 0.1 10.2 8 3 2 10 10 10 8 Domain of unknown function (DUF4116) FlaF PF07309.11 GAX11984.1 - 0.1 12.6 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 Flagellar protein FlaF Arm-DNA-bind_5 PF17293.2 GAX11984.1 - 0.64 10.5 2.4 0.93 10.0 1.2 1.9 2 0 0 2 2 2 0 Arm DNA-binding domain AOX PF01786.17 GAX11985.1 - 4.3e-25 88.6 0.9 6.3e-25 88.0 0.9 1.2 1 0 0 1 1 1 1 Alternative oxidase Ntox46 PF15538.6 GAX11985.1 - 0.071 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial toxin 46 Ribosomal_L14 PF00238.19 GAX11986.1 - 5.5e-34 116.9 0.2 7.3e-34 116.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Calreticulin PF00262.18 GAX11987.1 - 5.9e-88 295.2 12.4 3.1e-64 217.2 2.6 2.1 1 1 1 2 2 2 2 Calreticulin family DnaJ_CXXCXGXG PF00684.19 GAX11989.1 - 0.025 14.9 9.5 0.055 13.8 9.5 1.6 1 0 0 1 1 1 0 DnaJ central domain Anti-TRAP PF15777.5 GAX11989.1 - 0.1 12.6 6.3 0.21 11.5 6.3 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein INSIG PF07281.12 GAX11989.1 - 0.13 11.9 3.2 7.2 6.2 0.1 2.5 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) Zn_Tnp_IS1595 PF12760.7 GAX11989.1 - 4.4 7.4 6.1 2.6 8.1 3.4 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain ADD_ATRX PF17981.1 GAX11989.1 - 7.3 6.5 6.0 12 5.8 0.2 3.1 3 0 0 3 3 3 0 Cysteine Rich ADD domain CBFD_NFYB_HMF PF00808.23 GAX11990.1 - 5.1e-17 61.9 2.0 3.5e-12 46.4 0.3 2.4 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX11990.1 - 1.4e-12 48.1 1.6 2.6e-12 47.2 1.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAX11990.1 - 0.025 14.8 1.7 0.027 14.6 0.2 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) CENP-X PF09415.10 GAX11990.1 - 0.027 14.8 0.2 0.059 13.7 0.2 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Auxin_canalis PF05703.11 GAX11990.1 - 0.17 11.8 4.8 0.027 14.4 1.2 1.5 2 0 0 2 2 2 0 Auxin canalisation DUF1732 PF08340.11 GAX11990.1 - 0.23 11.5 1.5 7.6 6.6 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1732) Beta_elim_lyase PF01212.21 GAX11991.1 - 3.5e-79 266.1 0.0 4.6e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAX11991.1 - 4.5e-06 26.1 0.0 8.1e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II NSP16 PF06460.12 GAX11991.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 HIG_1_N PF04588.13 GAX11992.1 - 8.2e-19 67.6 0.4 1.1e-18 67.2 0.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region NIF PF03031.18 GAX11993.1 - 2e-52 177.1 0.0 2.6e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase O-antigen_lig PF13425.6 GAX11994.1 - 1.1 8.0 5.9 0.26 10.0 0.4 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Pox_A14 PF05767.12 GAX11994.1 - 4.9 7.4 8.6 0.4 10.9 0.3 3.1 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 bZIP_1 PF00170.21 GAX11995.1 - 0.00015 21.8 9.0 0.00015 21.8 9.0 3.0 3 1 1 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 GAX11995.1 - 0.00056 19.9 5.5 0.00056 19.9 5.5 3.8 4 0 0 4 4 4 2 Basic region leucine zipper DUF2009 PF09418.10 GAX11995.1 - 0.0055 15.8 1.0 0.0063 15.6 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) DUF3492 PF11997.8 GAX11995.1 - 0.03 14.1 0.8 0.039 13.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Enkurin PF13864.6 GAX11995.1 - 0.38 11.2 6.0 0.2 12.1 3.1 1.9 1 1 1 2 2 2 0 Calmodulin-binding bZIP_Maf PF03131.17 GAX11995.1 - 0.53 10.8 14.6 0.11 13.1 9.8 2.3 1 1 0 2 2 2 0 bZIP Maf transcription factor Cullin PF00888.22 GAX11996.1 - 7.1e-85 285.9 1.2 2.9e-77 260.7 0.1 2.3 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 GAX11996.1 - 4.3e-21 74.7 1.2 3.2e-20 71.9 1.2 2.6 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF1366 PF07104.11 GAX11996.1 - 1.4 8.6 3.7 25 4.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) 4HBT_2 PF13279.6 GAX11997.1 - 2.2e-13 50.8 0.1 2.9e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAX11997.1 - 0.00047 20.4 0.1 0.0015 18.9 0.1 1.8 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 GAX11997.1 - 0.098 11.9 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Acyl-ACP thioesterase Glyoxalase_3 PF13468.6 GAX11999.1 - 5.1e-27 95.1 0.0 7.1e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 GAX11999.1 - 0.00019 21.7 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AA_kinase PF00696.28 GAX12000.1 - 1.4e-11 44.5 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 GAX12000.1 - 5.3e-05 23.4 0.1 0.00011 22.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX12000.1 - 7.5e-05 22.7 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX12000.1 - 0.00023 21.5 0.2 0.00058 20.2 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PRAS PF15798.5 GAX12001.1 - 0.041 14.5 0.9 0.13 12.9 0.9 1.8 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 DUF4585 PF15232.6 GAX12001.1 - 0.059 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Proteasome PF00227.26 GAX12002.1 - 2.3e-32 112.1 0.0 3.3e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit rve PF00665.26 GAX12003.1 - 2.5e-10 40.6 0.0 6.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GAX12003.1 - 3e-09 36.9 0.1 1.4e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain gag_pre-integrs PF13976.6 GAX12003.1 - 0.0025 17.6 0.1 0.0089 15.9 0.1 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain Aa_trans PF01490.18 GAX12004.1 - 6e-63 213.0 18.1 9.8e-63 212.2 18.1 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 GAX12004.1 - 0.79 10.2 11.2 22 5.6 1.1 4.4 3 2 1 4 4 4 0 Domain of unknown function (DUF202) Exop_C PF18559.1 GAX12005.1 - 0.0088 15.9 1.7 0.4 10.5 0.2 2.3 1 1 1 2 2 2 2 Galactose-binding domain-like 3HCDH_RFF PF18321.1 GAX12005.1 - 4.2 7.9 11.7 89 3.6 0.3 4.3 4 0 0 4 4 4 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain APG5 PF04106.12 GAX12007.1 - 1.1e-30 106.9 0.0 1.6e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 Mito_carr PF00153.27 GAX12008.1 - 5.6e-51 170.4 2.0 6.4e-18 64.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M61 PF05299.12 GAX12008.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 M61 glycyl aminopeptidase Romo1 PF10247.9 GAX12008.1 - 0.1 13.0 1.0 3 8.3 0.1 3.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Cnd1 PF12717.7 GAX12009.1 - 4.2e-49 166.7 8.9 2.3e-46 157.8 0.2 4.5 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX12009.1 - 0.0019 18.3 3.9 10 6.7 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 GAX12009.1 - 0.012 16.1 0.0 1.5 9.4 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat RTP1_C1 PF10363.9 GAX12009.1 - 0.065 13.4 3.1 11 6.2 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 hnRNP_Q_AcD PF18360.1 GAX12011.1 - 2.7e-32 110.5 0.0 2.7e-16 59.3 0.0 3.5 3 0 0 3 3 3 3 Heterogeneous nuclear ribonucleoprotein Q acidic domain WD40 PF00400.32 GAX12012.1 - 1.4e-19 70.0 14.6 0.00018 22.2 0.0 7.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Hira PF07569.11 GAX12012.1 - 3.1e-12 46.7 0.1 3.1e-11 43.4 0.0 2.7 2 1 0 2 2 2 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 GAX12012.1 - 4.9e-10 39.6 0.0 0.58 10.5 0.0 6.9 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Thioredoxin PF00085.20 GAX12013.1 - 4.2e-24 84.5 0.0 7.5e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX12013.1 - 5.3e-07 30.1 0.1 1.3e-05 25.6 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX12013.1 - 4.4e-05 23.7 0.0 0.019 15.3 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like SAP PF02037.27 GAX12013.1 - 7.5e-05 22.4 3.1 0.13 12.1 0.0 4.1 4 0 0 4 4 4 2 SAP domain Thioredoxin_7 PF13899.6 GAX12013.1 - 0.00021 21.4 0.0 0.00077 19.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 GAX12013.1 - 0.0027 17.4 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Redoxin TraF PF13728.6 GAX12013.1 - 0.0048 16.8 0.1 0.0095 15.8 0.0 1.6 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GAX12013.1 - 0.0085 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 GAX12013.1 - 0.012 15.6 0.0 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family OST3_OST6 PF04756.13 GAX12013.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 GAX12013.1 - 0.015 15.3 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.11 GAX12013.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DSBA PF01323.20 GAX12013.1 - 0.19 11.5 0.6 3.2 7.5 0.0 2.7 1 1 2 3 3 3 0 DSBA-like thioredoxin domain Aa_trans PF01490.18 GAX12014.1 - 4.6e-08 32.2 4.6 4.6e-08 32.2 4.6 3.2 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 GAX12014.1 - 0.041 13.9 1.7 0.062 13.3 0.8 1.8 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Ank_4 PF13637.6 GAX12015.1 - 2.1e-06 28.1 0.2 0.015 15.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX12015.1 - 0.00019 21.7 0.0 0.0011 19.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX12015.1 - 0.0015 19.1 0.0 0.004 17.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX12015.1 - 0.014 15.9 0.1 6.8 7.6 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat MADF_DNA_bdg PF10545.9 GAX12016.1 - 0.2 12.0 1.0 0.47 10.8 0.2 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MSC PF09402.10 GAX12016.1 - 0.23 10.9 7.8 0.67 9.3 1.7 2.3 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Pyr_redox_2 PF07992.14 GAX12017.1 - 3.9e-52 177.3 3.6 5.2e-52 176.9 3.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX12017.1 - 1.9e-28 98.9 0.4 1e-27 96.5 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX12017.1 - 4.4e-13 49.6 1.7 1.1e-12 48.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX12017.1 - 1.6e-05 24.2 7.3 4.5e-05 22.7 1.7 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAX12017.1 - 6e-05 22.3 5.2 0.049 12.7 1.8 2.7 2 1 1 3 3 3 2 FAD binding domain 3HCDH_N PF02737.18 GAX12017.1 - 0.00025 21.0 1.0 0.28 11.0 0.0 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAX12017.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 GAX12017.1 - 0.074 12.4 1.7 0.13 11.6 1.7 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX12017.1 - 0.26 11.6 6.4 32 4.9 4.5 3.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain zf-RING_6 PF14835.6 GAX12018.1 - 0.0041 17.0 8.2 0.0086 15.9 8.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 GAX12018.1 - 0.0057 16.6 17.5 0.0099 15.8 17.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF1272 PF06906.11 GAX12018.1 - 0.021 14.9 14.6 0.044 13.9 14.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.6 GAX12018.1 - 0.23 11.4 12.5 0.49 10.3 12.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 GAX12018.1 - 0.34 10.2 3.9 0.59 9.4 3.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_2 PF13639.6 GAX12018.1 - 0.4 11.1 16.8 0.7 10.3 16.2 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 GAX12018.1 - 0.8 9.6 16.0 0.16 11.8 12.6 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf_UBZ PF18439.1 GAX12018.1 - 8.4 6.1 11.4 2.7 7.7 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Glyco_hydro_31 PF01055.26 GAX12020.1 - 0.028 13.6 0.2 0.044 13.0 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 31 Hamartin PF04388.12 GAX12022.1 - 1.8 7.1 29.6 2.1 6.9 29.6 1.0 1 0 0 1 1 1 0 Hamartin protein CBM_6 PF03422.15 GAX12023.1 - 4.1e-71 237.1 11.9 3.6e-21 75.8 0.0 5.2 5 0 0 5 5 5 5 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX12023.1 - 3.1e-40 136.8 6.2 1.1e-07 32.0 0.1 5.3 5 0 0 5 5 5 5 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX12023.1 - 1.2e-14 54.5 9.7 0.027 14.7 0.0 5.8 5 1 0 5 5 5 5 Carbohydrate binding module (family 35) Endotoxin_C PF03944.14 GAX12023.1 - 3.6e-06 27.4 0.2 0.67 10.3 0.0 4.8 5 0 0 5 5 5 2 delta endotoxin GH115_C PF17829.1 GAX12023.1 - 0.0015 18.4 0.2 6.4 6.6 0.0 4.8 5 1 0 5 5 5 1 Gylcosyl hydrolase family 115 C-terminal domain Gly_acyl_tr_C PF08444.10 GAX12023.1 - 0.0083 16.3 0.2 24 5.3 0.0 3.9 4 0 0 4 4 4 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acyltransferase PF01553.21 GAX12024.1 - 1.2e-12 47.6 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CBM_6 PF03422.15 GAX12025.1 - 2.8e-37 127.8 7.5 8.7e-17 61.6 0.0 4.0 4 0 0 4 4 4 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX12025.1 - 2.5e-20 72.7 1.8 1.2e-07 31.9 0.0 3.6 4 0 0 4 4 4 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX12025.1 - 8.2e-06 26.1 0.3 0.068 13.4 0.0 3.7 3 1 0 3 3 3 2 Carbohydrate binding module (family 35) CBM_6 PF03422.15 GAX12026.1 - 1.4e-38 132.0 2.8 1.8e-14 54.1 0.3 3.1 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX12026.1 - 5e-20 71.7 1.4 1.6e-08 34.6 0.1 3.3 3 0 0 3 3 3 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX12026.1 - 3.5e-07 30.5 2.0 0.13 12.5 0.0 3.8 3 1 0 3 3 3 3 Carbohydrate binding module (family 35) Rib PF08428.10 GAX12026.1 - 0.021 14.8 0.1 3.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Rib/alpha-like repeat TIM PF00121.18 GAX12029.1 - 1.6e-82 276.5 0.0 2.4e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase Gp_dh_C PF02800.20 GAX12029.1 - 9.8e-69 230.0 0.0 2.9e-68 228.4 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX12029.1 - 6.7e-34 116.3 0.0 1.7e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX12029.1 - 0.013 15.6 0.0 0.049 13.7 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 GAX12029.1 - 0.028 13.8 0.0 0.091 12.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Response_reg PF00072.24 GAX12030.1 - 3.3e-25 88.4 0.9 3.9e-20 72.1 0.1 3.0 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 GAX12030.1 - 8.1e-07 29.0 0.2 2.9e-06 27.2 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4634 PF15465.6 GAX12030.1 - 0.56 10.5 2.0 15 5.9 0.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4634) HMG_box PF00505.19 GAX12031.1 - 0.00038 20.8 5.0 0.00073 19.9 5.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX12031.1 - 0.0041 17.7 4.4 0.0081 16.7 4.4 1.5 1 0 0 1 1 1 1 HMG-box domain DEAD PF00270.29 GAX12033.1 - 1.3e-14 54.4 0.0 4.4e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4471 PF14740.6 GAX12033.1 - 0.0014 17.9 2.1 0.0014 17.9 2.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4471) Helicase_C PF00271.31 GAX12033.1 - 0.054 13.8 0.1 0.45 10.9 0.1 2.6 1 1 0 1 1 1 0 Helicase conserved C-terminal domain RNase_PH PF01138.21 GAX12034.1 - 2.4e-31 109.0 0.1 4.2e-31 108.2 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TAL_FSA PF00923.19 GAX12035.1 - 1e-26 94.0 0.0 8.1e-26 91.0 0.0 1.9 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase ILVD_EDD PF00920.21 GAX12035.1 - 0.069 11.8 0.1 0.12 10.9 0.1 1.3 2 0 0 2 2 2 0 Dehydratase family Carb_kinase PF01256.17 GAX12036.1 - 1.8e-42 145.5 0.1 2.7e-42 144.9 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase PIP5K PF01504.18 GAX12037.1 - 1e-63 215.1 0.0 2.5e-63 213.9 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Acetyltransf_1 PF00583.25 GAX12038.1 - 2.8e-10 40.5 0.0 3.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX12038.1 - 1.5e-09 37.8 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX12038.1 - 2.6e-08 34.2 0.0 4.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX12038.1 - 1.3e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAX12038.1 - 0.0046 17.0 0.1 0.0085 16.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 GAX12038.1 - 0.008 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.7 GAX12038.1 - 0.026 14.7 0.1 0.036 14.2 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAX12038.1 - 0.07 12.6 1.0 0.11 11.9 1.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Rol_Rep_N PF18106.1 GAX12040.1 - 0.014 15.7 0.1 0.035 14.4 0.1 1.7 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain OmpH PF03938.14 GAX12040.1 - 3.6 7.9 18.1 0.4 11.0 5.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.6 GAX12040.1 - 4.8 7.4 21.9 0.099 12.8 11.4 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit UPF0016 PF01169.19 GAX12042.1 - 6.7e-45 151.3 16.2 6.4e-24 84.1 3.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 EF-hand_5 PF13202.6 GAX12042.1 - 9.9e-08 31.2 0.1 2.2e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GAX12042.1 - 1.4e-05 24.3 0.1 2.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX12042.1 - 4.3e-05 23.1 0.1 8.9e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAX12042.1 - 8.1e-05 23.0 0.1 0.00024 21.5 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair OFeT_1 PF16955.5 GAX12042.1 - 0.00024 20.8 0.2 0.00059 19.6 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron uptake permease, iron-lead transporter SpoIIM PF01944.17 GAX12042.1 - 0.0013 18.7 1.0 0.0036 17.4 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein M EF-hand_8 PF13833.6 GAX12042.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair ubiquitin PF00240.23 GAX12043.1 - 2.4e-06 27.2 0.4 5.9e-06 25.9 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 GAX12043.1 - 0.0011 19.4 0.1 0.0049 17.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 GAX12043.1 - 0.037 13.8 0.4 0.34 10.8 0.4 2.0 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like EF-hand_7 PF13499.6 GAX12044.1 - 4.9e-08 33.3 0.2 0.14 12.6 0.0 5.6 6 1 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 GAX12044.1 - 5.6e-07 28.7 1.4 0.29 10.8 0.0 5.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAX12044.1 - 1.7e-06 27.4 2.3 0.21 11.6 0.0 5.8 5 0 0 5 5 5 2 EF-hand domain RelA_SpoT PF04607.17 GAX12045.1 - 5.5e-18 65.3 0.0 3.3e-17 62.9 0.0 2.2 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 GAX12045.1 - 1.1e-05 25.3 0.3 4.8e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 HD domain Ribosomal_L6 PF00347.23 GAX12046.1 - 8.5e-27 93.6 0.1 1.2e-11 45.2 0.1 3.1 3 0 0 3 3 3 3 Ribosomal protein L6 VIT1 PF01988.19 GAX12047.1 - 1.3e-59 201.7 0.1 1.6e-59 201.4 0.1 1.1 1 0 0 1 1 1 1 VIT family Bromodomain PF00439.25 GAX12049.1 - 2.8e-15 56.2 0.0 9.6e-15 54.4 0.0 2.0 2 0 0 2 2 2 1 Bromodomain CLTH PF10607.9 GAX12049.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Imm31 PF15591.6 GAX12049.1 - 0.19 11.6 0.0 0.73 9.7 0.1 2.0 2 0 0 2 2 2 0 Immunity protein 31 TPR_17 PF13431.6 GAX12050.1 - 0.13 12.7 0.0 32 5.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HATPase_c PF02518.26 GAX12051.1 - 2e-29 102.3 0.1 3.6e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX12051.1 - 9.3e-24 83.8 0.1 2.3e-23 82.5 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX12051.1 - 6.6e-16 58.1 0.0 2.3e-15 56.4 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 GAX12051.1 - 1.6e-05 25.1 0.0 0.014 15.7 0.0 2.9 2 1 0 2 2 2 2 PAS fold PAS_9 PF13426.7 GAX12051.1 - 0.00053 20.2 0.0 1.8 8.8 0.0 2.9 2 0 0 2 2 2 2 PAS domain HATPase_c_3 PF13589.6 GAX12051.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 GAX12052.1 - 1.8e-41 142.3 0.0 8.9e-31 107.2 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12052.1 - 2.3e-16 59.9 0.0 1.2e-15 57.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX12052.1 - 0.0098 15.2 0.4 0.95 8.7 0.2 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 GAX12052.1 - 0.066 13.1 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2418 PF10332.9 GAX12052.1 - 0.098 13.2 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) VHP PF02209.19 GAX12053.1 - 3.7e-14 52.5 4.0 3.7e-14 52.5 4.0 3.2 4 0 0 4 4 4 1 Villin headpiece domain HEAT_2 PF13646.6 GAX12054.1 - 8e-05 22.9 0.2 0.021 15.2 0.1 3.4 2 1 0 2 2 2 1 HEAT repeats Arm PF00514.23 GAX12054.1 - 0.027 14.5 3.2 33 4.7 0.2 5.2 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat SLED PF12140.8 GAX12054.1 - 0.027 15.0 0.3 0.23 12.0 0.1 2.6 1 1 1 2 2 2 0 SLED domain DUF1539 PF07560.11 GAX12054.1 - 0.03 14.4 4.1 0.41 10.7 0.2 4.0 3 2 1 4 4 4 0 Domain of Unknown Function (DUF1539) TAFH PF07531.14 GAX12054.1 - 0.075 13.2 5.2 14 5.9 0.0 4.5 4 1 0 4 4 4 0 NHR1 homology to TAF NEL PF14496.6 GAX12054.1 - 0.1 12.0 2.3 0.37 10.2 0.4 2.8 3 1 0 3 3 3 0 C-terminal novel E3 ligase, LRR-interacting DUF3385 PF11865.8 GAX12054.1 - 0.24 11.3 12.2 0.33 10.8 0.0 4.5 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) DUF3636 PF12331.8 GAX12054.1 - 0.72 9.7 6.9 0.73 9.7 0.4 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3636) Baculo_PEP_C PF04513.12 GAX12054.1 - 1.6 8.8 5.1 0.61 10.1 1.4 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_1 PF00036.32 GAX12055.1 - 1.5e-05 24.2 1.4 0.13 11.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX12055.1 - 7.8e-05 22.3 0.2 0.0045 16.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 GAX12055.1 - 0.00025 21.4 0.3 0.00077 19.9 0.2 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAX12055.1 - 0.018 14.6 0.9 0.078 12.5 0.0 2.3 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 GAX12055.1 - 0.055 13.8 0.5 0.055 13.8 0.5 1.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region OTU PF02338.19 GAX12057.1 - 3.9e-16 59.7 0.0 6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease SEC-C PF02810.15 GAX12057.1 - 2.7e-08 33.6 3.9 7e-08 32.2 3.9 1.8 1 0 0 1 1 1 1 SEC-C motif RRM_1 PF00076.22 GAX12058.1 - 1.4e-77 255.5 0.9 5.5e-21 74.2 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAX12058.1 - 1.3e-31 108.6 0.3 5.1e-30 103.5 0.6 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAX12058.1 - 2.8e-05 23.7 0.0 0.66 9.6 0.0 3.5 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX12058.1 - 0.0012 18.9 0.1 16 5.7 0.0 4.0 3 1 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 GAX12058.1 - 0.0026 17.7 0.1 7.4 6.7 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RGP PF03214.13 GAX12058.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide DUF2960 PF11173.8 GAX12058.1 - 0.15 12.6 0.0 8.6 6.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) KH_1 PF00013.29 GAX12059.1 - 3.1e-44 148.6 11.0 3.3e-15 55.7 1.9 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAX12059.1 - 2e-11 43.6 9.1 0.00051 19.8 0.1 3.6 4 0 0 4 4 4 3 KH domain WW PF00397.26 GAX12059.1 - 4.7e-10 39.4 2.0 9.9e-10 38.3 2.0 1.6 1 0 0 1 1 1 1 WW domain KH_4 PF13083.6 GAX12059.1 - 3.1e-08 33.4 7.0 0.045 13.6 0.7 3.6 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 GAX12059.1 - 4.5e-06 26.6 0.1 0.024 14.6 0.0 2.8 3 0 0 3 3 3 2 KH-like RNA-binding domain SASP PF00269.20 GAX12059.1 - 0.0095 15.9 0.0 5.2 7.2 0.0 3.0 2 0 0 2 2 2 2 Small, acid-soluble spore proteins, alpha/beta type KH_5 PF13184.6 GAX12059.1 - 0.097 12.8 4.6 5.8 7.1 0.2 3.3 3 0 0 3 3 3 0 NusA-like KH domain PQQ PF01011.21 GAX12059.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat PAP_assoc PF03828.19 GAX12060.1 - 4e-12 46.2 0.7 7.7e-12 45.2 0.7 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAX12060.1 - 2.5e-11 43.7 0.2 6.9e-11 42.3 0.2 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAX12060.1 - 7.5e-05 22.7 0.0 0.00023 21.2 0.0 1.8 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase IQ PF00612.27 GAX12061.1 - 3.5e-18 63.6 32.9 0.002 17.8 0.3 7.9 7 0 0 7 7 7 7 IQ calmodulin-binding motif 7TMR-HDED PF07697.11 GAX12062.1 - 0.0021 18.2 4.6 0.0046 17.1 4.6 1.6 1 0 0 1 1 1 1 7TM-HD extracellular LPD37 PF18853.1 GAX12062.1 - 0.038 13.6 0.8 0.07 12.7 0.8 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 37 SPATA24 PF15175.6 GAX12062.1 - 0.1 12.5 8.0 0.24 11.3 8.0 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4071 PF13281.6 GAX12062.1 - 0.35 9.9 3.6 0.57 9.2 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) LPP PF04728.13 GAX12062.1 - 0.67 10.4 5.2 2.1 8.8 0.4 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Phlebovirus_NSM PF07246.11 GAX12062.1 - 0.78 9.1 6.4 1.3 8.3 6.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M OmpH PF03938.14 GAX12062.1 - 3.8 7.8 9.0 11 6.3 9.0 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Vpu PF00558.19 GAX12064.1 - 0.47 10.2 1.9 0.53 10.1 0.2 1.9 2 0 0 2 2 2 0 Vpu protein PGF-CTERM PF18204.1 GAX12065.1 - 0.047 13.7 4.6 0.12 12.3 4.6 1.8 1 0 0 1 1 1 0 PGF-CTERM motif C2 PF00168.30 GAX12066.1 - 0.00019 21.7 0.0 0.00049 20.4 0.0 1.7 2 0 0 2 2 2 1 C2 domain PCRF PF03462.18 GAX12067.1 - 9.5e-38 130.0 0.7 2.6e-37 128.6 0.1 2.0 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAX12067.1 - 1.8e-34 118.1 1.1 1.8e-34 118.1 1.1 1.7 2 0 0 2 2 2 1 RF-1 domain Helicase_C PF00271.31 GAX12068.1 - 1.3e-10 41.6 0.0 2.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX12068.1 - 9.3e-07 28.8 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX12068.1 - 1.4e-06 28.6 0.0 2.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX12068.1 - 0.0018 18.6 0.1 0.0038 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX12068.1 - 0.0019 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 GAX12068.1 - 0.004 17.1 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 GAX12068.1 - 0.008 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GAX12068.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 GAX12068.1 - 0.035 13.5 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 GAX12068.1 - 0.035 13.5 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 GAX12068.1 - 0.049 13.6 0.0 8.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 GAX12068.1 - 0.069 13.2 0.0 2.8 8.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain GalBD_like PF17974.1 GAX12068.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Galactose-binding domain-like Ribosomal_S13 PF00416.22 GAX12069.1 - 1e-47 161.7 0.5 1.1e-47 161.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 GAX12069.1 - 0.099 13.1 0.7 0.17 12.4 0.7 1.3 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 IMS_HHH PF11798.8 GAX12069.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif UVR PF02151.19 GAX12069.1 - 0.12 12.1 1.2 0.21 11.4 1.2 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif MRP-S33 PF08293.11 GAX12070.1 - 4.2e-06 26.9 0.6 6.2e-06 26.4 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 HSF_DNA-bind PF00447.17 GAX12071.1 - 1.1e-19 70.9 0.0 2.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4533 PF15047.6 GAX12071.1 - 0.041 13.4 0.3 0.081 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) URO-D PF01208.17 GAX12072.1 - 1.3e-74 251.4 0.0 1.6e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) HSF_DNA-bind PF00447.17 GAX12074.1 - 1.2e-19 70.7 0.0 2.6e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 GAX12075.1 - 1.4e-21 76.9 0.0 2.2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ovate PF04844.13 GAX12076.1 - 0.09 12.8 0.1 0.97 9.5 0.0 2.4 2 0 0 2 2 2 0 Transcriptional repressor, ovate Dioxygenase_C PF00775.21 GAX12076.1 - 0.13 11.7 0.1 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Dioxygenase Myc_target_1 PF15179.6 GAX12076.1 - 0.33 10.8 4.8 1.2 9.0 4.8 2.0 1 0 0 1 1 1 0 Myc target protein 1 RRM_1 PF00076.22 GAX12077.1 - 1.1e-06 28.4 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smr PF01713.21 GAX12078.1 - 4.1e-12 46.3 0.3 1.1e-11 44.9 0.1 1.9 2 0 0 2 2 2 1 Smr domain DUF3236 PF11576.8 GAX12078.1 - 1.4 8.6 4.3 9.6 5.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) GCK PF07802.11 GAX12078.1 - 3.2 8.2 7.8 0.27 11.7 1.3 2.6 2 1 1 3 3 3 0 GCK domain DUF2358 PF10184.9 GAX12079.1 - 3.5e-15 56.3 0.0 7.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SOUL PF04832.12 GAX12079.1 - 3.2e-14 53.5 0.0 7.5e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 SOUL heme-binding protein SnoaL_2 PF12680.7 GAX12079.1 - 0.17 12.5 0.0 0.51 11.0 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like domain Thioredoxin PF00085.20 GAX12080.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin TerB PF05099.13 GAX12080.1 - 0.03 14.3 1.4 0.051 13.5 1.4 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB Phosducin PF02114.16 GAX12080.1 - 0.041 12.8 0.1 0.064 12.2 0.1 1.4 1 0 0 1 1 1 0 Phosducin TraF PF13728.6 GAX12080.1 - 0.074 12.9 0.0 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 GAX12080.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain zf-RING_2 PF13639.6 GAX12081.1 - 3.1e-10 40.2 12.4 4.9e-10 39.6 12.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX12081.1 - 1.5e-07 31.6 8.6 2.6e-07 30.8 8.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX12081.1 - 5.2e-07 29.4 11.9 8.2e-07 28.8 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX12081.1 - 4.6e-06 26.4 11.0 8.1e-06 25.6 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX12081.1 - 1.8e-05 24.5 11.8 2.6e-05 24.0 11.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX12081.1 - 0.00044 20.1 12.4 0.00078 19.3 12.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAX12081.1 - 0.0011 18.9 14.8 0.0017 18.3 14.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX12081.1 - 0.01 15.8 12.3 0.022 14.8 12.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAX12081.1 - 0.017 15.3 12.7 0.023 14.8 6.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAX12081.1 - 0.095 12.8 5.2 0.17 12.0 5.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 GAX12081.1 - 0.98 9.2 8.7 1.8 8.4 8.7 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 GAX12081.1 - 1.5 9.0 6.2 3.1 8.0 6.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 GAX12081.1 - 1.8 8.5 7.8 3.4 7.6 7.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GAX12081.1 - 3.7 7.7 8.5 6.9 6.9 8.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 GAX12081.1 - 8.5 6.1 10.2 14 5.4 10.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type MTHFR PF02219.17 GAX12082.1 - 3.8e-99 331.6 0.0 6.9e-99 330.8 0.0 1.3 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase Ank_5 PF13857.6 GAX12083.1 - 1.9e-13 50.4 0.0 7.6e-08 32.5 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX12083.1 - 3.3e-13 50.0 0.0 6.8e-10 39.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX12083.1 - 1.2e-11 44.9 1.1 6.9e-06 26.5 0.1 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX12083.1 - 3.4e-07 30.1 0.0 0.0039 17.6 0.0 4.4 5 1 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 GAX12083.1 - 1.3e-06 28.5 0.0 1 9.9 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat LRR_8 PF13855.6 GAX12086.1 - 2.1e-14 53.0 32.9 1.4e-05 24.8 5.8 4.2 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GAX12086.1 - 4.8e-11 42.7 32.4 0.0031 17.9 2.6 6.6 3 1 1 6 6 6 4 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 GAX12086.1 - 0.00074 19.6 11.1 0.0014 18.7 11.1 1.5 1 0 0 1 1 1 1 MYND finger DUF1772 PF08592.11 GAX12086.1 - 0.011 16.0 0.0 2.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) LRR_1 PF00560.33 GAX12086.1 - 0.93 10.3 21.6 57 4.9 0.0 7.6 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 GAX12087.1 - 9.5e-05 22.7 5.7 0.75 10.3 0.1 4.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX12087.1 - 0.51 10.1 4.5 0.7 9.7 0.6 3.0 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 GAX12087.1 - 1.9 9.3 4.4 86 4.3 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich Repeat GYF PF02213.16 GAX12088.1 - 6.1e-13 48.2 1.4 1.1e-12 47.3 1.4 1.5 1 0 0 1 1 1 1 GYF domain Wbp11 PF09429.10 GAX12088.1 - 2.1e-09 37.6 16.3 2.1e-09 37.6 16.3 3.5 2 1 1 3 3 3 1 WW domain binding protein 11 GYF_2 PF14237.6 GAX12088.1 - 4.4e-07 29.6 0.6 9.5e-07 28.5 0.6 1.5 1 0 0 1 1 1 1 GYF domain 2 NpwBP PF12622.7 GAX12088.1 - 0.012 16.3 22.6 0.012 16.3 22.6 4.5 2 2 0 2 2 2 0 mRNA biogenesis factor Trans_reg_C PF00486.28 GAX12088.1 - 6.4 6.9 8.0 20 5.3 0.1 3.6 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal Asp_Arg_Hydrox PF05118.15 GAX12089.1 - 1.6e-14 54.0 0.1 4.5e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_16 PF13432.6 GAX12089.1 - 2.9 8.6 7.3 1.8 9.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 GAX12090.1 - 2.4e-16 59.3 0.0 4.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX12090.1 - 2.6e-06 27.5 0.0 7.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif SLH PF00395.20 GAX12093.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 S-layer homology domain Linker_histone PF00538.19 GAX12095.1 - 1.2e-15 57.6 0.0 4.5e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 linker histone H1 and H5 family WSD PF15613.6 GAX12095.1 - 9.3e-09 35.7 0.0 1.1e-07 32.3 0.0 3.0 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PWWP PF00855.17 GAX12095.1 - 0.0024 18.3 0.0 0.0024 18.3 0.0 3.5 3 1 0 3 3 3 1 PWWP domain DUF413 PF04219.12 GAX12095.1 - 1.2 9.3 4.1 2.9 8.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF WD40 PF00400.32 GAX12096.1 - 0.00014 22.6 9.7 0.0066 17.3 0.8 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Utp8 PF10395.9 GAX12096.1 - 0.00035 19.2 0.0 0.00062 18.4 0.0 1.4 2 0 0 2 2 2 1 Utp8 family DPPIV_N PF00930.21 GAX12097.1 - 6.8e-62 209.3 0.0 6.2e-60 202.8 0.0 2.5 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAX12097.1 - 3.5e-55 186.8 0.0 5.3e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAX12097.1 - 6.4e-11 42.4 0.1 9.2e-09 35.3 0.1 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 GAX12097.1 - 4e-05 24.3 0.8 0.00016 22.4 0.8 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAX12097.1 - 6.3e-05 22.6 0.0 0.00017 21.2 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 GAX12097.1 - 0.0012 18.4 0.4 0.0021 17.6 0.4 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 GAX12097.1 - 0.0049 16.2 0.9 0.035 13.4 0.2 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PD40 PF07676.12 GAX12097.1 - 0.017 15.0 3.6 0.28 11.2 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat LIP PF03583.14 GAX12097.1 - 0.023 14.0 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_3 PF07859.13 GAX12097.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3141 PF11339.8 GAX12097.1 - 0.045 12.2 0.2 0.065 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Abhydrolase_1 PF00561.20 GAX12097.1 - 0.048 13.3 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 GAX12097.1 - 0.071 12.7 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2920 PF11144.8 GAX12097.1 - 0.25 10.5 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ribosom_S30AE_C PF16321.5 GAX12099.1 - 1.5e-21 75.8 0.1 3.1e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 GAX12099.1 - 2.6e-18 66.6 0.1 4.2e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein TnpB_IS66 PF05717.13 GAX12099.1 - 0.065 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 IS66 Orf2 like protein Pkinase PF00069.25 GAX12102.1 - 1.9e-36 125.8 0.0 1.2e-35 123.2 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12102.1 - 1.8e-34 119.2 0.0 5.2e-34 117.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX12102.1 - 0.024 13.9 0.0 0.17 11.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like SLBP_RNA_bind PF15247.6 GAX12102.1 - 0.13 12.3 0.4 0.3 11.2 0.4 1.6 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain tRNA-synt_1c PF00749.21 GAX12103.1 - 4.1e-102 341.3 0.0 5.4e-102 340.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAX12103.1 - 3.7e-42 144.1 0.0 1.9e-41 141.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_bind PF01588.20 GAX12103.1 - 3.1e-25 88.1 0.1 5.4e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain SNARE_assoc PF09335.11 GAX12104.1 - 2.6e-23 82.8 9.2 5.2e-23 81.8 9.2 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein zf-MYND PF01753.18 GAX12105.1 - 2.5e-08 33.9 36.8 1e-06 28.7 16.0 3.1 2 1 0 2 2 2 2 MYND finger zf-CCHC_5 PF14787.6 GAX12105.1 - 0.18 11.5 0.0 0.18 11.5 0.0 3.1 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger TPT PF03151.16 GAX12106.1 - 8.8e-24 84.3 13.0 1.2e-23 83.9 13.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX12106.1 - 8.2e-05 22.8 29.3 0.015 15.4 9.2 2.9 1 1 2 3 3 3 3 EamA-like transporter family DUF572 PF04502.13 GAX12107.1 - 4.1 6.9 18.9 6.6 6.3 18.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SBP PF03110.14 GAX12108.1 - 4 7.8 6.8 0.35 11.2 1.1 2.1 2 0 0 2 2 2 0 SBP domain PC-Esterase PF13839.6 GAX12109.1 - 5.1e-16 59.2 1.2 3.7e-09 36.8 0.9 2.4 1 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p zf-C3HC4_3 PF13920.6 GAX12110.1 - 1.9e-07 30.8 15.6 3.1e-07 30.1 15.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX12110.1 - 0.00012 21.9 13.6 0.00025 20.8 13.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAX12110.1 - 0.0021 17.9 15.4 0.0046 16.8 15.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX12110.1 - 0.0035 17.3 14.3 0.0076 16.2 14.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_MLP1_2 PF07926.12 GAX12110.1 - 0.0051 16.9 10.1 0.0051 16.9 10.1 7.3 5 1 2 7 7 7 3 TPR/MLP1/MLP2-like protein zf-RING_2 PF13639.6 GAX12110.1 - 0.0055 17.0 15.8 0.011 16.0 15.8 1.6 1 0 0 1 1 1 1 Ring finger domain CENP-H PF05837.12 GAX12110.1 - 0.02 15.3 0.5 0.02 15.3 0.5 8.0 4 2 4 8 8 8 0 Centromere protein H (CENP-H) PKcGMP_CC PF16808.5 GAX12110.1 - 0.053 13.4 0.2 0.053 13.4 0.2 7.6 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C3HC4 PF00097.25 GAX12110.1 - 0.054 13.4 17.4 0.11 12.4 17.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VBS PF08913.10 GAX12110.1 - 0.054 13.9 3.7 0.11 13.0 1.2 2.8 2 0 0 2 2 2 0 Vinculin Binding Site DUF1947 PF09183.10 GAX12110.1 - 0.38 11.1 3.0 0.61 10.4 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Zn_Tnp_IS1595 PF12760.7 GAX12111.1 - 0.0095 15.9 0.4 0.51 10.4 0.1 2.7 2 0 0 2 2 2 1 Transposase zinc-ribbon domain HypA PF01155.19 GAX12111.1 - 0.079 13.0 0.2 0.25 11.4 0.2 1.9 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin PF00301.20 GAX12111.1 - 0.11 12.6 4.6 1.9 8.5 4.6 2.3 1 1 0 1 1 1 0 Rubredoxin Titin_Ig-rpts PF06582.12 GAX12111.1 - 0.3 11.1 0.9 0.57 10.2 0.2 1.9 2 0 0 2 2 2 0 Titin repeat Lar_restr_allev PF14354.6 GAX12111.1 - 0.37 11.2 1.6 3.3 8.1 1.6 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar Rubredoxin_2 PF18073.1 GAX12111.1 - 0.51 10.1 3.6 12 5.8 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DNA_RNApol_7kD PF03604.13 GAX12111.1 - 1.6 8.4 4.4 11 5.8 4.4 2.1 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 GAX12111.1 - 3 8.1 4.8 14 5.9 4.9 2.1 1 1 1 2 2 2 0 Zinc ribbon domain COPI_assoc PF08507.10 GAX12112.1 - 8.3e-10 38.8 7.4 9.9e-10 38.6 7.4 1.1 1 0 0 1 1 1 1 COPI associated protein pKID PF02173.17 GAX12112.1 - 0.041 13.4 0.4 0.074 12.5 0.4 1.3 1 0 0 1 1 1 0 pKID domain DUF2232 PF09991.9 GAX12112.1 - 0.047 12.9 11.0 0.06 12.5 11.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) BTB PF00651.31 GAX12113.1 - 0.071 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain DNA_pol_B_N PF18094.1 GAX12113.1 - 0.076 13.6 0.2 0.23 12.0 0.2 1.9 1 1 0 1 1 1 0 DNA polymerase beta N-terminal domain U3_snoRNA_assoc PF08297.11 GAX12113.1 - 0.41 11.4 0.1 0.41 11.4 0.1 2.7 3 0 0 3 3 3 0 U3 snoRNA associated ArfGap PF01412.18 GAX12114.1 - 2.2e-32 111.6 0.0 2.9e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF4190 PF13828.6 GAX12114.1 - 0.052 13.3 0.9 0.084 12.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Pkinase PF00069.25 GAX12117.1 - 3.5e-60 203.6 0.0 6.6e-60 202.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12117.1 - 7.7e-39 133.5 0.0 1.5e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX12117.1 - 1.6e-05 24.4 0.0 3.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAX12117.1 - 0.11 12.4 0.3 0.85 9.5 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFMR PF07777.11 GAX12117.1 - 0.27 11.7 2.1 22 5.6 0.3 3.0 2 0 0 2 2 2 0 G-box binding protein MFMR ABC1 PF03109.16 GAX12119.1 - 4.7e-27 94.5 0.0 1.1e-26 93.3 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX12119.1 - 3.6e-06 27.1 0.0 1.2e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX12119.1 - 9.6e-05 21.9 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain DUF3825 PF12873.7 GAX12119.1 - 0.11 12.0 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3825) bZIP_2 PF07716.15 GAX12119.1 - 0.71 10.0 3.9 10 6.3 0.6 2.5 2 0 0 2 2 2 0 Basic region leucine zipper PhaP_Bmeg PF09602.10 GAX12119.1 - 1.2 9.0 3.9 9.1 6.2 0.2 3.0 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PRIMA1 PF16101.5 GAX12119.1 - 3.3 7.8 6.3 7 6.7 6.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MAPEG PF01124.18 GAX12120.1 - 8e-13 48.4 0.1 1.2e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 MAPEG family Nsp1_C PF05064.13 GAX12121.1 - 2.7e-14 52.9 4.2 2.7e-14 52.9 4.2 2.0 1 1 1 2 2 2 1 Nsp1-like C-terminal region ANT PF03374.14 GAX12121.1 - 0.12 12.7 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Streptin-Immun PF11083.8 GAX12121.1 - 0.19 12.1 5.4 12 6.4 0.3 3.1 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein YojJ PF10372.9 GAX12121.1 - 0.31 11.2 1.4 3.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Syntaxin-6_N PF09177.11 GAX12121.1 - 0.96 10.0 5.3 15 6.3 4.3 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 GAX12121.1 - 6.3 6.9 5.5 6.4 6.8 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 GAX12121.1 - 9.5 6.2 8.6 16 5.5 1.0 2.5 1 1 0 2 2 2 0 Laminin Domain II NAGPA PF09992.9 GAX12122.1 - 2.9e-14 53.6 0.1 6.3e-14 52.5 0.0 1.5 2 0 0 2 2 2 1 Phosphodiester glycosidase TFIIA PF03153.13 GAX12123.1 - 0.007 16.4 9.3 0.093 12.7 0.2 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Hist_deacetyl PF00850.19 GAX12124.1 - 7.2e-83 278.6 0.1 8.5e-83 278.3 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF1415 PF07209.12 GAX12125.1 - 8e-12 45.2 0.0 9.4e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) YqcI_YcgG PF08892.11 GAX12125.1 - 0.063 13.1 0.3 0.079 12.8 0.3 1.1 1 0 0 1 1 1 0 YqcI/YcgG family Myb_DNA-binding PF00249.31 GAX12127.1 - 1.2e-12 47.8 1.3 4.4e-07 30.0 0.7 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX12127.1 - 1.3e-05 25.4 3.7 0.0036 17.5 0.5 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX12127.1 - 0.2 11.6 13.5 0.049 13.5 0.5 3.4 3 0 0 3 3 3 0 Myb DNA-binding like Pkinase PF00069.25 GAX12128.1 - 1.2e-36 126.5 0.0 5.1e-36 124.4 0.0 2.0 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12128.1 - 1.9e-32 112.6 0.0 4.5e-32 111.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX12128.1 - 0.00024 20.0 0.0 0.00041 19.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Rhamno_transf PF11316.8 GAX12129.1 - 5.3e-13 48.9 0.0 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Putative rhamnosyl transferase X PF00739.19 GAX12129.1 - 0.095 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Trans-activation protein X mRNA_stabil PF13929.6 GAX12129.1 - 0.84 8.6 5.9 12 4.8 0.1 2.2 2 0 0 2 2 2 0 mRNA stabilisation SNF2_N PF00176.23 GAX12130.1 - 1.7e-63 214.5 0.1 3.7e-63 213.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX12130.1 - 1.4e-19 70.4 0.0 3.8e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX12130.1 - 4.1e-10 39.9 0.0 4.1e-10 39.9 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Chromo PF00385.24 GAX12130.1 - 3.7e-09 36.3 7.5 0.00022 21.1 0.2 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 GAX12130.1 - 1.1e-06 28.1 0.2 1.1e-06 28.1 0.2 2.6 4 0 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAX12130.1 - 0.0011 18.8 0.0 0.0031 17.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX12130.1 - 0.0091 16.3 0.0 0.072 13.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain BNIP2 PF12496.8 GAX12130.1 - 4.2 7.8 7.3 6.5 7.2 0.1 3.4 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Ank_2 PF12796.7 GAX12131.1 - 5.3e-20 71.8 0.0 1.6e-10 41.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX12131.1 - 4.1e-13 49.6 0.0 7.1e-06 26.5 0.0 4.5 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX12131.1 - 4.3e-08 32.8 0.0 8.7 7.3 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 GAX12131.1 - 1.2e-07 31.9 0.0 0.057 13.7 0.0 4.9 1 1 5 6 6 6 3 Ankyrin repeats (many copies) Flg_new PF09479.10 GAX12131.1 - 0.051 13.8 0.0 0.82 9.9 0.0 2.6 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Ank PF00023.30 GAX12131.1 - 0.066 13.7 0.0 46 4.7 0.0 4.0 5 0 0 5 5 5 0 Ankyrin repeat DUF1843 PF08898.10 GAX12131.1 - 0.086 13.4 0.7 6.9 7.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) ABC_tran PF00005.27 GAX12132.1 - 1.7e-32 112.8 0.0 4.4e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX12132.1 - 6.8e-29 101.4 5.3 8.5e-29 101.0 5.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAX12132.1 - 1.6e-06 27.7 0.1 2.1e-05 24.0 0.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX12132.1 - 0.00054 19.9 0.0 0.15 11.8 0.0 2.8 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX12132.1 - 0.00066 20.1 0.0 0.0016 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 GAX12132.1 - 0.005 16.6 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAX12132.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GAX12132.1 - 0.0072 16.1 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 GAX12132.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 GAX12132.1 - 0.019 15.3 0.1 0.063 13.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX12132.1 - 0.036 14.3 0.2 0.17 12.1 0.2 2.2 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 GAX12132.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 GAX12132.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 GAX12132.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 GAX12132.1 - 0.086 12.9 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Amidohydro_1 PF01979.20 GAX12132.1 - 0.15 11.3 0.5 0.63 9.3 0.1 1.9 1 1 1 2 2 2 0 Amidohydrolase family AAA_23 PF13476.6 GAX12132.1 - 0.17 12.3 2.1 0.25 11.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain adh_short PF00106.25 GAX12134.1 - 1.1e-23 83.8 0.0 3.7e-23 82.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX12134.1 - 1.1e-12 48.0 0.0 4.2e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX12134.1 - 2.6e-05 24.2 0.0 5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 KR domain MVP_shoulder PF11978.8 GAX12135.1 - 0.02 14.9 0.0 0.4 10.7 0.0 2.3 1 1 0 2 2 2 0 Shoulder domain bMG5 PF17972.1 GAX12135.1 - 0.038 14.4 1.6 1.4 9.3 0.1 3.0 1 1 3 4 4 4 0 Bacterial Alpha-2-macroglobulin MG5 domain FPRL1_inhibitor PF16104.5 GAX12135.1 - 0.066 13.4 2.0 0.33 11.1 0.1 2.4 2 0 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein DUF1104 PF06518.11 GAX12135.1 - 0.29 11.5 7.9 0.13 12.6 2.5 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1104) Exo_endo_phos PF03372.23 GAX12136.1 - 4.5e-06 26.3 0.1 7.9e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0506 PF11703.8 GAX12137.1 - 0.094 13.1 7.1 0.18 12.2 7.1 1.5 1 0 0 1 1 1 0 UPF0506 Trypan_PARP PF05887.11 GAX12137.1 - 2.8 7.9 16.0 3.3 7.7 12.1 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Trypsin PF00089.26 GAX12138.1 - 0.00021 21.2 0.3 0.00044 20.1 0.2 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX12138.1 - 0.0041 18.0 0.1 0.011 16.7 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin_2 PF13365.6 GAX12139.1 - 5.6e-18 66.3 0.1 1.3e-17 65.1 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX12139.1 - 1.1e-07 31.9 2.1 4e-07 30.1 2.1 1.9 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 GAX12139.1 - 0.063 11.9 2.0 3.4 6.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 NUMOD1 PF07453.13 GAX12139.1 - 0.12 12.7 0.0 0.63 10.4 0.0 2.1 2 0 0 2 2 2 0 NUMOD1 domain Peptidase_C4 PF00863.19 GAX12139.1 - 0.23 10.7 0.3 0.51 9.6 0.0 1.6 2 0 0 2 2 2 0 Peptidase family C4 4HBT PF03061.22 GAX12140.1 - 0.00084 19.6 0.1 1 9.7 0.0 3.2 3 0 0 3 3 3 2 Thioesterase superfamily tRNA_lig_CPD PF08302.11 GAX12141.1 - 0.0013 18.2 5.8 0.0038 16.7 1.5 2.9 2 1 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain HEM4 PF02602.15 GAX12141.1 - 0.013 14.9 0.2 0.14 11.5 0.1 2.4 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD DUF3861 PF12977.7 GAX12141.1 - 0.059 13.5 1.0 4 7.7 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) MutS_III PF05192.18 GAX12141.1 - 0.17 12.1 0.8 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 MutS domain III Trypsin_2 PF13365.6 GAX12142.1 - 4.5e-19 69.8 0.0 1.2e-18 68.4 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX12142.1 - 3.2e-09 36.9 0.6 9.9e-09 35.3 0.6 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 GAX12142.1 - 7.9e-05 21.5 0.7 0.011 14.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_C4 PF00863.19 GAX12142.1 - 0.094 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C4 Peptidase_S7 PF00949.21 GAX12142.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Trypsin_2 PF13365.6 GAX12143.1 - 9.7e-16 59.0 0.1 1.7e-15 58.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX12143.1 - 5e-06 26.5 0.3 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 GAX12143.1 - 0.011 14.4 1.1 2 6.9 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 Lipocalin_7 PF14651.6 GAX12143.1 - 0.026 14.4 0.1 0.27 11.2 0.0 2.4 2 1 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Peptidase_C4 PF00863.19 GAX12143.1 - 0.033 13.5 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C4 Peptidase_S39 PF02122.15 GAX12143.1 - 0.096 12.2 0.4 0.85 9.1 0.1 2.1 2 0 0 2 2 2 0 Peptidase S39 Trypsin_2 PF13365.6 GAX12144.1 - 2.8e-15 57.5 0.2 4.9e-15 56.7 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX12144.1 - 1.7e-05 24.7 8.0 8.4e-05 22.5 8.0 2.0 1 1 0 1 1 1 1 Trypsin Peptidase_S39 PF02122.15 GAX12144.1 - 0.07 12.6 1.1 1.1 8.7 0.2 2.2 2 0 0 2 2 2 0 Peptidase S39 Peptidase_S46 PF10459.9 GAX12144.1 - 0.11 11.1 3.8 1.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 Peptidase_C4 PF00863.19 GAX12144.1 - 0.15 11.4 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C4 Toxin_27 PF08099.11 GAX12144.1 - 0.7 10.0 9.2 1.3 9.2 9.2 1.4 1 0 0 1 1 1 0 Scorpion calcine family TonB_N PF16031.5 GAX12144.1 - 4 8.0 29.2 6.8 7.2 29.2 1.2 1 0 0 1 1 1 0 TonB polyproline region CaMKII_AD PF08332.10 GAX12145.1 - 4.7e-39 133.5 0.0 2e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 GAX12145.1 - 2.6e-38 131.0 0.0 2.2e-13 50.5 0.0 3.3 3 0 0 3 3 3 3 SnoaL-like domain DUF4440 PF14534.6 GAX12145.1 - 4.4e-29 101.0 0.1 1.6e-08 34.9 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 GAX12145.1 - 5.1e-18 65.6 0.1 3.1e-05 24.6 0.0 3.3 3 0 0 3 3 3 3 SnoaL-like domain DUF3225 PF11533.8 GAX12145.1 - 3.6e-14 52.6 0.1 1.7e-05 24.6 0.0 3.8 3 2 0 3 3 3 3 Protein of unknown function (DUF3225) SnoaL_4 PF13577.6 GAX12145.1 - 6.3e-14 52.2 1.6 0.00014 22.0 0.0 4.7 3 2 0 3 3 3 3 SnoaL-like domain NTF2 PF02136.20 GAX12145.1 - 0.061 13.9 0.0 26 5.4 0.0 3.4 4 0 0 4 4 4 0 Nuclear transport factor 2 (NTF2) domain Skp1 PF01466.19 GAX12145.1 - 0.16 12.1 2.9 27 5.0 0.0 4.3 5 0 0 5 5 5 0 Skp1 family, dimerisation domain CaMKII_AD PF08332.10 GAX12146.1 - 3.2e-75 250.4 0.1 6.6e-19 68.3 0.0 4.1 4 0 0 4 4 4 4 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 GAX12146.1 - 1.5e-48 163.6 0.3 1.1e-11 45.1 0.0 4.2 4 0 0 4 4 4 4 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 GAX12146.1 - 5.2e-45 152.6 0.1 9.6e-10 38.8 0.0 4.8 4 2 0 4 4 4 4 SnoaL-like domain SnoaL_2 PF12680.7 GAX12146.1 - 4.9e-29 101.0 0.0 2.5e-07 31.3 0.0 4.2 4 0 0 4 4 4 4 SnoaL-like domain SnoaL_4 PF13577.6 GAX12146.1 - 1.3e-17 64.2 11.6 0.00024 21.2 0.1 6.9 5 3 0 5 5 5 4 SnoaL-like domain DUF3225 PF11533.8 GAX12146.1 - 5.8e-07 29.3 0.3 2.2 8.0 0.0 4.9 4 2 0 4 4 4 2 Protein of unknown function (DUF3225) DUF959 PF06121.14 GAX12146.1 - 4e-05 24.0 0.9 8 6.7 0.0 4.1 4 0 0 4 4 4 1 Domain of Unknown Function (DUF959) MecA_N PF05223.11 GAX12146.1 - 0.0013 19.0 1.1 61 3.9 0.0 4.8 5 0 0 5 5 5 0 NTF2-like N-terminal transpeptidase domain DUF3692 PF12469.8 GAX12146.1 - 0.0014 18.9 0.0 47 4.2 0.0 4.2 4 0 0 4 4 4 0 CRISPR-associated protein Herpes_gE PF02480.16 GAX12146.1 - 0.002 16.9 0.0 4.1 6.1 0.0 3.8 2 1 0 4 4 4 1 Alphaherpesvirus glycoprotein E Endopep_inhib PF16800.5 GAX12146.1 - 0.0059 16.5 2.3 22 5.0 0.1 4.1 4 0 0 4 4 4 0 IseA DL-endopeptidase inhibitor Skp1 PF01466.19 GAX12146.1 - 0.011 15.9 0.0 18 5.5 0.0 4.2 4 0 0 4 4 4 0 Skp1 family, dimerisation domain DUF4101 PF13355.6 GAX12146.1 - 0.016 15.7 5.1 24 5.4 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4101) FB_lectin PF07367.11 GAX12146.1 - 0.02 14.9 0.1 31 4.5 0.0 3.5 3 0 0 3 3 3 0 Fungal fruit body lectin NTF2 PF02136.20 GAX12146.1 - 0.047 14.3 0.0 36 5.0 0.0 3.9 4 0 0 4 4 4 0 Nuclear transport factor 2 (NTF2) domain Inhibitor_G39P PF11417.8 GAX12146.1 - 0.048 14.2 0.6 24 5.6 0.1 4.2 5 0 0 5 5 4 0 Loader and inhibitor of phage G40P EpoR_lig-bind PF09067.10 GAX12146.1 - 0.072 13.3 0.0 1.6e+02 2.5 0.0 3.9 4 0 0 4 4 4 0 Erythropoietin receptor, ligand binding PSD3 PF07626.11 GAX12146.1 - 0.15 12.5 0.1 36 4.9 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1587) PilJ_C PF18223.1 GAX12146.1 - 0.22 12.0 7.8 40 4.8 0.2 4.3 4 0 0 4 4 4 0 Pili PilJ C-terminal domain Dynactin_p62 PF05502.13 GAX12147.1 - 0.009 14.8 0.1 0.009 14.8 0.1 3.1 2 1 0 3 3 3 1 Dynactin p62 family Transthyretin PF00576.21 GAX12147.1 - 0.093 13.4 0.0 1.2 9.9 0.0 2.3 2 0 0 2 2 2 0 HIUase/Transthyretin family cobW PF02492.19 GAX12148.1 - 3.8e-49 166.7 0.4 6.1e-49 166.0 0.4 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX12148.1 - 7.3e-19 67.5 0.0 6.3e-18 64.5 0.0 2.2 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAX12148.1 - 0.00019 21.4 0.1 0.2 11.6 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 GAX12148.1 - 0.0016 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 GAX12148.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAX12148.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 GAX12148.1 - 0.053 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 GAX12148.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 GAX12148.1 - 0.12 12.9 0.0 0.44 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 GAX12148.1 - 0.2 10.6 0.3 1.4 7.8 0.0 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CaMKII_AD PF08332.10 GAX12149.1 - 8.2e-59 197.3 0.0 5e-19 68.7 0.0 3.1 3 0 0 3 3 3 3 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 GAX12149.1 - 1.5e-38 131.4 0.0 1.9e-12 47.6 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 GAX12149.1 - 1.2e-33 116.0 0.0 1.1e-09 38.5 0.0 3.6 3 1 0 3 3 3 3 SnoaL-like domain SnoaL_2 PF12680.7 GAX12149.1 - 2.6e-25 89.0 0.0 3.3e-08 34.1 0.0 3.2 3 0 0 3 3 3 3 SnoaL-like domain SnoaL_4 PF13577.6 GAX12149.1 - 2.7e-12 46.9 8.4 0.0012 19.0 0.3 5.3 4 2 0 4 4 4 3 SnoaL-like domain DUF3225 PF11533.8 GAX12149.1 - 1.3e-05 24.9 0.4 2.1 8.0 0.0 3.9 4 1 0 4 4 4 2 Protein of unknown function (DUF3225) DUF959 PF06121.14 GAX12149.1 - 0.00014 22.1 0.6 9.4 6.4 0.0 3.2 3 0 0 3 3 3 1 Domain of Unknown Function (DUF959) Herpes_gE PF02480.16 GAX12149.1 - 0.013 14.3 0.0 13 4.4 0.0 3.0 1 1 0 3 3 3 0 Alphaherpesvirus glycoprotein E NTF2 PF02136.20 GAX12149.1 - 0.018 15.6 0.0 7.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Nuclear transport factor 2 (NTF2) domain Mvb12 PF09452.10 GAX12149.1 - 0.02 15.3 0.0 24 5.5 0.0 3.3 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 MecA_N PF05223.11 GAX12149.1 - 0.021 15.1 1.7 13 6.1 0.0 3.9 5 0 0 5 5 4 0 NTF2-like N-terminal transpeptidase domain Anth_synt_I_N PF04715.13 GAX12149.1 - 0.031 14.5 0.0 36 4.6 0.0 3.3 3 0 0 3 3 3 0 Anthranilate synthase component I, N terminal region DUF3692 PF12469.8 GAX12149.1 - 0.052 13.8 0.0 30 4.9 0.0 3.2 2 1 1 3 3 3 0 CRISPR-associated protein PilJ_C PF18223.1 GAX12149.1 - 0.059 13.9 2.4 26 5.4 0.0 3.4 3 0 0 3 3 3 0 Pili PilJ C-terminal domain DUF4101 PF13355.6 GAX12149.1 - 0.12 12.8 1.3 67 4.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4101) Endopep_inhib PF16800.5 GAX12149.1 - 0.12 12.3 0.4 28 4.6 0.0 2.9 3 0 0 3 3 3 0 IseA DL-endopeptidase inhibitor SinI PF08671.10 GAX12149.1 - 0.56 10.1 1.6 1.5 8.7 0.1 2.6 3 0 0 3 3 3 0 Anti-repressor SinI Lon_C PF05362.13 GAX12150.1 - 2.4e-73 246.1 0.0 6e-73 244.7 0.0 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 GAX12150.1 - 1.5e-24 87.0 0.2 6.9e-24 84.9 0.0 2.2 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GAX12150.1 - 6.9e-17 62.1 0.0 4e-16 59.6 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 GAX12150.1 - 5.8e-08 32.6 0.0 1.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 GAX12150.1 - 6.2e-06 26.3 0.7 0.0007 19.6 0.0 3.5 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX12150.1 - 6.9e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 GAX12150.1 - 7.5e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain TIP49 PF06068.13 GAX12150.1 - 0.00056 19.2 0.1 0.0013 18.0 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 GAX12150.1 - 0.00085 19.6 1.7 0.22 11.8 0.1 3.5 3 1 1 4 4 3 1 AAA domain AAA_16 PF13191.6 GAX12150.1 - 0.0017 18.8 0.6 0.0064 16.9 0.0 2.4 3 0 0 3 3 1 1 AAA ATPase domain AAA_2 PF07724.14 GAX12150.1 - 0.0025 18.0 0.0 0.1 12.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 GAX12150.1 - 0.0065 16.2 1.0 0.039 13.7 0.1 2.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAX12150.1 - 0.0067 17.0 0.4 0.018 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 GAX12150.1 - 0.01 15.4 0.5 0.16 11.5 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAX12150.1 - 0.016 14.6 0.2 0.18 11.1 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Phage_connect_1 PF05135.13 GAX12150.1 - 0.023 15.2 0.3 0.076 13.5 0.3 2.0 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein AAA_19 PF13245.6 GAX12150.1 - 0.039 14.3 0.6 0.13 12.6 0.2 2.1 2 0 0 2 2 1 0 AAA domain MCM PF00493.23 GAX12150.1 - 0.053 12.6 0.1 0.21 10.6 0.0 1.9 1 1 1 2 2 2 0 MCM P-loop domain NTPase_1 PF03266.15 GAX12150.1 - 0.071 13.0 0.2 1.8 8.4 0.0 3.1 2 1 1 3 3 3 0 NTPase IstB_IS21 PF01695.17 GAX12150.1 - 0.074 12.8 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Exonuc_VII_L PF02601.15 GAX12150.1 - 0.079 12.5 0.3 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3235 PF11574.8 GAX12150.1 - 0.089 13.7 0.0 0.23 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) TsaE PF02367.17 GAX12150.1 - 0.092 12.7 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 GAX12150.1 - 0.16 11.8 0.0 0.49 10.3 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase AAA_11 PF13086.6 GAX12150.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 GAX12150.1 - 0.3 11.2 2.1 0.43 10.7 0.0 2.3 3 0 0 3 3 2 0 Shikimate kinase Fib_alpha PF08702.10 GAX12150.1 - 3 8.0 5.2 7 6.8 5.2 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SRR1 PF07985.12 GAX12151.1 - 1.3e-11 44.3 0.0 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 SRR1 ALAD PF00490.21 GAX12153.1 - 3.5e-141 469.9 0.0 4.2e-141 469.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase BatA PF07584.11 GAX12154.1 - 0.0017 18.7 2.6 0.0026 18.1 0.4 2.2 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal ZapB PF06005.12 GAX12154.1 - 0.093 13.2 1.2 0.093 13.2 1.2 2.4 3 0 0 3 3 3 0 Cell division protein ZapB Voltage_CLC PF00654.20 GAX12154.1 - 0.21 10.8 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel DUF1772 PF08592.11 GAX12154.1 - 0.23 11.8 0.1 0.23 11.8 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Glycos_transf_4 PF00953.21 GAX12155.1 - 1.1e-35 123.0 12.4 1.1e-35 123.0 12.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 4 YfhO PF09586.10 GAX12155.1 - 0.0062 14.9 0.7 0.012 13.9 0.7 1.4 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Pkinase PF00069.25 GAX12156.1 - 4.9e-41 140.8 0.0 6.4e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12156.1 - 1.2e-21 77.1 0.0 4.6e-21 75.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX12156.1 - 5.4e-05 23.2 0.4 0.00022 21.2 0.4 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX12156.1 - 0.037 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GAX12156.1 - 0.039 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 GAX12156.1 - 0.045 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 GAX12156.1 - 0.3 10.0 0.1 0.44 9.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain BolA PF01722.18 GAX12158.1 - 1.6e-13 50.7 0.0 2.5e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein Mg_chelatase PF01078.21 GAX12159.1 - 2.8e-13 49.7 0.6 1.2e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 GAX12159.1 - 8e-13 49.0 0.1 3e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_lid_2 PF17863.1 GAX12159.1 - 6.3e-12 45.2 1.9 6.5e-12 45.1 0.2 2.0 2 0 0 2 2 1 1 AAA lid domain VWA PF00092.28 GAX12159.1 - 1.1e-07 32.3 0.0 2.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activat PF00158.26 GAX12159.1 - 1.7e-06 27.8 0.0 0.0068 16.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain MCM PF00493.23 GAX12159.1 - 2.4e-06 26.8 0.0 5.9e-05 22.3 0.0 2.5 2 1 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 GAX12159.1 - 0.00037 20.5 0.1 0.072 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mito_fiss_reg PF05308.11 GAX12159.1 - 0.00062 19.9 3.9 0.00097 19.3 3.9 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator Sigma54_activ_2 PF14532.6 GAX12159.1 - 0.0039 17.3 0.1 1.8 8.7 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 GAX12159.1 - 0.0072 16.7 0.2 0.16 12.3 0.2 2.8 1 1 0 1 1 1 1 AAA ATPase domain VIR_N PF15912.5 GAX12159.1 - 0.021 14.4 4.3 0.044 13.4 4.3 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal VWA_CoxE PF05762.14 GAX12159.1 - 0.025 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CAP_N PF01213.19 GAX12159.1 - 0.034 13.6 5.8 0.054 13.0 5.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_7 PF12775.7 GAX12159.1 - 0.058 12.9 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_Ag35 PF03286.14 GAX12159.1 - 0.085 12.6 4.9 0.2 11.4 4.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.13 GAX12159.1 - 0.21 11.4 6.1 0.97 9.3 4.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region PAXIP1_C PF15364.6 GAX12159.1 - 2.2 8.6 15.3 6.9 7.0 15.3 1.8 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein FAM176 PF14851.6 GAX12159.1 - 6.5 6.4 7.5 4.4 7.0 5.4 1.7 2 0 0 2 2 2 0 FAM176 family PTPS PF01242.19 GAX12160.1 - 5.4e-20 71.6 0.0 6.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase TPT PF03151.16 GAX12161.1 - 9.8e-66 222.0 16.5 1.1e-65 221.9 16.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX12161.1 - 3.4e-09 37.0 19.1 1.3e-07 31.9 2.4 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAX12161.1 - 0.0043 16.3 12.4 0.0061 15.8 9.2 2.1 1 1 1 2 2 2 1 UAA transporter family PUNUT PF16913.5 GAX12161.1 - 0.17 11.0 16.1 0.37 10.0 16.2 1.5 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Chloroa_b-bind PF00504.21 GAX12162.1 - 4.9e-34 118.2 0.1 6.6e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CLAMP PF14769.6 GAX12163.1 - 0.075 13.5 0.3 0.94 10.0 0.0 2.5 2 1 1 3 3 3 0 Flagellar C1a complex subunit C1a-32 COPI_assoc PF08507.10 GAX12164.1 - 3.8e-05 23.8 12.4 0.00029 20.9 12.4 1.9 1 1 0 1 1 1 1 COPI associated protein HlyIII PF03006.20 GAX12164.1 - 0.014 15.2 3.0 0.019 14.7 3.0 1.3 1 0 0 1 1 1 0 Haemolysin-III related DUF3995 PF13160.6 GAX12164.1 - 0.15 12.5 3.5 1.5 9.2 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) bZIP_1 PF00170.21 GAX12165.1 - 1.5e-09 37.8 10.6 2.8e-09 36.9 10.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX12165.1 - 1.6e-07 31.3 9.9 3e-07 30.4 9.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper MCC-bdg_PDZ PF10506.9 GAX12165.1 - 0.035 14.1 1.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_Maf PF03131.17 GAX12165.1 - 0.045 14.3 5.6 0.098 13.2 5.6 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor VWA_2 PF13519.6 GAX12166.1 - 3.3e-08 34.1 0.1 4.7e-07 30.4 0.0 2.7 4 0 0 4 4 4 1 von Willebrand factor type A domain VWA PF00092.28 GAX12166.1 - 2.7e-05 24.5 0.1 0.00024 21.4 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Het-C PF07217.11 GAX12166.1 - 0.00018 20.2 0.0 0.0003 19.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF5536 PF17688.1 GAX12166.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5536) Hydrolase_4 PF12146.8 GAX12167.1 - 1.3e-13 50.8 0.0 1.9e-08 33.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX12167.1 - 1.3e-09 38.1 0.3 1.9e-07 31.0 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX12167.1 - 1.2e-07 31.4 0.0 4.8e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAX12167.1 - 8.7e-07 29.8 0.2 0.0003 21.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF818 PF05677.12 GAX12167.1 - 1.9e-06 27.1 0.0 2.4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 GAX12167.1 - 0.00024 21.0 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAX12167.1 - 0.0035 17.2 0.0 0.026 14.3 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1749 PF08538.10 GAX12167.1 - 0.0069 15.5 0.0 0.01 14.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) DLH PF01738.18 GAX12167.1 - 0.013 15.1 0.0 0.063 12.8 0.0 2.0 1 1 1 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.13 GAX12167.1 - 0.078 12.6 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 GAX12167.1 - 0.17 11.2 0.1 1.5 8.0 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Proteasome PF00227.26 GAX12168.1 - 5.2e-43 146.8 0.0 5.9e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SNF2_N PF00176.23 GAX12169.1 - 3.1e-70 236.6 0.2 3.1e-70 236.6 0.2 3.9 4 0 0 4 4 4 1 SNF2 family N-terminal domain Bromodomain PF00439.25 GAX12169.1 - 1e-19 70.4 0.0 3.9e-19 68.5 0.0 2.1 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 GAX12169.1 - 2.6e-18 66.4 0.0 2.6e-18 66.4 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.6 GAX12169.1 - 0.0016 19.0 0.0 0.0016 19.0 0.0 4.3 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Vps4_C PF09336.10 GAX12169.1 - 0.058 13.4 0.1 0.32 11.0 0.1 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AhpC-TSA_2 PF13911.6 GAX12170.1 - 1.4e-12 47.7 0.0 2.7e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme RRM_3 PF08777.11 GAX12171.1 - 1.6e-13 50.5 9.7 2.2e-12 46.9 1.8 2.9 2 1 0 2 2 2 2 RNA binding motif La PF05383.17 GAX12171.1 - 1.5e-10 40.9 0.2 3.3e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GAX12171.1 - 1.8e-07 30.9 0.1 1.6e-06 27.8 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSN1_7TM PF02714.15 GAX12172.1 - 2.1e-09 37.1 8.6 1.6e-08 34.2 8.6 2.3 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Anoctamin PF04547.12 GAX12172.1 - 0.00016 20.7 2.8 0.00016 20.7 2.8 2.1 1 1 1 2 2 2 1 Calcium-activated chloride channel Rsm22 PF09243.10 GAX12173.1 - 2.5e-30 105.7 0.1 6.2e-21 74.9 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 MRP-S31 PF15433.6 GAX12173.1 - 0.0075 16.0 2.6 0.014 15.0 2.6 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Phage_Mu_Gam PF07352.12 GAX12173.1 - 0.0083 16.0 1.3 0.015 15.2 1.3 1.4 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein RIG-I_C PF18119.1 GAX12173.1 - 0.013 15.5 0.1 0.04 13.9 0.1 1.8 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain Methyltransf_24 PF13578.6 GAX12173.1 - 0.014 16.4 0.0 0.048 14.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX12173.1 - 0.014 16.1 0.1 0.06 14.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAX12173.1 - 0.024 15.3 0.0 0.11 13.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MipZ PF09140.11 GAX12173.1 - 0.028 13.7 0.2 0.16 11.2 0.0 2.0 1 1 1 2 2 2 0 ATPase MipZ DNA_pol_phi PF04931.13 GAX12173.1 - 0.59 8.2 9.1 1.2 7.2 9.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 GAX12173.1 - 9.4 6.7 15.2 2.5 8.5 9.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Urb2 PF10441.9 GAX12174.1 - 5.8e-17 62.3 12.2 1e-16 61.5 3.1 3.7 3 0 0 3 3 3 2 Urb2/Npa2 family NDK PF00334.19 GAX12175.1 - 3.2e-05 23.9 0.0 0.0077 16.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase FtsH_ext PF06480.15 GAX12175.1 - 0.053 13.9 0.1 0.31 11.4 0.1 2.2 1 1 0 1 1 1 0 FtsH Extracellular TPP_enzyme_N PF02776.18 GAX12176.1 - 2.2e-39 134.8 0.0 5.6e-39 133.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAX12176.1 - 1.4e-34 119.1 0.0 3e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAX12176.1 - 1.2e-33 115.7 0.0 2.2e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain RRM_1 PF00076.22 GAX12177.1 - 6.1e-15 54.8 0.1 3e-10 39.7 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lyase_1 PF00206.20 GAX12178.1 - 6.2e-21 75.1 0.0 8.6e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 GAX12178.1 - 2.6e-19 69.5 0.1 1.2e-18 67.4 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HMG_box PF00505.19 GAX12179.1 - 2.2e-18 66.4 0.3 5e-18 65.3 0.3 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX12179.1 - 1.5e-17 63.9 0.0 5.1e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain FTCD_C PF04961.12 GAX12179.1 - 0.12 12.1 0.4 0.19 11.5 0.4 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Med31 PF05669.12 GAX12180.1 - 1.7e-28 98.4 1.6 2e-28 98.2 1.6 1.1 1 0 0 1 1 1 1 SOH1 M16C_assoc PF08367.11 GAX12181.1 - 7e-61 205.5 0.5 1e-60 205.0 0.5 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GAX12181.1 - 4.9e-25 88.6 0.0 1.1e-21 77.7 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAX12181.1 - 1.9e-07 31.1 0.3 1e-06 28.8 0.0 2.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF4423 PF14394.6 GAX12181.1 - 0.44 10.2 2.2 0.46 10.2 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) HEAT PF02985.22 GAX12183.1 - 8.4e-29 97.2 38.3 0.0001 22.2 0.1 13.7 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 GAX12183.1 - 6.2e-20 71.4 29.9 2e-05 24.9 1.6 7.7 1 1 6 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 GAX12183.1 - 5.3e-14 52.4 13.1 0.0036 17.8 0.1 8.0 6 1 1 7 7 7 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAX12183.1 - 1.7e-12 47.7 1.7 0.012 16.2 0.0 6.0 4 2 2 6 6 6 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAX12183.1 - 6.2e-08 32.8 8.5 0.03 14.4 0.0 5.2 3 3 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 GAX12183.1 - 0.0072 15.9 1.2 2 7.9 0.0 3.9 4 1 0 4 4 4 1 CLASP N terminal Adaptin_N PF01602.20 GAX12183.1 - 0.013 14.1 2.9 0.033 12.8 1.5 2.6 2 2 0 2 2 2 0 Adaptin N terminal region CitMHS PF03600.16 GAX12183.1 - 0.036 13.3 0.4 6.5 5.9 0.3 2.6 2 1 0 2 2 2 0 Citrate transporter Arm PF00514.23 GAX12183.1 - 0.094 12.8 0.5 1.3e+02 2.8 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 GAX12183.1 - 0.47 9.5 4.8 4.5 6.3 0.1 4.0 2 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Caudo_TAP PF02413.17 GAX12184.1 - 0.32 11.1 2.9 0.87 9.7 0.5 2.4 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Cadherin_4 PF17803.1 GAX12184.1 - 8.7 7.1 7.7 1.4 9.6 3.1 2.0 2 0 0 2 2 2 0 Bacterial cadherin-like domain cobW PF02492.19 GAX12185.1 - 1.2e-45 155.2 0.8 1.8e-45 154.7 0.8 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX12185.1 - 9.4e-20 70.3 0.0 3.1e-19 68.7 0.0 1.9 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAX12185.1 - 0.0043 17.0 1.2 0.62 9.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MobB PF03205.14 GAX12185.1 - 0.011 15.6 0.8 0.64 9.9 0.3 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 GAX12185.1 - 0.014 15.9 0.7 0.04 14.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAX12185.1 - 0.03 14.3 0.1 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 GAX12185.1 - 0.033 13.1 0.1 0.06 12.3 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 GAX12185.1 - 0.036 14.3 0.1 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX12185.1 - 0.037 14.4 0.3 0.079 13.3 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 GAX12185.1 - 0.055 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF853 PF05872.12 GAX12185.1 - 0.065 11.8 0.5 0.13 10.9 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA PF00004.29 GAX12185.1 - 0.07 13.6 0.1 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 GAX12185.1 - 0.086 12.0 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 GAX12185.1 - 0.097 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 GAX12185.1 - 0.13 11.5 4.1 0.18 11.0 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.25 GAX12186.1 - 1.4e-44 152.5 0.0 1.4e-28 100.0 0.1 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12186.1 - 3.4e-30 105.2 0.0 1.4e-21 76.9 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 GAX12186.1 - 0.0043 16.4 0.0 0.053 12.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Viral_P18 PF04521.13 GAX12186.1 - 0.1 12.4 0.2 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein APH PF01636.23 GAX12186.1 - 0.12 12.3 0.8 2.2 8.1 1.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family UB2H PF14814.6 GAX12186.1 - 0.15 12.1 0.3 0.33 11.0 0.3 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain Tachylectin PF14517.6 GAX12188.1 - 0.18 11.3 0.4 21 4.6 0.0 2.8 2 1 0 2 2 2 0 Tachylectin 2OG-FeII_Oxy_3 PF13640.6 GAX12189.1 - 3.3e-13 50.3 0.0 1.1e-12 48.7 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BTB PF00651.31 GAX12190.1 - 2e-05 24.7 0.0 6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Chon_Sulph_att PF06566.11 GAX12190.1 - 3.5 7.4 8.8 1.4 8.7 2.4 2.4 2 0 0 2 2 2 0 Chondroitin sulphate attachment domain ThiF PF00899.21 GAX12191.1 - 1.6e-07 31.0 0.0 0.006 16.0 0.0 2.2 2 0 0 2 2 2 2 ThiF family LETM1 PF07766.13 GAX12191.1 - 0.11 11.8 0.0 5.6 6.2 0.0 2.1 2 0 0 2 2 2 0 LETM1-like protein Ribosomal_L7Ae PF01248.26 GAX12194.1 - 6.1e-17 61.1 0.0 6.7e-17 61.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 GAX12194.1 - 0.00021 21.1 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 PELOTA RNA binding domain Pico_P2B PF01552.17 GAX12194.1 - 0.03 14.5 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Picornavirus 2B protein RNase_P_pop3 PF08228.11 GAX12194.1 - 0.071 13.2 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 SLBP_RNA_bind PF15247.6 GAX12195.1 - 1.8e-24 85.6 2.7 5.1e-24 84.2 2.7 1.8 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain bZIP_1 PF00170.21 GAX12195.1 - 0.025 14.6 1.8 0.046 13.8 1.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor fn3_PAP PF17808.1 GAX12195.1 - 0.036 14.2 0.2 0.054 13.6 0.2 1.3 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Ion_trans_2 PF07885.16 GAX12196.1 - 5.8e-24 83.9 22.3 1.3e-15 57.1 12.2 3.3 3 0 0 3 3 3 3 Ion channel EF-hand_6 PF13405.6 GAX12196.1 - 1.9e-07 30.5 0.1 0.0069 16.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAX12196.1 - 3.4e-06 26.2 1.5 0.031 13.8 0.1 2.8 2 1 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAX12196.1 - 3.5e-06 27.4 0.1 0.13 12.8 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX12196.1 - 2.8e-05 23.4 3.1 0.023 14.2 0.2 2.9 2 1 0 2 2 2 2 EF hand Ion_trans PF00520.31 GAX12196.1 - 0.00075 18.8 7.7 0.00075 18.8 7.7 1.9 2 0 0 2 2 2 1 Ion transport protein EF-hand_8 PF13833.6 GAX12196.1 - 0.0038 17.0 2.1 0.69 9.8 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 GAX12196.1 - 0.27 11.4 0.6 1.5 9.1 0.5 2.0 1 1 1 2 2 2 0 Dockerin type I domain DIOX_N PF14226.6 GAX12197.1 - 1.2e-27 97.1 0.0 1.4e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TLD PF07534.16 GAX12198.1 - 2.5e-20 73.1 0.0 5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 TLD Med10 PF09748.9 GAX12198.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Nicastrin PF05450.15 GAX12199.1 - 4.3e-21 75.4 0.3 1.2e-20 74.0 0.3 1.7 1 1 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 GAX12199.1 - 2.9e-13 50.2 0.0 6.7e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 GAX12199.1 - 4.4e-07 29.8 0.1 1.9e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.25 GAX12200.1 - 4.1e-48 164.1 0.0 1.6e-32 113.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12200.1 - 1e-29 103.6 0.0 3.4e-23 82.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.6 GAX12200.1 - 5.2e-07 29.5 0.5 8.8e-06 25.5 0.2 2.6 2 1 1 3 3 3 2 PQQ-like domain Kinase-like PF14531.6 GAX12200.1 - 0.00042 19.7 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PQQ PF01011.21 GAX12200.1 - 0.01 15.7 0.3 8.4 6.5 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat DUF1971 PF09313.11 GAX12200.1 - 0.039 14.0 0.1 0.097 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Kdo PF06293.14 GAX12200.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.21 GAX12201.1 - 2.2e-24 86.5 0.0 4.2e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DJ-1_PfpI PF01965.24 GAX12202.1 - 2.8e-40 137.8 0.0 3.2e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family UPF0160 PF03690.13 GAX12203.1 - 1.4e-113 379.7 0.0 1.6e-113 379.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rad17 PF03215.15 GAX12204.1 - 4.8e-20 72.3 0.0 8.9e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 GAX12204.1 - 0.00011 22.3 0.0 0.00039 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAX12204.1 - 0.00023 21.1 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAX12204.1 - 0.00077 19.7 0.0 0.002 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX12204.1 - 0.00078 19.9 0.6 0.0068 16.8 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 GAX12204.1 - 0.0028 18.1 0.0 0.012 16.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAX12204.1 - 0.0091 15.4 0.0 0.96 8.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein ABC_tran PF00005.27 GAX12204.1 - 0.016 15.8 0.1 0.054 14.0 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 GAX12204.1 - 0.019 15.2 0.0 0.17 12.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAX12204.1 - 0.022 14.6 0.1 0.075 12.9 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 GAX12204.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TP2 PF01254.18 GAX12204.1 - 0.042 14.5 1.2 0.089 13.4 1.2 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 MMR_HSR1 PF01926.23 GAX12204.1 - 0.066 13.3 0.0 0.19 11.9 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 GAX12204.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAX12204.1 - 0.087 12.1 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 GAX12204.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_assoc_2 PF16193.5 GAX12204.1 - 0.15 12.4 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain DNA_pol3_delta PF06144.13 GAX12204.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit T2SSE PF00437.20 GAX12204.1 - 0.17 10.9 0.1 1.8 7.5 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein TPR_1 PF00515.28 GAX12205.1 - 6.3e-09 35.3 9.2 0.00019 21.1 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX12205.1 - 1.1e-08 34.5 19.0 0.0017 18.3 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX12205.1 - 2.4e-06 27.1 5.6 0.0018 17.9 0.7 3.1 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 GAX12205.1 - 3.7e-06 26.6 0.2 0.011 15.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX12205.1 - 5.9e-06 26.5 11.5 0.05 13.9 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX12205.1 - 9.4e-06 25.5 17.3 0.0016 18.5 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX12205.1 - 0.00011 22.6 5.4 1.4 9.7 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX12205.1 - 0.0011 19.5 9.2 1 10.3 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX12205.1 - 0.0019 18.0 7.9 0.48 10.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX12205.1 - 0.0073 16.9 6.2 0.24 12.1 0.3 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 GAX12205.1 - 0.0084 16.2 4.8 4.9 7.2 2.7 3.4 2 1 1 3 3 3 2 Domain of Unknown Function (DUF3856) p450 PF00067.22 GAX12206.1 - 1e-76 258.6 0.0 1.2e-76 258.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAX12207.1 - 3.6e-12 45.9 21.7 3.6e-12 45.9 21.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX12207.1 - 9.5e-06 24.7 13.7 2.3e-05 23.5 13.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltr_RsmB-F PF01189.17 GAX12208.1 - 6.5e-67 225.1 0.0 1.1e-66 224.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 GAX12208.1 - 3e-08 34.0 0.0 7.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 GAX12208.1 - 0.0021 18.2 0.1 0.0036 17.4 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 GAX12208.1 - 0.0026 17.5 0.0 0.0067 16.2 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAX12208.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mg_chelatase_C PF13335.6 GAX12208.1 - 0.045 14.4 0.1 0.14 12.8 0.1 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Copine PF07002.16 GAX12209.1 - 1.7e-35 122.5 0.0 2.8e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX12209.1 - 1.7e-08 34.7 0.0 6e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX12209.1 - 0.035 14.2 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 vWA found in TerF C terminus Copine PF07002.16 GAX12210.1 - 1.8e-50 171.4 0.1 2.4e-50 171.0 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX12210.1 - 1.2e-19 70.4 0.0 2.5e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX12210.1 - 5.3e-06 26.7 0.0 1.3e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 vWA found in TerF C terminus WD40 PF00400.32 GAX12211.1 - 1.3e-34 117.7 31.2 4.6e-07 30.4 0.0 11.6 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.12 GAX12211.1 - 1.3e-16 60.9 0.7 2.4e-16 60.0 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 GAX12211.1 - 0.068 11.8 0.9 6.3 5.3 0.0 3.2 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Hira PF07569.11 GAX12211.1 - 0.17 11.6 0.1 4 7.1 0.2 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF4196 PF13846.6 GAX12212.1 - 0.041 14.1 1.1 0.041 14.1 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) PTPA PF03095.15 GAX12214.1 - 7.8e-92 307.9 0.0 9.4e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein GCV_T PF01571.21 GAX12215.1 - 1.2e-65 221.5 0.0 1.8e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 GAX12215.1 - 1.1e-59 202.8 0.4 1.5e-59 202.4 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 GAX12215.1 - 1.9e-13 50.5 0.2 7.2e-13 48.7 0.2 2.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 GAX12215.1 - 6.6e-09 35.4 0.0 8.5e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX12215.1 - 1.1e-05 24.8 0.8 2e-05 23.9 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain SoxG PF04268.12 GAX12215.1 - 2.5e-05 24.5 0.0 5.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family NAD_binding_8 PF13450.6 GAX12215.1 - 6.9e-05 23.0 0.5 0.00017 21.7 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAX12215.1 - 0.00057 20.4 0.4 0.016 15.7 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX12215.1 - 0.0009 18.4 0.4 0.013 14.6 0.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAX12215.1 - 0.0014 17.9 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAX12215.1 - 0.0028 16.9 0.1 0.0086 15.4 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX12215.1 - 0.003 16.5 1.1 0.29 9.9 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 GAX12215.1 - 0.0046 16.9 0.3 0.39 10.7 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding ApbA PF02558.16 GAX12215.1 - 0.013 15.2 0.1 0.036 13.7 0.1 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 GAX12215.1 - 0.024 13.9 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 GAX12215.1 - 0.027 14.7 0.2 2.2 8.6 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain DUF3291 PF11695.8 GAX12215.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) AlaDh_PNT_C PF01262.21 GAX12215.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.23 GAX12215.1 - 0.12 12.4 0.5 26 4.9 0.0 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Peripla_BP_3 PF13377.6 GAX12215.1 - 0.16 12.3 0.1 0.77 10.1 0.0 2.3 2 0 0 2 2 1 0 Periplasmic binding protein-like domain Shikimate_DH PF01488.20 GAX12215.1 - 0.17 11.9 0.3 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DNA_topoisoIV PF00521.20 GAX12218.1 - 4.3e-108 361.9 0.0 6.1e-108 361.5 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAX12218.1 - 2.5e-38 131.3 0.1 4.5e-38 130.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAX12218.1 - 1.5e-14 53.9 0.0 2.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GAX12218.1 - 6.7e-10 39.5 0.0 1.5e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAX12218.1 - 7e-06 26.2 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Glyco_hydro_42C PF08533.10 GAX12218.1 - 0.056 13.2 0.0 3 7.6 0.0 2.6 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain FTCD PF02971.14 GAX12219.1 - 0.0079 16.2 0.1 0.0097 16.0 0.1 1.2 1 0 0 1 1 1 1 Formiminotransferase domain Gly-zipper_OmpA PF13436.6 GAX12220.1 - 3.3e-11 42.8 21.0 3.3e-11 42.8 21.0 1.9 2 0 0 2 2 2 1 Glycine-zipper domain SAM_1 PF00536.30 GAX12220.1 - 1.3e-08 35.2 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Gly-zipper_YMGG PF13441.6 GAX12220.1 - 2.1e-08 33.8 23.1 2.1e-08 33.8 23.1 2.0 2 0 0 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 GAX12220.1 - 7.4e-06 25.9 21.2 7.4e-06 25.9 21.2 2.0 2 0 0 2 2 2 1 Glycine zipper SAM_2 PF07647.17 GAX12220.1 - 2.2e-05 24.5 0.0 3.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1269 PF06897.12 GAX12220.1 - 0.0075 16.5 7.3 0.014 15.7 7.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) Romo1 PF10247.9 GAX12220.1 - 0.038 14.3 5.1 1.4 9.3 1.3 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DEC-1_N PF04625.13 GAX12220.1 - 0.22 10.5 3.2 0.28 10.2 3.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region EII-Sor PF03609.14 GAX12220.1 - 0.3 10.5 2.9 0.41 10.0 2.9 1.1 1 0 0 1 1 1 0 PTS system sorbose-specific iic component DUF3482 PF11981.8 GAX12220.1 - 2.7 7.3 8.2 4.8 6.5 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Mu-like_Pro PF10123.9 GAX12222.1 - 0.088 12.3 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein GhoS PF11080.8 GAX12223.1 - 0.014 15.4 0.6 0.044 13.8 0.0 2.2 2 0 0 2 2 2 0 Endoribonuclease GhoS GFO_IDH_MocA PF01408.22 GAX12224.1 - 0.00043 21.1 0.0 0.00084 20.2 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DEAD PF00270.29 GAX12225.1 - 1.9e-38 132.0 0.2 4.4e-38 130.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12225.1 - 1.1e-19 70.8 0.0 3.5e-19 69.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX12225.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Lipoprotein_18 PF06804.11 GAX12225.1 - 0.014 14.4 0.2 0.029 13.4 0.2 1.5 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Toxin_15 PF07906.13 GAX12226.1 - 0.0016 18.1 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 ShET2 enterotoxin, N-terminal region Asp_Arg_Hydrox PF05118.15 GAX12227.1 - 3.2e-27 95.3 0.0 5.9e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Pkinase PF00069.25 GAX12229.1 - 3.7e-38 131.4 0.0 5.3e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12229.1 - 1.8e-18 66.8 0.0 1.3e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX12229.1 - 3e-07 30.6 0.0 6.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX12229.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 GAX12229.1 - 0.03 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX12229.1 - 0.056 12.8 0.0 0.73 9.1 0.0 2.3 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GAX12229.1 - 0.082 11.7 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 GAX12229.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.22 GAX12229.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SOUL PF04832.12 GAX12230.1 - 4.9e-44 150.5 0.4 1.1e-43 149.3 0.4 1.6 1 0 0 1 1 1 1 SOUL heme-binding protein DUF4806 PF16064.5 GAX12230.1 - 0.052 13.9 0.3 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) Bap31_Bap29_C PF18035.1 GAX12230.1 - 0.053 13.5 0.7 0.053 13.5 0.7 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain RuvX PF03652.15 GAX12231.1 - 1.6e-22 80.3 1.0 1.3e-21 77.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction resolvase Trypsin_2 PF13365.6 GAX12232.1 - 0.079 13.9 0.0 0.17 12.7 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain adh_short PF00106.25 GAX12233.1 - 9.6e-27 93.7 0.2 1.1e-19 70.6 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX12233.1 - 3.7e-16 59.4 0.0 3.5e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX12233.1 - 2.1e-08 34.3 0.2 3.2e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAX12233.1 - 0.057 12.8 0.0 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX12233.1 - 0.07 12.6 0.5 0.088 12.3 0.5 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATP-synt_ab PF00006.25 GAX12233.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF4079 PF13301.6 GAX12234.1 - 2.9e-21 76.1 7.6 2.9e-21 76.1 7.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) DUF3185 PF11381.8 GAX12234.1 - 0.027 14.5 1.3 0.093 12.8 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) EMP70 PF02990.16 GAX12235.1 - 1.4e-156 522.3 6.9 1.4e-156 522.3 6.9 1.7 2 0 0 2 2 2 1 Endomembrane protein 70 DUF4079 PF13301.6 GAX12235.1 - 6.3e-18 65.3 9.7 6.3e-18 65.3 9.7 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4079) Tocopherol_cycl PF14249.6 GAX12236.1 - 2.8e-122 408.1 3.7 3.4e-122 407.8 3.7 1.0 1 0 0 1 1 1 1 Tocopherol cyclase DUF2939 PF11159.8 GAX12237.1 - 0.064 13.7 0.2 2.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) MFS_1 PF07690.16 GAX12238.1 - 7.1e-28 97.5 20.4 9.8e-28 97.1 20.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Elong_Iki1 PF10483.9 GAX12239.1 - 5.6e-06 26.1 0.0 7.5e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 ELP6 PF09807.9 GAX12239.1 - 3.6e-05 23.3 0.0 9.5e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Elongation complex protein 6 HAD_SAK_2 PF18143.1 GAX12239.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Mito_fiss_Elm1 PF06258.11 GAX12239.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission ELM1 IF4E PF01652.18 GAX12240.1 - 9.9e-49 165.2 2.2 1.2e-48 164.9 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CBM77 PF18283.1 GAX12240.1 - 0.056 13.8 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding module 77 Peptidase_M48 PF01435.18 GAX12241.1 - 5.9e-34 117.6 0.1 1e-33 116.8 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M48 RuvA_N PF01330.21 GAX12241.1 - 0.17 12.0 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 RuvA N terminal domain CHU_C PF13585.6 GAX12242.1 - 0.1 12.6 1.1 0.26 11.4 0.6 1.8 1 1 1 2 2 2 0 C-terminal domain of CHU protein family PhoD_N PF16655.5 GAX12242.1 - 0.14 12.7 1.0 0.29 11.7 0.5 1.9 1 1 1 2 2 2 0 PhoD-like phosphatase, N-terminal domain Beach PF02138.18 GAX12243.1 - 7e-103 343.8 0.0 9.9e-103 343.3 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAX12243.1 - 6.2e-10 39.1 0.0 7.3e-05 22.8 0.0 3.6 2 1 1 3 3 3 3 PH domain associated with Beige/BEACH WD40 PF00400.32 GAX12243.1 - 2.3e-05 25.1 9.3 0.049 14.5 0.6 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat GRAM PF02893.20 GAX12243.1 - 0.0076 16.1 0.0 1.3 8.9 0.0 2.8 3 0 0 3 3 3 1 GRAM domain Methyltransf_4 PF02390.17 GAX12245.1 - 1.7e-24 86.2 0.0 4.3e-23 81.7 0.0 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAX12245.1 - 0.093 13.5 0.1 0.54 11.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF1445 PF07286.12 GAX12246.1 - 2.7e-57 192.7 0.0 3.9e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) NRD1_2 PF01995.16 GAX12246.1 - 8e-06 25.3 0.0 0.0032 16.8 0.0 2.8 2 1 0 2 2 2 2 NrpR regulatory domains NRD1 and 2 CHASE PF03924.13 GAX12247.1 - 1.7e-22 80.3 0.0 3.1e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.26 GAX12247.1 - 5.3e-20 72.0 0.1 1.7e-19 70.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAX12247.1 - 0.00042 20.3 0.1 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HisKA PF00512.25 GAX12247.1 - 0.0042 17.1 0.3 0.023 14.7 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF3365 PF11845.8 GAX12247.1 - 0.13 12.5 0.6 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) LapA_dom PF06305.11 GAX12247.1 - 0.19 11.6 0.8 6.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CHASE PF03924.13 GAX12248.1 - 9.3e-22 77.9 0.1 1.5e-21 77.2 0.1 1.3 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.26 GAX12248.1 - 3.7e-21 75.7 0.0 8.4e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX12248.1 - 6.9e-12 45.5 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX12248.1 - 5.7e-05 23.1 0.3 0.00018 21.5 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 GAX12248.1 - 0.0032 17.4 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Tom37 PF10568.9 GAX12248.1 - 0.057 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein HATPase_c PF02518.26 GAX12249.1 - 1.6e-19 70.5 0.0 3.3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE PF03924.13 GAX12249.1 - 3.5e-17 63.0 0.1 5.9e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 CHASE domain Response_reg PF00072.24 GAX12249.1 - 1.4e-13 51.0 0.0 2.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 GAX12249.1 - 0.0088 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA PF00512.25 GAX12249.1 - 0.011 15.8 0.1 0.037 14.1 0.0 2.0 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Tetraspanin PF00335.20 GAX12249.1 - 0.092 12.4 0.1 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Tetraspanin family Imm17 PF15562.6 GAX12249.1 - 0.1 12.4 0.1 0.31 11.0 0.1 1.8 1 0 0 1 1 1 0 Immunity protein 17 CHASE PF03924.13 GAX12250.1 - 5.9e-24 85.0 0.2 1e-23 84.2 0.2 1.4 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.26 GAX12250.1 - 2.7e-21 76.2 0.0 8.1e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX12250.1 - 2.5e-13 50.2 0.0 5.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX12250.1 - 0.00066 19.7 1.9 0.00078 19.4 0.2 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 GAX12250.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Es2 PF09751.9 GAX12251.1 - 1.4e-25 90.9 15.8 1.9e-17 64.2 9.7 2.3 2 0 0 2 2 2 2 Nuclear protein Es2 FAM220 PF15487.6 GAX12251.1 - 0.3 10.7 5.7 0.056 13.1 1.6 1.8 2 0 0 2 2 2 0 FAM220 family MAD PF05557.13 GAX12252.1 - 5.5e-17 61.4 75.1 2.5e-13 49.3 75.2 3.6 1 1 0 1 1 1 1 Mitotic checkpoint protein BST2 PF16716.5 GAX12252.1 - 0.0062 17.1 5.3 0.0062 17.1 5.3 6.9 5 1 1 6 6 6 2 Bone marrow stromal antigen 2 GCP_C_terminal PF04130.13 GAX12253.1 - 6.3e-55 186.8 9.2 1.2e-54 185.9 9.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAX12253.1 - 4.7e-44 151.2 0.0 1.2e-43 149.9 0.0 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal zf-C2H2_10 PF16588.5 GAX12254.1 - 0.013 15.3 0.1 0.013 15.3 0.1 1.6 2 0 0 2 2 2 0 C2H2 zinc-finger DUF1231 PF06802.11 GAX12254.1 - 0.041 13.0 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) zf-CCHC PF00098.23 GAX12254.1 - 0.041 14.0 0.9 0.069 13.3 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GAX12254.1 - 0.092 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Glyco_transf_64 PF09258.10 GAX12255.1 - 4e-46 157.3 0.0 5.3e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain HTH_1 PF00126.27 GAX12257.1 - 0.054 13.4 0.2 0.19 11.7 0.2 1.9 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family tRNA_U5-meth_tr PF05958.11 GAX12257.1 - 0.067 12.2 0.0 14 4.5 0.0 3.0 2 2 2 4 4 4 0 tRNA (Uracil-5-)-methyltransferase Peptidase_S51 PF03575.17 GAX12258.1 - 1.1e-22 80.8 0.0 4.1e-22 78.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S51 HAD_2 PF13419.6 GAX12259.1 - 5.2e-07 29.9 0.0 0.00017 21.7 0.0 2.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase zinc_ribbon_2 PF13240.6 GAX12259.1 - 0.00022 20.8 3.7 0.00022 20.8 3.7 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Hydrolase PF00702.26 GAX12259.1 - 0.00046 20.5 0.1 0.0018 18.6 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DZR PF12773.7 GAX12259.1 - 0.005 16.8 0.8 0.005 16.8 0.8 1.8 2 0 0 2 2 2 1 Double zinc ribbon Hydrolase_like PF13242.6 GAX12259.1 - 0.0079 16.2 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like zinc_ribbon_15 PF17032.5 GAX12259.1 - 0.028 15.2 0.1 0.066 14.0 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family D5_N PF08706.11 GAX12259.1 - 0.11 12.8 0.1 0.33 11.2 0.1 1.8 2 0 0 2 2 2 0 D5 N terminal like Hydrolase_6 PF13344.6 GAX12259.1 - 0.15 12.2 0.0 1.1 9.4 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-ribbon_3 PF13248.6 GAX12259.1 - 0.21 11.0 1.5 0.43 10.0 1.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Glyco_trans_1_4 PF13692.6 GAX12260.1 - 5.4e-10 39.8 0.0 1.1e-08 35.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX12260.1 - 2.4e-08 33.7 0.0 1.4e-07 31.2 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAX12260.1 - 5.3e-06 27.0 0.1 1e-05 26.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GAX12260.1 - 4.4e-05 23.5 0.0 8.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 GAX12260.1 - 0.012 16.0 0.0 0.042 14.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 HIT PF01230.23 GAX12261.1 - 1.7e-22 80.0 0.0 3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAX12261.1 - 1.3e-15 57.9 0.0 2e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GST_C_2 PF13410.6 GAX12261.1 - 2.7e-09 36.9 0.0 8e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX12261.1 - 0.0003 20.9 0.0 0.00066 19.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX12261.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAX12261.1 - 0.0081 16.7 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX12261.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAX12261.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.29 GAX12262.1 - 2.9e-43 147.7 0.3 4.1e-43 147.2 0.3 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12262.1 - 2.3e-29 102.0 2.0 3.5e-28 98.2 0.6 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX12262.1 - 4.6e-06 26.7 0.0 7.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX12262.1 - 0.00037 19.8 0.1 0.00055 19.2 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 GAX12262.1 - 0.033 14.5 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 GAX12262.1 - 0.089 12.1 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 GAX12262.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NmrA PF05368.13 GAX12263.1 - 1.4e-14 54.3 0.0 1.2e-13 51.1 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAX12263.1 - 3.6e-14 53.1 0.0 1.4e-13 51.1 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 GAX12263.1 - 0.002 17.6 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAX12263.1 - 0.0029 17.6 0.1 0.049 13.5 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAX12263.1 - 0.003 17.1 0.1 0.013 15.0 0.1 2.1 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAX12263.1 - 0.073 13.3 0.1 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 GAX12263.1 - 0.1 12.0 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX12263.1 - 0.19 10.8 0.1 0.52 9.4 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ribosomal_L9_C PF03948.14 GAX12264.1 - 4.8e-15 55.8 0.4 9.1e-15 54.9 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Tau95 PF09734.9 GAX12264.1 - 0.043 14.6 0.0 0.093 13.5 0.0 1.4 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF3783 PF12646.7 GAX12265.1 - 0.0031 17.4 7.4 1 9.4 0.1 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF3783) Skp1 PF01466.19 GAX12265.1 - 0.014 15.5 15.8 7.6 6.7 0.1 6.5 4 2 3 7 7 7 0 Skp1 family, dimerisation domain Ribosomal_S13_N PF08069.12 GAX12265.1 - 0.017 15.1 0.2 0.13 12.3 0.0 2.7 2 1 1 3 3 3 0 Ribosomal S13/S15 N-terminal domain PocR PF10114.9 GAX12265.1 - 0.99 9.2 3.5 2.7 7.8 0.3 2.9 1 1 0 2 2 2 0 Sensory domain found in PocR PRP38 PF03371.15 GAX12266.1 - 5.7e-44 150.0 0.0 8.3e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 PRP38 family WD40 PF00400.32 GAX12267.1 - 3.1e-40 135.4 17.5 1e-09 38.8 0.2 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX12267.1 - 5.7e-17 61.8 0.3 0.00042 20.5 0.0 5.6 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 GAX12267.1 - 9.5e-09 34.9 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 GAX12267.1 - 2.4e-07 30.8 1.2 0.33 10.8 0.0 4.5 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Trypan_PARP PF05887.11 GAX12267.1 - 0.0013 18.7 3.7 0.0034 17.4 3.7 1.7 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Nbas_N PF15492.6 GAX12267.1 - 0.017 14.5 0.1 0.14 11.5 0.0 2.5 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 GAX12267.1 - 0.022 14.1 0.0 5 6.3 0.0 3.0 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2574 PF10836.8 GAX12267.1 - 0.067 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) WD40_like PF17005.5 GAX12267.1 - 0.11 11.8 0.0 17 4.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain RL10P_insert PF17777.1 GAX12268.1 - 1.8e-21 75.9 0.0 2.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GAX12268.1 - 6.9e-08 32.6 0.1 1.1e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ndufs5 PF10200.9 GAX12269.1 - 1.7e-05 24.9 0.4 1.9e-05 24.8 0.4 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 GAX12269.1 - 0.0059 16.8 0.4 0.0059 16.8 0.4 1.9 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb Ribosomal_L28 PF00830.19 GAX12270.1 - 4.9e-17 61.9 3.4 6e-17 61.6 3.4 1.1 1 0 0 1 1 1 1 Ribosomal L28 family Phage_lysozyme2 PF18013.1 GAX12270.1 - 0.044 13.8 0.1 0.055 13.5 0.1 1.0 1 0 0 1 1 1 0 Phage tail lysozyme Ribonuc_red_lgC PF02867.15 GAX12271.1 - 7.2e-184 612.2 0.0 8.7e-184 611.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAX12271.1 - 9e-20 70.5 0.0 3.5e-19 68.6 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAX12271.1 - 0.00056 20.4 0.0 0.0016 19.0 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain ubiquitin PF00240.23 GAX12272.1 - 6.3e-34 115.6 0.9 1.2e-33 114.7 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 GAX12272.1 - 3.4e-19 68.7 1.8 3.4e-19 68.7 1.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GAX12272.1 - 4e-16 58.6 3.4 5.3e-16 58.2 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX12272.1 - 1.3e-05 25.6 0.3 7.8e-05 23.1 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX12272.1 - 0.00068 19.7 0.3 0.0016 18.5 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 GAX12272.1 - 0.0036 17.2 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAX12272.1 - 0.012 15.9 0.1 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 GAX12272.1 - 0.015 15.9 0.5 0.021 15.4 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX12272.1 - 0.069 13.2 0.7 9 6.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Lipase_GDSL_2 PF13472.6 GAX12273.1 - 0.0088 16.5 0.0 3.9 7.8 0.0 2.6 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family SpoIISA_toxin PF14171.6 GAX12273.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Chloroa_b-bind PF00504.21 GAX12274.1 - 9.5e-32 110.8 0.0 1.2e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Aquarius_N PF16399.5 GAX12275.1 - 0.023 12.8 2.7 0.88 7.5 0.0 2.9 2 1 1 3 3 3 0 Intron-binding protein aquarius N-terminus DUF1847 PF08901.11 GAX12275.1 - 0.028 14.1 0.3 0.053 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) MRNIP PF15749.5 GAX12275.1 - 1.1 10.0 14.9 0.2 12.4 9.6 2.4 3 0 0 3 3 3 0 MRN-interacting protein Borrelia_P83 PF05262.11 GAX12275.1 - 1.4 7.3 10.7 2.1 6.7 10.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.8 GAX12275.1 - 1.9 7.3 11.0 3.6 6.4 11.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.9 GAX12275.1 - 3.5 7.2 23.2 0.88 9.1 18.0 2.1 2 0 0 2 2 2 0 DDRGK domain Vma12 PF11712.8 GAX12275.1 - 4.5 7.3 7.1 3.1 7.9 0.1 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase POX PF07526.11 GAX12275.1 - 5.2 7.6 8.3 40 4.8 4.0 2.4 2 0 0 2 2 2 0 Associated with HOX Ham1p_like PF01725.16 GAX12276.1 - 3.1e-54 183.8 0.0 3.6e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF4827 PF16109.5 GAX12276.1 - 0.18 11.8 0.1 0.29 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) TFIIE-A_C PF11521.8 GAX12277.1 - 7.8 6.9 14.1 7.9 6.9 1.1 3.4 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Aldo_ket_red PF00248.21 GAX12278.1 - 1.1e-20 74.0 0.0 5e-19 68.6 0.0 2.8 1 1 0 1 1 1 1 Aldo/keto reductase family Apc13p PF05839.11 GAX12279.1 - 0.0099 16.1 0.9 0.028 14.6 0.9 1.8 1 1 0 1 1 1 1 Apc13p protein Spermine_synth PF01564.17 GAX12280.1 - 6.6e-15 55.0 0.1 2e-14 53.4 0.1 1.9 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 GAX12280.1 - 8.1e-12 45.3 0.8 6.4e-09 36.0 0.2 3.0 3 0 0 3 3 3 2 S-adenosylmethionine decarboxylase SET PF00856.28 GAX12280.1 - 4.2e-09 37.0 0.0 2.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 SET domain DUF3352 PF11832.8 GAX12280.1 - 0.098 11.3 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) TPR_1 PF00515.28 GAX12281.1 - 9.5e-20 69.5 4.5 2.5e-05 23.9 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX12281.1 - 2.4e-16 58.5 11.3 0.00019 21.3 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX12281.1 - 7.7e-16 56.9 3.8 7.4e-05 22.7 0.2 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX12281.1 - 1.2e-12 47.5 10.2 0.0001 22.8 0.0 6.5 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX12281.1 - 1.8e-12 47.6 1.8 0.00072 20.0 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX12281.1 - 5.3e-12 46.2 5.7 3.9e-06 27.4 0.1 5.2 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX12281.1 - 1.1e-09 37.6 6.9 0.0018 18.2 0.0 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX12281.1 - 6e-09 36.0 1.9 0.00049 20.3 0.1 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAX12281.1 - 1.4e-08 34.3 0.1 3.2e-05 23.5 0.0 4.0 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 GAX12281.1 - 1e-07 32.1 7.1 0.0033 17.7 0.2 6.2 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX12281.1 - 1.6e-07 31.3 3.3 1.2e-05 25.3 0.1 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX12281.1 - 9.4e-06 25.7 1.4 1.3 9.6 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX12281.1 - 2.1e-05 24.9 4.2 0.27 11.9 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAX12281.1 - 0.023 15.0 1.4 0.13 12.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX12281.1 - 0.049 13.7 1.4 1.1 9.4 0.1 3.0 2 1 1 3 3 2 0 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 GAX12281.1 - 0.057 13.1 0.7 2.9 7.6 0.1 3.3 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 GAX12281.1 - 0.087 12.8 0.1 0.33 11.0 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat CCDC-167 PF15188.6 GAX12281.1 - 0.1 13.0 0.2 1.1 9.6 0.0 2.8 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 TPR_10 PF13374.6 GAX12281.1 - 0.16 11.8 4.6 2 8.4 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 GAX12282.1 - 8.9e-61 201.8 0.8 4.6e-22 77.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1471 PF07338.13 GAX12282.1 - 0.032 14.2 0.1 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) Serine_protease PF18405.1 GAX12282.1 - 0.041 13.0 0.1 0.16 11.1 0.1 2.0 2 0 0 2 2 2 0 Gammaproteobacterial serine protease IMS PF00817.20 GAX12283.1 - 5.1e-39 133.7 0.0 5.1e-39 133.7 0.0 2.2 3 0 0 3 3 3 1 impB/mucB/samB family BRCT_2 PF16589.5 GAX12283.1 - 7.9e-10 39.0 0.0 2.3e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAX12283.1 - 1.1e-07 32.2 0.0 2.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAX12283.1 - 3e-07 30.3 0.0 6.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 GAX12283.1 - 1.4e-05 25.3 0.0 4.2e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 GAX12283.1 - 0.00022 21.4 0.0 0.00089 19.5 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.8 GAX12283.1 - 0.00064 20.4 0.0 0.21 12.3 0.0 3.1 2 1 1 3 3 3 2 impB/mucB/samB family C-terminal domain PPI_Ypi1 PF07491.11 GAX12283.1 - 0.05 13.4 0.1 0.22 11.4 0.1 2.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor FMN_dh PF01070.18 GAX12283.1 - 0.06 12.4 0.4 0.2 10.7 0.1 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Metallophos PF00149.28 GAX12284.1 - 1.3e-05 25.8 0.7 1.3e-05 25.8 0.7 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase B PF02216.16 GAX12284.1 - 0.069 13.1 0.1 0.35 10.9 0.1 2.0 2 0 0 2 2 2 0 B domain Monooxygenase_B PF04744.12 GAX12284.1 - 0.19 10.5 0.0 3.3 6.4 0.0 2.0 2 0 0 2 2 2 0 Monooxygenase subunit B protein CTP_transf_like PF01467.26 GAX12285.1 - 1.1e-16 61.3 0.0 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Herpes_U15 PF05613.11 GAX12285.1 - 0.061 14.0 0.1 0.16 12.7 0.1 1.7 1 0 0 1 1 1 0 Human herpesvirus U15 protein CDP-OH_P_transf PF01066.21 GAX12285.1 - 0.11 13.3 0.4 0.11 13.3 0.4 2.8 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase ATXN-1_C PF12547.8 GAX12285.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator Ribosomal_S16 PF00886.19 GAX12286.1 - 1e-24 86.3 0.0 1.5e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 LRR_6 PF13516.6 GAX12287.1 - 9e-05 22.2 5.7 0.083 13.0 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 GAX12287.1 - 0.0021 18.5 0.7 0.23 11.9 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX12287.1 - 0.1 12.3 0.5 3.9 7.3 0.3 3.4 3 1 0 3 3 3 0 Leucine rich repeat Rhamno_transf PF11316.8 GAX12288.1 - 8.6e-12 44.9 0.7 1.2e-05 24.8 0.2 2.2 2 0 0 2 2 2 2 Putative rhamnosyl transferase Spexin PF15171.6 GAX12289.1 - 0.007 16.6 3.0 2.9 8.2 0.1 2.8 3 0 0 3 3 3 2 Neuropeptide secretory protein family, NPQ, spexin TPR_1 PF00515.28 GAX12289.1 - 0.11 12.3 9.0 1.2 9.1 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX12289.1 - 0.26 11.5 10.1 10 6.5 1.7 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Adaptin_binding PF10199.9 GAX12289.1 - 0.36 11.4 4.1 1.1 9.9 4.1 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 TPR_6 PF13174.6 GAX12289.1 - 2.6 8.9 4.3 6.8 7.6 1.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 GAX12290.1 - 2.3e-44 149.2 3.2 5.7e-19 67.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S41 PF03572.18 GAX12291.1 - 1.4e-35 122.3 0.0 5.8e-35 120.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GAX12291.1 - 1.1e-08 34.8 0.2 2.9e-08 33.4 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX12291.1 - 9.2e-05 22.7 0.1 0.0003 21.1 0.1 1.9 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX12291.1 - 0.0001 22.5 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SET PF00856.28 GAX12292.1 - 5.7e-05 23.6 0.0 0.00017 22.0 0.0 1.8 1 1 0 1 1 1 1 SET domain PhyH PF05721.13 GAX12293.1 - 5.9e-16 59.4 0.0 1.2e-15 58.3 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) YebG PF07130.12 GAX12294.1 - 0.016 15.0 1.8 0.36 10.7 0.0 2.6 2 0 0 2 2 2 0 YebG protein TPR_1 PF00515.28 GAX12295.1 - 1.6e-08 34.0 11.1 0.023 14.5 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX12295.1 - 2e-06 28.0 17.8 0.036 14.3 1.7 5.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX12295.1 - 6.8e-06 25.8 9.9 4.3 7.7 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX12295.1 - 0.00023 20.8 3.5 4 7.2 0.0 4.0 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 GAX12295.1 - 0.00065 19.7 8.8 4.8 7.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAX12295.1 - 0.042 13.6 6.8 2.1 8.0 0.4 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain AATF-Che1 PF13339.6 GAX12295.1 - 0.043 14.5 0.3 0.043 14.5 0.3 3.3 3 1 1 4 4 4 0 Apoptosis antagonizing transcription factor SNAP PF14938.6 GAX12295.1 - 0.045 13.2 5.7 1.3 8.4 5.1 2.6 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 GAX12295.1 - 0.066 13.9 0.3 0.066 13.9 0.3 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat Acetyltransf_18 PF18014.1 GAX12295.1 - 0.085 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF695 PF05117.12 GAX12295.1 - 0.12 12.6 1.5 0.23 11.6 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF695) DSPc PF00782.20 GAX12295.1 - 0.13 12.1 0.3 3.3 7.5 0.1 2.6 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain TPR_7 PF13176.6 GAX12295.1 - 0.18 11.9 16.7 9.1 6.6 0.0 6.4 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX12295.1 - 0.2 12.6 22.1 3.9 8.5 0.8 6.6 3 2 4 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 GAX12295.1 - 0.77 9.9 11.6 1.3 9.1 0.3 5.4 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 GAX12295.1 - 2.4 8.7 20.2 7.1 7.2 0.8 4.9 3 1 0 4 4 4 0 Tetratricopeptide repeat Fes1 PF08609.10 GAX12296.1 - 2e-05 25.4 1.0 0.0047 17.8 0.1 2.5 2 0 0 2 2 2 2 Nucleotide exchange factor Fes1 Rcd1 PF04078.13 GAX12296.1 - 0.00064 19.1 0.2 0.0031 16.8 0.0 2.1 1 1 1 2 2 2 1 Cell differentiation family, Rcd1-like RasGAP_C PF03836.15 GAX12296.1 - 0.07 13.3 1.0 0.17 12.0 1.0 1.6 1 0 0 1 1 1 0 RasGAP C-terminus Ribosomal_S24e PF01282.19 GAX12297.1 - 3.9e-32 110.0 0.0 7.2e-32 109.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Histone PF00125.24 GAX12298.1 - 1.3e-18 67.6 0.0 1.8e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 GAX12298.1 - 4.8e-13 48.6 0.9 9.3e-13 47.7 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 GAX12298.1 - 0.00039 20.6 0.0 0.00053 20.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAX12299.1 - 1.1e-13 51.5 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 GAX12299.1 - 0.039 14.0 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Ribosomal_S2 PF00318.20 GAX12300.1 - 2.5e-26 92.3 0.1 4.6e-14 52.2 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 2OG-FeII_Oxy_2 PF13532.6 GAX12301.1 - 8.4e-13 48.9 0.0 1.1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX12301.1 - 0.01 16.3 0.2 0.036 14.5 0.1 1.9 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PhoD PF09423.10 GAX12302.1 - 2.1e-13 50.1 0.0 3.6e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase CPL PF08144.11 GAX12303.1 - 1e-08 35.6 3.0 9.6e-07 29.2 0.1 3.7 2 2 2 4 4 4 1 CPL (NUC119) domain PUF PF00806.19 GAX12303.1 - 5.6e-07 28.9 2.7 0.034 13.8 0.0 4.8 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DXP_synthase_N PF13292.6 GAX12303.1 - 0.05 12.8 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Utp13 PF08625.11 GAX12303.1 - 0.13 12.2 0.2 0.37 10.7 0.2 1.9 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain AIM5 PF17050.5 GAX12303.1 - 3.5 8.5 5.9 11 6.9 1.7 3.3 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 Heme_oxygenase PF01126.20 GAX12304.1 - 6e-08 32.7 0.1 8.7e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Heme oxygenase ATP-synt PF00231.19 GAX12305.1 - 1.4e-74 251.3 1.0 1.6e-74 251.2 1.0 1.0 1 0 0 1 1 1 1 ATP synthase Spt5_N PF11942.8 GAX12305.1 - 0.12 13.4 0.1 0.25 12.4 0.1 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ras PF00071.22 GAX12305.1 - 0.12 11.9 2.4 0.33 10.5 0.7 2.1 1 1 1 2 2 2 0 Ras family RPA_interact_C PF14768.6 GAX12306.1 - 7.8e-11 42.4 3.8 1.4e-10 41.6 3.8 1.4 1 0 0 1 1 1 1 Replication protein A interacting C-terminal DUF2313 PF10076.9 GAX12306.1 - 0.04 13.8 0.1 1.6 8.5 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) TLC PF03219.14 GAX12307.1 - 1.3e-05 24.1 9.3 3.2e-05 22.8 1.6 3.0 1 1 0 2 2 2 2 TLC ATP/ADP transporter Chloroa_b-bind PF00504.21 GAX12308.1 - 7e-34 117.7 0.0 9.3e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF1706 PF08020.11 GAX12309.1 - 0.029 14.3 0.8 0.048 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) Radical_SAM PF04055.21 GAX12310.1 - 6.3e-15 55.9 0.0 1.1e-14 55.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily YacG PF03884.14 GAX12310.1 - 0.18 11.6 0.4 0.57 10.0 0.3 1.9 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG LEA_6 PF10714.9 GAX12310.1 - 2.2 8.4 3.7 4.9 7.3 3.7 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 zf-HIT PF04438.16 GAX12311.1 - 1.8e-07 30.9 12.3 3.4e-07 30.0 12.3 1.5 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 GAX12311.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 GAX12311.1 - 0.05 13.7 8.7 0.13 12.4 8.4 1.9 1 1 0 1 1 1 0 MYND finger PolC_DP2 PF03833.13 GAX12311.1 - 0.94 7.3 10.9 0.0074 14.2 1.9 1.7 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 AAA PF00004.29 GAX12314.1 - 9.7e-31 106.9 0.0 1.9e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX12314.1 - 3.6e-07 30.7 0.0 7.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX12314.1 - 9.1e-06 26.0 0.2 7.6e-05 23.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX12314.1 - 1.1e-05 25.4 0.9 3.2e-05 23.9 0.9 1.8 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 GAX12314.1 - 0.00015 22.3 0.0 0.0003 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAX12314.1 - 0.00027 21.2 0.0 0.0006 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAX12314.1 - 0.00065 19.7 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAX12314.1 - 0.00095 19.5 0.0 0.0026 18.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 GAX12314.1 - 0.00096 18.4 0.0 0.0034 16.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAX12314.1 - 0.0015 18.3 0.0 0.012 15.3 0.0 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX12314.1 - 0.0028 17.8 0.0 0.0047 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX12314.1 - 0.0031 17.4 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAX12314.1 - 0.0038 17.0 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 GAX12314.1 - 0.0049 16.9 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 GAX12314.1 - 0.0095 15.7 0.1 0.022 14.5 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase AAA_14 PF13173.6 GAX12314.1 - 0.01 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAX12314.1 - 0.012 15.2 0.1 0.054 13.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX12314.1 - 0.013 15.3 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAX12314.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAX12314.1 - 0.033 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DnaB_C PF03796.15 GAX12314.1 - 0.055 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 GAX12314.1 - 0.063 13.6 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 GAX12314.1 - 0.071 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAX12314.1 - 0.074 12.4 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GAX12314.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain TIP49 PF06068.13 GAX12314.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain PhoH PF02562.16 GAX12314.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 GAX12314.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GAX12314.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RRM_1 PF00076.22 GAX12315.1 - 1.1e-34 118.1 0.0 2.4e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX12315.1 - 2.2e-16 59.8 0.1 8.9e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 GAX12315.1 - 0.0037 17.3 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Laminin_G_1 PF00054.23 GAX12315.1 - 0.061 13.5 0.0 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain PHM7_cyt PF14703.6 GAX12315.1 - 0.092 13.0 0.1 22 5.2 0.0 3.1 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 GAX12315.1 - 0.16 11.5 0.0 0.43 10.2 0.0 1.7 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.6 GAX12316.1 - 1.5e-05 24.9 0.0 5.6e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX12316.1 - 4.3e-05 24.1 0.0 0.00074 20.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX12316.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX12316.1 - 0.0002 22.0 0.0 0.00095 19.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 GAX12316.1 - 0.0085 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 GAX12316.1 - 0.056 14.2 0.0 0.29 11.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain TEX13 PF15186.6 GAX12316.1 - 0.43 10.2 8.0 0.57 9.8 3.0 3.0 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family RIO1 PF01163.22 GAX12317.1 - 1.5e-40 138.8 0.0 1.7e-30 106.0 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 GAX12317.1 - 1.2e-27 95.9 0.1 3.5e-27 94.4 0.1 1.8 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 GAX12317.1 - 2.5e-05 24.3 3.0 0.012 15.5 0.3 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAX12317.1 - 0.0021 17.4 0.1 0.15 11.4 0.1 2.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3525 PF12039.8 GAX12317.1 - 0.011 14.5 0.3 0.016 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) CENP-B_dimeris PF09026.10 GAX12317.1 - 0.1 13.0 14.1 0.27 11.6 14.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HopW1-1 PF15457.6 GAX12318.1 - 0.012 14.9 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA zf-CSL PF05207.13 GAX12318.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 CSL zinc finger adh_short PF00106.25 GAX12319.1 - 3.3e-35 121.3 0.0 4.6e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX12319.1 - 3.3e-20 72.6 0.0 5.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX12319.1 - 1.4e-13 51.2 0.0 3e-13 50.1 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAX12319.1 - 0.00081 19.3 0.6 0.0016 18.4 0.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAX12319.1 - 0.00093 18.4 0.2 0.0014 17.8 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 GAX12319.1 - 0.0015 18.8 0.7 0.0029 17.9 0.7 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 GAX12319.1 - 0.011 15.5 0.2 0.026 14.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.18 GAX12319.1 - 0.014 15.3 0.4 0.022 14.7 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.25 GAX12319.1 - 0.03 13.8 0.1 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 GAX12319.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAX12319.1 - 0.067 13.4 0.4 0.12 12.7 0.4 1.4 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.23 GAX12319.1 - 0.087 12.9 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Lon_C PF05362.13 GAX12319.1 - 0.1 12.1 0.4 0.18 11.3 0.4 1.3 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain DUF1776 PF08643.10 GAX12319.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 GAX12319.1 - 0.19 11.3 1.2 0.29 10.6 1.2 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.26 GAX12319.1 - 0.22 11.5 1.2 0.26 11.2 0.2 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HHH_5 PF14520.6 GAX12319.1 - 0.38 11.4 3.0 3.4 8.4 0.7 2.6 1 1 1 2 2 2 0 Helix-hairpin-helix domain THF_DHG_CYH PF00763.23 GAX12320.1 - 2.6e-22 79.3 0.0 4.5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAX12320.1 - 1.5e-15 56.9 0.6 4.3e-14 52.1 0.6 2.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 GAX12320.1 - 0.0017 17.7 0.0 0.0043 16.4 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX12321.1 - 2.3e-53 180.2 0.0 3.6e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX12321.1 - 5.5e-05 22.8 0.0 0.00012 21.7 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 GAX12321.1 - 0.0052 16.9 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 GAX12321.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAX12321.1 - 0.023 15.3 0.0 0.047 14.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.6 GAX12321.1 - 0.029 14.9 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_10 PF13460.6 GAX12321.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding ELFV_dehydrog PF00208.21 GAX12321.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 GAX12321.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain eRF1_2 PF03464.15 GAX12322.1 - 2.4e-45 154.1 0.0 3.9e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAX12322.1 - 3.4e-36 124.1 0.2 8e-36 123.0 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 GAX12322.1 - 7e-22 77.8 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 GAX12322.1 - 1.9e-10 41.1 0.0 3.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 GAX12322.1 - 7.2e-08 32.8 0.0 1.2e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 PTSIIB_sorb PF03830.15 GAX12322.1 - 0.081 13.1 0.6 8.4 6.6 0.1 2.2 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component Gp45_2 PF17470.2 GAX12322.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Phage gene product 45.2 Lipase_GDSL_2 PF13472.6 GAX12323.1 - 9.8e-07 29.3 0.0 3.6e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX12323.1 - 0.0078 16.2 0.0 0.04 13.9 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PPR_2 PF13041.6 GAX12325.1 - 3.2e-29 100.9 4.5 0.00046 20.3 0.1 9.2 9 0 0 9 9 9 7 PPR repeat family PPR_1 PF12854.7 GAX12325.1 - 4.9e-26 90.1 3.7 0.00089 18.9 0.0 10.8 11 2 0 11 11 11 6 PPR repeat PPR_3 PF13812.6 GAX12325.1 - 1.4e-16 60.3 0.0 0.0035 17.4 0.0 8.1 3 3 5 9 9 9 5 Pentatricopeptide repeat domain PPR PF01535.20 GAX12325.1 - 8.8e-14 50.7 21.4 8.4e-06 25.7 0.0 9.9 12 2 0 12 12 12 4 PPR repeat PPR_long PF17177.4 GAX12325.1 - 1.9e-11 43.8 6.3 4.2e-06 26.3 0.3 3.7 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP Annexin_like PF18411.1 GAX12325.1 - 1.5e-05 25.2 0.3 0.011 15.9 0.0 4.3 3 1 0 4 4 4 1 Annexin-like domain LPD11 PF18824.1 GAX12325.1 - 0.013 15.5 0.0 0.77 9.9 0.0 2.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Wzy_C_2 PF11846.8 GAX12325.1 - 0.13 12.2 4.0 15 5.4 0.1 4.2 3 3 3 6 6 6 0 Virulence factor membrane-bound polymerase, C-terminal Ribosomal_L11 PF00298.19 GAX12327.1 - 5.6e-22 78.0 0.0 7.7e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAX12327.1 - 9e-22 76.7 0.0 1.7e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Proteasome PF00227.26 GAX12329.1 - 3.2e-49 167.0 0.2 3.8e-49 166.8 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit FaeA PF04703.12 GAX12329.1 - 0.12 12.8 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 FaeA-like protein Lipase_3 PF01764.25 GAX12330.1 - 2.2e-21 76.2 0.0 3.5e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PAP_fibrillin PF04755.12 GAX12331.1 - 0.0023 17.9 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin TH1 PF04858.13 GAX12332.1 - 1.5e-45 156.0 0.1 2.7e-27 95.7 0.1 2.3 2 0 0 2 2 2 2 TH1 protein WW PF00397.26 GAX12332.1 - 9.5e-21 73.6 15.4 3e-11 43.2 3.7 2.6 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 GAX12332.1 - 0.8 10.0 7.4 8 6.8 2.2 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain ABC_membrane PF00664.23 GAX12333.1 - 1.1e-59 202.4 22.6 7.6e-30 104.5 11.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX12333.1 - 2.7e-20 73.3 0.2 3e-18 66.7 0.0 2.8 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 GAX12333.1 - 9.2e-06 25.7 0.2 2.4e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GAX12333.1 - 0.00097 19.2 1.2 0.0023 18.0 1.2 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAX12333.1 - 0.0014 18.7 0.4 0.0038 17.3 0.4 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 GAX12333.1 - 0.0041 16.6 1.3 0.055 12.9 0.5 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX12333.1 - 0.0099 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.16 GAX12333.1 - 0.03 13.6 0.4 0.069 12.5 0.4 1.6 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 GAX12333.1 - 0.11 12.8 0.4 0.38 11.1 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 GAX12333.1 - 0.13 11.8 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SBP_bac_5 PF00496.22 GAX12334.1 - 6.7e-38 130.6 0.0 4.9e-33 114.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle YrhC PF14143.6 GAX12334.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 YrhC-like protein FAD_binding_8 PF08022.12 GAX12335.1 - 4.9e-12 45.9 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 GAX12335.1 - 1.8e-08 34.7 0.0 0.003 17.7 0.1 2.7 2 1 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAX12335.1 - 6.6e-07 29.5 2.4 1.6e-06 28.2 2.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 GAX12335.1 - 0.00061 20.4 0.0 0.069 13.8 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain C1_1 PF00130.22 GAX12336.1 - 0.00019 21.2 9.3 0.00037 20.3 9.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pex24p PF06398.11 GAX12336.1 - 0.016 14.2 0.2 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Reticulon PF02453.17 GAX12336.1 - 0.027 14.5 1.2 3.1 7.7 0.2 2.3 2 0 0 2 2 2 0 Reticulon C2 PF00168.30 GAX12336.1 - 0.037 14.3 0.0 3.3 8.0 0.0 3.3 3 0 0 3 3 3 0 C2 domain C1_2 PF03107.16 GAX12336.1 - 0.9 9.9 8.5 2.1 8.7 8.5 1.6 1 0 0 1 1 1 0 C1 domain PRT_C PF08372.10 GAX12336.1 - 4.6 7.0 4.8 16 5.2 0.2 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DEAD PF00270.29 GAX12337.1 - 1.8e-47 161.4 0.0 1.5e-46 158.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12337.1 - 9.2e-26 90.4 0.0 2.7e-25 88.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAX12337.1 - 0.0002 20.6 0.0 0.00041 19.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAX12337.1 - 0.0081 16.2 0.0 0.035 14.1 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF2381 PF09544.10 GAX12337.1 - 0.021 14.3 5.1 0.045 13.3 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) SecA_DEAD PF07517.14 GAX12337.1 - 0.085 12.1 0.0 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain SET PF00856.28 GAX12338.1 - 1.4e-19 71.1 0.4 1.4e-19 71.1 0.4 3.0 3 1 0 3 3 3 1 SET domain N-SET PF11764.8 GAX12338.1 - 0.042 14.0 4.6 0.11 12.6 4.6 1.6 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N CCDC71L PF15374.6 GAX12338.1 - 0.069 12.4 1.5 0.14 11.4 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF1751 PF08551.10 GAX12339.1 - 1.5e-05 25.5 2.9 1.5e-05 25.5 2.9 1.6 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 GAX12339.1 - 0.00013 22.0 9.3 0.00024 21.1 9.3 1.4 1 0 0 1 1 1 1 Rhomboid family Isy1 PF06246.12 GAX12340.1 - 4.8e-72 242.6 8.1 4.2e-70 236.2 8.1 2.0 1 1 0 1 1 1 1 Isy1-like splicing family Atg14 PF10186.9 GAX12340.1 - 0.14 11.3 0.8 0.19 10.8 0.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YolD PF08863.10 GAX12340.1 - 0.14 12.3 0.3 0.14 12.3 0.3 1.8 2 0 0 2 2 2 0 YolD-like protein Choline_transpo PF04515.12 GAX12341.1 - 9.9e-63 212.3 7.4 9.9e-63 212.3 7.4 2.3 1 1 1 2 2 2 1 Plasma-membrane choline transporter PTRF_SDPR PF15237.6 GAX12341.1 - 0.037 13.7 0.7 0.061 13.0 0.7 1.2 1 0 0 1 1 1 0 PTRF/SDPR family DUF2418 PF10332.9 GAX12341.1 - 1.9 9.1 7.6 1.5 9.4 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2418) Pox_P21 PF05313.12 GAX12341.1 - 4.4 6.8 7.7 0.34 10.5 2.3 1.9 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Mannosyl_trans2 PF04188.13 GAX12342.1 - 4.1e-36 125.3 21.0 1.1e-34 120.5 19.7 2.8 2 1 0 2 2 2 1 Mannosyltransferase (PIG-V) ABC1 PF03109.16 GAX12343.1 - 9.6e-30 103.2 0.0 2.2e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX12343.1 - 8.9e-05 22.5 1.7 0.00083 19.3 1.7 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX12343.1 - 0.0075 15.7 0.1 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain ClpS PF02617.17 GAX12344.1 - 9.3e-17 60.6 0.5 1.4e-16 60.1 0.1 1.5 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS CCDC106 PF15794.5 GAX12344.1 - 0.011 15.4 0.8 0.015 15.0 0.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 G10 PF01125.17 GAX12344.1 - 0.018 14.8 0.2 0.022 14.5 0.2 1.1 1 0 0 1 1 1 0 G10 protein CCDC32 PF14989.6 GAX12344.1 - 0.04 13.9 0.2 0.052 13.5 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing 32 DUF3774 PF12609.8 GAX12344.1 - 0.076 14.0 0.4 0.16 13.0 0.4 1.5 1 0 0 1 1 1 0 Wound-induced protein PfkB PF00294.24 GAX12345.1 - 2.4e-47 161.7 4.7 4e-47 161.0 4.7 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GAX12345.1 - 7e-07 28.9 0.0 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Cation_efflux PF01545.21 GAX12346.1 - 2.1e-28 99.4 7.0 2.6e-28 99.1 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAX12346.1 - 1.5e-09 37.8 0.1 3.2e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Chordopox_A13L PF05961.11 GAX12346.1 - 0.001 19.2 0.0 0.055 13.7 0.0 2.5 2 0 0 2 2 2 1 Chordopoxvirus A13L protein DUF386 PF04074.12 GAX12346.1 - 0.084 12.8 0.3 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 YhcH/YjgK/YiaL MAPEG PF01124.18 GAX12346.1 - 0.087 12.7 0.9 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 MAPEG family DEAD PF00270.29 GAX12347.1 - 8.5e-24 84.3 0.0 2.1e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12347.1 - 5.2e-05 23.5 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX12347.1 - 0.00062 19.8 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAX12347.1 - 0.013 15.9 0.0 0.039 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain SAP PF02037.27 GAX12347.1 - 0.044 13.6 0.2 0.16 11.8 0.2 1.9 1 0 0 1 1 1 0 SAP domain CLP1_P PF16575.5 GAX12348.1 - 9.6e-46 156.0 0.0 1.7e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 GAX12348.1 - 5.7e-24 84.8 0.1 9.5e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 GAX12348.1 - 1.9e-20 72.9 0.0 3.5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 GAX12348.1 - 0.00061 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 GAX12348.1 - 0.003 17.9 0.0 0.0068 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.7 GAX12348.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_35 PF14516.6 GAX12348.1 - 0.029 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.18 GAX12348.1 - 0.037 13.4 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 GAX12348.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX12348.1 - 0.063 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 GAX12348.1 - 0.078 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAX12348.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 GAX12348.1 - 0.094 12.2 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CbiA PF01656.23 GAX12348.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rpn9_C PF18261.1 GAX12348.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix TPR_12 PF13424.6 GAX12349.1 - 1.3e-30 105.4 1.6 2.3e-11 43.8 0.2 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX12349.1 - 1.3e-27 94.8 1.1 1.1e-05 25.1 0.0 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX12349.1 - 4.6e-22 76.3 1.0 0.0033 17.4 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX12349.1 - 5.7e-19 67.1 2.8 0.0014 18.3 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX12349.1 - 1.8e-10 40.1 9.7 0.063 13.5 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX12349.1 - 2.2e-09 37.3 5.6 0.71 10.9 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX12349.1 - 2.2e-07 31.4 2.6 0.68 10.6 0.0 5.4 4 1 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX12349.1 - 2.1e-06 27.1 1.0 0.026 14.0 0.0 4.0 4 0 0 4 4 4 1 SHNi-TPR TPR_7 PF13176.6 GAX12349.1 - 2.5e-06 27.1 3.9 0.011 15.7 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX12349.1 - 2.2e-05 24.5 0.4 0.61 10.2 0.0 3.6 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 GAX12349.1 - 3.8e-05 24.1 5.0 0.48 11.0 0.1 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX12349.1 - 5.8e-05 22.6 0.0 0.0024 17.3 0.0 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 GAX12349.1 - 6e-05 23.4 1.5 19 6.2 0.0 5.4 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX12349.1 - 0.00026 20.6 1.1 4.6 7.0 0.0 5.7 6 0 0 6 6 6 1 TPR repeat Coatomer_E PF04733.14 GAX12349.1 - 0.054 12.9 3.6 6.6 6.1 0.1 4.4 2 2 0 4 4 4 0 Coatomer epsilon subunit DUF5601 PF18151.1 GAX12349.1 - 0.13 12.6 0.0 6.7 7.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) TPR_9 PF13371.6 GAX12349.1 - 5.3 7.3 6.6 2.9 8.1 0.6 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat tRNA-synt_1b PF00579.25 GAX12351.1 - 9.2e-79 264.8 0.0 1.1e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Elongin_A PF06881.11 GAX12351.1 - 0.081 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF1281 PF06924.11 GAX12352.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1281) ABC_tran PF00005.27 GAX12353.1 - 2.4e-44 151.2 6.3 2.8e-22 79.7 0.0 3.8 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 GAX12353.1 - 6.4e-14 52.5 14.9 7.8e-05 22.6 0.0 5.3 3 2 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX12353.1 - 1.9e-09 37.3 9.9 0.015 14.8 0.0 4.4 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAX12353.1 - 3.7e-07 30.2 0.0 0.0017 18.3 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAX12353.1 - 3.7e-07 29.8 0.2 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAX12353.1 - 7.6e-05 23.2 0.1 0.39 11.2 0.1 3.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAX12353.1 - 0.00017 22.0 0.0 0.42 11.0 0.0 3.2 2 0 0 2 2 2 2 RNA helicase ABC_tran_Xtn PF12848.7 GAX12353.1 - 0.00018 21.4 10.0 0.00018 21.4 10.0 6.7 7 1 0 7 7 4 1 ABC transporter AAA_33 PF13671.6 GAX12353.1 - 0.00056 20.1 0.1 0.21 11.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 GAX12353.1 - 0.00069 19.7 5.0 0.027 14.5 0.0 4.0 4 1 0 4 4 4 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAX12353.1 - 0.0011 19.3 2.5 0.47 10.7 0.0 3.6 4 0 0 4 4 2 1 AAA domain AAA_14 PF13173.6 GAX12353.1 - 0.0017 18.4 0.2 1.8 8.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 GAX12353.1 - 0.002 18.4 7.4 0.39 11.0 0.0 3.8 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 GAX12353.1 - 0.003 17.5 0.1 0.94 9.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 GAX12353.1 - 0.0038 16.8 0.0 0.86 9.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 GAX12353.1 - 0.004 17.5 7.5 0.19 12.1 0.0 4.0 5 0 0 5 5 3 2 AAA ATPase domain AAA_23 PF13476.6 GAX12353.1 - 0.0058 17.1 2.5 0.0058 17.1 2.5 6.2 6 2 0 6 6 4 2 AAA domain AAA_5 PF07728.14 GAX12353.1 - 0.011 15.7 1.4 1 9.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 GAX12353.1 - 0.011 15.4 0.1 0.011 15.4 0.1 5.8 4 1 2 6 6 5 0 AAA ATPase domain AAA_24 PF13479.6 GAX12353.1 - 0.013 15.2 8.3 0.47 10.1 0.1 4.1 3 1 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 GAX12353.1 - 0.024 14.0 0.1 15 4.9 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAX12353.1 - 0.37 11.3 0.0 0.37 11.3 0.0 4.3 4 0 0 4 4 2 0 AAA domain Dynamin_N PF00350.23 GAX12353.1 - 0.93 9.5 0.0 0.93 9.5 0.0 4.9 4 2 0 4 4 3 0 Dynamin family Adaptin_binding PF10199.9 GAX12353.1 - 2.6 8.7 0.0 2.6 8.7 0.0 6.2 3 2 2 5 5 3 0 Alpha and gamma adaptin binding protein p34 Polyketide_cyc2 PF10604.9 GAX12354.1 - 0.00029 21.1 0.0 0.0011 19.2 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX12354.1 - 0.00047 20.4 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport REV PF00424.18 GAX12354.1 - 0.32 11.0 2.0 1 9.5 2.0 1.8 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Mito_carr PF00153.27 GAX12355.1 - 1.3e-67 223.8 5.1 1.1e-23 82.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TCR PF03638.15 GAX12357.1 - 2.9e-22 78.7 48.1 7.8e-12 45.3 17.8 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.7 GAX12357.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF5582 PF17819.1 GAX12357.1 - 0.007 16.8 0.1 0.021 15.3 0.1 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5582) F-box PF00646.33 GAX12357.1 - 0.0091 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 F-box domain MSL2-CXC PF16682.5 GAX12357.1 - 0.83 9.8 37.6 1.1 9.4 15.4 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Sec10 PF07393.11 GAX12358.1 - 1.4e-18 66.7 0.0 1.9e-09 36.6 0.0 2.4 2 1 0 2 2 2 2 Exocyst complex component Sec10 RINT1_TIP1 PF04437.13 GAX12358.1 - 0.0076 15.2 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF3231 PF11553.8 GAX12358.1 - 0.034 13.8 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) Tricorn_C1 PF14684.6 GAX12358.1 - 0.06 13.4 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Tricorn protease C1 domain zf-RanBP PF00641.18 GAX12359.1 - 0.00063 19.0 1.8 0.00063 19.0 1.8 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others HD_assoc PF13286.6 GAX12359.1 - 0.072 13.6 0.8 0.22 12.0 0.0 2.1 2 1 0 2 2 2 0 Phosphohydrolase-associated domain YabA PF06156.13 GAX12359.1 - 0.44 11.2 3.2 1.2 9.8 3.2 1.7 1 0 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 GAX12359.1 - 1.2 9.2 7.9 2.1 8.4 7.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PriA_CRR PF18319.1 GAX12359.1 - 2.3 8.3 6.2 0.19 11.7 0.7 2.0 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain PRC2_HTH_1 PF18118.1 GAX12359.1 - 3.7 8.4 6.3 3.5 8.5 0.5 2.4 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain ATG16 PF08614.11 GAX12359.1 - 7 6.8 13.5 20 5.3 13.5 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-RanBP PF00641.18 GAX12360.1 - 0.00037 19.8 3.0 0.0012 18.2 3.0 2.0 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SAE2 PF08573.10 GAX12360.1 - 0.0031 18.6 1.2 0.0031 18.6 1.2 4.6 3 2 1 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Linker_histone PF00538.19 GAX12362.1 - 1.4e-17 63.8 2.4 1.4e-17 63.8 2.4 2.3 1 1 2 3 3 3 1 linker histone H1 and H5 family Spc7_N PF15402.6 GAX12362.1 - 0.24 9.6 17.1 0.25 9.6 17.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF356 PF04009.12 GAX12362.1 - 0.61 10.4 7.8 0.082 13.2 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF356) Mucin PF01456.17 GAX12362.1 - 3.9 7.5 15.5 5.3 7.0 15.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF572 PF04502.13 GAX12362.1 - 9.5 5.7 19.8 11 5.6 19.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ank_2 PF12796.7 GAX12363.1 - 4e-14 53.0 0.0 1.9e-05 25.2 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX12363.1 - 8.7e-11 41.1 1.5 0.022 15.3 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 GAX12363.1 - 6e-08 33.1 0.2 1.2 9.8 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX12363.1 - 1.2e-07 31.9 0.8 0.0013 19.0 0.1 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX12363.1 - 6.5e-07 29.5 3.8 0.41 11.2 0.1 5.2 6 0 0 6 6 6 2 Ankyrin repeat MOR2-PAG1_C PF14225.6 GAX12363.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Cell morphogenesis C-terminal OCD_Mu_crystall PF02423.15 GAX12364.1 - 1.3e-49 168.9 0.4 1.7e-49 168.5 0.4 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_2 PF03446.15 GAX12364.1 - 0.0061 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 GAX12364.1 - 0.05 13.0 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAX12364.1 - 0.067 13.8 0.1 0.15 12.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TPR_1 PF00515.28 GAX12366.1 - 2.5e-36 122.0 7.3 9.5e-06 25.2 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX12366.1 - 4.6e-34 113.8 8.0 7e-06 25.8 0.3 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAX12366.1 - 3.1e-22 78.0 4.9 0.0011 18.6 0.0 6.4 4 2 2 6 6 6 5 TPR repeat TPR_8 PF13181.6 GAX12366.1 - 9.9e-17 59.7 10.7 0.0035 17.4 0.1 7.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX12366.1 - 9.3e-15 55.0 4.3 0.028 15.1 0.3 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX12366.1 - 2e-13 49.3 1.9 0.0044 17.0 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX12366.1 - 1.1e-12 48.0 8.8 0.0013 19.0 0.2 5.0 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAX12366.1 - 1.4e-11 44.7 6.7 0.0068 16.9 0.0 5.5 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX12366.1 - 5.8e-10 39.1 4.7 0.00079 19.9 0.1 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX12366.1 - 3.2e-08 33.4 10.5 1.9 9.0 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX12366.1 - 4.9e-08 33.2 0.2 2.8 9.0 0.2 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX12366.1 - 6.4e-07 29.4 2.3 0.03 14.5 0.1 4.3 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX12366.1 - 0.00014 21.6 8.7 1.2 9.1 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_3 PF07720.12 GAX12366.1 - 0.00029 20.7 4.7 1.5 8.9 0.2 5.3 6 0 0 6 6 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX12366.1 - 0.0016 17.8 2.6 3 7.4 0.0 4.1 5 0 0 5 5 4 2 SHNi-TPR Fis1_TPR_C PF14853.6 GAX12366.1 - 0.0024 17.9 4.7 0.14 12.3 0.4 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 GAX12366.1 - 0.033 14.3 14.7 1.9 8.6 0.4 4.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.15 GAX12366.1 - 0.061 13.4 4.6 19 5.3 0.0 3.6 3 1 0 3 3 2 0 MAS20 protein import receptor ANAPC3 PF12895.7 GAX12366.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.7 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 HemY_N PF07219.13 GAX12366.1 - 0.42 10.8 6.5 1.5 9.1 0.2 3.4 3 0 0 3 3 3 0 HemY protein N-terminus DUF3856 PF12968.7 GAX12366.1 - 0.96 9.5 7.5 2.2 8.4 0.1 3.6 4 1 0 4 4 3 0 Domain of Unknown Function (DUF3856) DUF5113 PF17140.4 GAX12366.1 - 1.2 9.0 8.8 1.1 9.1 0.2 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF5113) BTAD PF03704.17 GAX12366.1 - 4.8 7.6 9.8 23 5.4 0.3 4.2 4 1 1 5 5 5 0 Bacterial transcriptional activator domain TOM20_plant PF06552.12 GAX12366.1 - 6.3 6.5 7.8 17 5.1 0.1 4.2 4 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 tRNA-synt_1 PF00133.22 GAX12367.1 - 1.8e-36 125.6 0.0 1.8e-23 82.7 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAX12367.1 - 6.4e-18 64.7 0.3 6.4e-08 31.7 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAX12367.1 - 8.9e-14 51.7 0.2 2e-13 50.5 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GAX12367.1 - 1.2e-05 24.8 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Hpt PF01627.23 GAX12368.1 - 1.7e-08 34.6 1.5 2.5e-08 34.0 1.5 1.3 1 0 0 1 1 1 1 Hpt domain HSCB_C PF07743.13 GAX12368.1 - 0.023 15.2 1.8 0.034 14.6 0.2 1.9 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain INT_SG_DDX_CT_C PF15300.6 GAX12368.1 - 0.072 12.9 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus TPR_21 PF09976.9 GAX12368.1 - 0.13 12.0 2.8 0.16 11.7 2.6 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain CBS PF00571.28 GAX12369.1 - 9.7e-25 86.8 0.0 1.3e-07 31.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain RICTOR_V PF14668.6 GAX12370.1 - 0.0076 16.5 0.2 0.022 15.0 0.1 1.7 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3770 PF12603.8 GAX12370.1 - 0.0099 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3770) LRR_6 PF13516.6 GAX12370.1 - 0.061 13.4 0.1 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeat Aminotran_4 PF01063.19 GAX12371.1 - 3.1e-24 86.1 0.0 7.7e-24 84.8 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV Pro_isomerase PF00160.21 GAX12372.1 - 2.1e-44 151.6 0.1 2.5e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-patch PF01585.23 GAX12373.1 - 2.6e-14 52.8 0.7 6.2e-14 51.6 0.7 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAX12373.1 - 1.1e-07 31.8 0.2 1.1e-07 31.8 0.2 2.8 3 0 0 3 3 3 1 G-patch domain HSF_DNA-bind PF00447.17 GAX12374.1 - 4.5e-18 65.6 0.1 9.4e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding LYTB PF02401.18 GAX12375.1 - 1.9e-76 256.8 0.5 2.4e-76 256.5 0.5 1.1 1 0 0 1 1 1 1 LytB protein SEP PF08059.13 GAX12376.1 - 2.2e-19 69.8 0.0 4.1e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 GAX12376.1 - 2e-09 37.5 0.0 2.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain Rad21_Rec8_N PF04825.13 GAX12377.1 - 3e-38 130.4 0.0 5.1e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAX12377.1 - 1.1e-12 47.1 0.0 4.2e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein FUN14 PF04930.15 GAX12379.1 - 1e-24 86.8 2.3 1.9e-24 85.9 2.3 1.5 1 0 0 1 1 1 1 FUN14 family EF-hand_5 PF13202.6 GAX12379.1 - 0.013 14.9 1.2 0.035 13.6 1.2 1.7 1 0 0 1 1 1 0 EF hand His_Phos_1 PF00300.22 GAX12380.1 - 1.8e-34 119.2 0.0 2.9e-26 92.4 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) GlnE PF03710.15 GAX12380.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase JmjC PF02373.22 GAX12382.1 - 1.5e-20 73.7 1.6 2e-20 73.3 0.1 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GAX12382.1 - 2e-17 63.8 0.1 4e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain HupE_UreJ_2 PF13795.6 GAX12383.1 - 0.14 11.8 9.6 0.063 12.9 1.6 2.8 2 1 1 3 3 3 0 HupE / UreJ protein COPI_assoc PF08507.10 GAX12383.1 - 0.21 11.6 0.3 0.21 11.6 0.3 2.6 2 1 0 2 2 2 0 COPI associated protein MerE PF05052.12 GAX12383.1 - 0.28 11.1 6.1 0.051 13.5 1.3 2.2 2 0 0 2 2 2 0 MerE protein Prefoldin PF02996.17 GAX12385.1 - 5.5e-10 39.2 0.0 8.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4635 PF15466.6 GAX12385.1 - 0.085 12.4 0.3 0.64 9.5 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4635) eIF-1a PF01176.19 GAX12386.1 - 1.3e-11 44.2 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TMEM164 PF14808.6 GAX12388.1 - 0.098 12.0 7.0 0.33 10.3 7.0 1.8 1 1 0 1 1 1 0 TMEM164 family Aminotran_1_2 PF00155.21 GAX12389.1 - 5.6e-59 200.1 0.0 6.7e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX12389.1 - 1e-05 24.2 0.0 1.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 GAX12389.1 - 0.0064 15.3 0.1 0.0092 14.8 0.1 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Met_gamma_lyase PF06838.11 GAX12389.1 - 0.011 14.3 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Aminotran_5 PF00266.19 GAX12389.1 - 0.02 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V AAA_23 PF13476.6 GAX12390.1 - 0.0065 17.0 1.6 0.011 16.2 1.6 1.5 1 0 0 1 1 1 1 AAA domain TAP42 PF04177.12 GAX12390.1 - 0.016 14.3 5.8 0.028 13.6 5.8 1.3 1 0 0 1 1 1 0 TAP42-like family SPACA9 PF15120.6 GAX12390.1 - 0.026 14.3 0.3 0.044 13.6 0.3 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Laminin_II PF06009.12 GAX12390.1 - 0.23 11.5 11.9 0.67 10.0 8.0 2.2 2 0 0 2 2 2 0 Laminin Domain II Get5_C PF18514.1 GAX12390.1 - 0.66 9.7 0.1 0.66 9.7 0.1 2.8 4 0 0 4 4 4 0 Get5 C-terminal domain Atg14 PF10186.9 GAX12390.1 - 2.5 7.1 8.8 3.7 6.5 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4481 PF14800.6 GAX12390.1 - 2.8 7.3 5.2 4.3 6.7 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) TMPIT PF07851.13 GAX12390.1 - 4.5 6.4 5.5 6.8 5.8 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein WD40 PF00400.32 GAX12391.1 - 0.0004 21.1 0.2 0.16 12.9 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX12391.1 - 0.0059 16.9 0.0 0.037 14.3 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX12391.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TLC PF03219.14 GAX12392.1 - 3.3e-05 22.8 7.6 4.9e-05 22.2 0.1 2.7 1 1 2 3 3 3 2 TLC ATP/ADP transporter FCSD-flav_bind PF09242.11 GAX12392.1 - 0.019 15.3 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding TMF_DNA_bd PF12329.8 GAX12393.1 - 0.00035 20.5 15.2 0.00035 20.5 15.2 6.5 3 2 2 5 5 5 1 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 GAX12393.1 - 0.0048 16.3 60.7 0.14 11.5 22.3 3.1 1 1 0 2 2 2 2 FAM76 protein Spc7 PF08317.11 GAX12393.1 - 0.19 10.6 53.9 0.66 8.8 18.3 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 GAX12393.1 - 3.2 7.0 55.9 0.16 11.3 28.5 3.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMEM213 PF15192.6 GAX12394.1 - 0.0022 17.9 0.8 0.13 12.2 0.1 2.6 2 0 0 2 2 2 2 TMEM213 family 2-oxoacid_dh PF00198.23 GAX12395.1 - 6.2e-60 202.5 0.0 1e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX12395.1 - 1.3e-35 121.1 13.8 1.2e-18 66.7 5.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 GAX12395.1 - 1.9e-28 98.5 2.4 2.3e-15 56.6 0.1 2.9 2 0 0 2 2 2 2 e3 binding domain HlyD_3 PF13437.6 GAX12395.1 - 2.2e-05 25.1 5.5 0.36 11.5 0.3 4.4 3 2 1 4 4 4 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 GAX12395.1 - 2.7e-05 23.9 0.1 0.39 10.6 0.0 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like QRPTase_N PF02749.16 GAX12395.1 - 0.00049 20.1 0.4 0.96 9.5 0.0 3.8 3 1 1 4 4 4 2 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 GAX12395.1 - 0.00086 19.2 2.6 0.23 11.4 0.3 2.5 2 0 0 2 2 2 2 Glycine cleavage H-protein DUF2118 PF09891.9 GAX12395.1 - 0.058 13.4 0.1 2.5 8.0 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PYNP_C PF07831.13 GAX12395.1 - 0.064 12.9 0.3 15 5.3 0.1 3.2 2 1 1 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain FabA PF07977.13 GAX12396.1 - 1.6e-32 112.0 0.0 2.5e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 GAX12396.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain IlvC PF01450.19 GAX12397.1 - 4.2e-42 143.8 0.2 1.6e-32 112.8 0.1 2.4 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 GAX12397.1 - 9.5e-34 116.3 0.0 1.9e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1877 PF08974.10 GAX12397.1 - 0.0074 16.4 0.1 0.013 15.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) CbiJ PF02571.14 GAX12397.1 - 0.052 13.0 0.0 0.6 9.5 0.0 2.4 3 0 0 3 3 3 0 Precorrin-6x reductase CbiJ/CobK SSL_OB PF09199.10 GAX12397.1 - 0.15 12.4 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 Staphylococcal superantigen-like OB-fold domain Got1 PF04178.12 GAX12398.1 - 3.5e-10 40.3 7.9 5.2e-10 39.7 7.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Radical_SAM PF04055.21 GAX12399.1 - 1.5e-08 35.2 0.3 8.1e-08 32.8 0.1 2.4 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 GAX12399.1 - 2.3e-05 24.5 0.0 6.9e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 GAX12399.1 - 0.069 13.4 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain VPS28 PF03997.12 GAX12399.1 - 0.091 12.4 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 VPS28 protein YjcB PF15940.5 GAX12399.1 - 0.29 11.3 1.0 24 5.2 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function Pkinase PF00069.25 GAX12400.1 - 2.7e-06 27.0 0.0 9.9e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12400.1 - 0.0038 16.6 0.0 0.0046 16.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase AAA_5 PF07728.14 GAX12401.1 - 3e-100 331.8 0.0 3.3e-17 62.8 0.0 9.4 8 1 1 9 9 9 8 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX12401.1 - 7.2e-22 78.6 11.6 3.3e-05 24.3 0.3 7.1 6 0 0 6 6 5 5 AAA ATPase domain Dynein_heavy PF03028.15 GAX12401.1 - 9.4e-22 77.3 0.0 0.033 14.3 0.0 7.6 6 1 1 7 7 7 5 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 GAX12401.1 - 1.2e-20 74.3 0.0 0.00079 19.9 0.0 6.4 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 GAX12401.1 - 2.4e-19 69.4 0.0 1.2e-18 67.1 0.0 2.4 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 GAX12401.1 - 4.1e-19 68.7 0.0 8.4e-12 45.1 0.0 5.8 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 GAX12401.1 - 5.2e-19 68.4 0.7 1.1e-07 32.0 0.2 4.2 4 0 0 4 4 2 2 Midasin AAA lid domain AAA_7 PF12775.7 GAX12401.1 - 2.4e-18 66.3 0.4 4.8e-05 22.9 0.1 5.7 5 0 0 5 5 5 4 P-loop containing dynein motor region AAA_18 PF13238.6 GAX12401.1 - 2.7e-15 57.1 0.4 0.044 14.3 0.0 6.8 5 0 0 5 5 5 4 AAA domain TsaE PF02367.17 GAX12401.1 - 2e-14 53.7 0.9 0.1 12.6 0.0 5.6 5 0 0 5 5 5 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 GAX12401.1 - 3.4e-13 50.0 4.9 0.076 13.3 0.0 6.9 6 0 0 6 6 5 3 AAA domain Sigma54_activat PF00158.26 GAX12401.1 - 1.1e-12 48.0 0.0 0.22 11.2 0.0 5.7 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_33 PF13671.6 GAX12401.1 - 2.2e-12 47.3 0.7 0.12 12.5 0.1 6.0 5 0 0 5 5 5 3 AAA domain AAA_14 PF13173.6 GAX12401.1 - 5.3e-12 45.9 0.0 0.055 13.5 0.0 6.7 7 0 0 7 7 6 2 AAA domain AAA_30 PF13604.6 GAX12401.1 - 5.5e-12 45.8 0.2 0.026 14.3 0.0 7.1 6 1 0 6 6 6 2 AAA domain RsgA_GTPase PF03193.16 GAX12401.1 - 3.2e-11 43.4 0.1 0.55 10.1 0.1 5.8 5 0 0 5 5 5 2 RsgA GTPase Zeta_toxin PF06414.12 GAX12401.1 - 1.3e-09 37.7 0.0 0.31 10.3 0.0 5.2 5 0 0 5 5 5 2 Zeta toxin AAA_29 PF13555.6 GAX12401.1 - 2.3e-09 36.8 5.5 0.41 10.4 0.0 6.2 6 0 0 6 6 5 2 P-loop containing region of AAA domain AAA_28 PF13521.6 GAX12401.1 - 4e-09 36.9 4.7 0.37 11.0 0.1 5.7 5 0 0 5 5 5 2 AAA domain NACHT PF05729.12 GAX12401.1 - 4.2e-09 36.5 3.8 0.12 12.3 0.0 6.0 8 0 0 8 8 4 3 NACHT domain AAA_6 PF12774.7 GAX12401.1 - 1.1e-07 31.1 1.4 0.39 9.6 0.0 6.3 7 0 0 7 7 6 1 Hydrolytic ATP binding site of dynein motor region Mg_chelatase PF01078.21 GAX12401.1 - 1.4e-07 31.1 1.9 2.3 7.5 0.1 7.8 7 1 0 7 7 7 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 GAX12401.1 - 2.9e-07 29.9 0.4 0.14 11.3 0.0 5.1 5 0 0 5 5 5 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 GAX12401.1 - 3.4e-07 30.5 0.2 0.025 14.7 0.0 5.3 5 0 0 5 5 4 1 Sigma-54 interaction domain T2SSE PF00437.20 GAX12401.1 - 8.8e-07 28.3 0.5 1.8 7.5 0.0 4.7 5 0 0 5 5 4 1 Type II/IV secretion system protein RNA_helicase PF00910.22 GAX12401.1 - 1.1e-06 28.9 0.0 6.1 7.3 0.0 5.6 5 0 0 5 5 5 0 RNA helicase ABC_tran PF00005.27 GAX12401.1 - 2.2e-06 28.2 20.4 0.006 17.1 0.0 6.9 6 1 0 6 6 5 2 ABC transporter AAA_25 PF13481.6 GAX12401.1 - 2.6e-06 27.2 3.1 0.61 9.6 0.0 5.8 6 0 0 6 6 6 2 AAA domain Rad17 PF03215.15 GAX12401.1 - 6.7e-06 26.1 2.2 0.92 9.4 0.1 5.7 6 0 0 6 6 5 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 GAX12401.1 - 1.5e-05 25.0 3.4 10 6.2 0.0 6.2 6 0 0 6 6 6 0 50S ribosome-binding GTPase SRP54 PF00448.22 GAX12401.1 - 1.6e-05 24.6 0.0 2.2 7.8 0.0 4.7 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 GAX12401.1 - 1.6e-05 24.9 0.0 5.9 6.7 0.0 5.4 5 0 0 5 5 5 0 ATPase domain predominantly from Archaea VWA_2 PF13519.6 GAX12401.1 - 2.3e-05 25.0 0.0 0.00012 22.7 0.0 2.4 1 0 0 1 1 1 1 von Willebrand factor type A domain NTPase_1 PF03266.15 GAX12401.1 - 4.6e-05 23.4 2.4 6.2 6.7 0.0 5.1 5 0 0 5 5 4 0 NTPase Viral_helicase1 PF01443.18 GAX12401.1 - 5e-05 23.2 0.0 2.4 7.8 0.0 4.6 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase Roc PF08477.13 GAX12401.1 - 9.4e-05 22.6 1.0 7.4 6.8 0.0 5.3 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 GAX12401.1 - 0.0001 22.7 3.2 1.3 9.4 0.0 5.6 6 0 0 6 6 4 1 AAA domain IstB_IS21 PF01695.17 GAX12401.1 - 0.00017 21.3 0.2 8.3 6.1 0.0 4.7 5 0 0 5 5 4 0 IstB-like ATP binding protein cobW PF02492.19 GAX12401.1 - 0.00071 19.2 1.2 7.4 6.1 0.0 4.3 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 GAX12401.1 - 0.0013 18.2 0.0 2.9 7.3 0.0 4.4 5 0 0 5 5 5 1 Bacterial TniB protein RuvB_N PF05496.12 GAX12401.1 - 0.0018 18.0 1.8 1.4 8.6 0.1 5.0 5 1 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 GAX12401.1 - 0.002 17.9 1.0 1.7 8.4 0.1 4.5 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 GAX12401.1 - 0.0022 17.9 0.8 9.2 6.1 0.0 4.7 5 0 0 5 5 4 0 Deoxynucleoside kinase AAA_23 PF13476.6 GAX12401.1 - 0.0037 17.8 0.0 0.0037 17.8 0.0 8.5 6 1 0 7 7 5 2 AAA domain AAA_21 PF13304.6 GAX12401.1 - 0.0062 16.4 8.6 2.2 8.0 0.0 5.6 6 0 0 6 6 5 1 AAA domain, putative AbiEii toxin, Type IV TA system CbiA PF01656.23 GAX12401.1 - 0.012 15.7 0.7 25 5.0 0.0 4.4 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 GAX12401.1 - 0.016 15.0 0.6 22 4.7 0.0 3.9 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 GAX12401.1 - 0.031 13.8 0.6 44 3.6 0.0 4.5 5 0 0 5 5 4 0 Ferrous iron transport protein B CPT PF07931.12 GAX12401.1 - 0.038 13.8 3.0 88 2.9 0.0 5.3 6 0 0 6 6 6 0 Chloramphenicol phosphotransferase-like protein Glyco_hydro_79n PF03662.14 GAX12401.1 - 0.082 11.8 0.4 0.17 10.8 0.4 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain MobB PF03205.14 GAX12401.1 - 1.5 8.7 3.7 1.1e+02 2.6 0.1 4.4 5 0 0 5 5 4 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.15 GAX12401.1 - 7.3 6.6 13.5 1.9 8.5 0.0 5.0 6 0 0 6 6 4 0 Type III restriction enzyme, res subunit Thioredoxin_8 PF13905.6 GAX12402.1 - 1.4e-16 60.6 0.0 2.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 GAX12402.1 - 0.00012 21.9 0.1 0.00019 21.1 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 GAX12402.1 - 0.00015 21.5 0.0 0.00087 19.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX12402.1 - 0.00089 19.7 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 GAX12402.1 - 0.0011 19.0 0.0 0.0029 17.6 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 GAX12402.1 - 0.0021 17.9 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF953 PF06110.11 GAX12402.1 - 0.075 12.7 0.1 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Na_H_antiporter PF03553.14 GAX12403.1 - 6.1e-40 137.3 28.0 4.6e-28 98.3 14.2 3.1 2 1 1 3 3 3 3 Na+/H+ antiporter family TSP_1 PF00090.19 GAX12404.1 - 2.2 8.6 70.0 0.031 14.5 7.1 5.6 5 0 0 5 5 5 0 Thrombospondin type 1 domain DUF2039 PF10217.9 GAX12405.1 - 8.6e-26 90.1 9.0 8.6e-26 90.1 9.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2039) TackOD1 PF18551.1 GAX12405.1 - 0.0098 15.6 3.0 0.02 14.6 3.0 1.5 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 HypA PF01155.19 GAX12405.1 - 0.018 15.1 1.5 0.018 15.1 1.5 2.1 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MAS20 PF02064.15 GAX12405.1 - 0.051 13.7 1.3 0.16 12.0 1.3 1.8 1 0 0 1 1 1 0 MAS20 protein import receptor Zn_ribbon_SprT PF17283.2 GAX12405.1 - 0.2 11.6 0.2 0.2 11.6 0.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DZR PF12773.7 GAX12405.1 - 1.6 8.8 11.7 11 6.2 8.4 2.6 2 1 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 GAX12405.1 - 2 8.5 10.4 1 9.4 7.5 2.0 2 1 0 2 2 2 0 zinc-ribbons DUF2757 PF10955.8 GAX12405.1 - 2.2 8.6 8.9 4.9 7.5 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2757) FAM176 PF14851.6 GAX12405.1 - 2.3 7.8 6.3 1.1 8.9 2.6 2.1 2 0 0 2 2 2 0 FAM176 family zinc_ribbon_2 PF13240.6 GAX12405.1 - 4.3 7.2 7.9 8.5 6.2 3.4 2.7 2 0 0 2 2 2 0 zinc-ribbon domain PBP1_TM PF14812.6 GAX12405.1 - 7 7.1 15.9 0.32 11.4 8.0 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bestrophin PF01062.21 GAX12406.1 - 3.4e-22 79.2 1.2 5.2e-22 78.6 1.2 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RP854 PF17460.2 GAX12406.1 - 0.2 11.4 0.0 0.63 9.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein RP854 Mito_carr PF00153.27 GAX12407.1 - 5.8e-17 61.4 1.5 1.7e-06 27.8 0.0 4.1 4 0 0 4 4 4 3 Mitochondrial carrier protein F-box_4 PF15966.5 GAX12408.1 - 0.00077 19.3 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 GAX12408.1 - 0.0075 16.1 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAX12408.1 - 0.044 13.7 0.1 0.099 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box domain Rhodanese PF00581.20 GAX12409.1 - 0.00054 20.5 0.0 0.0013 19.2 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Pep_deformylase PF01327.21 GAX12410.1 - 1.1e-25 90.1 0.0 1.5e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase SelK_SelG PF10961.8 GAX12412.1 - 0.15 12.7 0.3 0.15 12.7 0.3 2.5 1 1 1 2 2 2 0 Selenoprotein SelK_SelG SASA PF03629.18 GAX12413.1 - 1.4e-26 93.6 0.0 2.1e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase HMG_box PF00505.19 GAX12414.1 - 2.3e-13 50.4 2.9 2.8e-08 34.0 0.8 3.2 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX12414.1 - 4.2e-08 33.7 0.4 4.1e-05 24.1 0.4 2.8 2 0 0 2 2 2 2 HMG-box domain OPA3 PF07047.12 GAX12416.1 - 2.9e-33 114.3 1.3 3.9e-33 113.9 0.7 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Prefoldin PF02996.17 GAX12416.1 - 0.014 15.3 0.9 0.023 14.6 0.9 1.4 1 0 0 1 1 1 0 Prefoldin subunit AAA_13 PF13166.6 GAX12416.1 - 0.035 12.8 1.8 0.057 12.1 1.7 1.3 2 0 0 2 2 2 0 AAA domain KLRAQ PF10205.9 GAX12416.1 - 0.045 14.0 4.2 0.082 13.2 4.2 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF724 PF05266.14 GAX12416.1 - 0.053 13.4 6.5 0.089 12.6 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF16 PF01519.16 GAX12416.1 - 0.19 12.3 3.2 0.37 11.3 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 PAXX PF15384.6 GAX12416.1 - 0.21 11.3 2.1 0.31 10.7 2.1 1.4 1 1 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DUF4140 PF13600.6 GAX12416.1 - 3.2 8.3 5.7 11 6.5 5.7 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Methyltransf_3 PF01596.17 GAX12418.1 - 4.7e-27 94.5 2.4 9.4e-19 67.4 2.6 3.5 3 1 0 3 3 3 2 O-methyltransferase UPF0176_N PF17773.1 GAX12418.1 - 3.1e-22 78.7 0.0 7.4e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAX12418.1 - 2.4e-14 53.4 7.7 4.6e-14 52.5 7.7 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 GAX12418.1 - 5.4e-07 30.1 0.0 9.3e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain Methyltransf_24 PF13578.6 GAX12418.1 - 3.5e-06 28.0 0.1 2.1e-05 25.5 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAX12418.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) YL1 PF05764.13 GAX12418.1 - 0.14 12.3 0.1 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Popeye PF04831.13 GAX12419.1 - 4.6e-07 30.1 0.0 9.2e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 GAX12419.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Redoxin PF08534.10 GAX12420.1 - 2.7e-25 88.8 0.0 3.3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAX12420.1 - 1.1e-10 41.4 0.0 1.4e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX12421.1 - 7.8e-24 84.1 0.0 1.8e-23 82.9 0.0 1.6 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 GAX12421.1 - 7.2e-07 29.2 0.0 9.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family GCV_H PF01597.19 GAX12422.1 - 0.00062 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein EFG_IV PF03764.18 GAX12423.1 - 2.2e-36 124.3 0.2 5.4e-36 123.0 0.1 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 GAX12423.1 - 4.3e-33 113.2 0.2 6.1e-32 109.5 0.1 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GAX12423.1 - 8.6e-13 48.5 0.3 1e-11 45.0 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAX12423.1 - 2e-08 34.1 0.0 6.4e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain GTP_EFTU PF00009.27 GAX12423.1 - 0.00019 21.0 0.1 0.0029 17.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX12423.1 - 0.0073 16.3 0.0 0.042 13.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus AvrPtoB_bdg PF16847.5 GAX12423.1 - 0.0089 16.5 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Avirulence AvrPtoB, BAK1-binding domain SBDS_C PF09377.10 GAX12423.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 SBDS protein C-terminal domain SASP PF00269.20 GAX12425.1 - 0.1 12.6 0.2 0.31 11.1 0.2 1.8 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type GTP_EFTU PF00009.27 GAX12426.1 - 9.6e-34 116.6 0.0 9.6e-34 116.6 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAX12426.1 - 1.5e-18 66.9 0.0 5.1e-18 65.1 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 GAX12426.1 - 7.8e-17 61.0 0.2 4e-16 58.7 0.2 2.4 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 GAX12426.1 - 3.5e-08 33.5 0.9 3e-07 30.5 0.2 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAX12426.1 - 1.8e-07 31.5 11.8 4.2e-06 27.1 0.2 5.0 4 0 0 4 4 4 2 Elongation factor Tu domain 2 Roc PF08477.13 GAX12426.1 - 2.1e-05 24.7 0.0 0.0001 22.5 0.0 2.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX12426.1 - 0.0046 16.6 0.0 0.023 14.3 0.0 2.3 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.18 GAX12426.1 - 0.0053 16.3 0.9 0.046 13.2 0.2 2.9 2 1 1 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX12426.1 - 0.0089 15.9 4.0 0.48 10.3 0.6 3.3 1 1 2 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 GAX12426.1 - 0.02 15.2 0.2 0.086 13.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 GAX12426.1 - 0.031 14.0 0.0 0.13 12.0 0.0 2.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mon2_C PF16206.5 GAX12426.1 - 0.18 9.9 0.0 0.29 9.2 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of Mon2 protein AAA_16 PF13191.6 GAX12426.1 - 0.72 10.2 0.0 0.72 10.2 0.0 3.4 1 1 2 3 3 2 0 AAA ATPase domain RPAP1_N PF08621.10 GAX12427.1 - 0.0043 16.8 9.8 0.22 11.3 0.2 2.6 2 0 0 2 2 2 2 RPAP1-like, N-terminal TetR_C_28 PF17937.1 GAX12427.1 - 0.017 15.5 2.4 0.38 11.2 1.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CitG PF01874.16 GAX12427.1 - 0.022 14.4 0.3 0.04 13.5 0.3 1.4 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase DUF4446 PF14584.6 GAX12427.1 - 1.4 8.9 4.3 2.5 8.1 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) T3SS_needle_F PF09392.10 GAX12427.1 - 2.8 8.2 6.2 4.5 7.5 3.6 2.8 2 1 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Rotamase_2 PF13145.6 GAX12427.1 - 3.8 8.4 8.2 0.53 11.1 2.2 2.2 1 1 0 2 2 2 0 PPIC-type PPIASE domain FKBP_N PF01346.18 GAX12427.1 - 4.7 8.3 12.4 5.5 8.0 5.8 2.7 2 1 1 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4199 PF13858.6 GAX12427.1 - 6 7.2 11.1 3.9 7.9 3.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) PAP_fibrillin PF04755.12 GAX12428.1 - 6.3e-17 62.2 0.0 5.9e-15 55.7 0.0 2.7 1 1 0 1 1 1 1 PAP_fibrillin tRNA_edit PF04073.15 GAX12430.1 - 5.3e-08 33.0 0.0 8e-07 29.2 0.0 2.2 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain FGGY_C PF02782.16 GAX12432.1 - 3.1e-20 72.7 0.1 5.2e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAX12432.1 - 9.5e-13 48.3 0.0 1.3e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FtsA PF14450.6 GAX12432.1 - 0.031 14.7 0.1 0.051 14.0 0.1 1.6 1 1 0 1 1 1 0 Cell division protein FtsA Sigma70_r2 PF04542.14 GAX12434.1 - 1.3e-11 44.1 0.0 3.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GAX12434.1 - 1.6e-08 33.9 2.8 5.2e-08 32.3 0.3 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 GAX12434.1 - 0.00075 19.6 0.3 0.12 12.5 0.1 3.6 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 GAX12434.1 - 0.0069 16.4 1.0 0.016 15.2 0.3 2.0 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 HTH_Crp_2 PF13545.6 GAX12434.1 - 0.0072 16.3 2.7 2.4 8.2 0.1 3.6 4 0 0 4 4 4 2 Crp-like helix-turn-helix domain HTH_15 PF12324.8 GAX12434.1 - 0.033 14.2 0.1 23 5.0 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase Peptidase_S9 PF00326.21 GAX12435.1 - 2.2e-42 145.0 0.0 3.1e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAX12435.1 - 4.8e-08 32.8 0.0 7.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAX12435.1 - 1.4e-05 24.5 0.0 0.00014 21.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 GAX12435.1 - 0.0029 17.7 0.0 0.037 14.1 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 GAX12435.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PhoPQ_related PF10142.9 GAX12435.1 - 0.13 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein T2SSF PF00482.23 GAX12437.1 - 0.088 12.8 0.6 6.3 6.8 0.2 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F U-box PF04564.15 GAX12439.1 - 9.6e-14 51.3 0.5 3.5e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 GAX12439.1 - 2.3e-08 33.7 0.4 2.3e-08 33.7 0.4 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 GAX12439.1 - 1.6e-05 24.9 0.1 6.1e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX12439.1 - 3.1e-05 23.7 0.3 6.9e-05 22.6 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX12439.1 - 0.0013 19.1 0.3 0.0013 19.1 0.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 GAX12439.1 - 0.0071 16.6 0.1 0.017 15.4 0.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX12439.1 - 0.096 12.6 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GUCT PF08152.12 GAX12439.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 GUCT (NUC152) domain Myb_DNA-binding PF00249.31 GAX12440.1 - 3.4e-15 56.0 0.3 5.8e-15 55.2 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX12440.1 - 3.1e-05 24.1 0.1 5.8e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX12440.1 - 9e-05 22.3 0.1 0.00015 21.6 0.1 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Kinesin PF00225.23 GAX12441.1 - 2.5e-60 204.1 1.1 6.1e-60 202.9 1.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX12441.1 - 1.3e-31 109.6 0.1 3.8e-31 108.0 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding NAD_binding_6 PF08030.12 GAX12442.1 - 0.017 15.2 0.7 0.032 14.4 0.7 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Cadherin_C_2 PF16492.5 GAX12442.1 - 0.15 12.8 4.6 0.53 11.1 0.0 3.4 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal Na_H_antiport_2 PF13726.6 GAX12442.1 - 9.7 6.4 8.2 0.6 10.3 2.0 2.1 2 0 0 2 2 2 0 Na+-H+ antiporter family COX6A PF02046.15 GAX12443.1 - 4.7e-06 27.1 0.1 1.3e-05 25.7 0.1 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa Clathrin_lg_ch PF01086.17 GAX12444.1 - 4.5e-26 92.3 6.6 5.1e-26 92.2 6.6 1.1 1 0 0 1 1 1 1 Clathrin light chain AAA PF00004.29 GAX12445.1 - 3.2e-88 292.9 0.0 2.6e-45 154.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX12445.1 - 1.3e-25 88.9 5.7 5e-12 45.4 0.1 3.5 3 0 0 3 3 3 2 AAA+ lid domain AAA_2 PF07724.14 GAX12445.1 - 2.1e-14 54.0 0.0 1.1e-08 35.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX12445.1 - 1.4e-13 51.0 0.0 1.4e-07 31.6 0.0 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX12445.1 - 1.6e-12 47.5 0.0 2.3e-05 24.2 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX12445.1 - 1.7e-12 48.1 0.0 5.5e-05 23.6 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain CDC48_N PF02359.18 GAX12445.1 - 6.2e-11 42.3 0.1 3.9e-10 39.8 0.1 2.4 2 1 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.13 GAX12445.1 - 2.2e-10 40.3 0.0 6.9e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 GAX12445.1 - 2.6e-10 40.6 0.0 0.00065 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX12445.1 - 5e-08 33.3 1.6 0.22 11.8 0.0 4.1 2 2 2 4 4 4 2 AAA domain AAA_18 PF13238.6 GAX12445.1 - 5.4e-08 33.4 0.0 0.012 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAX12445.1 - 3e-07 30.5 0.0 0.0073 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 GAX12445.1 - 3.7e-07 30.7 0.1 0.0087 16.6 0.0 3.1 2 1 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 GAX12445.1 - 7.5e-07 29.0 0.0 0.003 17.3 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 GAX12445.1 - 1.2e-06 28.8 0.0 0.012 16.0 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Viral_helicase1 PF01443.18 GAX12445.1 - 4.3e-06 26.6 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 GAX12445.1 - 4.8e-06 26.1 0.1 0.01 15.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAX12445.1 - 5.5e-06 26.2 0.1 0.089 12.5 0.1 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 GAX12445.1 - 9e-06 26.0 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 GAX12445.1 - 1.1e-05 25.5 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC48_2 PF02933.17 GAX12445.1 - 1.1e-05 25.1 0.0 3.8e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 GAX12445.1 - 1.4e-05 24.6 0.2 0.035 13.4 0.1 3.0 2 1 0 2 2 2 1 KaiC NACHT PF05729.12 GAX12445.1 - 1.6e-05 24.9 0.5 0.51 10.3 0.0 3.5 3 1 0 3 3 3 2 NACHT domain AAA_7 PF12775.7 GAX12445.1 - 2.5e-05 23.9 0.1 0.24 10.9 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 GAX12445.1 - 2.7e-05 24.2 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_17 PF13207.6 GAX12445.1 - 4.4e-05 23.9 0.0 0.091 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX12445.1 - 6.5e-05 22.6 3.0 1.1 8.8 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 GAX12445.1 - 8.8e-05 22.3 0.0 0.32 10.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 GAX12445.1 - 0.0001 22.3 4.2 0.38 10.6 0.0 3.7 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 GAX12445.1 - 0.00027 20.3 0.1 0.73 9.1 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 GAX12445.1 - 0.00039 20.1 0.1 0.046 13.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain PhoH PF02562.16 GAX12445.1 - 0.00061 19.3 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.18 GAX12445.1 - 0.00067 19.6 0.0 2.4 8.0 0.0 3.2 3 1 0 3 3 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 GAX12445.1 - 0.00072 18.7 0.2 0.042 12.9 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Vps4_C PF09336.10 GAX12445.1 - 0.00081 19.3 0.0 0.0082 16.1 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 GAX12445.1 - 0.00083 18.6 0.0 0.78 8.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.6 GAX12445.1 - 0.0011 19.1 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 GAX12445.1 - 0.0014 18.8 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 GAX12445.1 - 0.0019 17.4 0.0 0.42 9.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Cytidylate_kin PF02224.18 GAX12445.1 - 0.003 17.3 0.2 0.46 10.2 0.1 2.5 2 0 0 2 2 2 1 Cytidylate kinase PduV-EutP PF10662.9 GAX12445.1 - 0.0047 16.7 0.1 4 7.2 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_3 PF07726.11 GAX12445.1 - 0.0056 16.5 0.0 2.1 8.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GAX12445.1 - 0.0069 16.9 1.4 4.2 7.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 GAX12445.1 - 0.0078 16.1 0.9 3.1 7.7 0.1 3.4 2 1 1 3 3 3 0 NTPase SKI PF01202.22 GAX12445.1 - 0.014 15.5 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Molydop_binding PF01568.21 GAX12445.1 - 0.014 15.4 0.7 0.6 10.1 0.0 3.0 2 1 1 3 3 2 0 Molydopterin dinucleotide binding domain AAA_30 PF13604.6 GAX12445.1 - 0.018 14.8 0.2 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF1967 PF09269.11 GAX12445.1 - 0.026 14.4 0.0 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) IPT PF01745.16 GAX12445.1 - 0.035 13.5 0.4 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase T2SSE PF00437.20 GAX12445.1 - 0.043 12.9 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 GAX12445.1 - 0.059 13.4 0.0 5.7 6.9 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_6 PF12774.7 GAX12445.1 - 0.063 12.2 0.3 0.53 9.2 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CPT PF07931.12 GAX12445.1 - 0.077 12.8 0.0 3.7 7.3 0.0 2.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 GAX12445.1 - 0.089 12.7 0.0 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF5305 PF17231.2 GAX12445.1 - 0.092 12.1 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 1 0 Family of unknown function (DUF5305) AAA_19 PF13245.6 GAX12445.1 - 0.12 12.7 2.2 20 5.5 0.0 3.0 2 1 1 3 3 2 0 AAA domain DUF2075 PF09848.9 GAX12445.1 - 0.76 8.9 2.4 9.4 5.4 0.0 2.6 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 GAX12447.1 - 2e-42 144.9 1.6 7e-42 143.2 0.0 2.7 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12447.1 - 2.4e-30 105.2 0.0 8.2e-30 103.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 GAX12447.1 - 0.015 15.4 0.8 0.029 14.5 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle ResIII PF04851.15 GAX12447.1 - 0.016 15.2 0.1 0.097 12.7 0.0 2.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX12447.1 - 0.046 12.9 0.2 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 GAX12447.1 - 0.076 12.3 0.3 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain zf-CCHC_4 PF14392.6 GAX12447.1 - 0.81 9.5 3.4 1.3 8.8 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle SPRY PF00622.28 GAX12448.1 - 2.7e-05 24.3 0.1 0.00057 20.0 0.1 2.2 1 1 0 1 1 1 1 SPRY domain DarA_N PF18788.1 GAX12448.1 - 0.07 13.2 0.0 3.1 7.9 0.1 2.4 1 1 1 2 2 2 0 Defence against restriction A N-terminal Thioredoxin_3 PF13192.6 GAX12448.1 - 0.3 11.2 1.4 0.69 10.0 1.4 1.6 1 1 0 1 1 1 0 Thioredoxin domain Sulfotransfer_2 PF03567.14 GAX12450.1 - 6e-08 32.9 0.1 1.1e-07 32.1 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAX12450.1 - 0.0012 17.8 2.9 0.019 13.9 1.3 3.1 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Ricin_B_lectin PF00652.22 GAX12451.1 - 0.00016 22.0 2.2 0.0083 16.4 0.5 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain PAN_4 PF14295.6 GAX12451.1 - 0.0014 18.5 18.7 1 9.3 0.9 4.6 4 0 0 4 4 4 4 PAN domain CDtoxinA PF03498.14 GAX12451.1 - 0.0042 16.7 0.8 0.044 13.4 0.2 1.6 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain WAP PF00095.21 GAX12451.1 - 2.4 8.6 33.3 2.3 8.7 1.7 5.0 5 0 0 5 5 5 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' ThiF PF00899.21 GAX12455.1 - 4.9e-62 209.5 0.0 9.1e-62 208.6 0.0 1.4 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 GAX12455.1 - 7.6e-12 45.7 0.1 2.4e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 GAX12455.1 - 4e-08 33.5 1.2 1.5e-05 25.0 0.9 2.3 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 GAX12455.1 - 0.00044 20.7 0.3 0.0015 18.9 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 GAX12455.1 - 0.023 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX12455.1 - 0.031 14.5 0.9 0.21 11.8 0.9 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 GAX12455.1 - 0.079 13.5 0.3 0.33 11.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1644 PF07800.12 GAX12457.1 - 3.4 7.7 16.0 2.5 8.1 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) TEX19 PF15553.6 GAX12457.1 - 4.3 7.3 8.7 0.21 11.6 2.3 1.9 2 1 0 2 2 2 0 Testis-expressed protein 19 DUF179 PF02622.15 GAX12459.1 - 5.2e-11 42.8 0.0 9.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 GST_C_2 PF13410.6 GAX12462.1 - 0.037 14.0 0.1 2 8.5 0.0 2.4 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Peptidase_S9 PF00326.21 GAX12462.1 - 0.051 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family tRNA_Me_trans PF03054.16 GAX12463.1 - 2.1e-110 368.8 0.0 2.8e-110 368.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase SufE PF02657.15 GAX12463.1 - 4e-14 52.5 0.2 7.3e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 Fe-S metabolism associated domain ThiI PF02568.14 GAX12463.1 - 0.0016 18.0 0.1 0.0088 15.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 GAX12463.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase NAD_synthase PF02540.17 GAX12463.1 - 0.01 15.0 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 GAX12463.1 - 0.013 15.0 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 GAX12463.1 - 0.04 13.7 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 PP-loop family dsDNA_bind PF01984.20 GAX12465.1 - 1.2e-19 70.6 7.2 1.5e-19 70.3 7.2 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Tristanin_u2 PF16638.5 GAX12465.1 - 0.054 14.3 1.2 0.054 14.3 1.2 1.6 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Reprolysin_5 PF13688.6 GAX12466.1 - 0.00035 20.8 0.1 0.0031 17.7 0.0 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX12466.1 - 0.004 17.7 0.1 0.0094 16.5 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 GAX12466.1 - 0.0043 15.7 0.0 0.0052 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M66 PF10462.9 GAX12466.1 - 0.015 14.3 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 GAX12466.1 - 0.026 14.4 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 GAX12466.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ATP-grasp_6 PF18419.1 GAX12466.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp-like domain Reprolysin_4 PF13583.6 GAX12466.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 GAX12466.1 - 0.21 11.2 0.1 0.61 9.7 0.0 1.7 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Na_H_Exchanger PF00999.21 GAX12467.1 - 3.9e-40 137.8 33.3 5.3e-40 137.4 33.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peptidase_M10_C PF08548.11 GAX12467.1 - 0.091 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal OppC_N PF12911.7 GAX12467.1 - 5.3 7.1 5.9 20 5.2 0.1 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Na_H_Exchanger PF00999.21 GAX12468.1 - 1.9e-41 142.1 37.6 2.5e-41 141.8 37.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Reprolysin_3 PF13582.6 GAX12469.1 - 0.0019 18.7 0.2 0.0048 17.4 0.3 1.6 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX12469.1 - 0.0079 16.1 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 GAX12469.1 - 0.016 15.3 1.0 0.1 12.7 1.0 1.9 1 1 1 2 2 2 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 GAX12469.1 - 0.047 13.6 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX12470.1 - 0.0012 19.3 0.0 0.0018 18.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX12470.1 - 0.0041 17.3 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 GAX12470.1 - 0.024 13.6 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 GAX12470.1 - 0.029 14.3 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M78 PF06114.13 GAX12470.1 - 0.07 13.1 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 IrrE N-terminal-like domain Metallopep PF12044.8 GAX12470.1 - 0.075 11.6 0.1 0.098 11.2 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.24 GAX12470.1 - 0.083 12.7 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 GAX12471.1 - 5e-05 23.5 0.0 8.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX12471.1 - 0.0017 18.8 0.0 0.0049 17.4 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX12471.1 - 0.0038 17.1 0.3 0.0088 16.0 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 GAX12471.1 - 0.016 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 GAX12471.1 - 0.021 14.5 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 GAX12471.1 - 0.04 12.5 0.5 0.066 11.8 0.5 1.3 1 0 0 1 1 1 0 Putative peptidase family AWS PF17907.1 GAX12471.1 - 8.1 6.6 6.9 0.92 9.6 1.7 2.1 2 0 0 2 2 2 0 AWS domain Amino_oxidase PF01593.24 GAX12472.1 - 1.8e-39 136.3 0.9 6.6e-27 94.9 0.4 2.6 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase PAP2 PF01569.21 GAX12472.1 - 2.5e-25 88.8 2.9 1.6e-24 86.2 0.6 2.3 1 1 1 2 2 2 1 PAP2 superfamily HA PF03457.14 GAX12472.1 - 5e-24 84.4 8.8 7.2e-14 51.9 0.5 3.3 3 0 0 3 3 3 2 Helicase associated domain NAD_binding_8 PF13450.6 GAX12472.1 - 1.9e-13 50.4 0.0 5.7e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX12472.1 - 1.2e-07 31.7 1.6 1.9e-05 24.4 0.1 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX12472.1 - 9.6e-06 24.5 0.2 0.016 13.9 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 GAX12472.1 - 1.7e-05 24.2 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 GAX12472.1 - 3.8e-05 23.7 5.6 0.0002 21.4 2.0 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAX12472.1 - 0.00064 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 GAX12472.1 - 0.00079 18.3 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 GAX12472.1 - 0.011 15.0 0.1 0.027 13.7 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX12472.1 - 0.025 13.6 0.1 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAX12472.1 - 0.04 13.0 0.1 0.3 10.1 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAX12472.1 - 0.045 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 GAX12472.1 - 0.053 12.9 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase PAP2_C PF14360.6 GAX12472.1 - 0.084 13.4 0.2 0.23 12.0 0.2 1.7 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Pyr_redox_3 PF13738.6 GAX12472.1 - 0.17 11.1 0.1 9.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAP2_3 PF14378.6 GAX12472.1 - 0.58 9.8 6.2 0.18 11.5 0.9 2.4 2 0 0 2 2 2 0 PAP2 superfamily MASE3 PF17159.4 GAX12473.1 - 0.14 11.8 2.3 0.26 10.9 2.3 1.4 1 1 0 1 1 1 0 Membrane-associated sensor domain Sulfotransfer_1 PF00685.27 GAX12474.1 - 1.1e-08 34.9 2.4 6.3e-08 32.4 2.4 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX12474.1 - 0.00014 22.3 1.1 0.038 14.4 0.1 2.6 1 1 1 2 2 2 2 Sulfotransferase family Nop14 PF04147.12 GAX12474.1 - 0.0098 14.2 23.9 0.013 13.8 23.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GAX12474.1 - 0.012 15.1 26.0 0.016 14.7 26.0 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GAX12474.1 - 0.083 12.0 26.4 0.13 11.4 26.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 GAX12474.1 - 0.12 10.7 20.5 0.18 10.1 20.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Adipogenin PF15202.6 GAX12474.1 - 0.38 10.8 0.0 0.38 10.8 0.0 2.4 2 1 0 2 2 1 0 Adipogenin SID-1_RNA_chan PF13965.6 GAX12474.1 - 0.41 9.0 1.3 0.59 8.5 1.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 GAX12474.1 - 0.79 7.6 3.6 1.1 7.1 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 GAX12474.1 - 1.4 8.0 8.1 1.9 7.6 8.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PTPRCAP PF15713.5 GAX12474.1 - 3.6 7.9 23.3 7.5 6.8 23.3 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4834 PF16118.5 GAX12474.1 - 7.2 7.6 9.3 72 4.4 9.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Cauli_VI PF01693.16 GAX12475.1 - 1.5e-19 70.0 2.9 2.7e-19 69.2 2.9 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 GAX12475.1 - 2e-11 43.8 1.9 1e-09 38.2 1.9 3.1 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 GAX12475.1 - 0.00011 22.4 0.7 0.00035 20.8 0.7 1.8 1 1 0 1 1 1 1 RNase H Qua1 PF16274.5 GAX12475.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 Qua1 domain Arrestin_N PF00339.29 GAX12476.1 - 2.8e-09 37.2 0.2 0.021 14.9 0.0 4.1 4 0 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAX12476.1 - 8.4e-05 23.0 0.6 8.4e-05 23.0 0.6 2.5 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain adh_short PF00106.25 GAX12477.1 - 4e-26 91.7 0.0 5.5e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX12477.1 - 2.7e-16 59.9 0.0 3.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX12477.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAX12477.1 - 0.0013 18.1 0.1 0.0028 17.1 0.1 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAX12477.1 - 0.068 13.1 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding Glyco_transf_15 PF01793.16 GAX12478.1 - 7.8e-19 68.1 12.6 3e-18 66.2 12.6 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Rieske PF00355.26 GAX12479.1 - 1.8e-18 66.2 0.1 3.5e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GAX12479.1 - 9.7e-10 38.5 0.0 4.6e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Pheophorbide a oxygenase Chloroa_b-bind PF00504.21 GAX12480.1 - 7.7e-39 133.8 0.0 1e-38 133.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX12481.1 - 7.3e-41 140.4 0.1 1e-40 139.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DctP PF03480.13 GAX12481.1 - 0.0033 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Fea1 PF07692.11 GAX12483.1 - 2.7e-13 49.7 33.7 8.9e-05 21.7 2.4 7.1 6 2 0 6 6 6 6 Low iron-inducible periplasmic protein FA_desaturase PF00487.24 GAX12484.1 - 2.7e-23 83.1 27.3 4.9e-23 82.3 27.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 GAX12484.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Tyr-DNA_phospho PF06087.12 GAX12486.1 - 6.8e-69 232.8 0.0 8e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Synaphin PF05835.12 GAX12487.1 - 0.17 12.1 6.6 0.29 11.4 6.6 1.3 1 0 0 1 1 1 0 Synaphin protein fragilysinNterm PF16376.5 GAX12489.1 - 0.0049 16.6 0.0 0.3 10.8 0.0 3.5 5 0 0 5 5 5 1 N-terminal domain of fragilysin CTD PF12815.7 GAX12489.1 - 0.062 13.9 0.8 54 4.5 0.0 3.6 4 0 0 4 4 4 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DDE_Tnp_4 PF13359.6 GAX12490.1 - 3.5e-29 101.5 0.0 6.4e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAX12490.1 - 1e-08 35.1 0.4 1.1e-07 31.7 0.4 2.2 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 GAX12490.1 - 0.00024 20.8 0.1 0.00062 19.4 0.1 1.6 1 1 0 1 1 1 1 Plant transposon protein FliT PF05400.13 GAX12491.1 - 0.063 14.1 1.3 0.2 12.5 1.3 1.9 1 0 0 1 1 1 0 Flagellar protein FliT DUF2852 PF11014.8 GAX12491.1 - 0.25 11.5 4.0 0.13 12.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) ING PF12998.7 GAX12491.1 - 0.51 11.0 8.4 1.1 9.9 0.0 3.0 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Virulence_fact PF13769.6 GAX12491.1 - 0.84 9.9 6.8 18 5.6 3.0 3.1 3 0 0 3 3 3 0 Virulence factor CDH1_2_SANT_HL1 PF18375.1 GAX12491.1 - 0.86 10.3 7.3 0.26 12.0 2.5 2.4 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 BTB PF00651.31 GAX12492.1 - 4.2e-13 49.5 0.9 9.3e-13 48.4 0.4 1.8 1 1 1 2 2 2 1 BTB/POZ domain DUF3342 PF11822.8 GAX12492.1 - 0.0026 17.9 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 GAX12493.1 - 3.6e-15 56.2 0.3 6.7e-15 55.3 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAX12494.1 - 9.2e-10 38.7 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAX12495.1 - 1.2e-11 44.8 0.1 1.2e-11 44.8 0.1 2.0 3 0 0 3 3 3 1 BTB/POZ domain BTB PF00651.31 GAX12497.1 - 2.5e-08 34.1 0.0 5.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAX12498.1 - 7.9e-16 58.3 0.2 3e-15 56.4 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Cytochrome_CBB3 PF13442.6 GAX12499.1 - 2.9e-18 65.9 0.2 4.3e-18 65.4 0.2 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAX12499.1 - 1.4e-09 37.8 0.1 2.4e-07 30.5 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c-550 domain Cytochrom_C PF00034.21 GAX12499.1 - 4.3e-09 37.4 0.7 1.3e-08 35.8 0.7 1.8 1 1 0 1 1 1 1 Cytochrome c 2OG-FeII_Oxy_3 PF13640.6 GAX12500.1 - 7e-06 26.9 0.0 1.3e-05 26.0 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily aGPT-Pplase1 PF18723.1 GAX12501.1 - 4.9e-41 141.0 3.4 4.2e-39 134.7 3.4 2.1 1 1 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Tudor_4 PF18358.1 GAX12501.1 - 0.03 13.9 0.0 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain Dynein_C PF18199.1 GAX12501.1 - 0.13 11.5 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain PHD PF00628.29 GAX12501.1 - 0.45 10.4 14.9 0.44 10.5 12.9 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING_5 PF14634.6 GAX12501.1 - 6.4 6.8 16.2 1.1 9.3 11.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Helicase_C PF00271.31 GAX12502.1 - 4.9e-15 55.8 0.0 1.1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX12502.1 - 3.1e-06 27.1 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 GAX12502.1 - 0.00013 22.2 0.2 0.0005 20.3 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) XPG_I_2 PF12813.7 GAX12502.1 - 0.042 13.3 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing SAD_SRA PF02182.17 GAX12502.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 SAD/SRA domain PC-Esterase PF13839.6 GAX12505.1 - 1.5e-05 24.9 0.1 0.0024 17.7 0.1 2.2 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Eno-Rase_NADH_b PF12242.8 GAX12505.1 - 0.11 12.3 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pirin PF02678.16 GAX12506.1 - 8.2e-30 103.0 0.3 1.3e-29 102.3 0.3 1.3 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 GAX12506.1 - 4.7e-15 55.5 0.0 9.2e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 GAX12506.1 - 3.6e-07 29.8 0.4 1.2e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Cupin domain Pirin_C PF05726.13 GAX12506.1 - 0.0042 17.4 0.0 0.062 13.7 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain S4 PF01479.25 GAX12506.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 S4 domain Amino_oxidase PF01593.24 GAX12507.1 - 3.7e-44 151.8 0.0 2.2e-43 149.2 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX12507.1 - 4.9e-09 36.3 0.5 1.3e-08 34.9 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAX12507.1 - 0.00014 21.9 0.1 0.0019 18.2 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 GAX12507.1 - 0.0014 18.3 0.0 0.0035 17.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX12507.1 - 0.0049 16.2 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAX12507.1 - 0.019 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 GAX12507.1 - 0.037 12.8 0.0 0.074 11.7 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 GAX12507.1 - 0.037 14.6 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX12507.1 - 0.081 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 GAX12507.1 - 0.22 10.7 0.1 0.35 10.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Annexin PF00191.20 GAX12508.1 - 2e-44 149.5 3.1 3.6e-12 46.2 0.0 4.2 4 0 0 4 4 4 4 Annexin Mob_Pre PF01076.19 GAX12508.1 - 0.021 14.7 0.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Plasmid recombination enzyme Lipase_GDSL_2 PF13472.6 GAX12509.1 - 6.6e-15 56.0 0.0 1.4e-14 54.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX12509.1 - 8.6e-07 29.1 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Argos PF11581.8 GAX12509.1 - 0.052 13.6 0.1 0.095 12.7 0.1 1.3 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos UPF0054 PF02130.17 GAX12510.1 - 6e-28 97.2 1.4 4.1e-27 94.5 1.4 2.0 1 1 0 1 1 1 1 Uncharacterized protein family UPF0054 SPT2 PF08243.11 GAX12510.1 - 0.081 13.5 6.7 0.14 12.7 6.7 1.3 1 0 0 1 1 1 0 SPT2 chromatin protein Pkinase_Tyr PF07714.17 GAX12511.1 - 6.6e-29 101.0 0.0 3.4e-28 98.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX12511.1 - 1e-26 93.9 0.0 5.7e-26 91.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX12511.1 - 0.00016 20.6 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 GAX12512.1 - 5.4e-34 117.6 0.0 1.2e-33 116.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX12512.1 - 1.8e-30 106.2 0.0 2.8e-30 105.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX12512.1 - 0.00044 19.2 0.0 0.00094 18.1 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAX12512.1 - 0.098 12.2 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 GAX12512.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family CXCR4_N PF12109.8 GAX12512.1 - 0.11 12.8 0.3 0.37 11.0 0.3 1.9 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal DAO PF01266.24 GAX12513.1 - 2.3e-30 106.4 0.0 2.7e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 GAX12513.1 - 0.0028 17.1 0.8 0.013 14.9 1.2 1.7 2 0 0 2 2 2 1 ThiF family Ank_2 PF12796.7 GAX12514.1 - 2.8e-14 53.5 0.0 9.9e-06 26.1 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAX12514.1 - 2.6e-09 37.1 6.3 0.2 12.2 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 GAX12514.1 - 8.6e-07 28.8 4.8 1.4 9.7 0.0 7.9 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 GAX12514.1 - 1.4e-06 28.5 0.2 0.14 12.5 0.0 6.1 5 1 2 7 7 7 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX12514.1 - 6.2e-05 23.5 0.2 3.5 8.3 0.0 5.5 4 2 3 7 7 7 3 Ankyrin repeats (many copies) TPR_1 PF00515.28 GAX12515.1 - 4.8e-43 143.3 41.1 3.2e-06 26.7 0.8 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAX12515.1 - 1.4e-38 127.8 36.1 9.5e-06 25.4 0.3 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 GAX12515.1 - 4.9e-31 106.1 28.7 1.3e-09 37.5 0.2 9.3 5 3 4 9 9 9 6 TPR repeat STI1 PF17830.1 GAX12515.1 - 2.2e-29 101.1 19.8 1.6e-14 53.5 9.1 3.0 3 0 0 3 3 2 2 STI1 domain TPR_14 PF13428.6 GAX12515.1 - 8.2e-24 82.3 18.4 0.015 16.1 0.7 9.0 5 3 4 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAX12515.1 - 1.4e-23 81.0 32.4 0.002 18.2 2.3 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAX12515.1 - 1.6e-21 76.6 21.4 2.4e-05 24.9 2.2 6.6 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAX12515.1 - 1.3e-17 64.0 23.7 0.00029 21.3 2.2 6.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAX12515.1 - 5.2e-16 58.7 25.0 3.7e-06 27.1 0.9 6.4 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAX12515.1 - 1e-15 56.9 21.2 0.00014 22.0 0.1 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAX12515.1 - 5.9e-11 42.4 6.0 0.02 15.0 0.1 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX12515.1 - 1.4e-09 37.3 14.8 0.39 10.8 0.3 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat XPC-binding PF09280.11 GAX12515.1 - 0.00043 19.9 10.3 0.013 15.2 1.5 2.5 2 0 0 2 2 2 2 XPC-binding domain ANAPC3 PF12895.7 GAX12515.1 - 0.0008 19.6 23.8 0.044 14.0 1.1 5.6 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAX12515.1 - 0.00089 19.1 31.7 0.039 13.9 1.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX12515.1 - 0.085 12.9 8.0 21 5.3 0.0 5.3 6 1 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat DUF357 PF04010.13 GAX12515.1 - 0.18 11.9 6.7 0.14 12.3 0.3 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF357) SHNi-TPR PF10516.9 GAX12515.1 - 0.2 11.2 7.8 0.82 9.2 0.0 4.2 4 0 0 4 4 4 0 SHNi-TPR TPR_6 PF13174.6 GAX12515.1 - 0.28 11.9 25.0 1.3 9.8 0.4 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAX12515.1 - 0.59 10.5 23.0 0.088 13.2 0.6 5.2 3 3 2 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAX12515.1 - 0.88 9.6 18.0 0.99 9.5 0.3 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAX12515.1 - 3 8.3 15.9 11 6.5 1.8 3.9 1 1 3 4 4 4 0 Alkyl sulfatase dimerisation MIT PF04212.18 GAX12515.1 - 3.8 7.6 31.0 28 4.9 0.0 8.0 5 1 3 8 8 8 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 GAX12515.1 - 6.7 7.1 23.3 19 5.7 0.1 5.6 4 1 2 6 6 6 0 Bacterial transcriptional activator domain Xpo1 PF08389.12 GAX12516.1 - 2.2e-06 27.8 7.5 7.4e-06 26.1 0.9 4.6 3 3 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 GAX12516.1 - 5.8e-05 22.9 0.1 0.00017 21.5 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.11 GAX12516.1 - 0.0092 15.2 0.7 0.018 14.2 0.2 1.8 2 0 0 2 2 2 1 CRM1 C terminal CRM1_repeat PF18777.1 GAX12516.1 - 0.081 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat HEAT_2 PF13646.6 GAX12516.1 - 0.14 12.6 1.3 14 6.1 0.0 4.2 4 1 0 4 4 4 0 HEAT repeats UAA PF08449.11 GAX12517.1 - 1.4e-40 139.4 12.7 2.3e-40 138.7 12.7 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX12517.1 - 6.3e-08 32.9 26.1 1.1e-05 25.6 13.8 2.8 2 1 1 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 GAX12517.1 - 0.0016 17.4 2.6 0.0016 17.4 2.6 2.3 1 1 2 3 3 3 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 GAX12517.1 - 0.0045 16.4 9.3 0.17 11.2 0.6 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family DAGAT PF03982.13 GAX12518.1 - 6.7e-15 54.8 0.0 9.3e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase AIM24 PF01987.17 GAX12519.1 - 4.2e-60 203.0 0.5 5.4e-60 202.6 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 dCMP_cyt_deam_1 PF00383.23 GAX12520.1 - 4.1e-05 23.4 0.0 7.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Dala_Dala_lig_C PF07478.13 GAX12521.1 - 7e-16 58.4 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 GAX12521.1 - 5.8e-13 49.6 0.0 1.9e-11 44.6 0.0 2.4 1 1 0 1 1 1 1 SET domain LacAB_rpiB PF02502.18 GAX12521.1 - 0.069 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase CCDC106 PF15794.5 GAX12522.1 - 0.0018 18.0 6.7 0.0018 18.0 6.7 2.2 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 106 Alpha-2-MRAP_C PF06401.11 GAX12522.1 - 0.81 9.6 9.4 0.39 10.7 5.0 2.4 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain GAS PF13851.6 GAX12522.1 - 1.4 8.2 18.8 0.55 9.5 9.8 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 GAX12522.1 - 2.3 8.1 6.5 2.4 8.0 3.4 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 GAX12522.1 - 3.7 7.6 11.6 1.8 8.6 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 GAX12522.1 - 5.7 7.0 21.8 0.41 10.7 7.0 3.7 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ndc1_Nup PF09531.10 GAX12522.1 - 6.6 5.3 16.8 0.62 8.7 7.2 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup VPS11_C PF12451.8 GAX12523.1 - 0.00013 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Pkinase PF00069.25 GAX12524.1 - 1.9e-76 256.9 0.0 2.7e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12524.1 - 5.3e-41 140.6 0.0 8.6e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 GAX12524.1 - 1.1e-09 38.7 1.7 4e-07 30.5 0.0 3.0 2 1 1 3 3 3 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 GAX12524.1 - 2.2e-09 37.1 0.0 4e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like KA1 PF02149.19 GAX12524.1 - 8.8e-08 31.8 0.0 2.9e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 GAX12524.1 - 0.0046 15.9 0.2 0.0072 15.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 GAX12524.1 - 0.092 11.6 0.1 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Adaptin_N PF01602.20 GAX12525.1 - 2.3e-98 330.0 0.6 3.5e-98 329.4 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAX12525.1 - 3.6e-17 62.9 2.2 4.9e-15 55.9 0.1 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX12525.1 - 2.3e-07 30.5 3.9 0.35 11.2 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 GAX12525.1 - 3e-05 24.3 1.7 2.3 8.6 0.0 4.7 4 1 2 6 6 6 4 HEAT repeats RTP1_C1 PF10363.9 GAX12525.1 - 0.00018 21.6 0.2 1 9.6 0.0 3.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 GAX12525.1 - 0.008 16.6 0.3 6.6 7.2 0.0 2.9 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cohesin_HEAT PF12765.7 GAX12525.1 - 0.017 15.4 0.2 0.39 11.1 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion IMUP PF15761.5 GAX12525.1 - 1.5 9.6 14.2 2.3 9.0 5.8 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Cyclin_N PF00134.23 GAX12526.1 - 8.8e-19 67.5 0.0 1.8e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX12526.1 - 1.5e-07 31.5 0.4 8.8e-07 29.0 0.0 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain Amino_oxidase PF01593.24 GAX12527.1 - 1.3e-12 47.8 0.0 2.5e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX12527.1 - 1.4e-12 47.6 0.0 4.3e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX12527.1 - 7.5e-09 35.2 1.2 5.7e-05 22.4 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX12527.1 - 6.7e-07 29.2 0.2 0.0054 16.4 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase GDI PF00996.18 GAX12527.1 - 1.6e-06 26.9 0.2 0.0032 16.1 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Pyr_redox_2 PF07992.14 GAX12527.1 - 1.5e-05 24.4 0.8 0.0049 16.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX12527.1 - 0.00013 21.2 1.4 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 GAX12527.1 - 0.00013 21.3 0.5 0.00026 20.3 0.5 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GAX12527.1 - 0.00017 20.5 1.2 0.018 13.8 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 GAX12527.1 - 0.00053 19.4 1.3 0.00078 18.9 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX12527.1 - 0.0078 16.8 1.0 2 9.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX12527.1 - 0.082 12.1 1.2 0.16 11.2 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain PALP PF00291.25 GAX12527.1 - 0.093 12.1 0.0 0.35 10.2 0.0 2.0 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Pyr_redox_3 PF13738.6 GAX12527.1 - 0.11 11.7 0.4 0.3 10.3 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CAP18_C PF12153.8 GAX12527.1 - 0.26 11.2 1.0 0.49 10.3 1.0 1.4 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) DENN PF02141.21 GAX12529.1 - 7.9e-42 143.3 2.3 7.9e-42 143.3 2.3 2.7 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 GAX12529.1 - 1.7e-08 35.1 4.9 1.8e-08 35.0 1.8 2.8 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 GAX12529.1 - 6.2e-05 22.9 0.4 0.00027 20.8 0.4 2.2 1 0 0 1 1 1 1 dDENN domain ArfGap PF01412.18 GAX12529.1 - 0.004 17.2 0.8 2.3 8.3 0.0 3.4 2 1 0 2 2 2 2 Putative GTPase activating protein for Arf IQ PF00612.27 GAX12529.1 - 2.2 8.3 12.2 0.34 10.8 1.2 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif His_Phos_1 PF00300.22 GAX12530.1 - 4.4e-30 104.8 1.2 5.5e-23 81.7 0.7 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ebp2 PF05890.12 GAX12531.1 - 1.6e-52 178.7 22.4 1.6e-52 178.7 22.4 2.2 3 1 0 3 3 3 1 Eukaryotic rRNA processing protein EBP2 AA_kinase PF00696.28 GAX12532.1 - 4.5e-47 160.7 2.4 5.3e-47 160.4 2.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family Methyltransf_21 PF05050.12 GAX12533.1 - 1.5e-06 28.3 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain zf-CSL PF05207.13 GAX12534.1 - 1.4e-20 72.7 1.1 1.4e-20 72.7 1.1 1.7 2 0 0 2 2 2 1 CSL zinc finger GP24_25 PF17388.2 GAX12534.1 - 0.062 13.3 0.6 0.083 12.9 0.6 1.3 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 eIF-5a PF01287.20 GAX12535.1 - 5.3e-16 58.5 0.1 8.7e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Pantoate_transf PF02548.15 GAX12536.1 - 1.1e-99 333.1 1.7 1.5e-99 332.6 1.7 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 GAX12536.1 - 0.0056 16.6 0.4 0.028 14.2 0.1 2.2 2 1 0 3 3 3 1 Asp/Glu/Hydantoin racemase WD40 PF00400.32 GAX12537.1 - 4.7e-27 93.7 11.5 2.8e-05 24.8 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 GAX12537.1 - 3.3e-25 88.1 1.7 4.9e-25 87.6 0.4 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 GAX12537.1 - 1.1e-05 25.7 4.7 1 9.7 0.0 4.7 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX12537.1 - 0.013 14.5 0.2 10 5.0 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAX12537.1 - 0.029 13.0 3.8 2.9 6.4 0.2 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 DEAD PF00270.29 GAX12538.1 - 3e-15 56.4 0.0 1.8e-14 53.9 0.1 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12538.1 - 1.3e-10 41.6 0.0 9.7e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ATPase PF06745.13 GAX12538.1 - 0.021 14.2 1.1 2 7.7 0.3 2.3 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 GAX12538.1 - 0.043 12.9 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 GAX12538.1 - 0.045 14.0 0.1 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAX12538.1 - 0.15 11.2 0.2 17 4.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.12 GAX12538.1 - 0.24 10.8 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein PDZ_6 PF17820.1 GAX12539.1 - 2e-07 30.7 0.0 4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX12539.1 - 0.00084 19.6 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX12539.1 - 0.0042 17.4 0.0 0.0069 16.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Nucleoporin_FG PF13634.6 GAX12539.1 - 0.24 12.3 12.5 0.99 10.3 1.0 3.8 2 1 2 4 4 4 0 Nucleoporin FG repeat region DUF3841 PF12952.7 GAX12540.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3841) DUF1517 PF07466.11 GAX12542.1 - 1.5e-69 233.8 0.1 2.5e-38 132.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1517) DUF4381 PF14316.6 GAX12542.1 - 0.00026 21.2 0.5 0.23 11.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) NolX PF05819.11 GAX12542.1 - 0.0019 17.6 0.3 0.65 9.3 0.1 2.2 2 0 0 2 2 2 2 NolX protein Spectrin_like PF18373.1 GAX12542.1 - 0.07 13.2 0.2 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Spectrin like domain Epimerase PF01370.21 GAX12543.1 - 1.7e-12 47.3 0.0 7.1e-11 42.0 0.0 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX12543.1 - 1.1e-07 31.3 0.1 5.2e-06 25.8 0.1 2.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAX12543.1 - 2.6e-07 30.7 0.0 6.1e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX12543.1 - 7.7e-06 25.1 0.0 0.016 14.2 0.0 2.7 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX12543.1 - 9.3e-05 21.7 1.9 0.19 10.9 0.1 3.2 2 1 1 3 3 3 2 Male sterility protein NmrA PF05368.13 GAX12543.1 - 0.00018 21.2 0.0 0.00079 19.0 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family PA PF02225.22 GAX12544.1 - 4.6e-09 36.2 0.0 1.9e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 PA domain Phage_holin_2_4 PF16082.5 GAX12544.1 - 0.0052 16.5 0.7 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like Thioredoxin_4 PF13462.6 GAX12544.1 - 0.027 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin PA PF02225.22 GAX12545.1 - 5.9e-10 39.0 0.0 2e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 PA domain Acetyltransf_10 PF13673.7 GAX12546.1 - 8.7e-17 61.3 0.2 1.4e-16 60.6 0.2 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX12546.1 - 7.6e-13 48.7 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX12546.1 - 1e-11 45.1 0.1 1.6e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX12546.1 - 1.8e-06 27.8 0.1 2.8e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 GAX12546.1 - 2.1e-05 24.3 0.1 2.9e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 GAX12546.1 - 0.0027 17.8 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAX12546.1 - 0.066 13.3 0.1 1.2 9.2 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CENP-B_dimeris PF09026.10 GAX12547.1 - 0.024 15.0 0.4 0.024 15.0 0.4 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF1737 PF08410.10 GAX12547.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) DUF3246 PF11596.8 GAX12547.1 - 0.087 12.2 8.4 1.3 8.4 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PBP1_TM PF14812.6 GAX12547.1 - 1.4 9.4 15.4 1.5 9.2 2.9 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 GAX12547.1 - 9.5 6.3 7.8 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 YL1 nuclear protein TGT PF01702.18 GAX12548.1 - 4.5e-96 322.1 0.0 2.4e-94 316.4 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase TINF2_N PF14973.6 GAX12549.1 - 0.066 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus HAD_2 PF13419.6 GAX12550.1 - 5.3e-21 75.5 0.0 1.7e-20 73.9 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX12550.1 - 2.9e-15 57.1 0.1 9e-15 55.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX12550.1 - 4.5e-05 23.4 0.0 9.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like PhyH PF05721.13 GAX12551.1 - 1.5e-05 25.4 0.1 2.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_11 PF08241.12 GAX12551.1 - 0.042 14.5 0.0 0.14 12.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF1415 PF07209.12 GAX12552.1 - 1.9e-12 47.3 0.0 5e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1415) LRR_6 PF13516.6 GAX12553.1 - 6e-47 153.7 42.2 8.4e-05 22.3 0.1 17.0 18 0 0 18 18 18 12 Leucine Rich repeat LRR_4 PF12799.7 GAX12553.1 - 6.6e-19 67.7 32.7 0.00055 20.3 0.4 11.6 10 4 2 13 13 13 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX12553.1 - 2.9e-14 51.4 22.1 9.1 7.3 0.0 15.9 18 0 0 18 18 18 3 Leucine Rich Repeat LRR_8 PF13855.6 GAX12553.1 - 7.2e-10 38.5 43.5 0.0058 16.4 0.6 10.8 7 5 0 8 8 8 4 Leucine rich repeat LRR_9 PF14580.6 GAX12553.1 - 0.0042 16.6 2.0 0.61 9.6 0.1 3.6 3 1 1 4 4 4 1 Leucine-rich repeat UbiA PF01040.18 GAX12554.1 - 6.2e-49 166.6 18.3 7.8e-49 166.2 18.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family SesA PF17107.5 GAX12555.1 - 1.6 8.9 3.7 83 3.4 0.2 5.0 6 1 1 7 7 7 0 N-terminal domain on NACHT_NTPase and P-loop NTPases H_PPase PF03030.16 GAX12556.1 - 2e-18 66.4 2.5 3.3e-18 65.7 2.2 1.5 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase Peptidase_S26 PF10502.9 GAX12557.1 - 2.3e-06 27.4 0.0 7.6e-05 22.5 0.0 2.5 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 GAX12557.1 - 0.00055 19.8 0.0 0.0023 17.9 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like BDHCT_assoc PF16204.5 GAX12558.1 - 0.69 9.6 7.4 2 8.1 7.4 1.8 1 1 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Trigger_N PF05697.13 GAX12559.1 - 5.5e-21 75.4 0.0 5.5e-21 75.4 0.0 3.7 2 1 1 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 GAX12559.1 - 1.3e-08 35.0 8.4 1.3e-08 35.0 8.4 2.6 1 1 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 GAX12559.1 - 1.2e-07 32.0 0.2 4.2e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase POTRA PF07244.15 GAX12559.1 - 0.021 15.4 4.4 1.9 9.1 0.0 4.3 4 1 0 4 4 4 0 Surface antigen variable number repeat Sucrose_synth PF00862.19 GAX12559.1 - 0.047 12.0 2.2 0.08 11.2 2.2 1.4 1 1 0 1 1 1 0 Sucrose synthase EIIBC-GUT_C PF07663.11 GAX12559.1 - 0.056 13.6 0.0 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II C-terminus TINF2_N PF14973.6 GAX12559.1 - 0.94 9.8 4.3 4.5 7.6 0.8 2.6 2 1 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF2018 PF09442.10 GAX12559.1 - 1.8 9.6 5.1 1.1 10.2 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) SurA_N_2 PF13623.6 GAX12559.1 - 7.2 6.5 9.1 5.9 6.8 5.0 2.6 1 1 2 3 3 3 0 SurA N-terminal domain Beach PF02138.18 GAX12560.1 - 1.9e-113 378.5 0.1 3e-113 377.8 0.1 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAX12560.1 - 1.7e-09 37.7 1.2 3.8e-09 36.6 0.2 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAX12560.1 - 4.5e-06 26.9 0.2 1.1e-05 25.6 0.2 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 GAX12560.1 - 2e-05 25.2 6.9 0.19 12.6 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4800 PF16057.5 GAX12560.1 - 0.049 12.9 0.4 0.11 11.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Arm PF00514.23 GAX12560.1 - 0.11 12.6 0.1 4.2 7.6 0.1 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SATase_N PF06426.14 GAX12561.1 - 3.9e-36 123.6 0.5 6.6e-36 122.9 0.1 1.6 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 GAX12561.1 - 2.7e-12 45.9 7.0 1.6e-08 33.9 0.6 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAX12561.1 - 7.9e-05 22.3 2.9 7.9e-05 22.3 2.9 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Arteri_env PF01606.16 GAX12562.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Arterivirus envelope protein AKAP7_NLS PF10469.9 GAX12563.1 - 8e-07 29.1 0.1 1.6e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain GH43_C PF16369.5 GAX12563.1 - 0.011 16.4 0.1 0.24 12.1 0.0 2.8 3 0 0 3 3 3 0 C-terminal lipocalin-like domain VWA_2 PF13519.6 GAX12564.1 - 7.5e-14 52.3 0.3 2.4e-13 50.7 0.3 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAX12564.1 - 1.5e-10 41.6 0.4 2.4e-10 40.9 0.4 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX12564.1 - 1.5e-07 31.5 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 GAX12564.1 - 0.03 14.4 0.2 0.053 13.6 0.2 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF5338 PF17273.2 GAX12564.1 - 0.11 12.6 0.1 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5338) VWA_2 PF13519.6 GAX12566.1 - 1.2e-14 54.9 0.1 2e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAX12566.1 - 2e-10 41.2 0.0 3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX12566.1 - 1.9e-08 34.4 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 GAX12566.1 - 0.0028 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 GAX12566.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DrsE PF02635.15 GAX12566.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 DsrE/DsrF-like family LRR_4 PF12799.7 GAX12567.1 - 2.2e-17 62.9 17.4 3.6e-05 24.0 0.4 5.2 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX12567.1 - 4.9e-16 58.2 12.9 4e-08 32.9 1.3 4.5 2 1 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 GAX12567.1 - 4.1e-07 29.6 18.2 0.14 12.8 0.2 8.1 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 GAX12567.1 - 4.7e-07 29.4 10.9 1 9.6 0.0 7.2 7 0 0 7 7 7 3 Leucine Rich repeat PLAC8 PF04749.17 GAX12568.1 - 0.0038 18.2 9.3 0.0056 17.6 9.3 1.2 1 0 0 1 1 1 1 PLAC8 family Glyco_hydro_30C PF17189.4 GAX12568.1 - 0.037 14.2 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain Cupin_8 PF13621.6 GAX12571.1 - 1.2e-38 133.3 0.1 2.3e-38 132.3 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX12571.1 - 1.1e-10 41.5 0.6 5.5e-10 39.2 0.6 2.1 1 1 0 1 1 1 1 Cupin superfamily protein SET PF00856.28 GAX12571.1 - 2.2e-09 37.9 0.2 2e-08 34.8 0.2 2.6 1 1 0 1 1 1 1 SET domain JmjC PF02373.22 GAX12571.1 - 0.00017 22.0 0.1 0.00038 20.8 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 GAX12571.1 - 0.0015 18.2 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CSTF_C PF14304.6 GAX12571.1 - 0.073 12.7 0.1 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal RRN3 PF05327.11 GAX12571.1 - 0.26 9.8 1.3 0.42 9.1 1.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_ligase_A_M PF01068.21 GAX12572.1 - 3.5e-52 177.0 0.1 7e-52 176.0 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAX12572.1 - 1.1e-39 136.5 0.2 3.7e-39 134.8 0.2 1.9 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAX12572.1 - 1.7e-23 83.1 0.0 4.2e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 GAX12572.1 - 8e-05 23.0 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 GAX12572.1 - 0.15 12.1 0.3 15 5.7 0.0 2.9 2 0 0 2 2 2 0 DNA ligase OB-like domain CDC45 PF02724.14 GAX12572.1 - 1.2 7.3 13.2 2.3 6.4 13.2 1.4 1 0 0 1 1 1 0 CDC45-like protein HSF_DNA-bind PF00447.17 GAX12573.1 - 1.5e-17 64.0 0.5 3.6e-17 62.8 0.5 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 GAX12574.1 - 5.3e-18 65.4 0.4 1e-17 64.5 0.4 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Cofac_haem_bdg PF04187.13 GAX12575.1 - 5.1e-45 154.1 0.0 2.7e-44 151.7 0.0 2.1 3 0 0 3 3 3 1 Haem-binding uptake, Tiki superfamily, ChaN Epimerase PF01370.21 GAX12575.1 - 2.1e-07 30.7 0.0 3.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PucR PF07905.11 GAX12575.1 - 0.17 12.2 0.1 27 5.1 0.0 3.6 3 1 0 3 3 3 0 Purine catabolism regulatory protein-like family FTR1 PF03239.14 GAX12576.1 - 1e-09 38.0 10.2 2e-09 37.1 9.7 1.7 1 1 0 1 1 1 1 Iron permease FTR1 family PrgI PF12666.7 GAX12576.1 - 0.011 16.4 1.0 1.5 9.6 0.1 2.7 2 0 0 2 2 2 0 PrgI family protein DUF4231 PF14015.6 GAX12576.1 - 0.13 12.7 3.0 4.4 7.8 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Wzy_C PF04932.15 GAX12576.1 - 0.18 11.5 2.6 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 O-Antigen ligase DUF3792 PF12670.7 GAX12576.1 - 0.88 9.7 9.6 3.7 7.7 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF4342 PF14242.6 GAX12576.1 - 1.5 8.9 4.4 5.8 7.0 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Cytochrom_B561 PF03188.16 GAX12577.1 - 7.9e-10 39.0 1.8 1.5e-09 38.1 1.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Fcf2 PF08698.11 GAX12578.1 - 1.8e-28 98.7 0.0 1.8e-28 98.7 0.0 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing FKBP_C PF00254.28 GAX12579.1 - 1.9e-09 37.7 0.0 4.6e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 GAX12579.1 - 0.0025 17.5 0.1 0.0072 16.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX12579.1 - 0.0039 17.3 0.8 0.014 15.5 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX12579.1 - 0.0066 16.8 0.3 2.2 8.9 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX12579.1 - 0.021 14.9 0.8 0.16 12.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1957 PF09210.11 GAX12579.1 - 0.082 13.3 2.3 0.13 12.7 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1957) Fis1_TPR_C PF14853.6 GAX12579.1 - 0.13 12.3 0.6 0.72 10.0 0.2 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Vpu PF00558.19 GAX12579.1 - 0.4 10.5 1.8 1.1 9.1 1.8 1.7 1 0 0 1 1 1 0 Vpu protein DUF4111 PF13427.6 GAX12579.1 - 0.41 10.8 3.6 8.4 6.6 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) ABC2_membrane PF01061.24 GAX12580.1 - 3.6e-38 131.1 17.1 5.8e-38 130.4 17.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX12580.1 - 1e-20 74.6 0.0 1.6e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX12580.1 - 7.1e-12 45.1 8.2 1.5e-11 44.0 8.2 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAX12580.1 - 5.4e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 GAX12580.1 - 8.7e-05 22.5 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX12580.1 - 0.0084 15.6 0.1 0.082 12.3 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAX12580.1 - 0.0086 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAX12580.1 - 0.03 14.4 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAX12580.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX12580.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAX12580.1 - 0.063 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX12580.1 - 0.069 13.7 0.6 0.15 12.6 0.6 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 GAX12580.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 GAX12580.1 - 0.18 12.4 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Chorein_N PF12624.7 GAX12581.1 - 3.2e-19 69.1 1.4 7.2e-19 68.0 0.4 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 GAX12581.1 - 4.1e-13 49.3 0.0 3.4e-05 23.4 0.0 2.9 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 GAX12581.1 - 0.0026 17.6 0.3 0.0056 16.5 0.3 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal PDZ_6 PF17820.1 GAX12581.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 GAX12581.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 GAX12581.1 - 0.18 12.2 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 PDZ domain VPS13_C PF16909.5 GAX12582.1 - 7.6e-31 107.2 0.9 1.3e-26 93.5 0.3 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal DUF4404 PF14357.6 GAX12582.1 - 3.6 8.3 7.1 30 5.3 7.1 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) AAA_23 PF13476.6 GAX12582.1 - 4.4 7.8 9.5 0.31 11.5 4.0 2.0 2 1 0 2 2 2 0 AAA domain DUF2142 PF09913.9 GAX12583.1 - 0.028 13.3 0.4 0.028 13.3 0.4 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) Cyt_c_ox_IV PF12270.8 GAX12583.1 - 0.077 13.1 3.5 0.36 11.0 0.4 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV Mem_trans PF03547.18 GAX12583.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Membrane transport protein KTI12 PF08433.10 GAX12584.1 - 5.8e-15 55.5 0.1 8.4e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAX12584.1 - 4.9e-11 43.0 0.3 1.7e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX12584.1 - 1.3e-05 25.5 0.0 5.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAX12584.1 - 0.00028 20.9 0.3 0.00059 19.9 0.1 1.6 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 GAX12584.1 - 0.00082 18.7 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ATPase PF06745.13 GAX12584.1 - 0.0024 17.3 0.0 0.006 16.0 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.6 GAX12584.1 - 0.0026 18.3 0.1 0.014 15.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX12584.1 - 0.0026 18.3 0.0 0.0068 16.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAX12584.1 - 0.0093 16.4 0.9 0.032 14.6 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 GAX12584.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 GAX12584.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GAX12584.1 - 0.015 15.0 0.1 0.1 12.3 0.0 2.1 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 GAX12584.1 - 0.017 15.0 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase cobW PF02492.19 GAX12584.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAX12584.1 - 0.024 14.5 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 GAX12584.1 - 0.029 13.5 0.2 0.059 12.5 0.2 1.3 1 1 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.22 GAX12584.1 - 0.031 13.5 0.5 0.11 11.6 0.0 2.2 2 2 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 GAX12584.1 - 0.077 13.4 0.0 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX12584.1 - 0.12 12.4 0.1 0.48 10.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAX12584.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX12584.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase SKI PF01202.22 GAX12584.1 - 0.68 10.0 2.4 47 4.1 0.1 3.4 3 1 1 4 4 4 0 Shikimate kinase RNase_HII PF01351.18 GAX12585.1 - 5.7e-18 65.5 0.0 9.2e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease HII Methyltransf_11 PF08241.12 GAX12585.1 - 1.5e-08 35.2 0.0 4.1e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX12585.1 - 5.7e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAX12585.1 - 0.0001 22.2 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX12585.1 - 0.00025 21.7 0.0 0.00064 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX12585.1 - 0.039 14.7 0.0 0.15 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Iso_dh PF00180.20 GAX12585.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase cobW PF02492.19 GAX12586.1 - 5.9e-56 188.8 0.9 8e-56 188.4 0.9 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX12586.1 - 3.2e-18 65.4 0.0 5.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAX12586.1 - 0.00067 19.6 0.5 1 9.2 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 GAX12586.1 - 0.0021 17.5 0.9 0.066 12.7 0.2 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family T2SSE PF00437.20 GAX12586.1 - 0.017 14.2 0.2 0.031 13.3 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 GAX12586.1 - 0.021 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 GAX12586.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAX12586.1 - 0.046 14.1 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 GAX12586.1 - 0.057 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 GAX12586.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX12586.1 - 0.081 13.0 0.5 0.33 11.0 0.5 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 GAX12586.1 - 0.083 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.14 GAX12586.1 - 0.098 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 GAX12586.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX12586.1 - 0.14 12.7 0.1 0.32 11.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 GAX12586.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.27 GAX12586.1 - 0.35 10.4 3.1 6.4 6.3 3.2 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 GAX12586.1 - 5 7.6 10.5 72 3.8 10.5 2.2 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpb4 PF03874.16 GAX12587.1 - 5.1e-09 36.5 0.2 7.2e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 TraF_2 PF13729.6 GAX12587.1 - 0.0052 16.2 0.8 0.022 14.1 0.3 1.7 1 1 1 2 2 2 2 F plasmid transfer operon, TraF, protein DUF4972 PF16342.5 GAX12587.1 - 0.024 14.3 0.1 0.052 13.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) PEP-utilisers_N PF05524.13 GAX12587.1 - 0.048 13.8 2.7 0.095 12.9 2.4 1.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1729 PF08354.10 GAX12587.1 - 0.054 12.4 0.1 0.065 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) LprI PF07007.12 GAX12587.1 - 0.14 12.8 0.1 0.17 12.5 0.1 1.2 1 0 0 1 1 1 0 Lysozyme inhibitor LprI RINT1_TIP1 PF04437.13 GAX12588.1 - 0.096 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DEAD PF00270.29 GAX12589.1 - 1.4e-19 70.5 0.2 1.6e-17 63.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12589.1 - 5.7e-19 68.5 0.0 1.4e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAX12589.1 - 2.1e-08 34.8 3.4 4.9e-08 33.6 1.2 2.7 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 GAX12589.1 - 0.00039 20.5 0.0 0.0071 16.4 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RasGEF_N_2 PF14663.6 GAX12589.1 - 0.03 14.7 0.0 0.097 13.1 0.0 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HRDC PF00570.23 GAX12589.1 - 0.037 14.0 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 HRDC domain AAA_22 PF13401.6 GAX12589.1 - 0.16 12.2 0.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Alpha_kinase PF02816.18 GAX12590.1 - 6.8e-38 130.6 0.1 5.2e-25 88.7 0.1 2.3 2 0 0 2 2 2 2 Alpha-kinase family VWA_2 PF13519.6 GAX12590.1 - 0.00028 21.5 0.0 0.00078 20.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain V-SNARE_C PF12352.8 GAX12591.1 - 6.3e-10 39.2 0.8 6.3e-10 39.2 0.8 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAX12591.1 - 0.00077 19.3 0.2 0.00077 19.3 0.2 2.2 1 1 1 2 2 2 1 Sec20 FUSC PF04632.12 GAX12591.1 - 0.04 12.5 4.4 0.046 12.2 4.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pro_isomerase PF00160.21 GAX12592.1 - 1.6e-39 135.7 0.0 2.1e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_23 PF13489.6 GAX12593.1 - 2e-11 44.0 0.0 3.9e-11 43.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX12593.1 - 9.2e-11 41.8 0.0 0.0005 19.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAX12593.1 - 1.5e-08 35.2 0.0 4e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX12593.1 - 6.4e-08 33.2 0.0 2.4e-05 24.9 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAX12593.1 - 1.3e-07 32.2 0.0 3.4e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 GAX12593.1 - 0.00017 20.8 0.0 0.0042 16.2 0.0 2.2 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 GAX12593.1 - 0.0021 17.7 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 GAX12593.1 - 0.0034 16.8 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 GAX12593.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCSK9_C3 PF18463.1 GAX12594.1 - 0.082 13.1 0.9 0.19 12.0 0.9 1.6 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Spo7 PF03907.13 GAX12594.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Spo7-like protein Rib_5-P_isom_A PF06026.14 GAX12595.1 - 8e-66 220.9 0.0 1e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 GAX12595.1 - 0.033 14.1 0.0 1 9.3 0.0 2.3 1 1 0 2 2 2 0 DeoR C terminal sensor domain Aminotran_3 PF00202.21 GAX12597.1 - 5.2e-80 269.1 0.0 6.3e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF72 PF01904.18 GAX12597.1 - 0.17 12.0 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF72 Glycos_transf_2 PF00535.26 GAX12598.1 - 3e-15 56.4 0.0 3.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX12598.1 - 1.5e-06 28.2 0.0 4.1e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GAX12598.1 - 0.00029 21.3 0.0 0.00051 20.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAX12598.1 - 0.00054 19.5 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 tRNA_lig_CPD PF08302.11 GAX12598.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain adh_short PF00106.25 GAX12599.1 - 1.6e-08 34.2 1.5 3.1e-05 23.5 1.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX12599.1 - 7.5e-07 28.9 1.1 6.2e-06 25.9 0.2 2.6 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAX12599.1 - 0.00034 20.2 0.1 0.019 14.5 0.1 2.6 2 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family CRAL_TRIO PF00650.20 GAX12600.1 - 1.6e-10 40.9 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CwfJ_C_2 PF04676.14 GAX12601.1 - 6.3e-20 71.9 0.1 1.3e-19 70.9 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 GAX12601.1 - 4e-19 68.7 0.0 6.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GAD-like PF08887.11 GAX12602.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 GAD-like domain MoCF_biosynth PF00994.24 GAX12603.1 - 3.2e-26 91.7 0.1 5.4e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF1244 PF06844.11 GAX12603.1 - 7.7e-23 80.4 8.5 2.6e-20 72.3 8.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1244) TCRP1 PF14944.6 GAX12603.1 - 0.071 13.1 2.5 0.1 12.5 2.5 1.3 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 Nup188_C PF18378.1 GAX12603.1 - 2.2 7.1 4.8 1.1 8.0 0.0 2.5 3 0 0 3 3 3 0 Nuclear pore protein NUP188 C-terminal domain VCBS PF13517.6 GAX12605.1 - 2.8e-10 40.6 12.8 0.0014 19.2 0.1 6.2 6 1 0 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAX12605.1 - 6.8e-07 29.3 12.3 0.0068 16.5 1.0 4.3 3 0 0 3 3 3 3 FG-GAP repeat Dockerin_1 PF00404.18 GAX12605.1 - 0.026 14.7 0.2 19 5.5 0.0 3.9 3 0 0 3 3 3 0 Dockerin type I domain TcdB_toxin_midN PF12256.8 GAX12605.1 - 0.054 12.9 1.3 7.4 5.9 0.0 3.6 4 0 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region Presenilin PF01080.17 GAX12605.1 - 3 6.5 5.9 4.1 6.1 5.9 1.1 1 0 0 1 1 1 0 Presenilin Nucleo_P87 PF07267.11 GAX12605.1 - 3.7 6.3 7.2 5.3 5.8 7.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HU-DNA_bdg PF14848.6 GAX12606.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA-binding domain CLASP_N PF12348.8 GAX12606.1 - 1.5 8.4 6.8 0.21 11.1 0.2 2.8 3 1 0 3 3 3 0 CLASP N terminal FAD_binding_3 PF01494.19 GAX12607.1 - 2e-27 96.3 0.0 2.8e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAX12607.1 - 4.3e-07 29.5 0.1 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX12607.1 - 2.8e-05 23.9 0.7 0.0052 16.4 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 GAX12607.1 - 3.4e-05 23.1 0.0 5.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 GAX12607.1 - 0.00034 21.1 0.7 0.44 11.1 0.1 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX12607.1 - 0.0015 18.7 0.1 0.0044 17.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAX12607.1 - 0.003 16.5 0.1 0.15 10.9 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 GAX12607.1 - 0.089 11.5 0.9 2.1 7.0 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAX12607.1 - 0.17 11.1 2.5 6.6 5.9 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX12607.1 - 0.18 10.9 0.1 0.68 8.9 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 GAX12607.1 - 0.35 9.9 4.4 8.2 5.4 0.3 2.8 2 1 0 2 2 2 0 Lycopene cyclase protein HAD_2 PF13419.6 GAX12610.1 - 1.3e-05 25.4 1.3 0.024 14.7 0.2 3.3 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX12610.1 - 0.00011 22.1 0.0 0.00028 20.9 0.0 1.7 1 1 0 1 1 1 1 HAD-hyrolase-like NADase_NGA PF07461.11 GAX12610.1 - 0.0018 17.2 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Nicotine adenine dinucleotide glycohydrolase (NADase) CK2S PF15011.6 GAX12610.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Casein Kinase 2 substrate DnaJ_C PF01556.18 GAX12611.1 - 1.1e-40 139.2 0.0 2.1e-40 138.2 0.0 1.5 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX12611.1 - 8.4e-25 86.7 1.1 1.4e-24 85.9 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAX12611.1 - 4e-12 46.3 19.8 8.3e-12 45.3 19.8 1.6 1 0 0 1 1 1 1 DnaJ central domain TackOD1 PF18551.1 GAX12611.1 - 0.49 10.0 5.1 0.62 9.7 0.4 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 GAX12611.1 - 0.69 10.0 11.4 3.8 7.6 11.4 2.1 1 1 0 1 1 1 0 Double zinc ribbon Anti-TRAP PF15777.5 GAX12611.1 - 0.7 9.9 19.7 3 7.9 4.5 3.4 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 GAX12611.1 - 1.2 9.2 7.0 2.5 8.1 7.0 1.5 1 0 0 1 1 1 0 zinc-ribbons zinc_ribbon_15 PF17032.5 GAX12611.1 - 5.9 7.7 7.4 13 6.6 7.4 1.6 1 1 0 1 1 1 0 zinc-ribbon family CBS PF00571.28 GAX12612.1 - 9.4e-15 54.8 0.1 1.8e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain SpoIIE PF07228.12 GAX12612.1 - 4.3e-09 36.6 0.0 1.2e-07 31.9 0.0 2.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAX12612.1 - 1.1e-06 28.4 0.0 0.011 15.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Sad1_UNC PF07738.13 GAX12613.1 - 1.3e-19 70.6 0.0 2.3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4382 PF14321.6 GAX12613.1 - 0.017 15.4 0.5 0.047 14.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4382) Peptidase_S49_N PF08496.10 GAX12614.1 - 0.079 13.0 2.1 1.7 8.7 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Trp_Tyr_perm PF03222.13 GAX12615.1 - 5.2e-27 94.9 12.0 4.4e-26 91.8 12.0 1.9 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 GAX12615.1 - 0.0016 17.2 7.2 0.0022 16.8 7.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Cnl2_NKP2 PF09447.10 GAX12615.1 - 0.039 14.1 0.2 0.039 14.1 0.2 1.8 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Bromodomain PF00439.25 GAX12616.1 - 3.8e-23 81.3 0.3 7.6e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 GAX12616.1 - 8.7e-12 45.3 0.1 2.5e-10 40.6 0.2 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX12616.1 - 8.7e-09 35.4 0.1 1.8e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX12616.1 - 5.4e-08 33.1 0.1 1e-07 32.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX12616.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 GAX12616.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 GAX12616.1 - 0.17 11.3 3.0 2 7.8 0.0 2.6 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Brix PF04427.18 GAX12617.1 - 4e-30 105.4 0.1 5.3e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain Trypsin_2 PF13365.6 GAX12619.1 - 2.5e-33 116.1 0.5 4.5e-33 115.3 0.5 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX12619.1 - 6.9e-15 55.5 0.1 1.7e-14 54.2 0.1 1.6 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 GAX12619.1 - 3.6e-12 46.4 0.1 7.2e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX12619.1 - 7.3e-05 22.5 4.3 0.0068 16.2 0.4 2.7 2 0 0 2 2 2 2 PDZ domain Peptidase_S29 PF02907.15 GAX12619.1 - 0.002 17.8 0.2 0.016 15.0 0.0 2.3 2 1 1 3 3 3 1 Hepatitis C virus NS3 protease PDZ PF00595.24 GAX12619.1 - 0.008 16.5 3.1 0.38 11.2 3.1 2.7 1 1 0 1 1 1 1 PDZ domain Peptidase_S32 PF05579.13 GAX12619.1 - 0.011 15.0 0.3 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 GAX12619.1 - 0.042 12.5 1.1 0.26 9.9 0.5 1.9 2 0 0 2 2 2 0 Peptidase S46 GRASP55_65 PF04495.14 GAX12619.1 - 0.065 13.6 0.0 0.44 10.9 0.0 2.1 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Slu7 PF11708.8 GAX12620.1 - 6e-82 275.4 9.7 6e-82 275.4 9.7 2.8 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-MYND PF01753.18 GAX12621.1 - 1.8e-06 27.9 19.3 3.5e-06 27.0 19.3 1.5 1 0 0 1 1 1 1 MYND finger Zip PF02535.22 GAX12622.1 - 7e-37 127.4 22.4 4.3e-26 91.9 9.9 2.6 2 1 1 3 3 3 2 ZIP Zinc transporter DUF1129 PF06570.11 GAX12622.1 - 0.37 10.2 2.7 0.17 11.3 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PDGF_N PF04692.13 GAX12622.1 - 1.3 9.8 2.8 16 6.3 0.0 2.3 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region DUF2427 PF10348.9 GAX12622.1 - 1.4 8.7 5.0 0.7 9.7 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) DFP PF04127.15 GAX12623.1 - 0.091 12.6 0.8 0.26 11.1 0.1 2.2 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein SpoIIIAH PF12685.7 GAX12623.1 - 0.49 10.2 7.2 0.23 11.3 3.5 2.3 2 1 0 2 2 2 0 SpoIIIAH-like protein Peptidase_C1 PF00112.23 GAX12624.1 - 1.9e-70 237.3 0.5 2.8e-70 236.8 0.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX12624.1 - 6.7e-15 55.3 3.2 1.1e-14 54.6 3.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAX12624.1 - 1.9e-05 23.6 0.5 0.038 12.8 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PseudoU_synth_1 PF01416.20 GAX12625.1 - 7.8e-19 68.1 0.0 1.8e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 GAX12625.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Peptidase_S41 PF03572.18 GAX12626.1 - 1e-42 145.5 0.6 1.7e-42 144.8 0.6 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 GAX12626.1 - 8.2e-11 42.1 0.2 2.2e-10 40.7 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX12626.1 - 1.6e-07 31.5 0.1 3.1e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX12626.1 - 2.4e-07 30.5 0.1 6.3e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_C1 PF14684.6 GAX12626.1 - 8.4e-07 29.0 1.0 1.4e-06 28.2 1.0 1.3 1 0 0 1 1 1 1 Tricorn protease C1 domain Efg1 PF10153.9 GAX12628.1 - 0.094 13.1 2.4 0.15 12.5 2.4 1.3 1 0 0 1 1 1 0 rRNA-processing protein Efg1 IpaC_SipC PF09599.10 GAX12628.1 - 0.15 11.5 0.8 0.21 11.1 0.8 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) Seryl_tRNA_N PF02403.22 GAX12628.1 - 0.16 12.2 3.1 0.22 11.7 3.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CHD5 PF04420.14 GAX12628.1 - 0.29 11.0 4.5 0.83 9.5 4.5 1.7 1 1 0 1 1 1 0 CHD5-like protein DivIC PF04977.15 GAX12628.1 - 9.2 6.1 9.8 6.7 6.6 1.8 2.3 1 1 1 2 2 2 0 Septum formation initiator SpoU_methylase PF00588.19 GAX12629.1 - 3e-27 95.5 0.0 4.8e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family Syntaxin-6_N PF09177.11 GAX12629.1 - 0.11 13.0 0.4 0.3 11.6 0.4 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal GvpG PF05120.12 GAX12629.1 - 0.19 11.8 0.7 0.35 10.9 0.7 1.4 1 0 0 1 1 1 0 Gas vesicle protein G MatE PF01554.18 GAX12630.1 - 5.8e-10 39.0 22.4 1.7e-08 34.3 1.9 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAX12630.1 - 5.7e-07 29.7 1.8 5.7e-07 29.7 1.8 3.9 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Plasmid_stab_B PF10784.9 GAX12630.1 - 0.047 13.5 1.1 0.082 12.7 0.1 2.0 2 0 0 2 2 2 0 Plasmid stability protein Trypsin PF00089.26 GAX12631.1 - 9.9e-38 130.1 0.0 1.3e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX12631.1 - 5.9e-05 24.0 0.0 0.00015 22.7 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1825 PF08855.10 GAX12632.1 - 1.5e-17 63.4 1.6 1.3e-12 47.6 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1825) ROS_MUCR PF05443.11 GAX12632.1 - 0.0055 16.8 0.4 2 8.5 0.0 2.3 2 0 0 2 2 2 2 ROS/MUCR transcriptional regulator protein zf_C2H2_6 PF18450.1 GAX12632.1 - 0.11 12.2 0.3 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Zinc Finger domain ISET-FN3_linker PF16625.5 GAX12632.1 - 1.8 9.1 4.7 1.2 9.7 1.7 2.1 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO Pro_dh PF01619.18 GAX12633.1 - 2.9e-82 276.5 0.1 7.8e-82 275.1 0.1 1.8 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_1 PF00036.32 GAX12633.1 - 1e-05 24.7 0.5 3e-05 23.2 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX12633.1 - 6.9e-05 22.5 0.5 0.00022 20.9 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 GAX12633.1 - 0.00016 21.0 0.3 0.00039 19.8 0.3 1.7 1 0 0 1 1 1 1 EF hand AP_endonuc_2 PF01261.24 GAX12633.1 - 0.0049 16.3 0.0 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel EF-hand_7 PF13499.6 GAX12633.1 - 0.0069 16.8 0.0 0.024 15.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX12633.1 - 0.019 14.8 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair NADH-G_4Fe-4S_3 PF10588.9 GAX12633.1 - 0.16 11.5 0.1 0.47 10.0 0.1 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region HMG_box PF00505.19 GAX12634.1 - 0.0016 18.8 0.9 0.049 14.0 0.1 2.4 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX12634.1 - 0.25 11.9 2.6 8.1 7.1 2.6 2.5 1 1 0 1 1 1 0 HMG-box domain AAA_12 PF13087.6 GAX12635.1 - 4.4e-33 114.6 0.0 7.7e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX12635.1 - 3e-19 69.8 0.0 8.6e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAX12635.1 - 2.4e-09 37.7 0.0 8.3e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX12635.1 - 8.6e-09 35.4 0.0 6.4e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 GAX12635.1 - 0.0035 17.3 0.0 0.0087 16.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DEAD PF00270.29 GAX12635.1 - 0.1 12.4 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 GAX12635.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 GAX12635.1 - 0.16 11.4 0.0 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Aldo_ket_red PF00248.21 GAX12636.1 - 3.8e-48 164.2 0.1 4.9e-48 163.8 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_1 PF00515.28 GAX12637.1 - 1.4e-13 50.0 8.4 1.3e-07 31.1 0.7 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat Prefoldin_2 PF01920.20 GAX12637.1 - 3e-13 49.7 10.1 3e-13 49.7 10.1 3.2 2 1 1 3 3 3 1 Prefoldin subunit TPR_2 PF07719.17 GAX12637.1 - 5.5e-11 41.7 8.7 2.6e-06 27.1 0.6 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX12637.1 - 7.1e-07 28.8 1.9 6.7e-05 22.5 0.1 3.2 1 1 2 3 3 3 1 TPR repeat TPR_16 PF13432.6 GAX12637.1 - 8.5e-07 29.5 1.7 0.001 19.7 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX12637.1 - 9.9e-07 28.8 0.7 0.00061 19.9 0.3 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX12637.1 - 1.4e-06 28.1 9.6 0.0054 16.8 0.4 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX12637.1 - 2.5e-06 27.9 3.1 0.027 15.0 0.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX12637.1 - 4.2e-06 27.1 4.7 0.042 14.7 0.0 4.1 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX12637.1 - 6e-05 23.4 1.9 0.74 10.6 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX12637.1 - 0.00034 20.4 10.7 0.049 13.7 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX12637.1 - 0.00041 20.6 6.5 0.029 14.7 1.1 3.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 GAX12637.1 - 0.0022 17.9 2.9 0.011 15.7 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX12637.1 - 0.0038 16.7 1.0 1.1 8.7 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_17 PF13431.6 GAX12637.1 - 0.0055 17.0 5.8 0.91 10.1 0.2 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX12637.1 - 0.012 15.5 3.4 0.48 10.4 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat IR1-M PF12185.8 GAX12637.1 - 0.026 14.5 0.0 0.078 12.9 0.0 1.9 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Fer4_NifH PF00142.18 GAX12637.1 - 0.096 12.1 1.8 0.15 11.4 1.8 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Prefoldin PF02996.17 GAX12637.1 - 0.1 12.5 0.4 0.1 12.5 0.4 3.6 3 1 0 3 3 3 0 Prefoldin subunit EIF4E-T PF10477.9 GAX12637.1 - 0.33 9.7 6.7 0.46 9.2 6.7 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Cid2 PF09774.9 GAX12637.1 - 0.48 10.8 7.4 0.38 11.2 0.3 2.3 1 1 1 2 2 2 0 Caffeine-induced death protein 2 DUF2894 PF11445.8 GAX12637.1 - 0.59 10.6 9.1 0.11 12.9 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) MIT PF04212.18 GAX12637.1 - 1.4 9.1 9.1 0.52 10.4 0.5 3.9 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 GAX12637.1 - 1.8 8.7 13.4 2 8.6 0.0 4.5 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Syntaxin_2 PF14523.6 GAX12637.1 - 2.1 8.7 16.2 4.9 7.6 9.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DLP_helical PF18709.1 GAX12637.1 - 2.5 7.2 13.2 6.3 5.9 0.3 2.4 2 1 0 2 2 2 0 Dynamin-like helical domain Fib_alpha PF08702.10 GAX12637.1 - 3.7 7.7 13.3 10 6.3 0.3 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family T2SSF PF00482.23 GAX12637.1 - 4 7.4 7.0 0.74 9.8 0.5 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F MCCD1 PF15707.5 GAX12637.1 - 6.5 7.3 14.2 1.5 9.3 0.5 2.7 3 0 0 3 3 2 0 Mitochondrial coiled-coil domain protein 1 HA PF03457.14 GAX12638.1 - 5.4e-37 126.0 1.2 2.2e-19 69.5 0.4 2.3 2 0 0 2 2 2 2 Helicase associated domain RNF220 PF15926.5 GAX12638.1 - 0.00075 19.2 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 DUF2153 PF09921.9 GAX12638.1 - 0.046 13.5 0.2 2.3 8.0 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) Topo_Zn_Ribbon PF08272.11 GAX12638.1 - 0.08 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Afi1 PF07792.12 GAX12638.1 - 0.37 11.3 2.6 0.73 10.3 2.6 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking G6PD_C PF02781.16 GAX12639.1 - 4.9e-97 324.6 0.0 7e-97 324.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAX12639.1 - 7.3e-58 196.1 0.1 1e-57 195.6 0.1 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF4057 PF13266.6 GAX12640.1 - 0.036 13.8 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) 2OG-FeII_Oxy_3 PF13640.6 GAX12641.1 - 6e-16 59.1 0.0 1e-15 58.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAX12641.1 - 5.4e-11 43.0 0.0 1e-10 42.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NACHT PF05729.12 GAX12641.1 - 0.036 14.0 0.1 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain EcoRII-C PF09019.11 GAX12641.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 EcoRII C terminal DUF3677 PF12432.8 GAX12642.1 - 6.1e-05 23.3 0.0 0.0002 21.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) RRM_1 PF00076.22 GAX12643.1 - 2.4e-14 52.9 0.0 3.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bot1p PF12298.8 GAX12644.1 - 0.00017 21.8 0.1 0.00052 20.2 0.1 1.8 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Mrr_N PF14338.6 GAX12644.1 - 0.031 14.4 0.7 0.09 12.9 0.0 2.2 2 0 0 2 2 2 0 Mrr N-terminal domain DUF932 PF06067.11 GAX12644.1 - 0.072 12.9 1.6 0.094 12.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Homoserine_dh PF00742.19 GAX12646.1 - 7e-56 188.9 1.1 1.9e-55 187.4 0.2 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GAX12646.1 - 6.3e-16 59.1 0.1 1.6e-15 57.7 0.1 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAX12646.1 - 0.0048 17.1 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 GAX12646.1 - 0.0066 17.3 0.0 0.015 16.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF563 PF04577.14 GAX12648.1 - 3.2e-22 79.7 0.1 4.6e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Peptidase_S26 PF10502.9 GAX12649.1 - 9.3e-07 28.7 0.0 7.8e-05 22.5 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 GAX12649.1 - 0.0044 17.0 0.0 0.016 15.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like H_PPase PF03030.16 GAX12650.1 - 5.7e-164 547.3 31.5 6.8e-164 547.0 31.5 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Peptidase_S24 PF00717.23 GAX12651.1 - 2e-08 34.1 0.0 0.00043 20.2 0.0 2.4 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 GAX12651.1 - 1e-05 25.3 0.2 0.0016 18.2 0.0 2.9 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 FXR_C1 PF16096.5 GAX12652.1 - 0.99 9.7 4.4 1.9 8.8 4.4 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DHHC PF01529.20 GAX12653.1 - 6.6e-26 91.0 12.9 6.6e-26 91.0 12.9 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase TylF PF05711.11 GAX12654.1 - 2.1e-09 37.0 0.0 1.2e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Macrocin-O-methyltransferase (TylF) TPR_2 PF07719.17 GAX12654.1 - 2e-07 30.6 1.1 0.68 10.2 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX12654.1 - 3.2e-06 26.9 0.5 1.5 9.2 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX12654.1 - 3.7e-06 26.5 0.3 1.7 8.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX12654.1 - 1.1e-05 25.9 2.2 0.0012 19.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX12654.1 - 1.7e-05 25.0 0.8 0.38 11.1 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX12654.1 - 0.00023 21.7 5.3 0.93 10.5 0.0 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat Methyltransf_24 PF13578.6 GAX12654.1 - 0.00025 22.0 0.0 0.00091 20.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain TPR_11 PF13414.6 GAX12654.1 - 0.00039 20.0 0.9 0.003 17.2 0.0 2.6 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 GAX12654.1 - 0.00086 19.5 0.0 7.5 7.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX12654.1 - 0.0029 18.1 0.8 12 6.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX12654.1 - 0.0056 16.5 0.3 28 4.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX12654.1 - 0.012 16.2 2.0 1.4 9.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX12654.1 - 0.069 13.2 0.3 22 5.4 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat SASP_gamma PF04259.14 GAX12655.1 - 0.11 13.0 2.6 0.14 12.7 0.8 2.1 2 0 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type RRM_1 PF00076.22 GAX12656.1 - 8.9e-20 70.3 0.0 1.9e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX12656.1 - 1.7e-05 24.4 0.0 0.094 12.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 GAX12656.1 - 0.041 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Proteasome PF00227.26 GAX12657.1 - 2.2e-56 190.3 0.0 2.9e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX12657.1 - 7.2e-14 51.2 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Arf PF00025.21 GAX12658.1 - 0.068 12.6 7.4 0.035 13.6 2.0 2.8 3 1 0 3 3 3 0 ADP-ribosylation factor family DGF-1_C PF11040.8 GAX12658.1 - 1.5 8.9 9.3 0.28 11.2 0.4 3.7 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF842 PF05811.13 GAX12659.1 - 2e-29 101.9 6.1 2.5e-29 101.6 6.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) HU-CCDC81_bac_2 PF18175.1 GAX12659.1 - 0.052 13.4 0.2 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 DUF2407_C PF13373.6 GAX12659.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Methyltransf_11 PF08241.12 GAX12660.1 - 9.7e-10 39.0 0.0 1.7e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX12660.1 - 3.9e-06 27.5 0.0 1.6e-05 25.5 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX12660.1 - 6.8e-05 22.3 0.0 9.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAX12660.1 - 0.00031 20.6 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX12660.1 - 0.00044 20.9 0.0 0.00094 19.9 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX12660.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GAX12660.1 - 0.029 12.9 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 GAX12660.1 - 0.049 13.5 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 GAX12660.1 - 0.17 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW JAB PF01398.21 GAX12661.1 - 2.4e-16 59.8 0.0 4.5e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 GAX12661.1 - 0.0031 17.3 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain L_HMGIC_fpl PF10242.9 GAX12662.1 - 0.0058 16.8 5.5 0.0058 16.8 5.5 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF2976 PF11190.8 GAX12662.1 - 0.27 11.1 0.6 0.62 9.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF2593 PF10767.9 GAX12662.1 - 0.37 10.9 4.8 0.57 10.2 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Sporozoite_P67 PF05642.11 GAX12662.1 - 3.1 5.8 3.9 4.4 5.3 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YL1 PF05764.13 GAX12662.1 - 4.9 7.2 10.4 7.7 6.5 10.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PhyH PF05721.13 GAX12664.1 - 3.2e-12 47.2 0.0 5e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3783 PF12646.7 GAX12665.1 - 0.00015 21.7 0.0 0.00049 20.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3783) Ribosomal_L7Ae PF01248.26 GAX12666.1 - 7.3e-23 80.1 0.1 1.1e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2229 PF09989.9 GAX12666.1 - 0.19 11.4 0.3 1.5 8.4 0.0 1.9 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1415 PF07209.12 GAX12667.1 - 5.2e-51 172.8 0.0 8e-51 172.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) MOSC PF03473.17 GAX12668.1 - 1.9e-27 95.8 0.0 6.9e-27 94.0 0.0 1.8 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 GAX12668.1 - 5.7e-16 58.5 0.0 9.9e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain LSM PF01423.22 GAX12669.1 - 1.6e-18 66.2 0.0 1.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Glyoxalase_4 PF13669.6 GAX12670.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NAD_binding_10 PF13460.6 GAX12671.1 - 4.5e-25 88.6 0.0 5.6e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAX12671.1 - 3.9e-08 33.1 0.0 1.2e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAX12671.1 - 8.9e-06 25.4 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 GAX12671.1 - 0.00017 20.9 0.1 0.0048 16.1 0.1 2.7 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 GAX12671.1 - 0.00019 21.9 0.1 0.00047 20.6 0.1 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAX12671.1 - 0.00026 20.5 0.0 0.0021 17.5 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 GAX12671.1 - 0.0021 18.3 0.1 0.004 17.4 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAX12671.1 - 0.0024 17.9 0.0 0.009 16.1 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAX12671.1 - 0.004 16.6 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAX12671.1 - 0.0084 15.3 0.0 0.072 12.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 GAX12671.1 - 0.034 14.3 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAX12671.1 - 0.035 14.7 0.0 0.097 13.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sigma54_activ_2 PF14532.6 GAX12671.1 - 0.074 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DDE_3 PF13358.6 GAX12673.1 - 0.0022 17.8 0.0 0.0047 16.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease C1_2 PF03107.16 GAX12673.1 - 0.8 10.1 9.0 0.092 13.1 4.0 2.1 2 0 0 2 2 2 0 C1 domain EamA PF00892.20 GAX12674.1 - 1.5e-12 47.9 28.0 2.4e-06 27.8 8.2 3.2 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 GAX12674.1 - 0.0024 17.2 0.4 0.0024 17.2 0.4 2.7 2 2 1 3 3 3 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 GAX12674.1 - 0.022 14.5 4.0 0.11 12.3 4.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) Herpes_UL52 PF03121.15 GAX12675.1 - 1.5e-08 34.4 0.1 2.9e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Adhesin_P1 PF03257.13 GAX12675.1 - 0.045 14.3 1.2 0.27 11.8 0.9 2.2 2 0 0 2 2 2 0 Mycoplasma adhesin P1 DUF285 PF03382.14 GAX12678.1 - 2.5e-58 195.1 33.0 2.7e-30 104.6 10.0 2.3 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 CBFD_NFYB_HMF PF00808.23 GAX12678.1 - 6.2e-10 39.2 0.3 1.4e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX12678.1 - 5.7e-07 30.0 0.0 5.7e-07 30.0 0.0 2.6 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SDA1 PF05285.12 GAX12678.1 - 0.14 11.5 27.1 0.19 11.1 27.1 1.2 1 0 0 1 1 1 0 SDA1 ALMT PF11744.8 GAX12678.1 - 0.28 10.0 4.8 0.39 9.5 4.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 GAX12678.1 - 0.54 9.4 3.7 0.85 8.8 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 GAX12678.1 - 2.2 7.2 9.2 3.7 6.4 9.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2457 PF10446.9 GAX12678.1 - 2.8 7.0 27.9 5.1 6.1 27.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RR_TM4-6 PF06459.12 GAX12678.1 - 5.3 6.8 15.9 8.9 6.0 15.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hemerythrin PF01814.23 GAX12679.1 - 8.8e-05 23.1 0.1 0.00016 22.3 0.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_GPO PF05929.11 GAX12679.1 - 0.14 11.8 0.6 0.22 11.1 0.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF285 PF03382.14 GAX12681.1 - 1.8e-90 298.9 33.7 2.8e-34 117.5 8.2 3.2 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 Terpene_synth_C PF03936.16 GAX12681.1 - 0.11 11.9 2.1 3.9 6.7 0.0 3.9 3 2 4 7 7 7 0 Terpene synthase family, metal binding domain DAAD PF18752.1 GAX12682.1 - 0.33 10.8 7.5 0.38 10.6 7.5 1.0 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase ubiquitin PF00240.23 GAX12683.1 - 5.7e-34 115.7 0.4 7.4e-34 115.3 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GAX12683.1 - 7.1e-29 99.5 10.6 1.1e-28 98.9 10.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GAX12683.1 - 2.5e-16 59.3 0.7 3.3e-16 58.9 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX12683.1 - 1.3e-05 25.6 0.1 5.1e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX12683.1 - 0.0028 17.5 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX12683.1 - 0.0079 16.3 0.0 0.017 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAX12683.1 - 0.012 16.0 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 GAX12683.1 - 0.034 14.7 0.0 0.041 14.4 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX12683.1 - 0.062 13.4 1.7 6.6 6.8 0.0 2.4 3 0 0 3 3 3 0 Ubiquitin-like domain DUF2031 PF09592.10 GAX12684.1 - 0.052 13.1 0.3 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF2828 PF11443.8 GAX12684.1 - 0.094 10.8 5.2 0.12 10.4 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Use1 PF09753.9 GAX12684.1 - 0.16 11.7 12.6 0.36 10.5 12.6 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 RR_TM4-6 PF06459.12 GAX12684.1 - 1.5 8.5 11.7 2.6 7.8 11.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dsh_C PF12316.8 GAX12684.1 - 3 8.2 6.2 4.9 7.5 6.2 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal AA_kinase PF00696.28 GAX12685.1 - 1.1e-48 166.0 0.1 1.9e-48 165.2 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 GAX12685.1 - 7.8e-10 38.4 0.1 4.8e-05 23.0 0.0 2.9 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 GAX12685.1 - 0.00023 20.9 0.4 0.015 15.1 0.1 2.6 2 0 0 2 2 2 1 ACT domain Mito_carr PF00153.27 GAX12686.1 - 3.4e-43 145.5 3.2 2.2e-17 62.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ResB PF05140.14 GAX12686.1 - 0.061 12.0 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 ResB-like family MPC PF03650.13 GAX12687.1 - 1.5e-43 147.4 1.3 1.3e-24 86.5 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial pyruvate carriers TatD_DNase PF01026.21 GAX12688.1 - 2.9e-44 151.4 0.0 3.3e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase LMBR1 PF04791.16 GAX12689.1 - 4.4e-55 187.6 23.1 1.5e-36 126.4 0.2 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein Peptidase_S10 PF00450.22 GAX12690.1 - 1.5e-93 314.5 0.0 2e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3404 PF11884.8 GAX12690.1 - 0.07 12.3 0.4 2.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3404) RCR PF12273.8 GAX12690.1 - 4.7 7.9 5.1 1.7 9.3 2.0 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red RdRP PF05183.12 GAX12691.1 - 2.1e-31 109.2 0.0 2.7e-15 56.1 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase Steroid_dh PF02544.16 GAX12692.1 - 3.3e-41 140.8 2.8 3.3e-41 140.8 2.8 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 GAX12692.1 - 8.1e-06 25.5 1.5 1.3e-05 24.8 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 GAX12692.1 - 9.6e-05 22.7 0.7 9.6e-05 22.7 0.7 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 GAX12692.1 - 0.024 15.1 0.1 0.062 13.7 0.1 1.7 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Mltc_N PF11873.8 GAX12693.1 - 0.0093 15.7 0.4 0.015 15.0 0.4 1.2 1 0 0 1 1 1 1 Membrane-bound lytic murein transglycosylase C, N-terminal domain LapA_dom PF06305.11 GAX12693.1 - 1.4 8.8 3.8 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF1325 PF07039.11 GAX12695.1 - 9e-27 93.8 0.0 1.2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain SAP30_Sin3_bdg PF13867.6 GAX12695.1 - 1.8e-07 31.4 0.0 3.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 HSF_DNA-bind PF00447.17 GAX12696.1 - 4.7e-14 52.8 0.1 7.2e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding AAA_16 PF13191.6 GAX12697.1 - 1.2e-20 74.6 0.1 3.7e-20 73.0 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX12697.1 - 7.4e-05 23.0 0.6 0.072 13.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 GAX12697.1 - 0.034 13.5 0.3 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 GAX12697.1 - 0.053 13.4 0.1 0.14 12.1 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 GAX12697.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX12697.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PDZ_6 PF17820.1 GAX12698.1 - 1.3e-08 34.5 0.2 2.7e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 PDZ domain zf-RING_UBOX PF13445.6 GAX12698.1 - 2.3e-06 27.5 3.9 2.3e-06 27.5 3.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger PDZ_2 PF13180.6 GAX12698.1 - 4e-05 23.9 0.0 7.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain zf-RING_4 PF14570.6 GAX12698.1 - 0.00047 19.9 11.0 0.0021 17.8 11.0 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GAX12698.1 - 0.00067 19.9 12.5 0.0021 18.4 12.5 1.9 1 1 0 1 1 1 1 Ring finger domain PDZ PF00595.24 GAX12698.1 - 0.0015 18.9 0.1 0.0028 18.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain zf-C3HC4 PF00097.25 GAX12698.1 - 0.0067 16.3 10.4 0.017 15.0 10.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tricorn_PDZ PF14685.6 GAX12698.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain zf-RING_5 PF14634.6 GAX12698.1 - 0.11 12.5 11.7 0.27 11.2 11.7 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAX12698.1 - 0.13 12.4 13.2 2.1 8.6 13.2 2.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PDZ_1 PF12812.7 GAX12698.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 PDZ-like domain zf-4CXXC_R1 PF10497.9 GAX12698.1 - 0.44 10.8 6.5 1.2 9.4 6.5 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_3 PF13920.6 GAX12698.1 - 1.1 9.1 15.3 14 5.6 15.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX12698.1 - 6.7 7.0 14.3 4.1 7.6 11.9 2.0 2 1 0 2 2 2 0 FANCL C-terminal domain DIM1 PF02966.16 GAX12699.1 - 6.3e-67 223.4 0.4 7.1e-67 223.2 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 GlcNAc-1_reg PF18440.1 GAX12699.1 - 0.06 13.6 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF3192 PF11399.8 GAX12699.1 - 0.11 12.4 0.2 0.15 12.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) SF3b10 PF07189.11 GAX12700.1 - 2.3e-33 114.1 0.0 3.3e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Ribosomal_S8 PF00410.19 GAX12701.1 - 8.7e-05 22.5 0.0 9.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L35Ae PF01247.18 GAX12702.1 - 1.8e-35 121.0 0.1 2e-35 120.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae CTP_synth_N PF06418.14 GAX12703.1 - 1.4e-118 395.1 0.0 1.8e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 GAX12703.1 - 9.3e-51 172.3 0.0 1.3e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAX12703.1 - 0.00025 20.9 0.1 0.00088 19.1 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 GAX12703.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 GAX12703.1 - 0.046 12.7 1.7 0.099 11.6 0.8 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CopG_antitoxin PF12441.8 GAX12703.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system LMBR1 PF04791.16 GAX12705.1 - 4.6e-56 190.8 19.7 3.3e-54 184.7 19.7 2.0 1 1 0 1 1 1 1 LMBR1-like membrane protein PsbJ PF01788.17 GAX12705.1 - 2.9 7.8 8.2 0.12 12.2 0.9 2.6 2 0 0 2 2 2 0 PsbJ FAD_binding_2 PF00890.24 GAX12706.1 - 1.2e-72 245.4 3.1 1.6e-72 244.9 3.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAX12706.1 - 4.9e-06 26.6 0.5 1.5e-05 24.9 0.1 2.0 2 1 0 2 2 2 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 GAX12706.1 - 0.00013 21.3 0.2 0.13 11.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX12706.1 - 0.0098 15.0 0.3 0.65 9.0 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 GAX12706.1 - 0.03 13.9 1.9 0.1 12.2 1.5 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Glyco_hydro_1 PF00232.18 GAX12707.1 - 8.4e-117 390.3 0.0 9.3e-117 390.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 MAPEG PF01124.18 GAX12708.1 - 1.2e-12 47.9 0.1 1.7e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 MAPEG family UcrQ PF02939.16 GAX12708.1 - 0.12 12.3 0.4 0.8 9.7 0.0 2.3 2 1 0 2 2 2 0 UcrQ family ABC1 PF03109.16 GAX12709.1 - 3.9e-27 94.8 0.1 1.1e-26 93.3 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 GAX12709.1 - 3.6e-06 27.1 0.0 1.3e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX12709.1 - 8.3e-05 22.1 0.0 0.011 15.1 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain PriC PF07445.12 GAX12709.1 - 0.19 11.6 1.3 0.38 10.7 0.4 2.0 2 0 0 2 2 2 0 Primosomal replication protein priC FliG_N PF14842.6 GAX12709.1 - 0.61 10.6 2.9 19 5.8 0.1 3.4 3 0 0 3 3 3 0 FliG N-terminal domain bZIP_2 PF07716.15 GAX12709.1 - 5.5 7.2 5.7 10 6.3 0.6 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Baculo_PEP_C PF04513.12 GAX12709.1 - 8.9 6.3 10.1 0.38 10.8 3.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 GAX12711.1 - 7.5e-40 137.0 0.0 1.5e-39 135.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12711.1 - 2e-28 99.4 0.0 3.5e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ArfGap PF01412.18 GAX12714.1 - 2.3e-32 111.5 0.0 3e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BTB PF00651.31 GAX12715.1 - 0.041 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain COPI_assoc PF08507.10 GAX12716.1 - 8.6e-10 38.8 7.4 1e-09 38.5 7.4 1.1 1 0 0 1 1 1 1 COPI associated protein pKID PF02173.17 GAX12716.1 - 0.041 13.3 0.4 0.075 12.5 0.4 1.3 1 0 0 1 1 1 0 pKID domain DUF2232 PF09991.9 GAX12716.1 - 0.048 12.8 11.0 0.062 12.5 11.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Zn_Tnp_IS1595 PF12760.7 GAX12717.1 - 0.012 15.6 0.5 0.56 10.2 0.1 2.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.19 GAX12717.1 - 0.13 12.3 0.2 0.47 10.5 0.3 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin PF00301.20 GAX12717.1 - 0.24 11.5 3.7 4 7.6 3.7 2.3 1 1 0 1 1 1 0 Rubredoxin Rubredoxin_2 PF18073.1 GAX12717.1 - 0.93 9.3 4.2 12 5.7 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DNA_RNApol_7kD PF03604.13 GAX12717.1 - 1.7 8.4 4.4 12 5.7 4.4 2.2 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 GAX12717.1 - 2.4 8.3 4.2 9.8 6.4 4.3 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 GAX12718.1 - 1.8e-07 30.9 15.6 3.1e-07 30.1 15.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX12718.1 - 0.00012 21.9 13.6 0.00025 20.8 13.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TPR_MLP1_2 PF07926.12 GAX12718.1 - 0.0017 18.4 11.1 0.0017 18.4 11.1 7.4 5 1 2 7 7 7 3 TPR/MLP1/MLP2-like protein zf-RING_5 PF14634.6 GAX12718.1 - 0.0033 17.3 14.3 0.0077 16.2 14.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAX12718.1 - 0.0046 16.8 15.4 0.0046 16.8 15.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX12718.1 - 0.0053 17.1 15.8 0.011 16.0 15.8 1.6 1 0 0 1 1 1 1 Ring finger domain PKcGMP_CC PF16808.5 GAX12718.1 - 0.0063 16.3 0.1 0.0063 16.3 0.1 6.6 6 0 0 6 6 6 3 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C3HC4 PF00097.25 GAX12718.1 - 0.053 13.4 17.4 0.11 12.4 17.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VBS PF08913.10 GAX12718.1 - 0.32 11.5 4.7 0.32 11.4 1.6 2.7 2 0 0 2 2 2 0 Vinculin Binding Site DUF2680 PF10925.8 GAX12718.1 - 6.6 6.8 7.2 2.2 8.3 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) PC-Esterase PF13839.6 GAX12719.1 - 4.1e-16 59.6 2.3 2.6e-09 37.3 1.9 2.4 1 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SBP PF03110.14 GAX12720.1 - 4.2 7.8 6.8 0.35 11.2 1.1 2.1 2 0 0 2 2 2 0 SBP domain TFIIA PF03153.13 GAX12721.1 - 3.5 7.5 26.5 5.1 7.0 26.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPT PF03151.16 GAX12722.1 - 1.2e-23 83.9 13.0 2.1e-23 83.1 13.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX12722.1 - 0.025 14.8 32.9 0.52 10.5 12.4 2.7 1 1 2 3 3 3 0 EamA-like transporter family zf-MYND PF01753.18 GAX12723.1 - 4.4e-08 33.1 36.3 8.3e-07 29.0 15.3 3.0 2 1 0 2 2 2 2 MYND finger zf-CCHC_5 PF14787.6 GAX12723.1 - 0.62 9.8 0.0 0.62 9.8 0.0 2.9 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger SNARE_assoc PF09335.11 GAX12724.1 - 1.8e-23 83.3 9.1 3.6e-23 82.3 9.1 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein tRNA-synt_1c PF00749.21 GAX12725.1 - 2.2e-101 338.9 0.0 2.8e-101 338.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAX12725.1 - 2.7e-43 147.9 0.0 1.1e-42 145.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_bind PF01588.20 GAX12725.1 - 1.8e-26 92.1 0.1 3.2e-26 91.3 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Pkinase PF00069.25 GAX12726.1 - 2e-36 125.7 0.0 1.1e-35 123.3 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12726.1 - 1.7e-34 119.3 0.0 5.1e-34 117.7 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX12726.1 - 0.034 13.5 0.0 0.23 10.7 0.0 2.1 2 1 0 2 2 2 0 Kinase-like HSF_DNA-bind PF00447.17 GAX12727.1 - 4.6e-16 59.2 0.0 8.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 GAX12727.1 - 0.013 16.0 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Ets-domain DUF5318 PF17249.2 GAX12727.1 - 0.15 11.8 0.2 0.45 10.3 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5318) Bac_luciferase PF00296.20 GAX12729.1 - 0.083 12.3 0.5 1.6 8.0 0.0 2.6 3 0 0 3 3 3 0 Luciferase-like monooxygenase Ribosom_S30AE_C PF16321.5 GAX12730.1 - 6.6e-21 73.8 0.1 1.4e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 GAX12730.1 - 2.6e-18 66.6 0.1 4.3e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein TnpB_IS66 PF05717.13 GAX12730.1 - 0.066 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 IS66 Orf2 like protein DPPIV_N PF00930.21 GAX12732.1 - 6.9e-61 206.0 0.0 6.9e-59 199.4 0.0 2.5 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAX12732.1 - 4.7e-55 186.4 0.0 6.7e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAX12732.1 - 7.3e-11 42.2 0.1 9.5e-09 35.2 0.1 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 GAX12732.1 - 6.4e-05 22.6 0.0 0.00018 21.1 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 GAX12732.1 - 0.00015 22.5 0.9 0.00015 22.5 0.9 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 GAX12732.1 - 0.0013 18.2 0.4 0.0023 17.5 0.4 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 GAX12732.1 - 0.0046 16.3 0.8 0.034 13.4 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 GAX12732.1 - 0.024 14.0 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_3 PF07859.13 GAX12732.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3141 PF11339.8 GAX12732.1 - 0.046 12.2 0.2 0.066 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Abhydrolase_1 PF00561.20 GAX12732.1 - 0.051 13.2 0.2 0.093 12.4 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 GAX12732.1 - 0.067 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2920 PF11144.8 GAX12732.1 - 0.24 10.5 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PD40 PF07676.12 GAX12732.1 - 1 9.4 4.0 12 5.9 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 GAX12733.1 - 5.3e-06 27.1 3.0 0.01 16.7 0.4 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Utp8 PF10395.9 GAX12733.1 - 0.036 12.6 0.0 0.07 11.6 0.0 1.4 1 1 0 1 1 1 0 Utp8 family Linker_histone PF00538.19 GAX12734.1 - 2.5e-15 56.6 0.8 8e-15 55.0 0.8 2.0 1 0 0 1 1 1 1 linker histone H1 and H5 family WSD PF15613.6 GAX12734.1 - 6.3e-08 33.0 0.0 7.1e-07 29.6 0.0 3.0 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PWWP PF00855.17 GAX12734.1 - 0.0019 18.6 0.0 0.0019 18.6 0.0 3.4 4 1 0 4 4 4 1 PWWP domain Exo5 PF09810.9 GAX12734.1 - 7.2 6.0 8.1 20 4.5 0.6 2.8 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Syntaxin-18_N PF10496.9 GAX12735.1 - 0.2 11.9 2.4 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus SLH PF00395.20 GAX12736.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 S-layer homology domain RRM_1 PF00076.22 GAX12739.1 - 2e-16 59.6 0.0 3.4e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX12739.1 - 8.4e-07 29.0 0.0 2.5e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 GAX12739.1 - 0.059 13.6 0.1 5.6 7.2 0.0 2.4 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Asp_Arg_Hydrox PF05118.15 GAX12740.1 - 2.4e-13 50.2 0.4 6.2e-12 45.6 0.1 2.8 3 0 0 3 3 3 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_14 PF13428.6 GAX12740.1 - 1.7 9.7 3.9 9.5 7.3 0.1 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX12740.1 - 7.8 7.4 6.4 9 7.2 0.2 4.2 5 1 0 5 5 5 0 Tetratricopeptide repeat GYF PF02213.16 GAX12741.1 - 7.4e-13 48.0 1.8 1.3e-12 47.1 1.8 1.4 1 0 0 1 1 1 1 GYF domain Wbp11 PF09429.10 GAX12741.1 - 3.8e-09 36.8 16.5 3.8e-09 36.8 16.5 3.3 2 1 1 3 3 3 1 WW domain binding protein 11 GYF_2 PF14237.6 GAX12741.1 - 2.2e-07 30.6 0.9 5e-07 29.4 0.9 1.6 1 0 0 1 1 1 1 GYF domain 2 NpwBP PF12622.7 GAX12741.1 - 0.003 18.3 27.6 0.011 16.4 22.7 3.8 2 1 0 2 2 2 1 mRNA biogenesis factor DUF5398 PF17376.2 GAX12741.1 - 1.7 9.3 8.8 6.6 7.4 0.0 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5398) DUF4435 PF14491.6 GAX12741.1 - 2.1 8.2 7.4 11 5.8 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4435) LRR_4 PF12799.7 GAX12742.1 - 0.00016 22.0 5.5 0.82 10.2 0.1 4.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX12742.1 - 0.19 11.5 2.9 1.3 8.9 0.5 3.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 GAX12742.1 - 1.5 9.7 3.5 1.5e+02 3.6 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 GAX12743.1 - 7.6e-16 57.6 33.3 6.3e-06 25.9 5.6 4.2 3 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 GAX12743.1 - 4.7e-15 55.4 26.4 0.0003 21.1 0.6 6.4 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 GAX12743.1 - 0.0011 19.0 11.8 0.0021 18.1 11.8 1.5 1 0 0 1 1 1 1 MYND finger DUF1772 PF08592.11 GAX12743.1 - 0.037 14.3 0.0 7.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) LRR_1 PF00560.33 GAX12743.1 - 2.5 9.0 20.2 61 4.8 0.0 8.1 8 1 0 8 8 8 0 Leucine Rich Repeat CBM_14 PF01607.24 GAX12746.1 - 1.3e-06 28.4 5.6 1.3e-06 28.4 5.6 3.2 2 1 1 3 3 3 1 Chitin binding Peritrophin-A domain VTC PF09359.10 GAX12747.1 - 1.4e-71 241.2 1.2 1.4e-71 241.2 1.2 1.9 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 GAX12747.1 - 2.7e-11 43.7 1.4 2.7e-11 43.7 1.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAX12747.1 - 1.2e-07 32.0 8.9 0.00067 19.7 2.8 3.3 1 1 2 3 3 3 3 SPX domain LemA PF04011.12 GAX12747.1 - 0.22 11.4 2.2 0.18 11.6 0.3 1.8 2 0 0 2 2 2 0 LemA family C_Hendra PF16821.5 GAX12747.1 - 0.82 9.5 5.4 0.1 12.5 0.5 1.8 2 0 0 2 2 2 0 C protein from hendra and measles viruses Ribosomal_S6e PF01092.19 GAX12748.1 - 7.7e-49 164.8 0.9 1.8e-48 163.7 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e LSM PF01423.22 GAX12749.1 - 2e-18 65.8 0.6 2.5e-18 65.5 0.6 1.1 1 0 0 1 1 1 1 LSM domain Mito_carr PF00153.27 GAX12750.1 - 1.7e-43 146.4 4.8 4.9e-20 71.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_3 PF07859.13 GAX12750.1 - 0.0096 15.8 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3043 PF11241.8 GAX12751.1 - 0.0081 16.2 1.2 0.017 15.1 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3043) Ank_2 PF12796.7 GAX12752.1 - 7.8e-40 135.3 3.7 1.3e-07 32.1 0.2 9.5 3 1 7 11 11 11 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX12752.1 - 3.9e-28 94.4 19.4 0.28 11.9 0.0 15.7 16 0 0 16 16 16 10 Ankyrin repeat Ank PF00023.30 GAX12752.1 - 9.5e-26 89.1 27.9 0.35 11.4 0.0 15.6 15 1 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.6 GAX12752.1 - 2.6e-24 85.0 20.7 0.0083 16.4 0.0 13.6 10 3 5 15 15 15 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX12752.1 - 1.9e-23 82.5 13.9 0.0077 16.8 0.3 12.6 10 3 3 13 13 13 8 Ankyrin repeats (many copies) DUF572 PF04502.13 GAX12753.1 - 3.2e-60 204.5 12.5 5.3e-60 203.8 12.5 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) Taq-exonuc PF09281.10 GAX12753.1 - 1.1 9.2 4.7 0.75 9.8 0.1 2.3 2 0 0 2 2 2 0 Taq polymerase, exonuclease DUF285 PF03382.14 GAX12754.1 - 3.2e-93 307.8 50.9 4.3e-36 123.3 10.4 3.3 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 DrrA_P4M PF14860.6 GAX12754.1 - 0.036 13.9 5.4 39 4.2 0.1 5.0 2 1 4 6 6 6 0 DrrA phosphatidylinositol 4-phosphate binding domain E7R PF17467.2 GAX12754.1 - 0.16 12.1 5.7 1.2 9.3 0.0 4.3 3 2 2 5 5 5 0 Viral Protein E7 HEAT PF02985.22 GAX12755.1 - 7.8e-15 53.7 10.5 0.067 13.5 0.2 7.6 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 GAX12755.1 - 3.6e-08 33.7 13.9 0.0078 16.6 1.0 7.0 6 1 1 7 7 7 2 HEAT repeats PDZ_6 PF17820.1 GAX12755.1 - 2.1e-07 30.7 0.0 5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain CLASP_N PF12348.8 GAX12755.1 - 2e-06 27.6 0.1 0.024 14.2 0.0 4.6 6 0 0 6 6 6 2 CLASP N terminal Cnd1 PF12717.7 GAX12755.1 - 8.7e-06 25.9 0.6 0.99 9.4 0.0 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX12755.1 - 0.00012 22.5 12.7 0.34 11.5 0.3 6.3 5 1 1 6 6 6 2 HEAT-like repeat Arm PF00514.23 GAX12755.1 - 0.00019 21.4 3.0 3.8 7.7 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat PDZ_2 PF13180.6 GAX12755.1 - 0.00032 21.0 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX12755.1 - 0.00059 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DNA_alkylation PF08713.11 GAX12755.1 - 0.041 13.6 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 DNA alkylation repair enzyme BSD PF03909.17 GAX12756.1 - 2.5e-11 43.4 2.0 1.1e-07 31.7 0.7 3.4 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 GAX12756.1 - 2.1e-08 34.4 0.4 4.1e-08 33.4 0.4 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DnaJ PF00226.31 GAX12757.1 - 1.2e-20 73.4 1.4 2e-20 72.6 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain TrmO PF01980.16 GAX12758.1 - 3.9e-36 123.9 0.0 7.6e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 GAX12758.1 - 0.03 14.4 0.0 0.072 13.2 0.0 1.7 1 1 0 1 1 1 0 TrmO C-terminal domain DUF2407_C PF13373.6 GAX12759.1 - 0.58 10.3 2.2 30 4.8 1.1 2.7 2 1 0 2 2 2 0 DUF2407 C-terminal domain WLM PF08325.10 GAX12760.1 - 7.1e-32 111.0 2.2 5.4e-31 108.2 2.2 2.1 1 1 0 1 1 1 1 WLM domain ubiquitin PF00240.23 GAX12760.1 - 4.4e-05 23.1 0.0 8.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GAX12760.1 - 0.0061 17.1 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PB1 PF00564.24 GAX12760.1 - 0.014 15.4 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 PB1 domain TUG-UBL1 PF11470.8 GAX12760.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 TUG ubiquitin-like domain TnpV PF14198.6 GAX12760.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpV PTEN_C2 PF10409.9 GAX12763.1 - 9e-20 70.8 0.0 2.3e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein AMH_N PF04709.12 GAX12763.1 - 0.068 12.1 0.2 2.3 7.0 0.2 2.4 2 0 0 2 2 2 0 Anti-Mullerian hormone, N terminal region Y_phosphatase PF00102.27 GAX12763.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAX12763.1 - 0.17 12.0 1.8 0.53 10.4 0.0 2.5 3 0 0 3 3 3 0 Inositol hexakisphosphate DSPc PF00782.20 GAX12763.1 - 0.19 11.6 0.1 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain MPP6 PF10175.9 GAX12764.1 - 0.22 12.0 0.1 0.22 12.0 0.1 3.3 3 1 0 3 3 3 0 M-phase phosphoprotein 6 Nuc_sug_transp PF04142.15 GAX12767.1 - 8.7e-26 90.8 11.7 1.1e-25 90.4 11.7 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAX12767.1 - 0.027 14.7 27.1 0.15 12.2 9.2 2.5 2 1 0 2 2 2 0 EamA-like transporter family Nuc_sug_transp PF04142.15 GAX12768.1 - 9.6e-30 103.8 12.6 1.5e-29 103.2 12.6 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAX12768.1 - 2.1e-05 24.7 10.9 2.1e-05 24.7 10.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family Phage_holin_5_2 PF16079.5 GAX12768.1 - 3.2 8.1 6.6 5 7.5 3.4 2.9 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V PT PF04886.12 GAX12769.1 - 0.0063 16.0 69.9 0.0071 15.9 31.4 16.9 8 4 4 12 12 12 7 PT repeat Mito_carr PF00153.27 GAX12770.1 - 3.4e-40 135.9 0.5 5.4e-18 64.7 0.0 3.2 1 1 2 3 3 3 3 Mitochondrial carrier protein HSP90 PF00183.18 GAX12772.1 - 1.9e-176 588.0 18.7 3.5e-176 587.1 18.7 1.4 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 GAX12772.1 - 1.1e-10 41.5 0.1 2.8e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAX12772.1 - 4.3e-10 40.1 0.0 9e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Secretin_N PF03958.17 GAX12772.1 - 0.0096 16.3 0.0 0.04 14.3 0.0 2.0 1 0 0 1 1 1 1 Bacterial type II/III secretion system short domain DUF3523 PF12037.8 GAX12774.1 - 3 7.1 4.7 4.7 6.5 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) CRM1_C PF08767.11 GAX12775.1 - 1.6e-118 395.5 3.5 2.4e-117 391.7 0.7 2.4 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 GAX12775.1 - 2.3e-36 125.1 2.7 1.4e-35 122.5 2.7 2.5 1 0 0 1 1 1 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAX12775.1 - 1.4e-30 104.7 0.3 3.2e-30 103.6 0.3 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GAX12775.1 - 4.5e-30 103.5 0.9 4.5e-30 103.5 0.9 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 GAX12775.1 - 3.3e-15 55.3 0.2 8.7e-15 53.9 0.2 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 GAX12775.1 - 7.5e-13 48.2 0.7 4.2e-12 45.8 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Symplekin_C PF12295.8 GAX12775.1 - 0.035 14.2 0.9 2.5 8.2 0.0 3.5 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal DUF3385 PF11865.8 GAX12775.1 - 0.054 13.4 0.1 0.73 9.7 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) GDP_Man_Dehyd PF16363.5 GAX12776.1 - 8.4e-57 193.0 0.0 1.6e-56 192.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX12776.1 - 1.3e-47 162.3 0.0 1.8e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX12776.1 - 2.3e-11 43.2 0.0 3.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX12776.1 - 2.5e-10 40.0 0.0 1.8e-05 24.0 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 GAX12776.1 - 2.7e-08 33.3 0.1 7.4e-07 28.6 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX12776.1 - 7.6e-07 28.5 0.0 1.9e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAX12776.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GAX12776.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding zinc_ribbon_10 PF10058.9 GAX12777.1 - 0.017 14.8 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 GAX12777.1 - 0.088 12.8 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Phytochelatin PF05023.14 GAX12778.1 - 1.6e-41 141.9 0.0 1.6e-41 141.9 0.0 2.6 2 1 1 3 3 3 1 Phytochelatin synthase DivIVA PF05103.13 GAX12778.1 - 1.3 9.1 3.8 3.4 7.8 3.8 1.6 1 0 0 1 1 1 0 DivIVA protein Complex1_LYR PF05347.15 GAX12779.1 - 5.6e-12 45.5 0.0 1.3e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAX12779.1 - 0.0021 18.8 0.2 0.0025 18.5 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like CRS1_YhbY PF01985.21 GAX12780.1 - 6.5e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Gal-bind_lectin PF00337.22 GAX12780.1 - 0.027 14.0 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Galactoside-binding lectin Arf PF00025.21 GAX12781.1 - 3e-11 43.1 0.1 1.2e-06 28.1 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 GAX12781.1 - 1.6e-07 31.6 0.1 0.0058 16.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAX12781.1 - 2.1e-06 27.2 0.0 0.03 13.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 GAX12781.1 - 3.4e-05 24.3 0.0 0.00011 22.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 GAX12781.1 - 0.0006 20.0 0.1 0.0014 18.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 GAX12781.1 - 0.00068 19.3 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.27 GAX12781.1 - 0.0017 18.9 0.0 0.013 16.0 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 GAX12781.1 - 0.0019 18.4 0.2 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAX12781.1 - 0.002 18.2 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 GAX12781.1 - 0.009 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_7 PF12775.7 GAX12781.1 - 0.01 15.3 0.1 0.16 11.5 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 GAX12781.1 - 0.033 13.5 0.3 0.13 11.5 0.4 1.9 1 1 1 2 2 2 0 Septin AAA_29 PF13555.6 GAX12781.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 GAX12781.1 - 0.052 13.6 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 GAX12781.1 - 0.053 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.14 GAX12781.1 - 0.09 12.7 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MCM PF00493.23 GAX12781.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain RsgA_GTPase PF03193.16 GAX12781.1 - 0.11 12.4 0.2 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 GAX12781.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 GAX12781.1 - 0.23 10.8 0.1 9.5 5.5 0.0 2.6 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region Nefa_Nip30_N PF10187.9 GAX12781.1 - 0.56 10.6 6.2 0.18 12.1 0.8 2.3 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 HWE_HK PF07536.14 GAX12782.1 - 6.4 7.6 7.0 25 5.6 0.8 3.0 2 1 0 2 2 2 0 HWE histidine kinase Glyco_hydro_125 PF06824.11 GAX12783.1 - 1.1e-119 400.0 0.0 1.5e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) UPF0020 PF01170.18 GAX12784.1 - 4.4e-30 104.9 0.0 6.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 GAX12784.1 - 0.0029 17.4 0.0 1.9 8.2 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain N6_N4_Mtase PF01555.18 GAX12784.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Cons_hypoth95 PF03602.15 GAX12784.1 - 0.21 11.2 0.1 0.45 10.1 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TPD PF14811.6 GAX12785.1 - 9.5e-14 51.4 0.2 4.8e-13 49.2 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function TPD sequence-motif Ank_2 PF12796.7 GAX12786.1 - 1.6e-20 73.5 0.1 1.2e-07 32.2 0.2 5.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX12786.1 - 1.5e-11 44.5 0.2 0.0021 18.6 0.0 5.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX12786.1 - 3.9e-09 36.0 0.8 7 7.6 0.0 8.0 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 GAX12786.1 - 5.1e-08 33.0 1.0 3.7 8.0 0.0 5.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX12786.1 - 0.00028 21.2 1.3 21 5.8 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat BTB PF00651.31 GAX12786.1 - 0.0016 18.6 0.4 0.0042 17.3 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain Nucleocap_ssRNA PF11128.8 GAX12786.1 - 0.18 11.5 0.1 0.55 9.9 0.0 1.7 2 0 0 2 2 2 0 Plant viral coat protein nucleocapsid Ank_2 PF12796.7 GAX12787.1 - 3.4e-26 91.6 0.6 2.9e-13 50.2 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) ACBP PF00887.19 GAX12787.1 - 6.4e-19 68.0 0.4 1.4e-18 66.9 0.4 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 GAX12787.1 - 4.6e-15 55.8 0.2 2.1e-06 28.2 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX12787.1 - 6.2e-15 55.1 0.1 3.5e-10 39.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX12787.1 - 1.1e-11 43.8 0.0 0.0027 18.1 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX12787.1 - 2.2e-11 43.7 0.7 0.0025 18.2 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat DUF4381 PF14316.6 GAX12787.1 - 0.2 11.9 3.5 0.24 11.6 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) PI-PLC-X PF00388.19 GAX12788.1 - 1.7e-50 170.4 0.0 3.9e-50 169.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAX12788.1 - 4.3e-37 127.0 0.6 1.2e-36 125.5 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 GAX12788.1 - 3.7e-08 33.6 0.0 1.4e-07 31.7 0.0 2.1 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 GAX12788.1 - 0.0087 15.5 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAX12788.1 - 0.063 13.7 0.0 0.43 11.1 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 GAX12788.1 - 0.1 12.6 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Fer2 PF00111.27 GAX12790.1 - 0.00074 19.4 0.1 0.0015 18.4 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pkinase PF00069.25 GAX12791.1 - 1.1e-54 185.6 0.0 1.7e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX12791.1 - 3.1e-32 110.5 0.0 2.7e-18 65.8 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX12791.1 - 1.8e-22 79.9 0.0 3.5e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX12791.1 - 3.5e-14 53.0 3.7 4.6e-09 36.6 1.7 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX12791.1 - 5.7e-14 50.5 3.2 0.0002 20.7 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 GAX12791.1 - 4.7e-12 44.8 2.0 0.024 14.5 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 GAX12791.1 - 3.4e-09 36.4 2.8 0.00075 19.3 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX12791.1 - 9.1e-07 28.1 3.8 0.00033 20.0 0.3 3.1 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 GAX12791.1 - 1.4e-05 24.6 0.1 5.5e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX12791.1 - 1.7e-05 24.3 0.0 0.00012 21.5 0.0 2.4 3 1 0 3 3 3 1 Kinase-like APH PF01636.23 GAX12791.1 - 0.0028 17.6 0.1 0.0064 16.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_4 PF12763.7 GAX12791.1 - 0.033 14.1 1.9 2.9 7.9 0.2 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAX12791.1 - 0.16 12.3 0.2 1.4 9.3 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region zf-MYND PF01753.18 GAX12792.1 - 0.00029 20.9 23.1 0.00029 20.9 23.1 2.5 2 0 0 2 2 2 1 MYND finger DUF5462 PF17547.2 GAX12792.1 - 0.024 14.0 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5462) Flavodoxin_1 PF00258.25 GAX12793.1 - 2.4e-08 34.3 0.0 4.1e-08 33.5 0.0 1.2 1 1 0 1 1 1 1 Flavodoxin Shikimate_DH PF01488.20 GAX12793.1 - 0.14 12.2 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 GAX12794.1 - 1.4e-41 142.6 0.0 2.1e-28 99.4 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12794.1 - 8.5e-24 84.2 0.0 2e-08 33.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase FTA2 PF13095.6 GAX12794.1 - 0.04 13.5 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAX12794.1 - 0.043 13.2 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX12794.1 - 0.086 12.8 1.9 0.15 11.9 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 GAX12795.1 - 9.6e-55 184.6 0.0 1.3e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX12795.1 - 1.3e-28 99.7 0.0 2.9e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX12795.1 - 1e-11 44.6 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX12795.1 - 0.00047 19.8 0.0 0.0011 18.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAX12795.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAX12795.1 - 0.0062 16.5 0.4 0.55 10.1 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 GAX12795.1 - 0.035 13.9 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 GAX12795.1 - 0.042 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 GAX12795.1 - 0.045 13.8 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX12795.1 - 0.05 14.0 0.0 0.067 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 GAX12795.1 - 0.076 12.7 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.10 GAX12795.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAX12795.1 - 0.093 11.9 0.0 0.37 9.9 0.0 1.9 2 1 1 3 3 3 0 G-protein alpha subunit Sugar_tr PF00083.24 GAX12796.1 - 2.1e-83 280.7 30.8 2.7e-83 280.4 30.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX12796.1 - 2.4e-25 89.2 43.2 5.9e-24 84.7 33.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2407_C PF13373.6 GAX12796.1 - 8.7 6.5 10.2 12 6.0 2.6 2.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain Pyr_redox_2 PF07992.14 GAX12798.1 - 4.8e-53 180.3 2.3 6.1e-53 180.0 2.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX12798.1 - 2e-18 66.7 1.7 8.1e-14 51.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX12798.1 - 2.2e-11 43.6 2.4 2.1e-07 30.5 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX12798.1 - 5.9e-11 42.1 11.8 0.0013 17.9 2.8 3.4 2 2 0 3 3 3 3 Glucose inhibited division protein A DAO PF01266.24 GAX12798.1 - 1e-07 31.9 10.5 0.0038 16.9 0.7 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.17 GAX12798.1 - 5.5e-07 29.1 0.7 2.5e-06 26.9 0.3 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 GAX12798.1 - 1.1e-06 28.3 3.5 0.00036 20.0 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GAX12798.1 - 2.4e-05 24.7 0.2 0.00055 20.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 GAX12798.1 - 3.1e-05 24.1 5.5 0.0023 18.1 0.6 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAX12798.1 - 3.6e-05 22.8 4.1 0.00018 20.5 0.3 2.5 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox_dim PF02852.22 GAX12798.1 - 4.9e-05 23.6 1.3 0.00016 21.9 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_binding_3 PF01494.19 GAX12798.1 - 5.1e-05 22.7 1.7 0.19 11.0 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 GAX12798.1 - 9.7e-05 21.6 5.4 0.074 12.1 0.2 2.8 2 1 1 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAX12798.1 - 0.0003 20.0 9.0 0.0081 15.3 0.5 3.7 4 0 0 4 4 4 2 FAD binding domain AlaDh_PNT_C PF01262.21 GAX12798.1 - 0.00064 19.1 2.1 0.59 9.4 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 GAX12798.1 - 0.0014 17.8 1.1 0.033 13.3 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAX12798.1 - 0.0031 16.3 10.3 0.0044 15.8 0.3 3.4 3 1 1 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.18 GAX12798.1 - 0.021 14.7 0.6 0.06 13.2 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 GAX12798.1 - 0.039 13.8 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_Gly3P_dh_N PF01210.23 GAX12798.1 - 0.044 13.7 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 GAX12798.1 - 0.046 14.0 2.6 4.2 7.6 0.0 3.1 3 1 0 3 3 3 0 TrkA-N domain ThiF PF00899.21 GAX12798.1 - 0.21 10.9 0.9 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.6 GAX12798.1 - 4.7 7.2 8.5 3.3 7.7 0.1 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding ECH_1 PF00378.20 GAX12799.1 - 8.9e-38 130.0 0.0 1.2e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX12799.1 - 3.3e-36 125.4 0.0 4.1e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Lipase_GDSL_2 PF13472.6 GAX12800.1 - 2.8e-08 34.4 0.0 1.8e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family FlxA PF14282.6 GAX12800.1 - 8.2 6.5 10.6 2.2 8.3 5.1 2.2 2 0 0 2 2 2 0 FlxA-like protein NmrA PF05368.13 GAX12801.1 - 1.2e-09 38.1 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAX12801.1 - 3.9e-08 33.4 0.0 1.4e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Amidase PF01425.21 GAX12801.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Amidase DUF455 PF04305.14 GAX12801.1 - 0.19 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Epimerase PF01370.21 GAX12801.1 - 0.21 11.0 0.5 2.9 7.3 0.0 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Peptidase_S10 PF00450.22 GAX12802.1 - 7.8e-82 275.9 0.1 1.2e-81 275.3 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase CAF1C_H4-bd PF12265.8 GAX12803.1 - 1.6e-13 50.7 0.0 1.1e-12 48.0 0.0 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAX12803.1 - 1.1e-07 32.4 7.0 0.38 11.7 0.2 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX12803.1 - 1.3e-05 25.4 0.0 0.061 13.6 0.0 3.3 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 GAX12803.1 - 2.3 7.9 5.1 4.3 7.0 5.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGK PF00162.19 GAX12804.1 - 2.4e-155 517.2 0.8 2.9e-155 516.9 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase VASt PF16016.5 GAX12805.1 - 1e-17 64.9 0.0 2.9e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain MIF4G PF02854.19 GAX12806.1 - 2.9e-30 105.5 9.0 5.1e-21 75.3 8.1 3.4 4 0 0 4 4 4 2 MIF4G domain MA3 PF02847.17 GAX12806.1 - 2.4e-08 34.0 0.6 1.8e-07 31.2 0.0 2.8 3 0 0 3 3 3 1 MA3 domain DUF737 PF05300.11 GAX12806.1 - 0.00052 20.4 5.7 0.00052 20.4 5.7 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF737) MAP7 PF05672.11 GAX12806.1 - 0.0047 16.6 23.5 0.0047 16.6 23.5 3.5 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family MA3 PF02847.17 GAX12809.1 - 1.2e-35 121.9 0.5 8.4e-21 74.1 0.1 2.4 2 0 0 2 2 2 2 MA3 domain Proteasome PF00227.26 GAX12810.1 - 8.8e-41 139.5 0.0 1.2e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX12810.1 - 1.1e-12 47.4 0.1 1.1e-12 47.4 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF4268 PF14088.6 GAX12811.1 - 0.065 13.1 0.2 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) PCO_ADO PF07847.12 GAX12812.1 - 8.9e-36 123.2 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO Peptidase_M24 PF00557.24 GAX12813.1 - 1.2e-05 25.2 0.2 1.7e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 ThrE PF06738.12 GAX12813.1 - 0.075 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter Peptidase_M24 PF00557.24 GAX12814.1 - 0.0009 19.0 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AGP PF06376.12 GAX12814.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Arabinogalactan peptide tRNA-synt_2c PF01411.19 GAX12815.1 - 4.1e-206 685.8 0.0 5.1e-206 685.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAX12815.1 - 1.6e-16 60.1 0.0 3.3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAX12815.1 - 2.4e-10 40.9 6.0 5.8e-10 39.7 6.0 1.6 1 0 0 1 1 1 1 DHHA1 domain 3HCDH_RFF PF18321.1 GAX12815.1 - 4.4 7.8 5.1 1.2 9.7 0.6 2.5 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain zf-RING_2 PF13639.6 GAX12816.1 - 9.8e-12 45.0 10.7 2.2e-11 43.9 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX12816.1 - 1.3e-10 40.8 4.1 3e-10 39.6 4.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX12816.1 - 5e-09 35.9 7.2 1.2e-08 34.7 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX12816.1 - 2.1e-08 33.8 10.7 4.6e-08 32.8 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX12816.1 - 2.8e-08 33.9 7.9 7.4e-08 32.6 7.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX12816.1 - 1e-05 25.4 4.1 2.5e-05 24.2 4.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX12816.1 - 0.00039 20.3 10.1 0.00071 19.5 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX12816.1 - 0.0011 18.8 9.1 0.002 17.9 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX12816.1 - 0.0023 18.0 5.1 0.0073 16.3 5.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX12816.1 - 0.0038 16.8 6.5 0.0096 15.5 6.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX12816.1 - 0.0054 16.6 5.9 0.011 15.5 5.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-HC5HC2H_2 PF13832.6 GAX12816.1 - 0.011 15.9 2.3 0.024 14.8 2.3 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF2140 PF09911.9 GAX12816.1 - 0.021 14.4 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) C1_2 PF03107.16 GAX12816.1 - 0.037 14.3 1.7 0.1 13.0 1.7 1.7 1 0 0 1 1 1 0 C1 domain LST1 PF05083.13 GAX12816.1 - 0.047 14.0 0.2 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 LST-1 protein PHD PF00628.29 GAX12816.1 - 0.078 12.9 9.8 0.18 11.7 9.8 1.7 1 0 0 1 1 1 0 PHD-finger Tweety PF04906.13 GAX12816.1 - 0.09 11.4 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Tweety Zf_RING PF16744.5 GAX12816.1 - 0.29 11.3 5.8 0.63 10.2 5.8 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 GAX12816.1 - 0.34 11.1 5.2 0.83 9.9 4.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 GAX12816.1 - 0.73 9.7 9.4 2.6 7.9 9.4 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 GAX12816.1 - 0.96 9.6 11.3 0.18 12.0 7.2 1.9 2 0 0 2 2 1 0 RING-variant domain zf-RING-like PF08746.11 GAX12816.1 - 1.4 9.3 6.9 2.6 8.4 6.9 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 GAX12816.1 - 2.5 8.0 7.8 4.6 7.2 7.8 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Pkinase PF00069.25 GAX12817.1 - 4.4e-07 29.5 0.0 6.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 GAX12817.1 - 1.8e-06 27.7 0.1 0.45 10.9 0.2 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 GAX12817.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAX12817.1 - 0.09 13.2 0.0 0.71 10.3 0.0 2.4 1 1 1 2 2 2 0 HEAT repeats NOA36 PF06524.12 GAX12818.1 - 1.4 8.2 13.4 0.35 10.1 8.4 2.0 2 0 0 2 2 2 0 NOA36 protein FAM176 PF14851.6 GAX12818.1 - 2.2 7.9 10.5 2.2 8.0 5.3 2.2 2 0 0 2 2 2 0 FAM176 family LAT PF15234.6 GAX12818.1 - 5 6.8 14.8 0.64 9.7 10.2 1.8 2 0 0 2 2 2 0 Linker for activation of T-cells DUF4611 PF15387.6 GAX12818.1 - 8 6.8 15.2 2.9 8.2 8.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.11 GAX12818.1 - 9 4.2 15.9 0.3 9.1 8.6 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CDC45 PF02724.14 GAX12818.1 - 9.5 4.4 9.1 15 3.8 9.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Meth_synt_2 PF01717.18 GAX12819.1 - 7.2e-140 465.8 0.0 5.7e-138 459.6 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAX12819.1 - 5.2e-78 262.7 0.0 8.7e-73 245.6 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain WD40 PF00400.32 GAX12820.1 - 3.3e-10 40.4 1.7 0.0054 17.5 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX12820.1 - 9.1e-06 25.9 0.0 0.013 15.8 0.1 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 GAX12820.1 - 0.00069 19.0 0.0 0.00082 18.8 0.0 1.2 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal MFS_5 PF05631.14 GAX12821.1 - 3.8e-87 292.5 12.2 5.8e-87 291.9 12.2 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAX12821.1 - 9.3e-20 70.8 50.7 2.1e-17 63.1 33.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M41 PF01434.18 GAX12822.1 - 0.082 12.7 0.1 0.21 11.4 0.1 1.7 1 1 0 1 1 1 0 Peptidase family M41 SIMPL PF04402.14 GAX12822.1 - 0.12 12.9 0.3 0.12 12.9 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF541) ANAPC4_WD40 PF12894.7 GAX12823.1 - 4.1e-14 52.6 2.9 0.0032 17.7 0.1 5.4 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX12823.1 - 5.7e-12 46.0 11.8 0.0013 19.5 0.3 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Nbas_N PF15492.6 GAX12823.1 - 0.012 15.0 0.3 1.8 7.8 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 GAX12823.1 - 0.013 14.5 0.1 8.3 5.3 0.0 3.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 GAX12823.1 - 0.021 14.7 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term DUF2028 PF09667.10 GAX12823.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) MAP65_ASE1 PF03999.12 GAX12823.1 - 0.59 8.8 2.7 0.78 8.4 2.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Acyltransferase PF01553.21 GAX12825.1 - 2.8e-11 43.2 0.0 4.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NAD_binding_1 PF00175.21 GAX12826.1 - 1.5e-29 102.8 0.0 2.2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX12826.1 - 1.3e-28 99.3 0.0 1.9e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAX12826.1 - 6.8e-05 23.0 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain YscW PF09619.10 GAX12826.1 - 0.15 12.4 0.2 6.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Type III secretion system lipoprotein chaperone (YscW) UPF0564 PF10595.9 GAX12827.1 - 0.041 12.9 11.5 0.059 12.4 11.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Vfa1 PF08432.10 GAX12827.1 - 0.47 10.8 9.6 0.83 10.0 9.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3827 PF12877.7 GAX12827.1 - 1.5 7.1 17.0 2.2 6.5 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Macoilin PF09726.9 GAX12827.1 - 1.7 7.1 11.4 2.4 6.6 11.4 1.1 1 0 0 1 1 1 0 Macoilin family Nucleo_P87 PF07267.11 GAX12827.1 - 5.5 5.7 12.7 9.6 4.9 12.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Zn_clus PF00172.18 GAX12828.1 - 1.4e-06 28.3 11.0 1.4e-06 28.3 11.0 2.4 3 1 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 GAX12829.1 - 2.6e-10 40.7 0.8 0.0046 17.8 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX12829.1 - 2.1e-05 24.7 0.0 0.026 14.8 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 GAX12829.1 - 0.00091 18.6 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Mito_carr PF00153.27 GAX12832.1 - 1.1e-63 211.2 4.9 4.5e-22 77.8 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2205 PF10224.9 GAX12832.1 - 0.11 12.5 0.3 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 Short coiled-coil protein DUF3591 PF12157.8 GAX12833.1 - 1.7e-57 195.1 0.0 1.2e-42 146.2 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 GAX12833.1 - 1.8e-20 72.8 0.0 4.5e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain BLOC1_2 PF10046.9 GAX12833.1 - 0.67 10.3 4.4 2.7 8.4 0.3 3.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PHM7_cyt PF14703.6 GAX12833.1 - 6.9 6.9 9.1 0.23 11.7 1.1 2.6 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter PAS_9 PF13426.7 GAX12834.1 - 7.9e-08 32.5 0.0 3.1e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 PAS domain bZIP_1 PF00170.21 GAX12834.1 - 8.4e-06 25.8 4.3 3e-05 24.0 4.3 1.9 1 0 0 1 1 1 1 bZIP transcription factor PAS_8 PF13188.7 GAX12834.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 GAX12834.1 - 0.002 18.2 4.4 0.002 18.2 4.4 2.8 2 0 0 2 2 2 1 Basic region leucine zipper PAS PF00989.25 GAX12834.1 - 0.0064 16.5 0.0 0.0064 16.5 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 GAX12834.1 - 0.026 14.8 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 PAS fold tRNA-synt_1b PF00579.25 GAX12835.1 - 2.4e-18 66.5 0.0 5.8e-18 65.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) ERG2_Sigma1R PF04622.12 GAX12835.1 - 0.0065 15.8 0.0 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 ERG2 and Sigma1 receptor like protein BaffR-Tall_bind PF09256.10 GAX12836.1 - 0.93 9.3 3.1 4.1 7.3 1.1 2.2 1 1 1 2 2 2 0 BAFF-R, TALL-1 binding Yip1 PF04893.17 GAX12837.1 - 4.4e-10 39.5 17.8 1.3e-09 38.0 17.8 1.9 1 1 0 1 1 1 1 Yip1 domain Fer4_24 PF18109.1 GAX12837.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain Transketolase_N PF00456.21 GAX12838.1 - 3e-148 493.2 0.0 5.6e-148 492.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAX12838.1 - 1.9e-44 151.5 0.0 1.3e-43 148.7 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX12838.1 - 1.6e-06 28.0 0.0 8e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAX12838.1 - 7e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Terpene_synth PF01397.21 GAX12838.1 - 0.0051 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain TPP_enzyme_C PF02775.21 GAX12838.1 - 0.057 13.2 0.0 0.45 10.3 0.0 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Sigma70_r2 PF04542.14 GAX12839.1 - 1.6e-19 69.5 0.0 3e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GAX12839.1 - 4.4e-17 61.3 3.8 7.6e-17 60.6 0.6 2.9 4 0 0 4 4 4 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 GAX12839.1 - 2.7e-10 40.2 5.9 1.6e-09 37.7 1.1 2.7 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 GAX12839.1 - 0.033 14.2 0.2 0.099 12.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 zf-TAZ PF02135.16 GAX12840.1 - 5.6e-10 39.5 9.9 5.6e-10 39.5 9.9 2.1 2 0 0 2 2 2 1 TAZ zinc finger VP_N-CPKC PF11475.8 GAX12840.1 - 0.034 14.0 0.2 0.12 12.3 0.2 1.9 1 0 0 1 1 1 0 Virion protein N terminal domain Sld5 PF05916.11 GAX12844.1 - 1.9e-16 60.5 0.2 3.6e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein RusA PF05866.11 GAX12845.1 - 3e-16 60.1 0.0 4.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA cPLA2_C2 PF18695.1 GAX12845.1 - 0.067 13.2 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Cytosolic phospholipases A2 C2-domain Ribosomal_S28e PF01200.18 GAX12846.1 - 3.8e-32 110.1 1.3 4.5e-32 109.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Sulfotransfer_3 PF13469.6 GAX12847.1 - 3.4e-05 24.4 4.6 0.045 14.1 0.0 3.4 2 1 1 3 3 3 2 Sulfotransferase family RNase_H2_suC PF08615.11 GAX12847.1 - 3.9 7.6 6.5 51 4.0 0.0 2.5 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Connexin PF00029.19 GAX12847.1 - 4.7 6.9 8.2 48 3.6 6.7 2.2 2 0 0 2 2 2 0 Connexin Zip PF02535.22 GAX12849.1 - 6.4e-21 74.9 10.8 2.6e-20 72.9 10.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Acyltransferase PF01553.21 GAX12851.1 - 1.7e-12 47.1 0.0 7.2e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Orf78 PF06024.12 GAX12851.1 - 0.16 12.3 1.2 8.7 6.7 0.0 3.4 4 0 0 4 4 4 0 Orf78 (ac78) MFS_3 PF05977.13 GAX12851.1 - 0.17 10.2 1.9 0.26 9.6 1.9 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector ABC1 PF03109.16 GAX12852.1 - 1.5e-20 73.5 0.0 1.3e-19 70.6 0.0 2.2 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 GAX12852.1 - 0.00021 20.7 0.0 0.0007 19.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 GAX12852.1 - 0.032 14.1 1.4 0.087 12.7 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAX12852.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_transf_8 PF01501.20 GAX12854.1 - 6.2e-05 22.7 1.6 0.0085 15.7 0.1 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAX12854.1 - 0.032 13.6 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Amino_oxidase PF01593.24 GAX12855.1 - 2.2e-13 50.3 0.0 5.4e-12 45.7 0.0 2.8 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX12855.1 - 8.2e-09 35.6 0.1 2.3e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX12855.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAX12855.1 - 0.0063 16.1 0.1 0.35 10.4 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX12855.1 - 0.016 14.4 0.5 0.076 12.1 0.4 2.0 2 0 0 2 2 2 0 FAD binding domain DUF4748 PF15932.5 GAX12855.1 - 0.19 11.5 1.3 0.63 9.8 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Abhydrolase_1 PF00561.20 GAX12858.1 - 1.7e-31 109.8 0.1 5.1e-30 105.0 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAX12858.1 - 0.00065 19.8 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 GAX12858.1 - 0.0009 19.9 0.0 0.0018 18.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L20 PF00453.18 GAX12860.1 - 1.8e-39 134.1 5.5 2.2e-39 133.8 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 ApbE PF02424.15 GAX12860.1 - 0.025 14.1 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 ApbE family AAA_2 PF07724.14 GAX12861.1 - 5e-48 163.5 0.0 5.9e-41 140.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAX12861.1 - 1e-27 97.2 0.0 5.9e-14 52.6 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_9 PF17871.1 GAX12861.1 - 2e-24 85.5 0.0 5e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 GAX12861.1 - 6.7e-17 61.8 0.0 1.9e-10 40.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX12861.1 - 2.3e-12 47.6 7.8 2.5e-07 31.2 0.1 5.5 4 2 1 5 5 4 2 AAA ATPase domain ClpB_D2-small PF10431.9 GAX12861.1 - 2.6e-11 43.4 0.1 8.6e-11 41.8 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 GAX12861.1 - 3.7e-11 43.5 2.1 6.2e-05 23.3 0.4 4.9 4 2 0 4 4 3 2 AAA domain Sigma54_activat PF00158.26 GAX12861.1 - 3.5e-10 39.8 0.0 6.2e-07 29.3 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 GAX12861.1 - 2e-08 33.9 0.2 0.022 14.1 0.2 3.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX12861.1 - 4.9e-07 29.4 0.0 0.026 14.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAX12861.1 - 1e-06 28.6 0.0 0.0088 15.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 GAX12861.1 - 2.1e-06 27.3 0.0 0.011 15.1 0.0 3.7 2 1 0 2 2 2 1 Bacterial TniB protein Torsin PF06309.11 GAX12861.1 - 3.3e-05 24.0 0.0 0.00059 19.9 0.0 2.8 3 0 0 3 3 3 1 Torsin RuvB_N PF05496.12 GAX12861.1 - 6e-05 22.8 0.0 2 8.1 0.0 4.2 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 GAX12861.1 - 0.0001 22.4 0.0 0.14 12.2 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 GAX12861.1 - 0.00012 21.9 0.3 0.15 11.9 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAX12861.1 - 0.00014 22.4 0.1 0.9 10.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 GAX12861.1 - 0.00024 21.5 0.0 0.47 10.9 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_14 PF13173.6 GAX12861.1 - 0.00027 21.0 0.0 0.051 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GAX12861.1 - 0.00029 20.8 0.0 0.5 10.4 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAX12861.1 - 0.00046 20.4 0.0 0.55 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 GAX12861.1 - 0.00048 19.3 0.0 0.56 9.3 0.0 2.7 2 0 0 2 2 2 2 MCM P-loop domain AAA_30 PF13604.6 GAX12861.1 - 0.00059 19.6 0.3 1.9 8.2 0.0 3.7 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.6 GAX12861.1 - 0.0012 19.2 2.8 0.025 14.9 0.0 3.5 5 0 0 5 5 2 1 AAA domain AAA_24 PF13479.6 GAX12861.1 - 0.0013 18.4 0.0 0.69 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GAX12861.1 - 0.0027 17.2 0.0 0.8 9.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 GAX12861.1 - 0.0032 16.6 0.0 0.06 12.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 GAX12861.1 - 0.0039 17.1 0.0 0.27 11.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 GAX12861.1 - 0.0046 16.6 0.0 5.2 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 GAX12861.1 - 0.0077 15.5 0.0 1.4 8.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 GAX12861.1 - 0.0081 16.4 0.0 2.9 8.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 GAX12861.1 - 0.0094 16.2 0.1 1.8 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAX12861.1 - 0.013 16.0 0.0 1.7 9.1 0.0 2.9 2 0 0 2 2 2 0 ABC transporter TIP49 PF06068.13 GAX12861.1 - 0.018 14.3 0.0 0.24 10.6 0.0 2.3 3 0 0 3 3 2 0 TIP49 P-loop domain AAA_29 PF13555.6 GAX12861.1 - 0.026 14.3 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 GAX12861.1 - 0.028 13.5 0.0 7.3 5.6 0.0 2.9 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 GAX12861.1 - 0.044 12.9 0.0 3.8 6.6 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 GAX12861.1 - 0.047 14.2 0.0 16 5.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain DEAD PF00270.29 GAX12861.1 - 0.05 13.4 0.2 8.4 6.1 0.1 3.1 2 2 1 3 3 2 0 DEAD/DEAH box helicase SRP54 PF00448.22 GAX12861.1 - 0.055 13.1 0.5 3 7.4 0.0 3.2 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain Clp_N PF02861.20 GAX12861.1 - 0.13 12.4 0.1 11 6.3 0.2 2.8 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component NTPase_1 PF03266.15 GAX12861.1 - 0.14 12.1 0.2 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 NTPase DNA_pol3_delta2 PF13177.6 GAX12861.1 - 0.16 11.8 0.0 8.7 6.1 0.0 2.9 3 0 0 3 3 2 0 DNA polymerase III, delta subunit MCR PF18509.1 GAX12863.1 - 0.78 9.4 2.5 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Magnetochrome domain ClpB_D2-small PF10431.9 GAX12864.1 - 2.1e-09 37.3 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein HATPase_c PF02518.26 GAX12864.1 - 0.066 13.7 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Molybdopterin_N PF18364.1 GAX12867.1 - 0.054 13.5 0.3 9.2 6.4 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain Corona_NS8 PF12093.8 GAX12868.1 - 0.094 13.3 1.4 12 6.5 0.3 2.6 2 0 0 2 2 2 0 Coronavirus NS8 protein Myotub-related PF06602.14 GAX12869.1 - 1.2e-107 359.9 0.1 1.5e-107 359.6 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 GAX12869.1 - 0.0034 17.4 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF4019 PF13211.6 GAX12869.1 - 0.089 13.2 0.1 0.28 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) MGAT2 PF05060.14 GAX12870.1 - 4.5e-29 101.6 0.4 3.7e-26 92.0 0.1 2.8 1 1 1 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) RVT_2 PF07727.14 GAX12872.1 - 2.3e-15 56.9 0.6 3.9e-14 52.9 0.6 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG6_N PF17675.1 GAX12872.1 - 0.014 15.9 3.9 0.014 15.9 3.9 3.5 3 0 0 3 3 3 0 Apg6 coiled-coil region Phage-tail_2 PF09096.10 GAX12872.1 - 0.11 12.5 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 Sec34 PF04136.15 GAX12872.1 - 0.16 11.9 4.4 0.12 12.3 2.2 1.9 2 0 0 2 2 2 0 Sec34-like family DUF4446 PF14584.6 GAX12872.1 - 0.92 9.5 6.9 6.9 6.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PRIMA1 PF16101.5 GAX12873.1 - 0.06 13.4 7.6 0.15 12.1 7.6 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Apis_Csd PF11671.8 GAX12873.1 - 1.9 8.5 5.7 0.54 10.3 1.9 2.0 2 0 0 2 2 2 0 Complementary sex determiner protein COPIIcoated_ERV PF07970.12 GAX12875.1 - 9.7e-31 107.3 1.2 1.7e-30 106.5 1.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX12875.1 - 1.3e-25 89.5 0.4 2.6e-25 88.6 0.4 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 GAX12875.1 - 1.4e-20 73.2 0.1 4.7e-20 71.5 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin DIOX_N PF14226.6 GAX12876.1 - 5.1e-28 98.2 0.0 6.8e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal His_Phos_2 PF00328.22 GAX12877.1 - 3e-18 66.3 2.4 6.2e-17 62.0 0.1 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cation_ATPase_C PF00689.21 GAX12878.1 - 1.1e-40 139.3 0.1 1.1e-40 139.3 0.1 2.8 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAX12878.1 - 1.5e-39 135.4 2.3 1.5e-39 135.4 2.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAX12878.1 - 1.8e-21 77.4 0.0 4.1e-19 69.7 0.0 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX12878.1 - 1.9e-20 72.7 0.0 3.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAX12878.1 - 2.6e-17 62.3 0.1 7.5e-17 60.8 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX12878.1 - 5.3e-06 26.4 0.7 0.0047 16.7 1.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX12878.1 - 0.021 15.2 0.1 0.26 11.7 0.0 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4577 PF15145.6 GAX12878.1 - 0.52 10.4 2.3 2.8 8.0 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) MFS_MOT1 PF16983.5 GAX12879.1 - 5.5e-56 187.7 33.2 2.9e-30 104.9 4.1 4.1 4 0 0 4 4 4 4 Molybdate transporter of MFS superfamily Mitofilin PF09731.9 GAX12880.1 - 2.9e-38 132.1 20.7 4.5e-38 131.5 20.7 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF1192 PF06698.11 GAX12880.1 - 0.0053 16.8 0.4 0.0053 16.8 0.4 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1192) FAD-SLDH PF12318.8 GAX12880.1 - 1.1 9.3 4.6 4.6 7.3 3.4 2.6 2 1 1 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase SIS PF01380.22 GAX12882.1 - 1e-31 109.5 1.4 6.2e-15 55.2 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAX12882.1 - 1.1e-23 83.9 0.2 2.5e-23 82.8 0.2 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX12882.1 - 4.9e-15 55.5 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAX12882.1 - 6.7e-06 25.2 0.2 1.6e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II bact-PGI_C PF10432.9 GAX12882.1 - 0.014 15.5 0.0 0.22 11.5 0.0 2.9 2 1 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain Toprim_3 PF13362.6 GAX12882.1 - 0.46 10.9 2.8 3.8 8.0 0.6 3.3 4 0 0 4 4 4 0 Toprim domain Oxidored_q3 PF00499.20 GAX12883.1 - 0.0019 17.9 0.1 1.4 8.6 0.0 2.2 2 0 0 2 2 2 2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Abhydrolase_9_N PF15420.6 GAX12883.1 - 0.021 14.8 0.4 0.047 13.7 0.1 1.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus BPD_transp_2 PF02653.16 GAX12883.1 - 2.5 7.2 7.8 6 5.9 7.8 1.6 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF1430 PF07242.11 GAX12883.1 - 6.2 7.1 7.0 0.92 9.8 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) Peptidase_M8 PF01457.16 GAX12885.1 - 1.4e-10 40.5 0.0 3.5e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Leishmanolysin CASP_C PF08172.12 GAX12885.1 - 1.1 8.6 3.2 2.5 7.4 3.2 1.5 1 0 0 1 1 1 0 CASP C terminal Peptidase_M8 PF01457.16 GAX12886.1 - 6.2e-11 41.7 0.0 1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin DUF2889 PF11136.8 GAX12886.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) Peptidase_M8 PF01457.16 GAX12887.1 - 3.7e-07 29.2 0.0 9e-07 27.9 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin DUF3306 PF11748.8 GAX12887.1 - 3.1 8.7 5.4 3.6 8.5 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Peptidase_M8 PF01457.16 GAX12889.1 - 4.3e-08 32.3 0.0 8.5e-08 31.3 0.0 1.4 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 GAX12890.1 - 2.3e-10 39.8 0.0 4.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin Mitofilin PF09731.9 GAX12890.1 - 5.7 5.7 12.0 8.3 5.1 12.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RecA PF00154.21 GAX12891.1 - 4.4e-123 409.9 0.1 6.5e-123 409.3 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 GAX12891.1 - 5.3e-10 39.0 0.1 3.2e-09 36.4 0.1 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 GAX12891.1 - 5.9e-08 32.3 1.2 9e-07 28.5 0.3 2.6 2 1 0 2 2 2 1 KaiC AAA_24 PF13479.6 GAX12891.1 - 5.2e-06 26.3 0.0 8.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAX12891.1 - 3.7e-05 23.7 0.0 8.3e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAX12891.1 - 0.0011 19.4 0.3 0.0045 17.4 0.1 2.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 GAX12891.1 - 0.0011 18.6 2.9 0.03 13.9 0.7 2.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 GAX12891.1 - 0.0029 18.0 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 GAX12891.1 - 0.055 14.0 0.1 0.39 11.2 0.1 2.3 1 1 0 1 1 1 0 ABC transporter AAA_35 PF14516.6 GAX12891.1 - 0.062 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.14 GAX12891.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_M8 PF01457.16 GAX12892.1 - 9.5e-11 41.1 0.0 1.4e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 GAX12892.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M8 PF01457.16 GAX12893.1 - 1.6e-13 50.2 0.0 2.4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 GAX12893.1 - 0.038 13.9 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Matrixin Gag_spuma PF03276.14 GAX12893.1 - 1.5 7.2 5.3 2.3 6.5 5.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein UPF0016 PF01169.19 GAX12894.1 - 2.7e-35 120.5 27.6 3.1e-20 72.3 6.8 2.7 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 DSPn PF14671.6 GAX12897.1 - 5.6e-35 120.8 0.2 2.8e-27 95.9 0.0 2.8 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 GAX12897.1 - 1.3e-10 41.2 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX12897.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAX12897.1 - 0.0032 17.6 0.1 0.0075 16.4 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAX12897.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Ras PF00071.22 GAX12898.1 - 3.5e-49 166.5 0.0 4.2e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX12898.1 - 2.9e-31 108.2 0.0 4.4e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX12898.1 - 2.2e-11 43.5 0.0 2.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX12898.1 - 6.1e-07 29.5 0.0 8.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX12898.1 - 0.00034 21.0 0.0 0.00071 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 GAX12898.1 - 0.00043 19.9 0.0 0.0074 15.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX12898.1 - 0.00067 19.6 0.1 0.0047 16.9 0.2 2.0 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 GAX12898.1 - 0.0009 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAX12898.1 - 0.011 15.5 0.1 0.035 13.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAX12898.1 - 0.012 15.4 0.1 0.18 11.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 GAX12898.1 - 0.018 15.0 0.1 0.052 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX12898.1 - 0.02 15.2 0.1 0.064 13.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX12898.1 - 0.023 15.2 0.0 0.024 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 GAX12898.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 GAX12898.1 - 0.058 13.9 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 GAX12898.1 - 0.078 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 GAX12898.1 - 0.12 11.5 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Gtr1_RagA PF04670.12 GAX12898.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MCM PF00493.23 GAX12898.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Sigma70_ner PF04546.13 GAX12899.1 - 0.014 15.3 1.7 0.02 14.8 1.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4168 PF13767.6 GAX12899.1 - 0.052 14.7 3.9 0.079 14.2 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) HD_2 PF12917.7 GAX12899.1 - 0.071 12.9 1.5 0.37 10.5 0.1 2.0 1 1 1 2 2 2 0 HD containing hydrolase-like enzyme LRS4 PF10422.9 GAX12899.1 - 0.22 11.1 3.1 0.27 10.8 3.1 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 OmpH PF03938.14 GAX12899.1 - 0.4 11.0 7.9 0.54 10.6 7.9 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2533 PF10752.9 GAX12899.1 - 4.9 7.7 6.3 12 6.5 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2533) Pkinase PF00069.25 GAX12900.1 - 4.6e-11 42.6 0.0 9.1e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12900.1 - 9.7e-09 34.9 0.0 1.9e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 GAX12900.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 UPF0302 PF08864.10 GAX12902.1 - 0.022 14.8 0.3 0.057 13.5 0.3 1.7 1 0 0 1 1 1 0 UPF0302 domain Fzo_mitofusin PF04799.13 GAX12902.1 - 0.21 11.1 5.7 5 6.7 0.4 2.5 2 0 0 2 2 2 0 fzo-like conserved region Baculo_PEP_C PF04513.12 GAX12902.1 - 0.29 11.2 2.5 0.28 11.2 1.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliT PF05400.13 GAX12902.1 - 0.41 11.5 8.5 0.19 12.6 3.0 3.0 3 1 0 3 3 3 0 Flagellar protein FliT OmpH PF03938.14 GAX12902.1 - 4.9 7.5 12.6 1 9.7 4.4 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mrpl_C PF18502.1 GAX12902.1 - 9.6 6.5 11.8 0.2 11.9 1.0 2.7 2 1 1 3 3 3 0 54S ribosomal protein L8 C-terminal domain COX4 PF02936.14 GAX12905.1 - 1.1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Ribosomal_L19e PF01280.20 GAX12906.1 - 5.2e-20 72.0 3.5 5.2e-20 72.0 3.5 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e Chloroa_b-bind PF00504.21 GAX12907.1 - 2.3e-26 93.3 0.0 3.6e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SAG PF04092.13 GAX12908.1 - 0.029 15.1 1.7 0.055 14.2 1.7 1.4 1 0 0 1 1 1 0 SRS domain Ig_2 PF13895.6 GAX12910.1 - 0.023 15.0 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Sec66 PF09802.9 GAX12913.1 - 0.067 12.8 0.2 0.26 10.9 0.2 1.9 1 1 0 1 1 1 0 Preprotein translocase subunit Sec66 G-alpha PF00503.20 GAX12914.1 - 1.1e-13 51.1 0.0 2.3e-13 50.1 0.0 1.5 2 0 0 2 2 2 1 G-protein alpha subunit GFO_IDH_MocA PF01408.22 GAX12915.1 - 2e-27 96.4 0.4 3.2e-27 95.7 0.4 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAX12915.1 - 2.5e-06 27.5 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 GAX12915.1 - 1.4e-05 25.3 0.1 3.5e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 GAX12915.1 - 0.00043 20.8 0.0 0.00083 19.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 GAX12915.1 - 0.007 17.0 0.1 0.012 16.2 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX12915.1 - 0.0092 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAX12915.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX12915.1 - 0.046 13.8 0.1 0.28 11.3 0.1 2.0 1 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NeuB PF03102.14 GAX12915.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 NeuB family Gp_dh_N PF00044.24 GAX12915.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain T6SS_VasJ PF16989.5 GAX12916.1 - 0.045 13.2 1.7 1 8.8 0.8 2.2 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Ank_2 PF12796.7 GAX12917.1 - 7.5e-11 42.5 0.0 8.9e-06 26.2 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX12917.1 - 2.3e-09 37.3 0.5 0.021 15.1 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX12917.1 - 1.4e-06 28.1 0.6 0.85 10.4 0.0 6.1 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 GAX12917.1 - 7.5e-06 26.4 0.8 0.55 10.9 0.0 5.1 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX12917.1 - 0.0008 19.8 4.8 10 6.7 0.2 5.4 6 1 0 6 6 6 2 Ankyrin repeat UCH PF00443.29 GAX12918.1 - 9.1e-31 107.3 0.4 2.4e-30 105.9 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX12918.1 - 0.014 15.0 11.3 0.005 16.5 7.1 2.4 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase PolyA_pol_arg_C PF12626.7 GAX12918.1 - 0.081 13.0 0.1 0.3 11.1 0.1 2.0 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus LRV_FeS PF05484.11 GAX12918.1 - 0.73 9.9 4.8 0.94 9.5 0.9 2.3 2 0 0 2 2 2 0 LRV protein FeS4 cluster RNA_POL_M_15KD PF02150.16 GAX12918.1 - 2.1 8.3 4.7 22 5.1 0.2 3.0 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Chalcone_3 PF16036.5 GAX12919.1 - 3.2e-06 27.4 0.0 5.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 GAX12919.1 - 0.015 14.7 0.1 2.1 7.7 0.0 2.9 2 1 0 2 2 2 0 Chalcone-flavanone isomerase Chalcone_2 PF16035.5 GAX12919.1 - 0.015 15.0 0.2 3.5 7.4 0.3 2.7 1 1 1 2 2 2 0 Chalcone isomerase like PPR_2 PF13041.6 GAX12920.1 - 1e-09 38.4 0.0 0.082 13.1 0.0 4.0 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 GAX12920.1 - 7e-05 22.8 0.4 1.6 9.1 0.0 4.3 3 0 0 3 3 3 2 PPR repeat FAT PF02259.23 GAX12920.1 - 0.012 14.9 0.1 0.031 13.5 0.1 1.6 1 0 0 1 1 1 0 FAT domain PPR_3 PF13812.6 GAX12920.1 - 0.027 14.5 0.0 21 5.3 0.0 3.5 2 1 0 3 3 3 0 Pentatricopeptide repeat domain FUN14 PF04930.15 GAX12921.1 - 2e-23 82.6 2.5 2.5e-23 82.3 2.5 1.1 1 0 0 1 1 1 1 FUN14 family EF-hand_1 PF00036.32 GAX12921.1 - 0.00049 19.4 0.0 0.00091 18.6 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 GAX12921.1 - 0.0024 17.3 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX12921.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF5320 PF17253.2 GAX12921.1 - 0.046 14.8 0.0 0.075 14.1 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5320) TFIID-31kDa PF02291.15 GAX12922.1 - 4.2e-16 59.1 0.0 9.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 GAX12922.1 - 0.032 14.6 0.1 0.032 14.6 0.1 3.3 3 1 0 3 3 3 0 Core histone H2A/H2B/H3/H4 DnaJ PF00226.31 GAX12923.1 - 7.6e-15 54.8 0.2 1.6e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3395 PF11875.8 GAX12923.1 - 0.00012 22.0 0.7 0.0064 16.4 0.7 3.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) Fructosamin_kin PF03881.14 GAX12924.1 - 3.4e-72 243.1 0.0 4.3e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 GAX12924.1 - 1.9e-06 28.0 0.0 2.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HMG_box PF00505.19 GAX12925.1 - 2.2e-12 47.2 10.8 2.2e-12 47.2 10.8 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX12925.1 - 1.1e-10 41.9 6.2 1.1e-10 41.9 6.2 1.9 2 1 0 2 2 2 1 HMG-box domain YABBY PF04690.13 GAX12925.1 - 0.33 11.5 4.5 0.14 12.7 0.6 2.1 2 0 0 2 2 2 0 YABBY protein SR-25 PF10500.9 GAX12925.1 - 2.6 7.6 16.8 0.18 11.4 8.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltransf_25 PF13649.6 GAX12926.1 - 5.7e-10 39.8 0.1 1.9e-08 34.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 GAX12926.1 - 1.1e-09 38.4 0.1 2e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 GAX12926.1 - 6.7e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX12926.1 - 3.1e-07 30.3 0.2 1.6e-05 24.7 0.1 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 GAX12926.1 - 1.2e-05 25.9 0.0 0.00011 22.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX12926.1 - 3.3e-05 23.9 0.1 0.00012 22.1 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX12926.1 - 4.3e-05 23.1 0.1 0.0001 21.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX12926.1 - 0.0001 21.8 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 GAX12926.1 - 0.00057 19.8 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX12926.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX12926.1 - 0.0023 17.3 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX12926.1 - 0.0026 18.5 0.0 0.0085 16.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX12926.1 - 0.003 16.9 0.2 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PRMT5_C PF17286.2 GAX12926.1 - 0.0042 17.0 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_16 PF10294.9 GAX12926.1 - 0.006 16.3 0.3 0.014 15.1 0.3 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Leader_Trp PF08255.11 GAX12927.1 - 0.22 11.6 1.7 0.58 10.2 1.7 1.7 1 0 0 1 1 1 0 Trp-operon Leader Peptide Cpn10 PF00166.21 GAX12928.1 - 7.4e-30 102.9 0.0 8.2e-30 102.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cupin_6 PF12852.7 GAX12928.1 - 0.014 15.2 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Cupin Myb_Cef PF11831.8 GAX12929.1 - 1.1e-25 90.6 16.6 1.1e-25 90.6 16.6 3.8 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 GAX12929.1 - 9.2e-19 67.4 7.5 4.3e-09 36.4 2.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX12929.1 - 1.1e-17 64.0 6.5 3.1e-11 43.3 3.8 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 GAX12929.1 - 0.029 14.5 2.9 1.4 9.0 1.1 4.4 4 2 1 5 5 5 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PARP_reg PF02877.14 GAX12929.1 - 0.2 11.8 4.6 0.26 11.4 1.1 2.8 2 1 1 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain Guanylate_cyc PF00211.20 GAX12930.1 - 6.8e-45 152.9 0.0 1.2e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX12930.1 - 1.4e-28 100.2 1.2 3.5e-28 98.9 1.2 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase IBR PF01485.21 GAX12931.1 - 1.1e-12 48.0 20.7 6.9e-11 42.2 9.8 5.8 3 1 2 5 5 5 2 IBR domain, a half RING-finger domain Ank_2 PF12796.7 GAX12931.1 - 5.9e-12 46.0 0.0 4.1e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX12931.1 - 1.5e-11 44.5 1.3 0.00043 20.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX12931.1 - 7.9e-11 41.9 0.5 1.1e-06 28.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAX12931.1 - 3.3e-09 36.2 0.2 0.00053 20.2 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAX12931.1 - 8.6e-09 35.5 0.2 0.0016 18.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) zf-C3HC4 PF00097.25 GAX12931.1 - 0.0055 16.5 17.1 0.0055 16.5 17.1 5.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.6 GAX12931.1 - 0.025 14.4 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain zf-RING_11 PF17123.5 GAX12931.1 - 1.2 9.0 9.1 0.98 9.2 6.5 2.3 2 0 0 2 2 2 0 RING-like zinc finger Asparaginase PF00710.20 GAX12934.1 - 1e-58 198.0 0.0 1.6e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 GAX12934.1 - 5.6e-28 97.4 0.1 1e-27 96.6 0.1 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ribosomal_L27A PF00828.19 GAX12935.1 - 2.3e-36 125.3 1.2 3.5e-36 124.7 1.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF2312 PF10073.9 GAX12936.1 - 0.065 12.9 0.1 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Nup84_Nup100 PF04121.13 GAX12938.1 - 1.7e-66 224.8 0.6 1.8e-64 218.2 0.6 2.2 1 1 1 2 2 2 2 Nuclear pore protein 84 / 107 Laminin_EGF PF00053.24 GAX12939.1 - 0.037 14.2 1.7 0.037 14.2 1.7 4.5 4 1 1 5 5 5 0 Laminin EGF domain SAP PF02037.27 GAX12940.1 - 1.7e-57 190.3 19.0 8e-14 51.0 0.3 6.2 7 0 0 7 7 7 5 SAP domain HeH PF12949.7 GAX12940.1 - 1.9e-05 24.3 7.0 0.46 10.2 0.1 5.1 4 1 0 4 4 4 3 HeH/LEM domain Telomere_Sde2_2 PF13297.6 GAX12940.1 - 0.0019 17.8 0.7 1.3 8.7 0.1 3.6 4 0 0 4 4 4 2 Telomere stability C-terminal Ish1 PF10281.9 GAX12940.1 - 0.012 15.9 0.1 32 4.9 0.0 4.4 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein Drc1-Sld2 PF11719.8 GAX12941.1 - 0.011 15.4 1.6 0.015 14.8 1.6 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein PPR_2 PF13041.6 GAX12941.1 - 0.053 13.7 0.1 0.49 10.6 0.1 2.5 2 1 0 2 2 2 0 PPR repeat family Bap31_Bap29_C PF18035.1 GAX12942.1 - 0.0013 18.7 7.9 0.0031 17.5 7.6 1.8 1 1 1 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain SPX PF03105.19 GAX12942.1 - 0.011 15.6 6.4 0.014 15.3 6.4 1.1 1 0 0 1 1 1 0 SPX domain V_ATPase_I PF01496.19 GAX12942.1 - 0.017 13.1 5.0 0.017 13.1 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RILP PF11461.8 GAX12942.1 - 0.029 14.6 10.2 0.065 13.5 0.4 2.7 1 1 1 2 2 2 0 Rab interacting lysosomal protein Fib_alpha PF08702.10 GAX12942.1 - 0.097 12.9 4.8 0.073 13.3 3.2 1.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AATF-Che1 PF13339.6 GAX12942.1 - 0.1 13.3 7.3 0.13 13.0 7.3 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor PBP1_TM PF14812.6 GAX12942.1 - 6.3 7.2 13.3 0.13 12.7 1.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SET PF00856.28 GAX12943.1 - 8.2e-10 39.3 0.2 1.4e-07 32.0 0.1 3.2 2 1 0 3 3 3 1 SET domain eIF-5_eIF-2B PF01873.17 GAX12944.1 - 2.9e-35 120.7 0.3 5.9e-35 119.7 0.3 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF4892 PF16234.5 GAX12944.1 - 0.0012 18.3 0.1 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4892) CxC1 PF18802.1 GAX12944.1 - 0.59 10.3 2.9 1.8 8.8 0.1 2.6 3 0 0 3 3 3 0 CxC1 like cysteine cluster associated with KDZ transposases DUF1754 PF08555.10 GAX12944.1 - 0.63 10.9 12.2 1.1 10.1 12.1 1.5 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) NARP1 PF12569.8 GAX12944.1 - 3.4 6.5 10.4 4.3 6.1 10.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SUZ PF12752.7 GAX12945.1 - 1e-11 45.4 3.2 1e-11 45.4 3.2 2.3 2 0 0 2 2 2 1 SUZ domain DEAD PF00270.29 GAX12946.1 - 5.6e-25 88.1 0.0 1.3e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12946.1 - 9.5e-17 61.3 0.0 1.8e-15 57.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX12946.1 - 1.4e-09 38.2 0.0 3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX12946.1 - 0.00089 19.5 0.6 0.01 16.1 0.4 2.7 1 1 1 2 2 2 1 AAA domain T4SS-DNA_transf PF02534.14 GAX12946.1 - 0.073 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SRP54 PF00448.22 GAX12946.1 - 0.11 12.1 0.1 0.35 10.5 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain SLD5_C PF16922.5 GAX12947.1 - 0.00055 20.1 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 GAX12947.1 - 0.001 19.5 0.1 0.002 18.6 0.1 1.6 1 1 0 1 1 1 1 GINS complex protein DEAD PF00270.29 GAX12949.1 - 3.4e-39 134.4 0.0 2.2e-37 128.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX12949.1 - 0.0021 18.4 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAX12949.1 - 0.089 13.1 1.1 0.92 9.8 1.1 2.5 1 1 0 1 1 1 0 AAA domain Dsh_C PF12316.8 GAX12949.1 - 1 9.7 4.1 0.69 10.3 1.6 1.9 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4604 PF15377.6 GAX12949.1 - 9.5 6.6 31.8 9.2 6.7 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) FKBP_C PF00254.28 GAX12950.1 - 4.5e-12 46.1 0.0 5.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Chitin_synth_2 PF03142.15 GAX12951.1 - 9.1e-161 536.0 1.2 1.3e-160 535.5 1.2 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 GAX12951.1 - 1e-11 44.8 0.1 5.3e-10 39.3 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAX12951.1 - 7.2e-11 42.4 6.2 1.9e-10 41.0 6.2 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX12951.1 - 1.2e-06 28.5 0.1 0.00028 20.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX12951.1 - 2.1e-06 27.6 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX12951.1 - 0.079 12.4 0.1 2 7.9 0.0 2.8 3 0 0 3 3 3 0 Glycosyl transferase family 21 DUF4148 PF13663.6 GAX12952.1 - 0.038 14.2 3.9 0.46 10.7 5.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4148) TIL PF01826.17 GAX12952.1 - 0.28 11.4 11.1 1.1 9.6 11.1 1.8 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain C_tripleX PF02363.19 GAX12952.1 - 5.7 7.4 7.5 11 6.6 2.6 2.3 2 0 0 2 2 2 0 Cysteine rich repeat NYN_YacP PF05991.11 GAX12953.1 - 3.5e-27 95.4 6.7 4.9e-13 49.4 0.0 2.7 3 0 0 3 3 3 2 YacP-like NYN domain DUF3328 PF11807.8 GAX12953.1 - 0.08 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) SLAC1 PF03595.17 GAX12954.1 - 1.9e-27 96.4 23.3 1.9e-27 96.4 23.3 2.2 2 0 0 2 2 2 1 Voltage-dependent anion channel DUF4395 PF14340.6 GAX12954.1 - 5.6e-21 75.2 12.4 5.6e-21 75.2 12.4 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4395) Glutaredoxin PF00462.24 GAX12954.1 - 4.4e-13 49.2 0.2 1.3e-12 47.7 0.2 1.9 1 0 0 1 1 1 1 Glutaredoxin Hemerythrin PF01814.23 GAX12954.1 - 1.4e-05 25.7 8.2 7.8e-05 23.3 7.8 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Thioredoxin_2 PF13098.6 GAX12954.1 - 0.012 16.0 0.4 0.15 12.6 0.1 2.9 3 1 0 3 3 3 0 Thioredoxin-like domain DUF836 PF05768.14 GAX12954.1 - 0.02 15.3 0.2 0.059 13.8 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) adh_short PF00106.25 GAX12955.1 - 3e-23 82.3 0.0 1e-19 70.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX12955.1 - 7.2e-10 38.8 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX12955.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Fer2 PF00111.27 GAX12956.1 - 9.6e-07 28.7 0.3 1.6e-06 27.9 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 GAX12956.1 - 0.0049 16.9 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GHMP_kinases_N PF00288.26 GAX12957.1 - 9.5e-12 45.0 1.5 9.5e-12 45.0 1.5 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAX12957.1 - 4.6e-06 26.9 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4235 PF14019.6 GAX12957.1 - 0.1 12.7 2.3 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) HSP20 PF00011.21 GAX12959.1 - 2e-18 66.4 0.6 3.2e-18 65.8 0.6 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 GAX12959.1 - 0.0059 17.6 0.2 0.01 16.8 0.1 1.5 1 1 0 1 1 1 1 CS domain ArsA_HSP20 PF17886.1 GAX12959.1 - 0.019 14.5 0.1 0.039 13.5 0.1 1.6 1 1 0 1 1 1 0 HSP20-like domain found in ArsA SPX PF03105.19 GAX12960.1 - 1e-19 71.7 23.2 4e-12 46.8 12.0 2.7 1 1 1 2 2 2 2 SPX domain CTP_transf_like PF01467.26 GAX12960.1 - 9.1e-09 35.7 0.0 3.8e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 GAX12960.1 - 0.0049 16.8 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD synthetase KLRAQ PF10205.9 GAX12960.1 - 0.067 13.4 0.7 0.24 11.7 0.7 1.9 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein AKNA PF12443.8 GAX12960.1 - 0.094 13.4 0.4 1.7 9.3 0.1 2.6 2 0 0 2 2 2 0 AT-hook-containing transcription factor CENP-K PF11802.8 GAX12960.1 - 0.79 9.3 5.1 1.6 8.3 5.1 1.5 1 1 0 1 1 1 0 Centromere-associated protein K Exostosin PF03016.15 GAX12961.1 - 1.5e-27 96.6 0.5 3.2e-27 95.5 0.5 1.5 1 1 0 1 1 1 1 Exostosin family Podoplanin PF05808.11 GAX12963.1 - 5.8 7.0 8.7 9.7 6.3 8.7 1.3 1 0 0 1 1 1 0 Podoplanin HSP9_HSP12 PF04119.12 GAX12964.1 - 4.1e-07 30.3 63.1 0.0002 21.7 7.0 9.1 6 4 3 9 9 9 6 Heat shock protein 9/12 YtxH PF12732.7 GAX12964.1 - 0.00087 19.8 37.9 2.7 8.6 1.3 7.2 3 2 1 4 4 4 3 YtxH-like protein Pre-PUA PF17832.1 GAX12964.1 - 0.066 13.9 1.6 3.1 8.6 0.1 3.0 3 0 0 3 3 3 0 Pre-PUA-like domain Herpes_US9 PF06072.11 GAX12965.1 - 0.031 14.1 2.3 8.5 6.3 0.2 3.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 BRAP2 PF07576.12 GAX12965.1 - 0.43 10.8 2.4 13 6.1 0.1 2.6 2 0 0 2 2 2 0 BRCA1-associated protein 2 EF-hand_11 PF08976.11 GAX12966.1 - 0.059 14.2 0.3 0.16 12.9 0.3 1.7 1 0 0 1 1 1 0 EF-hand domain DUF883 PF05957.13 GAX12967.1 - 5.1e-15 55.8 62.9 0.0057 17.2 9.3 8.0 2 1 7 9 9 9 8 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 GAX12967.1 - 1.5e-13 51.1 53.1 1.3e-07 31.6 22.1 4.2 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GAX12967.1 - 8e-13 48.7 92.8 0.0049 17.4 8.8 9.0 2 1 5 7 7 7 4 YtxH-like protein LEA_4 PF02987.16 GAX12967.1 - 8.6e-10 38.5 123.2 0.00043 20.3 6.8 9.8 3 2 7 11 11 11 7 Late embryogenesis abundant protein DUF842 PF05811.13 GAX12967.1 - 3.4e-05 23.5 27.1 0.12 12.0 4.5 4.9 1 1 4 5 5 5 4 Eukaryotic protein of unknown function (DUF842) ApoLp-III PF07464.11 GAX12967.1 - 0.019 15.1 59.2 0.029 14.4 21.9 5.1 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 GAX12967.1 - 0.09 10.7 18.9 0.16 9.9 18.9 1.4 1 0 0 1 1 1 0 Prominin ApoO PF09769.9 GAX12967.1 - 0.13 12.3 35.4 3.3 7.7 1.3 7.3 1 1 4 5 5 5 0 Apolipoprotein O Mitofilin PF09731.9 GAX12967.1 - 0.21 10.4 85.4 1.9 7.2 27.0 3.1 1 1 2 3 3 3 0 Mitochondrial inner membrane protein HisKA_3 PF07730.13 GAX12967.1 - 0.31 11.6 24.4 32 5.2 1.1 8.2 2 1 6 8 8 8 0 Histidine kinase YbjQ_1 PF01906.17 GAX12967.1 - 2.5 8.8 13.8 2.3 8.9 0.8 4.2 2 1 2 4 4 4 0 Putative heavy-metal-binding DUF1664 PF07889.12 GAX12967.1 - 9.8 6.2 33.6 0.79 9.8 3.3 4.9 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DUF2817 PF10994.8 GAX12968.1 - 1.2e-67 228.8 0.0 1.4e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 GAX12968.1 - 0.0026 16.9 0.0 0.0062 15.7 0.0 1.7 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Lipase_GDSL_2 PF13472.6 GAX12969.1 - 2.1e-17 64.1 0.1 5e-17 62.9 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX12969.1 - 3.8e-07 30.3 0.0 7.7e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TPR_14 PF13428.6 GAX12971.1 - 4.4e-12 45.8 11.9 0.54 11.2 0.0 11.3 6 3 4 11 11 11 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX12971.1 - 6.7e-06 25.7 4.5 0.00034 20.1 3.0 2.8 1 1 1 2 2 2 1 MalT-like TPR region TPR_15 PF13429.6 GAX12971.1 - 0.00012 21.4 19.0 0.00024 20.4 0.0 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX12971.1 - 0.014 15.7 3.6 3.7 7.9 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX12971.1 - 0.024 14.8 0.4 27 5.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX12971.1 - 0.1 13.0 3.1 14 6.3 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAX12971.1 - 0.22 11.5 15.1 1.1 9.2 0.0 5.9 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_4 PF07721.14 GAX12971.1 - 9.6 7.2 6.7 62 4.7 0.5 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4131 PF13567.6 GAX12972.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4282 PF14110.6 GAX12972.1 - 0.14 12.9 1.3 0.17 12.6 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) UCH PF00443.29 GAX12973.1 - 1.2e-48 165.9 0.0 2e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX12973.1 - 1.2e-13 51.3 0.2 2.7e-08 33.8 0.0 2.4 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_2 PF13240.6 GAX12973.1 - 0.019 14.7 1.7 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain PCB_OB PF17092.5 GAX12973.1 - 0.085 13.6 0.9 0.18 12.6 0.2 1.9 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain Dus PF01207.17 GAX12976.1 - 4e-51 174.0 0.1 1.1e-50 172.5 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Hydrolase_6 PF13344.6 GAX12976.1 - 0.002 18.2 0.0 0.0068 16.5 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-CCCH_3 PF15663.5 GAX12976.1 - 0.0079 16.4 1.8 0.02 15.1 1.1 2.0 2 0 0 2 2 2 1 Zinc-finger containing family NUC153 PF08159.12 GAX12976.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 NUC153 domain Ank_2 PF12796.7 GAX12977.1 - 5.2e-29 100.7 0.0 1.1e-07 32.4 0.0 6.8 3 3 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX12977.1 - 5.2e-25 84.8 7.9 0.031 14.8 0.0 11.0 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 GAX12977.1 - 1.5e-18 66.6 4.7 0.39 11.1 0.0 9.1 7 1 3 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 GAX12977.1 - 1.5e-18 66.3 4.1 0.67 10.5 0.0 9.2 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 GAX12977.1 - 5.2e-13 49.2 3.3 0.008 16.7 0.1 8.3 7 2 1 8 8 8 3 Ankyrin repeats (many copies) GATase_7 PF13537.6 GAX12977.1 - 0.0095 15.8 0.1 0.23 11.4 0.0 3.0 4 0 0 4 4 4 1 Glutamine amidotransferase domain Inositol_P PF00459.25 GAX12978.1 - 7.8e-32 110.9 0.0 8.3e-31 107.5 0.0 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Molybdopterin PF00384.22 GAX12978.1 - 0.082 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Nipped-B_C PF12830.7 GAX12979.1 - 7e-39 133.7 0.0 4.9e-36 124.5 0.0 3.4 4 1 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 GAX12979.1 - 6.9e-10 39.0 3.7 1.7e-07 31.4 0.5 3.2 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 GAX12979.1 - 0.00016 22.0 0.4 0.31 11.5 0.1 3.8 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 GAX12979.1 - 0.00018 21.5 0.7 0.47 10.8 0.0 5.3 5 0 0 5 5 4 1 HEAT repeat Adaptin_N PF01602.20 GAX12979.1 - 0.00051 18.7 1.3 0.03 12.9 0.1 3.2 4 0 0 4 4 4 1 Adaptin N terminal region Cnd3 PF12719.7 GAX12979.1 - 0.0028 16.9 0.3 0.0098 15.1 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 GAX12979.1 - 0.0029 18.1 0.2 0.034 14.7 0.0 3.1 2 1 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 GAX12979.1 - 0.0045 17.1 0.3 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 PHD_2 PF13831.6 GAX12979.1 - 0.016 14.8 11.3 0.04 13.5 11.3 1.7 1 0 0 1 1 1 0 PHD-finger API5 PF05918.11 GAX12979.1 - 0.03 13.1 2.3 0.048 12.5 0.0 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) CLASP_N PF12348.8 GAX12979.1 - 0.04 13.5 1.3 0.87 9.1 0.0 3.1 3 1 0 3 3 3 0 CLASP N terminal PHD PF00628.29 GAX12979.1 - 0.64 10.0 17.4 1.3 8.9 17.4 1.6 1 0 0 1 1 1 0 PHD-finger TFIIB PF00382.19 GAX12980.1 - 7.4e-35 118.8 3.2 5.4e-19 68.0 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GAX12980.1 - 2.4e-16 59.9 4.8 6.7e-16 58.5 4.8 1.8 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 GAX12980.1 - 1.2e-09 37.6 0.5 2.4e-09 36.5 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 GAX12980.1 - 1.1e-05 25.1 0.8 0.045 13.5 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Lar_restr_allev PF14354.6 GAX12980.1 - 0.2 12.1 0.4 0.92 9.9 0.4 2.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 GAX12980.1 - 0.58 9.6 1.9 5.4 6.6 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 GAX12980.1 - 2.7 8.0 5.0 21 5.2 4.7 2.3 1 1 1 2 2 2 0 YhfH-like protein ALMT PF11744.8 GAX12980.1 - 5.1 5.8 5.8 8 5.2 5.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Ank_2 PF12796.7 GAX12981.1 - 1.9e-16 60.4 0.0 1.3e-10 41.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX12981.1 - 3.2e-11 42.4 0.1 0.0032 17.8 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAX12981.1 - 3e-10 40.1 0.0 0.00013 22.2 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX12981.1 - 4.4e-10 39.6 0.1 0.064 13.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 GAX12981.1 - 5e-10 39.7 0.0 0.0022 18.5 0.0 5.1 3 2 2 6 6 6 3 Ankyrin repeats (many copies) MIF4G PF02854.19 GAX12982.1 - 5.8e-29 101.3 0.0 2.6e-14 53.4 0.0 4.4 4 0 0 4 4 4 4 MIF4G domain Upf2 PF04050.14 GAX12982.1 - 1.5e-14 54.8 1.2 1.5e-14 54.8 1.2 3.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 DUF677 PF05055.12 GAX12982.1 - 0.38 9.6 12.0 0.97 8.3 12.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF4085 PF13315.6 GAX12982.1 - 1.2 8.7 6.3 4 7.0 6.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) RIO1 PF01163.22 GAX12983.1 - 2.2e-70 236.1 0.1 2.2e-70 236.1 0.1 2.3 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 GAX12983.1 - 5.6e-05 23.2 0.2 0.00058 19.8 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX12983.1 - 0.0014 17.5 0.0 0.0014 17.5 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase HSF_DNA-bind PF00447.17 GAX12984.1 - 2.9e-17 63.0 0.0 7.1e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding NOA36 PF06524.12 GAX12984.1 - 5.4 6.2 6.1 8.6 5.6 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 GAX12984.1 - 6.7 6.9 10.5 0.29 11.4 3.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Sacchrp_dh_C PF16653.5 GAX12986.1 - 8.9e-75 252.2 0.0 1.5e-74 251.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 GAX12986.1 - 2.3e-22 79.8 0.0 5.7e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 GAX12986.1 - 5.2e-16 59.1 0.0 1.4e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Saccharop_dh_N PF04455.12 GAX12986.1 - 1.1e-06 28.9 0.4 3.2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 LOR/SDH bifunctional enzyme conserved region AlaDh_PNT_C PF01262.21 GAX12986.1 - 0.0075 15.6 0.0 0.063 12.6 0.0 2.3 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 GAX12986.1 - 0.022 15.6 0.0 0.047 14.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 GAX12986.1 - 0.029 14.4 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pro_isomerase PF00160.21 GAX12988.1 - 2.9e-51 173.9 0.0 4.6e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GAX12988.1 - 4.6e-10 39.9 5.5 0.0059 17.4 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX12988.1 - 7.5e-06 26.2 0.0 0.37 11.1 0.0 3.9 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 GAX12988.1 - 0.02 14.8 0.0 0.093 12.7 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat Ank_4 PF13637.6 GAX12989.1 - 4.5e-09 36.7 0.0 9.5e-05 22.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX12989.1 - 1.1e-07 32.4 0.0 3e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX12989.1 - 7.2e-07 29.4 0.4 0.0032 17.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX12989.1 - 0.004 17.5 0.0 0.27 11.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAX12989.1 - 0.009 16.4 0.0 3.5 8.2 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeat PHINT_rpt PF14882.6 GAX12989.1 - 0.01 16.1 0.1 0.026 14.8 0.1 1.7 1 0 0 1 1 1 0 Phage-integrase repeat unit DNA_pol_phi PF04931.13 GAX12989.1 - 0.69 7.9 19.9 1.1 7.3 19.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 GAX12989.1 - 0.71 9.4 7.1 1.4 8.5 7.1 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RXT2_N PF08595.11 GAX12989.1 - 5.5 7.0 10.5 1.1 9.3 5.1 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal ECH_1 PF00378.20 GAX12990.1 - 1.1e-52 178.9 0.0 1.3e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX12990.1 - 4.6e-15 56.0 0.0 6.6e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ATP-synt_F PF01990.17 GAX12990.1 - 0.052 13.9 0.1 0.096 13.0 0.1 1.4 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit CAF1A PF12253.8 GAX12991.1 - 1e-24 86.5 10.8 1e-24 86.5 10.8 4.4 4 1 1 5 5 5 1 Chromatin assembly factor 1 subunit A M157 PF11624.8 GAX12991.1 - 0.051 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 MHC class I-like protein M157 DOT1 PF08123.13 GAX12992.1 - 0.00031 20.3 0.0 0.00043 19.9 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Nuc_N PF14448.6 GAX12993.1 - 0.048 13.5 4.0 0.25 11.2 0.1 4.0 3 0 0 3 3 3 0 Nuclease N terminal SseC PF04888.12 GAX12994.1 - 0.00069 19.3 0.4 0.00086 19.0 0.4 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family SBP_bac_10 PF07596.11 GAX12994.1 - 0.059 13.3 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) DUF677 PF05055.12 GAX12994.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) NYD-SP28 PF14772.6 GAX12994.1 - 0.16 12.0 8.8 0.049 13.7 6.0 1.5 2 0 0 2 2 2 0 Sperm tail Redoxin PF08534.10 GAX12995.1 - 1.1e-22 80.3 0.0 1.6e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAX12995.1 - 5.3e-10 39.3 0.0 7.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family AAA_25 PF13481.6 GAX12995.1 - 0.08 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cuticle_3 PF11018.8 GAX12996.1 - 0.07 13.3 10.9 0.099 12.8 10.9 1.2 1 0 0 1 1 1 0 Pupal cuticle protein C1 Ribosomal_L13 PF00572.18 GAX12997.1 - 8.8e-52 174.6 0.1 1.4e-51 174.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 DUF5320 PF17253.2 GAX12998.1 - 0.013 16.6 0.6 0.028 15.5 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Tristanin_u2 PF16638.5 GAX12998.1 - 0.057 14.3 0.6 0.057 14.3 0.6 2.3 2 1 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Pkinase PF00069.25 GAX12999.1 - 3.2e-69 233.3 0.0 4.6e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX12999.1 - 3.5e-28 98.6 0.0 5.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAX12999.1 - 1.3e-10 41.5 0.0 3.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 GAX12999.1 - 0.00015 20.7 0.8 0.00031 19.6 0.0 1.8 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAX12999.1 - 0.00041 19.8 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GAX12999.1 - 0.0042 16.7 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAX12999.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family COBRA PF04833.15 GAX13000.1 - 0.039 13.9 0.5 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 COBRA-like protein DUF1090 PF06476.12 GAX13000.1 - 0.1 12.8 1.3 8.4 6.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) GDI PF00996.18 GAX13002.1 - 4.4e-181 602.2 0.0 7.4e-181 601.4 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor Glutaminase PF04960.15 GAX13002.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Glutaminase Turandot PF07240.11 GAX13003.1 - 0.23 11.5 1.7 0.61 10.1 1.7 1.8 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Lipoprotein_10 PF03202.13 GAX13003.1 - 3.7 8.0 7.1 1.4 9.4 3.9 1.9 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region DUF2894 PF11445.8 GAX13003.1 - 5.2 7.5 9.7 9.1 6.7 8.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Phage_GPO PF05929.11 GAX13003.1 - 5.9 6.4 11.5 14 5.2 8.5 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase VDE PF07137.11 GAX13004.1 - 2.1e-91 305.7 1.0 3.4e-91 305.0 1.0 1.3 1 0 0 1 1 1 1 VDE lipocalin domain HALZ PF02183.18 GAX13005.1 - 0.62 10.3 4.4 0.15 12.3 0.6 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tail_P2_I PF09684.10 GAX13007.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) IGPS PF00218.21 GAX13008.1 - 9e-25 87.3 0.0 3e-24 85.6 0.0 1.8 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase FIST PF08495.10 GAX13008.1 - 2.1e-10 40.9 2.0 9.8e-10 38.7 0.2 2.7 3 1 0 3 3 3 1 FIST N domain FIST_C PF10442.9 GAX13008.1 - 9.8e-05 22.3 0.2 0.0049 16.9 0.0 2.5 2 0 0 2 2 2 1 FIST C domain DUF4611 PF15387.6 GAX13008.1 - 0.12 12.6 9.9 0.041 14.1 3.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 GAX13008.1 - 0.31 11.1 3.9 0.9 9.6 1.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal E7 PF00527.18 GAX13008.1 - 0.85 9.9 8.4 0.042 14.1 2.7 1.8 2 0 0 2 2 2 0 E7 protein, Early protein FAM176 PF14851.6 GAX13008.1 - 1.1 8.9 6.5 0.82 9.3 1.9 2.2 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 GAX13008.1 - 7.9 6.9 11.7 1 9.8 3.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Metallophos PF00149.28 GAX13009.1 - 4.5e-33 115.5 0.2 6.3e-33 115.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ThiF PF00899.21 GAX13009.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 ThiF family EGF_2 PF07974.13 GAX13010.1 - 0.49 10.8 34.5 1.8 9.0 8.0 4.8 3 2 0 3 3 3 0 EGF-like domain MS_channel PF00924.18 GAX13012.1 - 2.4e-14 53.4 0.6 4.6e-14 52.5 0.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Cullin_binding PF03556.15 GAX13013.1 - 1.8e-23 83.2 0.2 3.5e-23 82.3 0.2 1.5 1 0 0 1 1 1 1 Cullin binding FG-GAP_2 PF14312.6 GAX13014.1 - 8.5e-65 214.8 32.6 6.2e-13 48.8 0.3 8.0 7 2 0 7 7 7 7 FG-GAP repeat HisK_sensor PF18698.1 GAX13014.1 - 7.2e-07 29.6 0.1 0.21 12.0 0.0 4.4 4 0 0 4 4 4 2 Histidine kinase sensor domain FG-GAP PF01839.23 GAX13014.1 - 0.0008 19.5 29.7 1 9.5 0.2 7.5 7 0 0 7 7 7 3 FG-GAP repeat Kelch_3 PF13415.6 GAX13014.1 - 0.0085 16.4 2.1 8.3 6.8 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain PQQ_3 PF13570.6 GAX13014.1 - 0.48 11.0 0.1 0.48 11.0 0.1 5.4 7 0 0 7 7 7 0 PQQ-like domain Kelch_4 PF13418.6 GAX13014.1 - 8.9 6.4 8.8 28 4.8 0.1 4.9 6 0 0 6 6 6 0 Galactose oxidase, central domain SET PF00856.28 GAX13016.1 - 1.5e-10 41.7 0.0 2.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 SET domain PRIMA1 PF16101.5 GAX13018.1 - 0.092 12.8 2.6 0.36 10.9 2.6 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Arg_decarbox_C PF17944.1 GAX13018.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension AAA PF00004.29 GAX13019.1 - 3.5e-06 27.5 0.0 1.4e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIG PF01833.24 GAX13019.1 - 3.8e-05 23.7 0.1 8.3e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 IPT/TIG domain AAA_22 PF13401.6 GAX13019.1 - 0.0019 18.5 0.0 0.0054 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAX13019.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX13019.1 - 0.016 15.6 0.5 0.055 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 GAX13019.1 - 0.019 14.9 0.4 0.067 13.1 0.0 2.2 2 1 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 GAX13019.1 - 0.079 12.9 0.1 0.7 9.8 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 GAX13019.1 - 0.094 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein ThylakoidFormat PF11264.8 GAX13019.1 - 0.27 10.9 8.0 0.27 10.9 0.6 2.9 3 0 0 3 3 3 0 Thylakoid formation protein Complex1_51K PF01512.17 GAX13020.1 - 9.4e-50 168.4 0.0 1.3e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GAX13020.1 - 6.5e-30 103.0 0.0 1.1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GAX13020.1 - 2.9e-09 36.7 0.0 5.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 SLBB domain PsbP PF01789.16 GAX13021.1 - 0.072 13.2 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 PsbP Pkinase PF00069.25 GAX13022.1 - 8.4e-65 218.7 0.0 1.4e-64 218.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13022.1 - 1.8e-34 119.2 0.0 3.4e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX13022.1 - 7.9e-11 42.3 2.6 0.00026 21.4 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX13022.1 - 1.2e-09 37.0 1.8 0.0033 16.9 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 GAX13022.1 - 4.3e-09 35.6 3.4 0.0063 16.4 0.0 4.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.6 GAX13022.1 - 7.8e-07 28.3 1.6 0.017 14.6 0.0 3.6 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 GAX13022.1 - 6.7e-06 25.6 0.0 0.00014 21.3 0.0 2.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 GAX13022.1 - 2.2e-05 23.9 0.1 4.5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX13022.1 - 3.7e-05 22.7 0.1 0.0002 20.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAX13022.1 - 0.0017 18.4 0.3 0.0045 16.9 0.0 1.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family EF-hand_8 PF13833.6 GAX13022.1 - 0.0032 17.3 2.7 8.4 6.3 0.1 4.6 2 1 2 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.6 GAX13022.1 - 0.17 12.3 0.1 27 5.2 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain tRNA-synt_2b PF00587.25 GAX13023.1 - 3.5e-36 124.8 0.0 5.1e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAX13023.1 - 2.2e-19 69.4 0.8 3.5e-19 68.7 0.8 1.3 1 0 0 1 1 1 1 Anticodon binding domain YscW PF09619.10 GAX13023.1 - 0.15 12.5 0.3 0.38 11.1 0.0 1.7 2 0 0 2 2 2 0 Type III secretion system lipoprotein chaperone (YscW) tRNA_SAD PF07973.14 GAX13024.1 - 1.4e-11 44.3 0.0 3.5e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 GAX13024.1 - 4.2e-06 26.7 0.0 8.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain Pesticin PF16754.5 GAX13024.1 - 0.039 13.9 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term Trigger_N PF05697.13 GAX13025.1 - 6e-09 36.4 0.1 9.6e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) Ank_2 PF12796.7 GAX13026.1 - 9.3e-06 26.2 0.0 0.002 18.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX13026.1 - 0.038 14.5 0.0 76 4.4 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 GAX13026.1 - 0.059 13.8 0.1 5.3 7.7 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat PRKCSH_1 PF13015.6 GAX13027.1 - 4e-27 94.8 0.1 8.5e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 GAX13027.1 - 3.6e-15 56.2 6.9 1.5e-14 54.2 6.4 2.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like CLZ PF16526.5 GAX13027.1 - 0.0013 19.1 5.3 0.25 11.7 0.4 3.2 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pox_A_type_inc PF04508.12 GAX13027.1 - 0.026 14.4 1.6 0.026 14.4 1.6 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PRKCSH PF07915.13 GAX13027.1 - 0.037 15.0 0.8 0.037 15.0 0.8 2.1 2 0 0 2 2 1 0 Glucosidase II beta subunit-like protein Unstab_antitox PF09720.10 GAX13027.1 - 0.072 13.2 10.3 0.49 10.5 0.0 3.7 4 0 0 4 4 4 0 Putative addiction module component Nucleo_P87 PF07267.11 GAX13027.1 - 0.18 10.7 6.8 0.26 10.1 6.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1664 PF07889.12 GAX13027.1 - 0.43 10.6 3.8 5.5 7.1 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 GAX13027.1 - 0.52 10.8 3.8 13 6.3 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 GAX13027.1 - 1.5 8.6 11.4 0.44 10.3 0.3 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 PBP1_TM PF14812.6 GAX13027.1 - 4.1 7.8 9.1 8.8 6.8 9.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sugarporin_N PF11471.8 GAX13027.1 - 7 6.7 9.2 1.4 8.9 0.5 3.0 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension mTERF PF02536.14 GAX13028.1 - 5e-40 137.4 0.1 6.2e-25 87.8 0.0 4.0 3 1 1 4 4 4 4 mTERF MGDG_synth PF06925.11 GAX13030.1 - 1.5e-20 74.0 0.0 2.2e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 GAX13030.1 - 1e-10 41.9 0.0 2.4e-09 37.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 GAX13030.1 - 0.084 13.3 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferases group 1 Raptor_N PF14538.6 GAX13032.1 - 2.1e-50 170.5 0.0 3.6e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 GAX13032.1 - 2e-08 34.8 3.1 5.5 8.0 0.1 7.5 7 0 0 7 7 7 3 WD domain, G-beta repeat Rab_eff_C PF04698.12 GAX13032.1 - 0.00093 17.6 2.4 0.0021 16.5 2.4 1.5 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus HEAT PF02985.22 GAX13032.1 - 0.0013 18.8 1.0 0.058 13.7 0.1 3.7 4 0 0 4 4 4 1 HEAT repeat ANAPC4_WD40 PF12894.7 GAX13032.1 - 0.0014 18.9 0.1 22 5.4 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF446 PF04287.12 GAX13032.1 - 0.024 14.7 0.2 0.058 13.5 0.2 1.6 1 0 0 1 1 1 0 tRNA pseudouridine synthase C Glycos_transf_1 PF00534.20 GAX13033.1 - 2.3e-36 124.9 0.0 3.4e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX13033.1 - 2.8e-30 105.5 0.0 5.4e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX13033.1 - 1.5e-17 64.2 2.8 3.8e-17 62.8 2.6 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAX13033.1 - 6.1e-13 49.5 0.7 6.1e-13 49.5 0.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX13033.1 - 2.6e-11 43.7 0.0 6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 APG12 PF04110.13 GAX13034.1 - 0.027 14.9 0.0 9 6.8 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF5056 PF16479.5 GAX13034.1 - 0.037 14.3 0.2 11 6.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) SLT_beta PF02258.16 GAX13034.1 - 0.052 13.6 1.3 9.7 6.3 0.1 2.9 2 2 0 2 2 2 0 Shiga-like toxin beta subunit ThiG PF05690.14 GAX13034.1 - 0.072 12.4 0.0 0.34 10.2 0.0 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Mit_proteolip PF08039.11 GAX13034.1 - 0.27 11.7 8.5 4.7 7.7 0.5 3.3 4 0 0 4 4 4 0 Mitochondrial proteolipid PI3K_P85_iSH2 PF16454.5 GAX13035.1 - 0.061 12.9 1.9 0.089 12.4 1.9 1.3 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Nbl1_Borealin_N PF10444.9 GAX13035.1 - 0.74 9.5 4.0 0.91 9.2 0.4 2.6 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal SNARE_assoc PF09335.11 GAX13037.1 - 4e-22 79.0 8.6 1.3e-19 70.9 8.2 2.3 1 1 1 2 2 2 2 SNARE associated Golgi protein DUF1151 PF06625.11 GAX13037.1 - 0.0021 18.0 1.0 0.0035 17.3 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) KRTAP7 PF15034.6 GAX13037.1 - 0.074 14.0 0.4 0.51 11.3 0.1 2.1 2 0 0 2 2 2 0 KRTAP type 7 family DUF2368 PF10166.9 GAX13037.1 - 1.2 8.8 3.1 0.87 9.2 0.1 2.2 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2368) Herpes_US9 PF06072.11 GAX13038.1 - 0.1 12.5 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ion_trans PF00520.31 GAX13039.1 - 1.7e-37 129.0 30.1 2.1e-37 128.7 30.1 1.1 1 0 0 1 1 1 1 Ion transport protein DUF4834 PF16118.5 GAX13039.1 - 0.26 12.3 0.0 0.26 12.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF5313 PF17240.2 GAX13039.1 - 0.51 10.8 3.6 0.84 10.1 1.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5313) LRR_8 PF13855.6 GAX13040.1 - 1.3e-25 89.0 21.5 4.7e-12 45.5 0.9 5.1 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 GAX13040.1 - 1.3e-17 63.5 26.2 7.6e-06 26.2 1.7 6.0 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX13040.1 - 5.1e-11 41.5 17.8 0.28 11.9 0.0 8.4 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_9 PF14580.6 GAX13040.1 - 8.6e-10 38.4 6.8 5.6e-05 22.7 1.1 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 GAX13040.1 - 1.1e-05 25.1 24.5 1.5 9.0 0.1 8.0 9 0 0 9 9 9 3 Leucine Rich repeat LRR_5 PF13306.6 GAX13040.1 - 0.066 13.2 0.0 9.6 6.2 0.0 2.3 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 GAX13040.1 - 0.12 12.5 0.0 2.6 8.2 0.0 2.6 2 1 1 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain SLC3A2_N PF16028.5 GAX13041.1 - 0.045 13.3 0.7 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus UPF0093 PF03653.13 GAX13041.1 - 0.12 12.6 0.3 0.33 11.2 0.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0093) ETRAMP PF09716.10 GAX13041.1 - 0.18 11.9 0.7 0.45 10.6 0.7 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4731 PF15875.5 GAX13041.1 - 0.29 11.4 1.2 6.8 7.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) Diphthamide_syn PF01866.17 GAX13042.1 - 3.1e-69 233.7 0.1 4.4e-69 233.2 0.1 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pkinase PF00069.25 GAX13043.1 - 2.5e-29 102.4 0.0 1.2e-28 100.3 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13043.1 - 7.4e-27 94.3 0.0 3.2e-26 92.2 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Pro_isomerase PF00160.21 GAX13044.1 - 9.7e-45 152.7 0.2 1.2e-44 152.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GYF PF02213.16 GAX13045.1 - 2.6e-16 59.0 0.5 5.2e-16 58.0 0.5 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 GAX13045.1 - 0.0023 17.7 0.2 0.0075 16.1 0.2 1.9 1 0 0 1 1 1 1 GYF domain 2 DUF1415 PF07209.12 GAX13046.1 - 2.3e-40 138.1 0.0 6.2e-40 136.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1415) IPP-2 PF04979.14 GAX13046.1 - 0.031 15.0 0.3 0.062 14.0 0.3 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Ribosomal_L7Ae PF01248.26 GAX13048.1 - 1.2e-23 82.6 0.1 1.3e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 GAX13048.1 - 0.0065 16.6 0.0 0.0076 16.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF521 PF04412.13 GAX13048.1 - 0.013 14.3 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) PRIMA1 PF16101.5 GAX13050.1 - 1.8 8.7 4.2 3.5 7.7 2.8 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF3379 PF11859.8 GAX13051.1 - 0.037 13.4 0.3 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3379) DUF4141 PF13605.6 GAX13051.1 - 0.066 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) RVT_2 PF07727.14 GAX13053.1 - 1.1e-44 152.9 0.0 4.2e-44 151.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX13053.1 - 2.4e-09 37.4 0.1 7.5e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 GAX13053.1 - 9.2e-08 31.8 2.4 2.8e-07 30.3 2.4 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 GAX13053.1 - 1.8e-06 27.8 1.1 1.8e-06 27.8 1.1 2.0 2 0 0 2 2 2 1 Zinc knuckle His_Phos_1 PF00300.22 GAX13054.1 - 3.6e-27 95.3 0.3 4.5e-27 95.0 0.3 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SUKH-3 PF14433.6 GAX13054.1 - 0.12 12.9 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 SUKH-3 immunity protein Lipase_3 PF01764.25 GAX13055.1 - 0.001 18.9 0.2 0.0053 16.6 0.2 2.2 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAX13055.1 - 0.0077 15.8 0.8 1.4 8.4 0.2 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2974) HA PF03457.14 GAX13056.1 - 3.2e-27 94.6 11.6 1.3e-10 41.4 3.4 3.4 3 0 0 3 3 3 3 Helicase associated domain ENT PF03735.14 GAX13056.1 - 0.039 14.0 0.0 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 ENT domain HpaB_N PF11794.8 GAX13056.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AcetylCoA_hydro PF02550.15 GAX13056.1 - 0.088 12.8 0.1 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain Peptidase_M3_N PF08439.10 GAX13056.1 - 0.11 12.8 0.0 57 4.1 0.0 3.2 3 0 0 3 3 3 0 Oligopeptidase F HA PF03457.14 GAX13057.1 - 6.2e-12 45.7 0.5 1.4e-11 44.6 0.5 1.6 1 0 0 1 1 1 1 Helicase associated domain Ank_5 PF13857.6 GAX13058.1 - 1.6e-06 28.3 0.3 1.2e-05 25.4 0.2 2.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX13058.1 - 0.00011 22.3 0.1 0.39 11.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX13058.1 - 0.00024 21.4 1.0 0.077 13.5 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAX13058.1 - 0.00056 20.4 0.1 0.024 15.2 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX13058.1 - 0.0025 18.3 0.3 0.079 13.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) THUMP PF02926.17 GAX13059.1 - 1.3e-17 64.3 0.1 2.4e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 THUMP domain FAM104 PF15434.6 GAX13059.1 - 0.0019 18.7 0.6 0.0038 17.8 0.6 1.6 1 0 0 1 1 1 1 Family 104 Plasmodium_Vir PF05795.11 GAX13060.1 - 6.6 6.0 9.8 9 5.6 9.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ribosomal_L3 PF00297.22 GAX13064.1 - 7.1e-17 61.4 0.9 7.7e-15 54.7 0.4 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 NPA PF16469.5 GAX13064.1 - 0.081 13.5 0.4 0.14 12.7 0.4 1.4 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF5333 PF17267.2 GAX13064.1 - 0.11 12.7 0.4 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5333) Sulf_transp PF04143.14 GAX13065.1 - 1e-14 54.9 21.9 1.6e-10 41.0 3.2 3.6 4 0 0 4 4 4 3 Sulphur transport PPR_2 PF13041.6 GAX13066.1 - 1.5e-17 63.5 0.2 0.0054 16.9 0.0 8.6 8 1 1 9 9 9 4 PPR repeat family Smr PF01713.21 GAX13066.1 - 4.1e-08 33.5 0.0 1.1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Smr domain PPR_3 PF13812.6 GAX13066.1 - 1.1e-06 28.6 1.5 8.2 6.6 0.0 7.7 8 2 0 8 8 8 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX13066.1 - 3.9e-05 23.3 8.0 0.068 12.9 0.4 5.7 6 0 0 6 6 6 2 PPR repeat PPR PF01535.20 GAX13066.1 - 6.5e-05 22.9 20.1 0.16 12.3 0.1 8.6 10 0 0 10 10 10 2 PPR repeat COX5A PF02284.16 GAX13066.1 - 0.042 13.8 0.3 21 5.2 0.0 4.2 4 1 0 5 5 5 0 Cytochrome c oxidase subunit Va DAO PF01266.24 GAX13068.1 - 2.6e-47 162.1 0.4 2.9e-47 161.9 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX13068.1 - 4.8e-05 22.7 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX13068.1 - 0.00029 20.2 0.2 0.0006 19.1 0.0 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 GAX13068.1 - 0.0019 18.4 0.2 0.0046 17.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX13068.1 - 0.13 11.3 0.2 10 5.1 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein NFACT-R_1 PF05670.13 GAX13069.1 - 1.7e-08 35.1 0.0 3.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF4041 PF13250.6 GAX13069.1 - 0.19 11.6 0.3 0.6 10.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Laminin_II PF06009.12 GAX13069.1 - 0.24 11.4 2.4 0.35 10.9 1.0 1.9 2 0 0 2 2 2 0 Laminin Domain II DUF5104 PF17117.5 GAX13070.1 - 0.027 14.9 1.0 0.05 14.0 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5104) End3 PF12761.7 GAX13070.1 - 0.027 14.6 2.1 0.033 14.4 2.1 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3810 PF12725.7 GAX13070.1 - 0.11 11.8 0.3 0.13 11.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TLC PF03219.14 GAX13072.1 - 0.002 16.9 17.3 0.2 10.3 9.7 3.7 2 1 0 2 2 2 2 TLC ATP/ADP transporter SKN1 PF03935.15 GAX13073.1 - 4.5e-58 196.9 6.5 1.5e-44 152.3 3.2 4.4 3 1 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAX13073.1 - 0.00016 21.2 0.1 0.62 9.5 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 EGF_2 PF07974.13 GAX13073.1 - 0.00051 20.4 6.4 0.00051 20.4 6.4 2.4 3 1 0 3 3 3 1 EGF-like domain PT PF04886.12 GAX13073.1 - 8.4 6.0 14.0 0.81 9.3 9.0 2.0 2 0 0 2 2 2 0 PT repeat Methyltransf_25 PF13649.6 GAX13074.1 - 6.6e-09 36.4 0.0 1.6e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX13074.1 - 6.4e-05 23.6 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX13074.1 - 0.00016 22.3 0.0 0.00031 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX13074.1 - 0.00019 21.3 0.0 0.00056 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX13074.1 - 0.00033 20.5 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain YesK PF14150.6 GAX13075.1 - 0.15 12.3 16.0 0.26 11.5 2.9 2.7 2 1 1 3 3 3 0 YesK-like protein TauE PF01925.19 GAX13075.1 - 0.52 9.9 13.5 0.96 9.0 13.5 1.5 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE MerC PF03203.14 GAX13075.1 - 0.87 10.1 11.0 18 5.8 11.0 2.0 1 1 0 1 1 1 0 MerC mercury resistance protein DUF454 PF04304.13 GAX13075.1 - 1 9.4 15.2 1.7 8.6 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF454) SLATT_5 PF18160.1 GAX13075.1 - 1.9 7.8 9.1 0.2 10.9 1.2 2.2 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 YfhO PF09586.10 GAX13075.1 - 2.1 6.5 6.1 2.6 6.2 6.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ceramidase PF05875.12 GAX13075.1 - 2.5 7.5 11.9 3.4 7.0 11.9 1.3 1 0 0 1 1 1 0 Ceramidase DUF3754 PF12576.8 GAX13075.1 - 2.9 7.8 15.7 1.2 9.1 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3754) DUF4267 PF14087.6 GAX13075.1 - 4.2 7.5 11.2 14 5.8 11.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) PsiE PF06146.12 GAX13075.1 - 5.8 7.4 17.4 1.8 9.0 0.3 3.2 2 1 1 3 3 3 0 Phosphate-starvation-inducible E Presenilin PF01080.17 GAX13076.1 - 2.8 6.6 4.5 3.9 6.1 4.5 1.1 1 0 0 1 1 1 0 Presenilin NUC194 PF08163.12 GAX13076.1 - 6.6 5.6 7.3 9.8 5.0 7.3 1.1 1 0 0 1 1 1 0 NUC194 domain AAA PF00004.29 GAX13077.1 - 1.7e-68 229.1 0.0 2.6e-41 141.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX13077.1 - 2.8e-13 50.6 0.5 2.5e-05 24.7 0.1 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 GAX13077.1 - 2.7e-12 46.3 0.9 7.7e-09 35.2 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain IstB_IS21 PF01695.17 GAX13077.1 - 1.5e-11 44.3 0.0 8.6e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 GAX13077.1 - 2.2e-10 40.5 0.0 0.00023 20.9 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX13077.1 - 5.5e-10 39.4 0.0 0.0003 20.8 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX13077.1 - 9.3e-08 32.4 1.0 0.00089 19.5 0.1 4.4 2 2 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 GAX13077.1 - 2.4e-07 31.1 0.0 0.0039 17.5 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_14 PF13173.6 GAX13077.1 - 1.6e-06 28.2 0.0 0.00031 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAX13077.1 - 3.1e-06 27.4 0.0 0.0069 16.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 GAX13077.1 - 6.3e-06 26.0 0.0 0.00058 19.6 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 GAX13077.1 - 1.2e-05 25.5 0.0 0.0085 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAX13077.1 - 2.4e-05 23.9 0.0 0.01 15.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 GAX13077.1 - 6.9e-05 23.4 0.0 0.024 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 GAX13077.1 - 0.00015 21.8 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain Mg_chelatase PF01078.21 GAX13077.1 - 0.00018 20.9 0.0 0.25 10.7 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 GAX13077.1 - 0.00019 21.4 0.0 0.0041 17.0 0.0 2.7 3 0 0 3 3 3 1 Bacterial dnaA protein NACHT PF05729.12 GAX13077.1 - 0.0003 20.8 0.5 0.65 9.9 0.1 3.8 2 2 0 3 3 3 1 NACHT domain TIP49 PF06068.13 GAX13077.1 - 0.00076 18.8 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain ABC_tran PF00005.27 GAX13077.1 - 0.0019 18.7 0.0 0.064 13.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Hpr_kinase_C PF07475.12 GAX13077.1 - 0.0021 17.6 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain ATPase_2 PF01637.18 GAX13077.1 - 0.0025 17.8 0.0 0.2 11.6 0.0 3.1 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 GAX13077.1 - 0.0044 16.3 0.1 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Viral_helicase1 PF01443.18 GAX13077.1 - 0.0046 16.7 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 GAX13077.1 - 0.0072 16.3 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 GAX13077.1 - 0.0081 15.4 0.0 0.84 8.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KTI12 PF08433.10 GAX13077.1 - 0.012 15.1 0.1 0.031 13.7 0.0 1.7 2 0 0 2 2 1 0 Chromatin associated protein KTI12 AAA_3 PF07726.11 GAX13077.1 - 0.024 14.5 0.0 3 7.7 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAX13077.1 - 0.028 13.6 0.3 0.2 10.8 0.0 2.4 2 1 1 3 3 3 0 NB-ARC domain AAA_30 PF13604.6 GAX13077.1 - 0.031 14.0 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 GAX13077.1 - 0.033 14.3 0.0 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 GAX13077.1 - 0.035 13.4 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 KaiC Cytidylate_kin PF02224.18 GAX13077.1 - 0.037 13.8 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 GAX13077.1 - 0.039 13.7 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 GAX13077.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 GAX13077.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 GAX13077.1 - 0.055 13.4 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 GAX13077.1 - 0.14 11.8 0.0 12 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain TLC PF03219.14 GAX13078.1 - 1.9e-16 59.9 16.1 3.3e-10 39.3 8.8 3.1 2 1 0 2 2 2 2 TLC ATP/ADP transporter CENP-N PF05238.13 GAX13078.1 - 0.12 11.6 0.2 0.26 10.5 0.2 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like MFS_1 PF07690.16 GAX13078.1 - 0.85 8.5 32.3 0.082 11.8 23.6 2.9 1 1 1 2 2 2 0 Major Facilitator Superfamily Ribosomal_L28e PF01778.17 GAX13079.1 - 5.7e-35 120.5 0.5 5.7e-35 120.5 0.5 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 GAX13079.1 - 1e-29 103.0 21.3 1e-29 103.0 21.3 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 GAX13079.1 - 0.0069 15.8 19.8 0.0086 15.5 19.8 1.2 1 0 0 1 1 1 1 BUD22 Cwf_Cwc_15 PF04889.12 GAX13079.1 - 0.48 10.1 27.5 0.72 9.5 27.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 GAX13083.1 - 0.36 10.8 4.4 0.59 10.1 4.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Spt5_N PF11942.8 GAX13083.1 - 3.4 8.7 18.0 1.6 9.7 15.2 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FAM176 PF14851.6 GAX13083.1 - 9.7 5.8 6.7 0.84 9.3 2.1 1.6 2 0 0 2 2 2 0 FAM176 family GFO_IDH_MocA PF01408.22 GAX13084.1 - 3e-16 60.3 0.0 5.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAX13084.1 - 0.004 17.2 0.0 0.0081 16.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain G6PD_N PF00479.22 GAX13084.1 - 0.085 13.5 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain BTB PF00651.31 GAX13085.1 - 2.2e-12 47.2 0.3 1.8e-09 37.8 0.0 3.2 1 1 1 2 2 2 2 BTB/POZ domain gag-asp_proteas PF13975.6 GAX13086.1 - 0.13 12.9 0.0 26 5.5 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sulfotransfer_1 PF00685.27 GAX13087.1 - 0.0044 16.5 1.6 0.0092 15.5 0.4 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Pkinase PF00069.25 GAX13088.1 - 5.2e-37 127.6 0.0 1.8e-35 122.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13088.1 - 1.7e-20 73.4 0.0 5.2e-20 71.8 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX13088.1 - 1.8e-05 24.2 0.0 4.2e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAX13088.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AvrRpt-cleavage PF05627.11 GAX13088.1 - 0.14 11.6 0.7 0.34 10.3 0.7 1.6 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr HA PF03457.14 GAX13089.1 - 3e-57 190.8 19.0 4.1e-16 59.1 1.5 4.4 4 0 0 4 4 4 4 Helicase associated domain TUDOR_5 PF18359.1 GAX13089.1 - 0.0033 17.1 0.1 0.0063 16.2 0.1 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF3303 PF11746.8 GAX13089.1 - 0.0062 16.8 0.2 18 5.7 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3303) SOBP PF15279.6 GAX13089.1 - 0.014 16.0 1.8 0.028 15.0 1.8 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein RdRP_3 PF00998.23 GAX13089.1 - 0.15 10.7 9.6 0.58 8.8 0.1 2.7 2 1 1 3 3 3 0 Viral RNA dependent RNA polymerase HA PF03457.14 GAX13090.1 - 9e-23 80.4 8.5 1.3e-15 57.4 1.8 2.9 2 0 0 2 2 2 2 Helicase associated domain TPK_catalytic PF04263.16 GAX13090.1 - 9.3e-18 64.4 0.1 3.2e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 GAX13090.1 - 2.6e-06 27.1 0.0 5.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HA PF03457.14 GAX13091.1 - 2.4e-40 136.7 14.3 5.9e-14 52.2 3.5 3.8 3 0 0 3 3 3 3 Helicase associated domain CSN8_PSD8_EIF3K PF10075.9 GAX13092.1 - 1.7e-18 67.0 0.3 1.1e-17 64.3 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 GAX13092.1 - 0.025 13.9 0.2 0.047 13.1 0.0 1.5 2 0 0 2 2 2 0 SAC3/GANP family Tubulin PF00091.25 GAX13093.1 - 2.3e-51 174.8 0.0 3.5e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAX13093.1 - 6.4e-50 168.5 0.0 9.4e-50 168.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAX13093.1 - 0.0053 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain KIND PF16474.5 GAX13095.1 - 0.072 13.0 1.7 0.85 9.5 0.3 2.1 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain PI3K_p85B PF02192.16 GAX13095.1 - 0.12 12.1 0.1 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Ras PF00071.22 GAX13096.1 - 2.6e-67 225.4 0.8 3.3e-67 225.1 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX13096.1 - 1.1e-36 125.6 1.2 1.8e-36 124.9 0.1 1.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX13096.1 - 1.2e-17 63.9 0.6 2.4e-17 63.0 0.2 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAX13096.1 - 5.9e-06 26.3 0.5 0.11 12.4 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAX13096.1 - 9.4e-06 25.2 0.2 1.7e-05 24.3 0.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX13096.1 - 1.1e-05 25.4 0.1 7.4e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX13096.1 - 3.2e-05 23.4 0.1 3.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX13096.1 - 0.00012 21.7 0.3 0.00028 20.5 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 GAX13096.1 - 0.0012 18.3 0.2 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 GAX13096.1 - 0.0065 16.2 0.1 0.1 12.4 0.0 2.2 1 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 GAX13096.1 - 0.0082 15.7 0.0 0.029 13.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAX13096.1 - 0.017 15.5 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAX13096.1 - 0.031 14.5 0.1 0.065 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GAX13096.1 - 0.032 14.6 0.1 0.47 10.9 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GAX13096.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 GAX13096.1 - 0.058 13.4 0.0 0.095 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3873 PF12989.7 GAX13096.1 - 0.062 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) DUF3533 PF12051.8 GAX13096.1 - 0.094 11.6 2.3 0.12 11.3 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) ABC_tran PF00005.27 GAX13096.1 - 0.097 13.2 0.1 0.17 12.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 GAX13096.1 - 0.099 12.0 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein ETC_C1_NDUFA4 PF04800.12 GAX13097.1 - 2.8e-18 65.9 1.1 4.8e-18 65.2 1.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region MRP-S24 PF14955.6 GAX13097.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 ThiF PF00899.21 GAX13098.1 - 3.5e-14 52.8 0.0 9.3e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 ThiF family Ribosomal_L7Ae PF01248.26 GAX13098.1 - 0.00095 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EF-hand_7 PF13499.6 GAX13099.1 - 1.2e-13 51.3 2.4 1.7e-06 28.4 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX13099.1 - 1.2e-12 46.4 4.2 4.6e-05 22.7 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAX13099.1 - 4.2e-12 45.0 2.4 0.00011 21.8 0.0 4.1 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 GAX13099.1 - 2.1e-08 33.3 0.4 0.0081 15.6 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAX13099.1 - 1.4e-07 31.2 2.6 0.011 15.5 0.1 3.5 3 1 0 3 3 3 2 EF-hand domain pair bZIP_2 PF07716.15 GAX13100.1 - 7.7e-08 32.3 6.3 7.7e-08 32.3 6.3 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX13100.1 - 8.8e-08 32.1 6.4 8.8e-08 32.1 6.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAX13100.1 - 0.0022 18.5 2.9 0.0022 18.5 2.9 2.2 3 0 0 3 3 3 1 bZIP Maf transcription factor FHIPEP PF00771.20 GAX13100.1 - 0.12 10.9 0.1 0.17 10.3 0.1 1.2 1 0 0 1 1 1 0 FHIPEP family Nucleo_P87 PF07267.11 GAX13100.1 - 0.14 11.0 2.2 0.18 10.6 2.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAS_9 PF13426.7 GAX13101.1 - 1.7e-15 57.2 0.0 3.6e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 GAX13101.1 - 3.4e-08 33.4 9.6 7.6e-08 32.3 9.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX13101.1 - 6.9e-07 29.3 9.3 1.4e-06 28.3 9.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.25 GAX13101.1 - 0.00039 20.4 0.0 0.00087 19.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 GAX13101.1 - 0.0022 18.2 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GAX13101.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold bZIP_Maf PF03131.17 GAX13101.1 - 0.25 11.9 8.0 0.42 11.2 8.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor CDC45 PF02724.14 GAX13101.1 - 0.93 7.7 7.0 1.2 7.3 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.12 GAX13101.1 - 1.5 7.7 8.1 5.4 5.9 8.5 1.6 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Snf7 PF03357.21 GAX13102.1 - 8.6e-34 116.6 22.4 1.1e-33 116.3 22.4 1.1 1 0 0 1 1 1 1 Snf7 TerB PF05099.13 GAX13102.1 - 0.22 11.5 10.6 1.1 9.2 10.6 2.1 1 1 0 1 1 1 0 Tellurite resistance protein TerB DUF334 PF03904.13 GAX13102.1 - 0.53 9.8 11.1 0.34 10.4 8.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF334) APC_u15 PF16636.5 GAX13102.1 - 6.8 7.2 7.2 4.6 7.7 4.5 2.0 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Glucokinase PF02685.16 GAX13103.1 - 3e-70 236.7 0.0 3.8e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Glucokinase Topo_Zn_Ribbon PF08272.11 GAX13104.1 - 0.69 9.6 2.6 7.8 6.3 0.2 3.0 2 1 0 2 2 2 0 Topoisomerase I zinc-ribbon-like HMG_box PF00505.19 GAX13105.1 - 3e-07 30.7 0.7 0.01 16.2 0.0 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX13105.1 - 0.0001 22.8 0.6 0.49 11.0 0.0 2.5 2 0 0 2 2 2 2 HMG-box domain Esterase_phd PF10503.9 GAX13105.1 - 0.0096 15.4 0.2 0.025 14.1 0.2 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase PHF12_MRG_bd PF16737.5 GAX13105.1 - 0.023 14.4 0.7 0.099 12.4 0.3 2.4 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain Peptidase_M50 PF02163.22 GAX13106.1 - 4e-07 29.6 11.8 0.00025 20.4 2.0 3.1 2 1 1 3 3 3 2 Peptidase family M50 PI3_PI4_kinase PF00454.27 GAX13107.1 - 1.1e-42 146.6 0.0 2.9e-42 145.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAX13107.1 - 4.7e-28 98.4 0.0 1.2e-27 97.1 0.0 1.8 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 GAX13107.1 - 5.4e-15 54.9 0.2 1.5e-14 53.5 0.2 1.8 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 GAX13107.1 - 0.0085 16.1 0.2 0.27 11.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4135 PF13575.6 GAX13107.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TPR_1 PF00515.28 GAX13107.1 - 0.014 15.2 0.2 0.13 12.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX13107.1 - 0.039 13.6 0.4 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 TPR repeat F1F0-ATPsyn_F PF10791.9 GAX13107.1 - 0.13 12.8 0.0 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Ribosomal_S20p PF01649.18 GAX13107.1 - 0.18 12.4 0.3 1 10.1 0.3 2.3 1 0 0 1 1 1 0 Ribosomal protein S20 SPX PF03105.19 GAX13108.1 - 2.4e-09 37.6 13.7 8.8e-08 32.5 13.7 3.3 1 1 0 1 1 1 1 SPX domain N_Asn_amidohyd PF14736.6 GAX13109.1 - 4.5e-58 196.5 0.0 6.1e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Pkinase PF00069.25 GAX13111.1 - 2e-20 73.3 0.0 5.8e-20 71.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13111.1 - 1.2e-09 37.8 0.0 5.9e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAX13111.1 - 0.00052 20.0 0.0 0.11 12.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAX13111.1 - 0.055 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KTI12 PF08433.10 GAX13112.1 - 1.1e-61 208.7 0.3 2.1e-59 201.2 0.3 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAX13112.1 - 1.1e-05 25.6 0.1 4.3e-05 23.7 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAX13112.1 - 0.00034 21.0 0.9 0.002 18.6 0.0 2.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAX13112.1 - 0.0042 17.4 0.1 0.018 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX13112.1 - 0.012 16.1 0.0 0.032 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PLU-1 PF08429.11 GAX13112.1 - 0.015 14.5 0.4 0.027 13.6 0.4 1.4 1 0 0 1 1 1 0 PLU-1-like protein AAA_14 PF13173.6 GAX13112.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 GAX13112.1 - 0.027 14.9 0.1 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Zeta_toxin PF06414.12 GAX13112.1 - 0.027 13.7 0.0 0.058 12.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 GAX13112.1 - 0.053 13.9 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAX13112.1 - 0.06 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_30 PF13604.6 GAX13112.1 - 0.097 12.4 0.0 3.9 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 GAX13112.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain CLP_protease PF00574.23 GAX13113.1 - 2.9e-80 268.5 0.6 3.8e-80 268.1 0.6 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 GAX13113.1 - 0.0047 16.0 0.0 0.0081 15.2 0.0 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Peptidase_M16_M PF16187.5 GAX13114.1 - 2.1e-80 270.0 0.1 3.8e-80 269.2 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX13114.1 - 3.3e-29 101.8 0.1 1.3e-28 99.9 0.1 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX13114.1 - 1.2e-22 80.8 0.0 5.6e-16 59.1 0.0 3.6 3 0 0 3 3 3 3 Peptidase M16 inactive domain CtIP_N PF10482.9 GAX13115.1 - 0.026 14.6 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain ZapB PF06005.12 GAX13115.1 - 0.05 14.0 0.1 0.081 13.4 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DNA_photolyase PF00875.18 GAX13115.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 DNA photolyase DUF3658 PF12395.8 GAX13115.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function PAP_central PF04928.17 GAX13116.1 - 2.5e-60 203.6 0.0 3.4e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAX13116.1 - 2e-18 66.6 0.1 7.2e-16 58.3 0.1 2.5 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAX13116.1 - 0.00074 19.8 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain ICL PF00463.21 GAX13117.1 - 3.1e-216 718.9 0.1 3.6e-216 718.7 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAX13117.1 - 5.4e-11 42.4 0.1 1.1e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase ubiquitin PF00240.23 GAX13118.1 - 9.6e-24 82.9 0.5 2.3e-23 81.7 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin family HNH_3 PF13392.6 GAX13118.1 - 2.2e-12 46.5 0.1 1.2e-06 28.2 0.0 2.6 2 0 0 2 2 2 2 HNH endonuclease Rad60-SLD PF11976.8 GAX13118.1 - 1.8e-09 37.3 0.3 4.5e-09 36.0 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF1336 PF07059.12 GAX13119.1 - 3.5e-49 167.9 0.0 4.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) LSM PF01423.22 GAX13120.1 - 8.1e-14 51.1 0.0 1.1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX13120.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain WD40_alt PF14077.6 GAX13121.1 - 0.0065 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Alternative WD40 repeat motif Ctr PF04145.15 GAX13121.1 - 0.18 12.4 1.8 0.29 11.8 0.9 1.8 2 0 0 2 2 2 0 Ctr copper transporter family Acetyltransf_1 PF00583.25 GAX13122.1 - 1.6e-07 31.6 0.0 6e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX13122.1 - 1.6e-07 31.6 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX13122.1 - 3.5e-06 27.0 0.0 1.3e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX13122.1 - 0.00015 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAX13122.1 - 0.0094 15.9 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 GAX13122.1 - 0.026 14.0 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 GAX13122.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PP2C PF00481.21 GAX13123.1 - 6.9e-25 88.1 0.0 9.2e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX13123.1 - 0.00029 20.5 0.0 0.0011 18.6 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX13123.1 - 0.0012 18.8 0.0 0.0083 16.1 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Snf7 PF03357.21 GAX13124.1 - 1.8e-36 125.3 20.1 2.4e-36 124.9 20.1 1.1 1 0 0 1 1 1 1 Snf7 Ring_hydroxyl_A PF00848.19 GAX13124.1 - 0.14 12.1 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Radical_SAM PF04055.21 GAX13124.1 - 0.33 11.3 1.1 1.1 9.7 0.1 2.0 1 1 0 2 2 2 0 Radical SAM superfamily RNA_pol_Rpb1_5 PF04998.17 GAX13124.1 - 1.3 8.4 7.1 1.6 8.1 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 ATP_sub_h PF10775.9 GAX13124.1 - 1.6 8.8 6.4 0.14 12.1 0.5 2.3 3 0 0 3 3 3 0 ATP synthase complex subunit h DUF948 PF06103.11 GAX13124.1 - 2.4 8.5 9.3 11 6.3 1.7 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Pup PF05639.11 GAX13124.1 - 2.5 9.1 11.7 3.9 8.5 0.8 3.3 2 1 1 3 3 3 0 Pup-like protein SlyX PF04102.12 GAX13124.1 - 9.8 6.9 8.8 0.9 10.2 0.3 3.2 3 1 1 4 4 4 0 SlyX Chloroa_b-bind PF00504.21 GAX13127.1 - 1.6e-40 139.2 0.3 2.6e-40 138.6 0.2 1.4 1 1 1 2 2 2 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX13128.1 - 6.1e-27 95.1 0.1 2.4e-26 93.2 0.1 1.7 1 1 1 2 2 2 1 Chlorophyll A-B binding protein Glutaredoxin2_C PF04399.13 GAX13129.1 - 3e-29 101.5 0.0 1.2e-27 96.3 0.0 2.1 1 1 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 GAX13129.1 - 1.7e-05 25.1 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX13129.1 - 0.0032 17.7 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAX13129.1 - 0.053 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin 2OG-FeII_Oxy_3 PF13640.6 GAX13131.1 - 4.2e-09 37.2 0.0 8.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_2 PF13532.6 GAX13131.1 - 0.12 12.6 1.0 0.85 9.8 1.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ring_hydroxyl_B PF00866.18 GAX13131.1 - 0.3 11.1 2.0 0.43 10.7 2.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Sen15 PF09631.10 GAX13132.1 - 0.031 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Sen15 protein Rpr2 PF04032.16 GAX13132.1 - 0.094 13.0 0.6 0.35 11.2 0.6 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Sigma70_r3 PF04539.16 GAX13133.1 - 2.8e-18 65.8 2.5 2e-12 47.0 0.3 3.5 3 0 0 3 3 3 3 Sigma-70 region 3 Sigma70_r2 PF04542.14 GAX13133.1 - 2.2e-15 56.2 0.0 5.4e-15 54.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GAX13133.1 - 3e-11 42.6 0.0 1.8e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_15 PF12324.8 GAX13133.1 - 0.035 14.0 0.1 0.83 9.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Coatomer_WDAD PF04053.14 GAX13135.1 - 1.6e-104 350.5 0.0 2.2e-104 350.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 GAX13135.1 - 7.5e-93 311.5 0.0 1.1e-92 310.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 GAX13135.1 - 4.3e-41 138.1 16.6 1.6e-07 31.8 0.4 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX13135.1 - 1.3e-10 41.5 0.2 0.00034 20.9 0.1 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX13135.1 - 0.012 14.3 2.7 0.34 9.5 0.0 3.1 1 1 1 3 3 3 0 Nucleoporin Nup120/160 CDP-OH_P_transf PF01066.21 GAX13136.1 - 7.4e-15 55.5 0.3 7.4e-15 55.5 0.3 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribosomal_L37ae PF01780.19 GAX13137.1 - 1.1e-40 137.6 8.2 1.3e-40 137.4 8.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 GAX13137.1 - 0.12 12.4 4.2 0.19 11.8 4.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Usp PF00582.26 GAX13139.1 - 4.2 7.9 5.3 17 5.9 5.3 2.0 1 1 0 1 1 1 0 Universal stress protein family KH_2 PF07650.17 GAX13140.1 - 2.1e-17 62.7 0.8 4e-17 61.8 0.8 1.5 1 0 0 1 1 1 1 KH domain MMR_HSR1 PF01926.23 GAX13140.1 - 2.6e-17 62.9 0.0 5e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAX13140.1 - 1.3e-08 35.1 0.0 0.0051 16.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 GAX13140.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAX13140.1 - 2.3e-05 24.0 0.0 0.00025 20.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX13140.1 - 0.00029 20.8 0.2 0.083 12.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 GAX13140.1 - 0.021 14.6 0.1 0.045 13.5 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 GAX13140.1 - 0.038 13.3 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Arabinose_trans PF04602.12 GAX13140.1 - 0.064 12.1 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein MMR_HSR1_Xtn PF16897.5 GAX13140.1 - 0.13 12.3 0.1 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Clathrin PF00637.20 GAX13141.1 - 6e-156 512.5 20.1 3.8e-25 88.4 2.8 8.2 8 1 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 GAX13141.1 - 2.5e-26 91.4 0.5 1.4e-25 89.0 0.1 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 GAX13141.1 - 6.3e-08 32.5 0.9 0.0065 16.7 0.0 4.7 5 0 0 5 5 5 2 Clathrin propeller repeat Clathrin-link PF09268.10 GAX13141.1 - 2.9e-06 26.5 1.4 2.4e-05 23.6 0.7 2.6 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 GAX13141.1 - 0.00026 20.8 0.5 2.5 8.4 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX13141.1 - 0.0016 18.4 8.0 2.6 8.4 0.3 6.8 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF1512 PF07431.12 GAX13141.1 - 0.066 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF3440 PF11922.8 GAX13141.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) TPR_12 PF13424.6 GAX13141.1 - 0.16 12.3 1.2 53 4.2 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX13141.1 - 0.26 11.6 5.7 22 5.6 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX13141.1 - 0.28 11.1 9.6 2.3 8.2 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX13141.1 - 2.9 8.2 14.8 1.8 8.8 0.6 5.4 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAX13141.1 - 9.5 7.1 6.6 1.1e+02 3.8 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat CTP_transf_like PF01467.26 GAX13142.1 - 2.7e-08 34.1 0.0 3.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Rieske PF00355.26 GAX13143.1 - 7.6e-09 35.4 0.0 2.5e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 GAX13143.1 - 2.8e-07 30.4 0.0 0.00038 20.3 0.0 2.4 1 1 1 2 2 2 2 Rieske-like [2Fe-2S] domain EGF PF00008.27 GAX13144.1 - 6.3e-06 26.4 33.9 0.0032 17.7 4.0 4.0 3 1 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 GAX13144.1 - 0.00055 20.2 45.1 0.00058 20.2 4.8 4.1 3 1 0 3 3 3 3 EGF-like domain hEGF PF12661.7 GAX13144.1 - 9.6 7.0 30.2 0.91 10.3 4.1 4.7 3 1 0 3 3 3 0 Human growth factor-like EGF WD40 PF00400.32 GAX13146.1 - 3.5e-19 68.8 15.9 0.0002 22.1 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-CCCH PF00642.24 GAX13146.1 - 1.7e-06 27.8 1.6 6.5e-06 25.9 0.6 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAX13146.1 - 2.1e-05 24.4 2.8 2.1e-05 24.4 2.8 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 GAX13146.1 - 3e-05 23.7 1.6 8.9e-05 22.2 1.6 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger ANAPC4_WD40 PF12894.7 GAX13146.1 - 4.5e-05 23.7 0.7 3.7 7.9 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAX13146.1 - 0.0034 16.2 0.1 0.026 13.3 0.0 2.6 2 1 0 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 GAX13146.1 - 0.0038 15.9 0.5 0.22 10.1 0.0 3.0 2 1 1 4 4 4 1 Nucleoporin Nup120/160 Torus PF16131.5 GAX13146.1 - 0.1 13.3 0.1 0.23 12.2 0.1 1.5 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 GAX13146.1 - 0.29 11.7 3.2 0.9 10.1 3.2 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF4392 PF14336.6 GAX13147.1 - 2.9e-81 273.1 0.0 3.6e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1652 PF07865.11 GAX13147.1 - 0.069 13.0 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) ThiS-like PF14453.6 GAX13147.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 ThiS-like ubiquitin NYAP_C PF15452.6 GAX13147.1 - 0.2 11.5 0.3 0.81 9.5 0.1 1.8 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter ATP-synt_ab PF00006.25 GAX13148.1 - 1e-73 247.5 0.0 1.7e-73 246.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 GAX13148.1 - 5.9e-42 143.0 0.1 9e-42 142.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 GAX13148.1 - 5.4e-18 65.3 2.4 1e-17 64.4 2.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 GAX13148.1 - 0.00078 19.5 1.5 0.0049 17.0 1.3 2.2 2 0 0 2 2 2 1 HAS barrel domain Radical_SAM_C PF16199.5 GAX13148.1 - 0.036 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Radical_SAM C-terminal domain BT1 PF03092.16 GAX13149.1 - 1.1e-86 291.2 10.8 1.2e-46 159.1 1.7 3.0 1 1 1 2 2 2 2 BT1 family MFS_1_like PF12832.7 GAX13149.1 - 3.8e-05 22.7 0.0 5.8e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 MFS_1 like family Pkinase PF00069.25 GAX13150.1 - 7.6e-56 189.4 0.0 1.9e-55 188.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13150.1 - 2.7e-52 177.6 0.0 4.4e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NIT PF08376.10 GAX13150.1 - 5.8e-12 46.6 1.1 0.00014 22.5 0.0 2.3 2 0 0 2 2 2 2 Nitrate and nitrite sensing Pkinase_fungal PF17667.1 GAX13150.1 - 1.6e-07 30.5 0.0 6.1e-07 28.5 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 GAX13150.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAX13150.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PK PF00224.21 GAX13151.1 - 4.3e-115 384.3 0.3 5.4e-115 384.0 0.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAX13151.1 - 2.7e-10 40.5 0.2 1.1e-09 38.6 0.2 2.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAX13151.1 - 0.00033 19.9 0.6 0.00063 19.0 0.6 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Glyco_hydro_3_C PF01915.22 GAX13151.1 - 0.019 14.9 0.0 0.084 12.8 0.0 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain PixA PF12306.8 GAX13151.1 - 0.025 14.8 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Inclusion body protein DUF4838 PF16126.5 GAX13151.1 - 0.1 12.0 0.3 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Cuticle_3 PF11018.8 GAX13151.1 - 4.6 7.4 10.7 6.3 7.0 5.1 2.3 1 1 1 2 2 2 0 Pupal cuticle protein C1 Alg14 PF08660.11 GAX13152.1 - 9.3e-56 188.5 0.0 1.7e-55 187.7 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF1995 PF09353.10 GAX13153.1 - 3.9e-27 95.6 0.0 5.3e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) VasL PF12486.8 GAX13153.1 - 0.05 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL Pyrophosphatase PF00719.19 GAX13154.1 - 1.4e-52 177.7 0.2 1.7e-52 177.5 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Rad60-SLD PF11976.8 GAX13156.1 - 9.9e-08 31.7 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like GRDP-like PF07173.12 GAX13156.1 - 0.04 14.6 0.0 0.067 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like ubiquitin PF00240.23 GAX13156.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family zf-Tim10_DDP PF02953.15 GAX13158.1 - 1.3e-18 66.4 4.8 1.9e-18 65.9 4.8 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mito_carr PF00153.27 GAX13159.1 - 6e-23 80.6 4.0 3.4e-11 42.9 0.0 4.6 3 2 1 4 4 4 4 Mitochondrial carrier protein Arrestin_N PF00339.29 GAX13160.1 - 3.5e-11 43.4 0.0 1.3e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAX13160.1 - 4e-09 37.0 0.2 3.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Ribosomal_S7 PF00177.21 GAX13161.1 - 8.3e-35 119.6 0.6 1e-34 119.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AAA PF00004.29 GAX13162.1 - 5.4e-33 114.2 0.0 1.2e-32 113.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX13162.1 - 1.1e-06 28.4 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAX13162.1 - 0.00011 22.4 0.2 0.0023 18.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAX13162.1 - 0.00014 21.1 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAX13162.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX13162.1 - 0.00085 19.3 0.1 0.0036 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAX13162.1 - 0.0011 19.5 0.0 0.0023 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 GAX13162.1 - 0.0012 18.3 0.0 1.3 8.4 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein IstB_IS21 PF01695.17 GAX13162.1 - 0.0017 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 GAX13162.1 - 0.0021 17.4 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 GAX13162.1 - 0.0026 18.1 6.3 0.036 14.4 0.0 3.6 3 2 1 4 4 4 1 AAA ATPase domain Mg_chelatase PF01078.21 GAX13162.1 - 0.0069 15.8 0.3 0.027 13.9 0.2 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX13162.1 - 0.011 15.3 0.1 0.068 12.7 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 GAX13162.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 GAX13162.1 - 0.024 14.8 0.9 0.07 13.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAX13162.1 - 0.03 14.2 0.2 0.15 11.9 0.1 2.1 1 1 1 2 2 2 0 NACHT domain AAA_2 PF07724.14 GAX13162.1 - 0.043 13.9 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 GAX13162.1 - 0.048 14.0 0.0 0.24 11.8 0.0 2.3 2 1 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 GAX13162.1 - 0.093 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAX13162.1 - 0.095 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAX13162.1 - 0.18 11.0 0.0 0.44 9.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain NmrA PF05368.13 GAX13163.1 - 1.1e-39 136.4 0.2 6.8e-23 81.4 0.2 3.1 3 0 0 3 3 3 3 NmrA-like family NAD_binding_10 PF13460.6 GAX13163.1 - 5.6e-12 45.9 0.1 3.5e-07 30.3 0.1 2.3 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 GAX13163.1 - 2.5e-07 30.4 0.2 1.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX13163.1 - 9.4e-05 21.5 0.1 0.025 13.6 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 GAX13163.1 - 0.013 14.9 0.2 0.42 10.1 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase PALP PF00291.25 GAX13163.1 - 0.084 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GDP_Man_Dehyd PF16363.5 GAX13163.1 - 0.12 11.7 0.1 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase SRP40_C PF05022.12 GAX13164.1 - 3.6e-21 75.8 1.6 1.6e-20 73.7 1.6 2.3 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.11 GAX13164.1 - 0.13 12.3 0.4 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 LisH Ribosomal_S10 PF00338.22 GAX13165.1 - 1.6e-27 95.6 0.1 1.9e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NnrU PF07298.11 GAX13166.1 - 3.3e-41 141.1 9.8 7.2e-41 140.0 9.8 1.5 1 0 0 1 1 1 1 NnrU protein PEMT PF04191.13 GAX13166.1 - 0.002 18.5 0.1 0.002 18.5 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF2105 PF09878.9 GAX13166.1 - 0.0089 15.8 0.3 0.022 14.5 0.3 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2105) Peptidase_S9_N PF02897.15 GAX13167.1 - 3.4e-76 256.7 0.3 5e-76 256.2 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 GAX13167.1 - 2.5e-11 43.5 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family HAP1_N PF04849.13 GAX13167.1 - 0.32 10.2 2.4 0.49 9.5 2.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ATP12 PF07542.11 GAX13169.1 - 7e-28 97.3 0.4 7e-28 97.3 0.4 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein DUF1769 PF08588.10 GAX13170.1 - 0.026 14.7 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) DUF3527 PF12043.8 GAX13170.1 - 0.1 12.1 2.6 0.15 11.6 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) SWIRM-assoc_2 PF16496.5 GAX13170.1 - 0.14 11.0 11.2 0.25 10.2 11.2 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Glyco_tran_WbsX PF14307.6 GAX13170.1 - 0.22 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX CLP_protease PF00574.23 GAX13171.1 - 1e-79 266.6 0.0 1.3e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease PurA PF04845.13 GAX13171.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein NAD_binding_1 PF00175.21 GAX13172.1 - 1.3e-28 99.8 0.1 3.4e-28 98.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX13172.1 - 0.005 17.2 0.0 0.0095 16.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAX13172.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.5 1 1 0 1 1 1 0 Ferric reductase NAD binding domain tRNA-synt_1c PF00749.21 GAX13173.1 - 6.8e-97 324.1 0.0 2.1e-96 322.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_bind PF01588.20 GAX13173.1 - 5.3e-28 97.0 0.0 1e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain DUF4537 PF15057.6 GAX13173.1 - 0.1 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Cyto_heme_lyase PF01265.17 GAX13175.1 - 2.2e-44 152.2 17.5 3.7e-24 85.8 5.8 2.3 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase Ldh_1_C PF02866.18 GAX13176.1 - 1.7e-44 151.7 0.0 5.3e-44 150.1 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAX13176.1 - 1.5e-41 141.8 0.1 2.1e-41 141.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAX13176.1 - 4.9e-05 22.5 0.0 8.6e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CPSase_L_D2 PF02786.17 GAX13177.1 - 2.7e-110 366.9 0.3 2e-80 269.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAX13177.1 - 1.1e-51 174.0 0.0 3.7e-51 172.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAX13177.1 - 6.9e-42 143.4 0.0 7.4e-41 140.0 0.0 2.7 3 0 0 3 3 3 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 GAX13177.1 - 3.8e-38 130.6 0.6 1.2e-37 128.9 0.6 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 GAX13177.1 - 2.3e-17 63.1 0.2 5.7e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAX13177.1 - 6.5e-17 61.7 0.2 1.3e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 GAX13177.1 - 6.5e-16 58.3 0.0 6.6e-15 55.1 0.0 2.9 3 0 0 3 3 2 1 MGS-like domain ATPgrasp_Ter PF15632.6 GAX13177.1 - 6.7e-12 45.3 0.0 2.2e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 GAX13177.1 - 3.1e-07 30.6 0.1 0.00062 19.9 0.0 3.2 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 GAX13177.1 - 0.0013 18.6 0.5 0.066 13.0 0.5 2.5 1 1 0 1 1 1 1 Peptidase C26 DUF5371 PF17341.2 GAX13177.1 - 0.048 13.9 0.5 1.3 9.3 0.0 3.1 2 1 1 3 3 2 0 Family of unknown function (DUF5371) GARS_A PF01071.19 GAX13177.1 - 0.051 13.3 0.1 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 GAX13177.1 - 0.088 12.2 0.0 12 5.2 0.0 2.8 3 0 0 3 3 3 0 ATP-grasp domain Peptidase_M17_N PF02789.17 GAX13177.1 - 0.13 12.2 0.2 0.42 10.5 0.0 1.9 2 0 0 2 2 1 0 Cytosol aminopeptidase family, N-terminal domain UBA_6 PF18039.1 GAX13177.1 - 0.13 12.2 0.0 7.3 6.6 0.0 3.5 3 0 0 3 3 3 0 UBA-like domain DUF5333 PF17267.2 GAX13177.1 - 0.16 12.2 0.1 0.63 10.2 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5333) CoA_binding_2 PF13380.6 GAX13177.1 - 0.16 12.5 0.1 0.93 10.0 0.0 2.4 3 0 0 3 3 1 0 CoA binding domain EF-hand_7 PF13499.6 GAX13178.1 - 3.8e-10 40.1 4.6 6.6e-10 39.3 4.6 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX13178.1 - 1.1e-08 34.0 3.3 4.6e-06 25.8 0.5 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX13178.1 - 1.7e-08 33.7 3.0 3.3e-05 23.5 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain Na_Ca_ex PF01699.24 GAX13178.1 - 6.5e-08 32.7 23.8 1.5e-06 28.2 9.8 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_8 PF13833.6 GAX13178.1 - 5.9e-07 29.2 2.8 6.4e-07 29.1 1.2 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GAX13178.1 - 1.8e-05 24.0 1.8 7.7e-05 22.0 0.5 2.3 2 0 0 2 2 2 1 EF hand Cyclin_N PF00134.23 GAX13179.1 - 1.4e-14 53.9 0.2 2.6e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX13179.1 - 0.001 19.1 0.2 0.0032 17.5 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain SF-assemblin PF06705.11 GAX13180.1 - 9.9e-24 84.0 28.9 1.1e-23 83.9 28.9 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 GAX13180.1 - 0.00049 20.2 9.8 0.035 14.2 0.6 2.9 1 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 GAX13180.1 - 0.007 16.5 23.5 0.1 12.7 8.0 2.3 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) YlqD PF11068.8 GAX13180.1 - 0.014 15.8 8.5 0.014 15.8 8.5 3.2 1 1 2 3 3 3 0 YlqD protein MbeD_MobD PF04899.12 GAX13180.1 - 0.03 14.4 4.0 0.03 14.4 4.0 4.3 1 1 4 5 5 5 0 MbeD/MobD like SCP2 PF02036.17 GAX13180.1 - 0.083 13.4 1.8 1.1 9.8 0.1 2.5 2 0 0 2 2 2 0 SCP-2 sterol transfer family FliD_C PF07195.12 GAX13180.1 - 0.4 10.1 9.6 1.4 8.3 0.5 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF3584 PF12128.8 GAX13180.1 - 0.58 7.6 33.1 0.96 6.9 33.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Fzo_mitofusin PF04799.13 GAX13180.1 - 0.96 9.0 19.8 0.081 12.5 5.6 3.6 1 1 2 3 3 3 0 fzo-like conserved region IDEAL PF08858.10 GAX13180.1 - 1.7 8.5 6.3 5.3 6.9 0.6 2.7 2 0 0 2 2 2 0 IDEAL domain NuA4 PF09340.10 GAX13180.1 - 2.1 8.3 6.2 0.93 9.4 1.4 2.6 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF885 PF05960.11 GAX13180.1 - 2.9 7.4 16.5 5.8 6.4 16.5 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Exonuc_VII_L PF02601.15 GAX13180.1 - 4.7 6.7 23.2 1e+03 -1.0 23.2 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1993 PF09351.10 GAX13180.1 - 4.8 7.3 11.2 2.8 8.1 0.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) DUF1640 PF07798.11 GAX13180.1 - 6 6.9 27.3 0.24 11.4 6.9 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) BRI3BP PF14965.6 GAX13180.1 - 6.5 6.2 6.4 2.5 7.6 0.2 2.7 3 0 0 3 3 3 0 Negative regulator of p53/TP53 Rho_Binding PF08912.11 GAX13180.1 - 7.4 7.5 28.3 1.8 9.4 6.9 4.4 1 1 3 4 4 4 0 Rho Binding Lectin_N PF03954.14 GAX13180.1 - 7.5 6.3 11.5 0.81 9.4 1.7 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1674 PF07896.12 GAX13181.1 - 2e-10 41.0 7.6 2.8e-10 40.5 5.8 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) Adeno_PV PF03910.13 GAX13181.1 - 0.019 13.7 0.2 0.02 13.6 0.2 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Nop PF01798.18 GAX13182.1 - 8.2e-90 300.3 0.7 1.6e-89 299.3 0.7 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAX13182.1 - 8.5e-18 64.5 0.5 8.5e-18 64.5 0.5 2.9 3 1 0 3 3 3 1 NOP5NT (NUC127) domain DUF3245 PF11595.8 GAX13182.1 - 0.0056 17.2 20.1 0.014 15.9 20.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) Cdh1_DBD_1 PF18196.1 GAX13182.1 - 0.58 10.5 14.3 1.6 9.0 14.3 1.7 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 PBP1_TM PF14812.6 GAX13182.1 - 0.86 10.0 20.6 1.7 9.1 20.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal U79_P34 PF03064.16 GAX13182.1 - 3.6 6.9 20.7 5.3 6.3 20.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4604 PF15377.6 GAX13182.1 - 3.8 7.9 29.2 7.8 6.9 29.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Rhabdo_glycop PF00974.18 GAX13183.1 - 0.011 14.2 0.2 0.013 14.0 0.2 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DnaJ-X PF14308.6 GAX13184.1 - 6.4e-33 114.0 0.3 6.4e-33 114.0 0.3 2.9 2 2 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAX13184.1 - 5e-24 84.2 0.9 1.7e-23 82.5 0.9 2.0 1 0 0 1 1 1 1 DnaJ domain Ribonuc_red_2_N PF08471.10 GAX13184.1 - 8.7 6.6 10.0 1.8 8.8 1.1 3.1 3 1 0 3 3 3 0 Class II vitamin B12-dependent ribonucleotide reductase Ribosomal_L15e PF00827.17 GAX13185.1 - 2e-91 304.9 7.2 2.3e-91 304.7 7.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L28e PF01778.17 GAX13186.1 - 6.7e-23 81.6 1.5 8.2e-23 81.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family 2OG-FeII_Oxy_3 PF13640.6 GAX13187.1 - 2.6e-15 57.1 0.1 6.9e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily LRR_6 PF13516.6 GAX13188.1 - 6.7e-06 25.8 1.4 1.1 9.5 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich repeat AAA_2 PF07724.14 GAX13189.1 - 6.8e-40 137.0 0.1 4.2e-33 114.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAX13189.1 - 1.7e-15 57.6 0.1 2.2e-06 28.1 0.1 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX13189.1 - 7.6e-09 35.7 0.1 2.3e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX13189.1 - 2.2e-06 28.2 0.4 2.6e-05 24.7 0.0 2.5 2 2 0 2 2 2 1 AAA ATPase domain ClpB_D2-small PF10431.9 GAX13189.1 - 8.6e-06 25.7 0.7 8.6e-06 25.7 0.7 1.9 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein G-alpha PF00503.20 GAX13189.1 - 1.9e-05 24.0 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit MCM PF00493.23 GAX13189.1 - 3.2e-05 23.1 0.0 0.0039 16.3 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 GAX13189.1 - 5.5e-05 23.5 0.0 0.00044 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX13189.1 - 0.00019 21.6 0.1 0.0053 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAX13189.1 - 0.00063 19.2 0.3 0.014 14.8 0.0 2.9 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 GAX13189.1 - 0.00066 19.5 1.1 0.29 10.9 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 GAX13189.1 - 0.0019 17.9 0.0 0.042 13.5 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAX13189.1 - 0.0021 17.4 0.1 0.0065 15.8 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin SseC PF04888.12 GAX13189.1 - 0.005 16.5 3.4 0.21 11.1 0.2 2.1 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family TIP49 PF06068.13 GAX13189.1 - 0.0074 15.5 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 GAX13189.1 - 0.01 15.3 0.1 0.059 12.8 0.0 2.2 2 1 0 2 2 2 0 Bacterial TniB protein DUF2120 PF09893.9 GAX13189.1 - 0.022 14.9 1.6 0.94 9.6 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) AAA_28 PF13521.6 GAX13189.1 - 0.022 15.0 0.6 0.16 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAX13189.1 - 0.026 14.5 0.0 0.17 11.8 0.0 2.1 1 1 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 GAX13189.1 - 0.031 13.8 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 GAX13189.1 - 0.036 14.1 0.1 7.5 6.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX13189.1 - 0.038 14.5 0.0 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 GAX13189.1 - 0.039 13.8 0.0 0.26 11.1 0.0 2.4 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein DEAD PF00270.29 GAX13189.1 - 0.043 13.6 0.3 1.1 9.0 0.0 2.7 2 1 1 3 3 3 0 DEAD/DEAH box helicase NACHT PF05729.12 GAX13189.1 - 0.044 13.7 0.1 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 NACHT domain TsaE PF02367.17 GAX13189.1 - 0.064 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAX13189.1 - 0.065 13.8 0.1 0.19 12.3 0.0 2.0 2 1 0 2 2 1 0 ABC transporter AAA_8 PF12780.7 GAX13189.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 RNA_helicase PF00910.22 GAX13189.1 - 0.11 12.9 0.0 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 GAX13189.1 - 0.13 12.0 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 GAX13189.1 - 0.18 12.1 2.7 0.33 11.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain A_deaminase PF00962.22 GAX13190.1 - 8.4e-75 252.1 0.1 1.1e-74 251.7 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1168 PF06658.12 GAX13191.1 - 4.6e-24 84.8 18.4 6.5e-24 84.3 18.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) VAD1-2 PF15310.6 GAX13191.1 - 0.031 14.2 5.8 0.037 13.9 5.8 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Afaf PF15339.6 GAX13191.1 - 0.2 11.4 4.5 0.32 10.7 4.5 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor Pannexin_like PF12534.8 GAX13191.1 - 1.4 7.9 5.7 1.7 7.7 5.7 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF4192 PF13830.6 GAX13191.1 - 6.1 6.8 10.7 7.7 6.5 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Med14 PF08638.11 GAX13193.1 - 0.00086 18.8 0.1 0.0022 17.5 0.1 1.7 1 1 0 1 1 1 1 Mediator complex subunit MED14 3A PF00803.18 GAX13193.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 3A/RNA2 movement protein family Aldo_ket_red PF00248.21 GAX13194.1 - 1.9e-24 86.4 0.0 3.7e-23 82.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Kin17_mid PF10357.9 GAX13195.1 - 6.5e-38 129.5 9.1 6.5e-38 129.5 9.1 2.6 2 1 1 3 3 3 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 GAX13195.1 - 7.7e-10 38.7 0.6 1.4e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 GAX13195.1 - 5.1e-06 26.2 0.5 5.1e-06 26.2 0.5 2.2 2 0 0 2 2 2 1 KOW motif zf-C2H2_jaz PF12171.8 GAX13195.1 - 0.0068 16.7 2.4 0.0068 16.7 2.4 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding CAML PF14963.6 GAX13195.1 - 0.015 15.4 6.7 0.028 14.5 6.7 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand zf-met PF12874.7 GAX13195.1 - 0.025 14.9 4.2 0.056 13.9 4.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF2470 PF10615.9 GAX13195.1 - 0.036 14.7 0.0 0.17 12.6 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2470) PPP4R2 PF09184.11 GAX13195.1 - 0.92 9.0 15.7 1.6 8.3 15.7 1.3 1 0 0 1 1 1 0 PPP4R2 zf-C2H2_2 PF12756.7 GAX13195.1 - 4.8 7.6 9.6 0.17 12.3 0.6 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Pap_E4 PF02711.14 GAX13195.1 - 5.6 8.0 8.0 0.36 11.8 1.0 2.4 2 1 0 2 2 2 0 E4 protein Sacchrp_dh_NADP PF03435.18 GAX13196.1 - 1.8e-11 44.4 0.1 3e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GAX13196.1 - 0.2 11.5 0.4 3.9 7.3 0.4 2.2 1 1 0 1 1 1 0 NAD(P)H-binding MFS_1 PF07690.16 GAX13197.1 - 1.7e-26 93.0 35.3 1.7e-26 93.0 35.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sin_N PF04801.13 GAX13199.1 - 2.4e-36 125.9 2.4 7.8e-36 124.2 2.4 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region CDC73_C PF05179.14 GAX13199.1 - 0.13 12.0 0.2 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 RNA pol II accessory factor, Cdc73 family, C-terminal SMC_N PF02463.19 GAX13200.1 - 5e-08 32.6 3.3 0.0026 17.2 0.0 2.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAX13200.1 - 1.7e-06 28.7 0.5 6.2e-06 26.8 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX13200.1 - 0.00092 19.5 0.8 0.043 14.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAX13200.1 - 0.0036 17.0 0.2 0.0086 15.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 GAX13200.1 - 0.34 11.0 3.6 0.65 10.1 0.2 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_16 PF13191.6 GAX13200.1 - 3.5 8.0 7.0 2.3 8.6 0.7 3.2 3 1 0 3 3 3 0 AAA ATPase domain SPC22 PF04573.12 GAX13201.1 - 6.1e-47 159.3 0.0 6.8e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Pkinase_Tyr PF07714.17 GAX13202.1 - 8.9e-55 185.8 0.1 3.2e-54 183.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GAX13202.1 - 6.3e-44 150.3 0.0 1.3e-43 149.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 GAX13202.1 - 4.7e-14 52.3 4.7 2.7e-05 24.4 0.1 5.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX13202.1 - 1.8e-08 34.0 6.9 7e-06 25.7 1.6 3.6 2 1 3 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 GAX13202.1 - 1.9e-06 27.5 0.2 1.1e-05 25.0 0.1 2.2 2 1 1 3 3 3 1 Leucine-rich repeat Kdo PF06293.14 GAX13202.1 - 0.028 13.8 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX13202.1 - 0.05 13.5 0.9 0.48 10.3 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family LRR_6 PF13516.6 GAX13202.1 - 0.45 10.7 9.6 29 5.1 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich repeat SHOCT PF09851.9 GAX13202.1 - 1.4 8.7 4.2 0.66 9.8 0.1 2.4 2 0 0 2 2 2 0 Short C-terminal domain Ank_2 PF12796.7 GAX13203.1 - 2.8e-22 79.1 0.6 3.4e-11 43.6 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX13203.1 - 3.9e-21 75.1 0.5 9.4e-09 35.6 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX13203.1 - 4.6e-18 63.5 0.1 2.5e-05 24.3 0.1 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 GAX13203.1 - 2.6e-16 59.4 0.7 8.6e-05 22.8 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX13203.1 - 6.1e-15 54.9 0.1 0.00016 22.0 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat DnaJ PF00226.31 GAX13203.1 - 1.1e-06 28.7 0.4 2.1e-06 27.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 GAX13204.1 - 2.6e-95 320.0 28.7 5.9e-74 249.6 13.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAX13204.1 - 1.5e-29 103.0 45.9 2.3e-28 99.1 27.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAX13204.1 - 0.00047 18.7 1.9 0.00047 18.7 1.9 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.6 GAX13205.1 - 1.3e-07 31.7 0.0 0.00029 20.8 0.0 2.9 2 1 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 GAX13205.1 - 0.00055 19.5 0.0 0.0025 17.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAX13205.1 - 0.0016 18.6 0.1 0.0031 17.6 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ac76 PF05814.11 GAX13205.1 - 0.014 15.4 0.2 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 Orf76 (Ac76) NAD_binding_4 PF07993.12 GAX13205.1 - 0.02 14.1 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Wzz PF02706.15 GAX13205.1 - 0.07 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Chain length determinant protein Acyl-CoA_dh_M PF02770.19 GAX13206.1 - 2.3e-25 88.6 0.0 4e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAX13206.1 - 3.4e-24 85.8 0.3 6.1e-24 84.9 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX13206.1 - 3.1e-21 76.1 0.0 7.9e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAX13206.1 - 2.3e-11 44.1 0.3 6.6e-11 42.6 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HSF_DNA-bind PF00447.17 GAX13207.1 - 2.6e-09 37.6 0.0 5.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding EF-hand_7 PF13499.6 GAX13208.1 - 2.6e-06 27.8 9.8 0.0032 17.9 0.6 5.0 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX13208.1 - 5.6e-05 22.4 8.9 0.7 9.6 0.0 5.6 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 GAX13208.1 - 6.2e-05 22.6 7.5 3.2 7.9 0.0 5.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 GAX13208.1 - 0.0015 18.3 0.1 9.3 6.2 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain pair DUF5601 PF18151.1 GAX13208.1 - 0.056 13.8 0.0 0.52 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) EF-hand_5 PF13202.6 GAX13208.1 - 0.075 12.6 1.3 1.6 8.3 0.0 3.5 5 0 0 5 5 5 0 EF hand RTTN_N PF14726.6 GAX13208.1 - 0.079 13.8 0.0 0.28 12.0 0.0 1.9 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning MscS_TM PF12794.7 GAX13208.1 - 0.45 9.3 1.2 0.51 9.1 0.0 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF3695 PF12494.8 GAX13209.1 - 0.096 12.6 0.7 0.34 10.8 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3695) SOG2 PF10428.9 GAX13209.1 - 0.41 9.8 10.4 0.54 9.4 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein IER PF05760.12 GAX13209.1 - 1.1 9.5 6.7 1.6 9.0 6.7 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Hamartin PF04388.12 GAX13209.1 - 9.9 4.7 9.6 12 4.4 9.6 1.1 1 0 0 1 1 1 0 Hamartin protein RRM_1 PF00076.22 GAX13210.1 - 4.4e-16 58.5 0.0 6.5e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ufd2P_core PF10408.9 GAX13212.1 - 2e-117 393.4 0.0 3.1e-117 392.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 GAX13212.1 - 4.2e-23 81.3 0.2 1.1e-22 79.9 0.2 1.8 1 0 0 1 1 1 1 U-box domain PPR_2 PF13041.6 GAX13213.1 - 6e-17 61.6 7.2 4.6e-07 29.9 0.0 8.2 7 1 1 8 8 8 3 PPR repeat family PPR_1 PF12854.7 GAX13213.1 - 2.4e-07 30.3 3.1 0.025 14.3 0.0 5.6 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 GAX13213.1 - 3.2e-07 30.3 4.3 0.01 15.9 0.3 6.3 8 1 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.20 GAX13213.1 - 3.2e-06 27.0 5.8 0.058 13.7 0.0 6.5 5 1 0 5 5 5 2 PPR repeat RPM2 PF08579.11 GAX13213.1 - 0.00039 20.8 1.7 9.4 6.7 0.0 3.7 3 1 1 4 4 4 2 Mitochondrial ribonuclease P subunit (RPM2) PPR_long PF17177.4 GAX13213.1 - 0.00056 19.3 1.3 0.023 14.1 0.2 2.8 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP DUF3384 PF11864.8 GAX13213.1 - 0.0077 15.2 0.8 0.081 11.8 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) MNE1 PF13762.6 GAX13213.1 - 0.017 15.1 2.1 0.14 12.2 0.2 3.2 4 0 0 4 4 4 0 Mitochondrial splicing apparatus component Thioredoxin_8 PF13905.6 GAX13214.1 - 2e-26 92.2 0.0 4e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 GAX13214.1 - 4.8e-10 39.3 0.0 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAX13214.1 - 3.5e-08 33.9 0.0 6.3e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 GAX13214.1 - 1.3e-05 25.1 0.0 5.4e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 GAX13214.1 - 5.9e-05 23.0 0.0 8.9e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX13214.1 - 7.7e-05 22.4 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 GAX13214.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX13214.1 - 0.015 15.0 0.0 0.064 13.0 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin DUF953 PF06110.11 GAX13214.1 - 0.015 14.9 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) DUF929 PF06053.11 GAX13214.1 - 0.14 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Glutaredoxin PF00462.24 GAX13214.1 - 0.16 12.2 0.0 1.4 9.2 0.0 2.5 3 0 0 3 3 3 0 Glutaredoxin Trypsin PF00089.26 GAX13215.1 - 2.1e-33 116.0 0.0 3.3e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin UPF0126 PF03458.13 GAX13216.1 - 0.27 11.1 9.1 2.5 8.0 0.1 3.1 2 1 1 3 3 3 0 UPF0126 domain Adaptin_N PF01602.20 GAX13217.1 - 2.7e-104 349.6 1.9 3.9e-104 349.1 1.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GAX13217.1 - 1.3e-45 155.2 0.1 5.6e-45 153.2 0.1 2.0 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 GAX13217.1 - 1.2e-33 115.7 0.0 3.7e-33 114.1 0.0 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GAX13217.1 - 1.6e-14 54.0 6.4 2.1e-06 28.0 0.4 5.1 3 2 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 GAX13217.1 - 6.7e-11 42.5 2.0 0.012 15.7 0.0 3.7 3 0 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX13217.1 - 9.9e-05 22.3 12.6 1 9.8 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 GAX13217.1 - 0.00013 22.4 10.3 0.03 14.8 2.8 3.9 2 1 1 3 3 3 2 HEAT-like repeat B2-adapt-app_C PF09066.10 GAX13217.1 - 0.046 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain HEAT_PBS PF03130.16 GAX13217.1 - 0.067 13.9 2.9 25 5.9 0.3 4.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Bep_C_terminal PF17841.1 GAX13217.1 - 0.11 12.7 0.4 4 7.7 0.0 3.2 3 0 0 3 3 3 0 BID domain of Bartonella effector protein (Bep) RIX1 PF08167.12 GAX13217.1 - 0.66 9.7 4.2 27 4.4 0.1 4.1 4 2 1 5 5 5 0 rRNA processing/ribosome biogenesis PPR_2 PF13041.6 GAX13218.1 - 5e-11 42.6 2.0 0.21 11.8 0.0 6.2 5 1 0 5 5 5 3 PPR repeat family PPR_1 PF12854.7 GAX13218.1 - 2.7e-06 27.0 0.2 0.29 10.9 0.0 5.6 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 GAX13218.1 - 5.6e-05 23.1 0.7 2.3 8.3 0.0 4.7 3 1 2 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.20 GAX13218.1 - 0.00068 19.7 6.8 0.063 13.6 0.0 5.3 6 0 0 6 6 6 1 PPR repeat SpvB PF03534.13 GAX13218.1 - 0.12 11.5 0.2 0.19 10.9 0.2 1.2 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein UAA PF08449.11 GAX13219.1 - 1.4e-35 123.0 10.5 1.6e-35 122.8 10.5 1.0 1 0 0 1 1 1 1 UAA transporter family Ceramidase PF05875.12 GAX13219.1 - 0.0016 17.9 0.4 0.0025 17.3 0.4 1.4 1 0 0 1 1 1 1 Ceramidase EamA PF00892.20 GAX13219.1 - 0.0063 16.7 7.8 0.0063 16.7 7.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family Campylo_MOMP PF05538.11 GAX13219.1 - 0.073 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Campylobacter major outer membrane protein Utp12 PF04003.12 GAX13220.1 - 6.8e-20 71.4 0.0 8.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Dip2/Utp12 Family RPN1_RPN2_N PF17781.1 GAX13220.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 RPN1/RPN2 N-terminal domain WD40 PF00400.32 GAX13221.1 - 1.1e-38 130.6 19.5 2.2e-09 37.8 0.2 10.3 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX13221.1 - 6e-29 100.2 0.0 0.00031 21.0 0.0 7.6 5 2 2 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX13221.1 - 9.8e-08 31.3 0.0 0.16 10.9 0.0 4.4 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAX13221.1 - 9.2e-05 21.9 0.0 0.1 11.9 0.0 3.4 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 GAX13221.1 - 0.0015 17.9 0.1 14 4.9 0.0 5.0 4 2 2 6 6 6 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 GAX13221.1 - 0.0018 17.1 0.2 4.3 6.0 0.0 4.7 5 2 2 7 7 7 1 Nup133 N terminal like Frtz PF11768.8 GAX13221.1 - 0.0078 14.6 0.0 2.4 6.4 0.0 3.2 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz CNH PF00780.22 GAX13221.1 - 0.01 15.4 0.0 2.3 7.7 0.0 2.9 2 1 0 2 2 2 0 CNH domain ELYS-bb PF16687.5 GAX13221.1 - 0.011 14.4 0.1 0.46 9.0 0.0 2.7 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin DUF1513 PF07433.11 GAX13221.1 - 0.014 14.5 1.0 2.4 7.2 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1513) WDCP PF15390.6 GAX13221.1 - 0.062 11.7 0.1 0.097 11.0 0.1 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PALB2_WD40 PF16756.5 GAX13221.1 - 0.13 11.2 1.5 2.9 6.7 0.0 3.5 4 1 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Kelch_4 PF13418.6 GAX13221.1 - 0.14 12.2 0.7 32 4.7 0.2 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain GlutR_N PF05201.15 GAX13223.1 - 0.00034 20.4 0.1 0.024 14.4 0.1 2.4 2 0 0 2 2 2 2 Glutamyl-tRNAGlu reductase, N-terminal domain Methyltransf_31 PF13847.6 GAX13224.1 - 1.9e-10 40.7 0.1 3e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX13224.1 - 1.2e-07 31.5 0.3 2.6e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAX13224.1 - 3.8e-07 30.8 0.0 6.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX13224.1 - 5.3e-07 30.3 0.0 1.1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX13224.1 - 3.3e-06 27.6 0.0 6.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAX13224.1 - 2.5e-05 23.8 0.1 4.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 GAX13224.1 - 0.00065 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX13224.1 - 0.0046 16.4 0.1 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 GAX13224.1 - 0.0066 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX13224.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 GAX13224.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DREV PF05219.12 GAX13224.1 - 0.028 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase HTH_15 PF12324.8 GAX13224.1 - 0.028 14.4 0.1 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase GidB PF02527.15 GAX13224.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Hemerythrin PF01814.23 GAX13227.1 - 1.3e-11 45.3 4.3 2.2e-11 44.5 4.3 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF3311 PF11755.8 GAX13227.1 - 0.13 12.2 2.9 0.25 11.3 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) PLATZ PF04640.14 GAX13228.1 - 0.011 16.3 0.2 0.029 15.0 0.2 1.6 1 0 0 1 1 1 0 PLATZ transcription factor F-box-like PF12937.7 GAX13229.1 - 0.013 15.4 0.3 0.048 13.6 0.3 2.1 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 GAX13229.1 - 0.056 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 F-box domain DUF3077 PF11275.8 GAX13229.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) Peptidase_M20 PF01546.28 GAX13230.1 - 9.5e-36 123.4 0.0 1.4e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAX13230.1 - 1.2e-14 54.2 0.0 2.1e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Kelch_4 PF13418.6 GAX13230.1 - 0.086 12.9 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain DnaJ PF00226.31 GAX13232.1 - 1.2e-17 63.8 0.0 4e-16 58.9 0.0 3.2 3 0 0 3 3 3 1 DnaJ domain zf-C3HC4_2 PF13923.6 GAX13232.1 - 8.5e-10 38.3 9.5 8.5e-10 38.3 9.5 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX13232.1 - 5.4e-09 36.2 10.3 1.1e-08 35.2 10.3 1.6 1 0 0 1 1 1 1 Ring finger domain TPR_1 PF00515.28 GAX13232.1 - 2.5e-08 33.4 12.0 0.0036 17.0 0.0 6.6 7 1 0 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX13232.1 - 6.1e-08 33.1 16.6 0.0023 18.4 0.4 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX13232.1 - 5.7e-07 29.8 23.0 0.52 11.3 0.1 6.8 5 2 2 7 7 6 3 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 GAX13232.1 - 7.8e-07 28.9 6.9 1.5e-06 28.0 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX13232.1 - 8.8e-07 28.7 9.0 2e-06 27.5 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX13232.1 - 1.6e-06 27.9 8.2 3.3e-06 27.0 8.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAX13232.1 - 6.4e-06 26.4 7.2 2e-05 24.8 7.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain TPR_12 PF13424.6 GAX13232.1 - 1.3e-05 25.3 24.6 0.017 15.4 0.2 6.6 4 2 2 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX13232.1 - 1.8e-05 24.5 20.9 0.0043 17.0 0.1 7.5 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX13232.1 - 1.9e-05 24.5 17.0 0.034 14.3 0.1 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX13232.1 - 2.3e-05 24.5 5.7 0.53 10.8 0.0 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 GAX13232.1 - 3.2e-05 23.8 5.3 3.2e-05 23.8 5.3 1.9 2 0 0 2 2 1 1 RING-type zinc-finger TPR_16 PF13432.6 GAX13232.1 - 5.1e-05 23.8 18.4 0.0021 18.7 0.1 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GAX13232.1 - 0.00029 20.6 8.2 0.00029 20.6 8.2 1.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 Sina PF03145.16 GAX13232.1 - 0.0015 18.5 0.1 0.0032 17.5 0.1 1.5 1 0 0 1 1 1 1 Seven in absentia protein family TPR_11 PF13414.6 GAX13232.1 - 0.004 16.8 3.2 1.9 8.3 0.0 5.0 4 1 1 5 5 5 1 TPR repeat TPR_6 PF13174.6 GAX13232.1 - 0.0096 16.5 11.9 0.019 15.6 0.3 5.6 6 0 0 6 6 4 1 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 GAX13232.1 - 0.01 15.9 5.1 0.022 14.8 5.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 GAX13232.1 - 0.017 15.2 7.7 0.039 14.1 7.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 GAX13232.1 - 0.024 14.4 4.3 0.19 11.5 5.1 2.2 1 1 1 2 2 2 0 RING-like zinc finger DUF3856 PF12968.7 GAX13232.1 - 0.056 13.5 8.1 8 6.5 0.5 4.2 3 2 0 3 3 2 0 Domain of Unknown Function (DUF3856) Zn_ribbon_17 PF17120.5 GAX13232.1 - 0.08 12.6 7.3 0.089 12.4 5.9 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAX13232.1 - 0.23 11.3 6.8 0.47 10.3 6.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ANAPC3 PF12895.7 GAX13232.1 - 0.35 11.1 17.3 0.37 11.0 0.2 4.6 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 GAX13232.1 - 0.54 10.4 3.2 22 5.2 0.4 4.0 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat zinc-ribbons_6 PF07191.12 GAX13232.1 - 1.4 8.9 8.8 3.4 7.7 8.8 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-C3HC4_4 PF15227.6 GAX13232.1 - 2.2 8.5 8.6 5.5 7.2 8.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TMF_TATA_bd PF12325.8 GAX13232.1 - 3.7 7.8 8.2 1 9.6 0.2 3.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding TPR_7 PF13176.6 GAX13232.1 - 6.5 7.0 10.7 1.9 8.7 0.2 4.9 4 1 1 5 5 4 0 Tetratricopeptide repeat HHH_8 PF14716.6 GAX13232.1 - 9.2 6.7 6.6 72 3.9 0.4 4.2 3 1 0 3 3 3 0 Helix-hairpin-helix domain Pkinase PF00069.25 GAX13233.1 - 5.5e-63 212.8 0.0 1.2e-62 211.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13233.1 - 4.4e-34 118.0 0.0 1.1e-33 116.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX13233.1 - 3.3e-08 33.2 0.0 9.3e-06 25.2 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 GAX13233.1 - 6.7e-05 22.9 0.7 0.0004 20.4 0.7 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family PsaN PF05479.11 GAX13233.1 - 0.04 14.1 0.7 0.2 11.9 0.1 2.3 1 1 1 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Seadorna_VP7 PF07387.11 GAX13233.1 - 0.049 12.7 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF87 PF01935.17 GAX13233.1 - 0.11 12.5 2.8 0.3 11.1 2.8 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain DEAD PF00270.29 GAX13234.1 - 4.5e-44 150.3 0.1 1.1e-43 149.1 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX13234.1 - 2e-30 105.4 0.0 8.8e-30 103.3 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX13234.1 - 1.6e-06 28.2 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAX13234.1 - 7.1e-05 22.3 0.0 7.1e-05 22.3 0.0 2.8 4 0 0 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 GAX13234.1 - 0.0058 16.4 0.3 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAX13234.1 - 0.016 15.5 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain UTP25 PF06862.12 GAX13234.1 - 0.043 12.6 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PhoH PF02562.16 GAX13234.1 - 0.051 13.0 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 GAX13234.1 - 0.094 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 GAX13236.1 - 7.8e-08 31.4 19.0 2.7e-06 26.4 19.0 2.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PalH PF08733.10 GAX13236.1 - 0.011 14.7 2.2 0.023 13.7 2.2 1.5 1 0 0 1 1 1 0 PalH/RIM21 MatP PF06303.12 GAX13238.1 - 0.068 13.7 0.8 0.24 12.0 0.4 2.1 1 1 0 2 2 2 0 MatP N-terminal domain PQQ_2 PF13360.6 GAX13239.1 - 3.3e-12 46.5 1.5 6.2e-06 26.0 0.1 2.6 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 GAX13239.1 - 6.4e-07 29.7 8.3 0.016 15.7 0.2 4.9 6 0 0 6 6 6 2 PQQ-like domain PQQ PF01011.21 GAX13239.1 - 0.0047 16.8 1.8 0.46 10.5 0.0 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat TMEM51 PF15345.6 GAX13239.1 - 0.47 10.3 8.9 0.086 12.7 3.4 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 UQ_con PF00179.26 GAX13241.1 - 1.3e-15 57.2 0.0 1.5e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX13241.1 - 0.0049 17.1 0.0 0.0059 16.9 0.0 1.3 1 1 0 1 1 1 1 RWD domain PhyH PF05721.13 GAX13242.1 - 6.7e-14 52.6 0.0 1.4e-13 51.6 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MobA_MobL PF03389.15 GAX13242.1 - 0.075 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 MobA/MobL family MobA_MobL PF03389.15 GAX13243.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 MobA/MobL family DUF5533 PF17685.1 GAX13243.1 - 0.16 12.4 0.1 0.18 12.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5533) Bestrophin PF01062.21 GAX13244.1 - 1.2e-31 110.3 0.1 2.6e-31 109.1 0.1 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel adh_short PF00106.25 GAX13245.1 - 8.3e-24 84.1 0.4 7.4e-21 74.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX13245.1 - 2.4e-14 53.5 0.1 1.6e-10 40.9 0.1 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX13245.1 - 6.8e-11 42.4 0.1 1.4e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX13245.1 - 1.2e-05 24.9 0.1 5.7e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAX13245.1 - 3.6e-05 23.1 0.0 5.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAX13245.1 - 0.0092 15.4 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAX13245.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAX13245.1 - 0.081 12.0 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4033 PF13225.6 GAX13246.1 - 1.8e-26 92.0 0.2 3.5e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) Mad3_BUB1_I PF08311.12 GAX13247.1 - 5.4e-05 23.2 0.9 0.031 14.3 0.1 2.4 1 1 1 2 2 2 2 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 GAX13247.1 - 0.0002 21.9 6.1 0.17 12.8 0.4 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX13247.1 - 0.079 13.3 0.9 1.8 8.9 2.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat SKN1 PF03935.15 GAX13249.1 - 1.9e-66 224.5 10.9 9.7e-51 172.7 1.4 3.4 3 1 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAX13249.1 - 0.0024 17.4 0.1 0.0051 16.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DnaJ PF00226.31 GAX13250.1 - 5.1e-17 61.7 1.2 1e-16 60.8 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain LVIVD PF08309.11 GAX13251.1 - 5.7e-09 35.2 9.4 0.04 13.2 0.0 5.5 5 0 0 5 5 5 3 LVIVD repeat LEAP-2 PF07359.11 GAX13251.1 - 0.1 12.5 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Guanylate_cyc PF00211.20 GAX13252.1 - 9.2e-08 31.9 0.2 3.7e-07 29.9 0.2 1.9 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain zf-RING_2 PF13639.6 GAX13254.1 - 2.6e-05 24.5 10.3 2.9e-05 24.3 8.7 2.0 2 0 0 2 2 1 1 Ring finger domain FANCL_C PF11793.8 GAX13254.1 - 7.6e-05 22.8 6.4 0.00024 21.2 5.7 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain C1_1 PF00130.22 GAX13254.1 - 0.0013 18.6 3.0 0.0013 18.6 3.0 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ANAPC11 PF12861.7 GAX13254.1 - 0.0029 17.6 3.3 0.0078 16.3 3.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 GAX13254.1 - 0.047 14.0 7.8 0.14 12.5 7.8 1.9 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 GAX13254.1 - 0.064 13.1 8.2 0.19 11.6 8.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX13254.1 - 0.39 11.0 6.1 1.3 9.4 6.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 GAX13254.1 - 0.86 9.3 7.8 5 6.8 7.8 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAX13254.1 - 1.8 8.8 12.2 0.32 11.1 7.7 2.2 2 0 0 2 2 2 0 RING-variant domain PHD PF00628.29 GAX13254.1 - 1.9 8.5 11.1 0.71 9.8 7.7 2.2 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_2 PF13923.6 GAX13254.1 - 3.9 7.4 8.7 12 5.8 8.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 GAX13254.1 - 4.6 7.5 6.6 53 4.1 6.4 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF547 PF04784.14 GAX13255.1 - 4.2e-20 72.0 0.0 7.7e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.21 GAX13255.1 - 4.8e-10 39.3 0.0 1.2e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glutaredoxin PF00462.24 GAX13255.1 - 9e-09 35.4 0.0 2.4e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin DUF1664 PF07889.12 GAX13256.1 - 0.69 10.0 2.6 1 9.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 GAX13256.1 - 2.1 8.3 10.7 2.9 7.9 3.0 3.1 3 1 0 3 3 3 0 Prefoldin subunit OmpH PF03938.14 GAX13256.1 - 2.6 8.4 7.4 1.6 9.0 2.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ribosomal_L16 PF00252.18 GAX13257.1 - 2e-36 124.9 0.2 2.5e-36 124.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ge1_WD40 PF16529.5 GAX13258.1 - 4.7e-08 32.4 0.0 8.7e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Fib_alpha PF08702.10 GAX13258.1 - 0.048 13.8 0.2 0.048 13.8 0.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Trimer_CC PF08954.11 GAX13258.1 - 0.051 13.1 1.5 0.17 11.5 1.5 1.9 1 0 0 1 1 1 0 Trimerisation motif SlyX PF04102.12 GAX13258.1 - 0.1 13.2 1.3 0.22 12.2 0.3 2.1 2 0 0 2 2 2 0 SlyX Prominin PF05478.11 GAX13258.1 - 0.14 10.1 4.3 0.032 12.2 1.0 1.5 2 0 0 2 2 2 0 Prominin DUF4611 PF15387.6 GAX13258.1 - 5.5 7.3 7.8 7.7 6.8 1.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) UQ_con PF00179.26 GAX13259.1 - 1.9e-13 50.3 0.0 2.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Biotin_carb_C PF02785.19 GAX13260.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain Sulfotransfer_2 PF03567.14 GAX13261.1 - 0.013 15.4 1.1 0.031 14.2 1.1 1.7 1 1 0 1 1 1 0 Sulfotransferase family zf-CCCH PF00642.24 GAX13263.1 - 0.00099 19.0 6.3 0.00099 19.0 6.3 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GAX13263.1 - 0.039 14.4 18.0 0.083 13.4 4.8 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 GAX13263.1 - 0.041 13.8 2.0 0.1 12.5 2.0 1.7 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 PRP21_like_P PF12230.8 GAX13263.1 - 0.06 13.2 2.9 0.088 12.7 0.2 2.6 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Translin PF01997.16 GAX13264.1 - 1.5e-39 136.1 0.1 5.2e-23 82.1 0.0 2.3 2 0 0 2 2 2 2 Translin family DUF3731 PF12531.8 GAX13264.1 - 0.016 15.0 0.1 4.9 6.9 0.0 2.3 2 0 0 2 2 2 0 DNA-K related protein DUF4296 PF14129.6 GAX13264.1 - 0.12 12.9 0.4 4.6 7.9 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4296) PhyH PF05721.13 GAX13265.1 - 4.3e-28 99.0 0.1 5.5e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-CCCH_2 PF14608.6 GAX13267.1 - 0.018 15.5 2.9 0.018 15.5 2.9 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ank_4 PF13637.6 GAX13268.1 - 1.8e-05 25.2 0.2 0.0073 16.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX13268.1 - 0.013 16.1 0.1 0.48 11.1 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.30 GAX13268.1 - 0.029 14.8 0.3 15 6.2 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 GAX13268.1 - 0.052 14.1 3.1 12 6.9 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat VWA_2 PF13519.6 GAX13269.1 - 1.3e-16 61.1 0.5 7.8e-16 58.7 0.0 2.6 3 1 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 GAX13269.1 - 5.5e-07 29.1 27.2 0.00043 20.0 6.1 4.1 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.14 GAX13269.1 - 0.026 14.3 0.1 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Ssl1-like MCM PF00493.23 GAX13270.1 - 7e-97 322.9 0.0 1.1e-96 322.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX13270.1 - 3.2e-29 101.3 0.0 5.7e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX13270.1 - 5.9e-22 77.9 0.4 1.4e-21 76.7 0.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAX13270.1 - 7.4e-08 32.0 0.3 5.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAX13270.1 - 0.0026 17.6 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 GAX13272.1 - 4.5e-73 245.9 0.1 6.2e-73 245.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13272.1 - 3.2e-42 144.6 0.0 5e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX13272.1 - 1.6e-11 44.1 0.0 4.6e-09 36.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 GAX13272.1 - 0.0036 16.2 2.7 0.007 15.2 2.7 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX13272.1 - 0.0057 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FrhB_FdhB_C PF04432.13 GAX13273.1 - 2.6e-30 105.3 0.0 4.3e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 GAX13273.1 - 1.6e-16 60.2 0.1 3e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term SAP PF02037.27 GAX13275.1 - 2.3e-10 40.0 1.8 4.8e-10 39.0 1.8 1.6 1 0 0 1 1 1 1 SAP domain DLH PF01738.18 GAX13275.1 - 2.1e-09 37.3 0.0 0.0014 18.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Telomere_Sde2_2 PF13297.6 GAX13275.1 - 0.0038 16.8 0.2 0.0081 15.8 0.2 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal RsdA_SigD_bd PF16751.5 GAX13275.1 - 0.019 15.2 0.5 3.5 7.9 0.1 3.0 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region Abhydrolase_6 PF12697.7 GAX13275.1 - 0.053 14.1 0.2 0.1 13.2 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Spo0M PF07070.11 GAX13276.1 - 0.039 13.5 0.0 2.2 7.8 0.0 2.2 1 1 0 1 1 1 0 SpoOM protein SdiA-regulated PF06977.11 GAX13276.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 SdiA-regulated Polysacc_deac_2 PF04748.13 GAX13276.1 - 0.23 10.6 2.1 9.6 5.3 0.0 2.2 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase TFIIA PF03153.13 GAX13276.1 - 2.9 7.8 7.6 3 7.7 7.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CW PF07496.15 GAX13277.1 - 2.4e-29 101.1 22.6 1.3e-14 54.0 8.4 2.6 2 0 0 2 2 2 2 CW-type Zinc Finger PHD PF00628.29 GAX13277.1 - 0.046 13.6 4.9 2.6 8.0 0.6 2.8 2 0 0 2 2 2 0 PHD-finger Ank_5 PF13857.6 GAX13278.1 - 1.6e-08 34.7 0.0 3.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Synaptobrevin PF00957.21 GAX13278.1 - 3e-08 33.3 4.5 3e-08 33.3 4.5 2.0 2 0 0 2 2 2 1 Synaptobrevin Ank_3 PF13606.6 GAX13278.1 - 1.6e-06 28.0 0.0 1.4e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 GAX13278.1 - 2.2e-06 28.2 0.0 4.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX13278.1 - 2.4e-06 27.7 0.0 8e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 GAX13278.1 - 1.3e-05 25.6 0.2 0.012 16.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HAUS6_N PF14661.6 GAX13278.1 - 0.18 11.4 5.7 0.37 10.3 5.7 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Met_10 PF02475.16 GAX13279.1 - 3.7e-46 157.4 0.0 5.3e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 GAX13279.1 - 0.00019 20.8 0.0 0.00025 20.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 GAX13279.1 - 0.00066 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX13279.1 - 0.0065 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX13279.1 - 0.0079 16.9 0.1 0.023 15.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GAX13279.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Methyltransf_31 PF13847.6 GAX13279.1 - 0.057 13.2 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 GAX13279.1 - 0.1 12.3 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 GAX13279.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase VPS13_C PF16909.5 GAX13280.1 - 5e-35 120.9 1.3 8.7e-31 107.1 0.0 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 GAX13280.1 - 1.1e-28 100.7 0.0 8.1e-27 94.5 0.0 3.1 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 GAX13280.1 - 3.7e-20 72.2 0.0 1.8e-19 70.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 GAX13280.1 - 6.8e-18 65.0 0.1 2.3e-16 60.0 0.1 3.1 3 0 0 3 3 3 1 Repeating coiled region of VPS13 SHR-BD PF06650.12 GAX13280.1 - 6.5e-11 42.1 0.0 1.8e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 GAX13280.1 - 1.2e-07 32.0 0.0 3.8e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain FKBP_C PF00254.28 GAX13281.1 - 2.1e-10 40.8 0.0 3.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 GAX13282.1 - 0.092 13.1 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase LRR_4 PF12799.7 GAX13283.1 - 2.3e-13 50.1 15.2 1.8e-05 25.0 0.1 5.5 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAX13283.1 - 2.6e-10 40.1 0.0 0.00041 19.9 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Ubiquitin_2 PF14560.6 GAX13283.1 - 1.6e-09 38.1 0.0 4.2e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain CAP_GLY PF01302.25 GAX13283.1 - 1.1e-08 34.9 0.1 3e-08 33.5 0.1 1.8 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 GAX13283.1 - 5.6e-06 26.0 8.8 0.0023 17.7 0.0 5.4 5 1 1 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 GAX13283.1 - 1.7e-05 24.5 8.5 2.3 8.5 0.1 6.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 GAX13283.1 - 0.32 11.7 15.3 53 5.0 0.4 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat Na_H_Exchanger PF00999.21 GAX13284.1 - 1.1e-40 139.7 39.7 1.4e-40 139.3 39.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MMS19_N PF14500.6 GAX13284.1 - 0.0096 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II COPI_assoc PF08507.10 GAX13285.1 - 2.9e-05 24.1 4.9 9.2e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 COPI associated protein Glyco_trans_2_3 PF13632.6 GAX13285.1 - 0.081 12.8 9.8 0.62 9.9 0.6 2.3 2 0 0 2 2 2 0 Glycosyl transferase family group 2 DUF4131 PF13567.6 GAX13285.1 - 3.2 7.4 8.1 2.1 8.0 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_1 PF00076.22 GAX13286.1 - 5e-18 64.7 0.0 7.3e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UDPGP PF01704.18 GAX13287.1 - 1.7e-121 405.8 0.0 2.2e-121 405.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 GAX13287.1 - 2e-32 111.8 0.0 3.6e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAX13287.1 - 5.7e-25 87.7 0.0 1.2e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAX13287.1 - 2.8e-09 37.5 0.1 8.6e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GAX13287.1 - 5.8e-05 23.2 0.0 0.00018 21.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Asp_Arg_Hydrox PF05118.15 GAX13288.1 - 1.4e-19 70.4 0.0 2.1e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase ATG13 PF10033.9 GAX13289.1 - 1.1e-15 58.0 0.3 6.9e-10 39.0 0.2 2.6 1 1 1 2 2 2 2 Autophagy-related protein 13 His_biosynth PF00977.21 GAX13290.1 - 8e-31 107.3 0.0 1.1e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PRAI PF00697.22 GAX13290.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Ribul_P_3_epim PF00834.19 GAX13290.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family HEAT PF02985.22 GAX13292.1 - 1e-13 50.2 9.2 0.0033 17.6 0.1 6.3 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 GAX13292.1 - 3.9e-07 30.4 10.1 0.069 13.7 0.0 6.2 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 GAX13292.1 - 4e-06 27.1 8.8 0.039 14.3 0.1 5.1 4 1 0 5 5 5 3 HEAT repeats Vac14_Fab1_bd PF12755.7 GAX13292.1 - 0.001 19.6 0.0 0.018 15.7 0.0 2.8 2 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAX13292.1 - 0.0088 15.6 0.9 3.9 7.0 0.0 3.7 3 1 1 4 4 4 1 CLASP N terminal IFRD PF05004.13 GAX13292.1 - 0.013 14.6 0.1 0.31 10.1 0.0 2.7 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) PUL PF08324.11 GAX13292.1 - 0.034 13.4 0.0 9.2 5.4 0.0 2.4 2 0 0 2 2 2 0 PUL domain PaaX_C PF08223.11 GAX13293.1 - 0.099 12.9 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain SNase PF00565.17 GAX13294.1 - 1.3e-36 125.4 0.0 4.2e-09 36.8 0.0 6.9 5 2 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 GAX13294.1 - 2.8e-12 46.7 0.0 1.1e-11 44.9 0.0 1.9 2 0 0 2 2 2 1 Tudor domain Agenet PF05641.12 GAX13294.1 - 0.022 15.2 0.0 0.4 11.2 0.0 2.8 3 0 0 3 3 3 0 Agenet domain FA_desaturase PF00487.24 GAX13295.1 - 1.3e-33 117.0 4.1 1.3e-33 117.0 4.1 1.5 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAX13295.1 - 4.2e-09 36.4 0.0 9.2e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PPR PF01535.20 GAX13296.1 - 2.8e-20 71.1 4.2 2.3e-06 27.5 0.0 8.8 8 1 0 8 8 8 2 PPR repeat PPR_2 PF13041.6 GAX13296.1 - 8.1e-20 70.8 0.2 2.9e-06 27.4 0.0 5.7 5 1 0 5 5 5 3 PPR repeat family PPR_1 PF12854.7 GAX13296.1 - 2.7e-18 65.3 0.9 8.3e-07 28.6 0.0 6.2 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 GAX13296.1 - 6.6e-15 54.9 0.0 0.00059 19.9 0.0 5.3 4 2 1 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX13296.1 - 3.8e-05 23.1 0.4 0.0019 17.6 0.1 3.2 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP Wzy_C_2 PF11846.8 GAX13296.1 - 0.0017 18.3 0.1 15 5.4 0.0 3.4 3 0 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal PqqD PF05402.12 GAX13296.1 - 0.063 13.6 0.2 16 5.9 0.0 4.1 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) RTP1_C1 PF10363.9 GAX13296.1 - 0.067 13.4 0.1 5.8 7.1 0.0 3.1 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 PhageMin_Tail PF10145.9 GAX13296.1 - 0.096 12.5 2.3 2.4 8.0 0.6 3.1 3 1 0 3 3 3 0 Phage-related minor tail protein Mito_carr PF00153.27 GAX13297.1 - 8.9e-36 121.7 1.9 1.5e-12 47.3 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein WBP-1 PF11669.8 GAX13298.1 - 0.00096 19.7 0.0 0.028 15.1 0.0 2.3 2 0 0 2 2 2 1 WW domain-binding protein 1 Mucin PF01456.17 GAX13298.1 - 0.0027 17.7 0.0 0.006 16.6 0.0 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein CYSTM PF12734.7 GAX13299.1 - 0.0005 20.3 3.8 0.0011 19.2 2.1 2.5 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance WBP-1 PF11669.8 GAX13299.1 - 0.0041 17.7 0.6 0.21 12.3 0.0 2.3 2 0 0 2 2 2 1 WW domain-binding protein 1 ketoacyl-synt PF00109.26 GAX13300.1 - 2.1e-38 132.4 2.3 2.4e-38 132.2 1.6 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAX13300.1 - 4e-31 107.5 0.1 6.5e-30 103.6 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAX13300.1 - 0.0078 15.6 0.3 0.047 13.1 0.2 2.3 2 1 1 3 3 3 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 GAX13300.1 - 0.035 14.5 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 GAX13301.1 - 6.9e-21 74.2 1.7 1.5e-20 73.1 1.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAX13301.1 - 3.2e-08 33.6 0.0 7.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAX13301.1 - 4.3e-05 23.1 0.0 8.7e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAX13301.1 - 0.0032 18.5 0.0 0.47 11.5 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX13301.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ACP_syn_III_C PF08541.10 GAX13302.1 - 7.9e-40 134.9 0.1 9.6e-39 131.5 0.1 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 GAX13302.1 - 7.4e-26 89.8 1.4 6.6e-25 86.8 0.3 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 GAX13302.1 - 4.6e-06 26.2 0.1 0.00016 21.1 0.0 2.3 2 1 1 3 3 3 1 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.15 GAX13302.1 - 0.00014 21.9 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Thiolase_C PF02803.18 GAX13302.1 - 0.0016 18.1 0.6 0.017 14.7 0.3 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain Chal_sti_synt_N PF00195.19 GAX13302.1 - 0.085 12.3 0.1 0.25 10.7 0.1 1.7 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain LEA_3 PF03242.13 GAX13303.1 - 0.051 14.3 0.7 0.13 13.0 0.7 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein Vps54 PF07928.12 GAX13304.1 - 2.6e-36 125.0 0.8 6.3e-36 123.8 0.8 1.7 1 0 0 1 1 1 1 Vps54-like protein Peptidase_M13_N PF05649.13 GAX13305.1 - 3.6e-71 240.9 0.0 6.3e-42 144.6 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 GAX13305.1 - 6.5e-67 225.1 0.0 2.3e-66 223.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M13 PSK_trans_fac PF07704.11 GAX13305.1 - 0.039 14.7 1.0 0.14 13.0 0.0 2.3 2 0 0 2 2 2 0 Rv0623-like transcription factor LpxC PF03331.13 GAX13305.1 - 0.1 12.1 0.3 0.19 11.2 0.3 1.4 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase DUF4574 PF15141.6 GAX13305.1 - 0.14 12.1 0.2 0.49 10.3 0.2 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 STT3 PF02516.14 GAX13306.1 - 1.2e-49 169.5 26.6 1e-33 117.1 8.5 3.1 3 0 0 3 3 3 3 Oligosaccharyl transferase STT3 subunit FA_desaturase PF00487.24 GAX13307.1 - 0.037 13.9 1.1 0.039 13.8 1.1 1.0 1 0 0 1 1 1 0 Fatty acid desaturase Conotoxin PF02950.17 GAX13307.1 - 0.062 14.3 0.1 7.6 7.6 0.1 2.1 2 0 0 2 2 2 0 Conotoxin zf-RING_2 PF13639.6 GAX13308.1 - 5.4e-08 33.0 6.0 1.2e-07 31.9 6.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX13308.1 - 3e-05 23.6 4.0 7.8e-05 22.3 4.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAX13308.1 - 0.00012 22.0 3.5 0.00025 21.0 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX13308.1 - 0.00023 21.0 6.8 0.0004 20.2 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX13308.1 - 0.0009 19.5 2.7 0.0019 18.4 2.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAX13308.1 - 0.0041 16.9 5.6 0.0079 16.0 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX13308.1 - 0.0065 16.3 6.6 0.014 15.2 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CUE PF02845.16 GAX13308.1 - 0.043 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 CUE domain zf-RING_5 PF14634.6 GAX13308.1 - 0.15 12.1 5.8 0.44 10.5 5.9 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX13308.1 - 0.19 11.8 3.4 0.61 10.2 3.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GAGA PF09237.11 GAX13308.1 - 0.24 11.3 0.1 0.24 11.3 0.1 1.8 2 0 0 2 2 1 0 GAGA factor zf-UDP PF14569.6 GAX13308.1 - 0.26 11.4 2.0 0.53 10.4 2.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger PHD PF00628.29 GAX13308.1 - 1 9.3 4.1 2 8.4 4.1 1.5 1 0 0 1 1 1 0 PHD-finger BSP_II PF05432.11 GAX13308.1 - 1.2 8.8 4.5 2.1 8.0 4.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Prok-RING_4 PF14447.6 GAX13308.1 - 3.4 7.6 6.7 6.5 6.7 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Peptidase_M16_M PF16187.5 GAX13309.1 - 1.2e-55 188.8 0.2 1.5e-32 113.0 0.0 2.3 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX13309.1 - 7.3e-31 107.2 0.0 1.5e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX13309.1 - 2.4e-22 79.8 0.0 2.6e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain HMG_box PF00505.19 GAX13311.1 - 1.3e-14 54.3 5.4 1.3e-08 35.2 5.3 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX13311.1 - 1.3e-10 41.7 5.8 5e-08 33.4 3.4 2.5 2 1 0 2 2 2 2 HMG-box domain Retrotrans_gag PF03732.17 GAX13311.1 - 0.093 13.0 1.7 0.13 12.5 0.6 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein 2OG-FeII_Oxy_3 PF13640.6 GAX13312.1 - 2.2e-11 44.5 0.0 3.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rep_fac-A_C PF08646.10 GAX13314.1 - 3e-33 114.6 0.0 7.8e-33 113.3 0.0 1.8 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GAX13314.1 - 1e-28 99.1 1.8 8.6e-27 92.9 0.0 3.6 4 0 0 4 4 4 1 Replication protein A OB domain Rep-A_N PF04057.12 GAX13314.1 - 6.7e-22 77.4 1.3 1.2e-21 76.6 1.3 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 GAX13314.1 - 1.1e-14 54.2 0.5 1.3e-08 34.7 0.0 4.5 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain POT1 PF02765.17 GAX13314.1 - 0.00051 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 CDC24_OB3 PF17244.2 GAX13314.1 - 0.017 14.8 0.1 0.48 10.1 0.1 2.6 2 1 0 2 2 2 0 Cell division control protein 24, OB domain 3 zf-RRN7 PF11781.8 GAX13314.1 - 0.08 12.7 1.3 0.15 11.8 1.3 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TPP1 PF10341.9 GAX13314.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD POT1 PF02765.17 GAX13315.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 Spc7 PF08317.11 GAX13316.1 - 0.017 14.0 10.2 0.025 13.5 10.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Pro_isomerase PF00160.21 GAX13316.1 - 0.021 15.1 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zein-binding PF04576.15 GAX13316.1 - 0.024 14.9 2.0 0.024 14.9 2.0 2.5 1 1 1 2 2 2 0 Zein-binding FapA PF03961.13 GAX13316.1 - 0.061 11.9 2.9 0.095 11.3 2.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A MctB PF11382.8 GAX13316.1 - 0.28 10.8 8.5 0.44 10.2 8.5 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB FAM184 PF15665.5 GAX13316.1 - 0.3 10.8 19.2 0.33 10.7 6.8 2.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B GAS PF13851.6 GAX13316.1 - 0.32 10.3 15.0 0.53 9.6 14.5 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 GAX13316.1 - 4.3 6.3 14.2 7.9 5.5 14.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 GAX13316.1 - 6.2 5.7 15.9 9.4 5.1 15.6 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 GAX13316.1 - 6.9 6.1 14.9 9.4 5.7 14.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 GAX13316.1 - 7 6.7 17.5 5.8 7.0 0.6 3.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Chloroa_b-bind PF00504.21 GAX13317.1 - 1.1e-34 120.3 0.0 1.5e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX13318.1 - 1.8e-29 103.4 0.0 2.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Peptidase_S10 PF00450.22 GAX13319.1 - 5.2e-86 289.7 0.0 6e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CUE PF02845.16 GAX13320.1 - 1.7e-05 24.4 0.0 6.4e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 CUE domain zf-RING_2 PF13639.6 GAX13321.1 - 2.8e-08 33.9 11.8 2.8e-08 33.9 11.8 2.2 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 GAX13321.1 - 3.5e-07 30.4 9.3 3.5e-07 30.4 9.3 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX13321.1 - 3.6e-07 29.9 12.0 7.5e-07 28.9 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX13321.1 - 4e-06 26.6 9.9 7.3e-06 25.8 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX13321.1 - 0.00011 21.9 6.4 0.00026 20.8 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX13321.1 - 0.00034 20.3 6.1 0.00079 19.1 6.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GAX13321.1 - 0.0016 18.4 5.4 0.0059 16.6 4.7 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX13321.1 - 0.0051 16.4 7.3 0.0094 15.5 7.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GAX13321.1 - 0.016 15.3 8.1 0.066 13.2 8.4 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAX13321.1 - 0.036 14.0 8.2 0.071 13.1 8.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3H2C3 PF17122.5 GAX13321.1 - 0.077 13.1 3.7 0.22 11.6 3.7 1.8 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 GAX13321.1 - 0.19 11.7 9.3 0.38 10.7 9.3 1.5 1 0 0 1 1 1 0 PHD-finger ADK_lid PF05191.14 GAX13321.1 - 0.99 9.4 5.0 18 5.4 1.9 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid Prok-RING_4 PF14447.6 GAX13321.1 - 2.9 7.8 9.3 10 6.1 8.3 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 GAX13321.1 - 3.8 7.8 12.2 7.3 6.8 9.0 2.8 3 1 0 3 3 3 0 FANCL C-terminal domain zf-RING_4 PF14570.6 GAX13321.1 - 3.9 7.4 9.7 8.7 6.2 9.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 GAX13321.1 - 4.7 7.4 13.3 2.6 8.3 10.2 2.1 2 0 0 2 2 2 0 RING-variant domain zf-C2H2_2 PF12756.7 GAX13322.1 - 5.9e-26 90.7 1.1 5.9e-26 90.7 1.1 2.5 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAX13322.1 - 0.013 16.3 3.3 0.12 13.2 2.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAX13322.1 - 0.06 13.8 6.8 0.35 11.4 3.8 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Nop25 PF09805.9 GAX13322.1 - 0.12 12.8 6.6 0.93 10.0 0.4 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) zf-met PF12874.7 GAX13322.1 - 1.7 9.2 10.0 0.7 10.4 2.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAX13322.1 - 4.9 7.6 17.2 1.1 9.6 2.8 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C2 PF00168.30 GAX13323.1 - 1.7e-13 50.7 0.0 5.1e-12 46.0 0.0 2.5 1 1 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 GAX13323.1 - 0.00025 21.6 0.5 0.2 12.3 0.0 4.0 4 0 0 4 4 4 1 Putative heavy-metal-binding WD40 PF00400.32 GAX13324.1 - 7.5e-30 102.5 13.2 8.8e-09 35.9 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX13324.1 - 1.3e-08 35.0 0.0 0.022 15.1 0.0 4.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX13324.1 - 0.00038 19.5 0.0 0.32 9.9 0.0 3.5 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GAX13324.1 - 0.18 10.5 0.0 0.91 8.2 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like CPP1-like PF11833.8 GAX13325.1 - 1.9e-13 50.5 0.8 6.4e-13 48.8 0.8 1.8 1 1 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TAFII28 PF04719.14 GAX13326.1 - 1.9e-07 31.0 0.0 5.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Ion_trans_2 PF07885.16 GAX13327.1 - 3.4e-17 62.2 13.9 9.7e-09 35.1 3.1 2.6 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 GAX13327.1 - 0.015 14.5 13.1 0.082 12.1 1.9 2.4 2 0 0 2 2 2 0 Ion transport protein SH2_2 PF14633.6 GAX13330.1 - 6.6e-55 185.8 0.0 1.5e-54 184.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 GAX13330.1 - 6e-20 71.5 0.0 1.3e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 GAX13330.1 - 9.8e-14 51.8 0.7 5e-13 49.5 0.7 2.2 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.23 GAX13330.1 - 3e-10 40.3 0.5 6.6e-10 39.2 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 GAX13330.1 - 3.3e-10 40.0 0.0 8e-09 35.4 0.0 2.6 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_3 PF12836.7 GAX13330.1 - 4.9e-05 23.5 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2 PF00017.24 GAX13330.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 SH2 domain IBB PF01749.20 GAX13331.1 - 9.6e-06 26.0 0.9 2.2e-05 24.8 0.9 1.6 1 0 0 1 1 1 1 Importin beta binding domain PEP-utilizers_C PF02896.18 GAX13332.1 - 2.5e-77 259.9 0.0 3.8e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 GAX13332.1 - 7.1e-56 189.8 0.0 2.9e-35 122.1 0.0 3.2 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 GAX13332.1 - 1.3e-24 85.7 0.8 3.1e-24 84.5 0.1 2.0 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain NitrOD5 PF11537.8 GAX13332.1 - 0.0025 17.9 0.0 0.62 10.2 0.0 2.6 2 0 0 2 2 2 2 Nitrosopumilus output domain 5 PerC PF06069.11 GAX13332.1 - 0.03 14.6 0.0 3.9 7.8 0.0 2.7 2 0 0 2 2 2 0 PerC transcriptional activator NatB_MDM20 PF09797.9 GAX13333.1 - 2.2e-42 145.4 0.0 4.1e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit NARP1 PF12569.8 GAX13333.1 - 2.3e-07 30.1 1.1 7.7e-07 28.4 0.3 2.0 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 GAX13333.1 - 0.00017 22.2 0.6 0.0039 17.9 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX13333.1 - 0.026 14.6 0.0 0.026 14.6 0.0 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX13333.1 - 0.027 15.0 0.0 0.027 15.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX13333.1 - 0.032 14.9 0.2 0.21 12.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX13333.1 - 0.039 14.6 0.1 0.47 11.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX13333.1 - 0.071 13.4 3.3 0.34 11.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX13333.1 - 6.7 7.0 11.7 13 6.1 0.0 4.8 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 BCAS2 PF05700.11 GAX13334.1 - 6.5e-28 97.8 15.2 9.4e-28 97.3 15.2 1.2 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF3584 PF12128.8 GAX13334.1 - 0.019 12.5 12.5 0.02 12.4 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1465 PF07323.12 GAX13334.1 - 0.052 13.4 4.5 0.096 12.5 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Cep57_CLD PF14073.6 GAX13334.1 - 0.12 12.3 14.7 0.041 13.9 11.7 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 TMF_DNA_bd PF12329.8 GAX13334.1 - 0.49 10.4 14.2 8.9 6.4 12.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4094 PF13334.6 GAX13334.1 - 0.75 10.2 4.9 1.7 9.2 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Tim17 PF02466.19 GAX13335.1 - 4.2e-06 27.1 0.0 9.1e-05 22.8 0.0 2.4 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF3938 PF13074.6 GAX13335.1 - 0.076 13.3 0.4 0.24 11.6 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) His_Phos_1 PF00300.22 GAX13336.1 - 9.7e-35 120.0 0.0 1.8e-28 99.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 GAX13337.1 - 3.7e-64 217.2 0.0 4.8e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hyr1 PF15789.5 GAX13337.1 - 0.063 12.8 0.7 0.17 11.5 0.7 1.7 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 HSP70 PF00012.20 GAX13338.1 - 3.8e-105 352.3 1.3 1.8e-104 350.1 0.0 2.4 1 1 1 2 2 2 1 Hsp70 protein SPARC_Ca_bdg PF10591.9 GAX13338.1 - 0.028 14.8 0.3 0.069 13.5 0.3 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region AbiEi_3_N PF17194.4 GAX13338.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain EF-hand_1 PF00036.32 GAX13339.1 - 9.1e-07 28.0 0.8 0.093 12.3 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 GAX13339.1 - 1.1e-06 27.8 1.9 0.028 13.9 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 GAX13339.1 - 9.1e-06 26.0 0.4 0.035 14.5 0.1 3.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX13339.1 - 1.7e-05 24.6 0.0 0.065 13.1 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX13339.1 - 0.0056 16.5 1.3 2.7 8.2 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain VCBS PF13517.6 GAX13339.1 - 0.21 12.2 0.8 28 5.4 0.2 3.5 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AstE_AspA PF04952.14 GAX13340.1 - 2e-29 102.6 0.0 2.9e-27 95.5 0.0 2.4 2 1 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family PDZ PF00595.24 GAX13341.1 - 0.00049 20.4 0.1 0.0013 19.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX13341.1 - 0.0031 17.8 1.5 0.006 16.9 0.1 2.2 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 GAX13341.1 - 0.0086 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain EF-hand_12 PF17901.1 GAX13341.1 - 0.062 13.8 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 EF-hand fold domain STT3 PF02516.14 GAX13343.1 - 6.4e-55 187.0 24.4 4.4e-31 108.4 8.2 3.1 3 0 0 3 3 3 3 Oligosaccharyl transferase STT3 subunit DUF1279 PF06916.13 GAX13344.1 - 3.6e-12 46.6 0.3 7.4e-12 45.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) HECT PF00632.25 GAX13346.1 - 4.7e-37 128.1 0.1 1.3e-33 116.8 0.1 2.3 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 GAX13346.1 - 3.1e-36 124.1 1.1 3.4e-16 59.4 0.1 4.6 4 0 0 4 4 4 3 SPRY domain UBA PF00627.31 GAX13346.1 - 3.9e-09 36.2 0.2 1.4e-07 31.3 0.0 2.9 2 0 0 2 2 2 1 UBA/TS-N domain MIB_HERC2 PF06701.13 GAX13346.1 - 0.0055 16.9 1.8 0.04 14.2 1.8 2.5 1 1 0 1 1 1 1 Mib_herc2 HRI1 PF16815.5 GAX13347.1 - 4.3e-08 33.2 0.0 7.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Protein HRI1 DUF179 PF02622.15 GAX13348.1 - 2.6e-05 24.2 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 DUF4746 PF15928.5 GAX13349.1 - 0.17 11.3 7.9 0.35 10.3 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Elong-fact-P_C PF09285.11 GAX13350.1 - 4.9e-21 74.2 1.1 1.1e-20 73.2 0.1 2.1 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 GAX13350.1 - 1.8e-19 69.5 0.3 4.3e-19 68.3 0.3 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 GAX13350.1 - 1.3e-16 60.3 0.7 2.8e-16 59.3 0.2 1.8 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Gal-bind_lectin PF00337.22 GAX13350.1 - 0.068 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Galactoside-binding lectin PEP-utilizers PF00391.23 GAX13350.1 - 0.16 11.7 0.2 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain ABC_tran PF00005.27 GAX13351.1 - 1.5e-49 168.0 7.4 7.2e-25 88.1 0.0 3.6 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX13351.1 - 6.1e-19 67.8 5.6 2.1e-18 66.1 1.7 5.6 5 0 0 5 5 5 2 ABC transporter AAA_21 PF13304.6 GAX13351.1 - 3e-12 47.0 7.2 0.006 16.4 0.1 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX13351.1 - 2.6e-07 31.2 0.1 0.037 14.4 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 GAX13351.1 - 2.8e-07 30.2 10.9 0.003 17.0 0.1 4.4 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 GAX13351.1 - 1.4e-06 28.9 0.5 0.14 12.7 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 GAX13351.1 - 9.4e-06 25.8 0.0 0.057 13.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAX13351.1 - 1.1e-05 25.4 0.8 0.095 12.6 0.0 3.3 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 GAX13351.1 - 1.7e-05 24.5 0.1 0.027 14.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX13351.1 - 2.5e-05 24.6 3.2 0.0072 16.6 0.0 3.7 3 2 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 GAX13351.1 - 2.8e-05 24.2 1.1 0.062 13.4 0.0 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAX13351.1 - 3.9e-05 23.9 9.2 0.033 14.4 0.0 3.9 4 1 0 4 4 3 2 AAA domain AAA_14 PF13173.6 GAX13351.1 - 0.00011 22.2 0.1 0.24 11.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAX13351.1 - 0.00011 22.6 0.0 0.98 9.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAX13351.1 - 0.00012 21.9 0.2 0.48 10.1 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAX13351.1 - 0.0004 20.0 0.0 0.016 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAX13351.1 - 0.00041 20.0 0.9 1.1 8.9 0.0 3.2 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 GAX13351.1 - 0.00065 19.7 0.9 0.84 9.5 0.0 3.5 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_30 PF13604.6 GAX13351.1 - 0.0013 18.5 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX13351.1 - 0.0015 17.9 0.1 0.32 10.2 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 GAX13351.1 - 0.0063 16.0 0.1 0.32 10.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 GAX13351.1 - 0.0082 16.1 2.5 0.42 10.5 0.0 3.2 3 1 0 3 3 2 1 NACHT domain RNA_helicase PF00910.22 GAX13351.1 - 0.0088 16.4 0.0 1.6 9.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase SRP54 PF00448.22 GAX13351.1 - 0.01 15.4 0.2 0.68 9.5 0.0 3.0 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 GAX13351.1 - 0.011 15.5 0.1 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Cytidylate kinase TsaE PF02367.17 GAX13351.1 - 0.016 15.2 0.1 2.3 8.2 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 GAX13351.1 - 0.032 14.0 0.1 3.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain ATP-synt_ab PF00006.25 GAX13351.1 - 0.035 13.7 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 GAX13351.1 - 0.057 13.2 0.1 0.74 9.5 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 GAX13351.1 - 0.089 13.3 0.0 0.089 13.3 0.0 5.8 5 2 0 5 5 4 0 AAA domain PduV-EutP PF10662.9 GAX13351.1 - 0.1 12.3 0.1 6.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 GAX13351.1 - 0.18 10.8 3.5 1.9 7.4 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 GAX13351.1 - 0.22 11.7 3.9 1.7 8.9 0.0 3.4 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAX13351.1 - 0.24 11.4 0.0 0.24 11.4 0.0 4.2 4 1 0 4 4 2 0 Dynamin family HrpA_pilin PF09589.10 GAX13351.1 - 3.4 8.4 7.2 9.9 7.0 1.5 3.2 2 0 0 2 2 2 0 HrpA pilus formation protein Enolase_C PF00113.22 GAX13352.1 - 1.6e-132 441.3 0.0 2e-132 440.9 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAX13352.1 - 1.4e-57 193.5 0.3 2.5e-57 192.7 0.3 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAX13352.1 - 2.8e-09 36.9 0.0 1.2e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAX13352.1 - 4.1e-05 22.9 0.1 4.1e-05 22.9 0.1 1.9 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus MTH865 PF07747.11 GAX13352.1 - 0.085 12.6 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 MTH865-like family Tic110 PF16940.5 GAX13353.1 - 1e-14 54.0 13.2 2e-06 26.6 0.2 3.9 3 1 1 4 4 4 3 Chloroplast envelope transporter LcrG PF07216.12 GAX13353.1 - 0.051 13.5 6.7 0.91 9.5 0.1 3.9 3 0 0 3 3 3 0 LcrG protein Jag_N PF14804.6 GAX13353.1 - 0.099 13.0 0.2 18 5.8 0.0 3.6 3 0 0 3 3 3 0 Jag N-terminus Phage_TAC_3 PF06896.11 GAX13353.1 - 0.11 13.0 6.3 0.52 10.9 0.1 4.2 4 0 0 4 4 4 0 Phage tail assembly chaperone proteins, TAC ArdA PF07275.11 GAX13353.1 - 0.76 10.4 3.0 3.2 8.3 0.5 2.9 2 1 0 2 2 2 0 Antirestriction protein (ArdA) ZapA PF05164.13 GAX13353.1 - 2.1 8.8 4.9 3.6 8.1 0.5 3.2 2 1 0 2 2 2 0 Cell division protein ZapA DUF285 PF03382.14 GAX13354.1 - 1.7e-95 315.1 35.3 1.1e-27 96.2 5.4 4.2 2 1 2 4 4 4 4 Mycoplasma protein of unknown function, DUF285 DASH_Dam1 PF08653.10 GAX13354.1 - 0.086 12.7 2.5 1.2 9.0 0.3 3.7 3 1 2 5 5 5 0 DASH complex subunit Dam1 DEAD PF00270.29 GAX13355.1 - 2.3e-38 131.7 0.0 1.3e-37 129.2 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX13355.1 - 2.9e-25 88.8 0.0 2.2e-22 79.5 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAX13355.1 - 1.2e-11 44.6 0.0 2.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAX13355.1 - 9.1e-09 35.5 0.0 3.4e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit EBV-NA3 PF05009.12 GAX13355.1 - 0.033 13.7 2.7 0.069 12.7 2.7 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) ERCC3_RAD25_C PF16203.5 GAX13355.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_11 PF13086.6 GAX13355.1 - 0.65 9.7 0.0 0.65 9.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain Cpn60_TCP1 PF00118.24 GAX13356.1 - 2.1e-137 458.7 3.1 2.4e-137 458.5 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Hydrolase PF00702.26 GAX13356.1 - 0.011 16.1 0.3 0.056 13.7 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 GAX13357.1 - 1.6e-38 130.5 2.7 2e-17 62.9 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein TPP1 PF10341.9 GAX13359.1 - 0.022 14.7 0.4 0.55 10.2 0.0 2.9 3 0 0 3 3 3 0 Shelterin complex subunit, TPP1/ACD VEFS-Box PF09733.9 GAX13359.1 - 0.56 10.0 3.6 1.3 8.8 3.6 1.6 1 0 0 1 1 1 0 VEFS-Box of polycomb protein AA_kinase PF00696.28 GAX13360.1 - 1.8e-35 122.7 0.0 8.3e-35 120.5 0.0 2.1 1 1 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 GAX13360.1 - 1.6e-31 109.6 0.4 1.4e-29 103.2 0.0 3.0 2 1 0 2 2 2 1 Homoserine dehydrogenase ACT_7 PF13840.6 GAX13360.1 - 1.8e-11 43.6 3.3 8.7e-07 28.6 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 GAX13360.1 - 2.1e-10 40.2 2.8 7.5e-06 25.6 0.1 3.0 2 0 0 2 2 2 2 ACT domain NAD_binding_3 PF03447.16 GAX13360.1 - 5.5e-08 33.5 0.3 3.5e-07 30.9 0.0 2.7 3 1 0 3 3 3 1 Homoserine dehydrogenase, NAD binding domain ACT_6 PF13740.6 GAX13360.1 - 0.0026 17.7 3.0 1.4 8.9 0.1 4.1 4 0 0 4 4 4 1 ACT domain S-methyl_trans PF02574.16 GAX13360.1 - 0.0035 17.2 0.0 0.028 14.2 0.0 2.2 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Rab15_effector PF15208.6 GAX13360.1 - 0.098 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Rab15 effector Sulfotransfer_1 PF00685.27 GAX13361.1 - 1.2e-07 31.5 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX13361.1 - 2.5e-05 24.8 0.4 5.9e-05 23.5 0.4 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 GAX13361.1 - 0.0025 17.8 0.1 0.004 17.1 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 GAX13362.1 - 3.8e-21 76.2 0.1 6.9e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family FmdA_AmdA PF03069.15 GAX13363.1 - 6e-170 565.0 0.0 7e-170 564.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family KH_1 PF00013.29 GAX13365.1 - 1.7e-28 98.3 0.0 3.4e-13 49.2 0.0 2.7 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 GAX13365.1 - 0.0008 19.2 0.0 0.15 11.9 0.1 2.6 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 GAX13365.1 - 0.03 14.2 0.1 6.5 6.7 0.0 2.7 3 0 0 3 3 3 0 KH domain Raf1_HTH PF18579.1 GAX13365.1 - 0.078 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain PRP9_N PF16958.5 GAX13365.1 - 0.13 12.2 2.7 0.29 11.2 2.7 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus GLTSCR1 PF15249.6 GAX13365.1 - 0.25 11.8 2.7 0.2 12.1 0.5 1.9 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein zf-AN1 PF01428.16 GAX13365.1 - 0.57 10.4 5.2 1.5 9.1 5.2 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger PrsW-protease PF13367.6 GAX13366.1 - 2.8e-05 23.7 1.1 2.8e-05 23.7 1.1 3.5 3 1 1 4 4 4 2 PrsW family intramembrane metalloprotease NPR3 PF03666.13 GAX13366.1 - 0.5 9.1 4.9 9 5.0 3.1 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 AA_permease_C PF13906.6 GAX13366.1 - 9.8 6.3 7.7 0.76 9.9 1.7 2.2 2 0 0 2 2 2 0 C-terminus of AA_permease LRAT PF04970.13 GAX13367.1 - 0.0033 17.7 1.4 0.015 15.6 1.4 2.1 1 1 0 1 1 1 1 Lecithin retinol acyltransferase DUF3847 PF12958.7 GAX13368.1 - 0.07 13.2 0.2 0.86 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Lsr2 PF11774.8 GAX13368.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 Lsr2 DUF3972 PF13118.6 GAX13369.1 - 0.012 16.1 0.1 0.019 15.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) TolA_bind_tri PF16331.5 GAX13369.1 - 0.016 15.2 1.6 0.016 15.2 1.6 2.0 1 1 1 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 GAX13369.1 - 0.018 14.8 1.2 0.018 14.8 1.2 2.5 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.18 GAX13369.1 - 0.027 14.7 0.7 0.067 13.4 0.7 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 GAX13369.1 - 0.029 14.8 4.0 0.029 14.8 4.0 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DUF5320 PF17253.2 GAX13369.1 - 0.058 14.5 0.9 0.11 13.6 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) bZIP_2 PF07716.15 GAX13369.1 - 0.065 13.3 7.5 0.17 12.0 7.5 1.7 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 GAX13369.1 - 0.18 12.0 10.5 0.39 10.9 10.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 GAX13369.1 - 0.2 12.3 3.9 0.22 12.2 2.7 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Cep57_MT_bd PF06657.13 GAX13369.1 - 0.33 11.4 3.7 0.39 11.2 1.8 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 UBA PF00627.31 GAX13369.1 - 0.7 9.9 2.8 9.9 6.2 0.1 2.6 2 0 0 2 2 2 0 UBA/TS-N domain Atg14 PF10186.9 GAX13369.1 - 0.95 8.5 8.8 1.3 8.0 8.5 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPD5 PF18799.1 GAX13369.1 - 1.6 9.1 5.9 2.5 8.5 5.5 1.5 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 5 Spc24 PF08286.11 GAX13369.1 - 3.5 7.9 5.5 2.5 8.4 3.5 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Globin PF00042.22 GAX13370.1 - 1.4e-12 48.2 0.0 1.8e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Globin HSF_DNA-bind PF00447.17 GAX13371.1 - 6.4e-22 78.0 0.1 1.2e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding CBM_6 PF03422.15 GAX13374.1 - 9.3e-32 110.0 0.0 8.7e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX13374.1 - 7.8e-12 45.3 0.0 8.4e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX13374.1 - 0.00012 22.4 0.0 0.061 13.6 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) DnaJ PF00226.31 GAX13375.1 - 1.2e-09 38.1 0.1 7.2e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Pkinase_Tyr PF07714.17 GAX13376.1 - 9.4e-29 100.5 0.0 7.5e-28 97.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX13376.1 - 1e-27 97.2 0.0 2.4e-27 96.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX13376.1 - 0.0058 15.5 0.0 0.0074 15.1 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase HSF_DNA-bind PF00447.17 GAX13377.1 - 5.3e-21 75.0 0.0 7.6e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Ank_4 PF13637.6 GAX13379.1 - 6.5e-13 48.9 0.0 1e-06 29.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX13379.1 - 2.5e-10 40.8 0.0 9.8e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX13379.1 - 2.4e-08 33.6 0.0 1.8e-06 27.8 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAX13379.1 - 3.7e-07 30.3 0.0 7.4e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GAX13379.1 - 0.00011 22.5 0.0 0.00029 21.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX13380.1 - 6.1e-19 68.4 7.6 1.1e-10 41.9 0.9 1.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX13380.1 - 1.6e-11 44.5 0.9 1.8e-06 28.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX13380.1 - 1.4e-07 31.6 1.0 1.8e-05 24.9 0.5 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 GAX13380.1 - 3.6e-07 30.0 0.4 2.1e-06 27.6 0.1 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 GAX13380.1 - 3.8e-06 27.1 0.9 3.4e-05 24.0 0.2 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Lipoprotein_22 PF17294.2 GAX13380.1 - 0.048 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised lipoprotein family HATPase_c PF02518.26 GAX13382.1 - 1.9e-20 73.4 0.1 4.5e-20 72.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX13382.1 - 7.4e-11 42.2 0.0 2.4e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX13382.1 - 5.7e-09 35.9 0.6 1.6e-08 34.5 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE PF03924.13 GAX13382.1 - 0.0012 18.9 0.0 0.0035 17.3 0.0 1.7 2 0 0 2 2 2 1 CHASE domain Amnionless PF14828.6 GAX13382.1 - 0.0073 15.2 0.2 0.014 14.3 0.2 1.4 1 0 0 1 1 1 1 Amnionless RT_RNaseH_2 PF17919.1 GAX13383.1 - 4.3e-31 106.9 0.0 1.2e-30 105.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAX13383.1 - 8.1e-27 93.6 0.0 2.7e-26 91.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAX13383.1 - 6.3e-22 78.2 0.0 1.3e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX13383.1 - 2e-13 50.6 0.0 3.6e-12 46.5 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 GAX13383.1 - 6.9e-08 32.5 0.8 1.9e-07 31.1 0.8 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain MLVIN_C PF18697.1 GAX13383.1 - 0.034 14.2 0.1 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVP PF00077.20 GAX13383.1 - 0.077 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RNA_pol_Rpb1_R PF05001.13 GAX13383.1 - 0.2 12.1 7.2 0.48 10.9 7.2 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat gag_pre-integrs PF13976.6 GAX13383.1 - 0.7 9.8 3.0 1.1 9.2 0.8 2.5 2 0 0 2 2 2 0 GAG-pre-integrase domain Guanylate_cyc PF00211.20 GAX13385.1 - 5.8e-41 140.1 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX13385.1 - 6.3e-32 111.2 2.2 6.3e-32 111.2 2.2 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 GAX13385.1 - 0.0006 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 CHASE domain DUF3482 PF11981.8 GAX13385.1 - 0.12 11.7 0.2 0.47 9.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) Sigma70_r2 PF04542.14 GAX13386.1 - 5.2e-09 35.7 0.6 8.4e-08 31.9 0.3 2.6 2 1 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 GAX13386.1 - 0.00019 21.5 0.8 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 1 Sigma-70 region 3 ABATE PF07336.11 GAX13386.1 - 0.012 16.3 0.5 0.75 10.5 0.1 2.5 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Folate_rec PF03024.14 GAX13387.1 - 3.9e-38 131.0 10.4 2e-32 112.4 9.6 2.1 2 0 0 2 2 2 2 Folate receptor family NPC1_N PF16414.5 GAX13387.1 - 0.0023 17.5 3.3 0.0033 17.0 3.3 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus DUF3177 PF11375.8 GAX13387.1 - 0.23 11.2 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Peptidase_M43 PF05572.13 GAX13388.1 - 5.4e-14 52.4 0.0 5.4e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX13388.1 - 1.3e-05 25.5 0.3 2.3e-05 24.7 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX13388.1 - 0.00069 20.1 0.1 0.0013 19.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX13388.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Phlebovirus_G2 PF07245.11 GAX13389.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Folate_rec PF03024.14 GAX13390.1 - 6.5e-35 120.5 7.6 5.7e-29 101.2 7.0 2.1 2 0 0 2 2 2 2 Folate receptor family Peptidase_M43 PF05572.13 GAX13391.1 - 2.2e-14 53.6 0.0 4.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX13391.1 - 1.6e-06 28.6 0.4 4e-06 27.3 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX13391.1 - 0.00031 21.0 1.1 0.00044 20.5 0.8 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX13391.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ada3 PF10198.9 GAX13392.1 - 1.2 9.3 13.0 1.8 8.7 13.0 1.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 NBD_C PF17042.5 GAX13392.1 - 1.5 9.4 5.3 0.92 10.0 3.3 1.6 1 1 1 2 2 2 0 Nucleotide-binding C-terminal domain RR_TM4-6 PF06459.12 GAX13392.1 - 2.2 8.1 6.8 2.8 7.7 6.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 GAX13392.1 - 5.4 4.0 6.0 6.1 3.8 6.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 GAX13392.1 - 5.4 5.7 6.3 6.1 5.5 6.3 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GAX13392.1 - 7.4 4.7 9.3 9.4 4.4 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 GAX13393.1 - 2e-25 89.9 0.0 3.8e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAX13393.1 - 2e-11 43.7 19.1 2.9e-11 43.2 19.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GAX13393.1 - 3.7e-07 30.2 0.2 0.00029 20.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX13393.1 - 0.0012 18.3 0.2 0.078 12.4 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 GAX13393.1 - 0.0028 17.4 0.1 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 GAX13393.1 - 0.0042 17.0 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GAX13393.1 - 0.0048 17.4 0.0 0.008 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX13393.1 - 0.019 15.4 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAX13393.1 - 0.032 14.5 0.1 0.082 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX13393.1 - 0.053 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAX13393.1 - 0.11 12.1 0.3 0.26 10.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain Mpv17_PMP22 PF04117.12 GAX13394.1 - 5.2e-15 55.4 0.2 1.4e-14 54.0 0.2 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family Trypsin PF00089.26 GAX13395.1 - 4.2e-34 118.3 0.0 6.2e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin Multi_Drug_Res PF00893.19 GAX13396.1 - 5.9e-13 49.3 2.0 7.2e-13 49.0 2.0 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 GAX13396.1 - 0.0012 19.0 3.7 0.0014 18.8 3.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family DUF5381 PF17353.2 GAX13396.1 - 0.076 12.8 0.5 0.093 12.5 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Dickkopf_N PF04706.12 GAX13397.1 - 1.7 9.2 9.8 0.81 10.2 7.2 1.9 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Peptidase_S8 PF00082.22 GAX13398.1 - 6.8e-40 137.2 3.3 1.3e-39 136.3 3.3 1.4 1 1 0 1 1 1 1 Subtilase family DNA_pol3_beta PF00712.19 GAX13398.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain PT PF04886.12 GAX13399.1 - 0.0013 18.3 10.1 0.0013 18.3 10.1 4.1 1 1 1 2 2 2 1 PT repeat Dickkopf_N PF04706.12 GAX13399.1 - 0.005 17.3 6.0 0.0056 17.1 4.2 2.0 1 1 1 2 2 2 1 Dickkopf N-terminal cysteine-rich region DUF2486 PF10667.9 GAX13399.1 - 4.7 7.3 8.3 6 7.0 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Peptidase_S8 PF00082.22 GAX13400.1 - 6.6e-40 137.2 2.9 8.9e-40 136.8 2.9 1.2 1 0 0 1 1 1 1 Subtilase family FeS_assembly_P PF01883.19 GAX13401.1 - 9e-10 38.6 0.0 2.3e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein zf-RING_UBOX PF13445.6 GAX13402.1 - 6.8e-07 29.2 13.9 2.1e-06 27.6 13.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX13402.1 - 1.1e-05 25.7 17.9 4e-05 23.9 17.9 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAX13402.1 - 1.2e-05 25.0 13.8 3.3e-05 23.7 13.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX13402.1 - 1.8e-05 24.5 17.9 4.8e-05 23.1 17.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAX13402.1 - 0.0004 20.5 17.8 0.0013 18.8 17.8 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAX13402.1 - 0.0014 18.4 20.2 0.011 15.5 20.2 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX13402.1 - 0.041 13.8 17.4 0.11 12.4 17.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_trans_1_2 PF13524.6 GAX13403.1 - 0.00081 19.7 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX13403.1 - 0.015 14.8 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Sec6 PF06046.13 GAX13404.1 - 6.8e-20 71.0 1.6 2.7e-19 69.0 1.6 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec6 DUF3802 PF12290.8 GAX13404.1 - 0.0023 18.4 0.2 0.0092 16.5 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3802) FerA PF08165.11 GAX13404.1 - 0.1 12.6 0.9 3 7.9 0.1 3.0 2 0 0 2 2 2 0 FerA (NUC095) domain CRAL_TRIO PF00650.20 GAX13405.1 - 1e-23 83.8 0.0 1.6e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAX13405.1 - 0.0052 16.9 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RNA_pol_Rpb4 PF03874.16 GAX13406.1 - 8.4e-16 58.4 1.4 1.2e-15 57.9 1.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 CHGN PF05679.16 GAX13406.1 - 0.018 13.9 1.0 0.02 13.7 1.0 1.2 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase DUF4205 PF13898.6 GAX13407.1 - 7.9e-05 21.7 0.5 0.0019 17.2 0.5 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) UBA_4 PF14555.6 GAX13407.1 - 0.0021 17.8 0.1 0.0048 16.7 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain tRNA_bind PF01588.20 GAX13408.1 - 6.1e-10 39.1 1.1 1e-09 38.4 1.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain V-ATPase_H_C PF11698.8 GAX13409.1 - 2.4e-29 101.8 0.1 5.5e-29 100.7 0.1 1.7 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 GAX13409.1 - 4e-27 95.3 0.1 8.8e-27 94.2 0.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 GAX13409.1 - 4.9e-07 29.6 1.0 0.00047 20.1 0.1 3.2 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Cyt-b5 PF00173.28 GAX13409.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Adeno_E3_CR2 PF02439.15 GAX13410.1 - 0.00041 20.0 3.6 0.0007 19.3 3.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 PDZ_6 PF17820.1 GAX13410.1 - 0.00065 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX13410.1 - 0.0015 18.8 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX13410.1 - 0.014 15.7 0.1 0.033 14.5 0.1 1.7 1 0 0 1 1 1 0 PDZ domain Pilin_N PF07790.11 GAX13410.1 - 0.08 13.9 0.4 0.42 11.6 0.1 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF4813 PF16072.5 GAX13410.1 - 0.13 11.9 0.3 0.2 11.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Longin PF13774.6 GAX13411.1 - 8.1e-17 61.0 0.0 1.6e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAX13411.1 - 3e-16 59.0 0.3 7.1e-16 57.8 0.1 1.7 2 0 0 2 2 2 1 Synaptobrevin OmpH PF03938.14 GAX13411.1 - 2.2 8.6 6.8 0.38 11.1 2.1 2.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5600 PF18150.1 GAX13412.1 - 4e-32 111.0 0.2 8.9e-32 109.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 GAX13412.1 - 7.2e-15 55.4 0.0 3.2e-13 50.1 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 GAX13412.1 - 9.7e-14 51.0 0.1 1.8e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 GAX13412.1 - 1.6e-08 34.6 0.0 3.5e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 GAX13412.1 - 0.014 15.7 0.2 0.9 9.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 GAX13412.1 - 0.075 12.3 0.0 0.91 8.8 0.0 2.5 3 0 0 3 3 3 0 AIG1 family Gtr1_RagA PF04670.12 GAX13412.1 - 0.11 11.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAX13412.1 - 0.16 11.9 0.1 62 3.4 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 GAX13412.1 - 0.21 11.1 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.22 GAX13412.1 - 0.26 10.9 0.2 18 4.9 0.0 2.4 2 0 0 2 2 2 0 Ras family DUF5323 PF17257.2 GAX13413.1 - 5.8e-07 29.3 0.3 7.6e-07 28.9 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5323) S1 PF00575.23 GAX13414.1 - 3.1e-20 72.3 12.4 8.1e-14 51.7 0.6 3.0 2 1 0 2 2 2 2 S1 RNA binding domain DUF2110 PF09883.9 GAX13414.1 - 0.015 14.9 0.1 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) S1_2 PF13509.6 GAX13414.1 - 0.05 13.7 0.1 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 S1 domain EXOSC1 PF10447.9 GAX13414.1 - 0.83 10.3 6.0 16 6.1 0.3 3.4 3 1 1 4 4 4 0 Exosome component EXOSC1/CSL4 LZ_Tnp_IS66 PF13007.7 GAX13414.1 - 1.8 9.4 8.3 7.9 7.3 4.0 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain TPR_12 PF13424.6 GAX13415.1 - 7.7e-48 160.7 14.7 1.2e-11 44.7 0.0 9.4 5 2 5 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX13415.1 - 1.1e-27 93.9 8.1 0.015 15.3 0.0 13.9 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX13415.1 - 4.2e-22 77.0 6.1 0.0076 16.0 0.1 11.3 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX13415.1 - 1.3e-20 74.0 0.1 3.9e-05 23.2 0.3 5.3 1 1 4 5 5 5 5 MalT-like TPR region TPR_8 PF13181.6 GAX13415.1 - 2.1e-19 68.0 11.3 0.021 15.0 0.0 11.3 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX13415.1 - 1.1e-16 59.5 5.7 2 8.7 0.0 9.9 8 1 1 9 9 9 5 Tetratricopeptide repeat NB-ARC PF00931.22 GAX13415.1 - 6.1e-12 45.3 1.3 1.5e-11 44.0 1.3 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 GAX13415.1 - 9.9e-10 38.0 0.9 0.076 12.9 0.0 8.9 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX13415.1 - 1.1e-08 35.2 7.3 2.9 8.9 0.0 10.5 10 3 2 13 13 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX13415.1 - 2.7e-08 33.4 0.0 1.2 8.9 0.0 6.6 7 0 0 7 7 7 2 TPR repeat TPR_6 PF13174.6 GAX13415.1 - 5.1e-08 33.0 0.1 3 8.7 0.0 9.1 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX13415.1 - 5.6e-08 33.3 0.5 1.1 10.0 0.0 7.9 9 1 1 10 10 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX13415.1 - 4.8e-05 23.8 5.1 0.13 12.8 0.1 6.8 5 3 1 7 7 6 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX13415.1 - 0.0074 16.0 2.0 11 5.7 0.3 4.1 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 GAX13415.1 - 0.011 16.1 0.0 13 6.4 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX13415.1 - 0.025 15.2 0.0 14 6.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos_3 PF14582.6 GAX13415.1 - 0.037 13.4 0.8 0.08 12.3 0.8 1.5 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF627 PF04781.12 GAX13415.1 - 0.043 13.8 0.3 1.8 8.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_21 PF09976.9 GAX13415.1 - 0.06 13.0 1.2 15 5.2 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain DUF4848 PF16140.5 GAX13415.1 - 0.1 12.1 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) SPO22 PF08631.10 GAX13415.1 - 0.22 10.9 7.3 0.27 10.7 0.0 3.9 5 0 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like ANAPC5 PF12862.7 GAX13415.1 - 1.5 9.0 7.6 5.2 7.2 0.1 4.7 5 1 1 6 6 5 0 Anaphase-promoting complex subunit 5 zf-Tim10_DDP PF02953.15 GAX13416.1 - 2e-10 40.2 1.7 2e-10 40.2 1.7 3.0 2 1 0 2 2 2 1 Tim10/DDP family zinc finger NAD_binding_10 PF13460.6 GAX13417.1 - 7.1e-13 48.9 0.0 0.00049 20.0 0.0 4.0 3 1 0 3 3 3 2 NAD(P)H-binding NmrA PF05368.13 GAX13417.1 - 0.0017 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 GAX13417.1 - 0.0037 16.5 0.0 0.062 12.5 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein DapB_N PF01113.20 GAX13417.1 - 0.007 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 GAX13417.1 - 0.021 15.2 0.1 0.061 13.7 0.0 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Epimerase PF01370.21 GAX13417.1 - 0.023 14.2 0.1 0.046 13.2 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAX13417.1 - 0.023 14.9 0.0 0.16 12.2 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GHL6 PF14871.6 GAX13417.1 - 0.1 12.8 0.3 6.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 6 LCIB_C_CA PF18599.1 GAX13418.1 - 1e-68 231.0 0.0 1.2e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Aft1_HRA PF11786.8 GAX13418.1 - 0.07 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Aft1 HRA domain Phage_portal PF04860.12 GAX13418.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein Lung_7-TM_R PF06814.13 GAX13419.1 - 2.9e-28 99.0 24.1 2.5e-26 92.6 24.1 2.9 1 1 0 1 1 1 1 Lung seven transmembrane receptor VPS13_C PF16909.5 GAX13420.1 - 6.4e-44 149.9 0.1 2e-43 148.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 GAX13420.1 - 6.1e-34 117.9 0.0 1.9e-33 116.2 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 GAX13420.1 - 1.4e-12 47.8 0.0 3.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAX13420.1 - 6.4e-05 23.2 0.1 0.0018 18.6 0.1 2.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain FtsL PF04999.13 GAX13421.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.6 2 0 0 2 2 2 0 Cell division protein FtsL DUF2116 PF09889.9 GAX13421.1 - 0.62 10.1 2.8 0.65 10.0 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) POP1 PF06978.11 GAX13422.1 - 1.1e-06 28.8 2.4 1.1e-06 28.8 2.4 2.1 1 1 1 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 GAX13422.1 - 3.6e-05 24.0 0.0 0.00012 22.3 0.0 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.11 GAX13422.1 - 0.00054 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Taxilin PF09728.9 GAX13423.1 - 0.00012 21.4 10.7 0.00012 21.4 10.7 2.6 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF3450 PF11932.8 GAX13423.1 - 0.00096 18.5 5.8 0.00096 18.5 5.8 4.3 3 1 0 4 4 4 2 Protein of unknown function (DUF3450) Serine_rich PF08824.10 GAX13423.1 - 0.002 18.1 2.6 0.002 18.1 2.6 3.9 4 1 0 4 4 4 1 Serine rich protein interaction domain Fib_alpha PF08702.10 GAX13423.1 - 0.025 14.8 32.0 0.031 14.4 6.1 4.6 2 1 2 5 5 5 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 GAX13423.1 - 0.035 14.4 1.6 0.035 14.4 1.6 5.6 4 3 2 6 6 6 0 Uncharacterized conserved protein WXG100 PF06013.12 GAX13423.1 - 0.042 14.1 19.9 0.096 12.9 1.2 5.1 3 2 1 4 4 4 0 Proteins of 100 residues with WXG Occludin_ELL PF07303.13 GAX13423.1 - 8.1 7.2 26.5 1.6 9.5 4.3 4.9 3 1 2 5 5 5 0 Occludin homology domain HRDC PF00570.23 GAX13424.1 - 0.009 16.0 1.9 0.086 12.8 0.2 2.7 2 0 0 2 2 2 1 HRDC domain Glyco_hydro_114 PF03537.13 GAX13424.1 - 0.051 12.9 2.2 0.067 12.5 2.2 1.2 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 ATG16 PF08614.11 GAX13424.1 - 0.28 11.4 49.1 0.9 9.7 4.9 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TPK_catalytic PF04263.16 GAX13424.1 - 0.61 10.1 4.4 0.36 10.9 0.5 2.1 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DUF3644 PF12358.8 GAX13424.1 - 0.74 10.3 3.9 5.7 7.5 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3644) DASH_Dam1 PF08653.10 GAX13424.1 - 1.8 8.5 13.7 0.77 9.6 0.5 4.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 HisKA_2 PF07568.12 GAX13424.1 - 6 7.0 11.0 0.082 13.0 1.1 2.8 3 1 0 3 3 3 0 Histidine kinase ArAE_2_N PF10337.9 GAX13424.1 - 7.3 5.5 14.7 9.6 5.1 14.2 1.4 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal AAA PF00004.29 GAX13425.1 - 2.4e-36 125.1 0.0 5.4e-36 123.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX13425.1 - 7.6e-09 35.2 0.1 3.2e-08 33.2 0.1 2.2 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 GAX13425.1 - 3.7e-05 23.6 0.0 8.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 GAX13425.1 - 6.4e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX13425.1 - 0.00051 20.3 0.6 0.019 15.2 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX13425.1 - 0.00053 20.2 0.3 0.0035 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX13425.1 - 0.00098 19.1 0.1 0.0062 16.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX13425.1 - 0.0013 18.8 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAX13425.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAX13425.1 - 0.0047 16.3 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GAX13425.1 - 0.0054 17.1 9.6 0.059 13.8 0.6 5.4 4 1 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 GAX13425.1 - 0.0073 16.8 0.3 0.12 12.9 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 GAX13425.1 - 0.013 15.5 0.0 0.04 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX13425.1 - 0.018 14.8 0.1 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 GAX13425.1 - 0.019 14.2 0.2 0.047 12.9 0.1 1.7 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 GAX13425.1 - 0.056 13.7 0.6 0.55 10.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX13425.1 - 0.059 12.9 0.0 0.63 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 GAX13425.1 - 0.13 12.5 3.1 2.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Armet PF10208.9 GAX13426.1 - 5.2e-30 104.3 10.0 8.1e-30 103.7 10.0 1.2 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 GAX13426.1 - 0.00077 19.2 0.1 0.0016 18.1 0.1 1.6 1 0 0 1 1 1 1 SAP domain Uteroglobin PF01099.17 GAX13426.1 - 0.013 15.8 0.7 0.032 14.6 0.7 1.7 1 0 0 1 1 1 0 Uteroglobin family HeH PF12949.7 GAX13426.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain DHR10 PF18595.1 GAX13426.1 - 0.77 9.8 5.3 2.3 8.3 0.2 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TPR_12 PF13424.6 GAX13427.1 - 1.3e-85 281.7 26.8 1.2e-15 57.6 0.0 9.7 5 3 5 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.28 GAX13427.1 - 1.5e-55 182.9 10.7 3.2e-05 23.5 0.0 14.8 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_10 PF13374.6 GAX13427.1 - 4.9e-52 172.5 20.1 6.2e-06 25.9 0.2 13.7 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_2 PF07719.17 GAX13427.1 - 3.7e-44 145.3 22.3 0.00078 19.4 0.0 15.2 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAX13427.1 - 5.4e-36 119.8 23.1 0.0043 17.2 0.0 14.0 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_7 PF13176.6 GAX13427.1 - 1.9e-33 112.0 16.2 7.7e-05 22.5 0.1 13.6 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_11 PF13414.6 GAX13427.1 - 7.1e-20 70.4 9.5 0.017 14.8 0.0 10.3 10 1 0 10 10 9 4 TPR repeat NB-ARC PF00931.22 GAX13427.1 - 3.3e-16 59.3 0.0 6.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 GAX13427.1 - 3.5e-16 59.5 12.1 0.006 16.0 0.2 5.7 1 1 5 6 6 6 6 MalT-like TPR region TPR_14 PF13428.6 GAX13427.1 - 3.4e-12 46.1 11.5 14 6.9 0.0 12.3 9 3 3 12 12 12 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX13427.1 - 1.9e-09 37.5 13.2 14 6.6 0.0 11.4 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX13427.1 - 2e-07 31.5 0.4 0.014 16.0 0.0 7.3 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX13427.1 - 9e-07 28.9 2.6 17 6.0 0.0 8.5 10 0 0 10 10 10 0 Tetratricopeptide repeat AAA_16 PF13191.6 GAX13427.1 - 3.2e-05 24.4 0.0 0.00012 22.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ANAPC3 PF12895.7 GAX13427.1 - 0.002 18.3 7.8 5.3 7.4 0.0 6.2 6 0 0 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAX13427.1 - 0.0077 16.7 13.2 24 5.6 0.0 7.9 7 1 2 9 9 9 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX13427.1 - 0.015 14.7 4.3 25 4.4 0.0 5.6 7 0 0 7 7 7 0 SHNi-TPR DUF627 PF04781.12 GAX13427.1 - 0.035 14.1 6.6 11 6.0 0.0 5.9 6 1 0 6 6 5 0 Protein of unknown function (DUF627) TPR_5 PF12688.7 GAX13427.1 - 0.068 13.4 1.4 9.5 6.5 0.0 4.7 5 1 0 5 5 4 0 Tetratrico peptide repeat DUF5113 PF17140.4 GAX13427.1 - 0.073 12.9 0.3 43 3.9 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF5113) ANAPC5 PF12862.7 GAX13427.1 - 0.091 12.8 15.1 9.3 6.4 0.2 7.4 4 3 2 6 6 6 0 Anaphase-promoting complex subunit 5 Actin PF00022.19 GAX13428.1 - 3.5e-45 154.3 0.0 1.4e-43 149.1 0.0 2.4 1 1 0 1 1 1 1 Actin YL1 PF05764.13 GAX13428.1 - 4.1e-06 27.1 21.6 4.1e-06 27.1 21.6 1.8 2 0 0 2 2 2 1 YL1 nuclear protein SDA1 PF05285.12 GAX13428.1 - 0.0045 16.5 30.1 0.0082 15.6 30.1 1.3 1 0 0 1 1 1 1 SDA1 SURF2 PF05477.11 GAX13428.1 - 0.034 13.8 8.6 0.055 13.2 8.6 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) MreB_Mbl PF06723.13 GAX13428.1 - 0.12 11.2 0.0 0.36 9.6 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Rgp1 PF08737.10 GAX13428.1 - 0.82 8.8 5.1 1.3 8.1 5.1 1.2 1 0 0 1 1 1 0 Rgp1 THOC2_N PF16134.5 GAX13428.1 - 1.4 7.4 8.4 2.7 6.5 8.4 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Vfa1 PF08432.10 GAX13428.1 - 1.4 9.2 11.6 3 8.2 11.6 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 GAX13428.1 - 1.6 7.0 24.3 2.7 6.2 24.3 1.3 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GAX13428.1 - 2.1 7.0 10.9 3 6.5 10.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 GAX13428.1 - 2.9 7.2 18.3 5.6 6.3 18.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 GAX13428.1 - 4 6.1 7.7 6.2 5.5 7.7 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GAX13428.1 - 6.5 4.8 37.3 9.3 4.3 37.3 1.1 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.13 GAX13428.1 - 8.5 4.8 24.6 13 4.2 24.6 1.2 1 0 0 1 1 1 0 Utp14 protein 2OG-FeII_Oxy_3 PF13640.6 GAX13429.1 - 6.1e-14 52.7 0.0 1.3e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Helicase_C_2 PF13307.6 GAX13430.1 - 9.6e-49 165.8 0.0 2.5e-48 164.5 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAX13430.1 - 1.7e-38 132.0 0.0 9.3e-38 129.6 0.0 2.3 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 GAX13430.1 - 0.0032 17.5 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 GAX13430.1 - 0.018 14.5 0.0 0.83 9.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 GAX13430.1 - 0.02 15.2 0.0 3 8.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain MID_MedPIWI PF18296.1 GAX13430.1 - 0.13 12.0 2.8 0.59 9.9 0.7 2.4 2 0 0 2 2 2 0 MID domain of medPIWI 2OG-FeII_Oxy_3 PF13640.6 GAX13431.1 - 1e-15 58.4 0.1 2.6e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UspB PF10625.9 GAX13431.1 - 0.056 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Universal stress protein B (UspB) VHL PF01847.16 GAX13431.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 VHL beta domain AAA_16 PF13191.6 GAX13432.1 - 1.3e-05 25.6 0.0 0.023 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 GAX13432.1 - 0.058 13.8 0.0 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 GAX13432.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Torsin PduV-EutP PF10662.9 GAX13432.1 - 0.11 12.3 0.0 4.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Aminotran_1_2 PF00155.21 GAX13433.1 - 2.1e-49 168.6 0.0 2.4e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX13433.1 - 1.5e-06 27.0 0.1 2.8e-06 26.1 0.1 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAX13433.1 - 0.00016 21.1 0.0 0.00037 19.9 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAX13433.1 - 0.0099 14.9 0.0 0.022 13.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAX13433.1 - 0.068 12.4 0.0 0.46 9.7 0.0 2.0 1 1 1 2 2 2 0 Beta-eliminating lyase Pkinase PF00069.25 GAX13436.1 - 1.3e-23 83.7 0.0 1.5e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13436.1 - 1.3e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX13436.1 - 1.1e-06 27.8 0.0 1.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX13436.1 - 4e-05 23.7 0.1 0.0034 17.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX13436.1 - 0.095 12.3 0.0 9 5.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 GAX13436.1 - 0.17 11.2 0.2 0.3 10.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2b PF00587.25 GAX13437.1 - 2.4e-21 76.5 0.0 4.2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 GAX13437.1 - 5e-20 71.5 0.3 5e-20 71.5 0.3 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 GAX13437.1 - 1.3e-12 47.7 0.3 3.1e-12 46.5 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 GAX13437.1 - 5.3e-10 39.3 1.8 5.3e-10 39.3 1.8 2.2 2 0 0 2 2 2 1 WHEP-TRS domain Rgp1 PF08737.10 GAX13437.1 - 0.15 11.2 1.6 0.25 10.5 1.6 1.2 1 0 0 1 1 1 0 Rgp1 Ribosomal_L19 PF01245.20 GAX13439.1 - 1.6e-18 66.7 0.6 2.5e-18 66.0 0.6 1.3 1 1 0 1 1 1 1 Ribosomal protein L19 NFACT-R_2 PF18297.1 GAX13439.1 - 0.0029 17.8 0.1 0.0042 17.3 0.1 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain DapB_C PF05173.14 GAX13439.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Acyltransferase PF01553.21 GAX13440.1 - 2.2e-25 88.9 0.0 4.1e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase PDZ_6 PF17820.1 GAX13441.1 - 5.2e-08 32.6 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX13441.1 - 6.1e-06 26.5 0.1 2.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX13441.1 - 0.0036 17.6 0.0 0.013 15.9 0.0 2.0 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 GAX13441.1 - 0.0085 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain PikAIV_N PF18605.1 GAX13441.1 - 0.23 11.1 10.5 0.035 13.7 0.7 4.5 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PDZ_4 PF17816.1 GAX13441.1 - 0.92 9.9 4.1 1.9 8.9 0.0 3.9 4 0 0 4 4 4 0 PDZ domain NAD_binding_4 PF07993.12 GAX13442.1 - 3.7e-42 144.3 0.0 5.9e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein FAD_binding_4 PF01565.23 GAX13442.1 - 2.4e-34 118.0 0.0 6.2e-34 116.7 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GAX13442.1 - 1.4e-33 116.6 0.0 3.1e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DegT_DnrJ_EryC1 PF01041.17 GAX13442.1 - 2e-20 73.4 0.0 3.9e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family ACBP PF00887.19 GAX13442.1 - 5.4e-19 68.2 0.0 1.3e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein Acyltransferase PF01553.21 GAX13442.1 - 4.1e-18 65.3 0.0 1e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase Epimerase PF01370.21 GAX13442.1 - 5.3e-07 29.4 0.0 2.1e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX13442.1 - 2.4e-06 27.2 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAX13442.1 - 0.013 14.6 0.2 0.057 12.5 0.2 2.2 1 1 0 1 1 1 0 RmlD substrate binding domain RGM_C PF06534.13 GAX13444.1 - 0.00022 20.8 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RelA_SpoT PF04607.17 GAX13444.1 - 0.17 12.2 0.0 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins FHA PF00498.26 GAX13445.1 - 0.00039 20.7 0.8 0.0048 17.2 0.1 2.7 2 1 0 2 2 2 1 FHA domain DUF2891 PF11199.8 GAX13445.1 - 0.057 12.3 0.1 0.089 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Abhydrolase_3 PF07859.13 GAX13446.1 - 1.3e-21 77.4 0.1 1.7e-21 77.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Eno-Rase_NADH_b PF12242.8 GAX13446.1 - 0.0021 17.8 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Acetyltransf_1 PF00583.25 GAX13447.1 - 1.7e-11 44.4 0.0 4e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family LCM PF04072.14 GAX13447.1 - 2.4e-10 40.7 0.0 5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_7 PF13508.7 GAX13447.1 - 3.6e-09 36.9 0.0 8.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX13447.1 - 2.8e-08 33.8 0.0 8.1e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAX13447.1 - 0.00082 19.1 0.0 0.0028 17.4 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 GAX13447.1 - 0.024 14.6 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 GAX13447.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PAPS_reduct PF01507.19 GAX13448.1 - 1.1e-13 51.6 0.0 3.2e-09 37.1 0.0 2.6 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 GAX13448.1 - 2.5e-09 37.0 0.1 6.1e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 GAX13448.1 - 0.0025 17.7 0.4 0.0046 16.9 0.4 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAX13448.1 - 0.0033 17.8 0.0 0.012 16.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX13448.1 - 0.11 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 GAX13448.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like ABC_membrane PF00664.23 GAX13449.1 - 1.5e-62 211.7 29.7 7.9e-33 114.3 7.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX13449.1 - 5.4e-46 156.5 0.0 1.2e-26 93.9 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAX13449.1 - 2.9e-11 43.3 2.8 0.00015 21.3 0.1 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 GAX13449.1 - 1.4e-05 25.3 0.4 0.012 15.7 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 GAX13449.1 - 1.4e-05 25.1 1.2 0.3 11.2 0.0 3.8 4 0 0 4 4 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX13449.1 - 0.00074 19.2 1.8 0.54 10.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 GAX13449.1 - 0.0022 18.1 8.0 0.0082 16.2 0.3 3.4 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.18 GAX13449.1 - 0.0027 17.1 0.5 1 8.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.6 GAX13449.1 - 0.0031 17.4 1.0 3.5 7.3 0.0 3.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX13449.1 - 0.0032 17.9 0.1 2.2 8.7 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX13449.1 - 0.004 17.4 0.6 6.6 7.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAX13449.1 - 0.0064 15.6 0.2 1.9 7.5 0.1 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 GAX13449.1 - 0.014 15.3 0.5 3.5 7.5 0.1 2.7 2 0 0 2 2 2 0 RsgA GTPase DEAD PF00270.29 GAX13449.1 - 0.015 15.1 1.3 0.14 12.0 0.2 3.0 3 1 0 3 3 3 0 DEAD/DEAH box helicase DUF3874 PF12990.7 GAX13449.1 - 0.034 14.5 0.3 0.098 13.0 0.3 1.8 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) AAA_7 PF12775.7 GAX13449.1 - 0.035 13.6 0.1 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 GAX13449.1 - 0.039 12.9 1.1 8.9 5.1 0.0 2.9 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 GAX13449.1 - 0.041 14.3 0.3 10 6.6 0.0 3.0 3 0 0 3 3 3 0 RNA helicase cobW PF02492.19 GAX13449.1 - 0.05 13.2 2.7 11 5.6 0.1 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 GAX13449.1 - 0.068 12.9 0.3 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IIGP PF05049.13 GAX13449.1 - 0.074 12.1 0.9 6.4 5.7 0.1 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.12 GAX13449.1 - 0.13 12.2 0.5 9.3 6.1 0.0 3.1 3 0 0 3 3 3 0 NACHT domain PARM PF17061.5 GAX13449.1 - 0.18 11.9 1.7 0.35 11.0 1.7 1.4 1 0 0 1 1 1 0 PARM Multi_Drug_Res PF00893.19 GAX13449.1 - 0.59 10.8 4.9 3.3 8.4 0.8 3.1 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF3987 PF13148.6 GAX13449.1 - 9.6 5.1 6.4 44 2.9 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Glyco_transf_34 PF05637.12 GAX13450.1 - 4.7e-19 69.1 3.4 2.2e-10 40.7 1.6 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GAX13450.1 - 6.9e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 GAX13450.1 - 9.8e-05 22.4 0.7 0.00016 21.7 0.7 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_tranf_2_3 PF13641.6 GAX13450.1 - 0.1 12.5 0.1 0.59 10.0 0.0 2.0 1 1 0 2 2 2 0 Glycosyltransferase like family 2 TLD PF07534.16 GAX13451.1 - 3.1e-22 79.3 0.0 8e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 TLD SNAPc_SNAP43 PF09808.9 GAX13452.1 - 0.0013 18.7 0.4 0.019 14.9 0.1 2.5 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 BSP_II PF05432.11 GAX13452.1 - 0.24 11.1 3.1 0.38 10.4 3.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TatD_DNase PF01026.21 GAX13454.1 - 5.7e-41 140.6 0.0 6.6e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase WD40 PF00400.32 GAX13456.1 - 2.1e-06 28.3 26.3 0.095 13.6 1.7 10.0 10 2 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX13456.1 - 5.8e-05 23.3 3.4 4.4 7.7 0.0 5.8 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain HECT PF00632.25 GAX13457.1 - 3.5e-86 289.5 0.0 4.5e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Mito_carr PF00153.27 GAX13458.1 - 3.2e-52 174.4 7.4 4.9e-22 77.7 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 GAX13458.1 - 0.0043 16.3 0.1 0.037 13.2 0.1 2.2 2 1 0 2 2 2 1 Gammaproteobacterial serine protease HTH_3 PF01381.22 GAX13459.1 - 1e-13 51.1 0.4 1.8e-13 50.3 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 GAX13459.1 - 2.7e-08 34.2 0.6 1.3e-07 31.9 0.1 2.3 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 GAX13459.1 - 0.0047 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 GAX13459.1 - 0.0092 16.0 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TRAP-gamma PF07074.12 GAX13459.1 - 0.33 10.5 0.9 0.48 10.0 0.4 1.4 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Proteasome PF00227.26 GAX13460.1 - 1e-10 41.4 0.0 3.6e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX13460.1 - 3.3e-07 29.8 0.1 5.7e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AAA PF00004.29 GAX13461.1 - 3.2e-82 273.5 0.0 2e-45 154.5 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX13461.1 - 3e-19 68.5 0.5 1.2e-09 37.9 0.0 3.0 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAX13461.1 - 1e-11 45.5 1.2 0.0033 17.8 0.0 4.8 3 2 0 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 GAX13461.1 - 1.7e-08 34.4 0.1 5.9e-05 22.9 0.0 3.7 3 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX13461.1 - 9.8e-08 32.1 0.6 0.0052 16.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Nucleolin_bd PF16725.5 GAX13461.1 - 2.2e-07 30.4 0.3 5.3e-07 29.2 0.3 1.6 1 0 0 1 1 1 1 Nucleolin binding domain AAA_22 PF13401.6 GAX13461.1 - 2.2e-07 31.2 0.0 0.019 15.2 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 GAX13461.1 - 2.6e-07 30.9 2.5 0.022 14.9 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA_2 PF07724.14 GAX13461.1 - 3.3e-06 27.3 0.0 0.0049 17.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAX13461.1 - 5e-06 26.4 0.1 0.016 15.0 0.1 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAX13461.1 - 5.4e-06 25.9 0.2 0.03 13.7 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAX13461.1 - 1.4e-05 25.4 0.0 0.022 15.1 0.0 2.8 3 0 0 3 3 2 1 RNA helicase TIP49 PF06068.13 GAX13461.1 - 3.8e-05 23.1 0.1 0.054 12.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 GAX13461.1 - 7.3e-05 23.3 4.9 0.052 14.1 0.0 4.2 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 GAX13461.1 - 0.00013 22.5 2.7 0.099 13.2 0.0 3.6 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.12 GAX13461.1 - 0.00047 20.1 0.2 0.21 11.5 0.0 2.7 2 1 0 2 2 2 1 NACHT domain ATPase PF06745.13 GAX13461.1 - 0.00062 19.2 0.9 1.2 8.4 0.0 3.1 3 0 0 3 3 3 2 KaiC AAA_28 PF13521.6 GAX13461.1 - 0.00097 19.4 0.2 0.12 12.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 GAX13461.1 - 0.0011 18.8 0.0 0.46 10.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAX13461.1 - 0.0016 17.7 0.3 0.18 11.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 GAX13461.1 - 0.0017 18.4 0.0 0.03 14.3 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 GAX13461.1 - 0.0018 17.4 0.1 0.1 11.6 0.1 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 GAX13461.1 - 0.0021 18.1 0.0 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX13461.1 - 0.0034 17.0 0.1 0.53 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAX13461.1 - 0.0038 16.7 0.0 3.9 6.9 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 GAX13461.1 - 0.0058 16.4 0.4 0.3 10.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAX13461.1 - 0.0076 15.4 0.0 2.1 7.4 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 GAX13461.1 - 0.0089 16.0 0.0 0.099 12.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 GAX13461.1 - 0.022 14.5 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 GAX13461.1 - 0.025 14.5 0.0 0.39 10.6 0.0 2.9 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GAX13461.1 - 0.035 13.3 0.0 0.46 9.6 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain Sigma54_activ_2 PF14532.6 GAX13461.1 - 0.082 13.0 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 GAX13461.1 - 0.094 12.2 0.6 4.4 6.7 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 GAX13461.1 - 0.11 12.3 8.3 10 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 GAX13461.1 - 0.15 11.7 0.1 14 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAX13461.1 - 0.48 10.9 0.0 0.48 10.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain His_Phos_1 PF00300.22 GAX13462.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ArfGap PF01412.18 GAX13463.1 - 6.2e-32 110.1 0.0 6.2e-32 110.1 0.0 3.2 2 2 0 2 2 2 1 Putative GTPase activating protein for Arf Kinesin PF00225.23 GAX13463.1 - 0.0092 14.9 0.0 0.0092 14.9 0.0 1.9 1 1 1 2 2 2 1 Kinesin motor domain DnaJ_C PF01556.18 GAX13464.1 - 8.4e-39 133.0 0.5 1.3e-38 132.4 0.5 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX13464.1 - 1.5e-24 85.8 1.7 2.5e-24 85.2 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAX13464.1 - 3e-07 30.7 5.0 5.8e-07 29.8 5.0 1.4 1 0 0 1 1 1 1 DnaJ central domain PP2C PF00481.21 GAX13465.1 - 4.2e-46 157.7 0.5 8.9e-46 156.6 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX13465.1 - 9e-07 29.0 0.0 4.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAX13465.1 - 6e-06 26.0 0.5 0.0084 15.8 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C WD40 PF00400.32 GAX13467.1 - 3e-10 40.5 3.3 0.0082 17.0 0.4 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Urotensin_II PF02083.15 GAX13469.1 - 0.32 10.8 2.2 0.86 9.4 0.2 2.4 2 0 0 2 2 2 0 Urotensin II Aldo_ket_red PF00248.21 GAX13470.1 - 2.5e-16 59.8 0.0 4.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family PseudoU_synth_1 PF01416.20 GAX13471.1 - 0.0017 18.8 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridine synthase zf-C2H2 PF00096.26 GAX13471.1 - 0.018 15.5 0.2 0.039 14.4 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAX13471.1 - 0.17 12.8 0.2 0.51 11.3 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger QueT PF06177.11 GAX13472.1 - 1.9 8.8 13.4 0.045 14.1 3.6 2.5 1 1 1 2 2 2 0 QueT transporter RsbU_N PF08673.10 GAX13474.1 - 1.3 9.1 2.9 9.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain SAP PF02037.27 GAX13475.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 SAP domain MCM_bind PF09739.9 GAX13476.1 - 1.5e-38 132.6 0.1 3.5e-33 114.9 0.0 3.1 2 1 1 3 3 3 3 Mini-chromosome maintenance replisome factor HEPPP_synt_1 PF07307.11 GAX13477.1 - 0.0061 16.2 3.5 0.11 12.1 0.3 2.5 2 0 0 2 2 2 2 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 RasGAP_C PF03836.15 GAX13477.1 - 0.067 13.3 0.6 0.21 11.8 0.6 1.8 1 0 0 1 1 1 0 RasGAP C-terminus YbaB_DNA_bd PF02575.16 GAX13477.1 - 0.54 10.5 6.4 1.1 9.5 0.0 3.8 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family WXG100 PF06013.12 GAX13477.1 - 0.61 10.4 4.0 1.4 9.2 0.3 3.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Cpn60_TCP1 PF00118.24 GAX13478.1 - 1.2e-159 532.1 4.3 1.4e-159 531.9 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1279 PF06916.13 GAX13479.1 - 3.2e-21 75.7 0.1 7.1e-21 74.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) IspD PF01128.19 GAX13480.1 - 9.3e-47 159.6 0.0 1.6e-46 158.8 0.0 1.3 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 GAX13480.1 - 1.1e-07 32.3 0.1 6.3e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 MobA-like NTP transferase domain Pro_isomerase PF00160.21 GAX13484.1 - 0.0057 16.9 0.0 0.022 15.0 0.0 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GIT_CC PF16559.5 GAX13484.1 - 0.85 9.5 5.6 1.1 9.2 4.1 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Pkinase PF00069.25 GAX13485.1 - 3.6e-57 193.7 0.0 6e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX13485.1 - 2.9e-51 171.5 0.1 4.4e-19 68.4 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX13485.1 - 2.2e-29 102.5 0.0 3.7e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX13485.1 - 0.062 12.2 0.2 0.19 10.6 0.2 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 GAX13485.1 - 0.084 12.2 0.0 2.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like DUF3783 PF12646.7 GAX13485.1 - 2 8.4 3.6 51 3.9 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3783) Carn_acyltransf PF00755.20 GAX13486.1 - 1.1e-179 598.9 0.0 1.3e-179 598.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pro_isomerase PF00160.21 GAX13487.1 - 1.6e-09 38.2 0.0 2.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2048 PF09752.9 GAX13487.1 - 0.013 14.7 0.8 0.019 14.1 0.8 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Prismane PF03063.20 GAX13487.1 - 0.03 13.0 0.3 0.043 12.5 0.3 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family INT_SG_DDX_CT_C PF15300.6 GAX13487.1 - 0.093 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Pyr_redox_2 PF07992.14 GAX13488.1 - 2.9e-41 141.6 1.8 9.4e-41 140.0 1.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX13488.1 - 3.7e-24 85.5 3.6 1.6e-19 70.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 GAX13488.1 - 1.1e-19 70.3 0.0 2.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.27 GAX13488.1 - 1.3e-16 60.9 0.9 1.5e-13 51.1 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX13488.1 - 6.6e-06 25.1 5.3 0.018 13.7 0.5 3.6 3 0 0 3 3 3 3 HI0933-like protein Thioredoxin_2 PF13098.6 GAX13488.1 - 7e-06 26.5 0.1 3.3e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain NAD_binding_7 PF13241.6 GAX13488.1 - 1e-05 25.9 0.7 0.0057 17.1 0.1 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 GAX13488.1 - 1.4e-05 24.3 13.6 0.0038 16.4 2.8 4.2 3 1 1 4 4 4 2 FAD binding domain Thi4 PF01946.17 GAX13488.1 - 0.00026 20.3 0.7 0.033 13.4 0.4 2.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 GAX13488.1 - 0.00039 19.9 1.6 0.00039 19.9 1.6 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAX13488.1 - 0.00043 19.5 0.2 0.032 13.4 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 GAX13488.1 - 0.0006 19.2 3.3 0.024 13.9 0.8 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAX13488.1 - 0.00061 20.0 2.7 0.023 14.9 0.6 3.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SR-25 PF10500.9 GAX13488.1 - 0.00076 19.2 8.6 0.0013 18.4 8.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Thioredoxin_7 PF13899.6 GAX13488.1 - 0.003 17.7 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like DAO PF01266.24 GAX13488.1 - 0.0043 16.7 16.9 0.095 12.3 2.8 4.5 4 1 0 5 5 5 1 FAD dependent oxidoreductase IMUP PF15761.5 GAX13488.1 - 0.0052 17.5 6.7 0.014 16.1 6.7 1.8 1 0 0 1 1 1 1 Immortalisation up-regulated protein TraF PF13728.6 GAX13488.1 - 0.0053 16.6 3.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein GIDA PF01134.22 GAX13488.1 - 0.007 15.5 2.5 0.007 15.5 2.5 4.1 4 1 1 5 5 5 2 Glucose inhibited division protein A OST3_OST6 PF04756.13 GAX13488.1 - 0.014 14.8 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AlaDh_PNT_C PF01262.21 GAX13488.1 - 0.021 14.1 3.3 0.55 9.5 0.1 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain MID_MedPIWI PF18296.1 GAX13488.1 - 0.03 14.1 2.2 0.048 13.4 2.2 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Trp_halogenase PF04820.14 GAX13488.1 - 0.041 12.7 1.7 1.1 8.0 0.4 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Dehydrin PF00257.19 GAX13488.1 - 0.048 14.2 7.0 0.26 11.9 3.1 2.6 2 0 0 2 2 2 0 Dehydrin Gon7 PF08738.10 GAX13488.1 - 0.1 12.7 1.4 0.24 11.5 1.1 1.7 2 0 0 2 2 1 0 Gon7 family eIF-3c_N PF05470.12 GAX13488.1 - 0.59 8.4 2.6 0.87 7.8 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Lycopene_cycl PF05834.12 GAX13488.1 - 1.2 8.1 6.8 0.48 9.4 1.4 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAX13488.1 - 2.1 8.3 4.6 45 4.0 0.4 3.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding RAP1 PF07218.11 GAX13488.1 - 2.4 6.3 7.6 3.5 5.8 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_pp85 PF04637.12 GAX13488.1 - 2.6 6.4 4.5 3.8 5.8 4.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Jnk-SapK_ap_N PF09744.9 GAX13488.1 - 2.6 8.2 6.9 21 5.3 6.4 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 RPA_interact_M PF14767.6 GAX13488.1 - 6.4 7.4 7.8 6.5 7.4 4.9 2.2 2 0 0 2 2 2 0 Replication protein A interacting middle Chorion_2 PF03964.15 GAX13488.1 - 7.2 7.5 9.2 2.3 9.1 2.3 2.4 2 0 0 2 2 2 0 Chorion family 2 PT PF04886.12 GAX13489.1 - 7.6e-06 25.4 98.5 0.00071 19.1 5.5 7.7 4 2 0 4 4 4 3 PT repeat Aha1_N PF09229.11 GAX13490.1 - 1.4e-14 54.4 0.3 4.1e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.17 GAX13490.1 - 3.3e-08 33.0 0.0 0.015 15.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX13490.1 - 1.5e-07 31.0 0.1 0.036 13.7 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.28 GAX13490.1 - 5.6e-07 29.1 0.0 0.041 13.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX13490.1 - 9.4e-05 23.0 0.2 0.0089 16.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX13490.1 - 0.0016 18.5 0.2 0.0055 16.8 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX13490.1 - 0.0026 18.4 0.7 0.075 13.9 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX13490.1 - 0.0028 17.6 0.0 4.7 7.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX13490.1 - 0.0045 17.5 2.6 0.054 14.0 0.0 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX13490.1 - 0.0058 16.9 0.1 0.22 11.8 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX13490.1 - 0.0079 16.3 0.0 0.21 11.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX13490.1 - 0.016 15.1 0.5 9.2 6.3 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 GAX13491.1 - 0.0037 17.2 0.0 1.9 8.7 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeat Env-gp36 PF09590.10 GAX13491.1 - 0.032 12.7 0.0 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein LRR_1 PF00560.33 GAX13491.1 - 0.079 13.6 0.1 25 5.9 0.0 3.2 3 1 0 3 3 3 0 Leucine Rich Repeat TA_inhibitor PF17574.2 GAX13491.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) LRR_2 PF07723.13 GAX13491.1 - 0.61 10.8 2.6 2.7 8.8 0.2 3.2 3 1 0 3 3 3 0 Leucine Rich Repeat LtrA PF06772.11 GAX13492.1 - 7.6e-18 64.8 22.2 7.6e-18 64.8 22.2 1.7 1 1 1 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) PIG-F PF06699.11 GAX13492.1 - 0.0019 18.4 1.5 0.0048 17.1 1.5 1.7 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F YlaC PF10777.9 GAX13492.1 - 4 7.3 4.8 2 8.2 0.2 2.5 3 0 0 3 3 3 0 Inner membrane protein YlaC DHHC PF01529.20 GAX13493.1 - 2.1e-20 73.2 7.9 2.1e-20 73.2 7.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase UNC119_bdg PF15435.6 GAX13493.1 - 0.67 9.5 1.7 1.1 8.8 1.7 1.2 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue DUF325 PF03804.13 GAX13494.1 - 0.0086 16.1 0.1 8.7 6.5 0.0 2.7 2 0 0 2 2 2 2 Viral proteins of unknown function BON PF04972.17 GAX13494.1 - 0.028 14.7 0.3 13 6.1 0.0 2.6 3 0 0 3 3 3 0 BON domain DUF2093 PF09866.9 GAX13494.1 - 0.13 11.7 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) TB PF00683.17 GAX13494.1 - 1.2 9.0 3.1 27 4.6 0.2 2.4 2 0 0 2 2 2 0 TB domain WD40 PF00400.32 GAX13495.1 - 0.0043 17.9 1.4 0.07 14.0 0.1 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Dynamitin PF04912.14 GAX13496.1 - 8.8e-26 91.1 27.7 3.3e-23 82.7 27.7 2.4 1 1 0 1 1 1 1 Dynamitin Stathmin PF00836.19 GAX13496.1 - 0.0033 17.4 2.7 0.0033 17.4 2.7 2.8 3 0 0 3 3 3 1 Stathmin family Homeodomain PF00046.29 GAX13496.1 - 0.04 13.8 0.8 0.19 11.6 0.8 2.2 1 0 0 1 1 1 0 Homeodomain NPV_P10 PF05531.12 GAX13496.1 - 0.16 12.4 14.3 0.61 10.6 0.7 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 GAX13496.1 - 2.8 8.2 13.4 0.37 11.0 1.5 3.9 4 1 1 5 5 5 0 Haemolysin XhlA OmpH PF03938.14 GAX13496.1 - 7 7.0 25.1 5.9 7.2 3.7 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Allexi_40kDa PF05549.11 GAX13496.1 - 7.9 5.9 14.0 2.8 7.4 2.7 2.7 1 1 2 3 3 3 0 Allexivirus 40kDa protein Fringe PF02434.16 GAX13497.1 - 0.042 13.3 0.1 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 Fringe-like AIRS_C PF02769.22 GAX13498.1 - 4.7e-21 75.6 0.0 7.9e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 GAX13498.1 - 2.9e-11 43.9 0.1 7.4e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain SART-1 PF03343.13 GAX13499.1 - 1.4e-60 205.6 49.1 6e-54 183.7 46.7 2.8 2 1 0 2 2 2 2 SART-1 family RNA_polI_A14 PF08203.11 GAX13499.1 - 0.0021 18.7 1.9 0.023 15.4 1.9 2.9 1 0 0 1 1 1 1 Yeast RNA polymerase I subunit RPA14 Pyr_redox_2 PF07992.14 GAX13500.1 - 4.3e-56 190.3 0.0 5.3e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX13500.1 - 4.3e-27 94.6 0.0 7.7e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX13500.1 - 1.6e-16 60.6 2.3 5.1e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX13500.1 - 6.6e-09 35.4 0.1 6.7e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX13500.1 - 8.3e-06 25.1 5.3 0.00014 21.1 4.6 2.6 2 1 0 3 3 3 1 FAD binding domain GIDA PF01134.22 GAX13500.1 - 1.2e-05 24.6 0.0 2.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAX13500.1 - 0.00029 20.3 1.2 0.00044 19.7 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAX13500.1 - 0.00038 19.8 0.3 0.0012 18.2 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAX13500.1 - 0.0018 17.1 3.2 0.012 14.4 1.0 3.0 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.17 GAX13500.1 - 0.018 14.3 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 GAX13500.1 - 0.095 12.3 0.5 0.19 11.3 0.5 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX13500.1 - 0.13 12.2 0.8 7 6.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAX13500.1 - 0.4 9.7 0.9 0.84 8.6 0.9 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAX13500.1 - 1 9.7 5.6 0.13 12.5 0.6 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_18 PF12847.7 GAX13501.1 - 1.6e-25 89.8 0.0 2e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 GAX13501.1 - 1.4e-18 67.2 0.0 1.6e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_25 PF13649.6 GAX13501.1 - 2e-06 28.4 0.1 3.5e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX13501.1 - 0.0014 19.2 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX13501.1 - 0.0034 17.2 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX13501.1 - 0.02 15.6 0.0 0.036 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAX13501.1 - 0.036 13.6 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 GAX13501.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Lactamase_B PF00753.27 GAX13502.1 - 5.5e-13 49.4 4.5 1.3e-11 44.8 4.5 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAX13502.1 - 0.12 11.9 0.4 0.21 11.1 0.4 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lin0512_fam PF09585.10 GAX13503.1 - 8.2e-25 87.1 0.1 7.4e-24 84.0 0.1 1.9 1 1 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) OB_Dis3 PF17849.1 GAX13503.1 - 0.11 12.5 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) TPR_2 PF07719.17 GAX13505.1 - 3.1e-06 26.9 0.6 0.0042 17.1 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX13505.1 - 5.5e-05 22.8 0.2 0.16 11.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX13505.1 - 0.00024 21.6 0.2 0.016 16.0 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX13505.1 - 0.00031 21.2 0.1 0.00065 20.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX13505.1 - 0.00034 20.2 0.0 0.0009 18.9 0.0 1.8 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.6 GAX13505.1 - 0.00038 20.7 0.8 0.012 15.8 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX13505.1 - 0.0025 18.1 0.2 0.066 13.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX13505.1 - 0.0027 18.3 0.1 0.0079 16.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX13505.1 - 0.019 15.6 0.2 2 9.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX13505.1 - 0.077 13.2 1.1 0.89 9.9 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX13505.1 - 0.1 12.7 0.1 3.7 7.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 GAX13505.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_9 PF13371.6 GAX13505.1 - 0.14 12.3 0.1 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Band_7 PF01145.25 GAX13506.1 - 4.6e-23 82.2 0.3 6.4e-23 81.7 0.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 GAX13506.1 - 0.017 14.2 0.7 0.024 13.7 0.7 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial DnaJ PF00226.31 GAX13507.1 - 3.4e-11 43.1 0.7 4.6e-11 42.7 0.2 1.5 2 0 0 2 2 2 1 DnaJ domain zf-CSL PF05207.13 GAX13507.1 - 1.3e-05 24.8 2.3 3.6e-05 23.4 2.3 1.8 1 1 0 1 1 1 1 CSL zinc finger Prp18 PF02840.15 GAX13508.1 - 7.3e-60 201.2 0.2 1.6e-59 200.0 0.2 1.6 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 GAX13508.1 - 2.5e-09 36.5 0.7 4.3e-09 35.8 0.7 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like GEMIN8 PF15348.6 GAX13508.1 - 0.1 12.9 4.0 0.16 12.2 4.0 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF4755 PF15947.5 GAX13508.1 - 0.11 12.5 0.3 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4755) DprA_WH PF17782.1 GAX13509.1 - 0.0042 17.2 0.0 0.076 13.1 0.0 2.8 2 0 0 2 2 2 1 DprA winged helix domain Laminin_G_3 PF13385.6 GAX13510.1 - 9.9e-06 25.8 0.0 4.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Big_9 PF17963.1 GAX13510.1 - 0.081 13.7 0.8 0.28 11.9 0.8 1.9 1 0 0 1 1 1 0 Bacterial Ig domain LSM14 PF12701.7 GAX13510.1 - 0.084 13.0 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Scd6-like Sm domain tRNA-synt_2b PF00587.25 GAX13511.1 - 4.9e-30 104.8 0.0 4.7e-29 101.6 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAX13511.1 - 5.8e-13 49.0 7.5 1.1e-12 48.2 7.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 GAX13511.1 - 0.055 12.3 4.9 0.09 11.6 4.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 GAX13511.1 - 0.094 12.8 8.3 0.32 11.1 8.3 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 GAX13511.1 - 0.11 11.9 3.9 0.18 11.1 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 GAX13511.1 - 3 7.1 4.8 4.8 6.4 4.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cellulase PF00150.18 GAX13512.1 - 2.7e-35 122.2 7.9 5e-35 121.3 7.9 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_6 PF03422.15 GAX13512.1 - 2.5e-21 76.3 1.0 5e-21 75.3 1.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX13512.1 - 6.8e-11 42.3 0.5 1.4e-10 41.3 0.5 1.5 1 0 0 1 1 1 1 DUF5010 C-terminal domain DprA_WH PF17782.1 GAX13512.1 - 0.097 12.8 0.1 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 DprA winged helix domain DAO PF01266.24 GAX13514.1 - 6.2e-31 108.3 0.1 7.2e-31 108.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX13514.1 - 7.3e-05 22.8 0.2 0.00019 21.4 0.2 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAX13514.1 - 0.00043 20.5 0.3 0.00089 19.4 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX13514.1 - 0.0058 15.8 0.4 0.009 15.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 GAX13514.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GAX13514.1 - 0.14 11.4 0.2 0.31 10.3 0.2 1.5 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 GAX13514.1 - 0.15 10.9 0.1 0.44 9.3 0.1 1.7 2 0 0 2 2 2 0 MCRA family Trypsin PF00089.26 GAX13515.1 - 2.4e-08 34.1 0.1 5.9e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX13515.1 - 7.8e-08 33.4 0.0 1.6e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Methyltransf_31 PF13847.6 GAX13517.1 - 8.4e-29 100.3 0.0 2.2e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX13517.1 - 6.2e-24 84.5 0.0 1.4e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX13517.1 - 8.8e-24 84.0 0.0 1.7e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cofac_haem_bdg PF04187.13 GAX13517.1 - 7.3e-23 81.7 0.1 1.8e-22 80.4 0.0 1.7 2 0 0 2 2 2 1 Haem-binding uptake, Tiki superfamily, ChaN Methyltransf_23 PF13489.6 GAX13517.1 - 1.2e-15 57.7 0.0 2.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX13517.1 - 1.3e-14 54.1 0.0 2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX13517.1 - 4.6e-13 49.7 0.0 1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX13517.1 - 3.3e-11 43.0 0.0 5.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 GAX13517.1 - 1.6e-09 37.8 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAX13517.1 - 1.9e-08 34.0 0.0 4.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX13517.1 - 6.6e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 GAX13517.1 - 2.4e-06 27.6 0.0 4.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAX13517.1 - 3.2e-05 23.9 0.0 0.0001 22.2 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase UPF0020 PF01170.18 GAX13517.1 - 5e-05 23.1 0.0 0.00014 21.6 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 FtsJ PF01728.19 GAX13517.1 - 0.00079 19.6 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.11 GAX13517.1 - 0.00089 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 GAX13517.1 - 0.0011 18.4 0.0 0.0042 16.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 GAX13517.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 GAX13517.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Erythro_esteras PF05139.14 GAX13517.1 - 0.012 15.4 1.2 0.13 12.1 0.0 2.7 2 1 1 3 3 3 0 Erythromycin esterase Pox_MCEL PF03291.16 GAX13517.1 - 0.042 12.9 0.0 0.11 11.5 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme FdtA PF05523.11 GAX13517.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 WxcM-like, C-terminal Methyltransf_18 PF12847.7 GAX13517.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Silic_transp PF03842.13 GAX13518.1 - 1.1e-156 522.1 22.1 1.4e-156 521.8 22.1 1.0 1 0 0 1 1 1 1 Silicon transporter DUF2207 PF09972.9 GAX13518.1 - 5.9 5.5 7.0 24 3.5 4.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SNF2_N PF00176.23 GAX13520.1 - 1.1e-68 231.5 0.0 1.9e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAX13520.1 - 2.6e-34 117.7 4.0 1.1e-29 102.8 0.1 2.8 1 1 1 2 2 2 2 SLIDE Helicase_C PF00271.31 GAX13520.1 - 2.9e-19 69.4 0.0 8.3e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX13520.1 - 4.9e-10 39.7 0.0 1.6e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX13520.1 - 7.9e-05 22.5 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HAND PF09110.11 GAX13520.1 - 0.00017 22.3 1.3 0.00017 22.3 1.3 2.9 2 0 0 2 2 1 1 HAND SWI2_SNF2 PF18766.1 GAX13520.1 - 0.0023 17.7 0.0 0.006 16.3 0.0 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 GAX13520.1 - 0.015 14.5 0.0 0.037 13.2 0.0 1.8 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 GAX13520.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 GAX13520.1 - 0.084 12.9 0.0 0.55 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DBINO PF13892.6 GAX13520.1 - 0.1 13.0 0.0 0.1 13.0 0.0 3.5 4 0 0 4 4 4 0 DNA-binding domain CRAL_TRIO PF00650.20 GAX13521.1 - 4.5e-26 91.5 0.2 7.5e-26 90.8 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX13521.1 - 0.0002 21.5 0.1 0.00039 20.6 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CppA_C PF14507.6 GAX13521.1 - 0.071 13.8 0.1 0.15 12.8 0.1 1.5 1 0 0 1 1 1 0 CppA C-terminal FAM176 PF14851.6 GAX13521.1 - 0.95 9.1 3.9 2 8.1 3.9 1.5 1 0 0 1 1 1 0 FAM176 family AAA_12 PF13087.6 GAX13522.1 - 2.2e-19 69.9 0.0 4.4e-18 65.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX13522.1 - 6.9e-14 52.3 5.8 1.1e-06 28.7 0.3 3.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 GAX13522.1 - 2.5e-07 30.6 0.0 9.3e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAX13522.1 - 5.8e-05 23.5 0.0 0.0025 18.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 GAX13522.1 - 0.019 14.5 0.3 0.043 13.3 0.3 1.8 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain PspB PF06667.12 GAX13522.1 - 0.046 13.8 0.1 0.16 12.0 0.1 2.0 1 0 0 1 1 1 0 Phage shock protein B DUF2075 PF09848.9 GAX13522.1 - 0.049 12.9 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 GAX13522.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MTES_1575 PF18741.1 GAX13522.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 REase_MTES_1575 AAA_16 PF13191.6 GAX13522.1 - 0.084 13.3 0.0 0.31 11.4 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAX13522.1 - 0.13 12.5 0.2 0.64 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 GAX13522.1 - 0.18 11.8 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit tRNA_U5-meth_tr PF05958.11 GAX13523.1 - 1.7e-23 83.2 0.1 1.2e-22 80.4 0.1 2.1 1 1 1 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 GAX13523.1 - 1.3e-05 25.8 0.0 3.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX13523.1 - 1.7e-05 24.7 0.1 3.5e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX13523.1 - 4.3e-05 23.1 0.0 7.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX13523.1 - 0.0001 21.8 0.2 0.00018 21.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 GAX13523.1 - 0.00089 18.9 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 GAX13523.1 - 0.0021 18.7 0.0 0.0043 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX13523.1 - 0.0058 16.3 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TRM PF02005.16 GAX13523.1 - 0.029 13.5 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RsmJ PF04378.13 GAX13523.1 - 0.032 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ DUF4952 PF16310.5 GAX13523.1 - 0.045 14.0 0.0 7.6 6.9 0.0 3.1 3 0 0 3 3 3 0 Domian of unknown function (DUF4952) Methyltransf_4 PF02390.17 GAX13523.1 - 0.046 13.2 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 GAX13523.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 GAX13523.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PHD_2 PF13831.6 GAX13524.1 - 0.00012 21.6 4.0 0.00012 21.6 4.0 2.7 2 0 0 2 2 2 1 PHD-finger Ribosomal_S10 PF00338.22 GAX13525.1 - 0.075 13.3 0.2 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e PPR_2 PF13041.6 GAX13527.1 - 6.7e-38 128.7 6.6 6.2e-14 51.9 0.3 7.9 8 2 2 10 10 9 3 PPR repeat family PPR_3 PF13812.6 GAX13527.1 - 3.1e-29 100.8 5.5 4.5e-07 29.8 0.1 6.7 6 1 1 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 GAX13527.1 - 1.4e-23 81.4 6.9 6.2e-05 23.0 0.0 9.5 10 1 0 10 10 10 4 PPR repeat PPR_1 PF12854.7 GAX13527.1 - 5e-13 48.5 3.8 3.7e-05 23.3 0.0 7.3 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 GAX13527.1 - 5.6e-10 38.9 4.6 1.2e-05 24.8 0.1 3.4 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PDZ PF00595.24 GAX13527.1 - 2.1e-07 31.2 0.0 0.0061 16.9 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 GAX13527.1 - 1.1e-06 28.9 0.0 0.0008 19.7 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 GAX13527.1 - 0.0024 17.7 0.4 0.4 10.6 0.0 3.1 3 0 0 3 3 3 1 PDZ domain MNE1 PF13762.6 GAX13527.1 - 0.0044 17.0 2.0 0.012 15.6 1.5 2.0 1 1 0 1 1 1 1 Mitochondrial splicing apparatus component Mic1 PF07035.12 GAX13527.1 - 0.03 14.0 0.8 6.2 6.5 0.0 3.0 2 1 1 3 3 3 0 Colon cancer-associated protein Mic1-like Gal11_ABD1 PF18535.1 GAX13527.1 - 0.056 13.5 0.9 0.42 10.7 0.1 2.4 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) PCI PF01399.27 GAX13527.1 - 0.062 13.8 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 PCI domain Rad60-SLD PF11976.8 GAX13528.1 - 3.3e-16 58.9 0.5 3.7e-16 58.7 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAX13528.1 - 4e-08 32.9 0.2 4.5e-08 32.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX13529.1 - 1.5e-16 60.0 0.4 1.7e-16 59.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAX13529.1 - 8e-08 31.9 0.3 8.8e-08 31.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Cation_efflux PF01545.21 GAX13531.1 - 2.1e-13 50.5 0.1 3.8e-13 49.6 0.1 1.3 1 1 0 1 1 1 1 Cation efflux family HMG_box PF00505.19 GAX13532.1 - 4.6e-55 183.9 10.0 3.1e-19 69.1 1.6 3.2 3 0 0 3 3 3 3 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX13532.1 - 3.9e-37 126.7 9.8 2.3e-15 56.9 0.0 3.3 3 0 0 3 3 3 3 HMG-box domain CHDNT PF08073.12 GAX13532.1 - 3.7e-08 33.2 0.2 0.015 15.2 0.0 3.4 3 0 0 3 3 3 3 CHDNT (NUC034) domain HMG_box_5 PF14887.6 GAX13532.1 - 4.8e-08 32.9 0.1 0.25 11.3 0.0 3.4 3 0 0 3 3 3 3 HMG (high mobility group) box 5 Ccdc124 PF06244.12 GAX13532.1 - 6.3e-07 30.0 0.8 0.007 16.9 0.1 3.4 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 124 /Oxs1 HTH_IclR PF09339.10 GAX13532.1 - 0.21 11.4 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain APA3_viroporin PF11289.8 GAX13533.1 - 0.056 13.0 0.2 4 6.9 0.1 2.0 1 1 1 2 2 2 0 Coronavirus accessory protein 3a Ribosomal_L18A PF01775.17 GAX13535.1 - 3.4e-49 165.9 0.3 4.4e-49 165.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Inhibitor_I29 PF08246.12 GAX13535.1 - 0.028 14.8 0.7 0.087 13.3 0.7 1.9 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) DUF3730 PF12530.8 GAX13536.1 - 0.0075 15.9 1.3 0.016 14.8 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3730) DUF2956 PF11169.8 GAX13536.1 - 0.18 12.0 2.4 0.22 11.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) MOLO1 PF17175.4 GAX13537.1 - 2.1e-16 60.1 0.4 6.1e-16 58.6 0.2 1.9 2 0 0 2 2 2 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 GAX13537.1 - 8.7e-14 51.8 0.0 6.6e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 TPM domain zf-RING_2 PF13639.6 GAX13537.1 - 1.9e-10 40.9 3.6 1.9e-10 40.9 3.6 2.7 3 1 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX13537.1 - 7.6e-08 32.2 0.4 7.6e-08 32.2 0.4 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAX13537.1 - 2.5e-06 27.7 2.3 2.5e-06 27.7 2.3 2.7 3 0 0 3 3 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAX13537.1 - 2.8e-06 27.1 5.2 0.00013 21.7 2.3 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAX13537.1 - 1.2e-05 25.0 1.2 1.2e-05 25.0 1.2 2.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 GAX13537.1 - 5e-05 23.0 2.1 0.004 16.9 0.7 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 GAX13537.1 - 5.4e-05 22.9 7.7 0.001 18.9 0.3 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FixQ PF05545.11 GAX13537.1 - 6.2e-05 22.9 1.0 0.0023 17.8 0.0 2.4 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ zf-RING_5 PF14634.6 GAX13537.1 - 8.6e-05 22.4 0.8 8.6e-05 22.4 0.8 2.8 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX13537.1 - 0.00077 19.3 3.9 0.00077 19.3 3.9 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX13537.1 - 0.00081 19.4 3.5 0.00081 19.4 3.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 GAX13537.1 - 0.0054 16.4 10.1 0.022 14.5 0.3 4.2 3 1 0 3 3 3 1 RING-like zinc finger HemX PF04375.14 GAX13537.1 - 0.015 14.6 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase zf-C3HC4_4 PF15227.6 GAX13537.1 - 0.018 15.2 4.2 0.25 11.5 0.4 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Pellino PF04710.14 GAX13537.1 - 0.022 13.4 0.9 0.042 12.5 0.9 1.4 1 1 0 1 1 1 0 Pellino DUF4131 PF13567.6 GAX13537.1 - 0.055 13.1 0.0 7.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ion_trans PF00520.31 GAX13537.1 - 0.093 11.9 0.2 0.39 9.9 0.2 1.9 1 1 0 1 1 1 0 Ion transport protein Rtf2 PF04641.12 GAX13537.1 - 0.13 11.6 0.0 0.5 9.7 0.0 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger PDR_CDR PF06422.12 GAX13537.1 - 0.13 12.1 2.5 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 CDR ABC transporter EMC3_TMCO1 PF01956.16 GAX13537.1 - 0.2 11.4 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FANCL_C PF11793.8 GAX13537.1 - 1 9.6 8.4 1.4 9.2 4.4 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX13537.1 - 1 9.0 4.5 0.49 10.0 1.8 1.9 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type NOA36 PF06524.12 GAX13538.1 - 5.4 6.2 12.2 8.8 5.5 12.2 1.3 1 0 0 1 1 1 0 NOA36 protein LYRIC PF15686.5 GAX13539.1 - 0.025 14.1 7.6 0.035 13.7 7.6 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family FYDLN_acid PF09538.10 GAX13539.1 - 0.54 11.0 9.8 0.59 10.8 8.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PBP_sp32 PF07222.12 GAX13539.1 - 0.62 9.5 3.5 0.88 9.0 3.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pkinase PF00069.25 GAX13540.1 - 1.7e-56 191.5 0.0 3e-56 190.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX13540.1 - 3.4e-39 132.8 0.8 1e-16 60.8 0.0 4.2 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX13540.1 - 4.4e-25 88.4 0.0 7.4e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX13540.1 - 0.047 13.6 0.9 1.5 8.7 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cupin_2 PF07883.11 GAX13540.1 - 0.075 12.8 0.7 2.1 8.1 0.0 3.2 4 0 0 4 4 4 0 Cupin domain Kinase-like PF14531.6 GAX13540.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 GAX13540.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_transf_7C PF02709.14 GAX13541.1 - 0.012 15.2 0.3 0.035 13.7 0.3 1.8 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Inhibitor_I9 PF05922.16 GAX13543.1 - 0.094 13.4 0.0 1.6 9.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I9 UvrC_HhH_N PF08459.11 GAX13544.1 - 3.5e-41 140.7 0.0 7.4e-41 139.6 0.0 1.6 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal Helicase_C PF00271.31 GAX13544.1 - 7.6e-12 45.6 0.0 2.2e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UvrB PF12344.8 GAX13544.1 - 3.1e-11 42.9 0.1 7.9e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Ultra-violet resistance protein B ResIII PF04851.15 GAX13544.1 - 9e-09 35.6 0.0 3.6e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GIY-YIG PF01541.24 GAX13544.1 - 2.1e-06 27.9 0.0 6.9e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA_30 PF13604.6 GAX13544.1 - 0.00085 19.1 0.0 0.0068 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain UvrB_inter PF17757.1 GAX13544.1 - 0.0027 17.8 0.0 0.0061 16.7 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 GAX13544.1 - 0.003 17.3 0.1 0.038 13.8 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GAX13544.1 - 0.014 15.7 0.1 2.3 8.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF496 PF04363.12 GAX13544.1 - 0.016 15.2 2.1 1 9.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF496) AAA_22 PF13401.6 GAX13544.1 - 0.017 15.4 0.0 0.056 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAX13544.1 - 0.027 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 GAX13544.1 - 0.032 14.6 0.1 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain TPR_19 PF14559.6 GAX13545.1 - 0.0099 16.4 0.2 0.092 13.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat PhoD PF09423.10 GAX13546.1 - 2.1e-16 59.9 0.1 7.1e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Rtf2 PF04641.12 GAX13547.1 - 1.8e-28 99.7 0.1 2.5e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger PP2C PF00481.21 GAX13548.1 - 1.6e-14 54.2 0.1 8.1e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C DUF4884 PF16225.5 GAX13548.1 - 0.083 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) PP2C PF00481.21 GAX13549.1 - 4.1e-24 85.6 0.0 9.8e-24 84.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Sod_Fe_C PF02777.18 GAX13553.1 - 1.5e-37 127.8 0.0 3.2e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAX13553.1 - 4.9e-28 97.4 0.5 1.2e-27 96.2 0.5 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain PDR_CDR PF06422.12 GAX13554.1 - 0.013 15.4 0.6 2.7 7.9 0.0 2.6 2 1 1 3 3 3 0 CDR ABC transporter TauE PF01925.19 GAX13554.1 - 0.022 14.4 0.2 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE SPT_ssu-like PF11779.8 GAX13554.1 - 0.094 12.3 1.9 2.2 7.9 0.5 2.6 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like DUF2304 PF10066.9 GAX13554.1 - 0.57 10.4 5.1 2.8 8.2 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) HECT PF00632.25 GAX13555.1 - 6.2e-89 298.5 0.0 9.9e-89 297.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 GAX13555.1 - 1.3e-42 146.6 2.8 1.1e-26 94.2 0.2 3.7 3 0 0 3 3 3 2 Domain of Unknown Function (DUF908) DUF913 PF06025.12 GAX13555.1 - 1.8e-40 139.1 21.5 3.5e-34 118.4 0.2 4.9 4 1 1 5 5 5 2 Domain of Unknown Function (DUF913) UBM PF14377.6 GAX13555.1 - 1.1e-13 50.1 8.3 4.2e-07 29.2 0.2 4.6 3 1 1 4 4 4 3 Ubiquitin binding region UBA PF00627.31 GAX13555.1 - 2.8e-05 23.9 0.2 9.4e-05 22.2 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Peptidase_C42 PF05533.12 GAX13555.1 - 0.047 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 DNA_pol3_beta_3 PF02768.15 GAX13555.1 - 0.13 12.1 0.1 0.43 10.4 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain Hum_adeno_E3A PF05393.11 GAX13555.1 - 0.18 11.8 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein PCI PF01399.27 GAX13556.1 - 4.8e-08 33.5 1.6 4.8e-08 33.5 1.6 3.4 3 1 0 3 3 3 1 PCI domain SAP PF02037.27 GAX13558.1 - 4.8e-12 45.3 2.8 4.8e-12 45.3 2.8 1.8 2 0 0 2 2 2 1 SAP domain Apt1 PF10351.9 GAX13558.1 - 0.071 11.9 2.0 0.087 11.7 2.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tho1_MOS11_C PF18592.1 GAX13558.1 - 0.082 12.7 0.1 0.082 12.7 0.1 3.2 4 1 0 4 4 4 0 Tho1/MOS11 C-terminal domain ROQ_II PF18386.1 GAX13559.1 - 0.11 12.3 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Roquin II domain bZIP_1 PF00170.21 GAX13560.1 - 0.02 15.0 0.7 0.02 15.0 0.7 5.2 4 1 0 4 4 4 0 bZIP transcription factor TolA_bind_tri PF16331.5 GAX13560.1 - 0.022 14.8 1.3 0.022 14.8 1.3 3.4 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF5340 PF17275.2 GAX13560.1 - 0.027 14.6 2.1 0.096 12.8 2.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5340) Cep57_CLD_2 PF14197.6 GAX13560.1 - 0.2 11.8 20.2 0.25 11.5 6.3 3.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 SOGA PF11365.8 GAX13560.1 - 1.8 9.7 15.9 0.56 11.4 3.6 3.3 2 1 1 3 3 3 0 Protein SOGA Spc7 PF08317.11 GAX13560.1 - 4.1 6.2 20.0 6.3 5.6 19.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 GAX13560.1 - 4.2 7.2 22.2 2 8.2 0.5 3.7 1 1 2 3 3 3 0 Septum formation initiator BLOC1_2 PF10046.9 GAX13560.1 - 4.5 7.7 12.0 36 4.8 8.7 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1995 PF09353.10 GAX13561.1 - 4.1e-31 108.6 0.1 2.7e-30 105.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) Sigma70_r1_1 PF03979.14 GAX13561.1 - 0.00093 19.2 9.3 0.0019 18.2 7.2 2.6 2 1 0 2 2 2 1 Sigma-70 factor, region 1.1 CDC37_C PF08564.10 GAX13561.1 - 0.0019 18.3 4.4 0.0036 17.4 0.1 3.0 3 0 0 3 3 3 1 Cdc37 C terminal domain DsrC PF04358.13 GAX13561.1 - 0.07 13.7 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 DsrC like protein AsiA PF09010.10 GAX13561.1 - 0.079 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Anti-Sigma Factor A DEK_C PF08766.11 GAX13561.1 - 0.08 12.9 0.2 6.9 6.7 0.0 3.2 3 0 0 3 3 3 0 DEK C terminal domain DUF16 PF01519.16 GAX13561.1 - 0.46 11.0 2.5 0.29 11.7 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 GtrA PF04138.14 GAX13563.1 - 0.00026 21.2 9.4 0.00036 20.7 9.4 1.2 1 0 0 1 1 1 1 GtrA-like protein Arginase PF00491.21 GAX13564.1 - 1.3e-69 234.9 0.0 1.6e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family AAA_21 PF13304.6 GAX13565.1 - 0.027 14.3 0.2 0.072 12.9 0.2 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Bombinin PF05298.11 GAX13566.1 - 0.042 13.5 0.8 0.1 12.3 0.3 1.9 2 0 0 2 2 2 0 Bombinin HGTP_anticodon PF03129.20 GAX13566.1 - 0.047 13.8 2.9 0.15 12.2 0.3 2.8 3 0 0 3 3 3 0 Anticodon binding domain DUF2508 PF10704.9 GAX13566.1 - 0.64 10.2 8.1 0.13 12.5 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF2894 PF11445.8 GAX13566.1 - 1.6 9.1 5.6 0.98 9.9 1.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2894) PPR_2 PF13041.6 GAX13567.1 - 1.7e-29 101.8 0.0 1.3e-07 31.6 0.1 7.9 7 1 1 8 8 8 6 PPR repeat family PPR_1 PF12854.7 GAX13567.1 - 1.1e-21 76.2 0.4 0.018 14.7 0.0 9.5 9 0 0 9 9 9 5 PPR repeat PPR PF01535.20 GAX13567.1 - 7.5e-20 69.7 14.8 0.00012 22.1 0.0 10.1 12 0 0 12 12 12 5 PPR repeat PPR_3 PF13812.6 GAX13567.1 - 3e-15 56.0 0.0 0.0067 16.5 0.0 7.3 7 1 1 8 8 8 3 Pentatricopeptide repeat domain TPR_MalT PF17874.1 GAX13567.1 - 0.0012 18.3 5.1 0.003 17.0 0.4 2.7 3 0 0 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 GAX13567.1 - 0.11 13.4 6.2 19 6.4 0.0 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat DEAD PF00270.29 GAX13568.1 - 4.1e-11 42.9 0.1 1.3e-10 41.3 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsRBD2 PF17842.1 GAX13568.1 - 2.3e-05 24.6 0.6 8.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding domain 2 AAA_19 PF13245.6 GAX13568.1 - 0.00075 19.9 0.1 0.0028 18.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX13568.1 - 0.0012 19.1 0.1 0.0048 17.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAX13568.1 - 0.027 15.0 14.6 0.42 11.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain DND1_DSRM PF14709.7 GAX13568.1 - 0.15 12.3 0.2 2.2 8.6 0.1 2.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 FlxA PF14282.6 GAX13568.1 - 0.29 11.1 3.0 0.28 11.2 0.1 2.5 2 0 0 2 2 2 0 FlxA-like protein Pro_isomerase PF00160.21 GAX13569.1 - 2.1e-22 80.1 0.0 3.4e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UCH PF00443.29 GAX13571.1 - 2.3e-45 155.1 0.0 2.8e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX13571.1 - 3.8e-14 53.0 0.0 1.7e-12 47.6 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAX13571.1 - 0.019 14.7 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family UIM PF02809.20 GAX13571.1 - 0.1 12.5 2.9 0.41 10.7 2.9 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif SNAP PF14938.6 GAX13572.1 - 2.2e-93 312.8 13.0 2.5e-93 312.6 13.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP NSF PF02071.20 GAX13572.1 - 0.002 18.5 20.9 3.1 9.0 0.2 6.5 7 0 0 7 7 7 2 Aromatic-di-Alanine (AdAR) repeat TPR_MalT PF17874.1 GAX13572.1 - 0.0032 16.9 4.0 0.0033 16.8 0.5 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 GAX13572.1 - 0.037 14.3 12.4 0.4 11.0 0.0 5.0 2 1 4 6 6 6 0 Tetratricopeptide repeat DUF4071 PF13281.6 GAX13572.1 - 0.059 12.4 0.2 0.079 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) TPR_7 PF13176.6 GAX13572.1 - 1.3 9.2 8.6 66 3.9 0.1 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 GAX13572.1 - 1.4 8.0 6.6 2.1 7.3 0.3 2.3 2 0 0 2 2 2 0 Spatacsin C-terminus TPR_10 PF13374.6 GAX13572.1 - 6.6 6.7 5.9 2.3 8.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 GAX13573.1 - 6.1e-49 166.7 0.0 7.7e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX13573.1 - 1e-37 129.5 0.0 1.2e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX13573.1 - 1.1e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX13573.1 - 0.0021 17.6 0.5 0.012 15.1 0.5 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cyclin_N PF00134.23 GAX13574.1 - 6e-22 77.7 0.0 1e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX13574.1 - 1.3e-14 54.2 0.0 2.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zip PF02535.22 GAX13575.1 - 2e-41 142.3 5.0 2.5e-41 142.0 5.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.20 GAX13575.1 - 0.028 13.9 0.0 0.028 13.9 0.0 2.3 3 0 0 3 3 3 0 E1-E2 ATPase GNT-I PF03071.15 GAX13576.1 - 4.1e-80 269.7 0.0 5.1e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 GAX13576.1 - 0.00021 21.2 0.0 0.00065 19.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 MGAT2 PF05060.14 GAX13576.1 - 0.049 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) PMSR PF01625.21 GAX13577.1 - 2.7e-45 154.3 0.5 3.9e-45 153.7 0.5 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 GAX13577.1 - 0.0013 19.0 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Exo_endo_phos PF03372.23 GAX13578.1 - 2.8e-12 46.6 0.0 4.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_11 PF13414.6 GAX13579.1 - 0.0021 17.7 2.0 0.15 11.8 0.1 2.7 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.6 GAX13579.1 - 0.018 14.9 4.5 0.14 12.1 0.9 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX13579.1 - 0.024 14.7 3.6 0.13 12.4 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Corona_NSP4_C PF16348.5 GAX13579.1 - 0.035 14.9 0.2 0.062 14.1 0.2 1.3 1 0 0 1 1 1 0 Coronavirus nonstructural protein 4 C-terminus TPR_7 PF13176.6 GAX13579.1 - 0.11 12.5 1.4 3.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX13579.1 - 0.14 12.4 1.8 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX13579.1 - 0.26 11.2 0.1 0.26 11.2 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zinc_ribbon_6 PF14599.6 GAX13580.1 - 1.7e-16 60.0 0.2 1.7e-16 60.0 0.2 4.0 3 1 1 4 4 3 1 Zinc-ribbon zf-CHY PF05495.12 GAX13580.1 - 3.2e-14 53.2 16.7 3.2e-14 53.2 16.7 5.0 2 2 0 2 2 1 1 CHY zinc finger zf-RING_2 PF13639.6 GAX13580.1 - 1.5e-08 34.8 7.7 1.5e-08 34.8 7.7 5.1 5 1 0 5 5 4 1 Ring finger domain zf-RING_5 PF14634.6 GAX13580.1 - 9.3e-06 25.5 6.2 9.3e-06 25.5 6.2 5.6 4 3 2 7 7 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAX13580.1 - 1.4e-05 24.8 6.5 1.4e-05 24.8 6.5 5.3 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX13580.1 - 0.00015 21.7 1.0 0.00015 21.7 1.0 4.9 5 1 1 6 6 4 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX13580.1 - 0.00028 20.7 6.5 0.00028 20.7 6.5 5.8 3 1 2 5 5 3 2 Zinc finger, C3HC4 type (RING finger) Rubredoxin_2 PF18073.1 GAX13580.1 - 0.032 14.0 0.3 0.032 14.0 0.3 6.8 7 1 0 7 7 7 0 Rubredoxin metal binding domain Rad50_zn_hook PF04423.14 GAX13580.1 - 0.062 13.1 1.0 3.7 7.5 0.1 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-WRNIP1_ubi PF18279.1 GAX13580.1 - 0.15 12.7 12.6 8 7.4 0.0 5.8 5 1 0 5 5 5 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF4599 PF15371.6 GAX13580.1 - 0.16 12.6 1.6 0.34 11.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) IlvGEDA_leader PF08046.11 GAX13580.1 - 2.6 7.6 4.6 6.3 6.3 4.6 1.6 1 0 0 1 1 1 0 IlvGEDA operon leader peptide XPG_I PF00867.18 GAX13581.1 - 4.1e-12 46.3 0.3 5.5e-11 42.7 0.3 2.5 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAX13581.1 - 2.1e-11 44.2 0.1 8.3e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 GAX13581.1 - 7.5e-05 22.3 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing Nkap_C PF06047.11 GAX13582.1 - 1.4e-44 150.4 2.9 1.4e-44 150.4 2.9 2.5 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain S1 PF00575.23 GAX13582.1 - 5.1e-12 46.0 0.2 1.2e-11 44.7 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 GAX13582.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 S1 domain GREB1 PF15782.5 GAX13582.1 - 0.71 6.9 17.9 1 6.4 17.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 GAX13582.1 - 2.2 6.9 14.2 3.2 6.3 14.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.6 GAX13582.1 - 2.5 8.6 24.0 0.16 12.6 18.5 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein Apt1 PF10351.9 GAX13582.1 - 3.3 6.5 35.8 0.022 13.7 21.8 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain PseudoU_synth_2 PF00849.22 GAX13583.1 - 1.3e-12 48.1 0.1 2.4e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase WW PF00397.26 GAX13585.1 - 4.7e-09 36.2 3.6 1e-08 35.1 3.6 1.6 1 0 0 1 1 1 1 WW domain CLN3 PF02487.17 GAX13586.1 - 1.6e-71 241.4 7.6 1.9e-71 241.2 7.6 1.0 1 0 0 1 1 1 1 CLN3 protein Strabismus PF06638.11 GAX13587.1 - 0.049 12.3 0.1 0.071 11.7 0.1 1.2 1 0 0 1 1 1 0 Strabismus protein Metallophos PF00149.28 GAX13588.1 - 2.9e-05 24.6 0.0 3.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IMS PF00817.20 GAX13589.1 - 4.2e-34 117.7 0.3 6.7e-34 117.1 0.3 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 GAX13589.1 - 0.05 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif Put_Phosphatase PF06888.12 GAX13590.1 - 7.4e-52 176.1 0.0 8.5e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 GAX13590.1 - 2.4e-09 37.9 0.0 4.2e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX13590.1 - 0.00018 21.7 1.3 0.0017 18.5 1.5 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DHHC PF01529.20 GAX13591.1 - 3.1e-12 46.8 1.9 4.2e-11 43.1 0.0 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase Syntaxin-6_N PF09177.11 GAX13592.1 - 1e-12 48.5 7.3 1.1e-12 48.3 1.0 2.6 2 1 0 2 2 2 1 Syntaxin 6, N-terminal DUF5446 PF17522.2 GAX13592.1 - 0.012 15.7 0.1 0.012 15.7 0.1 2.2 3 1 0 3 3 2 0 Family of unknown function (DUF5446) V-SNARE PF05008.15 GAX13592.1 - 0.017 15.5 7.3 1.2 9.6 1.0 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus KxDL PF10241.9 GAX13592.1 - 0.019 15.2 1.8 0.019 15.2 1.8 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein SlyX PF04102.12 GAX13592.1 - 0.02 15.5 2.6 0.02 15.5 2.6 3.1 2 2 1 3 3 3 0 SlyX SNARE PF05739.19 GAX13592.1 - 0.043 13.8 0.4 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 SNARE domain Sec20 PF03908.13 GAX13592.1 - 0.055 13.4 8.0 2.2 8.3 0.4 3.0 2 1 1 3 3 3 0 Sec20 DUF1664 PF07889.12 GAX13592.1 - 0.056 13.5 9.4 0.96 9.5 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Chrome_Resist PF09828.9 GAX13592.1 - 0.076 13.5 0.2 0.22 12.0 0.2 1.7 1 0 0 1 1 1 0 Chromate resistance exported protein TMPIT PF07851.13 GAX13592.1 - 0.16 11.2 6.4 0.2 10.9 0.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 GAX13592.1 - 0.2 11.9 7.6 9.2 6.6 0.8 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 GAX13592.1 - 0.32 11.0 10.0 7.8 6.5 0.6 3.5 3 1 1 4 4 4 0 Laminin Domain II DUF1043 PF06295.12 GAX13592.1 - 1.4 8.9 7.5 4.9 7.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) XhlA PF10779.9 GAX13592.1 - 3.3 8.0 5.7 14 6.0 0.6 2.9 2 1 1 3 3 3 0 Haemolysin XhlA DNA_ligase_aden PF01653.18 GAX13593.1 - 0.0048 16.0 0.1 0.23 10.5 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent DNA ligase adenylation domain TF_Zn_Ribbon PF08271.12 GAX13593.1 - 0.011 15.2 5.0 0.017 14.7 0.4 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding SHOCT PF09851.9 GAX13593.1 - 0.049 13.4 1.2 6.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Short C-terminal domain PhnA_Zn_Ribbon PF08274.12 GAX13593.1 - 0.056 13.4 1.1 3.1 7.8 0.3 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Sel_put PF04328.13 GAX13593.1 - 0.064 13.3 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Selenoprotein, putative zinc_ribbon_4 PF13717.6 GAX13593.1 - 0.38 10.7 4.8 0.38 10.7 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain GTP_EFTU PF00009.27 GAX13594.1 - 1.9e-24 86.3 0.1 3e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAX13594.1 - 9.5e-07 28.9 0.0 2.5e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX13594.1 - 1.9e-05 24.6 0.7 0.073 13.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 GAX13594.1 - 0.0062 16.8 0.1 3.6 7.8 0.1 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GAX13594.1 - 0.031 14.1 0.1 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 GAX13594.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Dynamin family Septin PF00735.18 GAX13594.1 - 0.13 11.6 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin DHHC PF01529.20 GAX13595.1 - 9.7e-14 51.6 0.2 3.3e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-Y PF15159.6 GAX13595.1 - 0.075 14.0 0.2 0.075 14.0 0.2 2.3 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Tenui_NS4 PF03300.13 GAX13595.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Tenuivirus non-structural, movement protein NS4 UL41A PF17591.2 GAX13595.1 - 0.21 11.7 1.8 1.3 9.2 0.0 2.7 3 0 0 3 3 3 0 Herpesvirus UL41A HA PF03457.14 GAX13596.1 - 1.5e-50 169.3 17.0 1.4e-13 51.0 1.0 4.6 4 0 0 4 4 4 4 Helicase associated domain TUDOR_5 PF18359.1 GAX13596.1 - 6.2e-08 32.2 1.9 0.0018 17.9 0.2 2.7 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 DUF3303 PF11746.8 GAX13596.1 - 0.024 14.9 0.0 14 6.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) LBR_tudor PF09465.10 GAX13596.1 - 0.5 10.2 2.4 5.8 6.8 0.6 2.6 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DHHC PF01529.20 GAX13597.1 - 6.3e-15 55.5 0.6 6.3e-15 55.5 0.6 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Pro_isomerase PF00160.21 GAX13598.1 - 2e-06 28.1 0.0 4.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RVT_2 PF07727.14 GAX13599.1 - 4.2e-23 82.2 0.0 7.3e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chloroa_b-bind PF00504.21 GAX13600.1 - 1.1e-37 130.0 0.2 1.4e-37 129.7 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PPC PF04151.15 GAX13601.1 - 6.5 7.9 9.9 3.6 8.7 1.0 2.7 1 1 1 2 2 2 0 Bacterial pre-peptidase C-terminal domain Polysacc_deac_1 PF01522.21 GAX13602.1 - 0.00018 21.4 0.0 0.0012 18.7 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide deacetylase Na_Ala_symp PF01235.17 GAX13603.1 - 0.057 12.7 0.0 0.062 12.6 0.0 1.0 1 0 0 1 1 1 0 Sodium:alanine symporter family Glyco_transf_49 PF13896.6 GAX13604.1 - 8.1e-45 153.6 0.5 9e-38 130.4 0.2 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAX13604.1 - 0.0073 16.1 0.0 0.054 13.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 GAX13604.1 - 0.045 14.3 0.1 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_49 PF13896.6 GAX13605.1 - 1.4e-39 136.4 0.0 2.1e-36 125.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAX13605.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 XK-related PF09815.9 GAX13607.1 - 0.13 11.3 2.9 1.2 8.1 3.2 2.1 1 1 0 1 1 1 0 XK-related protein DUF2663 PF10864.8 GAX13607.1 - 0.19 12.2 0.9 4.6 7.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) DUF4131 PF13567.6 GAX13607.1 - 0.97 9.1 8.6 0.092 12.4 1.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) TPR_12 PF13424.6 GAX13609.1 - 0.024 14.9 0.5 5.1 7.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RIG-I_C-RD PF11648.8 GAX13609.1 - 0.092 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I Abhydrolase_6 PF12697.7 GAX13612.1 - 2.3e-06 28.4 1.4 3.6e-06 27.8 1.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAX13612.1 - 3.5e-06 26.9 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAX13612.1 - 2e-05 24.2 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 GAX13612.1 - 0.061 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 GAX13612.1 - 0.23 11.0 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase U-box PF04564.15 GAX13613.1 - 2e-19 69.5 0.1 3.4e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GAX13613.1 - 4.1e-07 29.7 2.0 1.4e-06 28.0 0.8 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 GAX13613.1 - 0.00089 19.3 0.3 0.0021 18.0 0.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX13613.1 - 0.00096 19.1 0.2 0.0022 18.0 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAX13613.1 - 0.0018 18.5 0.5 0.0018 18.5 0.5 2.2 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX13613.1 - 0.0055 16.5 0.5 0.014 15.3 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 GAX13613.1 - 0.011 15.1 0.6 0.047 13.1 0.6 1.8 1 1 0 1 1 1 0 Rtf2 RING-finger zf-NOSIP PF15906.5 GAX13613.1 - 0.019 15.1 0.1 0.049 13.8 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Ish1 PF10281.9 GAX13613.1 - 0.023 15.0 0.2 1.6 9.1 0.2 2.8 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein DOCK-C2 PF14429.6 GAX13614.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Guanylate_cyc PF00211.20 GAX13615.1 - 3.5e-42 144.1 0.0 6e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX13615.1 - 3.1e-35 122.0 3.2 7.5e-35 120.8 1.3 2.4 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 GAX13615.1 - 0.00028 20.9 0.0 0.00074 19.5 0.0 1.7 1 0 0 1 1 1 1 CHASE domain DUF1624 PF07786.12 GAX13615.1 - 0.075 12.6 0.2 0.47 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1624) Peripla_BP_4 PF13407.6 GAX13616.1 - 3.4e-42 144.8 0.1 4.6e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain 7tm_3 PF00003.22 GAX13616.1 - 2.9e-37 128.6 16.2 4e-37 128.2 16.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Frag1 PF10277.9 GAX13616.1 - 0.00025 20.7 4.6 0.00025 20.7 4.6 1.9 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Peripla_BP_1 PF00532.21 GAX13616.1 - 0.045 13.2 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PucR PF07905.11 GAX13616.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family PDZ PF00595.24 GAX13617.1 - 2.2e-05 24.7 0.0 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX13617.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX13617.1 - 0.0021 18.4 1.3 0.004 17.4 0.1 2.1 2 0 0 2 2 2 1 PDZ domain Sigma70_r2 PF04542.14 GAX13617.1 - 0.15 11.8 0.0 0.54 10.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-70 region 2 SNARE_assoc PF09335.11 GAX13618.1 - 6e-16 59.0 10.4 6e-16 59.0 10.4 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF996 PF06195.13 GAX13618.1 - 0.92 9.8 10.4 0.43 10.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Arteri_Gl PF00951.18 GAX13618.1 - 6.1 6.6 12.0 0.2 11.4 5.6 1.8 2 1 0 2 2 2 0 Arterivirus GL envelope glycoprotein Robl_LC7 PF03259.17 GAX13619.1 - 0.0087 15.8 0.1 0.02 14.7 0.1 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain Profilin PF00235.19 GAX13619.1 - 0.037 14.3 0.0 0.068 13.4 0.0 1.5 1 1 0 1 1 1 0 Profilin Endonuclease_5 PF04493.14 GAX13620.1 - 2.7e-46 157.8 0.2 2.2e-45 154.8 0.2 1.9 1 1 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 GAX13620.1 - 0.0019 17.6 0.5 0.0077 15.7 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function DUF99 LRR_8 PF13855.6 GAX13621.1 - 0.00047 19.9 4.6 0.0015 18.3 4.7 1.8 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GAX13621.1 - 0.00049 20.4 6.9 0.0014 19.0 2.0 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX13621.1 - 0.0017 18.6 1.9 0.0054 17.0 1.9 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain zf-RING_6 PF14835.6 GAX13621.1 - 0.021 14.7 1.7 0.047 13.6 1.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LRR_1 PF00560.33 GAX13621.1 - 0.11 13.2 3.8 6.3 7.8 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 GAX13622.1 - 9.5e-08 31.7 2.2 1.6e-07 31.0 2.2 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GAX13622.1 - 6e-06 26.5 4.9 0.00016 22.0 0.4 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX13622.1 - 0.00029 21.1 1.1 0.00057 20.1 1.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GAX13622.1 - 0.0017 18.7 0.1 3.8 8.4 0.1 3.7 3 0 0 3 3 3 1 Leucine Rich Repeat BCNT PF07572.12 GAX13623.1 - 7.6e-21 74.0 0.8 1.6e-20 73.0 0.8 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development Nbl1_Borealin_N PF10444.9 GAX13624.1 - 2.7e-05 23.7 8.7 0.00014 21.4 4.9 2.3 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal Borealin PF10512.9 GAX13624.1 - 0.00021 21.2 2.6 0.0023 17.9 0.0 2.9 2 1 1 4 4 4 1 Cell division cycle-associated protein 8 Orthopox_B11R PF07033.11 GAX13624.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Orthopoxvirus B11R protein COPI_assoc PF08507.10 GAX13625.1 - 1.5e-09 38.0 1.2 1.9e-09 37.7 1.2 1.2 1 0 0 1 1 1 1 COPI associated protein DUF5336 PF17270.2 GAX13625.1 - 0.22 11.2 2.7 0.35 10.5 2.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF4282 PF14110.6 GAX13625.1 - 1.1 10.0 5.2 2.9 8.7 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) CDO_I PF05995.12 GAX13626.1 - 6.5e-31 106.9 0.4 9.5e-31 106.4 0.4 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 GAX13626.1 - 0.00023 20.7 0.8 0.0006 19.3 0.8 1.8 1 1 0 1 1 1 1 PCO_ADO DUF4407 PF14362.6 GAX13628.1 - 0.25 10.6 16.2 0.025 13.9 3.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Arm-DNA-bind_4 PF14657.6 GAX13628.1 - 0.89 9.4 2.5 36 4.2 0.2 2.6 2 0 0 2 2 2 0 Arm DNA-binding domain MIT PF04212.18 GAX13628.1 - 1.3 9.1 5.2 12 6.1 0.5 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain FliD_C PF07195.12 GAX13628.1 - 2 7.8 14.8 4.8 6.5 1.9 3.9 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus DUF4404 PF14357.6 GAX13628.1 - 2.8 8.6 13.1 5.4 7.7 1.4 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) SPRY PF00622.28 GAX13629.1 - 1.6e-08 34.7 0.3 0.00066 19.8 0.1 2.8 2 1 0 2 2 2 2 SPRY domain IGPS PF00218.21 GAX13630.1 - 2.1e-66 223.7 0.3 8.1e-66 221.8 0.1 2.0 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 GAX13630.1 - 1.2e-45 155.6 0.3 2.5e-38 131.8 0.0 2.5 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.19 GAX13630.1 - 0.0095 15.7 0.0 0.58 9.9 0.0 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NPL4 PF05021.15 GAX13631.1 - 3.6e-06 26.6 0.2 0.00013 21.4 0.1 2.7 2 1 0 2 2 2 1 NPL4 family FDF PF09532.10 GAX13631.1 - 0.17 12.8 1.1 34 5.4 0.0 2.8 3 0 0 3 3 3 0 FDF domain PHD PF00628.29 GAX13632.1 - 0.0084 16.0 6.2 0.0084 16.0 6.2 1.9 2 0 0 2 2 2 1 PHD-finger 2OG-FeII_Oxy_3 PF13640.6 GAX13633.1 - 1.8e-05 25.5 0.0 4.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily K-box PF01486.17 GAX13633.1 - 0.037 14.2 0.4 0.072 13.3 0.4 1.4 1 0 0 1 1 1 0 K-box region KASH_CCD PF14662.6 GAX13633.1 - 0.075 12.8 1.8 0.1 12.4 0.8 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH PLAC8 PF04749.17 GAX13635.1 - 1.8e-13 51.3 9.7 3.9e-13 50.2 9.7 1.6 1 0 0 1 1 1 1 PLAC8 family EMG1 PF03587.14 GAX13636.1 - 2e-66 223.4 0.0 2.6e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase FAD_binding_3 PF01494.19 GAX13637.1 - 0.00016 21.1 1.1 1.2 8.3 0.1 3.5 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 GAX13637.1 - 0.036 13.7 4.2 0.063 12.9 2.6 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 GAX13637.1 - 0.097 11.7 0.0 0.37 9.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 GAX13637.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UQ_con PF00179.26 GAX13638.1 - 7.9e-48 161.7 0.1 8.7e-48 161.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX13638.1 - 0.017 15.4 0.2 0.023 15.0 0.2 1.4 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 GAX13638.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 TPR_2 PF07719.17 GAX13639.1 - 0.0068 16.4 0.1 0.0068 16.4 0.1 2.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX13639.1 - 0.013 15.3 0.1 0.013 15.3 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX13639.1 - 0.024 14.9 0.2 0.024 14.9 0.2 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PAS_9 PF13426.7 GAX13640.1 - 2.1e-05 24.7 0.1 0.00012 22.3 0.0 2.3 2 1 0 2 2 2 1 PAS domain bZIP_1 PF00170.21 GAX13640.1 - 0.00049 20.1 6.2 0.00049 20.1 6.2 2.6 2 0 0 2 2 2 1 bZIP transcription factor PAS PF00989.25 GAX13640.1 - 0.016 15.2 0.3 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 PAS fold bZIP_2 PF07716.15 GAX13640.1 - 0.11 12.7 8.3 0.36 10.9 8.3 2.0 1 0 0 1 1 1 0 Basic region leucine zipper Rrf2 PF02082.20 GAX13640.1 - 0.11 12.9 0.2 9.5 6.7 0.0 2.9 2 0 0 2 2 2 0 Transcriptional regulator bZIP_2 PF07716.15 GAX13641.1 - 2.4e-08 33.9 4.3 2.4e-08 33.9 4.3 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX13641.1 - 1.8e-05 24.8 1.2 1.8e-05 24.8 1.2 2.2 2 0 0 2 2 2 1 bZIP transcription factor Ino80_Iec3 PF14612.6 GAX13641.1 - 0.011 16.4 1.0 0.019 15.7 1.0 1.4 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling GlnD_UR_UTase PF08335.11 GAX13641.1 - 0.063 13.4 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase FIN1 PF17300.2 GAX13641.1 - 0.13 11.7 4.0 0.12 11.8 0.6 2.1 2 0 0 2 2 2 0 Filaments in between nuclei protein-1 CRT-like PF08627.10 GAX13642.1 - 9.3e-75 251.6 13.5 1.5e-37 129.3 2.7 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 GAX13642.1 - 0.00068 19.2 4.9 0.00068 19.2 4.9 2.1 2 0 0 2 2 2 1 Solute carrier family 35 DUF373 PF04123.13 GAX13642.1 - 0.016 14.7 3.6 1.4 8.3 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF373) DUF4366 PF14283.6 GAX13642.1 - 0.086 12.9 0.1 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) EamA PF00892.20 GAX13642.1 - 0.24 11.6 35.5 0.049 13.8 8.9 3.2 3 0 0 3 3 3 0 EamA-like transporter family Polysacc_deac_1 PF01522.21 GAX13643.1 - 5.1e-08 32.8 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase HSP70 PF00012.20 GAX13644.1 - 4.2e-08 31.8 0.0 0.00022 19.6 0.0 3.0 3 0 0 3 3 3 2 Hsp70 protein Ppx-GppA PF02541.16 GAX13644.1 - 0.014 14.9 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Actin PF00022.19 GAX13644.1 - 0.12 10.9 0.0 0.21 10.1 0.0 1.4 1 0 0 1 1 1 0 Actin zf-HIT PF04438.16 GAX13645.1 - 6.5e-05 22.7 14.2 0.0001 22.1 14.2 1.3 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 GAX13645.1 - 0.091 10.6 6.1 0.12 10.2 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 VATC PF18716.1 GAX13645.1 - 0.34 10.8 10.0 0.63 9.9 10.0 1.4 1 0 0 1 1 1 0 Vms1-associating treble clef domain PMI_typeI PF01238.21 GAX13646.1 - 0.056 12.6 0.1 0.068 12.3 0.1 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I Peptidase_M18 PF02127.15 GAX13646.1 - 0.068 11.9 0.1 0.084 11.7 0.1 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) Herpes_UL3 PF03369.13 GAX13646.1 - 0.32 11.5 1.9 0.41 11.2 1.6 1.3 1 1 0 1 1 1 0 Herpesvirus UL3 protein Mucin PF01456.17 GAX13646.1 - 0.34 10.9 16.7 0.46 10.5 16.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.8 GAX13646.1 - 0.57 9.3 6.7 0.58 9.3 6.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MMS19_N PF14500.6 GAX13647.1 - 0.026 14.1 8.2 0.11 12.1 1.2 2.9 2 2 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II GRIP PF01465.20 GAX13647.1 - 0.061 13.2 0.9 17 5.4 0.1 3.7 3 0 0 3 3 3 0 GRIP domain NusB PF01029.18 GAX13647.1 - 0.11 12.8 0.7 0.4 10.9 0.0 2.2 3 0 0 3 3 3 0 NusB family V-ATPase_H_C PF11698.8 GAX13647.1 - 2 8.5 6.4 3.2 7.9 0.4 3.9 2 2 2 4 4 4 0 V-ATPase subunit H Arm PF00514.23 GAX13647.1 - 2.6 8.2 5.8 8.8 6.5 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HCO3_cotransp PF00955.21 GAX13648.1 - 3.2e-90 303.4 12.6 5.3e-53 180.6 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family Dioxygenase_C PF00775.21 GAX13649.1 - 9.9e-11 41.4 0.1 2.2e-08 33.8 0.1 2.5 1 1 0 1 1 1 1 Dioxygenase Tyr-DNA_phospho PF06087.12 GAX13650.1 - 2.9e-25 89.0 0.1 9.5e-25 87.4 0.0 1.7 2 1 0 2 2 2 1 Tyrosyl-DNA phosphodiesterase SUIM_assoc PF16619.5 GAX13650.1 - 0.093 12.8 5.0 0.1 12.6 2.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dicty_REP PF05086.12 GAX13650.1 - 0.23 9.4 1.9 0.39 8.6 1.9 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PfkB PF00294.24 GAX13651.1 - 7.4e-27 94.4 0.1 3e-22 79.3 0.0 2.4 3 0 0 3 3 3 2 pfkB family carbohydrate kinase AP_endonuc_2 PF01261.24 GAX13651.1 - 1.3e-17 63.9 0.0 3.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PPR_2 PF13041.6 GAX13652.1 - 3.5e-08 33.5 1.1 0.0011 19.1 0.0 4.7 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 GAX13652.1 - 4.2e-07 29.9 0.0 0.0084 16.2 0.0 3.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX13652.1 - 1.1e-05 25.0 2.0 0.043 13.2 0.0 3.6 2 2 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAX13652.1 - 0.46 10.2 9.7 11 5.8 0.1 4.5 5 0 0 5 5 5 0 PPR repeat PPR PF01535.20 GAX13652.1 - 1 9.8 4.1 43 4.7 0.0 4.9 6 0 0 6 6 6 0 PPR repeat SET PF00856.28 GAX13653.1 - 1.4e-12 48.3 0.0 2.3e-12 47.6 0.0 1.3 1 1 0 1 1 1 1 SET domain AAA PF00004.29 GAX13654.1 - 6e-45 152.9 0.5 2.3e-44 151.0 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX13654.1 - 9.6e-09 35.4 0.1 3.2e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 GAX13654.1 - 1e-08 35.0 0.1 5.8e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 GAX13654.1 - 2.1e-08 34.5 0.1 8.9e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 GAX13654.1 - 1.2e-07 31.4 0.1 2.9e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX13654.1 - 9.1e-07 29.4 0.0 0.00037 20.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 GAX13654.1 - 4e-05 22.9 0.0 9.3e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAX13654.1 - 0.00011 22.5 2.4 0.011 16.0 0.6 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX13654.1 - 0.00016 22.2 0.6 0.00079 20.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 GAX13654.1 - 0.00017 21.2 0.0 0.00062 19.3 0.0 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 GAX13654.1 - 0.00018 21.3 0.0 0.0006 19.6 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAX13654.1 - 0.00028 20.2 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain NTPase_1 PF03266.15 GAX13654.1 - 0.0012 18.8 0.3 0.088 12.7 0.0 3.0 3 0 0 3 3 3 1 NTPase Mg_chelatase PF01078.21 GAX13654.1 - 0.002 17.5 0.1 0.0046 16.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAX13654.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAX13654.1 - 0.0023 18.3 0.0 0.0057 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 GAX13654.1 - 0.0047 17.2 0.2 0.016 15.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 GAX13654.1 - 0.0056 16.4 0.1 0.022 14.5 0.1 2.0 2 1 0 2 2 2 1 AAA domain DUF3450 PF11932.8 GAX13654.1 - 0.0062 15.9 0.8 0.012 15.0 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) IstB_IS21 PF01695.17 GAX13654.1 - 0.0066 16.2 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 GAX13654.1 - 0.0067 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 GAX13654.1 - 0.0097 15.0 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 GAX13654.1 - 0.011 15.9 0.2 0.075 13.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 GAX13654.1 - 0.016 14.6 0.5 0.21 10.9 0.0 2.4 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 GAX13654.1 - 0.02 14.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 GAX13654.1 - 0.029 14.8 0.1 0.076 13.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 GAX13654.1 - 0.055 13.3 0.3 0.18 11.6 0.0 2.0 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAX13654.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAX13654.1 - 0.057 13.2 1.3 0.3 10.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 GAX13654.1 - 0.097 12.6 0.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Torsin PF06309.11 GAX13654.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.6 GAX13654.1 - 0.19 11.3 1.5 0.3 10.6 0.1 2.0 2 1 1 3 3 2 0 AAA domain Guanylate_kin PF00625.21 GAX13654.1 - 0.59 9.8 3.4 2.1 8.0 0.0 3.0 2 1 1 4 4 4 0 Guanylate kinase CENP-Q PF13094.6 GAX13654.1 - 1.9 8.7 7.2 20 5.4 5.5 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit OCD_Mu_crystall PF02423.15 GAX13655.1 - 8.9e-37 126.7 0.1 2.7e-36 125.1 0.1 1.6 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 GAX13655.1 - 8.7e-06 25.9 1.2 0.00012 22.2 1.2 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Brix PF04427.18 GAX13656.1 - 2.4e-30 106.1 0.0 3.4e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain RNB PF00773.19 GAX13658.1 - 2.2e-89 300.0 0.0 3.7e-89 299.3 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAX13658.1 - 0.00023 21.1 0.3 0.0012 18.9 0.1 2.4 2 1 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) OB_RNB PF08206.11 GAX13658.1 - 0.0035 17.0 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain STPPase_N PF16891.5 GAX13658.1 - 0.0049 17.3 0.4 0.014 15.9 0.0 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Dis3l2_C_term PF17877.1 GAX13658.1 - 0.12 12.7 0.0 0.44 10.9 0.0 2.0 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Peptidase_S8 PF00082.22 GAX13659.1 - 1.3e-45 156.0 0.3 2e-45 155.3 0.3 1.2 1 0 0 1 1 1 1 Subtilase family ShK PF01549.24 GAX13659.1 - 0.0009 19.7 9.6 0.016 15.8 1.7 2.7 2 0 0 2 2 2 2 ShK domain-like Actin PF00022.19 GAX13660.1 - 1.7e-67 227.8 0.0 2.6e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 Actin CDC45 PF02724.14 GAX13660.1 - 0.63 8.3 4.8 0.87 7.8 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Arm PF00514.23 GAX13661.1 - 4.4e-15 55.1 22.7 3.2e-06 27.0 0.3 7.9 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 GAX13661.1 - 0.0022 18.0 3.1 0.54 10.3 0.0 3.5 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain IGPD PF00475.18 GAX13661.1 - 0.011 16.1 0.9 0.027 14.8 0.2 2.0 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase OCRL_clath_bd PF16726.5 GAX13661.1 - 0.04 14.1 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Inositol polyphosphate 5-phosphatase clathrin binding domain DUF3361 PF11841.8 GAX13661.1 - 1.1 9.2 8.7 0.98 9.4 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) MA3 PF02847.17 GAX13663.1 - 4.9e-23 81.3 0.1 1e-22 80.3 0.1 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 GAX13663.1 - 1.3e-15 57.6 0.0 6e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain SPX PF03105.19 GAX13663.1 - 0.095 12.6 26.1 0.2 11.6 23.7 2.1 2 0 0 2 2 2 0 SPX domain Hid1 PF12722.7 GAX13663.1 - 8.6 4.4 15.5 25 2.8 15.5 1.7 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank_2 PF12796.7 GAX13665.1 - 3.7e-10 40.2 0.0 1.8 9.2 0.0 6.2 3 3 1 5 5 5 3 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 GAX13665.1 - 1.2e-08 34.6 8.8 2.1e-08 33.9 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX13665.1 - 3.6e-08 33.1 10.0 6.8e-08 32.2 10.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank PF00023.30 GAX13665.1 - 3.2e-07 30.5 4.5 5.4 7.7 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 GAX13665.1 - 3.7e-07 30.3 0.2 0.32 11.4 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX13665.1 - 3.8e-07 29.9 0.5 9.9 7.1 0.0 6.7 5 0 0 5 5 5 1 Ankyrin repeat zf-RING_2 PF13639.6 GAX13665.1 - 0.008 16.5 9.8 0.017 15.5 9.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAX13665.1 - 0.19 11.7 7.9 0.39 10.7 7.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RMI1_N PF08585.12 GAX13666.1 - 4.9e-18 65.7 1.7 2.1e-17 63.6 0.1 2.5 2 1 0 2 2 2 1 RecQ mediated genome instability protein DUF1493 PF07377.12 GAX13666.1 - 0.14 12.6 0.1 0.28 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Hamartin PF04388.12 GAX13666.1 - 0.3 9.7 6.2 0.41 9.3 6.2 1.2 1 0 0 1 1 1 0 Hamartin protein B12D PF06522.11 GAX13667.1 - 0.00012 21.8 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GCV_T PF01571.21 GAX13668.1 - 1.7e-08 34.2 0.0 2.6e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain Mito_carr PF00153.27 GAX13669.1 - 3.3e-34 116.7 2.5 3.6e-14 52.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.11 GAX13670.1 - 1.1e-10 41.1 0.1 2e-10 40.3 0.0 1.4 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PspA_IM30 PF04012.12 GAX13671.1 - 8.3e-45 153.1 26.0 8.3e-45 153.1 26.0 1.4 2 0 0 2 2 2 1 PspA/IM30 family Spc7 PF08317.11 GAX13671.1 - 0.0054 15.7 28.5 0.28 10.0 3.1 2.9 1 1 1 2 2 2 2 Spc7 kinetochore protein NPV_P10 PF05531.12 GAX13671.1 - 0.1 13.1 10.1 10 6.7 0.0 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 GAX13671.1 - 0.17 12.0 14.4 0.78 9.9 7.3 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Pox_F11 PF04943.12 GAX13671.1 - 0.72 8.9 9.7 0.54 9.3 8.5 1.3 1 1 0 1 1 1 0 Poxvirus F11 protein PYC_OADA PF02436.18 GAX13671.1 - 1.8 8.3 5.9 0.35 10.6 0.6 2.3 1 1 0 2 2 2 0 Conserved carboxylase domain UPF0242 PF06785.11 GAX13671.1 - 2.2 8.3 19.7 0.067 13.3 10.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cob_adeno_trans PF01923.18 GAX13671.1 - 3.4 7.8 11.6 20 5.3 5.7 3.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Lebercilin PF15619.6 GAX13671.1 - 6.9 6.3 24.7 0.2 11.3 15.8 2.4 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Glyco_hydro_4C PF11975.8 GAX13672.1 - 0.052 13.6 0.1 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Radical_SAM PF04055.21 GAX13673.1 - 4e-29 102.1 0.0 1.5e-28 100.3 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 GAX13673.1 - 4.6e-27 93.9 0.2 1.1e-26 92.7 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 GAX13673.1 - 1.8e-07 31.1 0.0 7.4e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 TRAM domain DUF2326 PF10088.9 GAX13673.1 - 0.08 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) GlnD_UR_UTase PF08335.11 GAX13674.1 - 0.01 15.9 1.1 0.016 15.3 1.1 1.4 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase DUF4731 PF15875.5 GAX13674.1 - 0.18 12.0 0.8 1.6 8.9 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4731) MutS_V PF00488.21 GAX13675.1 - 1.8e-77 259.7 0.7 4.2e-77 258.4 0.4 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 GAX13675.1 - 7.2e-19 68.8 1.0 1.7e-18 67.6 1.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAX13675.1 - 0.00011 22.5 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 GAX13675.1 - 0.016 14.8 0.0 0.047 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX13675.1 - 0.019 15.3 0.0 0.065 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX13675.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX13675.1 - 0.83 10.1 0.0 0.83 10.1 0.0 2.3 2 1 1 3 3 3 0 AAA domain Guanylate_cyc PF00211.20 GAX13676.1 - 6e-43 146.6 0.0 1.1e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX13676.1 - 7.6e-33 114.2 2.4 1.7e-32 113.1 2.4 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 GAX13676.1 - 0.0056 16.6 0.0 0.028 14.4 0.0 2.1 1 1 0 1 1 1 1 CHASE domain DUF1357 PF07094.11 GAX13676.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) RecX PF02631.16 GAX13676.1 - 0.033 14.6 1.5 0.083 13.3 1.5 1.6 1 0 0 1 1 1 0 RecX family PAS_10 PF13596.6 GAX13676.1 - 0.21 12.2 1.3 2.1 9.0 0.1 3.1 3 0 0 3 3 3 0 PAS domain DUF3149 PF11346.8 GAX13677.1 - 0.061 12.9 1.4 0.3 10.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) MORN PF02493.20 GAX13678.1 - 4.4e-26 89.2 82.9 6.5e-05 22.6 0.9 12.3 12 0 0 12 12 12 11 MORN repeat Glycos_transf_2 PF00535.26 GAX13679.1 - 1.9e-16 60.3 0.0 2.3e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX13679.1 - 2.9e-05 24.1 0.0 3.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAX13679.1 - 3.5e-05 23.3 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 OCRE PF17780.1 GAX13680.1 - 1.4e-06 28.2 3.6 2.1e-06 27.6 3.6 1.3 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 GAX13680.1 - 3.9e-06 26.7 1.2 9.3e-06 25.4 1.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAX13680.1 - 0.00028 20.9 0.5 0.00077 19.5 0.5 1.9 1 0 0 1 1 1 1 G-patch domain zf-C2H2_4 PF13894.6 GAX13680.1 - 0.005 17.6 0.2 0.012 16.4 0.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAX13680.1 - 0.036 14.4 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAX13680.1 - 0.045 14.0 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 GAX13680.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 GAX13680.1 - 1.1 9.1 5.5 0.28 11.1 1.1 2.4 2 1 0 2 2 2 0 Rad50 zinc hook motif DUF285 PF03382.14 GAX13681.1 - 3.1e-124 407.8 80.2 4.3e-34 116.9 17.3 4.2 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 Pkinase PF00069.25 GAX13682.1 - 4e-10 39.5 0.0 3e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain F-box-like PF12937.7 GAX13682.1 - 5.8e-05 22.9 0.3 0.00015 21.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like Pkinase_Tyr PF07714.17 GAX13682.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase F-box PF00646.33 GAX13682.1 - 0.022 14.6 0.0 0.079 12.9 0.0 1.9 1 0 0 1 1 1 0 F-box domain zf-C2H2_4 PF13894.6 GAX13682.1 - 0.45 11.5 5.5 14 6.8 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger LRR_8 PF13855.6 GAX13684.1 - 3.1e-24 84.5 32.8 1.6e-08 34.2 2.6 5.5 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX13684.1 - 6.9e-13 48.6 36.3 0.00013 22.3 1.9 6.5 2 1 7 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX13684.1 - 0.25 12.0 29.1 5.2 8.0 0.2 9.4 10 0 0 10 10 10 0 Leucine Rich Repeat HA PF03457.14 GAX13686.1 - 4.9e-05 23.6 0.0 0.00024 21.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain FYRN PF05964.14 GAX13686.1 - 0.16 11.8 0.2 0.33 10.8 0.2 1.5 1 0 0 1 1 1 0 F/Y-rich N-terminus ATP-gua_Ptrans PF00217.19 GAX13687.1 - 4.4e-44 150.5 0.0 6.2e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 GAX13687.1 - 1.7e-20 73.1 0.0 5e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain YccJ PF13993.6 GAX13688.1 - 0.059 13.7 1.7 0.13 12.6 1.6 1.6 1 1 0 1 1 1 0 YccJ-like protein Ribosomal_L39 PF00832.20 GAX13690.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L39 protein Voltage_CLC PF00654.20 GAX13691.1 - 8.6e-93 311.4 15.2 8.6e-93 311.4 15.2 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAX13691.1 - 9.3e-08 32.4 0.0 5.4e-06 26.8 0.0 2.9 3 0 0 3 3 3 1 CBS domain PFK PF00365.20 GAX13692.1 - 9.4e-58 195.8 0.4 1.2e-57 195.4 0.4 1.1 1 0 0 1 1 1 1 Phosphofructokinase LSDAT_euk PF18139.1 GAX13692.1 - 0.05 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 SLOG in TRPM Smr PF01713.21 GAX13692.1 - 0.12 12.8 0.4 14 6.2 0.1 2.5 2 0 0 2 2 2 0 Smr domain DAGK_cat PF00781.24 GAX13692.1 - 0.13 11.9 0.1 0.86 9.2 0.0 2.4 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Gly_transf_sug PF04488.15 GAX13693.1 - 3.1e-09 37.3 0.0 1.6e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX13693.1 - 2.8e-06 26.9 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein RCC1 PF00415.18 GAX13694.1 - 2.6e-28 98.4 10.9 3.3e-09 37.2 0.0 6.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX13694.1 - 5.4e-20 70.7 21.3 7.4e-05 22.4 0.3 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Amino_oxidase PF01593.24 GAX13694.1 - 6.2e-20 71.9 0.0 8e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAX13694.1 - 1.7e-08 34.4 1.6 4.3e-07 29.8 1.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX13694.1 - 9.6e-08 32.1 0.2 2.3e-07 30.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAX13694.1 - 1e-07 31.0 3.8 5.6e-05 22.0 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 GAX13694.1 - 3.1e-07 29.9 0.3 0.02 14.2 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX13694.1 - 2.4e-06 27.6 0.9 0.029 14.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 GAX13694.1 - 0.00076 18.8 0.4 0.0034 16.7 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 GAX13694.1 - 0.00092 18.6 0.1 0.41 9.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX13694.1 - 0.0011 18.1 0.6 0.029 13.4 0.3 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 GAX13694.1 - 0.0012 19.4 0.5 0.046 14.3 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAX13694.1 - 0.014 14.5 0.1 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.19 GAX13694.1 - 0.037 13.4 0.5 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.19 GAX13694.1 - 0.057 12.6 0.1 1 8.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain DUF1188 PF06690.11 GAX13694.1 - 0.059 12.9 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FAD_oxidored PF12831.7 GAX13694.1 - 0.064 12.6 0.8 0.1 11.9 0.3 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX13694.1 - 0.11 11.5 2.7 0.28 10.2 1.1 2.2 3 0 0 3 3 3 0 FAD binding domain Gln-synt_C-ter PF18318.1 GAX13695.1 - 2.7e-25 88.5 0.0 5.4e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 GAX13695.1 - 6.3e-18 64.9 0.0 2.4e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain GSIII_N PF12437.8 GAX13695.1 - 2.6e-15 56.5 0.6 8.6e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal SpoU_methylase PF00588.19 GAX13696.1 - 8.4e-26 90.8 0.0 1.2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAX13696.1 - 2.8e-09 37.1 0.0 1.4e-06 28.5 0.0 2.5 2 0 0 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding His_Phos_1 PF00300.22 GAX13697.1 - 1.4e-19 70.5 0.1 4.1e-19 69.1 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SPARC_Ca_bdg PF10591.9 GAX13697.1 - 0.043 14.1 0.5 0.25 11.7 0.1 2.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region SNF5 PF04855.12 GAX13698.1 - 1.1e-09 38.5 0.9 2.3e-08 34.2 0.1 2.1 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 Ependymin PF00811.18 GAX13698.1 - 0.058 13.6 0.1 4.2 7.6 0.1 2.2 1 1 1 2 2 2 0 Ependymin Lung_7-TM_R PF06814.13 GAX13700.1 - 0.00015 21.1 9.0 0.0038 16.5 9.0 2.2 1 1 0 1 1 1 1 Lung seven transmembrane receptor TFR_dimer PF04253.15 GAX13700.1 - 0.006 16.7 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain DUF2569 PF10754.9 GAX13700.1 - 5.9 7.3 10.4 0.18 12.2 0.3 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2569) Lung_7-TM_R PF06814.13 GAX13701.1 - 4.6e-08 32.6 15.5 1.7e-06 27.5 15.5 2.2 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF1772 PF08592.11 GAX13701.1 - 0.5 10.7 0.0 0.5 10.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) TssN PF17555.2 GAX13701.1 - 4.6 6.5 14.1 0.77 9.1 7.9 2.3 1 1 1 2 2 2 0 Type VI secretion system, TssN zf-LITAF-like PF10601.9 GAX13701.1 - 6.8 7.0 7.8 5.2 7.4 1.4 2.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DSBA PF01323.20 GAX13702.1 - 2.1e-15 57.0 0.2 2.3e-15 56.9 0.2 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 GAX13702.1 - 4.7e-06 26.4 0.1 6.7e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX13703.1 - 5.8e-23 81.0 0.0 1.3e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Transglut_core PF01841.19 GAX13703.1 - 2.7e-09 37.4 0.1 6.9e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Thioredoxin PF00085.20 GAX13703.1 - 0.00021 21.2 0.0 0.0027 17.7 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Rad4 PF03835.15 GAX13703.1 - 0.00032 20.4 0.0 0.00077 19.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PAW PF04721.17 GAX13703.1 - 0.0064 16.3 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Thioredoxin_2 PF13098.6 GAX13703.1 - 0.011 16.2 0.0 0.076 13.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain Zn_Tnp_IS1595 PF12760.7 GAX13703.1 - 0.15 12.1 5.1 0.29 11.1 4.5 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF2664 PF10867.8 GAX13703.1 - 1.7 9.1 5.9 0.45 11.0 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) CAF1A PF12253.8 GAX13704.1 - 0.89 9.8 20.7 10 6.4 0.0 3.4 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A TFIIA PF03153.13 GAX13704.1 - 5.1 7.0 10.7 6.4 6.6 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 GAX13705.1 - 0.0011 18.4 13.8 0.0011 18.4 13.8 1.1 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 GAX13705.1 - 0.0021 18.3 11.7 0.0022 18.2 11.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein PTPRCAP PF15713.5 GAX13705.1 - 0.0028 18.0 12.9 0.0032 17.8 12.9 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated GAGA_bind PF06217.12 GAX13705.1 - 0.0043 17.4 9.2 0.0051 17.1 9.2 1.0 1 0 0 1 1 1 1 GAGA binding protein-like family EPL1 PF10513.9 GAX13705.1 - 0.0062 16.9 11.4 0.0084 16.5 11.4 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like CDC45 PF02724.14 GAX13705.1 - 0.0073 14.7 13.3 0.0075 14.6 13.3 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 GAX13705.1 - 0.01 15.2 14.7 0.013 15.0 14.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) OATP PF03137.20 GAX13705.1 - 0.013 13.9 1.5 0.016 13.5 1.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SprA-related PF12118.8 GAX13705.1 - 0.05 12.8 10.6 0.053 12.7 10.6 1.1 1 0 0 1 1 1 0 SprA-related family CobT PF06213.12 GAX13705.1 - 0.052 12.9 17.2 0.065 12.6 17.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YqfQ PF14181.6 GAX13705.1 - 0.081 13.1 10.7 0.11 12.7 10.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein Nop14 PF04147.12 GAX13705.1 - 0.15 10.2 17.0 0.17 10.1 17.0 1.0 1 0 0 1 1 1 0 Nop14-like family NARP1 PF12569.8 GAX13705.1 - 0.21 10.4 13.0 0.25 10.2 13.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CLN3 PF02487.17 GAX13705.1 - 0.44 9.5 2.8 0.58 9.1 2.8 1.2 1 0 0 1 1 1 0 CLN3 protein RRN3 PF05327.11 GAX13705.1 - 0.61 8.6 10.6 0.65 8.5 10.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 GAX13705.1 - 0.63 8.8 11.0 0.77 8.4 11.0 1.2 1 0 0 1 1 1 0 Presenilin CSG2 PF16965.5 GAX13705.1 - 0.76 8.7 4.3 0.92 8.4 4.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4407 PF14362.6 GAX13705.1 - 0.86 8.9 5.7 0.96 8.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spt5_N PF11942.8 GAX13705.1 - 0.86 10.6 19.0 1.6 9.8 19.0 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SLC12 PF03522.15 GAX13705.1 - 1 8.3 11.4 1.2 8.1 11.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 O-antigen_lig PF13425.6 GAX13705.1 - 1.5 7.5 8.7 1.8 7.3 8.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Zip PF02535.22 GAX13705.1 - 2 7.6 5.8 2.5 7.2 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ORC3_N PF07034.11 GAX13705.1 - 2.6 7.1 6.6 3.1 6.8 6.6 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus GREB1 PF15782.5 GAX13705.1 - 3.5 4.6 9.9 3.7 4.5 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 GAX13705.1 - 3.8 7.5 8.2 4.5 7.3 8.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.16 GAX13705.1 - 3.9 6.9 10.7 5.1 6.6 10.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 ALMT PF11744.8 GAX13705.1 - 6.4 5.5 8.9 7.1 5.3 8.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0239 PF06783.11 GAX13705.1 - 8.5 6.6 14.5 64 3.8 14.5 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) WD40 PF00400.32 GAX13710.1 - 1.1e-07 32.4 12.0 0.21 12.5 0.1 7.6 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX13710.1 - 0.0018 18.5 0.0 1.2 9.5 0.0 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 GAX13710.1 - 0.034 13.5 0.1 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal CoA_trans PF01144.23 GAX13711.1 - 1.1e-91 306.1 2.9 4.4e-52 176.6 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase GDP_Man_Dehyd PF16363.5 GAX13714.1 - 1.9e-152 507.4 0.0 2.2e-152 507.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX13714.1 - 7.1e-73 245.0 0.1 9.3e-73 244.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX13714.1 - 0.00021 20.5 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAX13714.1 - 0.00091 18.4 0.0 0.0021 17.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GAX13714.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family Sedlin_N PF04628.13 GAX13716.1 - 6.8e-24 84.5 0.0 9.1e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAX13716.1 - 2e-08 34.3 0.1 4.9e-08 33.0 0.1 1.6 2 0 0 2 2 2 1 Sybindin-like family DUF272 PF03312.15 GAX13716.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF272) DUF728 PF05304.12 GAX13717.1 - 3.4 7.5 7.5 3.9 7.3 3.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF728) Cir_N PF10197.9 GAX13718.1 - 1.2e-10 41.4 12.1 1.2e-10 41.4 12.1 3.2 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 GAX13718.1 - 0.035 13.9 0.2 0.091 12.6 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle SR-25 PF10500.9 GAX13718.1 - 2.1 7.9 35.3 0.078 12.6 25.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_12 PF13424.6 GAX13719.1 - 1.5e-19 70.0 8.0 4e-08 33.4 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 GAX13719.1 - 4e-18 65.5 0.0 7.5e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 GAX13719.1 - 1.1e-09 37.8 3.6 0.0048 16.7 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX13719.1 - 1.9e-08 33.7 2.6 0.14 12.3 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX13719.1 - 6.1e-06 26.0 9.0 0.13 12.6 0.2 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX13719.1 - 0.0013 18.4 4.0 0.28 11.1 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX13719.1 - 0.004 17.2 9.8 7.3 7.0 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX13719.1 - 0.0084 15.8 2.6 0.51 10.0 0.3 2.4 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) SMBP PF16785.5 GAX13719.1 - 0.042 14.1 1.7 0.43 10.8 1.8 2.5 2 0 0 2 2 2 0 Small metal-binding protein TPR_16 PF13432.6 GAX13719.1 - 0.15 12.7 2.7 31 5.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RrnaAD PF00398.20 GAX13720.1 - 9.6e-42 142.9 0.0 1.3e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAX13720.1 - 0.00019 22.1 0.0 0.00041 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX13720.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 GAX13720.1 - 0.0036 16.9 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 GAX13720.1 - 0.0042 17.7 0.0 0.06 14.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX13720.1 - 0.009 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX13720.1 - 0.01 16.5 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1016_N PF17761.1 GAX13720.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 DUF1016 N-terminal domain LPD23 PF18838.1 GAX13720.1 - 0.42 10.4 3.7 0.8 9.5 3.7 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 TFIIS_M PF07500.14 GAX13721.1 - 8.9e-21 74.5 1.0 8.9e-21 74.5 1.0 2.2 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 GAX13721.1 - 2.1e-17 62.7 4.6 2.1e-17 62.7 4.6 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 GAX13721.1 - 1.4e-08 34.6 0.7 9e-08 32.0 0.0 2.6 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zf-DNL PF05180.12 GAX13721.1 - 0.033 14.1 0.9 0.033 14.1 0.9 1.9 2 0 0 2 2 2 0 DNL zinc finger Aldedh PF00171.22 GAX13721.1 - 0.084 11.4 3.9 0.12 10.9 3.9 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family CSN5_C PF18323.1 GAX13721.1 - 3.6 8.6 6.6 14 6.7 0.7 3.0 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Lar_restr_allev PF14354.6 GAX13721.1 - 4.3 7.8 7.0 3.2 8.2 0.3 3.4 3 1 0 3 3 3 0 Restriction alleviation protein Lar gp37_C PF12604.8 GAX13723.1 - 0.022 14.5 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Tail fibre protein gp37 C terminal Sec16 PF12932.7 GAX13723.1 - 0.036 14.6 3.2 0.063 13.9 1.6 2.2 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region PixA PF12306.8 GAX13723.1 - 0.088 13.0 0.8 11 6.2 0.3 2.3 2 0 0 2 2 2 0 Inclusion body protein CRT10 PF08728.10 GAX13723.1 - 0.69 8.0 9.2 1.2 7.3 9.2 1.3 1 0 0 1 1 1 0 CRT10 2OG-FeII_Oxy_2 PF13532.6 GAX13725.1 - 2e-31 109.7 0.3 3.6e-31 108.9 0.3 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0020 PF01170.18 GAX13725.1 - 6.2e-28 97.8 0.0 3.3e-27 95.4 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 GAX13725.1 - 3.7e-10 39.8 0.0 8e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX13725.1 - 1.5e-08 35.3 0.1 4.6e-08 33.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 GAX13725.1 - 2.9e-07 30.2 0.0 6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 GAX13725.1 - 1.1e-06 28.2 0.0 2.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 GAX13725.1 - 5e-06 27.1 0.0 1.3e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX13725.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family THUMP PF02926.17 GAX13725.1 - 0.00015 21.9 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 THUMP domain N6_N4_Mtase PF01555.18 GAX13725.1 - 0.0011 18.7 2.5 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 DNA methylase Methyltransf_15 PF09445.10 GAX13725.1 - 0.0056 16.3 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase CMAS PF02353.20 GAX13725.1 - 0.015 14.6 0.1 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase FTO_NTD PF12933.7 GAX13725.1 - 0.022 14.0 0.8 0.038 13.2 0.8 1.3 1 0 0 1 1 1 0 FTO catalytic domain PrmA PF06325.13 GAX13725.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribonuc_red_lgC PF02867.15 GAX13727.1 - 7.6e-187 622.0 0.0 9e-187 621.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAX13727.1 - 5.4e-21 74.4 0.0 1.5e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAX13727.1 - 1.6e-16 60.6 0.0 4.9e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Ion_trans_2 PF07885.16 GAX13728.1 - 1.8e-26 91.9 26.6 1.4e-13 50.6 13.4 2.2 2 0 0 2 2 2 2 Ion channel EF-hand_1 PF00036.32 GAX13728.1 - 6.3e-10 37.9 1.4 2.3e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAX13728.1 - 9.1e-10 38.9 6.3 9.6e-06 26.0 2.0 2.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 GAX13728.1 - 1.6e-09 36.9 1.3 0.0015 17.9 0.1 2.5 2 0 0 2 2 2 2 EF hand Ion_trans PF00520.31 GAX13728.1 - 2.6e-08 33.4 1.2 3.6e-05 23.1 0.0 2.5 2 1 0 2 2 2 2 Ion transport protein EF-hand_6 PF13405.6 GAX13728.1 - 4e-08 32.5 0.3 7.4e-05 22.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAX13728.1 - 0.00024 20.9 3.3 0.089 12.7 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair Lig_chan PF00060.26 GAX13728.1 - 0.034 14.0 4.3 0.44 10.4 4.3 2.4 1 1 0 1 1 1 0 Ligand-gated ion channel IRK PF01007.20 GAX13728.1 - 1.5 8.6 12.0 1.9 8.3 3.0 3.0 3 1 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Sec63 PF02889.16 GAX13729.1 - 1.7e-87 292.8 0.8 3.5e-64 216.5 0.7 3.3 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 GAX13729.1 - 9e-49 165.6 0.0 3.9e-26 91.9 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 GAX13729.1 - 3.8e-21 75.8 0.0 5.3e-12 46.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX13729.1 - 2.5e-15 56.8 0.0 4.8e-07 30.1 0.0 3.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_19 PF13245.6 GAX13729.1 - 5.7e-07 30.0 0.1 0.032 14.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX13729.1 - 2.7e-06 27.7 1.0 0.15 12.4 0.2 4.0 2 2 0 2 2 2 2 AAA domain T2SSE PF00437.20 GAX13729.1 - 0.0092 15.1 0.1 0.65 9.0 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF2075 PF09848.9 GAX13729.1 - 0.011 15.0 0.0 0.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 GAX13729.1 - 0.02 15.3 3.0 1.6 9.2 0.3 4.2 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 GAX13729.1 - 0.02 14.3 0.0 6.9 6.1 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein UvrD-helicase PF00580.21 GAX13729.1 - 0.022 14.3 0.6 2 7.9 0.7 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Zot PF05707.12 GAX13729.1 - 0.042 13.5 0.0 4.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) AhpC-TSA PF00578.21 GAX13730.1 - 4.1e-27 94.5 0.0 5.6e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX13730.1 - 3.2e-16 59.4 0.3 3.9e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 GAX13730.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 SCO1/SenC Exo_endo_phos PF03372.23 GAX13732.1 - 2.9e-09 36.8 0.0 1.4e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5122 PF17164.4 GAX13732.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller T2SSM_b PF10741.9 GAX13732.1 - 0.1 12.4 0.5 12 5.8 0.1 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b PITH PF06201.13 GAX13733.1 - 1.2e-30 106.7 0.0 1.5e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 GAX13733.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.7 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal Adaptin_N PF01602.20 GAX13734.1 - 6e-73 246.2 0.2 9.2e-68 229.1 0.3 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GAX13734.1 - 1.7e-19 70.5 0.6 6.7e-19 68.5 0.2 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAX13734.1 - 2.2e-05 24.7 3.8 0.00055 20.3 0.4 3.6 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 GAX13734.1 - 3.8e-05 23.6 12.9 0.033 14.4 0.2 6.9 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 GAX13734.1 - 0.0002 21.8 0.6 0.0012 19.3 0.1 2.8 2 0 0 2 2 2 1 HEAT-like repeat AP3B1_C PF14796.6 GAX13734.1 - 0.0013 19.0 0.2 0.0047 17.2 0.0 2.1 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal DUF1633 PF07794.11 GAX13734.1 - 0.29 9.2 6.4 0.53 8.4 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Apt1 PF10351.9 GAX13734.1 - 1.1 8.0 16.2 1.8 7.3 16.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_L34 PF00468.17 GAX13735.1 - 3.3e-14 52.6 10.4 4.8e-14 52.1 10.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 DUF3584 PF12128.8 GAX13736.1 - 0.009 13.6 4.5 0.012 13.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DnaJ PF00226.31 GAX13736.1 - 0.012 15.7 2.9 0.047 13.8 0.2 2.6 2 0 0 2 2 2 0 DnaJ domain DUF1682 PF07946.14 GAX13736.1 - 0.025 13.8 4.3 0.049 12.8 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAA_32 PF13654.6 GAX13736.1 - 0.032 13.0 2.7 0.048 12.4 2.7 1.2 1 0 0 1 1 1 0 AAA domain DUF2497 PF10691.9 GAX13736.1 - 0.084 13.3 1.8 0.38 11.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) DUF948 PF06103.11 GAX13736.1 - 0.67 10.2 1.7 1.6 9.1 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Hid1 PF12722.7 GAX13736.1 - 1.1 7.2 7.2 1.6 6.7 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3450 PF11932.8 GAX13736.1 - 2.2 7.5 7.8 0.57 9.4 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF3246 PF11596.8 GAX13737.1 - 0.12 11.8 1.1 0.14 11.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) HhH-GPD PF00730.25 GAX13738.1 - 0.00027 21.3 0.0 0.00043 20.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UBA_4 PF14555.6 GAX13739.1 - 2e-14 53.1 0.0 3.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 GAX13739.1 - 5.2e-14 52.2 0.0 1.4e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 GAX13739.1 - 7.6e-12 45.3 0.0 3.2e-11 43.3 0.0 2.0 3 0 0 3 3 3 1 UBX domain UIM PF02809.20 GAX13739.1 - 0.0081 16.0 5.5 0.0081 16.0 5.5 3.1 3 0 0 3 3 3 1 Ubiquitin interaction motif RAP80_UIM PF18282.1 GAX13739.1 - 0.016 15.0 0.5 0.016 15.0 0.5 2.4 2 1 1 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif PBP1_TM PF14812.6 GAX13739.1 - 0.055 13.8 11.4 1.3 9.4 0.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 GAX13739.1 - 0.94 9.7 13.9 3.7 7.8 4.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) E1_dh PF00676.20 GAX13740.1 - 3e-88 295.7 0.0 3.8e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GAX13740.1 - 6.7e-07 29.2 0.1 5.9e-06 26.2 0.1 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 GAX13740.1 - 0.047 12.9 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Chloroa_b-bind PF00504.21 GAX13742.1 - 3.5e-30 105.7 0.0 4.7e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4334 PF14232.6 GAX13742.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) Chloroa_b-bind PF00504.21 GAX13743.1 - 2.8e-32 112.5 0.3 3.9e-32 112.0 0.3 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RNA_pol_Rpb2_6 PF00562.28 GAX13744.1 - 2.3e-112 375.9 0.0 5e-112 374.8 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAX13744.1 - 2.3e-28 99.1 0.0 3.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 GAX13744.1 - 1.6e-27 95.5 0.0 3.6e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 GAX13744.1 - 5.1e-17 61.6 0.0 1.2e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 GAX13744.1 - 5.1e-15 55.6 0.0 3.5e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GAX13744.1 - 1.6e-09 37.7 0.1 5.9e-06 26.0 0.1 2.8 3 0 0 3 3 3 2 RNA polymerase Rpb2, domain 2 Ins_P5_2-kin PF06090.12 GAX13745.1 - 4.1e-37 128.4 0.0 4.9e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C3HC4_3 PF13920.6 GAX13746.1 - 3.1e-07 30.2 8.2 6.1e-07 29.2 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX13746.1 - 0.0002 21.2 9.6 0.00039 20.3 9.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAX13746.1 - 0.0011 18.7 2.0 0.0027 17.4 2.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAX13746.1 - 0.004 17.1 8.5 0.004 17.1 8.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX13746.1 - 0.015 15.7 10.5 0.03 14.7 10.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 GAX13746.1 - 0.089 12.7 9.7 0.19 11.6 9.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAX13746.1 - 0.13 12.5 5.7 0.42 10.8 5.6 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAX13746.1 - 1.9 8.4 10.6 4 7.4 10.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_ab PF00006.25 GAX13748.1 - 4.4e-68 229.1 0.0 6.4e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAX13748.1 - 3.8e-12 46.5 0.4 7.3e-12 45.6 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_tranf_2_4 PF13704.6 GAX13750.1 - 5.7e-07 30.0 3.4 2.1e-06 28.2 3.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX13750.1 - 0.00089 19.0 0.1 0.0014 18.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 MARVEL PF01284.23 GAX13752.1 - 0.0011 19.0 18.1 1.1 9.3 5.5 3.3 1 1 2 3 3 3 2 Membrane-associating domain DUF2069 PF09842.9 GAX13752.1 - 9.4 6.5 10.6 4.5 7.5 1.8 3.2 2 2 0 2 2 2 0 Predicted membrane protein (DUF2069) Ribosomal_L27e PF01777.18 GAX13754.1 - 3.3e-26 91.5 12.6 4.9e-26 90.9 12.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 GAX13754.1 - 2.7e-05 24.0 0.8 2.7e-05 24.0 0.8 2.5 2 1 0 2 2 2 1 KOW motif MAP65_ASE1 PF03999.12 GAX13755.1 - 3.2e-61 207.8 30.8 4.3e-60 204.1 31.5 1.9 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) ApoLp-III PF07464.11 GAX13755.1 - 0.011 15.8 3.0 1.4 9.0 0.8 3.2 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF1818 PF08848.11 GAX13755.1 - 0.052 13.7 6.0 0.15 12.2 3.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) zf-met2 PF12907.7 GAX13756.1 - 1.2e-12 47.7 0.3 2e-12 47.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding zf-C2H2_4 PF13894.6 GAX13756.1 - 0.15 13.0 0.1 0.26 12.2 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2786 PF10979.8 GAX13756.1 - 0.21 11.5 3.7 0.32 10.9 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) HAD_2 PF13419.6 GAX13757.1 - 4.4e-28 98.6 0.0 1.5e-14 54.5 0.0 2.3 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX13757.1 - 8.8e-11 41.7 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX13757.1 - 4e-09 37.1 0.0 9.3e-08 32.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX13757.1 - 0.0061 17.0 0.2 0.06 13.7 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAX13757.1 - 0.053 13.3 0.1 4.3 7.0 0.1 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Glucan_synthase PF02364.15 GAX13758.1 - 5.5e-153 511.1 10.0 1.5e-117 393.9 0.2 3.4 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 GAX13758.1 - 9.5e-20 71.2 3.4 3.6e-19 69.4 3.4 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DHHC PF01529.20 GAX13759.1 - 9.7e-35 119.6 11.3 9.7e-35 119.6 11.3 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Sec15 PF04091.12 GAX13760.1 - 1.8e-15 57.2 0.0 7.2e-15 55.2 0.0 2.0 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Ribosomal_L37 PF08561.10 GAX13761.1 - 2.2e-09 37.9 5.9 3.6e-07 30.7 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 PNRC PF15365.6 GAX13762.1 - 1.4e-06 27.9 3.3 1.4e-06 27.9 3.3 3.8 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif CDC45 PF02724.14 GAX13762.1 - 8.3 4.6 9.9 9.9 4.3 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein MIP PF00230.20 GAX13763.1 - 1.2e-18 67.7 7.2 3.4e-17 62.9 6.9 2.0 1 1 1 2 2 2 2 Major intrinsic protein DUF2970 PF11174.8 GAX13763.1 - 0.12 12.3 0.5 0.74 9.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2970) Peptidase_M50 PF02163.22 GAX13766.1 - 5e-53 179.9 0.2 7.2e-53 179.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 GAX13766.1 - 0.00016 21.4 0.2 0.00047 19.9 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX13766.1 - 0.0003 21.1 0.0 0.00086 19.6 0.0 1.8 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX13766.1 - 0.0014 19.0 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain YjgF_endoribonc PF14588.6 GAX13767.1 - 2e-21 76.7 0.0 2.2e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 GAX13767.1 - 2e-15 56.9 0.0 4.1e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 Endoribonuclease L-PSP HpaB_N PF11794.8 GAX13767.1 - 0.052 13.2 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal HECT PF00632.25 GAX13768.1 - 6.5e-81 272.2 0.0 8.5e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CAP_N PF01213.19 GAX13768.1 - 5.7 6.3 10.2 1.3 8.4 5.8 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal 2OG-FeII_Oxy_3 PF13640.6 GAX13769.1 - 1.4e-16 61.1 0.1 3.3e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX13769.1 - 0.00082 19.8 0.0 0.003 18.0 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5063 PF16702.5 GAX13769.1 - 0.011 16.1 0.3 0.026 14.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) DUF5617 PF18493.1 GAX13769.1 - 0.062 13.4 0.2 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) PBP1_TM PF14812.6 GAX13769.1 - 0.1 13.0 5.2 0.24 11.8 5.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 GAX13769.1 - 0.39 8.9 8.1 0.54 8.4 8.1 1.3 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 GAX13769.1 - 0.61 8.1 5.5 0.9 7.5 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 GAX13769.1 - 1 8.7 10.6 1.5 8.2 10.6 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GAX13769.1 - 3.5 6.9 11.6 5.9 6.1 11.6 1.2 1 0 0 1 1 1 0 BUD22 MBD PF01429.19 GAX13770.1 - 2e-05 24.2 0.1 3.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain HTH_3 PF01381.22 GAX13770.1 - 0.06 13.4 0.1 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix EMP70 PF02990.16 GAX13771.1 - 2.8e-190 633.4 7.5 3.6e-190 633.0 7.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF1043 PF06295.12 GAX13771.1 - 0.037 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) zf-MYND PF01753.18 GAX13773.1 - 7.9e-13 48.3 34.5 8.1e-09 35.4 16.6 3.0 3 0 0 3 3 3 2 MYND finger DUF3493 PF11998.8 GAX13774.1 - 4.5e-21 74.8 0.7 9e-21 73.8 0.3 1.7 2 0 0 2 2 2 1 Low psii accumulation1 / Rep27 DnaB PF00772.21 GAX13774.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Abhydrolase_1 PF00561.20 GAX13775.1 - 0.0014 18.3 0.6 0.0027 17.4 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX13775.1 - 0.019 14.3 0.4 0.16 11.2 0.4 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S51 PF03575.17 GAX13776.1 - 8.8e-13 48.4 0.0 3.9e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family S51 Enolase_like_N PF18374.1 GAX13776.1 - 0.016 14.6 0.0 3.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Enolase N-terminal domain-like LRR_4 PF12799.7 GAX13777.1 - 0.002 18.5 1.2 0.98 9.9 0.5 3.5 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) EF-hand_13 PF17958.1 GAX13778.1 - 4e-35 119.5 0.8 1.2e-33 114.8 0.1 3.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 GAX13778.1 - 2.7e-16 59.8 8.7 1.2e-13 51.3 0.6 4.4 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX13778.1 - 5.8e-06 25.5 2.1 0.018 14.5 0.0 5.0 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 GAX13778.1 - 2.8e-05 23.7 0.8 0.64 10.1 0.0 4.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.6 GAX13778.1 - 0.00022 20.5 2.5 0.0019 17.6 0.0 3.7 4 0 0 4 4 4 1 EF hand DUF4187 PF13821.6 GAX13778.1 - 0.023 14.4 0.4 0.058 13.2 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) EF-hand_8 PF13833.6 GAX13778.1 - 0.052 13.4 0.6 1.1 9.2 0.2 3.1 3 0 0 3 3 3 0 EF-hand domain pair RCC1 PF00415.18 GAX13780.1 - 1.8e-28 98.9 11.3 2.9e-10 40.6 0.1 6.2 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX13780.1 - 4.8e-28 96.3 9.3 1.8e-06 27.5 0.1 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 GAX13780.1 - 0.00052 20.2 0.1 0.0026 18.0 0.0 2.2 2 0 0 2 2 2 1 Putative heavy-metal chelation SNRNP27 PF08648.12 GAX13781.1 - 1.2e-25 89.3 3.4 1.7e-25 88.9 2.3 1.8 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Fer4 PF00037.27 GAX13783.1 - 1.8e-14 52.8 17.1 1.6e-08 34.0 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 GAX13783.1 - 4.8e-13 49.5 11.0 7.1e-13 48.9 11.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAX13783.1 - 4.9e-11 43.4 5.3 3.3e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 GAX13783.1 - 2.3e-09 37.2 21.2 4.9e-07 29.8 12.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 GAX13783.1 - 3.3e-09 36.7 31.9 1.6e-06 28.1 11.8 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAX13783.1 - 9e-09 35.4 10.7 1.4e-08 34.7 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAX13783.1 - 9.7e-09 35.5 3.4 0.00038 20.9 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAX13783.1 - 3.1e-07 30.1 12.7 0.0025 17.8 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 GAX13783.1 - 3.5e-07 30.0 18.0 0.00037 20.4 5.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 GAX13783.1 - 1.2e-05 25.4 11.7 0.00048 20.4 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GAX13783.1 - 0.00024 21.6 12.4 0.069 13.7 3.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 GAX13783.1 - 0.0093 16.2 5.5 0.84 9.9 0.4 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 GAX13783.1 - 0.025 15.1 15.2 0.65 10.6 2.7 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 GAX13783.1 - 0.044 13.9 4.6 0.25 11.5 0.3 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 GAX13783.1 - 0.1 12.8 8.5 2.4 8.4 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 GAX13783.1 - 0.11 13.5 17.2 0.32 12.0 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 GAX13783.1 - 0.73 10.7 11.3 2.6 9.0 1.8 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain TPT PF03151.16 GAX13784.1 - 7.3e-10 38.7 22.2 8.5e-10 38.4 22.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX13784.1 - 1.8e-07 31.4 27.0 7.6e-07 29.4 11.2 2.3 2 1 0 2 2 2 2 EamA-like transporter family Op_neuropeptide PF08035.11 GAX13784.1 - 0.15 11.9 0.8 0.31 10.9 0.1 1.9 2 0 0 2 2 2 0 Opioids neuropeptide PSII_Pbs27 PF13326.6 GAX13785.1 - 1e-37 129.6 0.7 1.5e-37 129.1 0.1 1.5 2 0 0 2 2 2 1 Photosystem II Pbs27 TAT_signal PF10518.9 GAX13785.1 - 0.00093 19.0 1.8 0.00093 19.0 1.8 2.4 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 GAX13785.1 - 0.1 11.9 0.4 0.32 10.4 0.1 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Herpes_glycop_H PF02489.16 GAX13785.1 - 0.23 10.0 0.3 0.75 8.2 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus glycoprotein H main domain Peptidase_M3 PF01432.20 GAX13786.1 - 2.5e-136 455.6 0.0 4.1e-136 454.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 GAX13786.1 - 0.015 15.0 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DUF3606 PF12244.8 GAX13786.1 - 0.54 10.2 2.7 0.85 9.6 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) PPR_long PF17177.4 GAX13787.1 - 1.2e-33 116.3 7.1 1.2e-31 109.7 7.1 2.1 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PRORP PF16953.5 GAX13787.1 - 2.1e-25 89.6 0.1 3.7e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Protein-only RNase P PPR_3 PF13812.6 GAX13787.1 - 2.1e-05 24.5 0.0 0.37 10.9 0.0 3.7 2 1 2 4 4 4 2 Pentatricopeptide repeat domain RNase_Zc3h12a PF11977.8 GAX13787.1 - 4.5e-05 23.3 0.0 0.00016 21.5 0.0 1.8 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_2 PF13041.6 GAX13787.1 - 5.4e-05 23.3 1.7 0.77 10.0 0.0 4.1 4 0 0 4 4 3 1 PPR repeat family PPR PF01535.20 GAX13787.1 - 0.00023 21.2 0.2 5 7.6 0.0 4.2 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.7 GAX13787.1 - 0.011 15.4 0.4 4.6 7.0 0.1 3.0 3 0 0 3 3 3 0 PPR repeat Wzy_C_2 PF11846.8 GAX13787.1 - 0.026 14.4 0.3 0.049 13.6 0.3 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal ATP13 PF12921.7 GAX13787.1 - 0.03 14.2 0.0 2.4 8.1 0.0 2.7 2 1 0 2 2 2 0 Mitochondrial ATPase expression BTAD PF03704.17 GAX13787.1 - 0.09 13.2 2.8 0.22 11.9 2.8 1.6 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 GAX13787.1 - 0.2 12.5 2.4 58 4.9 0.4 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Skp1 PF01466.19 GAX13788.1 - 2.6e-27 94.7 0.1 5e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAX13788.1 - 4.2e-18 65.3 0.3 8.5e-18 64.3 0.3 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 GAX13788.1 - 0.0023 18.1 1.4 0.021 15.0 0.2 2.1 1 1 1 2 2 2 1 BTB/POZ domain RMI1_C PF16099.5 GAX13788.1 - 0.032 14.1 0.3 0.07 13.0 0.2 1.6 1 1 1 2 2 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold DUF1450 PF07293.11 GAX13788.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) GRIP PF01465.20 GAX13790.1 - 8.1e-15 54.5 0.2 2.3e-14 53.0 0.2 1.9 1 0 0 1 1 1 1 GRIP domain SH3BGR PF04908.15 GAX13790.1 - 0.0022 18.1 0.1 0.077 13.2 0.0 3.3 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein HIP1_clath_bdg PF16515.5 GAX13790.1 - 0.025 15.2 1.4 0.025 15.2 1.4 8.6 3 1 6 9 9 9 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 GAX13790.1 - 1.9 7.1 65.7 0.0095 14.6 21.7 3.3 1 1 2 3 3 3 0 AAA domain DUF285 PF03382.14 GAX13791.1 - 1.6e-111 366.8 61.0 1.3e-32 112.0 12.0 3.3 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 6PF2K PF01591.18 GAX13792.1 - 1.2e-55 188.2 0.1 1.8e-55 187.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAX13792.1 - 1.5e-29 103.0 0.0 1.1e-28 100.3 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAX13792.1 - 1.3e-05 25.4 0.1 3.7e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF285 PF03382.14 GAX13793.1 - 5.8e-51 171.3 19.5 8.5e-27 93.3 9.1 2.5 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 DUF285 PF03382.14 GAX13794.1 - 9.8e-47 157.7 25.0 1.1e-25 89.8 8.8 2.6 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Peptidase_S8 PF00082.22 GAX13795.1 - 1.1e-38 133.1 0.1 1.5e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Subtilase family EF-hand_7 PF13499.6 GAX13799.1 - 1.4e-12 47.9 2.7 6.8e-07 29.6 0.2 2.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAX13799.1 - 2e-11 42.6 0.3 1.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX13799.1 - 8.8e-09 34.6 0.0 0.00047 19.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX13799.1 - 2.1e-08 33.3 0.1 0.0083 15.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 GAX13799.1 - 8.5e-05 22.5 1.5 0.28 11.2 0.0 2.7 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 GAX13799.1 - 0.00018 21.3 0.8 0.0067 16.3 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAX13799.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region IFT57 PF10498.9 GAX13801.1 - 0.052 12.5 0.3 0.1 11.5 0.0 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Tmemb_14 PF03647.13 GAX13802.1 - 3e-25 88.8 10.5 3.6e-25 88.5 10.5 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2157 PF09925.9 GAX13802.1 - 0.072 12.9 1.2 0.1 12.4 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF3918 PF13056.6 GAX13802.1 - 0.21 11.2 0.0 0.21 11.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) DUF5518 PF17647.1 GAX13802.1 - 0.94 9.6 11.9 0.13 12.4 2.8 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5518) PITH PF06201.13 GAX13803.1 - 2.1e-33 115.7 0.0 2.6e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain SQS_PSY PF00494.19 GAX13804.1 - 9.3e-24 84.3 0.7 1.3e-23 83.8 0.7 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase LRR_8 PF13855.6 GAX13805.1 - 2.5e-15 56.0 36.9 1.8e-06 27.6 1.3 6.8 1 1 9 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 GAX13805.1 - 4.4e-08 33.3 39.4 5.2e-05 23.5 0.2 8.2 4 2 3 10 10 10 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX13805.1 - 0.0017 18.6 27.0 16 6.5 0.1 11.1 11 1 1 12 12 12 1 Leucine Rich Repeat LRR_6 PF13516.6 GAX13805.1 - 0.092 12.8 19.7 0.31 11.2 0.6 7.8 9 0 0 9 9 9 0 Leucine Rich repeat PT PF04886.12 GAX13807.1 - 0.038 13.5 3.0 0.038 13.5 3.0 2.7 3 0 0 3 3 3 0 PT repeat Macoilin PF09726.9 GAX13808.1 - 0.061 11.9 3.7 0.075 11.6 3.7 1.2 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 GAX13808.1 - 0.36 10.8 4.7 1.6e+02 2.2 0.0 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region EphA2_TM PF14575.6 GAX13808.1 - 1 10.3 3.6 1.7 9.5 0.0 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 GAX13808.1 - 5.8 7.9 0.0 5.8 7.9 0.0 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) MFS_1 PF07690.16 GAX13809.1 - 0.019 13.9 0.1 0.033 13.1 0.1 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4083 PF13314.6 GAX13809.1 - 0.097 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) MFS_Mycoplasma PF07672.13 GAX13809.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter Insulin_TMD PF17870.1 GAX13810.1 - 0.085 12.9 0.5 0.18 11.9 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment OAD_gamma PF04277.13 GAX13810.1 - 1.9 9.1 3.2 1.9 9.1 0.0 2.3 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Fer2_4 PF13510.6 GAX13812.1 - 0.033 14.3 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Methyltransf_21 PF05050.12 GAX13813.1 - 3.7e-08 33.6 0.1 4.8e-07 29.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase FkbM domain Acetyltransf_10 PF13673.7 GAX13816.1 - 0.027 14.4 0.1 0.26 11.2 0.0 2.3 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain BBL5 PF07289.11 GAX13816.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Acetyltransf_1 PF00583.25 GAX13816.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GAX13816.1 - 0.091 13.4 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX13816.1 - 0.17 12.3 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PDDEXK_4 PF14281.6 GAX13817.1 - 0.032 14.4 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Acetyltransf_10 PF13673.7 GAX13817.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Endonuclease_1 PF04231.13 GAX13818.1 - 2.1e-14 53.8 0.1 4.7e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease I DUF5522 PF17653.1 GAX13820.1 - 3.9e-22 77.9 7.1 1.1e-21 76.5 7.1 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Peripla_BP_2 PF01497.18 GAX13820.1 - 8.8e-10 38.5 0.0 6e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Periplasmic binding protein Diphthami_syn_2 PF01902.17 GAX13820.1 - 5.8e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Diphthamide synthase Oxidored-like PF09791.9 GAX13820.1 - 0.24 11.1 3.2 0.72 9.6 3.2 1.8 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal CCDC154 PF15450.6 GAX13820.1 - 5.5 5.4 5.8 0.37 9.3 0.6 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 Abhydrolase_6 PF12697.7 GAX13821.1 - 1.4e-09 38.9 0.1 2.1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX13821.1 - 1.5e-07 31.3 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX13821.1 - 1.6e-05 24.3 0.0 9.3e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GAX13821.1 - 1.7e-05 24.8 0.0 9.7e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 GAX13821.1 - 4.8e-05 22.9 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase BAAT_C PF08840.11 GAX13821.1 - 0.00011 22.2 0.0 0.043 13.7 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GAX13821.1 - 0.00012 21.7 0.0 0.05 13.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family UPF0227 PF05728.12 GAX13821.1 - 0.0076 16.2 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Esterase PF00756.20 GAX13821.1 - 0.012 15.2 0.0 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Say1_Mug180 PF10340.9 GAX13821.1 - 0.036 12.9 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Thioesterase PF00975.20 GAX13821.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain DUF5325 PF17259.2 GAX13822.1 - 0.14 12.1 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5325) CbtA PF09490.10 GAX13822.1 - 0.27 11.0 0.1 0.4 10.4 0.1 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) UPF0061 PF02696.14 GAX13823.1 - 1.1e-70 238.7 1.2 5.8e-41 140.7 0.4 2.1 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family DUF445 PF04286.12 GAX13823.1 - 0.072 12.9 0.2 5 6.8 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF445) Response_reg PF00072.24 GAX13824.1 - 1.2e-24 86.6 0.3 2.1e-24 85.8 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAX13824.1 - 7.6e-24 84.4 0.0 2.7e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAX13824.1 - 2.5e-10 40.2 0.0 1.1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX13824.1 - 0.0019 18.0 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5423 PF17461.2 GAX13824.1 - 0.039 12.8 0.0 0.092 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Response_reg PF00072.24 GAX13825.1 - 1.6e-22 79.8 0.2 4.4e-22 78.4 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAX13825.1 - 3.3e-22 79.1 0.1 1e-21 77.5 0.0 1.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAX13825.1 - 2.3e-09 37.1 0.0 8.9e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX13825.1 - 0.0023 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF308 PF03729.13 GAX13825.1 - 0.035 14.4 1.9 0.079 13.3 1.9 1.5 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Pkinase PF00069.25 GAX13826.1 - 1.1e-36 126.6 0.0 2.4e-35 122.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13826.1 - 6e-27 94.6 0.0 3.8e-26 91.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX13826.1 - 0.0017 17.8 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX13826.1 - 0.034 14.1 0.0 0.065 13.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyco_tranf_2_3 PF13641.6 GAX13827.1 - 6.5e-16 58.9 0.1 1.9e-15 57.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX13827.1 - 7.3e-12 45.4 0.0 2.5e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 GAX13827.1 - 0.00022 21.2 5.2 0.00022 21.2 5.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 ET PF01684.16 GAX13827.1 - 3.4 8.1 6.6 0.49 10.8 0.5 2.8 3 0 0 3 3 3 0 ET module Promethin PF16015.5 GAX13827.1 - 3.4 7.6 8.5 7 6.6 8.5 1.4 1 0 0 1 1 1 0 Promethin MgtE PF01769.16 GAX13827.1 - 6.9 7.1 8.8 0.59 10.5 3.1 2.0 2 0 0 2 2 2 0 Divalent cation transporter Peptidase_M43 PF05572.13 GAX13828.1 - 1.5e-15 57.5 0.0 2.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX13828.1 - 2.1e-05 24.8 0.0 0.00017 21.8 0.0 2.4 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX13828.1 - 0.0015 18.2 0.5 0.01 15.5 0.0 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX13828.1 - 0.041 14.4 0.0 0.09 13.3 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX13828.1 - 0.098 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX13828.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Glyco_tranf_2_3 PF13641.6 GAX13830.1 - 4.2e-21 75.9 0.0 7.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAX13830.1 - 1.4e-14 54.5 2.1 1.4e-14 54.5 2.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAX13830.1 - 6.1e-14 52.2 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 WBP-1 PF11669.8 GAX13830.1 - 0.0089 16.7 0.2 0.22 12.2 0.1 2.6 2 0 0 2 2 2 1 WW domain-binding protein 1 Ins134_P3_kin PF05770.11 GAX13831.1 - 2.7e-29 102.1 0.0 7.4e-29 100.7 0.0 1.7 1 1 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Peptidase_C12 PF01088.21 GAX13832.1 - 4.2e-61 206.4 0.0 7.5e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 GAX13832.1 - 5.5e-17 61.4 3.1 5.5e-17 61.4 3.1 2.3 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolases PolyA_pol PF01743.20 GAX13833.1 - 6.5e-21 75.1 0.0 1.3e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 GAX13833.1 - 0.12 12.3 0.2 1.2 9.1 0.3 2.3 2 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative zf-C3HC4_3 PF13920.6 GAX13834.1 - 6e-08 32.4 8.0 6e-08 32.4 8.0 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX13834.1 - 0.00013 21.7 9.2 0.00013 21.7 9.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX13834.1 - 0.00047 20.4 9.3 0.00047 20.4 9.3 2.9 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 GAX13834.1 - 0.0023 17.8 7.5 0.0023 17.8 7.5 3.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) HNOB PF07700.15 GAX13835.1 - 8.8e-08 32.3 0.0 9.5e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Haem-NO-binding Sulfakinin PF08257.11 GAX13835.1 - 1.2 9.4 9.4 25 5.4 0.2 4.2 4 0 0 4 4 4 0 Sulfakinin family Pyr_redox_2 PF07992.14 GAX13836.1 - 2.1e-46 158.5 0.1 3.6e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 GAX13836.1 - 9.4e-20 70.5 0.0 3.8e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 GAX13836.1 - 1.5e-16 60.3 0.0 2.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 GAX13836.1 - 3e-16 59.7 1.5 1.2e-12 48.2 0.4 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 GAX13836.1 - 5.1e-14 52.3 5.3 1.5e-09 38.1 4.7 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 GAX13836.1 - 4.4e-11 42.6 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 GAX13836.1 - 2.8e-10 39.9 0.0 5.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 GAX13836.1 - 8e-08 32.1 0.0 2.2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain AlaDh_PNT_C PF01262.21 GAX13836.1 - 0.00067 19.0 0.0 0.022 14.1 0.2 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAX13836.1 - 0.0036 16.4 0.4 0.16 11.0 0.5 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 GAX13836.1 - 0.0037 16.4 0.0 1.9 7.6 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAX13836.1 - 0.013 14.8 0.6 1.2 8.3 0.5 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX13836.1 - 0.3 10.1 1.6 4.9 6.1 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain Presenilin PF01080.17 GAX13837.1 - 9.9 4.8 7.2 12 4.5 7.2 1.2 1 0 0 1 1 1 0 Presenilin SGT1 PF07093.11 GAX13839.1 - 2.4e-18 65.9 7.2 4.6e-14 51.8 0.2 2.3 2 1 0 2 2 2 2 SGT1 protein RseA_C PF03873.13 GAX13839.1 - 0.025 14.8 0.1 0.066 13.5 0.1 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain PP2C PF00481.21 GAX13840.1 - 8.2e-53 179.7 0.0 1.2e-52 179.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX13840.1 - 6.7e-05 22.6 0.0 0.00023 20.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C TMEM70 PF06979.12 GAX13841.1 - 2.9e-08 34.2 0.5 0.00069 20.0 0.0 2.1 2 0 0 2 2 2 2 Assembly, mitochondrial proton-transport ATP synth complex Asp PF00026.23 GAX13842.1 - 3.4e-25 89.1 0.3 8.1e-25 87.9 0.0 1.6 1 1 1 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX13842.1 - 0.0096 15.7 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal HSA PF07529.13 GAX13843.1 - 2.2e-10 40.7 0.4 6.6e-10 39.2 0.4 1.7 1 0 0 1 1 1 1 HSA Myb_DNA-bind_6 PF13921.6 GAX13843.1 - 0.017 15.3 0.2 0.059 13.6 0.2 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAX13843.1 - 0.032 14.4 0.6 0.14 12.3 0.6 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain RHD3 PF05879.12 GAX13844.1 - 0.00031 19.0 0.9 0.00039 18.7 0.1 1.4 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) FAD_binding_3 PF01494.19 GAX13845.1 - 4.9e-18 65.5 0.1 2.3e-08 33.7 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAX13845.1 - 0.00035 20.7 0.2 0.00079 19.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DnaJ_CXXCXGXG PF00684.19 GAX13845.1 - 0.0038 17.6 0.7 0.0092 16.3 0.7 1.6 1 0 0 1 1 1 1 DnaJ central domain Pyr_redox PF00070.27 GAX13845.1 - 0.032 14.8 0.0 0.69 10.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX13845.1 - 0.058 12.5 0.1 0.093 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 GAX13845.1 - 0.072 12.3 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX13845.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FH2 PF02181.23 GAX13847.1 - 1e-50 172.9 15.8 4.3e-49 167.6 15.8 2.1 1 1 0 1 1 1 1 Formin Homology 2 Domain Chlamy_scaf PF09675.10 GAX13847.1 - 0.0059 16.9 0.1 0.051 13.9 0.0 2.4 2 0 0 2 2 2 1 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Cytadhesin_P30 PF07271.11 GAX13847.1 - 0.11 12.0 0.6 0.21 11.1 0.6 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 UPF1_Zn_bind PF09416.10 GAX13849.1 - 2.5e-61 206.1 5.4 4.3e-61 205.3 4.4 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 GAX13849.1 - 2e-56 190.8 0.0 3.2e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX13849.1 - 8.5e-48 163.4 2.8 1.4e-28 100.4 0.1 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 GAX13849.1 - 2.8e-18 66.0 0.0 4.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GAX13849.1 - 4.8e-16 59.0 1.3 2.2e-15 56.9 1.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX13849.1 - 1.7e-11 44.7 0.2 8.1e-11 42.5 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX13849.1 - 2.7e-05 24.4 0.1 8.6e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 GAX13849.1 - 3.8e-05 23.6 0.4 0.00011 22.1 0.4 1.8 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 GAX13849.1 - 6.4e-05 23.0 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAX13849.1 - 0.00013 21.6 0.4 0.0026 17.3 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 GAX13849.1 - 0.00015 21.2 2.1 0.00082 18.7 0.2 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 GAX13849.1 - 0.0014 18.4 0.2 0.0032 17.2 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.14 GAX13849.1 - 0.0017 17.6 0.1 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase PhoH PF02562.16 GAX13849.1 - 0.0044 16.5 0.1 0.0098 15.4 0.0 1.6 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.18 GAX13849.1 - 0.0048 16.7 0.3 3.2 7.4 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 GAX13849.1 - 0.012 16.0 0.5 0.028 14.8 0.1 1.9 2 0 0 2 2 1 0 AAA ATPase domain SRP54 PF00448.22 GAX13849.1 - 0.015 14.9 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 GAX13849.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.14 GAX13849.1 - 0.044 13.8 0.2 0.081 12.9 0.2 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_10 PF12846.7 GAX13849.1 - 0.055 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.14 GAX13849.1 - 0.11 12.5 0.1 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ribosomal_S13_N PF08069.12 GAX13849.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_7 PF12775.7 GAX13849.1 - 0.15 11.5 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PALP PF00291.25 GAX13850.1 - 2.1e-67 227.6 0.2 2.4e-67 227.4 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_20 PF00982.21 GAX13851.1 - 2.7e-116 389.0 0.0 1.3e-103 347.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAX13851.1 - 1.4e-41 142.2 0.0 3.3e-41 141.0 0.0 1.5 2 0 0 2 2 2 1 Trehalose-phosphatase peroxidase PF00141.23 GAX13853.1 - 3.1e-44 151.4 0.0 3.9e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DUF1077 PF06417.12 GAX13854.1 - 1.3e-28 99.4 7.3 1.8e-28 98.9 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Polysacc_synt_3 PF13440.6 GAX13854.1 - 0.037 13.3 4.3 0.034 13.3 3.7 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein CK_II_beta PF01214.18 GAX13855.1 - 1.8e-64 216.9 0.0 2.2e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF35_N PF12172.8 GAX13855.1 - 0.046 13.6 0.5 0.1 12.5 0.5 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RNase_PH PF01138.21 GAX13856.1 - 1.3e-30 106.6 0.0 4.8e-19 69.2 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX13856.1 - 5.8e-17 61.5 0.7 3e-10 40.0 0.0 2.9 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 GAX13856.1 - 1.3e-07 31.3 0.1 4.2e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 KH domain S1 PF00575.23 GAX13856.1 - 2.7e-06 27.6 0.3 8e-06 26.1 0.3 1.8 1 1 0 1 1 1 1 S1 RNA binding domain PNPase PF03726.14 GAX13856.1 - 0.00017 22.0 0.1 0.00035 21.0 0.1 1.6 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_5 PF13184.6 GAX13856.1 - 0.017 15.2 0.1 0.039 14.0 0.1 1.6 1 0 0 1 1 1 0 NusA-like KH domain Sulfotransfer_2 PF03567.14 GAX13857.1 - 8.3e-08 32.4 0.5 1.5e-07 31.6 0.5 1.5 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAX13857.1 - 0.072 12.0 0.2 0.2 10.5 0.2 1.7 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase AAA PF00004.29 GAX13858.1 - 9.3e-35 119.9 0.0 1.8e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX13858.1 - 7e-08 33.0 0.3 3.7e-06 27.4 0.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX13858.1 - 1.2e-06 28.8 0.2 0.00028 21.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX13858.1 - 4.2e-06 26.8 0.2 1.8e-05 24.7 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX13858.1 - 5e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 GAX13858.1 - 0.00055 19.6 0.9 0.056 13.0 0.1 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAX13858.1 - 0.00091 18.7 0.1 0.0019 17.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GAX13858.1 - 0.00099 19.1 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 GAX13858.1 - 0.0013 19.2 0.0 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX13858.1 - 0.0017 18.9 0.0 0.0045 17.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_lid_3 PF17862.1 GAX13858.1 - 0.0019 18.0 0.5 0.0046 16.7 0.5 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 GAX13858.1 - 0.002 18.3 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAX13858.1 - 0.002 17.9 0.0 0.0066 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAX13858.1 - 0.003 17.9 0.0 0.0083 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 GAX13858.1 - 0.003 17.5 0.0 0.012 15.6 0.0 1.8 2 1 0 2 2 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 GAX13858.1 - 0.0035 17.3 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 GAX13858.1 - 0.0038 17.0 0.1 0.016 15.0 0.0 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 GAX13858.1 - 0.0041 17.0 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAX13858.1 - 0.0098 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 GAX13858.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Chi-conotoxin PF16981.5 GAX13858.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily Viral_helicase1 PF01443.18 GAX13858.1 - 0.057 13.2 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 GAX13858.1 - 0.059 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAX13858.1 - 0.083 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 GAX13858.1 - 0.12 12.1 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 GAX13858.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 GAX13859.1 - 9.2e-40 136.6 12.9 1.3e-39 136.1 12.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L12 PF00542.19 GAX13860.1 - 1.3e-24 86.3 6.0 1.3e-24 86.3 6.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 GAX13860.1 - 4.3e-07 29.5 0.5 3e-05 23.7 0.2 2.5 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain Aldedh PF00171.22 GAX13861.1 - 9.1e-130 433.2 0.0 1.1e-129 432.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L12 PF00542.19 GAX13862.1 - 9.2e-25 86.8 4.8 1.7e-24 85.9 4.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Unstab_antitox PF09720.10 GAX13862.1 - 0.019 15.0 0.0 9.1 6.4 0.1 2.5 2 0 0 2 2 2 0 Putative addiction module component Amino_oxidase PF01593.24 GAX13863.1 - 1.4e-68 232.3 0.0 1.7e-68 232.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX13863.1 - 1e-17 64.1 0.0 1.9e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX13863.1 - 2.2e-09 37.4 0.0 0.00031 20.4 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX13863.1 - 1.6e-07 31.7 0.0 0.0016 18.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAX13863.1 - 2.5e-06 26.6 0.0 0.0019 17.1 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 GAX13863.1 - 1.8e-05 24.1 0.0 6.9e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAX13863.1 - 6.3e-05 21.6 0.1 0.00013 20.6 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like HI0933_like PF03486.14 GAX13863.1 - 0.00041 19.2 0.1 0.004 15.9 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAX13863.1 - 0.0018 17.5 0.3 0.0098 15.0 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 GAX13863.1 - 0.0047 16.2 0.2 0.04 13.1 0.1 2.3 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 GAX13863.1 - 0.0061 16.0 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAX13863.1 - 0.02 14.2 0.1 0.062 12.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family IlvN PF07991.12 GAX13863.1 - 0.11 12.0 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Chitin_synth_2 PF03142.15 GAX13864.1 - 8e-160 532.9 2.4 1.2e-159 532.4 2.4 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 GAX13864.1 - 1.4e-12 48.0 8.0 4.4e-12 46.3 8.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX13864.1 - 1.5e-12 47.9 0.2 5.5e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 GAX13864.1 - 4.4e-11 42.8 0.1 2.3e-08 34.0 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 GAX13864.1 - 9.6e-06 25.5 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX13864.1 - 0.00012 21.6 0.4 0.096 12.2 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 GAX13865.1 - 1.9e-169 564.7 4.7 2.8e-169 564.1 4.7 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 GAX13865.1 - 1.3e-12 47.7 0.2 3.1e-10 40.0 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAX13865.1 - 5e-12 46.1 10.9 1.2e-11 44.9 10.9 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX13865.1 - 6.2e-12 45.9 0.7 8.2e-08 32.4 0.2 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX13865.1 - 1.5e-06 28.1 0.0 0.0093 15.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX13865.1 - 0.0014 18.2 0.2 0.093 12.2 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 ubiquitin PF00240.23 GAX13866.1 - 1.1e-68 226.9 5.0 1.2e-33 114.7 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 GAX13866.1 - 4.6e-33 112.9 6.5 5.3e-16 58.2 0.7 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX13866.1 - 3.7e-13 49.7 1.1 7.1e-05 23.2 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX13866.1 - 1.2e-08 34.7 0.2 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX13866.1 - 1.8e-07 31.2 0.2 0.033 14.3 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAX13866.1 - 1.9e-07 31.3 0.2 0.025 14.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 GAX13866.1 - 4.8e-06 27.1 0.1 0.13 12.8 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX13866.1 - 0.00016 21.7 6.6 9 6.4 0.0 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 GAX13866.1 - 0.0016 18.3 0.0 1.7 8.4 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 GAX13866.1 - 0.015 15.7 0.0 11 6.5 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2870) TmoB PF06234.12 GAX13866.1 - 0.076 13.1 0.5 19 5.4 0.1 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) FlgD_ig PF13860.6 GAX13866.1 - 0.11 12.3 0.7 20 5.1 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain FERM_f0 PF16511.5 GAX13866.1 - 0.14 12.5 2.0 42 4.5 0.2 3.5 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM DUF969 PF06149.12 GAX13866.1 - 0.15 11.4 0.0 5.8 6.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Abhydrolase_1 PF00561.20 GAX13868.1 - 2.5e-16 60.1 0.0 4.3e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX13868.1 - 1e-15 57.6 0.0 1.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX13868.1 - 3e-13 50.9 0.0 3.6e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GAX13868.1 - 7.1e-05 23.0 0.0 0.00013 22.1 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 GAX13868.1 - 0.00012 22.1 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 GAX13868.1 - 0.00095 18.7 0.0 0.0062 16.0 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 GAX13868.1 - 0.0061 16.4 0.0 2.2 8.1 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase Ndr PF03096.14 GAX13868.1 - 0.026 13.2 0.0 0.16 10.7 0.0 1.8 2 0 0 2 2 2 0 Ndr family Abhydrolase_2 PF02230.16 GAX13868.1 - 0.049 13.4 0.0 1.2 8.9 0.0 2.3 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase COG4 PF08318.12 GAX13869.1 - 9e-24 84.2 0.1 1.5e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 COG4 transport protein COG6 PF06419.11 GAX13869.1 - 0.0018 16.6 0.7 0.0045 15.3 0.7 1.6 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 GAS PF13851.6 GAX13869.1 - 0.033 13.6 1.6 0.11 11.8 1.6 1.9 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 GAX13869.1 - 0.15 11.4 5.2 0.56 9.5 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SNF2_N PF00176.23 GAX13870.1 - 1.1e-14 53.9 0.4 9e-14 51.0 0.4 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX13870.1 - 8.9e-12 45.3 0.0 1.9e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX13870.1 - 0.00059 19.6 0.2 0.014 15.1 0.1 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 GAX13870.1 - 0.00086 19.3 0.0 0.0064 16.5 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAX13870.1 - 0.069 12.8 0.0 0.26 10.9 0.0 2.0 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Bestrophin PF01062.21 GAX13871.1 - 2e-45 155.4 0.1 2.7e-45 155.0 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SNase PF00565.17 GAX13871.1 - 0.0094 16.4 0.0 0.09 13.3 0.0 2.2 2 0 0 2 2 2 1 Staphylococcal nuclease homologue GGACT PF06094.12 GAX13872.1 - 0.056 14.0 0.0 0.12 13.0 0.0 1.6 1 1 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like Dus PF01207.17 GAX13873.1 - 6.2e-46 156.9 0.0 1.1e-44 152.9 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Choline_transpo PF04515.12 GAX13874.1 - 7.8e-85 284.9 36.2 7.8e-85 284.9 36.2 2.5 3 0 0 3 3 3 1 Plasma-membrane choline transporter bZIP_1 PF00170.21 GAX13875.1 - 0.014 15.4 0.5 0.014 15.4 0.5 1.9 2 0 0 2 2 2 0 bZIP transcription factor Kinesin PF00225.23 GAX13876.1 - 3.4e-90 302.3 0.4 3.4e-90 302.3 0.4 3.0 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAX13876.1 - 1.5e-37 128.9 0.0 6.5e-36 123.5 0.0 3.4 2 1 0 2 2 2 1 Microtubule binding DUF5082 PF16888.5 GAX13876.1 - 0.0088 16.3 12.3 0.0088 16.3 12.3 5.7 3 2 2 5 5 5 1 Domain of unknown function (DUF5082) DUF3287 PF11690.8 GAX13876.1 - 2.8 7.7 7.5 0.94 9.2 2.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) Proteasome PF00227.26 GAX13877.1 - 4.3e-51 173.1 0.0 5.2e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX13877.1 - 4.3e-13 48.7 0.0 1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pribosyltran PF00156.27 GAX13878.1 - 3e-19 69.1 0.0 4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 GAX13878.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.6 GAX13878.1 - 0.0038 16.7 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF1824 PF08854.10 GAX13878.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) Xpo1 PF08389.12 GAX13879.1 - 5.9e-11 42.6 0.0 1.3e-09 38.3 0.0 3.4 3 1 0 3 3 3 1 Exportin 1-like protein Epimerase PF01370.21 GAX13880.1 - 3.6e-09 36.4 0.0 5.8e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX13880.1 - 2.6e-06 27.5 0.0 4.5e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX13880.1 - 4e-05 22.8 0.0 8.3e-05 21.7 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAX13880.1 - 0.00085 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAX13880.1 - 0.0012 18.0 0.0 0.0028 16.8 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 GAX13880.1 - 0.037 14.0 0.1 0.18 11.7 0.1 2.0 1 1 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 GAX13880.1 - 0.042 13.0 0.1 5.7 6.0 0.1 2.2 2 0 0 2 2 2 0 Male sterility protein POR PF01558.18 GAX13880.1 - 0.075 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase LPD22 PF18834.1 GAX13880.1 - 0.11 12.7 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 GIDA PF01134.22 GAX13881.1 - 1.9e-134 448.7 0.0 4.5e-133 444.1 0.0 2.2 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 GAX13881.1 - 1.1e-60 205.4 0.2 1.8e-60 204.8 0.2 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_binding_2 PF00890.24 GAX13881.1 - 3.8e-08 32.8 5.4 1.8e-05 24.0 2.7 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 GAX13881.1 - 9.3e-08 31.8 0.2 1.8e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX13881.1 - 4.5e-05 22.8 2.8 0.00015 21.1 2.8 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX13881.1 - 0.0014 18.0 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX13881.1 - 0.0037 17.8 0.3 0.0084 16.6 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX13881.1 - 0.005 16.2 0.8 0.005 16.2 0.8 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX13881.1 - 0.029 13.9 2.9 0.52 9.8 1.3 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAX13881.1 - 0.036 13.3 1.2 0.063 12.5 0.1 1.9 2 0 0 2 2 2 0 Thi4 family PPO1_KFDV PF12143.8 GAX13881.1 - 0.073 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) FAD_binding_3 PF01494.19 GAX13881.1 - 0.099 11.9 0.3 0.22 10.8 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAX13881.1 - 0.14 10.8 6.8 0.055 12.2 0.9 2.9 4 0 0 4 4 4 0 HI0933-like protein NAD_binding_8 PF13450.6 GAX13881.1 - 0.23 11.7 1.6 0.68 10.2 1.6 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX13881.1 - 0.42 9.6 3.7 0.48 9.4 1.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein SAP PF02037.27 GAX13882.1 - 8.2e-06 25.5 2.0 0.00067 19.4 0.0 2.9 3 0 0 3 3 3 2 SAP domain DUF3384 PF11864.8 GAX13882.1 - 0.0089 15.0 0.2 0.012 14.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) FANC_SAP PF18081.1 GAX13882.1 - 0.029 14.5 0.7 0.079 13.1 0.7 1.7 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain DUF1995 PF09353.10 GAX13883.1 - 1.9e-23 83.5 1.1 2.4e-23 83.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) Golgin_A5 PF09787.9 GAX13883.1 - 0.0068 15.9 1.6 0.0091 15.5 1.6 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3287 PF11690.8 GAX13883.1 - 0.053 13.3 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF1682 PF07946.14 GAX13883.1 - 0.13 11.5 2.6 0.2 10.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TUDOR_5 PF18359.1 GAX13884.1 - 1.4e-05 24.7 0.8 3.1e-05 23.6 0.8 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 GAX13884.1 - 0.0089 15.9 0.3 0.02 14.8 0.3 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Imm53 PF15580.6 GAX13884.1 - 0.13 12.0 0.3 0.35 10.6 0.3 1.7 1 0 0 1 1 1 0 Immunity protein 53 GDP_Man_Dehyd PF16363.5 GAX13885.1 - 6.1e-125 417.0 0.0 1.7e-62 211.8 0.0 3.0 2 2 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX13885.1 - 1.5e-117 391.3 0.0 1.2e-58 198.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX13885.1 - 7.3e-41 140.0 0.0 3.5e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAX13885.1 - 2.3e-33 115.5 0.0 1.5e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAX13885.1 - 6.3e-31 107.6 0.0 9.3e-16 57.8 0.0 3.5 2 2 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAX13885.1 - 1.6e-19 70.1 0.0 1.9e-08 33.8 0.0 3.0 2 2 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAX13885.1 - 2.7e-12 47.0 0.0 5.1e-05 23.3 0.0 3.3 2 2 0 2 2 2 2 NAD(P)H-binding KR PF08659.10 GAX13885.1 - 1.2e-11 44.8 1.2 2.4e-05 24.3 0.1 3.2 2 2 0 2 2 2 2 KR domain adh_short PF00106.25 GAX13885.1 - 2.5e-08 33.6 0.1 0.0013 18.3 0.0 2.9 3 0 0 3 3 3 2 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX13885.1 - 3.2e-06 27.4 0.0 0.063 13.5 0.0 2.3 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAX13885.1 - 3.8e-05 23.9 0.2 0.46 10.8 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Pyr_redox PF00070.27 GAX13885.1 - 9.7e-05 22.9 0.2 0.8 10.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAX13885.1 - 0.00018 21.5 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 GAX13885.1 - 0.00026 20.6 0.0 2 7.9 0.0 4.5 3 1 0 3 3 3 1 NmrA-like family ApbA PF02558.16 GAX13885.1 - 0.0027 17.4 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 GAX13885.1 - 0.0028 17.2 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_2 PF07992.14 GAX13885.1 - 0.009 15.3 0.0 3.7 6.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ssDBP_DBD PF18361.1 GAX13885.1 - 0.015 15.4 0.2 0.58 10.3 0.0 2.6 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain UDPG_MGDP_dh_N PF03721.14 GAX13885.1 - 0.05 13.2 0.9 6.1 6.4 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 GAX13885.1 - 0.07 12.7 0.0 6.2 6.3 0.0 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 GAX13885.1 - 0.09 12.1 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CreA PF05981.12 GAX13886.1 - 4.9e-35 120.4 0.2 9.3e-35 119.5 0.2 1.5 1 0 0 1 1 1 1 CreA protein MFS_1 PF07690.16 GAX13887.1 - 4e-29 101.7 14.7 5.9e-29 101.1 14.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SPX PF03105.19 GAX13887.1 - 2.2e-13 50.9 2.1 3.2e-06 27.3 0.3 2.3 2 0 0 2 2 2 2 SPX domain OATP PF03137.20 GAX13887.1 - 0.00027 19.4 9.6 0.0093 14.3 0.1 2.6 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 GAX13887.1 - 0.0012 17.8 12.6 0.0029 16.5 5.1 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter DUF4271 PF14093.6 GAX13887.1 - 0.76 9.7 10.8 0.37 10.7 6.2 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4271) Spermine_synth PF01564.17 GAX13888.1 - 1.2e-13 50.9 0.2 2.4e-13 49.9 0.2 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 GAX13888.1 - 0.02 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase Rad1 PF02144.16 GAX13889.1 - 5.1e-19 68.4 0.1 9e-19 67.6 0.1 1.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 MFS_1 PF07690.16 GAX13890.1 - 9.4e-26 90.6 39.2 1.9e-17 63.3 18.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Gemini_mov PF01708.16 GAX13890.1 - 0.11 12.2 0.7 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Geminivirus putative movement protein YtpI PF14007.6 GAX13890.1 - 7.6 6.7 15.6 0.64 10.2 0.2 3.9 3 1 1 4 4 4 0 YtpI-like protein HMMR_C PF15908.5 GAX13891.1 - 0.048 13.9 4.4 4.7 7.5 2.9 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Ndr PF03096.14 GAX13891.1 - 0.056 12.1 0.6 0.098 11.3 0.6 1.3 1 0 0 1 1 1 0 Ndr family Cnd1_N PF12922.7 GAX13891.1 - 0.077 12.8 3.5 0.75 9.6 1.5 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term HeH PF12949.7 GAX13891.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.9 1 0 0 1 1 1 0 HeH/LEM domain AAA_23 PF13476.6 GAX13891.1 - 0.12 12.9 5.8 0.043 14.3 2.4 2.0 2 0 0 2 2 2 0 AAA domain HBM PF16591.5 GAX13891.1 - 0.3 10.5 9.4 0.053 12.9 5.1 1.9 2 0 0 2 2 2 0 Helical bimodular sensor domain V_ATPase_I PF01496.19 GAX13891.1 - 0.3 8.9 3.5 0.53 8.1 3.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.18 GAX13891.1 - 0.32 10.3 3.5 0.73 9.1 3.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.15 GAX13891.1 - 0.89 9.4 18.8 4.5 7.1 0.9 3.6 2 1 1 3 3 3 0 Septum formation initiator KASH_CCD PF14662.6 GAX13891.1 - 3 7.6 17.2 0.42 10.4 10.9 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TMCO5 PF14992.6 GAX13891.1 - 3.4 7.2 13.6 0.45 10.1 8.1 2.0 2 0 0 2 2 2 0 TMCO5 family CTNNBL PF08216.11 GAX13892.1 - 1.1e-21 76.9 0.6 3e-21 75.5 0.6 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear TRAM_LAG1_CLN8 PF03798.16 GAX13892.1 - 6.1e-12 45.7 7.2 6.1e-12 45.7 7.2 1.7 2 0 0 2 2 2 1 TLC domain Gal-3-0_sulfotr PF06990.11 GAX13894.1 - 1.5e-06 27.4 1.8 0.015 14.2 1.8 2.5 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 GAX13894.1 - 0.055 13.4 1.4 0.091 12.7 0.3 1.8 2 1 0 2 2 2 0 Sulfotransferase family DUF2127 PF09900.9 GAX13894.1 - 0.08 13.2 1.0 17 5.7 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2127) Pkinase PF00069.25 GAX13896.1 - 1.5e-74 250.7 0.0 1.7e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13896.1 - 7.8e-32 110.6 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX13896.1 - 0.00043 19.3 0.0 0.0028 16.7 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAX13896.1 - 0.00081 18.8 0.1 0.02 14.2 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 GAX13896.1 - 0.011 15.7 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAX13896.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 GAX13896.1 - 0.18 11.1 0.3 0.41 10.0 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferric_reduct PF01794.19 GAX13897.1 - 2.9e-16 59.7 6.5 2.9e-16 59.7 6.5 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.6 GAX13897.1 - 3 8.5 9.5 26 5.5 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) tRNA-synt_1c PF00749.21 GAX13898.1 - 1.7e-88 296.5 0.0 7.9e-88 294.4 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAX13898.1 - 6.2e-36 123.9 0.0 1.3e-35 122.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain RTP PF02334.16 GAX13898.1 - 0.24 12.1 1.1 4.3 8.0 0.6 2.5 2 0 0 2 2 2 0 Replication terminator protein WW PF00397.26 GAX13899.1 - 5.3e-08 32.8 0.7 2.6e-07 30.6 0.7 2.3 1 0 0 1 1 1 1 WW domain RE_AspBHI_N PF18062.1 GAX13899.1 - 0.0057 16.2 0.1 0.015 14.8 0.1 1.7 1 0 0 1 1 1 1 Restriction endonuclease AspBHI N-terminal zf-RING_2 PF13639.6 GAX13900.1 - 7.4e-11 42.2 9.4 1.9e-10 40.9 9.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX13900.1 - 1.3e-06 28.0 5.6 5.2e-06 26.1 4.7 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GAX13900.1 - 4e-06 26.8 5.0 9.5e-06 25.6 5.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAX13900.1 - 4.5e-06 26.9 10.3 2e-05 24.8 10.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX13900.1 - 0.0001 22.0 9.1 0.0001 22.0 9.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX13900.1 - 0.00016 21.4 8.8 0.00046 20.0 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX13900.1 - 0.00018 21.5 1.6 0.00018 21.5 1.6 2.6 2 1 1 3 3 3 1 RING-type zinc-finger Nop25 PF09805.9 GAX13900.1 - 0.0027 18.2 0.9 0.0039 17.7 0.9 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) FANCL_C PF11793.8 GAX13900.1 - 0.0098 16.1 7.9 0.026 14.7 7.9 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX13900.1 - 0.012 15.2 8.1 0.012 15.2 8.1 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAX13900.1 - 0.051 13.5 7.5 0.13 12.3 7.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAX13900.1 - 0.054 13.6 4.3 0.054 13.6 4.3 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 GAX13900.1 - 0.89 9.7 11.2 2.2 8.5 11.2 1.7 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 GAX13900.1 - 1 9.3 8.0 2.2 8.2 8.0 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 GAX13900.1 - 2.4 8.5 8.1 5.3 7.4 8.1 1.7 1 0 0 1 1 1 0 RING-like domain Mpv17_PMP22 PF04117.12 GAX13901.1 - 3.5e-18 65.6 0.5 8.3e-18 64.4 0.5 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family CENP-S PF15630.6 GAX13902.1 - 2.2e-21 76.0 0.1 3.9e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAX13902.1 - 6.8e-10 39.0 0.1 1.1e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF4332 PF14229.6 GAX13902.1 - 0.00063 20.0 0.1 0.001 19.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) TFIID-31kDa PF02291.15 GAX13902.1 - 0.016 15.3 0.8 0.03 14.4 0.7 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 GAX13902.1 - 0.11 12.9 0.4 0.11 12.9 0.4 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Herpes_ori_bp PF02399.15 GAX13902.1 - 0.21 9.6 0.0 0.24 9.4 0.0 1.0 1 0 0 1 1 1 0 Origin of replication binding protein AAA_12 PF13087.6 GAX13903.1 - 3.6e-50 170.4 0.1 6.4e-50 169.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX13903.1 - 9.8e-42 143.5 0.0 2.3e-41 142.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX13903.1 - 3.2e-10 40.5 0.0 3.4e-09 37.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX13903.1 - 7.7e-10 38.8 0.1 5.5e-07 29.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 GAX13903.1 - 4.2e-07 29.9 0.3 0.15 11.7 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 GAX13903.1 - 0.00044 19.9 0.0 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 GAX13903.1 - 0.00057 19.7 0.1 0.0085 15.9 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 GAX13903.1 - 0.00079 19.5 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 GAX13903.1 - 0.0027 18.1 0.0 0.0098 16.3 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAX13903.1 - 0.0036 16.9 0.0 0.031 13.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 GAX13903.1 - 0.0049 16.7 0.0 0.099 12.5 0.0 2.4 2 0 0 2 2 2 1 Helicase UvrD_C PF13361.6 GAX13903.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 GAX13903.1 - 0.017 15.4 0.1 0.64 10.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain UvrD_C_2 PF13538.6 GAX13903.1 - 0.052 13.4 0.3 0.25 11.2 0.3 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.12 GAX13903.1 - 0.062 13.2 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 GAX13903.1 - 0.075 12.3 0.0 0.24 10.6 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 GAX13903.1 - 0.09 12.9 0.0 5.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAX13903.1 - 0.11 11.9 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Trypsin PF00089.26 GAX13904.1 - 2.4e-50 171.4 0.0 3.6e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX13904.1 - 0.0086 17.0 0.0 0.02 15.8 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain YceD PF02620.17 GAX13905.1 - 0.00077 19.6 2.0 0.017 15.2 1.4 2.8 2 1 0 2 2 2 1 Large ribosomal RNA subunit accumulation protein YceD DUF5364 PF17322.2 GAX13905.1 - 0.074 13.4 1.8 0.14 12.4 0.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5364) DHHA2 PF02833.14 GAX13907.1 - 1.1e-18 67.8 0.0 1.8e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 GAX13907.1 - 6.6e-10 39.1 0.1 1.2e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 DHH family Pkinase PF00069.25 GAX13908.1 - 4.7e-31 108.1 0.0 1.7e-29 103.0 0.0 2.5 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX13908.1 - 3.2e-27 95.5 0.0 5.8e-27 94.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_1_2 PF00155.21 GAX13909.1 - 9.7e-46 156.6 0.0 1.2e-45 156.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX13909.1 - 0.00014 20.5 0.0 0.00022 19.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PPR_2 PF13041.6 GAX13910.1 - 1.8e-12 47.2 7.6 0.00061 19.9 0.1 7.9 7 2 2 9 9 9 4 PPR repeat family PPR_long PF17177.4 GAX13910.1 - 2.4e-12 46.7 2.3 2.7e-07 30.1 0.1 4.0 2 1 3 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GAX13910.1 - 1.6e-09 37.7 0.0 0.00046 20.2 0.0 6.3 6 1 1 7 7 7 1 Pentatricopeptide repeat domain PPR PF01535.20 GAX13910.1 - 1.1e-08 34.7 9.1 0.00015 21.8 0.0 8.1 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 GAX13910.1 - 5.8e-05 22.7 0.9 2.7 7.7 0.1 5.7 6 0 0 6 6 6 2 PPR repeat S6PP_C PF08472.10 GAX13910.1 - 0.12 12.3 0.0 0.45 10.4 0.0 2.2 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal zf-C3HC4_2 PF13923.6 GAX13911.1 - 4.8e-09 35.9 9.8 9.7e-09 34.9 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX13911.1 - 2.1e-07 30.7 11.4 4.9e-07 29.5 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX13911.1 - 4.1e-07 29.8 7.7 7.7e-07 28.9 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 GAX13911.1 - 1.7e-06 27.8 1.5 1.7e-06 27.8 1.5 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_4 PF15227.6 GAX13911.1 - 1.8e-06 28.0 11.4 1.8e-06 28.0 11.4 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GAX13911.1 - 2.6e-06 27.3 11.3 5.1e-06 26.3 11.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAX13911.1 - 1.5e-05 25.3 10.3 1.5e-05 25.3 10.3 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX13911.1 - 1.5e-05 24.9 4.0 1.5e-05 24.9 4.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX13911.1 - 2.6e-05 24.0 9.8 4.9e-05 23.1 9.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf_CCCH_4 PF18345.1 GAX13911.1 - 8.6e-05 22.5 2.5 0.00019 21.4 2.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-Nse PF11789.8 GAX13911.1 - 0.002 17.9 5.7 0.0035 17.1 5.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 GAX13911.1 - 0.0065 16.1 5.8 0.012 15.3 5.8 1.4 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.7 GAX13911.1 - 0.0098 16.2 7.0 0.033 14.5 7.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 GAX13911.1 - 0.022 14.9 5.2 0.022 14.9 5.2 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Sporozoite_P67 PF05642.11 GAX13911.1 - 0.12 10.4 3.4 0.13 10.3 3.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FYVE_2 PF02318.16 GAX13911.1 - 0.16 12.2 5.3 0.4 10.9 5.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_6 PF14835.6 GAX13911.1 - 0.2 11.6 5.7 0.4 10.6 5.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCCH_4 PF18044.1 GAX13911.1 - 0.94 9.4 11.6 0.067 13.0 1.4 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger DUF4554 PF15091.6 GAX13911.1 - 0.95 8.3 4.9 1.6 7.6 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) 2OG-FeII_Oxy_3 PF13640.6 GAX13912.1 - 4.5e-16 59.5 0.0 7.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 GAX13912.1 - 2.6e-07 31.1 6.0 6.2e-07 29.8 6.0 1.7 1 0 0 1 1 1 1 ShK domain-like adh_short PF00106.25 GAX13913.1 - 1.6e-21 76.7 0.2 2e-12 47.0 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX13913.1 - 4.1e-20 72.4 0.1 1.9e-14 53.8 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX13913.1 - 0.13 12.2 0.2 0.47 10.3 0.1 1.9 2 0 0 2 2 2 0 KR domain CBM_6 PF03422.15 GAX13914.1 - 2.4e-73 244.3 3.3 1.7e-18 67.1 0.2 5.1 5 0 0 5 5 5 5 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX13914.1 - 4.4e-23 81.6 1.0 6.4e-06 26.3 0.0 5.4 5 0 0 5 5 5 4 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX13914.1 - 7e-16 58.6 6.2 0.0013 18.9 0.0 5.6 5 1 0 5 5 5 4 Carbohydrate binding module (family 35) Iron_transport PF10634.9 GAX13914.1 - 1.9e-06 28.2 0.0 1.2 9.4 0.0 4.6 5 0 0 5 5 5 2 Fe2+ transport protein CBM_4_9 PF02018.17 GAX13914.1 - 1.4e-05 25.4 2.2 0.9 9.8 0.0 4.7 4 1 0 4 4 4 2 Carbohydrate binding domain Endotoxin_C PF03944.14 GAX13914.1 - 0.0024 18.2 0.1 0.25 11.7 0.0 3.6 3 1 0 3 3 3 1 delta endotoxin DNA_photolyase PF00875.18 GAX13915.1 - 2e-20 73.5 0.0 3.3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Prominin PF05478.11 GAX13916.1 - 0.037 12.0 1.5 0.034 12.1 0.2 1.5 1 1 0 1 1 1 0 Prominin T3SSipB PF16535.5 GAX13916.1 - 0.45 11.0 7.6 2.7 8.5 2.5 2.8 2 1 0 2 2 2 0 Type III cell invasion protein SipB CDC37_N PF03234.14 GAX13916.1 - 0.74 10.7 9.7 0.089 13.7 2.1 2.5 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Syntaxin PF00804.25 GAX13916.1 - 2.8 7.5 12.6 0.048 13.3 1.3 2.9 2 1 1 3 3 3 0 Syntaxin LrgB PF04172.16 GAX13917.1 - 3.3e-33 115.0 18.7 3.3e-33 115.0 18.7 2.2 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 GAX13917.1 - 0.00075 19.4 4.8 0.00075 19.4 4.8 3.5 4 0 0 4 4 4 1 LrgA family PAS_9 PF13426.7 GAX13918.1 - 8.7e-16 58.1 0.0 2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 GAX13918.1 - 4.7e-07 29.8 6.5 1e-06 28.7 6.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX13918.1 - 7.1e-07 29.2 6.8 1.6e-06 28.1 6.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 GAX13918.1 - 0.0019 18.4 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 GAX13918.1 - 0.0042 17.1 0.2 0.024 14.6 0.0 2.1 2 1 1 3 3 3 1 PAS fold PAS_4 PF08448.10 GAX13918.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 PAS fold Mpp10 PF04006.12 GAX13918.1 - 0.027 12.9 9.7 0.037 12.5 9.7 1.1 1 0 0 1 1 1 0 Mpp10 protein PAS_8 PF13188.7 GAX13918.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain PBP1_TM PF14812.6 GAX13918.1 - 0.31 11.4 5.8 0.65 10.4 5.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPR_2 PF13041.6 GAX13919.1 - 6.5e-19 67.9 1.8 1.4e-05 25.2 0.1 7.4 7 1 1 8 8 8 3 PPR repeat family PPR_3 PF13812.6 GAX13919.1 - 1.9e-10 40.7 0.0 0.0018 18.3 0.0 3.3 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 GAX13919.1 - 2.8e-06 27.2 4.3 0.17 12.2 0.0 7.1 8 0 0 8 8 8 1 PPR repeat PPR_1 PF12854.7 GAX13919.1 - 0.0046 16.6 1.8 14 5.5 0.0 5.9 7 0 0 7 7 7 1 PPR repeat NusB PF01029.18 GAX13919.1 - 0.09 13.0 0.0 3.9 7.7 0.1 2.8 2 0 0 2 2 2 0 NusB family zf-RING_2 PF13639.6 GAX13920.1 - 1.1e-11 44.9 8.0 2.2e-11 43.9 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX13920.1 - 2e-07 31.2 6.6 4.9e-07 29.9 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX13920.1 - 2.2e-06 27.4 8.6 4e-06 26.6 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX13920.1 - 2.6e-06 27.4 4.4 5.2e-06 26.4 4.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX13920.1 - 3e-06 27.2 2.9 3e-06 27.2 2.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX13920.1 - 3.7e-06 26.7 9.0 6.8e-06 25.9 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX13920.1 - 3.9e-06 26.5 4.4 3.9e-06 26.5 4.4 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 GAX13920.1 - 6.7e-05 22.8 7.0 0.00012 21.9 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 GAX13920.1 - 0.00055 19.7 4.3 0.0012 18.6 4.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 GAX13920.1 - 0.02 14.5 5.8 0.043 13.4 5.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAX13920.1 - 0.036 14.2 10.3 0.061 13.5 10.3 1.4 1 0 0 1 1 1 0 RING-variant domain Tmpp129 PF10272.9 GAX13920.1 - 0.13 11.6 2.7 13 5.0 2.2 2.2 2 0 0 2 2 2 0 Putative transmembrane protein precursor FANCL_C PF11793.8 GAX13920.1 - 0.13 12.4 7.8 0.38 10.9 7.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 GAX13920.1 - 0.14 12.5 6.5 0.27 11.5 6.5 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 GAX13920.1 - 0.22 11.4 8.6 0.54 10.2 8.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trypsin PF00089.26 GAX13922.1 - 1.5e-48 165.6 0.1 2.4e-48 164.9 0.1 1.3 1 0 0 1 1 1 1 Trypsin DUF5577 PF17740.1 GAX13923.1 - 0.0019 17.9 0.3 0.0039 16.9 0.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5577) Tau95 PF09734.9 GAX13923.1 - 0.081 13.7 0.8 0.16 12.8 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain BNIP2 PF12496.8 GAX13923.1 - 0.21 12.1 3.6 0.21 12.0 1.3 2.0 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DER1 PF04511.15 GAX13924.1 - 1.3e-27 97.0 4.8 1.7e-27 96.6 4.8 1.2 1 0 0 1 1 1 1 Der1-like family TetR_C_20 PF17925.1 GAX13924.1 - 0.007 16.7 0.2 0.035 14.4 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain LAB_N PF07578.11 GAX13924.1 - 0.028 14.5 1.0 0.062 13.4 1.0 1.5 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Sporozoite_P67 PF05642.11 GAX13924.1 - 0.16 10.0 0.5 0.21 9.6 0.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 GAX13924.1 - 0.37 11.2 7.4 0.67 10.4 7.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RicinB_lectin_2 PF14200.6 GAX13925.1 - 5.5e-08 33.4 2.9 0.15 12.8 0.3 4.7 3 1 2 5 5 5 4 Ricin-type beta-trefoil lectin domain-like Fascin PF06268.13 GAX13925.1 - 3.7e-07 30.3 0.3 8.3e-05 22.8 0.1 3.3 2 1 1 3 3 3 2 Fascin domain FGF PF00167.18 GAX13925.1 - 0.0082 16.2 0.0 2.5 8.2 0.0 3.6 3 1 0 3 3 3 1 Fibroblast growth factor ABC_membrane PF00664.23 GAX13926.1 - 1.4e-53 182.3 6.7 8.7e-46 156.8 0.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX13926.1 - 1.4e-33 116.4 0.0 2.3e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAX13926.1 - 2.8e-06 26.9 0.1 0.00015 21.3 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAX13926.1 - 0.0012 19.3 0.2 0.0035 17.8 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 GAX13926.1 - 0.0082 15.4 0.4 0.04 13.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 GAX13926.1 - 0.014 14.9 0.0 0.098 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAX13926.1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 GAX13926.1 - 0.02 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX13926.1 - 0.023 15.0 0.2 0.12 12.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX13926.1 - 0.029 14.1 4.6 0.49 10.1 0.8 3.3 2 1 1 3 3 3 0 AAA domain SbcCD_C PF13558.6 GAX13926.1 - 0.087 13.1 0.3 0.89 9.8 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 GAX13926.1 - 0.11 12.3 0.0 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Wzy_C PF04932.15 GAX13926.1 - 0.43 10.2 3.6 0.91 9.1 2.9 1.9 2 1 0 2 2 2 0 O-Antigen ligase DUF2207 PF09972.9 GAX13926.1 - 0.44 9.3 1.7 0.81 8.4 0.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2614 PF11023.8 GAX13926.1 - 0.95 9.6 4.2 3.9 7.6 2.8 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain 2OG-FeII_Oxy_2 PF13532.6 GAX13927.1 - 8e-15 55.5 0.0 1.4e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.17 GAX13927.1 - 5.5e-13 48.9 1.6 2e-12 47.1 0.2 2.5 2 2 0 2 2 2 1 SAD/SRA domain S1 PF00575.23 GAX13928.1 - 3.1e-26 91.5 0.0 1.2e-16 60.8 0.1 2.5 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.6 GAX13928.1 - 0.0012 18.9 0.0 3.7 7.7 0.0 3.4 3 1 0 3 3 3 2 S1 domain RsgI_N PF12791.7 GAX13928.1 - 0.052 13.5 0.8 19 5.3 0.0 3.5 4 0 0 4 4 4 0 Anti-sigma factor N-terminus ABC_tran PF00005.27 GAX13929.1 - 3.7e-40 137.6 0.4 2.7e-22 79.8 0.0 3.4 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAX13929.1 - 1.5e-13 51.2 10.8 0.00085 19.2 0.3 4.7 3 2 2 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX13929.1 - 2.8e-08 33.4 0.0 0.0089 15.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 GAX13929.1 - 3.4e-08 33.2 3.4 0.0013 18.2 0.1 3.9 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX13929.1 - 1.3e-06 28.4 6.1 0.0021 17.8 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 GAX13929.1 - 1.5e-06 28.7 0.2 0.0014 19.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GAX13929.1 - 6.5e-06 26.8 8.1 0.3 11.5 0.0 3.4 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAX13929.1 - 9e-06 25.7 3.2 0.02 14.8 0.0 3.4 3 1 0 4 4 3 2 RsgA GTPase AAA_22 PF13401.6 GAX13929.1 - 9.1e-06 26.0 1.0 0.019 15.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 GAX13929.1 - 1.9e-05 24.0 1.6 0.09 11.9 0.0 2.7 2 1 0 2 2 2 2 G-protein alpha subunit NACHT PF05729.12 GAX13929.1 - 2.9e-05 24.0 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 GAX13929.1 - 0.00021 21.3 0.1 0.68 10.0 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 GAX13929.1 - 0.00022 21.2 3.3 0.00022 21.2 3.3 2.5 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 GAX13929.1 - 0.00044 20.8 0.1 0.19 12.3 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_24 PF13479.6 GAX13929.1 - 0.00099 18.9 0.0 0.29 10.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 GAX13929.1 - 0.0017 18.6 0.2 2.1 8.6 0.0 2.9 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 GAX13929.1 - 0.0029 17.9 0.1 0.64 10.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX13929.1 - 0.0043 17.2 0.0 3.5 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX13929.1 - 0.021 14.6 0.0 1.1 9.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAX13929.1 - 0.022 14.7 4.2 2.3 8.1 0.0 3.3 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea DLIC PF05783.11 GAX13929.1 - 0.034 13.0 0.1 1.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) FtsK_SpoIIIE PF01580.18 GAX13929.1 - 0.057 12.8 0.2 4.9 6.4 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAX13929.1 - 0.058 13.8 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 GAX13929.1 - 0.062 12.7 0.3 16 4.9 0.0 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_5 PF07728.14 GAX13929.1 - 0.065 13.2 0.1 0.62 10.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAX13929.1 - 0.075 12.5 0.0 0.51 9.8 0.0 2.3 3 0 0 3 3 2 0 P-loop containing dynein motor region MobB PF03205.14 GAX13929.1 - 0.13 12.1 2.1 3.5 7.5 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.25 GAX13929.1 - 0.14 11.8 0.0 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3987 PF13148.6 GAX13929.1 - 0.17 10.8 3.5 6.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PduV-EutP PF10662.9 GAX13929.1 - 0.18 11.6 0.4 27 4.5 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 GAX13929.1 - 0.23 11.5 0.1 0.23 11.5 0.1 3.4 3 2 1 4 4 4 0 Helicase HerA, central domain AAA_13 PF13166.6 GAX13929.1 - 0.23 10.0 12.3 2 7.0 0.0 3.4 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 GAX13929.1 - 1.7 8.4 4.8 2.4 7.9 0.0 3.3 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 GAX13929.1 - 8.4 6.8 7.7 17 5.9 0.3 3.5 4 1 0 4 4 3 0 AAA domain TRAF_BIRC3_bd PF16673.5 GAX13929.1 - 10 6.0 8.2 1.5 8.7 0.9 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain UbiA PF01040.18 GAX13930.1 - 4.9e-33 114.5 7.9 8.1e-33 113.8 7.3 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family EZH2_WD-Binding PF11616.8 GAX13931.1 - 0.97 9.6 3.4 4 7.6 0.1 2.6 3 0 0 3 3 3 0 WD repeat binding protein EZH2 WD40 PF00400.32 GAX13932.1 - 0.052 14.4 0.2 56 4.9 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAX13932.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AF-4 PF05110.13 GAX13932.1 - 0.071 11.2 13.0 0.094 10.8 13.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ANAPC4_WD40 PF12894.7 GAX13932.1 - 0.078 13.3 2.5 3.1 8.1 0.1 4.1 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX13932.1 - 0.24 10.0 0.0 0.24 10.0 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Nop14 PF04147.12 GAX13932.1 - 1.7 6.7 15.5 2.2 6.4 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAX13932.1 - 4.1 6.6 16.5 5.6 6.2 16.5 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAX13932.1 - 5.7 5.1 12.6 7.2 4.8 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 GAX13932.1 - 8.3 6.2 15.4 13 5.5 15.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 GAX13932.1 - 9.4 5.6 17.6 13 5.1 17.6 1.2 1 0 0 1 1 1 0 SDA1 CBF PF03914.17 GAX13933.1 - 2.3e-33 115.6 0.5 2.3e-33 115.6 0.5 1.9 2 0 0 2 2 2 1 CBF/Mak21 family Treacle PF03546.14 GAX13933.1 - 0.046 12.6 0.7 0.066 12.0 0.7 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle N1221 PF07923.13 GAX13933.1 - 0.074 12.2 0.2 0.17 11.0 0.2 1.5 1 0 0 1 1 1 0 N1221-like protein DWNN PF08783.11 GAX13934.1 - 8.5e-18 64.4 0.0 1.6e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 DWNN domain U-box PF04564.15 GAX13934.1 - 0.00011 22.4 0.0 0.00037 20.6 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-C3HC4_2 PF13923.6 GAX13934.1 - 0.00023 20.9 0.5 0.00037 20.3 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ubiquitin PF00240.23 GAX13935.1 - 4.1e-09 36.1 0.1 1.2e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Tudor-knot PF11717.8 GAX13935.1 - 0.009 15.9 2.2 0.021 14.7 2.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MBT PF02820.18 GAX13935.1 - 0.1 12.9 0.2 0.23 11.8 0.2 1.5 1 0 0 1 1 1 0 mbt repeat p450 PF00067.22 GAX13936.1 - 2.6e-75 253.9 0.0 3.6e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pentapeptide_4 PF13599.6 GAX13937.1 - 1.6e-12 47.4 3.9 6.3e-08 32.7 0.4 1.8 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 GAX13937.1 - 1.7e-11 43.5 7.7 2.9e-06 26.8 3.3 2.9 1 1 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 GAX13937.1 - 2.4e-07 30.8 1.9 7.2e-05 22.9 1.0 2.8 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) IBN_N PF03810.19 GAX13939.1 - 1.1e-10 41.3 1.5 1.6e-09 37.5 0.2 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 GAX13939.1 - 8.2e-09 34.8 0.0 2.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 GAX13939.1 - 1.8e-06 26.7 0.1 3.9e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus HEAT_2 PF13646.6 GAX13939.1 - 0.0016 18.8 2.3 3 8.3 0.5 4.2 4 1 0 4 4 4 2 HEAT repeats Xpo1 PF08389.12 GAX13939.1 - 0.002 18.2 0.3 0.082 13.0 0.1 2.9 2 0 0 2 2 2 1 Exportin 1-like protein TAF6_C PF07571.13 GAX13939.1 - 0.029 14.7 0.2 7.8 6.9 0.1 4.3 4 1 1 5 5 5 0 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 GAX13939.1 - 0.68 10.5 8.0 3.7 8.2 0.0 5.4 5 1 1 6 6 6 0 HEAT-like repeat MtrH PF02007.18 GAX13941.1 - 0.0044 16.2 0.0 0.0047 16.1 0.0 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit DUF1376 PF07120.11 GAX13941.1 - 0.057 13.7 0.6 1.6 9.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1376) Acetyltransf_1 PF00583.25 GAX13942.1 - 1.4e-12 47.8 0.0 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX13942.1 - 1.1e-09 38.3 0.1 1.7e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX13942.1 - 1e-08 35.5 0.2 1.6e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX13942.1 - 3e-07 30.3 0.0 6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAX13942.1 - 4.3e-06 26.9 0.2 6.2e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX13942.1 - 0.00043 20.4 0.1 0.00065 19.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX13942.1 - 0.04 14.0 0.1 0.078 13.1 0.1 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 GAX13942.1 - 0.072 12.6 1.3 0.11 11.9 1.3 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase Peptidase_M24 PF00557.24 GAX13944.1 - 5.3e-44 150.4 0.0 9.1e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 GAX13944.1 - 4.7e-42 143.8 0.6 3.4e-40 137.8 0.2 2.8 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 GAX13944.1 - 6.5e-24 83.8 1.6 9.1e-24 83.3 0.4 2.0 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAX13944.1 - 2.2e-18 67.2 0.1 2e-14 54.4 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF996 PF06195.13 GAX13945.1 - 1.1 9.5 9.0 3.2 8.0 9.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF996) Bac_DNA_binding PF00216.21 GAX13946.1 - 2e-23 82.4 0.4 2.8e-23 81.9 0.4 1.2 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 GAX13946.1 - 1.6e-06 28.2 0.1 1.9e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 GAX13946.1 - 0.0095 16.1 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_2 PF18175.1 GAX13946.1 - 0.049 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HTH_20 PF12840.7 GAX13947.1 - 0.13 12.4 0.1 0.34 11.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DJ-1_PfpI PF01965.24 GAX13949.1 - 7e-15 55.2 0.4 6.7e-14 52.0 0.4 2.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAX13949.1 - 4e-09 36.5 0.0 8.1e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 GAX13951.1 - 1.3e-14 54.3 0.1 6.2e-14 52.1 0.1 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAX13951.1 - 2.7e-10 40.3 0.0 3e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like Citrate_bind PF16114.5 GAX13952.1 - 7.7e-86 286.1 0.0 1.6e-85 285.1 0.0 1.6 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 GAX13952.1 - 3.6e-24 85.5 0.1 8.5e-22 77.7 0.1 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 GAX13952.1 - 1.1e-10 42.0 0.0 2.8e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 GAX13952.1 - 4.7e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 GAX13952.1 - 0.00023 21.0 0.1 0.00051 19.9 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase Glyco_tranf_2_4 PF13704.6 GAX13953.1 - 9.7e-06 26.0 1.1 2.3e-05 24.8 1.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX13953.1 - 0.013 15.2 0.8 0.027 14.2 0.2 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 92 LRR_8 PF13855.6 GAX13954.1 - 2.2e-09 36.9 11.1 5.3e-09 35.7 3.9 2.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAX13954.1 - 0.012 16.0 12.1 0.074 13.5 1.4 3.0 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAX13954.1 - 0.32 10.5 0.8 0.52 9.8 0.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeat SAP PF02037.27 GAX13955.1 - 5.9e-10 38.7 0.5 2.3e-09 36.8 0.5 2.0 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 GAX13955.1 - 0.14 11.9 0.3 0.39 10.5 0.1 1.9 2 0 0 2 2 2 0 HeH/LEM domain Telomere_Sde2_2 PF13297.6 GAX13955.1 - 0.5 10.0 2.5 0.39 10.4 0.3 2.0 2 0 0 2 2 2 0 Telomere stability C-terminal Trp_Tyr_perm PF03222.13 GAX13956.1 - 3.4e-38 131.7 15.3 5.4e-26 91.5 12.7 2.1 1 1 1 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 GAX13956.1 - 0.22 10.2 13.2 1.1 7.9 13.1 2.1 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein Mt_ATP-synt_D PF05873.12 GAX13957.1 - 1.4e-11 44.4 5.9 1.7e-11 44.2 5.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) F_bP_aldolase PF01116.20 GAX13957.1 - 0.046 13.2 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Na_H_Exchanger PF00999.21 GAX13958.1 - 7e-46 156.7 34.0 8.6e-46 156.4 34.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RAI16-like PF10257.9 GAX13958.1 - 0.17 10.7 0.2 14 4.4 0.0 2.2 2 0 0 2 2 2 0 Retinoic acid induced 16-like protein Pex24p PF06398.11 GAX13958.1 - 0.4 9.6 2.8 0.39 9.6 1.4 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin LCM PF04072.14 GAX13959.1 - 1.8e-09 37.8 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_2 PF00891.18 GAX13959.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Pyrid_oxidase_2 PF13883.6 GAX13960.1 - 1.5e-26 93.4 0.0 3.3e-26 92.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 GAX13960.1 - 2e-12 47.5 0.1 8.5e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 GAX13960.1 - 0.003 17.7 0.0 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CD20 PF04103.15 GAX13961.1 - 0.013 15.6 1.2 0.3 11.2 0.1 2.9 2 1 1 3 3 3 0 CD20-like family DHHC PF01529.20 GAX13961.1 - 0.016 15.3 0.6 4 7.5 0.0 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase Ctr PF04145.15 GAX13961.1 - 0.017 15.7 2.5 0.086 13.5 2.5 2.4 1 1 0 1 1 1 0 Ctr copper transporter family DUF4199 PF13858.6 GAX13961.1 - 0.022 15.2 0.9 0.022 15.2 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) AI-2E_transport PF01594.16 GAX13961.1 - 0.023 13.8 3.4 0.89 8.6 0.2 2.2 2 0 0 2 2 2 0 AI-2E family transporter ABC2_membrane_2 PF12679.7 GAX13961.1 - 0.097 11.9 1.2 0.27 10.5 0.1 2.1 3 0 0 3 3 3 0 ABC-2 family transporter protein Herpes_LMP1 PF05297.11 GAX13961.1 - 0.24 10.6 0.7 3 6.9 0.2 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3040 PF11239.8 GAX13961.1 - 0.47 10.8 4.5 1.1e+02 3.2 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) FA_desaturase PF00487.24 GAX13961.1 - 5.2 6.8 6.9 1.7 8.4 0.1 2.7 2 1 0 2 2 2 0 Fatty acid desaturase zf-RING_2 PF13639.6 GAX13962.1 - 5.8e-09 36.1 2.6 5.8e-09 36.1 2.6 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 GAX13962.1 - 1.2e-07 31.3 4.4 1.2e-07 31.3 4.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX13962.1 - 1.2e-05 25.1 0.6 1.2e-05 25.1 0.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX13962.1 - 1.6e-05 24.6 0.6 1.6e-05 24.6 0.6 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX13962.1 - 1.7e-05 24.8 0.5 1.7e-05 24.8 0.5 2.6 3 0 0 3 3 3 1 RING-type zinc-finger FANCL_C PF11793.8 GAX13962.1 - 3e-05 24.1 1.1 3e-05 24.1 1.1 2.0 2 0 0 2 2 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 GAX13962.1 - 0.00071 19.6 0.2 0.00071 19.6 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAX13962.1 - 0.0013 18.9 6.6 0.0013 18.9 6.6 3.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 GAX13962.1 - 0.0086 15.7 1.3 0.0086 15.7 1.3 2.3 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAX13962.1 - 0.023 14.7 0.8 0.023 14.7 0.8 2.8 3 0 0 3 3 3 0 zinc-RING finger domain RINGv PF12906.7 GAX13962.1 - 0.77 9.9 9.4 0.056 13.6 2.8 2.4 2 0 0 2 2 2 0 RING-variant domain Sm_multidrug_ex PF06695.11 GAX13963.1 - 7.3e-31 107.3 5.5 1.5e-30 106.3 5.5 1.6 1 0 0 1 1 1 1 Putative small multi-drug export protein NAD_binding_1 PF00175.21 GAX13963.1 - 7.4e-26 90.9 0.0 1.4e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX13963.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF2358 PF10184.9 GAX13965.1 - 0.0084 16.4 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) TRAM_LAG1_CLN8 PF03798.16 GAX13966.1 - 1.9e-16 60.4 15.6 1.9e-16 60.4 15.6 1.6 2 0 0 2 2 2 1 TLC domain 5_nucleotid_C PF02872.18 GAX13967.1 - 4e-36 124.6 0.0 1e-35 123.3 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 GAX13967.1 - 1.5e-06 28.8 0.0 2.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hat1_N PF10394.9 GAX13968.1 - 2.6e-08 34.3 0.3 0.0093 16.2 0.0 3.0 3 1 0 3 3 3 2 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 GAX13968.1 - 0.0029 17.8 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 GAX13968.1 - 0.028 14.1 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 MOZ/SAS family DrrA_P4M PF14860.6 GAX13968.1 - 0.072 12.9 0.4 0.18 11.7 0.4 1.7 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF1451 PF07295.11 GAX13968.1 - 0.15 12.1 0.2 0.15 12.1 0.2 1.9 2 1 0 2 2 2 0 Zinc-ribbon containing domain FAM176 PF14851.6 GAX13968.1 - 6.9 6.3 9.3 0.84 9.3 4.3 2.1 2 0 0 2 2 2 0 FAM176 family IF3_C PF00707.22 GAX13970.1 - 3.7e-30 103.7 0.6 8.4e-30 102.6 0.6 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 GAX13970.1 - 1.6e-23 82.8 0.2 3.8e-23 81.5 0.2 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain NOA36 PF06524.12 GAX13970.1 - 0.42 9.9 12.2 0.77 9.0 12.2 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3295 PF11702.8 GAX13970.1 - 0.92 8.8 12.4 1.6 8.0 12.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF1168 PF06658.12 GAX13970.1 - 6.7 6.5 16.7 0.22 11.3 8.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) PRP3 PF08572.10 GAX13971.1 - 1.7e-46 158.8 9.2 2.3e-46 158.3 8.1 1.9 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 GAX13971.1 - 6.5e-44 149.6 0.1 6.5e-44 149.6 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) DUF4148 PF13663.6 GAX13971.1 - 0.25 11.5 4.4 0.98 9.7 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) ADK PF00406.22 GAX13972.1 - 4.6e-18 65.8 0.0 5.6e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX13972.1 - 1.3e-09 38.6 0.0 2.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX13972.1 - 0.0069 16.6 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 GAX13972.1 - 0.034 14.3 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.6 GAX13972.1 - 0.079 13.5 0.0 0.76 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_polI_A34 PF08208.11 GAX13973.1 - 4.8e-15 56.2 24.4 9.7e-15 55.2 24.4 1.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 GAX13973.1 - 8.9 6.0 14.8 16 5.2 14.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ADK PF00406.22 GAX13974.1 - 9.7e-35 119.9 0.0 1.8e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX13974.1 - 2.9e-20 73.1 0.0 4.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX13974.1 - 9.7e-09 35.9 0.0 2.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX13974.1 - 7.4e-07 29.4 0.0 2.5e-06 27.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain EF-hand_1 PF00036.32 GAX13974.1 - 4.9e-06 25.7 0.2 1.3e-05 24.4 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GAX13974.1 - 6e-06 26.0 0.3 2.5e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 GAX13974.1 - 1e-05 25.9 0.3 2.7e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX13974.1 - 4.4e-05 23.1 0.1 0.0023 17.7 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GAX13974.1 - 0.00014 21.2 0.3 0.00031 20.1 0.3 1.5 1 0 0 1 1 1 1 EF hand Zeta_toxin PF06414.12 GAX13974.1 - 0.015 14.6 0.0 0.044 13.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 GAX13974.1 - 0.029 14.2 0.1 0.8 9.5 0.0 2.1 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 GAX13974.1 - 0.032 14.5 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAX13974.1 - 0.04 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ploopntkinase3 PF18751.1 GAX13974.1 - 0.041 13.8 0.1 0.33 10.8 0.0 2.1 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 AAA PF00004.29 GAX13974.1 - 0.055 13.9 0.1 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Flavi_NS5 PF00972.20 GAX13974.1 - 0.066 11.4 0.1 0.092 10.9 0.1 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Thymidylate_kin PF02223.17 GAX13974.1 - 0.077 12.7 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 GAX13974.1 - 0.091 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain BUD22 PF09073.10 GAX13975.1 - 9.7e-23 81.2 52.5 1.4e-10 41.1 0.1 5.0 1 1 4 5 5 5 4 BUD22 3HCDH_N PF02737.18 GAX13976.1 - 1.5e-61 207.5 0.1 1.9e-61 207.1 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAX13976.1 - 1.2e-29 102.7 0.0 2.2e-28 98.7 0.0 2.3 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAX13976.1 - 0.0015 18.8 1.2 0.0049 17.1 1.2 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAX13976.1 - 0.0055 17.3 0.2 0.011 16.3 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAX13976.1 - 0.04 13.3 0.8 0.077 12.3 0.8 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TauD PF02668.16 GAX13977.1 - 2e-29 103.2 0.0 3.3e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NYN PF01936.18 GAX13979.1 - 5.2e-13 49.7 0.0 2e-12 47.8 0.0 2.0 1 1 0 1 1 1 1 NYN domain SAP PF02037.27 GAX13979.1 - 8.1e-12 44.6 0.1 2e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 SAP domain YebO PF13974.6 GAX13979.1 - 0.74 9.9 8.6 0.13 12.4 3.5 2.2 2 0 0 2 2 2 0 YebO-like protein Cortex-I_coil PF09304.10 GAX13979.1 - 1.1 9.5 9.6 0.28 11.4 1.1 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil TPR_12 PF13424.6 GAX13980.1 - 0.013 15.8 0.6 0.13 12.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX13980.1 - 0.1 12.5 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Mito_carr PF00153.27 GAX13981.1 - 8.8e-59 195.5 2.6 7.1e-22 77.2 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein CENP-B_dimeris PF09026.10 GAX13981.1 - 0.0067 16.8 3.8 0.011 16.1 3.8 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Tim17 PF02466.19 GAX13981.1 - 9.9 6.6 8.3 2.6e+02 2.0 8.9 2.6 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family MFS_5 PF05631.14 GAX13982.1 - 1.5e-64 218.1 5.2 1.5e-64 218.1 5.2 1.4 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAX13982.1 - 2.4e-18 66.2 28.8 2.4e-18 66.2 28.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Aminotran_4 PF01063.19 GAX13983.1 - 2e-28 99.8 0.0 2.4e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV PhyH PF05721.13 GAX13984.1 - 6.3e-08 33.1 0.2 7.5e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 GAX13984.1 - 0.0007 19.5 0.0 0.33 10.7 0.0 2.5 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family DUF4462 PF14692.6 GAX13984.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Epimerase PF01370.21 GAX13985.1 - 0.0008 18.9 0.1 0.0095 15.4 0.1 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAX13985.1 - 0.083 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rab15_effector PF15208.6 GAX13985.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Rab15 effector NAD_binding_2 PF03446.15 GAX13985.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ank_2 PF12796.7 GAX13987.1 - 1.6e-43 147.2 0.0 4e-10 40.1 0.0 5.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX13987.1 - 1.6e-29 101.6 0.0 1.2e-06 28.7 0.0 7.1 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX13987.1 - 7.2e-23 80.7 0.7 0.00035 21.1 0.0 7.7 1 1 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 GAX13987.1 - 4.6e-19 67.9 0.2 0.27 11.8 0.0 9.2 10 0 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.6 GAX13987.1 - 5.5e-19 66.3 2.5 0.29 11.8 0.0 9.9 10 1 0 10 10 10 4 Ankyrin repeat SUI1 PF01253.22 GAX13987.1 - 0.0058 17.1 0.0 1.3 9.6 0.0 2.9 3 0 0 3 3 3 1 Translation initiation factor SUI1 DUF5492 PF17596.2 GAX13987.1 - 0.036 14.4 0.1 1.7 9.0 0.0 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5492) 2OG-FeII_Oxy PF03171.20 GAX13989.1 - 1.5e-09 38.2 0.2 5.9e-09 36.3 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF987 PF06174.11 GAX13989.1 - 0.6 10.1 2.8 3.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF987) OTCace_N PF02729.21 GAX13990.1 - 2.5e-41 141.1 0.0 5.9e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 GAX13990.1 - 3.2e-32 111.8 0.0 5.4e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pkinase PF00069.25 GAX13991.1 - 1.5e-05 24.5 0.8 0.00063 19.2 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Yop-YscD_cpl PF16697.5 GAX13991.1 - 0.00054 20.2 0.0 0.00096 19.4 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 GAX13991.1 - 0.0061 15.4 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 GAX13991.1 - 0.019 15.3 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 FHA domain Methyltransf_5 PF01795.19 GAX13992.1 - 9.4e-76 255.2 0.0 1.1e-75 255.0 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family LRR_6 PF13516.6 GAX13993.1 - 4.5e-08 32.5 9.8 0.11 12.6 0.2 5.5 5 0 0 5 5 5 3 Leucine Rich repeat CHAT PF12770.7 GAX13993.1 - 5e-08 32.7 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 GAX13993.1 - 1.1e-07 32.0 0.0 2.8e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAX13993.1 - 2.9e-06 27.8 0.0 1.8e-05 25.2 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX13993.1 - 0.00031 21.0 0.1 0.001 19.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain Arm PF00514.23 GAX13993.1 - 0.001 19.0 0.0 7.5 6.7 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat LRR_4 PF12799.7 GAX13993.1 - 0.065 13.7 15.7 0.73 10.4 0.8 4.7 2 1 4 6 6 6 0 Leucine Rich repeats (2 copies) NB-ARC PF00931.22 GAX13993.1 - 0.1 11.7 1.3 0.16 11.1 0.3 1.7 2 0 0 2 2 2 0 NB-ARC domain LRR_1 PF00560.33 GAX13993.1 - 0.12 13.0 11.8 70 4.6 0.2 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 GAX13993.1 - 3.8 7.3 9.6 83 3.1 0.0 4.7 3 1 0 3 3 3 0 Leucine rich repeat HMGL-like PF00682.19 GAX13994.1 - 5.9e-49 167.0 0.3 9e-49 166.4 0.3 1.3 1 0 0 1 1 1 1 HMGL-like zf-CCHC PF00098.23 GAX13996.1 - 2.5e-13 49.4 27.1 0.00035 20.5 1.5 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 GAX13996.1 - 5.9e-05 22.8 27.3 0.0062 16.3 3.4 4.3 4 0 0 4 4 4 2 Zinc knuckle zinc-ribbons_6 PF07191.12 GAX13996.1 - 0.0046 16.9 7.0 0.0046 16.9 7.0 2.9 1 1 1 2 2 2 1 zinc-ribbons zf-C2H2_10 PF16588.5 GAX13996.1 - 1.3 8.8 11.7 0.51 10.1 2.7 2.7 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 GAX13996.1 - 1.5 8.6 21.0 2.2 8.1 2.2 4.2 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 GAX13996.1 - 2.5 8.2 30.8 0.86 9.6 2.3 4.5 2 2 2 4 4 4 0 Zinc knuckle HIG_1_N PF04588.13 GAX13997.1 - 0.00013 22.1 0.1 0.00065 19.9 0.0 2.1 2 1 0 2 2 2 1 Hypoxia induced protein conserved region PPR_2 PF13041.6 GAX13998.1 - 1.7e-22 79.3 3.6 1.7e-07 31.3 0.0 6.9 4 2 2 6 6 6 4 PPR repeat family PPR_3 PF13812.6 GAX13998.1 - 6.3e-22 77.4 0.0 0.00022 21.2 0.0 5.2 5 1 0 5 5 5 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX13998.1 - 9.6e-18 63.6 0.0 0.024 14.3 0.0 8.0 8 1 1 9 9 9 4 PPR repeat PPR_long PF17177.4 GAX13998.1 - 4e-07 29.6 11.2 6.8e-05 22.3 5.0 3.1 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX13998.1 - 7.3e-07 29.0 14.5 1.3 9.4 0.0 8.5 10 0 0 10 10 10 3 PPR repeat FTCD_C PF04961.12 GAX13998.1 - 0.0034 17.2 5.4 0.38 10.5 0.4 3.5 1 1 2 4 4 4 2 Formiminotransferase-cyclodeaminase Vps54_N PF10475.9 GAX13998.1 - 0.0095 15.3 0.7 1.2 8.4 0.0 3.1 1 1 1 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Vps39_1 PF10366.9 GAX13998.1 - 0.085 13.1 1.5 24 5.2 0.1 3.4 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 1 RhoGAP PF00620.27 GAX13998.1 - 0.13 12.1 0.9 12 5.7 0.2 2.8 2 0 0 2 2 2 0 RhoGAP domain Fez1 PF06818.15 GAX13999.1 - 0.11 13.0 0.3 0.11 13.0 0.3 4.5 1 1 3 4 4 4 0 Fez1 Surfac_D-trimer PF09006.11 GAX13999.1 - 0.16 11.9 2.0 30 4.6 0.2 3.8 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DBD_HTH PF18430.1 GAX13999.1 - 0.26 11.1 3.7 0.17 11.7 0.4 2.5 3 0 0 3 3 3 0 Putative DNA-binding domain Mss4 PF04421.13 GAX13999.1 - 4.8 7.4 7.1 0.89 9.7 0.2 3.4 2 1 1 3 3 3 0 Mss4 protein Ribosomal_L5_C PF00673.21 GAX14000.1 - 4.8e-22 78.0 0.1 1.1e-21 76.7 0.1 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAX14000.1 - 1.1e-21 76.9 0.0 4.8e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 GAX14000.1 - 0.05 13.3 0.8 0.091 12.5 0.2 1.7 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain PseudoU_synth_2 PF00849.22 GAX14002.1 - 1.6e-13 51.1 0.2 9.6e-13 48.5 0.2 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 GAX14002.1 - 8.7e-05 22.2 0.1 0.0002 21.0 0.1 1.7 1 0 0 1 1 1 1 S4 domain DUF1062 PF06353.12 GAX14002.1 - 0.1 13.4 0.0 0.37 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) BTB PF00651.31 GAX14003.1 - 2.9e-14 53.2 0.4 5.3e-13 49.2 0.2 2.8 2 1 0 2 2 2 1 BTB/POZ domain HTH_Tnp_ISL3 PF13542.6 GAX14003.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2634 PF10934.8 GAX14003.1 - 0.31 11.2 2.6 1.6 8.8 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2634) UTP25 PF06862.12 GAX14004.1 - 1.1e-138 462.9 0.0 2e-138 462.2 0.0 1.4 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AMP-binding PF00501.28 GAX14005.1 - 2.5e-94 316.3 0.0 3.4e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF819 PF05684.12 GAX14006.1 - 2.8e-37 128.7 21.3 6.4e-37 127.5 21.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF819) MMR_HSR1 PF01926.23 GAX14007.1 - 0.00024 21.2 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_M11 PF05548.11 GAX14009.1 - 2.3e-11 43.4 2.7 4e-10 39.3 2.7 2.1 1 1 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_5 PF13688.6 GAX14009.1 - 0.00095 19.4 0.1 0.0018 18.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Metallopep PF12044.8 GAX14009.1 - 0.0057 15.3 0.3 0.01 14.4 0.3 1.3 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M10 PF00413.24 GAX14009.1 - 0.0059 16.5 0.7 0.012 15.5 0.7 1.5 1 1 0 1 1 1 1 Matrixin Peptidase_M54 PF07998.11 GAX14009.1 - 0.014 15.4 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M54 DUF4953 PF16313.5 GAX14009.1 - 0.016 14.5 0.4 0.027 13.7 0.4 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 GAX14009.1 - 0.02 15.4 0.9 0.098 13.2 0.4 2.5 1 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX14009.1 - 0.022 14.4 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 GAX14009.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) AAA_11 PF13086.6 GAX14013.1 - 8.1e-68 229.0 0.0 8.1e-68 229.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 GAX14013.1 - 3e-57 193.5 0.0 5.1e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX14013.1 - 7.7e-09 35.5 0.5 0.0015 18.3 0.2 2.9 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAX14013.1 - 5.4e-08 33.3 1.2 2e-06 28.2 0.2 3.1 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAX14013.1 - 2.2e-06 27.6 0.2 0.41 10.3 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAX14013.1 - 5.5e-06 26.7 0.3 0.00025 21.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain WW PF00397.26 GAX14013.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 WW domain AAA PF00004.29 GAX14013.1 - 0.0025 18.2 0.1 0.012 16.0 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX14013.1 - 0.0027 18.1 1.4 0.019 15.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain ResIII PF04851.15 GAX14013.1 - 0.0079 16.2 0.1 1.2 9.1 0.1 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 GAX14013.1 - 0.01 15.1 0.1 0.36 10.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 GAX14013.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 GAX14013.1 - 0.035 13.6 0.7 1.5 8.3 0.1 2.9 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Rad17 PF03215.15 GAX14013.1 - 0.036 14.0 0.1 0.68 9.8 0.0 2.7 2 1 1 3 3 3 0 Rad17 P-loop domain AAA_29 PF13555.6 GAX14013.1 - 0.094 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain WW PF00397.26 GAX14014.1 - 0.00061 19.8 0.5 0.0011 19.0 0.5 1.5 1 0 0 1 1 1 1 WW domain BacteriocIIc_cy PF12173.8 GAX14014.1 - 0.21 11.9 3.0 0.37 11.1 3.0 1.4 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like GCS2 PF04107.13 GAX14014.1 - 0.82 9.0 0.0 0.82 9.0 0.0 1.8 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) AAA PF00004.29 GAX14015.1 - 1.2e-38 132.6 0.0 2.1e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX14015.1 - 2.2e-13 49.8 0.1 4e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX14015.1 - 1.7e-05 25.2 0.0 0.024 15.0 0.1 3.1 3 1 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 GAX14015.1 - 0.00032 20.7 0.0 0.0014 18.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX14015.1 - 0.0012 19.2 0.2 0.11 12.7 0.1 2.9 2 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 GAX14015.1 - 0.003 17.3 0.0 0.0087 15.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain FtsH_ext PF06480.15 GAX14015.1 - 0.0035 17.7 0.0 0.012 16.0 0.0 2.0 1 1 0 1 1 1 1 FtsH Extracellular Mg_chelatase PF01078.21 GAX14015.1 - 0.0061 16.0 0.3 0.015 14.7 0.2 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAX14015.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 GAX14015.1 - 0.021 14.7 0.5 0.26 11.2 0.1 2.7 2 1 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 GAX14015.1 - 0.026 14.3 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAX14015.1 - 0.051 13.6 0.0 7.1 6.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX14015.1 - 0.063 13.4 0.3 0.21 11.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 GAX14015.1 - 0.074 13.0 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 GAX14015.1 - 0.11 11.6 0.0 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 GAX14015.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 GAX14015.1 - 0.21 12.1 0.1 0.57 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain SNF2_N PF00176.23 GAX14016.1 - 6.5e-45 153.4 0.1 1.2e-44 152.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CW PF07496.15 GAX14016.1 - 1.7e-13 50.3 7.4 1.7e-13 50.3 7.4 2.4 2 0 0 2 2 2 1 CW-type Zinc Finger Helicase_C PF00271.31 GAX14016.1 - 6.2e-13 49.1 0.0 2.3e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX14016.1 - 1.9e-06 27.8 0.0 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAX14016.1 - 1.8e-05 24.8 0.0 6.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CCDC-167 PF15188.6 GAX14016.1 - 4.2 7.8 8.8 2.1 8.8 5.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 RTC_insert PF05189.13 GAX14017.1 - 3e-26 91.9 0.1 4.3e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 GAX14017.1 - 2.8e-22 79.0 0.0 3.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RRM_1 PF00076.22 GAX14018.1 - 9.6e-14 51.0 0.0 2.2e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1b PF00579.25 GAX14019.1 - 1.6e-48 165.5 0.0 7.2e-43 147.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Pkinase PF00069.25 GAX14020.1 - 2.7e-36 125.3 0.0 2.9e-35 121.9 0.0 2.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14020.1 - 1.8e-14 53.6 0.1 3.8e-09 36.2 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.23 GAX14020.1 - 2.4e-06 27.6 0.3 6.1e-06 26.3 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX14020.1 - 0.0017 18.0 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAX14020.1 - 0.0081 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX14020.1 - 0.025 13.9 0.0 0.091 12.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 GAX14020.1 - 0.048 12.4 0.0 0.048 12.4 0.0 1.8 2 1 1 3 3 3 0 Fungal protein kinase SR-25 PF10500.9 GAX14020.1 - 0.19 11.3 4.2 0.29 10.7 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DnaJ PF00226.31 GAX14021.1 - 1.2e-16 60.5 0.1 5e-16 58.6 0.1 2.2 1 0 0 1 1 1 1 DnaJ domain PPR PF01535.20 GAX14022.1 - 0.035 14.3 1.8 13 6.3 0.0 5.1 4 1 0 4 4 4 0 PPR repeat COBRA PF04833.15 GAX14022.1 - 0.12 12.2 0.1 2.5 8.0 0.1 2.4 2 1 0 2 2 2 0 COBRA-like protein DUF3323 PF11796.8 GAX14022.1 - 0.18 11.6 2.5 0.35 10.7 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) PFEMP PF03011.15 GAX14022.1 - 0.33 11.6 3.4 1.4 9.6 0.1 2.9 3 0 0 3 3 3 0 PFEMP DBL domain TPR_14 PF13428.6 GAX14022.1 - 0.63 11.0 5.9 2.4 9.2 0.3 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Peptidase_M48_N PF16491.5 GAX14023.1 - 7.6e-63 211.7 6.2 7.6e-63 211.7 6.2 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 GAX14023.1 - 7.9e-50 169.4 0.0 1.3e-49 168.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 GAX14023.1 - 0.00032 20.0 0.1 0.00076 18.8 0.0 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 5TM-5TMR_LYT PF07694.12 GAX14023.1 - 0.0076 15.8 0.1 0.022 14.3 0.1 1.8 1 0 0 1 1 1 1 5TMR of 5TMR-LYT ING PF12998.7 GAX14023.1 - 0.077 13.6 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding MCM PF00493.23 GAX14025.1 - 2.9e-99 330.7 0.0 4e-99 330.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX14025.1 - 1.1e-38 131.9 0.8 2.2e-38 131.0 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX14025.1 - 1.6e-25 89.3 1.2 4.1e-25 88.0 1.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 GAX14025.1 - 2.8e-20 72.6 0.3 7.5e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 GAX14025.1 - 4.2e-08 33.7 3.5 3.8e-07 30.6 3.6 2.4 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAX14025.1 - 9.7e-07 28.4 0.0 2.6e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX14025.1 - 5.5e-05 23.2 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAX14025.1 - 0.00043 20.0 0.0 0.0012 18.6 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAX14025.1 - 0.0038 17.1 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HypA PF01155.19 GAX14025.1 - 0.088 12.8 0.1 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CBM_6 PF03422.15 GAX14026.1 - 1.6e-73 244.9 4.8 2.8e-13 50.2 0.5 7.5 8 0 0 8 8 8 7 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX14026.1 - 6.8e-25 87.4 0.1 0.00059 19.9 0.0 7.1 7 0 0 7 7 7 6 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX14026.1 - 8.7e-16 58.3 7.8 0.039 14.2 0.0 7.6 7 0 0 7 7 7 6 Carbohydrate binding module (family 35) DUF5397 PF17375.2 GAX14026.1 - 0.0011 18.6 0.1 1.2 8.9 0.0 5.0 5 0 0 5 5 5 1 Family of unknown function (DUF5397) Iron_transport PF10634.9 GAX14026.1 - 0.0067 16.6 0.0 1.1e+02 2.9 0.0 5.1 6 0 0 6 6 6 0 Fe2+ transport protein Roughex PF06020.11 GAX14026.1 - 0.056 12.5 0.0 26 3.7 0.0 3.8 4 0 0 4 4 4 0 Drosophila roughex protein CBM_6 PF03422.15 GAX14027.1 - 2e-29 102.4 0.0 2.2e-12 47.4 0.0 3.9 4 0 0 4 4 4 3 Carbohydrate binding module (family 6) CBM_35 PF16990.5 GAX14027.1 - 2.5e-09 37.4 0.1 0.064 13.5 0.0 3.6 3 1 0 3 3 3 3 Carbohydrate binding module (family 35) DUF5010_C PF18099.1 GAX14027.1 - 4.3e-07 30.1 0.0 0.014 15.5 0.0 3.2 3 0 0 3 3 3 2 DUF5010 C-terminal domain DUF5397 PF17375.2 GAX14027.1 - 1.2e-05 25.0 0.0 0.11 12.2 0.0 3.3 3 0 0 3 3 3 2 Family of unknown function (DUF5397) TPR_12 PF13424.6 GAX14028.1 - 9e-06 25.9 0.0 0.073 13.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX14028.1 - 6e-05 22.7 2.0 0.062 13.2 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14028.1 - 0.00031 20.6 0.3 0.66 10.2 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX14028.1 - 0.0052 16.4 0.2 0.017 14.8 0.2 1.9 1 0 0 1 1 1 1 TPR repeat TPR_15 PF13429.6 GAX14028.1 - 0.02 14.1 0.5 0.1 11.8 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX14028.1 - 0.06 13.4 0.3 7.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX14028.1 - 0.1 12.9 3.8 17 5.7 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAX14028.1 - 0.1 13.3 0.0 0.78 10.4 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX14028.1 - 4.4 8.2 6.2 15 6.5 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat FMN_dh PF01070.18 GAX14029.1 - 2.5e-113 378.6 0.1 3e-113 378.4 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 GAX14029.1 - 3.6e-11 42.7 1.2 5e-09 35.6 0.4 2.8 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 GAX14029.1 - 4.5e-08 32.6 0.1 0.0019 17.4 0.1 2.3 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 GAX14029.1 - 1.3e-07 31.1 0.4 9e-06 25.1 0.1 2.2 1 1 1 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 GAX14029.1 - 1.5e-05 24.5 2.4 2.4e-05 23.9 2.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 GAX14029.1 - 2.1e-05 23.9 2.7 0.044 13.1 0.2 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAX14029.1 - 0.0055 16.2 0.2 0.029 13.8 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 GAX14029.1 - 0.017 14.5 0.0 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator TGT PF01702.18 GAX14029.1 - 0.16 11.1 0.0 0.5 9.5 0.0 1.7 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase CBM_6 PF03422.15 GAX14030.1 - 6.3e-34 117.0 4.6 2e-11 44.3 0.1 3.3 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX14030.1 - 1.1e-23 83.5 2.7 1.6e-07 31.4 0.0 3.4 3 1 0 3 3 3 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX14030.1 - 3.2e-05 24.2 3.4 0.079 13.2 0.4 3.5 3 0 0 3 3 3 2 Carbohydrate binding module (family 35) DUF4761 PF15958.5 GAX14030.1 - 0.047 13.8 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) WD40 PF00400.32 GAX14031.1 - 5.9e-10 39.6 4.4 0.26 12.2 0.0 6.5 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX14031.1 - 1.8e-07 31.4 0.5 0.0054 17.0 0.0 4.2 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 GAX14031.1 - 0.00058 19.9 1.4 0.001 19.1 1.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 GAX14031.1 - 0.004 17.4 2.0 0.0081 16.4 2.0 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family HOOK PF05622.12 GAX14031.1 - 0.013 13.7 1.1 0.018 13.2 1.1 1.1 1 0 0 1 1 1 0 HOOK protein Cep57_CLD_2 PF14197.6 GAX14031.1 - 0.028 14.5 0.7 0.049 13.7 0.7 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 GAX14031.1 - 0.051 13.6 0.6 0.079 13.0 0.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 GAX14031.1 - 0.13 12.4 4.4 0.25 11.4 3.9 1.7 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 GAX14031.1 - 0.15 11.8 3.7 0.41 10.4 1.9 2.1 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.18 GAX14031.1 - 0.16 12.3 0.6 0.51 10.6 0.5 1.8 1 1 1 2 2 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 GAX14031.1 - 0.21 11.5 1.2 0.39 10.6 1.2 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 GAX14031.1 - 0.24 12.1 0.9 0.45 11.2 0.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 GAX14031.1 - 0.35 11.3 3.1 0.6 10.6 3.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Aldo_ket_red PF00248.21 GAX14032.1 - 5e-43 147.4 0.0 9.9e-35 120.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family HSF_DNA-bind PF00447.17 GAX14033.1 - 0.0017 18.9 0.1 0.0035 17.9 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding ANF_receptor PF01094.28 GAX14034.1 - 5.8e-22 78.3 0.0 1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 GAX14034.1 - 1.2e-13 50.9 0.1 5.4e-11 42.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Peripla_BP_6 PF13458.6 GAX14034.1 - 9.9e-12 45.2 0.3 3e-11 43.6 0.2 1.7 2 0 0 2 2 2 1 Periplasmic binding protein Pkinase PF00069.25 GAX14034.1 - 2.8e-09 36.7 0.2 2e-06 27.4 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain DUF732 PF05305.14 GAX14034.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF732) ANF_receptor PF01094.28 GAX14035.1 - 3e-22 79.2 0.0 5.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 GAX14035.1 - 4.6e-14 52.8 0.1 2.8e-13 50.3 0.2 1.9 2 0 0 2 2 2 1 Periplasmic binding protein Pkinase_Tyr PF07714.17 GAX14035.1 - 9.4e-08 31.6 0.0 9.2e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAX14035.1 - 2.3e-05 23.9 0.0 0.004 16.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain LepA_C PF06421.12 GAX14036.1 - 1.4e-36 124.9 2.1 2.8e-36 123.9 2.1 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 GAX14036.1 - 9.6e-33 113.4 0.0 1.9e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX14036.1 - 2.3e-11 43.6 0.0 5.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus YIF1 PF03878.15 GAX14037.1 - 4.5e-52 176.9 4.5 4.5e-52 176.9 4.5 1.4 2 0 0 2 2 2 1 YIF1 Dot_icm_IcmQ PF09475.10 GAX14038.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Rieske PF00355.26 GAX14039.1 - 0.0033 17.3 0.1 0.0046 16.9 0.1 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Aldo_ket_red PF00248.21 GAX14040.1 - 6.8e-34 117.4 0.0 1e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family TauD PF02668.16 GAX14040.1 - 4e-26 92.4 0.7 2.2e-25 90.0 0.7 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_C2 PF00648.21 GAX14041.1 - 2.2e-60 204.2 0.1 1.5e-59 201.5 0.0 2.2 2 1 0 2 2 2 1 Calpain family cysteine protease zf-GRF PF06839.12 GAX14041.1 - 2.6e-06 27.4 6.0 0.00092 19.3 1.3 2.9 2 0 0 2 2 2 2 GRF zinc finger Glyco_hydro_30C PF17189.4 GAX14041.1 - 0.032 14.5 0.0 0.096 12.9 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain UBA_4 PF14555.6 GAX14041.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Ferrochelatase PF00762.19 GAX14042.1 - 4.9e-110 367.5 0.0 6e-110 367.2 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 GAX14042.1 - 0.00072 19.8 0.0 0.026 14.8 0.0 2.7 2 0 0 2 2 2 1 CbiX Methyltrans_SAM PF10672.9 GAX14043.1 - 9.4e-14 51.2 0.0 1.6e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase MTS PF05175.14 GAX14043.1 - 1.8e-09 37.4 0.1 3e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PUA_3 PF17785.1 GAX14043.1 - 8.2e-08 31.9 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain Methyltransf_31 PF13847.6 GAX14043.1 - 8.7e-08 32.1 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX14043.1 - 1.4e-07 31.3 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 GAX14043.1 - 4.9e-07 30.4 0.3 1.3e-06 29.0 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 GAX14043.1 - 7e-07 29.1 0.6 5.8e-06 26.1 0.6 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PrmA PF06325.13 GAX14043.1 - 5.1e-06 26.1 0.1 7.3e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 GAX14043.1 - 1e-05 25.8 0.2 1.6e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 GAX14043.1 - 3.6e-05 23.7 0.6 0.00012 22.1 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 GAX14043.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 GAX14043.1 - 0.023 15.4 0.1 0.059 14.0 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAX14043.1 - 0.037 13.9 0.0 0.092 12.6 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain Cystatin PF00031.21 GAX14044.1 - 0.00013 22.2 0.6 0.00082 19.6 0.6 2.0 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 GAX14044.1 - 0.0022 18.3 0.1 0.0036 17.6 0.1 1.3 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor AOX PF01786.17 GAX14045.1 - 7.1e-74 248.0 0.1 1e-73 247.5 0.1 1.2 1 0 0 1 1 1 1 Alternative oxidase EF-hand_5 PF13202.6 GAX14045.1 - 4.7e-05 22.7 0.2 0.0001 21.6 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GAX14045.1 - 0.00023 20.5 0.0 0.00062 19.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAX14045.1 - 0.00058 20.3 0.2 0.0015 19.0 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX14045.1 - 0.00075 19.2 0.1 0.0028 17.5 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 GAX14045.1 - 0.023 14.5 0.1 0.9 9.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair POT1 PF02765.17 GAX14046.1 - 1.5e-14 54.0 0.0 3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 GAX14046.1 - 0.00029 20.8 0.0 0.0017 18.3 0.0 2.2 2 1 0 2 2 2 1 ssDNA-binding domain of telomere protection protein Proteasome PF00227.26 GAX14047.1 - 5.1e-31 107.6 0.2 8.4e-31 106.9 0.2 1.3 1 1 0 1 1 1 1 Proteasome subunit Peptidase_C12 PF01088.21 GAX14048.1 - 4.1e-55 186.8 0.0 4.8e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ArnB_C PF18677.1 GAX14048.1 - 0.063 13.4 0.7 0.099 12.8 0.7 1.3 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Pkinase PF00069.25 GAX14050.1 - 5e-34 117.9 0.0 3.8e-22 78.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ribonuc_2-5A PF06479.12 GAX14050.1 - 1.1e-33 116.1 0.3 2e-33 115.3 0.3 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 GAX14050.1 - 2.5e-17 63.0 0.0 1.4e-12 47.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.6 GAX14050.1 - 0.00015 21.4 0.8 0.0008 19.1 1.0 2.1 2 0 0 2 2 2 1 PQQ-like domain Kdo PF06293.14 GAX14050.1 - 0.00083 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX14050.1 - 0.029 13.1 0.1 0.22 10.3 0.2 2.1 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 GAX14050.1 - 0.049 13.5 0.3 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family PQQ PF01011.21 GAX14050.1 - 0.054 13.4 0.0 7.2 6.7 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat PAPS_reduct PF01507.19 GAX14052.1 - 1.7e-23 83.6 0.1 2.5e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PAPS_reduct PF01507.19 GAX14053.1 - 2.9e-38 131.6 0.0 4.2e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 GAX14053.1 - 5.8e-12 45.5 0.0 1.5e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX14053.1 - 0.014 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.6 GAX14053.1 - 0.047 13.5 0.2 0.23 11.3 0.2 1.9 1 1 0 1 1 1 0 F plasmid transfer operon protein PI31_Prot_N PF11566.8 GAX14054.1 - 2.1e-06 27.6 0.0 4.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal Nefa_Nip30_N PF10187.9 GAX14054.1 - 0.0093 16.3 1.9 0.019 15.3 1.9 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 EF-hand_7 PF13499.6 GAX14055.1 - 0.068 13.6 0.0 3.1 8.3 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain pair Glyoxalase_3 PF13468.6 GAX14056.1 - 8e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Ank_2 PF12796.7 GAX14057.1 - 2e-27 95.6 0.2 2.3e-12 47.3 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX14057.1 - 2e-26 92.0 2.6 7.7e-08 32.7 0.0 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX14057.1 - 2.5e-23 79.6 1.2 6.2e-05 23.1 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 GAX14057.1 - 1.4e-16 60.3 1.1 1.2e-05 25.5 0.1 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX14057.1 - 3e-13 49.5 5.1 0.00013 22.2 0.1 5.4 7 0 0 7 7 7 3 Ankyrin repeat Proteasome PF00227.26 GAX14058.1 - 2e-09 37.2 0.0 1.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Proteasome subunit Arm PF00514.23 GAX14059.1 - 1.1e-11 44.4 0.2 0.00017 21.5 0.0 2.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 GAX14059.1 - 5.2e-06 25.9 0.2 1.2e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Atypical Arm repeat Mo25 PF08569.11 GAX14059.1 - 0.051 13.0 0.1 0.77 9.1 0.0 2.2 2 1 0 2 2 2 0 Mo25-like Lem_TRP PF08262.11 GAX14060.1 - 6.7 7.0 6.7 23 5.3 0.4 3.3 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide TrwB_AAD_bind PF10412.9 GAX14061.1 - 0.065 12.1 0.1 0.072 12.0 0.1 1.0 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arm PF00514.23 GAX14063.1 - 2.4e-23 81.4 2.4 2.6e-10 40.0 0.1 3.5 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 GAX14063.1 - 3.5e-06 26.5 0.4 7.6e-06 25.4 0.4 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 GAX14063.1 - 2.2e-05 24.7 0.0 0.067 13.6 0.0 2.3 2 0 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 GAX14063.1 - 5.3e-05 23.6 0.0 0.0011 19.4 0.0 2.4 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 GAX14063.1 - 0.0001 22.3 0.4 0.0049 17.0 0.0 3.3 3 1 1 4 4 4 1 HEAT repeat Mo25 PF08569.11 GAX14063.1 - 0.024 14.0 0.1 0.12 11.8 0.1 1.9 1 1 1 2 2 2 0 Mo25-like Thioredoxin PF00085.20 GAX14064.1 - 9.9e-22 76.9 0.1 2.9e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX14064.1 - 7.1e-05 23.2 0.1 0.00032 21.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX14064.1 - 0.0071 16.7 0.4 0.04 14.3 0.0 2.4 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GAX14064.1 - 0.012 15.8 0.0 0.072 13.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 GAX14064.1 - 0.041 13.8 0.8 0.11 12.4 0.1 2.1 2 1 0 2 2 2 0 AhpC/TSA family DUF932 PF06067.11 GAX14064.1 - 0.05 13.4 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Redoxin PF08534.10 GAX14064.1 - 0.091 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Redoxin GDA1_CD39 PF01150.17 GAX14065.1 - 6e-56 189.9 0.0 1.1e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Cpn60_TCP1 PF00118.24 GAX14067.1 - 3.4e-149 497.6 7.3 4.1e-149 497.4 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-CXXC PF02008.20 GAX14068.1 - 4.3e-12 45.9 98.0 0.00019 21.4 12.3 5.8 5 0 0 5 5 5 5 CXXC zinc finger domain Pkinase PF00069.25 GAX14069.1 - 2.8e-45 154.8 0.0 7.3e-45 153.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14069.1 - 7.5e-22 77.8 0.3 1.5e-21 76.9 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_12 PF13424.6 GAX14069.1 - 9.5e-06 25.8 2.2 3.2e-05 24.2 2.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14069.1 - 1.1e-05 25.2 0.3 0.17 12.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 GAX14069.1 - 1.4e-05 24.0 0.4 3e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAX14069.1 - 8e-05 22.7 0.4 8e-05 22.7 0.4 2.3 2 1 1 3 3 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX14069.1 - 0.0005 19.5 0.0 0.0021 17.4 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAX14069.1 - 0.0013 18.2 1.4 0.0028 17.0 1.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 GAX14069.1 - 0.0016 18.2 0.5 0.57 10.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Hydin_ADK PF17213.3 GAX14069.1 - 0.0092 16.3 2.0 0.021 15.1 2.0 1.7 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain RIO1 PF01163.22 GAX14069.1 - 0.0099 15.5 6.2 0.011 15.3 0.5 2.5 1 1 1 2 2 2 1 RIO1 family HupH_C PF04809.13 GAX14069.1 - 0.016 14.9 0.1 0.096 12.4 0.0 2.1 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region TPR_19 PF14559.6 GAX14069.1 - 0.018 15.5 2.3 3.9 8.0 0.3 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat FTA2 PF13095.6 GAX14069.1 - 0.042 13.5 0.4 0.71 9.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 GAX14069.1 - 0.045 13.3 5.3 0.035 13.7 3.6 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 GAX14069.1 - 0.057 12.4 4.5 0.12 11.3 4.2 1.6 1 1 0 1 1 1 0 Haspin like kinase domain TPR_7 PF13176.6 GAX14069.1 - 0.097 12.7 2.9 1.6 8.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 GAX14069.1 - 0.21 11.7 1.5 0.86 9.7 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 GAX14069.1 - 0.31 11.7 1.9 4.7 8.0 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CMD PF02627.20 GAX14070.1 - 0.0087 16.1 0.2 0.049 13.7 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Ssu72 PF04722.13 GAX14071.1 - 4e-61 205.9 0.0 4.6e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF1651 PF07864.11 GAX14072.1 - 0.049 14.0 0.7 2.7 8.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1651) NosL PF05573.12 GAX14073.1 - 0.16 12.3 0.2 1.3 9.4 0.2 2.0 1 1 0 1 1 1 0 NosL Cullin PF00888.22 GAX14074.1 - 7.4e-84 282.5 0.4 7.5e-76 256.1 0.0 2.3 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 GAX14074.1 - 4.7e-21 74.6 1.7 2.4e-20 72.3 1.2 2.6 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF1366 PF07104.11 GAX14074.1 - 0.15 11.7 2.5 11 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) bZIP_1 PF00170.21 GAX14075.1 - 0.00013 22.0 9.2 0.00013 22.0 9.2 3.0 3 1 1 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 GAX14075.1 - 0.00054 20.0 5.5 0.00054 20.0 5.5 3.9 5 0 0 5 5 5 2 Basic region leucine zipper DUF3347 PF11827.8 GAX14075.1 - 0.014 15.6 3.4 0.022 15.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) bZIP_Maf PF03131.17 GAX14075.1 - 0.037 14.5 8.8 0.037 14.5 8.8 2.3 2 2 0 2 2 2 0 bZIP Maf transcription factor DUF3492 PF11997.8 GAX14075.1 - 0.11 12.3 0.9 0.14 11.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) LsmAD PF06741.13 GAX14075.1 - 0.11 13.1 0.9 0.11 13.1 0.9 2.1 2 0 0 2 2 2 0 LsmAD domain RRP7 PF12923.7 GAX14075.1 - 0.16 12.1 2.8 0.14 12.3 1.6 1.6 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PI3K_P85_iSH2 PF16454.5 GAX14075.1 - 0.31 10.6 7.0 0.1 12.2 4.4 1.6 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Enkurin PF13864.6 GAX14075.1 - 0.44 11.0 5.8 0.27 11.7 3.2 1.9 1 1 1 2 2 2 0 Calmodulin-binding NIF PF03031.18 GAX14077.1 - 2.2e-52 176.9 0.0 3.1e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HIG_1_N PF04588.13 GAX14078.1 - 2.9e-19 69.0 0.3 4e-19 68.6 0.3 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Beta_elim_lyase PF01212.21 GAX14079.1 - 1.2e-83 280.8 0.0 1.5e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase NSP16 PF06460.12 GAX14079.1 - 0.072 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 DegT_DnrJ_EryC1 PF01041.17 GAX14079.1 - 0.15 11.3 0.2 0.69 9.1 0.2 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CBFD_NFYB_HMF PF00808.23 GAX14080.1 - 4.1e-17 62.2 1.8 3.5e-12 46.4 0.3 2.4 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX14080.1 - 4.5e-11 43.2 4.2 1.5e-10 41.6 4.2 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAX14080.1 - 0.011 15.8 2.4 0.027 14.6 0.2 2.4 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) CENP-X PF09415.10 GAX14080.1 - 0.051 13.9 1.5 0.057 13.8 0.2 1.7 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Auxin_canalis PF05703.11 GAX14080.1 - 0.076 12.9 1.1 0.13 12.2 1.1 1.3 1 0 0 1 1 1 0 Auxin canalisation Anti-TRAP PF15777.5 GAX14081.1 - 0.11 12.5 5.8 0.34 10.9 5.9 1.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_CXXCXGXG PF00684.19 GAX14081.1 - 0.14 12.6 14.1 0.054 13.9 10.8 2.0 2 0 0 2 2 2 0 DnaJ central domain Zn_Tnp_IS1595 PF12760.7 GAX14081.1 - 6.4 6.8 7.4 37 4.4 7.8 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Calreticulin PF00262.18 GAX14083.1 - 4.3e-87 292.4 11.9 1.7e-63 214.7 2.2 2.1 1 1 1 2 2 2 2 Calreticulin family Ribosomal_L14 PF00238.19 GAX14084.1 - 5.5e-34 116.9 0.2 7.3e-34 116.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e AOX PF01786.17 GAX14085.1 - 5.1e-25 88.3 1.0 8.1e-25 87.7 1.0 1.3 1 0 0 1 1 1 1 Alternative oxidase YebO PF13974.6 GAX14085.1 - 0.26 11.4 1.3 0.59 10.2 1.3 1.5 1 0 0 1 1 1 0 YebO-like protein HrpA_pilin PF09589.10 GAX14085.1 - 2.6 8.8 5.4 0.78 10.5 0.4 2.2 2 0 0 2 2 2 0 HrpA pilus formation protein TolA_bind_tri PF16331.5 GAX14085.1 - 3.1 7.9 7.2 8.4 6.6 0.8 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF4116 PF13475.6 GAX14086.1 - 4.5e-25 87.1 2.7 8.5e-05 22.2 0.1 10.3 9 2 3 12 12 12 7 Domain of unknown function (DUF4116) Arm-DNA-bind_5 PF17293.2 GAX14086.1 - 0.41 11.1 3.0 0.61 10.6 1.9 1.9 2 0 0 2 2 2 0 Arm DNA-binding domain Methyltransf_15 PF09445.10 GAX14088.1 - 3.6e-24 85.2 0.0 1.5e-22 79.9 0.0 2.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 GAX14088.1 - 4.4e-05 23.2 0.1 0.0041 16.8 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 GAX14088.1 - 0.00034 21.2 0.0 0.00096 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX14088.1 - 0.0022 17.4 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 GAX14088.1 - 0.0024 16.9 0.1 1.1 8.2 0.0 2.6 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAX14088.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GAX14088.1 - 0.056 13.1 0.5 1.2 8.8 0.4 2.7 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 M60-like_N PF17291.2 GAX14088.1 - 0.085 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases Fucose_iso_N2 PF07882.12 GAX14088.1 - 0.17 11.4 0.0 0.48 10.0 0.0 1.5 1 1 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Methyltrans_SAM PF10672.9 GAX14088.1 - 0.18 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Homeobox_KN PF05920.11 GAX14089.1 - 3e-10 39.8 0.0 9.2e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAX14089.1 - 0.00018 21.3 0.5 0.00064 19.5 0.3 2.1 2 0 0 2 2 2 1 Homeodomain LtuB PF17455.2 GAX14090.1 - 0.97 10.1 4.7 0.22 12.1 0.5 2.1 2 1 1 3 3 3 0 Late transcription unit B FAD_binding_4 PF01565.23 GAX14091.1 - 2.9e-21 75.7 0.4 7.6e-21 74.3 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 GAX14091.1 - 8.4e-20 71.7 3.2 1.6e-10 41.3 0.0 2.4 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase DUF547 PF04784.14 GAX14092.1 - 1.5e-24 86.3 0.0 2.9e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 PH PF00169.29 GAX14092.1 - 1.1e-06 29.1 0.0 4e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 PH domain Peptidase_U32_C PF16325.5 GAX14092.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain Rieske PF00355.26 GAX14094.1 - 7.6e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 GAX14094.1 - 2.9e-10 40.5 0.3 5.5e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region HSP70 PF00012.20 GAX14095.1 - 9.6e-89 298.2 0.1 8.7e-88 295.0 0.1 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX14095.1 - 8.9e-15 54.3 0.1 1.4e-10 40.5 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein BcrAD_BadFG PF01869.20 GAX14095.1 - 5.3e-06 26.1 0.1 0.0001 21.9 0.0 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 GAX14095.1 - 0.019 14.0 0.1 0.78 8.7 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain RFC1 PF08519.12 GAX14095.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain StbA PF06406.11 GAX14095.1 - 0.044 13.0 0.1 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 StbA protein Histidinol_dh PF00815.20 GAX14095.1 - 0.05 12.6 0.1 0.081 11.9 0.1 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase CDC45 PF02724.14 GAX14096.1 - 0.91 7.7 8.7 1.1 7.4 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1943 PF09172.11 GAX14096.1 - 1.3 8.2 4.8 1.6 7.8 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) TPR_6 PF13174.6 GAX14096.1 - 1.4 9.7 5.6 0.41 11.4 0.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4604 PF15377.6 GAX14096.1 - 4.5 7.7 20.4 8.3 6.8 20.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Hydrolase_4 PF12146.8 GAX14097.1 - 1e-31 110.1 0.0 3.5e-31 108.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX14097.1 - 4.9e-12 46.9 0.2 6e-12 46.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX14097.1 - 3.4e-08 33.5 0.0 3.9e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX14097.1 - 8.4e-05 22.1 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAX14097.1 - 0.00016 21.4 0.0 0.00063 19.4 0.0 1.9 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 GAX14097.1 - 0.00061 19.7 0.1 0.31 10.8 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 GAX14097.1 - 0.041 14.0 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_3 PF07859.13 GAX14097.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Aminotran_4 PF01063.19 GAX14098.1 - 0.066 13.1 0.1 0.24 11.2 0.0 1.9 2 1 0 2 2 2 0 Amino-transferase class IV DUF1033 PF06279.11 GAX14098.1 - 0.08 13.1 0.6 0.17 12.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Glutaredoxin PF00462.24 GAX14099.1 - 3.9e-35 119.9 0.0 2.7e-17 62.7 0.0 2.7 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 GAX14099.1 - 1.9e-07 31.0 0.0 4.8e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin SH3BGR PF04908.15 GAX14099.1 - 5.3e-05 23.3 0.0 0.037 14.2 0.0 2.8 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 GAX14099.1 - 0.0057 17.0 0.0 0.82 10.1 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Chor_lyase PF04345.13 GAX14099.1 - 0.057 13.1 0.2 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Chorismate lyase OST3_OST6 PF04756.13 GAX14099.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF5612 PF18462.1 GAX14099.1 - 0.13 12.0 0.0 6 6.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) RdRP PF05183.12 GAX14099.1 - 0.14 10.7 0.0 4.3 5.9 0.0 2.0 1 1 1 2 2 2 0 RNA dependent RNA polymerase Thioredoxin_8 PF13905.6 GAX14099.1 - 0.19 12.0 0.0 3.6 8.0 0.0 2.7 2 1 1 3 3 3 0 Thioredoxin-like Cnd2 PF05786.14 GAX14100.1 - 3.2e-82 277.5 44.0 1.5e-78 265.3 44.0 3.2 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GAX14100.1 - 4.5e-05 23.6 4.6 0.00043 20.5 4.6 2.7 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Pkinase PF00069.25 GAX14103.1 - 1.3e-08 34.5 0.0 9.6e-06 25.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 GAX14103.1 - 1.2e-06 29.0 0.6 0.013 16.1 0.1 4.7 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX14103.1 - 2.1e-06 27.9 1.2 0.0061 16.9 0.1 5.3 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX14103.1 - 1.6e-05 25.3 3.2 0.0011 19.5 0.0 4.6 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 GAX14103.1 - 0.015 14.6 0.3 0.13 11.5 0.3 2.3 1 1 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.6 GAX14103.1 - 0.019 14.3 0.0 0.051 12.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Ank_3 PF13606.6 GAX14103.1 - 0.076 13.6 4.0 1.8 9.4 0.0 4.6 6 0 0 6 6 6 0 Ankyrin repeat ACC_epsilon PF13822.6 GAX14103.1 - 0.18 12.5 1.3 0.89 10.3 1.3 2.2 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Ank PF00023.30 GAX14103.1 - 0.35 11.4 4.6 21 5.8 0.0 4.3 3 1 0 3 3 3 0 Ankyrin repeat VIT1 PF01988.19 GAX14105.1 - 3e-50 171.1 5.8 3.4e-50 170.9 5.8 1.0 1 0 0 1 1 1 1 VIT family Phage_Mu_Gam PF07352.12 GAX14105.1 - 0.015 15.2 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein SseC PF04888.12 GAX14105.1 - 4.4 6.8 8.9 0.39 10.3 0.4 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Iso_dh PF00180.20 GAX14108.1 - 3.2e-135 450.8 0.0 3.7e-135 450.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SR-25 PF10500.9 GAX14109.1 - 0.0094 15.6 25.4 0.0095 15.6 25.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2072 PF09845.9 GAX14109.1 - 0.016 15.5 2.0 0.016 15.4 2.0 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein Dicty_REP PF05086.12 GAX14109.1 - 0.024 12.7 9.3 0.025 12.6 9.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3899 PF13038.6 GAX14109.1 - 0.053 14.0 4.8 0.066 13.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) RNA_pol_Rpc4 PF05132.14 GAX14109.1 - 0.056 13.9 3.8 0.058 13.8 3.8 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 OAD_gamma PF04277.13 GAX14109.1 - 0.057 14.0 2.3 0.068 13.8 2.3 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CDC45 PF02724.14 GAX14109.1 - 0.13 10.5 9.1 0.14 10.4 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein GWT1 PF06423.12 GAX14109.1 - 0.26 11.4 0.9 0.29 11.3 0.9 1.1 1 0 0 1 1 1 0 GWT1 RR_TM4-6 PF06459.12 GAX14109.1 - 0.38 10.5 5.8 0.39 10.5 5.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.8 GAX14109.1 - 0.43 10.3 8.6 0.48 10.2 8.6 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Eapp_C PF10238.9 GAX14109.1 - 0.48 10.5 6.4 0.5 10.4 6.4 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein BCIP PF13862.6 GAX14109.1 - 0.56 10.0 5.3 0.63 9.8 5.3 1.3 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Connexin PF00029.19 GAX14109.1 - 0.57 9.9 6.8 0.58 9.9 6.8 1.0 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 GAX14109.1 - 0.73 8.5 1.3 0.69 8.6 1.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier Ferlin_C PF16165.5 GAX14109.1 - 0.84 9.6 10.2 1.1 9.1 10.2 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Sec62 PF03839.16 GAX14109.1 - 0.86 9.1 10.0 0.87 9.0 10.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 EIIBC-GUT_N PF03612.14 GAX14109.1 - 0.89 9.3 4.4 0.9 9.3 4.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RRT14 PF17075.5 GAX14109.1 - 0.89 9.6 16.6 1 9.5 16.6 1.1 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 Presenilin PF01080.17 GAX14109.1 - 1 8.0 2.7 0.97 8.1 2.7 1.0 1 0 0 1 1 1 0 Presenilin Radial_spoke_3 PF06098.11 GAX14109.1 - 1.3 8.3 9.8 1.3 8.2 9.8 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 CMS1 PF14617.6 GAX14109.1 - 1.7 7.9 17.4 1.9 7.8 17.4 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit XRN_N PF03159.18 GAX14109.1 - 1.7 8.0 8.8 1.8 7.9 8.8 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF2828 PF11443.8 GAX14109.1 - 1.7 6.6 10.3 1.7 6.7 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Cas_Csy4 PF09618.10 GAX14109.1 - 2 8.6 9.7 2.5 8.2 9.7 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) RNA_polI_A34 PF08208.11 GAX14109.1 - 2.6 8.1 21.3 2.8 8.0 21.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop53 PF07767.11 GAX14109.1 - 2.8 7.2 22.7 2.7 7.3 22.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ORC5_C PF14630.6 GAX14109.1 - 2.9 7.3 12.4 3.6 7.0 12.4 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus GAGA_bind PF06217.12 GAX14109.1 - 2.9 8.1 13.2 2.8 8.2 13.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family OATP PF03137.20 GAX14109.1 - 3.7 5.7 7.1 4.3 5.5 7.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Porph_ging PF09697.10 GAX14109.1 - 3.9 8.1 8.0 4.7 7.8 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) MscS_TM PF12794.7 GAX14109.1 - 4.5 6.0 5.3 4.7 6.0 5.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1168 PF06658.12 GAX14109.1 - 4.8 7.0 26.6 6.8 6.5 26.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Spem1 PF15670.5 GAX14109.1 - 5.1 6.6 11.0 5.1 6.6 11.0 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Rot1 PF10681.9 GAX14109.1 - 5.4 6.5 5.3 5.6 6.4 5.3 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal TT_ORF1 PF02956.14 GAX14109.1 - 5.6 5.5 23.0 6.3 5.4 23.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 AP3D1 PF06375.11 GAX14109.1 - 5.8 7.1 25.7 7.2 6.8 25.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 FoP_duplication PF13865.6 GAX14109.1 - 5.9 7.5 19.0 7.8 7.1 19.0 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Peptidase_S49_N PF08496.10 GAX14109.1 - 6.8 6.7 17.7 8.2 6.5 17.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CHD5 PF04420.14 GAX14109.1 - 7.8 6.3 10.0 9.6 6.0 10.0 1.1 1 0 0 1 1 1 0 CHD5-like protein EMC3_TMCO1 PF01956.16 GAX14109.1 - 8.2 6.1 6.2 8 6.2 6.2 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Baculo_PP31 PF05311.11 GAX14109.1 - 8.3 5.8 17.8 9.2 5.7 17.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Jak1_Phl PF17887.1 GAX14109.1 - 8.5 6.3 10.9 10 6.1 10.9 1.1 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Brix PF04427.18 GAX14110.1 - 1.3e-37 129.8 0.1 1.8e-37 129.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain PPP4R2 PF09184.11 GAX14110.1 - 0.014 15.0 17.6 0.019 14.6 17.6 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 GAX14110.1 - 0.037 14.0 16.3 0.056 13.4 16.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 GAX14110.1 - 0.087 13.1 25.7 0.17 12.2 25.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 GAX14110.1 - 0.21 11.3 25.7 0.36 10.5 25.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAX14110.1 - 0.25 10.6 22.2 0.4 9.9 22.2 1.3 1 0 0 1 1 1 0 NOA36 protein UPF0560 PF10577.9 GAX14110.1 - 0.33 9.4 6.5 0.4 9.1 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MMADHC PF10229.9 GAX14110.1 - 0.43 10.3 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type D protein SURF2 PF05477.11 GAX14110.1 - 1 9.0 16.1 1.6 8.3 16.1 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4746 PF15928.5 GAX14110.1 - 1.9 7.8 19.6 3.1 7.1 19.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 GAX14110.1 - 4.8 6.9 21.7 10 5.9 21.7 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MAJIN PF15077.6 GAX14110.1 - 9.4 5.9 8.7 17 5.1 8.7 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein SNF2_N PF00176.23 GAX14112.1 - 8.5e-78 261.5 0.3 2.1e-77 260.2 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAX14112.1 - 2e-27 95.5 0.2 2e-27 95.5 0.2 2.8 3 0 0 3 3 3 1 SLIDE Helicase_C PF00271.31 GAX14112.1 - 1.2e-20 73.9 0.0 9.2e-20 71.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX14112.1 - 3.1e-09 37.1 0.0 3.1e-09 37.1 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 GAX14112.1 - 3.4e-09 37.0 0.4 3.4e-09 37.0 0.4 3.4 4 0 0 4 4 4 1 HMG (high mobility group) box HDA2-3 PF11496.8 GAX14112.1 - 1.2e-07 31.2 0.1 1.2e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 HMG_box_2 PF09011.10 GAX14112.1 - 4.2e-07 30.5 3.0 7.1e-07 29.7 0.5 2.9 2 0 0 2 2 2 1 HMG-box domain Myb_DNA-binding PF00249.31 GAX14112.1 - 4.5e-05 23.6 0.1 0.0018 18.4 0.0 3.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain DEAD PF00270.29 GAX14112.1 - 0.00027 20.8 0.0 0.0018 18.0 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Rsa3 PF14615.6 GAX14114.1 - 7.1e-06 25.5 0.5 2.6e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Ribosome-assembly protein 3 W2 PF02020.18 GAX14115.1 - 4.3e-12 46.0 1.9 1.2e-11 44.6 1.9 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 GAX14115.1 - 1.1e-09 37.7 11.3 2.5e-05 23.8 5.9 3.8 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAX14115.1 - 1.7e-07 31.7 0.3 4.1e-07 30.5 0.3 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 GAX14115.1 - 9.1e-05 22.1 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 GAX14115.1 - 0.00018 19.8 0.3 0.00032 19.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) DUF1330 PF07045.11 GAX14116.1 - 0.15 12.4 2.3 0.2 12.0 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1330) RWD PF05773.22 GAX14117.1 - 0.056 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 RWD domain zf-MYND PF01753.18 GAX14118.1 - 6.5e-08 32.5 16.6 6.5e-08 32.5 16.6 1.8 2 0 0 2 2 2 1 MYND finger Aminotran_3 PF00202.21 GAX14119.1 - 2.4e-73 247.1 0.1 3.1e-73 246.8 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAX14119.1 - 0.025 13.8 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HECT PF00632.25 GAX14122.1 - 9.5e-10 38.4 0.9 2.2e-08 34.0 0.9 2.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF883 PF05957.13 GAX14122.1 - 0.19 12.4 2.7 0.85 10.3 2.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CDC73_C PF05179.14 GAX14123.1 - 2e-40 138.1 0.0 4.7e-40 136.8 0.0 1.6 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal TAXi_N PF14543.6 GAX14124.1 - 3.1e-16 60.1 4.8 6.2e-16 59.1 4.8 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX14124.1 - 5.7e-13 49.0 3.8 2.2e-05 24.0 0.6 3.1 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX14124.1 - 0.057 13.2 0.0 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Myb_DNA-binding PF00249.31 GAX14126.1 - 1e-28 99.3 12.0 1.2e-09 38.2 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX14126.1 - 6.3e-26 90.4 7.3 5.4e-14 52.2 0.5 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GAX14126.1 - 0.4 11.0 1.5 6.8 7.1 0.2 2.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LUC7 PF03194.15 GAX14127.1 - 4e-24 85.7 19.4 1.3e-20 74.2 17.3 2.9 2 1 0 2 2 2 2 LUC7 N_terminus BUD22 PF09073.10 GAX14127.1 - 0.00029 20.3 9.5 0.00038 19.9 9.5 1.2 1 0 0 1 1 1 1 BUD22 ALMT PF11744.8 GAX14127.1 - 0.0081 15.0 7.9 0.011 14.6 7.9 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter V_ATPase_I PF01496.19 GAX14127.1 - 0.32 8.9 10.6 0.4 8.5 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nckap1 PF09735.9 GAX14127.1 - 0.41 8.5 8.6 0.69 7.8 8.4 1.4 1 1 0 1 1 1 0 Membrane-associated apoptosis protein TFB6 PF17110.5 GAX14127.1 - 0.59 9.9 4.7 1.1 8.9 4.7 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Perilipin PF03036.16 GAX14127.1 - 0.79 8.7 16.1 0.15 11.0 12.0 1.6 1 1 1 2 2 2 0 Perilipin family Presenilin PF01080.17 GAX14127.1 - 2.4 6.9 3.7 2.9 6.6 3.7 1.2 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 GAX14127.1 - 3.8 7.2 17.9 6.3 6.5 17.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1118 PF06549.12 GAX14128.1 - 1.4e-13 51.2 21.2 5.6e-07 29.9 3.6 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1118) DUF3493 PF11998.8 GAX14128.1 - 1.2 9.4 5.7 2 8.6 4.4 2.0 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 CDC27 PF09507.10 GAX14129.1 - 0.091 12.1 20.8 0.11 11.9 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.12 GAX14129.1 - 0.95 8.7 27.8 1.7 7.9 27.8 1.5 1 0 0 1 1 1 0 NOA36 protein SID-1_RNA_chan PF13965.6 GAX14129.1 - 1.3 7.3 5.9 15 3.8 5.9 1.9 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 VIR_N PF15912.5 GAX14129.1 - 4.4 6.8 23.6 6 6.4 23.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF5523 PF17661.1 GAX14129.1 - 5.8 6.5 22.9 9 5.9 22.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SDA1 PF05285.12 GAX14129.1 - 7.7 5.8 35.0 11 5.4 35.0 1.2 1 0 0 1 1 1 0 SDA1 PTS_IIA PF02255.16 GAX14130.1 - 4.4 7.4 6.0 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Sulfotransfer_3 PF13469.6 GAX14131.1 - 0.0019 18.6 0.0 0.0019 18.6 0.0 3.7 3 2 0 3 3 3 1 Sulfotransferase family DUF777 PF05606.11 GAX14132.1 - 0.023 14.4 0.1 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF777) P-mevalo_kinase PF04275.14 GAX14132.1 - 0.027 14.4 0.2 5.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Phosphomevalonate kinase HTH_30 PF13556.6 GAX14132.1 - 0.088 12.6 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain GCD14 PF08704.10 GAX14132.1 - 0.11 12.2 3.2 0.88 9.2 0.0 2.7 3 0 0 3 3 3 0 tRNA methyltransferase complex GCD14 subunit PC-Esterase PF13839.6 GAX14133.1 - 5.4e-15 55.9 1.2 7.1e-08 32.5 0.1 4.4 2 1 1 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF3798 PF12683.7 GAX14134.1 - 2.8e-06 27.0 0.5 0.74 9.2 0.0 3.7 4 0 0 4 4 4 3 Protein of unknown function (DUF3798) MutS_I PF01624.20 GAX14134.1 - 0.00041 20.6 0.1 20 5.5 0.0 5.6 6 0 0 6 6 6 1 MutS domain I Lentiviral_Tat PF02998.14 GAX14134.1 - 0.00066 19.7 0.5 10 6.2 0.0 4.4 4 0 0 4 4 4 2 Lentiviral Tat protein Antimicrobial_8 PF08103.11 GAX14134.1 - 0.011 15.8 0.6 56 4.2 0.0 4.6 4 0 0 4 4 4 0 Uperin family DUF5388 PF17363.2 GAX14134.1 - 0.035 14.3 0.0 5.5 7.3 0.0 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5388) DUF3461 PF11944.8 GAX14134.1 - 0.043 14.0 0.0 2 8.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) 3-alpha PF03475.14 GAX14134.1 - 0.049 13.5 0.3 73 3.3 0.0 4.3 4 0 0 4 4 4 0 3-alpha domain BLYB PF05289.11 GAX14134.1 - 0.17 12.1 11.8 10 6.4 0.5 4.5 4 0 0 4 4 4 0 Borrelia hemolysin accessory protein O-FucT PF10250.9 GAX14135.1 - 0.0073 16.1 0.5 0.033 13.9 0.4 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cytochrom_C550 PF14495.6 GAX14135.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain OTU PF02338.19 GAX14136.1 - 4.3e-15 56.3 0.0 8.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAX14136.1 - 0.00022 20.8 0.1 0.32 10.4 0.0 2.3 1 1 0 2 2 2 2 Peptidase C65 Otubain PDZ PF00595.24 GAX14138.1 - 3.6e-07 30.4 0.1 8.9e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX14138.1 - 0.0014 18.9 0.3 0.0039 17.5 0.3 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX14138.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF4690 PF15756.5 GAX14138.1 - 0.49 11.0 2.7 2.6 8.7 0.0 3.0 2 1 1 3 3 3 0 Small Novel Rich in Cartilage DKCLD PF08068.12 GAX14139.1 - 8.9e-32 109.0 2.0 1.5e-29 101.8 0.3 2.9 3 0 0 3 3 3 2 DKCLD (NUC011) domain TruB_N PF01509.18 GAX14139.1 - 1.4e-21 77.4 0.2 3.8e-19 69.5 0.2 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAX14139.1 - 6.6e-20 71.0 1.3 1.3e-19 70.1 1.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 GAX14139.1 - 3.4e-18 65.4 1.3 6.2e-18 64.5 1.3 1.5 1 0 0 1 1 1 1 PUA domain Pkinase PF00069.25 GAX14140.1 - 7.2e-73 245.2 0.0 1.1e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14140.1 - 1.6e-33 116.1 0.0 2.6e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX14140.1 - 7.4e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAX14140.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NifU_N PF01592.16 GAX14140.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 NifU-like N terminal domain NBD94 PF16830.5 GAX14142.1 - 0.14 12.5 0.4 0.29 11.5 0.4 1.4 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH TPR_1 PF00515.28 GAX14143.1 - 0.019 14.8 0.6 7.7 6.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14143.1 - 0.36 11.0 1.6 43 4.6 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat UTP15_C PF09384.10 GAX14145.1 - 7e-21 74.4 0.5 3.3e-20 72.3 0.1 2.2 2 1 1 3 3 3 1 UTP15 C terminal WD40 PF00400.32 GAX14145.1 - 5.8e-06 26.9 10.9 0.00028 21.6 0.1 5.9 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX14145.1 - 6.7e-06 26.3 0.0 5e-05 23.5 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX14145.1 - 0.00056 18.7 0.0 0.14 10.7 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 LsmAD PF06741.13 GAX14145.1 - 0.19 12.3 0.4 0.46 11.1 0.0 1.8 2 0 0 2 2 2 0 LsmAD domain Ion_trans_2 PF07885.16 GAX14146.1 - 2.4e-24 85.1 26.8 3.9e-13 49.2 10.6 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 GAX14146.1 - 0.0012 18.1 13.6 0.025 13.8 3.0 2.3 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 GAX14146.1 - 0.0021 17.9 0.7 0.0093 15.8 0.0 2.2 2 1 0 2 2 2 1 Ligand-gated ion channel IRK PF01007.20 GAX14146.1 - 0.058 13.2 6.2 1.4 8.7 0.3 2.9 2 1 1 3 3 3 0 Inward rectifier potassium channel transmembrane domain CDC45 PF02724.14 GAX14146.1 - 0.15 10.4 9.0 0.22 9.8 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2721 PF11026.8 GAX14146.1 - 0.15 11.9 1.2 16 5.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) His_Phos_1 PF00300.22 GAX14147.1 - 3.3e-10 40.0 0.0 0.00024 20.9 0.0 2.5 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ammonium_transp PF00909.21 GAX14148.1 - 2.3e-111 372.3 31.4 2.8e-111 372.0 31.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 GAX14149.1 - 1.2e-108 363.3 23.9 1.4e-108 363.1 23.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pepdidase_M14_N PF18027.1 GAX14151.1 - 6.4e-22 78.0 1.2 1.3e-21 77.0 1.2 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 GAX14151.1 - 3.6e-18 66.4 0.0 5.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase PPC PF04151.15 GAX14154.1 - 0.00013 23.0 0.6 0.00022 22.3 0.2 1.6 2 0 0 2 2 2 1 Bacterial pre-peptidase C-terminal domain Bestrophin PF01062.21 GAX14155.1 - 1.1e-28 100.5 0.2 1.5e-28 100.0 0.2 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ank_2 PF12796.7 GAX14156.1 - 3.4e-33 114.1 0.1 9e-17 61.4 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX14156.1 - 5.2e-21 74.7 1.2 5e-13 49.3 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX14156.1 - 6.3e-19 67.8 1.6 7.4e-07 29.3 0.0 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX14156.1 - 1.2e-17 62.2 0.0 7.2e-08 32.1 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX14156.1 - 1.2e-14 54.0 0.0 5.8e-07 29.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat DUF5049 PF16468.5 GAX14156.1 - 0.013 15.4 0.5 2 8.4 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5049) CBM_6 PF03422.15 GAX14157.1 - 2e-37 128.3 9.1 1.1e-15 58.1 1.8 3.1 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX14157.1 - 3.4e-20 72.3 2.6 3.6e-06 27.1 0.3 3.4 3 0 0 3 3 3 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX14157.1 - 7.9e-06 26.1 6.9 0.095 13.0 0.9 3.5 3 1 0 3 3 3 3 Carbohydrate binding module (family 35) Ammonium_transp PF00909.21 GAX14158.1 - 1.3e-100 336.9 25.3 1.7e-100 336.5 25.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DDE_Tnp_IS1 PF03400.13 GAX14158.1 - 0.12 12.7 0.2 0.22 11.9 0.2 1.3 1 0 0 1 1 1 0 IS1 transposase Ammonium_transp PF00909.21 GAX14159.1 - 9.3e-100 334.1 27.5 1.1e-99 333.8 27.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TF_Zn_Ribbon PF08271.12 GAX14160.1 - 5.8e-09 35.3 0.3 1.1e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Prim_Zn_Ribbon PF08273.12 GAX14160.1 - 0.00047 20.4 0.2 0.0011 19.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase zf-ribbon_3 PF13248.6 GAX14160.1 - 0.02 14.3 3.9 2.3 7.8 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 GAX14160.1 - 0.058 13.3 0.5 0.15 12.0 0.5 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.6 GAX14160.1 - 0.07 13.5 1.0 0.18 12.2 0.4 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar Elf1 PF05129.13 GAX14160.1 - 0.079 13.0 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like IBR PF01485.21 GAX14160.1 - 0.13 12.5 0.6 0.32 11.3 0.6 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 GAX14160.1 - 0.13 12.0 2.1 3.1 7.6 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DpnI PF06044.12 GAX14160.1 - 0.41 10.3 1.8 0.77 9.4 0.5 2.0 2 0 0 2 2 2 0 Dam-replacing family DUF3797 PF12677.7 GAX14160.1 - 0.43 10.5 4.1 0.23 11.4 1.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) HSCB_C PF07743.13 GAX14161.1 - 4.4e-17 62.3 1.9 4.4e-17 62.3 1.9 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 GAX14161.1 - 4.7e-05 23.4 0.1 8.2e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain TRAPP PF04051.16 GAX14162.1 - 5.1e-26 91.1 0.3 6.7e-26 90.8 0.3 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Exostosin PF03016.15 GAX14163.1 - 2.4e-30 105.8 0.1 5.2e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 Exostosin family RNA_pol_Rpb2_6 PF00562.28 GAX14164.1 - 1.6e-118 396.2 0.0 2.3e-118 395.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAX14164.1 - 1e-53 181.9 0.0 1.5e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 GAX14164.1 - 8.4e-32 109.4 0.1 2e-31 108.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GAX14164.1 - 1.8e-24 86.4 0.0 5.2e-24 84.9 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 GAX14164.1 - 9.5e-24 83.5 0.2 2.5e-23 82.1 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 GAX14164.1 - 1.9e-21 76.0 0.1 8e-21 74.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 GAX14164.1 - 3.6e-14 53.1 0.1 1e-13 51.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Metallophos PF00149.28 GAX14165.1 - 1.5e-17 64.8 0.4 1.5e-17 64.8 0.4 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAX14165.1 - 1.8e-09 38.3 1.8 6.8e-09 36.5 1.8 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAX14165.1 - 0.017 15.6 0.4 0.052 14.1 0.4 1.8 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain zf-TAZ PF02135.16 GAX14166.1 - 4.8e-13 49.4 11.8 4.8e-13 49.4 11.8 2.0 2 0 0 2 2 2 1 TAZ zinc finger zf-BED PF02892.15 GAX14166.1 - 0.021 14.9 0.3 2.8 8.0 0.3 2.4 2 0 0 2 2 2 0 BED zinc finger TauD PF02668.16 GAX14167.1 - 3.8e-24 85.9 0.0 6e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAX14167.1 - 0.0068 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 CsiD DUF2499 PF10693.9 GAX14168.1 - 2.4e-37 127.1 2.4 7.2e-37 125.5 2.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3593 PF12159.8 GAX14168.1 - 1.1e-30 105.5 4.9 2.1e-30 104.6 2.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3593) DUF5379 PF17350.2 GAX14168.1 - 0.018 15.3 0.5 3.5 8.0 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5379) Guanylate_cyc PF00211.20 GAX14169.1 - 4.4e-40 137.2 0.0 1e-39 136.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX14169.1 - 5.2e-31 108.2 0.6 1.1e-30 107.1 0.6 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 GAX14170.1 - 1.3e-48 165.0 0.0 2.3e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX14170.1 - 2.7e-30 105.8 0.6 5.4e-30 104.9 0.6 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 GAX14171.1 - 1e-48 165.4 0.0 2e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX14171.1 - 1.3e-31 110.2 0.7 3.3e-31 108.9 0.7 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Claudin_2 PF13903.6 GAX14171.1 - 0.13 12.0 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction NAD_binding_10 PF13460.6 GAX14172.1 - 4e-40 137.7 0.2 5e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX14172.1 - 2.9e-07 29.8 0.1 4.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GAX14172.1 - 9e-07 28.7 0.6 7.8e-05 22.3 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.25 GAX14172.1 - 4.9e-06 26.1 0.6 9e-06 25.3 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 GAX14172.1 - 2.9e-05 23.7 0.1 5.6e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAX14172.1 - 0.0028 16.9 0.1 0.41 9.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein TrkA_N PF02254.18 GAX14172.1 - 0.0052 17.0 0.3 0.0052 17.0 0.3 1.9 2 1 0 2 2 2 1 TrkA-N domain ADH_zinc_N PF00107.26 GAX14172.1 - 0.13 12.3 0.8 0.22 11.5 0.8 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-DNL PF05180.12 GAX14173.1 - 7.3e-23 80.3 0.1 1.4e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 GAX14173.1 - 0.042 13.6 1.7 0.055 13.2 0.3 1.9 2 0 0 2 2 2 0 CSL zinc finger FANCI_S1-cap PF14674.6 GAX14173.1 - 0.14 12.3 0.2 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 FANCI solenoid 1 cap PPR_2 PF13041.6 GAX14174.1 - 2.2e-06 27.7 0.0 0.46 10.7 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 GAX14174.1 - 0.0014 18.7 0.0 2.7 8.2 0.0 4.3 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX14174.1 - 0.0058 16.0 1.7 0.38 10.1 0.3 3.2 2 1 2 4 4 4 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 GAX14174.1 - 0.066 13.1 0.1 41 4.1 0.1 3.5 2 2 1 3 3 3 0 Mitochondrial ATPase expression HSF_DNA-bind PF00447.17 GAX14175.1 - 3.3e-13 50.0 0.0 5.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HTH_Mga PF08280.11 GAX14175.1 - 0.087 12.9 0.9 6.1 6.9 0.1 2.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Na_Ca_ex PF01699.24 GAX14176.1 - 8.7e-39 132.9 36.8 1.7e-19 70.2 19.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 GAX14177.1 - 2e-39 134.9 36.2 3.9e-20 72.3 18.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ribosomal_S6 PF01250.17 GAX14178.1 - 2.8e-15 56.3 0.0 4.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF719 PF05334.13 GAX14178.1 - 0.51 10.5 2.4 0.76 9.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Ribosomal_S8e PF01201.22 GAX14179.1 - 4.9e-47 159.5 2.7 4.9e-47 159.5 2.7 1.3 2 0 0 2 2 2 1 Ribosomal protein S8e ATP_bind_3 PF01171.20 GAX14181.1 - 4.5e-16 59.1 0.0 1.7e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 GAX14181.1 - 0.00066 19.8 0.0 0.0056 16.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Radical_SAM PF04055.21 GAX14183.1 - 1.8e-14 54.5 0.3 1e-13 52.0 0.3 2.2 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 GAX14183.1 - 0.0003 20.9 0.0 0.00087 19.4 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF4936 PF16290.5 GAX14184.1 - 0.00087 19.9 0.0 0.15 12.8 0.0 2.9 2 2 0 2 2 2 2 Domain of unknown function (DUF4936) Sulfotransfer_1 PF00685.27 GAX14184.1 - 0.052 13.0 0.1 0.56 9.6 0.0 2.2 1 1 0 1 1 1 0 Sulfotransferase domain SET PF00856.28 GAX14185.1 - 1.8e-08 34.9 0.0 3.5e-05 24.2 0.0 3.5 2 1 0 2 2 2 2 SET domain Cupin_4 PF08007.12 GAX14186.1 - 5.2e-55 187.1 0.0 7.2e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein AraC_binding PF02311.19 GAX14186.1 - 0.0035 17.2 0.0 0.022 14.7 0.0 2.3 2 1 2 4 4 4 1 AraC-like ligand binding domain Cupin_1 PF00190.22 GAX14186.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 GAX14186.1 - 0.03 14.0 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Cupin_8 PF13621.6 GAX14186.1 - 0.072 12.8 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Cupin-like domain EamA PF00892.20 GAX14187.1 - 7.8e-26 90.9 21.0 2e-14 54.0 5.5 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAX14187.1 - 0.00075 18.9 5.5 0.0079 15.6 0.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF202 PF02656.15 GAX14187.1 - 0.22 12.0 0.0 0.22 12.0 0.0 4.8 4 3 0 4 4 4 0 Domain of unknown function (DUF202) Abhydrolase_3 PF07859.13 GAX14190.1 - 5.5e-08 32.9 0.2 1e-07 32.1 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX14190.1 - 1.3e-06 29.2 6.4 9.4e-06 26.4 0.4 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX14190.1 - 2.4e-05 23.9 0.0 0.0006 19.4 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF676 PF05057.14 GAX14190.1 - 7.3e-05 22.4 0.0 0.00088 18.8 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAX14190.1 - 0.0043 16.3 0.0 0.014 14.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 GAX14190.1 - 0.015 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 GAX14190.1 - 0.017 14.7 0.1 0.039 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 GAX14190.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Rad1 PF02144.16 GAX14190.1 - 0.033 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 LIDHydrolase PF10230.9 GAX14190.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase BAAT_C PF08840.11 GAX14190.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ank_2 PF12796.7 GAX14191.1 - 1e-07 32.4 0.0 5.9e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX14191.1 - 2.2e-07 31.3 0.1 0.021 15.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX14191.1 - 1.9e-06 28.1 0.7 0.097 13.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAX14191.1 - 2.1e-06 27.6 0.3 0.14 12.8 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX14191.1 - 1.7e-05 25.0 0.2 0.088 13.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) MOZART1 PF12554.8 GAX14191.1 - 0.043 13.6 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated DNA_pol3_gamma3 PF12169.8 GAX14191.1 - 0.061 13.2 0.0 1.7 8.6 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III Sulfotransfer_3 PF13469.6 GAX14192.1 - 1.3e-06 28.9 0.2 0.0015 18.9 0.1 2.5 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_4 PF17784.1 GAX14192.1 - 3.7e-06 26.9 0.0 6.3e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain EXS PF03124.14 GAX14193.1 - 3.7e-74 250.0 21.7 5.1e-74 249.5 21.7 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAX14193.1 - 1.8e-30 107.2 12.7 2.8e-30 106.5 12.7 1.2 1 0 0 1 1 1 1 SPX domain DUF5595 PF18077.1 GAX14193.1 - 0.15 12.2 4.0 0.63 10.2 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) RhoGEF PF00621.20 GAX14193.1 - 0.71 10.1 3.1 1.3 9.3 0.1 2.5 2 1 0 2 2 2 0 RhoGEF domain Phage_Mu_Gam PF07352.12 GAX14193.1 - 1.3 8.9 4.6 5.2 7.0 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Transket_pyr PF02779.24 GAX14194.1 - 1.4e-44 151.9 0.1 2e-44 151.4 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX14194.1 - 3.6e-41 139.9 0.0 9.2e-41 138.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 GAX14194.1 - 0.0086 16.4 0.0 0.072 13.4 0.0 2.3 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Tubulin_3 PF14881.6 GAX14195.1 - 3.6e-05 23.5 0.1 0.00034 20.3 0.1 2.4 1 1 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 GAX14195.1 - 0.00018 21.7 0.0 0.11 12.7 0.0 3.0 3 1 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 GAX14195.1 - 0.0018 18.6 0.3 0.0018 18.6 0.3 3.0 2 1 0 2 2 2 1 Misato Segment II tubulin-like domain DUF2744 PF10910.8 GAX14195.1 - 0.083 12.9 0.4 0.19 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) Mito_carr PF00153.27 GAX14196.1 - 4.2e-50 167.6 2.3 1.8e-18 66.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.22 GAX14197.1 - 2.5e-34 118.9 11.7 1.5e-33 116.4 11.7 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAX14197.1 - 0.00042 20.9 0.3 0.0016 19.1 0.3 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF637 PF04830.13 GAX14197.1 - 0.0067 16.3 0.4 0.015 15.1 0.4 1.6 1 0 0 1 1 1 1 Possible hemagglutinin (DUF637) Toxin_23 PF08093.11 GAX14197.1 - 0.069 13.3 9.2 0.18 12.0 9.2 1.7 1 0 0 1 1 1 0 Magi 5 toxic peptide family INCENP_ARK-bind PF03941.15 GAX14198.1 - 4.8e-16 58.4 0.6 1.1e-15 57.2 0.6 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAP PF02037.27 GAX14198.1 - 0.00013 21.6 0.1 0.00013 21.6 0.1 2.3 3 0 0 3 3 3 1 SAP domain Thiolase_N PF00108.23 GAX14199.1 - 9e-73 244.8 1.1 1.2e-72 244.4 1.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAX14199.1 - 2.7e-46 156.2 0.1 7.9e-46 154.7 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 GAX14199.1 - 0.044 13.6 3.8 0.88 9.5 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Guanylate_cyc PF00211.20 GAX14200.1 - 1e-48 165.4 0.0 2.1e-48 164.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX14200.1 - 1.6e-31 109.9 0.2 3.6e-31 108.7 0.2 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mak16 PF04874.14 GAX14200.1 - 1 10.0 6.4 0.51 11.0 1.6 2.8 2 0 0 2 2 2 0 Mak16 protein C-terminal region Guanylate_cyc PF00211.20 GAX14201.1 - 3.1e-47 160.6 0.0 7e-47 159.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX14201.1 - 2.3e-31 109.4 2.7 2.9e-31 109.0 1.3 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase SH3_17 PF18350.1 GAX14201.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain Guanylate_cyc PF00211.20 GAX14203.1 - 7e-47 159.4 0.0 1.3e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX14203.1 - 1.4e-31 110.1 1.0 3e-31 109.0 1.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Prismane PF03063.20 GAX14204.1 - 2.3e-140 468.7 0.4 2.7e-140 468.5 0.4 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 GAX14205.1 - 3.8e-24 85.5 0.1 3.1e-22 79.3 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX14205.1 - 8.4e-20 71.4 0.1 1.6e-19 70.5 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GAX14205.1 - 9e-11 42.4 0.0 1.5e-08 35.2 0.0 3.0 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Glyco_hydro_18 PF00704.28 GAX14207.1 - 5e-15 56.0 0.0 6.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Proteasome PF00227.26 GAX14208.1 - 1.1e-44 152.3 0.2 1.3e-44 151.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit TPR_11 PF13414.6 GAX14209.1 - 4.9e-05 22.9 6.8 0.066 12.9 3.5 3.6 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 GAX14209.1 - 6.4e-05 22.8 9.6 0.033 14.3 2.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX14209.1 - 0.00019 22.0 5.4 0.006 17.3 0.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX14209.1 - 0.0035 18.0 4.4 0.73 10.5 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat NYD-SP12_N PF15015.6 GAX14209.1 - 0.011 14.2 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_17 PF13431.6 GAX14209.1 - 0.029 14.7 1.0 21 5.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX14209.1 - 0.33 11.7 3.3 20 6.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX14209.1 - 0.5 10.3 8.4 0.55 10.1 1.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CLP_protease PF00574.23 GAX14210.1 - 2.9e-48 164.2 0.0 3.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Clp protease Chloroa_b-bind PF00504.21 GAX14211.1 - 2.1e-39 135.6 0.0 2.6e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein adh_short PF00106.25 GAX14213.1 - 4.8e-27 94.7 0.0 5.8e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX14213.1 - 8.7e-19 68.0 0.1 1.2e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAX14213.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MIF4G_like PF09088.11 GAX14213.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 MIF4G like GTP_EFTU PF00009.27 GAX14215.1 - 4.9e-47 160.0 0.0 7.1e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX14215.1 - 4.2e-09 36.3 0.0 9.4e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GAX14215.1 - 1.1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II LisH PF08513.11 GAX14216.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 LisH Glyco_hydro_18 PF00704.28 GAX14217.1 - 8.2e-17 61.9 0.1 1.4e-16 61.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 GAX14217.1 - 5.3e-10 39.3 1.7 5.3e-10 39.3 1.7 2.4 3 0 0 3 3 3 1 Chitin binding Peritrophin-A domain HECT PF00632.25 GAX14218.1 - 9.2e-82 274.9 0.3 1.7e-81 274.1 0.3 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3945 PF13101.6 GAX14219.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Polyketide_cyc PF03364.20 GAX14219.1 - 0.022 14.9 0.0 0.27 11.5 0.0 2.1 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Peptidase_M43 PF05572.13 GAX14220.1 - 1.3e-13 51.1 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX14220.1 - 1.6e-05 25.2 0.4 3.4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX14220.1 - 0.00022 20.9 0.1 0.00048 19.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX14220.1 - 0.0006 20.3 0.1 0.0018 18.8 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX14220.1 - 0.0032 17.4 0.4 0.0071 16.3 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like GerE PF00196.19 GAX14220.1 - 0.0036 16.8 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Peptidase_M7 PF02031.16 GAX14220.1 - 0.01 15.9 0.4 0.022 14.9 0.4 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DUF4953 PF16313.5 GAX14220.1 - 0.024 13.9 0.1 0.043 13.0 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 GAX14220.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 GAX14220.1 - 0.099 11.6 0.3 0.16 10.9 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 WD40 PF00400.32 GAX14221.1 - 3.2e-40 135.4 21.2 5.5e-06 27.0 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Peptidase_M43 PF05572.13 GAX14221.1 - 1.5e-11 44.4 0.0 4.1e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A ANAPC4_WD40 PF12894.7 GAX14221.1 - 1.8e-07 31.4 0.3 0.1 12.9 0.0 4.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Reprolysin_5 PF13688.6 GAX14221.1 - 1.2e-05 25.5 1.4 3.2e-05 24.2 0.2 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12 BBS2_Mid PF14783.6 GAX14221.1 - 0.00032 20.7 0.2 2.9 8.0 0.0 4.8 3 1 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Reprolysin_4 PF13583.6 GAX14221.1 - 0.00061 19.5 0.1 0.0015 18.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX14221.1 - 0.0016 18.4 0.1 0.0046 16.9 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX14221.1 - 0.0018 18.8 0.0 0.005 17.4 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Nup160 PF11715.8 GAX14221.1 - 0.0051 15.5 5.2 1.8 7.1 0.1 3.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Peptidase_M66 PF10462.9 GAX14221.1 - 0.047 12.6 0.4 0.087 11.8 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 GAX14221.1 - 0.081 12.8 0.1 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 Matrixin DUF4953 PF16313.5 GAX14221.1 - 0.12 11.6 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M7 PF02031.16 GAX14221.1 - 0.15 12.1 1.7 0.21 11.7 0.3 1.9 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family FAE1_CUT1_RppA PF08392.12 GAX14222.1 - 5.1e-106 354.2 0.0 2.9e-105 351.8 0.0 1.9 1 1 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 GAX14222.1 - 1.2e-12 47.9 0.0 1.4e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 GAX14222.1 - 6.7e-12 45.7 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.10 GAX14222.1 - 3.8e-07 29.9 0.0 8.6e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 GAX14222.1 - 0.0051 15.6 0.5 0.25 10.0 0.1 2.3 1 1 0 2 2 2 2 Stage V sporulation protein AD (SpoVAD) DUF1967 PF09269.11 GAX14222.1 - 0.0084 16.0 0.0 0.34 10.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) Chal_sti_synt_N PF00195.19 GAX14222.1 - 0.04 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain ABC1 PF03109.16 GAX14223.1 - 7.2e-24 84.2 0.0 1.8e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 ABC1 family LRR_8 PF13855.6 GAX14224.1 - 4.3e-14 52.0 17.8 7.1e-06 25.7 0.2 4.7 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAX14224.1 - 4.3e-10 39.7 15.7 0.027 14.9 0.6 6.5 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX14224.1 - 0.00073 19.7 13.6 3.2 8.7 0.0 8.9 9 1 1 10 10 10 1 Leucine Rich Repeat LRR_9 PF14580.6 GAX14224.1 - 0.9 9.0 2.5 30 4.1 0.1 3.0 2 1 0 3 3 3 0 Leucine-rich repeat HECT PF00632.25 GAX14225.1 - 4.5e-87 292.4 0.0 7.1e-87 291.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Thioredoxin PF00085.20 GAX14226.1 - 1.1e-24 86.4 0.4 3.7e-24 84.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX14226.1 - 0.00027 21.4 0.0 0.00059 20.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 GAX14226.1 - 0.013 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX14226.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like CdiI_2 PF18593.1 GAX14226.1 - 0.029 15.0 0.0 0.061 14.0 0.0 1.5 1 0 0 1 1 1 0 CdiI immunity protein TraF PF13728.6 GAX14226.1 - 0.036 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 GAX14226.1 - 0.074 12.4 0.0 0.09 12.1 0.0 1.3 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Acetyltransf_1 PF00583.25 GAX14228.1 - 1.7e-08 34.7 0.0 5.6e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX14228.1 - 7.6e-06 26.3 0.0 0.00011 22.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX14228.1 - 0.00095 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX14228.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RPT PF13446.6 GAX14228.1 - 0.097 12.6 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein TUG-UBL1 PF11470.8 GAX14228.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain PAXNEB PF05625.11 GAX14229.1 - 7.7e-34 117.4 0.0 1.7e-32 113.0 0.0 2.6 1 1 0 1 1 1 1 PAXNEB protein Melittin PF01372.17 GAX14229.1 - 0.17 11.9 0.1 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 Melittin CENP-X PF09415.10 GAX14231.1 - 2.1e-07 31.1 0.2 2.7e-07 30.8 0.2 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 GAX14231.1 - 0.031 14.6 0.2 0.076 13.3 0.1 1.8 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UPF0058 PF01893.16 GAX14231.1 - 0.039 14.2 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0058 Aldo_ket_red PF00248.21 GAX14232.1 - 5.7e-27 94.7 0.0 7.4e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HSP70 PF00012.20 GAX14233.1 - 2.7e-251 835.0 3.0 3.1e-251 834.8 3.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX14233.1 - 9.5e-20 70.7 0.3 1.8e-18 66.5 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 GAX14233.1 - 0.00039 19.8 4.2 0.00075 18.9 4.2 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 FtsA PF14450.6 GAX14233.1 - 0.023 15.1 2.7 4.7 7.7 0.0 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 GAX14233.1 - 0.036 13.3 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 GAX14233.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Evr1_Alr PF04777.13 GAX14233.1 - 0.13 12.7 0.2 0.35 11.4 0.1 1.8 2 0 0 2 2 2 0 Erv1 / Alr family TRAF_BIRC3_bd PF16673.5 GAX14233.1 - 2.9 7.8 5.8 1.1 9.1 1.6 2.5 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Aminotran_4 PF01063.19 GAX14234.1 - 7e-13 48.9 0.0 2e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV UCH PF00443.29 GAX14234.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S19e PF01090.19 GAX14235.1 - 1.9e-53 179.8 0.0 2.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e BRX_N PF13713.6 GAX14235.1 - 0.011 15.4 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain TPR_12 PF13424.6 GAX14236.1 - 2e-53 178.6 5.9 3.4e-11 43.3 0.0 6.2 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 GAX14236.1 - 4.4e-27 93.1 5.1 0.0052 16.6 0.1 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14236.1 - 4.5e-21 73.2 20.2 4e-05 23.4 0.2 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX14236.1 - 2.3e-18 64.8 22.2 0.0024 17.9 0.0 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAX14236.1 - 8.7e-16 56.7 5.5 0.23 11.6 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX14236.1 - 5.4e-14 51.3 24.4 0.0012 18.5 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAX14236.1 - 8.3e-13 48.0 9.0 0.023 15.5 0.0 8.0 8 2 2 10 10 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX14236.1 - 8.7e-13 48.3 1.0 1.4e-06 27.9 0.2 3.0 1 1 2 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 GAX14236.1 - 1.4e-11 44.8 4.0 0.75 10.5 0.0 6.8 7 2 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX14236.1 - 1.2e-10 41.7 3.5 0.59 10.7 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat SNAP PF14938.6 GAX14236.1 - 4.1e-10 39.6 15.9 0.0041 16.6 3.1 5.0 3 2 1 5 5 5 3 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 GAX14236.1 - 3.8e-08 33.2 1.3 0.67 10.5 0.0 6.2 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX14236.1 - 0.00045 19.8 9.9 2.6 7.8 0.0 5.3 5 0 0 5 5 5 2 TPR repeat RPN7 PF10602.9 GAX14236.1 - 0.00066 19.4 11.5 0.3 10.8 4.6 4.7 2 2 1 3 3 3 2 26S proteasome subunit RPN7 DUF2225 PF09986.9 GAX14236.1 - 0.00088 19.1 8.6 2.3 7.9 0.1 4.3 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 GAX14236.1 - 0.00094 19.7 17.6 0.91 10.3 0.2 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX14236.1 - 0.0019 17.4 2.3 0.017 14.3 0.3 3.2 2 1 2 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 GAX14236.1 - 0.011 16.2 0.1 32 4.9 0.0 3.8 4 0 0 4 4 3 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 GAX14236.1 - 0.016 15.4 14.3 2.7 8.3 0.1 6.1 3 2 4 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 GAX14236.1 - 0.055 12.9 0.5 6 6.4 0.0 3.6 3 0 0 3 3 3 0 SHNi-TPR ANAPC5 PF12862.7 GAX14236.1 - 0.075 13.1 6.2 4.1 7.5 0.0 4.1 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 DUF3546 PF12066.8 GAX14236.1 - 0.088 13.0 1.9 0.25 11.6 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) PPR PF01535.20 GAX14236.1 - 0.17 12.2 0.6 11 6.5 0.0 4.0 4 0 0 4 4 3 0 PPR repeat Pox_H7 PF04787.12 GAX14236.1 - 0.21 12.1 3.2 2.2 8.8 0.1 3.1 2 1 0 3 3 3 0 Late protein H7 DUF627 PF04781.12 GAX14236.1 - 0.88 9.6 17.5 4 7.5 0.5 5.4 4 2 1 5 5 5 0 Protein of unknown function (DUF627) OAD_gamma PF04277.13 GAX14238.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TRM13 PF05206.14 GAX14239.1 - 2.4e-36 125.6 0.0 3.9e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 GAX14239.1 - 4.7e-11 42.2 4.4 9.3e-11 41.3 4.4 1.5 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 GAX14239.1 - 7.5e-08 32.1 3.1 9.7e-08 31.8 0.4 2.5 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 GAX14239.1 - 7.1e-05 22.8 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX14239.1 - 0.02 14.6 0.3 0.042 13.6 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase GATase_6 PF13522.6 GAX14240.1 - 2.4e-11 44.0 0.0 5e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX14240.1 - 3.1e-10 40.0 0.0 8.5e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 GAX14240.1 - 1.9e-07 30.8 0.0 3.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Rubis-subs-bind PF09273.11 GAX14242.1 - 7.4e-09 36.4 1.0 2.7e-08 34.6 1.4 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 GAX14242.1 - 1.3e-06 28.9 0.0 8.7e-06 26.2 0.0 2.3 2 1 0 2 2 2 1 SET domain Sgf11 PF08209.11 GAX14242.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) SBF_like PF13593.6 GAX14243.1 - 4.2e-72 243.1 19.5 5.5e-72 242.7 19.5 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 GAX14243.1 - 2.1e-06 27.6 8.9 2.1e-06 27.6 8.9 2.1 1 1 0 1 1 1 1 Sodium Bile acid symporter family Radical_SAM PF04055.21 GAX14244.1 - 8e-10 39.3 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 GAX14244.1 - 7e-09 36.1 0.0 2.5e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Methyltransf_16 PF10294.9 GAX14245.1 - 3.4e-18 66.0 1.7 1.8e-17 63.7 0.2 2.6 3 0 0 3 3 3 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAX14245.1 - 2e-06 28.5 0.2 4.7e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX14245.1 - 5.6e-06 27.0 0.3 1.8e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX14245.1 - 7.9e-06 26.4 0.3 3.1e-05 24.6 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX14245.1 - 0.00064 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX14245.1 - 0.00085 19.1 0.2 0.0021 17.9 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX14245.1 - 0.0032 17.1 0.0 0.0072 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 GAX14245.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 GAX14245.1 - 0.027 14.2 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 GAX14245.1 - 0.072 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RRM_1 PF00076.22 GAX14247.1 - 2.3e-67 222.8 0.0 1.5e-17 63.1 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAX14247.1 - 8.3e-13 48.0 0.0 5.6e-06 26.1 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GAX14247.1 - 6.5e-10 39.0 1.7 0.083 13.0 0.0 4.4 4 0 0 4 4 4 3 Limkain b1 RRM_3 PF08777.11 GAX14247.1 - 1.8e-07 31.1 0.3 0.3 11.1 0.0 4.3 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 GAX14247.1 - 7.3e-07 29.1 0.1 4.4e-05 23.4 0.1 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAX14247.1 - 0.00013 22.0 0.0 3.1 8.0 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 GAX14247.1 - 0.00044 19.8 0.0 7.8 6.1 0.0 3.6 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 GAX14247.1 - 0.0037 17.1 0.0 4.2 7.1 0.0 3.5 4 0 0 4 4 4 1 Rrp7 RRM-like N-terminal domain DUF3343 PF11823.8 GAX14247.1 - 0.03 13.8 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) zf-UBR PF02207.20 GAX14248.1 - 3.6e-18 65.5 18.4 9.4e-18 64.2 18.4 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAX14248.1 - 0.0013 18.5 3.3 0.038 13.8 3.3 2.7 1 1 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF1484 PF07363.11 GAX14248.1 - 0.092 13.8 0.3 0.42 11.6 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Gly-zipper_YMGG PF13441.6 GAX14248.1 - 0.67 9.7 7.6 1.9 8.3 7.6 1.8 1 0 0 1 1 1 0 YMGG-like Gly-zipper TLD PF07534.16 GAX14249.1 - 9e-14 51.9 0.0 1.7e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 TLD Peptidase_M14 PF00246.24 GAX14250.1 - 4e-15 56.4 0.0 2.4e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Zinc carboxypeptidase DUF4460 PF14687.6 GAX14250.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) TMEM154 PF15102.6 GAX14250.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF5383 PF17355.2 GAX14250.1 - 0.21 12.0 0.2 0.39 11.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Hydrolase_4 PF12146.8 GAX14251.1 - 4.4e-16 58.9 0.2 3.3e-12 46.2 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GAX14251.1 - 8.2e-10 38.7 0.3 2.1e-06 27.5 0.0 2.7 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAX14251.1 - 1.1e-07 31.8 0.4 7e-06 25.9 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 GAX14251.1 - 2.3e-06 27.4 0.0 3.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 GAX14251.1 - 2.4e-06 28.3 0.0 3.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX14251.1 - 5.4e-06 26.0 0.0 0.0087 15.6 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family PhoPQ_related PF10142.9 GAX14251.1 - 0.00056 18.7 0.0 0.00086 18.1 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein CMS1 PF14617.6 GAX14252.1 - 6.6e-11 42.0 0.0 9.1e-11 41.6 0.0 1.2 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 GAX14252.1 - 0.0017 18.1 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase VPS9 PF02204.18 GAX14253.1 - 3.5e-14 52.9 0.0 1.2e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain PDZ_6 PF17820.1 GAX14253.1 - 1e-08 34.9 0.1 4e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX14253.1 - 7.8e-07 29.4 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX14253.1 - 3.1e-05 24.2 0.0 6.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PX PF00787.24 GAX14253.1 - 0.039 13.9 0.1 0.23 11.5 0.0 2.3 3 0 0 3 3 3 0 PX domain E2F_CC-MB PF16421.5 GAX14254.1 - 3.5e-23 81.8 0.0 5.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 GAX14254.1 - 7e-22 77.3 0.0 1.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TMEM43 PF07787.12 GAX14254.1 - 0.15 11.4 0.2 0.24 10.8 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 Agenet PF05641.12 GAX14255.1 - 6e-06 26.6 0.5 2.1e-05 24.9 0.2 2.1 2 0 0 2 2 2 1 Agenet domain PCI PF01399.27 GAX14256.1 - 3.7e-22 78.8 0.8 2e-20 73.2 0.9 2.7 2 0 0 2 2 2 1 PCI domain RPN6_N PF18055.1 GAX14256.1 - 6.7e-22 78.1 0.2 6.7e-22 78.1 0.2 2.9 4 0 0 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_MalT PF17874.1 GAX14256.1 - 0.00072 19.0 5.1 0.049 13.0 3.3 2.7 2 1 1 3 3 3 2 MalT-like TPR region DDRGK PF09756.9 GAX14256.1 - 0.0013 18.4 0.9 0.0028 17.3 0.9 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_12 PF13424.6 GAX14256.1 - 0.0065 16.7 7.5 0.028 14.7 1.4 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DnaGprimase_HBD PF16730.5 GAX14256.1 - 0.012 15.7 0.4 0.052 13.6 0.4 2.1 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain TPR_19 PF14559.6 GAX14256.1 - 0.037 14.5 7.2 5.2 7.6 0.5 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14256.1 - 0.068 13.3 5.3 41 4.6 0.1 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat NIBRIN_BRCT_II PF16508.5 GAX14256.1 - 0.084 13.2 0.2 0.95 9.8 0.1 2.5 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein RPN6_C_helix PF18503.1 GAX14256.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain SAP PF02037.27 GAX14257.1 - 1.2e-10 40.9 2.8 2e-10 40.2 2.8 1.4 1 0 0 1 1 1 1 SAP domain CS PF04969.16 GAX14257.1 - 5.1e-08 33.8 0.2 2.2e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 CS domain Telomere_Sde2_2 PF13297.6 GAX14257.1 - 0.00034 20.2 0.1 0.00087 18.9 0.1 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal DIMCO_N PF16844.5 GAX14257.1 - 0.23 11.8 1.5 16 5.9 0.4 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Tir_receptor_M PF03549.14 GAX14257.1 - 1 9.8 4.4 26 5.3 0.1 2.9 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) intimin-binding domain MRG PF05712.13 GAX14258.1 - 2.1e-28 99.0 0.1 6.5e-28 97.4 0.1 1.8 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 GAX14258.1 - 2.3e-05 24.2 0.2 5.9e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 GAX14258.1 - 0.037 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain DUF3886 PF13025.6 GAX14258.1 - 0.17 12.1 6.4 0.45 10.7 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Cation_efflux PF01545.21 GAX14259.1 - 1.6e-25 90.0 5.8 2.2e-25 89.6 5.8 1.1 1 0 0 1 1 1 1 Cation efflux family tRNA-synt_His PF13393.6 GAX14260.1 - 9.2e-44 150.0 0.0 1.3e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 GAX14260.1 - 1.2e-15 57.5 0.1 2.4e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAX14260.1 - 7e-08 32.6 0.0 1.4e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 GAX14260.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF2999 PF11212.8 GAX14260.1 - 0.12 12.6 0.2 0.46 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) PGI PF00342.19 GAX14261.1 - 4.4e-240 797.3 0.1 5e-240 797.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase PGI PF00342.19 GAX14262.1 - 2.2e-139 465.2 0.0 5.7e-126 421.0 0.0 2.0 2 0 0 2 2 2 2 Phosphoglucose isomerase Neuro_bHLH PF12533.8 GAX14262.1 - 0.062 14.5 0.1 0.18 13.0 0.0 1.9 2 0 0 2 2 2 0 Neuronal helix-loop-helix transcription factor Ras PF00071.22 GAX14263.1 - 1.8e-57 193.5 0.0 2.3e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX14263.1 - 1e-36 125.8 0.1 1.4e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX14263.1 - 2.9e-15 56.2 0.0 3.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAX14263.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX14263.1 - 2.1e-05 24.1 0.0 6e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAX14263.1 - 0.00046 19.7 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX14263.1 - 0.0012 18.9 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX14263.1 - 0.0021 18.0 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 GAX14263.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 GAX14263.1 - 0.19 11.1 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Methyltransf_10 PF05971.12 GAX14265.1 - 5.8e-31 107.9 0.0 1.8e-30 106.3 0.0 1.8 1 1 0 1 1 1 1 RNA methyltransferase Haemagg_act PF05860.13 GAX14265.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 haemagglutination activity domain Thioredoxin_8 PF13905.6 GAX14266.1 - 6.9e-24 84.0 0.0 1.1e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 GAX14266.1 - 6.2e-09 35.8 0.0 4.8e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAX14266.1 - 1.5e-06 28.6 0.0 4e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAX14266.1 - 0.00079 19.3 0.0 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GAX14266.1 - 0.00098 18.9 0.0 0.0052 16.5 0.0 2.1 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 GAX14266.1 - 0.039 13.7 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin NADH_4Fe-4S PF10589.9 GAX14266.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Thioredoxin_7 PF13899.6 GAX14266.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Bromodomain PF00439.25 GAX14268.1 - 2.3e-15 56.4 0.0 4.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 GAX14268.1 - 0.0001 22.1 9.9 0.0001 22.1 9.9 3.2 2 1 1 3 3 3 1 PHD-finger SNF5 PF04855.12 GAX14268.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 zf-4CXXC_R1 PF10497.9 GAX14268.1 - 1.5 9.1 21.5 4.4 7.6 2.6 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 CorA PF01544.18 GAX14269.1 - 0.37 10.1 1.6 0.99 8.7 1.6 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ribosomal_L4 PF00573.22 GAX14270.1 - 1.2e-36 126.2 0.1 2.1e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAX14270.1 - 9.3e-19 67.3 2.6 2.1e-18 66.1 1.7 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Metallophos PF00149.28 GAX14271.1 - 6.1e-08 33.4 0.1 1e-07 32.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nup88 PF10168.9 GAX14272.1 - 0.00033 18.6 7.1 0.00049 18.0 7.1 1.1 1 0 0 1 1 1 1 Nuclear pore component Ribosomal_L13 PF00572.18 GAX14273.1 - 5.3e-06 26.7 0.2 0.0001 22.5 0.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L13 Trp_leader2 PF08056.11 GAX14273.1 - 0.16 11.9 0.3 0.45 10.5 0.3 1.7 1 0 0 1 1 1 0 Tryptophan operon leader peptide P5CR_dimer PF14748.6 GAX14274.1 - 3.3e-43 146.1 2.0 5.9e-43 145.3 1.2 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAX14274.1 - 2.3e-13 50.5 2.8 2.5e-13 50.4 1.2 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAX14274.1 - 0.00013 22.2 0.6 0.00025 21.2 0.6 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HisG PF01634.18 GAX14275.1 - 1e-53 181.6 0.2 1.4e-53 181.1 0.2 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 GAX14275.1 - 9.1e-22 77.0 0.1 2.3e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 GAX14275.1 - 0.0038 17.2 0.2 0.0099 15.8 0.2 1.7 1 1 0 1 1 1 1 NMT1/THI5 like Ribosomal_L25p PF01386.19 GAX14276.1 - 3.7e-11 43.4 0.0 1.2e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 GAX14276.1 - 1.6e-06 28.4 0.0 3.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Methyltransf_16 PF10294.9 GAX14277.1 - 1.4e-13 50.9 0.0 2.1e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase zf-primase PF09329.11 GAX14279.1 - 2.8e-06 27.0 6.0 9.7e-06 25.3 6.0 1.9 1 1 0 1 1 1 1 Primase zinc finger GCV_H PF01597.19 GAX14280.1 - 4.8e-43 145.9 0.1 5.7e-43 145.7 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 GAX14280.1 - 1.8e-05 24.7 0.1 3.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 GAX14280.1 - 0.00018 21.3 0.3 0.00037 20.3 0.2 1.6 1 1 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 GAX14280.1 - 0.019 14.7 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 AOC_like PF18678.1 GAX14280.1 - 0.029 14.0 0.0 7.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Allene oxide cyclase barrel like domain CMAS PF02353.20 GAX14280.1 - 0.13 11.5 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GP70 PF17429.2 GAX14280.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Gene product 70 Methyltrans_RNA PF04452.14 GAX14281.1 - 1.1e-28 100.1 0.0 1.9e-27 96.0 0.0 2.0 1 1 0 1 1 1 1 RNA methyltransferase WW PF00397.26 GAX14282.1 - 1.7e-07 31.2 3.4 4.8e-07 29.7 3.4 1.8 1 0 0 1 1 1 1 WW domain VWA_2 PF13519.6 GAX14282.1 - 0.021 15.5 0.5 0.13 12.9 0.1 2.5 3 0 0 3 3 3 0 von Willebrand factor type A domain GCD14 PF08704.10 GAX14283.1 - 9.3e-60 202.3 0.4 2e-59 201.2 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 GAX14283.1 - 2.6e-08 33.8 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAX14283.1 - 1.6e-05 25.9 0.0 3.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX14283.1 - 0.00017 22.3 0.0 0.00058 20.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAX14283.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 GAX14283.1 - 0.0026 18.5 0.0 0.011 16.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GAX14283.1 - 0.0035 16.8 0.0 0.0084 15.5 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAX14283.1 - 0.012 16.2 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.6 GAX14283.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term RrnaAD PF00398.20 GAX14283.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 GAX14283.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ArsA_ATPase PF02374.15 GAX14284.1 - 8.8e-116 386.3 0.0 4.8e-58 196.8 0.0 2.5 2 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 GAX14284.1 - 6.2e-22 78.0 0.0 1.2e-11 44.8 0.0 3.3 2 2 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX14284.1 - 3.4e-20 72.7 3.9 2.5e-10 40.5 0.1 4.4 3 2 0 3 3 3 2 AAA domain ParA PF10609.9 GAX14284.1 - 3e-13 49.8 9.6 8.5e-07 28.7 0.8 4.4 5 0 0 5 5 5 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 GAX14284.1 - 1.3e-08 34.6 1.5 0.00018 21.1 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 GAX14284.1 - 7.8e-08 32.1 1.9 0.022 14.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain MeaB PF03308.16 GAX14284.1 - 3.4e-07 29.5 2.7 0.00019 20.5 0.0 3.0 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAX14284.1 - 5e-07 30.3 0.8 0.0039 17.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 GAX14284.1 - 7.1e-07 28.7 2.1 0.0009 18.6 0.1 2.6 2 1 0 2 2 2 2 Zeta toxin PhoH PF02562.16 GAX14284.1 - 1e-06 28.4 0.1 0.084 12.3 0.0 3.3 3 0 0 3 3 3 2 PhoH-like protein SRP54 PF00448.22 GAX14284.1 - 3.3e-06 26.9 6.7 0.00078 19.1 0.2 3.9 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 GAX14284.1 - 3.7e-06 26.6 0.5 0.074 12.5 0.0 2.5 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ AAA_18 PF13238.6 GAX14284.1 - 6.5e-05 23.5 0.8 0.059 13.9 0.0 3.8 4 0 0 4 4 3 1 AAA domain VirC1 PF07015.11 GAX14284.1 - 0.00013 21.3 0.7 0.0033 16.7 0.2 2.6 2 0 0 2 2 2 1 VirC1 protein NB-ARC PF00931.22 GAX14284.1 - 0.0005 19.3 0.3 0.41 9.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 GAX14284.1 - 0.00063 19.5 0.2 0.39 10.4 0.0 2.7 2 2 0 2 2 2 1 AAA domain MipZ PF09140.11 GAX14284.1 - 0.00064 19.1 5.6 0.0012 18.2 0.4 3.0 3 0 0 3 3 3 1 ATPase MipZ IstB_IS21 PF01695.17 GAX14284.1 - 0.0007 19.4 0.0 0.88 9.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_30 PF13604.6 GAX14284.1 - 0.00092 19.0 1.7 0.31 10.7 0.2 3.1 3 0 0 3 3 3 1 AAA domain DnaB_C PF03796.15 GAX14284.1 - 0.0018 17.7 0.4 2.5 7.4 0.0 2.8 3 0 0 3 3 3 2 DnaB-like helicase C terminal domain DUF1611 PF07755.11 GAX14284.1 - 0.0026 17.1 0.9 0.0081 15.5 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1611_C) P-loop domain RNA_helicase PF00910.22 GAX14284.1 - 0.0032 17.8 0.2 3.4 8.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase CLP1_P PF16575.5 GAX14284.1 - 0.0058 16.5 0.4 0.84 9.4 0.0 3.5 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 GAX14284.1 - 0.0071 15.9 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 GAX14284.1 - 0.011 15.1 0.2 2.2 7.5 0.0 3.2 3 0 0 3 3 3 0 KaiC RsgA_GTPase PF03193.16 GAX14284.1 - 0.015 15.2 1.1 8.9 6.2 0.4 3.1 3 0 0 3 3 3 0 RsgA GTPase PIF1 PF05970.14 GAX14284.1 - 0.024 13.8 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 0 PIF1-like helicase FtsK_SpoIIIE PF01580.18 GAX14284.1 - 0.032 13.6 0.8 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 GAX14284.1 - 0.036 14.0 1.8 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain LpxK PF02606.14 GAX14284.1 - 0.047 12.8 2.3 1.6 7.8 0.1 2.9 3 0 0 3 3 3 0 Tetraacyldisaccharide-1-P 4'-kinase Mur_ligase_M PF08245.12 GAX14284.1 - 0.054 13.5 0.0 10 6.1 0.1 2.5 2 0 0 2 2 2 0 Mur ligase middle domain AAA_33 PF13671.6 GAX14284.1 - 0.1 12.7 0.1 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAX14284.1 - 0.12 11.6 0.3 0.94 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_26 PF13500.6 GAX14284.1 - 0.15 11.9 2.7 14 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAX14284.1 - 0.15 11.8 3.8 0.38 10.5 0.3 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Peptidase_M15 PF01427.17 GAX14284.1 - 0.18 11.5 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase APS_kinase PF01583.20 GAX14284.1 - 0.27 11.1 0.8 29 4.5 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 GAX14284.1 - 0.3 11.3 2.0 4.1 7.6 0.8 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAX14284.1 - 0.53 10.7 2.9 38 4.7 0.0 3.6 5 0 0 5 5 2 0 ATPase family associated with various cellular activities (AAA) CTP_synth_N PF06418.14 GAX14284.1 - 3.7 6.8 6.3 0.24 10.7 0.3 2.1 3 0 0 3 3 1 0 CTP synthase N-terminus MCM PF00493.23 GAX14285.1 - 3.4e-95 317.4 0.0 6.1e-95 316.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX14285.1 - 3.3e-33 114.2 0.3 9.5e-33 112.7 0.3 1.8 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX14285.1 - 4.2e-28 97.6 0.3 1.4e-27 96.0 0.3 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 GAX14285.1 - 1e-07 32.5 1.1 3.2e-06 27.7 1.1 2.6 1 1 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 GAX14285.1 - 0.0003 20.7 0.0 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAX14285.1 - 0.00038 19.9 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX14285.1 - 0.0082 16.1 0.0 0.025 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SpoU_methylase PF00588.19 GAX14286.1 - 6.3e-27 94.5 0.1 4.1e-20 72.4 0.0 2.8 2 1 1 3 3 3 2 SpoU rRNA Methylase family SfsA PF03749.13 GAX14287.1 - 8.5e-23 80.8 0.1 3.7e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Sugar fermentation stimulation protein RE domain TPR_MLP1_2 PF07926.12 GAX14290.1 - 0.0077 16.3 14.3 0.0077 16.3 14.3 4.6 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 GAX14290.1 - 0.51 10.6 8.9 0.94 9.8 2.6 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CALCOCO1 PF07888.11 GAX14290.1 - 3.6 6.3 50.7 0.45 9.3 20.3 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 GAX14290.1 - 5.7 6.2 27.1 1.3 8.3 8.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) ApoO PF09769.9 GAX14291.1 - 0.014 15.4 0.7 1.2 9.1 0.0 3.5 3 1 1 4 4 4 0 Apolipoprotein O PTRF_SDPR PF15237.6 GAX14291.1 - 0.059 13.0 16.1 0.21 11.2 2.0 2.8 1 1 0 2 2 2 0 PTRF/SDPR family DUF5082 PF16888.5 GAX14291.1 - 0.18 12.1 20.7 0.24 11.7 0.7 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) YabA PF06156.13 GAX14291.1 - 0.23 12.1 22.6 0.37 11.5 9.0 3.3 2 2 1 3 3 3 0 Initiation control protein YabA NPV_P10 PF05531.12 GAX14291.1 - 2.1 8.9 5.5 6.5 7.3 3.2 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Flu_M1_C PF08289.11 GAX14291.1 - 2.7 8.3 6.3 11 6.3 0.9 3.0 3 0 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain DASH_Duo1 PF08651.10 GAX14291.1 - 7.8 6.4 8.0 0.8 9.5 0.6 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF948 PF06103.11 GAX14291.1 - 8.3 6.8 9.5 8.4 6.7 0.9 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 GAX14291.1 - 8.6 5.9 13.4 0.63 9.6 5.4 2.6 1 1 1 2 2 2 0 fzo-like conserved region Exo84_C PF16528.5 GAX14292.1 - 1.3e-08 35.0 1.0 8.4e-05 22.5 0.2 3.4 2 1 1 3 3 3 2 Exocyst component 84 C-terminal Vps51 PF08700.11 GAX14292.1 - 0.00014 21.8 0.5 0.0027 17.8 0.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 GAX14292.1 - 0.0016 18.5 3.0 0.0085 16.2 0.1 2.7 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 PH PF00169.29 GAX14292.1 - 0.0022 18.4 0.0 0.0049 17.4 0.0 1.6 1 0 0 1 1 1 1 PH domain SGTA_dimer PF16546.5 GAX14292.1 - 0.04 13.7 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Homodimerisation domain of SGTA DUF1681 PF07933.14 GAX14293.1 - 2.1e-28 98.9 0.0 2.6e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Sulfotransfer_2 PF03567.14 GAX14295.1 - 0.05 13.5 2.9 0.12 12.3 1.5 2.0 1 1 1 2 2 2 0 Sulfotransferase family Nodulin-like PF06813.13 GAX14296.1 - 5e-14 52.4 8.1 1.3e-13 51.0 8.1 1.7 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 GAX14296.1 - 1.7e-08 33.8 34.6 3.6e-08 32.7 1.0 3.0 2 1 0 3 3 3 2 Major Facilitator Superfamily Rib_recp_KP_reg PF05104.12 GAX14297.1 - 0.088 13.9 1.1 0.16 13.0 1.1 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Cation_efflux PF01545.21 GAX14298.1 - 9.3e-08 32.0 10.8 1.3e-07 31.6 10.8 1.2 1 0 0 1 1 1 1 Cation efflux family UbiA PF01040.18 GAX14298.1 - 0.003 16.9 9.9 0.0084 15.4 3.3 2.9 2 1 1 3 3 3 2 UbiA prenyltransferase family Tmemb_14 PF03647.13 GAX14298.1 - 0.0057 17.4 2.4 1.6 9.5 0.7 3.0 2 1 0 2 2 2 1 Transmembrane proteins 14C DUF872 PF05915.12 GAX14298.1 - 0.0082 16.3 5.9 2.1 8.5 0.3 3.0 1 1 1 3 3 3 2 Eukaryotic protein of unknown function (DUF872) MFS_1 PF07690.16 GAX14298.1 - 0.02 13.8 7.6 0.049 12.5 7.7 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily TssN PF17555.2 GAX14298.1 - 0.051 12.9 2.4 0.087 12.2 2.4 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN NCE101 PF11654.8 GAX14298.1 - 0.06 13.0 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 DUF2370 PF10176.9 GAX14298.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DPM3 PF08285.11 GAX14298.1 - 0.21 11.8 0.2 0.21 11.8 0.2 2.5 2 1 1 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4203 PF13886.6 GAX14298.1 - 0.23 11.1 10.2 0.092 12.4 6.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4203) TauE PF01925.19 GAX14298.1 - 0.24 11.0 11.8 0.051 13.2 5.4 2.2 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE TctB PF07331.11 GAX14298.1 - 0.33 11.2 9.7 0.74 10.1 9.8 1.7 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF202 PF02656.15 GAX14298.1 - 0.61 10.6 15.2 7.2 7.1 1.2 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MARVEL PF01284.23 GAX14298.1 - 1.6 8.8 19.6 0.45 10.5 1.2 3.2 3 0 0 3 3 3 0 Membrane-associating domain DUF4212 PF13937.6 GAX14298.1 - 2.6 8.5 8.4 1.8 9.0 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) DUF1761 PF08570.10 GAX14298.1 - 2.8 8.2 10.2 0.78 10.0 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1761) Polysacc_synt_C PF14667.6 GAX14298.1 - 9.9 6.2 13.4 0.69 10.0 5.1 2.6 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain PCI PF01399.27 GAX14299.1 - 2.5e-14 53.7 0.0 6e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 GAX14299.1 - 1e-07 31.5 4.0 1.7e-07 30.8 1.8 2.3 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix DNA_pol_A_exo1 PF01612.20 GAX14300.1 - 1.2e-14 54.4 0.0 1.9e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease MBOAT_2 PF13813.6 GAX14300.1 - 4.4e-11 42.9 0.6 9.8e-11 41.8 0.6 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SAM_LFY PF01698.16 GAX14300.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Floricaula / Leafy protein SAM domain Pirin PF02678.16 GAX14304.1 - 3.4e-19 68.8 0.1 6.1e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 GAX14304.1 - 1.5e-14 53.9 0.1 3.9e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 GAX14304.1 - 0.00051 19.7 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Pirin_C PF05726.13 GAX14304.1 - 0.011 16.1 0.1 0.046 14.1 0.0 1.9 2 0 0 2 2 2 0 Pirin C-terminal cupin domain Acetyltransf_1 PF00583.25 GAX14305.1 - 3.1e-10 40.3 0.0 4.6e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAX14305.1 - 2.1e-06 27.6 0.0 4.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAX14305.1 - 5e-06 26.5 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX14305.1 - 3.4e-05 24.2 0.0 0.00016 22.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX14305.1 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 GAX14305.1 - 0.11 12.4 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase HlyE PF06109.13 GAX14306.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Haemolysin E (HlyE) TsaE PF02367.17 GAX14307.1 - 2.6e-25 88.8 0.0 3.2e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAX14307.1 - 0.04 14.1 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAX14307.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC HEPN_SAV2148 PF18725.1 GAX14308.1 - 0.028 13.8 1.6 0.09 12.2 1.6 1.9 1 0 0 1 1 1 0 SAV2148-like HEPN Ras PF00071.22 GAX14309.1 - 7.6e-21 74.4 0.0 8.5e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 GAX14309.1 - 0.0035 16.9 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B adh_short_C2 PF13561.6 GAX14309.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Terminase_2 PF03592.16 GAX14310.1 - 0.1 13.1 1.0 1.4 9.4 0.4 2.1 2 0 0 2 2 2 0 Terminase small subunit GAT PF03127.14 GAX14310.1 - 0.65 10.3 3.5 1.2 9.4 0.2 3.0 3 1 0 3 3 3 0 GAT domain DUF760 PF05542.11 GAX14311.1 - 2.3e-27 95.1 0.0 3.7e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF760) EF-hand_7 PF13499.6 GAX14311.1 - 1.7e-10 41.2 4.8 5.4e-10 39.6 4.8 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX14311.1 - 1.2e-09 37.1 10.3 0.00013 21.3 1.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX14311.1 - 1.5e-09 37.0 7.6 0.00013 21.6 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX14311.1 - 4.3e-08 32.3 9.5 0.00066 19.1 2.7 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAX14311.1 - 3e-06 27.0 5.0 0.00077 19.3 1.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair NMT PF01233.19 GAX14312.1 - 1.5e-73 245.9 0.0 1e-72 243.2 0.0 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 GAX14312.1 - 3.7e-73 245.5 0.0 5.3e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 GAX14312.1 - 0.0015 18.6 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX14312.1 - 0.0032 17.7 0.0 0.0063 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-MYND PF01753.18 GAX14313.1 - 0.00014 21.8 10.4 0.00042 20.4 10.4 1.8 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 GAX14313.1 - 0.025 15.8 2.6 0.054 14.7 2.6 1.6 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF2318 PF10080.9 GAX14313.1 - 0.056 13.6 1.5 0.13 12.4 1.5 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_1 PF00130.22 GAX14313.1 - 0.45 10.4 5.5 1.1 9.2 5.5 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 GAX14313.1 - 1.3 9.2 6.8 4 7.7 1.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Peptidase_C14 PF00656.22 GAX14314.1 - 3.1e-22 79.7 0.2 6.7e-22 78.6 0.2 1.6 2 0 0 2 2 2 1 Caspase domain RPN7 PF10602.9 GAX14317.1 - 1.3e-41 142.2 0.7 2.1e-41 141.5 0.7 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAX14317.1 - 6.6e-14 52.3 0.0 1.5e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain Barstar PF01337.18 GAX14317.1 - 0.0023 17.9 0.0 0.19 11.8 0.0 2.8 2 1 0 2 2 2 1 Barstar (barnase inhibitor) DUF3209 PF11483.8 GAX14317.1 - 0.054 14.0 3.0 0.22 12.0 3.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3209) HTH_10 PF04967.12 GAX14317.1 - 0.065 13.0 0.1 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain Pyr_redox_2 PF07992.14 GAX14318.1 - 2.5e-12 46.7 0.1 3.1e-10 39.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX14318.1 - 2.1e-05 25.0 0.0 0.41 11.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX14318.1 - 0.0014 18.6 0.0 0.004 17.2 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAX14318.1 - 0.002 18.3 1.1 0.004 17.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX14318.1 - 0.0021 17.3 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.21 GAX14318.1 - 0.0078 15.5 0.1 0.033 13.5 0.3 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 GAX14318.1 - 0.017 14.0 0.1 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.21 GAX14318.1 - 0.14 11.5 0.0 18 4.6 0.0 2.3 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 GAX14318.1 - 0.15 12.1 0.0 5.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DNA_gyraseB PF00204.25 GAX14319.1 - 4.3e-47 159.8 0.0 8.4e-47 158.9 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 GAX14319.1 - 3.3e-29 100.8 0.1 8e-29 99.6 0.1 1.7 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.22 GAX14319.1 - 5e-20 71.6 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.26 GAX14319.1 - 4.6e-17 62.5 0.1 2.3e-16 60.3 0.1 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX14319.1 - 0.005 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HpcH_HpaI PF03328.14 GAX14320.1 - 4e-28 98.0 0.0 4.8e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Cnd3 PF12719.7 GAX14321.1 - 1.7e-30 106.2 5.1 4.7e-30 104.8 0.0 3.6 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GAX14321.1 - 5.6e-08 33.1 8.8 0.029 14.7 0.0 5.9 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.22 GAX14321.1 - 6.3e-07 29.1 4.0 4.4 7.8 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 GAX14321.1 - 0.027 15.0 2.9 6.7 7.3 0.0 4.3 6 0 0 6 6 6 0 HEAT-like repeat BUD22 PF09073.10 GAX14321.1 - 0.25 10.6 3.4 0.43 9.9 3.4 1.3 1 0 0 1 1 1 0 BUD22 DUF4611 PF15387.6 GAX14321.1 - 0.68 10.2 5.8 0.35 11.1 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) WD40 PF00400.32 GAX14322.1 - 1.5e-24 85.7 0.3 6.6e-05 23.6 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX14322.1 - 4.1e-12 46.2 0.0 0.00081 19.6 0.0 4.3 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 GAX14322.1 - 0.016 14.8 0.0 0.048 13.2 0.0 1.7 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region SNRNP27 PF08648.12 GAX14325.1 - 0.052 13.6 0.6 0.12 12.5 0.6 1.5 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins TPR_1 PF00515.28 GAX14326.1 - 1.7e-16 59.2 6.6 9.9e-07 28.3 0.0 6.5 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14326.1 - 9.7e-16 56.6 9.6 0.0049 16.9 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX14326.1 - 1.4e-11 44.2 2.3 5.6 8.1 0.0 7.7 5 3 3 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX14326.1 - 1.6e-09 37.8 6.9 0.072 13.3 0.0 5.5 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAX14326.1 - 1.5e-08 35.2 0.4 1.1 10.0 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX14326.1 - 4.3e-08 33.5 1.7 0.12 12.9 0.0 6.0 5 1 2 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX14326.1 - 1.3e-07 31.8 7.5 2.3 8.6 0.1 6.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX14326.1 - 3e-07 30.0 1.7 0.0087 15.7 0.0 5.5 7 0 0 7 7 6 1 TPR repeat TPR_MalT PF17874.1 GAX14326.1 - 5.5e-07 29.3 3.2 0.00064 19.2 2.9 3.4 2 2 1 3 3 3 1 MalT-like TPR region TPR_8 PF13181.6 GAX14326.1 - 1.1e-05 25.2 12.0 3.8 8.0 0.0 7.4 10 0 0 10 10 5 2 Tetratricopeptide repeat zf-RING_2 PF13639.6 GAX14326.1 - 1.2e-05 25.5 12.1 3e-05 24.3 12.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX14326.1 - 0.0012 18.8 5.1 0.0012 18.8 5.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX14326.1 - 0.0016 18.3 11.4 0.0035 17.2 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_10 PF13374.6 GAX14326.1 - 0.0021 17.9 6.6 14 5.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 GAX14326.1 - 0.003 17.4 8.9 0.0059 16.4 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX14326.1 - 0.003 17.3 11.0 0.0066 16.3 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX14326.1 - 0.0052 16.6 10.0 0.012 15.4 10.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 MIT PF04212.18 GAX14326.1 - 0.0054 16.8 0.3 0.11 12.5 0.0 3.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain zf-RING_5 PF14634.6 GAX14326.1 - 0.0064 16.4 9.9 0.014 15.3 9.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_17 PF13431.6 GAX14326.1 - 0.007 16.7 0.0 16 6.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX14326.1 - 0.0091 15.7 4.7 4.1 7.1 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GAX14326.1 - 0.0092 16.1 0.3 0.37 11.0 0.2 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF1771 PF08590.10 GAX14326.1 - 0.014 15.8 3.8 0.95 9.9 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) DUF3856 PF12968.7 GAX14326.1 - 0.049 13.7 3.0 28 4.8 0.0 4.2 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) zf-C3HC4_4 PF15227.6 GAX14326.1 - 0.055 13.6 8.9 0.14 12.4 8.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAX14326.1 - 0.059 13.7 8.9 0.15 12.3 8.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain YfdX PF10938.8 GAX14326.1 - 0.16 11.9 5.6 12 5.8 0.1 4.1 3 1 0 3 3 3 0 YfdX protein TPR_6 PF13174.6 GAX14326.1 - 0.6 10.9 4.5 1.8e+02 3.1 0.1 5.5 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF4363 PF14276.6 GAX14326.1 - 0.64 10.2 5.0 4 7.6 0.0 4.1 3 1 0 4 4 4 0 Domain of unknown function (DUF4363) FUSC-like PF12805.7 GAX14326.1 - 0.85 8.6 3.7 1.4 7.9 0.5 2.8 1 1 2 4 4 4 0 FUSC-like inner membrane protein yccS zf-ANAPC11 PF12861.7 GAX14326.1 - 1 9.4 4.4 2.2 8.4 4.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PUF PF00806.19 GAX14327.1 - 0.00053 19.5 0.1 0.24 11.2 0.0 4.0 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat HAT_KAT11 PF08214.11 GAX14328.1 - 8.5e-28 97.6 0.0 8.5e-28 97.6 0.0 2.9 3 0 0 3 3 3 1 Histone acetylation protein zf-TAZ PF02135.16 GAX14328.1 - 3.4e-19 69.1 43.0 1.1e-11 45.0 19.6 5.0 6 0 0 6 6 6 2 TAZ zinc finger Bromodomain PF00439.25 GAX14328.1 - 3.4e-17 62.3 0.0 1.1e-16 60.6 0.0 2.0 1 0 0 1 1 1 1 Bromodomain KIX_2 PF16987.5 GAX14328.1 - 3e-05 23.9 0.0 0.0002 21.3 0.0 2.5 1 0 0 1 1 1 1 KIX domain PHD PF00628.29 GAX14328.1 - 3.1e-05 23.8 5.6 3.1e-05 23.8 5.6 4.1 4 0 0 4 4 4 1 PHD-finger ZZ PF00569.17 GAX14328.1 - 0.00021 21.1 7.4 0.00021 21.1 7.4 3.1 5 0 0 5 5 5 1 Zinc finger, ZZ type DUF902 PF06001.13 GAX14328.1 - 0.033 14.7 3.2 0.049 14.1 1.6 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) DSPc PF00782.20 GAX14329.1 - 9.2e-09 35.2 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX14329.1 - 0.00014 21.5 0.0 0.00019 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAX14329.1 - 0.0011 19.1 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Pkinase PF00069.25 GAX14330.1 - 1.6e-73 247.3 0.0 1.9e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14330.1 - 6.3e-46 156.8 0.0 7.7e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX14330.1 - 0.0034 16.2 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAX14330.1 - 0.0098 15.2 0.0 0.064 12.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like EGF_2 PF07974.13 GAX14331.1 - 1.1e-13 51.3 74.1 0.0011 19.3 2.9 8.5 7 3 0 7 7 7 5 EGF-like domain EGF PF00008.27 GAX14331.1 - 1.3e-11 44.5 85.8 0.005 17.1 5.3 9.5 8 1 0 8 8 8 7 EGF-like domain hEGF PF12661.7 GAX14331.1 - 6.9 7.5 69.6 1.3 9.8 6.8 10.9 8 3 0 8 8 8 0 Human growth factor-like EGF Vps5 PF09325.10 GAX14332.1 - 1.6e-32 112.9 4.2 2.2e-32 112.5 4.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 GAX14332.1 - 5.8e-20 71.4 0.0 1.2e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR PF03114.18 GAX14332.1 - 1.9e-11 44.1 4.0 2.6e-11 43.7 4.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.9 GAX14332.1 - 1.3e-05 24.8 3.1 0.0029 17.1 3.1 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein adh_short PF00106.25 GAX14333.1 - 6.4e-23 81.2 0.0 1e-19 70.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX14333.1 - 7e-08 32.3 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX14333.1 - 0.00053 19.9 0.5 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 GAX14333.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Synaptobrevin PF00957.21 GAX14334.1 - 2.1e-16 59.5 0.2 3.6e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAX14334.1 - 2.6e-11 43.4 0.0 5.9e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2721 PF11026.8 GAX14334.1 - 0.026 14.4 0.4 0.044 13.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) FAM163 PF15069.6 GAX14334.1 - 0.03 14.8 0.2 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 FAM163 family CdiI_4 PF18624.1 GAX14334.1 - 0.32 11.5 4.9 0.15 12.5 1.1 2.3 2 1 1 3 3 3 0 CDI immunity protein PBP1_TM PF14812.6 GAX14334.1 - 1.5 9.2 4.2 35 4.9 1.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2997 PF11211.8 GAX14335.1 - 1.4e-19 69.6 0.0 2.2e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2997) DnaJ_C PF01556.18 GAX14336.1 - 1.8e-36 125.5 0.9 2.6e-36 124.9 0.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX14336.1 - 4.6e-27 93.9 2.2 8.8e-27 93.0 2.2 1.5 1 0 0 1 1 1 1 DnaJ domain RuBisCO_small PF00101.20 GAX14337.1 - 0.004 17.1 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Ribulose bisphosphate carboxylase, small chain TPR_17 PF13431.6 GAX14337.1 - 0.0059 16.9 4.1 0.15 12.5 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14337.1 - 0.0075 16.3 1.5 0.017 15.2 0.7 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX14337.1 - 0.009 16.5 1.4 0.022 15.3 1.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX14337.1 - 0.051 13.8 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GAX14337.1 - 1.6 8.7 4.5 0.4 10.6 0.6 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DegT_DnrJ_EryC1 PF01041.17 GAX14338.1 - 6.8e-50 170.4 0.0 8.6e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 GAX14338.1 - 2.7e-13 49.9 0.2 6.4e-13 48.6 0.2 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX14338.1 - 6.1e-05 21.7 0.0 0.00025 19.7 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAX14338.1 - 0.0033 16.4 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.19 GAX14338.1 - 0.0096 14.5 0.1 0.014 14.0 0.1 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF4806 PF16064.5 GAX14338.1 - 0.064 13.6 0.3 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) EGF PF00008.27 GAX14339.1 - 0.007 16.6 52.6 0.12 12.6 0.8 5.7 4 2 0 4 4 4 4 EGF-like domain EGF_2 PF07974.13 GAX14339.1 - 0.35 11.3 52.0 0.21 12.0 13.5 5.3 4 2 0 4 4 4 0 EGF-like domain EGF_2 PF07974.13 GAX14340.1 - 0.0027 18.0 114.2 0.0099 16.2 1.9 10.4 9 2 0 9 9 9 5 EGF-like domain Rax2 PF12768.7 GAX14340.1 - 0.0029 17.1 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity GalKase_gal_bdg PF10509.9 GAX14340.1 - 0.026 14.1 0.2 1.9 8.1 0.1 3.2 4 0 0 4 4 4 0 Galactokinase galactose-binding signature EGF PF00008.27 GAX14340.1 - 0.035 14.4 112.1 1 9.7 6.7 11.9 11 0 0 11 11 11 0 EGF-like domain Adaptin_N PF01602.20 GAX14341.1 - 3.6e-95 319.5 0.5 5.3e-95 318.9 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 GAX14341.1 - 1.7e-17 63.6 0.0 6.1e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 GAX14341.1 - 2.7e-09 37.3 1.1 2.4e-07 30.9 0.1 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Alpha_adaptinC2 PF02883.20 GAX14341.1 - 5e-08 33.2 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.22 GAX14341.1 - 0.12 12.7 2.3 20 5.8 0.1 3.7 2 0 0 2 2 2 0 HEAT repeat NUC153 PF08159.12 GAX14342.1 - 1.3e-10 40.8 4.0 2.8e-10 39.8 4.0 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 GAX14342.1 - 6.5e-06 26.8 1.3 0.21 12.5 0.2 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat SAM_adeno_trans PF01887.16 GAX14342.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase ANAPC4_WD40 PF12894.7 GAX14342.1 - 0.16 12.3 0.0 3.1 8.2 0.0 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain 2-Hacid_dh_C PF02826.19 GAX14343.1 - 2.5e-29 101.9 0.0 4.3e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX14343.1 - 1.4e-14 53.9 0.0 2.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 GAX14343.1 - 0.00036 20.2 0.1 0.00085 19.0 0.1 1.6 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 GAX14343.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_4 PF13291.6 GAX14343.1 - 0.024 15.2 0.2 0.052 14.1 0.2 1.5 1 0 0 1 1 1 0 ACT domain 2-Hacid_dh_C PF02826.19 GAX14344.1 - 8.5e-29 100.2 0.1 1.8e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX14344.1 - 2e-18 66.3 0.1 3.4e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAX14344.1 - 3.3e-07 30.6 0.0 1.1e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 GAX14344.1 - 2.8e-05 23.8 0.2 5.1e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 GAX14344.1 - 0.00054 19.3 0.2 0.0016 17.8 0.2 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ACT_4 PF13291.6 GAX14344.1 - 0.0091 16.6 0.4 0.02 15.5 0.4 1.6 1 0 0 1 1 1 1 ACT domain F420_oxidored PF03807.17 GAX14344.1 - 0.02 15.4 0.1 0.061 13.9 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 GAX14344.1 - 0.03 14.4 0.2 0.084 12.9 0.2 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 GAX14344.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 GAX14344.1 - 0.084 12.6 1.3 0.2 11.4 0.1 2.1 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase COG5 PF10392.9 GAX14346.1 - 0.075 13.2 0.4 0.075 13.2 0.4 2.9 2 1 0 2 2 2 0 Golgi transport complex subunit 5 RVT_2 PF07727.14 GAX14347.1 - 7e-21 75.0 0.0 1.4e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX14347.1 - 5.1e-05 23.4 0.1 0.00037 20.7 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain DNA_pol_A PF00476.20 GAX14348.1 - 2.4e-70 237.5 0.0 4.7e-69 233.3 0.0 2.8 1 1 0 2 2 2 1 DNA polymerase family A SAP PF02037.27 GAX14348.1 - 4.3e-14 51.9 14.5 1.1e-13 50.6 0.9 3.8 3 1 0 3 3 3 2 SAP domain DNA_pol_A_exo1 PF01612.20 GAX14348.1 - 6.4e-09 35.7 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease LETM1 PF07766.13 GAX14348.1 - 8.6e-05 22.0 1.3 0.00011 21.7 0.4 1.6 2 0 0 2 2 2 1 LETM1-like protein 40S_S4_C PF16121.5 GAX14348.1 - 0.094 12.4 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus Telomere_Sde2_2 PF13297.6 GAX14348.1 - 1.8 8.3 7.9 0.16 11.6 1.1 2.9 2 1 1 3 3 3 0 Telomere stability C-terminal DUF1800 PF08811.11 GAX14349.1 - 5.2e-41 141.1 0.0 1.6e-24 86.7 0.5 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX14349.1 - 5.2e-33 114.7 0.0 9.1e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX14349.1 - 0.0042 17.2 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PT PF04886.12 GAX14349.1 - 2.6 7.7 6.6 5.6 6.6 6.6 1.5 1 0 0 1 1 1 0 PT repeat SnoaL_3 PF13474.6 GAX14350.1 - 1.2e-34 119.2 1.0 8e-11 42.3 0.1 3.3 3 0 0 3 3 3 3 SnoaL-like domain CaMKII_AD PF08332.10 GAX14350.1 - 2.4e-32 111.8 0.1 2e-12 47.3 0.0 3.2 3 0 0 3 3 3 3 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 GAX14350.1 - 3.1e-28 98.3 5.8 1.6e-08 34.9 0.1 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 GAX14350.1 - 1.1e-16 61.4 2.8 1.3e-05 25.7 0.1 3.3 3 0 0 3 3 3 3 SnoaL-like domain SnoaL_4 PF13577.6 GAX14350.1 - 1.5e-09 38.0 7.9 0.045 13.9 0.5 5.0 3 2 0 3 3 3 3 SnoaL-like domain Alfin PF12165.8 GAX14350.1 - 0.017 14.8 0.0 14 5.4 0.0 3.2 3 0 0 3 3 3 0 Alfin MecA_N PF05223.11 GAX14350.1 - 0.12 12.7 0.0 40 4.5 0.0 3.1 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain Anth_synt_I_N PF04715.13 GAX14350.1 - 0.14 12.4 0.1 28 4.9 0.0 2.9 3 0 0 3 3 3 0 Anthranilate synthase component I, N terminal region TetR_C_28 PF17937.1 GAX14350.1 - 0.35 11.4 2.5 2.6 8.6 0.0 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain GH-E PF14410.6 GAX14350.1 - 0.93 9.9 4.0 5.9 7.4 0.1 2.9 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Methyltransf_31 PF13847.6 GAX14352.1 - 1.9e-07 31.0 0.0 2.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX14352.1 - 1.1e-05 26.0 0.0 1.6e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX14352.1 - 0.00029 20.7 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX14352.1 - 0.0013 19.4 0.0 0.002 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX14352.1 - 0.0013 19.4 0.1 0.0024 18.6 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAX14352.1 - 0.018 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 GAX14352.1 - 0.019 15.0 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 GAX14352.1 - 0.019 14.6 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.12 GAX14352.1 - 0.02 14.5 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_33 PF10017.9 GAX14352.1 - 0.045 12.9 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_18 PF12847.7 GAX14352.1 - 0.047 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FKBP_C PF00254.28 GAX14353.1 - 7.7e-18 64.6 0.0 2.5e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PDZ_6 PF17820.1 GAX14353.1 - 0.00016 21.5 0.3 0.00069 19.4 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX14353.1 - 0.0003 21.1 0.4 0.0014 18.9 0.1 2.1 2 0 0 2 2 2 1 PDZ domain DUF3394 PF11874.8 GAX14353.1 - 0.009 15.7 0.2 0.089 12.5 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3394) DUF1681 PF07933.14 GAX14353.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1681) adh_short PF00106.25 GAX14354.1 - 1.4e-06 28.0 0.0 5.1e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAX14354.1 - 0.0013 18.7 0.2 0.0031 17.5 0.2 1.6 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 GAX14355.1 - 1.5e-30 106.5 0.0 2.7e-30 105.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14355.1 - 7.6e-22 77.8 0.0 1.6e-21 76.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2439 PF10382.9 GAX14356.1 - 1e-06 28.9 0.0 3.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) MatE PF01554.18 GAX14357.1 - 4e-08 33.1 16.5 4.5e-05 23.2 0.8 3.1 3 1 0 3 3 3 2 MatE Saf_2TM PF18303.1 GAX14357.1 - 0.0062 16.1 6.2 3.5 7.2 0.0 3.5 3 0 0 3 3 3 3 SAVED-fused 2TM effector domain Glyco_tranf_2_4 PF13704.6 GAX14358.1 - 1.5e-05 25.4 2.3 1.5e-05 25.4 2.3 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX14358.1 - 0.021 14.5 0.8 0.053 13.2 0.8 1.8 1 1 0 1 1 1 0 Glycosyltransferase family 92 NUDIX PF00293.28 GAX14359.1 - 2.3e-17 63.3 0.1 4.3e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain CinA PF02464.17 GAX14359.1 - 5.9e-17 61.7 0.8 9.7e-16 57.7 0.8 2.2 1 1 0 1 1 1 1 Competence-damaged protein zf-NADH-PPase PF09297.11 GAX14359.1 - 1.7e-05 24.3 3.8 3.8e-05 23.2 3.8 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 GAX14359.1 - 0.00023 21.7 0.0 0.00058 20.5 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Tub PF01167.18 GAX14360.1 - 2.9e-47 161.4 0.0 6.3e-46 157.1 0.0 2.5 2 1 0 2 2 2 1 Tub family RdRP PF05183.12 GAX14361.1 - 1.2e-28 100.1 0.0 2.7e-15 56.1 0.0 2.1 1 1 0 2 2 2 2 RNA dependent RNA polymerase KOW PF00467.29 GAX14361.1 - 3e-07 30.2 7.4 0.0036 17.2 0.9 2.5 2 0 0 2 2 2 2 KOW motif Methyltrans_RNA PF04452.14 GAX14362.1 - 3.4e-34 118.2 0.0 3e-33 115.1 0.0 2.0 1 1 0 1 1 1 1 RNA methyltransferase dUTPase PF00692.19 GAX14363.1 - 4.6e-45 152.4 0.0 5.6e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase PC-Esterase PF13839.6 GAX14364.1 - 0.0014 18.5 0.1 0.002 17.9 0.1 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Ank_2 PF12796.7 GAX14365.1 - 4e-15 56.2 0.2 7.3e-08 32.9 0.4 4.3 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX14365.1 - 9.4e-15 53.3 0.2 0.0011 19.2 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAX14365.1 - 6.4e-11 42.3 3.9 7e-06 26.2 0.1 5.4 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX14365.1 - 1.2e-10 41.4 1.5 0.00083 19.7 0.1 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 GAX14365.1 - 4.3e-09 36.7 2.5 3.4e-05 24.3 0.1 4.5 4 1 2 6 6 6 3 Ankyrin repeats (many copies) zf-CCHC PF00098.23 GAX14366.1 - 4.9e-24 83.3 20.9 3.5e-08 33.2 3.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 GAX14366.1 - 2.3e-06 27.5 13.8 0.015 15.3 0.9 3.2 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 GAX14366.1 - 9.6e-05 22.0 14.7 0.36 10.6 1.5 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 GAX14366.1 - 0.014 15.1 12.6 0.75 9.6 0.4 3.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Viral_NABP PF05515.11 GAX14366.1 - 0.033 14.1 5.2 0.056 13.3 5.2 1.5 1 1 0 1 1 1 0 Viral nucleic acid binding zf-CCHC_6 PF15288.6 GAX14366.1 - 0.2 11.5 13.0 1.7 8.6 0.9 3.2 3 0 0 3 3 3 0 Zinc knuckle IBR PF01485.21 GAX14366.1 - 0.26 11.5 12.0 1.5 9.1 6.1 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-CCHC_2 PF13696.6 GAX14366.1 - 0.37 10.7 17.5 1.4 8.8 1.0 3.5 3 1 0 3 3 3 0 Zinc knuckle Zn_ribbon_recom PF13408.6 GAX14366.1 - 1.1 9.8 14.9 1.3 9.6 1.7 2.5 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain DZR PF12773.7 GAX14366.1 - 1.3 9.1 14.3 78 3.4 14.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon FoP_duplication PF13865.6 GAX14366.1 - 2.8 8.6 19.8 0.24 11.9 15.2 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 zinc_ribbon_2 PF13240.6 GAX14366.1 - 5.3 6.9 10.6 8.9 6.2 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain A_deamin PF02137.18 GAX14367.1 - 1.4e-34 120.1 0.3 1.8e-33 116.4 0.2 2.2 2 0 0 2 2 2 2 Adenosine-deaminase (editase) domain DHR-2 PF06920.13 GAX14368.1 - 0.026 13.2 1.5 0.37 9.4 0.2 2.4 2 0 0 2 2 2 0 Dock homology region 2 Phage_pRha PF09669.10 GAX14368.1 - 0.044 14.3 0.0 19 5.9 0.0 2.7 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) TMEM65 PF10507.9 GAX14369.1 - 5.3e-44 148.6 6.5 1.2e-43 147.4 6.5 1.7 1 0 0 1 1 1 1 Transmembrane protein 65 GAF_2 PF13185.6 GAX14369.1 - 2.1e-13 50.7 0.0 9.5e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 GAX14369.1 - 1.9e-12 48.0 0.0 3.9e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 GAX14369.1 - 0.00041 20.7 0.2 0.7 10.2 0.0 2.8 3 0 0 3 3 3 2 GAF domain DUF702 PF05142.12 GAX14369.1 - 0.34 11.4 1.3 0.43 11.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF1043 PF06295.12 GAX14369.1 - 0.76 9.8 3.4 0.8 9.7 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1043) DUF4730 PF15873.5 GAX14369.1 - 6.2 7.2 7.7 0.66 10.3 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) Bromodomain PF00439.25 GAX14370.1 - 3.1e-18 65.6 0.0 6.8e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain MA3 PF02847.17 GAX14370.1 - 0.13 12.2 0.1 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 MA3 domain DUF309 PF03745.14 GAX14371.1 - 0.028 14.1 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF309) DXP_redisom_C PF08436.12 GAX14371.1 - 0.08 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Hist_deacetyl PF00850.19 GAX14372.1 - 2.7e-37 128.9 0.1 3.7e-37 128.5 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PC-Esterase PF13839.6 GAX14373.1 - 0.031 14.0 0.1 0.12 12.1 0.0 1.9 2 1 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Pkinase PF00069.25 GAX14374.1 - 1.2e-15 57.6 0.0 1.7e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14374.1 - 3.7e-12 46.1 0.0 5.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Potex_coat PF06184.11 GAX14374.1 - 0.039 13.5 0.2 0.44 10.1 0.1 2.2 2 0 0 2 2 2 0 Potexvirus coat protein V-ATPase_G PF03179.15 GAX14375.1 - 6.9e-26 90.8 4.1 8.3e-26 90.6 4.1 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 GAX14375.1 - 0.0014 18.1 5.6 0.021 14.3 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) PALP PF00291.25 GAX14376.1 - 3.9e-44 151.2 0.2 3.4e-42 144.9 0.2 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FdhD-NarQ PF02634.15 GAX14376.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 FdhD/NarQ family Glyco_transf_41 PF13844.6 GAX14377.1 - 5.2e-29 101.0 0.5 8.2e-29 100.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_2 PF07719.17 GAX14377.1 - 0.00084 19.3 0.1 3 8.2 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX14377.1 - 0.003 17.3 0.0 2.2 8.2 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX14377.1 - 0.039 14.2 0.3 78 3.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF758 PF05527.11 GAX14377.1 - 0.41 10.6 0.1 0.41 10.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF758) SNF2_N PF00176.23 GAX14378.1 - 3.4e-57 193.7 0.0 5.6e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX14378.1 - 5.7e-18 65.3 0.0 1.9e-17 63.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX14378.1 - 1.5e-11 44.6 0.0 5.9e-11 42.7 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAX14378.1 - 8.9e-09 34.9 0.2 2.1e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAX14378.1 - 0.00039 20.2 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Glyco_trans_1_2 PF13524.6 GAX14378.1 - 0.0068 16.8 0.0 1.1 9.7 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 SWI2_SNF2 PF18766.1 GAX14378.1 - 0.053 13.2 0.0 0.17 11.5 0.0 1.9 1 1 0 1 1 1 0 SWI2/SNF2 ATPase CLTH PF10607.9 GAX14379.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Inhibitor_G39P PF11417.8 GAX14379.1 - 0.14 12.7 0.4 0.37 11.3 0.4 1.7 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P TspO_MBR PF03073.15 GAX14380.1 - 9.8e-33 113.1 13.9 1.3e-32 112.7 13.9 1.1 1 0 0 1 1 1 1 TspO/MBR family HSP20 PF00011.21 GAX14381.1 - 0.18 12.0 0.2 0.62 10.2 0.0 1.9 2 0 0 2 2 2 0 Hsp20/alpha crystallin family HA PF03457.14 GAX14382.1 - 1.2e-37 128.0 6.0 5.1e-20 71.6 0.3 2.3 2 0 0 2 2 2 2 Helicase associated domain Arnt_C PF18583.1 GAX14382.1 - 0.033 13.8 0.1 0.07 12.8 0.1 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain MSC PF09402.10 GAX14384.1 - 0.13 11.7 0.1 0.18 11.3 0.1 1.4 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain Cupin_8 PF13621.6 GAX14385.1 - 6.2e-08 32.7 0.9 2.6e-07 30.6 0.9 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX14385.1 - 1.5e-07 31.2 0.4 2.7e-07 30.4 0.4 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 GAX14385.1 - 0.00052 20.4 2.0 0.0023 18.3 0.4 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 GAX14385.1 - 0.0051 16.4 0.0 0.0085 15.7 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 GAX14385.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.8 1 0 0 1 1 1 0 Cupin domain HTH_ABP1_N PF18107.1 GAX14385.1 - 0.13 12.0 1.0 0.51 10.1 0.1 2.2 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain HSF_DNA-bind PF00447.17 GAX14386.1 - 4.2e-29 101.0 1.5 6.8e-29 100.3 1.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DENN PF02141.21 GAX14387.1 - 4.7e-46 157.1 4.1 7.5e-46 156.4 4.1 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAX14387.1 - 4.7e-15 56.1 0.2 1.3e-14 54.7 0.2 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 GAX14387.1 - 1.2e-10 41.2 2.6 3.1e-10 39.9 2.6 1.8 1 0 0 1 1 1 1 dDENN domain PPR PF01535.20 GAX14387.1 - 2.1e-06 27.6 0.6 0.00044 20.3 0.0 2.9 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 GAX14387.1 - 1.7e-05 24.8 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAX14387.1 - 2.7e-05 24.3 0.0 0.0016 18.6 0.0 2.7 1 1 1 2 2 2 2 PPR repeat family PPR_1 PF12854.7 GAX14387.1 - 0.0027 17.3 0.6 0.0093 15.7 0.0 2.2 2 0 0 2 2 2 1 PPR repeat TSP_NTD PF17804.1 GAX14387.1 - 0.059 13.6 2.6 0.11 12.7 0.3 2.5 2 0 0 2 2 2 0 Tail specific protease N-terminal domain RhlB PF12300.8 GAX14387.1 - 0.067 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Methyltransf_25 PF13649.6 GAX14388.1 - 7.5e-07 29.8 0.0 1.4e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX14388.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAX14388.1 - 1.5e-05 24.7 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 GAX14388.1 - 7.7e-05 23.4 0.0 0.00015 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX14388.1 - 0.0004 21.0 0.0 0.00069 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX14388.1 - 0.003 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Endonuclease_5 PF04493.14 GAX14388.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Endonuclease V Methyltransf_18 PF12847.7 GAX14388.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAX14388.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SCIMP PF15050.6 GAX14389.1 - 0.15 12.6 0.0 1.8 9.0 0.0 2.0 2 0 0 2 2 2 0 SCIMP protein LPMO_10 PF03067.15 GAX14390.1 - 7e-25 88.8 0.4 1.4e-24 87.8 0.1 1.6 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading XRN_M PF17846.1 GAX14391.1 - 3.8e-93 312.8 1.5 1.4e-62 212.1 1.4 2.3 2 0 0 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 GAX14391.1 - 3.1e-91 305.1 0.0 5.3e-91 304.4 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 GAX14391.1 - 4.8e-25 88.4 0.0 9e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 GAX14391.1 - 1.4e-17 63.5 0.5 3.9e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 GAX14391.1 - 0.0018 18.4 0.0 0.0069 16.6 0.0 2.0 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain Topoisom_bac PF01131.20 GAX14392.1 - 1.1e-102 344.1 2.5 1.2e-102 344.0 0.0 2.1 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 GAX14392.1 - 4.3e-15 55.8 0.0 9.7e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Toprim domain SAPS PF04499.15 GAX14392.1 - 0.91 8.2 5.8 1.9 7.2 5.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 GAX14392.1 - 7.8 4.5 7.5 11 4.0 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Response_reg PF00072.24 GAX14393.1 - 9.1e-30 103.1 0.1 3.2e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 GAX14393.1 - 8.5e-14 50.9 0.0 3.8e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 GAX14393.1 - 0.0068 16.1 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 GAX14393.1 - 0.015 14.8 0.1 0.044 13.3 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Mo25 PF08569.11 GAX14393.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Mo25-like HTH_24 PF13412.6 GAX14393.1 - 0.047 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 GAX14393.1 - 0.068 13.0 0.3 6.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain N-glycanase_N PF09112.10 GAX14393.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal 60KD_IMP PF02096.20 GAX14394.1 - 4e-32 111.4 3.9 4e-32 111.4 3.9 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein SNF2_N PF00176.23 GAX14395.1 - 2.1e-48 164.9 0.0 6e-48 163.3 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX14395.1 - 2.9e-17 63.0 0.0 1.8e-16 60.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX14395.1 - 6.9e-08 32.7 0.1 3.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX14395.1 - 0.028 14.7 0.7 1.6 9.0 0.0 3.6 3 1 0 3 3 3 0 AAA domain UIM PF02809.20 GAX14395.1 - 0.036 14.0 2.3 0.23 11.4 2.3 2.6 1 0 0 1 1 1 0 Ubiquitin interaction motif HA PF03457.14 GAX14396.1 - 4.2e-37 126.3 2.8 8e-20 71.0 0.1 2.2 2 0 0 2 2 2 2 Helicase associated domain PCI PF01399.27 GAX14397.1 - 6.6e-12 45.9 0.6 3.4e-11 43.6 0.0 2.5 3 0 0 3 3 3 1 PCI domain RPN5_C PF18098.1 GAX14397.1 - 3e-09 36.8 0.1 1.1e-08 35.0 0.1 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain GRAS PF03514.14 GAX14397.1 - 0.15 10.9 3.5 0.099 11.6 1.5 1.6 2 0 0 2 2 2 0 GRAS domain family PPR_2 PF13041.6 GAX14398.1 - 1.4e-33 114.8 10.2 9.8e-07 28.9 0.0 12.3 12 2 1 13 13 13 6 PPR repeat family PPR_3 PF13812.6 GAX14398.1 - 1.1e-26 92.6 0.0 1.4e-08 34.7 0.0 9.5 7 3 3 10 10 10 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX14398.1 - 5e-24 83.7 7.6 0.016 14.9 0.1 13.1 12 2 0 12 12 12 7 PPR repeat PPR_long PF17177.4 GAX14398.1 - 2.2e-11 43.6 6.7 0.0024 17.2 0.8 5.2 2 1 5 7 7 7 4 Pentacotripeptide-repeat region of PRORP PrkA PF06798.12 GAX14398.1 - 6.9e-05 22.6 1.8 0.023 14.3 0.2 2.9 2 1 0 2 2 2 2 PrkA serine protein kinase C-terminal domain PPR PF01535.20 GAX14398.1 - 0.0035 17.5 38.1 0.14 12.5 0.6 14.6 16 2 0 16 16 16 1 PPR repeat RecC_C PF17946.1 GAX14398.1 - 0.035 13.9 0.7 3.7 7.3 0.0 3.5 4 0 0 4 4 4 0 RecC C-terminal domain DUF4003 PF13170.6 GAX14398.1 - 0.05 13.0 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) GRIP PF01465.20 GAX14399.1 - 3.5e-11 42.8 0.6 9.9e-11 41.4 0.0 2.2 2 0 0 2 2 2 1 GRIP domain DUF1664 PF07889.12 GAX14399.1 - 0.0014 18.6 6.2 0.0014 18.6 6.2 15.7 2 2 14 18 18 18 4 Protein of unknown function (DUF1664) Spo0A_C PF08769.11 GAX14399.1 - 0.026 14.6 1.1 0.12 12.5 1.1 2.2 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Myb_DNA-bind_7 PF15963.5 GAX14400.1 - 6e-22 77.3 3.1 6e-22 77.3 3.1 2.2 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 GAX14400.1 - 0.00044 20.4 1.4 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain MgtE PF01769.16 GAX14401.1 - 1.2e-20 74.1 6.4 1.8e-20 73.6 6.4 1.3 1 0 0 1 1 1 1 Divalent cation transporter PDCD2_C PF04194.13 GAX14402.1 - 4.2e-30 105.1 0.0 4.2e-30 105.1 0.0 2.7 3 2 1 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain HMG_box PF00505.19 GAX14403.1 - 1.2e-15 57.7 1.3 1.2e-15 57.7 1.3 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX14403.1 - 5.5e-13 49.3 4.6 8.5e-13 48.7 1.0 3.2 2 1 1 3 3 3 1 HMG-box domain LysM PF01476.20 GAX14403.1 - 8.1e-07 29.0 0.0 0.00025 21.1 0.0 2.5 2 0 0 2 2 2 2 LysM domain Acetyltransf_10 PF13673.7 GAX14403.1 - 0.00034 20.6 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX14403.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Imm58 PF15581.6 GAX14403.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 58 MMR_HSR1 PF01926.23 GAX14404.1 - 4.9e-16 58.8 0.1 1.1e-15 57.8 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAX14404.1 - 5e-06 26.7 0.0 0.067 13.2 0.0 2.2 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 GAX14404.1 - 0.00011 21.8 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAX14404.1 - 0.00012 21.7 0.0 0.0023 17.5 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX14404.1 - 0.00019 21.4 0.7 0.0083 16.0 0.1 2.5 2 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 GAX14404.1 - 0.00027 20.3 0.0 0.00053 19.3 0.0 1.5 1 1 0 1 1 1 1 Septin Roc PF08477.13 GAX14404.1 - 0.00095 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAX14404.1 - 0.0022 18.2 0.2 0.006 16.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 GAX14404.1 - 0.0037 16.7 0.0 0.0086 15.5 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_29 PF13555.6 GAX14404.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX14404.1 - 0.017 15.7 0.1 0.028 14.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 GAX14404.1 - 0.021 14.6 0.7 0.065 13.0 0.2 2.0 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Noc2 PF03715.13 GAX14405.1 - 3.2e-72 243.3 3.4 3.2e-72 243.3 3.4 2.0 2 1 0 2 2 2 1 Noc2p family Hist_deacetyl PF00850.19 GAX14406.1 - 3e-54 184.6 0.1 3.7e-54 184.3 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF3752 PF12572.8 GAX14407.1 - 3.9e-08 34.0 5.1 3.9e-08 34.0 5.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) Band_3_cyto PF07565.13 GAX14407.1 - 4.6 7.0 7.9 0.25 11.1 1.7 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Zip PF02535.22 GAX14407.1 - 6 6.0 6.2 13 4.9 6.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter ADP_ribosyl_GH PF03747.14 GAX14408.1 - 1.2e-45 156.6 0.8 1.5e-45 156.2 0.8 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Gly-zipper_Omp PF13488.6 GAX14408.1 - 0.057 13.4 3.1 0.64 10.1 0.9 2.6 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 GAX14408.1 - 0.56 10.0 5.2 1.2 9.0 5.2 1.5 1 0 0 1 1 1 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 GAX14408.1 - 0.7 9.7 5.4 0.33 10.7 2.9 1.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 GAX14408.1 - 0.79 9.6 6.6 0.36 10.7 3.4 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain NAD_Gly3P_dh_C PF07479.14 GAX14409.1 - 1.4e-43 148.6 0.1 2e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 GAX14409.1 - 6.7e-41 139.9 0.0 9.9e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 GAX14409.1 - 0.00021 21.8 0.0 0.00041 20.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 GAX14409.1 - 0.0077 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 GAX14409.1 - 0.02 14.8 0.0 0.064 13.1 0.0 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.25 GAX14409.1 - 0.04 13.3 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Whirly PF08536.11 GAX14410.1 - 0.0073 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Whirly transcription factor MS_channel PF00924.18 GAX14411.1 - 4e-26 91.8 0.0 5.4e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel LapA_dom PF06305.11 GAX14412.1 - 0.19 11.6 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PAF-AH_p_II PF03403.13 GAX14413.1 - 3.6e-28 98.2 0.0 4.6e-26 91.2 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 GAX14413.1 - 1.8e-08 34.0 0.3 0.00016 21.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAX14413.1 - 2.2e-06 27.3 0.1 5.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAX14413.1 - 1.2e-05 25.1 0.0 0.00056 19.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX14413.1 - 5.2e-05 24.0 1.7 5.2e-05 24.0 1.7 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 GAX14413.1 - 0.00045 19.9 0.0 0.0014 18.4 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 GAX14413.1 - 0.00063 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 GAX14413.1 - 0.011 14.7 0.0 0.032 13.1 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme Tannase PF07519.11 GAX14413.1 - 0.016 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase TPR_1 PF00515.28 GAX14414.1 - 6.1e-06 25.8 1.7 0.017 14.9 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14414.1 - 0.00045 20.1 1.8 0.49 10.6 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX14414.1 - 0.0067 16.6 1.9 0.26 11.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX14414.1 - 0.051 13.3 0.2 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 TPR repeat Flg_hook PF02120.16 GAX14414.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK TPR_7 PF13176.6 GAX14414.1 - 0.12 12.5 0.0 7.4 6.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX14414.1 - 0.14 12.5 0.2 0.65 10.3 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX14415.1 - 0.012 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 GAX14415.1 - 0.039 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Chromo PF00385.24 GAX14416.1 - 0.066 13.1 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain SNF2_N PF00176.23 GAX14417.1 - 9.7e-58 195.5 0.0 2.1e-57 194.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX14417.1 - 1.4e-16 60.8 0.0 3.1e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GAX14417.1 - 0.00019 20.7 0.0 0.0011 18.2 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 GAX14417.1 - 0.002 18.2 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Bromodomain PF00439.25 GAX14418.1 - 9e-16 57.7 0.0 1.9e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain LZ3wCH PF18517.1 GAX14419.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Leucine zipper with capping helix domain DOT1 PF08123.13 GAX14420.1 - 2.9e-09 36.7 0.0 4.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF3493 PF11998.8 GAX14421.1 - 3.1e-14 52.9 0.8 5.1e-14 52.2 0.8 1.4 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 DUF3117 PF11314.8 GAX14421.1 - 0.095 12.5 0.4 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) PIG-F PF06699.11 GAX14422.1 - 3.6e-06 27.3 11.4 1.3e-05 25.4 11.4 1.8 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Romo1 PF10247.9 GAX14422.1 - 0.059 13.7 0.1 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ENTH PF01417.20 GAX14423.1 - 1.5e-30 105.8 0.0 2.3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAX14423.1 - 0.063 12.3 0.0 0.063 12.3 0.0 1.6 2 0 0 2 2 2 0 ANTH domain DAO PF01266.24 GAX14424.1 - 1.2e-27 97.4 0.2 1.4e-27 97.2 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX14424.1 - 8.3e-07 28.4 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 GAX14424.1 - 0.00018 21.9 0.0 0.00037 20.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 GAX14424.1 - 0.025 15.1 0.0 0.078 13.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX14424.1 - 0.028 13.2 0.2 0.057 12.1 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 GAX14424.1 - 0.032 13.5 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX14424.1 - 0.032 13.5 0.3 0.068 12.4 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAX14424.1 - 0.13 11.6 2.1 0.17 11.1 0.2 2.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 GAX14424.1 - 0.13 12.5 0.8 0.32 11.3 0.8 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 GAX14424.1 - 0.14 12.0 0.1 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX14424.1 - 0.16 11.3 0.0 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RPAP1_N PF08621.10 GAX14425.1 - 1.5e-09 37.5 2.0 3.9e-09 36.1 2.0 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal PMSR PF01625.21 GAX14426.1 - 9.2e-15 55.1 9.1 3.7e-12 46.7 9.1 3.1 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 GAX14426.1 - 0.00029 21.1 0.0 0.00062 20.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ABC_tran PF00005.27 GAX14427.1 - 9e-39 133.1 0.0 1.3e-19 71.1 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAX14427.1 - 4.5e-13 49.7 1.3 0.031 14.1 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX14427.1 - 5.8e-11 42.2 0.0 0.048 13.1 0.0 4.5 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAX14427.1 - 6.3e-08 32.7 0.0 0.0024 17.8 0.0 2.6 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 GAX14427.1 - 3.1e-07 30.0 0.2 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX14427.1 - 2.6e-06 28.1 6.3 0.016 15.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 GAX14427.1 - 1.4e-05 25.1 0.2 0.17 11.8 0.1 2.5 2 0 0 2 2 2 2 NACHT domain Roc PF08477.13 GAX14427.1 - 2.3e-05 24.6 0.2 0.33 11.2 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAX14427.1 - 2.9e-05 24.1 1.1 0.094 12.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAX14427.1 - 5.3e-05 23.5 0.0 0.069 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GAX14427.1 - 7.5e-05 22.6 0.1 0.47 10.1 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 GAX14427.1 - 7.6e-05 22.5 2.1 0.35 10.5 0.1 3.2 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.6 GAX14427.1 - 0.00011 22.4 0.1 0.23 11.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 GAX14427.1 - 0.00015 21.5 0.1 0.67 9.7 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 GAX14427.1 - 0.00017 22.0 0.0 1 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain 4HB PF17947.1 GAX14427.1 - 0.00024 21.1 0.0 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 Four helical bundle domain NB-ARC PF00931.22 GAX14427.1 - 0.00047 19.4 0.3 0.21 10.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 GAX14427.1 - 0.00066 20.1 0.1 1.6 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 GAX14427.1 - 0.0012 18.3 0.4 0.039 13.4 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family TsaE PF02367.17 GAX14427.1 - 0.0013 18.7 3.1 0.26 11.3 0.3 2.7 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 GAX14427.1 - 0.0014 18.3 0.1 2.3 7.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAX14427.1 - 0.0018 18.8 0.0 3.4 8.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 GAX14427.1 - 0.0022 18.1 0.7 0.29 11.2 0.6 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain NTPase_1 PF03266.15 GAX14427.1 - 0.0029 17.5 0.6 1.7 8.5 0.1 2.8 3 0 0 3 3 2 1 NTPase AAA_14 PF13173.6 GAX14427.1 - 0.0033 17.5 0.0 2.6 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 GAX14427.1 - 0.0034 16.1 0.6 0.38 9.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 GAX14427.1 - 0.0044 16.7 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 GAX14427.1 - 0.0054 16.7 0.1 1.9 8.3 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea DUF3584 PF12128.8 GAX14427.1 - 0.0072 13.9 3.6 0.065 10.7 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) RNA_helicase PF00910.22 GAX14427.1 - 0.012 16.0 0.2 5.5 7.4 0.0 2.9 2 1 0 2 2 2 0 RNA helicase Septin PF00735.18 GAX14427.1 - 0.013 14.8 0.0 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 GAX14427.1 - 0.013 14.8 0.1 5 6.4 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 GAX14427.1 - 0.016 14.8 0.8 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GAX14427.1 - 0.017 15.2 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 GAX14427.1 - 0.026 14.1 1.9 1.7 8.2 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 GAX14427.1 - 0.031 13.8 3.3 0.22 11.0 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B MobB PF03205.14 GAX14427.1 - 0.031 14.2 0.3 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.22 GAX14427.1 - 0.032 13.8 0.3 7.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Ras family SbcCD_C PF13558.6 GAX14427.1 - 0.034 14.4 0.0 0.83 9.9 0.0 3.2 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 GAX14427.1 - 0.042 14.0 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAX14427.1 - 0.056 13.1 2.5 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DLIC PF05783.11 GAX14427.1 - 0.059 12.2 0.1 1.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_25 PF13481.6 GAX14427.1 - 0.083 12.5 0.3 6.7 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GAX14427.1 - 0.085 12.0 0.1 0.96 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 GAX14427.1 - 0.092 12.6 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein RuvB_N PF05496.12 GAX14427.1 - 0.13 12.0 0.3 20 4.9 0.1 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX14427.1 - 0.16 12.0 0.2 33 4.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 GAX14427.1 - 0.23 11.2 0.4 20 4.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 GAX14427.1 - 0.29 9.9 0.9 6.3 5.5 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_19 PF13245.6 GAX14427.1 - 0.29 11.5 1.0 3.3 8.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Na_H_Exchanger PF00999.21 GAX14428.1 - 1.4e-34 119.5 23.1 2e-34 119.0 23.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2207 PF09972.9 GAX14428.1 - 0.017 13.9 0.7 0.043 12.6 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) YliH PF10799.8 GAX14429.1 - 0.036 14.0 0.1 0.29 11.1 0.0 2.4 3 0 0 3 3 3 0 Biofilm formation protein (YliH/bssR) Glycos_transf_2 PF00535.26 GAX14429.1 - 0.14 12.0 0.0 2.1 8.1 0.0 2.6 2 1 1 3 3 3 0 Glycosyl transferase family 2 DUF4239 PF14023.6 GAX14430.1 - 1.2e-53 182.0 0.6 1.6e-53 181.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Mito_carr PF00153.27 GAX14431.1 - 9.2e-67 221.0 4.4 1e-21 76.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mo25 PF08569.11 GAX14432.1 - 4.7e-66 223.4 0.2 3.1e-65 220.7 0.2 1.8 1 1 0 1 1 1 1 Mo25-like Zn-C2H2_12 PF18112.1 GAX14432.1 - 0.19 12.2 1.1 0.46 11.0 1.1 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Carbam_trans_C PF16861.5 GAX14434.1 - 2.4e-62 209.5 0.0 1.1e-61 207.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 GAX14434.1 - 1.2e-28 100.7 2.6 2.2e-14 53.9 0.0 2.8 2 1 0 2 2 2 2 Carbamoyltransferase N-terminus Ribosomal_S15 PF00312.22 GAX14436.1 - 2.3e-30 104.6 1.4 4.9e-30 103.6 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 FTCD_C PF04961.12 GAX14436.1 - 0.0065 16.3 1.1 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Formiminotransferase-cyclodeaminase VWA PF00092.28 GAX14436.1 - 0.064 13.5 0.7 0.091 13.0 0.7 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Sec20 PF03908.13 GAX14436.1 - 0.066 13.1 1.4 0.11 12.4 0.3 1.9 1 1 1 2 2 2 0 Sec20 F-box PF00646.33 GAX14437.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 GAX14437.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like Eapp_C PF10238.9 GAX14437.1 - 4 7.5 6.2 1.4 9.0 0.2 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein Sec1 PF00995.23 GAX14438.1 - 2.7e-107 360.4 0.1 3.1e-107 360.2 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Leu_Phe_trans PF03588.14 GAX14439.1 - 5.4e-26 91.1 0.0 8.6e-26 90.5 0.0 1.3 1 1 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase DXP_reductoisom PF02670.16 GAX14440.1 - 6.6e-41 140.0 2.3 1.2e-40 139.2 2.3 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 GAX14440.1 - 4.8e-36 123.5 0.0 8.9e-36 122.7 0.0 1.5 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 GAX14440.1 - 2.3e-35 120.6 0.0 6.1e-35 119.2 0.0 1.8 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain CDP-OH_P_transf PF01066.21 GAX14441.1 - 1.4e-05 25.8 0.1 1.4e-05 25.8 0.1 2.8 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase 6PF2K PF01591.18 GAX14442.1 - 7.6e-57 192.2 0.1 2.3e-31 108.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAX14442.1 - 5e-16 59.0 0.0 1.6e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAX14442.1 - 5.6e-05 23.3 0.1 0.00086 19.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 GAX14442.1 - 0.0039 16.7 0.1 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 WD40 PF00400.32 GAX14444.1 - 5e-07 30.3 1.5 0.0014 19.4 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX14444.1 - 8.6e-07 29.2 0.0 0.00029 21.1 0.0 3.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_C PF00137.21 GAX14446.1 - 1.9e-26 92.1 23.1 3.3e-16 59.4 8.9 2.4 2 0 0 2 2 2 2 ATP synthase subunit C FF PF01846.19 GAX14447.1 - 5.1e-20 71.4 26.7 2.9e-07 30.5 1.9 5.7 5 1 0 5 5 5 4 FF domain WW PF00397.26 GAX14447.1 - 7.5e-09 35.5 17.4 2.5e-07 30.7 2.3 3.6 2 1 0 2 2 2 2 WW domain Mating_N PF12731.7 GAX14447.1 - 0.15 12.2 3.6 0.17 12.0 0.3 2.6 1 1 2 3 3 3 0 Mating-type protein beta 1 PAP_assoc PF03828.19 GAX14448.1 - 0.0008 19.6 0.0 0.0024 18.0 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAX14448.1 - 0.02 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain MarB PF13999.6 GAX14448.1 - 0.95 9.4 3.5 1.1 9.1 1.3 2.2 2 0 0 2 2 2 0 MarB protein HCO3_cotransp PF00955.21 GAX14449.1 - 2.7e-108 363.0 17.7 2e-62 211.7 5.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family BEN PF10523.9 GAX14450.1 - 0.0093 16.2 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 BEN domain Indigoidine_A PF04227.12 GAX14451.1 - 4.8e-113 377.3 1.4 6.8e-113 376.9 1.4 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 GAX14451.1 - 2.8e-31 109.0 0.0 1.6e-30 106.5 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RNase_T PF00929.24 GAX14452.1 - 3.4e-11 43.9 0.0 6.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease His_Phos_1 PF00300.22 GAX14453.1 - 5e-10 39.4 0.0 0.0025 17.5 0.0 3.4 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Cyclin PF08613.11 GAX14454.1 - 3.9e-05 24.1 0.0 6.6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAX14454.1 - 0.00015 21.5 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 GAX14455.1 - 1.4e-44 152.5 0.0 4.3e-44 150.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14455.1 - 1.3e-42 145.9 0.0 2e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YukC PF10140.9 GAX14455.1 - 0.0011 17.9 0.1 0.0016 17.3 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC PIP49_C PF12260.8 GAX14455.1 - 0.081 12.6 0.0 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 B2 PF11473.8 GAX14455.1 - 0.13 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein B2 adh_short PF00106.25 GAX14456.1 - 1.4e-27 96.4 0.2 2.1e-27 95.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX14456.1 - 6.1e-24 84.9 0.1 8.5e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAX14456.1 - 0.00012 21.6 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX14456.1 - 0.00046 20.1 0.2 0.00063 19.7 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAX14456.1 - 0.0011 19.0 0.3 0.0032 17.4 0.1 1.9 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 GAX14456.1 - 0.009 15.1 0.3 0.019 14.1 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 GAX14456.1 - 0.012 14.9 0.1 0.032 13.6 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 GAX14456.1 - 0.092 12.1 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 ThiF family ADH_zinc_N PF00107.26 GAX14456.1 - 0.13 12.3 0.2 0.3 11.1 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ABC_tran PF00005.27 GAX14457.1 - 9.1e-50 168.7 0.0 2.4e-27 96.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAX14457.1 - 1.3e-45 156.1 21.4 7.5e-26 91.4 3.7 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 GAX14457.1 - 2e-12 47.1 0.2 1.4e-06 27.9 0.1 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX14457.1 - 8.1e-06 26.2 0.4 0.28 11.4 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAX14457.1 - 1.4e-05 25.1 1.6 0.38 10.5 0.1 3.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX14457.1 - 4.1e-05 23.3 1.3 0.24 11.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAX14457.1 - 4.5e-05 23.5 0.4 0.36 10.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX14457.1 - 0.00025 21.5 2.2 0.64 10.4 0.3 3.2 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 GAX14457.1 - 0.0023 18.0 2.5 0.044 13.9 0.2 2.5 2 0 0 2 2 2 1 Dynamin family DUF815 PF05673.13 GAX14457.1 - 0.0047 16.1 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF87 PF01935.17 GAX14457.1 - 0.01 16.0 3.2 1.3 9.1 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 GAX14457.1 - 0.012 15.5 0.9 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 GAX14457.1 - 0.015 14.6 1.6 4.9 6.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 GAX14457.1 - 0.023 14.2 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAX14457.1 - 0.045 13.0 0.2 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 GAX14457.1 - 0.052 14.0 0.2 14 6.1 0.0 3.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 GAX14457.1 - 0.063 12.9 0.6 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 GAX14457.1 - 0.071 12.0 0.6 5.5 5.8 0.0 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 GAX14457.1 - 0.072 13.6 1.9 5.5 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX14457.1 - 0.087 13.4 0.1 1.8 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAX14457.1 - 0.13 11.3 0.1 13 4.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.7 GAX14457.1 - 0.14 11.1 0.6 51 2.6 0.1 3.0 3 0 0 3 3 3 0 AAA-like domain AAA_15 PF13175.6 GAX14457.1 - 0.22 11.2 0.6 6.5 6.4 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.12 GAX14457.1 - 0.26 10.7 0.4 6.6 6.1 0.3 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein SMC_N PF02463.19 GAX14458.1 - 2.4e-72 242.9 20.5 3.9e-71 239.0 20.5 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAX14458.1 - 7.7e-25 87.5 0.0 2.5e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 GAX14458.1 - 1.9e-16 60.8 2.9 1.9e-16 60.8 2.9 4.1 2 2 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 GAX14458.1 - 8.1e-14 52.6 9.3 8.1e-14 52.6 9.3 7.3 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 GAX14458.1 - 2.1e-13 50.8 0.0 6.2e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX14458.1 - 8e-07 28.7 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX14458.1 - 0.0028 18.1 10.7 0.044 14.3 0.0 4.9 3 1 0 3 3 3 2 ABC transporter Baculo_PEP_C PF04513.12 GAX14458.1 - 0.0087 16.1 15.1 0.42 10.6 0.1 5.2 4 2 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 GAX14458.1 - 0.093 13.0 0.0 18 5.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain Flu_M1_C PF08289.11 GAX14458.1 - 3.5 7.9 7.5 1.5 9.0 2.2 3.3 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain Adenine_glyco PF03352.13 GAX14459.1 - 1.6e-58 197.4 0.0 2.4e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Methyladenine glycosylase DFF-C PF09033.10 GAX14459.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Methyltransf_11 PF08241.12 GAX14460.1 - 2.6e-23 82.5 0.0 4.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX14460.1 - 8.4e-23 80.9 0.0 1.7e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX14460.1 - 1.8e-20 73.2 0.0 3e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX14460.1 - 3.2e-16 59.6 0.0 5.4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX14460.1 - 4.5e-16 58.9 0.0 8.9e-16 57.9 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX14460.1 - 1.1e-15 58.1 0.0 2.5e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX14460.1 - 4.5e-12 45.8 0.0 6.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 GAX14460.1 - 1.1e-09 37.5 0.0 1.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 GAX14460.1 - 6.6e-07 29.3 0.0 9.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 GAX14460.1 - 0.00024 21.3 0.0 0.0015 18.6 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 GAX14460.1 - 0.0021 17.6 0.0 0.0045 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 GAX14460.1 - 0.0024 17.3 0.0 0.0055 16.1 0.0 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 GAX14460.1 - 0.0034 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAX14460.1 - 0.0043 16.7 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 GAX14460.1 - 0.0051 16.7 0.0 0.0098 15.8 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 GAX14460.1 - 0.0068 15.9 0.0 0.063 12.7 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.6 GAX14460.1 - 0.022 15.8 0.0 0.038 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAS PF03059.16 GAX14460.1 - 0.043 13.1 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein ADH_zinc_N PF00107.26 GAX14460.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_20 PF12147.8 GAX14460.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Hydrolase_4 PF12146.8 GAX14461.1 - 1.7e-12 47.1 0.0 3.3e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX14461.1 - 6.1e-09 36.8 0.6 2.7e-07 31.4 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX14461.1 - 2.3e-07 30.8 0.0 0.0007 19.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 GAX14461.1 - 0.00014 20.6 0.0 0.083 11.5 0.0 2.4 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 GAX14461.1 - 0.00022 21.1 0.0 0.00068 19.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX14461.1 - 0.00056 19.5 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAX14461.1 - 0.023 14.5 0.0 1.7 8.4 0.0 3.1 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase DLH PF01738.18 GAX14461.1 - 0.033 13.8 0.0 4.3 6.8 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family BAAT_C PF08840.11 GAX14461.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.12 GAX14461.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 FSH1 PF03959.13 GAX14461.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 GAX14461.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain UDPG_MGDP_dh_N PF03721.14 GAX14462.1 - 1.6e-60 203.9 0.2 2.4e-60 203.3 0.2 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 GAX14462.1 - 1.3e-32 112.3 0.3 1.1e-31 109.3 0.1 2.5 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 GAX14462.1 - 9.3e-31 105.9 0.0 2e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 GAX14462.1 - 0.0022 18.2 0.1 0.0071 16.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX14462.1 - 0.052 13.8 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LRV_FeS PF05484.11 GAX14462.1 - 0.075 13.1 0.1 17 5.5 0.0 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster Peptidase_M50 PF02163.22 GAX14463.1 - 3.3e-05 23.3 5.4 0.027 13.8 0.3 3.1 2 1 1 3 3 3 2 Peptidase family M50 Ferritin_2 PF13668.6 GAX14463.1 - 0.12 12.6 0.0 0.75 10.0 0.0 2.2 2 0 0 2 2 2 0 Ferritin-like domain IBD PF10416.9 GAX14464.1 - 0.021 14.9 1.1 3.4 7.7 0.3 2.5 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD CENP-O PF09496.10 GAX14465.1 - 0.083 12.9 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component ORC3_N PF07034.11 GAX14465.1 - 0.18 10.8 0.6 0.3 10.1 0.6 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus 2OG-FeII_Oxy_3 PF13640.6 GAX14469.1 - 1.7e-09 38.4 0.0 2.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX14469.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily APOBEC_N PF08210.11 GAX14471.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Tcp10_C PF07202.13 GAX14471.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Ank_5 PF13857.6 GAX14472.1 - 1.1e-09 38.3 0.1 3.8e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX14472.1 - 1e-07 32.4 0.0 8e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX14472.1 - 1.4e-06 28.7 0.1 1.6e-05 25.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 GAX14472.1 - 1.4e-05 25.8 0.0 2.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-RING_5 PF14634.6 GAX14472.1 - 3.7e-05 23.6 6.3 0.00015 21.7 6.3 2.1 1 0 0 1 1 1 1 zinc-RING finger domain Ank PF00023.30 GAX14472.1 - 0.00016 22.0 0.0 0.001 19.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat zf-RING_2 PF13639.6 GAX14472.1 - 0.0012 19.1 9.0 0.0012 19.1 9.0 3.3 3 0 0 3 3 3 1 Ring finger domain CEBP_ZZ PF16366.5 GAX14472.1 - 0.005 17.0 3.2 0.005 17.0 3.2 2.9 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Ank_3 PF13606.6 GAX14472.1 - 0.006 17.0 0.0 0.45 11.2 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat zf-RING_UBOX PF13445.6 GAX14472.1 - 0.9 9.6 10.0 0.36 10.9 6.2 2.5 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX14472.1 - 3.1 7.7 12.4 28 4.7 11.6 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FGGY_N PF00370.21 GAX14474.1 - 1.9e-07 30.9 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAX14474.1 - 0.00043 20.1 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Headcase PF16002.5 GAX14474.1 - 0.056 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Headcase protein RNase_T PF00929.24 GAX14475.1 - 1.8e-06 28.6 0.2 3.3e-06 27.8 0.2 1.4 1 0 0 1 1 1 1 Exonuclease zf-CCCH_4 PF18044.1 GAX14475.1 - 3.9e-05 23.3 1.2 7.7e-05 22.4 1.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 GAX14475.1 - 8.7e-05 22.3 1.9 0.00019 21.3 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 GAX14475.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GAX14475.1 - 0.013 15.6 3.5 0.035 14.2 3.5 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 GAX14475.1 - 0.12 12.9 2.5 0.31 11.6 2.5 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Beta_helix PF13229.6 GAX14476.1 - 0.00024 21.0 3.4 0.00087 19.2 3.4 1.8 1 1 0 1 1 1 1 Right handed beta helix region PT PF04886.12 GAX14476.1 - 0.065 12.8 15.8 1.4 8.5 4.8 2.7 1 1 1 2 2 2 0 PT repeat Pkinase PF00069.25 GAX14477.1 - 4.9e-35 121.2 0.2 5.7e-20 71.8 0.0 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14477.1 - 6.1e-12 45.4 0.6 0.00011 21.6 0.3 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase Peptidase_S49_N PF08496.10 GAX14477.1 - 0.82 9.7 6.3 0.078 13.0 1.2 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Actin PF00022.19 GAX14478.1 - 2.5e-112 375.5 0.0 1.5e-111 373.0 0.0 1.8 1 1 0 1 1 1 1 Actin EcoRII-C PF09019.11 GAX14478.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 EcoRII C terminal HSF_DNA-bind PF00447.17 GAX14479.1 - 2.9e-10 40.6 0.7 5.7e-10 39.7 0.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_S18 PF01084.20 GAX14480.1 - 3e-14 53.0 1.3 4.1e-14 52.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 CASP_C PF08172.12 GAX14481.1 - 1.3e-53 182.0 7.8 1.3e-53 182.0 7.8 3.9 3 1 1 4 4 4 1 CASP C terminal DUF1664 PF07889.12 GAX14481.1 - 0.0029 17.6 0.5 0.0029 17.6 0.5 6.6 4 1 4 8 8 8 1 Protein of unknown function (DUF1664) Syntaxin-18_N PF10496.9 GAX14481.1 - 0.0033 17.6 0.5 0.0033 17.6 0.5 3.1 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Cortex-I_coil PF09304.10 GAX14481.1 - 0.0044 17.2 6.8 0.0044 17.2 6.8 6.6 5 2 2 8 8 8 1 Cortexillin I, coiled coil HEAT_2 PF13646.6 GAX14482.1 - 0.052 13.9 2.5 2.8 8.4 0.6 3.6 2 1 0 2 2 2 0 HEAT repeats Na_Pi_cotrans PF02690.15 GAX14483.1 - 2.4e-38 131.4 21.1 3.7e-19 69.2 7.3 2.5 2 0 0 2 2 2 2 Na+/Pi-cotransporter DUF4381 PF14316.6 GAX14483.1 - 1.5 9.1 4.2 0.87 9.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) RTT107_BRCT_5 PF16770.5 GAX14484.1 - 6.1e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 GAX14484.1 - 0.001 19.4 0.0 0.013 15.9 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAX14484.1 - 0.017 15.1 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 GAX14484.1 - 0.017 15.5 0.1 0.085 13.3 0.1 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Pep3_Vps18 PF05131.14 GAX14485.1 - 1.4e-13 51.0 0.1 2.1e-12 47.1 0.1 2.4 1 1 0 1 1 1 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 GAX14485.1 - 0.17 12.4 0.0 0.73 10.3 0.0 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-Tim10_DDP PF02953.15 GAX14486.1 - 3.1e-15 55.6 6.8 4.3e-15 55.1 6.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF775 PF05603.12 GAX14486.1 - 0.034 13.7 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Mitoc_L55 PF09776.9 GAX14486.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Gluconate_2-dh3 PF13618.6 GAX14486.1 - 0.088 13.0 0.6 0.17 12.1 0.2 1.6 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Calici_MSP PF05752.11 GAX14486.1 - 0.11 12.3 4.6 1.7 8.4 1.1 2.0 1 1 1 2 2 2 0 Calicivirus minor structural protein 7tm_3 PF00003.22 GAX14488.1 - 1.1e-32 113.7 12.6 1.6e-32 113.2 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 5_nucleotid_C PF02872.18 GAX14488.1 - 4.4e-23 82.2 0.0 1.1e-22 80.9 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain AARP2CN PF08142.12 GAX14489.1 - 8.5e-27 93.1 0.0 8.5e-27 93.1 0.0 3.0 3 1 0 3 3 2 1 AARP2CN (NUC121) domain RIBIOP_C PF04950.12 GAX14489.1 - 6.5e-26 91.4 0.9 1.7e-25 90.1 0.0 2.1 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AAA_22 PF13401.6 GAX14489.1 - 5.2e-06 26.8 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 GAX14489.1 - 2e-05 24.2 0.4 0.0021 17.7 0.0 2.8 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 GAX14489.1 - 0.00011 22.3 0.0 0.00032 20.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 GAX14489.1 - 0.00012 22.1 0.8 0.00036 20.6 0.1 2.3 2 0 0 2 2 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX14489.1 - 0.00015 22.2 0.0 0.00089 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 GAX14489.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAX14489.1 - 0.0023 17.9 0.1 0.0065 16.4 0.0 1.8 2 0 0 2 2 1 1 RsgA GTPase ABC_tran PF00005.27 GAX14489.1 - 0.0027 18.2 1.3 0.0063 17.0 0.0 2.3 2 0 0 2 2 1 1 ABC transporter AAA_5 PF07728.14 GAX14489.1 - 0.003 17.6 0.1 0.0069 16.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 GAX14489.1 - 0.0037 17.7 0.1 0.011 16.1 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAX14489.1 - 0.0053 17.3 0.3 0.0053 17.3 0.3 2.9 4 0 0 4 4 1 1 AAA domain Viral_helicase1 PF01443.18 GAX14489.1 - 0.009 15.8 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 GAX14489.1 - 0.01 15.8 0.2 0.064 13.2 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAX14489.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAX14489.1 - 0.012 16.0 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 GAX14489.1 - 0.013 15.4 0.9 0.031 14.2 0.9 1.6 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 GAX14489.1 - 0.015 14.8 1.4 0.26 10.8 0.2 2.3 1 1 1 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 GAX14489.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 GAX14489.1 - 0.027 14.7 0.1 0.07 13.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAX14489.1 - 0.039 14.0 0.8 0.64 10.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAX14489.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 GAX14489.1 - 0.05 13.4 0.1 0.21 11.3 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 GAX14489.1 - 0.051 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 GAX14489.1 - 0.053 13.1 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 GAX14489.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Ploopntkinase3 PF18751.1 GAX14489.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 GAX14489.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 GAX14489.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 GAX14489.1 - 0.11 12.7 0.1 0.33 11.2 0.1 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RNA12 PF10443.9 GAX14489.1 - 0.12 11.0 0.0 0.12 11.0 0.0 2.8 2 1 0 2 2 1 0 RNA12 protein T2SSE PF00437.20 GAX14489.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 GAX14489.1 - 0.37 11.2 0.0 0.37 11.2 0.0 4.2 5 1 0 5 5 4 0 AAA domain DZF PF07528.14 GAX14490.1 - 0.044 13.4 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 DZF domain zf-RING_2 PF13639.6 GAX14491.1 - 4.3e-11 42.9 9.6 6.9e-11 42.3 9.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX14491.1 - 2.6e-06 27.0 2.0 2.6e-06 27.0 2.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX14491.1 - 8.1e-06 25.6 8.6 1.3e-05 24.9 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX14491.1 - 1.2e-05 25.4 9.4 2.6e-05 24.4 9.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX14491.1 - 1.3e-05 24.9 9.1 2e-05 24.3 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX14491.1 - 0.0001 22.3 5.2 0.00024 21.1 5.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 GAX14491.1 - 0.00012 21.9 6.3 0.012 15.6 1.3 2.2 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-Nse PF11789.8 GAX14491.1 - 0.00056 19.7 3.9 0.0011 18.8 3.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 GAX14491.1 - 0.0022 18.0 3.8 0.0061 16.6 3.9 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX14491.1 - 0.0029 17.5 7.5 0.0045 16.9 7.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain YdjO PF14169.6 GAX14491.1 - 0.013 15.2 0.7 1.2 8.9 0.2 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO RINGv PF12906.7 GAX14491.1 - 0.017 15.3 9.5 0.027 14.6 9.5 1.4 1 0 0 1 1 1 0 RING-variant domain CENP-T_C PF15511.6 GAX14491.1 - 0.045 13.9 0.1 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PHD PF00628.29 GAX14491.1 - 0.088 12.7 8.3 0.16 11.9 8.3 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 GAX14491.1 - 0.099 12.3 5.2 0.19 11.4 5.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 GAX14491.1 - 0.11 12.4 6.6 0.21 11.5 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3911 PF13050.6 GAX14491.1 - 0.13 12.4 0.1 20 5.3 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3911) FANCL_C PF11793.8 GAX14491.1 - 0.17 12.1 8.7 0.72 10.1 8.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 GAX14491.1 - 0.33 11.1 5.2 0.65 10.2 5.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 GAX14491.1 - 0.42 10.9 7.3 0.99 9.8 7.3 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 GAX14491.1 - 0.49 10.2 8.8 0.83 9.5 8.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CTU2 PF10288.9 GAX14491.1 - 1.9 8.8 5.7 40 4.5 5.7 2.2 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Ribosomal_L5e PF17144.4 GAX14492.1 - 4.2e-81 270.7 1.6 4.2e-81 270.7 1.6 1.8 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GAX14492.1 - 4.3e-30 104.5 3.2 4.3e-30 104.5 3.2 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region PAZ PF02170.22 GAX14492.1 - 0.0042 16.9 1.3 0.0059 16.4 0.0 1.9 2 0 0 2 2 2 1 PAZ domain TMEM18 PF14770.6 GAX14493.1 - 3.5e-37 127.0 3.5 4.6e-37 126.6 3.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 NrfD PF03916.14 GAX14493.1 - 0.0044 16.7 2.2 0.0059 16.3 2.2 1.1 1 0 0 1 1 1 1 Polysulphide reductase, NrfD Macro PF01661.21 GAX14494.1 - 2.4e-18 66.3 0.0 6.7e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 Macro domain DNA_methylase PF00145.17 GAX14495.1 - 2.1e-32 112.8 0.0 2.5e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNA_repr_REX1B PF14966.6 GAX14496.1 - 8.5e-26 90.5 1.7 8.5e-26 90.5 1.7 1.9 1 1 0 1 1 1 1 DNA repair REX1-B DUF1690 PF07956.11 GAX14496.1 - 0.0078 16.6 8.5 0.02 15.3 1.1 2.2 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Tox-GHH PF15636.6 GAX14496.1 - 0.069 13.1 1.0 0.97 9.5 0.1 2.7 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin K-box PF01486.17 GAX14496.1 - 0.17 12.1 10.3 0.49 10.6 2.7 3.2 2 1 1 3 3 3 0 K-box region Ion_trans_2 PF07885.16 GAX14497.1 - 2e-14 53.3 22.8 2.8e-08 33.6 1.1 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 GAX14497.1 - 0.00045 19.5 9.6 0.003 16.8 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein Clr5 PF14420.6 GAX14497.1 - 0.16 12.2 0.5 0.53 10.6 0.2 2.0 2 0 0 2 2 2 0 Clr5 domain Rpn3_C PF08375.11 GAX14498.1 - 6.4e-24 84.2 1.9 8.1e-24 83.8 0.7 1.8 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 GAX14498.1 - 2.2e-15 57.0 0.0 7.8e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain RRM_1 PF00076.22 GAX14499.1 - 1.2e-55 185.2 0.3 5.6e-21 74.1 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX14499.1 - 1.6e-08 34.5 0.1 0.018 15.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 GAX14499.1 - 0.024 14.6 0.0 1.5 8.9 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Nab6_mRNP_bdg PF10567.9 GAX14499.1 - 0.05 13.1 0.0 1.9 7.9 0.0 2.3 1 1 1 2 2 2 0 RNA-recognition motif RNA_bind PF08675.11 GAX14499.1 - 0.14 12.2 0.0 26 4.9 0.0 3.3 3 0 0 3 3 3 0 RNA binding domain PHM7_cyt PF14703.6 GAX14499.1 - 0.33 11.2 2.5 9.7 6.4 0.1 3.6 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter LPMO_10 PF03067.15 GAX14500.1 - 2.4e-21 77.3 0.3 3.3e-21 76.8 0.3 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading HSF_DNA-bind PF00447.17 GAX14501.1 - 1.8e-23 82.9 0.3 5e-23 81.5 0.1 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Tup_N PF08581.10 GAX14501.1 - 0.06 13.6 1.1 0.06 13.6 1.1 1.7 1 1 0 1 1 1 0 Tup N-terminal CRAL_TRIO PF00650.20 GAX14502.1 - 1.4e-20 73.6 0.0 2.1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain PfkB PF00294.24 GAX14503.1 - 3.3e-25 89.0 0.0 6.7e-25 88.0 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase TIM PF00121.18 GAX14504.1 - 9.7e-85 283.8 0.0 1.2e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase SGL PF08450.12 GAX14504.1 - 1.7e-28 99.8 0.0 2.3e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NAD_binding_2 PF03446.15 GAX14506.1 - 3e-28 99.0 1.5 5.4e-28 98.2 1.5 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAX14506.1 - 7.4e-24 84.3 0.1 2e-23 82.9 0.1 1.8 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAX14506.1 - 1.1e-07 32.3 0.6 3e-07 30.9 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GAX14506.1 - 1.9e-05 24.7 0.5 5.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX14506.1 - 0.12 12.7 0.2 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DHQ_synthase PF01761.20 GAX14507.1 - 5.1e-60 202.9 0.0 7.6e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 GAX14507.1 - 1.8e-09 37.7 0.0 8.3e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 GAX14507.1 - 2.1e-05 23.5 0.0 0.00028 19.8 0.0 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase CS PF04969.16 GAX14509.1 - 4.8e-09 37.1 0.0 8.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 CS domain Cwf_Cwc_15 PF04889.12 GAX14509.1 - 0.0069 16.2 1.6 0.0087 15.8 1.6 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 GAX14509.1 - 0.024 12.7 5.5 0.03 12.4 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Forkhead_N PF08430.12 GAX14509.1 - 0.28 11.8 12.8 0.45 11.1 12.8 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region CNDH2_M PF16869.5 GAX14509.1 - 1.5 9.5 9.1 2.3 8.9 4.5 2.0 2 0 0 2 2 2 0 PF16858 YjeF_N PF03853.15 GAX14510.1 - 8.9e-37 126.6 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PI3_PI4_kinase PF00454.27 GAX14510.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase TIM21 PF08294.11 GAX14511.1 - 1.4e-12 47.7 0.1 2e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 TIM21 YjeF_N PF03853.15 GAX14512.1 - 1.5e-35 122.6 0.0 2.1e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus STAS PF01740.21 GAX14513.1 - 9.4e-12 44.6 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 GAX14513.1 - 2.5e-05 23.2 3.7 2.5e-05 23.2 3.7 2.6 2 1 0 2 2 2 2 Sulfate permease family STAS_2 PF13466.6 GAX14513.1 - 7.6e-05 23.0 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 STAS domain DUF3180 PF11377.8 GAX14513.1 - 1.9 8.6 13.8 0.034 14.3 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) CoxIIa PF08113.11 GAX14513.1 - 3.4 7.6 6.8 0.21 11.4 0.6 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family RRM_3 PF08777.11 GAX14514.1 - 0.0078 16.2 0.0 0.063 13.3 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Sm_like PF16243.5 GAX14514.1 - 0.018 15.2 0.2 0.19 11.9 0.1 2.4 2 0 0 2 2 2 0 Sm_like domain RabGAP-TBC PF00566.18 GAX14515.1 - 9.3e-30 103.9 0.9 5.9e-29 101.3 0.8 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CAP_N PF01213.19 GAX14515.1 - 0.55 9.7 14.8 0.15 11.6 3.4 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NDK PF00334.19 GAX14516.1 - 4.8e-54 182.0 0.0 5.7e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Mago_nashi PF02792.14 GAX14517.1 - 0.088 12.9 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Mago nashi protein Med2 PF11214.8 GAX14517.1 - 0.29 11.3 2.2 0.59 10.3 2.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 Chibby PF14645.6 GAX14518.1 - 0.12 12.8 0.0 0.84 10.1 0.0 2.2 2 0 0 2 2 2 0 Chibby family CPSF_A PF03178.15 GAX14519.1 - 1.7e-53 182.0 0.0 4.7e-53 180.6 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region adh_short PF00106.25 GAX14520.1 - 7.9e-26 90.7 0.0 1.4e-21 76.9 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX14520.1 - 3.1e-12 46.5 0.0 1e-10 41.6 0.0 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX14520.1 - 1.9e-06 27.9 0.1 3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 KR domain zf-HC5HC2H_2 PF13832.6 GAX14521.1 - 0.053 13.7 4.2 9.8 6.4 0.1 4.0 4 0 0 4 4 4 0 PHD-zinc-finger like domain TB PF00683.17 GAX14521.1 - 4.8 7.0 10.9 6.9 6.5 0.0 4.2 4 0 0 4 4 4 0 TB domain adh_short PF00106.25 GAX14522.1 - 4e-29 101.5 0.0 5.6e-23 81.4 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX14522.1 - 2.4e-15 56.7 0.0 1.9e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX14522.1 - 7e-10 39.1 0.7 2.1e-09 37.5 0.2 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAX14522.1 - 0.002 17.3 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAX14522.1 - 0.0095 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 GAX14522.1 - 0.042 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LEA_5 PF00477.17 GAX14522.1 - 0.18 12.3 0.7 0.77 10.2 0.2 2.0 2 0 0 2 2 2 0 Small hydrophilic plant seed protein DSPc PF00782.20 GAX14523.1 - 1.4e-20 73.5 0.1 1.7e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DMA PF03474.14 GAX14523.1 - 0.0058 16.2 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 DMRTA motif Y_phosphatase PF00102.27 GAX14523.1 - 0.0096 15.5 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DDR_swiveling PF18427.1 GAX14523.1 - 0.068 13.2 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain UBA PF00627.31 GAX14523.1 - 0.08 12.9 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 UBA/TS-N domain TIM PF00121.18 GAX14524.1 - 1.9e-84 282.9 0.0 2.3e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase Ofd1_CTDD PF10637.9 GAX14525.1 - 7.6e-66 222.1 0.0 4.3e-61 206.5 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 GAX14525.1 - 1.9e-22 79.7 0.0 5.8e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAX14525.1 - 3.2e-15 56.8 0.0 1.5e-14 54.6 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FAD_binding_2 PF00890.24 GAX14526.1 - 1.9e-122 409.4 5.6 2.6e-122 408.9 5.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAX14526.1 - 6.5e-45 152.2 0.7 9.8e-45 151.7 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 GAX14526.1 - 0.00013 21.3 0.7 0.03 13.6 0.1 2.7 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 GAX14526.1 - 0.00042 19.5 1.9 0.11 11.5 1.7 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAX14526.1 - 0.00044 19.6 0.9 0.011 15.0 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX14526.1 - 0.0039 16.5 0.3 0.0039 16.5 0.3 2.2 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 GAX14526.1 - 0.011 15.3 0.4 0.039 13.5 0.3 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX14526.1 - 0.41 9.3 2.3 0.89 8.2 0.6 2.3 3 0 0 3 3 3 0 HI0933-like protein EF-hand_7 PF13499.6 GAX14527.1 - 1.1e-16 61.0 3.9 2.9e-10 40.4 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX14527.1 - 5e-12 44.7 3.5 4.8e-07 29.2 0.1 4.1 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 GAX14527.1 - 3.5e-10 38.7 10.2 2.3e-07 29.9 0.1 4.6 4 2 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAX14527.1 - 3.4e-07 30.0 4.2 0.00058 19.7 0.7 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX14527.1 - 7.4e-07 28.4 0.0 7.4e-07 28.4 0.0 3.2 6 0 0 6 6 6 1 EF hand EF-hand_9 PF14658.6 GAX14527.1 - 0.00035 20.8 0.0 0.3 11.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain PI-TkoII_IV PF18714.1 GAX14527.1 - 0.015 14.7 0.2 0.026 14.0 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV EFhand_Ca_insen PF08726.10 GAX14527.1 - 0.056 13.5 0.7 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.13 GAX14527.1 - 0.071 13.1 0.0 8.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Yop-YscD_cpl PF16697.5 GAX14529.1 - 0.0011 19.2 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 GAX14529.1 - 0.0019 18.5 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain HSF_DNA-bind PF00447.17 GAX14530.1 - 4.8e-29 100.8 1.5 1.3e-28 99.5 1.5 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding FlaC_arch PF05377.11 GAX14530.1 - 0.34 11.3 4.0 0.9 10.0 4.0 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MutS_V PF00488.21 GAX14531.1 - 6.9e-07 29.5 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain V AAA_23 PF13476.6 GAX14531.1 - 0.22 12.0 0.5 0.79 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.8 GAX14532.1 - 4e-10 39.4 0.7 1.6e-05 24.3 0.6 2.9 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX14532.1 - 3e-06 28.0 0.9 4.6e-06 27.4 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 GAX14532.1 - 1.7e-05 23.9 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 GAX14532.1 - 0.0022 17.7 0.8 0.0084 15.8 0.1 2.1 2 1 1 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.18 GAX14532.1 - 0.0037 16.9 0.0 0.0074 15.9 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 GAX14532.1 - 0.019 14.6 0.2 0.06 13.0 0.2 1.7 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 GAX14532.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.13 GAX14532.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Thioesterase PF00975.20 GAX14532.1 - 0.086 12.9 0.1 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain ketoacyl-synt PF00109.26 GAX14534.1 - 0.2 11.2 0.1 0.31 10.6 0.1 1.3 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain HSP90 PF00183.18 GAX14535.1 - 1.5e-108 364.0 0.8 3.3e-103 346.3 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 GAX14535.1 - 5.5e-09 36.0 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAX14535.1 - 2.6e-07 31.1 0.2 4.9e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.27 GAX14536.1 - 9.1e-67 221.1 1.2 3.9e-21 74.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EutK_C PF16365.5 GAX14536.1 - 0.001 19.1 0.0 0.15 12.1 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilization protein EutK C-terminus Serine_protease PF18405.1 GAX14536.1 - 0.017 14.3 0.3 1.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Phage_holin_3_1 PF05106.12 GAX14536.1 - 0.16 12.4 0.3 16 6.0 0.0 2.8 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) DUF3082 PF11282.8 GAX14538.1 - 3.5e-21 75.2 5.8 5.8e-21 74.5 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) BON PF04972.17 GAX14538.1 - 0.045 14.1 0.3 0.12 12.7 0.3 1.6 1 0 0 1 1 1 0 BON domain CS PF04969.16 GAX14539.1 - 1e-15 58.5 0.2 3.1e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.6 GAX14539.1 - 4.1e-12 45.9 0.0 7.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Trp_syntA PF00290.20 GAX14540.1 - 1.6e-83 279.5 0.2 3e-83 278.6 0.2 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 GAX14540.1 - 5.7e-47 160.5 4.3 5.8e-47 160.5 2.3 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 GAX14540.1 - 0.002 17.6 0.0 0.0083 15.6 0.0 2.0 2 1 0 2 2 2 1 Histidine biosynthesis protein DUF1971 PF09313.11 GAX14540.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) DUF2547 PF10818.8 GAX14541.1 - 0.12 13.3 0.0 0.13 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Mago_nashi PF02792.14 GAX14542.1 - 7.1e-50 168.8 0.0 7.9e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein Skp1_POZ PF03931.15 GAX14543.1 - 4e-10 39.7 0.4 7.4e-10 38.9 0.4 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 GAX14543.1 - 1.4e-08 34.7 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain PUA_3 PF17785.1 GAX14543.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 PUA-like domain Skp1 PF01466.19 GAX14544.1 - 2.5e-13 49.9 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAX14544.1 - 7e-08 32.5 0.1 1.9e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain PFO_beta_C PF12367.8 GAX14544.1 - 0.073 13.2 0.3 0.14 12.3 0.3 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Pkinase PF00069.25 GAX14545.1 - 1.4e-27 96.7 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14545.1 - 2.7e-11 43.3 0.0 3.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAF-AH_p_II PF03403.13 GAX14546.1 - 6.8e-08 31.4 0.0 1e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GAX14546.1 - 1.8e-05 23.8 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 GAX14546.1 - 5.7e-05 23.8 0.2 8.4e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 GAX14546.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase EMP70 PF02990.16 GAX14547.1 - 7.2e-101 338.4 18.7 1e-67 229.0 18.0 2.3 2 0 0 2 2 2 2 Endomembrane protein 70 PLAC8 PF04749.17 GAX14548.1 - 3.7e-12 47.1 11.7 7.5e-12 46.1 11.7 1.5 1 0 0 1 1 1 1 PLAC8 family Ribonuclease_3 PF00636.26 GAX14550.1 - 2.5e-14 53.8 0.0 1.9e-05 25.2 0.0 3.2 2 1 0 2 2 2 2 Ribonuclease III domain PAZ PF02170.22 GAX14550.1 - 2.2e-09 37.3 0.0 5.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 PAZ domain Ribonucleas_3_3 PF14622.6 GAX14550.1 - 2.8e-09 37.2 0.0 0.017 15.3 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Metallophos PF00149.28 GAX14551.1 - 4.2e-31 109.1 0.1 6.3e-31 108.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 GAX14551.1 - 4.1e-07 30.4 0.3 9.8e-07 29.1 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX14551.1 - 0.00012 21.8 0.5 0.033 14.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GAX14551.1 - 0.00022 20.5 0.2 0.04 13.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 GAX14551.1 - 0.0035 17.6 0.0 0.0066 16.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 GAX14551.1 - 0.02 14.7 0.1 0.54 10.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair THB PF18362.1 GAX14551.1 - 0.14 11.8 0.1 25 4.6 0.0 2.7 2 0 0 2 2 2 0 Tri-helix bundle domain zf-C3HC4_3 PF13920.6 GAX14553.1 - 4.1e-08 32.9 10.8 7e-08 32.2 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX14553.1 - 0.0035 17.0 0.4 0.0082 15.9 0.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAX14553.1 - 0.035 14.1 9.8 0.073 13.1 9.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger YopD PF05844.12 GAX14553.1 - 0.037 13.0 0.4 0.06 12.4 0.4 1.2 1 0 0 1 1 1 0 YopD protein DUF4072 PF13284.6 GAX14553.1 - 0.059 13.8 0.6 3 8.3 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) DUF2913 PF11140.8 GAX14553.1 - 0.081 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) PGA2 PF07543.12 GAX14553.1 - 0.12 12.3 0.3 0.34 10.9 0.3 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 WD40 PF00400.32 GAX14554.1 - 6.3e-18 64.8 20.1 0.0038 18.0 0.4 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX14554.1 - 1.1e-06 28.8 4.8 0.14 12.5 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX14554.1 - 0.0015 17.6 0.4 3.2 6.6 0.0 3.4 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Elongin_A PF06881.11 GAX14555.1 - 0.00012 22.6 1.5 0.019 15.5 0.5 2.4 2 0 0 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 GAX14555.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain DEAD PF00270.29 GAX14556.1 - 5.4e-49 166.3 0.0 8.9e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX14556.1 - 1.3e-30 106.0 0.0 5.8e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX14556.1 - 2.1e-07 31.1 0.0 4.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 GAX14559.1 - 4e-31 108.4 0.0 5.8e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14559.1 - 2.2e-11 43.5 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 GAX14559.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 PX domain FTA2 PF13095.6 GAX14559.1 - 0.0054 16.4 0.0 0.042 13.5 0.0 2.0 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Methyltransf_25 PF13649.6 GAX14560.1 - 1.9e-12 47.7 0.0 3.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX14560.1 - 1.8e-10 41.4 0.0 2.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX14560.1 - 5.7e-09 36.0 0.0 7.8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX14560.1 - 1e-08 35.7 0.0 1.6e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX14560.1 - 0.00011 22.0 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX14560.1 - 0.00027 20.3 0.1 0.0006 19.2 0.1 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 GAX14560.1 - 0.015 14.5 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Serine_protease PF18405.1 GAX14560.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Gammaproteobacterial serine protease UPF0146 PF03686.13 GAX14560.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) P_C10 PF14974.6 GAX14561.1 - 0.0024 18.0 0.2 0.0045 17.1 0.0 1.6 2 0 0 2 2 2 1 Protein C10 Thioredoxin_6 PF13848.6 GAX14561.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain EGF_CA PF07645.15 GAX14562.1 - 1.6e-09 37.8 16.1 2.7e-08 33.9 1.8 7.8 6 2 1 7 7 7 2 Calcium-binding EGF domain EGF_3 PF12947.7 GAX14562.1 - 8.8e-09 35.4 25.4 5.4e-05 23.3 1.1 6.5 8 0 0 8 8 8 3 EGF domain hEGF PF12661.7 GAX14562.1 - 0.00013 22.5 11.4 0.00057 20.4 1.8 7.1 7 0 0 7 7 7 3 Human growth factor-like EGF cEGF PF12662.7 GAX14562.1 - 0.00031 20.6 0.4 0.00031 20.6 0.4 6.1 7 0 0 7 7 7 1 Complement Clr-like EGF-like EGF PF00008.27 GAX14562.1 - 0.0017 18.6 2.4 0.0017 18.6 2.4 7.3 6 1 0 6 6 6 2 EGF-like domain TraP PF07296.11 GAX14562.1 - 0.011 15.0 0.2 0.022 14.0 0.2 1.4 1 0 0 1 1 1 0 TraP protein FXa_inhibition PF14670.6 GAX14562.1 - 0.02 15.2 1.4 0.02 15.2 1.4 7.2 7 1 1 8 8 8 0 Coagulation Factor Xa inhibitory site DUF5011 PF16403.5 GAX14562.1 - 0.087 13.0 2.4 1.2 9.3 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5011) Thioredoxin_2 PF13098.6 GAX14563.1 - 0.066 13.7 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain DSBA PF01323.20 GAX14563.1 - 0.078 12.7 0.2 0.46 10.2 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain CUE PF02845.16 GAX14563.1 - 0.091 12.5 0.0 0.45 10.3 0.0 2.2 1 1 0 1 1 1 0 CUE domain CCDC50_N PF15295.6 GAX14563.1 - 0.33 11.1 10.5 0.6 10.3 1.8 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 50 N-terminus PhaP_Bmeg PF09602.10 GAX14563.1 - 0.46 10.4 4.1 1.8 8.5 0.4 2.3 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) His_Phos_2 PF00328.22 GAX14564.1 - 2.8e-14 53.3 0.3 1.1e-13 51.4 0.3 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Transcrip_act PF04949.13 GAX14565.1 - 0.064 13.1 0.9 0.1 12.5 0.9 1.2 1 0 0 1 1 1 0 Transcriptional activator DD_K PF12121.8 GAX14565.1 - 0.58 10.3 6.7 0.32 11.1 0.4 2.4 2 0 0 2 2 2 0 Dermaseptin SOG2 PF10428.9 GAX14565.1 - 0.89 8.7 3.2 1 8.5 3.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein NAD_binding_5 PF07994.12 GAX14566.1 - 4.5e-59 200.4 0.0 6.4e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAX14566.1 - 4.4e-24 84.8 0.0 7.9e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase PfkB PF00294.24 GAX14566.1 - 7.6e-13 48.4 0.1 7.8e-12 45.1 0.1 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HMG_box PF00505.19 GAX14566.1 - 4.5e-05 23.8 2.0 0.00012 22.4 1.5 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX14566.1 - 0.00062 20.3 1.3 0.0013 19.3 1.3 1.5 1 0 0 1 1 1 1 HMG-box domain HLH PF00010.26 GAX14568.1 - 0.00086 19.2 1.1 0.00086 19.2 1.1 1.8 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain eIF3_subunit PF08597.10 GAX14568.1 - 0.073 13.0 1.2 0.11 12.4 1.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BRD4_CDT PF17105.5 GAX14568.1 - 5.3 6.7 7.6 5.5 6.7 2.8 2.4 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 bZIP_1 PF00170.21 GAX14569.1 - 1.7e-09 37.7 12.8 4.7e-09 36.2 12.8 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX14569.1 - 5.1e-06 26.5 16.3 1.4e-05 25.1 16.3 1.7 1 0 0 1 1 1 1 Basic region leucine zipper CENP-Q PF13094.6 GAX14569.1 - 0.0001 22.5 0.3 0.0012 19.1 0.4 2.3 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF3584 PF12128.8 GAX14569.1 - 0.0049 14.5 5.1 0.0082 13.7 5.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.9 GAX14569.1 - 0.066 12.3 4.1 0.16 11.0 4.1 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HemX PF04375.14 GAX14569.1 - 1 8.6 8.6 0.057 12.7 3.2 1.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TFIIA PF03153.13 GAX14569.1 - 1.2 9.0 10.2 1.9 8.4 10.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_Maf PF03131.17 GAX14569.1 - 1.3 9.6 11.2 0.3 11.6 7.0 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Lipase_3 PF01764.25 GAX14570.1 - 1.5e-16 60.5 0.0 3.6e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Pheromone PF08015.11 GAX14570.1 - 0.03 15.3 0.5 0.35 11.9 0.0 2.9 2 1 1 3 3 3 0 Fungal mating-type pheromone Bromodomain PF00439.25 GAX14571.1 - 1.2e-12 47.7 0.1 4.3e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Bromodomain PWWP PF00855.17 GAX14571.1 - 5.8e-06 26.6 0.2 5.8e-06 26.6 0.2 3.0 2 1 0 2 2 2 1 PWWP domain Chloroa_b-bind PF00504.21 GAX14572.1 - 3.1e-40 138.3 0.0 4.2e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ABC2_membrane PF01061.24 GAX14573.1 - 1.2e-34 119.6 20.4 1.2e-34 119.6 20.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAX14573.1 - 3.4e-22 79.4 0.0 5.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX14573.1 - 4.7e-08 32.5 18.0 6.9e-08 32.0 18.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAX14573.1 - 0.00037 20.4 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 GAX14573.1 - 0.0004 20.3 0.0 0.73 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX14573.1 - 0.0021 18.5 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAX14573.1 - 0.008 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 GAX14573.1 - 0.019 14.7 0.0 0.065 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAX14573.1 - 0.038 14.1 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Dynamin family SMC_N PF02463.19 GAX14573.1 - 0.12 11.8 0.0 0.43 10.0 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Nop16 PF09420.10 GAX14574.1 - 1.3e-19 71.1 7.4 2.8e-12 47.1 0.3 2.0 1 1 0 2 2 2 2 Ribosome biogenesis protein Nop16 Dor1 PF04124.12 GAX14575.1 - 5.9e-35 120.5 14.4 9e-34 116.7 13.1 2.4 2 1 0 2 2 2 1 Dor1-like family Sec5 PF15469.6 GAX14575.1 - 1.5e-05 24.9 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Exo84_C PF16528.5 GAX14575.1 - 0.00016 21.6 3.6 0.0061 16.4 1.9 3.0 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Apolipoprotein PF01442.18 GAX14575.1 - 0.0015 18.5 2.9 0.0015 18.5 2.9 4.1 3 2 0 4 4 4 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 GAX14575.1 - 0.18 11.8 2.4 1.7 8.7 0.2 3.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SIR2 PF02146.17 GAX14576.1 - 7.8e-35 120.4 0.1 1.2e-34 119.8 0.1 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAX14576.1 - 2e-06 27.6 0.0 0.061 13.1 0.0 2.8 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain CutC PF03932.14 GAX14576.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 CutC family zf-NADH-PPase PF09297.11 GAX14576.1 - 7.6 6.3 7.5 11 5.8 0.3 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Presenilin PF01080.17 GAX14577.1 - 6.8e-111 370.9 1.1 2.8e-72 243.7 2.6 2.0 2 0 0 2 2 2 2 Presenilin SUIM_assoc PF16619.5 GAX14577.1 - 0.00034 20.6 3.9 0.11 12.6 1.7 2.6 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 CitMHS PF03600.16 GAX14577.1 - 0.0027 17.0 0.0 0.026 13.8 0.0 2.2 1 1 0 1 1 1 1 Citrate transporter UPF0029 PF01205.19 GAX14578.1 - 1.3e-28 99.3 0.0 1.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 EFG_C PF00679.24 GAX14578.1 - 0.00021 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF1949 PF09186.11 GAX14578.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) Pea-VEAacid PF08111.11 GAX14578.1 - 0.16 12.3 4.0 1.4 9.4 0.2 2.8 3 0 0 3 3 3 0 Pea-VEAacid family Chloroa_b-bind PF00504.21 GAX14579.1 - 1e-28 100.9 0.1 1.6e-28 100.2 0.0 1.4 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Ribosomal_S3Ae PF01015.18 GAX14580.1 - 3.4e-81 271.7 0.9 4e-81 271.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family CRAL_TRIO PF00650.20 GAX14581.1 - 4e-16 59.1 0.2 5.6e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX14581.1 - 2.6e-06 27.7 0.1 5.3e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain PrsW-protease PF13367.6 GAX14582.1 - 0.19 11.2 0.9 0.29 10.6 0.1 1.7 2 0 0 2 2 2 0 PrsW family intramembrane metalloprotease TerY_C PF15616.6 GAX14584.1 - 0.19 11.8 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain tRNA-synt_2d PF01409.20 GAX14585.1 - 4.6e-91 304.6 0.0 6.4e-91 304.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_bind PF01588.20 GAX14585.1 - 2.9e-22 78.6 0.0 6.7e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain Phe_tRNA-synt_N PF02912.18 GAX14585.1 - 3.5e-17 62.1 0.4 3.5e-17 62.1 0.4 2.0 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain Mst1_SARAH PF11629.8 GAX14585.1 - 0.075 13.1 0.5 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Phasin PF05597.11 GAX14585.1 - 1.7 8.6 5.5 0.88 9.6 0.1 2.6 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SIR2 PF02146.17 GAX14586.1 - 3.4e-48 163.9 0.0 3.4e-46 157.4 0.0 2.9 1 1 0 1 1 1 1 Sir2 family ZZ PF00569.17 GAX14586.1 - 2.3e-09 36.9 8.9 2.3e-09 36.9 8.9 2.7 3 0 0 3 3 3 1 Zinc finger, ZZ type Skp1_POZ PF03931.15 GAX14587.1 - 1.4e-17 63.6 1.5 3.2e-17 62.4 1.5 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 GAX14587.1 - 4e-16 58.8 0.1 4e-16 58.8 0.1 2.3 2 1 0 2 2 2 1 Skp1 family, dimerisation domain BTB PF00651.31 GAX14587.1 - 5.3e-05 23.4 0.1 0.016 15.4 0.0 2.2 1 1 1 2 2 2 2 BTB/POZ domain IFT46_B_C PF12317.8 GAX14587.1 - 0.018 14.8 0.3 0.023 14.4 0.3 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF3246 PF11596.8 GAX14587.1 - 0.045 13.2 1.3 0.052 13.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SLM4 PF16818.5 GAX14587.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein SLM4 DUF4611 PF15387.6 GAX14587.1 - 0.41 10.9 3.9 0.16 12.2 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AMP-binding PF00501.28 GAX14588.1 - 1.1e-91 307.5 0.1 1.5e-91 307.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAX14588.1 - 3e-07 31.3 0.0 8.2e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TP6A_N PF04406.14 GAX14589.1 - 5.5e-21 74.3 0.1 1.1e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Pkinase PF00069.25 GAX14590.1 - 1.8e-60 204.6 0.1 4.5e-60 203.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 GAX14590.1 - 7.1e-53 176.6 0.1 2.4e-19 69.2 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX14590.1 - 4.9e-28 98.1 0.0 7.9e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX14590.1 - 0.002 18.1 0.4 0.0064 16.4 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX14590.1 - 0.0064 15.8 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAX14590.1 - 0.026 13.3 0.2 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 GAX14590.1 - 0.16 11.3 0.1 0.33 10.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cupin_2 PF07883.11 GAX14590.1 - 0.17 11.6 2.4 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Cupin domain DUF2201_N PF13203.6 GAX14590.1 - 0.37 10.3 1.9 0.6 9.7 1.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain ALMT PF11744.8 GAX14590.1 - 1.8 7.3 3.7 2.4 6.9 3.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Tim17 PF02466.19 GAX14591.1 - 1.4e-30 105.9 6.0 1.8e-30 105.6 6.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HSP70 PF00012.20 GAX14592.1 - 1e-264 879.3 3.9 1.2e-264 879.1 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX14592.1 - 1.7e-16 60.0 0.1 1.5e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 GAX14592.1 - 0.015 14.3 0.1 0.063 12.3 0.1 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain PilM_2 PF11104.8 GAX14592.1 - 0.017 14.2 0.1 2.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.18 GAX14592.1 - 0.062 12.6 0.1 0.13 11.5 0.1 1.6 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase LRR_6 PF13516.6 GAX14593.1 - 5.1e-23 79.1 14.1 0.0068 16.4 0.1 10.8 11 0 0 11 11 11 6 Leucine Rich repeat Response_reg PF00072.24 GAX14593.1 - 9e-18 64.5 0.1 3.2e-17 62.7 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain LRR_1 PF00560.33 GAX14593.1 - 3.8e-06 26.7 7.1 4.6 8.2 0.0 7.1 7 0 0 7 7 7 1 Leucine Rich Repeat PAS_3 PF08447.12 GAX14593.1 - 4.1e-06 27.0 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold LRR_4 PF12799.7 GAX14593.1 - 0.0065 16.9 12.4 0.46 11.0 0.7 5.4 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX14593.1 - 0.096 12.5 9.3 2 8.2 2.9 5.1 4 1 0 4 4 4 0 Leucine rich repeat PAP_fibrillin PF04755.12 GAX14595.1 - 2.7e-08 34.0 0.1 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 2 PAP_fibrillin FA_desaturase_2 PF03405.14 GAX14596.1 - 2.5e-131 437.4 0.0 2.9e-131 437.1 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 GAX14596.1 - 0.006 17.0 0.2 0.5 10.8 0.0 2.7 3 0 0 3 3 3 1 Rubrerythrin Mito_carr PF00153.27 GAX14597.1 - 6.5e-34 115.7 3.8 5.5e-18 64.7 0.1 3.8 2 1 1 3 3 3 3 Mitochondrial carrier protein TTL PF03133.15 GAX14598.1 - 6.9e-19 68.1 0.0 3.1e-18 65.9 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAX14598.1 - 1.3e-07 31.2 0.0 0.00078 18.8 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.11 GAX14598.1 - 0.00015 21.4 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 GAX14598.1 - 0.011 15.0 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 GAX14598.1 - 0.032 13.8 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAX14598.1 - 0.15 11.6 0.1 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Amino_oxidase PF01593.24 GAX14599.1 - 5.1e-38 131.5 0.0 6.3e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAX14599.1 - 4.1e-13 49.6 0.1 4.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX14599.1 - 7.9e-11 42.0 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAX14599.1 - 2.9e-09 36.1 5.1 3.9e-05 22.5 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 GAX14599.1 - 3.5e-09 36.3 1.0 0.00054 19.2 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAX14599.1 - 1.2e-07 31.3 0.4 0.005 16.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX14599.1 - 4e-07 29.7 0.3 9.7e-05 21.9 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX14599.1 - 2.6e-06 27.5 0.4 0.034 14.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAX14599.1 - 2.6e-06 26.9 1.5 0.0002 20.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX14599.1 - 6.3e-05 22.2 2.6 0.065 12.3 0.4 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 GAX14599.1 - 6.7e-05 23.4 0.9 0.2 12.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX14599.1 - 0.00019 20.8 0.1 0.00037 19.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 GAX14599.1 - 0.0037 16.6 0.1 0.0071 15.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAX14599.1 - 0.045 12.8 1.4 0.05 12.7 0.3 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAX14599.1 - 0.078 11.8 1.9 0.22 10.3 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase MCRA PF06100.11 GAX14599.1 - 0.17 10.6 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 MCRA family Shisa PF13908.6 GAX14601.1 - 0.0079 16.5 0.4 0.0079 16.5 0.4 1.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Mucin PF01456.17 GAX14601.1 - 0.1 12.6 1.7 0.17 11.9 1.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Mito_carr PF00153.27 GAX14602.1 - 5.4e-19 67.9 5.1 3.7e-07 30.0 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Aconitase PF00330.20 GAX14603.1 - 1.9e-157 525.0 0.1 2.2e-157 524.8 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAX14603.1 - 1.7e-35 122.2 0.0 3.2e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 GAX14603.1 - 0.027 14.1 0.0 0.39 10.3 0.0 2.4 1 1 0 1 1 1 0 Aconitate hydratase 2 N-terminus RF-1 PF00472.20 GAX14604.1 - 3.2e-24 85.1 2.6 3.2e-24 85.1 2.6 1.8 2 0 0 2 2 2 1 RF-1 domain MJ1316 PF04457.12 GAX14604.1 - 7.4e-16 58.7 0.1 1.7e-15 57.5 0.1 1.6 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Acyl-CoA_dh_1 PF00441.24 GAX14605.1 - 3e-35 121.6 1.5 4.8e-35 121.0 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAX14605.1 - 4.4e-15 55.7 0.0 6.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAX14605.1 - 5.6e-14 52.6 1.2 9.9e-14 51.8 1.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX14605.1 - 7.7e-14 52.3 0.0 1.8e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain TrbC PF04956.13 GAX14605.1 - 0.19 11.9 0.0 0.44 10.8 0.0 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family 60KD_IMP PF02096.20 GAX14606.1 - 4.1e-15 56.1 0.0 4.7e-14 52.6 0.0 2.2 1 1 0 1 1 1 1 60Kd inner membrane protein DNA_pol_viral_C PF00336.18 GAX14606.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain La PF05383.17 GAX14607.1 - 8.1e-14 51.4 0.0 2.1e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 La domain MFS_1 PF07690.16 GAX14608.1 - 6.2e-10 38.5 42.3 6.2e-10 38.5 42.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Gcn1_N PF12074.8 GAX14609.1 - 0.11 11.8 0.1 0.55 9.5 0.1 1.9 2 1 1 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Mpv17_PMP22 PF04117.12 GAX14610.1 - 9.4e-18 64.2 1.3 1.8e-17 63.3 1.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family YrzO PF14142.6 GAX14610.1 - 0.16 11.8 0.3 0.36 10.7 0.3 1.6 1 0 0 1 1 1 0 YrzO-like protein DUF4936 PF16290.5 GAX14611.1 - 0.028 15.1 0.0 0.054 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) Histidinol_dh PF00815.20 GAX14612.1 - 3.5e-128 428.1 0.4 4.3e-128 427.8 0.4 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Metal_resist PF13801.6 GAX14612.1 - 0.093 12.9 0.7 1.5 9.1 0.2 2.4 2 0 0 2 2 2 0 Heavy-metal resistance SIP PF04954.13 GAX14612.1 - 0.1 13.1 1.4 0.95 10.0 0.3 2.5 2 0 0 2 2 2 0 Siderophore-interacting protein GSHPx PF00255.19 GAX14613.1 - 2e-05 24.1 0.0 0.00085 18.9 0.0 2.1 1 1 1 2 2 2 2 Glutathione peroxidase EF-hand_7 PF13499.6 GAX14614.1 - 1.3e-09 38.3 0.8 2.7e-09 37.4 0.8 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX14614.1 - 1.7e-09 36.6 3.2 0.00012 21.4 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GAX14614.1 - 7e-06 25.6 7.2 0.014 15.3 0.1 2.9 3 0 0 3 3 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX14614.1 - 0.00012 21.4 0.5 0.084 12.4 0.3 2.6 2 0 0 2 2 2 2 EF hand Neurensin PF14927.6 GAX14614.1 - 0.018 14.7 0.5 0.018 14.7 0.5 1.8 2 0 0 2 2 2 0 Neurensin SPARC_Ca_bdg PF10591.9 GAX14614.1 - 0.057 13.7 1.1 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3285 PF11688.8 GAX14614.1 - 0.057 13.3 2.0 0.15 12.0 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Phage_holin_3_6 PF07332.11 GAX14614.1 - 0.074 13.1 9.7 0.45 10.6 0.8 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PRA1 PF03208.19 GAX14614.1 - 0.68 9.6 4.6 1.1 8.9 4.6 1.2 1 0 0 1 1 1 0 PRA1 family protein EF-hand_8 PF13833.6 GAX14614.1 - 0.97 9.3 3.2 2.7 7.9 1.7 2.3 1 1 1 2 2 2 0 EF-hand domain pair Chordopox_A13L PF05961.11 GAX14614.1 - 1.2 9.4 4.1 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus A13L protein F_actin_cap_B PF01115.17 GAX14615.1 - 8.7e-38 130.3 0.0 1e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF4503 PF14951.6 GAX14615.1 - 0.00054 18.5 0.1 0.00074 18.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) SnoaL PF07366.12 GAX14616.1 - 0.016 15.0 0.0 0.078 12.8 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Fer2_BFD PF04324.15 GAX14616.1 - 0.083 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Pex19 PF04614.12 GAX14618.1 - 8e-33 114.2 20.7 8e-33 114.2 20.7 2.0 2 0 0 2 2 2 1 Pex19 protein family Corazonin PF17308.2 GAX14618.1 - 0.82 10.0 11.8 0.046 14.1 3.0 2.6 1 1 0 2 2 2 0 Pro-corazonin GSK-3_bind PF05350.12 GAX14618.1 - 0.85 8.9 7.8 0.23 10.8 1.5 2.3 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding GET2 PF08690.10 GAX14618.1 - 5 6.7 39.7 0.18 11.4 21.9 2.5 1 1 1 2 2 2 0 GET complex subunit GET2 Imm5 PF14423.6 GAX14618.1 - 8.8 6.5 7.0 2.2 8.5 0.4 2.6 3 0 0 3 3 3 0 Immunity protein Imm5 Kelch_1 PF01344.25 GAX14619.1 - 7.5e-26 89.5 0.3 2.9e-09 36.3 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 GAX14619.1 - 3.3e-23 81.4 5.2 3.6e-08 33.3 0.1 5.8 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 GAX14619.1 - 4.1e-22 78.0 8.7 0.00066 19.9 0.0 7.2 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX14619.1 - 2.6e-21 75.1 0.7 7.4e-07 29.2 0.0 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_5 PF13854.6 GAX14619.1 - 1.3e-16 60.2 2.2 0.0001 22.2 0.0 5.1 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 GAX14619.1 - 5.2e-10 38.9 7.6 0.0072 16.3 0.1 5.3 5 1 0 5 5 5 4 Kelch motif Aminotran_3 PF00202.21 GAX14620.1 - 1e-74 251.7 0.0 1.3e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAX14620.1 - 0.00033 20.1 0.0 0.00061 19.2 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase LTD PF00932.19 GAX14621.1 - 6.8e-15 55.4 0.6 1.2e-14 54.6 0.6 1.4 1 0 0 1 1 1 1 Lamin Tail Domain Arf PF00025.21 GAX14622.1 - 3.8e-74 247.9 0.0 4.3e-74 247.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAX14622.1 - 1.7e-14 54.0 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAX14622.1 - 3.6e-12 46.1 0.1 3.6e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAX14622.1 - 1.4e-11 44.2 0.0 1.6e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAX14622.1 - 2.8e-10 39.9 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX14622.1 - 9e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX14622.1 - 8.2e-07 28.6 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAX14622.1 - 0.00045 19.8 0.2 0.0028 17.2 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 GAX14622.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 GAX14622.1 - 0.15 12.6 0.0 0.21 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain Morc6_S5 PF17942.1 GAX14622.1 - 0.17 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like Ribosomal_L7Ae PF01248.26 GAX14624.1 - 2.1e-12 46.6 0.1 4.2e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.22 GAX14624.1 - 1.4e-05 24.9 0.0 0.15 11.9 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GLE1 PF07817.13 GAX14625.1 - 2.6e-26 92.4 0.0 4.3e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein zf-CCCH_4 PF18044.1 GAX14625.1 - 1.7e-11 43.6 4.8 3e-11 42.8 4.8 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAX14625.1 - 9.2e-08 31.9 8.2 1.6e-07 31.1 8.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAX14625.1 - 6.8e-07 29.0 4.7 1.2e-06 28.3 4.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAX14625.1 - 0.00033 21.3 0.7 0.00033 21.3 0.7 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 GAX14625.1 - 0.0018 18.6 5.2 0.0034 17.8 5.2 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger MutS_III PF05192.18 GAX14625.1 - 0.12 12.6 3.8 0.19 11.9 3.8 1.4 1 0 0 1 1 1 0 MutS domain III His_Phos_1 PF00300.22 GAX14626.1 - 9.2e-36 123.4 0.0 8.7e-32 110.4 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 GAX14626.1 - 0.11 11.9 0.0 0.24 10.7 0.1 1.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) AD PF09793.9 GAX14627.1 - 7.8e-20 70.8 0.2 1.3e-19 70.1 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 GAX14627.1 - 1.8e-06 27.6 0.7 8.4e-05 22.2 0.7 2.2 1 1 0 1 1 1 1 Gemin6 protein NUMOD1 PF07453.13 GAX14628.1 - 9.9e-06 25.7 0.0 0.0067 16.7 0.0 2.8 2 0 0 2 2 2 2 NUMOD1 domain PDZ PF00595.24 GAX14628.1 - 6.4e-05 23.2 0.2 0.048 14.0 0.0 3.8 2 1 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX14628.1 - 0.0005 19.9 0.5 0.063 13.1 0.1 3.6 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX14628.1 - 0.0059 16.9 0.0 0.58 10.5 0.0 3.3 2 1 0 2 2 2 1 PDZ domain tRNA_U5-meth_tr PF05958.11 GAX14629.1 - 1.2e-09 37.7 0.0 4.6e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAX14629.1 - 3.8e-07 30.0 0.1 7.3e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX14629.1 - 3.8e-07 30.7 0.2 1.4e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX14629.1 - 1.1e-06 28.3 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAX14629.1 - 5.2e-05 23.9 0.0 0.00015 22.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX14629.1 - 0.0003 20.3 0.1 0.0003 20.3 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAX14629.1 - 0.00077 20.1 0.1 0.0025 18.4 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX14629.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX14629.1 - 0.0054 16.7 0.6 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 GAX14629.1 - 0.0066 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 GAX14629.1 - 0.007 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF2857 PF11198.8 GAX14629.1 - 0.024 14.4 0.2 0.061 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Cyclin_N PF00134.23 GAX14630.1 - 2.4e-15 56.4 0.0 3.8e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX14630.1 - 4.4e-05 23.5 0.3 9.1e-05 22.5 0.3 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain PEMT PF04191.13 GAX14631.1 - 0.0005 20.4 1.4 0.0005 20.4 1.4 2.9 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF962 PF06127.11 GAX14631.1 - 0.85 9.7 7.9 0.11 12.6 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Cyclin_N PF00134.23 GAX14632.1 - 5.1e-17 61.8 1.5 5.3e-17 61.7 0.6 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX14632.1 - 0.002 18.2 0.7 0.0059 16.7 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain FliMN_C PF01052.20 GAX14632.1 - 0.089 12.8 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term Exo_endo_phos PF03372.23 GAX14633.1 - 2.4e-15 56.7 0.1 2.7e-14 53.3 0.1 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAX14633.1 - 0.0035 17.2 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase LSM PF01423.22 GAX14634.1 - 1.2e-19 69.8 0.0 1.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Metallopep PF12044.8 GAX14635.1 - 0.0031 16.2 0.0 0.0031 16.2 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase family Reprolysin_5 PF13688.6 GAX14635.1 - 0.0074 16.5 0.2 0.028 14.6 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX14635.1 - 0.01 16.3 0.9 0.037 14.5 0.0 2.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX14635.1 - 0.039 13.8 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Matrixin DUF2207 PF09972.9 GAX14635.1 - 0.041 12.6 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3152 PF11350.8 GAX14635.1 - 0.053 13.2 0.2 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Reprolysin_4 PF13583.6 GAX14635.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 GAX14635.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A EMP24_GP25L PF01105.24 GAX14635.1 - 3.5 7.5 7.4 1 9.3 0.1 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Metallophos PF00149.28 GAX14636.1 - 3.2e-14 53.9 1.0 2.2e-13 51.2 1.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4329 PF14220.6 GAX14636.1 - 0.026 14.5 0.1 0.88 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) CN_hydrolase PF00795.22 GAX14637.1 - 1.7e-45 155.4 0.0 2.3e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MOZ_SAS PF01853.18 GAX14638.1 - 5.7e-80 267.2 0.8 8.1e-80 266.7 0.8 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAX14638.1 - 5.4e-21 73.9 5.1 5.4e-21 73.9 5.1 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 GAX14638.1 - 2.9e-12 46.3 1.8 6.5e-12 45.2 1.8 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pkinase PF00069.25 GAX14639.1 - 0.00022 20.7 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPT PF03151.16 GAX14640.1 - 2.1e-15 56.8 11.1 3.3e-15 56.2 11.1 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAX14640.1 - 0.003 16.8 2.2 0.003 16.8 2.2 2.5 2 2 0 2 2 2 1 UAA transporter family EamA PF00892.20 GAX14640.1 - 0.0033 17.6 25.2 0.017 15.3 9.3 3.0 2 1 0 2 2 2 2 EamA-like transporter family Lipase_GDSL_2 PF13472.6 GAX14641.1 - 2.6e-08 34.5 0.5 4.8e-08 33.6 0.5 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX14641.1 - 9.7e-08 32.2 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAX14642.1 - 2e-09 38.1 0.3 2.8e-09 37.6 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX14642.1 - 2.4e-07 31.0 0.0 6.1e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lactamase_B_6 PF16661.5 GAX14644.1 - 6.2e-26 91.0 0.0 1.3e-25 90.0 0.0 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 GAX14644.1 - 5.7e-13 49.1 0.0 1.6e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Beta_lactamase3 PF17030.5 GAX14644.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family RabGAP-TBC PF00566.18 GAX14645.1 - 0.0027 17.4 0.3 0.0097 15.6 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Herpes_UL49_5 PF05702.11 GAX14645.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Galactosyl_T PF01762.21 GAX14646.1 - 5.9e-08 32.8 0.1 9.1e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase PS_pyruv_trans PF04230.13 GAX14647.1 - 2.5e-16 60.4 0.0 6.8e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase Galactosyl_T PF01762.21 GAX14648.1 - 4.6e-06 26.6 0.0 7.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase DUF4473 PF14747.6 GAX14648.1 - 0.0078 16.7 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Aa_trans PF01490.18 GAX14649.1 - 9.8e-40 136.5 30.7 3.1e-39 134.8 30.7 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PhoR PF11808.8 GAX14649.1 - 0.24 11.8 0.1 0.24 11.8 0.1 4.3 5 0 0 5 5 5 0 Phosphate regulon sensor protein PhoR zf-RING_2 PF13639.6 GAX14651.1 - 2.2e-10 40.7 13.7 5e-10 39.6 13.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX14651.1 - 9.8e-06 25.8 15.0 9.8e-06 25.8 15.0 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX14651.1 - 1.5e-05 24.7 12.8 3.9e-05 23.4 12.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX14651.1 - 2.6e-05 23.9 7.9 7.9e-05 22.3 7.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX14651.1 - 0.00059 19.7 12.0 0.0011 18.7 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX14651.1 - 0.00091 19.2 9.0 0.00095 19.2 8.1 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GAX14651.1 - 0.0013 18.5 7.4 0.003 17.4 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX14651.1 - 0.0037 17.3 4.8 0.0037 17.3 4.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX14651.1 - 0.014 15.3 10.0 0.014 15.3 10.0 2.2 2 1 0 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 GAX14651.1 - 0.48 10.6 12.5 3.2 8.0 12.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX14651.1 - 0.98 9.1 11.7 0.74 9.5 9.4 2.0 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF4647 PF15504.6 GAX14652.1 - 0.094 11.8 1.2 0.14 11.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) MRP-L46 PF11788.8 GAX14652.1 - 0.81 10.4 5.3 0.16 12.7 0.9 2.1 3 0 0 3 3 3 0 39S mitochondrial ribosomal protein L46 Ig_mannosidase PF17753.1 GAX14653.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Ig-fold domain DUF4856 PF16148.5 GAX14654.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4856) DUF5305 PF17231.2 GAX14654.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Pox_A14 PF05767.12 GAX14654.1 - 0.028 14.6 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Phage_tail_U PF06141.11 GAX14654.1 - 0.087 13.2 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage minor tail protein U CrgA PF06781.12 GAX14654.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA OAD_gamma PF04277.13 GAX14654.1 - 3.1 8.5 6.5 0.6 10.7 1.4 2.2 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Globin PF00042.22 GAX14656.1 - 9.9e-11 42.2 0.0 1.5e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Globin WLM PF08325.10 GAX14657.1 - 2.4e-23 83.2 0.0 5.1e-23 82.2 0.0 1.5 1 1 0 1 1 1 1 WLM domain BSP PF04450.12 GAX14657.1 - 0.0016 18.3 0.2 0.0024 17.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria zf-RanBP PF00641.18 GAX14657.1 - 0.007 15.7 0.9 0.015 14.6 0.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 GAX14657.1 - 0.52 10.3 3.4 0.8 9.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 HSP70 PF00012.20 GAX14658.1 - 3.7e-268 890.7 12.3 4.3e-268 890.5 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX14658.1 - 2.3e-16 59.5 1.5 9.1e-14 51.0 0.3 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GAX14658.1 - 0.00013 21.7 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAX14658.1 - 0.0045 17.4 7.1 5.3 7.5 0.0 4.0 3 3 0 3 3 3 2 Cell division protein FtsA GFRP PF06399.13 GAX14658.1 - 0.12 12.3 0.0 0.62 10.0 0.0 2.1 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF3919 PF13057.6 GAX14658.1 - 0.17 11.5 4.7 0.35 10.4 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DASH_Spc19 PF08287.11 GAX14658.1 - 1.9 8.4 8.3 5.4 6.9 8.3 1.8 1 0 0 1 1 1 0 Spc19 BSP_II PF05432.11 GAX14659.1 - 0.065 12.9 16.4 0.1 12.2 16.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Neur_chan_memb PF02932.16 GAX14659.1 - 0.65 10.0 4.3 0.98 9.4 4.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GET2 PF08690.10 GAX14659.1 - 0.87 9.2 17.0 1.6 8.4 17.0 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 LZ_Tnp_IS66 PF13007.7 GAX14659.1 - 1.3 9.8 12.1 0.11 13.3 6.6 2.2 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Presenilin PF01080.17 GAX14659.1 - 1.7 7.4 8.5 3.1 6.5 8.5 1.5 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GAX14659.1 - 1.8 6.7 12.1 2.7 6.2 12.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 GAX14659.1 - 2.7 8.3 19.3 4 7.7 19.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 GAX14659.1 - 3.5 6.3 8.7 5.2 5.8 8.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 GAX14659.1 - 5.2 6.8 17.6 8.1 6.2 17.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein CAML PF14963.6 GAX14659.1 - 6.7 6.8 14.4 18 5.4 14.4 1.7 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Sec62 PF03839.16 GAX14659.1 - 9.3 5.7 11.2 15 5.0 11.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MCM PF00493.23 GAX14660.1 - 9e-95 316.0 0.0 7.7e-84 280.3 0.0 2.8 3 0 0 3 3 3 2 MCM P-loop domain MCM_OB PF17207.3 GAX14660.1 - 4.8e-34 116.9 0.2 9.3e-34 116.0 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX14660.1 - 6.6e-27 93.8 2.0 1.7e-26 92.4 2.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAX14660.1 - 8.2e-09 36.0 0.7 3.5e-08 34.0 0.1 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAX14660.1 - 5e-07 29.3 0.0 0.00018 21.0 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX14660.1 - 3e-06 27.3 0.0 9.8e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAX14660.1 - 1e-05 25.4 0.0 0.00021 21.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAX14660.1 - 0.13 12.0 0.0 8.9 6.0 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain DEAD PF00270.29 GAX14660.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 GAX14660.1 - 2.1 8.7 5.2 6.6 7.1 0.1 3.8 3 3 1 4 4 4 0 AAA ATPase domain DUF1541 PF07563.11 GAX14661.1 - 0.044 13.7 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Phosphoesterase PF04185.14 GAX14661.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoesterase family Acetyltransf_10 PF13673.7 GAX14662.1 - 0.0025 17.8 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_42C PF08533.10 GAX14662.1 - 0.11 12.2 0.0 4.2 7.2 0.0 2.7 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Acetyltransf_1 PF00583.25 GAX14662.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX14662.1 - 0.14 12.6 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glu_synthase PF01645.17 GAX14665.1 - 3.8e-149 496.8 0.4 2.7e-147 490.7 0.2 2.3 2 0 0 2 2 2 2 Conserved region in glutamate synthase GATase_2 PF00310.21 GAX14665.1 - 1.3e-146 488.6 0.0 1.2e-145 485.5 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 GAX14665.1 - 1.5e-105 352.7 0.1 4.9e-105 351.0 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GAX14665.1 - 1.9e-73 246.1 9.3 3.3e-73 245.3 9.3 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 GAX14665.1 - 0.002 17.2 3.2 0.0048 16.0 3.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PBECR4 PF18813.1 GAX14665.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 DUF2371 PF10177.9 GAX14666.1 - 0.16 12.2 0.9 0.43 10.8 0.9 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Pro_isomerase PF00160.21 GAX14667.1 - 5.2e-47 160.0 0.0 6.1e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA_assoc_C PF09821.9 GAX14669.1 - 0.79 10.3 4.8 0.87 10.1 0.0 2.8 3 0 0 3 3 3 0 C-terminal AAA-associated domain Sas10 PF09368.10 GAX14670.1 - 8.6e-25 87.0 8.6 8.6e-25 87.0 8.6 2.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 GAX14670.1 - 0.24 12.0 0.1 0.24 12.0 0.1 2.4 3 0 0 3 3 3 0 Sas10/Utp3/C1D family Vac14_Fab1_bd PF12755.7 GAX14672.1 - 3.3e-33 114.2 1.5 1.3e-31 109.0 0.4 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 GAX14672.1 - 2.2e-32 112.2 0.8 5.2e-32 110.9 0.8 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.22 GAX14672.1 - 2e-05 24.4 0.7 0.91 10.0 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 GAX14672.1 - 0.055 13.5 0.5 7.4 6.6 0.0 3.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Filament PF00038.21 GAX14673.1 - 0.00087 19.0 122.8 0.012 15.2 17.3 7.6 1 1 2 5 5 5 4 Intermediate filament protein TPR_MLP1_2 PF07926.12 GAX14673.1 - 0.0012 18.9 9.7 0.0012 18.9 9.7 9.6 1 1 7 9 9 9 5 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 GAX14673.1 - 0.0015 18.1 35.4 0.0015 18.1 35.4 6.6 1 1 3 6 6 6 3 Mechanosensitive ion channel porin domain AAA_13 PF13166.6 GAX14673.1 - 0.0025 16.6 24.5 0.0025 16.6 24.5 4.7 1 1 3 5 5 5 2 AAA domain HMMR_N PF15905.5 GAX14673.1 - 0.0045 16.5 23.5 0.0045 16.5 23.5 7.6 1 1 6 7 7 7 3 Hyaluronan mediated motility receptor N-terminal ASPRs PF17641.2 GAX14673.1 - 0.0071 16.6 3.4 0.0071 16.6 3.4 4.1 4 1 1 5 5 5 1 Ancylostoma-associated secreted protein related BRX_N PF13713.6 GAX14673.1 - 0.14 11.9 0.1 0.14 11.9 0.1 3.8 4 1 1 5 5 5 0 Transcription factor BRX N-terminal domain Lebercilin PF15619.6 GAX14673.1 - 0.14 11.8 136.8 0.066 12.9 12.1 8.5 2 2 5 8 8 8 0 Ciliary protein causing Leber congenital amaurosis disease DASH_Hsk3 PF08227.11 GAX14673.1 - 0.6 10.5 0.0 0.34 11.3 1.0 9.3 11 1 1 12 12 12 0 DASH complex subunit Hsk3 like GST_N_3 PF13417.6 GAX14674.1 - 9.9e-13 48.3 0.0 2.4e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX14674.1 - 4.1e-12 46.3 0.0 8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX14674.1 - 1.1e-08 35.3 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX14674.1 - 0.00013 21.9 0.0 0.00024 21.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAX14674.1 - 0.00031 20.9 0.1 0.0024 18.0 0.0 2.4 3 0 0 3 3 3 1 Glutaredoxin GST_C PF00043.25 GAX14674.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAX14674.1 - 0.028 15.1 0.0 0.062 14.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Not3 PF04065.15 GAX14675.1 - 3.3e-78 262.3 20.7 3.3e-78 262.3 20.7 2.6 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 GAX14675.1 - 8.3e-45 152.1 7.9 8.3e-45 152.1 7.9 2.7 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family FOXO-TAD PF16676.5 GAX14675.1 - 0.67 10.4 4.4 1.4 9.3 4.4 1.6 1 0 0 1 1 1 0 Transactivation domain of FOXO protein family Hamartin PF04388.12 GAX14675.1 - 1.5 7.4 25.7 0.021 13.5 16.5 2.0 2 0 0 2 2 2 0 Hamartin protein V_ATPase_I PF01496.19 GAX14675.1 - 9.3 4.0 20.6 0.014 13.3 5.1 2.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PP2C PF00481.21 GAX14676.1 - 4.9e-64 216.4 0.1 2.9e-63 213.9 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX14676.1 - 0.00011 21.9 0.4 0.00031 20.4 0.4 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF5084 PF16894.5 GAX14677.1 - 0.011 16.1 1.9 0.016 15.6 0.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5084) Trp_Tyr_perm PF03222.13 GAX14677.1 - 0.013 14.6 1.2 0.013 14.6 1.2 1.6 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family Pribosyltran_N PF13793.6 GAX14678.1 - 0.044 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Ribosomal_S21 PF01165.20 GAX14679.1 - 2.4e-17 62.4 6.9 2.4e-17 62.4 6.9 1.8 1 1 1 2 2 2 1 Ribosomal protein S21 PEHE PF15275.6 GAX14679.1 - 2 9.1 6.7 2.6 8.7 6.7 1.2 1 0 0 1 1 1 0 PEHE domain Helicase_C PF00271.31 GAX14680.1 - 2.6e-15 56.7 0.0 2.4e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX14680.1 - 4.6e-14 52.6 0.0 1.2e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 GAX14680.1 - 1.7e-11 44.7 3.7 1.7e-11 44.7 3.7 2.7 4 0 0 4 4 4 1 RecQ zinc-binding ResIII PF04851.15 GAX14680.1 - 0.018 15.1 0.0 0.087 12.8 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Spt4 PF06093.13 GAX14680.1 - 6.6 6.9 7.2 3.6 7.7 0.7 3.4 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger tRNA-synt_1 PF00133.22 GAX14681.1 - 1.1e-201 671.3 0.0 1.4e-200 667.6 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAX14681.1 - 3.9e-39 134.0 0.1 8.1e-39 133.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAX14681.1 - 2.7e-15 56.0 0.1 2.3e-06 26.7 0.0 4.1 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAX14681.1 - 7.2e-12 45.2 0.0 7.5e-08 32.1 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 GAX14681.1 - 1.7e-05 25.0 4.9 6.9e-05 23.1 4.9 2.2 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 GAX14681.1 - 8.1e-05 22.1 0.4 0.12 11.7 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 GAX14681.1 - 5.1 6.3 5.7 3.4 6.9 0.0 3.1 4 0 0 4 4 4 0 tRNA synthetases class I (W and Y) K_channel_TID PF07941.11 GAX14682.1 - 6.7 7.2 9.3 6.6 7.3 1.8 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Zw10 PF06248.13 GAX14683.1 - 3.6e-26 91.8 8.3 7.2e-24 84.3 7.2 3.5 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 DUF1943 PF09172.11 GAX14683.1 - 0.11 11.7 0.2 0.19 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Nop14 PF04147.12 GAX14684.1 - 2.2 6.4 17.9 2.6 6.1 17.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAX14684.1 - 7.5 5.8 18.0 9 5.5 18.0 1.1 1 0 0 1 1 1 0 BUD22 YccV-like PF08755.11 GAX14686.1 - 0.031 14.8 0.1 0.077 13.5 0.0 1.8 2 0 0 2 2 2 0 Hemimethylated DNA-binding protein YccV like COX15-CtaA PF02628.15 GAX14686.1 - 0.14 11.2 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein 2OG-FeII_Oxy_3 PF13640.6 GAX14687.1 - 1.3e-13 51.6 0.0 2.3e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BAG PF02179.16 GAX14687.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 BAG domain Siva PF05458.12 GAX14688.1 - 9.4e-06 25.4 16.3 2.6e-05 24.0 16.3 1.6 1 1 0 1 1 1 1 Cd27 binding protein (Siva) OpcA_G6PD_assem PF10128.9 GAX14688.1 - 0.063 12.8 0.3 0.086 12.3 0.3 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit BPL_LplA_LipB PF03099.19 GAX14689.1 - 1.7e-10 40.9 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PKcGMP_CC PF16808.5 GAX14690.1 - 0.034 14.0 2.5 0.095 12.6 2.2 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Glutaredoxin2_C PF04399.13 GAX14690.1 - 0.16 11.8 2.4 0.34 10.8 2.4 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain FapA PF03961.13 GAX14690.1 - 0.55 8.8 6.3 1 7.9 6.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A CRR7 PF12095.8 GAX14690.1 - 0.69 10.4 9.7 0.096 13.1 3.3 2.5 1 1 1 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF572 PF04502.13 GAX14690.1 - 2.3 7.8 17.6 3.1 7.3 17.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nucleos_tra2_N PF01773.20 GAX14691.1 - 0.081 13.5 0.0 0.23 12.1 0.0 1.7 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus DUF5546 PF17700.1 GAX14691.1 - 0.39 11.1 5.8 1 9.7 5.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5546) Thr_synth_N PF14821.6 GAX14692.1 - 6.4e-24 84.0 0.0 1.8e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 GAX14692.1 - 1.5e-12 47.6 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Flavi_DEAD PF07652.14 GAX14692.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Flavivirus DEAD domain Ntox44 PF15607.6 GAX14692.1 - 0.15 12.3 0.0 0.49 10.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial toxin 44 Sigma_reg_N PF13800.6 GAX14693.1 - 0.082 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Membralin PF09746.9 GAX14694.1 - 5.9e-08 32.2 0.4 5.9e-08 32.2 0.4 1.7 2 0 0 2 2 2 1 Tumour-associated protein ADH_zinc_N_2 PF13602.6 GAX14695.1 - 9e-08 33.2 0.0 3e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX14695.1 - 0.0004 20.2 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 GAX14695.1 - 0.0083 15.6 0.0 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 GAX14695.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 GAX14696.1 - 7.4e-50 169.7 0.0 1.3e-49 169.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14696.1 - 1.9e-26 92.9 0.0 3.2e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 GAX14696.1 - 1.4e-06 28.3 0.3 2.6e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Kdo PF06293.14 GAX14696.1 - 0.00019 20.9 0.4 0.00038 19.9 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I_2 PF17014.5 GAX14696.1 - 0.00066 19.8 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein APH PF01636.23 GAX14696.1 - 0.0028 17.6 0.1 0.0028 17.6 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX14696.1 - 0.0051 16.4 0.1 0.018 14.6 0.1 1.9 1 1 0 1 1 1 1 RIO1 family TPR_14 PF13428.6 GAX14696.1 - 0.083 13.8 4.1 1.3 10.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX14696.1 - 0.2 12.2 5.5 2.3 8.8 0.6 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat HECT PF00632.25 GAX14697.1 - 1.1e-15 57.9 0.0 2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 GAX14697.1 - 1.9e-05 24.8 0.0 5.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 SPRY domain C1_2 PF03107.16 GAX14697.1 - 0.27 11.6 17.3 0.14 12.5 4.9 2.9 2 0 0 2 2 2 0 C1 domain zf-RanBP PF00641.18 GAX14697.1 - 1.5 8.2 14.8 0.16 11.3 9.8 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Mpv17_PMP22 PF04117.12 GAX14698.1 - 1.7e-14 53.8 1.1 3.1e-14 52.9 1.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family RRN3 PF05327.11 GAX14699.1 - 1.7 7.1 7.1 4.5 5.7 7.1 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 2OG-FeII_Oxy PF03171.20 GAX14700.1 - 0.0005 20.5 0.0 0.0015 19.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAX14700.1 - 0.066 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal CRAL_TRIO PF00650.20 GAX14701.1 - 4.2e-11 42.8 0.0 6.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain JAB PF01398.21 GAX14702.1 - 3e-33 114.3 0.1 6.4e-33 113.2 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAX14702.1 - 3.8e-14 53.1 0.7 6.8e-14 52.2 0.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 GAX14702.1 - 2.7e-06 27.2 0.0 4.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 GAX14702.1 - 0.0048 17.0 0.3 0.0086 16.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) APH PF01636.23 GAX14703.1 - 4.4e-13 49.7 0.9 6.2e-13 49.2 0.9 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAX14703.1 - 7.3e-13 48.5 0.0 1.6e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 GAX14703.1 - 1.1e-06 27.8 0.1 1.7e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 GAX14703.1 - 2.9e-06 26.9 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 GAX14703.1 - 0.00025 20.7 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 GAX14703.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase HSF_DNA-bind PF00447.17 GAX14704.1 - 7.4e-42 141.9 1.0 4.5e-20 72.1 0.0 2.3 2 0 0 2 2 2 2 HSF-type DNA-binding Lin0512_fam PF09585.10 GAX14704.1 - 3.1e-07 30.4 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) HAP1_N PF04849.13 GAX14706.1 - 0.00017 20.9 4.5 0.00019 20.7 4.5 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.8 GAX14706.1 - 0.0016 18.4 11.0 0.059 13.4 2.2 2.2 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding KIAA1430 PF13879.6 GAX14706.1 - 0.0019 18.9 2.4 0.0024 18.6 2.4 1.3 1 0 0 1 1 1 1 KIAA1430 homologue KASH_CCD PF14662.6 GAX14706.1 - 0.0021 17.9 6.4 0.0034 17.2 6.4 1.4 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH rRNA_processing PF08524.11 GAX14706.1 - 0.0035 17.4 3.5 0.0038 17.3 3.5 1.0 1 0 0 1 1 1 1 rRNA processing SKA2 PF16740.5 GAX14706.1 - 0.0038 17.0 5.3 0.005 16.6 5.3 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 bZIP_2 PF07716.15 GAX14706.1 - 0.0091 16.1 4.2 0.0091 16.1 4.2 2.0 1 1 1 2 2 2 1 Basic region leucine zipper TSC22 PF01166.18 GAX14706.1 - 0.023 15.0 5.1 0.045 14.0 5.1 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family GIT_CC PF16559.5 GAX14706.1 - 0.026 14.4 10.4 0.1 12.5 6.1 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 GAX14706.1 - 0.029 14.5 7.3 0.057 13.5 4.8 2.0 1 1 1 2 2 2 0 bZIP transcription factor Fmp27_WPPW PF10359.9 GAX14706.1 - 0.052 12.4 4.3 0.053 12.4 4.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 GAX14706.1 - 0.095 12.0 3.4 0.1 12.0 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 GAX14706.1 - 0.098 13.1 10.1 0.19 12.2 10.1 1.5 1 1 0 1 1 1 0 Cell division protein ZapB WDCP PF15390.6 GAX14706.1 - 0.17 10.3 2.7 0.17 10.2 2.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF948 PF06103.11 GAX14706.1 - 0.2 11.9 1.4 0.37 11.1 1.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Apt1 PF10351.9 GAX14706.1 - 0.3 9.9 6.0 0.36 9.6 6.0 1.2 1 1 0 1 1 1 0 Golgi-body localisation protein domain YabA PF06156.13 GAX14706.1 - 0.33 11.6 6.2 0.47 11.1 6.2 1.5 1 1 0 1 1 1 0 Initiation control protein YabA OmpH PF03938.14 GAX14706.1 - 0.39 11.1 10.4 0.44 10.9 10.4 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HIP1_clath_bdg PF16515.5 GAX14706.1 - 0.42 11.3 11.9 0.22 12.1 10.1 1.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 60KD_IMP PF02096.20 GAX14706.1 - 0.76 9.7 2.2 0.56 10.1 1.2 1.3 1 1 0 1 1 1 0 60Kd inner membrane protein LPP PF04728.13 GAX14706.1 - 1.5 9.3 7.9 0.86 10.0 2.2 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 GAX14706.1 - 9.4 6.1 12.0 2.4 8.0 5.9 2.1 1 1 1 2 2 2 0 Septum formation initiator PAP_fibrillin PF04755.12 GAX14707.1 - 8.6e-08 32.4 0.1 5.7e-05 23.2 0.0 3.0 2 1 0 2 2 2 2 PAP_fibrillin Gp49 PF05973.14 GAX14707.1 - 0.19 11.9 0.0 0.59 10.3 0.0 1.8 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) NUDIX PF00293.28 GAX14710.1 - 1.5e-13 51.0 0.1 2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Gly_transf_sug PF04488.15 GAX14711.1 - 1.7e-09 38.1 0.1 4.2e-09 36.9 0.1 1.9 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 GAX14711.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain UDPGT PF00201.18 GAX14713.1 - 0.00042 19.2 0.0 0.0011 17.8 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 GAX14713.1 - 0.034 14.1 0.1 0.075 13.0 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 RraA-like PF03737.15 GAX14713.1 - 0.047 13.8 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 Aldolase/RraA Trypsin PF00089.26 GAX14714.1 - 2.7e-46 158.2 0.2 3.3e-46 157.9 0.2 1.1 1 0 0 1 1 1 1 Trypsin RRM_9 PF18444.1 GAX14714.1 - 0.15 11.9 0.1 3.2 7.7 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif YqaJ PF09588.10 GAX14715.1 - 0.039 14.1 0.1 1.4 9.0 0.0 2.7 2 1 0 2 2 2 0 YqaJ-like viral recombinase domain Ehrlichia_rpt PF09528.10 GAX14715.1 - 0.064 12.7 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Nop14 PF04147.12 GAX14716.1 - 0.98 7.6 19.9 1.1 7.4 19.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAX14716.1 - 5.3 6.4 22.9 5.9 6.2 22.9 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAX14716.1 - 6.5 4.9 17.6 7.3 4.7 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GAX14716.1 - 9.5 5.4 20.1 11 5.2 20.1 1.0 1 0 0 1 1 1 0 BUD22 Ku PF02735.16 GAX14717.1 - 3.6e-26 92.1 0.0 1.2e-25 90.4 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain SAP PF02037.27 GAX14717.1 - 2.9e-07 30.1 5.0 3.3e-07 29.9 2.6 2.2 2 0 0 2 2 2 1 SAP domain Telomere_Sde2_2 PF13297.6 GAX14717.1 - 8.2e-06 25.4 0.8 3.2e-05 23.5 0.4 2.1 2 0 0 2 2 2 1 Telomere stability C-terminal Ku_C PF03730.14 GAX14717.1 - 0.00076 20.1 0.6 0.002 18.8 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm DNAPolymera_Pol PF11590.8 GAX14718.1 - 0.002 18.0 0.1 0.0041 17.0 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase catalytic subunit Pol ERG4_ERG24 PF01222.17 GAX14720.1 - 1.3e-70 238.4 15.9 1.5e-70 238.2 15.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ank_3 PF13606.6 GAX14721.1 - 1.6e-06 28.0 2.1 2.4 9.0 0.2 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 GAX14721.1 - 3.2e-06 27.6 0.8 0.01 16.4 0.3 3.6 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX14721.1 - 7.8e-06 26.1 0.2 0.14 12.5 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX14721.1 - 0.00016 21.9 1.4 1.7 9.2 0.4 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 GAX14721.1 - 0.0008 19.9 1.6 0.079 13.6 0.1 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) MarR_2 PF12802.7 GAX14721.1 - 0.04 13.8 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 MarR family PLU-1 PF08429.11 GAX14721.1 - 0.061 12.5 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 PLU-1-like protein UNC45-central PF11701.8 GAX14721.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central HgmA PF04209.13 GAX14722.1 - 5.4e-103 345.0 0.0 6.7e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Glyco_transf_25 PF01755.17 GAX14723.1 - 0.012 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) SANT_DAMP1_like PF16282.5 GAX14723.1 - 0.088 13.0 0.0 0.34 11.1 0.0 2.0 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 HEAT_2 PF13646.6 GAX14723.1 - 0.15 12.5 0.0 1.6 9.2 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats GST_N_3 PF13417.6 GAX14725.1 - 6.8e-20 71.3 0.0 3.2e-09 37.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX14725.1 - 1.4e-07 31.7 0.0 1.7e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX14725.1 - 0.0026 18.0 0.0 0.0077 16.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAX14725.1 - 0.006 16.8 0.0 0.072 13.3 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Amidohydro_1 PF01979.20 GAX14727.1 - 9.9e-09 34.9 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 GAX14727.1 - 0.00017 21.5 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase DUF3824 PF12868.7 GAX14728.1 - 0.019 15.6 0.6 0.028 15.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Pyr_redox_2 PF07992.14 GAX14729.1 - 1.3e-08 34.5 0.0 1.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX14729.1 - 0.0038 17.7 0.0 0.0082 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase LRR_6 PF13516.6 GAX14730.1 - 2.4e-05 24.0 22.5 0.028 14.4 0.0 7.4 9 0 0 9 9 9 2 Leucine Rich repeat LRR_8 PF13855.6 GAX14730.1 - 0.016 14.9 2.9 0.097 12.5 1.2 2.9 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 GAX14730.1 - 0.031 14.7 7.1 0.057 13.9 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Rhodanese PF00581.20 GAX14731.1 - 1.1e-11 45.2 0.0 2.2e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain Rhodanese PF00581.20 GAX14732.1 - 5.1e-21 75.2 0.0 4.9e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Choline_transpo PF04515.12 GAX14733.1 - 8.5e-67 225.7 24.8 8.5e-67 225.7 24.8 2.3 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF2615 PF11027.8 GAX14733.1 - 1.7 8.8 0.0 1.7 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) DUF21 PF01595.20 GAX14733.1 - 5 6.8 10.8 5.8 6.6 0.1 2.8 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain PUB PF09409.10 GAX14734.1 - 6.4e-17 61.3 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 GAX14734.1 - 4.6e-10 39.1 0.0 8.1e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX14734.1 - 0.00033 20.4 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like GerD PF17898.1 GAX14734.1 - 0.23 11.4 3.2 1.1 9.3 3.2 2.1 1 1 0 1 1 1 0 Spore germination GerD central core domain STI1 PF17830.1 GAX14734.1 - 6.8 6.7 20.2 1.6 8.7 1.4 3.2 2 1 1 3 3 3 0 STI1 domain HBD PF18534.1 GAX14736.1 - 4.4 7.5 13.2 2.2 8.4 2.9 3.6 3 1 0 3 3 3 0 Helical bundle domain DUF3909 PF13077.6 GAX14737.1 - 0.19 11.9 0.0 0.26 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) HSF_DNA-bind PF00447.17 GAX14738.1 - 3.6e-19 69.2 0.0 5.7e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Sad1_UNC PF07738.13 GAX14740.1 - 1.1e-25 90.2 0.2 1.8e-25 89.4 0.2 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 GAX14740.1 - 1.2e-07 31.9 0.0 2.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Peripla_BP_2 PF01497.18 GAX14741.1 - 1.6e-16 60.6 0.0 1.2e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein Bromo_TP PF07524.13 GAX14742.1 - 0.00071 19.5 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated Ku_C PF03730.14 GAX14742.1 - 0.074 13.8 0.2 0.14 12.8 0.2 1.5 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm DUF1572 PF07609.11 GAX14742.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) Spermine_synth PF01564.17 GAX14743.1 - 2.7e-34 118.2 0.0 5.2e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 GAX14743.1 - 1.4e-19 70.3 0.0 4.8e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine decarboxylase Methyltransf_12 PF08242.12 GAX14743.1 - 0.00041 21.0 0.0 0.0012 19.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX14743.1 - 0.013 16.2 0.0 0.036 14.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_7 PF03441.14 GAX14744.1 - 3.6e-43 147.4 2.3 5.7e-43 146.7 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAX14744.1 - 9.1e-28 97.3 0.1 1.6e-27 96.6 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase E7 PF00527.18 GAX14748.1 - 0.038 14.2 1.9 0.26 11.5 0.4 2.3 2 0 0 2 2 2 0 E7 protein, Early protein SR1P PF13790.6 GAX14748.1 - 7.6 6.7 7.8 40 4.4 1.9 3.4 3 0 0 3 3 3 0 SR1 protein HhH-GPD PF00730.25 GAX14754.1 - 1.8e-17 63.7 0.0 3.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 GAX14754.1 - 7.3e-13 48.5 1.5 8.4e-12 45.1 0.1 2.9 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.23 GAX14754.1 - 1e-05 25.1 0.0 3.2e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif Asp_Arg_Hydrox PF05118.15 GAX14759.1 - 1.1e-36 126.1 0.1 1.7e-36 125.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Raptor_N PF14538.6 GAX14759.1 - 0.088 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain UBX PF00789.20 GAX14761.1 - 2.2e-07 31.0 0.0 4.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Atg14 PF10186.9 GAX14761.1 - 0.0052 15.9 2.1 0.0096 15.0 2.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Nup54 PF13874.6 GAX14761.1 - 0.4 10.8 10.4 18 5.5 10.2 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 PRK PF00485.18 GAX14762.1 - 2e-71 239.8 0.0 3.1e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 GAX14762.1 - 0.12 12.8 0.0 0.61 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain ADH_zinc_N PF00107.26 GAX14763.1 - 6.6e-08 32.6 0.0 9.4e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX14763.1 - 0.006 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAX14763.1 - 0.0088 17.1 0.0 0.051 14.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Fic PF02661.18 GAX14764.1 - 3.7e-17 63.0 1.6 2e-16 60.7 0.1 2.8 2 0 0 2 2 2 1 Fic/DOC family zf-RING_2 PF13639.6 GAX14764.1 - 5.4e-07 29.8 7.7 5.4e-07 29.8 7.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 GAX14764.1 - 0.00011 22.4 4.7 0.00011 22.4 4.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAX14764.1 - 0.00017 21.4 5.2 0.00017 21.4 5.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX14764.1 - 0.0023 17.9 2.3 0.0023 17.9 2.3 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAX14764.1 - 0.011 15.5 9.4 0.011 15.5 9.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAX14764.1 - 0.41 10.8 8.7 1.3 9.2 8.7 1.9 1 0 0 1 1 1 0 RING-variant domain Ferritin PF00210.24 GAX14765.1 - 0.046 13.7 2.1 0.093 12.7 2.1 1.4 1 0 0 1 1 1 0 Ferritin-like domain RNase_P_p30 PF01876.16 GAX14766.1 - 6e-19 68.4 0.0 9.8e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 ParA PF10609.9 GAX14769.1 - 3.8e-74 249.3 0.6 2.5e-67 226.9 1.0 2.3 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 GAX14769.1 - 9.9e-14 51.7 0.0 2.1e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) FeS_assembly_P PF01883.19 GAX14769.1 - 1.8e-11 44.0 0.0 6.2e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 GAX14769.1 - 6.1e-10 39.2 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX14769.1 - 1.5e-09 38.1 0.9 2.5e-07 30.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 GAX14769.1 - 2.9e-08 33.3 0.0 4.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 GAX14769.1 - 0.0001 21.9 0.7 0.0025 17.3 0.7 2.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 GAX14769.1 - 0.0012 18.1 5.3 0.051 12.8 0.5 2.8 2 1 1 3 3 3 2 Anion-transporting ATPase Fer4_NifH PF00142.18 GAX14769.1 - 0.033 13.6 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 GAX14769.1 - 0.12 11.7 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 VirC1 protein Aminotran_1_2 PF00155.21 GAX14770.1 - 4.4e-53 180.7 0.0 5.1e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAX14770.1 - 0.065 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase CPSase_L_D2 PF02786.17 GAX14774.1 - 2.3e-73 246.2 0.1 3.5e-73 245.6 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 GAX14774.1 - 1.7e-28 98.9 0.0 4e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 GAX14774.1 - 1.7e-28 99.3 0.0 4.9e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 GAX14774.1 - 5.6e-14 51.7 1.0 1e-13 50.9 0.4 1.8 2 0 0 2 2 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAX14774.1 - 5.6e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAX14774.1 - 1.2e-06 28.2 0.0 2.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAX14774.1 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 GAX14774.1 - 2.4e-05 24.0 0.0 7.9e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAX14774.1 - 0.00019 21.2 0.0 0.004 16.9 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like ATPgrasp_ST PF14397.6 GAX14774.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 GAX14774.1 - 0.013 16.2 0.2 3.4 8.4 0.1 3.1 3 0 0 3 3 3 0 HlyD family secretion protein GCV_H PF01597.19 GAX14774.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Glycine cleavage H-protein ATP-grasp_3 PF02655.14 GAX14774.1 - 0.073 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ABC1 PF03109.16 GAX14774.1 - 0.093 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC1 family PTS_EIIA_1 PF00358.20 GAX14774.1 - 0.1 12.3 0.1 2.7 7.7 0.1 2.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 GAX14774.1 - 0.12 12.4 0.2 1.2 9.1 0.1 2.6 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain DUF4988 PF16378.5 GAX14774.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function MORN PF02493.20 GAX14775.1 - 1.2e-30 103.5 36.7 3.1e-06 26.8 0.7 7.4 7 0 0 7 7 7 6 MORN repeat DUF35_N PF12172.8 GAX14775.1 - 0.051 13.5 0.4 0.051 13.5 0.4 2.0 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3048_C PF17479.2 GAX14775.1 - 0.053 13.9 0.5 0.25 11.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain MORN PF02493.20 GAX14776.1 - 2.1e-30 102.8 35.7 2e-07 30.5 0.4 7.4 7 0 0 7 7 7 7 MORN repeat MORN_2 PF07661.13 GAX14776.1 - 1.7 9.1 11.4 8.4 7.0 0.6 4.4 3 1 0 3 3 3 0 MORN repeat variant dCMP_cyt_deam_1 PF00383.23 GAX14777.1 - 2.1e-14 53.2 0.0 9.1e-14 51.2 0.0 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX14777.1 - 0.00048 19.9 0.2 0.75 9.5 0.1 2.5 2 0 0 2 2 2 2 MafB19-like deaminase CRS1_YhbY PF01985.21 GAX14777.1 - 0.00078 19.6 0.3 0.0014 18.7 0.3 1.4 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Inv-AAD PF18785.1 GAX14777.1 - 0.0045 16.9 0.0 0.039 13.8 0.0 2.2 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase RAI1 PF08652.11 GAX14777.1 - 0.074 13.3 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease APOBEC_N PF08210.11 GAX14777.1 - 0.11 12.3 0.3 2 8.3 0.2 2.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain LysR_substrate PF03466.20 GAX14778.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain COX7B PF05392.11 GAX14778.1 - 0.17 11.6 0.1 0.44 10.2 0.1 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB cobW PF02492.19 GAX14779.1 - 8.7e-45 152.5 0.5 1.8e-44 151.5 0.5 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX14779.1 - 3.6e-14 52.4 0.0 1.4e-13 50.5 0.0 2.1 3 0 0 3 3 3 1 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 GAX14779.1 - 0.0098 15.9 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 GAX14779.1 - 0.012 14.6 0.2 0.07 12.2 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 GAX14779.1 - 0.045 14.1 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 GAX14779.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 GAX14779.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAX14779.1 - 0.069 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain PseudoU_synth_2 PF00849.22 GAX14780.1 - 1.6e-23 83.6 0.0 3.1e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase NTP_transf_3 PF12804.7 GAX14780.1 - 0.049 14.0 0.4 16 5.8 0.0 2.8 2 1 0 3 3 3 0 MobA-like NTP transferase domain DUF2802 PF10975.8 GAX14781.1 - 0.0064 16.6 0.8 0.18 12.0 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) DUF438 PF04282.13 GAX14781.1 - 0.023 14.7 0.1 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF438) PseudoU_synth_2 PF00849.22 GAX14782.1 - 1.4e-24 87.0 0.0 3.1e-24 85.9 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase Tfb4 PF03850.14 GAX14783.1 - 5.4e-49 167.2 0.8 7.6e-49 166.7 0.8 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C3HC4_3 PF13920.6 GAX14783.1 - 0.12 12.2 0.8 0.32 10.9 0.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YebG PF07130.12 GAX14784.1 - 0.19 11.6 0.0 2 8.4 0.0 2.7 2 1 1 3 3 3 0 YebG protein DUF1336 PF07059.12 GAX14785.1 - 9.6e-53 179.6 0.0 1.1e-52 179.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Tic22 PF04278.12 GAX14786.1 - 2.1e-11 43.7 0.2 6.9e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Tic22-like family Sterol_MT_C PF08498.10 GAX14787.1 - 6e-26 90.6 0.1 1.6e-25 89.2 0.1 1.7 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAX14787.1 - 6.7e-16 58.7 0.0 1.5e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX14787.1 - 1.5e-14 54.0 0.0 2.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX14787.1 - 8.6e-14 52.0 0.0 2.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX14787.1 - 3e-12 46.4 0.0 4.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAX14787.1 - 2e-09 37.5 0.0 5.5e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX14787.1 - 8.3e-09 36.1 0.0 2.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 GAX14787.1 - 0.0028 17.2 0.1 0.0053 16.3 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 GAX14787.1 - 0.0043 16.2 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAX14787.1 - 0.08 14.0 0.0 0.27 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Silic_transp PF03842.13 GAX14790.1 - 4.4e-222 737.9 6.8 5.5e-222 737.6 6.8 1.0 1 0 0 1 1 1 1 Silicon transporter PNTB PF02233.16 GAX14791.1 - 6.2e-164 546.3 33.3 7.1e-164 546.1 22.7 2.2 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAX14791.1 - 3e-70 235.8 4.5 3e-70 235.8 4.5 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAX14791.1 - 8.2e-36 123.3 0.0 2.2e-35 121.9 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAX14791.1 - 8.1e-28 96.7 1.4 8.1e-28 96.7 1.4 4.5 4 0 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 GAX14791.1 - 0.001 18.4 0.1 0.086 12.2 0.0 2.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAX14791.1 - 0.0066 16.4 4.4 0.013 15.5 0.2 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PFK PF00365.20 GAX14792.1 - 1.5e-56 191.8 0.0 1.9e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 GAX14792.1 - 0.027 14.1 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain MatE PF01554.18 GAX14793.1 - 5.4e-11 42.4 27.2 2.1e-10 40.5 8.0 3.4 2 2 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAX14793.1 - 9.3e-06 25.8 3.1 9.3e-06 25.8 3.1 3.5 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Prefoldin_2 PF01920.20 GAX14794.1 - 0.0017 18.3 0.7 0.002 18.0 0.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit FIN1 PF17300.2 GAX14794.1 - 0.024 14.2 0.4 0.028 13.9 0.4 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 BLOC1_2 PF10046.9 GAX14794.1 - 0.085 13.2 1.9 8 6.8 1.1 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glyco_hydro_38N PF01074.22 GAX14794.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain MerR-DNA-bind PF09278.11 GAX14794.1 - 0.15 12.6 5.7 1 9.9 4.4 2.0 1 1 1 2 2 2 0 MerR, DNA binding Annexin PF00191.20 GAX14795.1 - 3.3e-41 139.2 0.1 1.8e-09 37.5 0.0 4.2 4 0 0 4 4 4 4 Annexin YCII PF03795.14 GAX14797.1 - 0.0006 20.2 0.0 0.0022 18.3 0.0 1.9 2 0 0 2 2 2 1 YCII-related domain SMC_N PF02463.19 GAX14799.1 - 2.2e-20 73.0 2.7 7.3e-20 71.3 2.7 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAX14799.1 - 1.8e-19 71.0 0.9 1.8e-19 71.0 0.9 4.8 2 2 1 3 3 2 1 AAA domain AAA_21 PF13304.6 GAX14799.1 - 0.00019 21.3 1.2 0.0038 17.1 0.3 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX14799.1 - 0.0025 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Vps51 PF08700.11 GAX14799.1 - 0.01 15.9 0.1 0.01 15.9 0.1 4.1 3 1 0 3 3 3 1 Vps51/Vps67 AAA_27 PF13514.6 GAX14799.1 - 0.016 14.8 0.0 0.016 14.8 0.0 4.3 5 1 0 5 5 5 0 AAA domain DNA_mis_repair PF01119.19 GAX14799.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain FtsK_SpoIIIE PF01580.18 GAX14799.1 - 0.076 12.4 0.0 0.076 12.4 0.0 3.4 4 1 0 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GAX14799.1 - 0.088 13.3 0.1 0.088 13.3 0.1 4.7 4 2 0 4 4 3 0 ABC transporter AAA_16 PF13191.6 GAX14799.1 - 0.23 11.8 0.0 0.23 11.8 0.0 4.8 3 2 0 4 4 2 0 AAA ATPase domain BLOC1_2 PF10046.9 GAX14799.1 - 0.32 11.3 32.7 7.8 6.9 0.4 6.9 4 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mlh1_C PF16413.5 GAX14801.1 - 1.1e-51 175.8 0.1 7.5e-50 169.8 0.0 2.7 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 GAX14801.1 - 9.5e-17 60.8 0.1 1.9e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAX14801.1 - 1.1e-07 31.7 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAX14801.1 - 7.8e-05 23.1 0.0 0.00025 21.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SHMT PF00464.19 GAX14802.1 - 5.4e-175 581.8 0.0 6.3e-175 581.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 GAX14802.1 - 4.2e-05 23.0 0.0 7.4e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SelP_N PF04592.14 GAX14807.1 - 1.5 8.2 7.5 2.6 7.4 7.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Sulfotransfer_2 PF03567.14 GAX14809.1 - 0.00027 20.9 0.6 0.0007 19.6 0.6 1.8 1 1 0 1 1 1 1 Sulfotransferase family Gp_dh_C PF02800.20 GAX14810.1 - 6.2e-52 175.4 0.0 1.1e-46 158.3 0.0 2.4 1 1 1 2 2 2 2 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX14810.1 - 2.3e-35 121.0 0.2 4.3e-35 120.1 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX14810.1 - 0.0012 19.0 0.3 0.0054 16.8 0.3 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 GAX14810.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TgMIC1 PF11476.8 GAX14810.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 2-Hacid_dh_C PF02826.19 GAX14810.1 - 0.14 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_4 PF13637.6 GAX14811.1 - 1.5e-11 44.5 0.0 1.5e-06 28.7 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX14811.1 - 4.5e-10 40.0 0.0 1.6e-09 38.2 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX14811.1 - 5.4e-10 39.3 0.0 2.1e-05 24.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MRP-L20 PF12824.7 GAX14811.1 - 0.0087 16.2 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Ank_3 PF13606.6 GAX14811.1 - 0.021 15.3 0.0 2.1 9.2 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 GAX14811.1 - 0.032 14.7 0.0 12 6.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat DUF4692 PF15763.5 GAX14811.1 - 0.086 13.3 5.3 0.26 11.8 3.9 2.0 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) eIF3_p135 PF12807.7 GAX14812.1 - 0.032 14.2 1.0 0.04 13.9 1.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF4358 PF14270.6 GAX14812.1 - 0.075 13.3 1.2 0.21 11.9 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) LMBR1 PF04791.16 GAX14812.1 - 0.13 11.2 0.2 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_F PF12259.8 GAX14812.1 - 0.16 10.5 2.7 0.19 10.2 2.7 1.0 1 0 0 1 1 1 0 Baculovirus F protein DUF737 PF05300.11 GAX14812.1 - 1.9 8.8 10.9 0.9 9.9 1.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF737) Rimk_N PF18030.1 GAX14813.1 - 0.096 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 RimK PreATP-grasp domain Trypsin PF00089.26 GAX14814.1 - 2.5e-52 177.9 3.5 3e-52 177.6 3.5 1.1 1 0 0 1 1 1 1 Trypsin Abhydrolase_5 PF12695.7 GAX14816.1 - 6.6e-14 52.0 0.0 1.7e-12 47.4 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX14816.1 - 0.0083 15.4 0.0 0.03 13.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX14816.1 - 0.038 14.6 2.0 0.062 13.9 0.2 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_M8 PF01457.16 GAX14817.1 - 2.1e-12 46.6 0.0 3.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 GAX14817.1 - 0.13 12.1 0.3 0.77 9.6 0.3 2.0 1 1 0 1 1 1 0 Matrixin Peptidase_M8 PF01457.16 GAX14818.1 - 1.8e-11 43.4 0.0 2.6e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin TPR_2 PF07719.17 GAX14819.1 - 0.00013 21.8 4.0 0.0091 16.0 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX14819.1 - 0.0013 19.2 8.4 0.0049 17.3 0.6 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX14819.1 - 0.0025 18.1 7.3 3.8 7.9 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX14819.1 - 0.0032 18.1 9.4 0.011 16.5 0.1 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX14819.1 - 0.0056 17.2 6.8 0.15 12.8 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX14819.1 - 0.013 15.3 2.2 1.5 8.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX14819.1 - 0.035 14.1 1.8 0.11 12.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAX14819.1 - 0.051 13.9 0.6 0.2 12.0 0.5 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX14819.1 - 0.056 13.3 3.4 0.33 10.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat FAA_hydrolase_N PF09298.11 GAX14820.1 - 0.039 14.1 0.1 0.15 12.3 0.1 2.0 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal COPIIcoated_ERV PF07970.12 GAX14822.1 - 3.4e-68 229.8 0.0 5.2e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX14822.1 - 6.1e-20 71.4 0.4 1.5e-19 70.1 0.4 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Abhydrolase_6 PF12697.7 GAX14824.1 - 4.7e-07 30.6 3.4 4.7e-07 30.6 3.4 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX14824.1 - 8.3e-06 25.6 0.0 0.029 14.0 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX14824.1 - 0.00059 19.2 0.1 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 YfzA PF14118.6 GAX14824.1 - 0.0072 16.7 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 YfzA-like protein DUF3051 PF11252.8 GAX14825.1 - 0.0037 17.0 0.1 0.019 14.7 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3051) COX6C PF02937.15 GAX14825.1 - 0.15 12.2 0.6 0.39 10.9 0.6 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Img2 PF05046.14 GAX14826.1 - 6.7e-14 51.9 0.1 1.1e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Str_synth PF03088.16 GAX14827.1 - 1.2e-11 44.6 0.0 1.8e-10 40.8 0.0 2.5 1 1 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 GAX14827.1 - 6.4e-07 29.2 0.1 0.00048 19.8 0.0 3.6 2 1 2 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 GAX14827.1 - 0.0014 18.8 0.1 0.067 13.4 0.0 3.2 4 0 0 4 4 4 1 Arylesterase HMG_box PF00505.19 GAX14828.1 - 6.5e-45 151.4 17.3 1.8e-23 82.7 3.6 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX14828.1 - 9.7e-34 115.8 17.1 1.5e-17 63.9 3.8 2.6 2 0 0 2 2 2 2 HMG-box domain Rtt106 PF08512.12 GAX14828.1 - 4.1e-26 91.2 0.0 9.6e-26 90.0 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like POB3_N PF17292.2 GAX14828.1 - 5.9e-13 49.1 0.0 3.4e-10 40.2 0.0 2.8 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 GAX14828.1 - 7.6e-13 48.2 0.0 4.4e-12 45.7 0.0 2.4 2 1 1 3 3 3 1 Structure-specific recognition protein (SSRP1) YABBY PF04690.13 GAX14828.1 - 0.026 15.1 1.7 0.026 15.1 1.7 2.8 1 1 2 3 3 3 0 YABBY protein LtrA PF06772.11 GAX14829.1 - 4.7e-09 35.9 17.1 2e-06 27.3 7.0 2.6 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) FAM176 PF14851.6 GAX14829.1 - 0.01 15.5 3.8 0.063 12.9 0.0 2.5 1 1 1 2 2 2 0 FAM176 family Fer4_7 PF12838.7 GAX14829.1 - 0.07 13.7 0.3 0.15 12.6 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain TFIIE-A_C PF11521.8 GAX14829.1 - 6.1 7.2 9.4 0.55 10.6 0.9 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha HSF_DNA-bind PF00447.17 GAX14830.1 - 9.1e-16 58.3 0.4 2.7e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding DBP10CT PF08147.12 GAX14830.1 - 0.045 14.0 1.2 0.15 12.4 1.2 1.8 1 0 0 1 1 1 0 DBP10CT (NUC160) domain AAA PF00004.29 GAX14831.1 - 2.6e-28 99.1 0.0 8.3e-28 97.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX14831.1 - 6.3e-08 32.3 0.1 1.4e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 GAX14831.1 - 0.00035 20.0 0.0 0.00096 18.6 0.0 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX14831.1 - 0.0033 17.4 0.5 0.034 14.1 0.1 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX14831.1 - 0.011 15.9 0.0 0.035 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAX14831.1 - 0.025 14.9 2.9 0.081 13.2 0.5 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX14831.1 - 0.031 14.7 0.1 0.031 14.7 0.1 2.8 4 0 0 4 4 3 0 AAA ATPase domain AAA_33 PF13671.6 GAX14831.1 - 0.041 14.0 0.4 0.46 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 GAX14831.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 GAX14831.1 - 0.2 10.9 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 GAX14831.1 - 0.38 11.3 2.9 1.2 9.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Oxidored_molyb PF00174.19 GAX14832.1 - 2.4e-53 180.3 0.0 3.8e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAX14832.1 - 5.2e-25 88.1 1.0 1.2e-24 86.9 1.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 GAX14832.1 - 2.1e-13 50.2 0.0 3.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HSF_DNA-bind PF00447.17 GAX14833.1 - 5.6e-12 46.1 0.2 1.1e-11 45.2 0.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding BPL_LplA_LipB PF03099.19 GAX14834.1 - 8.6e-11 41.9 0.1 1.5e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3921 PF13060.6 GAX14834.1 - 0.084 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Tho2 PF11262.8 GAX14835.1 - 3.1e-71 240.0 0.0 3.1e-71 240.0 0.0 2.9 4 0 0 4 4 4 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 GAX14835.1 - 1.5e-38 132.9 7.7 4.8e-20 71.8 0.3 3.1 3 0 0 3 3 3 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 GAX14835.1 - 5.7e-27 93.6 0.0 1.7e-26 92.1 0.0 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF1978 PF09321.10 GAX14835.1 - 0.019 14.3 3.1 0.041 13.2 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) CBP4 PF07960.11 GAX14835.1 - 0.044 13.6 2.1 0.11 12.3 2.1 1.6 1 0 0 1 1 1 0 CBP4 APG6_N PF17675.1 GAX14835.1 - 0.079 13.5 7.5 1.3 9.5 2.3 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region CHCH PF06747.13 GAX14836.1 - 0.0017 18.5 0.3 0.0032 17.6 0.3 1.5 1 0 0 1 1 1 1 CHCH domain Mu-transpos_C PF09299.11 GAX14836.1 - 0.075 13.0 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Mu transposase, C-terminal ZapB PF06005.12 GAX14836.1 - 0.097 13.1 9.6 0.27 11.7 9.6 1.8 1 0 0 1 1 1 0 Cell division protein ZapB CLZ PF16526.5 GAX14836.1 - 0.34 11.3 5.8 0.64 10.4 5.8 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MCM_N PF14551.6 GAX14837.1 - 0.069 13.7 0.9 16 6.2 0.1 3.2 3 0 0 3 3 3 0 MCM N-terminal domain Pkinase PF00069.25 GAX14838.1 - 3e-36 125.2 0.1 8.6e-36 123.7 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14838.1 - 7e-13 48.5 0.0 1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 GAX14838.1 - 0.0012 18.4 0.1 0.003 17.2 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 GAX14838.1 - 0.0021 18.0 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 GAX14838.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 PqiA PF04403.13 GAX14839.1 - 6.9e-06 26.0 3.4 6.9e-06 26.0 3.4 3.2 4 0 0 4 4 4 2 Paraquat-inducible protein A zf-ACC PF17848.1 GAX14839.1 - 0.012 15.7 0.8 0.024 14.7 0.8 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain S-antigen PF05756.11 GAX14839.1 - 1.8 9.0 8.8 2.2 8.7 1.9 2.5 1 1 1 2 2 2 0 S-antigen protein DUF3439 PF11921.8 GAX14839.1 - 5.9 6.9 8.4 0.33 10.9 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Glyco_transf_22 PF03901.17 GAX14840.1 - 5e-37 128.1 21.5 6.7e-37 127.7 21.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Eapp_C PF10238.9 GAX14841.1 - 0.053 13.6 1.2 0.52 10.4 1.2 2.0 1 1 0 1 1 1 0 E2F-associated phosphoprotein AAA PF00004.29 GAX14842.1 - 1.3e-33 116.2 0.0 2.6e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX14842.1 - 2.7e-05 24.6 0.0 8e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX14842.1 - 3.8e-05 24.0 0.0 0.00053 20.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 GAX14842.1 - 0.00023 20.9 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 GAX14842.1 - 0.0004 20.6 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX14842.1 - 0.00043 20.3 0.0 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX14842.1 - 0.0013 18.5 0.0 0.0055 16.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GAX14842.1 - 0.0016 17.9 0.1 0.0041 16.5 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GAX14842.1 - 0.0019 18.2 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 GAX14842.1 - 0.002 17.9 0.1 0.019 14.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX14842.1 - 0.0056 17.2 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAX14842.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 GAX14842.1 - 0.022 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 GAX14842.1 - 0.023 15.1 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 GAX14842.1 - 0.06 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 GAX14842.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAX14842.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAX14842.1 - 0.09 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 GAX14842.1 - 0.095 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAX14842.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 GAX14842.1 - 0.14 11.7 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAX14842.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Thioredoxin_13 PF18401.1 GAX14843.1 - 0.046 13.6 1.0 1.3 8.9 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain TspO_MBR PF03073.15 GAX14844.1 - 5e-14 52.5 13.0 5e-14 52.5 13.0 1.9 2 1 0 2 2 2 1 TspO/MBR family Pkinase_Tyr PF07714.17 GAX14846.1 - 4.8e-15 55.6 0.0 7.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX14846.1 - 1.6e-14 53.9 0.0 2.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 GAX14846.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Ank_2 PF12796.7 GAX14848.1 - 5.1e-27 94.3 6.5 4.4e-15 56.0 0.2 3.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX14848.1 - 1.3e-23 83.0 3.5 3.9e-08 33.7 0.2 5.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX14848.1 - 1.3e-22 77.4 6.0 1.1e-05 25.4 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 GAX14848.1 - 1e-16 60.8 5.3 2.4e-05 24.5 0.0 4.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAX14848.1 - 3e-14 52.7 10.5 0.0025 18.2 0.0 6.0 7 0 0 7 7 7 3 Ankyrin repeat DUF3447 PF11929.8 GAX14848.1 - 0.011 15.7 1.3 0.13 12.2 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Shigella_OspC PF06128.11 GAX14848.1 - 0.13 12.0 0.3 22 4.7 0.1 2.7 2 1 1 3 3 3 0 Shigella flexneri OspC protein Nt_Gln_amidase PF09764.9 GAX14848.1 - 0.16 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal glutamine amidase UDG PF03167.19 GAX14849.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Cation_efflux PF01545.21 GAX14850.1 - 2.3e-15 56.9 6.1 6.7e-15 55.4 6.1 1.7 1 1 0 1 1 1 1 Cation efflux family SRTM1 PF15872.5 GAX14850.1 - 0.013 15.6 3.5 0.75 10.0 0.1 2.8 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Thr_synth_N PF14821.6 GAX14851.1 - 5.3e-27 93.9 0.0 3.2e-26 91.4 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 GAX14851.1 - 1.5e-14 54.1 0.0 6.8e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trypsin PF00089.26 GAX14852.1 - 5.1e-31 108.2 0.0 8.9e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX14852.1 - 0.048 14.6 0.0 0.15 13.0 0.0 1.8 1 0 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 GAX14852.1 - 8.3 4.8 17.7 11 4.3 17.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 NHL PF01436.21 GAX14853.1 - 0.96 9.6 6.3 1.8 8.8 0.0 4.1 4 0 0 4 4 4 0 NHL repeat Cation_efflux PF01545.21 GAX14854.1 - 2.4e-16 60.1 1.3 4e-16 59.3 1.3 1.3 1 0 0 1 1 1 1 Cation efflux family SRTM1 PF15872.5 GAX14854.1 - 2.6 8.2 5.3 3.6 7.8 0.2 3.0 2 1 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 GHMP_kinases_C PF08544.13 GAX14855.1 - 9e-16 58.0 0.6 2.3e-15 56.7 0.6 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAX14855.1 - 2.7e-09 37.1 0.7 2.7e-09 37.1 0.7 2.6 2 2 1 3 3 3 1 GHMP kinases N terminal domain Ntox34 PF15606.6 GAX14855.1 - 0.0095 16.0 0.0 0.043 13.9 0.0 2.0 2 0 0 2 2 2 1 Bacterial toxin 34 IKKbetaNEMObind PF12179.8 GAX14855.1 - 0.15 12.1 0.4 0.3 11.2 0.4 1.5 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF4336 PF14234.6 GAX14856.1 - 1e-14 54.5 0.0 2.9e-12 46.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) TPR_2 PF07719.17 GAX14858.1 - 0.0072 16.4 0.5 0.029 14.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX14858.1 - 0.0085 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX14858.1 - 0.054 13.8 0.3 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX14858.1 - 0.12 12.2 1.5 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat UbiA PF01040.18 GAX14859.1 - 2e-26 92.9 15.9 2.7e-26 92.4 15.5 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family PPR_2 PF13041.6 GAX14860.1 - 1.8e-33 114.5 0.2 2.4e-06 27.6 0.0 7.7 6 1 1 7 7 7 6 PPR repeat family PPR PF01535.20 GAX14860.1 - 7.4e-23 79.1 0.9 0.00025 21.1 0.0 9.2 9 1 0 9 9 9 4 PPR repeat PPR_3 PF13812.6 GAX14860.1 - 9.8e-21 73.6 4.3 1.4e-06 28.3 0.0 7.9 5 2 3 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX14860.1 - 6.5e-19 67.3 0.5 6.3e-05 22.6 0.0 8.8 7 2 2 9 9 9 3 PPR repeat PPR_long PF17177.4 GAX14860.1 - 4.7e-08 32.7 2.2 0.011 15.2 0.1 4.6 2 2 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP UPF0147 PF03685.13 GAX14860.1 - 0.089 12.9 0.2 0.53 10.4 0.0 2.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0147) Ank_2 PF12796.7 GAX14861.1 - 1.7e-17 63.7 0.9 6.7e-06 26.6 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX14861.1 - 2.7e-16 59.4 1.1 6.7e-07 29.5 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX14861.1 - 9e-11 42.1 2.1 4.2e-05 24.0 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX14861.1 - 1.5e-10 40.4 5.4 0.045 14.3 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ion_trans PF00520.31 GAX14861.1 - 1.8e-10 40.5 13.6 1.8e-10 40.5 13.6 1.6 2 0 0 2 2 2 1 Ion transport protein Ank PF00023.30 GAX14861.1 - 1.4e-08 34.8 7.6 0.043 14.3 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat CemA PF03040.14 GAX14861.1 - 0.021 14.7 0.4 0.021 14.7 0.4 1.7 2 0 0 2 2 2 0 CemA family DUF4618 PF15397.6 GAX14861.1 - 0.046 13.1 4.1 0.079 12.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) PAP2_C PF14360.6 GAX14862.1 - 1.2e-18 67.4 3.7 1.2e-18 67.4 3.7 3.8 3 1 1 4 4 4 1 PAP2 superfamily C-terminal PAP2 PF01569.21 GAX14862.1 - 0.00012 21.8 0.5 0.00012 21.8 0.5 3.8 4 1 1 5 5 5 1 PAP2 superfamily PAP2_3 PF14378.6 GAX14862.1 - 0.0014 18.4 7.7 0.0014 18.4 7.7 4.3 3 2 0 3 3 3 1 PAP2 superfamily CPP1-like PF11833.8 GAX14862.1 - 0.012 15.3 0.6 0.012 15.3 0.6 2.8 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Response_reg PF00072.24 GAX14863.1 - 3e-20 72.4 0.0 2.2e-17 63.2 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 GAX14863.1 - 2e-07 31.0 0.6 6e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 GAX14863.1 - 8.4e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M43 PF05572.13 GAX14864.1 - 5.2e-14 52.4 0.0 1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX14864.1 - 0.0014 19.1 0.1 0.0038 17.7 0.0 1.7 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX14864.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX14864.1 - 0.0016 18.3 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 GAX14864.1 - 0.0024 18.1 1.1 0.0056 16.9 1.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 GAX14864.1 - 0.014 14.4 4.3 0.025 13.5 2.0 2.0 2 0 0 2 2 2 0 Peptidase M66 Astacin PF01400.24 GAX14864.1 - 0.02 14.5 0.9 0.043 13.4 0.9 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 GAX14864.1 - 0.33 10.5 1.9 0.64 9.6 1.9 1.6 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Metallopep PF12044.8 GAX14864.1 - 0.56 8.7 2.6 1.1 7.8 2.6 1.4 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.5 GAX14864.1 - 0.67 9.1 3.4 1.2 8.2 3.4 1.4 1 0 0 1 1 1 0 Met-zincin IF-2B PF01008.17 GAX14865.1 - 4.3e-63 213.2 0.0 5.1e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 GAX14865.1 - 0.022 14.7 0.1 3.5 7.5 0.1 2.4 2 0 0 2 2 2 0 DeoR C terminal sensor domain RraA-like PF03737.15 GAX14866.1 - 1.2e-29 103.4 0.1 1.8e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA Salp15 PF12115.8 GAX14868.1 - 0.099 13.1 0.6 0.84 10.1 0.0 2.4 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation GAS PF13851.6 GAX14870.1 - 0.71 9.2 11.9 0.17 11.2 0.3 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PIN_8 PF18476.1 GAX14870.1 - 1.9 8.3 4.7 0.76 9.6 0.6 2.3 2 0 0 2 2 2 0 PIN like domain Ribosomal_L6e PF01159.19 GAX14871.1 - 7.6e-37 126.3 0.1 1e-36 125.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.29 GAX14871.1 - 0.051 13.6 0.2 0.29 11.1 0.3 2.2 2 0 0 2 2 2 0 KOW motif MFS_1 PF07690.16 GAX14872.1 - 7.7e-16 57.9 23.1 7.7e-16 57.9 23.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SusD-like PF12741.7 GAX14872.1 - 0.18 10.7 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein DUF2206 PF09971.9 GAX14872.1 - 0.46 9.2 3.3 0.28 9.9 0.9 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) FAM176 PF14851.6 GAX14872.1 - 3.1 7.5 5.0 13 5.4 0.0 2.5 2 1 0 2 2 2 0 FAM176 family NAD_kinase PF01513.21 GAX14874.1 - 2.3e-11 43.4 0.0 1.7e-08 34.1 0.0 2.5 3 0 0 3 3 3 2 ATP-NAD kinase DAGK_cat PF00781.24 GAX14874.1 - 0.0089 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain AhpC-TSA PF00578.21 GAX14875.1 - 1.5e-26 92.7 0.0 2.3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX14875.1 - 2.3e-09 37.1 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAX14875.1 - 1e-05 25.2 0.2 5.1e-05 23.0 0.0 2.3 2 1 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin DUF1989 PF09347.10 GAX14876.1 - 1.7e-55 187.2 0.2 2.1e-55 186.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Fumarate_red_C PF02300.17 GAX14877.1 - 6.6 6.8 9.1 0.18 11.9 0.6 2.7 2 0 0 2 2 2 0 Fumarate reductase subunit C HD_4 PF13328.6 GAX14878.1 - 1.2e-45 155.0 0.1 2.9e-45 153.8 0.1 1.7 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 GAX14878.1 - 1.8e-25 89.5 0.0 5.7e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins TGS PF02824.21 GAX14878.1 - 1.1e-14 54.2 0.0 5.1e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 TGS domain ACT_4 PF13291.6 GAX14878.1 - 3.8e-10 40.2 1.5 6.1e-10 39.5 0.5 2.0 2 0 0 2 2 2 1 ACT domain HD PF01966.22 GAX14878.1 - 7.4e-09 35.9 0.1 2.3e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 HD domain ThiS PF02597.20 GAX14878.1 - 0.0016 19.0 0.0 0.012 16.2 0.0 2.7 2 1 1 3 3 3 1 ThiS family Ub-Mut7C PF14451.6 GAX14878.1 - 0.0023 17.8 0.1 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Mut7-C ubiquitin Methyltransf_4 PF02390.17 GAX14879.1 - 1e-09 38.1 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 GAX14879.1 - 3.2e-06 27.0 0.0 6.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX14879.1 - 6.4e-05 23.6 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX14879.1 - 0.0089 16.8 0.0 0.078 13.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX14879.1 - 0.016 15.8 0.0 0.031 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAX14879.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M11 PF05548.11 GAX14880.1 - 2e-13 50.2 3.6 2.5e-12 46.6 3.6 2.0 1 1 0 1 1 1 1 Gametolysin peptidase M11 Metallopep PF12044.8 GAX14880.1 - 6e-05 21.8 1.6 9.6e-05 21.2 1.6 1.3 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 GAX14880.1 - 0.0016 18.9 0.1 0.0074 16.8 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like TMEM51 PF15345.6 GAX14880.1 - 0.0018 18.2 0.5 0.0042 17.0 0.2 1.7 2 0 0 2 2 2 1 Transmembrane protein 51 DUF1180 PF06679.12 GAX14880.1 - 0.01 16.3 1.4 0.021 15.2 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MAP17 PF15807.5 GAX14880.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM154 PF15102.6 GAX14880.1 - 0.03 14.2 0.5 0.081 12.8 0.0 1.9 2 1 0 2 2 2 0 TMEM154 protein family Reprolysin_5 PF13688.6 GAX14880.1 - 0.035 14.3 0.2 0.079 13.1 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 GAX14880.1 - 0.053 12.5 2.8 0.1 11.6 2.8 1.4 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 GAX14880.1 - 0.074 12.7 0.5 0.16 11.6 0.5 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like EphA2_TM PF14575.6 GAX14880.1 - 0.08 13.8 0.0 0.19 12.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M10 PF00413.24 GAX14880.1 - 0.089 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Matrixin DUF1885 PF08968.10 GAX14880.1 - 0.1 12.7 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) FAM176 PF14851.6 GAX14880.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.25 GAX14881.1 - 5.7e-62 209.5 0.0 6.7e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14881.1 - 1.6e-28 99.7 0.0 2.1e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX14881.1 - 7.4e-06 25.5 0.0 1.8e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAX14881.1 - 0.032 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX14881.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Imm7 PF15585.6 GAX14881.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 7 RIO1 PF01163.22 GAX14881.1 - 0.23 11.0 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 GAX14882.1 - 3.4e-44 149.3 3.6 7.5e-12 45.7 0.2 5.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX14882.1 - 1.3e-32 111.8 8.9 4.1e-08 33.6 0.1 7.6 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX14882.1 - 1e-30 102.3 8.0 0.0096 16.4 0.0 10.5 10 1 1 11 11 11 8 Ankyrin repeat Ank PF00023.30 GAX14882.1 - 5.3e-28 96.2 15.6 0.00034 20.9 0.0 11.0 9 2 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 GAX14882.1 - 2.4e-21 75.5 15.3 4.3e-06 26.9 0.2 7.9 1 1 7 9 9 9 8 Ankyrin repeats (many copies) Pkinase PF00069.25 GAX14883.1 - 2.2e-59 201.0 0.0 3.7e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX14883.1 - 2.2e-33 114.2 0.0 1.6e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX14883.1 - 5.1e-26 91.5 0.0 7.8e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX14883.1 - 3.2e-07 30.5 0.2 0.0066 16.4 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX14883.1 - 1.1e-05 25.0 0.0 4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAX14883.1 - 0.0003 20.2 0.0 0.00064 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 GAX14883.1 - 0.00091 19.6 0.5 0.21 12.1 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair DUF5470 PF17564.2 GAX14883.1 - 2.3 8.5 4.4 1.4 9.2 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5470) NUDIX PF00293.28 GAX14884.1 - 9.6e-07 28.9 0.0 1.7e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Pro_isomerase PF00160.21 GAX14885.1 - 2.8e-05 24.4 2.8 0.0027 18.0 0.0 3.4 3 1 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CoA_trans PF01144.23 GAX14885.1 - 0.066 12.6 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Coenzyme A transferase GPS2_interact PF15784.5 GAX14885.1 - 0.068 13.6 13.0 0.13 12.7 3.5 3.3 2 1 1 3 3 3 0 G-protein pathway suppressor 2-interacting domain PspA_IM30 PF04012.12 GAX14885.1 - 0.095 12.3 18.0 0.18 11.4 18.0 1.5 1 0 0 1 1 1 0 PspA/IM30 family zf-C4H2 PF10146.9 GAX14885.1 - 2 8.7 13.7 2.7 8.2 13.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein ABC_tran_CTD PF16326.5 GAX14885.1 - 2.5 8.4 37.4 1.7 9.0 2.0 4.7 3 1 1 4 4 4 0 ABC transporter C-terminal domain Cob_adeno_trans PF01923.18 GAX14885.1 - 2.6 8.2 7.7 0.6 10.2 3.7 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase TauE PF01925.19 GAX14886.1 - 3.7e-43 147.8 25.7 1.3e-19 70.8 12.2 2.0 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2076 PF09849.9 GAX14886.1 - 0.28 11.2 1.7 0.84 9.6 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) UPF0016 PF01169.19 GAX14886.1 - 1.1 9.7 16.4 0.12 12.7 5.3 3.3 2 2 0 2 2 2 0 Uncharacterized protein family UPF0016 Pirin_C PF05726.13 GAX14887.1 - 2.9e-22 79.0 0.1 5.2e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.16 GAX14887.1 - 0.0025 17.8 0.0 0.008 16.2 0.0 1.9 2 0 0 2 2 2 1 Pirin Mpp10 PF04006.12 GAX14888.1 - 0.22 9.9 0.0 0.32 9.4 0.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Abhydrolase_6 PF12697.7 GAX14889.1 - 2.5e-08 34.8 0.0 4.5e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family RTBV_P46 PF06216.11 GAX14889.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein G2BR PF18442.1 GAX14890.1 - 0.11 12.2 0.5 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) GSDH PF07995.11 GAX14891.1 - 0.00024 20.5 0.4 0.00062 19.2 0.4 1.7 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase HMG_box PF00505.19 GAX14892.1 - 5.1e-28 97.3 16.4 2.1e-18 66.5 3.5 2.8 2 1 1 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX14892.1 - 6.7e-22 77.9 12.9 7e-12 45.8 2.9 2.4 2 0 0 2 2 2 2 HMG-box domain Ccdc124 PF06244.12 GAX14892.1 - 0.74 10.4 17.3 0.052 14.1 7.2 3.1 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 GAX14892.1 - 4.2 7.4 17.2 2.3 8.2 3.2 3.7 3 1 0 3 3 3 0 HMG (high mobility group) box 5 DUF726 PF05277.12 GAX14893.1 - 1.3e-81 274.3 1.2 7.7e-31 107.3 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF726) G_glu_transpept PF01019.21 GAX14893.1 - 0.044 12.6 1.9 0.067 12.0 1.9 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Phage_holin_3_6 PF07332.11 GAX14893.1 - 3.5 7.7 14.2 4.8 7.3 11.7 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HMG_box PF00505.19 GAX14894.1 - 5e-28 97.3 12.5 1.1e-17 64.1 1.2 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX14894.1 - 5.8e-17 62.1 12.6 1.2e-08 35.4 1.2 2.4 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 GAX14894.1 - 0.071 13.1 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 CHDNT (NUC034) domain PAP_fibrillin PF04755.12 GAX14895.1 - 1.3e-13 51.4 0.1 2.7e-11 43.8 0.1 2.1 1 1 0 1 1 1 1 PAP_fibrillin PQQ_2 PF13360.6 GAX14896.1 - 6.7e-05 22.6 0.4 0.0049 16.5 0.1 2.5 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 GAX14896.1 - 0.0024 17.7 2.0 0.067 13.2 0.0 3.5 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_3 PF13570.6 GAX14896.1 - 0.015 15.8 10.7 0.52 10.9 0.2 4.6 4 1 0 4 4 4 0 PQQ-like domain E1-E2_ATPase PF00122.20 GAX14897.1 - 4.1e-39 134.0 5.5 4.1e-39 134.0 5.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAX14897.1 - 1.1e-38 133.7 0.4 2e-38 132.8 0.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAX14897.1 - 1.1e-08 35.3 0.0 4.1e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain OmpH PF03938.14 GAX14897.1 - 0.056 13.8 3.4 0.12 12.8 3.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Hydrolase_3 PF08282.12 GAX14897.1 - 0.086 12.6 4.2 0.66 9.7 0.1 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase ALMT PF11744.8 GAX14897.1 - 0.2 10.5 1.3 0.32 9.8 1.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PsbP PF01789.16 GAX14898.1 - 1e-15 58.2 0.0 1.3e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 PsbP Peptidase_S41 PF03572.18 GAX14901.1 - 4.5e-40 136.9 0.0 9.8e-40 135.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GAX14901.1 - 1.6e-08 34.3 0.0 4.4e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX14901.1 - 1.6e-05 25.2 1.5 2.7e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX14901.1 - 0.0016 18.7 0.0 0.006 16.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain RhoGEF PF00621.20 GAX14901.1 - 0.0074 16.5 0.1 0.6 10.3 0.1 2.3 2 0 0 2 2 2 1 RhoGEF domain Myc_N PF01056.18 GAX14901.1 - 0.059 13.3 0.6 0.1 12.5 0.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region LSDAT_prok PF18171.1 GAX14901.1 - 0.083 12.1 0.0 0.22 10.7 0.0 1.7 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Yip1 PF04893.17 GAX14903.1 - 1.3e-10 41.3 5.9 2e-10 40.6 5.9 1.4 1 0 0 1 1 1 1 Yip1 domain Pex14_N PF04695.13 GAX14903.1 - 9.1 6.9 20.9 12 6.5 18.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region adh_short PF00106.25 GAX14904.1 - 9.5e-29 100.2 0.0 5.1e-25 88.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX14904.1 - 8.7e-17 61.5 0.0 2.1e-14 53.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX14904.1 - 3.2e-05 23.9 0.0 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAX14905.1 - 6.1e-30 104.1 0.0 1.3e-22 80.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX14905.1 - 9.1e-19 67.9 0.0 1.5e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX14905.1 - 3.4e-05 23.8 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2344 PF10105.9 GAX14905.1 - 0.012 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Epimerase PF01370.21 GAX14905.1 - 0.061 12.8 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Flavi_glycoprot PF00869.20 GAX14905.1 - 0.067 12.4 0.0 0.099 11.8 0.0 1.4 1 1 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains adh_short PF00106.25 GAX14906.1 - 7.2e-32 110.4 0.0 9.1e-23 80.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX14906.1 - 7.6e-22 78.0 0.0 4.3e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX14906.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Protamine_3 PF08188.11 GAX14907.1 - 0.019 15.2 0.3 0.98 9.7 0.1 2.3 2 0 0 2 2 2 0 Spermatozal protamine family TALPID3 PF15324.6 GAX14909.1 - 1.9 6.1 9.0 2.3 5.8 9.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target PT PF04886.12 GAX14910.1 - 0.024 14.2 53.5 0.077 12.6 14.8 4.9 2 1 1 3 3 3 0 PT repeat Cu-binding_MopE PF11617.8 GAX14911.1 - 2.1 8.6 10.3 0.64 10.2 0.5 3.4 3 0 0 3 3 3 0 Putative metal-binding motif SET PF00856.28 GAX14912.1 - 8.1e-13 49.1 0.0 2.7e-06 27.9 0.0 4.3 2 2 1 3 3 3 3 SET domain L27_2 PF09045.10 GAX14913.1 - 0.35 10.8 1.7 0.61 10.1 0.4 2.0 2 0 0 2 2 2 0 L27_2 Kinesin PF00225.23 GAX14914.1 - 1e-102 343.5 0.1 1e-102 343.5 0.1 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX14914.1 - 8.2e-30 103.7 14.0 3.9e-29 101.5 0.0 4.2 3 1 1 4 4 4 2 Microtubule binding ATG16 PF08614.11 GAX14914.1 - 0.0057 16.9 30.8 0.0057 16.9 30.8 8.6 3 3 4 7 7 7 3 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 GAX14914.1 - 0.012 15.7 3.0 0.012 15.7 3.0 10.7 6 2 4 11 11 11 0 TPR/MLP1/MLP2-like protein DUF846 PF05832.12 GAX14915.1 - 2.4e-48 163.7 10.0 3.1e-48 163.3 10.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Phage_holin_2_4 PF16082.5 GAX14915.1 - 0.085 12.6 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4191 PF13829.6 GAX14915.1 - 3.1 7.1 7.0 0.22 10.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) SpoU_methylase PF00588.19 GAX14916.1 - 7.8e-26 90.9 0.0 1.8e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family UPF0139 PF03669.13 GAX14916.1 - 0.084 12.7 0.1 0.31 10.9 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) PGI PF00342.19 GAX14918.1 - 2.7e-43 148.3 0.0 2.7e-40 138.4 0.0 3.3 2 1 0 2 2 2 2 Phosphoglucose isomerase DUF1499 PF07386.11 GAX14919.1 - 1.8e-22 80.1 0.0 2.4e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Methyltr_RsmB-F PF01189.17 GAX14920.1 - 3.9e-21 75.6 0.0 1.3e-11 44.5 0.0 3.2 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 GAX14920.1 - 7e-06 25.9 0.0 0.0067 16.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.19 GAX14920.1 - 0.00066 19.8 0.1 0.0059 16.7 0.1 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 GAX14920.1 - 0.003 18.2 0.0 0.02 15.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX14920.1 - 0.034 13.5 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltr_RsmF_N PF17125.5 GAX14920.1 - 0.035 14.6 0.0 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_23 PF13489.6 GAX14920.1 - 0.049 13.5 0.0 1.2 9.0 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF3593 PF12159.8 GAX14921.1 - 1.3e-31 108.4 0.2 1.3e-31 108.4 0.2 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3593) DUF2499 PF10693.9 GAX14921.1 - 1.9e-28 98.6 5.9 3.1e-28 97.9 3.3 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2499) DUF5379 PF17350.2 GAX14921.1 - 0.044 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5379) PspA_IM30 PF04012.12 GAX14922.1 - 2.3e-07 30.7 12.4 3.5e-07 30.0 12.4 1.3 1 0 0 1 1 1 1 PspA/IM30 family DUF1771 PF08590.10 GAX14922.1 - 0.006 16.9 0.7 0.016 15.6 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) GPAT_N PF14829.6 GAX14922.1 - 0.025 14.5 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Gly-zipper_YMGG PF13441.6 GAX14922.1 - 0.1 12.4 12.0 0.2 11.4 12.0 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Romo1 PF10247.9 GAX14922.1 - 0.77 10.2 4.7 2.4 8.6 4.7 1.9 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 FliD_N PF02465.18 GAX14922.1 - 1.8 9.3 4.0 23 5.8 4.0 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus kleA_kleC PF17383.2 GAX14922.1 - 2.8 8.3 5.7 1.4 9.3 1.4 2.3 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A DUF1681 PF07933.14 GAX14923.1 - 8.1e-36 123.0 0.0 9.6e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) TAT_ubiq PF07706.12 GAX14923.1 - 0.11 12.7 0.4 0.57 10.5 0.2 2.2 2 0 0 2 2 2 0 Aminotransferase ubiquitination site SRP19 PF01922.17 GAX14924.1 - 2.7e-23 82.7 0.6 4.5e-23 82.0 0.0 1.6 2 0 0 2 2 2 1 SRP19 protein KA1 PF02149.19 GAX14925.1 - 0.087 12.6 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Kinase associated domain 1 RITA PF17066.5 GAX14926.1 - 0.085 12.4 4.9 0.68 9.5 3.8 2.1 2 0 0 2 2 2 0 RBPJ-interacting and tubulin associated protein Pkinase PF00069.25 GAX14927.1 - 2.6e-41 141.7 0.0 3.7e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14927.1 - 5.9e-20 71.6 0.0 2.6e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX14927.1 - 4.8e-05 23.4 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX14927.1 - 0.0032 16.8 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX14927.1 - 0.009 14.8 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAX14927.1 - 0.024 13.6 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 GAX14927.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 GAX14928.1 - 2.7e-45 154.8 0.0 3.7e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14928.1 - 1.4e-16 60.5 0.0 1e-15 57.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX14928.1 - 1.3e-05 25.3 0.1 6.2e-05 23.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX14928.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAX14928.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX14928.1 - 0.061 12.1 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Mog1 PF04603.12 GAX14929.1 - 1.7e-30 106.2 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein RNase_PH PF01138.21 GAX14930.1 - 1.1e-13 51.8 0.1 1.9e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Surfac_D-trimer PF09006.11 GAX14932.1 - 0.051 13.5 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation LRR_4 PF12799.7 GAX14933.1 - 2.5e-16 59.5 7.9 0.00011 22.5 0.1 4.7 5 0 0 5 5 4 3 Leucine Rich repeats (2 copies) Roc PF08477.13 GAX14933.1 - 5.2e-15 55.7 0.1 1.5e-13 51.0 0.1 3.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 GAX14933.1 - 8e-15 54.4 9.5 1.6e-09 37.4 2.3 3.6 1 1 2 3 3 3 3 Leucine rich repeat Trypsin_2 PF13365.6 GAX14933.1 - 1.9e-13 51.6 0.0 4.8e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain COR PF16095.5 GAX14933.1 - 1.3e-08 34.9 0.0 0.0022 17.8 0.0 3.2 3 0 0 3 3 3 2 C-terminal of Roc, COR, domain LRR_1 PF00560.33 GAX14933.1 - 3.7e-07 29.8 2.6 2.9 8.8 0.1 6.2 5 1 0 5 5 5 1 Leucine Rich Repeat Ras PF00071.22 GAX14933.1 - 2.8e-06 27.0 0.1 1.9e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAX14933.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX14933.1 - 0.0031 16.9 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAX14933.1 - 0.02 14.4 0.8 0.67 9.4 0.8 2.4 1 1 0 1 1 1 0 ADP-ribosylation factor family LRR_6 PF13516.6 GAX14933.1 - 0.042 13.9 9.5 67 3.9 0.1 5.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.6 GAX14933.1 - 0.053 13.0 1.8 0.86 9.1 0.1 2.7 1 1 2 3 3 3 0 Leucine-rich repeat Thioredoxin PF00085.20 GAX14934.1 - 0.00052 20.0 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF3311 PF11755.8 GAX14935.1 - 0.18 11.8 0.5 0.33 10.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Peptidase_M24 PF00557.24 GAX14936.1 - 6.9e-51 172.9 0.0 8.7e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAX14936.1 - 7.6e-22 77.3 0.0 1.4e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Chordopox_A13L PF05961.11 GAX14937.1 - 0.074 13.3 0.2 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus A13L protein BRE1 PF08647.11 GAX14938.1 - 0.0049 16.9 18.1 0.0049 16.9 18.1 5.5 3 2 1 4 4 4 1 BRE1 E3 ubiquitin ligase MSL1_dimer PF16801.5 GAX14938.1 - 0.19 11.5 3.0 2.7 7.8 0.7 3.1 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 DUF720 PF05302.11 GAX14938.1 - 5.1 7.0 8.1 3.5 7.5 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF720) ArsA_ATPase PF02374.15 GAX14939.1 - 1.2e-102 343.2 0.1 1.5e-90 303.5 0.0 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 GAX14939.1 - 7.2e-14 52.1 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX14939.1 - 9.1e-12 45.1 0.0 2.2e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 GAX14939.1 - 1.7e-06 27.7 0.1 1.2e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 GAX14939.1 - 7.6e-06 25.5 1.4 0.0014 18.2 0.2 2.9 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 GAX14939.1 - 0.00011 21.9 0.3 0.0078 15.9 0.2 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 GAX14939.1 - 0.0014 18.2 0.0 0.0044 16.5 0.0 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GAX14939.1 - 0.0093 15.6 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NAD_binding_9 PF13454.6 GAX14939.1 - 0.098 12.6 0.0 0.91 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2868 PF11067.8 GAX14939.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PhoH PF02562.16 GAX14939.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein VirC1 PF07015.11 GAX14939.1 - 0.12 11.7 0.1 0.27 10.5 0.1 1.7 1 1 0 1 1 1 0 VirC1 protein NB-ARC PF00931.22 GAX14939.1 - 0.18 11.0 0.1 0.44 9.7 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain MipZ PF09140.11 GAX14939.1 - 0.26 10.5 0.7 2 7.7 0.1 2.1 1 1 1 2 2 2 0 ATPase MipZ Peptidase_M16_C PF05193.21 GAX14941.1 - 1.1e-25 90.7 0.0 3.4e-25 89.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAX14941.1 - 2.3e-20 73.1 0.0 1e-19 71.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PX PF00787.24 GAX14943.1 - 0.052 13.5 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 PX domain SOG2 PF10428.9 GAX14944.1 - 5.1 6.2 17.0 6.8 5.8 17.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Bac_globin PF01152.21 GAX14945.1 - 1.8e-08 34.5 0.1 2.5e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Bacterial-like globin EzrA PF06160.12 GAX14946.1 - 1.1 7.3 13.4 0.091 10.9 2.8 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF724 PF05266.14 GAX14946.1 - 1.5 8.6 17.0 3.6 7.4 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 GAX14946.1 - 2.8 8.5 30.3 0.14 12.7 7.5 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region RasGAP_C PF03836.15 GAX14946.1 - 6.8 6.8 15.3 1.2 9.3 4.5 2.5 2 0 0 2 2 2 0 RasGAP C-terminus TMPIT PF07851.13 GAX14946.1 - 9.3 5.4 14.0 4.4 6.5 2.5 2.2 2 0 0 2 2 2 0 TMPIT-like protein NACHT PF05729.12 GAX14947.1 - 0.0025 17.8 0.6 0.0073 16.2 0.6 2.0 1 1 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.18 GAX14947.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mito_carr PF00153.27 GAX14948.1 - 9.5e-05 22.3 0.7 2.2 8.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein AP3D1 PF06375.11 GAX14949.1 - 0.015 15.6 9.5 0.019 15.2 9.5 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 E2F_TDP PF02319.20 GAX14950.1 - 2.7e-30 104.2 0.2 1.4e-17 63.5 0.2 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain SdiA-regulated PF06977.11 GAX14950.1 - 0.047 12.9 0.2 0.077 12.2 0.2 1.2 1 0 0 1 1 1 0 SdiA-regulated TrmB PF01978.19 GAX14950.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TPR_12 PF13424.6 GAX14951.1 - 5e-11 42.7 4.8 6.8e-08 32.7 0.7 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14951.1 - 1.9e-06 27.5 3.4 1.2 9.4 0.4 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX14951.1 - 1.3e-05 24.9 5.0 0.32 11.1 0.3 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX14951.1 - 0.00015 21.5 1.2 0.29 11.0 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX14951.1 - 0.00072 19.3 2.7 0.12 12.3 0.2 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX14951.1 - 0.019 15.2 4.5 3.5 8.1 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX14951.1 - 0.048 14.3 0.6 50 4.8 0.2 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat YfkD PF14167.6 GAX14951.1 - 0.092 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 YfkD-like protein TPR_14 PF13428.6 GAX14951.1 - 0.097 13.5 5.8 8.5 7.5 0.1 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat NUDIX PF00293.28 GAX14952.1 - 1.1e-09 38.4 0.0 2.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Methyltransf_32 PF13679.6 GAX14952.1 - 0.019 15.0 2.4 0.037 14.0 0.6 2.3 2 1 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.27 GAX14953.1 - 0.01 15.7 7.6 0.099 12.6 0.1 3.8 4 1 0 4 4 4 0 Mitochondrial carrier protein ETRAMP PF09716.10 GAX14953.1 - 0.03 14.4 0.0 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CNDH2_C PF16858.5 GAX14954.1 - 0.043 13.7 2.3 0.087 12.7 2.3 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4942 PF13708.6 GAX14956.1 - 0.093 12.7 0.3 9.7 6.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4942) CSRNP_N PF16019.5 GAX14956.1 - 0.13 12.1 5.3 0.21 11.5 0.8 2.5 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus HXXSHH PF07586.11 GAX14956.1 - 0.52 9.8 4.0 1 8.9 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) PPR_2 PF13041.6 GAX14958.1 - 2.9e-28 97.8 3.6 0.00057 20.0 0.0 14.2 11 5 4 15 15 15 5 PPR repeat family PPR_1 PF12854.7 GAX14958.1 - 4.9e-20 70.9 0.0 0.021 14.5 0.0 11.7 12 1 0 12 12 12 5 PPR repeat PPR_3 PF13812.6 GAX14958.1 - 1.5e-17 63.4 0.0 0.0056 16.7 0.0 10.0 7 2 3 10 10 10 4 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX14958.1 - 2.4e-12 46.7 16.0 0.0046 16.4 0.0 6.2 2 2 6 8 8 8 7 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX14958.1 - 1e-11 44.2 12.3 0.4 11.0 0.0 13.1 13 2 0 13 13 13 3 PPR repeat UPF0004 PF00919.20 GAX14958.1 - 0.034 14.2 0.5 0.48 10.5 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein family UPF0004 E7 PF00527.18 GAX14958.1 - 0.086 13.0 0.2 24 5.2 0.1 2.7 2 0 0 2 2 2 0 E7 protein, Early protein TC1 PF15063.6 GAX14958.1 - 0.086 12.7 1.3 9.8 6.1 0.1 3.9 3 1 0 3 3 3 0 Thyroid cancer protein 1 Aminotran_4 PF01063.19 GAX14960.1 - 3.5e-34 118.6 0.0 4.5e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV PsbP PF01789.16 GAX14961.1 - 9.8e-07 29.0 0.1 0.0001 22.5 0.0 2.4 2 1 0 2 2 2 2 PsbP zf-MYND PF01753.18 GAX14962.1 - 2.1e-07 30.9 8.7 2.1e-07 30.9 8.7 2.0 2 0 0 2 2 2 1 MYND finger F-box PF00646.33 GAX14962.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 GAX14962.1 - 0.065 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 GAX14962.1 - 0.065 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box PEP_mutase PF13714.6 GAX14963.1 - 2.6e-44 151.5 0.0 3.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAX14963.1 - 6.1e-12 44.8 0.0 8.4e-12 44.3 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 GAX14963.1 - 0.0013 18.2 0.0 0.0084 15.5 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase TPR_19 PF14559.6 GAX14964.1 - 1.8e-22 79.6 9.2 0.00019 21.9 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX14964.1 - 7.9e-21 72.4 22.8 0.0019 18.2 0.2 10.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX14964.1 - 5.1e-19 67.2 6.5 0.00088 19.0 0.0 8.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX14964.1 - 4.7e-18 63.8 11.1 0.0084 16.2 0.1 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAX14964.1 - 4.1e-17 61.4 28.3 0.00048 20.7 0.3 9.2 8 3 2 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 GAX14964.1 - 4.6e-12 45.4 7.9 0.0024 17.5 0.1 7.1 7 0 0 7 7 7 3 TPR repeat TPR_12 PF13424.6 GAX14964.1 - 5.6e-11 42.6 21.5 0.15 12.4 0.1 8.2 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX14964.1 - 2.3e-08 34.5 20.4 0.013 16.1 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX14964.1 - 1.8e-05 24.8 0.2 67 4.2 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX14964.1 - 3.7e-05 23.9 19.0 4.3 7.6 3.7 7.1 6 1 2 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GAX14964.1 - 0.00029 20.9 15.5 0.43 10.8 1.1 6.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX14964.1 - 0.00038 20.3 15.0 4.8 7.5 0.3 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX14964.1 - 0.0012 19.4 10.1 19 6.1 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat PPR PF01535.20 GAX14964.1 - 0.0017 18.5 0.1 1.6 9.1 0.0 4.0 4 0 0 4 4 4 1 PPR repeat NRBF2_MIT PF17169.4 GAX14964.1 - 0.0019 18.4 0.4 4.4 7.6 0.1 3.9 3 0 0 3 3 3 1 MIT domain of nuclear receptor-binding factor 2 TPR_10 PF13374.6 GAX14964.1 - 0.014 15.2 2.2 2.5 8.1 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat GlutR_N PF05201.15 GAX14965.1 - 2.1e-40 137.9 0.1 4.1e-40 136.9 0.1 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 GAX14965.1 - 3.1e-32 111.5 0.0 7.2e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 GAX14965.1 - 1.9e-23 82.7 2.6 1.9e-23 82.7 2.6 1.9 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain OCD_Mu_crystall PF02423.15 GAX14965.1 - 0.0012 17.8 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 GAX14965.1 - 0.0018 18.8 0.0 0.0086 16.6 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent betaPIX_CC PF16523.5 GAX14965.1 - 0.002 17.9 1.0 0.0065 16.3 1.0 1.8 1 0 0 1 1 1 1 betaPIX coiled coil Sel1 PF08238.12 GAX14966.1 - 1.9e-19 69.6 0.0 0.00031 21.3 0.0 5.4 5 0 0 5 5 5 4 Sel1 repeat DEK_C PF08766.11 GAX14967.1 - 0.00011 22.1 4.3 0.00027 20.8 4.3 1.7 1 0 0 1 1 1 1 DEK C terminal domain DUF4845 PF16137.5 GAX14967.1 - 0.049 14.5 1.3 0.049 14.5 1.3 2.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4845) HARE-HTH PF05066.13 GAX14967.1 - 0.066 13.6 1.4 0.075 13.4 0.4 1.7 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain PGA2 PF07543.12 GAX14967.1 - 0.21 11.6 7.3 0.35 10.8 7.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 FKBP_N PF01346.18 GAX14967.1 - 0.47 11.4 6.0 0.35 11.9 1.1 2.2 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase NACHT_N PF17100.5 GAX14967.1 - 0.48 10.3 4.8 0.69 9.7 4.8 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Rhodanese_C PF12368.8 GAX14968.1 - 2e-12 47.3 7.1 3.8e-12 46.4 7.1 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 GAX14968.1 - 7.4e-11 42.3 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GAX14968.1 - 1.2e-06 29.0 0.0 4.5e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Rhodanese-like domain RRM_1 PF00076.22 GAX14968.1 - 0.032 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nefa_Nip30_N PF10187.9 GAX14969.1 - 5.6e-10 39.5 4.9 5.6e-10 39.5 4.9 2.0 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 GAX14969.1 - 0.0086 15.7 12.7 0.01 15.5 12.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) bZIP_1 PF00170.21 GAX14970.1 - 3e-09 36.8 8.5 6.4e-09 35.8 8.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX14970.1 - 1.2e-06 28.5 7.1 2.6e-06 27.4 7.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAX14970.1 - 0.0022 18.5 3.0 0.0049 17.4 3.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 GAX14971.1 - 9.8e-08 32.0 10.4 1.8e-07 31.1 10.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX14971.1 - 9.5e-07 28.8 12.0 9.5e-07 28.8 12.0 1.8 2 0 0 2 2 2 1 Basic region leucine zipper RebB PF11747.8 GAX14971.1 - 0.48 10.6 5.1 0.79 9.9 2.9 2.1 2 0 0 2 2 2 0 Killing trait CBFD_NFYB_HMF PF00808.23 GAX14972.1 - 2.2e-10 40.7 0.3 3.7e-10 39.9 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX14972.1 - 2.3e-05 24.8 0.8 2.9e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SDA1 PF05285.12 GAX14972.1 - 0.1 12.0 16.2 0.11 11.9 16.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAX14972.1 - 0.32 9.2 10.3 0.34 9.2 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAX14972.1 - 1.4 7.0 19.5 1.6 6.8 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GAX14972.1 - 4.3 7.6 18.6 6.7 7.0 18.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated UQ_con PF00179.26 GAX14973.1 - 1.1e-48 164.5 0.0 1.2e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX14973.1 - 0.008 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B eIF-5_eIF-2B PF01873.17 GAX14974.1 - 1.4e-33 115.3 0.0 4e-33 113.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 GAX14974.1 - 2.2e-17 63.0 1.4 2.2e-17 63.0 1.4 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon AAA_11 PF13086.6 GAX14974.1 - 0.0025 17.7 3.0 0.011 15.6 2.0 2.0 2 0 0 2 2 2 1 AAA domain DDHD PF02862.17 GAX14974.1 - 0.12 12.5 4.9 0.26 11.4 4.7 1.5 2 0 0 2 2 2 0 DDHD domain Zip PF02535.22 GAX14974.1 - 0.97 8.6 4.1 1.2 8.3 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF812 PF05667.11 GAX14975.1 - 0.00077 18.5 4.5 0.00089 18.3 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Prp19 PF08606.11 GAX14975.1 - 0.016 15.2 1.0 0.038 14.0 1.0 1.8 1 1 0 1 1 1 0 Prp19/Pso4-like TMEM192 PF14802.6 GAX14975.1 - 0.027 13.6 0.0 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 TMEM192 family Herpes_UL14 PF03580.14 GAX14975.1 - 0.036 14.3 5.1 0.063 13.5 4.4 1.6 1 1 1 2 2 2 0 Herpesvirus UL14-like protein KELK PF15796.5 GAX14975.1 - 0.037 14.5 8.2 0.037 14.5 8.2 1.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KLRAQ PF10205.9 GAX14975.1 - 0.068 13.4 7.7 0.11 12.7 7.7 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 GAX14975.1 - 0.23 10.3 11.2 0.29 10.0 11.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 GAX14975.1 - 0.23 9.3 4.6 0.25 9.2 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM76 PF16046.5 GAX14975.1 - 0.26 10.6 6.0 0.3 10.4 6.0 1.1 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 GAX14975.1 - 0.46 11.1 5.9 4.3 8.0 3.8 2.7 1 1 1 2 2 2 0 SlyX YabA PF06156.13 GAX14975.1 - 0.69 10.6 9.1 0.97 10.1 8.2 1.7 1 1 0 1 1 1 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 GAX14975.1 - 0.78 9.3 11.1 1 8.9 11.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 LMBR1 PF04791.16 GAX14975.1 - 0.8 8.5 3.3 0.92 8.3 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.11 GAX14975.1 - 1.4 9.0 9.9 1.9 8.5 9.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 GAX14975.1 - 1.7 9.2 13.6 3.7 8.1 11.9 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 GAX14975.1 - 2.3 8.3 7.6 3.5 7.7 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 GAX14975.1 - 5.9 6.1 10.4 9.5 5.4 10.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) VPS13 PF16908.5 GAX14976.1 - 5.2e-34 118.1 0.0 1.2e-31 110.3 0.0 3.0 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 GAX14976.1 - 1.2e-17 64.1 0.3 1.1e-16 61.0 0.0 2.8 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 GAX14976.1 - 2.8e-13 49.8 0.0 4.2e-11 42.7 0.0 3.5 3 1 0 3 3 3 1 Repeating coiled region of VPS13 VPS13_C PF16909.5 GAX14976.1 - 0.0033 17.2 0.0 0.0033 17.2 0.0 3.6 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal Apt1 PF10351.9 GAX14976.1 - 0.014 14.3 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lysine_decarbox PF03641.14 GAX14978.1 - 7.7e-26 90.7 0.0 1.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 GAX14978.1 - 3.8e-14 52.6 0.0 1.9e-13 50.3 0.0 2.1 1 1 0 1 1 1 1 SLOG cluster4 family ABC_tran PF00005.27 GAX14979.1 - 1.1e-43 149.1 0.0 3.9e-27 95.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAX14979.1 - 3.9e-40 138.2 32.2 1.9e-25 90.1 15.7 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAX14979.1 - 6.9e-10 38.7 5.0 0.00039 19.9 0.3 4.2 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX14979.1 - 3.2e-07 30.5 0.3 0.19 11.5 0.0 4.8 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAX14979.1 - 0.00032 20.8 0.4 0.023 14.8 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAX14979.1 - 0.0076 16.3 1.7 2.8 8.0 0.2 2.6 2 0 0 2 2 2 2 Dynamin family SbcCD_C PF13558.6 GAX14979.1 - 0.0081 16.4 0.0 3.2 8.0 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAX14979.1 - 0.0082 15.9 0.9 1.2 8.9 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GAX14979.1 - 0.017 14.4 0.3 1.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 GAX14979.1 - 0.035 14.5 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAX14979.1 - 0.035 14.0 0.7 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 GAX14979.1 - 0.14 12.7 0.1 0.53 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAX14979.1 - 0.23 11.2 1.3 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Ala_racemase_N PF01168.20 GAX14980.1 - 7.7e-33 114.0 0.8 1.7e-16 60.5 0.1 3.4 2 1 0 2 2 2 2 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 GAX14980.1 - 4.2e-31 107.3 0.1 9.9e-31 106.1 0.1 1.7 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Proteasom_PSMB PF10508.9 GAX14981.1 - 2.7e-19 69.1 1.8 8.1e-14 51.0 0.0 2.7 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 GAX14981.1 - 0.055 13.9 0.1 2.7 8.4 0.0 3.3 4 0 0 4 4 4 0 HEAT repeats FAD_binding_7 PF03441.14 GAX14982.1 - 3.6e-74 248.6 1.4 5.4e-74 248.0 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAX14982.1 - 2.1e-27 96.1 0.0 3.7e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase ABC_tran PF00005.27 GAX14984.1 - 1.5e-05 25.5 0.0 5.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 GAX14984.1 - 0.00088 19.7 0.1 0.0016 18.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAX14984.1 - 0.001 18.8 0.1 0.0024 17.6 0.0 1.6 1 1 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAX14984.1 - 0.0037 17.3 0.1 0.0073 16.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 GAX14984.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 GAX14984.1 - 0.026 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_15 PF13175.6 GAX14984.1 - 0.069 12.8 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 GAX14984.1 - 0.13 12.1 0.6 0.22 11.3 0.5 1.7 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 GAX14984.1 - 0.14 11.2 0.4 0.31 10.1 0.0 1.8 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 GAX14984.1 - 0.99 9.6 2.9 2.6 8.3 2.7 1.8 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 GAX14985.1 - 1.6e-11 44.9 0.0 7.9e-10 39.4 0.0 2.5 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAX14985.1 - 1.2e-07 31.4 0.0 3.5e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAX14985.1 - 4.2e-07 30.7 0.0 1.7e-06 28.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.6 GAX14985.1 - 0.00055 19.8 0.1 0.0015 18.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX14985.1 - 0.0019 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 GAX14985.1 - 0.066 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.6 GAX14985.1 - 0.096 13.0 0.0 0.97 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 GAX14986.1 - 1.4e-50 172.2 0.0 1.4e-30 106.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14986.1 - 7.2e-25 87.7 0.0 4.2e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAX14986.1 - 1.6e-05 24.4 1.0 0.0096 15.3 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 GAX14986.1 - 0.00046 19.6 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAX14986.1 - 0.005 15.8 0.1 0.0098 14.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAX14986.1 - 0.021 14.8 0.2 0.12 12.2 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pro_isomerase PF00160.21 GAX14987.1 - 1.2e-45 155.6 0.0 1.5e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pyr_redox_2 PF07992.14 GAX14989.1 - 8.6e-52 176.2 0.5 1.1e-51 175.8 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX14989.1 - 7.9e-27 93.7 0.3 1.5e-26 92.8 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX14989.1 - 6.2e-15 55.5 0.1 2.1e-14 53.8 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX14989.1 - 1.9e-05 23.9 0.6 4.7e-05 22.6 0.6 1.7 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAX14989.1 - 7.1e-05 22.2 0.8 9.5e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAX14989.1 - 0.0015 17.7 0.2 0.017 14.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAX14989.1 - 0.0049 15.6 2.3 3.1 6.4 0.2 3.2 2 1 1 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.18 GAX14989.1 - 0.024 14.5 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 GAX14989.1 - 0.5 9.4 8.9 0.23 10.5 2.1 2.9 2 1 1 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 GAX14989.1 - 2.7 8.3 4.9 2.8 8.2 0.9 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GFO_IDH_MocA PF01408.22 GAX14990.1 - 2.7e-16 60.5 0.0 6.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 GAX14990.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 GAX14990.1 - 0.0093 16.4 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX14990.1 - 0.012 15.7 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus STAG PF08514.11 GAX14991.1 - 8.5e-09 35.3 2.5 5.8e-08 32.6 0.1 3.2 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 GAX14991.1 - 3.9e-05 23.5 5.6 0.66 10.4 0.1 6.6 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 GAX14991.1 - 0.00017 21.7 6.2 0.0014 18.6 0.1 4.0 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 GAX14992.1 - 8.3e-18 64.7 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX14992.1 - 1.4e-17 63.8 0.0 2.1e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 GAX14992.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DEAD PF00270.29 GAX14993.1 - 5.9e-37 127.1 0.0 5.2e-34 117.5 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX14993.1 - 3.6e-18 65.9 0.0 1.2e-17 64.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX14993.1 - 6.6e-09 36.0 0.0 2.1e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX14993.1 - 0.021 15.1 2.9 3.3 8.0 1.1 3.5 2 1 0 2 2 2 0 AAA domain DUF2937 PF11157.8 GAX14993.1 - 0.082 12.6 0.2 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) WD40 PF00400.32 GAX14994.1 - 1.4e-48 161.8 21.1 8.3e-09 35.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX14994.1 - 4.6e-12 46.1 0.7 0.00082 19.6 0.0 5.2 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX14994.1 - 0.0025 16.5 7.3 0.087 11.4 0.1 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 GAX14994.1 - 0.0041 15.7 0.1 0.67 8.4 0.3 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 GAX14994.1 - 0.012 15.0 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 GAX14994.1 - 0.017 15.0 0.1 5.3 6.9 0.0 2.9 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAX14994.1 - 0.027 13.4 0.2 3.7 6.4 0.0 3.2 3 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SET PF00856.28 GAX14995.1 - 0.00036 21.0 0.1 0.015 15.7 0.0 2.7 2 2 1 3 3 3 1 SET domain TAT_signal PF10518.9 GAX14997.1 - 0.042 13.7 1.7 0.072 13.0 1.7 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence UCH PF00443.29 GAX14998.1 - 1.2e-37 129.9 0.0 1.5e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAX14998.1 - 1.9e-09 37.7 0.2 4.3e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAX14998.1 - 0.019 14.6 0.1 0.038 13.6 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase MCM6_C PF18263.1 GAX14998.1 - 0.055 13.7 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain MRP-L46 PF11788.8 GAX15000.1 - 2.2e-05 25.2 14.0 3.5e-05 24.5 0.1 3.8 3 1 1 4 4 4 2 39S mitochondrial ribosomal protein L46 HAD_SAK_2 PF18143.1 GAX15000.1 - 0.16 12.3 1.7 0.49 10.7 0.0 2.4 1 1 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins NDUF_B7 PF05676.13 GAX15001.1 - 1.6e-19 69.4 1.6 2e-19 69.1 1.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ATP-synt_D PF01813.17 GAX15002.1 - 4.1e-60 203.0 0.2 5.1e-60 202.7 0.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Brix PF04427.18 GAX15003.1 - 1.2e-25 90.7 0.0 1.5e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 GAX15004.1 - 0.071 11.8 0.0 0.13 11.0 0.0 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain Pkinase PF00069.25 GAX15006.1 - 3e-32 112.1 0.0 4.1e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15006.1 - 2.1e-12 46.9 0.0 3.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UPF0020 PF01170.18 GAX15008.1 - 2e-09 37.5 0.9 3.4e-07 30.2 0.9 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 GAX15008.1 - 0.00013 21.7 0.0 0.00034 20.3 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.18 GAX15008.1 - 0.0011 18.7 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 DNA methylase DUF1118 PF06549.12 GAX15009.1 - 0.00042 20.6 6.6 0.00042 20.6 6.6 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1118) Prenylcys_lyase PF07156.14 GAX15010.1 - 4.8e-30 104.9 0.0 1.8e-15 56.9 0.0 2.6 2 1 0 2 2 2 2 Prenylcysteine lyase DAO PF01266.24 GAX15010.1 - 4.4e-06 26.5 0.1 1.6e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX15010.1 - 0.00052 20.2 0.0 0.0014 18.8 0.0 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAX15010.1 - 0.014 15.4 0.1 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GAX15010.1 - 0.031 13.6 0.1 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 GAX15010.1 - 0.082 11.7 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 GAX15010.1 - 0.09 12.0 0.0 0.4 9.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PH PF00169.29 GAX15011.1 - 1.3e-11 44.9 0.1 2.8e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAX15011.1 - 0.0014 18.9 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAX15011.1 - 0.0037 17.7 1.6 0.11 12.9 1.6 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Ribosomal_L32p PF01783.23 GAX15011.1 - 0.24 11.7 1.3 0.73 10.1 1.3 1.9 1 0 0 1 1 1 0 Ribosomal L32p protein family LRR_8 PF13855.6 GAX15012.1 - 0.00094 18.9 0.1 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GAX15012.1 - 0.0019 18.6 0.2 0.0044 17.4 0.2 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) DS PF01916.17 GAX15013.1 - 1.3e-124 415.2 0.0 1.5e-124 414.9 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 GAX15013.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Peptidase_M16_M PF16187.5 GAX15014.1 - 2.6e-41 141.8 0.0 4e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX15014.1 - 2.3e-31 108.8 0.1 3.4e-30 105.0 0.1 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX15014.1 - 5.2e-23 82.0 0.0 1.2e-15 58.0 0.0 3.3 2 1 1 3 3 3 2 Peptidase M16 inactive domain Cse1 PF08506.10 GAX15015.1 - 9.5e-123 409.7 0.0 3.3e-122 407.9 0.1 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 GAX15015.1 - 2.9e-109 365.5 1.7 4.2e-109 365.0 0.5 1.9 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 GAX15015.1 - 4.1e-12 45.8 0.0 1.9e-11 43.7 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAX15015.1 - 7.2e-05 22.9 0.3 0.0027 17.8 0.1 3.8 3 1 1 4 4 4 1 Exportin 1-like protein EcsC PF12787.7 GAX15015.1 - 0.098 12.3 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 EcsC protein family TAF6_C PF07571.13 GAX15015.1 - 0.21 11.9 0.5 19 5.6 0.1 3.8 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Choline_transpo PF04515.12 GAX15016.1 - 1.1e-68 231.8 25.4 1.1e-68 231.8 25.4 2.8 1 1 1 2 2 2 2 Plasma-membrane choline transporter DUF3215 PF11503.8 GAX15016.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) SAC3_GANP PF03399.16 GAX15017.1 - 3.1e-71 240.1 0.2 6.2e-45 153.8 0.1 2.6 2 0 0 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAX15017.1 - 7.8e-06 25.9 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PAM2 PF07145.15 GAX15017.1 - 0.0066 16.1 0.5 0.022 14.4 0.5 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF179 PF02622.15 GAX15018.1 - 5.8e-17 62.1 0.0 1.4e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 TFIID_30kDa PF03540.13 GAX15019.1 - 1.8e-06 27.8 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 GAX15019.1 - 0.0037 17.1 7.8 0.0037 17.1 7.8 2.4 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Fip1 PF05182.13 GAX15020.1 - 1.4e-16 59.7 0.5 2.8e-16 58.8 0.5 1.6 1 0 0 1 1 1 1 Fip1 motif PLAC8 PF04749.17 GAX15021.1 - 2.8e-11 44.3 13.5 2.8e-11 44.3 13.5 2.0 2 0 0 2 2 2 1 PLAC8 family EXS PF03124.14 GAX15022.1 - 2.6e-53 181.5 6.4 2.6e-53 181.5 6.4 2.0 2 1 0 2 2 2 1 EXS family ATPgrasp_Ter PF15632.6 GAX15023.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ArfGap PF01412.18 GAX15024.1 - 6.6e-27 93.9 0.1 9.6e-27 93.4 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pkinase PF00069.25 GAX15025.1 - 1.4e-46 159.0 0.0 1.8e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15025.1 - 9.1e-23 80.9 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX15025.1 - 0.00017 21.6 0.1 0.00034 20.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX15025.1 - 0.042 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 GAX15025.1 - 0.042 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GAX15025.1 - 0.093 11.5 0.0 0.17 10.6 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 GAX15025.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PHD PF00628.29 GAX15026.1 - 1.3e-09 37.8 8.8 3.7e-09 36.4 8.8 1.8 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 GAX15026.1 - 0.0068 16.0 5.8 0.0069 16.0 3.8 2.0 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain DDT PF02791.17 GAX15026.1 - 0.011 16.0 0.1 0.026 14.8 0.1 1.6 1 0 0 1 1 1 0 DDT domain Prok-RING_1 PF14446.6 GAX15026.1 - 0.022 14.7 6.1 0.053 13.5 6.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Peptidase_A17 PF05380.13 GAX15026.1 - 0.035 14.1 0.2 0.097 12.7 0.2 1.7 1 0 0 1 1 1 0 Pao retrotransposon peptidase PHD_2 PF13831.6 GAX15026.1 - 0.055 13.0 2.4 0.11 12.1 2.4 1.5 1 0 0 1 1 1 0 PHD-finger RRM_3 PF08777.11 GAX15027.1 - 0.0037 17.3 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 GAX15027.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3149 PF11346.8 GAX15027.1 - 0.082 12.5 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) UPF0172 PF03665.13 GAX15028.1 - 4.6e-22 79.0 0.0 5.4e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 GAX15028.1 - 0.0003 20.8 0.1 0.0031 17.5 0.1 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DSPc PF00782.20 GAX15029.1 - 2.7e-15 56.3 0.0 4.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX15029.1 - 0.00057 19.5 0.0 0.0008 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAX15029.1 - 0.022 14.9 0.0 0.066 13.3 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate BOP1NT PF08145.12 GAX15030.1 - 3.6e-85 286.0 0.7 5e-85 285.6 0.7 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 GAX15030.1 - 5.8e-21 74.4 8.4 0.00018 22.2 0.0 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15030.1 - 1.5e-07 31.6 0.0 0.00072 19.8 0.0 4.3 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX15030.1 - 0.2 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Spt5-NGN PF03439.13 GAX15032.1 - 3.2e-17 62.2 0.0 6.8e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 GAX15032.1 - 2.6e-13 49.4 28.4 3.1e-05 23.8 1.4 8.1 8 0 0 8 8 8 4 KOW motif Spt5_N PF11942.8 GAX15032.1 - 0.00094 20.1 10.4 0.00094 20.1 10.4 4.5 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 GAX15032.1 - 0.0093 16.2 1.4 11 6.4 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3912) Pertussis_S1 PF02917.14 GAX15032.1 - 0.093 12.5 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 ProQ_C PF17516.2 GAX15032.1 - 1.9 8.0 6.7 1.1 8.7 0.6 3.5 4 0 0 4 4 4 0 ProQ C-terminal domain rRNA_proc-arch PF13234.6 GAX15034.1 - 3e-55 188.1 0.2 5.3e-55 187.2 0.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 GAX15034.1 - 1.2e-18 67.4 0.0 3.8e-18 65.7 0.0 2.0 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 GAX15034.1 - 8.9e-18 64.7 0.2 8.2e-17 61.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX15034.1 - 9.1e-08 32.4 0.0 2.2e-06 28.0 0.0 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 GAX15034.1 - 0.001 19.0 0.1 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 GAX15034.1 - 0.091 12.5 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3736 PF12540.8 GAX15034.1 - 0.1 12.7 0.4 0.26 11.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) Cytochrom_C_2 PF01322.20 GAX15034.1 - 0.2 12.6 2.2 0.55 11.1 0.5 2.6 2 0 0 2 2 2 0 Cytochrome C' AAA PF00004.29 GAX15035.1 - 6.5e-34 117.2 0.0 6.9e-21 75.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX15035.1 - 5.9e-12 46.3 0.3 0.0026 18.1 0.3 4.7 4 1 1 5 5 5 2 AAA ATPase domain AAA_5 PF07728.14 GAX15035.1 - 5.1e-06 26.5 0.2 0.16 12.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 GAX15035.1 - 1.2e-05 24.9 0.4 0.27 11.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 GAX15035.1 - 3.7e-05 23.7 3.6 0.19 11.6 0.1 4.5 3 1 0 3 3 3 1 NACHT domain IstB_IS21 PF01695.17 GAX15035.1 - 8.7e-05 22.3 0.1 0.47 10.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 GAX15035.1 - 0.00011 22.5 4.9 0.14 12.4 0.0 4.3 3 1 2 5 5 4 2 AAA domain Sigma54_activat PF00158.26 GAX15035.1 - 0.00073 19.3 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 GAX15035.1 - 0.0015 18.0 0.2 0.73 9.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAX15035.1 - 0.0017 17.8 0.0 0.49 9.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GAX15035.1 - 0.0027 17.5 0.0 0.53 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAX15035.1 - 0.0028 18.0 1.1 3.1 8.1 0.3 3.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAX15035.1 - 0.0064 15.7 0.2 0.15 11.2 0.1 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 GAX15035.1 - 0.0071 16.9 0.1 1.4 9.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 GAX15035.1 - 0.012 15.1 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 GAX15035.1 - 0.013 15.4 0.3 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 GAX15035.1 - 0.016 15.4 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAX15035.1 - 0.027 15.0 0.3 2.4 8.7 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Bac_DnaA PF00308.18 GAX15035.1 - 0.029 14.2 0.0 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein T2SSE PF00437.20 GAX15035.1 - 0.034 13.2 0.2 1 8.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 GAX15035.1 - 0.038 14.4 0.0 6.4 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 GAX15035.1 - 0.038 13.9 0.3 1.4 8.8 0.0 3.1 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 GAX15035.1 - 0.042 13.6 0.4 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 GAX15035.1 - 0.044 13.5 0.3 0.72 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAX15035.1 - 0.065 12.7 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 GAX15035.1 - 0.081 12.9 0.1 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 GAX15035.1 - 0.15 11.3 0.5 19 4.5 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 GAX15035.1 - 0.22 12.0 0.0 27 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX15035.1 - 0.22 11.1 1.7 26 4.3 0.1 3.0 3 0 0 3 3 3 0 AAA domain Adaptin_N PF01602.20 GAX15036.1 - 4e-83 279.7 0.0 5.6e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAX15036.1 - 8e-43 146.3 0.0 2.1e-40 138.4 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 GAX15036.1 - 1.4e-10 41.2 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 GAX15036.1 - 1.5e-09 38.1 1.2 0.00095 19.5 0.0 4.2 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.22 GAX15036.1 - 5.1e-05 23.2 4.0 0.27 11.6 0.1 4.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 GAX15036.1 - 0.058 13.9 3.4 3.8 8.1 0.0 4.9 4 1 1 5 5 5 0 HEAT-like repeat Lipase_GDSL_2 PF13472.6 GAX15037.1 - 9.5e-07 29.4 0.2 0.1 13.0 0.0 3.4 2 1 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX15037.1 - 0.081 12.9 0.0 1.4 8.8 0.0 2.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase OmpH PF03938.14 GAX15037.1 - 1.6 9.0 3.4 3.2 8.1 3.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Proteasome PF00227.26 GAX15038.1 - 4.6e-35 120.8 0.1 5.4e-35 120.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit GHMP_kinases_N PF00288.26 GAX15038.1 - 0.19 12.0 2.2 1.5 9.1 0.6 2.8 1 1 1 2 2 2 0 GHMP kinases N terminal domain LRR_6 PF13516.6 GAX15040.1 - 4.1e-24 82.5 19.2 2.5e-05 24.0 0.2 9.9 10 0 0 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.33 GAX15040.1 - 1.1e-07 31.4 2.8 1.9 9.4 0.1 6.6 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.7 GAX15040.1 - 0.002 18.5 8.1 0.096 13.1 2.2 4.7 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX15040.1 - 0.013 15.3 3.5 19 5.1 0.0 4.2 4 0 0 4 4 4 0 Leucine rich repeat Dynamin_N PF00350.23 GAX15041.1 - 3.9e-10 40.0 0.0 7.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAX15041.1 - 8.7e-09 35.5 0.1 2.8e-08 33.8 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX15041.1 - 0.0019 17.8 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GAX15041.1 - 0.0058 16.8 0.1 0.042 14.1 0.0 2.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 GAX15041.1 - 0.026 13.8 1.6 0.028 13.7 0.1 1.9 2 1 0 2 2 2 0 Septin MHC_II_beta PF00969.19 GAX15041.1 - 0.036 14.2 0.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain FeoB_N PF02421.18 GAX15041.1 - 0.047 13.2 0.1 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.6 GAX15041.1 - 0.081 13.4 3.7 0.55 10.7 3.7 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAX15041.1 - 0.084 12.9 0.0 0.31 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX15041.1 - 0.11 12.7 0.1 0.27 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 GAX15041.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.6 GAX15041.1 - 0.15 12.4 0.1 0.7 10.3 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 GAX15041.1 - 0.16 12.5 1.1 0.97 9.9 1.0 2.4 1 1 0 1 1 1 0 ABC transporter HNH_3 PF13392.6 GAX15042.1 - 1e-15 57.2 0.0 7.5e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 HNH endonuclease Nudc_N PF14050.6 GAX15044.1 - 2.8e-19 68.8 0.1 4.6e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 GAX15044.1 - 1.3e-13 51.8 0.1 3.2e-13 50.5 0.1 1.7 2 0 0 2 2 2 1 CS domain CIA30 PF08547.12 GAX15046.1 - 4.7e-07 30.0 0.0 1.5e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Adaptin_binding PF10199.9 GAX15047.1 - 1.1e-07 32.5 7.7 2.7e-07 31.2 7.7 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 FeoB_Cyto PF17910.1 GAX15049.1 - 0.052 14.1 1.1 0.052 14.1 1.1 2.1 2 0 0 2 2 2 0 FeoB cytosolic helical domain TssC PF17541.2 GAX15049.1 - 1.1 8.0 6.1 0.062 12.1 0.8 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB Sugar_tr PF00083.24 GAX15050.1 - 1.2e-38 133.2 17.3 1.6e-38 132.7 17.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX15050.1 - 6.5e-30 104.2 28.5 9.8e-30 103.7 28.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.6 GAX15050.1 - 7.9 6.8 9.4 3.5 8.0 0.2 3.4 3 0 0 3 3 3 0 Stage V sporulation protein AB Pyr_redox_2 PF07992.14 GAX15051.1 - 2e-34 119.2 0.0 2.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX15051.1 - 2.9e-23 82.6 0.0 3.5e-19 69.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.24 GAX15051.1 - 3.2e-12 46.5 0.0 6.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin FAD_binding_2 PF00890.24 GAX15051.1 - 2e-09 37.1 9.8 0.00027 20.2 1.2 3.8 3 1 0 4 4 4 3 FAD binding domain FAD_oxidored PF12831.7 GAX15051.1 - 4.4e-07 29.6 4.4 0.00018 21.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX15051.1 - 7e-07 29.7 0.4 2.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX15051.1 - 1.1e-06 27.6 3.8 0.0056 15.4 0.3 4.0 4 0 0 4 4 4 2 HI0933-like protein GIDA PF01134.22 GAX15051.1 - 1.6e-06 27.5 2.7 0.027 13.5 0.0 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAX15051.1 - 3.3e-05 23.3 2.2 0.075 12.3 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 GAX15051.1 - 4.3e-05 22.8 0.7 0.0033 16.6 0.0 2.4 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAX15051.1 - 0.00013 22.1 1.3 0.019 15.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX15051.1 - 0.00022 20.6 2.6 0.0098 15.1 0.3 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAX15051.1 - 0.00084 19.0 3.5 0.4 10.2 0.3 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX15051.1 - 0.002 17.2 1.3 0.57 9.2 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GAX15051.1 - 0.0096 15.2 1.1 1.9 7.7 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 GAX15051.1 - 0.012 16.1 0.0 0.058 13.8 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 GAX15051.1 - 0.24 10.2 2.0 1.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HATPase_c PF02518.26 GAX15052.1 - 1.4e-12 48.1 0.0 2.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX15052.1 - 4.5e-10 39.5 0.0 8.5e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Topo-VIb_trans PF09239.11 GAX15052.1 - 0.021 14.7 0.0 0.81 9.5 0.0 2.4 2 0 0 2 2 2 0 Topoisomerase VI B subunit, transducer HATPase_c_5 PF14501.6 GAX15052.1 - 0.023 14.6 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 GHKL domain Aldo_ket_red PF00248.21 GAX15053.1 - 9.9e-47 159.5 0.0 1.3e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FAD-SLDH PF12318.8 GAX15053.1 - 0.078 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase eIF2_C PF09173.11 GAX15053.1 - 0.095 13.0 0.1 0.32 11.3 0.1 1.9 1 0 0 1 1 1 0 Initiation factor eIF2 gamma, C terminal KorB PF08535.10 GAX15053.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 KorB domain AAA PF00004.29 GAX15054.1 - 1.2e-15 58.1 0.0 1.2e-06 29.0 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX15054.1 - 5.6e-06 26.4 0.0 3e-05 24.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX15054.1 - 6.3e-05 23.4 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GAX15054.1 - 0.00061 20.3 0.0 0.0023 18.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAX15054.1 - 0.0043 17.3 0.0 0.021 15.0 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 GAX15054.1 - 0.0047 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX15054.1 - 0.005 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAX15054.1 - 0.012 15.4 0.1 0.046 13.5 0.0 2.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 GAX15054.1 - 0.019 14.8 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAX15054.1 - 0.048 13.6 0.2 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 GAX15054.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 GAX15054.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAX15054.1 - 0.057 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 GAX15054.1 - 0.066 13.7 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 GAX15054.1 - 0.071 12.8 0.1 0.19 11.4 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 GAX15054.1 - 0.091 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 GAX15054.1 - 0.097 13.2 0.2 0.67 10.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 GAX15054.1 - 0.097 12.4 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GAX15054.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 GAX15054.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 GAX15054.1 - 0.13 12.6 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Arf PF00025.21 GAX15055.1 - 2.1e-63 212.9 0.0 2.4e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAX15055.1 - 3.3e-10 39.7 0.0 4.2e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAX15055.1 - 3.4e-10 39.6 0.1 1.7e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAX15055.1 - 4.7e-09 36.5 0.0 9.2e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX15055.1 - 1.9e-08 34.1 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAX15055.1 - 1.1e-07 31.9 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX15055.1 - 9.7e-06 25.1 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Antibiotic_NAT PF02522.14 GAX15055.1 - 0.0098 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase PduV-EutP PF10662.9 GAX15055.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 GAX15055.1 - 0.068 13.1 0.1 6.8 6.6 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 GAX15055.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 GAX15056.1 - 2.2e-46 158.3 0.0 3.3e-33 115.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15056.1 - 5.4e-20 71.8 1.6 1.7e-10 40.6 0.0 4.0 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 GAX15056.1 - 3e-13 50.1 0.0 7.7e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 RWD domain Renin_r PF07850.14 GAX15058.1 - 1.3e-05 25.7 0.0 3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Renin receptor-like protein MRAP PF15183.6 GAX15058.1 - 0.11 12.5 0.4 0.22 11.5 0.4 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family EAGR_box PF16713.5 GAX15058.1 - 2.4 7.9 10.0 5.6 6.7 10.0 1.6 1 1 0 1 1 1 0 Enriched in aromatic and glycine Residues box Dynamin_M PF01031.20 GAX15059.1 - 6.5e-97 324.2 0.0 1e-96 323.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GAX15059.1 - 4.3e-53 179.8 0.0 8.5e-53 178.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GAX15059.1 - 3.3e-30 104.1 0.3 7.1e-30 103.0 0.3 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAX15059.1 - 0.00025 21.1 0.1 0.0016 18.5 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAX15059.1 - 0.041 13.2 0.4 8.1 5.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family HSP90 PF00183.18 GAX15060.1 - 1.2e-231 770.1 24.2 1.6e-231 769.7 24.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAX15060.1 - 7.6e-15 55.4 0.0 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX15060.1 - 2.3e-10 40.4 0.1 6.3e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PTN_MK_N PF05196.13 GAX15061.1 - 0.18 12.0 0.8 0.48 10.7 0.2 1.9 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain Ndc80_HEC PF03801.13 GAX15062.1 - 1.4e-37 128.7 0.0 3.7e-37 127.3 0.0 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family zf-C4H2 PF10146.9 GAX15062.1 - 4.5e-05 23.9 27.5 0.00018 21.9 8.0 2.5 2 0 0 2 2 2 2 Zinc finger-containing protein IFT57 PF10498.9 GAX15062.1 - 5.4e-05 22.3 6.7 5.4e-05 22.3 6.7 3.2 2 1 0 3 3 3 2 Intra-flagellar transport protein 57 KASH_CCD PF14662.6 GAX15062.1 - 0.00016 21.5 14.6 0.00016 21.5 14.6 2.9 2 1 0 2 2 1 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 GAX15062.1 - 0.00023 20.2 43.9 0.00024 20.1 15.8 3.4 1 1 2 3 3 3 2 Spc7 kinetochore protein AAA_13 PF13166.6 GAX15062.1 - 0.00026 19.8 31.0 0.0042 15.8 11.5 2.3 1 1 1 2 2 2 2 AAA domain CALCOCO1 PF07888.11 GAX15062.1 - 0.0011 17.9 14.9 0.0011 17.9 14.9 2.2 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like BLOC1_2 PF10046.9 GAX15062.1 - 0.014 15.7 28.3 0.037 14.3 4.0 5.1 2 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 GAX15062.1 - 0.016 15.2 18.4 0.36 10.8 7.3 2.8 2 1 0 2 2 2 0 Laminin Domain II MAD PF05557.13 GAX15062.1 - 0.032 12.6 36.9 0.098 11.0 14.3 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 GAX15062.1 - 0.051 14.0 30.2 0.22 11.9 11.6 2.5 2 0 0 2 2 2 0 Fez1 KMP11 PF03037.16 GAX15062.1 - 0.057 14.2 16.8 0.22 12.3 4.8 3.6 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 Fib_alpha PF08702.10 GAX15062.1 - 0.068 13.4 31.8 0.57 10.4 8.1 3.8 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 GAX15062.1 - 0.089 11.9 24.9 0.15 11.2 9.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 GAX15062.1 - 0.13 11.6 25.7 1.1 8.5 8.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 GAX15062.1 - 0.31 11.7 0.1 0.31 11.7 0.1 6.2 2 2 2 5 5 5 0 SlyX DASH_Dam1 PF08653.10 GAX15062.1 - 0.39 10.6 3.5 1 9.2 0.6 3.1 1 1 1 2 2 2 0 DASH complex subunit Dam1 Lebercilin PF15619.6 GAX15062.1 - 0.4 10.3 41.9 0.38 10.4 15.4 3.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DASH_Duo1 PF08651.10 GAX15062.1 - 0.6 9.9 11.3 5.2 6.9 0.8 4.1 3 1 0 3 3 3 0 DASH complex subunit Duo1 Filament PF00038.21 GAX15062.1 - 0.79 9.3 37.4 0.039 13.5 10.9 3.3 2 1 1 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 GAX15062.1 - 1.8 8.6 23.9 0.39 10.8 4.9 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Nup88 PF10168.9 GAX15062.1 - 2.2 6.0 21.8 1.4 6.7 9.1 2.3 2 0 0 2 2 2 0 Nuclear pore component FTA4 PF13093.6 GAX15062.1 - 2.8 7.8 22.1 0.064 13.1 5.0 2.6 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MCPsignal PF00015.21 GAX15062.1 - 2.9 7.7 12.7 8.8 6.1 0.7 3.2 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RasGAP_C PF03836.15 GAX15062.1 - 5.9 7.0 17.6 3.3 7.9 9.2 3.3 2 1 1 3 3 3 0 RasGAP C-terminus LXG PF04740.12 GAX15062.1 - 6.6 6.4 23.1 0.99 9.1 0.5 3.6 2 1 1 3 3 3 0 LXG domain of WXG superfamily DUF3450 PF11932.8 GAX15062.1 - 7.2 5.8 31.2 0.27 10.5 9.7 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 GAX15062.1 - 9.3 6.6 10.8 9.6 6.6 0.5 3.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MAM33 PF02330.16 GAX15063.1 - 3.1e-35 122.1 1.8 4.2e-35 121.6 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Inositol_P PF00459.25 GAX15064.1 - 1.2e-52 179.1 0.0 1.5e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Pho88 PF10032.9 GAX15065.1 - 2e-30 105.4 0.6 4.5e-30 104.3 0.6 1.6 1 1 0 1 1 1 1 Phosphate transport (Pho88) SID-1_RNA_chan PF13965.6 GAX15065.1 - 0.12 10.8 0.6 0.25 9.7 0.1 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4820 PF16091.5 GAX15065.1 - 6.9 6.0 8.6 12 5.1 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Coilin_N PF15862.5 GAX15065.1 - 7.5 6.4 9.9 0.51 10.1 4.7 1.6 2 0 0 2 2 2 0 Coilin N-terminus Pyridox_oxase_2 PF12766.7 GAX15066.1 - 3.4e-27 95.0 0.1 4.6e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 GAX15066.1 - 0.00011 22.4 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNA_pol_Rpb1_1 PF04997.12 GAX15067.1 - 4.1e-89 299.0 0.0 7.1e-89 298.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAX15067.1 - 4.4e-83 278.8 0.5 6.3e-83 278.3 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAX15067.1 - 3.8e-73 245.2 0.1 6.2e-73 244.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAX15067.1 - 1.1e-31 109.9 0.0 7.2e-31 107.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAX15067.1 - 3e-27 94.7 0.0 8.3e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-tcix PF14952.6 GAX15067.1 - 0.0031 17.1 3.5 0.009 15.6 3.5 1.7 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Romo1 PF10247.9 GAX15068.1 - 9.6e-05 22.7 2.3 0.034 14.5 0.1 2.2 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 GAX15068.1 - 0.038 14.4 1.5 0.056 13.8 1.5 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family F-box PF00646.33 GAX15069.1 - 0.03 14.2 0.6 0.08 12.8 0.6 1.7 1 0 0 1 1 1 0 F-box domain RCC1 PF00415.18 GAX15070.1 - 1.6e-48 163.1 22.4 1.6e-12 47.8 0.3 8.7 8 2 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX15070.1 - 2.6e-37 125.9 31.2 5.7e-11 41.9 0.2 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat ChaC PF04752.12 GAX15070.1 - 2e-31 109.4 0.0 3.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 GAX15070.1 - 1.4e-05 25.7 0.0 3.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Kelch_4 PF13418.6 GAX15070.1 - 0.24 11.4 1.7 2.1e+02 2.0 0.1 4.9 5 0 0 5 5 5 0 Galactose oxidase, central domain IMS PF00817.20 GAX15071.1 - 7.3e-32 110.4 0.0 4.9e-31 107.8 0.0 2.4 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 GAX15071.1 - 4.9e-11 43.4 0.0 1e-10 42.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAX15071.1 - 0.0028 17.9 0.0 0.0066 16.7 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif MitMem_reg PF13012.6 GAX15072.1 - 1.9e-30 105.6 0.5 3.4e-30 104.7 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAX15072.1 - 1.2e-28 99.5 0.0 1.9e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GlcNAc PF11397.8 GAX15073.1 - 1.9e-52 178.9 3.0 1.6e-41 142.9 1.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) DUF755 PF05501.11 GAX15073.1 - 0.062 13.6 1.3 0.12 12.6 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF5454 PF17535.2 GAX15073.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5454) IF-2B PF01008.17 GAX15074.1 - 6.8e-39 133.8 0.1 9.8e-39 133.2 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family adh_short PF00106.25 GAX15076.1 - 1.3e-44 152.1 0.1 1.8e-44 151.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX15076.1 - 1.6e-25 90.0 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX15076.1 - 7.8e-09 35.7 0.0 1.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX15076.1 - 0.0047 16.1 0.2 0.0073 15.5 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 GAX15076.1 - 0.053 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LDcluster4 PF18306.1 GAX15076.1 - 0.095 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster4 family Epimerase PF01370.21 GAX15076.1 - 0.12 11.8 0.2 0.46 9.9 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 GAX15076.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sel1 PF08238.12 GAX15079.1 - 1.5e-23 82.7 12.6 1.9e-08 34.7 0.8 5.4 5 0 0 5 5 5 5 Sel1 repeat Polyketide_cyc2 PF10604.9 GAX15080.1 - 2.3e-09 37.6 0.1 3.2e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX15080.1 - 1.1e-05 25.6 0.9 1.9e-05 24.8 0.2 1.7 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport HA2 PF04408.23 GAX15081.1 - 3.2e-19 69.2 0.0 6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAX15081.1 - 5.8e-11 42.7 0.0 1.4e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX15081.1 - 1.1e-07 31.8 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 GAX15081.1 - 6.4e-07 29.7 0.0 1.7e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 GAX15081.1 - 2.3e-05 24.7 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX15081.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX15081.1 - 0.062 13.8 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAX15081.1 - 0.097 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3418 PF11898.8 GAX15082.1 - 0.014 14.1 0.1 0.017 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Pkinase PF00069.25 GAX15083.1 - 1e-54 185.7 0.0 1.3e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15083.1 - 8.5e-42 143.2 0.0 1.4e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX15083.1 - 0.0008 18.3 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAX15083.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAX15083.1 - 0.0021 17.1 0.0 0.007 15.4 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAX15083.1 - 0.052 13.5 0.2 0.083 12.8 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GCIP PF13324.6 GAX15083.1 - 0.36 10.4 1.5 0.74 9.4 1.5 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting tRNA-synt_2d PF01409.20 GAX15084.1 - 2.7e-87 292.3 0.0 3.7e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 GAX15084.1 - 6.7e-16 58.3 1.2 2.1e-15 56.7 0.7 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 GAX15084.1 - 2.2e-09 36.9 0.0 6.7e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 GAX15084.1 - 8.2e-07 28.7 0.0 0.00013 21.5 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 GAX15084.1 - 5.6e-05 22.4 0.0 0.00014 21.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 GAX15084.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) IlvC PF01450.19 GAX15084.1 - 0.015 15.6 0.2 0.035 14.4 0.2 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain HTH_30 PF13556.6 GAX15084.1 - 0.14 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain PheRS_DBD2 PF18554.1 GAX15084.1 - 3.3 7.8 7.3 5.6 7.0 4.9 2.6 2 1 0 2 2 2 0 PheRS DNA binding domain 2 Myb_DNA-binding PF00249.31 GAX15085.1 - 0.00079 19.6 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX15085.1 - 0.025 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Fer2 PF00111.27 GAX15086.1 - 3.7e-10 39.6 0.3 5.2e-10 39.1 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Thioredoxin_8 PF13905.6 GAX15086.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Aldedh PF00171.22 GAX15088.1 - 7.3e-07 28.1 0.2 1e-06 27.5 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family cpYpsA PF12694.7 GAX15088.1 - 0.054 13.3 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family FTCD_C PF04961.12 GAX15089.1 - 3.3e-35 121.5 2.3 4.1e-35 121.2 2.3 1.1 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase SAP130_C PF16014.5 GAX15091.1 - 0.82 8.7 9.7 0.063 12.4 4.9 1.5 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus EF-hand_8 PF13833.6 GAX15092.1 - 8.9e-06 25.5 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 GAX15092.1 - 0.02 15.4 0.1 0.055 13.9 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair CorA PF01544.18 GAX15092.1 - 0.22 10.8 10.5 0.44 9.8 7.6 2.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein APCDDC PF14921.6 GAX15092.1 - 0.23 10.9 0.3 8.4 5.8 0.1 2.1 2 0 0 2 2 2 0 Adenomatosis polyposis coli down-regulated 1 GSH_synth_ATP PF03917.17 GAX15093.1 - 2.5e-110 368.8 0.0 3.1e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 GAX15093.1 - 1.7e-28 99.1 0.0 2.9e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Mito_carr PF00153.27 GAX15094.1 - 2.2e-67 223.0 4.1 4.4e-24 84.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX15094.1 - 0.057 12.6 3.5 5.8 6.0 0.0 3.2 2 1 1 3 3 3 0 Gammaproteobacterial serine protease LapA_dom PF06305.11 GAX15094.1 - 0.11 12.4 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain 2OG-FeII_Oxy_2 PF13532.6 GAX15095.1 - 1e-28 100.9 2.8 4.2e-13 49.9 0.6 2.8 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily DZR PF12773.7 GAX15096.1 - 7.5e-07 29.1 2.6 2.2e-06 27.6 2.6 1.8 1 1 0 1 1 1 1 Double zinc ribbon zf-dskA_traR PF01258.17 GAX15096.1 - 8.5 6.4 10.8 55 3.8 5.4 3.3 2 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger FANCL_C PF11793.8 GAX15097.1 - 0.2 11.9 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain XPC-binding PF09280.11 GAX15098.1 - 6e-21 73.9 15.4 6e-21 73.9 15.4 3.3 3 1 0 3 3 2 1 XPC-binding domain UBA PF00627.31 GAX15098.1 - 2.8e-19 68.6 6.9 3.9e-09 36.2 0.0 3.3 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 GAX15098.1 - 1.2e-18 66.6 0.3 2.1e-18 65.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX15098.1 - 1.8e-07 30.9 0.3 3e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAX15098.1 - 0.00024 21.6 0.0 0.00054 20.5 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain WIYLD PF10440.9 GAX15098.1 - 0.00057 19.6 0.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-binding WIYLD domain Ubiquitin_4 PF18036.1 GAX15098.1 - 0.00095 19.2 0.5 0.036 14.1 0.3 2.3 1 1 1 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX15098.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ThiS PF02597.20 GAX15098.1 - 0.12 13.0 0.5 9.8 6.9 0.1 2.6 2 0 0 2 2 2 0 ThiS family TFIIA PF03153.13 GAX15098.1 - 0.12 12.3 11.7 0.16 11.9 11.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UBA_3 PF09288.10 GAX15098.1 - 0.14 12.0 0.0 19 5.1 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain CUE PF02845.16 GAX15098.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.3 5 0 0 5 5 4 0 CUE domain FliG_N PF14842.6 GAX15098.1 - 0.42 11.2 5.5 0.43 11.1 0.1 3.0 2 1 1 3 3 3 0 FliG N-terminal domain DUF3617 PF12276.8 GAX15098.1 - 7.7 6.9 10.2 4 7.8 0.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3617) PWI PF01480.17 GAX15099.1 - 3.9e-21 75.2 0.1 6.2e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 PWI domain CCDC53 PF10152.9 GAX15099.1 - 6.9 7.1 8.3 0.42 11.0 1.7 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Methyltransf_25 PF13649.6 GAX15101.1 - 4.7e-06 27.2 0.0 1.3e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GAX15101.1 - 7.2e-06 25.8 0.1 0.00057 19.6 0.0 2.8 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 GAX15101.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX15101.1 - 0.00067 20.3 0.0 0.0019 18.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX15101.1 - 0.0023 17.8 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX15101.1 - 0.0085 16.8 0.0 0.026 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 GAX15101.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 GAX15101.1 - 0.034 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 N6_Mtase PF02384.16 GAX15101.1 - 0.056 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 N-6 DNA Methylase TehB PF03848.14 GAX15101.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Prefoldin PF02996.17 GAX15102.1 - 1.6e-24 86.1 1.0 2e-24 85.8 1.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Rad9 PF04139.13 GAX15103.1 - 2.4e-23 82.9 0.1 3.2e-23 82.5 0.1 1.2 1 0 0 1 1 1 1 Rad9 DUF3666 PF12408.8 GAX15103.1 - 0.23 10.7 1.4 3.2 7.1 0.2 2.4 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase CAP PF00188.26 GAX15104.1 - 1.1e-07 32.7 0.0 1.8e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SAC3_GANP PF03399.16 GAX15106.1 - 2.8e-20 72.9 0.9 8.3e-11 41.8 0.1 2.1 2 0 0 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAX15106.1 - 7.2e-05 22.8 0.1 0.00012 22.1 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RPM2 PF08579.11 GAX15106.1 - 0.053 13.9 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Sec62 PF03839.16 GAX15107.1 - 2.8e-29 102.2 3.8 2.8e-29 102.2 3.8 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 PseudoU_synth_2 PF00849.22 GAX15108.1 - 1.6e-20 73.8 0.0 3.3e-20 72.8 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase RPN1_RPN2_N PF17781.1 GAX15109.1 - 5.9e-107 357.6 0.2 1e-106 356.9 0.2 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 GAX15109.1 - 1.1e-30 105.4 0.2 2.3e-30 104.4 0.2 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 GAX15109.1 - 5.1e-23 80.3 25.9 3.3e-05 24.1 0.2 9.0 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAX15109.1 - 1.6e-06 28.4 1.5 0.36 11.3 0.0 4.9 3 1 1 4 4 4 2 HEAT repeats TPR_15 PF13429.6 GAX15109.1 - 0.00059 19.1 0.1 0.0015 17.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 GAX15109.1 - 0.038 14.5 0.5 23 5.7 0.1 3.7 3 1 1 4 4 4 0 HEAT-like repeat GLTSCR1 PF15249.6 GAX15109.1 - 0.061 13.8 0.1 0.21 12.0 0.1 1.9 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein Sterol_MT_C PF08498.10 GAX15109.1 - 0.15 12.3 0.1 0.56 10.6 0.1 2.0 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal CIA30 PF08547.12 GAX15110.1 - 3.7e-22 79.1 0.0 6e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) zf-MYND PF01753.18 GAX15111.1 - 2.7e-07 30.5 19.0 2.7e-07 30.5 19.0 2.5 3 0 0 3 3 3 1 MYND finger TMEM151 PF14857.6 GAX15111.1 - 0.0017 17.4 0.2 0.0027 16.7 0.2 1.2 1 0 0 1 1 1 1 TMEM151 family zf-MYND PF01753.18 GAX15112.1 - 4.6e-06 26.6 13.1 4.6e-06 26.6 13.1 2.1 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 GAX15113.1 - 2.7e-07 30.5 19.0 2.7e-07 30.5 19.0 2.0 2 0 0 2 2 2 1 MYND finger TMEM151 PF14857.6 GAX15113.1 - 0.0023 16.9 0.4 0.0078 15.2 0.3 1.8 2 0 0 2 2 2 1 TMEM151 family SoxE PF06525.11 GAX15113.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain MgtE PF01769.16 GAX15114.1 - 0.0081 16.5 4.5 0.34 11.3 0.5 2.3 2 0 0 2 2 2 2 Divalent cation transporter DUF2207 PF09972.9 GAX15114.1 - 0.041 12.7 0.2 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ABC_membrane PF00664.23 GAX15114.1 - 0.26 10.9 6.0 0.11 12.2 0.5 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region DUF4886 PF16227.5 GAX15115.1 - 0.00014 21.2 0.0 0.2 10.8 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4886) DUF4886 PF16227.5 GAX15116.1 - 3.5e-07 29.7 0.0 5.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4886) DUF1336 PF07059.12 GAX15117.1 - 3.5e-46 158.1 0.0 5e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 GAX15117.1 - 0.00088 19.8 0.0 0.01 16.3 0.0 2.4 1 1 0 1 1 1 1 PH domain GFO_IDH_MocA PF01408.22 GAX15118.1 - 7.8e-20 71.9 0.0 1e-19 71.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 GAX15118.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 GAX15118.1 - 0.15 12.7 0.0 0.22 12.2 0.0 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Mpp10 PF04006.12 GAX15119.1 - 1.7e-108 363.7 85.3 4.6e-98 329.3 39.1 2.1 1 1 1 2 2 2 2 Mpp10 protein ABATE PF07336.11 GAX15119.1 - 0.068 13.8 1.4 0.18 12.5 1.4 1.7 1 0 0 1 1 1 0 Putative stress-induced transcription regulator XRN_N PF03159.18 GAX15119.1 - 6.7 6.0 9.6 0.84 9.0 3.9 2.4 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus MMR_HSR1 PF01926.23 GAX15120.1 - 8.5e-19 67.7 0.0 2.1e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX15120.1 - 0.00023 21.1 0.1 0.022 14.7 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 GAX15120.1 - 0.0004 19.9 0.1 0.005 16.4 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX15120.1 - 0.0046 17.0 1.9 2.1 8.3 0.2 3.2 2 1 1 3 3 3 2 Dynamin family Roc PF08477.13 GAX15120.1 - 0.15 12.3 0.1 0.55 10.5 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Methyltr_RsmB-F PF01189.17 GAX15121.1 - 5e-12 45.9 0.2 1.1e-11 44.7 0.1 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 GAX15121.1 - 3e-06 27.1 0.7 1.2e-05 25.2 1.1 1.7 2 0 0 2 2 2 1 PUA domain FtsJ PF01728.19 GAX15121.1 - 0.035 14.2 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 GAX15121.1 - 0.091 13.5 0.0 0.28 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain SF1-HH PF16275.5 GAX15122.1 - 2.6e-16 60.0 5.1 1.5e-15 57.5 5.1 2.3 1 1 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 GAX15122.1 - 2.3e-10 40.1 0.8 4.8e-10 39.1 0.8 1.5 1 0 0 1 1 1 1 KH domain PHD_4 PF16866.5 GAX15122.1 - 0.0012 18.9 2.3 0.0028 17.7 2.3 1.6 1 0 0 1 1 1 1 PHD-finger zf-CCHC PF00098.23 GAX15122.1 - 0.0017 18.3 8.3 0.0018 18.3 2.0 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GAX15122.1 - 0.0041 17.0 2.2 0.014 15.4 2.2 1.9 1 1 0 1 1 1 1 Zinc knuckle SlyX PF04102.12 GAX15122.1 - 3.1 8.5 6.9 0.51 11.0 1.9 2.4 2 0 0 2 2 2 0 SlyX Ice_nucleation PF00818.17 GAX15123.1 - 0.078 13.1 6.6 2 8.7 6.6 3.7 1 0 0 1 1 1 0 Ice nucleation protein repeat EF-hand_7 PF13499.6 GAX15124.1 - 0.012 16.1 2.8 0.042 14.3 0.9 2.3 2 0 0 2 2 2 0 EF-hand domain pair MSA-2c PF12238.8 GAX15124.1 - 0.029 14.4 0.1 0.029 14.4 0.1 2.6 3 0 0 3 3 3 0 Merozoite surface antigen 2c EF-hand_6 PF13405.6 GAX15124.1 - 0.86 9.7 3.5 15 5.9 0.1 3.3 4 0 0 4 4 4 0 EF-hand domain NAC PF01849.18 GAX15125.1 - 2.4e-24 85.1 0.1 4.2e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 NAC domain OSK PF17182.4 GAX15125.1 - 0.17 11.1 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 OSK domain TPR_2 PF07719.17 GAX15126.1 - 7.2e-28 94.4 21.9 5.5e-05 23.0 0.1 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 GAX15126.1 - 1.3e-25 87.8 28.3 0.0022 18.7 0.0 10.5 6 2 5 11 11 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 GAX15126.1 - 1.5e-23 83.0 13.7 2.2e-05 24.9 0.1 7.2 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAX15126.1 - 2.1e-22 79.2 24.8 0.00038 20.7 0.2 8.0 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15126.1 - 2.7e-22 77.6 8.6 0.00018 21.2 0.1 9.6 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAX15126.1 - 2.9e-22 79.0 29.6 4.4e-08 33.6 0.3 8.5 8 2 1 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX15126.1 - 1.8e-21 74.5 6.2 0.0071 16.5 0.1 11.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAX15126.1 - 1.3e-20 72.2 0.7 0.046 14.1 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX15126.1 - 1.8e-14 52.6 12.6 0.11 12.6 0.0 9.8 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAX15126.1 - 1.7e-09 37.7 20.0 8.5 7.3 0.0 10.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX15126.1 - 2.8e-09 36.6 18.0 1.8e-05 24.1 0.1 6.1 3 3 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX15126.1 - 5.2e-08 32.9 13.8 0.18 12.0 0.1 7.0 6 1 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX15126.1 - 1.3e-07 31.8 0.2 0.41 10.9 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAX15126.1 - 7.6e-07 28.7 6.9 0.00062 19.4 0.0 6.2 7 1 0 7 7 7 1 TPR repeat Suf PF05843.14 GAX15126.1 - 1.7e-05 25.0 0.2 0.65 9.9 0.0 3.8 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_10 PF13374.6 GAX15126.1 - 0.00019 21.2 19.4 0.38 10.7 0.3 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat PPR PF01535.20 GAX15126.1 - 0.0013 18.9 4.9 3.4 8.1 0.3 6.0 7 0 0 7 7 7 1 PPR repeat MIT PF04212.18 GAX15126.1 - 0.016 15.2 5.9 34 4.6 0.2 6.2 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 GAX15126.1 - 0.063 13.9 17.4 17 6.4 0.3 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAX15126.1 - 0.11 12.5 8.9 58 3.7 0.0 6.4 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 Adap_comp_sub PF00928.21 GAX15128.1 - 3.8e-64 216.6 0.0 4.6e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAX15128.1 - 0.0011 18.9 0.0 0.0037 17.2 0.0 1.8 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Longin PF13774.6 GAX15128.1 - 0.0044 17.0 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Chlorosome_CsmC PF11098.8 GAX15128.1 - 0.034 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF4869 PF16163.5 GAX15128.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) LON_substr_bdg PF02190.16 GAX15129.1 - 2.2e-09 37.5 0.0 2.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DEAD PF00270.29 GAX15130.1 - 6.3e-40 136.8 0.2 9.3e-40 136.3 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX15130.1 - 4e-25 88.3 0.0 2.7e-24 85.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAX15130.1 - 2.9e-11 43.4 0.1 5.8e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAX15130.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX15130.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 GAX15130.1 - 0.057 12.8 1.1 0.15 11.3 0.0 2.2 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit RRM_1 PF00076.22 GAX15132.1 - 2.5e-11 43.2 0.0 1.1e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC3_N PF07034.11 GAX15132.1 - 0.0022 17.2 2.1 0.0035 16.5 2.1 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF5619 PF18505.1 GAX15132.1 - 0.019 14.9 0.6 0.034 14.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) Pepsin-I3 PF06394.13 GAX15132.1 - 0.34 11.1 2.7 26 5.1 1.3 2.6 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain HA PF03457.14 GAX15133.1 - 4.1e-19 68.7 1.4 5.3e-09 36.3 0.0 3.8 4 1 0 4 4 4 3 Helicase associated domain Acetyltransf_1 PF00583.25 GAX15134.1 - 1.4e-11 44.6 0.1 3.4e-11 43.4 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX15134.1 - 1.6e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX15134.1 - 2.4e-07 31.1 0.0 4.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX15134.1 - 0.00086 19.2 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAX15134.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAX15134.1 - 0.052 13.2 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Asp_Arg_Hydrox PF05118.15 GAX15135.1 - 8.7e-37 126.4 0.0 4.2e-36 124.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase MMR_HSR1 PF01926.23 GAX15136.1 - 2.7e-21 75.8 0.0 1.8e-20 73.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase YchF-GTPase_C PF06071.13 GAX15136.1 - 2.3e-08 34.1 0.5 2.3e-08 34.1 0.5 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF933) FeoB_N PF02421.18 GAX15136.1 - 5.4e-07 29.3 0.0 3e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Lar_N PF09861.9 GAX15137.1 - 4.7e-11 42.2 0.0 1.5e-05 24.3 0.0 2.9 2 1 0 2 2 2 2 Lactate racemase N-terminal domain Histone PF00125.24 GAX15138.1 - 9.5e-54 181.3 2.2 1.1e-53 181.1 2.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GAX15138.1 - 0.00014 22.5 1.6 0.00016 22.3 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GAX15138.1 - 0.00037 20.6 0.5 0.00057 20.0 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX15138.1 - 0.00044 20.6 0.0 0.00068 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAX15138.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAX15138.1 - 0.086 12.9 0.1 0.16 12.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Lung_7-TM_R PF06814.13 GAX15139.1 - 2.3e-44 151.8 11.0 3.1e-44 151.4 11.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3566 PF12089.8 GAX15139.1 - 0.076 13.4 4.3 0.26 11.7 4.3 2.0 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) DUF2207 PF09972.9 GAX15139.1 - 1.1 7.9 4.8 2.1 7.0 4.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DNA_pol_B PF00136.21 GAX15140.1 - 8.3e-137 456.6 0.2 1.1e-136 456.2 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAX15140.1 - 2.3e-70 237.4 0.0 3.4e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAX15140.1 - 7e-09 36.0 0.9 1.6e-08 34.9 0.9 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 GAX15140.1 - 7e-05 21.9 4.8 0.01 14.8 0.3 2.4 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 GAX15140.1 - 0.023 14.4 0.1 0.081 12.6 0.1 2.0 2 0 0 2 2 2 0 3'-5' exonuclease TMEM234 PF10639.9 GAX15141.1 - 4.8e-27 94.3 2.7 1.3e-26 92.9 2.7 1.6 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 GAX15141.1 - 0.0027 17.9 3.6 0.012 15.8 1.4 2.0 1 1 1 2 2 2 1 EamA-like transporter family NifU_N PF01592.16 GAX15142.1 - 1.6e-54 183.4 0.1 2e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain HORMA PF02301.18 GAX15143.1 - 1.4e-20 73.9 0.1 1.7e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 HORMA domain Peptidase_M16 PF00675.20 GAX15144.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX15144.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain Inhibitor_I53 PF11714.8 GAX15144.1 - 0.13 12.5 1.7 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Aldo_ket_red PF00248.21 GAX15145.1 - 9.1e-63 212.2 0.0 1.2e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.26 GAX15146.1 - 7.9e-19 67.7 0.0 1.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Tox-HNH-HHH PF15637.6 GAX15146.1 - 0.16 12.1 0.0 0.58 10.3 0.0 1.8 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Dus PF01207.17 GAX15147.1 - 5.6e-51 173.5 0.0 7.9e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 GAX15147.1 - 3.3e-05 23.8 10.0 0.0085 16.1 0.7 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 GAX15147.1 - 6.3e-05 22.8 11.7 0.0087 15.9 0.3 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAX15147.1 - 0.021 14.6 1.8 0.021 14.6 1.8 2.8 3 0 0 3 3 3 0 CCCH-type zinc finger Torus PF16131.5 GAX15147.1 - 0.039 14.6 0.6 0.039 14.6 0.6 2.2 1 1 1 2 2 2 0 Torus domain Symplekin_C PF12295.8 GAX15148.1 - 9.3e-37 126.9 0.0 2e-36 125.9 0.0 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 GAX15148.1 - 7.2e-13 48.7 0.0 4.1e-10 39.7 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3453) PfkB PF00294.24 GAX15149.1 - 3e-27 95.7 0.1 2.2e-15 56.7 0.0 3.0 3 0 0 3 3 3 3 pfkB family carbohydrate kinase Phage_term_smal PF05944.12 GAX15149.1 - 0.018 15.0 0.3 0.037 14.0 0.3 1.4 1 0 0 1 1 1 0 Phage small terminase subunit Phage_GP20 PF06810.11 GAX15149.1 - 0.031 14.1 1.1 0.084 12.7 1.1 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 TPR_19 PF14559.6 GAX15152.1 - 5.7e-09 36.3 4.8 0.41 11.2 0.0 6.9 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX15152.1 - 1.7e-06 28.4 23.7 0.0067 17.2 1.3 9.1 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX15152.1 - 0.05 14.3 10.6 0.39 11.4 2.4 5.0 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX15152.1 - 0.051 13.9 16.5 0.16 12.3 0.1 5.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX15152.1 - 0.94 9.9 6.6 3.2 8.2 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX15152.1 - 2 8.7 17.8 0.12 12.5 1.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX15152.1 - 4.8 7.4 6.0 7.7 6.8 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 GAX15153.1 - 1.4e-34 119.4 0.0 2.3e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX15153.1 - 2e-25 89.3 0.0 2.1e-24 86.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX15153.1 - 2.7e-06 27.5 0.0 7.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Thymidylat_synt PF00303.19 GAX15155.1 - 5.4e-119 396.2 0.0 7.2e-119 395.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 GAX15155.1 - 1.9e-43 148.0 0.0 6.4e-43 146.2 0.0 1.8 2 0 0 2 2 2 1 Dihydrofolate reductase Cofilin_ADF PF00241.20 GAX15156.1 - 2.9e-05 23.9 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.25 GAX15157.1 - 8.4e-40 136.8 0.0 1.5e-39 135.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15157.1 - 1.1e-18 67.4 0.0 2.1e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAX15157.1 - 9.4e-06 25.7 0.0 2.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX15157.1 - 0.00012 21.0 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX15157.1 - 0.0012 18.2 0.0 0.0052 16.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAX15157.1 - 0.0056 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 GAX15157.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_14 PF13428.6 GAX15158.1 - 4.3 8.4 8.6 7.5 7.7 0.4 3.8 1 1 3 4 4 4 0 Tetratricopeptide repeat NifU PF01106.17 GAX15159.1 - 2.3e-23 82.1 1.1 4e-21 74.9 0.1 2.5 2 0 0 2 2 2 2 NifU-like domain DUF2012 PF09430.10 GAX15160.1 - 9.5e-24 83.9 0.0 1.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 GAX15160.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 GAX15160.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Pkinase PF00069.25 GAX15161.1 - 1.4e-58 198.3 0.0 1.6e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15161.1 - 1.1e-22 80.6 0.0 1.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX15161.1 - 1.7e-05 24.3 0.0 2.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAX15161.1 - 0.0081 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX15161.1 - 0.029 13.3 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAX15161.1 - 0.056 12.8 0.2 0.36 10.1 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L1 PF00687.21 GAX15162.1 - 3.5e-43 147.7 1.8 4.4e-43 147.4 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Sulfotransfer_3 PF13469.6 GAX15163.1 - 0.00054 20.4 0.0 0.00092 19.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family TSP_3 PF02412.18 GAX15164.1 - 1.8e-06 27.6 122.7 0.015 15.0 7.0 13.2 3 2 10 13 13 13 13 Thrombospondin type 3 repeat MAT1 PF06391.13 GAX15165.1 - 1.9e-27 96.5 16.0 2.7e-27 96.0 16.0 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.25 GAX15165.1 - 5.3e-07 29.4 4.9 1.3e-06 28.1 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX15165.1 - 2.8e-06 27.6 4.9 5.6e-06 26.6 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAX15165.1 - 1.5e-05 25.1 2.5 1.5e-05 25.1 2.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAX15165.1 - 1.8e-05 24.6 3.6 4.2e-05 23.5 3.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX15165.1 - 8.6e-05 22.3 9.9 0.00033 20.4 9.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX15165.1 - 0.0001 22.2 8.9 0.00048 20.0 9.2 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX15165.1 - 0.00022 21.0 7.8 0.00086 19.1 7.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX15165.1 - 0.00051 20.3 3.9 0.0012 19.1 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain UvrD-helicase PF00580.21 GAX15165.1 - 0.0008 19.0 2.5 0.001 18.7 2.5 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain EFG_C PF00679.24 GAX15165.1 - 0.0029 17.6 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Prok-RING_4 PF14447.6 GAX15165.1 - 0.0029 17.4 5.4 0.011 15.5 5.6 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 GAX15165.1 - 0.014 15.5 4.9 0.033 14.3 4.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 GAX15165.1 - 0.058 13.3 7.7 0.056 13.3 5.1 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4148 PF13663.6 GAX15165.1 - 0.16 12.1 1.5 0.33 11.2 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) FHIPEP PF00771.20 GAX15165.1 - 0.23 9.9 3.8 0.28 9.6 3.8 1.1 1 0 0 1 1 1 0 FHIPEP family zf-FPG_IleRS PF06827.14 GAX15165.1 - 0.69 9.8 0.1 0.69 9.8 0.1 3.7 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-RING_4 PF14570.6 GAX15165.1 - 1.2 9.0 7.4 0.19 11.5 3.3 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Acetone_carb_G PF08882.11 GAX15165.1 - 1.2 9.3 8.8 3.1 8.0 0.2 3.8 1 1 2 4 4 4 0 Acetone carboxylase gamma subunit Response_reg PF00072.24 GAX15166.1 - 0.083 13.1 0.0 0.22 11.7 0.0 1.8 1 1 0 1 1 1 0 Response regulator receiver domain CTD_bind PF04818.13 GAX15166.1 - 0.19 12.5 0.1 1.2 10.0 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Taxilin PF09728.9 GAX15168.1 - 1.3e-07 31.2 5.4 1.3e-07 31.2 5.4 4.1 2 1 2 4 4 4 1 Myosin-like coiled-coil protein Cep57_MT_bd PF06657.13 GAX15168.1 - 0.027 14.9 0.2 0.027 14.9 0.2 7.1 4 2 4 8 8 8 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 GAX15168.1 - 5.6 5.7 92.6 0.67 8.8 10.5 5.3 2 1 4 6 6 6 0 Spc7 kinetochore protein bHLH-MYC_N PF14215.6 GAX15169.1 - 8.5e-06 26.2 0.0 2.7e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal GAF_2 PF13185.6 GAX15169.1 - 0.056 13.7 0.0 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 GAF domain Spore_GerAC PF05504.11 GAX15169.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal bHLH-MYC_N PF14215.6 GAX15170.1 - 2.7e-05 24.5 0.7 0.00027 21.2 0.0 2.5 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal TFIIA PF03153.13 GAX15170.1 - 3.9 7.4 12.2 7.7 6.4 12.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.6 GAX15170.1 - 6.5 7.2 9.1 19 5.7 9.1 1.8 1 0 0 1 1 1 0 Ring finger domain Vma12 PF11712.8 GAX15171.1 - 1.5e-08 34.8 0.1 2.3e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DNA_pol_E_B PF04042.16 GAX15172.1 - 6.2e-27 94.3 0.1 1e-26 93.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Cyclin_N PF00134.23 GAX15174.1 - 1e-08 35.0 0.0 3e-08 33.4 0.0 1.7 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX15174.1 - 2.6e-08 33.9 0.4 2.6e-08 33.9 0.4 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain Peptidase_S28 PF05577.12 GAX15176.1 - 6.6e-50 170.2 0.1 5.2e-41 140.9 0.0 3.2 2 1 1 3 3 3 3 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 GAX15176.1 - 0.0037 17.9 2.3 0.0056 17.3 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX15176.1 - 0.0044 16.5 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAX15176.1 - 0.0092 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX15176.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 GAX15176.1 - 0.091 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 BTB PF00651.31 GAX15177.1 - 2.6e-06 27.6 0.2 0.00021 21.5 0.0 2.8 3 0 0 3 3 3 1 BTB/POZ domain Ran-binding PF05508.11 GAX15177.1 - 0.0018 17.3 4.4 0.003 16.6 4.0 1.5 1 1 0 1 1 1 1 RanGTP-binding protein DUF745 PF05335.13 GAX15177.1 - 0.048 13.4 5.3 0.089 12.5 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BRE1 PF08647.11 GAX15177.1 - 0.08 13.0 7.2 0.25 11.5 7.2 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FapA PF03961.13 GAX15177.1 - 0.68 8.5 5.8 1 7.9 5.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PEP-utilisers_N PF05524.13 GAX15177.1 - 2.1 8.5 5.9 2.7 8.2 1.3 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal SWIM PF04434.17 GAX15178.1 - 3.3 7.5 6.4 11 5.8 6.4 1.9 1 1 0 1 1 1 0 SWIM zinc finger LRR_6 PF13516.6 GAX15179.1 - 7.2e-10 38.1 11.3 0.00071 19.4 0.0 7.1 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 GAX15179.1 - 0.13 12.7 0.1 0.13 12.7 0.1 6.5 3 3 4 8 8 8 0 Leucine Rich repeats (2 copies) SpoU_sub_bind PF08032.12 GAX15179.1 - 0.16 12.2 0.0 10 6.5 0.0 2.9 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding LRR_1 PF00560.33 GAX15179.1 - 6.2 7.8 13.9 5.7 7.9 0.0 6.6 7 2 0 7 7 7 0 Leucine Rich Repeat NifU PF01106.17 GAX15180.1 - 8.6e-28 96.3 0.2 1.3e-27 95.7 0.2 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 GAX15180.1 - 5.6e-25 87.2 0.0 1.4e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Bunya_G1 PF03557.15 GAX15180.1 - 0.16 9.9 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 Ank_2 PF12796.7 GAX15181.1 - 1.3e-10 41.7 0.0 3.4e-05 24.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX15181.1 - 2.2e-08 33.7 0.5 0.022 15.2 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX15181.1 - 6.1e-06 26.4 0.0 0.055 13.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAX15181.1 - 5.8e-05 23.3 0.1 0.056 13.8 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX15181.1 - 0.0041 17.7 0.1 0.05 14.2 0.0 2.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Pkinase PF00069.25 GAX15182.1 - 7.5e-38 130.4 0.0 1.1e-36 126.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15182.1 - 4.8e-29 101.4 0.0 1.7e-28 99.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX15182.1 - 0.00064 19.1 0.0 0.0024 17.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FAA_hydrolase PF01557.18 GAX15183.1 - 3.4e-53 180.5 0.0 4.9e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAX15183.1 - 8e-20 71.0 0.0 1.5e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_3 PF13417.6 GAX15183.1 - 8.9e-13 48.5 0.0 2.5e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX15183.1 - 1.6e-12 47.6 0.0 3.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX15183.1 - 5.2e-11 42.7 0.0 1.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CNDH2_C PF16858.5 GAX15184.1 - 2.3e-64 218.1 1.2 4.3e-64 217.2 0.2 1.8 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 GAX15184.1 - 4.1e-31 107.5 1.4 6.9e-30 103.6 0.2 2.6 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Mito_carr PF00153.27 GAX15185.1 - 7.6e-53 176.4 0.6 1.6e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX15185.1 - 0.051 12.7 0.2 4.4 6.4 0.0 2.8 3 1 0 3 3 3 0 Gammaproteobacterial serine protease CREPT PF16566.5 GAX15186.1 - 0.043 14.0 0.2 0.053 13.7 0.2 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2115 PF09888.9 GAX15186.1 - 0.054 14.0 0.1 0.063 13.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) HA PF03457.14 GAX15187.1 - 1.7e-47 159.6 9.9 3.6e-21 75.2 0.3 3.4 3 1 0 3 3 3 3 Helicase associated domain LPD22 PF18834.1 GAX15187.1 - 0.11 12.7 0.4 0.45 10.8 0.2 1.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 Chloroa_b-bind PF00504.21 GAX15188.1 - 3.1e-24 86.3 0.1 1.2e-23 84.4 0.1 1.8 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX15189.1 - 1.8e-26 93.6 0.0 5.9e-26 91.9 0.0 1.7 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX15190.1 - 3.2e-27 96.0 0.0 1.2e-26 94.2 0.0 1.8 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Exo_endo_phos PF03372.23 GAX15192.1 - 1.2e-07 31.5 0.0 6.9e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_isomerase PF00160.21 GAX15193.1 - 1.5e-10 41.5 0.0 3.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trypsin PF00089.26 GAX15194.1 - 1.8e-42 145.7 0.0 2.4e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin 2OG-FeII_Oxy_3 PF13640.6 GAX15195.1 - 0.019 15.9 0.0 0.051 14.5 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily GFO_IDH_MocA PF01408.22 GAX15196.1 - 6.1e-07 30.3 0.0 1.2e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CBS PF00571.28 GAX15198.1 - 6.1e-19 68.2 0.7 4.7e-11 43.0 0.3 2.4 2 1 0 2 2 2 2 CBS domain NETI PF14044.6 GAX15198.1 - 0.16 11.8 0.1 0.43 10.3 0.1 1.7 1 0 0 1 1 1 0 NETI protein SNF2_N PF00176.23 GAX15199.1 - 1.7e-37 128.9 0.1 4.8e-37 127.5 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX15199.1 - 3.7e-23 82.0 0.1 1.4e-22 80.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAX15199.1 - 1.1e-05 24.8 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAX15199.1 - 1.1e-05 25.5 0.0 3.7e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit S-methyl_trans PF02574.16 GAX15200.1 - 3.8e-55 187.6 0.0 4.3e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase MerR-DNA-bind PF09278.11 GAX15200.1 - 0.099 13.2 0.0 3.1 8.4 0.0 2.4 2 0 0 2 2 2 0 MerR, DNA binding DUF1749 PF08538.10 GAX15203.1 - 5.1e-56 190.0 0.0 6.1e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 GAX15203.1 - 9.3e-06 25.1 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAX15203.1 - 0.00025 21.0 0.2 0.00059 19.7 0.1 1.6 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.20 GAX15203.1 - 0.015 14.9 0.0 0.065 12.9 0.0 2.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold DUF900 PF05990.12 GAX15203.1 - 0.059 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1295 PF06966.12 GAX15204.1 - 2.6e-29 102.4 9.3 3.8e-29 101.9 9.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) TrbL PF04610.14 GAX15204.1 - 0.0033 17.2 1.2 0.0078 16.0 1.2 1.7 1 1 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Methyltransf_28 PF02636.17 GAX15207.1 - 1.3e-27 97.1 0.3 2e-27 96.4 0.3 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 GAX15207.1 - 1.6e-05 25.6 0.0 3.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 GAX15207.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 GAX15207.1 - 0.011 16.4 0.0 0.037 14.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAX15207.1 - 0.052 13.3 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AAA_12 PF13087.6 GAX15209.1 - 1.6e-42 145.4 0.0 3.5e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX15209.1 - 1.2e-29 103.9 0.0 3.1e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX15209.1 - 1.4e-12 48.2 0.0 1.9e-11 44.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX15209.1 - 1.3e-11 44.6 0.1 1.6e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 GAX15209.1 - 3.5e-06 26.8 0.0 0.00011 21.9 0.0 2.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 GAX15209.1 - 7.5e-05 22.1 0.0 0.0032 16.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 GAX15209.1 - 0.0004 20.4 0.0 0.0013 18.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.29 GAX15209.1 - 0.0023 18.4 0.3 0.08 13.4 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX15209.1 - 0.013 15.5 0.2 0.079 13.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ING PF12998.7 GAX15209.1 - 0.037 14.6 0.9 4.3 8.0 0.1 3.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding AAA_16 PF13191.6 GAX15209.1 - 0.039 14.3 0.1 0.29 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GAX15209.1 - 0.049 13.9 1.3 1.3 9.3 0.1 3.5 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 GAX15209.1 - 0.1 11.6 0.0 0.37 9.8 0.0 1.9 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 GAX15209.1 - 0.16 11.4 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein XRN_N PF03159.18 GAX15210.1 - 5.5e-37 127.5 0.0 1.1e-36 126.5 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Asp2 PF16929.5 GAX15210.1 - 0.054 12.5 0.2 0.085 11.8 0.2 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter PCMT PF01135.19 GAX15212.1 - 9.5e-51 172.5 0.0 1.2e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAX15212.1 - 1.4e-07 31.5 0.0 2.1e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX15212.1 - 2.5e-07 31.3 0.0 7.1e-07 29.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX15212.1 - 2.9e-07 30.6 0.0 4.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX15212.1 - 8.4e-06 25.7 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX15212.1 - 2.4e-05 23.9 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX15212.1 - 8.7e-05 22.1 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain AviRa PF11599.8 GAX15212.1 - 9e-05 22.0 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 GAX15212.1 - 0.00014 22.6 0.0 0.0003 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX15212.1 - 0.00023 21.8 0.0 0.00054 20.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAX15212.1 - 0.0014 18.8 0.0 0.007 16.5 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAX15212.1 - 0.0023 17.3 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 GAX15212.1 - 0.045 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Utp8 PF10395.9 GAX15212.1 - 0.096 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Utp8 family Methyltransf_9 PF08003.11 GAX15212.1 - 0.11 11.4 0.6 1.5 7.6 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 GAX15212.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain EAP30 PF04157.16 GAX15213.1 - 1.1e-23 83.7 1.6 1.7e-23 83.2 1.6 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 GAX15213.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 2-Hacid_dh_C PF02826.19 GAX15214.1 - 8e-52 175.2 0.0 2e-51 173.9 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 GAX15214.1 - 0.00016 21.8 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 GAX15214.1 - 0.0059 17.1 0.0 0.025 15.1 0.0 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh PF00389.30 GAX15214.1 - 0.027 14.1 0.0 0.17 11.5 0.0 2.1 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAX15214.1 - 0.029 14.5 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 GAX15214.1 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 GAX15214.1 - 0.053 14.4 0.0 1.3 9.8 0.0 2.7 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ELFV_dehydrog PF00208.21 GAX15214.1 - 0.07 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.19 GAX15214.1 - 0.15 10.8 0.0 1.5 7.5 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.17 GAX15214.1 - 0.21 12.2 0.1 0.65 10.6 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent F-box-like PF12937.7 GAX15215.1 - 0.0033 17.3 0.1 0.015 15.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAX15215.1 - 0.067 13.1 0.1 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 F-box domain Cpn60_TCP1 PF00118.24 GAX15216.1 - 4.9e-139 464.1 1.1 5.7e-139 463.9 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Beta_helix_2 PF18835.1 GAX15216.1 - 0.092 12.5 0.8 3.3 7.6 0.0 3.3 3 0 0 3 3 3 0 Beta helix repeat of Inulin fructotransferase MOZART1 PF12554.8 GAX15216.1 - 0.15 11.9 1.8 0.24 11.2 0.2 2.2 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF3172 PF11371.8 GAX15217.1 - 9.8e-59 197.0 0.3 1.2e-58 196.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) PBP1_TM PF14812.6 GAX15217.1 - 0.52 10.7 5.1 1.1 9.7 5.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SelR PF01641.18 GAX15218.1 - 1.8e-28 99.0 0.0 3.2e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 SelR domain DUF692 PF05114.13 GAX15222.1 - 0.032 13.4 0.1 0.058 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF692) NQRA PF05896.11 GAX15222.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RVT_3 PF13456.6 GAX15225.1 - 1.1e-42 144.7 0.0 1.4e-25 89.5 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase-like CCAP PF11105.8 GAX15225.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a HNH_3 PF13392.6 GAX15226.1 - 9.6e-05 22.1 3.2 0.00084 19.1 0.1 2.8 2 0 0 2 2 2 1 HNH endonuclease AP2 PF00847.20 GAX15226.1 - 0.0068 16.6 0.4 0.02 15.1 0.4 1.9 1 0 0 1 1 1 1 AP2 domain RNA_pol_Rpc4 PF05132.14 GAX15226.1 - 0.015 15.7 5.0 0.015 15.7 5.0 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Vps53_N PF04100.12 GAX15227.1 - 4.9e-58 196.9 11.0 2.9e-33 115.4 6.0 3.2 2 1 0 2 2 2 2 Vps53-like, N-terminal Sec6 PF06046.13 GAX15227.1 - 1e-07 30.8 0.4 7.4e-06 24.6 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec6 COG7 PF10191.9 GAX15227.1 - 6.1e-06 24.8 6.9 0.00028 19.3 0.1 3.0 3 0 0 3 3 3 2 Golgi complex component 7 (COG7) DUF2451 PF10474.9 GAX15227.1 - 5.3e-05 23.1 1.3 0.00038 20.3 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Tropomyosin_1 PF12718.7 GAX15227.1 - 0.0019 18.4 5.2 0.0069 16.6 5.2 1.9 1 0 0 1 1 1 1 Tropomyosin like Vps54_N PF10475.9 GAX15227.1 - 0.0023 17.3 2.6 0.0023 17.3 2.6 1.6 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 GAX15227.1 - 0.0081 16.3 5.6 0.0081 16.3 5.6 2.0 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Nab1 PF04902.12 GAX15227.1 - 0.044 14.2 1.8 0.33 11.3 2.1 2.4 2 0 0 2 2 1 0 Conserved region in Nab1 DUF1664 PF07889.12 GAX15227.1 - 0.079 13.0 12.0 0.38 10.8 6.5 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) FUSC PF04632.12 GAX15227.1 - 0.13 10.8 5.3 0.24 9.9 5.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG2 PF06148.11 GAX15227.1 - 0.19 11.8 9.6 0.048 13.7 2.8 3.1 4 0 0 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 GAX15227.1 - 0.24 10.2 10.2 0.047 12.6 6.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein LXG PF04740.12 GAX15227.1 - 0.4 10.4 8.4 1.4 8.6 4.8 2.6 2 0 0 2 2 2 0 LXG domain of WXG superfamily Cauli_AT PF03233.13 GAX15227.1 - 0.46 10.4 2.9 0.75 9.7 0.1 2.6 2 1 1 3 3 3 0 Aphid transmission protein SKA2 PF16740.5 GAX15227.1 - 0.75 9.6 12.9 0.59 9.9 4.4 3.9 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 GAX15227.1 - 1.2 9.4 7.2 0.94 9.7 4.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4337 PF14235.6 GAX15227.1 - 1.5 8.9 8.4 1 9.5 6.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) Laminin_II PF06009.12 GAX15227.1 - 1.5 8.8 11.4 3.7 7.5 6.5 2.5 2 0 0 2 2 2 0 Laminin Domain II TerB_C PF15615.6 GAX15227.1 - 1.6 9.0 7.2 7.7 6.8 1.2 2.9 3 0 0 3 3 3 0 TerB-C domain KxDL PF10241.9 GAX15227.1 - 2.2 8.6 13.3 12 6.2 0.2 2.9 3 0 0 3 3 2 0 Uncharacterized conserved protein Filament PF00038.21 GAX15227.1 - 2.5 7.6 11.7 1.5 8.3 6.8 2.5 3 0 0 3 3 3 0 Intermediate filament protein CREPT PF16566.5 GAX15227.1 - 3 8.0 9.5 1.5 9.0 6.2 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CENP-F_leu_zip PF10473.9 GAX15227.1 - 3.2 7.8 12.1 0.53 10.3 6.6 2.5 3 0 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 GAX15227.1 - 4.1 7.6 12.5 1.6 8.9 8.8 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1690 PF07956.11 GAX15227.1 - 4.6 7.7 12.7 4.8 7.6 4.8 3.1 3 0 0 3 3 2 0 Protein of Unknown function (DUF1690) Exonuc_VII_L PF02601.15 GAX15227.1 - 6.6 6.2 11.1 1.8 8.1 7.4 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 GAX15227.1 - 9.2 6.8 11.2 31 5.1 0.1 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 GAX15227.1 - 10 6.5 9.8 0.61 10.4 2.8 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF5082) DEAD PF00270.29 GAX15228.1 - 5.8e-33 114.1 0.0 1e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX15228.1 - 6.5e-26 90.8 0.0 4.5e-25 88.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sel1 PF08238.12 GAX15229.1 - 2.4e-17 63.0 4.2 5.7e-07 30.0 0.1 4.9 6 0 0 6 6 6 3 Sel1 repeat Tcf25 PF04910.14 GAX15230.1 - 2.1e-37 129.0 0.0 3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Secretogranin_V PF05281.11 GAX15230.1 - 0.019 14.6 1.2 1.7 8.2 2.0 2.2 2 0 0 2 2 2 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) CRA PF06589.11 GAX15230.1 - 4.3 7.4 6.0 8.6 6.5 6.0 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) EPSP_synthase PF00275.20 GAX15231.1 - 4.5e-134 447.3 0.0 5.2e-134 447.1 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) PBP-Tp47_c PF14888.6 GAX15232.1 - 0.23 11.4 0.0 1.7 8.5 0.0 2.0 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain C RNB PF00773.19 GAX15233.1 - 1e-54 186.1 0.0 1.5e-54 185.5 0.0 1.3 1 0 0 1 1 1 1 RNB domain ATP_bind_1 PF03029.17 GAX15235.1 - 0.0095 15.7 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 GAX15235.1 - 0.015 15.7 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX15235.1 - 0.042 13.6 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX15235.1 - 0.042 14.1 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAX15235.1 - 0.061 13.5 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX15235.1 - 0.073 13.6 0.0 0.12 12.9 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAX15235.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAX15235.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 GAX15237.1 - 6.5e-14 52.1 5.6 0.034 15.0 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat 2OG-FeII_Oxy_3 PF13640.6 GAX15238.1 - 1.2e-17 64.6 0.0 2.6e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX15238.1 - 2.5e-05 24.7 0.0 4.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Choline_transpo PF04515.12 GAX15239.1 - 3.3e-70 236.9 31.0 3.3e-70 236.9 31.0 2.0 1 1 0 2 2 2 1 Plasma-membrane choline transporter RraA-like PF03737.15 GAX15240.1 - 1.3e-41 142.2 0.2 1.9e-41 141.7 0.2 1.2 1 0 0 1 1 1 1 Aldolase/RraA Flavi_propep PF01570.17 GAX15240.1 - 0.058 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide PT PF04886.12 GAX15241.1 - 0.019 14.5 11.0 0.019 14.5 11.0 3.0 3 0 0 3 3 3 0 PT repeat Mucin PF01456.17 GAX15241.1 - 0.22 11.5 7.9 0.42 10.6 7.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Cytomega_UL20A PF05984.12 GAX15241.1 - 1.6 9.0 3.8 3.1 8.1 3.8 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein DUF1664 PF07889.12 GAX15242.1 - 0.013 15.5 0.4 0.017 15.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2570 PF10828.8 GAX15242.1 - 0.026 14.3 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) FlaC_arch PF05377.11 GAX15242.1 - 0.065 13.6 0.3 0.84 10.1 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ArsR PF09824.9 GAX15242.1 - 0.1 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Peptidase_S49_N PF08496.10 GAX15242.1 - 0.11 12.6 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec20 PF03908.13 GAX15242.1 - 0.13 12.2 0.3 0.22 11.4 0.3 1.4 1 1 1 2 2 2 0 Sec20 ATPase PF06745.13 GAX15242.1 - 0.18 11.1 0.8 0.34 10.2 0.8 1.5 1 1 0 1 1 1 0 KaiC GCK PF07802.11 GAX15244.1 - 8.3e-05 22.9 2.3 8.3e-05 22.9 2.3 1.9 2 0 0 2 2 2 1 GCK domain DUF2834 PF11196.8 GAX15245.1 - 0.08 13.3 0.3 0.21 12.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) TPR_12 PF13424.6 GAX15246.1 - 2.4e-05 24.6 8.7 0.26 11.6 1.4 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX15246.1 - 3.6e-05 23.6 10.9 0.57 10.4 0.6 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 GAX15246.1 - 0.00012 22.0 10.8 0.00012 22.0 10.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain TPR_16 PF13432.6 GAX15246.1 - 0.00026 21.6 1.6 0.41 11.3 1.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4919 PF16266.5 GAX15246.1 - 0.0004 20.4 0.0 0.00088 19.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4919) zf-RING_2 PF13639.6 GAX15246.1 - 0.00044 20.5 12.2 0.00044 20.5 12.2 1.8 2 0 0 2 2 2 1 Ring finger domain TPR_1 PF00515.28 GAX15246.1 - 0.00051 19.8 10.2 0.41 10.5 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX15246.1 - 0.0014 18.5 0.2 3 8.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX15246.1 - 0.0019 18.8 3.1 19 6.4 1.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 GAX15246.1 - 0.0028 17.5 12.4 0.006 16.4 12.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC3 PF12895.7 GAX15246.1 - 0.0045 17.2 7.0 1.8 8.8 2.9 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 zf-C3HC4_2 PF13923.6 GAX15246.1 - 0.012 15.5 10.8 0.012 15.5 10.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX15246.1 - 0.029 14.0 9.5 0.052 13.2 9.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GAX15246.1 - 0.036 14.1 7.2 0.036 14.1 7.2 1.8 2 0 0 2 2 1 0 RING-type zinc-finger TPR_10 PF13374.6 GAX15246.1 - 0.041 13.8 3.8 2.8 7.9 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX15246.1 - 0.053 14.0 6.1 16 6.1 3.4 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX15246.1 - 0.057 14.1 11.6 1.8 9.4 0.0 4.6 5 1 1 6 6 4 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 GAX15246.1 - 0.13 12.4 10.8 0.32 11.2 10.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAX15246.1 - 0.18 11.7 11.0 0.37 10.7 11.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_8 PF13181.6 GAX15246.1 - 2 8.8 12.2 5.2 7.5 1.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_10 PF16685.5 GAX15246.1 - 2.3 8.4 8.7 5 7.3 8.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 GAX15246.1 - 2.6 8.1 9.0 1.8e+02 2.3 9.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 GAX15246.1 - 6.8 6.6 16.4 0.29 10.9 10.4 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain PIG-U PF06728.13 GAX15248.1 - 1.3e-40 139.6 26.1 1.6e-40 139.4 26.1 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U HMA PF00403.26 GAX15249.1 - 0.0008 19.8 0.7 0.0021 18.5 0.7 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain WD40 PF00400.32 GAX15250.1 - 2.7e-58 192.6 25.1 4.5e-08 33.6 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15250.1 - 1e-15 57.8 2.8 0.034 14.5 0.0 6.2 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 GAX15250.1 - 6.6e-09 36.2 0.0 1.5e-08 35.1 0.0 1.6 1 1 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 GAX15250.1 - 2.7e-06 26.4 6.9 0.046 12.4 0.4 4.9 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX15250.1 - 3.6e-06 26.2 0.6 2.2 7.1 0.0 5.1 3 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAX15250.1 - 3.8e-05 23.7 0.1 0.13 12.1 0.0 3.3 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PGK PF00162.19 GAX15251.1 - 3.6e-153 510.0 0.5 4.2e-153 509.8 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HTH_24 PF13412.6 GAX15251.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 GAX15251.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Ku PF02735.16 GAX15252.1 - 5.4e-25 88.3 0.0 1.2e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAX15252.1 - 1.8e-09 37.7 0.9 3.8e-09 36.6 0.9 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.6 GAX15252.1 - 6e-06 26.9 1.0 7e-05 23.4 1.0 2.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAX15252.1 - 0.0002 21.7 0.2 0.063 13.5 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain Peptidase_S9 PF00326.21 GAX15253.1 - 3.9e-38 131.1 0.0 6.5e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAX15253.1 - 7.1e-11 42.2 0.1 9.2e-07 28.8 0.4 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAX15253.1 - 2.2e-06 27.7 0.0 5.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX15253.1 - 1e-05 24.9 0.0 0.00037 19.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 GAX15253.1 - 1.2e-05 24.2 0.0 2.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 GAX15253.1 - 1.5e-05 24.6 0.0 0.00014 21.5 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 GAX15253.1 - 0.0011 18.7 0.0 0.12 12.0 0.0 2.3 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 GAX15253.1 - 0.035 14.0 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal YcgR PF07317.12 GAX15253.1 - 0.051 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulator YcgR Peptidase_S28 PF05577.12 GAX15253.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Corona_NS4 PF03905.13 GAX15253.1 - 0.51 10.4 2.1 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 DapB_C PF05173.14 GAX15254.1 - 2.1e-19 69.7 0.2 4.3e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 GAX15254.1 - 1.6e-10 41.2 0.0 3.6e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KHA PF11834.8 GAX15254.1 - 0.12 12.4 1.7 0.3 11.2 1.4 1.8 1 1 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Copine PF07002.16 GAX15255.1 - 3.9e-52 176.8 0.0 5.4e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX15255.1 - 1.5e-18 66.9 0.0 2.5e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX15255.1 - 1.1e-06 28.9 0.0 3.2e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 vWA found in TerF C terminus UAE_UbL PF14732.6 GAX15255.1 - 0.12 13.0 0.2 0.27 11.8 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain CENP-B_dimeris PF09026.10 GAX15256.1 - 5.9 7.3 19.3 3 8.3 10.2 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CPSF73-100_C PF11718.8 GAX15257.1 - 7.8e-32 110.6 0.0 1.2e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 GAX15257.1 - 3.3e-30 104.6 0.0 2e-29 102.1 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 GAX15257.1 - 3.8e-17 62.4 0.0 1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX15257.1 - 8e-15 55.4 0.3 1.8e-14 54.3 0.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 GAX15257.1 - 1.4e-13 50.6 0.0 3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 GAX15257.1 - 2.1e-08 34.0 0.1 6.7e-08 32.3 0.1 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAX15257.1 - 4.1e-06 26.8 0.1 1.1e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GAX15257.1 - 0.00011 21.6 0.0 0.00025 20.3 0.0 1.6 1 0 0 1 1 1 1 Putative beta-lactamase-like family Gemin6 PF06372.12 GAX15257.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Gemin6 protein COX15-CtaA PF02628.15 GAX15259.1 - 4.5e-96 321.7 10.7 5.3e-96 321.5 10.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Amidinotransf PF02274.17 GAX15260.1 - 4.6e-10 39.1 0.0 1.6e-09 37.3 0.0 1.6 1 1 1 2 2 2 1 Amidinotransferase Med4 PF10018.9 GAX15261.1 - 2e-06 27.7 6.4 5.3e-06 26.2 6.4 1.8 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Ribosomal_S30AE PF02482.19 GAX15262.1 - 0.083 13.7 0.9 1.2 10.0 0.1 2.7 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein Choline_transpo PF04515.12 GAX15263.1 - 7.6e-68 229.1 22.7 7.6e-68 229.1 22.7 2.9 1 1 1 3 3 3 2 Plasma-membrane choline transporter DUF4999 PF16390.5 GAX15263.1 - 0.055 13.7 0.4 2.1 8.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function Myosin_head PF00063.21 GAX15266.1 - 2.7e-222 739.7 0.0 3.6e-222 739.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Ank PF00023.30 GAX15266.1 - 2.2e-22 78.5 13.9 4.6e-05 23.7 0.1 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.7 GAX15266.1 - 1.3e-20 73.7 3.0 8.3e-09 35.9 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX15266.1 - 1.4e-18 66.7 4.6 8.8e-06 25.9 0.1 5.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX15266.1 - 3.1e-16 59.5 7.3 0.027 15.0 0.0 6.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX15266.1 - 1.3e-11 43.6 8.6 0.25 12.0 0.0 7.4 7 0 0 7 7 6 3 Ankyrin repeat FYVE PF01363.21 GAX15266.1 - 6e-06 26.3 9.4 1.3e-05 25.2 9.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 GAX15266.1 - 2.1e-05 23.9 31.3 0.071 12.9 0.3 6.7 6 0 0 6 6 6 2 IQ calmodulin-binding motif AAA_16 PF13191.6 GAX15266.1 - 0.0052 17.2 6.3 0.047 14.1 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain Helo_like_N PF17111.5 GAX15266.1 - 0.012 15.0 1.4 0.031 13.7 1.4 1.7 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Sigma54_activat PF00158.26 GAX15266.1 - 0.037 13.7 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0242 PF06785.11 GAX15266.1 - 0.045 13.9 7.3 0.1 12.7 7.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_22 PF13401.6 GAX15266.1 - 0.076 13.3 0.7 0.32 11.3 0.0 2.5 2 0 0 2 2 1 0 AAA domain TMF_TATA_bd PF12325.8 GAX15266.1 - 0.17 12.1 18.5 0.77 10.0 7.4 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 GAX15266.1 - 0.22 12.0 14.6 0.7 10.3 14.6 1.9 1 0 0 1 1 1 0 Fez1 IBR PF01485.21 GAX15266.1 - 0.28 11.5 6.8 1.3 9.3 5.3 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain ABC_tran PF00005.27 GAX15266.1 - 0.32 11.5 1.3 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 ABC transporter HIP1_clath_bdg PF16515.5 GAX15266.1 - 0.59 10.8 18.9 0.081 13.5 6.9 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FapA PF03961.13 GAX15266.1 - 0.91 8.1 6.1 1.3 7.6 5.4 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A CorA PF01544.18 GAX15266.1 - 1.1 8.5 3.9 3 7.1 3.9 1.8 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GAS PF13851.6 GAX15266.1 - 1.1 8.6 17.2 0.32 10.3 12.4 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rx_N PF18052.1 GAX15266.1 - 1.4 9.3 7.6 3 8.2 0.2 2.7 2 0 0 2 2 2 0 Rx N-terminal domain MDMPI_N PF11716.8 GAX15266.1 - 1.5 9.5 0.0 1.5 9.5 0.0 3.2 3 1 0 3 3 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain FYVE_2 PF02318.16 GAX15266.1 - 1.8 8.8 13.0 0.031 14.5 3.9 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.29 GAX15266.1 - 4.6 7.2 11.6 15 5.6 11.6 1.9 1 0 0 1 1 1 0 PHD-finger PhyH PF05721.13 GAX15267.1 - 3.5e-14 53.6 0.1 6.1e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAX15267.1 - 0.0002 20.3 0.3 0.32 9.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Sec7 PF01369.20 GAX15268.1 - 2e-54 184.1 0.0 8.6e-54 182.0 0.0 2.0 2 0 0 2 2 2 1 Sec7 domain IBN_N PF03810.19 GAX15268.1 - 0.0082 16.0 0.0 0.029 14.3 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec7_N PF12783.7 GAX15268.1 - 0.061 13.2 0.1 0.061 13.2 0.1 3.7 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal STN1_2 PF09170.10 GAX15268.1 - 0.082 13.1 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 SMC_N PF02463.19 GAX15269.1 - 9.7e-46 156.0 69.1 3.3e-45 154.2 69.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAX15269.1 - 2.8e-31 108.2 0.1 1.1e-29 103.1 0.1 3.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 GAX15269.1 - 4.7e-14 52.9 0.0 4.7e-14 52.9 0.0 5.1 2 2 2 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 GAX15269.1 - 4.2e-13 49.8 0.1 7.7e-08 32.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX15269.1 - 4.6e-07 29.5 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAX15269.1 - 0.012 15.8 0.2 0.18 12.1 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 GAX15269.1 - 1.5 9.2 137.9 1.6 9.2 66.5 7.4 3 2 0 3 3 3 0 AAA domain UPF0227 PF05728.12 GAX15269.1 - 4.1 7.3 9.6 0.34 10.8 2.9 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) GTP_EFTU PF00009.27 GAX15269.1 - 5.9 6.4 17.7 1.1 8.8 0.0 5.0 5 1 0 5 5 5 0 Elongation factor Tu GTP binding domain IF4E PF01652.18 GAX15270.1 - 5.3e-51 172.6 0.0 7.1e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CwfJ_C_1 PF04677.15 GAX15271.1 - 3.1e-22 78.7 0.1 7.3e-22 77.5 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 GAX15271.1 - 2.3e-08 33.7 0.0 0.0013 18.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 GAX15271.1 - 2.3e-06 28.4 0.0 6.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Trs65 PF12735.7 GAX15273.1 - 2.8e-10 40.1 0.1 8.9e-10 38.5 0.1 1.7 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 CAP PF00188.26 GAX15274.1 - 0.049 14.5 0.3 2.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Cysteine-rich secretory protein family PAP_central PF04928.17 GAX15274.1 - 0.062 12.3 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Poly(A) polymerase central domain mit_SMPDase PF14724.6 GAX15275.1 - 5.2e-08 31.4 0.3 0.0054 14.8 0.5 3.1 2 1 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase PDZ PF00595.24 GAX15276.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PRP3 PF08572.10 GAX15276.1 - 0.042 13.6 1.5 0.06 13.1 1.5 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) PDZ_6 PF17820.1 GAX15276.1 - 0.094 12.6 0.1 2.8 7.8 0.0 2.5 3 0 0 3 3 3 0 PDZ domain PDZ_2 PF13180.6 GAX15276.1 - 0.096 13.0 0.0 0.26 11.6 0.0 1.8 1 1 0 1 1 1 0 PDZ domain DUF4538 PF15061.6 GAX15276.1 - 2 8.2 3.7 1 9.1 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) PTR2 PF00854.21 GAX15278.1 - 1.6e-85 287.3 3.7 2.1e-85 286.9 3.7 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 GAX15278.1 - 8.5e-09 34.8 23.2 1.2e-05 24.4 1.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Trypsin_2 PF13365.6 GAX15279.1 - 2.4e-14 54.5 0.2 6.1e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain COR PF16095.5 GAX15279.1 - 1.4e-06 28.3 0.0 4e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 GAX15279.1 - 0.0014 18.8 0.0 0.0056 16.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Trypsin PF00089.26 GAX15279.1 - 0.01 15.6 0.2 0.85 9.4 0.0 3.2 3 0 0 3 3 3 0 Trypsin Pkinase PF00069.25 GAX15280.1 - 2.5e-46 158.2 0.0 4e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15280.1 - 9.3e-21 74.3 0.0 3.9e-20 72.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX15280.1 - 3.5e-08 32.7 0.1 4.6e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX15280.1 - 9.2e-06 25.1 0.6 1.6e-05 24.4 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAX15280.1 - 0.00017 21.3 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAX15280.1 - 0.0058 16.6 0.0 0.02 14.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX15280.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Glyco_transf_22 PF03901.17 GAX15281.1 - 2.9e-63 214.6 22.5 3.8e-63 214.1 22.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family RabGAP-TBC PF00566.18 GAX15282.1 - 2.6e-52 177.6 0.8 4.1e-52 176.9 0.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAM220 PF15487.6 GAX15282.1 - 0.012 15.3 3.2 0.021 14.5 3.2 1.3 1 0 0 1 1 1 0 FAM220 family MFS_1 PF07690.16 GAX15283.1 - 1.6e-21 76.7 34.7 1.6e-21 76.7 34.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAX15283.1 - 0.12 10.6 5.0 0.052 11.8 2.1 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UMP1 PF05348.11 GAX15284.1 - 1.3e-16 60.8 0.0 1.6e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Aminotran_1_2 PF00155.21 GAX15285.1 - 7.3e-45 153.7 0.0 8.9e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAX15285.1 - 0.0014 18.0 0.0 0.0071 15.7 0.0 2.0 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_C1 PF00112.23 GAX15286.1 - 1.8e-66 224.4 0.1 2.3e-66 224.0 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX15286.1 - 1.2e-13 51.3 0.6 1.8e-13 50.7 0.6 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAX15286.1 - 0.00032 19.6 0.0 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF1894 PF08979.11 GAX15286.1 - 0.024 15.0 0.0 0.073 13.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) Lin0512_fam PF09585.10 GAX15287.1 - 7.5e-10 38.9 0.0 6.4e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) OB_Dis3 PF17849.1 GAX15287.1 - 0.15 12.1 0.0 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) Lactamase_B PF00753.27 GAX15288.1 - 2.9e-12 47.0 2.9 2.5e-10 40.7 2.9 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAX15288.1 - 0.14 11.6 0.2 0.24 10.9 0.2 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 GAX15289.1 - 1.5e-56 191.8 0.0 1.9e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX15289.1 - 2.5e-27 95.3 0.0 4.4e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX15289.1 - 1.6e-16 60.6 2.3 5.1e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX15289.1 - 5e-09 35.9 0.0 4.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX15289.1 - 3.3e-06 26.5 4.0 0.00016 20.9 4.8 2.7 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 GAX15289.1 - 5.4e-06 25.7 0.0 9.6e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAX15289.1 - 0.0004 19.8 0.3 0.0012 18.2 0.2 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAX15289.1 - 0.0013 17.5 2.5 0.012 14.4 1.0 2.9 3 1 1 4 4 4 1 HI0933-like protein FAD_oxidored PF12831.7 GAX15289.1 - 0.0018 17.7 3.7 0.0027 17.1 3.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAX15289.1 - 0.019 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 GAX15289.1 - 0.11 12.0 0.9 0.26 10.8 0.9 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX15289.1 - 0.14 12.2 0.8 7 6.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAX15289.1 - 1 9.6 5.6 0.13 12.5 0.6 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SART-1 PF03343.13 GAX15290.1 - 1.2e-62 212.4 55.0 5.9e-56 190.3 53.0 3.1 2 1 0 2 2 2 2 SART-1 family HATPase_c PF02518.26 GAX15292.1 - 7.9e-21 74.7 0.0 1.5e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX15292.1 - 9.9e-11 41.8 0.1 2.6e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX15292.1 - 8.4e-08 32.1 1.0 1.8e-07 31.0 0.2 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE PF03924.13 GAX15292.1 - 0.00084 19.3 0.0 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 CHASE domain Amnionless PF14828.6 GAX15292.1 - 0.014 14.2 0.6 0.023 13.6 0.1 1.5 2 0 0 2 2 2 0 Amnionless Ac76 PF05814.11 GAX15292.1 - 0.1 12.7 1.4 5.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) DUF5305 PF17231.2 GAX15292.1 - 0.15 11.4 0.2 18 4.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DHHC PF01529.20 GAX15292.1 - 0.79 9.8 2.7 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase LapA_dom PF06305.11 GAX15292.1 - 1.6 8.6 4.2 20 5.1 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF5326 PF17260.2 GAX15292.1 - 6.4 7.0 8.6 2.2 8.5 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5326) FeThRed_B PF02943.15 GAX15293.1 - 0.013 15.5 0.6 0.029 14.4 0.1 1.8 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain Ank_2 PF12796.7 GAX15295.1 - 2.8e-18 66.3 6.5 5.5e-10 39.7 0.7 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX15295.1 - 9.3e-11 42.0 0.7 1.2e-06 28.9 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX15295.1 - 2.5e-07 30.8 1.1 1.8e-05 24.9 0.5 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 GAX15295.1 - 3.2e-07 30.1 0.1 2.1e-06 27.6 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GAX15295.1 - 1.1e-05 25.6 0.4 4.6e-05 23.6 0.2 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX15296.1 - 2.5e-12 47.0 0.0 1.3e-06 28.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX15296.1 - 9.3e-10 39.0 0.0 3.6e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX15296.1 - 3.7e-08 33.0 0.0 1.8e-06 27.8 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAX15296.1 - 1.8e-07 31.3 0.0 7.3e-06 26.2 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 GAX15296.1 - 6.2e-05 23.2 0.0 0.00029 21.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) HSF_DNA-bind PF00447.17 GAX15297.1 - 2.4e-05 24.9 0.0 3.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase_Tyr PF07714.17 GAX15298.1 - 3.3e-29 102.0 0.0 2.4e-28 99.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX15298.1 - 1.5e-28 99.9 0.0 7.1e-28 97.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX15298.1 - 0.0064 15.3 0.0 0.0083 14.9 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase DnaJ PF00226.31 GAX15299.1 - 1.3e-10 41.2 0.2 3.8e-09 36.5 0.0 2.4 2 1 0 2 2 2 2 DnaJ domain CBM_6 PF03422.15 GAX15300.1 - 2.2e-31 108.7 0.0 3.7e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX15300.1 - 7.5e-11 42.1 0.0 7.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX15300.1 - 1.7e-05 25.0 0.1 0.033 14.4 0.1 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) PRNT PF15174.6 GAX15302.1 - 0.041 13.9 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Prion-related protein testis-specific Globin PF00042.22 GAX15303.1 - 1.5e-12 48.0 0.0 2.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Globin DivIC PF04977.15 GAX15304.1 - 0.0022 17.7 1.3 0.0022 17.7 1.3 2.2 2 0 0 2 2 2 1 Septum formation initiator DUF3972 PF13118.6 GAX15304.1 - 0.0032 17.9 0.1 0.0056 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) TolA_bind_tri PF16331.5 GAX15304.1 - 0.0033 17.5 2.5 0.0033 17.5 2.5 2.0 2 1 0 2 2 2 1 TolA binding protein trimerisation HALZ PF02183.18 GAX15304.1 - 0.0083 16.3 1.1 0.02 15.1 1.1 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper ZapB PF06005.12 GAX15304.1 - 0.024 15.1 5.4 0.024 15.1 5.4 2.3 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 GAX15304.1 - 0.043 13.9 11.2 0.11 12.6 11.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 GAX15304.1 - 0.063 13.9 4.1 0.063 13.9 2.6 1.7 1 1 1 2 2 2 0 Initiation control protein YabA DUF5320 PF17253.2 GAX15304.1 - 0.11 13.6 0.7 0.2 12.7 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF948 PF06103.11 GAX15304.1 - 0.14 12.4 0.2 0.24 11.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) bZIP_2 PF07716.15 GAX15304.1 - 0.28 11.3 9.8 0.81 9.8 9.6 2.0 1 1 0 1 1 1 0 Basic region leucine zipper Cnn_1N PF07989.11 GAX15304.1 - 0.35 11.0 3.7 0.4 10.9 2.5 1.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 GAX15304.1 - 0.38 11.2 1.2 0.73 10.3 1.2 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 GAX15304.1 - 0.44 9.6 10.7 0.26 10.3 9.0 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 GAX15304.1 - 0.82 9.9 5.6 0.65 10.3 3.8 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.6 GAX15304.1 - 1.5 9.2 7.0 0.58 10.5 0.4 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 GrpE PF01025.19 GAX15304.1 - 1.7 8.2 6.4 3.4 7.3 6.4 1.6 1 1 0 1 1 1 0 GrpE Bap31_Bap29_C PF18035.1 GAX15304.1 - 2.2 8.4 5.8 3.7 7.6 2.9 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain UPF0242 PF06785.11 GAX15304.1 - 4 7.5 8.4 9.8 6.2 8.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 GAX15305.1 - 2.5e-06 27.5 9.5 2.5e-06 27.5 9.5 2.2 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.15 GAX15305.1 - 0.012 15.3 3.3 0.019 14.7 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 GAX15305.1 - 0.016 15.4 0.2 0.035 14.3 0.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF5595 PF18077.1 GAX15305.1 - 0.091 12.8 1.7 0.21 11.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) FlaC_arch PF05377.11 GAX15305.1 - 0.14 12.5 1.7 0.31 11.4 1.7 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 GAX15305.1 - 0.25 11.5 9.6 0.88 9.7 9.6 2.0 1 0 0 1 1 1 0 Basic region leucine zipper Cep57_MT_bd PF06657.13 GAX15305.1 - 1.1 9.8 8.6 1.8 9.1 0.7 3.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 PK PF00224.21 GAX15306.1 - 5.6e-144 479.3 4.1 1.1e-143 478.3 4.1 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAX15306.1 - 1.8e-25 89.5 1.5 1.8e-25 89.5 1.5 2.5 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAX15306.1 - 0.0039 16.4 0.7 0.016 14.4 0.3 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family RRP36 PF06102.12 GAX15307.1 - 8.4e-30 103.9 13.7 8.4e-30 103.9 13.7 2.4 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 CsgA PF17334.2 GAX15307.1 - 0.034 14.9 0.0 0.034 14.9 0.0 3.0 4 0 0 4 4 4 0 Minor curli fiber component A ArfGap PF01412.18 GAX15308.1 - 1.3e-14 54.2 2.3 1.3e-14 54.2 2.3 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Zn_Tnp_IS1595 PF12760.7 GAX15308.1 - 0.26 11.3 3.3 0.48 10.4 3.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain YacG PF03884.14 GAX15308.1 - 2.5 7.9 5.2 2.4 8.0 0.1 2.6 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG GCFC PF07842.12 GAX15311.1 - 1.7e-10 41.0 9.9 1.7e-10 41.0 9.9 2.7 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 GAX15311.1 - 5.4e-10 39.6 15.5 1.7e-09 38.0 14.5 2.4 1 1 1 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.23 GAX15311.1 - 8.3e-09 35.2 1.9 2.2e-08 33.8 1.9 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAX15311.1 - 0.00019 21.5 1.7 0.00085 19.4 1.3 2.3 2 0 0 2 2 2 1 G-patch domain BAR_3_WASP_bdg PF10456.9 GAX15311.1 - 0.0061 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF948 PF06103.11 GAX15311.1 - 0.038 14.2 0.1 0.21 11.8 0.1 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HWE_HK PF07536.14 GAX15311.1 - 0.087 13.5 1.8 1.7 9.4 0.0 3.4 3 0 0 3 3 3 0 HWE histidine kinase MAS20 PF02064.15 GAX15311.1 - 0.88 9.7 5.0 2.8 8.0 2.8 2.9 3 0 0 3 3 3 0 MAS20 protein import receptor Abhydrolase_1 PF00561.20 GAX15312.1 - 6.3e-22 78.4 0.0 7.4e-19 68.4 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX15312.1 - 2.7e-15 56.3 0.0 2.2e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX15312.1 - 3.8e-14 53.8 1.3 5.3e-14 53.3 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 GAX15312.1 - 0.0013 18.0 0.1 0.62 9.2 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF2920) Abhydrolase_5 PF12695.7 GAX15312.1 - 0.0066 16.2 0.0 0.024 14.4 0.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GAX15312.1 - 0.026 14.7 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 GAX15312.1 - 0.026 14.3 0.2 1.4 8.6 0.0 3.2 3 1 0 4 4 4 0 Phospholipase/Carboxylesterase Esterase PF00756.20 GAX15312.1 - 0.14 11.7 0.7 0.36 10.4 0.0 1.9 3 0 0 3 3 3 0 Putative esterase IF4E PF01652.18 GAX15313.1 - 1.1e-26 93.5 0.0 1.4e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E BET PF17035.5 GAX15314.1 - 1.2e-17 63.8 0.6 1.2e-17 63.8 0.6 2.1 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 GAX15314.1 - 1.2e-12 47.8 0.0 2.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain KH_1 PF00013.29 GAX15314.1 - 0.16 11.8 4.2 0.072 12.9 0.4 2.3 2 0 0 2 2 2 0 KH domain EF-hand_1 PF00036.32 GAX15315.1 - 7.4e-37 122.2 14.8 5.2e-10 38.2 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAX15315.1 - 3.1e-32 110.8 5.6 4.4e-17 62.3 0.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX15315.1 - 7.5e-28 94.1 9.8 1.1e-08 34.3 0.2 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAX15315.1 - 2.1e-25 88.3 12.2 5.7e-16 58.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAX15315.1 - 6.8e-25 85.4 12.1 8.1e-08 31.4 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAX15315.1 - 9.8e-16 57.8 0.1 4.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAX15315.1 - 3.2e-09 37.1 0.5 0.001 19.4 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 GAX15315.1 - 2.1e-05 25.3 0.0 0.0042 17.9 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 GAX15315.1 - 2.9e-05 24.0 0.1 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) p25-alpha PF05517.12 GAX15315.1 - 0.00011 22.4 0.0 0.014 15.5 0.0 2.6 1 1 1 2 2 2 1 p25-alpha Dockerin_1 PF00404.18 GAX15315.1 - 0.00018 21.6 3.3 0.34 11.1 0.0 3.4 2 1 2 4 4 4 2 Dockerin type I domain EF-hand_4 PF12763.7 GAX15315.1 - 0.00059 19.8 7.4 0.92 9.5 0.1 3.8 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand DUF1707 PF08044.11 GAX15315.1 - 0.0021 18.1 0.8 1.8 8.7 0.2 3.6 2 2 1 3 3 3 1 Domain of unknown function (DUF1707) DUF3349 PF11829.8 GAX15315.1 - 0.004 17.9 0.3 2.7 8.8 0.1 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF3349) TerB PF05099.13 GAX15315.1 - 0.0099 15.8 0.6 0.11 12.4 0.0 2.3 1 1 2 3 3 3 1 Tellurite resistance protein TerB DUF533 PF04391.12 GAX15315.1 - 0.02 14.5 1.4 3.3 7.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF533) Caleosin PF05042.13 GAX15315.1 - 0.036 14.0 0.1 2.3 8.1 0.0 2.8 1 1 1 3 3 3 0 Caleosin related protein GlutR_dimer PF00745.20 GAX15315.1 - 0.042 14.3 0.4 4.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF853 PF05872.12 GAX15315.1 - 0.058 12.0 1.3 4.1 5.9 0.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF327 PF03885.13 GAX15315.1 - 0.058 13.4 1.4 9.8 6.1 0.1 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF327) SRP54_N PF02881.19 GAX15315.1 - 0.073 13.3 3.7 9.2 6.6 0.3 3.1 2 2 1 3 3 3 0 SRP54-type protein, helical bundle domain DUF4455 PF14643.6 GAX15315.1 - 0.11 11.1 1.2 2.6 6.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) Bile_Hydr_Trans PF04775.14 GAX15315.1 - 0.15 12.2 0.0 3.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region DUF4191 PF13829.6 GAX15315.1 - 0.16 11.3 0.0 16 4.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) S_100 PF01023.19 GAX15315.1 - 1.4 8.7 6.2 21 4.9 0.0 4.1 6 0 0 6 6 6 0 S-100/ICaBP type calcium binding domain ThiF PF00899.21 GAX15316.1 - 1.6e-35 122.7 0.1 2.4e-35 122.1 0.1 1.2 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 GAX15316.1 - 0.00021 21.7 0.0 0.00049 20.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 GAX15316.1 - 0.0031 17.1 0.2 0.0057 16.2 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HALZ PF02183.18 GAX15317.1 - 0.036 14.3 0.5 0.088 13.1 0.1 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 GAX15317.1 - 0.084 12.7 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 GAX15317.1 - 0.18 11.9 0.6 0.43 10.7 0.6 1.7 1 0 0 1 1 1 0 Basic region leucine zipper PK PF00224.21 GAX15318.1 - 6.2e-144 479.2 4.1 1.2e-143 478.3 4.1 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAX15318.1 - 5.3e-26 91.2 4.0 5.9e-26 91.0 1.6 2.4 2 1 1 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAX15318.1 - 0.013 14.7 0.7 0.055 12.6 0.1 2.0 1 1 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family RRP36 PF06102.12 GAX15319.1 - 1.2e-29 103.4 13.0 1.2e-29 103.4 13.0 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 CsgA PF17334.2 GAX15319.1 - 0.00091 19.9 0.3 0.0073 17.0 0.0 2.6 2 0 0 2 2 2 1 Minor curli fiber component A ArfGap PF01412.18 GAX15320.1 - 1.1e-14 54.4 2.0 1.1e-14 54.4 2.0 2.2 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf Zn_Tnp_IS1595 PF12760.7 GAX15320.1 - 0.38 10.8 3.8 0.69 9.9 3.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain YacG PF03884.14 GAX15320.1 - 3.1 7.6 5.9 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG TssN PF17555.2 GAX15321.1 - 0.076 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN KIP1 PF07765.12 GAX15321.1 - 0.14 12.3 1.7 4.2 7.6 0.4 2.9 3 0 0 3 3 3 0 KIP1-like protein GCFC PF07842.12 GAX15322.1 - 7.1e-12 45.5 7.7 7.1e-12 45.5 7.7 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 GAX15322.1 - 5.7e-09 36.3 8.4 2.2e-08 34.4 8.4 2.1 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal G-patch PF01585.23 GAX15322.1 - 3.1e-08 33.4 1.8 7.2e-08 32.2 1.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAX15322.1 - 0.00054 20.0 3.3 0.0019 18.3 1.6 2.7 2 0 0 2 2 2 1 G-patch domain DUF948 PF06103.11 GAX15322.1 - 0.0044 17.3 0.1 0.016 15.4 0.1 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Myb_DNA-bind_5 PF13873.6 GAX15322.1 - 0.21 11.7 2.6 7.3 6.7 0.4 2.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain UCH PF00443.29 GAX15322.1 - 1.7 8.1 5.4 1.9 7.9 0.0 2.9 3 1 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_1 PF00561.20 GAX15323.1 - 1.5e-21 77.2 0.0 1.2e-18 67.8 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX15323.1 - 1.7e-18 68.0 0.1 2.3e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX15323.1 - 1.2e-16 60.8 0.0 1.3e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 GAX15323.1 - 0.00029 20.2 0.1 0.46 9.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2920) Thioesterase PF00975.20 GAX15323.1 - 0.00051 20.2 0.1 0.00072 19.7 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 GAX15323.1 - 0.017 14.9 0.0 0.063 13.0 0.1 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 GAX15323.1 - 0.073 12.7 0.0 0.27 10.8 0.0 1.9 2 1 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 GAX15323.1 - 0.098 12.4 0.0 8.8 6.1 0.0 2.8 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase BET PF17035.5 GAX15324.1 - 1.3e-17 63.7 0.6 1.3e-17 63.7 0.6 2.1 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 GAX15324.1 - 8.9e-13 48.1 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain KH_1 PF00013.29 GAX15324.1 - 0.15 11.9 4.5 0.061 13.2 0.4 2.4 2 0 0 2 2 2 0 KH domain ThiF PF00899.21 GAX15325.1 - 4.5e-35 121.2 0.1 7.5e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 GAX15325.1 - 0.00031 21.1 0.0 0.00066 20.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 GAX15325.1 - 0.003 17.2 0.2 0.0057 16.3 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Chloroa_b-bind PF00504.21 GAX15326.1 - 1.7e-20 74.2 0.0 2.2e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF572 PF04502.13 GAX15327.1 - 3e-22 79.7 19.5 1e-20 74.7 19.5 2.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) Cytochrome_C7 PF14522.6 GAX15327.1 - 3.7 7.6 7.2 2.3 8.3 3.1 2.6 2 1 1 3 3 3 0 Cytochrome c7 and related cytochrome c S1 PF00575.23 GAX15328.1 - 1.5e-11 44.5 0.0 3.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Rsd_AlgQ PF04353.13 GAX15329.1 - 0.053 13.5 0.1 0.093 12.7 0.1 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Mpv17_PMP22 PF04117.12 GAX15330.1 - 1.2e-12 47.9 0.2 2.1e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pro_isomerase PF00160.21 GAX15331.1 - 1.1e-13 51.8 0.0 1.5e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_12 PF13424.6 GAX15332.1 - 0.0065 16.7 0.9 7.4 6.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15332.1 - 0.018 14.8 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3826 PF12875.7 GAX15332.1 - 0.09 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) DUF1548 PF07579.11 GAX15332.1 - 0.13 12.5 0.1 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) zf-C3HC4_2 PF13923.6 GAX15333.1 - 3.8e-09 36.2 8.2 6.5e-08 32.3 8.2 2.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX15333.1 - 1.2e-08 34.8 7.8 3.4e-08 33.4 7.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX15333.1 - 4.7e-08 32.8 6.8 4.7e-08 32.8 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX15333.1 - 8.4e-08 32.0 9.0 8.4e-08 32.0 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX15333.1 - 4.6e-07 29.7 8.0 4.6e-07 29.7 8.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAX15333.1 - 1.9e-06 28.1 8.3 1.9e-06 28.1 8.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAX15333.1 - 1.1e-05 25.5 8.6 3.5e-05 23.9 8.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAX15333.1 - 0.00012 21.9 7.2 0.00013 21.8 5.2 2.1 2 1 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 GAX15333.1 - 0.00016 21.4 6.2 0.00016 21.4 6.2 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 SAP PF02037.27 GAX15333.1 - 0.00065 19.4 0.4 0.00065 19.4 0.4 1.9 2 0 0 2 2 1 1 SAP domain zf-RING_10 PF16685.5 GAX15333.1 - 0.0012 19.0 5.5 0.0012 19.0 5.5 2.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RanBP PF00641.18 GAX15333.1 - 0.0028 16.9 5.5 0.0028 16.9 5.5 3.1 5 0 0 5 5 4 1 Zn-finger in Ran binding protein and others CLTH PF10607.9 GAX15333.1 - 0.046 13.6 0.2 0.16 11.8 0.2 1.8 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain DUF2225 PF09986.9 GAX15333.1 - 0.046 13.4 4.1 0.048 13.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Nse PF11789.8 GAX15333.1 - 0.064 13.1 9.3 0.06 13.2 6.5 2.5 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 GAX15333.1 - 0.76 10.1 12.2 0.078 13.3 6.7 2.4 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAX15333.1 - 4.2 7.5 8.3 0.23 11.6 2.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spt4 PF06093.13 GAX15333.1 - 6.2 7.0 7.7 0.85 9.8 0.9 2.7 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger RNase_PH PF01138.21 GAX15334.1 - 2.1e-08 34.8 2.1 2.4e-08 34.6 0.0 2.2 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX15334.1 - 0.0028 17.6 0.0 0.008 16.2 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MFS_1 PF07690.16 GAX15336.1 - 3.4e-27 95.3 44.2 3.4e-27 95.3 44.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAX15337.1 - 1.8e-28 99.5 35.1 1.8e-28 99.5 35.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 GAX15337.1 - 0.086 13.0 0.7 0.44 10.7 0.0 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 cNMP_binding PF00027.29 GAX15338.1 - 0.00076 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain A_deaminase PF00962.22 GAX15340.1 - 2.1e-33 116.0 0.1 4.7e-32 111.6 0.1 2.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase SET PF00856.28 GAX15341.1 - 0.0012 19.2 0.0 0.022 15.1 0.0 2.7 1 1 1 2 2 2 1 SET domain SAF PF08666.12 GAX15341.1 - 0.052 14.2 0.0 20 5.9 0.0 2.6 2 0 0 2 2 2 0 SAF domain SRP54 PF00448.22 GAX15342.1 - 2.3e-64 216.7 0.1 4.1e-64 215.8 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GAX15342.1 - 2.8e-06 27.5 0.1 8.5e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 GAX15342.1 - 1.3e-05 25.6 0.3 4e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 GAX15342.1 - 0.00046 20.0 0.1 0.00089 19.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAX15342.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX15342.1 - 0.006 16.9 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAX15342.1 - 0.007 16.3 2.6 0.13 12.1 0.2 2.9 2 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 GAX15342.1 - 0.016 15.5 2.1 0.044 14.0 0.1 2.6 2 2 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAX15342.1 - 0.023 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 GAX15342.1 - 0.024 15.1 1.7 0.41 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Helicase_RecD PF05127.14 GAX15342.1 - 0.026 14.4 0.3 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 Helicase AAA_28 PF13521.6 GAX15342.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAX15342.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 GAX15342.1 - 0.077 13.0 0.2 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAX15342.1 - 0.084 12.9 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.14 GAX15342.1 - 0.099 10.5 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Helicase ABC_tran PF00005.27 GAX15342.1 - 0.1 13.1 1.0 0.16 12.5 0.2 1.9 2 1 0 2 2 1 0 ABC transporter CbiA PF01656.23 GAX15342.1 - 0.1 12.6 0.3 0.69 10.0 0.1 2.4 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ORC3_N PF07034.11 GAX15342.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus AAA_31 PF13614.6 GAX15342.1 - 0.14 12.1 0.4 2.6 7.9 0.1 2.3 1 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 GAX15342.1 - 0.23 11.2 0.9 7.1 6.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 GAX15342.1 - 0.3 11.1 2.6 1.1 9.3 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain adh_short PF00106.25 GAX15343.1 - 3.9e-24 85.2 0.0 5.7e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX15343.1 - 7.6e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX15343.1 - 0.0032 17.4 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAX15343.1 - 0.0035 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 GAX15343.1 - 0.014 14.8 0.3 0.11 11.9 0.3 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GAX15343.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gp_dh_C PF02800.20 GAX15346.1 - 2.5e-66 222.2 0.0 4e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX15346.1 - 4.5e-30 104.0 0.0 1e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Macoilin PF09726.9 GAX15347.1 - 0.0003 19.5 8.5 0.0003 19.5 8.5 2.4 1 1 1 2 2 1 1 Macoilin family PSD1 PF07587.11 GAX15347.1 - 0.002 17.7 3.2 0.0038 16.7 3.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1553) Tropomyosin_1 PF12718.7 GAX15347.1 - 0.012 15.8 4.8 0.012 15.8 4.8 1.8 2 0 0 2 2 1 0 Tropomyosin like DnaJ PF00226.31 GAX15347.1 - 0.06 13.5 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 DnaJ domain Cob_adeno_trans PF01923.18 GAX15347.1 - 0.067 13.3 1.4 0.21 11.7 1.2 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Syntaxin-6_N PF09177.11 GAX15347.1 - 0.1 13.2 3.7 0.77 10.3 3.3 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CLZ PF16526.5 GAX15347.1 - 0.17 12.2 11.7 0.27 11.6 0.9 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LptF_LptG PF03739.14 GAX15347.1 - 0.19 10.5 0.6 0.28 10.0 0.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Lys-AminoMut_A PF09043.11 GAX15347.1 - 0.2 10.0 1.7 0.28 9.6 1.7 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit DUF1978 PF09321.10 GAX15347.1 - 0.87 8.9 10.0 0.32 10.3 6.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1978) Enkurin PF13864.6 GAX15347.1 - 0.98 9.9 7.6 1.2 9.7 5.4 2.2 1 1 1 2 2 2 0 Calmodulin-binding Bcr-Abl_Oligo PF09036.10 GAX15347.1 - 1.3 9.1 5.7 0.83 9.7 0.6 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Fib_alpha PF08702.10 GAX15347.1 - 2.8 8.1 8.4 5.2 7.3 5.8 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PNP_UDP_1 PF01048.20 GAX15348.1 - 3.9e-21 75.4 0.1 4.8e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Hydrolase_6 PF13344.6 GAX15349.1 - 2.4e-26 91.8 0.0 4.8e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX15349.1 - 1.1e-15 57.4 0.0 3.2e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX15349.1 - 1.6e-09 38.4 0.0 1.2e-08 35.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX15349.1 - 4.9e-07 30.0 0.0 0.0058 16.7 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAX15349.1 - 0.0015 18.2 0.1 0.2 11.3 0.0 2.7 2 1 0 3 3 3 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 GAX15349.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DSPc PF00782.20 GAX15350.1 - 2.3e-08 33.9 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX15350.1 - 0.0004 20.0 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AEP1 PF17049.5 GAX15350.1 - 0.077 12.1 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 PTPlike_phytase PF14566.6 GAX15350.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate RIIa PF02197.17 GAX15351.1 - 0.0013 18.4 2.5 12 5.7 0.0 5.1 6 0 0 6 6 6 3 Regulatory subunit of type II PKA R-subunit Alph_Pro_TM PF09608.10 GAX15351.1 - 0.12 12.1 0.1 20 4.9 0.0 2.9 2 2 2 4 4 4 0 Putative transmembrane protein (Alph_Pro_TM) LRR_8 PF13855.6 GAX15352.1 - 8.5e-23 79.9 34.1 6.4e-07 29.0 5.1 6.5 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX15352.1 - 1.2e-19 70.1 35.3 8.4e-05 22.9 1.9 8.5 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX15352.1 - 1.1e-07 31.4 21.3 0.63 10.8 0.0 9.1 8 2 0 8 8 8 4 Leucine Rich Repeat Amidase PF01425.21 GAX15353.1 - 7.2e-93 312.0 1.8 5.8e-71 239.8 0.8 2.5 2 1 0 2 2 2 2 Amidase Ldh_2 PF02615.14 GAX15354.1 - 2e-84 283.6 6.1 2.3e-84 283.4 6.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PCNA_C PF02747.15 GAX15355.1 - 9.7e-51 171.3 0.1 8.9e-50 168.1 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 GAX15355.1 - 1.4e-42 144.4 5.0 2.7e-42 143.5 5.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 GAX15355.1 - 4e-07 29.7 0.2 4.6e-07 29.6 0.2 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 GAX15355.1 - 5.1e-05 22.5 1.6 9.9e-05 21.5 1.6 1.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 FAM198 PF15051.6 GAX15355.1 - 0.13 11.2 0.2 0.18 10.6 0.2 1.2 1 0 0 1 1 1 0 FAM198 protein CRAL_TRIO PF00650.20 GAX15356.1 - 4.6e-14 52.4 0.0 6.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX15356.1 - 0.093 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain NOA36 PF06524.12 GAX15357.1 - 0.71 9.1 10.2 1.4 8.1 10.2 1.4 1 0 0 1 1 1 0 NOA36 protein MRG PF05712.13 GAX15359.1 - 1.6e-18 66.7 2.6 1.3e-17 63.7 0.1 2.5 2 1 1 3 3 3 2 MRG Tudor-knot PF11717.8 GAX15359.1 - 1.2e-09 37.9 0.7 3.1e-09 36.6 0.7 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DnaJ PF00226.31 GAX15361.1 - 8.8e-24 83.4 0.2 2.1e-23 82.2 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 GAX15361.1 - 8.9e-13 48.4 3.5 1.8e-12 47.4 3.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 GAX15361.1 - 3.3e-05 23.7 0.0 0.00012 21.9 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15361.1 - 0.0001 21.9 0.0 0.00063 19.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat RPA_C PF08784.11 GAX15361.1 - 0.026 15.2 1.6 0.077 13.7 1.6 1.8 1 0 0 1 1 1 0 Replication protein A C terminal TPR_19 PF14559.6 GAX15361.1 - 0.098 13.2 0.1 0.5 10.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX15361.1 - 0.13 13.2 0.2 1 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec3_C PF09763.9 GAX15363.1 - 6.6e-25 87.6 6.5 6.1e-19 67.9 0.0 2.9 3 1 0 3 3 3 2 Exocyst complex component Sec3 CCDC53 PF10152.9 GAX15365.1 - 3.3e-28 99.0 43.4 4.7e-05 23.8 0.1 9.9 7 2 1 8 8 8 7 Subunit CCDC53 of WASH complex Peptidase_S8_N PF16361.5 GAX15365.1 - 0.0037 17.8 1.2 0.016 15.7 1.2 2.2 1 0 0 1 1 1 1 N-terminal of Subtilase family Ribosomal_L24e PF01246.20 GAX15365.1 - 0.0065 16.7 2.5 18 5.7 0.0 5.5 6 0 0 6 6 6 1 Ribosomal protein L24e SoxG PF04268.12 GAX15365.1 - 0.011 15.8 0.3 12 6.0 0.0 4.6 4 0 0 4 4 4 0 Sarcosine oxidase, gamma subunit family DUF3334 PF11813.8 GAX15365.1 - 0.071 12.8 6.5 3.8 7.2 0.1 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF3334) IGR PF09597.10 GAX15365.1 - 0.15 12.2 0.1 44 4.3 0.0 4.0 3 0 0 3 3 3 0 IGR protein motif Toprim_2 PF13155.6 GAX15365.1 - 0.63 10.5 3.1 2.2 8.8 0.1 3.3 3 0 0 3 3 3 0 Toprim-like Cupin_8 PF13621.6 GAX15366.1 - 2.8e-41 141.9 0.0 4.9e-41 141.1 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX15366.1 - 0.0033 16.9 2.8 0.37 10.2 0.1 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Proho_convert PF12177.8 GAX15366.1 - 0.072 13.1 1.0 8.7 6.4 0.1 2.7 2 0 0 2 2 2 0 Prohormone convertase enzyme Pyr_redox_2 PF07992.14 GAX15367.1 - 1.1e-38 133.2 0.0 1.9e-38 132.4 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX15367.1 - 2.5e-17 63.1 0.0 4.6e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX15367.1 - 6.4e-12 45.9 1.2 2.8e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX15367.1 - 1.3e-09 37.9 0.1 1.3e-09 37.9 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX15367.1 - 1.3e-07 31.1 1.3 2.2e-07 30.3 1.0 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAX15367.1 - 1.5e-06 27.2 0.5 8.1e-06 24.8 1.7 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 GAX15367.1 - 4.8e-05 22.8 2.3 0.00019 20.8 0.6 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX15367.1 - 6.4e-05 22.7 0.7 0.00013 21.7 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX15367.1 - 8.1e-05 22.8 0.7 8.1e-05 22.8 0.7 3.0 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAX15367.1 - 0.00038 19.7 1.1 0.0016 17.6 1.9 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAX15367.1 - 0.0013 18.0 0.7 5.4 6.2 3.3 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX15367.1 - 0.0053 16.0 0.3 0.011 14.9 0.3 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 GAX15367.1 - 0.0071 15.5 0.0 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) SCAB-ABD PF16711.5 GAX15367.1 - 1.5 8.8 4.0 0.77 9.7 0.1 2.5 3 0 0 3 3 2 0 Actin-binding domain of plant-specific actin-binding protein Lycopene_cycl PF05834.12 GAX15367.1 - 2.8 6.9 5.1 0.58 9.1 1.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAX15367.1 - 8.9 5.4 9.1 0.15 11.3 0.6 2.3 3 0 0 3 3 3 0 FAD binding domain UAA PF08449.11 GAX15368.1 - 4.2e-44 151.0 10.8 5.8e-44 150.5 10.8 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 GAX15368.1 - 1.4e-05 24.6 9.1 2e-05 24.1 9.1 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 GAX15368.1 - 0.00027 20.3 1.4 0.00027 20.3 1.4 2.2 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport EamA PF00892.20 GAX15368.1 - 0.027 14.7 0.4 0.027 14.7 0.4 3.1 4 0 0 4 4 4 0 EamA-like transporter family DHHC PF01529.20 GAX15369.1 - 1.5e-30 106.0 11.9 1.5e-30 106.0 11.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Dus PF01207.17 GAX15370.1 - 4.5e-65 219.8 0.0 6e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 GAX15370.1 - 0.00061 19.1 0.0 0.0013 18.0 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase ATP-synt_ab PF00006.25 GAX15371.1 - 8.1e-62 208.6 0.0 1.2e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAX15371.1 - 4.3e-24 84.8 1.4 9.3e-24 83.7 1.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.6 GAX15371.1 - 0.061 13.7 0.5 0.18 12.1 0.2 1.9 2 0 0 2 2 2 0 AAA domain RnfC_N PF13375.6 GAX15371.1 - 0.063 13.2 0.5 0.21 11.5 0.1 2.1 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain NB-ARC PF00931.22 GAX15371.1 - 0.084 12.0 0.4 0.21 10.8 0.2 1.7 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 GAX15371.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 GAX15371.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 GAX15371.1 - 0.27 10.4 0.2 0.44 9.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP-synt_DE_N PF02823.16 GAX15372.1 - 3.2e-14 52.6 0.0 4.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain WD40 PF00400.32 GAX15373.1 - 9.3e-21 73.8 23.1 1.1e-05 26.1 0.3 6.9 7 0 0 7 7 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15373.1 - 1.4e-06 28.5 2.8 3.9 7.8 0.1 5.1 2 1 2 5 5 4 2 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 GAX15373.1 - 1.8e-05 25.1 27.6 1.8e-05 25.1 27.6 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF5046 PF16465.5 GAX15373.1 - 0.015 14.8 0.1 1.2 8.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5046) HALZ PF02183.18 GAX15373.1 - 0.034 14.4 11.9 0.35 11.1 0.8 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3138 PF11336.8 GAX15373.1 - 0.038 12.6 2.2 0.069 11.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) GCN5L1 PF06320.13 GAX15373.1 - 0.082 13.1 19.0 0.78 9.9 7.7 2.8 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) GIT_CC PF16559.5 GAX15373.1 - 0.14 12.0 25.1 1.4 8.9 0.8 5.5 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 GAX15373.1 - 0.3 11.4 17.1 0.26 11.6 0.8 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family Lebercilin PF15619.6 GAX15373.1 - 0.53 9.9 32.5 5.1 6.7 6.8 2.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mating_N PF12731.7 GAX15373.1 - 0.77 9.9 4.9 0.75 9.9 0.3 2.9 3 1 0 3 3 3 0 Mating-type protein beta 1 ApoO PF09769.9 GAX15373.1 - 1.4 8.9 4.6 0.86 9.6 0.5 2.4 2 1 0 2 2 2 0 Apolipoprotein O Fez1 PF06818.15 GAX15373.1 - 1.9 8.9 30.4 1.1 9.6 7.0 2.2 1 1 1 2 2 2 0 Fez1 Mucin2_WxxW PF13330.6 GAX15373.1 - 1.9 9.3 5.4 0.74 10.7 1.5 2.3 2 0 0 2 2 2 0 Mucin-2 protein WxxW repeating region YabA PF06156.13 GAX15373.1 - 2.1 9.0 26.1 0.21 12.2 7.8 4.0 1 1 1 3 3 3 0 Initiation control protein YabA Prp19 PF08606.11 GAX15373.1 - 2.2 8.3 7.1 0.49 10.4 0.1 3.1 3 1 1 4 4 4 0 Prp19/Pso4-like APC_N_CC PF16689.5 GAX15373.1 - 3.6 7.7 13.0 3.1 7.9 0.9 3.8 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain FlaC_arch PF05377.11 GAX15373.1 - 7.6 7.0 15.5 23 5.5 1.1 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Bestrophin PF01062.21 GAX15374.1 - 4.3e-20 72.3 0.2 4.1e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GSAP-16 PF14959.6 GAX15374.1 - 0.0043 16.9 0.9 0.011 15.6 0.9 1.7 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term Kisspeptin PF15152.6 GAX15374.1 - 0.14 13.0 0.2 0.39 11.5 0.2 1.8 1 0 0 1 1 1 0 Kisspeptin IPPT PF01715.17 GAX15375.1 - 5.4e-46 157.2 0.8 2.3e-33 115.9 0.0 2.6 3 0 0 3 3 3 2 IPP transferase IPT PF01745.16 GAX15375.1 - 1.2e-07 31.4 0.3 3.3e-07 29.9 0.0 2.0 3 0 0 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.6 GAX15375.1 - 0.0011 19.1 0.0 0.004 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX15375.1 - 0.022 15.2 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 GAX15375.1 - 0.064 13.7 0.0 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bestrophin PF01062.21 GAX15376.1 - 1.1e-16 61.1 4.1 1.2e-07 31.4 0.5 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Isochorismatase PF00857.20 GAX15377.1 - 3e-40 138.2 0.0 3.7e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Globin PF00042.22 GAX15378.1 - 0.0001 22.8 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 Globin VPS9 PF02204.18 GAX15379.1 - 4.9e-16 58.8 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Mannosyl_trans PF05007.13 GAX15380.1 - 5.2e-56 190.4 17.5 7.6e-56 189.9 17.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) ArnB_C PF18677.1 GAX15382.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain LETM1 PF07766.13 GAX15383.1 - 2.8e-17 62.9 0.2 7.2e-17 61.6 0.2 1.7 1 0 0 1 1 1 1 LETM1-like protein T6SS_VipA PF05591.12 GAX15383.1 - 0.0016 18.3 1.2 0.45 10.3 0.1 3.0 3 0 0 3 3 3 2 Type VI secretion system, VipA, VC_A0107 or Hcp2 Ribosomal_S17_N PF16205.5 GAX15385.1 - 6.9e-31 106.5 0.1 1.4e-30 105.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 GAX15385.1 - 3.7e-27 94.2 0.5 7.4e-27 93.3 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 S1 PF00575.23 GAX15386.1 - 3.3e-31 107.4 0.2 9.1e-17 61.2 0.1 3.4 3 0 0 3 3 3 3 S1 RNA binding domain Erythro-docking PF09277.11 GAX15386.1 - 7.8 6.5 6.5 83 3.2 0.0 3.5 3 0 0 3 3 3 0 Erythronolide synthase, docking bZIP_1 PF00170.21 GAX15388.1 - 1.3e-05 25.2 7.8 1.3e-05 25.2 7.8 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX15388.1 - 0.00097 19.2 5.6 0.00097 19.2 5.6 2.4 1 1 1 2 2 2 1 Basic region leucine zipper TPR_MLP1_2 PF07926.12 GAX15388.1 - 0.016 15.3 10.9 0.023 14.7 10.9 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein JAKMIP_CC3 PF16034.5 GAX15388.1 - 0.018 15.0 6.0 0.024 14.6 6.0 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF2730 PF10805.8 GAX15388.1 - 0.035 14.2 0.5 0.057 13.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) HAUS6_N PF14661.6 GAX15388.1 - 0.17 11.5 4.2 0.22 11.0 4.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF5094 PF17015.5 GAX15388.1 - 0.46 10.6 3.8 0.69 10.0 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DivIC PF04977.15 GAX15388.1 - 1.4 8.8 6.0 1.9 8.3 5.1 1.7 1 1 0 1 1 1 0 Septum formation initiator Beach PF02138.18 GAX15390.1 - 4.8e-109 364.0 0.0 7.2e-109 363.4 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAX15390.1 - 4.7e-09 36.3 0.0 1.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH IRK_C PF17655.1 GAX15391.1 - 2.9e-09 36.8 0.1 0.0035 17.0 0.0 2.7 2 1 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 GAX15391.1 - 0.00013 21.8 1.5 0.013 15.3 0.0 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain zf-C2H2_4 PF13894.6 GAX15391.1 - 0.0081 16.9 0.5 0.036 14.9 0.5 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 GAX15391.1 - 0.085 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 GAX15391.1 - 0.13 12.1 0.0 0.4 10.6 0.0 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 GAX15391.1 - 0.16 12.5 0.4 0.59 10.7 0.4 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type RrnaAD PF00398.20 GAX15392.1 - 1.1e-38 132.9 0.2 2.7e-37 128.3 0.1 2.1 1 1 1 2 2 2 2 Ribosomal RNA adenine dimethylase PH PF00169.29 GAX15393.1 - 2.2e-06 28.1 1.5 0.042 14.4 0.0 4.0 3 1 1 4 4 4 2 PH domain PH_11 PF15413.6 GAX15393.1 - 0.085 13.3 0.1 0.085 13.3 0.1 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain HisKA_3 PF07730.13 GAX15393.1 - 0.15 12.6 7.7 2.3 8.8 0.4 3.0 2 0 0 2 2 2 0 Histidine kinase Rad9 PF04139.13 GAX15393.1 - 0.93 8.9 9.6 2.2 7.6 6.7 2.2 2 0 0 2 2 2 0 Rad9 FapA PF03961.13 GAX15393.1 - 3.1 6.3 24.0 0.26 9.8 10.9 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A Phage_holin_4_1 PF05105.12 GAX15394.1 - 0.046 13.9 0.7 0.07 13.3 0.7 1.3 1 1 0 1 1 1 0 Bacteriophage holin family E1-E2_ATPase PF00122.20 GAX15395.1 - 3.5e-16 59.2 0.0 1.1e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAX15395.1 - 9.2e-14 52.2 13.5 1.3e-07 32.1 2.5 4.3 4 1 0 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX15395.1 - 1.6e-07 30.9 2.3 1.7e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX15395.1 - 0.021 14.5 5.1 2.2 8.0 0.1 3.1 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase SPOUT_MTase PF02590.17 GAX15395.1 - 0.25 11.3 3.2 0.78 9.7 3.2 1.8 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase F-box-like PF12937.7 GAX15396.1 - 5.4e-07 29.4 1.5 6e-07 29.3 0.5 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAX15396.1 - 8.1e-07 28.8 0.1 1.5e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain Laminin_G_3 PF13385.6 GAX15397.1 - 0.0063 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily RXT2_N PF08595.11 GAX15397.1 - 4 7.4 11.7 0.74 9.8 0.2 3.6 3 1 1 4 4 4 0 RXT2-like, N-terminal Mito_carr PF00153.27 GAX15398.1 - 9.6e-33 112.0 8.7 1.1e-13 51.0 0.8 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Cpn60_TCP1 PF00118.24 GAX15399.1 - 1.5e-143 479.0 11.9 1.7e-143 478.8 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MitMem_reg PF13012.6 GAX15400.1 - 4e-19 69.1 1.3 4e-19 69.1 1.3 1.8 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAX15400.1 - 3.8e-18 65.6 0.2 9.1e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2009 PF09418.10 GAX15401.1 - 1.7e-157 525.2 1.4 1.1e-95 321.4 1.6 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF2009) NPV_P10 PF05531.12 GAX15401.1 - 0.066 13.7 0.2 0.65 10.5 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Aldo_ket_red PF00248.21 GAX15402.1 - 2.8e-60 204.0 0.0 3.3e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kinesin PF00225.23 GAX15403.1 - 1.5e-98 329.8 5.0 5.1e-98 328.1 5.0 2.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX15403.1 - 2.4e-20 73.0 0.0 1.3e-19 70.6 0.0 2.4 1 0 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 GAX15403.1 - 0.00066 20.0 143.9 0.072 13.3 11.3 9.1 3 1 3 8 8 8 5 Autophagy protein 16 (ATG16) IFT57 PF10498.9 GAX15403.1 - 0.0022 17.0 13.9 0.0022 17.0 13.9 6.2 4 2 2 6 6 6 2 Intra-flagellar transport protein 57 HIP1_clath_bdg PF16515.5 GAX15403.1 - 0.014 16.0 6.8 0.014 16.0 6.8 10.7 4 2 8 12 12 12 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KELK PF15796.5 GAX15403.1 - 0.015 15.8 2.5 0.015 15.8 2.5 10.5 3 2 6 10 10 10 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Basic PF01586.16 GAX15403.1 - 0.049 14.8 0.2 0.91 10.7 0.2 3.5 1 0 0 1 1 1 0 Myogenic Basic domain AlgF PF11182.8 GAX15403.1 - 0.33 10.7 5.1 0.7 9.6 3.2 2.4 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF RTBV_P46 PF06216.11 GAX15403.1 - 3.2 6.6 10.1 0.15 10.9 1.4 2.9 3 0 0 3 3 3 0 Rice tungro bacilliform virus P46 protein Nup54 PF13874.6 GAX15404.1 - 0.0011 19.1 0.8 0.0015 18.7 0.8 1.3 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.12 GAX15404.1 - 0.0015 18.6 0.4 0.002 18.2 0.4 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5089 PF17002.5 GAX15404.1 - 0.0028 17.6 2.0 0.0034 17.3 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) SNARE PF05739.19 GAX15404.1 - 0.0032 17.4 4.3 0.0082 16.1 4.3 1.7 1 1 0 1 1 1 1 SNARE domain UPF0184 PF03670.13 GAX15404.1 - 0.0059 17.0 0.7 0.0059 17.0 0.7 1.9 1 1 0 2 2 2 1 Uncharacterised protein family (UPF0184) APG17 PF04108.12 GAX15404.1 - 0.0079 15.3 1.9 0.0091 15.2 1.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Snapin_Pallidin PF14712.6 GAX15404.1 - 0.0091 16.4 2.4 0.013 15.9 2.4 1.2 1 0 0 1 1 1 1 Snapin/Pallidin DUF16 PF01519.16 GAX15404.1 - 0.011 16.2 2.5 0.014 15.9 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 CREPT PF16566.5 GAX15404.1 - 0.015 15.5 1.1 0.03 14.5 1.1 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour SKA1 PF07160.12 GAX15404.1 - 0.03 14.2 0.4 0.036 13.9 0.4 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Rabaptin PF03528.15 GAX15404.1 - 0.031 13.0 0.8 0.037 12.7 0.8 1.0 1 0 0 1 1 1 0 Rabaptin XhlA PF10779.9 GAX15404.1 - 0.033 14.4 4.1 0.76 10.0 1.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA NPV_P10 PF05531.12 GAX15404.1 - 0.046 14.2 2.1 0.086 13.3 2.1 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 GAX15404.1 - 0.051 13.6 1.1 0.066 13.2 1.1 1.1 1 0 0 1 1 1 0 Laminin Domain II PMC2NT PF08066.12 GAX15404.1 - 0.061 14.0 1.1 0.075 13.7 1.1 1.2 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF4795 PF16043.5 GAX15404.1 - 0.061 12.9 3.6 0.077 12.6 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) V-SNARE_C PF12352.8 GAX15404.1 - 0.11 12.8 2.9 0.5 10.7 0.8 2.6 1 1 2 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus LXG PF04740.12 GAX15404.1 - 0.12 12.0 2.5 12 5.5 0.1 1.9 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF948 PF06103.11 GAX15404.1 - 0.18 12.1 1.9 0.51 10.6 1.9 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 GAX15404.1 - 0.2 11.7 6.0 0.043 13.9 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 GAX15404.1 - 0.57 10.5 3.6 0.79 10.0 0.7 2.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 GAX15404.1 - 2.7 8.7 5.4 26 5.5 5.4 2.1 1 1 0 1 1 1 0 SlyX 2OG-FeII_Oxy_3 PF13640.6 GAX15405.1 - 3.7e-16 59.8 0.1 9.7e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_2 PF13532.6 GAX15405.1 - 0.00013 22.2 0.1 0.014 15.6 0.1 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX15405.1 - 0.00074 20.0 0.3 0.023 15.2 0.0 3.0 3 2 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 GAX15406.1 - 9.8e-12 45.2 14.8 0.0021 18.9 0.5 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15406.1 - 1.6e-06 28.3 2.4 0.18 12.1 0.0 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ig_4 PF16680.5 GAX15406.1 - 0.05 13.9 0.1 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Git3 PF11710.8 GAX15407.1 - 5.7e-10 39.3 5.5 1.4e-09 38.0 5.5 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 GAX15407.1 - 3.5e-06 26.4 2.0 7e-06 25.4 2.0 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Voltage_CLC PF00654.20 GAX15407.1 - 0.03 13.6 0.7 0.054 12.7 0.7 1.5 1 0 0 1 1 1 0 Voltage gated chloride channel Ist1 PF03398.14 GAX15410.1 - 2.5e-48 164.1 2.5 3.1e-48 163.8 2.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF4786 PF16027.5 GAX15410.1 - 0.11 13.0 1.4 0.21 12.1 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4786) ABC_tran PF00005.27 GAX15411.1 - 3.1e-26 92.5 0.0 5e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAX15411.1 - 1.9e-10 40.5 19.0 3.2e-10 39.8 19.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GAX15411.1 - 8.2e-08 32.4 0.0 7.4e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 GAX15411.1 - 0.00017 20.8 17.2 0.00026 20.2 17.2 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 GAX15411.1 - 0.00079 19.9 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAX15411.1 - 0.0013 18.7 0.4 0.0072 16.2 0.2 2.3 3 0 0 3 3 3 1 RsgA GTPase SMC_N PF02463.19 GAX15411.1 - 0.0013 18.2 0.1 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAX15411.1 - 0.0014 19.1 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX15411.1 - 0.0056 17.0 0.1 0.017 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAX15411.1 - 0.037 13.6 0.1 0.084 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX15411.1 - 0.042 13.6 0.2 0.093 12.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GAX15411.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 GAX15411.1 - 0.078 12.2 0.1 0.9 8.7 0.1 2.2 1 1 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 GAX15411.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAX15411.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SbcCD_C PF13558.6 GAX15411.1 - 0.37 11.1 1.1 1.8 8.9 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit His_biosynth PF00977.21 GAX15412.1 - 1.5e-41 142.4 1.1 6.4e-39 133.7 1.2 3.7 1 1 1 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 GAX15412.1 - 7.4e-23 81.3 0.0 1.3e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GAX15412.1 - 1.9e-09 37.4 0.0 4.3e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 GAX15412.1 - 5.5e-08 32.9 0.0 0.00049 20.0 0.0 2.7 3 0 0 3 3 3 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 GAX15412.1 - 0.0082 15.9 0.3 0.56 9.9 0.0 2.5 2 0 0 2 2 2 1 Peptidase C26 RRM_2 PF04059.12 GAX15413.1 - 5.6e-37 125.8 0.2 9e-37 125.2 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 GAX15413.1 - 4.6e-11 42.4 0.1 0.00044 20.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 GAX15413.1 - 0.0024 17.9 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Smg-4/UPF3 family Silic_transp PF03842.13 GAX15414.1 - 6.3e-173 575.7 22.4 7.3e-173 575.5 22.4 1.0 1 0 0 1 1 1 1 Silicon transporter Silic_transp PF03842.13 GAX15415.1 - 2.1e-172 574.0 24.4 2.5e-172 573.8 24.4 1.0 1 0 0 1 1 1 1 Silicon transporter Complex1_LYR PF05347.15 GAX15416.1 - 0.00012 22.0 0.7 0.00019 21.4 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DAP_epimerase PF01678.19 GAX15417.1 - 3.8e-68 227.2 0.0 1.7e-35 121.8 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 GAX15417.1 - 0.00055 19.5 0.0 0.00096 18.7 0.0 1.5 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein 3HCDH_N PF02737.18 GAX15418.1 - 1.1e-58 198.1 1.3 1.1e-58 198.1 1.3 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 GAX15418.1 - 1.2e-36 126.3 0.2 4.1e-36 124.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 GAX15418.1 - 2.3e-27 95.4 0.0 5.3e-18 65.4 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 GAX15418.1 - 1.6e-23 83.8 0.0 4e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Sacchrp_dh_NADP PF03435.18 GAX15418.1 - 0.00034 20.9 0.2 0.00093 19.5 0.2 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 GAX15418.1 - 0.00086 19.8 0.2 0.0031 18.1 0.2 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAX15418.1 - 0.0036 17.5 0.0 0.008 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 GAX15418.1 - 0.004 17.1 0.1 0.0091 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 GAX15418.1 - 0.02 15.2 0.2 0.054 13.8 0.2 1.8 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 GAX15418.1 - 0.021 14.5 0.1 0.054 13.2 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 GAX15418.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 GAX15418.1 - 0.049 14.3 0.6 0.29 11.8 0.6 2.3 1 1 0 1 1 1 0 PglD N-terminal domain Pyr_redox PF00070.27 GAX15418.1 - 0.05 14.2 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX15418.1 - 0.052 13.1 0.4 0.1 12.1 0.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_25 PF13649.6 GAX15418.1 - 0.06 14.1 0.0 1.9 9.3 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Shikimate_DH PF01488.20 GAX15418.1 - 0.078 13.0 0.2 0.23 11.5 0.2 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.6 GAX15418.1 - 0.091 12.5 0.2 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain Suf PF05843.14 GAX15419.1 - 2.4e-21 77.0 17.2 1.5e-08 35.0 0.8 7.5 3 2 2 6 6 6 5 Suppressor of forked protein (Suf) HAT PF02184.16 GAX15419.1 - 6.6e-20 70.8 41.3 0.00015 21.7 0.0 11.9 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 GAX15419.1 - 7.1e-18 63.8 29.8 0.0098 16.6 0.2 12.2 5 3 8 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAX15419.1 - 4.8e-15 55.8 9.0 0.023 15.2 0.0 7.3 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX15419.1 - 0.00014 21.7 25.3 1.8 8.9 0.0 9.1 13 0 0 13 13 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX15419.1 - 0.00049 20.1 8.9 24 5.5 0.1 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX15419.1 - 0.0039 17.3 8.8 1.9 8.7 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAX15419.1 - 0.008 16.2 21.5 1.8 8.6 3.1 5.8 5 2 1 6 6 6 3 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 GAX15419.1 - 0.013 16.1 20.2 10 7.0 0.2 9.8 12 1 1 13 13 12 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX15419.1 - 0.044 14.2 7.3 6 7.5 0.0 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15419.1 - 0.083 12.8 3.6 27 4.8 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX15419.1 - 0.33 11.3 17.4 0.39 11.1 1.0 6.3 7 1 1 8 8 7 0 Tetratricopeptide repeat MIT PF04212.18 GAX15419.1 - 0.46 10.6 7.4 2 8.5 1.4 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Proteasome PF00227.26 GAX15421.1 - 4.3e-18 65.5 0.7 1.4e-17 63.8 0.7 1.8 1 1 0 1 1 1 1 Proteasome subunit Alpha_kinase PF02816.18 GAX15422.1 - 4.1e-44 150.9 0.7 5.6e-44 150.5 0.7 1.2 1 0 0 1 1 1 1 Alpha-kinase family zf-NF-X1 PF01422.17 GAX15422.1 - 0.14 12.2 3.1 0.28 11.3 3.1 1.4 1 0 0 1 1 1 0 NF-X1 type zinc finger Lin0512_fam PF09585.10 GAX15423.1 - 1.5e-36 124.9 0.1 1.8e-36 124.7 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) DUF2292 PF10055.9 GAX15423.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) Lin0512_fam PF09585.10 GAX15424.1 - 1.4e-36 125.0 0.8 1.8e-36 124.7 0.8 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) adh_short PF00106.25 GAX15425.1 - 2.2e-27 95.8 0.0 2.8e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX15425.1 - 5.1e-17 62.2 0.0 6.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX15425.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX15425.1 - 0.00013 21.6 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAX15425.1 - 0.056 12.8 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RRM_1 PF00076.22 GAX15426.1 - 7.2e-51 169.9 0.9 1.6e-14 53.4 0.1 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAX15426.1 - 1.6e-06 28.0 0.3 0.006 16.6 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif SDA1 PF05285.12 GAX15426.1 - 0.0044 16.5 25.7 0.0044 16.5 25.7 3.5 3 1 1 4 4 4 1 SDA1 Limkain-b1 PF11608.8 GAX15426.1 - 0.027 14.6 0.1 2.9 8.1 0.0 2.8 2 0 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 GAX15426.1 - 0.043 13.9 0.2 2.2 8.5 0.0 3.7 4 1 0 4 4 4 0 RNA recognition motif DUF4523 PF15023.6 GAX15426.1 - 0.082 12.7 0.8 0.85 9.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) XS PF03468.14 GAX15426.1 - 0.11 12.9 4.8 3.8 7.8 0.1 4.1 4 0 0 4 4 4 0 XS domain Peptidase_S8 PF00082.22 GAX15429.1 - 1.5e-35 122.9 2.9 6.2e-35 120.9 2.9 1.7 1 1 0 1 1 1 1 Subtilase family AA_kinase PF00696.28 GAX15430.1 - 1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family SelA PF03841.13 GAX15430.1 - 0.069 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase ABC1 PF03109.16 GAX15431.1 - 9e-25 87.2 0.0 1.6e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GAX15431.1 - 0.00015 21.2 0.1 0.063 12.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GAX15431.1 - 0.00041 20.3 0.2 0.0028 17.6 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 GAX15431.1 - 0.0029 17.3 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PI3_PI4_kinase PF00454.27 GAX15431.1 - 0.078 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Pkinase_Tyr PF07714.17 GAX15431.1 - 0.093 12.0 0.1 8.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase DUF819 PF05684.12 GAX15432.1 - 1.3e-78 264.7 26.6 1.6e-78 264.4 26.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF819) Myc_N PF01056.18 GAX15433.1 - 0.014 15.3 0.2 0.014 15.3 0.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 GAX15433.1 - 1.8 7.8 6.3 1.9 7.7 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein LMF1 PF06762.14 GAX15434.1 - 0.013 14.7 1.0 0.015 14.4 1.0 1.0 1 0 0 1 1 1 0 Lipase maturation factor EF-hand_6 PF13405.6 GAX15435.1 - 4.6e-09 35.5 0.7 0.0017 18.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 GAX15435.1 - 1.9e-08 33.3 0.4 0.0092 15.5 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAX15435.1 - 5.4e-08 32.0 0.9 0.0025 17.2 0.5 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAX15435.1 - 4.3e-06 27.1 0.2 2.1e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX15435.1 - 8.8e-05 22.3 0.3 0.2 11.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair DUF2939 PF11159.8 GAX15435.1 - 0.18 12.2 1.2 1.1 9.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) CSN8_PSD8_EIF3K PF10075.9 GAX15436.1 - 0.0019 18.2 0.2 0.0056 16.7 0.2 1.8 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family MitMem_reg PF13012.6 GAX15436.1 - 0.12 12.8 0.2 0.19 12.2 0.2 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function PPR_2 PF13041.6 GAX15437.1 - 1.6e-13 50.6 1.0 1.4e-06 28.4 0.0 4.7 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.6 GAX15437.1 - 4.8e-12 45.8 0.0 5.9e-08 32.7 0.0 3.6 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX15437.1 - 1e-10 41.4 0.5 1.9e-05 24.1 0.0 2.9 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX15437.1 - 9.3e-05 22.4 10.4 0.077 13.3 0.1 4.9 4 1 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 GAX15437.1 - 0.024 14.3 0.2 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 PPR repeat Helo_like_N PF17111.5 GAX15437.1 - 0.1 11.9 0.0 2 7.7 0.0 2.6 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins zf-met2 PF12907.7 GAX15437.1 - 0.16 12.1 1.3 0.41 10.8 0.4 2.1 2 0 0 2 2 2 0 Zinc-binding Ead_Ea22 PF13935.6 GAX15437.1 - 1.9 9.2 4.5 2.4 8.8 0.0 3.1 4 0 0 4 4 4 0 Ead/Ea22-like protein NopRA1 PF16201.5 GAX15438.1 - 5.5e-30 104.5 0.2 5.2e-29 101.3 0.1 2.8 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 RNA_polI_A34 PF08208.11 GAX15438.1 - 0.072 13.2 1.4 0.12 12.4 1.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ARL6IP6 PF15062.6 GAX15439.1 - 3.5 7.8 7.0 1.2 9.3 0.2 3.4 4 0 0 4 4 4 0 Haemopoietic lineage transmembrane helix LSM PF01423.22 GAX15440.1 - 2.6e-14 52.7 0.1 3.1e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain ADH_zinc_N PF00107.26 GAX15441.1 - 5e-17 62.1 0.1 9.6e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAX15441.1 - 1.3e-16 61.9 0.0 2.9e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX15441.1 - 1.1e-07 31.7 0.1 9.3e-07 28.7 0.1 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAX15441.1 - 0.011 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase IMS PF00817.20 GAX15441.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 impB/mucB/samB family Fe_bilin_red PF05996.12 GAX15442.1 - 1e-57 195.5 2.1 1.4e-57 195.1 2.1 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Fe_bilin_red PF05996.12 GAX15443.1 - 6.6e-46 156.8 0.2 8.9e-46 156.4 0.2 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Peripla_BP_7 PF18610.1 GAX15443.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding protein domain Tim44 PF04280.15 GAX15444.1 - 1.3e-10 41.6 0.1 3.2e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 Tim44-like domain HMG_box PF00505.19 GAX15444.1 - 0.036 14.5 0.2 0.12 12.8 0.2 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box Ribosomal_S21 PF01165.20 GAX15444.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 GlutR_dimer PF00745.20 GAX15444.1 - 0.2 12.1 2.6 11 6.5 1.4 3.1 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain YtxH PF12732.7 GAX15444.1 - 0.56 10.8 2.1 3.9 8.1 0.1 2.4 2 0 0 2 2 2 0 YtxH-like protein Mpv17_PMP22 PF04117.12 GAX15445.1 - 0.00022 21.4 0.1 0.00022 21.4 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Hep_59 PF07052.11 GAX15446.1 - 2.7e-05 24.9 0.4 2.7e-05 24.9 0.4 2.5 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 HMG_box PF00505.19 GAX15447.1 - 1.4e-14 54.3 6.8 3.2e-14 53.1 6.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX15447.1 - 1.4e-09 38.4 8.5 3.6e-09 37.1 8.5 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 GAX15447.1 - 0.059 13.3 8.2 0.22 11.5 8.2 2.0 1 1 0 1 1 1 0 HMG (high mobility group) box 5 MORN PF02493.20 GAX15448.1 - 7.7e-31 104.1 39.3 4e-07 29.5 1.0 7.6 7 0 0 7 7 7 7 MORN repeat Nucleoporin_FG2 PF15967.5 GAX15448.1 - 0.38 9.2 5.4 0.55 8.7 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region XhlA PF10779.9 GAX15448.1 - 0.77 10.0 5.7 2.7 8.2 0.3 2.4 1 1 1 2 2 2 0 Haemolysin XhlA V_ATPase_I PF01496.19 GAX15448.1 - 2.1 6.2 7.4 2.9 5.7 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF720 PF05302.11 GAX15448.1 - 9.5 6.1 11.4 3.6 7.5 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF720) MORN PF02493.20 GAX15449.1 - 2e-80 260.1 152.6 2e-06 27.4 3.0 22.2 22 0 0 22 22 22 18 MORN repeat DUF3048_C PF17479.2 GAX15449.1 - 0.69 10.3 8.0 6.5 7.2 0.3 4.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain DUF4124 PF13511.6 GAX15449.1 - 1.8 9.0 11.6 0.11 12.8 0.6 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4124) MORN PF02493.20 GAX15450.1 - 7.6e-36 119.9 49.4 5.8e-07 29.0 0.1 8.5 8 0 0 8 8 8 8 MORN repeat DUF4530 PF15039.6 GAX15450.1 - 0.043 14.0 0.5 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) MORN PF02493.20 GAX15451.1 - 4.4e-07 29.4 0.5 2.2e-06 27.2 0.1 2.2 2 0 0 2 2 2 1 MORN repeat Silic_transp PF03842.13 GAX15452.1 - 6.6e-173 575.7 21.0 8.1e-173 575.4 21.0 1.0 1 0 0 1 1 1 1 Silicon transporter HMG_box PF00505.19 GAX15453.1 - 3.6e-09 36.9 3.3 0.00025 21.4 1.3 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX15453.1 - 6.2e-07 29.9 5.2 0.0027 18.3 1.5 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 GAX15453.1 - 0.19 11.7 7.0 0.083 12.9 4.0 1.9 2 0 0 2 2 2 0 HMG (high mobility group) box 5 WW PF00397.26 GAX15454.1 - 1.1e-119 390.1 62.8 3.5e-11 43.0 1.4 13.7 13 0 0 13 13 13 13 WW domain Sec16_C PF12931.7 GAX15454.1 - 1e-30 107.5 0.1 1.8e-30 106.6 0.1 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Glyco_hyd_101C PF17451.2 GAX15454.1 - 1.7e-19 70.3 36.6 0.02 15.2 0.0 13.5 10 3 2 12 12 12 7 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 GAX15454.1 - 6e-08 32.2 4.3 9.7 6.3 0.0 8.8 9 0 0 9 9 9 1 PQQ enzyme repeat PQQ_2 PF13360.6 GAX15454.1 - 8.7e-08 32.0 16.2 0.1 12.2 0.0 6.9 6 1 1 7 7 7 4 PQQ-like domain Sec16 PF12932.7 GAX15454.1 - 0.0047 17.5 0.1 0.025 15.2 0.1 2.3 1 1 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region MMADHC PF10229.9 GAX15454.1 - 0.099 12.4 3.4 0.87 9.3 0.0 3.6 4 0 0 4 4 4 0 Methylmalonic aciduria and homocystinuria type D protein Pur_ac_phosph_N PF16656.5 GAX15454.1 - 0.37 11.4 4.4 0.96 10.1 1.1 3.6 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain COPI_assoc PF08507.10 GAX15455.1 - 9.3e-10 38.7 3.3 1.2e-09 38.3 3.3 1.1 1 0 0 1 1 1 1 COPI associated protein DUF3817 PF12823.7 GAX15455.1 - 0.15 12.9 8.2 0.32 11.8 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) Lipase_3 PF01764.25 GAX15456.1 - 2.8e-11 43.5 0.0 5.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PC_rep PF01851.22 GAX15456.1 - 0.075 13.5 0.0 0.24 11.9 0.0 1.9 1 0 0 1 1 1 0 Proteasome/cyclosome repeat URO-D PF01208.17 GAX15457.1 - 1.2e-107 360.0 0.0 1.6e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SAM_2 PF07647.17 GAX15457.1 - 0.00014 21.8 0.1 0.00043 20.3 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) FKBP_C PF00254.28 GAX15457.1 - 0.0003 21.0 0.0 0.00085 19.6 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SAM_1 PF00536.30 GAX15457.1 - 0.013 16.0 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DEAD PF00270.29 GAX15458.1 - 3.7e-38 131.1 0.1 2.1e-37 128.6 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX15458.1 - 5.4e-24 84.7 0.0 1.3e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX15458.1 - 2.3e-05 24.5 0.0 0.00018 21.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3464 PF11947.8 GAX15458.1 - 0.83 9.4 3.5 7.8 6.2 0.1 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Ipi1_N PF12333.8 GAX15459.1 - 0.00093 19.7 2.4 0.0086 16.7 0.0 3.5 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation ORC5_C PF14630.6 GAX15459.1 - 0.01 15.3 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF1652 PF07865.11 GAX15459.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) PXA PF02194.15 GAX15459.1 - 0.6 10.0 6.9 5 7.1 0.2 3.4 3 1 0 3 3 3 0 PXA domain Esterase PF00756.20 GAX15461.1 - 6.3e-47 160.3 0.0 7.4e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 GAX15461.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 GAX15461.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3718 PF12514.8 GAX15461.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) V-SNARE_C PF12352.8 GAX15462.1 - 9.8e-10 38.6 3.2 1.4e-09 38.1 1.8 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus HeLo PF14479.6 GAX15462.1 - 0.021 14.6 1.0 0.3 10.9 1.0 2.0 1 1 0 1 1 1 0 Prion-inhibition and propagation kleA_kleC PF17383.2 GAX15462.1 - 0.023 15.0 0.5 0.1 13.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Rotamase PF00639.21 GAX15462.1 - 0.063 14.2 1.0 0.43 11.6 0.1 2.3 2 1 1 3 3 3 0 PPIC-type PPIASE domain DASH_Dad1 PF08649.10 GAX15462.1 - 0.094 12.9 0.4 7.1 6.9 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad1 Laminin_II PF06009.12 GAX15462.1 - 0.18 11.8 1.7 7.5 6.6 0.4 2.9 2 1 0 2 2 2 0 Laminin Domain II zf-RanBP PF00641.18 GAX15463.1 - 0.00072 18.8 6.0 0.00072 18.8 6.0 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 GAX15463.1 - 0.14 12.2 9.2 0.33 11.0 9.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon Cytochrom_CIII PF02085.16 GAX15463.1 - 1.8 9.0 6.1 3.4 8.1 6.1 1.4 1 0 0 1 1 1 0 Class III cytochrome C family zf-Sec23_Sec24 PF04810.15 GAX15463.1 - 4.1 7.5 6.0 9 6.4 0.1 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger GHMP_kinases_C PF08544.13 GAX15465.1 - 4.7e-05 23.7 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAX15465.1 - 0.00012 22.2 0.2 0.00023 21.3 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Glyco_transf_90 PF05686.12 GAX15466.1 - 1.2e-14 54.1 0.0 6.2e-14 51.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 90 AAA PF00004.29 GAX15467.1 - 8e-89 294.9 0.0 2.4e-43 147.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX15467.1 - 2.3e-24 84.9 2.4 1.1e-12 47.5 0.4 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 GAX15467.1 - 6.7e-14 51.9 0.0 1.7e-05 24.6 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX15467.1 - 2.6e-13 50.7 0.6 0.00025 21.5 0.2 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 GAX15467.1 - 2e-10 41.0 0.0 7.9e-05 22.8 0.0 3.2 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAX15467.1 - 5.1e-10 39.7 0.0 0.00016 21.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAX15467.1 - 2.1e-09 37.5 0.0 3.2e-05 24.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 GAX15467.1 - 5e-09 36.5 0.0 0.0036 17.7 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_22 PF13401.6 GAX15467.1 - 5.1e-09 36.5 0.5 0.00055 20.2 0.1 3.9 2 2 0 3 3 3 2 AAA domain AAA_5 PF07728.14 GAX15467.1 - 8.1e-09 35.6 0.1 0.00078 19.4 0.1 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAX15467.1 - 5.6e-08 32.4 0.1 0.01 15.1 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 GAX15467.1 - 5.4e-07 30.2 0.0 0.063 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAX15467.1 - 6.1e-07 29.5 0.2 0.26 11.2 0.0 3.7 3 0 0 3 3 3 2 NACHT domain Viral_helicase1 PF01443.18 GAX15467.1 - 1.2e-06 28.5 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 GAX15467.1 - 1.4e-06 28.2 0.2 0.1 12.4 0.0 2.8 2 1 0 3 3 3 2 IstB-like ATP binding protein TsaE PF02367.17 GAX15467.1 - 3.2e-06 27.2 0.0 0.076 13.0 0.0 3.1 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 GAX15467.1 - 3.2e-06 27.6 0.1 0.095 13.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 GAX15467.1 - 3.5e-06 26.5 3.0 0.05 13.0 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAX15467.1 - 5.6e-06 26.7 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 GAX15467.1 - 1.2e-05 25.4 0.0 0.13 12.1 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 GAX15467.1 - 1.7e-05 24.4 0.0 0.093 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region CDC48_N PF02359.18 GAX15467.1 - 1.9e-05 24.8 0.7 5.3e-05 23.3 0.7 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain ATPase PF06745.13 GAX15467.1 - 2e-05 24.1 0.0 0.097 12.0 0.0 2.8 2 1 0 2 2 2 2 KaiC Zeta_toxin PF06414.12 GAX15467.1 - 2.2e-05 23.9 0.0 0.012 14.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 GAX15467.1 - 3.3e-05 24.4 0.0 0.44 11.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter Vps4_C PF09336.10 GAX15467.1 - 6.4e-05 22.9 0.2 0.00063 19.7 0.0 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain ATPase_2 PF01637.18 GAX15467.1 - 7.8e-05 22.7 0.0 1.4 8.7 0.0 3.4 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 GAX15467.1 - 0.00018 20.7 0.2 0.064 12.3 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 GAX15467.1 - 0.00036 20.3 0.1 0.93 9.2 0.0 3.0 3 1 0 3 3 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 GAX15467.1 - 0.00037 19.8 0.0 0.98 8.5 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activ_2 PF14532.6 GAX15467.1 - 0.00053 20.1 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 GAX15467.1 - 0.00058 19.5 1.4 2.5 7.6 0.1 3.8 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 GAX15467.1 - 0.00098 18.9 0.0 1.3 8.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 GAX15467.1 - 0.0014 18.1 0.1 2 7.8 0.0 3.0 3 0 0 3 3 2 1 PhoH-like protein Bac_DnaA PF00308.18 GAX15467.1 - 0.0019 18.1 0.0 0.94 9.3 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_3 PF07726.11 GAX15467.1 - 0.0022 17.8 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 GAX15467.1 - 0.0028 17.5 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 GAX15467.1 - 0.004 17.3 0.1 8.6 6.5 0.0 3.4 4 0 0 4 4 3 0 Cytidylate kinase-like family DUF2075 PF09848.9 GAX15467.1 - 0.0068 15.7 0.0 0.79 8.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GAX15467.1 - 0.0074 15.4 0.0 1.3 8.0 0.0 2.9 2 1 0 2 2 2 1 Type II/IV secretion system protein Hydin_ADK PF17213.3 GAX15467.1 - 0.0097 16.2 1.7 9.7 6.4 0.0 3.3 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF815 PF05673.13 GAX15467.1 - 0.015 14.4 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Molydop_binding PF01568.21 GAX15467.1 - 0.023 14.7 0.1 0.078 13.0 0.1 1.8 1 1 1 2 2 1 0 Molydopterin dinucleotide binding domain AAA_19 PF13245.6 GAX15467.1 - 0.044 14.1 0.4 13 6.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 GAX15467.1 - 0.048 13.4 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 GAX15467.1 - 0.062 13.3 0.1 14 5.7 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 GAX15467.1 - 0.065 13.1 0.0 24 4.8 0.0 3.2 2 0 0 2 2 2 0 NTPase SH3_2 PF07653.17 GAX15467.1 - 0.088 12.5 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain Arteri_nsp7a PF16749.5 GAX15467.1 - 0.099 12.8 0.0 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha ADK PF00406.22 GAX15467.1 - 0.11 12.6 0.1 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase PduV-EutP PF10662.9 GAX15467.1 - 0.11 12.3 0.0 19 5.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAX15467.1 - 0.11 11.9 0.0 4.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IPT PF01745.16 GAX15467.1 - 0.15 11.4 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase GTP1_OBG PF01018.22 GAX15468.1 - 2.1e-33 115.1 8.4 3e-33 114.6 8.4 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 GAX15468.1 - 3e-23 82.1 0.0 4.8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX15468.1 - 1.1e-10 41.3 0.0 3.4e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAX15468.1 - 0.00011 21.8 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAX15468.1 - 0.00025 20.1 2.4 0.023 13.7 0.1 2.6 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 GAX15468.1 - 0.00039 20.3 0.0 0.0087 15.9 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 GAX15468.1 - 0.002 18.2 0.0 2.7 8.0 0.0 2.4 1 1 0 2 2 2 2 Dynamin family Arf PF00025.21 GAX15468.1 - 0.0055 16.2 0.0 0.62 9.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 GAX15468.1 - 0.059 13.9 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 GAX15468.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF4050 PF13259.6 GAX15470.1 - 0.00093 19.6 0.0 0.00099 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) RPT PF13446.6 GAX15470.1 - 0.024 14.6 0.1 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 A repeated domain in UCH-protein DNA_primase_S PF01896.19 GAX15471.1 - 8.6e-46 156.2 0.0 2e-45 155.0 0.0 1.6 1 1 0 1 1 1 1 DNA primase small subunit P53 PF00870.18 GAX15471.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 P53 DNA-binding domain Chisel PF15355.6 GAX15472.1 - 0.0068 16.6 0.2 0.029 14.6 0.0 2.1 1 1 2 3 3 3 1 Stretch-responsive small skeletal muscle X protein, Chisel PBP1_TM PF14812.6 GAX15472.1 - 0.069 13.5 17.0 0.94 9.9 0.4 3.1 1 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PA PF02225.22 GAX15473.1 - 2.3e-08 34.0 0.1 5.6e-08 32.7 0.1 1.5 1 1 0 1 1 1 1 PA domain DZR PF12773.7 GAX15473.1 - 0.0046 17.0 2.7 0.0087 16.1 2.7 1.4 1 0 0 1 1 1 1 Double zinc ribbon ZNRF_3_ecto PF18212.1 GAX15473.1 - 0.031 14.3 0.8 0.093 12.7 0.1 2.2 2 1 0 2 2 2 0 ZNRF-3 Ectodomain IMPa_N_2 PF18650.1 GAX15473.1 - 0.064 12.5 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain FG-GAP_2 PF14312.6 GAX15474.1 - 6.5e-85 279.2 36.5 5.6e-16 58.5 5.2 7.2 7 0 0 7 7 7 7 FG-GAP repeat HisK_sensor PF18698.1 GAX15474.1 - 0.0021 18.5 4.2 0.41 11.0 0.0 4.1 4 0 0 4 4 4 1 Histidine kinase sensor domain Kelch_3 PF13415.6 GAX15474.1 - 0.053 13.8 6.5 3.7 7.9 0.2 4.7 6 0 0 6 6 6 0 Galactose oxidase, central domain AnfO_nitrog PF09582.10 GAX15474.1 - 0.056 12.8 0.0 33 3.7 0.0 3.2 3 0 0 3 3 3 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Kelch_6 PF13964.6 GAX15474.1 - 0.1 12.9 5.2 9.6 6.7 0.0 4.9 6 0 0 6 6 6 0 Kelch motif V-ATPase_C PF03223.15 GAX15475.1 - 1.5e-87 294.4 0.0 1.9e-87 294.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C MukB_hinge PF16330.5 GAX15475.1 - 0.092 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 MukB hinge domain Kri1 PF05178.12 GAX15475.1 - 0.12 13.0 1.7 0.18 12.4 0.0 2.1 3 0 0 3 3 3 0 KRI1-like family LON_substr_bdg PF02190.16 GAX15476.1 - 2.6e-10 40.5 0.0 6.6e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain FAM178 PF14816.6 GAX15476.1 - 0.019 14.0 0.2 0.14 11.1 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function, FAM178 DUF410 PF04190.13 GAX15478.1 - 2.8e-39 135.4 0.0 3.6e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) MBOAT_2 PF13813.6 GAX15479.1 - 2.9e-12 46.7 0.0 8.5e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT PF03062.19 GAX15479.1 - 1.6e-07 31.0 4.8 1.6e-07 31.0 4.8 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Cyclin_N PF00134.23 GAX15480.1 - 5.4e-17 61.7 0.5 9e-17 61.0 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX15480.1 - 2.8e-05 24.2 1.0 0.00017 21.7 0.1 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Kinesin PF00225.23 GAX15481.1 - 2.1e-101 339.2 3.9 3.3e-101 338.5 0.0 2.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX15481.1 - 3e-27 95.4 0.0 1.2e-26 93.4 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Rotamase PF00639.21 GAX15481.1 - 0.16 12.9 0.2 0.16 12.9 0.2 5.2 4 0 0 4 4 4 0 PPIC-type PPIASE domain FTO_CTD PF12934.7 GAX15481.1 - 2.8 7.7 13.4 0.55 10.0 1.1 4.3 3 0 0 3 3 3 0 FTO C-terminal domain Taq-exonuc PF09281.10 GAX15481.1 - 4.7 7.2 8.3 0.25 11.4 0.5 2.7 3 0 0 3 3 3 0 Taq polymerase, exonuclease Kinesin_assoc PF16183.5 GAX15481.1 - 7.2 6.7 33.4 0.12 12.5 2.2 5.5 3 2 1 5 5 5 0 Kinesin-associated RRM_1 PF00076.22 GAX15482.1 - 1.7e-11 43.7 0.0 6.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med26 PF08711.11 GAX15482.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RRM_5 PF13893.6 GAX15482.1 - 0.00078 19.0 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ku_C PF03730.14 GAX15482.1 - 5.8 7.7 6.8 0.38 11.5 0.9 2.1 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Pantoate_ligase PF02569.15 GAX15483.1 - 6.3e-95 317.4 0.1 7.1e-95 317.2 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PALP PF00291.25 GAX15484.1 - 8.6e-81 271.6 3.8 1.2e-80 271.1 3.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 GAX15484.1 - 3.7e-43 145.2 0.0 7.9e-25 86.5 0.0 2.9 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase EPOP PF15223.6 GAX15484.1 - 0.26 10.6 0.1 0.39 10.0 0.1 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein potato_inhibit PF00280.18 GAX15485.1 - 3.8e-17 62.7 0.0 7.6e-17 61.7 0.0 1.5 2 0 0 2 2 2 1 Potato inhibitor I family Inhibitor_I78 PF11720.8 GAX15485.1 - 0.0029 17.6 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family SKIP_SNW PF02731.15 GAX15486.1 - 7.8e-64 214.2 2.4 7.8e-64 214.2 2.4 3.0 3 0 0 3 3 3 1 SKIP/SNW domain SUIM_assoc PF16619.5 GAX15486.1 - 0.00014 21.8 2.8 0.00014 21.8 2.8 3.7 4 0 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 Cwf_Cwc_15 PF04889.12 GAX15486.1 - 0.41 10.3 24.4 0.13 11.9 18.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Paf1 PF03985.13 GAX15488.1 - 1.9 7.4 14.8 2.5 7.0 14.8 1.2 1 0 0 1 1 1 0 Paf1 Nucleo_P87 PF07267.11 GAX15488.1 - 6.8 5.4 9.4 8.7 5.1 9.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HMGL-like PF00682.19 GAX15489.1 - 2.3e-86 289.6 0.0 3.2e-86 289.2 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 GAX15489.1 - 4e-34 117.4 0.1 7.3e-34 116.5 0.1 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4225 PF13988.6 GAX15489.1 - 0.073 12.6 0.0 0.35 10.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4225) Ribosomal_L24e PF01246.20 GAX15490.1 - 1.1e-19 70.4 0.8 1.6e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e BTHB PF18410.1 GAX15491.1 - 0.0076 16.0 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Basic tilted helix bundle domain GRIP PF01465.20 GAX15491.1 - 0.11 12.4 0.1 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 GRIP domain CN_hydrolase PF00795.22 GAX15492.1 - 1e-64 218.4 0.0 1.2e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sulfotransfer_3 PF13469.6 GAX15493.1 - 1.2e-05 25.9 0.8 2.8e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 GAX15493.1 - 0.02 14.4 0.1 0.034 13.6 0.1 1.5 1 0 0 1 1 1 0 Sulfotransferase domain CCDC144C PF14915.6 GAX15494.1 - 0.035 13.2 0.1 0.042 13.0 0.1 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Lactamase_B PF00753.27 GAX15495.1 - 2.6e-11 43.9 0.1 1e-10 42.0 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAX15495.1 - 5.6e-06 26.0 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain cNMP_binding PF00027.29 GAX15495.1 - 0.0028 17.7 0.0 0.046 13.8 0.0 3.0 4 0 0 4 4 4 1 Cyclic nucleotide-binding domain Methyltransf_23 PF13489.6 GAX15496.1 - 7.2e-22 78.0 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX15496.1 - 3.5e-17 62.8 0.0 7.5e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX15496.1 - 4.4e-14 53.0 0.0 1.7e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX15496.1 - 1.1e-12 47.9 0.0 1.6e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX15496.1 - 2.3e-11 44.3 0.0 5e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX15496.1 - 2.6e-11 43.6 0.0 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAX15496.1 - 0.0021 17.7 0.0 0.0045 16.6 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 GAX15496.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.8 GAX15496.1 - 0.043 13.0 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Arm-DNA-bind_2 PF12167.8 GAX15498.1 - 0.018 14.9 6.1 0.15 12.0 0.3 3.9 2 1 2 4 4 4 0 Arm DNA-binding domain PRTase_3 PF15610.6 GAX15498.1 - 0.085 12.1 6.9 1.4 8.1 1.4 3.2 1 1 2 3 3 3 0 PRTase ComF-like NAPRTase_N PF17767.1 GAX15498.1 - 0.29 11.5 3.0 0.3 11.5 0.3 2.3 2 1 1 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain MEF2_binding PF09047.10 GAX15498.1 - 2.7 7.9 7.1 17 5.4 0.2 4.0 5 0 0 5 5 5 0 MEF2 binding Sacchrp_dh_NADP PF03435.18 GAX15498.1 - 5.2 7.3 11.9 2.2 8.5 0.5 3.9 1 1 4 5 5 5 0 Saccharopine dehydrogenase NADP binding domain RNase_T PF00929.24 GAX15499.1 - 4.9e-09 36.9 0.0 7.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease TcdB_N PF12918.7 GAX15500.1 - 0.066 13.5 0.6 19 5.6 0.0 3.0 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Hydrolase_4 PF12146.8 GAX15502.1 - 5.1e-13 48.9 0.0 1.1e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX15502.1 - 7.2e-12 45.5 0.1 2.2e-11 43.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX15502.1 - 2.7e-10 41.2 0.0 9.3e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 GAX15502.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 GAX15502.1 - 0.016 14.8 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 GAX15502.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Palm_thioest PF02089.15 GAX15502.1 - 0.037 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Thioesterase PF00975.20 GAX15502.1 - 0.07 13.2 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain HEM4 PF02602.15 GAX15503.1 - 4.9e-42 143.9 0.0 6.1e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD CUB_2 PF02408.20 GAX15503.1 - 0.02 14.7 0.7 0.057 13.2 0.2 1.8 1 1 0 2 2 2 0 CUB-like domain adh_short PF00106.25 GAX15504.1 - 2e-23 82.9 2.1 7.3e-19 68.0 2.1 3.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX15504.1 - 4.9e-12 45.9 0.6 1.6e-08 34.4 0.6 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX15504.1 - 8.3e-09 35.6 0.3 1.4e-08 34.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX15504.1 - 4.7e-06 26.2 0.1 8.1e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 GAX15504.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 GAX15504.1 - 0.012 14.9 0.2 0.017 14.4 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2020 PF09449.10 GAX15504.1 - 0.058 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) NAD_binding_3 PF03447.16 GAX15504.1 - 0.076 13.7 2.2 0.41 11.3 1.5 2.2 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAX15504.1 - 0.09 12.9 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 GAX15504.1 - 0.11 12.4 0.5 0.29 11.0 0.2 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TraL PF07178.11 GAX15505.1 - 0.11 12.9 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 TraL protein Glyco_trans_1_2 PF13524.6 GAX15506.1 - 6.7e-13 48.9 0.1 1.4e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_92 PF01697.27 GAX15507.1 - 5.6e-08 32.8 5.2 1.3e-07 31.6 4.1 2.1 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GAX15507.1 - 8.5e-08 32.6 0.8 8.5e-08 32.6 0.8 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Kinesin_assoc PF16183.5 GAX15508.1 - 0.052 13.7 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinesin-associated HEPN_RES_NTD1 PF18870.1 GAX15508.1 - 0.15 12.2 4.8 4.5 7.5 0.7 2.7 2 1 1 3 3 3 0 HEPN/RES N-terminal domain 1 PGM_PMM_I PF02878.16 GAX15511.1 - 6.9e-18 64.7 0.4 1.3e-07 31.5 0.1 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 GAX15511.1 - 1.8e-10 40.8 0.1 4.3e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 GAX15511.1 - 0.042 14.5 1.6 0.58 10.8 0.4 3.1 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MIF PF01187.18 GAX15512.1 - 2.2e-21 76.3 0.1 3.8e-21 75.5 0.0 1.4 2 0 0 2 2 2 1 Macrophage migration inhibitory factor (MIF) Bestrophin PF01062.21 GAX15513.1 - 9.6e-27 94.1 2.6 1.4e-26 93.6 2.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Acyltransf_C PF16076.5 GAX15515.1 - 3.4e-11 43.1 0.0 6.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF4191 PF13829.6 GAX15515.1 - 1 8.7 8.0 0.21 10.9 1.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Ribul_P_3_epim PF00834.19 GAX15516.1 - 4.3e-67 225.4 0.0 4.9e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 GAX15516.1 - 0.003 17.8 0.1 0.0061 16.8 0.1 1.5 1 0 0 1 1 1 1 Predicted Peptidoglycan domain ThiG PF05690.14 GAX15516.1 - 0.0089 15.4 0.2 0.016 14.5 0.2 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Radical_SAM PF04055.21 GAX15516.1 - 0.042 14.2 0.0 0.67 10.3 0.0 2.6 1 1 2 3 3 3 0 Radical SAM superfamily His_biosynth PF00977.21 GAX15516.1 - 0.14 11.6 0.1 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Rieske PF00355.26 GAX15518.1 - 4.1e-16 58.7 0.0 6.9e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GAX15518.1 - 6.4e-07 29.4 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase RNHCP PF12647.7 GAX15518.1 - 0.08 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 RNHCP domain PDH PF02153.17 GAX15519.1 - 5.4e-12 45.3 0.0 3.4e-06 26.3 0.0 3.0 2 1 0 2 2 2 2 Prephenate dehydrogenase F420_oxidored PF03807.17 GAX15519.1 - 9.5e-05 22.9 0.2 0.00047 20.7 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAX15519.1 - 0.0059 16.0 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 GAX15519.1 - 0.035 14.1 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K-box PF01486.17 GAX15519.1 - 0.064 13.4 0.2 0.064 13.4 0.2 2.2 2 0 0 2 2 2 0 K-box region TrkA_N PF02254.18 GAX15519.1 - 0.084 13.1 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain DUF1104 PF06518.11 GAX15519.1 - 1.2 9.6 6.0 1.7 9.1 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) ZapB PF06005.12 GAX15519.1 - 1.6 9.3 6.8 3 8.3 1.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Hydrolase_3 PF08282.12 GAX15520.1 - 6.6e-40 137.5 0.0 9.7e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GAX15520.1 - 7e-09 35.6 0.0 9.8e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GAX15520.1 - 9.6e-06 26.0 0.1 0.00091 19.6 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX15520.1 - 0.065 13.6 0.1 12 6.3 0.0 2.6 2 2 0 2 2 2 0 haloacid dehalogenase-like hydrolase FHA PF00498.26 GAX15521.1 - 2e-12 47.2 0.0 9.6e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAX15521.1 - 2.6e-05 24.4 0.0 0.00014 22.2 0.0 2.3 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF4407 PF14362.6 GAX15521.1 - 0.2 11.0 14.4 0.34 10.2 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 GAX15521.1 - 1.2 9.6 18.4 2.8 8.4 5.8 2.2 2 0 0 2 2 2 0 AAA domain Sec34 PF04136.15 GAX15521.1 - 2.1 8.2 12.0 3.3 7.6 3.8 2.6 2 1 0 2 2 2 0 Sec34-like family TFR_dimer PF04253.15 GAX15521.1 - 2.1 8.4 7.1 0.36 10.9 1.8 2.3 1 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain Atg14 PF10186.9 GAX15521.1 - 2.2 7.3 17.8 0.78 8.8 8.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 GAX15521.1 - 2.7 8.5 14.6 4.7 7.8 3.0 3.8 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 GAX15521.1 - 7.2 5.4 9.9 9.7 5.0 9.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2203 PF09969.9 GAX15521.1 - 7.8 7.2 10.8 13 6.5 2.7 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cpn60_TCP1 PF00118.24 GAX15522.1 - 1.9e-84 284.1 14.4 2.8e-84 283.5 14.4 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DEAD_2 PF06733.15 GAX15523.1 - 6.2e-46 156.2 0.1 2.6e-42 144.4 0.0 2.6 3 0 0 3 3 3 2 DEAD_2 Helicase_C_2 PF13307.6 GAX15523.1 - 1.1e-44 152.7 0.1 3.9e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 GAX15523.1 - 1.2e-25 90.3 0.1 1.2e-21 77.3 0.0 2.7 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 GAX15523.1 - 3.9e-08 33.5 0.0 0.00054 20.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX15523.1 - 6.3e-05 22.8 0.0 0.033 14.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF2075 PF09848.9 GAX15523.1 - 0.0079 15.5 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 GAX15523.1 - 0.055 13.3 0.3 0.12 12.2 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX15523.1 - 0.091 13.0 0.0 12 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX15523.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region vATP-synt_E PF01991.18 GAX15523.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit RVT_2 PF07727.14 GAX15524.1 - 2e-21 76.8 0.3 5.8e-21 75.2 0.3 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX15524.1 - 0.014 15.4 4.2 0.035 14.2 4.2 1.7 1 0 0 1 1 1 0 Zinc knuckle IMPDH PF00478.25 GAX15524.1 - 0.13 11.3 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Mo-nitro_C PF06967.11 GAX15524.1 - 0.16 11.9 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus AAA_16 PF13191.6 GAX15525.1 - 2e-08 34.8 0.2 5.9e-08 33.3 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain ORC4_C PF14629.6 GAX15525.1 - 4.6e-05 22.9 0.1 8.8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus TniB PF05621.11 GAX15525.1 - 0.0083 15.5 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 GAX15525.1 - 0.012 15.9 1.2 0.05 13.9 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 GAX15525.1 - 0.018 15.0 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX15525.1 - 0.058 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DAP3 PF10236.9 GAX15525.1 - 0.093 11.9 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Pet191_N PF10203.9 GAX15525.1 - 0.15 12.4 0.8 0.34 11.2 0.2 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Gpi16 PF04113.14 GAX15528.1 - 2.2e-16 59.4 0.0 3.2e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF1995 PF09353.10 GAX15529.1 - 3.5e-25 89.2 0.2 1.2e-24 87.5 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) MRP-S33 PF08293.11 GAX15529.1 - 0.13 12.5 0.0 0.48 10.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 SBP_bac_5 PF00496.22 GAX15530.1 - 5.2e-52 177.1 0.4 6.1e-52 176.8 0.4 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle TPR_12 PF13424.6 GAX15531.1 - 5.7e-09 36.2 4.2 0.004 17.4 0.8 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15531.1 - 7.2e-09 35.1 8.3 0.035 13.9 0.2 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat Methyltransf_25 PF13649.6 GAX15531.1 - 1.7e-08 35.0 0.0 5.3e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX15531.1 - 1.1e-07 32.4 0.0 3.3e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TPR_2 PF07719.17 GAX15531.1 - 5.3e-07 29.3 10.8 1.9 8.8 0.3 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX15531.1 - 7.7e-07 28.7 2.1 0.04 13.9 0.3 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX15531.1 - 7.8e-07 28.8 11.6 0.022 15.0 0.4 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat Methyltransf_23 PF13489.6 GAX15531.1 - 1.4e-06 28.3 0.0 3.5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX15531.1 - 8.3e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX15531.1 - 2.6e-05 24.9 0.0 6.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MIT PF04212.18 GAX15531.1 - 0.00084 19.4 4.4 0.63 10.2 0.0 3.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 GAX15531.1 - 0.00093 19.0 3.7 0.037 13.9 0.8 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX15531.1 - 0.00094 19.4 1.1 9.9 6.8 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX15531.1 - 0.00097 19.7 8.4 0.021 15.4 1.4 4.0 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX15531.1 - 0.0084 15.8 9.5 3.4 7.4 0.4 4.2 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 GAX15531.1 - 0.11 13.3 1.8 64 4.8 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF627 PF04781.12 GAX15531.1 - 0.19 11.7 3.7 2.6 8.1 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_6 PF13174.6 GAX15531.1 - 0.73 10.6 6.1 1e+02 3.9 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Spc24 PF08286.11 GAX15533.1 - 7.8e-06 26.1 5.3 0.00029 21.0 5.3 2.1 1 1 0 1 1 1 1 Spc24 subunit of Ndc80 GatB_Yqey PF02637.18 GAX15533.1 - 0.0019 18.1 2.5 0.0027 17.6 2.5 1.1 1 0 0 1 1 1 1 GatB domain DUF3837 PF12939.7 GAX15533.1 - 0.0042 17.5 1.3 0.0089 16.4 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3837) DUF2202 PF09968.9 GAX15533.1 - 0.0056 16.5 0.7 0.0081 16.0 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein domain (DUF2202) DHR10 PF18595.1 GAX15533.1 - 0.0057 16.7 15.2 0.0089 16.1 15.2 1.3 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain DUF2408 PF10303.9 GAX15533.1 - 0.03 14.9 8.2 0.043 14.4 8.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF572 PF04502.13 GAX15533.1 - 0.058 13.0 4.8 0.068 12.8 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ZapD PF07072.11 GAX15533.1 - 0.099 12.4 4.5 0.14 11.9 4.5 1.3 1 0 0 1 1 1 0 Cell division protein Exonuc_VII_L PF02601.15 GAX15533.1 - 0.1 12.1 4.3 0.13 11.8 4.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 GAX15533.1 - 0.14 11.4 8.0 0.18 11.1 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 GAX15533.1 - 0.15 12.5 7.2 0.24 11.8 7.2 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) BBP1_N PF15271.6 GAX15533.1 - 0.18 12.6 2.2 0.27 12.0 2.2 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein Sec8_exocyst PF04048.14 GAX15533.1 - 0.18 11.7 6.2 1.4 8.8 2.5 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF2935 PF11155.8 GAX15533.1 - 0.18 12.1 4.7 0.67 10.3 4.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Prp18 PF02840.15 GAX15533.1 - 0.23 11.5 4.5 0.32 11.0 4.1 1.4 1 1 0 1 1 1 0 Prp18 domain Tmemb_cc2 PF10267.9 GAX15533.1 - 0.24 10.5 9.6 0.33 10.0 9.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TMPIT PF07851.13 GAX15533.1 - 0.25 10.6 7.6 0.33 10.1 7.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein V-SNARE PF05008.15 GAX15533.1 - 0.26 11.7 8.2 0.45 10.9 8.2 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus PRKG1_interact PF15898.5 GAX15533.1 - 0.26 12.2 11.7 32 5.5 11.8 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain KNOX2 PF03791.13 GAX15533.1 - 0.29 10.7 6.2 0.87 9.1 0.7 2.6 1 1 1 2 2 2 0 KNOX2 domain Sec20 PF03908.13 GAX15533.1 - 0.37 10.7 3.4 0.66 9.9 1.2 2.1 1 1 1 2 2 2 0 Sec20 UPF0242 PF06785.11 GAX15533.1 - 0.45 10.6 10.3 0.61 10.2 10.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 GAX15533.1 - 0.49 10.8 8.2 0.36 11.2 6.3 1.7 1 1 1 2 2 2 0 Syntaxin-like protein DUF948 PF06103.11 GAX15533.1 - 0.78 10.0 3.0 2.1 8.6 1.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.6 GAX15533.1 - 0.92 9.9 14.6 0.32 11.4 8.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FapA PF03961.13 GAX15533.1 - 0.95 8.0 5.1 1.2 7.6 5.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Laminin_II PF06009.12 GAX15533.1 - 0.99 9.4 6.2 1.5 8.9 6.2 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF1043 PF06295.12 GAX15533.1 - 1.6 8.7 8.2 2.2 8.3 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Med9 PF07544.13 GAX15533.1 - 2.3 8.3 10.1 2.3 8.4 3.0 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LMBR1 PF04791.16 GAX15533.1 - 2.6 6.9 4.0 3.2 6.6 4.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4337 PF14235.6 GAX15533.1 - 3.3 7.8 7.3 5.2 7.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) YlqD PF11068.8 GAX15533.1 - 5.9 7.3 14.6 15 5.9 14.6 1.6 1 1 0 1 1 1 0 YlqD protein efThoc1 PF11957.8 GAX15534.1 - 6e-32 111.0 4.5 2.1e-28 99.3 4.5 2.5 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor zf-Nse PF11789.8 GAX15536.1 - 1.2e-15 57.0 0.0 2.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 GAX15536.1 - 0.00017 21.7 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 U-box domain zf-C3HC4_2 PF13923.6 GAX15536.1 - 0.0011 18.8 0.1 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX15536.1 - 0.0023 17.9 0.0 0.0064 16.5 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 GAX15536.1 - 0.0066 16.2 0.3 0.016 15.0 0.3 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 GAX15536.1 - 0.066 13.6 0.2 0.16 12.3 0.2 1.8 1 0 0 1 1 1 0 Ring finger domain tRNA-synt_2 PF00152.20 GAX15537.1 - 7.8e-77 258.4 0.0 1e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX15537.1 - 3.3e-13 49.4 0.0 1.3e-12 47.6 0.1 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain WHEP-TRS PF00458.20 GAX15537.1 - 2.9e-08 33.7 0.8 5.7e-08 32.8 0.8 1.5 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2d PF01409.20 GAX15537.1 - 7.1e-05 22.4 0.1 0.27 10.7 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Use1 PF09753.9 GAX15537.1 - 0.0099 15.6 1.8 0.016 14.9 1.8 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 DnaJ PF00226.31 GAX15538.1 - 1.9e-18 66.4 0.4 3.1e-18 65.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Chloroa_b-bind PF00504.21 GAX15539.1 - 1.4e-34 120.0 0.0 1.9e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NMT1 PF09084.11 GAX15540.1 - 2.2e-48 165.1 0.0 2.9e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Glyco_trans_1_2 PF13524.6 GAX15541.1 - 2.1e-09 37.6 0.0 9.7e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 FAT PF02259.23 GAX15541.1 - 0.16 11.2 0.0 12 4.9 0.0 2.1 1 1 1 2 2 2 0 FAT domain Asp_Arg_Hydrox PF05118.15 GAX15542.1 - 5.5e-37 127.0 0.0 1.1e-36 126.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.17 GAX15542.1 - 0.031 14.4 1.5 1.2 9.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX15542.1 - 0.076 13.5 0.5 0.23 12.0 0.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15542.1 - 0.13 12.1 1.4 8.1 6.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX15542.1 - 0.22 11.7 2.0 0.27 11.3 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Arm PF00514.23 GAX15543.1 - 1.1e-14 53.9 9.0 0.00063 19.7 0.1 8.9 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 GAX15543.1 - 7.8e-11 41.9 1.0 0.11 12.5 0.0 5.5 2 1 3 6 6 6 5 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.14 GAX15543.1 - 0.00034 20.0 1.3 0.031 13.6 0.2 2.9 1 1 0 2 2 2 2 V-ATPase subunit H RICTOR_N PF14664.6 GAX15543.1 - 0.021 13.8 0.3 0.35 9.8 0.2 2.2 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term DUF2095 PF09868.9 GAX15543.1 - 0.071 13.1 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) PrmA PF06325.13 GAX15544.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX15544.1 - 2e-06 28.4 0.1 1.5e-05 25.6 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX15544.1 - 2.5e-05 24.1 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 GAX15544.1 - 0.0002 22.0 0.0 0.00051 20.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX15544.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX15544.1 - 0.037 13.8 0.0 0.064 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 GAX15544.1 - 0.086 12.2 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Peptidase_M1 PF01433.20 GAX15545.1 - 2.8e-48 164.4 0.1 5.9e-48 163.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GAX15545.1 - 1.2e-36 125.3 0.1 2.7e-36 124.1 0.1 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GAX15545.1 - 1.7e-24 87.0 0.0 2.6e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 GAX15545.1 - 0.33 11.4 2.1 6.2 7.2 2.1 2.6 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_S41 PF03572.18 GAX15546.1 - 1.9e-42 144.7 0.0 3.3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GAX15546.1 - 1.6e-11 43.8 0.1 4.4e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX15546.1 - 2.6e-08 34.1 0.1 4.4e-07 30.1 0.1 2.8 2 1 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX15546.1 - 7.6e-08 32.6 0.2 1.4e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_C1 PF14684.6 GAX15546.1 - 2.1e-06 27.7 0.1 4.3e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Tricorn protease C1 domain Plasmod_dom_1 PF09715.10 GAX15547.1 - 0.13 12.3 0.3 0.24 11.5 0.3 1.4 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF4199 PF13858.6 GAX15547.1 - 0.21 12.0 3.1 1 9.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Med26 PF08711.11 GAX15549.1 - 0.025 14.6 0.0 0.12 12.4 0.0 2.2 1 0 0 1 1 1 0 TFIIS helical bundle-like domain WD40 PF00400.32 GAX15550.1 - 2e-21 75.9 10.6 3.2e-06 27.8 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15550.1 - 0.00013 22.2 0.2 0.041 14.2 0.1 3.9 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1681 PF07933.14 GAX15551.1 - 5.8e-48 162.4 0.0 7e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) LIDHydrolase PF10230.9 GAX15552.1 - 6.3e-34 117.7 0.0 1.1e-33 116.9 0.0 1.4 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 GAX15552.1 - 1.5e-05 24.4 0.0 2.2e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX15552.1 - 0.0012 18.6 0.0 0.0071 16.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF5519 PF17648.1 GAX15553.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5519) Lipase_GDSL_2 PF13472.6 GAX15554.1 - 0.0055 17.1 0.0 0.0097 16.3 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX15554.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Branch PF02485.21 GAX15555.1 - 4.3e-14 52.6 0.4 9.6e-14 51.5 0.2 1.6 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Ribosom_S12_S23 PF00164.25 GAX15556.1 - 9.7e-50 167.0 0.8 1.2e-49 166.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF3727 PF12527.8 GAX15557.1 - 1.9e-19 69.7 8.2 1.9e-19 69.7 8.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3727) PB1 PF00564.24 GAX15557.1 - 0.021 14.7 0.2 0.059 13.3 0.2 1.7 1 0 0 1 1 1 0 PB1 domain E7 PF00527.18 GAX15557.1 - 0.17 12.1 5.6 3.1 8.1 5.6 2.2 1 1 0 1 1 1 0 E7 protein, Early protein CENP-B_dimeris PF09026.10 GAX15557.1 - 3.3 8.2 10.3 3.5 8.1 8.8 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF5305 PF17231.2 GAX15559.1 - 0.055 12.9 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) CbtA PF09490.10 GAX15559.1 - 0.061 13.1 0.2 0.08 12.7 0.2 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SfLAP PF11139.8 GAX15559.1 - 0.063 12.7 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein TetR_C_19 PF17924.1 GAX15559.1 - 0.093 13.3 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GTP_EFTU PF00009.27 GAX15560.1 - 1.3e-30 106.4 0.0 2.7e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAX15560.1 - 3.5e-15 56.0 0.1 1.6e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 GAX15560.1 - 1.5e-06 28.2 0.4 6e-06 26.3 0.4 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAX15560.1 - 8.7e-06 26.0 3.7 0.095 13.1 0.4 3.0 2 1 0 2 2 2 2 Elongation factor Tu domain 2 Roc PF08477.13 GAX15560.1 - 0.0003 21.0 0.1 0.076 13.2 0.0 2.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX15560.1 - 0.013 15.1 0.0 0.043 13.4 0.0 1.9 1 0 0 1 1 1 0 Ras family Dynamin_N PF00350.23 GAX15560.1 - 0.16 12.0 4.6 11 6.0 0.0 3.7 3 1 1 4 4 4 0 Dynamin family Peptidase_M24 PF00557.24 GAX15561.1 - 2.1e-52 177.9 0.0 2.8e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_21 PF05050.12 GAX15562.1 - 5e-09 36.4 0.0 9.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Thioredoxin PF00085.20 GAX15563.1 - 8.7e-24 83.5 0.1 1.1e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 GAX15563.1 - 3.1e-06 27.0 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX15563.1 - 5.1e-06 26.9 0.1 0.00021 21.7 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GAX15563.1 - 1.9e-05 24.2 0.1 2.2e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 GAX15563.1 - 6.3e-05 22.9 0.0 7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 GAX15563.1 - 8.4e-05 22.8 0.0 0.0023 18.2 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 GAX15563.1 - 0.0033 17.3 0.1 0.0044 16.9 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 GAX15563.1 - 0.0043 17.2 0.1 0.012 15.8 0.1 1.9 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_7 PF13899.6 GAX15563.1 - 0.0087 16.2 0.1 0.02 15.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAX15563.1 - 0.015 15.3 0.1 0.044 13.8 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin domain Redoxin PF08534.10 GAX15563.1 - 0.017 14.8 0.1 0.033 13.9 0.1 1.5 1 1 1 2 2 2 0 Redoxin DUF1947 PF09183.10 GAX15563.1 - 0.037 14.3 0.1 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF929 PF06053.11 GAX15563.1 - 0.072 12.4 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) RVT_2 PF07727.14 GAX15565.1 - 2.8e-45 154.9 0.1 4.6e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX15565.1 - 9.5e-07 29.0 0.4 2.6e-06 27.6 0.4 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 GAX15565.1 - 0.13 12.2 0.0 0.5 10.3 0.0 2.0 1 0 0 1 1 1 0 GAG-pre-integrase domain HMG_box_2 PF09011.10 GAX15567.1 - 3.8e-05 24.2 0.1 0.096 13.3 0.1 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 GAX15567.1 - 7.8e-05 23.0 0.7 0.22 12.0 0.0 2.7 3 0 0 3 3 3 2 HMG (high mobility group) box Rhomboid_SP PF12595.8 GAX15567.1 - 0.11 11.8 0.5 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Rhomboid serine protease LRR_8 PF13855.6 GAX15568.1 - 3.8e-14 52.2 9.7 0.00012 21.8 0.3 4.9 2 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAX15568.1 - 3.4e-10 40.0 11.7 0.12 12.8 0.0 5.9 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX15568.1 - 1e-05 25.4 6.3 11 7.0 0.0 7.6 8 0 0 8 8 8 1 Leucine Rich Repeat LRRNT_2 PF08263.12 GAX15568.1 - 0.034 14.4 2.5 0.1 12.9 2.5 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 GAX15568.1 - 0.043 13.3 1.4 1.1 8.7 0.1 2.7 2 1 1 3 3 3 0 Leucine-rich repeat 2-oxoacid_dh PF00198.23 GAX15569.1 - 2.1e-46 158.3 0.0 2.6e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX15569.1 - 1.8e-17 62.9 0.2 3.8e-17 61.9 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAX15569.1 - 6.8e-13 48.7 1.6 1.2e-12 48.0 0.3 2.2 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAX15569.1 - 0.14 12.1 0.0 0.8 9.6 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like DEC-1_N PF04625.13 GAX15569.1 - 5.2 6.0 15.1 8.6 5.3 15.1 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Metallophos PF00149.28 GAX15571.1 - 5.4e-12 46.7 0.0 9.7e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase rRNA_methylase PF06962.12 GAX15572.1 - 3.3e-21 75.7 0.0 7.4e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_25 PF13649.6 GAX15572.1 - 0.011 16.4 0.0 0.026 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAX15572.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 GAX15572.1 - 0.02 14.9 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SAM_MT PF04445.13 GAX15572.1 - 0.031 13.7 0.0 0.068 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase NIR_SIR PF01077.22 GAX15574.1 - 1.3e-50 171.0 0.0 9.5e-44 148.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 GAX15574.1 - 6.1e-28 96.5 0.1 3.2e-14 52.5 0.0 2.9 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Peptidase_S8 PF00082.22 GAX15575.1 - 7.2e-37 127.3 8.0 9.6e-36 123.5 8.0 2.0 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAX15575.1 - 0.063 14.0 0.1 1.5 9.5 0.1 2.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 LPMO_10 PF03067.15 GAX15576.1 - 3.5e-32 112.6 1.1 4.8e-32 112.2 1.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Toxin_12 PF07740.12 GAX15576.1 - 0.019 15.7 10.0 0.019 15.7 10.0 2.9 3 0 0 3 3 3 0 Ion channel inhibitory toxin SAP130_C PF16014.5 GAX15576.1 - 4.3 6.3 9.2 6.2 5.8 9.2 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Cwf_Cwc_15 PF04889.12 GAX15577.1 - 0.64 9.7 6.3 0.94 9.2 6.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EF-hand_4 PF12763.7 GAX15578.1 - 3.3e-15 55.9 0.0 3.4e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Macoilin PF09726.9 GAX15578.1 - 0.54 8.8 12.1 0.48 8.9 0.1 2.1 2 0 0 2 2 2 0 Macoilin family Herpes_BLRF2 PF05812.12 GAX15578.1 - 1.1 9.4 12.5 0.078 13.1 7.0 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein TMPIT PF07851.13 GAX15578.1 - 4.4 6.4 24.6 0.4 9.9 5.9 2.4 2 1 0 2 2 2 0 TMPIT-like protein Med15_fungi PF05397.12 GAX15578.1 - 5.8 7.2 8.6 8.7 6.7 3.1 2.9 2 0 0 2 2 2 0 Mediator complex subunit 15 SHMT PF00464.19 GAX15581.1 - 3e-170 566.1 0.0 3.8e-170 565.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 GAX15581.1 - 0.00017 20.9 0.0 0.00038 19.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II FliT PF05400.13 GAX15581.1 - 0.0034 18.2 3.2 0.1 13.4 0.2 3.0 3 0 0 3 3 3 1 Flagellar protein FliT DUF2401 PF10287.9 GAX15582.1 - 0.052 13.1 0.4 0.052 13.1 0.4 3.7 3 1 0 3 3 3 0 Putative TOS1-like glycosyl hydrolase (DUF2401) CX9C PF16860.5 GAX15582.1 - 0.44 10.6 30.6 0.48 10.5 0.2 5.7 5 0 0 5 5 5 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 GAX15583.1 - 0.0038 17.3 3.2 1.4 9.1 0.0 2.8 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 GAX15583.1 - 0.044 13.8 2.5 0.044 13.8 2.5 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DnaA_N PF11638.8 GAX15583.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 DnaA N-terminal domain CHCH PF06747.13 GAX15584.1 - 0.0018 18.3 3.3 0.9 9.7 0.9 2.7 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 GAX15584.1 - 0.29 11.2 13.0 0.36 10.9 1.8 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 GAX15584.1 - 1.6 9.0 9.3 3.8 7.8 5.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) PHD20L1_u1 PF16660.5 GAX15585.1 - 0.015 16.1 1.3 0.026 15.3 1.3 1.3 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 Pet191_N PF10203.9 GAX15585.1 - 5.7 7.3 8.9 8.2 6.8 1.3 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Aromatic_hydrox PF11723.8 GAX15587.1 - 0.043 13.3 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase LRR_8 PF13855.6 GAX15588.1 - 5.5e-26 90.1 43.1 8.5e-06 25.4 0.2 7.2 4 3 1 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GAX15588.1 - 1.6e-19 69.6 39.1 0.0032 17.8 2.6 9.3 6 3 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX15588.1 - 1e-08 34.5 26.6 3 8.7 0.1 12.1 12 1 0 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX15588.1 - 0.055 13.5 23.8 2.2 8.6 0.0 9.1 10 0 0 10 10 10 0 Leucine Rich repeat LRR_9 PF14580.6 GAX15588.1 - 1.9 8.0 5.2 11 5.4 0.0 3.6 3 1 1 4 4 4 0 Leucine-rich repeat NUP50 PF08911.11 GAX15589.1 - 4.9e-08 33.5 13.2 4.9e-08 33.5 13.2 4.3 2 2 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 GAX15589.1 - 1e-05 25.8 0.0 3.6e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 RanBP1 domain Bac_globin PF01152.21 GAX15590.1 - 0.0069 16.5 0.1 0.034 14.3 0.1 1.9 1 1 0 1 1 1 1 Bacterial-like globin Vhr1 PF04001.13 GAX15590.1 - 0.16 12.3 0.1 0.39 11.0 0.1 1.6 2 0 0 2 2 2 0 Transcription factor Vhr1 CX9C PF16860.5 GAX15591.1 - 0.00083 19.3 0.8 0.00083 19.3 0.8 7.9 8 1 0 8 8 8 5 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3072 PF11272.8 GAX15591.1 - 0.035 14.0 0.3 19 5.2 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3072) SAM_decarbox PF01536.16 GAX15592.1 - 1.4e-92 310.5 0.0 1.7e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase AdoMet_dc PF02675.15 GAX15592.1 - 0.0038 17.4 0.0 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine decarboxylase DUF3051 PF11252.8 GAX15592.1 - 0.11 12.2 0.0 11 5.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3051) 5_nucleotid PF05761.14 GAX15593.1 - 2.1e-146 488.5 2.0 2.4e-146 488.2 2.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family LPMO_10 PF03067.15 GAX15594.1 - 4.8e-28 99.1 1.2 7.5e-28 98.5 1.2 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Toxin_12 PF07740.12 GAX15594.1 - 0.0032 18.1 7.5 0.0032 18.1 7.5 3.7 3 0 0 3 3 3 2 Ion channel inhibitory toxin Toxin_7 PF05980.12 GAX15594.1 - 0.0054 16.9 9.6 0.0054 16.9 9.6 3.2 3 0 0 3 3 3 2 Toxin 7 ubiquitin PF00240.23 GAX15595.1 - 2.2e-12 46.5 0.0 3.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX15595.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Jagunal PF07086.12 GAX15595.1 - 0.021 14.9 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis DUF2407 PF10302.9 GAX15595.1 - 0.16 12.5 0.0 0.48 11.0 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain GST_N_2 PF13409.6 GAX15596.1 - 6.7e-11 42.3 0.1 4.2e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX15596.1 - 2.1e-08 34.1 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX15596.1 - 1.8e-07 31.4 0.0 4.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAX15596.1 - 4.4e-05 23.6 0.0 8.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAX15596.1 - 9.1e-05 22.7 0.1 0.002 18.4 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAX15596.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain eIF2_C PF09173.11 GAX15597.1 - 9.5e-36 121.9 0.1 2.7e-35 120.5 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GAX15597.1 - 7.7e-24 84.3 1.2 6.4e-23 81.3 1.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAX15597.1 - 2.2e-10 40.8 1.3 2.2e-10 40.8 1.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX15597.1 - 0.00077 19.5 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase CxC7 PF18866.1 GAX15597.1 - 0.0034 17.5 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 2 CxC7 like cysteine cluster associated with KDZ transposases RsgA_GTPase PF03193.16 GAX15597.1 - 0.0075 16.2 0.4 0.4 10.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GAX15597.1 - 0.14 12.2 0.1 0.42 10.7 0.1 1.9 1 1 0 1 1 1 0 Dynamin family PHF5 PF03660.14 GAX15599.1 - 4e-47 158.7 15.4 4.4e-47 158.6 15.4 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 GAX15599.1 - 1.7 6.4 10.6 1.8 6.4 10.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cyclin_N PF00134.23 GAX15600.1 - 1.9e-07 30.9 0.1 5.2e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain GTP_EFTU PF00009.27 GAX15601.1 - 1.4e-46 158.5 0.1 2.5e-46 157.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX15601.1 - 3e-15 56.0 0.0 6.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX15601.1 - 1.3e-08 35.1 0.1 3.4e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX15601.1 - 0.00011 22.3 0.1 0.00027 21.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 GAX15601.1 - 0.0082 16.2 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II FeoB_N PF02421.18 GAX15601.1 - 0.013 15.1 0.1 0.064 12.8 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 GAX15601.1 - 0.077 13.2 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L10 PF00466.20 GAX15602.1 - 1.6e-21 76.3 0.0 3.1e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 GAX15602.1 - 2.8e-21 75.3 0.3 4.7e-21 74.6 0.3 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 GAX15602.1 - 1.5e-10 41.5 2.4 1.5e-10 41.5 2.4 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein HTH_Tnp_Tc3_1 PF11427.8 GAX15602.1 - 0.022 14.6 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Tc3 transposase Pro_isomerase PF00160.21 GAX15603.1 - 1.1e-07 32.3 0.1 2.1e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2681 PF10883.8 GAX15603.1 - 0.049 14.0 1.2 0.12 12.8 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CALCOCO1 PF07888.11 GAX15603.1 - 0.11 11.4 6.9 0.16 10.8 6.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like UPF0242 PF06785.11 GAX15603.1 - 0.16 12.1 4.7 0.25 11.4 4.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C4H2 PF10146.9 GAX15603.1 - 0.18 12.1 2.1 0.29 11.4 2.1 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4600 PF15372.6 GAX15603.1 - 0.24 11.8 7.0 0.48 10.9 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Snapin_Pallidin PF14712.6 GAX15603.1 - 0.79 10.2 5.7 0.57 10.6 2.9 2.0 1 1 2 3 3 3 0 Snapin/Pallidin HIP1_clath_bdg PF16515.5 GAX15603.1 - 1.4 9.6 7.9 2.7 8.6 7.9 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tub PF01167.18 GAX15604.1 - 1.3e-16 61.1 0.0 2e-16 60.5 0.0 1.3 1 1 0 1 1 1 1 Tub family Ribosomal_60s PF00428.19 GAX15605.1 - 5.3e-07 30.1 3.4 8.1e-07 29.6 3.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pap_E4 PF02711.14 GAX15606.1 - 1.9 9.5 7.8 0.22 12.5 1.2 2.2 2 1 0 2 2 2 0 E4 protein FTZ PF03867.14 GAX15607.1 - 1.7 8.1 11.9 0.35 10.4 5.6 2.0 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region EF-hand_7 PF13499.6 GAX15608.1 - 3.9e-08 33.6 2.9 0.0034 17.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX15608.1 - 9.9e-07 27.9 5.6 0.00011 21.5 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAX15608.1 - 1.6e-06 27.3 1.5 0.00074 18.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX15608.1 - 2.1e-06 27.2 1.6 0.0049 16.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAX15608.1 - 0.00038 20.2 2.2 0.02 14.7 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair DUF1664 PF07889.12 GAX15608.1 - 0.029 14.4 1.1 0.05 13.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 GAX15608.1 - 0.55 8.8 2.9 0.84 8.2 2.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Endonuc_Holl PF10107.9 GAX15608.1 - 1.4 8.7 4.3 3.1 7.7 4.3 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase UPF0449 PF15136.6 GAX15608.1 - 8.5 6.9 9.6 1.5 9.3 5.6 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Cor1 PF04803.12 GAX15608.1 - 9.2 6.5 17.9 1.3 9.2 12.9 1.9 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Ank_4 PF13637.6 GAX15610.1 - 8.2e-08 32.6 0.1 0.00096 19.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX15610.1 - 3.5e-07 30.7 0.0 7.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX15610.1 - 4e-05 23.7 0.0 0.06 13.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 GAX15610.1 - 6.6e-05 23.1 0.0 0.00021 21.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX15610.1 - 0.00078 19.8 0.1 0.51 10.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GAX15611.1 - 0.0016 19.0 0.0 0.0033 18.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX15611.1 - 0.015 15.8 0.0 18 6.3 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Glyco_hydro38C2 PF17677.1 GAX15611.1 - 0.037 14.1 0.8 0.12 12.5 0.3 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain FMN_dh PF01070.18 GAX15612.1 - 8.8e-119 396.6 0.0 1.1e-118 396.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 GAX15612.1 - 6.2e-06 25.4 0.8 1.2e-05 24.5 0.8 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 GAX15612.1 - 1.9e-05 24.0 0.1 3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 GAX15612.1 - 0.00099 18.6 0.2 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 GAX15612.1 - 0.011 15.1 0.3 0.081 12.2 0.2 2.0 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAX15612.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 GAX15612.1 - 0.068 12.4 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF1485 PF07364.12 GAX15612.1 - 0.21 10.8 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M81 DAO PF01266.24 GAX15613.1 - 4.7e-49 167.8 0.2 5.5e-49 167.6 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX15613.1 - 5.3e-05 22.6 0.2 0.0018 17.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX15613.1 - 6e-05 22.3 1.8 0.00038 19.7 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAX15613.1 - 0.00019 21.6 0.5 0.00043 20.5 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX15613.1 - 0.00094 18.5 0.3 0.0021 17.3 0.3 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 GAX15613.1 - 0.0025 17.8 0.4 0.39 10.7 0.1 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAX15613.1 - 0.01 16.4 0.7 0.062 13.9 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX15613.1 - 0.017 14.3 1.2 0.42 9.6 1.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAX15613.1 - 0.066 12.1 1.2 1.1 8.1 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 GAX15613.1 - 0.07 12.4 0.6 0.51 9.5 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_syn PF06574.12 GAX15613.1 - 0.14 12.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 FAD synthetase 3HCDH_N PF02737.18 GAX15613.1 - 0.21 11.5 0.8 0.39 10.6 0.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAX15613.1 - 1.5 7.5 3.9 0.77 8.4 1.4 1.7 2 0 0 2 2 2 0 HI0933-like protein zf-A20 PF01754.16 GAX15614.1 - 0.0051 16.7 4.5 0.0088 16.0 4.5 1.4 1 0 0 1 1 1 1 A20-like zinc finger DUF3597 PF12200.8 GAX15614.1 - 0.087 13.4 0.7 0.11 13.0 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) PRCC PF10253.9 GAX15614.1 - 1.4 9.6 5.6 1.7 9.3 5.6 1.0 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pho88 PF10032.9 GAX15615.1 - 9.2e-26 90.2 0.2 1.3e-25 89.7 0.2 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ank_2 PF12796.7 GAX15615.1 - 5.1e-10 39.8 0.0 7e-08 32.9 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX15615.1 - 2.8e-06 27.7 0.1 0.0019 18.7 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX15615.1 - 8.8e-05 22.6 0.0 1.8 9.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX15615.1 - 9e-05 22.7 0.0 0.0016 18.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX15615.1 - 0.00037 20.8 0.1 0.82 10.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Aminotran_1_2 PF00155.21 GAX15616.1 - 7.3e-45 153.7 0.0 1.1e-44 153.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAX15616.1 - 0.005 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aldo_ket_red PF00248.21 GAX15617.1 - 5.6e-29 101.3 0.0 2e-27 96.2 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family PNK3P PF08645.11 GAX15617.1 - 5.1e-21 75.0 0.0 1e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 GAX15617.1 - 4.2e-17 62.7 0.5 2.8e-16 60.0 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX15617.1 - 0.00021 21.8 0.4 0.0018 18.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX15617.1 - 0.00028 20.2 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 GAX15617.1 - 0.0014 18.9 0.0 0.0079 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAX15617.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 GAX15617.1 - 0.042 13.4 0.1 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAX15617.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain VirE PF05272.11 GAX15617.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E Dynamin_N PF00350.23 GAX15617.1 - 0.083 12.9 0.1 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Dynamin family tRNA_lig_kinase PF08303.11 GAX15617.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_14 PF13173.6 GAX15617.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Oxidored_FMN PF00724.20 GAX15618.1 - 1.7e-75 254.4 0.0 2e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ubiquitin PF00240.23 GAX15618.1 - 0.048 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family TGT PF01702.18 GAX15619.1 - 3.1e-121 404.8 0.0 3.9e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pirin PF02678.16 GAX15620.1 - 1.7e-22 79.4 0.1 1.4e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Pirin Pirin_C PF05726.13 GAX15620.1 - 8.3e-18 64.7 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain COX7a PF02238.15 GAX15621.1 - 0.002 18.5 0.1 0.0027 18.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Ank_2 PF12796.7 GAX15622.1 - 1.7e-10 41.3 0.0 3.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX15622.1 - 1.6e-07 31.0 0.0 0.06 13.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAX15622.1 - 3.4e-07 30.7 0.0 9.3e-05 22.9 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX15622.1 - 2.3e-05 24.6 0.0 0.087 13.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAX15622.1 - 0.00019 21.7 0.0 0.00053 20.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) 2-oxoacid_dh PF00198.23 GAX15623.1 - 3.9e-78 262.1 0.1 5e-78 261.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX15623.1 - 7.1e-16 57.8 3.5 1.3e-15 57.0 3.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAX15623.1 - 0.03 14.2 0.7 0.03 14.2 0.7 2.7 2 1 1 3 3 3 0 Biotin-lipoyl like HlyD_3 PF13437.6 GAX15623.1 - 0.041 14.6 3.2 1.9 9.2 0.2 2.5 1 1 1 2 2 2 0 HlyD family secretion protein OTCace PF00185.24 GAX15624.1 - 3.1e-56 189.8 0.3 4.3e-54 182.8 0.1 2.4 3 0 0 3 3 3 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 GAX15624.1 - 1.3e-45 155.0 0.0 3.1e-45 153.8 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DnaJ PF00226.31 GAX15625.1 - 3.7e-06 27.0 0.5 8.1e-06 25.9 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain Adaptin_binding PF10199.9 GAX15625.1 - 0.026 15.1 0.7 0.056 14.0 0.7 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 tRNA_bind PF01588.20 GAX15626.1 - 9.3e-27 93.0 0.0 2e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 GAX15626.1 - 0.084 12.9 0.2 0.44 10.6 0.2 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ESR1_C PF12743.7 GAX15626.1 - 0.097 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal FTHFS PF01268.19 GAX15626.1 - 0.099 10.8 0.9 0.15 10.3 0.9 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase PHD PF00628.29 GAX15627.1 - 1.2e-16 60.3 19.4 1.1e-09 38.0 8.6 2.7 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 GAX15627.1 - 3.4e-05 23.3 13.2 0.0017 17.9 4.1 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING_2 PF13639.6 GAX15627.1 - 0.0019 18.5 7.6 0.0019 18.5 7.6 3.3 3 0 0 3 3 3 1 Ring finger domain zf-PHD-like PF15446.6 GAX15627.1 - 0.062 12.9 10.4 1.3 8.6 3.0 3.5 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 GAX15627.1 - 0.16 12.3 12.4 0.029 14.6 2.5 3.0 3 0 0 3 3 3 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 GAX15627.1 - 0.81 10.0 8.5 2.4 8.6 1.5 2.9 2 0 0 2 2 2 0 RING-like domain zf-RRPl_C4 PF17026.5 GAX15627.1 - 3.1 7.9 7.6 2 8.5 0.3 3.0 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type FANCL_C PF11793.8 GAX15627.1 - 6.1 7.1 16.6 0.14 12.3 5.3 3.2 3 0 0 3 3 3 0 FANCL C-terminal domain Ribosomal_L27A PF00828.19 GAX15628.1 - 2.7e-26 92.7 0.1 3.9e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 GAX15628.1 - 0.01 15.3 0.1 0.034 13.6 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein 60S L18 and 50S L18e MORN PF02493.20 GAX15629.1 - 2.4e-27 93.1 49.1 6.3e-07 28.9 0.9 8.6 7 1 0 7 7 7 7 MORN repeat DivIC PF04977.15 GAX15629.1 - 0.17 11.6 0.8 1.1 9.0 0.9 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF3292 PF11696.8 GAX15629.1 - 0.18 10.2 2.1 0.33 9.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Cgr1 PF03879.14 GAX15629.1 - 0.53 10.7 6.7 0.33 11.3 3.1 2.5 2 0 0 2 2 2 0 Cgr1 family DAAD PF18752.1 GAX15630.1 - 4.8 6.9 7.2 18 5.1 7.0 2.0 1 1 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase Hamartin PF04388.12 GAX15630.1 - 7.4 5.1 25.7 8.2 5.0 25.7 1.1 1 0 0 1 1 1 0 Hamartin protein RDD PF06271.12 GAX15631.1 - 1.1e-10 41.9 3.8 1.4e-10 41.5 3.8 1.2 1 0 0 1 1 1 1 RDD family Bac_globin PF01152.21 GAX15632.1 - 6.6e-11 42.4 0.4 1.8e-10 41.0 0.4 1.7 1 1 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 GAX15632.1 - 0.0033 17.3 0.0 0.0045 16.9 0.0 1.4 1 1 0 1 1 1 1 Protoglobin zf-RING_2 PF13639.6 GAX15634.1 - 4.3e-12 46.2 6.5 9.4e-12 45.1 6.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX15634.1 - 8.5e-12 44.6 2.3 2e-11 43.4 2.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX15634.1 - 3.6e-06 26.7 3.9 8.3e-06 25.6 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX15634.1 - 2.2e-05 24.2 6.5 0.00011 21.9 6.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX15634.1 - 6.8e-05 23.1 7.4 0.00034 20.9 7.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX15634.1 - 9.3e-05 22.3 4.3 0.00026 20.9 4.3 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX15634.1 - 0.00017 21.6 2.5 0.00017 21.6 2.5 1.8 2 0 0 2 2 1 1 RING-type zinc-finger FANCL_C PF11793.8 GAX15634.1 - 0.004 17.3 5.1 0.013 15.7 5.1 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAX15634.1 - 0.042 13.7 5.2 0.084 12.7 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX15634.1 - 0.072 13.0 7.4 0.17 11.7 7.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GAX15634.1 - 0.21 11.3 5.4 0.62 9.7 5.4 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAX15634.1 - 0.34 11.0 10.7 3.7 7.7 10.7 2.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TetR_C_15 PF17918.1 GAX15635.1 - 0.059 14.1 0.3 0.18 12.6 0.2 1.8 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF89 PF01937.19 GAX15636.1 - 2.6e-77 260.2 0.2 3e-77 260.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 MCD PF05292.11 GAX15637.1 - 1.8e-64 217.8 0.0 6.6e-64 216.0 0.0 1.9 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain DUF922 PF06037.11 GAX15637.1 - 0.051 13.4 1.1 0.1 12.4 1.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) EMP24_GP25L PF01105.24 GAX15638.1 - 1.4e-20 74.0 0.0 1.6e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NUDIX PF00293.28 GAX15639.1 - 3.7e-07 30.2 0.0 7.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF3669 PF12417.8 GAX15639.1 - 0.032 14.4 0.1 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Zinc finger protein LRR_8 PF13855.6 GAX15640.1 - 2.2e-17 62.6 14.4 7.9e-06 25.5 0.1 5.7 2 2 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 GAX15640.1 - 6.1e-16 58.3 12.6 0.001 19.4 0.3 5.5 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX15640.1 - 2e-09 36.7 8.6 2.5 9.0 0.1 7.9 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 GAX15640.1 - 0.17 12.0 3.8 69 3.9 0.2 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.6 GAX15640.1 - 0.22 11.0 0.6 1.2 8.6 0.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeat TB2_DP1_HVA22 PF03134.19 GAX15641.1 - 2.9e-26 91.2 10.1 3.2e-16 59.0 2.7 3.7 4 1 0 4 4 4 2 TB2/DP1, HVA22 family 14-3-3 PF00244.20 GAX15642.1 - 1.8e-103 344.8 1.0 2.1e-103 344.6 1.0 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 GAX15642.1 - 0.12 12.4 0.4 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Flagellar protein FlaF DrrA_P4M PF14860.6 GAX15642.1 - 0.25 11.2 1.5 0.68 9.8 0.1 2.4 2 1 1 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain TPR_19 PF14559.6 GAX15642.1 - 0.47 11.0 3.4 0.51 10.9 0.3 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4743 PF15916.5 GAX15643.1 - 7.9e-26 90.4 0.0 1.5e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 GAX15643.1 - 8.3e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Mucin PF01456.17 GAX15644.1 - 0.0058 16.6 20.3 0.011 15.7 20.3 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein PRCC PF10253.9 GAX15644.1 - 0.16 12.8 5.5 0.24 12.2 5.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 GAX15644.1 - 1.8 7.7 7.9 2.2 7.4 7.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NadA PF02445.16 GAX15645.1 - 1.4e-33 116.4 2.0 7.7e-33 113.9 0.4 2.0 2 0 0 2 2 2 1 Quinolinate synthetase A protein Ins134_P3_kin_N PF17927.1 GAX15645.1 - 0.001 19.4 0.0 0.005 17.2 0.0 2.1 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain LamB_YcsF PF03746.16 GAX15645.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 LamB/YcsF family DUF4239 PF14023.6 GAX15646.1 - 4.6e-10 39.6 0.1 6.5e-09 35.8 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4239) SBF_like PF13593.6 GAX15647.1 - 1.3e-76 257.9 14.9 1.5e-76 257.7 14.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 GAX15647.1 - 6.7e-11 42.2 3.8 1.3e-10 41.3 3.8 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family Mem_trans PF03547.18 GAX15647.1 - 1.4e-05 23.7 0.9 0.00023 19.7 0.0 2.4 1 1 0 2 2 2 1 Membrane transport protein DUF624 PF04854.14 GAX15647.1 - 0.75 9.9 6.2 4.3 7.5 0.4 3.3 2 1 0 2 2 2 0 Protein of unknown function, DUF624 CinA PF02464.17 GAX15648.1 - 0.0066 16.0 0.0 0.24 11.0 0.0 2.5 2 0 0 2 2 2 1 Competence-damaged protein HHH PF00633.23 GAX15648.1 - 0.021 14.7 0.0 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_2 PF12826.7 GAX15648.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DBINO PF13892.6 GAX15648.1 - 3 8.2 18.6 0.21 11.9 11.2 2.4 2 0 0 2 2 2 0 DNA-binding domain Pkinase PF00069.25 GAX15649.1 - 1.2e-18 67.5 0.0 2.8e-18 66.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15649.1 - 4.1e-18 65.6 0.0 5.4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pol_alpha_B_N PF08418.10 GAX15650.1 - 0.0024 17.9 3.7 0.0031 17.5 3.7 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DUF4592 PF15262.6 GAX15652.1 - 0.34 11.6 0.1 0.34 11.6 0.1 4.8 4 2 2 6 6 6 0 Domain of unknown function (DUF4592) SAP PF02037.27 GAX15653.1 - 4.8e-12 45.3 2.8 4.8e-12 45.3 2.8 1.8 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 GAX15653.1 - 0.081 12.7 0.2 0.081 12.7 0.2 3.2 5 0 0 5 5 5 0 Tho1/MOS11 C-terminal domain Apt1 PF10351.9 GAX15653.1 - 0.14 11.0 3.6 0.17 10.7 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dicty_REP PF05086.12 GAX15653.1 - 0.65 7.9 2.7 0.83 7.6 2.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC27 PF09507.10 GAX15653.1 - 0.77 9.1 23.1 0.94 8.8 23.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SRP-alpha_N PF04086.13 GAX15653.1 - 9.5 6.0 15.4 12 5.7 15.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ATG11 PF10377.9 GAX15654.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 11 ROQ_II PF18386.1 GAX15654.1 - 0.11 12.3 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Roquin II domain DUF5340 PF17275.2 GAX15655.1 - 0.32 11.2 5.4 0.13 12.4 2.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5340) Seadorna_VP6 PF07407.11 GAX15655.1 - 6.9 5.5 5.4 15 4.4 3.8 1.8 1 1 1 2 2 2 0 Seadornavirus VP6 protein DUF1995 PF09353.10 GAX15656.1 - 9.2e-31 107.4 0.1 7.1e-30 104.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) Sigma70_r1_1 PF03979.14 GAX15656.1 - 0.00017 21.6 6.7 0.00024 21.1 4.7 2.3 2 1 0 2 2 2 1 Sigma-70 factor, region 1.1 CDC37_C PF08564.10 GAX15656.1 - 0.0013 18.8 1.2 0.0031 17.6 0.2 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain POP1 PF06978.11 GAX15657.1 - 2.6 8.0 10.5 0.46 10.5 3.5 2.0 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 GtrA PF04138.14 GAX15658.1 - 0.00027 21.2 9.1 0.00037 20.7 9.1 1.2 1 0 0 1 1 1 1 GtrA-like protein Arginase PF00491.21 GAX15659.1 - 8.1e-70 235.5 0.0 1e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family ETF PF01012.21 GAX15659.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain PGAP1 PF07819.13 GAX15660.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 PGAP1-like protein RNA_pol_Rpb1_R PF05001.13 GAX15660.1 - 8.5 6.9 10.5 5.2 7.6 0.7 4.0 3 0 0 3 3 3 0 RNA polymerase Rpb1 C-terminal repeat Bombinin PF05298.11 GAX15661.1 - 0.024 14.3 0.4 0.068 12.9 0.4 1.9 1 0 0 1 1 1 0 Bombinin DUF2508 PF10704.9 GAX15661.1 - 2.4 8.4 10.0 0.11 12.7 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) PPR_2 PF13041.6 GAX15662.1 - 3.9e-33 113.4 0.1 1.6e-08 34.6 0.1 7.8 7 1 1 8 8 8 6 PPR repeat family PPR_1 PF12854.7 GAX15662.1 - 1.2e-22 79.2 2.4 0.016 14.9 0.0 9.7 10 0 0 10 10 10 6 PPR repeat PPR PF01535.20 GAX15662.1 - 3.2e-22 77.2 16.2 0.0001 22.3 0.0 10.9 12 0 0 12 12 12 5 PPR repeat PPR_3 PF13812.6 GAX15662.1 - 7.9e-16 57.9 0.0 0.0049 16.9 0.0 7.0 5 1 2 7 7 7 3 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX15662.1 - 1.3e-08 34.4 1.3 0.072 12.4 0.0 4.6 4 1 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP DUF4003 PF13170.6 GAX15662.1 - 0.054 12.9 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) DUF3696 PF12476.8 GAX15662.1 - 0.079 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) TPR_14 PF13428.6 GAX15662.1 - 0.18 12.7 6.9 16 6.6 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF349 PF03993.12 GAX15662.1 - 0.22 11.8 1.1 2.5 8.5 0.0 3.5 5 0 0 5 5 5 0 Domain of Unknown Function (DUF349) DEAD PF00270.29 GAX15663.1 - 4.6e-10 39.5 0.1 1.2e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsRBD2 PF17842.1 GAX15663.1 - 2.8e-05 24.4 0.0 0.00012 22.3 0.0 2.2 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 AAA_19 PF13245.6 GAX15663.1 - 0.0013 19.1 0.1 0.004 17.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX15663.1 - 0.0015 18.8 0.1 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.31 GAX15663.1 - 0.0041 17.5 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 GAX15663.1 - 0.026 15.2 0.0 0.088 13.5 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif DND1_DSRM PF14709.7 GAX15663.1 - 0.067 13.5 0.1 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_23 PF13476.6 GAX15663.1 - 0.22 12.0 0.0 0.22 12.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain Pro_isomerase PF00160.21 GAX15664.1 - 5.1e-24 85.3 0.0 8.3e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UCH PF00443.29 GAX15667.1 - 8.4e-46 156.5 0.0 1e-45 156.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX15667.1 - 5.8e-14 52.4 0.0 2.6e-12 47.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAX15667.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UIM PF02809.20 GAX15667.1 - 0.026 14.4 2.3 0.42 10.7 2.9 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif SNAP PF14938.6 GAX15668.1 - 6.9e-94 314.4 13.4 8e-94 314.2 13.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP NSF PF02071.20 GAX15668.1 - 0.0053 17.2 21.9 4.3 8.5 0.3 6.5 7 0 0 7 7 7 2 Aromatic-di-Alanine (AdAR) repeat TPR_MalT PF17874.1 GAX15668.1 - 0.0088 15.4 0.8 0.0088 15.4 0.8 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 GAX15668.1 - 0.024 14.9 13.2 0.037 14.3 0.5 4.7 2 1 4 6 6 6 0 Tetratricopeptide repeat DUF4071 PF13281.6 GAX15668.1 - 0.065 12.3 0.3 0.087 11.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Spatacsin_C PF14649.6 GAX15668.1 - 1 8.4 7.4 1.3 8.0 0.3 2.2 2 0 0 2 2 2 0 Spatacsin C-terminus TPR_7 PF13176.6 GAX15668.1 - 1.3 9.3 9.4 66 3.9 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 GAX15668.1 - 1.3 9.1 13.0 11 6.2 0.1 4.9 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain adh_short_C2 PF13561.6 GAX15669.1 - 2.9e-49 167.7 0.0 3.7e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX15669.1 - 9.6e-38 129.6 0.0 1.2e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX15669.1 - 4.7e-07 29.9 0.0 7.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX15669.1 - 0.0023 17.4 0.5 0.013 15.0 0.5 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cyclin_N PF00134.23 GAX15670.1 - 4.7e-22 78.1 0.0 8.8e-22 77.2 0.0 1.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX15670.1 - 1.9e-14 53.7 0.0 3.9e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zip PF02535.22 GAX15671.1 - 1.1e-42 146.5 6.2 1.3e-42 146.2 6.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.20 GAX15671.1 - 0.1 12.1 0.0 0.1 12.1 0.0 2.6 4 0 0 4 4 4 0 E1-E2 ATPase Ima1_N PF09779.9 GAX15672.1 - 0.012 16.5 0.3 0.023 15.6 0.3 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain Cytochrome_CBB3 PF13442.6 GAX15672.1 - 0.042 14.2 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III zf_UBZ PF18439.1 GAX15672.1 - 0.26 10.9 2.6 0.49 10.0 0.0 2.8 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger PMSR PF01625.21 GAX15673.1 - 4e-45 153.7 0.4 5.8e-45 153.2 0.4 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 GAX15673.1 - 0.00073 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Exo_endo_phos PF03372.23 GAX15674.1 - 2.3e-11 43.7 0.0 4.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_11 PF13414.6 GAX15675.1 - 0.0021 17.7 2.0 0.15 11.8 0.1 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 GAX15675.1 - 0.025 14.7 3.6 0.13 12.4 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Corona_NSP4_C PF16348.5 GAX15675.1 - 0.032 15.0 0.2 0.058 14.2 0.2 1.4 1 0 0 1 1 1 0 Coronavirus nonstructural protein 4 C-terminus TPR_12 PF13424.6 GAX15675.1 - 0.11 12.9 1.3 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX15675.1 - 0.12 12.2 4.2 0.14 12.1 0.9 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX15675.1 - 0.14 12.3 1.6 3.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15675.1 - 0.26 11.2 0.1 0.26 11.2 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zinc_ribbon_6 PF14599.6 GAX15676.1 - 1.7e-16 60.0 0.2 1.7e-16 60.0 0.2 4.0 3 1 1 4 4 3 1 Zinc-ribbon zf-CHY PF05495.12 GAX15676.1 - 5e-14 52.5 17.3 5e-14 52.5 17.3 5.0 2 2 0 2 2 1 1 CHY zinc finger zf-RING_2 PF13639.6 GAX15676.1 - 1.5e-08 34.8 7.7 1.5e-08 34.8 7.7 5.1 5 1 0 5 5 4 1 Ring finger domain zf-RING_5 PF14634.6 GAX15676.1 - 9.3e-06 25.5 6.2 9.3e-06 25.5 6.2 5.6 4 3 2 7 7 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAX15676.1 - 1.4e-05 24.8 6.5 1.4e-05 24.8 6.5 5.3 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX15676.1 - 0.00015 21.7 1.0 0.00015 21.7 1.0 4.9 5 1 1 6 6 5 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX15676.1 - 0.00028 20.7 6.5 0.00028 20.7 6.5 5.8 3 1 2 5 5 3 2 Zinc finger, C3HC4 type (RING finger) Rubredoxin_2 PF18073.1 GAX15676.1 - 0.032 14.0 0.3 0.032 14.0 0.3 6.8 7 1 0 7 7 7 0 Rubredoxin metal binding domain Rad50_zn_hook PF04423.14 GAX15676.1 - 0.067 13.0 1.0 3.7 7.5 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-WRNIP1_ubi PF18279.1 GAX15676.1 - 0.12 13.0 12.6 8 7.4 0.0 6.0 5 1 0 5 5 5 0 Werner helicase-interacting protein 1 ubiquitin-binding domain IlvGEDA_leader PF08046.11 GAX15676.1 - 2.6 7.6 4.6 6.3 6.3 4.6 1.6 1 0 0 1 1 1 0 IlvGEDA operon leader peptide XPG_I PF00867.18 GAX15677.1 - 2.8e-13 50.0 0.5 4.3e-12 46.2 0.5 2.5 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAX15677.1 - 5.6e-11 42.8 0.1 2e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 GAX15677.1 - 4.1e-05 23.2 0.0 8.5e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing Nkap_C PF06047.11 GAX15678.1 - 1.8e-44 150.0 3.5 1.8e-44 150.0 3.5 2.5 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain S1 PF00575.23 GAX15678.1 - 7.7e-13 48.6 0.3 1.9e-12 47.3 0.3 1.7 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 GAX15678.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 S1 domain Ndc1_Nup PF09531.10 GAX15678.1 - 0.64 8.6 13.2 0.96 8.1 13.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 GAX15678.1 - 0.74 6.9 14.7 1 6.4 14.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Miga PF10265.9 GAX15678.1 - 2.9 6.8 13.6 5.8 5.8 13.6 1.5 1 0 0 1 1 1 0 Mitoguardin PAP1 PF08601.10 GAX15678.1 - 4.1 7.0 23.4 0.36 10.5 18.8 1.6 2 0 0 2 2 2 0 Transcription factor PAP1 Mem_trans PF03547.18 GAX15678.1 - 7.3 4.9 5.5 9.5 4.5 5.5 1.3 1 0 0 1 1 1 0 Membrane transport protein PseudoU_synth_2 PF00849.22 GAX15679.1 - 1.3e-13 51.3 0.1 2.3e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Cyclin_N PF00134.23 GAX15681.1 - 4.4e-09 36.1 0.0 1.1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain WW PF00397.26 GAX15681.1 - 8.7e-09 35.3 3.6 1.8e-08 34.3 3.6 1.5 1 0 0 1 1 1 1 WW domain Cyclin PF08613.11 GAX15681.1 - 9.5e-08 32.6 0.0 1.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin CLN3 PF02487.17 GAX15682.1 - 3.2e-69 233.9 9.1 4e-69 233.6 9.1 1.1 1 0 0 1 1 1 1 CLN3 protein MucB_RseB PF03888.14 GAX15683.1 - 0.097 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 MucB/RseB N-terminal domain Metallophos PF00149.28 GAX15684.1 - 4.1e-05 24.2 0.0 5.2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IMS PF00817.20 GAX15685.1 - 2.6e-34 118.4 0.2 4.5e-34 117.6 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 GAX15685.1 - 0.047 14.0 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Put_Phosphatase PF06888.12 GAX15686.1 - 3.3e-40 137.9 0.0 3.7e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 GAX15686.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX15686.1 - 0.053 13.6 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DHHC PF01529.20 GAX15687.1 - 1.9e-11 44.2 3.2 2.8e-11 43.6 0.0 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase Syntaxin-6_N PF09177.11 GAX15688.1 - 6e-12 46.0 4.8 1.3e-11 44.9 0.4 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal DUF5446 PF17522.2 GAX15688.1 - 0.0081 16.3 1.9 0.012 15.8 0.1 2.2 3 0 0 3 3 2 1 Family of unknown function (DUF5446) DUF1664 PF07889.12 GAX15688.1 - 0.0098 15.9 7.3 0.35 10.9 0.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) KxDL PF10241.9 GAX15688.1 - 0.016 15.5 1.6 0.016 15.5 1.6 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein SlyX PF04102.12 GAX15688.1 - 0.021 15.4 2.5 0.021 15.4 2.5 3.2 2 2 0 2 2 2 0 SlyX SNARE PF05739.19 GAX15688.1 - 0.049 13.6 0.4 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 SNARE domain V-SNARE PF05008.15 GAX15688.1 - 0.1 13.0 6.1 5.1 7.6 0.9 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 GAX15688.1 - 0.11 12.4 6.3 4 7.4 1.3 3.0 2 1 0 2 2 2 0 Sec20 DUF948 PF06103.11 GAX15688.1 - 0.32 11.3 6.5 3.9 7.8 0.4 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 GAX15688.1 - 1.3 8.2 6.9 0.51 9.5 0.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF1043 PF06295.12 GAX15688.1 - 2.1 8.4 7.5 6.2 6.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DNA_ligase_aden PF01653.18 GAX15689.1 - 0.0027 16.8 0.1 0.23 10.5 0.0 2.1 2 0 0 2 2 2 2 NAD-dependent DNA ligase adenylation domain SHOCT PF09851.9 GAX15689.1 - 0.0059 16.3 2.0 1.3 8.8 0.3 2.6 2 0 0 2 2 2 2 Short C-terminal domain Sel_put PF04328.13 GAX15689.1 - 0.034 14.2 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Selenoprotein, putative TF_Zn_Ribbon PF08271.12 GAX15689.1 - 0.19 11.3 5.5 0.22 11.1 0.6 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 GAX15689.1 - 0.72 9.8 4.9 0.71 9.8 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain GTP_EFTU PF00009.27 GAX15690.1 - 1.4e-24 86.8 0.1 2.2e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAX15690.1 - 9.2e-07 28.9 0.0 2.4e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX15690.1 - 1.9e-05 24.6 0.7 0.091 12.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 GAX15690.1 - 0.006 16.8 0.1 3.6 7.8 0.1 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GAX15690.1 - 0.021 14.6 0.1 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 GAX15690.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 GAX15690.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Dynamin family DHHC PF01529.20 GAX15691.1 - 3.3e-13 49.9 0.0 3.3e-13 49.9 0.0 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase HA PF03457.14 GAX15692.1 - 2e-67 223.4 34.6 7.9e-15 54.9 2.5 5.6 5 0 0 5 5 5 5 Helicase associated domain TUDOR_5 PF18359.1 GAX15692.1 - 3.7e-07 29.7 2.3 0.0061 16.2 0.1 2.7 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Titin_Z PF09042.11 GAX15692.1 - 0.035 14.1 0.9 0.11 12.5 0.9 1.8 1 0 0 1 1 1 0 Titin Z AT_hook PF02178.19 GAX15692.1 - 0.095 12.6 4.3 0.29 11.1 4.3 1.9 1 0 0 1 1 1 0 AT hook motif DUF4960 PF16324.5 GAX15692.1 - 5.7 6.4 11.3 2.9 7.4 0.3 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4960) DHHC PF01529.20 GAX15693.1 - 6.9e-15 55.3 3.8 1.5e-14 54.3 0.6 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Pro_isomerase PF00160.21 GAX15694.1 - 2.2e-07 31.3 0.0 4.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BRE1 PF08647.11 GAX15694.1 - 0.82 9.8 5.8 5.4 7.2 1.3 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1350 PF07082.11 GAX15695.1 - 1.6e-42 145.5 0.0 2.1e-34 119.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1350) Hydrolase_4 PF12146.8 GAX15695.1 - 0.17 11.2 0.1 0.44 9.8 0.1 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Ank_2 PF12796.7 GAX15696.1 - 5.8e-11 42.8 0.1 1e-10 42.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX15696.1 - 1.4e-10 41.2 0.0 2.1e-06 27.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX15696.1 - 1e-08 35.3 0.0 0.00057 20.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAX15696.1 - 4.3e-08 33.5 0.0 0.065 13.8 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX15696.1 - 1.4e-07 31.2 0.1 0.058 14.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Gly_transf_sug PF04488.15 GAX15697.1 - 6.4e-09 36.3 0.0 2.4e-08 34.5 0.0 2.1 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX15697.1 - 3.4e-06 26.6 0.0 7.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein PI3_PI4_kinase PF00454.27 GAX15699.1 - 7.3e-69 232.3 0.0 1.2e-68 231.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAX15699.1 - 2.9e-52 178.0 1.8 1.5e-51 175.6 1.8 2.2 1 1 0 1 1 1 1 FAT domain DUF3385 PF11865.8 GAX15699.1 - 5.7e-44 149.9 0.0 1.2e-41 142.3 0.0 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 GAX15699.1 - 1.8e-27 95.7 0.1 1.2e-26 93.0 0.1 2.5 1 1 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 GAX15699.1 - 2.1e-14 53.0 0.9 6.8e-14 51.4 0.9 2.0 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 GAX15699.1 - 2.6e-09 37.3 11.4 0.0019 18.5 0.1 7.3 5 2 2 7 7 7 2 HEAT repeats HEAT PF02985.22 GAX15699.1 - 6.9e-09 35.2 22.3 0.23 11.8 0.2 9.3 8 0 0 8 8 7 4 HEAT repeat TPR_19 PF14559.6 GAX15699.1 - 0.029 14.9 2.6 0.037 14.5 0.0 2.7 3 0 0 3 3 1 0 Tetratricopeptide repeat Tti2 PF10521.9 GAX15699.1 - 0.15 11.6 0.8 19 4.7 0.0 4.1 5 0 0 5 5 5 0 Tti2 family HEAT_EZ PF13513.6 GAX15699.1 - 0.18 12.4 19.7 20 5.8 0.0 8.8 9 0 0 9 9 9 0 HEAT-like repeat TPR_14 PF13428.6 GAX15699.1 - 0.39 11.7 5.1 6.2 7.9 0.0 5.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF393 PF04134.12 GAX15700.1 - 3.3e-26 92.8 0.0 4.9e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF393 KOW PF00467.29 GAX15701.1 - 0.0064 16.4 2.0 0.017 15.1 2.0 1.7 1 0 0 1 1 1 1 KOW motif ANAPC_CDC26 PF10471.9 GAX15702.1 - 6.8 7.6 7.2 3.7 8.5 2.9 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Amino_oxidase PF01593.24 GAX15703.1 - 1.3e-56 192.8 0.0 1.5e-56 192.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX15703.1 - 1.2e-14 54.3 0.1 2.6e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX15703.1 - 2.9e-06 26.6 0.1 0.00062 19.0 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain MCRA PF06100.11 GAX15703.1 - 8.1e-05 21.6 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 GAX15703.1 - 0.00014 21.2 0.0 0.00064 19.0 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX15703.1 - 0.0029 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX15703.1 - 0.0038 16.0 0.7 0.0073 15.1 0.7 1.4 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 GAX15703.1 - 0.004 16.5 0.0 0.03 13.6 0.0 2.2 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAX15703.1 - 0.0043 16.2 0.2 0.0083 15.2 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GAX15703.1 - 0.0075 16.8 0.1 0.16 12.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 GAX15703.1 - 0.018 14.9 0.1 0.044 13.7 0.0 1.6 2 0 0 2 2 1 0 Rossmann-like domain DAO PF01266.24 GAX15703.1 - 0.03 13.9 0.1 0.27 10.8 0.1 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAX15703.1 - 0.033 13.4 0.1 0.084 12.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.21 GAX15703.1 - 0.16 11.3 0.2 6.1 6.1 0.1 2.2 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.18 GAX15703.1 - 0.33 10.8 0.7 0.58 10.0 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RTC PF01137.21 GAX15704.1 - 1.1e-74 250.4 0.1 1.3e-74 250.2 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 GAX15704.1 - 2.4e-14 53.7 0.1 4.7e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pkinase PF00069.25 GAX15705.1 - 6.4e-62 209.3 0.0 9.5e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15705.1 - 2.9e-45 154.6 0.0 4.7e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX15705.1 - 4.4e-06 25.7 0.0 7.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAX15705.1 - 0.072 12.0 0.1 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Myb_DNA-binding PF00249.31 GAX15706.1 - 3.1e-06 27.3 0.1 7e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF438 PF04282.13 GAX15706.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF438) WD40 PF00400.32 GAX15707.1 - 2.8e-17 62.8 14.4 0.001 19.9 0.9 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15707.1 - 2.5e-05 24.5 0.0 1.3 9.4 0.0 4.0 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX15707.1 - 0.0017 17.4 0.2 0.11 11.4 0.0 2.7 2 2 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GAX15707.1 - 0.12 11.1 0.0 0.88 8.2 0.0 2.2 2 1 1 3 3 3 0 Nup133 N terminal like Thioredoxin_8 PF13905.6 GAX15709.1 - 3.8e-23 81.6 0.0 8e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like fn3 PF00041.21 GAX15709.1 - 2.7e-08 34.0 0.3 0.007 16.7 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Thioredoxin PF00085.20 GAX15709.1 - 1.4e-06 28.2 0.0 9.7e-06 25.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Tissue_fac PF01108.17 GAX15709.1 - 1.6e-06 27.9 0.2 0.067 13.0 0.1 2.3 2 0 0 2 2 2 2 Tissue factor Pur_ac_phosph_N PF16656.5 GAX15709.1 - 2.4e-06 28.0 3.4 0.0039 17.7 1.8 2.7 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Thioredoxin_2 PF13098.6 GAX15709.1 - 3.4e-05 24.3 0.0 8.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAX15709.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX15709.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 Redoxin DUF3823_C PF18003.1 GAX15709.1 - 0.074 13.8 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) Thioredoxin_7 PF13899.6 GAX15709.1 - 0.18 12.0 0.1 1.1 9.5 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like SET PF00856.28 GAX15711.1 - 1.3e-11 45.1 0.0 2.4e-06 28.1 0.0 4.1 2 2 0 2 2 2 2 SET domain PMBR PF09373.10 GAX15711.1 - 0.097 12.9 0.8 0.65 10.3 0.2 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat SET PF00856.28 GAX15712.1 - 2.2e-17 64.0 0.0 1.9e-09 38.1 0.0 4.4 2 2 0 2 2 2 2 SET domain WD40 PF00400.32 GAX15713.1 - 3e-53 176.6 21.3 4.8e-10 39.9 0.1 8.2 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15713.1 - 6.6e-16 58.4 0.8 0.014 15.7 0.0 4.8 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX15713.1 - 1.2e-11 44.0 6.3 9.5e-05 21.2 0.2 4.5 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX15713.1 - 0.00085 18.4 9.6 0.12 11.3 1.5 3.6 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 GAX15713.1 - 0.0029 17.6 0.2 4.6 7.3 0.0 4.0 3 2 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PAS PF00989.25 GAX15715.1 - 0.00072 19.5 0.0 0.0023 17.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold HLH PF00010.26 GAX15715.1 - 0.0047 16.9 0.3 0.011 15.7 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC74_C PF14917.6 GAX15715.1 - 0.0088 16.6 1.1 0.023 15.2 0.3 2.1 2 0 0 2 2 2 1 Coiled coil protein 74, C terminal Peptidase_M15_3 PF08291.11 GAX15715.1 - 0.031 14.4 0.2 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Peptidase M15 PAS_9 PF13426.7 GAX15715.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 PAS domain DUF4239 PF14023.6 GAX15715.1 - 0.44 10.2 1.9 0.95 9.1 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) ApoLp-III PF07464.11 GAX15716.1 - 0.0013 18.8 11.7 0.0013 18.8 11.7 3.1 4 0 0 4 4 4 1 Apolipophorin-III precursor (apoLp-III) B2 PF11473.8 GAX15716.1 - 0.0028 17.4 1.4 3.2 7.6 0.0 3.5 2 1 1 3 3 3 2 RNA binding protein B2 Serine_rich PF08824.10 GAX15716.1 - 0.045 13.8 4.7 4.2 7.4 0.1 3.2 4 0 0 4 4 4 0 Serine rich protein interaction domain RmuC PF02646.16 GAX15716.1 - 0.057 12.5 0.1 0.057 12.5 0.1 3.3 3 1 1 4 4 4 0 RmuC family GIT1_C PF12205.8 GAX15716.1 - 0.15 12.2 3.1 0.63 10.2 2.8 2.3 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Prominin PF05478.11 GAX15716.1 - 0.15 10.0 1.3 0.41 8.5 1.3 1.7 1 0 0 1 1 1 0 Prominin MCPsignal PF00015.21 GAX15716.1 - 0.17 11.7 13.5 0.13 12.1 0.5 3.4 3 1 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DDE_Tnp_IS240 PF13610.6 GAX15716.1 - 0.19 12.0 4.3 13 6.0 0.1 3.5 3 1 0 4 4 4 0 DDE domain Dna2 PF08696.11 GAX15716.1 - 0.62 9.8 4.8 0.88 9.3 1.0 3.0 3 2 2 5 5 5 0 DNA replication factor Dna2 DUF948 PF06103.11 GAX15716.1 - 2.1 8.7 17.6 0.85 9.9 3.7 4.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4404 PF14357.6 GAX15716.1 - 5.2 7.8 9.8 2.9 8.6 1.3 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) E1-E2_ATPase PF00122.20 GAX15717.1 - 4.6e-52 176.2 0.3 9.8e-52 175.1 0.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX15717.1 - 3.8e-41 140.8 1.9 7.7e-41 139.8 1.9 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAX15717.1 - 9e-20 71.9 0.1 4.1e-17 63.2 0.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX15717.1 - 1.6e-14 53.7 0.0 4.2e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAX15717.1 - 5e-07 29.7 1.0 1.9e-05 24.5 1.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC2_membrane PF01061.24 GAX15718.1 - 3.9e-28 98.3 19.0 6.3e-28 97.6 19.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX15718.1 - 4.9e-18 66.0 0.0 8.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAX15718.1 - 8.9e-05 22.5 0.1 0.00017 21.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 GAX15718.1 - 0.027 14.3 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAX15718.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX15718.1 - 0.086 12.6 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 GAX15718.1 - 0.14 11.2 17.6 0.23 10.5 17.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_16 PF13191.6 GAX15718.1 - 0.16 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DEPP PF15343.6 GAX15718.1 - 0.18 11.9 0.0 1.5 8.8 0.0 2.4 2 1 0 2 2 2 0 Decidual protein induced by progesterone family AAA_18 PF13238.6 GAX15718.1 - 0.19 12.2 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 GAX15719.1 - 4.4e-34 117.7 18.7 4.4e-34 117.7 18.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAX15719.1 - 1.1e-21 77.8 0.0 1.6e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX15719.1 - 8.8e-12 44.8 10.7 1.5e-11 44.1 10.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAX15719.1 - 2.1e-05 24.5 0.0 5.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GAX15719.1 - 0.02 15.4 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GAX15719.1 - 0.022 14.6 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 GAX15719.1 - 0.031 13.3 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 GAX15719.1 - 0.033 14.6 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 GAX15719.1 - 0.035 13.5 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAX15719.1 - 0.044 13.9 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX15719.1 - 0.062 13.1 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 GAX15719.1 - 0.095 12.0 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 GAX15719.1 - 0.1 12.8 0.0 0.49 10.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAX15719.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX15719.1 - 0.15 12.0 0.1 5 7.1 0.1 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 GAX15719.1 - 0.21 11.3 0.1 27 4.3 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Voldacs PF03517.13 GAX15720.1 - 5.2e-07 29.9 4.5 4.5e-06 26.8 1.2 2.7 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling mRNA_cap_enzyme PF01331.19 GAX15721.1 - 6.3e-24 84.9 0.0 1.2e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_triPase PF02940.15 GAX15721.1 - 1.9e-11 44.1 0.0 5.2e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_C PF03919.15 GAX15721.1 - 3.9e-06 27.5 0.2 6.3e-05 23.6 0.0 2.6 2 1 1 3 3 3 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 GAX15721.1 - 0.037 13.7 0.0 5.3 6.6 0.0 2.4 1 1 1 2 2 2 0 ATP dependent DNA ligase domain MutS_I PF01624.20 GAX15722.1 - 9e-13 48.5 0.0 1.9e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_V PF00488.21 GAX15722.1 - 5e-05 23.4 0.0 9.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V DNA_pol_A PF00476.20 GAX15722.1 - 0.0055 15.8 0.1 0.0089 15.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family A AAA_29 PF13555.6 GAX15722.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyoxalase_6 PF18029.1 GAX15723.1 - 0.13 13.1 0.0 11 6.9 0.1 2.5 2 1 0 2 2 2 0 Glyoxalase-like domain Methyltransf_25 PF13649.6 GAX15725.1 - 4.4e-13 49.7 0.0 1.1e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX15725.1 - 3.7e-11 43.0 0.0 5.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAX15725.1 - 3.1e-10 40.6 0.0 9.9e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX15725.1 - 5e-08 32.9 0.1 1.1e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX15725.1 - 3.5e-06 27.0 0.2 6.5e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX15725.1 - 9.7e-06 25.5 0.0 2.4e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX15725.1 - 4.9e-05 22.9 0.1 7.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAX15725.1 - 8.7e-05 23.2 0.1 0.00021 22.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 GAX15725.1 - 0.0002 20.8 0.1 0.00029 20.2 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 GAX15725.1 - 0.00028 19.9 0.1 0.00035 19.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 GAX15725.1 - 0.0008 19.4 0.1 0.002 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX15725.1 - 0.0081 15.9 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 GAX15725.1 - 0.0084 17.1 0.1 0.03 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX15725.1 - 0.01 15.2 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 GAX15725.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TehB PF03848.14 GAX15725.1 - 0.019 14.4 1.1 0.071 12.5 1.1 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 GAX15725.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 GAX15725.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Glyco_trans_1_4 PF13692.6 GAX15726.1 - 3.9e-24 85.6 0.0 7.8e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX15726.1 - 9.4e-22 77.3 0.0 1.5e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX15726.1 - 8.1e-15 55.2 0.1 1.5e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAX15726.1 - 2.5e-05 24.8 0.0 5.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX15726.1 - 0.016 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 ATP-synt_ab PF00006.25 GAX15727.1 - 1e-05 25.3 1.2 5.9e-05 22.8 1.1 2.3 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 GAX15727.1 - 9.8e-05 22.7 0.0 0.00031 21.0 0.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Peptidase_C97 PF05903.14 GAX15729.1 - 3.6e-22 78.8 0.0 1.4e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 PPPDE putative peptidase domain Pkinase_Tyr PF07714.17 GAX15730.1 - 3.5e-58 196.9 0.0 5.3e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX15730.1 - 1.6e-50 172.0 0.0 2.8e-49 167.9 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Haspin_kinase PF12330.8 GAX15730.1 - 0.0043 16.1 0.0 0.01 14.8 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain OSTbeta PF15048.6 GAX15730.1 - 0.01 16.0 0.1 0.026 14.6 0.0 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Trp_oprn_chp PF09534.10 GAX15730.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1350 PF07082.11 GAX15731.1 - 9.2e-43 146.3 0.0 3.9e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1350) DUF1725 PF08333.11 GAX15731.1 - 0.3 10.8 0.8 0.63 9.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Ank_5 PF13857.6 GAX15732.1 - 2.7e-12 46.7 0.1 1e-07 32.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX15732.1 - 4.7e-11 43.1 0.2 8.2e-11 42.3 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX15732.1 - 5.7e-09 36.0 0.1 0.00057 20.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAX15732.1 - 8e-08 32.7 0.0 0.0071 16.9 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX15732.1 - 1.8e-07 30.9 0.1 0.015 15.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Gly_transf_sug PF04488.15 GAX15733.1 - 1.5e-08 35.2 0.1 7.6e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX15733.1 - 1.4e-05 24.7 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein PI3_PI4_kinase PF00454.27 GAX15735.1 - 1.4e-68 231.4 0.0 2.4e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAX15735.1 - 5.8e-52 177.0 4.2 9.2e-51 173.1 4.2 2.4 1 1 0 1 1 1 1 FAT domain DUF3385 PF11865.8 GAX15735.1 - 6.7e-43 146.4 0.0 8.3e-41 139.6 0.0 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 GAX15735.1 - 4.4e-27 94.4 0.5 3.2e-26 91.6 0.5 2.5 1 1 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 GAX15735.1 - 2.4e-14 52.8 0.9 6.8e-14 51.4 0.9 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 GAX15735.1 - 2.2e-07 31.2 14.1 0.0097 16.3 0.2 7.3 5 2 2 7 7 7 2 HEAT repeats HEAT PF02985.22 GAX15735.1 - 8.7e-07 28.7 24.0 0.23 11.8 0.2 8.9 8 0 0 8 8 8 3 HEAT repeat TPR_19 PF14559.6 GAX15735.1 - 0.0095 16.4 0.0 0.044 14.3 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 GAX15735.1 - 0.033 14.7 20.1 20 5.8 0.0 9.2 10 1 1 11 11 11 0 HEAT-like repeat TPR_14 PF13428.6 GAX15735.1 - 0.063 14.1 2.8 2.2 9.3 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF393 PF04134.12 GAX15736.1 - 2.4e-26 93.3 0.0 3e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 KOW PF00467.29 GAX15737.1 - 0.0045 16.9 2.0 0.012 15.6 2.0 1.8 1 0 0 1 1 1 1 KOW motif Amino_oxidase PF01593.24 GAX15738.1 - 2.7e-56 191.8 0.0 3.1e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX15738.1 - 1.2e-14 54.3 0.1 2.6e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX15738.1 - 3.3e-06 26.4 0.1 0.00062 19.0 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain MCRA PF06100.11 GAX15738.1 - 7.5e-05 21.7 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 GAX15738.1 - 0.00014 21.2 0.0 0.00065 19.0 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX15738.1 - 0.0027 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX15738.1 - 0.0038 16.0 0.7 0.0073 15.1 0.7 1.4 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 GAX15738.1 - 0.0039 16.5 0.1 0.03 13.6 0.0 2.2 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAX15738.1 - 0.0039 16.3 0.2 0.0083 15.2 0.2 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GAX15738.1 - 0.0074 16.8 0.1 0.16 12.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 GAX15738.1 - 0.019 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain DAO PF01266.24 GAX15738.1 - 0.024 14.3 0.1 0.27 10.8 0.1 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAX15738.1 - 0.03 13.6 0.1 0.084 12.1 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.21 GAX15738.1 - 0.11 11.8 0.2 6.1 6.1 0.1 2.2 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.18 GAX15738.1 - 0.33 10.8 0.7 0.58 10.0 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RTC PF01137.21 GAX15739.1 - 2.3e-75 252.6 0.0 2.7e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 GAX15739.1 - 1.6e-14 54.2 0.1 3e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pkinase PF00069.25 GAX15740.1 - 2.4e-62 210.7 0.0 3.7e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15740.1 - 1e-45 156.1 0.0 1.6e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX15740.1 - 4.4e-06 25.7 0.0 7.8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAX15740.1 - 0.074 12.0 0.2 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Myb_DNA-binding PF00249.31 GAX15741.1 - 3e-06 27.3 0.1 6.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF438 PF04282.13 GAX15741.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF438) WD40 PF00400.32 GAX15742.1 - 2.7e-17 62.8 14.3 0.0011 19.7 0.8 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15742.1 - 2.6e-05 24.5 0.0 1.3 9.4 0.0 4.0 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX15742.1 - 0.0017 17.4 0.2 0.11 11.5 0.0 2.7 2 2 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GAX15742.1 - 0.12 11.1 0.0 0.88 8.2 0.0 2.2 2 1 1 3 3 3 0 Nup133 N terminal like C8 PF08742.11 GAX15743.1 - 0.026 15.0 0.2 0.038 14.4 0.2 1.3 1 0 0 1 1 1 0 C8 domain Thioredoxin_8 PF13905.6 GAX15744.1 - 1.4e-22 79.8 0.0 2.6e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 GAX15744.1 - 1.1e-06 28.6 0.0 8.2e-06 25.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX15744.1 - 0.00018 21.9 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAX15744.1 - 0.00041 20.3 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family fn3 PF00041.21 GAX15744.1 - 0.0005 20.4 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 Fibronectin type III domain Tissue_fac PF01108.17 GAX15744.1 - 0.00091 19.1 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 2 Tissue factor Pur_ac_phosph_N PF16656.5 GAX15744.1 - 0.0019 18.8 0.5 0.52 10.9 0.3 2.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Redoxin PF08534.10 GAX15744.1 - 0.0025 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin DUF3823_C PF18003.1 GAX15744.1 - 0.035 14.8 0.1 0.073 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) Thioredoxin_9 PF14595.6 GAX15744.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin SET PF00856.28 GAX15746.1 - 2.3e-12 47.6 0.0 9.4e-06 26.1 0.0 4.0 3 1 2 5 5 5 3 SET domain Thioredoxin PF00085.20 GAX15747.1 - 1.8e-19 69.6 0.0 2e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 GAX15747.1 - 0.00014 21.7 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 GAX15747.1 - 0.00025 20.8 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAX15747.1 - 0.00037 20.4 0.0 0.0005 20.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 GAX15747.1 - 0.00091 19.7 0.0 0.0016 18.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX15747.1 - 0.0049 17.0 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAX15747.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.6 GAX15747.1 - 0.0069 16.7 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 GAX15747.1 - 0.076 12.6 0.6 0.13 11.9 0.4 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) SET PF00856.28 GAX15748.1 - 4.4e-17 63.0 0.0 5.2e-08 33.5 0.0 4.5 2 2 0 2 2 2 2 SET domain WD40 PF00400.32 GAX15749.1 - 8.6e-54 178.3 23.5 4.8e-10 39.9 0.1 8.3 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15749.1 - 5.3e-16 58.7 2.3 0.009 16.3 0.1 5.0 2 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX15749.1 - 9e-12 44.4 6.9 0.00011 21.0 0.3 4.6 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX15749.1 - 0.00031 19.8 9.0 0.09 11.7 1.9 3.6 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 GAX15749.1 - 0.0027 17.7 0.1 4.8 7.3 0.0 4.1 3 2 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 GAX15749.1 - 0.072 13.0 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PhyH PF05721.13 GAX15750.1 - 0.08 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) HLH PF00010.26 GAX15751.1 - 0.049 13.6 0.4 0.12 12.3 0.4 1.8 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain Peptidase_M15_3 PF08291.11 GAX15751.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase M15 DDE_Tnp_IS240 PF13610.6 GAX15752.1 - 0.00083 19.6 1.1 0.36 11.0 0.2 3.4 2 1 0 2 2 2 1 DDE domain DUF948 PF06103.11 GAX15752.1 - 0.0034 17.6 11.0 0.2 11.9 4.4 4.3 2 1 2 4 4 4 2 Bacterial protein of unknown function (DUF948) GIT1_C PF12205.8 GAX15752.1 - 0.011 15.9 3.0 0.68 10.1 0.7 2.8 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term RmuC PF02646.16 GAX15752.1 - 0.011 14.8 0.1 0.011 14.8 0.1 3.3 3 1 2 5 5 5 0 RmuC family ApoLp-III PF07464.11 GAX15752.1 - 0.015 15.4 10.1 0.015 15.4 10.1 3.3 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) B2 PF11473.8 GAX15752.1 - 0.055 13.3 4.2 5 7.0 0.0 3.4 3 1 1 4 4 4 0 RNA binding protein B2 Prominin PF05478.11 GAX15752.1 - 0.073 11.0 1.2 0.16 9.9 1.2 1.6 1 0 0 1 1 1 0 Prominin Serine_rich PF08824.10 GAX15752.1 - 0.12 12.4 1.5 4.6 7.2 0.0 2.9 3 0 0 3 3 3 0 Serine rich protein interaction domain ING PF12998.7 GAX15752.1 - 0.64 10.6 3.4 2.6 8.7 0.2 3.3 3 1 1 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding Dna2 PF08696.11 GAX15752.1 - 0.82 9.4 3.6 1.2 8.9 0.9 2.6 3 1 1 4 4 4 0 DNA replication factor Dna2 Laminin_II PF06009.12 GAX15752.1 - 3.7 7.6 12.2 6.1 6.9 2.7 3.8 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 GAX15752.1 - 4 7.5 10.7 1.8 8.6 2.3 3.5 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GAX15752.1 - 7.8 6.5 8.9 4.5 7.3 1.1 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus E1-E2_ATPase PF00122.20 GAX15753.1 - 3.7e-51 173.2 0.2 8.4e-51 172.1 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX15753.1 - 4.8e-41 140.5 2.4 9.7e-41 139.5 2.4 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAX15753.1 - 6e-20 72.4 0.0 2.3e-17 64.0 0.0 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX15753.1 - 2.2e-14 53.3 0.0 5.6e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAX15753.1 - 7.5e-07 29.1 1.2 2e-05 24.5 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC2_membrane PF01061.24 GAX15754.1 - 6.2e-30 104.2 16.9 6.2e-30 104.2 16.9 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAX15754.1 - 9.4e-10 39.1 0.0 1.1e-08 35.7 0.0 2.1 1 1 1 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX15754.1 - 4.6e-05 22.7 12.3 7.7e-05 22.0 12.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1127 PF06568.11 GAX15754.1 - 0.069 12.9 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) ABC2_membrane PF01061.24 GAX15755.1 - 3.1e-34 118.2 19.9 3.1e-34 118.2 19.9 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAX15755.1 - 3.5e-21 76.2 0.0 5.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX15755.1 - 2.1e-11 43.5 12.3 3.6e-11 42.8 12.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAX15755.1 - 2.2e-05 24.4 0.0 6.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GAX15755.1 - 0.021 15.3 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAX15755.1 - 0.022 13.8 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_21 PF13304.6 GAX15755.1 - 0.024 14.5 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX15755.1 - 0.031 13.7 0.0 0.085 12.3 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAX15755.1 - 0.045 13.8 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX15755.1 - 0.046 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GAX15755.1 - 0.072 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX15755.1 - 0.11 12.8 0.0 0.56 10.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAX15755.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAX15755.1 - 0.14 11.4 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 GAX15755.1 - 0.17 11.9 0.0 5.5 7.0 0.0 3.1 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) Voldacs PF03517.13 GAX15756.1 - 2.8e-07 30.7 5.3 9.6e-07 29.0 0.9 2.6 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling mRNA_triPase PF02940.15 GAX15757.1 - 1.9e-12 47.4 0.0 5.4e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_enzyme PF01331.19 GAX15757.1 - 1e-08 35.2 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DUF2808 PF10989.8 GAX15757.1 - 0.15 12.0 1.7 0.22 11.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) MutS_V PF00488.21 GAX15758.1 - 2.9e-37 128.5 0.0 5.2e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 GAX15758.1 - 8.6e-13 48.5 0.0 1.8e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain I DNA_pol_A PF00476.20 GAX15758.1 - 0.00079 18.6 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A GIY-YIG PF01541.24 GAX15758.1 - 0.0066 16.7 0.0 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain Methyltransf_25 PF13649.6 GAX15760.1 - 4.4e-13 49.7 0.0 1.1e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX15760.1 - 4e-11 42.9 0.0 5.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAX15760.1 - 3.2e-10 40.5 0.0 9.9e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX15760.1 - 5.2e-08 32.8 0.1 1.1e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX15760.1 - 3.6e-06 27.0 0.2 6.5e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX15760.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX15760.1 - 5e-05 22.9 0.1 7.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAX15760.1 - 8.4e-05 23.3 0.0 0.00021 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX15760.1 - 0.00021 20.7 0.1 0.0003 20.2 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 GAX15760.1 - 0.00033 19.7 0.1 0.00048 19.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 GAX15760.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX15760.1 - 0.0081 15.9 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 GAX15760.1 - 0.0086 17.1 0.1 0.03 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX15760.1 - 0.011 15.1 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 GAX15760.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TehB PF03848.14 GAX15760.1 - 0.019 14.4 1.1 0.071 12.5 1.1 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 GAX15760.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 GAX15760.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Glyco_trans_1_4 PF13692.6 GAX15761.1 - 4.4e-24 85.4 0.0 9.1e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX15761.1 - 8.3e-22 77.5 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX15761.1 - 1.1e-14 54.8 0.1 1.8e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAX15761.1 - 1.9e-05 25.1 0.0 4.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX15761.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 ATP-synt_ab PF00006.25 GAX15762.1 - 1.4e-05 24.9 1.0 7.9e-05 22.4 0.9 2.3 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 GAX15762.1 - 0.00038 20.8 0.2 0.0013 19.0 0.1 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain Herpes_UL21 PF03252.13 GAX15762.1 - 0.12 11.1 0.1 0.2 10.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL21 Peptidase_C97 PF05903.14 GAX15764.1 - 9.2e-22 77.5 0.0 2.2e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 PPPDE putative peptidase domain Pkinase_Tyr PF07714.17 GAX15765.1 - 3.3e-58 197.0 0.0 4.7e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX15765.1 - 2e-50 171.6 0.0 2.6e-49 168.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 GAX15765.1 - 0.0043 16.1 0.0 0.01 14.8 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain OSTbeta PF15048.6 GAX15765.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.6 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Trp_oprn_chp PF09534.10 GAX15765.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) F5_F8_type_C PF00754.25 GAX15766.1 - 9.1e-09 35.5 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 GAX15766.1 - 0.00081 19.4 0.1 0.0029 17.6 0.1 2.0 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Metallophos PF00149.28 GAX15767.1 - 5.6e-39 134.8 0.2 7.1e-39 134.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAX15767.1 - 4.7e-17 62.2 0.6 1.1e-16 60.9 0.3 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF3903 PF13043.6 GAX15767.1 - 0.17 11.7 0.2 0.37 10.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) Nop25 PF09805.9 GAX15768.1 - 0.006 17.1 4.0 0.012 16.1 4.0 1.4 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) CoaE PF01121.20 GAX15768.1 - 0.053 13.2 1.3 0.094 12.4 0.2 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase Pannexin_like PF12534.8 GAX15768.1 - 0.41 9.7 5.7 2.3 7.2 0.1 2.1 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 tRNA-synt_1 PF00133.22 GAX15769.1 - 3e-193 643.4 0.0 3.8e-193 643.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAX15769.1 - 7.3e-31 107.2 0.0 1.3e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAX15769.1 - 4.1e-20 71.9 0.0 1.9e-11 43.4 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAX15769.1 - 0.0051 16.3 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAX15769.1 - 0.0071 15.7 0.0 0.099 12.0 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 GAX15769.1 - 0.061 13.2 1.3 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Mito_carr PF00153.27 GAX15770.1 - 1.8e-40 136.8 1.2 5.4e-14 51.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_2 PF07719.17 GAX15771.1 - 3.5e-09 36.1 11.6 0.00066 19.6 1.3 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15771.1 - 9.6e-09 34.7 9.8 7.9e-05 22.3 1.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX15771.1 - 2.6e-07 30.7 10.7 0.00017 21.7 3.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX15771.1 - 1.5e-06 28.1 4.5 0.0091 16.3 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat STI1 PF17830.1 GAX15771.1 - 1.7e-06 27.8 13.2 0.002 18.0 1.8 2.8 3 0 0 3 3 3 2 STI1 domain TPR_16 PF13432.6 GAX15771.1 - 5e-06 27.1 10.9 5.2e-05 23.8 7.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX15771.1 - 0.00011 22.7 7.2 0.0059 17.3 2.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX15771.1 - 0.00013 21.5 3.5 0.14 11.9 0.5 3.4 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 GAX15771.1 - 0.00067 20.1 7.5 0.0024 18.3 4.5 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat RLL PF10036.9 GAX15771.1 - 0.031 14.1 4.9 0.075 12.9 2.5 2.2 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein TPR_8 PF13181.6 GAX15771.1 - 0.054 13.7 0.2 0.054 13.7 0.2 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX15771.1 - 0.11 13.2 6.0 26 5.7 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NACHT_N PF17100.5 GAX15771.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase TPR_12 PF13424.6 GAX15771.1 - 0.11 12.8 9.5 0.12 12.6 4.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat OAD_gamma PF04277.13 GAX15771.1 - 1.7 9.3 6.0 41 4.9 0.1 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4337 PF14235.6 GAX15771.1 - 9.1 6.4 10.7 11 6.1 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) NDK PF00334.19 GAX15772.1 - 9e-39 132.6 0.0 1e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UIM PF02809.20 GAX15773.1 - 4.3e-05 23.1 3.5 0.12 12.4 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif FGGY_N PF00370.21 GAX15774.1 - 2.6e-24 86.1 0.0 5.5e-24 85.1 0.0 1.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAX15774.1 - 1.4e-21 77.2 0.3 2.6e-21 76.2 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 GAX15774.1 - 0.2 9.8 0.0 0.3 9.2 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Chorismate_bind PF00425.18 GAX15775.1 - 2.7e-62 210.6 0.1 5.5e-62 209.6 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 GAX15775.1 - 9.4e-40 136.4 0.0 1.8e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAX15775.1 - 3.8e-11 43.4 0.0 6.9e-09 36.0 0.0 3.3 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAX15775.1 - 4.8e-09 36.3 0.0 1.3e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 SAP PF02037.27 GAX15775.1 - 0.0031 17.2 0.0 0.0076 16.0 0.0 1.7 1 0 0 1 1 1 1 SAP domain IMPa_N_2 PF18650.1 GAX15775.1 - 0.23 10.7 0.4 0.61 9.3 0.0 1.9 2 0 0 2 2 2 0 Immunomodulating metalloprotease N-terminal domain FSA_C PF10479.9 GAX15775.1 - 0.58 8.2 4.6 0.88 7.6 4.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NIF PF03031.18 GAX15777.1 - 1.1e-14 54.4 0.0 1.8e-13 50.5 0.1 2.3 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 GAX15777.1 - 1.1e-06 28.9 0.0 2.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAX15777.1 - 0.0004 20.3 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 GAX15777.1 - 0.021 15.1 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain CFTR_R PF14396.6 GAX15777.1 - 0.035 13.7 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain BRCT_2 PF16589.5 GAX15777.1 - 0.18 12.2 0.0 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain BEX PF04538.12 GAX15777.1 - 0.38 11.4 5.9 1.1 9.9 5.9 1.7 1 0 0 1 1 1 0 Brain expressed X-linked like family DUF2358 PF10184.9 GAX15778.1 - 1.1e-08 35.4 0.0 1.6e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 GAX15778.1 - 0.001 19.6 0.0 0.0019 18.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 GAX15778.1 - 0.0078 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase RAP PF08373.10 GAX15779.1 - 2.2e-12 46.9 0.0 4.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 GAX15779.1 - 0.031 14.2 0.2 0.21 11.6 0.0 2.5 3 1 0 3 3 3 0 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 GAX15779.1 - 0.043 14.0 0.0 0.19 11.9 0.0 2.2 1 1 0 1 1 1 0 REase_MTES_1575 Got1 PF04178.12 GAX15780.1 - 5e-28 97.8 16.8 8.9e-28 97.0 16.8 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Ribul_P_3_epim PF00834.19 GAX15781.1 - 7e-87 289.9 0.3 8.4e-87 289.7 0.3 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 GAX15781.1 - 4.3e-07 29.9 0.0 0.00035 20.4 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 GAX15781.1 - 0.0019 17.7 0.1 0.0045 16.5 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 GAX15781.1 - 0.042 13.0 0.1 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 GAX15781.1 - 0.051 12.9 0.4 0.44 9.9 0.1 2.3 2 1 0 2 2 2 0 Thiamine monophosphate synthase Glyoxalase_6 PF18029.1 GAX15781.1 - 0.13 13.1 0.1 13 6.6 0.0 2.3 1 1 1 2 2 2 0 Glyoxalase-like domain DUF4148 PF13663.6 GAX15781.1 - 0.28 11.4 1.7 0.9 9.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF4516 PF14990.6 GAX15781.1 - 3.4 7.5 4.6 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) MFS_1 PF07690.16 GAX15782.1 - 9.4e-30 103.7 25.8 3.9e-29 101.7 25.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 GAX15782.1 - 0.0018 16.8 6.1 0.0036 15.8 6.1 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector TLD PF07534.16 GAX15783.1 - 2.9e-12 47.0 0.0 7.3e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 TLD cNMP_binding PF00027.29 GAX15783.1 - 0.16 12.0 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Band_7 PF01145.25 GAX15784.1 - 1.2e-29 103.6 0.4 1.2e-29 103.6 0.4 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 GAX15784.1 - 7.9e-17 61.1 0.4 1.7e-16 60.0 0.4 1.6 1 0 0 1 1 1 1 C-terminal region of band_7 SR-25 PF10500.9 GAX15786.1 - 1.2e-05 25.0 12.5 1.6e-05 24.6 12.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 GAX15786.1 - 0.013 15.7 8.0 0.015 15.5 8.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF3435 PF11917.8 GAX15786.1 - 0.013 14.4 4.4 0.017 14.1 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) PNGaseA PF12222.8 GAX15786.1 - 0.079 11.8 1.5 0.095 11.5 1.5 1.0 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A TAF1D PF15333.6 GAX15786.1 - 0.1 12.4 6.7 0.14 11.9 6.7 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF4603 PF15376.6 GAX15786.1 - 0.1 10.0 12.1 0.12 9.7 12.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Herpes_pp85 PF04637.12 GAX15786.1 - 0.19 10.1 1.8 0.23 9.8 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) STAC2_u1 PF16664.5 GAX15786.1 - 0.27 11.7 10.3 0.36 11.3 10.3 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 NAM-associated PF14303.6 GAX15786.1 - 0.3 11.8 11.0 0.49 11.1 11.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Presenilin PF01080.17 GAX15786.1 - 0.36 9.6 3.0 0.39 9.4 3.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4061 PF13270.6 GAX15786.1 - 0.51 10.7 5.2 0.8 10.1 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) FAM199X PF15814.5 GAX15786.1 - 0.59 9.1 7.5 0.75 8.8 7.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X TCP PF03634.13 GAX15786.1 - 2.1 8.9 12.7 2.9 8.5 12.7 1.1 1 0 0 1 1 1 0 TCP family transcription factor Ferlin_C PF16165.5 GAX15786.1 - 5.9 6.8 7.6 8.8 6.3 7.6 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Hist_deacetyl PF00850.19 GAX15787.1 - 1.5e-50 172.5 0.4 2.6e-50 171.6 0.4 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Peptidase_M54 PF07998.11 GAX15787.1 - 0.058 13.4 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M54 ERG4_ERG24 PF01222.17 GAX15788.1 - 5.4e-136 453.8 8.3 1.1e-135 452.8 8.3 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ydc2-catalyt PF09159.10 GAX15789.1 - 0.0031 17.3 1.2 0.0034 17.1 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 DUF1353 PF07087.11 GAX15789.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) CBM9_2 PF16011.5 GAX15789.1 - 0.049 13.3 0.8 0.084 12.6 0.8 1.3 1 0 0 1 1 1 0 Carbohydrate-binding family 9 XRCC1_N PF01834.16 GAX15790.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 XRCC1 N terminal domain F5_F8_type_C PF00754.25 GAX15790.1 - 0.036 14.2 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain AAA_22 PF13401.6 GAX15791.1 - 1.8e-12 47.7 0.0 4.9e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAX15791.1 - 2.7e-10 40.8 0.2 9.9e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAX15791.1 - 5.7e-08 32.4 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein NB-ARC PF00931.22 GAX15791.1 - 0.0019 17.4 0.0 0.0049 16.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 GAX15791.1 - 0.0024 18.2 0.2 0.0098 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 GAX15791.1 - 0.013 15.6 0.2 0.036 14.2 0.2 1.7 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 GAX15791.1 - 0.027 14.9 0.0 0.15 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 GAX15791.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 GAX15791.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain 2OG-FeII_Oxy_3 PF13640.6 GAX15792.1 - 0.049 14.5 0.0 0.071 14.0 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_M8 PF01457.16 GAX15793.1 - 3.5e-54 184.4 3.9 1e-53 182.9 3.7 1.7 1 1 0 1 1 1 1 Leishmanolysin Apocytochr_F_N PF16639.5 GAX15794.1 - 0.034 14.4 0.1 0.086 13.1 0.1 1.6 1 0 0 1 1 1 0 Apocytochrome F, N-terminal TPR_14 PF13428.6 GAX15795.1 - 2.4e-11 43.4 3.3 0.032 15.1 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX15795.1 - 9.9e-08 31.5 12.4 1 9.6 0.2 6.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX15795.1 - 1.7e-07 31.7 3.6 0.39 11.4 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX15795.1 - 6.6e-06 25.9 0.7 16 6.0 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX15795.1 - 4.3e-05 23.9 1.7 5.1 7.7 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX15795.1 - 0.0084 16.2 3.5 3.8 7.7 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX15795.1 - 0.0089 16.6 4.1 5.2 8.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX15795.1 - 0.15 12.5 1.4 60 4.4 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX15795.1 - 0.17 12.2 11.0 1.7 9.0 0.2 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat AP3D1 PF06375.11 GAX15795.1 - 0.27 11.4 2.9 0.45 10.7 2.9 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Popeye PF04831.13 GAX15796.1 - 3.5e-10 40.2 0.0 4.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 GAX15796.1 - 1.2e-05 25.3 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Imp-YgjV PF10688.9 GAX15796.1 - 0.035 13.9 0.6 0.051 13.4 0.6 1.2 1 0 0 1 1 1 0 Bacterial inner membrane protein OAM_dimer PF16554.5 GAX15796.1 - 0.15 12.6 0.1 0.3 11.6 0.1 1.4 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase RIBIOP_C PF04950.12 GAX15797.1 - 8.9e-102 340.4 0.0 1.8e-101 339.4 0.0 1.5 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAX15797.1 - 1.5e-08 34.6 0.0 4.3e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain UCH PF00443.29 GAX15798.1 - 0.0036 16.8 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ran_BP1 PF00638.18 GAX15799.1 - 8.3e-41 139.1 0.3 1.4e-40 138.3 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain PH_15 PF17339.2 GAX15799.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 PH domain WH1 PF00568.23 GAX15799.1 - 0.074 13.0 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 WH1 domain TRAPPC10 PF12584.8 GAX15800.1 - 0.083 12.6 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 Arrestin_C PF02752.22 GAX15800.1 - 0.13 12.7 0.2 0.41 11.1 0.2 1.8 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Ribosomal_L7Ae PF01248.26 GAX15801.1 - 2.3e-20 72.1 2.6 2.8e-20 71.9 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HSF_DNA-bind PF00447.17 GAX15802.1 - 9.7e-23 80.6 1.0 1.2e-22 80.4 0.0 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding Sugar_tr PF00083.24 GAX15803.1 - 5.7e-21 74.9 9.3 1.5e-20 73.5 9.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX15803.1 - 1.9e-20 73.1 24.4 2.2e-20 72.9 22.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily EF_TS PF00889.19 GAX15804.1 - 7.3e-45 153.1 0.4 8.7e-45 152.9 0.4 1.1 1 0 0 1 1 1 1 Elongation factor TS DUF5305 PF17231.2 GAX15805.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TFIIA PF03153.13 GAX15805.1 - 1.1 9.2 20.4 2.3 8.1 6.7 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit MgtE PF01769.16 GAX15806.1 - 3.9e-18 66.0 11.0 9.6e-18 64.8 10.2 1.9 2 0 0 2 2 2 1 Divalent cation transporter MPS2 PF17060.5 GAX15806.1 - 0.011 15.0 0.4 0.023 14.0 0.0 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 PKcGMP_CC PF16808.5 GAX15806.1 - 0.018 14.9 2.0 0.032 14.1 2.0 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bap31_Bap29_C PF18035.1 GAX15806.1 - 0.037 14.0 1.5 0.058 13.4 1.5 1.2 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain CCDC74_C PF14917.6 GAX15806.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal COMP PF11598.8 GAX15806.1 - 0.17 12.4 0.3 0.32 11.5 0.3 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Spermine_synth PF01564.17 GAX15807.1 - 2.3e-39 134.8 0.0 4.1e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GAX15807.1 - 3.8e-12 45.9 0.3 8.7e-11 41.5 0.0 2.9 2 1 1 3 3 3 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAX15807.1 - 0.002 18.8 0.0 0.0041 17.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX15807.1 - 0.0079 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX15807.1 - 0.051 14.3 0.0 0.13 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAX15807.1 - 0.063 13.0 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Eno-Rase_NADH_b PF12242.8 GAX15807.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GidB PF02527.15 GAX15808.1 - 1.1e-29 103.1 0.0 1.6e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 GAX15808.1 - 2.5e-08 33.9 0.0 5.4e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX15808.1 - 0.00095 19.8 0.0 0.0024 18.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX15808.1 - 0.048 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 GAX15808.1 - 0.061 13.1 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.25 GAX15810.1 - 8.6e-18 64.6 0.0 1.7e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 GAX15810.1 - 2.4e-11 43.6 11.0 6.1e-11 42.3 11.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-CRD PF17979.1 GAX15810.1 - 0.0066 16.6 2.9 0.0066 16.6 2.9 1.6 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions Abhydrolase_6 PF12697.7 GAX15810.1 - 0.09 13.4 0.3 0.49 11.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family MOZ_SAS PF01853.18 GAX15811.1 - 3.8e-78 261.2 0.5 5.5e-78 260.7 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 GAX15811.1 - 3.8e-14 52.3 0.4 1.1e-13 50.9 0.4 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 GAX15811.1 - 9e-14 50.8 0.1 2.8e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 GAX15811.1 - 0.0076 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX15811.1 - 0.03 14.6 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Importin_rep_4 PF18808.1 GAX15811.1 - 1.8 8.9 4.7 4.9 7.5 0.5 2.5 2 0 0 2 2 2 0 Importin repeat Ribosomal_S4e PF00900.20 GAX15812.1 - 3.3e-32 110.2 2.1 1.2e-31 108.4 0.8 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 GAX15812.1 - 2.4e-23 81.5 0.5 5e-23 80.5 0.0 1.8 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 GAX15812.1 - 8.9e-20 70.5 7.8 1.6e-19 69.7 7.2 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 GAX15812.1 - 6.4e-08 32.2 0.6 3.2e-07 29.9 0.0 2.4 2 1 1 3 3 3 1 S4 domain KOW PF00467.29 GAX15812.1 - 0.00024 20.9 0.5 0.00024 20.9 0.5 2.4 2 0 0 2 2 2 1 KOW motif Ribosomal_S13_N PF08069.12 GAX15813.1 - 1.5e-29 101.8 0.1 2.9e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 GAX15813.1 - 6e-16 58.4 1.1 9.5e-16 57.8 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Abhydrolase_6 PF12697.7 GAX15814.1 - 1.1e-15 58.8 0.6 1.5e-15 58.4 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX15814.1 - 2.4e-10 40.5 2.5 0.0021 17.8 0.5 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX15814.1 - 3e-08 33.2 0.4 6.3e-08 32.2 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAX15814.1 - 2.9e-05 23.9 0.1 0.076 12.7 0.1 2.3 1 1 0 2 2 2 2 PGAP1-like protein DUF915 PF06028.11 GAX15814.1 - 0.0071 15.7 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 GAX15814.1 - 0.014 14.9 0.0 0.1 12.1 0.0 2.1 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 GAX15814.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 GAX15814.1 - 0.041 13.5 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 GAX15814.1 - 0.045 13.9 0.1 0.16 12.1 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain AAA_16 PF13191.6 GAX15816.1 - 1.8e-10 41.5 0.0 5.4e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Guanylate_cyc PF00211.20 GAX15816.1 - 4.6e-09 36.2 0.1 2.7e-07 30.4 0.0 2.7 2 1 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Sulfotransfer_2 PF03567.14 GAX15817.1 - 1.3e-06 28.5 0.4 1.4e-05 25.1 0.1 2.1 2 0 0 2 2 2 1 Sulfotransferase family MMS19_N PF14500.6 GAX15818.1 - 2.8e-24 86.1 0.1 1.4e-23 83.9 0.0 2.3 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II gag_pre-integrs PF13976.6 GAX15818.1 - 0.16 11.8 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 GAG-pre-integrase domain TPT PF03151.16 GAX15819.1 - 1.8e-15 57.1 12.5 2.3e-15 56.7 12.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX15819.1 - 1.4e-10 41.5 32.9 5.4e-08 33.1 16.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX15819.1 - 2.7e-08 33.4 10.3 4.4e-08 32.7 10.1 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 GAX15819.1 - 5.7e-06 25.7 13.8 7.7e-06 25.3 13.8 1.2 1 0 0 1 1 1 1 UAA transporter family DUF2070 PF09843.9 GAX15819.1 - 0.73 8.1 16.2 0.22 9.8 9.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Aminotran_3 PF00202.21 GAX15820.1 - 1.9e-75 254.1 0.0 2.3e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAX15820.1 - 0.0038 16.5 0.0 0.007 15.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAX15820.1 - 0.032 13.4 0.0 0.2 10.8 0.0 2.0 1 1 0 1 1 1 0 Aminotransferase class I and II PA PF02225.22 GAX15821.1 - 1e-08 35.1 0.5 2.6e-08 33.8 0.5 1.7 1 0 0 1 1 1 1 PA domain 2OG-FeII_Oxy_3 PF13640.6 GAX15821.1 - 0.00096 20.0 0.0 0.0053 17.6 0.0 2.2 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily RraA-like PF03737.15 GAX15821.1 - 0.092 12.9 0.2 0.17 12.1 0.2 1.3 1 0 0 1 1 1 0 Aldolase/RraA DUF4184 PF13803.6 GAX15821.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) Pkinase PF00069.25 GAX15822.1 - 1.3e-62 211.5 0.0 1.9e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15822.1 - 1e-31 110.2 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX15822.1 - 0.0067 16.4 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX15822.1 - 0.045 12.5 0.0 0.096 11.4 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 GAX15822.1 - 0.045 12.7 0.0 0.33 9.8 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 GAX15822.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SET PF00856.28 GAX15823.1 - 3.5e-06 27.5 0.2 0.00013 22.5 0.2 2.1 1 1 0 1 1 1 1 SET domain Fas_alpha_ACP PF18325.1 GAX15823.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.4 1 1 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain Peptidase_M41 PF01434.18 GAX15824.1 - 5.9e-62 208.9 0.2 9.6e-62 208.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAX15824.1 - 6.3e-44 149.6 0.0 1.4e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX15824.1 - 1.3e-11 44.1 0.0 3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 GAX15824.1 - 0.00014 21.2 0.1 0.00026 20.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GAX15824.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX15824.1 - 0.0049 17.3 0.2 0.14 12.5 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GAX15824.1 - 0.0049 17.0 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX15824.1 - 0.005 16.9 0.1 0.03 14.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX15824.1 - 0.015 15.6 0.7 0.14 12.4 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 GAX15824.1 - 0.035 14.3 0.0 0.079 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAX15824.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsH_ext PF06480.15 GAX15824.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 FtsH Extracellular AAA_17 PF13207.6 GAX15824.1 - 0.049 14.1 0.4 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAX15824.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAX15824.1 - 0.12 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX15824.1 - 0.16 12.5 0.0 0.39 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAX15824.1 - 0.17 11.9 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_transf_92 PF01697.27 GAX15825.1 - 6.4e-19 68.6 0.0 1.9e-18 67.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GAX15825.1 - 1.6e-05 25.3 0.0 9.8e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 PDZ_6 PF17820.1 GAX15826.1 - 8.7e-05 22.3 2.2 0.00027 20.7 2.2 1.9 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX15826.1 - 0.0024 18.2 0.1 0.0054 17.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX15826.1 - 0.0047 17.2 0.3 0.018 15.3 0.3 2.0 1 1 0 1 1 1 1 PDZ domain ABC_tran PF00005.27 GAX15827.1 - 3.1e-33 115.2 0.0 5.4e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX15827.1 - 8.3e-26 91.2 1.1 1.1e-25 90.9 1.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAX15827.1 - 1.3e-06 28.0 0.0 0.00017 21.1 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX15827.1 - 7.3e-06 26.0 0.1 0.11 12.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX15827.1 - 0.0013 19.1 0.3 0.006 17.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAX15827.1 - 0.0075 16.0 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAX15827.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 GAX15827.1 - 0.039 13.7 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Ploopntkinase3 PF18751.1 GAX15827.1 - 0.058 13.3 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 GAX15827.1 - 0.073 13.3 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAX15827.1 - 0.1 11.7 0.0 0.89 8.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 GAX15827.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DUF815 PF05673.13 GAX15827.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GAX15827.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 GAX15827.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 GAX15827.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 GAX15827.1 - 0.23 11.9 0.0 0.52 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C14 PF00656.22 GAX15828.1 - 5.8e-43 147.6 3.1 7.7e-33 114.5 0.5 2.0 2 0 0 2 2 2 2 Caspase domain DUF4136 PF13590.6 GAX15828.1 - 0.16 12.6 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) DUF3507 PF12015.8 GAX15829.1 - 0.00068 19.4 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) PLDc_N PF13396.6 GAX15829.1 - 0.016 15.2 0.4 0.046 13.7 0.4 1.8 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Sulfate_transp PF00916.20 GAX15830.1 - 4.5e-113 377.9 17.1 5.9e-113 377.5 17.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAX15830.1 - 4.9e-27 93.9 0.0 1e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAX15830.1 - 4.5e-07 30.1 0.0 9.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAX15830.1 - 0.0094 16.3 1.4 0.0094 16.3 1.4 3.7 3 1 1 4 4 4 1 Molybdate transporter of MFS superfamily DUF4010 PF13194.6 GAX15830.1 - 0.35 10.5 11.9 0.036 13.8 5.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4010) EAP30 PF04157.16 GAX15831.1 - 4.4e-56 189.8 0.3 5.1e-56 189.6 0.3 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family GHMP_kinases_N PF00288.26 GAX15833.1 - 9.5e-12 45.0 1.5 9.5e-12 45.0 1.5 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAX15833.1 - 4.2e-06 27.0 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Fer2 PF00111.27 GAX15834.1 - 6.2e-07 29.3 0.2 1.2e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 GAX15834.1 - 0.0023 17.9 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain adh_short PF00106.25 GAX15835.1 - 6e-23 81.3 0.0 2.2e-19 69.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX15835.1 - 7.9e-10 38.7 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX15835.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain SLAC1 PF03595.17 GAX15836.1 - 1e-27 97.3 24.0 1e-27 97.3 24.0 2.2 2 0 0 2 2 2 1 Voltage-dependent anion channel DUF4395 PF14340.6 GAX15836.1 - 7.9e-21 74.7 10.7 7.9e-21 74.7 10.7 3.2 4 1 0 4 4 4 1 Domain of unknown function (DUF4395) Glutaredoxin PF00462.24 GAX15836.1 - 1e-12 48.1 0.2 2.4e-12 46.8 0.2 1.7 1 0 0 1 1 1 1 Glutaredoxin Hemerythrin PF01814.23 GAX15836.1 - 3.3e-05 24.5 7.5 0.00034 21.2 7.4 2.2 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Thioredoxin_2 PF13098.6 GAX15836.1 - 0.0071 16.8 0.1 0.1 13.1 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain DUF836 PF05768.14 GAX15836.1 - 0.012 16.0 0.0 0.039 14.4 0.0 1.9 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF1772 PF08592.11 GAX15836.1 - 1.4 9.2 0.0 1.4 9.2 0.0 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) NYN_YacP PF05991.11 GAX15837.1 - 8.1e-26 90.9 1.6 5.4e-13 49.2 0.0 3.3 3 1 1 4 4 4 2 YacP-like NYN domain SIT PF15330.6 GAX15837.1 - 4 7.9 4.5 1.9 9.0 0.8 2.3 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT TIL PF01826.17 GAX15839.1 - 0.3 11.4 11.1 1.1 9.5 11.1 1.7 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain C_tripleX PF02363.19 GAX15839.1 - 6.3 7.3 7.5 11 6.5 2.6 2.2 2 0 0 2 2 2 0 Cysteine rich repeat DUF202 PF02656.15 GAX15840.1 - 5.2e-17 62.0 0.4 9.6e-17 61.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) PsbU PF06514.11 GAX15841.1 - 2.6e-20 72.2 0.0 4.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 GAX15841.1 - 0.0018 18.5 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif CytB6-F_Fe-S PF08802.10 GAX15841.1 - 0.0055 16.7 0.4 0.018 15.0 0.4 1.8 1 1 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit WD40 PF00400.32 GAX15842.1 - 2.1e-35 120.1 19.0 1.8e-05 25.4 1.6 10.1 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX15842.1 - 1e-15 57.8 0.6 0.0079 16.5 0.0 7.1 3 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX15842.1 - 0.0035 17.3 0.0 0.048 13.5 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAX15842.1 - 0.014 14.0 0.0 0.61 8.5 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 GAX15842.1 - 0.035 13.4 0.9 9.5 5.4 0.2 3.2 3 1 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 GAX15842.1 - 0.092 11.7 0.3 1 8.2 0.1 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GAX15842.1 - 0.18 10.5 0.0 15 4.2 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.6 GAX15842.1 - 1.3 9.7 12.3 2.8 8.6 0.4 5.1 4 1 0 4 4 4 0 PQQ-like domain Myb_DNA-bind_6 PF13921.6 GAX15845.1 - 0.015 15.5 0.1 5.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain IGPD PF00475.18 GAX15845.1 - 0.047 14.0 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase VEFS-Box PF09733.9 GAX15847.1 - 4.7e-15 55.6 0.1 8.2e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein AMP-binding PF00501.28 GAX15848.1 - 1.4e-84 284.2 0.0 1.8e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Csa5 PF09702.10 GAX15850.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) zf-RING_2 PF13639.6 GAX15851.1 - 7.5e-12 45.4 3.2 7.5e-12 45.4 3.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX15851.1 - 2.7e-10 39.9 3.3 6e-10 38.8 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX15851.1 - 1.1e-07 31.5 0.7 2.8e-07 30.2 0.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAX15851.1 - 1.1e-07 32.0 6.8 6.8e-07 29.5 6.8 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX15851.1 - 1e-06 28.5 2.1 1e-06 28.5 2.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX15851.1 - 1.7e-06 27.9 1.4 4.7e-06 26.5 1.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX15851.1 - 5e-06 26.4 2.4 1.1e-05 25.2 2.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAX15851.1 - 1.3e-05 25.0 2.9 3.9e-05 23.4 3.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAX15851.1 - 1.6e-05 24.6 2.9 1.6e-05 24.6 2.9 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX15851.1 - 1.6e-05 24.4 2.1 4.6e-05 22.9 2.1 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAX15851.1 - 0.0051 16.8 1.1 0.015 15.4 1.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAX15851.1 - 0.0083 16.3 2.6 0.0083 16.3 2.6 2.3 2 1 0 2 2 2 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 GAX15851.1 - 0.015 15.2 4.3 0.078 12.9 4.3 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Vps39_2 PF10367.9 GAX15851.1 - 0.048 14.1 0.2 0.21 12.1 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-Nse PF11789.8 GAX15851.1 - 0.21 11.4 1.0 0.56 10.1 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 GAX15851.1 - 0.22 11.7 3.9 0.94 9.7 3.9 2.2 1 1 0 1 1 1 0 RING-variant domain Rtf2 PF04641.12 GAX15851.1 - 0.53 9.6 2.1 1.2 8.4 0.2 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3H2C3 PF17122.5 GAX15851.1 - 0.63 10.1 3.6 1.3 9.1 3.6 1.6 1 0 0 1 1 1 0 Zinc-finger BSP_II PF05432.11 GAX15851.1 - 1.9 8.1 5.5 0.24 11.1 0.4 1.9 2 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) Pan_kinase PF03309.14 GAX15852.1 - 1.1e-19 71.1 0.0 1.6e-18 67.3 0.0 2.2 1 1 0 1 1 1 1 Type III pantothenate kinase AT_hook PF02178.19 GAX15852.1 - 1e-06 27.9 51.3 0.055 13.4 2.2 6.8 6 0 0 6 6 6 6 AT hook motif LBR_tudor PF09465.10 GAX15852.1 - 0.07 12.9 0.5 0.2 11.5 0.5 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain SIS PF01380.22 GAX15853.1 - 5.2e-33 113.7 0.1 7.4e-16 58.2 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAX15853.1 - 1.8e-22 80.0 0.0 4.1e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX15853.1 - 4.1e-16 59.0 0.0 1.2e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAX15853.1 - 4.5e-06 25.8 1.2 1.7e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 Glutamine amidotransferases class-II NMT1 PF09084.11 GAX15854.1 - 3.8e-48 164.3 0.0 4.6e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 GAX15854.1 - 0.0085 15.8 0.0 0.11 12.2 0.0 2.1 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 GAX15854.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 GAX15855.1 - 3.1e-49 167.9 0.0 4e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1 PF09084.11 GAX15856.1 - 8.7e-48 163.1 0.0 1.1e-47 162.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like cobW PF02492.19 GAX15856.1 - 0.076 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GAX15858.1 - 5.1e-40 137.2 12.3 5.4e-20 72.3 0.1 3.6 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 GAX15858.1 - 5e-12 46.2 6.0 0.029 14.2 0.1 4.7 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX15858.1 - 1.5e-09 37.6 13.8 7.7e-05 22.2 0.3 4.9 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAX15858.1 - 2.8e-07 30.6 0.6 0.026 14.6 0.2 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX15858.1 - 1.3e-06 28.1 1.1 0.034 13.9 0.5 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 GAX15858.1 - 2.6e-06 27.4 0.0 0.21 11.3 0.4 3.7 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAX15858.1 - 8.5e-06 25.8 2.1 0.061 13.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 GAX15858.1 - 1.5e-05 24.3 0.2 0.084 12.0 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ABC_tran_Xtn PF12848.7 GAX15858.1 - 1.5e-05 24.9 10.9 1.5e-05 24.9 10.9 3.2 3 0 0 3 3 2 1 ABC transporter Roc PF08477.13 GAX15858.1 - 1.6e-05 25.1 0.2 0.35 11.1 0.0 3.0 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAX15858.1 - 0.00025 21.3 7.6 0.039 14.2 0.3 3.7 4 1 0 4 4 3 2 AAA domain NACHT PF05729.12 GAX15858.1 - 0.00048 20.1 6.5 0.048 13.6 1.5 3.0 3 1 0 3 3 2 2 NACHT domain MeaB PF03308.16 GAX15858.1 - 0.0005 19.1 0.1 0.13 11.2 0.0 2.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAX15858.1 - 0.0011 19.4 8.6 0.3 11.4 1.7 3.2 3 1 0 3 3 2 2 AAA ATPase domain NB-ARC PF00931.22 GAX15858.1 - 0.0019 17.5 0.1 0.42 9.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 GAX15858.1 - 0.0023 18.1 1.3 1.1 9.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 GAX15858.1 - 0.004 16.7 0.1 0.63 9.5 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GAX15858.1 - 0.007 16.7 0.1 5.8 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 GAX15858.1 - 0.0081 16.2 1.0 5.9 6.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAX15858.1 - 0.0091 16.4 1.6 4.2 7.8 0.1 3.8 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 GAX15858.1 - 0.013 15.2 0.1 1.5 8.5 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 GAX15858.1 - 0.019 14.2 0.2 0.25 10.5 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain Ras PF00071.22 GAX15858.1 - 0.024 14.3 0.2 7 6.2 0.0 2.8 2 1 0 2 2 2 0 Ras family AAA_24 PF13479.6 GAX15858.1 - 0.025 14.3 0.0 8.2 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX15858.1 - 0.03 13.7 0.1 9.6 5.5 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 GAX15858.1 - 0.033 14.7 0.0 3.1 8.4 0.0 3.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAX15858.1 - 0.042 14.1 0.0 0.042 14.1 0.0 3.9 4 1 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 GAX15858.1 - 0.054 13.4 0.1 11 5.9 0.0 2.8 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.18 GAX15858.1 - 0.079 12.5 0.1 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B TsaE PF02367.17 GAX15858.1 - 0.25 11.3 3.5 9.1 6.3 0.4 3.4 2 2 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 GAX15858.1 - 0.51 9.5 5.7 5.9 5.9 0.0 3.1 3 1 0 3 3 3 0 G-protein alpha subunit DUF87 PF01935.17 GAX15858.1 - 2.1 8.4 13.4 3.2 7.8 0.0 4.0 5 0 0 5 5 3 0 Helicase HerA, central domain AAA_23 PF13476.6 GAX15858.1 - 2.7 8.5 24.0 0.72 10.3 0.1 5.0 5 0 0 5 5 5 0 AAA domain DUF1744 PF08490.12 GAX15860.1 - 6e-66 222.7 0.0 1.2e-65 221.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 GAX15860.1 - 1.8e-57 195.0 0.0 3.5e-57 194.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 GAX15860.1 - 9.4e-13 47.7 0.1 7.7e-11 41.4 0.1 3.3 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 GAX15860.1 - 5.1e-07 29.6 0.6 2.2e-06 27.5 0.6 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 GAX15860.1 - 3.6e-06 27.1 3.0 5.9e-06 26.4 0.0 3.0 3 0 0 3 3 3 1 RNase_H superfamily PHD PF00628.29 GAX15860.1 - 1.7 8.6 4.4 4.3 7.3 4.4 1.7 1 0 0 1 1 1 0 PHD-finger Topo-VIb_trans PF09239.11 GAX15861.1 - 5.7e-52 175.7 0.0 1.2e-51 174.7 0.0 1.5 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.6 GAX15861.1 - 1.3e-07 31.5 0.3 1.4e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAX15861.1 - 1.1e-06 29.1 0.0 3.7e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GatB_Yqey PF02637.18 GAX15861.1 - 0.14 12.1 0.3 3.8 7.4 0.1 2.5 2 0 0 2 2 2 0 GatB domain zf-MYND PF01753.18 GAX15862.1 - 0.0089 16.1 12.1 0.017 15.2 12.1 1.5 1 0 0 1 1 1 1 MYND finger Guanylate_cyc PF00211.20 GAX15863.1 - 8.8e-45 152.6 0.0 1.6e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.13 GAX15863.1 - 0.015 15.2 0.0 0.058 13.3 0.0 2.0 2 0 0 2 2 2 0 CHASE domain Adaptin_binding PF10199.9 GAX15863.1 - 0.016 15.8 0.6 0.1 13.2 0.7 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Bac_GH3_C PF18034.1 GAX15863.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_16 PF00722.21 GAX15864.1 - 8.1e-30 103.6 0.1 1.1e-29 103.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAX15864.1 - 4.4e-14 51.8 2.1 4.4e-08 32.0 1.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) TPR_8 PF13181.6 GAX15865.1 - 0.00095 19.2 0.0 0.0087 16.2 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX15865.1 - 0.023 14.8 0.0 0.71 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5438 PF17506.2 GAX15865.1 - 0.031 14.6 0.2 0.2 12.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5438) TPR_10 PF13374.6 GAX15865.1 - 0.055 13.3 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15865.1 - 0.064 13.1 0.0 0.75 9.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX15865.1 - 0.073 13.4 0.0 5.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP19 PF11022.8 GAX15866.1 - 0.017 15.5 0.1 0.034 14.5 0.1 1.6 1 1 0 1 1 1 0 ATP synthase subunit K NUDE_C PF04880.13 GAX15866.1 - 1.3 9.5 5.7 5.7 7.4 0.4 2.1 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region SET PF00856.28 GAX15869.1 - 6.3e-13 49.5 0.0 1.6e-06 28.6 0.0 4.3 2 2 0 2 2 2 2 SET domain SAF PF08666.12 GAX15869.1 - 0.001 19.6 0.0 4 8.1 0.0 3.5 3 0 0 3 3 3 2 SAF domain Na_H_Exchanger PF00999.21 GAX15870.1 - 1.2e-68 231.7 28.5 1.5e-68 231.4 28.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.8 GAX15870.1 - 0.5 10.4 2.2 16 5.6 1.7 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 7tm_3 PF00003.22 GAX15871.1 - 5.7e-37 127.7 22.5 7.9e-37 127.2 22.5 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX15871.1 - 3.7e-23 82.4 0.0 6.9e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain Shisa PF13908.6 GAX15871.1 - 0.11 12.7 0.9 20 5.4 0.0 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 GAX15871.1 - 0.12 13.3 1.5 0.46 11.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MRAP PF15183.6 GAX15871.1 - 5.1 7.1 5.6 1 9.3 0.0 2.7 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family GWT1 PF06423.12 GAX15871.1 - 6.6 6.9 12.2 0.39 10.8 1.3 2.7 1 1 0 2 2 2 0 GWT1 TMEM132D_C PF15706.5 GAX15871.1 - 9.6 6.1 5.8 3.7 7.4 2.0 2.2 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term YGGT PF02325.17 GAX15872.1 - 9.6e-12 45.2 4.4 9.6e-12 45.2 4.4 1.6 2 0 0 2 2 2 1 YGGT family SANT_DAMP1_like PF16282.5 GAX15873.1 - 4.2e-25 87.7 0.2 7.6e-25 86.9 0.2 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 ATP_bind_1 PF03029.17 GAX15874.1 - 2.2e-54 184.8 1.1 7.8e-52 176.5 1.1 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein DUF4335 PF14233.6 GAX15874.1 - 0.011 15.7 0.4 0.018 14.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) AAA_22 PF13401.6 GAX15874.1 - 0.011 15.9 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX15874.1 - 0.015 15.8 0.1 0.048 14.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX15874.1 - 0.036 14.4 0.1 0.22 12.0 0.0 2.4 3 0 0 3 3 2 0 RNA helicase AAA_10 PF12846.7 GAX15874.1 - 0.037 12.9 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.6 GAX15874.1 - 0.049 14.1 0.1 0.13 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 GAX15874.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAX15874.1 - 0.098 12.8 0.7 0.2 11.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 GAX15874.1 - 0.11 12.9 0.2 0.37 11.2 0.1 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 GAX15874.1 - 0.15 11.7 0.0 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 GAX15874.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAX15874.1 - 0.15 11.7 0.1 16 5.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Hep_59 PF07052.11 GAX15874.1 - 0.16 12.7 1.9 17 6.3 0.0 2.3 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Cor1 PF04803.12 GAX15875.1 - 0.04 14.1 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region DUF5344 PF17279.2 GAX15875.1 - 0.062 13.9 0.1 0.23 12.1 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5344) DNA_processg_A PF02481.15 GAX15876.1 - 0.00014 21.2 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A AAA_33 PF13671.6 GAX15877.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX15877.1 - 0.00034 21.1 0.2 0.83 10.2 0.3 2.4 1 1 1 2 2 2 2 ABC transporter SMC_N PF02463.19 GAX15877.1 - 0.00075 19.0 2.0 0.089 12.2 0.0 2.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX15877.1 - 0.0025 18.1 0.0 0.0074 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAX15877.1 - 0.0064 15.7 0.0 0.017 14.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 GAX15877.1 - 0.024 15.0 0.0 0.06 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 GAX15877.1 - 0.036 13.9 1.6 2.5 7.8 0.9 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 GAX15877.1 - 0.038 13.6 0.1 0.08 12.5 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAX15877.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 GAX15877.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 GAX15877.1 - 0.13 12.0 0.3 0.4 10.4 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain LapA_dom PF06305.11 GAX15877.1 - 0.19 11.6 3.1 0.55 10.1 0.2 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Wzy_C PF04932.15 GAX15877.1 - 0.77 9.4 5.4 0.35 10.5 0.1 2.5 2 1 0 2 2 2 0 O-Antigen ligase Cyto_heme_lyase PF01265.17 GAX15878.1 - 8.7e-53 179.8 5.0 8.7e-53 179.8 5.0 2.6 2 2 0 2 2 2 1 Cytochrome c/c1 heme lyase DUF3439 PF11921.8 GAX15878.1 - 2.1 8.4 7.9 3.7 7.6 5.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF676 PF05057.14 GAX15879.1 - 1.6e-24 86.7 0.0 1.1e-20 74.1 0.0 2.3 1 1 1 2 2 2 2 Putative serine esterase (DUF676) EutH PF04346.12 GAX15879.1 - 0.2 10.8 0.2 0.3 10.2 0.2 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH LigB PF02900.18 GAX15881.1 - 1.9e-42 145.2 0.0 2.1e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LAGLIDADG_3 PF14528.6 GAX15881.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 LAGLIDADG-like domain Guanylate_cyc PF00211.20 GAX15882.1 - 8.2e-45 152.7 0.0 1.4e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.13 GAX15882.1 - 0.006 16.5 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 CHASE domain Orf78 PF06024.12 GAX15882.1 - 0.75 10.1 6.6 0.19 12.0 0.3 2.8 3 0 0 3 3 3 0 Orf78 (ac78) Vac7 PF12751.7 GAX15882.1 - 1.3 8.4 5.1 16 4.8 2.6 2.2 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 HSBP1 PF06825.12 GAX15883.1 - 0.96 9.4 3.9 13 5.7 0.2 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Phage_holin_3_1 PF05106.12 GAX15884.1 - 0.075 13.5 0.2 0.31 11.5 0.2 2.0 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) SLC35F PF06027.12 GAX15886.1 - 3.6e-42 144.9 15.3 5.6e-39 134.4 10.1 2.0 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 GAX15886.1 - 1.3e-10 40.7 0.7 3.1e-10 39.5 0.7 1.7 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAX15886.1 - 3.5e-10 40.2 24.6 2.1e-05 24.7 5.8 2.9 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 GAX15886.1 - 1.4e-07 31.0 3.7 1.4e-07 31.0 3.7 1.7 2 0 0 2 2 2 1 UAA transporter family Mg_trans_NIPA PF05653.14 GAX15886.1 - 8.6e-05 21.8 0.1 8.6e-05 21.8 0.1 2.3 3 0 0 3 3 3 1 Magnesium transporter NIPA Nuc_sug_transp PF04142.15 GAX15886.1 - 0.0001 21.6 0.2 0.022 14.0 0.1 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter DUF1761 PF08570.10 GAX15886.1 - 0.027 14.7 8.2 0.11 12.7 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1761) DUF4131 PF13567.6 GAX15886.1 - 1.3 8.6 5.0 0.92 9.1 0.1 2.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4131) Nucleotid_trans PF03407.16 GAX15887.1 - 0.0079 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.20 GAX15887.1 - 0.0083 15.7 1.4 0.27 10.8 0.2 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAX15887.1 - 0.16 11.3 0.2 0.25 10.7 0.2 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative SET PF00856.28 GAX15889.1 - 1.5e-07 31.9 0.0 3.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 SET domain Vps52 PF04129.12 GAX15890.1 - 2.5e-86 290.5 7.2 2e-84 284.2 0.3 2.4 3 0 0 3 3 3 2 Vps52 / Sac2 family Sec3_C PF09763.9 GAX15890.1 - 8.2e-11 41.0 13.6 4.4e-09 35.3 12.7 2.8 1 1 0 1 1 1 1 Exocyst complex component Sec3 COG2 PF06148.11 GAX15890.1 - 0.0019 18.3 2.2 0.035 14.2 0.4 3.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 GAX15890.1 - 0.015 14.2 0.6 0.015 14.2 0.6 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein CHDCT2 PF08074.11 GAX15890.1 - 0.019 15.1 1.5 1.2 9.2 0.2 3.5 3 1 0 3 3 3 0 CHDCT2 (NUC038) domain CTK3 PF12243.8 GAX15890.1 - 0.029 14.4 0.6 0.38 10.8 0.1 2.8 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 COG5 PF10392.9 GAX15890.1 - 0.041 14.0 1.1 0.16 12.2 0.3 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 KIX PF02172.16 GAX15890.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 KIX domain HAP1_N PF04849.13 GAX15890.1 - 0.14 11.3 7.5 0.088 12.0 1.5 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 GAX15890.1 - 0.34 11.0 7.3 0.051 13.6 0.7 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) SKA2 PF16740.5 GAX15890.1 - 0.77 9.6 5.7 0.17 11.7 0.2 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Cep57_MT_bd PF06657.13 GAX15890.1 - 3.1 8.3 7.3 1.1 9.7 0.4 3.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 UBN_AB PF14075.6 GAX15890.1 - 3.9 7.2 5.3 1.6 8.4 0.4 2.7 3 0 0 3 3 3 0 Ubinuclein conserved middle domain Peptidase_S10 PF00450.22 GAX15891.1 - 7.7e-86 289.1 0.0 9.8e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase LIP PF03583.14 GAX15891.1 - 0.17 11.2 0.1 0.54 9.5 0.0 1.8 2 0 0 2 2 2 0 Secretory lipase Plasmod_MYXSPDY PF07981.11 GAX15892.1 - 0.096 12.7 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY TPR_12 PF13424.6 GAX15893.1 - 0.00011 22.5 4.6 0.34 11.2 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX15893.1 - 0.0062 16.4 1.5 1.1 9.2 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX15893.1 - 0.03 14.0 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 GAX15893.1 - 0.11 12.6 3.2 2.2 8.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 GAX15894.1 - 4.2e-54 183.7 0.0 5.3e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX15894.1 - 4.7e-22 78.5 0.0 1.2e-21 77.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX15894.1 - 0.0018 17.3 0.0 0.0087 15.0 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAX15894.1 - 0.0023 17.3 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX15894.1 - 0.007 16.3 0.1 0.035 14.0 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Big_3_3 PF13750.6 GAX15894.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Imm7 PF15585.6 GAX15894.1 - 0.036 14.3 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 7 Pkinase_fungal PF17667.1 GAX15894.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PP2C PF00481.21 GAX15895.1 - 1.8e-31 109.7 0.0 2.4e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX15895.1 - 0.00014 21.8 0.0 0.03 14.3 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAX15895.1 - 0.14 11.8 0.1 0.76 9.4 0.1 2.0 1 1 0 1 1 1 0 Protein phosphatase 2C Tyr_Deacylase PF02580.16 GAX15896.1 - 3.3e-47 160.6 0.0 3.8e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase eIF3_subunit PF08597.10 GAX15897.1 - 8.8e-24 84.7 36.0 1.1e-23 84.5 36.0 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit EF-hand_10 PF14788.6 GAX15897.1 - 0.054 13.4 0.4 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 EF hand PALP PF00291.25 GAX15898.1 - 2.5e-60 204.4 0.1 5.8e-60 203.2 0.1 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_26 PF13500.6 GAX15898.1 - 0.1 12.4 0.2 0.75 9.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 GAX15899.1 - 0.0037 15.9 6.1 0.0048 15.5 6.1 1.1 1 0 0 1 1 1 1 Macoilin family Dimer_Tnp_hAT PF05699.14 GAX15901.1 - 9.1e-16 57.4 0.0 1.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MARCKS PF02063.17 GAX15901.1 - 2.8 7.9 11.7 1.5 8.8 2.6 2.8 2 1 1 3 3 3 0 MARCKS family RVT_2 PF07727.14 GAX15903.1 - 6.7e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IstB_IS21 PF01695.17 GAX15903.1 - 0.0082 15.9 0.3 0.022 14.5 0.1 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein TSC21 PF15217.6 GAX15903.1 - 0.18 11.7 1.2 0.72 9.8 0.2 2.1 2 0 0 2 2 2 0 TSC21 family LUD_dom PF02589.15 GAX15904.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 LUD domain FGGY_N PF00370.21 GAX15905.1 - 2.6e-24 86.1 0.0 5.1e-24 85.2 0.0 1.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAX15905.1 - 9.6e-22 77.7 0.2 2e-21 76.6 0.2 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 GAX15905.1 - 0.022 13.0 0.0 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein UIM PF02809.20 GAX15906.1 - 7e-05 22.5 4.7 0.082 12.9 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif MEKHLA PF08670.11 GAX15907.1 - 2.9e-28 98.6 0.0 3.4e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 MEKHLA domain PAS_4 PF08448.10 GAX15907.1 - 0.022 15.0 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 GAX15907.1 - 0.057 13.7 0.0 0.071 13.4 0.0 1.3 1 1 0 1 1 1 0 PAS domain PAS_3 PF08447.12 GAX15907.1 - 0.063 13.6 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 PAS fold Fasciclin PF02469.22 GAX15909.1 - 2.5e-08 34.2 0.0 2.2e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Fasciclin domain DUF285 PF03382.14 GAX15910.1 - 3.4e-18 65.5 1.6 4.2e-18 65.3 1.6 1.1 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 DUF285 PF03382.14 GAX15911.1 - 1e-89 296.5 40.8 7.5e-34 116.1 10.6 3.2 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 HEPN_Swt1 PF18731.1 GAX15911.1 - 0.017 15.5 0.7 3.8 7.9 0.1 2.5 1 1 1 2 2 2 0 Swt1-like HEPN FANCI_S1 PF14675.6 GAX15911.1 - 0.82 9.2 4.5 38 3.8 0.0 4.3 4 1 0 4 4 4 0 FANCI solenoid 1 DUF5050 PF16472.5 GAX15912.1 - 0.00041 19.7 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) ProQ PF04352.13 GAX15912.1 - 0.16 11.9 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 ProQ/FINO family Ldl_recept_b PF00058.17 GAX15912.1 - 0.57 10.7 5.7 1.5 9.4 0.0 4.2 5 1 0 5 5 5 0 Low-density lipoprotein receptor repeat class B DDE_3 PF13358.6 GAX15913.1 - 0.036 13.8 0.4 0.053 13.3 0.4 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease WDCP PF15390.6 GAX15913.1 - 0.054 11.9 0.6 0.064 11.6 0.6 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Activator_LAG-3 PF11498.8 GAX15913.1 - 1.2 8.0 22.6 1.7 7.5 22.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AHSP PF09236.10 GAX15913.1 - 8.3 6.9 11.1 0.19 12.2 1.4 2.6 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein Spt20 PF12090.8 GAX15913.1 - 9.5 5.8 14.1 14 5.2 14.1 1.3 1 0 0 1 1 1 0 Spt20 family Hemerythrin PF01814.23 GAX15914.1 - 0.0011 19.6 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CBFD_NFYB_HMF PF00808.23 GAX15915.1 - 1.6e-10 41.1 0.0 3.9e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX15915.1 - 2.1e-07 31.4 0.0 2.1e-07 31.4 0.0 2.6 2 1 0 2 2 1 1 Core histone H2A/H2B/H3/H4 DUF4746 PF15928.5 GAX15915.1 - 0.0031 17.0 8.8 0.003 17.0 8.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) SDA1 PF05285.12 GAX15915.1 - 0.0089 15.5 22.1 0.011 15.2 22.1 1.2 1 0 0 1 1 1 1 SDA1 Pox_Ag35 PF03286.14 GAX15915.1 - 0.023 14.5 17.8 0.033 14.0 17.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ALMT PF11744.8 GAX15915.1 - 0.035 12.9 4.3 0.041 12.7 4.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RNA_pol_3_Rpc31 PF11705.8 GAX15915.1 - 0.068 13.4 24.3 0.13 12.5 24.3 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Serinc PF03348.15 GAX15915.1 - 0.096 11.6 0.3 0.11 11.4 0.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NOA36 PF06524.12 GAX15915.1 - 0.11 11.8 21.2 0.15 11.4 21.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 GAX15915.1 - 0.11 11.5 7.6 0.14 11.1 7.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 GAX15915.1 - 0.12 10.5 29.7 0.14 10.3 29.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RR_TM4-6 PF06459.12 GAX15915.1 - 0.14 12.0 11.5 0.18 11.6 11.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 GAX15915.1 - 0.16 12.3 14.5 0.22 11.8 14.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 GAX15915.1 - 0.19 9.9 28.0 0.23 9.6 28.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GAX15915.1 - 0.3 10.2 25.3 0.44 9.6 25.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Slu7 PF11708.8 GAX15915.1 - 0.33 10.7 19.1 0.46 10.2 19.1 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor SID-1_RNA_chan PF13965.6 GAX15915.1 - 0.37 9.2 0.9 0.42 9.0 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BUD22 PF09073.10 GAX15915.1 - 0.37 10.1 26.2 0.43 9.9 26.2 1.1 1 0 0 1 1 1 0 BUD22 Gti1_Pac2 PF09729.9 GAX15915.1 - 0.42 10.7 7.7 1.7 8.7 8.6 1.5 2 0 0 2 2 1 0 Gti1/Pac2 family DUF5427 PF10310.9 GAX15915.1 - 0.53 9.2 16.4 0.71 8.8 16.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDC45 PF02724.14 GAX15915.1 - 0.59 8.4 21.7 0.66 8.2 21.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 GAX15915.1 - 0.92 8.8 22.0 1.4 8.3 22.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleo_P87 PF07267.11 GAX15915.1 - 1.1 8.0 11.8 1.4 7.7 11.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC27 PF09507.10 GAX15915.1 - 1.4 8.3 23.1 1.8 7.8 23.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIF_alpha PF05793.12 GAX15915.1 - 1.7 7.1 29.5 2.2 6.8 29.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAP_alpha PF03896.16 GAX15915.1 - 2.3 7.4 13.7 3 7.0 13.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 GAX15915.1 - 2.5 8.0 17.3 4.1 7.3 17.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2722 PF10846.8 GAX15915.1 - 4.2 6.2 13.5 5.3 5.9 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FAM60A PF15396.6 GAX15915.1 - 5.1 7.0 7.5 6.7 6.7 7.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.8 GAX15915.1 - 5.4 5.7 13.9 7.7 5.2 13.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SURF2 PF05477.11 GAX15915.1 - 6.8 6.3 15.6 10 5.7 15.6 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Presenilin PF01080.17 GAX15915.1 - 6.9 5.3 10.4 8.8 5.0 10.4 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 GAX15915.1 - 7.5 5.0 11.6 8.4 4.9 11.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Afi1 PF07792.12 GAX15915.1 - 7.6 7.0 20.4 11 6.6 20.1 1.5 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking LAP1C PF05609.12 GAX15915.1 - 9.3 5.2 16.9 11 5.0 16.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) 60KD_IMP PF02096.20 GAX15917.1 - 6.8e-53 179.0 0.7 9.6e-53 178.5 0.7 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2062 PF09835.9 GAX15917.1 - 0.041 13.8 3.9 0.2 11.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) LAP1C PF05609.12 GAX15917.1 - 1.7 7.6 8.2 0.31 10.1 0.1 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) 7tm_3 PF00003.22 GAX15918.1 - 9.2e-16 58.3 9.2 9.2e-16 58.3 9.2 1.8 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4834 PF16118.5 GAX15918.1 - 0.0024 18.8 0.2 3.8 8.6 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) Shisa PF13908.6 GAX15918.1 - 0.0025 18.1 2.3 0.0025 18.1 2.3 3.0 3 0 0 3 3 3 2 Wnt and FGF inhibitory regulator Mucin PF01456.17 GAX15918.1 - 1.8 8.6 22.0 0.1 12.6 4.7 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein Cadherin_C_2 PF16492.5 GAX15918.1 - 3.3 8.5 6.0 0.92 10.3 1.0 2.8 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal DUF285 PF03382.14 GAX15919.1 - 2.2e-18 66.2 3.4 2.6e-18 65.9 3.4 1.1 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 DUF285 PF03382.14 GAX15920.1 - 7.2e-20 71.0 0.5 8.9e-20 70.7 0.5 1.0 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 TGase_elicitor PF16683.5 GAX15920.1 - 0.0063 15.3 0.1 0.0073 15.1 0.1 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor Sigma70_r3 PF04539.16 GAX15922.1 - 3.8e-13 49.3 7.1 3.4e-05 23.9 1.4 3.7 3 0 0 3 3 3 3 Sigma-70 region 3 Sigma70_r2 PF04542.14 GAX15922.1 - 6.7e-13 48.2 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 GAX15922.1 - 0.0039 16.8 0.1 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 GAX15922.1 - 0.0094 15.5 0.1 0.054 13.0 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 NUDIX PF00293.28 GAX15922.1 - 0.054 13.6 0.6 0.17 11.9 0.6 2.0 1 1 0 1 1 1 0 NUDIX domain HTH_29 PF13551.6 GAX15922.1 - 0.087 12.9 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Fer4_19 PF06902.11 GAX15923.1 - 0.076 13.1 0.1 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster MMR_HSR1 PF01926.23 GAX15924.1 - 3.8e-18 65.6 0.4 1.1e-17 64.2 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX15924.1 - 1.7e-08 34.2 0.1 5e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX15924.1 - 4.5e-06 26.8 3.4 0.025 14.6 0.4 2.9 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 GAX15924.1 - 1.8e-05 24.4 0.3 0.00084 18.9 0.1 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 GAX15924.1 - 6.3e-05 22.5 0.2 0.00021 20.8 0.1 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAX15924.1 - 0.00021 21.3 1.0 0.015 15.2 0.0 2.7 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 GAX15924.1 - 0.00091 18.7 0.9 0.0017 17.8 0.3 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit KH_2 PF07650.17 GAX15924.1 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 KH domain AIG1 PF04548.16 GAX15924.1 - 0.011 15.1 0.2 0.019 14.3 0.2 1.4 1 0 0 1 1 1 0 AIG1 family MCM PF00493.23 GAX15924.1 - 0.027 13.6 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain LysR_substrate PF03466.20 GAX15924.1 - 0.039 13.3 0.1 0.095 12.1 0.1 1.6 1 0 0 1 1 1 0 LysR substrate binding domain SRP54 PF00448.22 GAX15924.1 - 0.098 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrbM PF07424.11 GAX15924.1 - 0.12 12.3 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 TrbM Med7 PF05983.11 GAX15925.1 - 1.5 8.9 8.9 77 3.3 8.9 2.5 1 1 0 1 1 1 0 MED7 protein ATPase_gene1 PF09527.10 GAX15926.1 - 0.48 10.6 5.6 1 9.6 5.6 1.6 1 1 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter GYF PF02213.16 GAX15927.1 - 4.4e-10 39.1 0.1 1.3e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 GYF domain ShK PF01549.24 GAX15928.1 - 2.2e-09 37.7 8.2 2.2e-09 37.7 8.2 2.5 3 0 0 3 3 3 1 ShK domain-like Methyltransf_25 PF13649.6 GAX15928.1 - 0.022 15.4 0.2 0.38 11.5 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAX15928.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GAS PF13851.6 GAX15928.1 - 0.2 11.0 0.2 0.59 9.4 0.0 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Choline_kinase PF01633.20 GAX15931.1 - 1.6e-13 50.8 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAX15931.1 - 1.1e-10 41.8 0.0 2.3e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2576 PF10845.8 GAX15931.1 - 0.06 13.0 0.4 7.7 6.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) DUF4961 PF16328.5 GAX15934.1 - 0.023 14.0 0.0 0.028 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) Pyr_redox_2 PF07992.14 GAX15935.1 - 7.3e-61 206.0 2.5 1.3e-60 205.2 2.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX15935.1 - 5.4e-30 103.9 0.6 1.5e-29 102.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX15935.1 - 1.3e-18 67.3 8.7 3.1e-18 66.1 0.7 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX15935.1 - 5.4e-14 52.2 3.3 4.2e-12 45.9 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX15935.1 - 7.5e-06 25.3 5.0 7.6e-06 25.3 0.1 2.6 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAX15935.1 - 5.1e-05 22.8 0.4 9.7e-05 21.9 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX15935.1 - 0.00049 18.9 2.2 0.24 10.0 0.9 2.7 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 GAX15935.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 GAX15935.1 - 0.021 15.2 0.6 4.4 7.8 0.1 2.8 3 1 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAX15935.1 - 0.045 12.8 0.5 0.44 9.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 GAX15935.1 - 0.057 13.3 0.3 0.057 13.3 0.3 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAX15935.1 - 0.087 12.1 4.5 1.3 8.3 0.6 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX15935.1 - 0.12 12.0 6.3 0.65 9.5 0.2 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX15935.1 - 0.48 9.4 8.3 0.31 10.1 3.2 2.8 3 1 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 GAX15935.1 - 7.8 6.8 7.8 0.32 11.3 1.3 2.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX15936.1 - 5.7e-28 98.0 0.2 3.5e-27 95.4 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GAX15936.1 - 1.9e-22 79.2 0.2 3.1e-22 78.5 0.2 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 GAX15936.1 - 2.8e-11 43.8 0.1 2.5e-07 31.2 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX15936.1 - 3.6e-09 36.7 0.0 1e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAX15936.1 - 1.3e-08 34.5 0.3 0.0034 16.7 0.1 3.7 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAX15936.1 - 4.6e-07 29.5 0.0 7.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAX15936.1 - 2.5e-06 26.5 0.2 4.6e-05 22.3 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAX15936.1 - 3.5e-06 26.6 0.0 3.5e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAX15936.1 - 5.5e-06 25.8 0.1 0.00066 19.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 GAX15936.1 - 0.0005 19.3 0.2 0.0072 15.5 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 GAX15936.1 - 0.00051 19.5 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 GAX15936.1 - 0.00077 18.7 0.0 0.00077 18.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAX15936.1 - 0.001 18.4 0.0 0.064 12.5 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX15936.1 - 0.0013 18.4 6.5 0.0034 17.0 0.1 3.0 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAX15936.1 - 0.0016 17.8 0.1 0.0016 17.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GAX15936.1 - 0.0035 17.3 0.1 0.23 11.4 0.1 3.0 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 GAX15936.1 - 0.0067 16.9 0.3 0.81 10.2 0.0 2.7 3 0 0 3 3 2 1 Putative NAD(P)-binding FMO-like PF00743.19 GAX15936.1 - 0.009 14.5 0.0 0.11 10.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like YjeF_N PF03853.15 GAX15936.1 - 0.0091 15.9 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.23 GAX15936.1 - 0.033 14.2 0.0 0.079 12.9 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K_oxygenase PF13434.6 GAX15936.1 - 0.033 13.3 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AdoHcyase_NAD PF00670.21 GAX15936.1 - 0.038 14.1 0.1 9.4 6.3 0.0 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DNA_pol_A_exo1 PF01612.20 GAX15937.1 - 3.7e-18 65.8 0.0 6.4e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 GAX15937.1 - 1.6e-05 24.8 0.4 4e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 HRDC domain R3H PF01424.22 GAX15937.1 - 0.11 12.5 0.0 0.43 10.6 0.0 2.0 1 0 0 1 1 1 0 R3H domain Aa_trans PF01490.18 GAX15938.1 - 8.4e-37 126.8 18.7 1.1e-21 77.1 1.8 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DnaJ PF00226.31 GAX15939.1 - 1.4e-17 63.5 2.0 1.4e-17 63.5 2.0 2.0 2 0 0 2 2 2 1 DnaJ domain Phage-MuB_C PF09077.11 GAX15939.1 - 0.0058 16.5 0.3 5.2 7.0 0.0 3.4 3 1 0 3 3 3 1 Mu B transposition protein, C terminal SH3BP5 PF05276.14 GAX15939.1 - 0.024 14.4 2.7 0.037 13.8 2.7 1.3 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF913 PF06025.12 GAX15939.1 - 1 8.2 4.2 1.6 7.6 4.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Rotamase PF00639.21 GAX15939.1 - 1.4 9.9 4.6 6 7.9 0.2 3.0 2 1 1 3 3 3 0 PPIC-type PPIASE domain DUF4407 PF14362.6 GAX15939.1 - 3.3 7.0 5.6 4 6.7 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3246 PF11596.8 GAX15939.1 - 7.9 5.8 8.5 0.24 10.8 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) V-set_CD47 PF08204.11 GAX15940.1 - 0.034 14.1 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain HicB PF05534.12 GAX15940.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 HicB family E6 PF00518.17 GAX15941.1 - 0.079 13.4 0.9 0.2 12.1 0.9 1.7 1 0 0 1 1 1 0 Early Protein (E6) FMO-like PF00743.19 GAX15942.1 - 1.3e-38 132.7 0.0 4.3e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAX15942.1 - 2.9e-19 69.4 0.0 4e-09 36.2 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX15942.1 - 1.7e-07 31.4 0.3 7.4e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX15942.1 - 3.1e-07 29.9 0.0 5.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX15942.1 - 3.9e-07 30.0 0.0 3.6e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAX15942.1 - 4e-07 29.5 0.3 6.3e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAX15942.1 - 4.3e-07 30.0 0.0 1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAX15942.1 - 4.3e-06 26.1 0.5 6.5e-06 25.6 0.1 1.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAX15942.1 - 0.0059 15.7 1.3 0.015 14.4 0.6 1.9 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAX15942.1 - 0.007 15.1 0.3 0.012 14.4 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein MCRA PF06100.11 GAX15942.1 - 0.013 14.3 0.0 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 MCRA family Lycopene_cycl PF05834.12 GAX15942.1 - 0.023 13.7 0.0 0.066 12.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 GAX15942.1 - 0.025 13.5 0.3 0.048 12.5 0.3 1.5 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 GAX15942.1 - 0.11 11.8 0.8 0.15 11.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 GAX15942.1 - 0.18 11.1 0.8 0.29 10.5 0.8 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase PAS_7 PF12860.7 GAX15943.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 PAS fold Glycos_transf_2 PF00535.26 GAX15944.1 - 1.8e-20 73.4 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX15944.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 DUF4605 PF15378.6 GAX15944.1 - 0.18 11.7 2.7 0.44 10.4 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) DnaJ PF00226.31 GAX15945.1 - 3.4e-13 49.5 0.1 5.6e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Arm PF00514.23 GAX15946.1 - 5.4e-05 23.1 7.4 0.0041 17.1 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAX15946.1 - 0.00031 21.2 7.8 0.01 16.3 0.0 5.1 4 1 1 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 GAX15946.1 - 0.00087 19.6 3.8 0.0064 16.9 0.2 3.4 3 1 1 4 4 4 1 HEAT repeats DUF383 PF04063.14 GAX15946.1 - 0.0064 16.2 0.3 0.049 13.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF383) HEAT PF02985.22 GAX15946.1 - 0.15 12.4 7.2 0.25 11.7 0.0 4.6 6 0 0 6 6 6 0 HEAT repeat Bromodomain PF00439.25 GAX15949.1 - 2.6e-07 30.6 0.0 6.9e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 GAX15949.1 - 8.1e-05 22.4 0.5 0.00018 21.3 0.5 1.6 1 0 0 1 1 1 1 PHD-finger FYRN PF05964.14 GAX15949.1 - 0.00098 18.9 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Tudor-knot PF11717.8 GAX15949.1 - 0.016 15.1 0.1 0.054 13.4 0.1 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain PriA_3primeBD PF17764.1 GAX15949.1 - 0.11 12.4 0.0 0.41 10.6 0.0 1.9 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) PRP1_N PF06424.12 GAX15950.1 - 3.9e-32 111.7 32.6 7e-22 78.4 5.6 5.0 4 1 1 5 5 5 3 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 GAX15950.1 - 1.7e-23 81.3 32.9 0.0093 16.7 0.5 13.0 7 4 6 13 13 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 GAX15950.1 - 8.9e-16 58.2 12.9 7.9e-06 26.3 0.1 8.8 8 1 2 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX15950.1 - 5.1e-07 29.3 18.4 1.3 9.3 0.0 9.1 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX15950.1 - 9.5e-06 26.2 18.6 0.14 12.8 1.3 7.1 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX15950.1 - 0.0002 21.3 0.9 63 4.2 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX15950.1 - 0.00069 19.3 0.2 4.8 7.2 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX15950.1 - 0.0014 18.8 0.3 4.4 7.6 0.1 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 GAX15950.1 - 0.0025 17.9 4.1 3 7.8 0.1 4.2 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_11 PF13414.6 GAX15950.1 - 0.01 15.5 1.1 2.7 7.8 0.0 4.2 4 0 0 4 4 4 0 TPR repeat DUF3808 PF10300.9 GAX15950.1 - 0.011 14.6 3.5 1.4 7.6 0.0 4.2 3 2 2 5 5 5 0 Protein of unknown function (DUF3808) DUF4148 PF13663.6 GAX15950.1 - 0.044 14.0 1.8 0.092 12.9 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) TPR_17 PF13431.6 GAX15950.1 - 0.058 13.8 6.1 13 6.5 0.0 7.1 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX15950.1 - 0.44 11.3 9.6 1.4e+02 3.4 0.2 7.3 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX15950.1 - 2.2 8.6 11.4 9.1 6.6 0.6 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat EXS PF03124.14 GAX15951.1 - 2.6e-67 227.5 8.2 3e-67 227.3 8.2 1.1 1 0 0 1 1 1 1 EXS family Sec1 PF00995.23 GAX15954.1 - 6.3e-88 296.4 0.0 7.9e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Lipase_3 PF01764.25 GAX15956.1 - 4.2e-08 33.2 0.0 8.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 GAX15956.1 - 0.036 13.8 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Trypan_PARP PF05887.11 GAX15957.1 - 0.002 18.1 42.0 0.002 18.1 42.0 3.5 1 1 2 3 3 3 1 Procyclic acidic repetitive protein (PARP) UDPGP PF01704.18 GAX15958.1 - 4.9e-18 65.0 0.0 2e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FAM60A PF15396.6 GAX15960.1 - 0.033 14.2 5.6 0.058 13.4 5.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Nse5 PF08691.10 GAX15960.1 - 0.41 9.3 2.8 0.67 8.6 2.8 1.3 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 RPE65 PF03055.15 GAX15962.1 - 2.6e-71 241.2 0.0 3.1e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein UDG PF03167.19 GAX15963.1 - 8.5e-21 74.6 0.0 1.6e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Fapy_DNA_glyco PF01149.24 GAX15963.1 - 2.4e-13 50.7 0.0 6.8e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 GAX15963.1 - 1.3e-11 44.3 0.0 2.4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 GAX15963.1 - 0.099 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) LuxT_C PF18285.1 GAX15963.1 - 0.1 13.2 1.2 52 4.5 0.0 4.0 4 1 1 5 5 5 0 Tetracycline repressor LuxT C-terminal domain LSM14 PF12701.7 GAX15964.1 - 1.4e-27 95.5 0.0 2.5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 GAX15964.1 - 1.5e-06 29.0 13.9 3.1e-05 24.8 0.4 3.1 2 2 1 3 3 3 2 FDF domain SM-ATX PF14438.6 GAX15964.1 - 2.6e-05 24.3 0.0 5.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.11 GAX15964.1 - 1.7 9.4 22.7 1.4 9.7 18.9 2.2 2 0 0 2 2 2 0 Glycine rich protein family HAD_2 PF13419.6 GAX15965.1 - 1.2e-27 97.1 0.0 1.9e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX15965.1 - 1.1e-14 55.3 0.9 3.4e-13 50.4 0.9 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX15965.1 - 3.3e-10 39.9 0.0 5.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GAX15965.1 - 0.00031 21.2 0.1 0.0011 19.4 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAX15965.1 - 0.017 15.2 0.0 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.21 GAX15966.1 - 1.7e-46 158.4 0.0 3.8e-46 157.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-Nse PF11789.8 GAX15966.1 - 0.071 12.9 0.1 0.25 11.2 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 GAX15966.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Myb_DNA-binding PF00249.31 GAX15967.1 - 7.1e-10 38.9 0.1 7.1e-10 38.9 0.1 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.17 GAX15967.1 - 3.8e-08 33.0 2.5 7e-08 32.2 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 GAX15967.1 - 3e-06 27.4 0.0 1.1e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 GAX15967.1 - 0.014 15.7 3.6 0.037 14.3 3.6 1.7 1 0 0 1 1 1 0 C1 domain IBR PF01485.21 GAX15968.1 - 2.3e-11 43.8 22.2 2.4e-07 30.9 3.8 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain GPDPase_memb PF10110.9 GAX15969.1 - 9.4e-05 21.3 14.1 9.4e-05 21.3 14.1 2.2 2 0 0 2 2 2 2 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF1689 PF07954.11 GAX15970.1 - 2.7 8.4 4.6 4.1 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) GPDPase_memb PF10110.9 GAX15971.1 - 6.5 5.4 31.6 1.4 7.6 25.6 2.5 2 1 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase TRAM_LAG1_CLN8 PF03798.16 GAX15973.1 - 6e-09 35.9 18.1 7e-09 35.7 17.5 1.4 1 1 0 1 1 1 1 TLC domain AGTRAP PF06396.11 GAX15973.1 - 0.014 15.2 0.4 0.026 14.3 0.4 1.4 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF21 PF01595.20 GAX15973.1 - 0.13 12.0 1.2 0.24 11.1 1.2 1.5 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain ATP-synt_I PF03899.15 GAX15973.1 - 4.5 7.7 9.5 0.24 11.8 1.9 2.7 2 1 1 3 3 3 0 ATP synthase I chain DUF4234 PF14018.6 GAX15973.1 - 5 7.3 6.6 16 5.7 5.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) 2TM PF13239.6 GAX15973.1 - 5 7.5 8.5 1.6 9.1 5.4 1.8 2 0 0 2 2 2 0 2TM domain Smg4_UPF3 PF03467.15 GAX15974.1 - 0.00055 20.0 0.2 0.00055 20.0 0.2 2.4 3 0 0 3 3 3 1 Smg-4/UPF3 family Rab5ip PF07019.12 GAX15975.1 - 0.25 12.0 0.0 0.25 12.0 0.0 3.5 2 1 1 3 3 3 0 Rab5-interacting protein (Rab5ip) GPDPase_memb PF10110.9 GAX15976.1 - 0.00013 20.9 26.1 0.092 11.5 26.0 2.9 1 1 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase GATase_4 PF13230.6 GAX15978.1 - 2e-83 279.5 0.0 2.8e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAX15978.1 - 0.00039 20.6 0.0 0.00067 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Helicase_C PF00271.31 GAX15979.1 - 2.7e-24 85.7 0.3 8.8e-24 84.0 0.3 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX15979.1 - 4.3e-21 75.5 0.0 1.3e-20 73.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAX15979.1 - 2e-05 24.0 0.7 3.4e-05 23.2 0.2 1.5 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAX15979.1 - 8.6e-05 22.6 0.1 0.00054 20.0 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit TPR_1 PF00515.28 GAX15980.1 - 9.7e-06 25.2 3.9 4.2e-05 23.2 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX15980.1 - 9.5e-05 22.2 5.2 0.00025 20.9 1.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX15980.1 - 0.00011 21.8 3.7 0.005 16.5 1.1 2.6 1 1 1 2 2 2 2 TPR repeat TPR_19 PF14559.6 GAX15980.1 - 0.00033 21.1 5.4 0.00033 21.1 5.4 2.2 3 0 0 3 3 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX15980.1 - 0.00063 19.8 0.5 0.021 15.0 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX15980.1 - 0.00063 20.3 4.9 0.0013 19.4 3.3 2.6 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX15980.1 - 0.00082 19.5 0.7 0.00082 19.5 0.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX15980.1 - 0.00091 19.3 0.5 0.0026 17.8 0.5 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 GAX15980.1 - 0.0027 17.6 0.2 0.0027 17.6 0.2 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX15980.1 - 0.03 14.7 3.1 0.05 14.0 0.6 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Peptidase_S46 PF10459.9 GAX15980.1 - 0.043 12.5 1.8 0.039 12.6 0.4 1.5 1 1 1 2 2 2 0 Peptidase S46 TPR_6 PF13174.6 GAX15980.1 - 0.13 13.0 2.7 0.96 10.2 2.7 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX15980.1 - 0.2 11.9 1.3 0.39 11.0 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FAD_binding_3 PF01494.19 GAX15981.1 - 5.5e-17 62.0 0.6 2.8e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 GAX15981.1 - 8.4e-05 21.8 3.2 0.00022 20.4 3.2 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAX15981.1 - 0.00017 21.8 1.5 0.00047 20.3 0.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX15981.1 - 0.00032 20.0 0.4 0.0016 17.7 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX15981.1 - 0.0014 18.0 0.4 0.0026 17.1 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAX15981.1 - 0.0017 17.1 1.3 0.0026 16.5 1.3 1.3 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 GAX15981.1 - 0.0027 16.8 0.0 0.41 9.7 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.27 GAX15981.1 - 0.0029 18.1 0.1 0.0059 17.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX15981.1 - 0.017 14.7 1.5 0.017 14.7 1.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 GAX15981.1 - 0.057 12.5 1.1 0.086 11.9 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAX15981.1 - 0.15 10.9 0.5 0.93 8.3 0.7 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 GAX15981.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GAX15981.1 - 0.46 9.8 3.7 0.7 9.2 3.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase VDE PF07137.11 GAX15982.1 - 2.4e-80 269.5 2.0 3e-80 269.2 2.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Lipocalin PF00061.23 GAX15982.1 - 1.2e-05 25.5 0.1 2e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 GAX15982.1 - 0.0042 17.0 0.1 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Lipocalin-like domain Acetyltransf_13 PF13880.6 GAX15982.1 - 0.092 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FPN1 PF06963.12 GAX15983.1 - 7.1e-83 278.6 12.5 9.5e-83 278.2 12.5 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) PPTA PF01239.22 GAX15984.1 - 8.9e-32 107.9 15.1 1.5e-09 37.2 0.4 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat WW PF00397.26 GAX15986.1 - 2.3e-06 27.6 0.0 5.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 WW domain zf-U1 PF06220.12 GAX15986.1 - 2.6e-06 27.1 0.1 3.8e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 U1 zinc finger HlyIII PF03006.20 GAX15987.1 - 2.3e-33 115.8 17.2 3.6e-33 115.2 17.2 1.2 1 0 0 1 1 1 1 Haemolysin-III related LRR_6 PF13516.6 GAX15987.1 - 4.2e-06 26.4 0.0 1.1 9.5 0.0 3.9 3 0 0 3 3 3 3 Leucine Rich repeat zf-TAZ PF02135.16 GAX15988.1 - 1.5e-34 118.3 67.1 7.1e-16 58.4 16.0 5.4 6 0 0 6 6 6 3 TAZ zinc finger HAT_KAT11 PF08214.11 GAX15988.1 - 2.7e-31 109.1 0.0 5.2e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 GAX15988.1 - 3.4e-19 68.7 0.0 1.1e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Bromodomain ZZ PF00569.17 GAX15988.1 - 2.3e-07 30.5 6.4 2.3e-07 30.5 6.4 4.3 5 1 0 5 5 5 1 Zinc finger, ZZ type PHD PF00628.29 GAX15988.1 - 4.9e-07 29.5 7.8 4.9e-07 29.5 7.8 3.8 4 0 0 4 4 4 1 PHD-finger KIX_2 PF16987.5 GAX15988.1 - 9.9e-05 22.3 1.9 0.00031 20.7 0.0 2.7 2 0 0 2 2 2 1 KIX domain N2227 PF07942.12 GAX15989.1 - 3.2e-48 164.3 0.0 5e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 GAX15989.1 - 0.00019 21.3 0.0 0.0055 16.6 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX15989.1 - 0.00068 20.3 0.0 0.0045 17.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX15989.1 - 0.0031 18.1 0.0 0.14 12.8 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX15989.1 - 0.023 14.5 0.1 0.81 9.5 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAX15989.1 - 0.058 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Mito_carr PF00153.27 GAX15990.1 - 1.1e-52 175.9 2.8 9.8e-18 63.9 0.0 3.1 1 1 2 3 3 3 3 Mitochondrial carrier protein Lipase_3 PF01764.25 GAX15991.1 - 1.9e-05 24.6 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) H2O2_YaaD PF03883.14 GAX15991.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Peroxide stress protein YaaA DUF2974 PF11187.8 GAX15991.1 - 0.24 10.9 0.6 0.69 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF1499 PF07386.11 GAX15992.1 - 3e-13 50.3 0.1 3.9e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) EF-hand_5 PF13202.6 GAX15993.1 - 0.038 13.5 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 GAX15993.1 - 0.079 13.4 0.1 0.29 11.6 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 GAX15993.1 - 0.087 12.7 0.1 0.61 10.0 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 GAX15993.1 - 0.11 12.1 0.0 0.42 10.3 0.0 2.0 1 0 0 1 1 1 0 EF hand Sulfate_transp PF00916.20 GAX15994.1 - 2.6e-36 125.2 5.7 5.2e-36 124.2 5.7 1.5 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 GAX15994.1 - 3e-09 36.8 0.0 6.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 GAX15994.1 - 1.8e-08 34.0 0.3 4e-08 32.9 0.3 1.5 1 0 0 1 1 1 1 STAS domain L_protein_N PF15518.6 GAX15994.1 - 0.068 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 L protein N-terminus Pkinase PF00069.25 GAX15995.1 - 3.7e-21 75.7 0.0 2.2e-20 73.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 GAX15995.1 - 1e-19 71.2 0.0 6.1e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX15995.1 - 7.1e-07 29.3 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAX15995.1 - 5.9e-06 26.1 0.0 2.1e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PDZ_6 PF17820.1 GAX15995.1 - 4.9e-05 23.1 0.0 0.00013 21.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 GAX15995.1 - 9.7e-05 21.8 0.0 0.00034 20.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX15995.1 - 0.0012 18.8 0.5 0.003 17.5 0.5 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX15995.1 - 0.051 12.4 0.0 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Ribosomal_L34e PF01199.18 GAX15996.1 - 1.1e-33 115.4 5.6 1.3e-33 115.1 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Ribosomal_L36e PF01158.18 GAX15997.1 - 3.5e-22 78.5 0.8 3.9e-22 78.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 2-oxoacid_dh PF00198.23 GAX15998.1 - 6e-62 209.1 1.2 6.4e-62 209.0 0.1 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX15998.1 - 1.5e-18 66.4 0.1 4.8e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 GAX15998.1 - 2.3e-12 47.0 0.1 4.1e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAX15998.1 - 0.0095 15.7 1.3 0.6 10.0 0.0 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_D23 PF16576.5 GAX15998.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion MtrB PF05440.12 GAX15998.1 - 0.16 12.4 0.1 0.67 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B PAP_fibrillin PF04755.12 GAX15999.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 PAP_fibrillin DMAP1 PF05499.12 GAX15999.1 - 0.19 11.6 0.1 0.3 11.0 0.1 1.2 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) CDC50 PF03381.15 GAX16000.1 - 0.078 12.5 0.6 0.14 11.7 0.6 1.3 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Pirin PF02678.16 GAX16001.1 - 0.057 13.4 0.4 0.1 12.6 0.1 1.6 2 0 0 2 2 2 0 Pirin MFS_1 PF07690.16 GAX16002.1 - 2.9e-31 108.7 53.2 5.8e-26 91.2 28.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 GAX16004.1 - 1.1e-13 51.1 0.4 2.5e-13 50.0 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX16004.1 - 4.6e-05 23.6 0.5 0.00016 21.8 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX16004.1 - 0.00039 20.2 2.0 0.00043 20.1 0.1 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Flocculin_t3 PF13928.6 GAX16005.1 - 0.036 14.6 0.0 0.085 13.4 0.0 1.6 1 0 0 1 1 1 0 Flocculin type 3 repeat CP12 PF02672.15 GAX16006.1 - 2e-07 31.6 12.8 0.00031 21.4 0.4 3.5 1 1 3 4 4 4 2 CP12 domain SOAR PF16533.5 GAX16006.1 - 0.025 14.5 1.4 0.87 9.6 0.0 2.6 2 1 1 3 3 3 0 STIM1 Orai1-activating region Phage_ABA_S PF18066.1 GAX16006.1 - 0.072 13.8 2.1 0.3 11.8 0.4 2.3 2 1 0 2 2 2 0 Phage ABA sandwich domain DUF2188 PF09954.9 GAX16006.1 - 4 7.7 5.3 48 4.2 1.2 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Ribosomal_S3_C PF00189.20 GAX16007.1 - 1.1e-19 70.7 3.0 3.4e-19 69.1 3.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAX16007.1 - 1.6e-09 37.5 0.0 3.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 KH domain nec1 PF10379.9 GAX16007.1 - 0.16 11.4 0.1 2.5 7.5 0.1 2.1 1 1 1 2 2 2 0 Virulence protein nec1 Chloroa_b-bind PF00504.21 GAX16008.1 - 1e-39 136.6 0.6 1.4e-39 136.2 0.6 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Adenylsucc_synt PF00709.21 GAX16009.1 - 3.9e-168 559.7 0.0 4.5e-168 559.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase G6PD_N PF00479.22 GAX16009.1 - 0.17 12.5 0.0 0.28 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Rav1p_C PF12234.8 GAX16010.1 - 1e-33 116.7 0.4 1.7e-33 116.0 0.4 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal SH2 PF00017.24 GAX16010.1 - 8.4e-05 22.6 0.0 0.0015 18.6 0.0 2.6 2 0 0 2 2 2 1 SH2 domain PDZ PF00595.24 GAX16010.1 - 0.00076 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX16010.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Organ_specific PF10950.8 GAX16010.1 - 0.08 13.7 2.0 16 6.2 0.2 3.1 1 1 2 3 3 3 0 Organ specific protein PT PF04886.12 GAX16011.1 - 0.036 13.6 0.8 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 PT repeat TALPID3 PF15324.6 GAX16011.1 - 0.71 7.5 15.3 0.89 7.1 15.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Myosin_head PF00063.21 GAX16012.1 - 2.3e-211 703.6 1.6 3.1e-211 703.2 1.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 GAX16012.1 - 0.00011 22.5 0.0 0.00042 20.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 GAX16012.1 - 0.0018 17.3 0.2 0.0038 16.2 0.2 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.6 GAX16012.1 - 0.0024 18.3 0.1 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 GAX16012.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 GAX16012.1 - 0.092 11.8 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 GAX16012.1 - 0.097 13.0 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_lid_6 PF17866.1 GAX16012.1 - 0.12 12.6 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA lid domain TsaE PF02367.17 GAX16012.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAX16012.1 - 0.14 12.6 0.1 0.71 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 GAX16012.1 - 1.4 9.4 3.4 3.3 8.2 0.3 2.7 2 1 0 2 2 2 0 ABC transporter Rhomboid PF01694.22 GAX16013.1 - 2.6e-21 76.2 15.5 3.8e-21 75.7 15.5 1.2 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 GAX16013.1 - 0.00059 19.8 13.5 0.0013 18.6 13.5 1.5 1 1 0 1 1 1 1 Der1-like family SNAPc_SNAP43 PF09808.9 GAX16013.1 - 0.29 11.0 0.8 0.44 10.4 0.8 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF1751 PF08551.10 GAX16013.1 - 0.37 11.4 7.9 0.048 14.2 3.7 1.7 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Prp19 PF08606.11 GAX16014.1 - 1.7e-25 88.8 2.7 4.9e-25 87.3 2.7 1.8 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 GAX16014.1 - 4.4e-07 30.5 4.3 0.057 14.3 0.1 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX16014.1 - 9.3e-07 29.1 5.8 0.036 14.3 0.1 5.5 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX16014.1 - 2.3e-05 23.9 0.1 6.5e-05 22.4 0.1 1.7 2 1 0 2 2 2 1 WD40-like domain U-box PF04564.15 GAX16014.1 - 0.00014 21.9 0.0 0.00062 19.9 0.0 2.0 2 0 0 2 2 2 1 U-box domain Coatomer_WDAD PF04053.14 GAX16014.1 - 0.00038 19.6 0.4 0.14 11.1 0.1 2.4 2 1 0 2 2 2 2 Coatomer WD associated region Frtz PF11768.8 GAX16014.1 - 0.0033 15.8 0.2 0.046 12.0 0.2 2.4 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Utp8 PF10395.9 GAX16014.1 - 0.015 13.9 2.1 0.15 10.6 0.0 2.4 3 0 0 3 3 3 0 Utp8 family TSNAXIP1_N PF15739.5 GAX16014.1 - 0.029 14.7 0.6 0.029 14.7 0.6 2.2 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus YfcL PF08891.11 GAX16014.1 - 0.13 12.6 1.2 0.32 11.4 1.2 1.7 1 1 0 1 1 1 0 YfcL protein Voltage_CLC PF00654.20 GAX16015.1 - 6.9e-58 196.6 26.0 3.5e-57 194.3 20.9 2.9 1 1 1 2 2 2 2 Voltage gated chloride channel HD_3 PF13023.6 GAX16016.1 - 3.7e-36 124.6 0.5 5.9e-35 120.6 0.5 2.0 1 1 0 1 1 1 1 HD domain HD_2 PF12917.7 GAX16016.1 - 1.9e-06 27.7 0.3 6.8e-06 26.0 0.2 1.8 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme DUF2753 PF10952.8 GAX16016.1 - 0.05 13.7 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) HD PF01966.22 GAX16016.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.6 1 1 0 1 1 1 0 HD domain SIR2 PF02146.17 GAX16017.1 - 1.2e-51 175.2 0.0 1.7e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Histone PF00125.24 GAX16018.1 - 3.5e-40 137.4 0.1 3.6e-40 137.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAX16018.1 - 0.024 15.0 0.0 0.036 14.4 0.0 1.2 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 GAX16018.1 - 0.075 13.1 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DRIM PF07539.12 GAX16019.1 - 2.3e-79 267.4 0.9 2.3e-79 267.4 0.9 4.1 5 0 0 5 5 5 1 Down-regulated in metastasis SopA_C PF13979.6 GAX16019.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 SopA-like catalytic domain V-ATPase_H_N PF03224.14 GAX16019.1 - 9.3 5.4 12.0 32 3.7 0.2 4.9 5 0 0 5 5 5 0 V-ATPase subunit H Aminotran_1_2 PF00155.21 GAX16021.1 - 1.6e-65 221.7 0.0 1.8e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAX16021.1 - 0.0029 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 GAX16021.1 - 0.047 12.5 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 GAX16021.1 - 0.062 12.2 0.0 4.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-V Myb_DNA-binding PF00249.31 GAX16022.1 - 8.8e-34 115.5 0.7 1.5e-14 53.9 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX16022.1 - 1.6e-28 98.7 0.1 7.7e-10 38.9 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX16022.1 - 5.6e-05 23.0 0.1 0.0044 16.9 0.3 2.7 1 1 1 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 GAX16022.1 - 0.0063 16.8 1.5 0.69 10.3 0.9 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3517 PF12030.8 GAX16022.1 - 0.033 13.1 0.0 3.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3517) Myb_DNA-bind_4 PF13837.6 GAX16022.1 - 0.25 11.8 4.2 3.1 8.2 0.2 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 GAX16022.1 - 0.35 11.0 2.0 6.2 7.0 0.2 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 GAX16022.1 - 3.2 8.0 8.1 17 5.7 0.1 4.1 3 1 1 4 4 4 0 Rap1 Myb domain MFS_1 PF07690.16 GAX16023.1 - 2.9e-29 102.1 16.0 1.7e-26 93.0 10.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAX16023.1 - 5.1e-05 22.3 4.0 0.0027 16.6 2.0 2.4 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 GAX16023.1 - 7e-05 21.4 1.4 0.00039 18.9 1.1 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector PUCC PF03209.15 GAX16023.1 - 0.00012 21.2 0.5 0.00032 19.8 0.3 1.7 1 1 0 1 1 1 1 PUCC protein EamA PF00892.20 GAX16023.1 - 0.00044 20.4 17.7 3.9 7.6 0.2 4.7 4 1 1 5 5 5 4 EamA-like transporter family DUF3611 PF12263.8 GAX16023.1 - 0.032 14.1 0.5 0.032 14.1 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) OATP PF03137.20 GAX16023.1 - 0.043 12.1 0.1 0.084 11.1 0.1 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UPF0139 PF03669.13 GAX16023.1 - 0.06 13.2 1.5 0.44 10.4 0.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) DUF4227 PF14004.6 GAX16023.1 - 0.083 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) MatE PF01554.18 GAX16023.1 - 7.6 6.2 12.2 1.3 8.7 1.5 3.9 3 2 1 4 4 4 0 MatE DUF1772 PF08592.11 GAX16023.1 - 8 6.8 6.8 1.4 9.2 0.3 3.0 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) AF-4 PF05110.13 GAX16024.1 - 0.093 10.8 0.0 0.11 10.5 0.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LRR_8 PF13855.6 GAX16025.1 - 2.8e-09 36.6 5.2 4.8e-05 23.0 0.8 3.5 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAX16025.1 - 8.4e-09 35.6 7.9 0.021 15.3 0.1 4.7 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAX16025.1 - 0.15 12.2 0.2 32 4.9 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 GAX16025.1 - 0.37 11.5 7.8 15 6.6 0.3 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Mon2_C PF16206.5 GAX16027.1 - 2.1e-13 49.3 2.8 8.3e-11 40.8 1.1 2.3 1 1 1 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 GAX16027.1 - 2.6e-07 30.5 6.9 2.9e-07 30.3 0.0 4.0 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 GAX16027.1 - 0.0006 19.6 2.2 2.1 8.3 0.0 4.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) TSC22 PF01166.18 GAX16027.1 - 0.02 15.2 0.3 0.086 13.2 0.3 2.1 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.15 GAX16027.1 - 0.079 13.1 3.5 0.096 12.8 1.5 2.1 1 1 1 2 2 2 0 Basic region leucine zipper tRNA-synt_2b PF00587.25 GAX16028.1 - 1.6e-30 106.4 0.0 2.3e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAX16028.1 - 4.8e-17 62.2 2.5 9.6e-17 61.2 2.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain WHEP-TRS PF00458.20 GAX16028.1 - 0.031 14.4 1.0 0.074 13.2 1.0 1.6 1 0 0 1 1 1 0 WHEP-TRS domain FapA PF03961.13 GAX16028.1 - 0.071 11.7 1.1 0.1 11.2 1.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Snapin_Pallidin PF14712.6 GAX16028.1 - 0.076 13.4 1.5 0.16 12.4 1.5 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DUF3584 PF12128.8 GAX16028.1 - 0.08 10.5 0.6 0.12 9.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Occludin_ELL PF07303.13 GAX16028.1 - 0.1 13.3 1.0 0.25 12.1 1.0 1.6 1 0 0 1 1 1 0 Occludin homology domain RIFIN PF02009.16 GAX16028.1 - 0.34 10.8 5.0 0.6 9.9 5.0 1.3 1 0 0 1 1 1 0 Rifin GTP_EFTU PF00009.27 GAX16029.1 - 1.1e-51 175.2 0.0 1.7e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX16029.1 - 3.1e-20 72.0 0.0 6.3e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX16029.1 - 1.3e-09 38.3 0.1 4.8e-09 36.5 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX16029.1 - 3.1e-06 27.3 0.1 6.7e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 GAX16029.1 - 0.0048 17.0 0.2 0.015 15.3 0.1 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II Arf PF00025.21 GAX16029.1 - 0.02 14.4 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Septin PF00735.18 GAX16029.1 - 0.022 14.0 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 Septin DUF681 PF05080.12 GAX16029.1 - 0.092 13.4 0.0 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF681) Sec63 PF02889.16 GAX16030.1 - 0.00041 19.6 0.1 0.5 9.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain UPF0542 PF15086.6 GAX16030.1 - 0.036 14.0 1.8 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 HA PF03457.14 GAX16032.1 - 1.3e-39 134.4 2.9 5e-21 74.8 0.4 2.7 2 0 0 2 2 2 2 Helicase associated domain NTPase_I-T PF01931.18 GAX16033.1 - 6.6e-44 149.6 0.0 5.6e-42 143.3 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function DUF84 Nuf2 PF03800.14 GAX16035.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Nuf2 family DUF525 PF04379.14 GAX16036.1 - 1.1e-49 166.6 0.0 3.2e-25 88.2 0.0 2.5 2 0 0 2 2 2 2 ApaG domain Cwf_Cwc_15 PF04889.12 GAX16036.1 - 0.098 12.4 42.3 0.023 14.5 15.9 3.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF4354 PF14263.6 GAX16036.1 - 0.17 11.7 0.0 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) LCD1 PF09798.9 GAX16036.1 - 0.25 9.8 2.3 0.36 9.3 2.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3246 PF11596.8 GAX16036.1 - 0.8 9.1 20.8 0.51 9.7 2.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) SMC_N PF02463.19 GAX16037.1 - 5.2e-61 205.9 10.5 1.5e-60 204.4 10.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAX16037.1 - 2e-23 82.9 0.0 9.6e-23 80.7 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 GAX16037.1 - 4.4e-17 63.2 7.2 4.4e-17 63.2 7.2 6.9 3 2 2 5 5 5 1 AAA domain AAA_21 PF13304.6 GAX16037.1 - 3.6e-14 53.3 4.6 1.2e-06 28.6 0.0 3.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAX16037.1 - 7.1e-10 39.1 10.5 7.1e-10 39.1 10.5 4.5 2 2 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 GAX16037.1 - 6.3e-06 25.8 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 GAX16037.1 - 0.014 15.9 15.8 0.014 15.9 15.8 8.0 2 2 4 7 7 7 0 Apg6 coiled-coil region NDK PF00334.19 GAX16039.1 - 1.2e-39 135.4 0.0 1.6e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SLC12 PF03522.15 GAX16040.1 - 0.66 8.9 8.3 0.68 8.9 8.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Endostatin PF06482.11 GAX16040.1 - 0.66 9.4 11.6 0.87 9.0 11.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CDC45 PF02724.14 GAX16040.1 - 1.5 7.1 13.0 1.6 7.0 13.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GAX16040.1 - 2 8.2 13.5 2.3 8.0 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GAX16040.1 - 5.1 5.7 13.1 5.9 5.5 13.1 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 GAX16040.1 - 6.3 5.2 16.8 8 4.9 16.8 1.4 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 GAX16040.1 - 8.9 6.3 12.0 11 6.0 12.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TPR_2 PF07719.17 GAX16041.1 - 2.8e-09 36.4 11.2 0.00067 19.6 1.3 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16041.1 - 5.2e-09 35.5 9.4 8e-05 22.3 1.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX16041.1 - 5.8e-07 29.6 9.8 0.0002 21.4 2.7 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat STI1 PF17830.1 GAX16041.1 - 1.8e-06 27.8 13.2 0.002 18.0 1.8 2.8 3 0 0 3 3 3 2 STI1 domain TPR_17 PF13431.6 GAX16041.1 - 2.4e-06 27.5 4.4 0.0093 16.3 0.3 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX16041.1 - 2.6e-06 27.9 10.3 2.9e-05 24.6 6.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX16041.1 - 0.00016 22.2 7.0 0.0065 17.2 2.1 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16041.1 - 0.00023 20.8 3.4 0.22 11.3 0.4 3.3 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 GAX16041.1 - 0.0094 16.4 5.6 0.0094 16.4 5.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat RLL PF10036.9 GAX16041.1 - 0.02 14.8 4.7 0.048 13.5 2.1 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein ANAPC3 PF12895.7 GAX16041.1 - 0.028 14.6 1.0 0.057 13.6 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 NACHT_N PF17100.5 GAX16041.1 - 0.034 14.0 6.2 0.063 13.1 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase TPR_8 PF13181.6 GAX16041.1 - 0.055 13.7 0.2 0.055 13.7 0.2 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX16041.1 - 0.079 13.3 8.8 0.12 12.6 4.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX16041.1 - 0.23 12.2 5.9 27 5.7 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat OAD_gamma PF04277.13 GAX16041.1 - 1.6 9.4 5.5 36 5.1 0.1 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Mito_carr PF00153.27 GAX16042.1 - 4.1e-40 135.6 1.7 4.2e-14 52.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1 PF00133.22 GAX16043.1 - 1.9e-193 644.0 0.0 2.4e-193 643.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAX16043.1 - 2.9e-31 108.5 0.0 5.2e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAX16043.1 - 9.2e-20 70.7 0.0 3e-11 42.7 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAX16043.1 - 0.0039 16.7 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAX16043.1 - 0.006 16.0 0.0 0.084 12.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 GAX16043.1 - 0.2 11.5 2.0 0.25 11.3 0.2 2.0 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Pannexin_like PF12534.8 GAX16044.1 - 0.059 12.5 4.5 2.3 7.2 1.5 2.1 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Metallophos PF00149.28 GAX16045.1 - 3.8e-39 135.3 0.2 4.7e-39 135.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAX16045.1 - 0.0045 17.4 0.6 0.012 16.0 0.3 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF3903 PF13043.6 GAX16045.1 - 0.15 11.8 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) Pkinase PF00069.25 GAX16046.1 - 1e-64 218.5 0.0 1.7e-64 217.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16046.1 - 4.2e-31 108.2 0.0 7e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX16046.1 - 2.4e-12 47.1 2.2 1.4e-05 25.5 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX16046.1 - 9.3e-10 37.7 1.0 0.0023 17.7 0.3 3.7 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 GAX16046.1 - 1.4e-09 36.9 2.0 0.0022 17.4 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAX16046.1 - 3.2e-05 23.7 3.4 0.058 13.3 0.3 4.0 1 1 2 3 3 3 2 EF-hand domain pair Pkinase_fungal PF17667.1 GAX16046.1 - 5.6e-05 22.1 0.1 0.0011 17.8 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_5 PF13202.6 GAX16046.1 - 7.3e-05 22.1 0.3 0.028 13.9 0.0 2.6 2 0 0 2 2 2 2 EF hand Kdo PF06293.14 GAX16046.1 - 0.0001 21.7 0.6 0.00025 20.5 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX16046.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX16046.1 - 0.0057 16.0 0.1 0.085 12.1 0.1 2.6 1 1 1 2 2 2 1 Kinase-like Sigma70_r1_1 PF03979.14 GAX16046.1 - 0.087 12.9 0.3 1.4 9.0 0.0 3.0 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 Lysyl_oxidase PF01186.17 GAX16047.1 - 2.3e-30 105.8 0.1 2.3e-30 105.8 0.1 1.6 2 0 0 2 2 2 1 Lysyl oxidase UPF0449 PF15136.6 GAX16049.1 - 1.2 9.6 5.7 0.71 10.4 1.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 CLP1_P PF16575.5 GAX16050.1 - 2.4e-28 99.2 0.0 5.2e-28 98.1 0.0 1.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 GAX16050.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 GAX16050.1 - 0.12 11.9 0.0 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 GAX16050.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 GAX16050.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_membrane_2 PF06472.15 GAX16051.1 - 1.7e-62 211.3 2.3 2.3e-62 210.9 2.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAX16051.1 - 3.3e-20 73.0 0.0 6.6e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 GAX16051.1 - 1e-15 58.0 3.1 4.5e-15 55.9 3.1 1.8 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_membrane PF00664.23 GAX16051.1 - 3.1e-05 23.8 1.4 6.9e-05 22.6 1.4 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 GAX16051.1 - 0.00014 22.3 0.1 0.00052 20.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAX16051.1 - 0.00018 21.2 0.1 0.00052 19.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX16051.1 - 0.00032 20.6 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAX16051.1 - 0.00065 20.0 0.2 0.04 14.2 0.1 2.9 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 GAX16051.1 - 0.0013 18.7 0.0 0.0042 17.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 GAX16051.1 - 0.0014 19.2 0.1 0.004 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX16051.1 - 0.0017 18.1 0.0 0.047 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAX16051.1 - 0.0023 17.8 0.6 0.0083 16.0 0.2 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 GAX16051.1 - 0.0033 16.6 0.2 0.0067 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SMC_N PF02463.19 GAX16051.1 - 0.0049 16.3 0.5 1.2 8.6 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 GAX16051.1 - 0.0081 15.9 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 GAX16051.1 - 0.041 14.0 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 GAX16051.1 - 0.045 13.1 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3902 PF13042.6 GAX16051.1 - 0.078 12.6 1.1 11 5.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3902) SbcCD_C PF13558.6 GAX16051.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 GAX16051.1 - 0.14 11.7 0.1 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF21 PF01595.20 GAX16052.1 - 2.2e-26 92.7 1.6 2.2e-26 92.7 1.6 2.5 3 0 0 3 3 3 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAX16052.1 - 0.0025 18.2 0.2 0.1 13.1 0.0 3.4 2 1 0 2 2 2 1 CBS domain Mntp PF02659.15 GAX16052.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative manganese efflux pump YrhC PF14143.6 GAX16052.1 - 0.14 12.2 1.8 0.39 10.8 1.8 1.7 1 0 0 1 1 1 0 YrhC-like protein Cytadhesin_P30 PF07271.11 GAX16052.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF3995 PF13160.6 GAX16052.1 - 0.15 12.4 1.6 2.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) 2_5_RNA_ligase2 PF13563.6 GAX16053.1 - 1.3e-16 60.9 0.2 2e-09 37.5 0.1 2.6 2 1 0 2 2 2 2 2'-5' RNA ligase superfamily PsaL PF02605.15 GAX16054.1 - 0.037 13.7 1.0 0.25 11.0 1.0 2.0 1 1 0 1 1 1 0 Photosystem I reaction centre subunit XI HemY_N PF07219.13 GAX16054.1 - 0.25 11.5 0.0 0.25 11.5 0.0 2.7 1 1 3 4 4 4 0 HemY protein N-terminus Dynamin_N PF00350.23 GAX16055.1 - 3e-13 50.2 0.3 9e-13 48.6 0.3 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAX16055.1 - 8e-12 45.2 0.1 2.7e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX16055.1 - 6.9e-09 35.5 4.7 2.2e-08 33.9 4.7 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 GAX16055.1 - 1.1e-05 24.9 1.6 0.012 15.1 0.2 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAX16055.1 - 4.6e-05 23.6 0.8 0.0017 18.6 0.1 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 GAX16055.1 - 6.9e-05 22.4 0.7 0.24 10.9 0.2 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.12 GAX16055.1 - 0.00012 21.5 1.7 0.00032 20.1 1.7 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region NOG1 PF06858.14 GAX16055.1 - 0.0005 19.8 0.2 0.012 15.4 0.2 2.5 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) Ras PF00071.22 GAX16055.1 - 0.0013 18.3 0.4 0.044 13.4 0.0 2.6 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 GAX16055.1 - 0.0018 18.2 1.6 2.9 7.8 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase Septin PF00735.18 GAX16055.1 - 0.022 14.0 0.7 0.043 13.1 0.1 1.8 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 GAX16055.1 - 0.038 14.4 1.5 0.34 11.3 0.1 2.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 GAX16055.1 - 0.061 13.6 0.6 0.26 11.5 0.2 2.5 2 1 0 2 2 2 0 AAA domain Focal_AT PF03623.13 GAX16055.1 - 0.11 12.5 2.0 66 3.5 0.4 3.3 2 1 1 3 3 3 0 Focal adhesion targeting region AAA_22 PF13401.6 GAX16055.1 - 0.34 11.2 1.6 13 6.0 0.2 3.3 2 2 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAX16056.1 - 1.4e-12 48.0 0.2 3.8e-12 46.6 0.2 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAX16056.1 - 2.2e-12 47.0 0.1 8.9e-12 45.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX16056.1 - 1.7e-08 34.3 4.4 1.1e-07 31.7 4.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAX16056.1 - 2.4e-05 23.8 1.6 3.9e-05 23.1 0.6 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAX16056.1 - 6.6e-05 22.5 0.8 0.2 11.2 0.2 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Arf PF00025.21 GAX16056.1 - 0.00015 21.3 1.2 0.037 13.5 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAX16056.1 - 0.00024 21.3 0.6 0.011 15.9 0.1 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAX16056.1 - 0.0031 17.5 1.4 1.9 8.4 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase NOG1 PF06858.14 GAX16056.1 - 0.007 16.1 0.8 0.029 14.2 0.5 2.2 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) Ras PF00071.22 GAX16056.1 - 0.0075 15.9 0.9 0.23 11.0 0.1 2.9 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 GAX16056.1 - 0.19 12.1 1.1 1.4 9.2 0.2 2.8 1 1 1 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 GAX16057.1 - 5.2e-15 55.9 0.2 9.3e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAX16057.1 - 9e-13 48.3 0.2 2.7e-12 46.8 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX16057.1 - 1.7e-11 44.0 1.1 5.6e-11 42.3 0.9 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GAX16057.1 - 2.3e-05 24.6 0.3 0.0077 16.4 0.1 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAX16057.1 - 2.8e-05 23.6 0.4 8.3e-05 22.0 0.4 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAX16057.1 - 0.00016 21.3 0.4 0.48 9.9 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Arf PF00025.21 GAX16057.1 - 0.00027 20.4 0.4 0.27 10.7 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 GAX16057.1 - 0.0025 17.4 0.2 0.059 13.0 0.0 2.4 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 GAX16057.1 - 0.0031 17.4 0.4 1.4 8.8 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase NOG1 PF06858.14 GAX16057.1 - 0.023 14.4 0.2 0.068 13.0 0.2 1.9 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_16 PF13191.6 GAX16057.1 - 0.1 13.0 0.7 0.47 10.8 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 GAX16057.1 - 0.13 11.4 1.6 4.6 6.3 1.6 2.7 1 1 0 1 1 1 0 G-protein alpha subunit Bac_surface_Ag PF01103.23 GAX16058.1 - 4.2e-23 82.4 1.1 8.4e-23 81.4 1.1 1.5 1 0 0 1 1 1 1 Surface antigen Med4 PF10018.9 GAX16058.1 - 0.55 9.9 2.4 0.85 9.3 2.4 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 ASF1_hist_chap PF04729.13 GAX16059.1 - 1.2e-59 200.7 0.0 1.5e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF3546 PF12066.8 GAX16061.1 - 1.1e-07 32.0 2.3 1.1e-07 32.0 2.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 GAX16061.1 - 0.005 17.2 0.3 0.011 16.1 0.3 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DpnD-PcfM PF14207.6 GAX16061.1 - 0.096 12.6 0.6 0.25 11.2 0.6 1.7 1 0 0 1 1 1 0 DpnD/PcfM-like protein MIR PF02815.19 GAX16062.1 - 4e-08 33.3 0.1 9.9e-07 28.8 0.1 2.5 1 1 0 1 1 1 1 MIR domain HIP1_clath_bdg PF16515.5 GAX16064.1 - 0.078 13.6 6.7 1.2 9.8 0.8 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 EntA_Immun PF08951.10 GAX16064.1 - 0.11 12.9 0.6 0.28 11.6 0.6 1.6 1 0 0 1 1 1 0 Enterocin A Immunity MTS PF05175.14 GAX16065.1 - 7.8e-14 51.6 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX16065.1 - 8.7e-11 41.7 0.1 2.4e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX16065.1 - 1e-10 42.2 0.0 1.6e-09 38.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 GAX16065.1 - 7.6e-09 36.0 2.8 9.3e-09 35.8 0.4 2.3 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 GAX16065.1 - 1.5e-08 34.6 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX16065.1 - 2.5e-05 24.9 0.0 7.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX16065.1 - 4.5e-05 23.5 0.0 7.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX16065.1 - 8.3e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX16065.1 - 0.00015 21.5 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 GAX16065.1 - 0.00016 22.3 0.0 0.001 19.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 GAX16065.1 - 0.00038 20.2 0.4 0.0011 18.7 0.0 1.8 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.9 GAX16065.1 - 0.00041 20.1 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 GAX16065.1 - 0.0066 16.4 0.1 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAX16065.1 - 0.0071 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_10 PF05971.12 GAX16065.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase GidB PF02527.15 GAX16065.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Eco57I PF07669.11 GAX16065.1 - 0.025 15.1 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 Eco57I restriction-modification methylase NodS PF05401.11 GAX16065.1 - 0.049 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 GAX16065.1 - 0.055 13.1 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase N6_Mtase PF02384.16 GAX16065.1 - 0.13 11.5 0.1 1 8.5 0.1 2.1 1 1 0 1 1 1 0 N-6 DNA Methylase 2OG-FeII_Oxy_3 PF13640.6 GAX16066.1 - 6.3e-15 55.8 0.2 9.9e-15 55.2 0.2 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 GAX16066.1 - 0.00034 21.1 6.2 0.00083 19.8 6.2 1.7 1 0 0 1 1 1 1 ShK domain-like UspB PF10625.9 GAX16066.1 - 0.21 11.6 0.2 0.54 10.3 0.1 1.7 2 0 0 2 2 2 0 Universal stress protein B (UspB) TIP41 PF04176.13 GAX16067.1 - 6e-42 143.0 0.0 1.2e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 TIP41-like family Glutaredoxin PF00462.24 GAX16067.1 - 0.0041 17.3 0.1 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin S6PP_C PF08472.10 GAX16067.1 - 0.015 15.2 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Glyco_trans_1_4 PF13692.6 GAX16068.1 - 2.5e-05 24.7 0.0 0.00077 19.9 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX16068.1 - 0.00025 20.6 0.0 0.0091 15.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAX16068.1 - 0.014 15.8 0.0 0.049 14.0 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferases group 1 Pkinase PF00069.25 GAX16069.1 - 7.4e-58 196.0 0.0 1.3e-57 195.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX16069.1 - 8.9e-34 115.4 0.0 1.2e-16 60.5 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX16069.1 - 2.3e-28 99.2 0.0 3.2e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX16069.1 - 4.1e-08 33.6 3.7 0.0016 18.9 0.3 3.3 2 1 0 2 2 2 2 EF-hand domain pair APH PF01636.23 GAX16069.1 - 1.2e-07 31.9 0.0 0.0061 16.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family EF-hand_8 PF13833.6 GAX16069.1 - 2.1e-07 30.7 1.4 0.00053 19.8 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain pair Kdo PF06293.14 GAX16069.1 - 5.2e-05 22.7 0.0 0.00022 20.7 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_6 PF13405.6 GAX16069.1 - 0.00015 21.5 7.2 0.35 10.9 0.1 5.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 GAX16069.1 - 0.00021 20.6 3.4 0.068 12.8 0.0 3.9 4 0 0 4 4 4 1 EF hand Kinase-like PF14531.6 GAX16069.1 - 0.00081 18.8 0.0 0.0026 17.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like EF-hand_5 PF13202.6 GAX16069.1 - 0.0062 16.0 0.4 0.022 14.2 0.0 2.2 2 0 0 2 2 2 1 EF hand Pkinase_fungal PF17667.1 GAX16069.1 - 0.057 12.2 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Abhydrolase_1 PF00561.20 GAX16070.1 - 5.4e-17 62.3 0.0 1.3e-16 61.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX16070.1 - 6.8e-15 56.3 0.2 9.4e-15 55.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX16070.1 - 3.9e-13 49.2 0.0 5.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 GAX16070.1 - 1.1e-05 24.5 0.0 1.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Thioesterase PF00975.20 GAX16070.1 - 1.4e-05 25.4 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Lipase PF00151.19 GAX16070.1 - 0.00066 19.1 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.25 GAX16070.1 - 0.0008 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 GAX16070.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAX16070.1 - 0.0035 17.1 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 GAX16070.1 - 0.0043 16.7 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 GAX16070.1 - 0.0067 15.2 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family FSH1 PF03959.13 GAX16070.1 - 0.0082 15.8 0.0 0.8 9.3 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF915 PF06028.11 GAX16070.1 - 0.0082 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 GAX16070.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 GAX16070.1 - 0.016 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase BAAT_C PF08840.11 GAX16070.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 GAX16070.1 - 0.041 13.5 0.1 0.093 12.4 0.1 1.8 1 1 0 1 1 1 0 Putative esterase DUF900 PF05990.12 GAX16070.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3530 PF12048.8 GAX16070.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF2974 PF11187.8 GAX16070.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TAFII55_N PF04658.13 GAX16071.1 - 3.5e-19 69.1 1.8 1.2e-18 67.4 0.0 2.3 2 1 0 2 2 2 1 TAFII55 protein conserved region DUF2203 PF09969.9 GAX16071.1 - 0.66 10.7 3.4 9.3 7.0 1.4 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) UPF0176_N PF17773.1 GAX16072.1 - 3.1e-13 49.9 0.0 5.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAX16072.1 - 1.1e-08 35.3 4.4 4.1e-08 33.5 4.4 2.0 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 GAX16072.1 - 0.0037 17.8 0.0 0.011 16.2 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain HA2 PF04408.23 GAX16073.1 - 2.2e-18 66.5 0.6 2.5e-17 63.1 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX16073.1 - 4.2e-16 59.1 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX16073.1 - 2.2e-12 47.3 0.1 1.7e-11 44.5 0.1 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX16073.1 - 3e-07 30.4 0.2 1e-06 28.7 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GAX16073.1 - 0.036 14.4 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Tim17 PF02466.19 GAX16074.1 - 1.6e-11 44.6 5.9 2.9e-11 43.7 5.9 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PX PF00787.24 GAX16075.1 - 0.00069 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 PX domain ubiquitin PF00240.23 GAX16076.1 - 2.5e-19 68.8 0.0 5.6e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 GAX16076.1 - 6.2e-16 58.0 0.1 1.2e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Sod_Ni PF09055.11 GAX16076.1 - 4.3e-10 40.2 0.0 7.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Polysacc_deac_2 PF04748.13 GAX16076.1 - 0.075 12.2 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase TPR_MLP1_2 PF07926.12 GAX16077.1 - 2.6e-16 59.8 23.7 2.6e-16 59.8 23.7 16.3 6 5 6 15 15 15 3 TPR/MLP1/MLP2-like protein ZapB PF06005.12 GAX16077.1 - 0.00019 21.8 7.2 0.00019 21.8 7.2 22.1 7 5 12 19 19 19 3 Cell division protein ZapB MttA_Hcf106 PF02416.16 GAX16077.1 - 0.11 11.8 0.3 0.74 9.2 0.3 2.5 1 0 0 1 1 1 0 mttA/Hcf106 family DUF5631 PF18645.1 GAX16077.1 - 0.24 11.8 2.5 9.5 6.7 0.3 4.3 2 0 0 2 2 2 0 Family of unknown function (DUF5631) Mt_ATP-synt_B PF05405.14 GAX16078.1 - 0.0044 16.6 7.8 0.016 14.8 7.1 2.2 1 1 1 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Macscav_rec PF03523.13 GAX16078.1 - 0.015 15.2 0.2 0.044 13.7 0.2 1.8 1 0 0 1 1 1 0 Macrophage scavenger receptor Nbl1_Borealin_N PF10444.9 GAX16078.1 - 0.45 10.2 4.2 2.7 7.7 0.1 3.5 2 2 2 4 4 4 0 Nbl1 / Borealin N terminal RB_A PF01858.17 GAX16078.1 - 1.4 8.7 7.0 3 7.6 0.5 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain DUF883 PF05957.13 GAX16078.1 - 2.5 8.8 10.5 1.4 9.6 0.3 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) CHDCT2 PF08074.11 GAX16078.1 - 3.7 7.7 7.6 1 9.5 3.9 1.9 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain RVT_2 PF07727.14 GAX16079.1 - 1.3e-08 34.7 0.2 3.2e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX16079.1 - 0.0002 21.5 0.0 0.00067 19.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain MazE_antitoxin PF04014.18 GAX16079.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin DUF4005 PF13178.6 GAX16079.1 - 0.56 10.9 6.1 1.2 9.9 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4005) HAT_KAT11 PF08214.11 GAX16081.1 - 9.7e-33 113.9 0.0 9.7e-33 113.9 0.0 2.5 3 0 0 3 3 3 1 Histone acetylation protein zf-TAZ PF02135.16 GAX16081.1 - 1.5e-25 89.5 37.6 2.6e-16 59.9 14.6 4.9 5 1 0 5 5 5 2 TAZ zinc finger Bromodomain PF00439.25 GAX16081.1 - 9.4e-24 83.3 0.1 1.4e-22 79.5 0.0 2.6 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 GAX16081.1 - 2.4e-08 33.7 6.5 2.4e-08 33.7 6.5 3.8 4 1 1 5 5 5 1 PHD-finger KIX_2 PF16987.5 GAX16081.1 - 1.9e-07 31.0 0.7 1.9e-07 31.0 0.7 2.8 3 1 0 3 3 3 1 KIX domain ZZ PF00569.17 GAX16081.1 - 1.9e-06 27.6 6.3 1.9e-06 27.6 6.3 3.5 4 0 0 4 4 4 1 Zinc finger, ZZ type TPP_enzyme_M_2 PF16582.5 GAX16081.1 - 0.015 15.0 0.2 0.015 15.0 0.2 2.7 3 0 0 3 3 3 0 Middle domain of thiamine pyrophosphate DUF902 PF06001.13 GAX16081.1 - 0.054 14.0 3.5 0.14 12.7 3.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) MmoB_DmpM PF02406.17 GAX16082.1 - 0.091 13.0 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 MmoB/DmpM family tRNA-synt_1b PF00579.25 GAX16083.1 - 5.1e-74 249.2 0.0 7.4e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 GAX16083.1 - 0.00011 21.9 0.1 0.00023 20.8 0.1 1.6 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 GAX16083.1 - 0.0022 17.8 0.0 0.0062 16.3 0.0 1.8 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain PhoD PF09423.10 GAX16084.1 - 2.2e-12 46.7 0.0 5.7e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase PHD PF00628.29 GAX16085.1 - 4.2e-17 61.8 33.2 9.6e-10 38.2 13.7 3.2 2 1 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 GAX16085.1 - 0.00023 20.7 1.8 0.00023 20.7 1.8 3.3 3 1 1 4 4 4 2 PHD-finger C1_2 PF03107.16 GAX16085.1 - 0.0029 17.9 5.6 0.0029 17.9 5.6 4.2 3 1 1 4 4 4 1 C1 domain Rax2 PF12768.7 GAX16087.1 - 0.15 11.5 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Nup96 PF12110.8 GAX16088.1 - 4e-36 124.6 1.2 5.7e-36 124.1 1.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 GAX16088.1 - 1.6e-35 122.4 0.0 5.2e-35 120.8 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 GAX16088.1 - 9.9e-08 32.7 171.6 0.0084 16.9 16.7 8.9 2 2 4 6 6 6 4 Nucleoporin FG repeat region EF-hand_7 PF13499.6 GAX16090.1 - 6.6e-13 48.9 4.5 0.0042 17.5 0.0 5.3 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 GAX16090.1 - 4.6e-10 38.3 0.2 0.032 13.8 0.0 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 GAX16090.1 - 2.2e-09 36.5 0.1 0.57 10.3 0.0 5.8 7 0 0 7 7 7 3 EF-hand domain adh_short PF00106.25 GAX16091.1 - 4.3e-19 68.7 0.0 2.1e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX16091.1 - 7.7e-14 51.8 0.1 1.3e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Spt4 PF06093.13 GAX16091.1 - 0.05 13.7 0.6 0.16 12.1 0.4 2.0 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Glyco_hydro_16 PF00722.21 GAX16092.1 - 8.3e-24 84.0 0.6 1.4e-23 83.2 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAX16092.1 - 4.1e-15 55.2 1.3 5.8e-12 44.8 0.9 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) NicO PF03824.16 GAX16093.1 - 0.03 13.7 1.0 0.033 13.5 0.4 1.4 1 1 0 1 1 1 0 High-affinity nickel-transport protein DinB_2 PF12867.7 GAX16093.1 - 0.12 12.8 7.1 0.18 12.3 7.1 1.3 1 0 0 1 1 1 0 DinB superfamily YgbB PF02542.16 GAX16094.1 - 7.4e-59 198.5 0.0 1e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 YgbB family bZIP_1 PF00170.21 GAX16095.1 - 3.4e-10 39.9 15.8 1.2e-09 38.1 15.5 2.1 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX16095.1 - 3.5e-06 27.0 13.0 9.3e-06 25.6 13.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAX16095.1 - 4e-05 24.0 9.9 0.00083 19.8 10.8 2.5 2 0 0 2 2 2 1 bZIP Maf transcription factor SNF2_N PF00176.23 GAX16096.1 - 5e-68 229.4 0.0 8.4e-68 228.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX16096.1 - 2.7e-10 40.5 0.0 7.4e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX16096.1 - 6.9e-09 35.9 0.0 2.3e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX16096.1 - 6.9e-07 29.2 0.1 2.4e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 GAX16096.1 - 9.6e-07 28.7 5.1 2.9e-06 27.2 5.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX16096.1 - 2.8e-05 24.0 7.9 0.00027 20.8 8.6 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAX16096.1 - 3e-05 24.3 9.4 3e-05 24.3 9.4 2.8 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX16096.1 - 6.2e-05 22.8 1.5 6.2e-05 22.8 1.5 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX16096.1 - 0.00014 21.7 6.7 0.00014 21.7 6.7 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX16096.1 - 0.00032 20.4 4.1 0.00087 19.0 4.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAX16096.1 - 0.0057 16.5 13.4 0.0085 15.9 10.3 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX16096.1 - 0.011 15.6 8.1 0.011 15.6 8.1 2.8 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 Importin_rep_4 PF18808.1 GAX16096.1 - 0.41 11.0 3.7 3 8.2 3.8 2.3 2 0 0 2 2 2 0 Importin repeat FANCL_C PF11793.8 GAX16096.1 - 0.47 10.7 4.2 1.6 9.0 4.2 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 GAX16096.1 - 5.2 7.0 6.1 23 4.9 6.1 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2457 PF10446.9 GAX16096.1 - 5.2 6.1 10.6 7.9 5.5 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nnf1 PF03980.14 GAX16097.1 - 0.00022 21.6 7.7 0.00036 20.9 7.7 1.5 1 1 0 1 1 1 1 Nnf1 DUF445 PF04286.12 GAX16097.1 - 0.016 15.1 3.9 0.02 14.7 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Phage_GP20 PF06810.11 GAX16097.1 - 0.11 12.2 14.9 0.043 13.6 1.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4407 PF14362.6 GAX16097.1 - 0.21 10.9 8.2 0.27 10.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 GAX16097.1 - 0.33 10.9 10.3 0.37 10.7 0.6 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4083 PF13314.6 GAX16097.1 - 0.37 10.8 4.4 0.66 10.0 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Mvb12 PF09452.10 GAX16097.1 - 0.45 11.0 2.0 0.66 10.4 0.2 2.0 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF1068 PF06364.12 GAX16097.1 - 1.1 9.1 8.9 0.043 13.7 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) Csm1_N PF18504.1 GAX16097.1 - 1.2 9.6 13.7 1.8 8.9 6.0 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Herpes_UL6 PF01763.16 GAX16097.1 - 1.4 7.4 5.5 1.6 7.1 0.7 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF4640 PF15480.6 GAX16097.1 - 2.2 8.0 7.5 4.5 6.9 7.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4640) Sec20 PF03908.13 GAX16097.1 - 3.5 7.6 6.3 3.4 7.6 0.9 2.4 2 1 0 2 2 2 0 Sec20 Cep57_CLD_2 PF14197.6 GAX16097.1 - 4.6 7.4 13.4 9 6.5 4.1 2.7 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 adh_short PF00106.25 GAX16098.1 - 6.6e-32 110.6 1.3 8.5e-32 110.2 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX16098.1 - 1.7e-20 73.6 0.1 2.4e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LacAB_rpiB PF02502.18 GAX16098.1 - 0.001 19.1 0.2 0.0028 17.6 0.1 1.7 2 0 0 2 2 2 1 Ribose/Galactose Isomerase Malate_synthase PF01274.22 GAX16099.1 - 2e-187 623.6 0.0 2.3e-187 623.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase UDPG_MGDP_dh PF00984.19 GAX16100.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain SUN PF03856.13 GAX16100.1 - 0.13 11.7 0.2 0.2 11.1 0.2 1.2 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) Pkinase PF00069.25 GAX16104.1 - 6.5e-57 192.9 0.0 1e-56 192.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16104.1 - 1.1e-24 87.2 0.0 3.7e-24 85.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX16104.1 - 0.00013 21.4 0.1 0.0038 16.6 0.1 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAX16104.1 - 0.00069 19.0 1.4 0.0027 17.1 1.4 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 GAX16104.1 - 0.0086 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 GAX16104.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GlcNAc PF11397.8 GAX16105.1 - 1.4e-54 185.9 0.1 1.8e-54 185.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) TPR_2 PF07719.17 GAX16107.1 - 1.3e-08 34.3 1.5 0.0058 16.7 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16107.1 - 1.2e-07 31.2 2.2 0.0012 18.5 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16107.1 - 4.8e-06 26.4 0.7 0.0056 16.8 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16107.1 - 0.001 18.7 0.7 0.32 10.7 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 GAX16107.1 - 0.013 16.2 9.0 0.23 12.4 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX16107.1 - 0.092 12.8 0.7 4.5 7.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX16107.1 - 0.38 11.4 8.0 8.9 7.1 2.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat NSF PF02071.20 GAX16107.1 - 0.56 11.2 1.8 83 4.7 0.1 3.7 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat DUF4205 PF13898.6 GAX16108.1 - 5.1e-39 134.2 0.0 5.5e-35 120.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) SET PF00856.28 GAX16109.1 - 1.4e-15 58.1 2.4 2.8e-15 57.1 0.2 2.7 2 1 0 2 2 2 1 SET domain PHD PF00628.29 GAX16109.1 - 6.7e-07 29.1 10.8 6.7e-07 29.1 10.8 3.6 4 0 0 4 4 4 1 PHD-finger Bromodomain PF00439.25 GAX16109.1 - 7.7e-05 22.7 0.0 0.00025 21.0 0.0 1.9 2 0 0 2 2 2 1 Bromodomain TF_Zn_Ribbon PF08271.12 GAX16109.1 - 0.43 10.1 8.1 3.4 7.3 2.8 3.5 3 0 0 3 3 3 0 TFIIB zinc-binding C1_1 PF00130.22 GAX16109.1 - 5.3 7.0 19.1 0.86 9.5 5.3 3.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_1 PF00583.25 GAX16110.1 - 5.9e-10 39.4 0.2 1.2e-09 38.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX16110.1 - 2.1e-07 30.9 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX16110.1 - 1.6e-06 28.5 0.1 2.7e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAX16110.1 - 8.2e-06 26.5 0.0 1e-05 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 GAX16110.1 - 8.9e-06 25.4 0.1 1.8e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 GAX16110.1 - 0.00016 21.6 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAX16110.1 - 0.00029 21.0 0.0 0.00039 20.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain eIF-1a PF01176.19 GAX16111.1 - 3.9e-23 81.0 0.3 5.5e-23 80.6 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_S8e PF01201.22 GAX16112.1 - 5.4e-54 182.1 0.5 6.2e-54 181.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Autophagy_N PF03986.13 GAX16113.1 - 6.9e-38 129.7 0.6 1.1e-37 129.0 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 GAX16113.1 - 1.2e-18 67.4 0.1 2.5e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 GAX16113.1 - 1.3e-12 46.9 4.5 2.6e-12 46.0 4.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal mTERF PF02536.14 GAX16114.1 - 7.9e-19 67.7 2.0 0.00026 20.0 0.0 4.5 1 1 3 4 4 4 4 mTERF GCHY-1 PF02649.14 GAX16114.1 - 0.053 13.0 0.4 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 Type I GTP cyclohydrolase folE2 Cnd1 PF12717.7 GAX16114.1 - 0.11 12.5 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 TMEM154 PF15102.6 GAX16115.1 - 0.0063 16.4 2.9 0.0074 16.2 0.8 2.3 1 1 2 3 3 3 1 TMEM154 protein family BHD_2 PF10404.9 GAX16115.1 - 0.033 15.1 1.3 0.16 13.0 0.1 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 DUF4033 PF13225.6 GAX16116.1 - 1.7e-34 117.7 0.6 3.5e-34 116.6 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) DUF1798 PF08807.10 GAX16118.1 - 0.16 12.1 0.4 0.37 10.9 0.4 1.5 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Metallophos PF00149.28 GAX16119.1 - 1.4e-08 35.5 4.3 2e-08 35.0 4.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 GAX16119.1 - 7.9e-05 22.9 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain GerD PF17898.1 GAX16120.1 - 0.016 15.1 14.9 0.016 15.1 14.9 2.2 1 1 1 2 2 2 0 Spore germination GerD central core domain Ntox28 PF15605.6 GAX16120.1 - 0.019 15.2 2.5 0.023 14.9 1.6 1.7 1 1 0 1 1 1 0 Bacterial toxin 28 Complex1_LYR PF05347.15 GAX16120.1 - 0.11 12.6 0.7 0.45 10.6 0.7 2.1 1 1 0 1 1 1 0 Complex 1 protein (LYR family) SpoOE-like PF09388.10 GAX16120.1 - 0.15 12.0 3.2 5.1 7.1 0.9 3.1 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein STI1 PF17830.1 GAX16120.1 - 0.17 11.8 19.7 1.8 8.6 6.8 3.2 1 1 2 3 3 3 0 STI1 domain DUF3340 PF11818.8 GAX16120.1 - 0.26 11.4 17.2 0.36 11.0 17.2 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Ndc1_Nup PF09531.10 GAX16120.1 - 1.5 7.4 5.5 1.6 7.3 5.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Not1 PF04054.15 GAX16120.1 - 2.7 6.8 5.6 2.9 6.7 5.6 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 MCU PF04678.13 GAX16120.1 - 3.1 7.8 11.4 3.4 7.7 10.8 1.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF1974 PF09317.11 GAX16120.1 - 3.4 7.1 11.6 4.2 6.9 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) FUSC PF04632.12 GAX16120.1 - 6.1 5.2 5.4 6.9 5.1 5.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ku_C PF03730.14 GAX16120.1 - 7.4 7.3 16.7 5.4 7.8 15.1 1.6 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm Dynamin_N PF00350.23 GAX16120.1 - 7.8 6.5 7.5 8.6 6.4 7.0 1.3 1 1 0 1 1 1 0 Dynamin family DUF883 PF05957.13 GAX16121.1 - 0.41 11.3 3.9 0.78 10.4 2.9 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4239 PF14023.6 GAX16122.1 - 5.2e-51 173.4 0.9 8.7e-51 172.7 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) ADIP PF11559.8 GAX16122.1 - 2 8.5 8.0 0.88 9.6 0.1 3.4 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding Peptidase_A22B PF04258.13 GAX16123.1 - 2.2e-57 194.8 0.9 3.2e-57 194.2 0.9 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 GAX16123.1 - 5.1e-05 23.2 0.0 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 1 PA domain SPP PF06550.11 GAX16123.1 - 3 7.2 8.9 0.64 9.4 0.1 2.5 2 0 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease FMN_red PF03358.15 GAX16124.1 - 1.3e-09 38.0 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 GAX16124.1 - 0.00016 21.9 0.4 0.0016 18.6 0.4 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 GAX16124.1 - 0.027 14.2 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold Golgin_A5 PF09787.9 GAX16126.1 - 9.6e-11 41.7 5.2 9.6e-11 41.7 5.2 3.8 2 1 2 4 4 4 1 Golgin subfamily A member 5 LPP PF04728.13 GAX16126.1 - 0.00037 20.8 3.1 0.00037 20.8 3.1 7.1 8 1 0 8 8 8 2 Lipoprotein leucine-zipper CASP_C PF08172.12 GAX16126.1 - 0.018 14.4 0.2 0.018 14.4 0.2 5.6 3 3 2 5 5 5 0 CASP C terminal UPF0449 PF15136.6 GAX16126.1 - 0.018 15.5 4.8 0.018 15.5 4.8 5.3 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Toxin_trans PF07952.12 GAX16126.1 - 0.17 11.0 1.6 0.29 10.2 1.6 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain TMEM144 PF07857.12 GAX16127.1 - 4.4e-17 62.1 20.8 2.2e-12 46.6 0.3 2.9 2 1 0 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 GAX16127.1 - 0.0001 21.8 20.3 0.024 14.0 3.0 2.2 2 0 0 2 2 2 2 Sugar transport protein TIMELESS PF04821.14 GAX16128.1 - 1.1e-57 195.4 1.5 3e-57 194.0 1.5 1.8 1 0 0 1 1 1 1 Timeless protein RPAP3_C PF13877.6 GAX16128.1 - 0.024 15.2 2.2 0.23 12.0 0.4 3.0 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Vta1 PF04652.16 GAX16128.1 - 1.2 9.1 5.7 0.74 9.8 1.1 3.0 3 1 1 4 4 4 0 Vta1 like LON_substr_bdg PF02190.16 GAX16129.1 - 1.2e-13 51.4 0.0 2.6e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 GAX16129.1 - 4.1e-06 27.0 0.1 2.6e-05 24.4 0.1 2.2 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PQ-loop PF04193.14 GAX16130.1 - 8e-29 99.2 14.0 3.6e-15 55.5 2.0 3.3 3 0 0 3 3 3 2 PQ loop repeat DUF2427 PF10348.9 GAX16130.1 - 0.99 9.2 5.8 0.69 9.7 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) PP2C PF00481.21 GAX16131.1 - 1.8e-39 136.0 0.0 7.6e-19 68.3 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C PH PF00169.29 GAX16131.1 - 5.3e-07 30.1 0.2 3.5e-06 27.5 0.1 2.4 1 1 1 2 2 2 1 PH domain PH_11 PF15413.6 GAX16131.1 - 0.00053 20.4 0.1 0.097 13.1 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain OMP_b-brl_3 PF14905.6 GAX16131.1 - 0.054 12.5 0.7 0.082 11.9 0.7 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family PH_9 PF15410.6 GAX16131.1 - 0.081 13.3 0.0 0.39 11.1 0.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain CDV3 PF15359.6 GAX16131.1 - 0.56 10.7 7.0 6.1 7.3 6.8 2.6 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 TBP PF00352.21 GAX16132.1 - 1.2e-59 198.2 0.6 1.4e-29 101.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) LRR_6 PF13516.6 GAX16133.1 - 8.3e-19 66.0 19.7 0.13 12.3 0.1 11.5 12 0 0 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.7 GAX16133.1 - 8.4e-08 32.4 28.3 0.17 12.3 3.9 7.7 3 3 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX16133.1 - 2e-06 27.5 22.5 5.2 8.0 0.1 9.5 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_8 PF13855.6 GAX16133.1 - 0.029 14.2 25.6 1.5 8.7 0.4 7.8 7 1 1 8 8 8 0 Leucine rich repeat PAP_fibrillin PF04755.12 GAX16134.1 - 1.1e-15 58.1 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin Hemerythrin PF01814.23 GAX16135.1 - 1.5e-05 25.6 1.6 0.0069 17.0 0.1 2.2 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain Dynactin_p22 PF07426.11 GAX16135.1 - 0.011 15.6 0.6 0.6 10.0 0.1 2.2 2 0 0 2 2 2 0 Dynactin subunit p22 Cytochrom_B562 PF07361.11 GAX16135.1 - 0.26 11.9 4.6 10 6.9 1.7 2.4 2 0 0 2 2 2 0 Cytochrome b562 Rubredoxin_2 PF18073.1 GAX16138.1 - 0.071 12.8 0.4 0.071 12.8 0.4 3.8 4 0 0 4 4 4 0 Rubredoxin metal binding domain MutS_V PF00488.21 GAX16139.1 - 2.6e-70 236.3 0.0 4.5e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAX16139.1 - 8e-29 101.2 0.0 1.6e-28 100.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAX16139.1 - 8.2e-29 100.1 0.1 1.9e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GAX16139.1 - 0.0014 18.9 0.0 0.017 15.4 0.0 2.7 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 GAX16139.1 - 0.0049 17.2 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV CDC45 PF02724.14 GAX16139.1 - 1.6 7.0 7.2 2.4 6.3 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein MMS1_N PF10433.9 GAX16140.1 - 2.6e-115 385.9 0.0 7.5e-115 384.3 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAX16140.1 - 1.9e-75 254.2 0.0 3.8e-75 253.2 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region NOA36 PF06524.12 GAX16140.1 - 5.2 6.3 7.9 8.8 5.5 7.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF974 PF06159.13 GAX16141.1 - 1.6e-42 146.0 0.0 2.2e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 GAX16141.1 - 0.15 11.4 0.2 5.8 6.2 0.1 2.6 2 1 1 3 3 3 0 TRAPP trafficking subunit Trs65 CitMHS PF03600.16 GAX16142.1 - 8.3e-27 94.2 2.9 1.2e-26 93.6 1.3 1.9 1 1 1 2 2 2 1 Citrate transporter PDR_CDR PF06422.12 GAX16142.1 - 0.07 13.0 5.8 2.7 8.0 0.1 3.0 2 0 0 2 2 2 0 CDR ABC transporter Aminotran_1_2 PF00155.21 GAX16143.1 - 8e-53 179.9 0.0 9.6e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAX16143.1 - 4e-07 29.6 0.2 1.4e-06 27.8 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAX16143.1 - 7.2e-07 28.8 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAX16143.1 - 3.7e-05 22.9 0.0 5.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 GAX16143.1 - 0.00024 20.0 0.0 0.00038 19.3 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 GAX16143.1 - 0.0014 17.2 0.0 0.0027 16.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme BSD PF03909.17 GAX16144.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 BSD domain CCT PF06203.14 GAX16145.1 - 1.2e-15 57.3 10.6 2.7e-15 56.1 10.6 1.6 1 0 0 1 1 1 1 CCT motif NARP1 PF12569.8 GAX16145.1 - 0.66 8.8 7.9 0.98 8.2 7.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U1snRNP70_N PF12220.8 GAX16145.1 - 2.2 9.0 8.4 8 7.2 7.7 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CortBP2 PF09727.9 GAX16145.1 - 3.7 7.4 12.7 0.82 9.5 9.2 1.6 2 0 0 2 2 2 0 Cortactin-binding protein-2 Peptidase_S49_N PF08496.10 GAX16145.1 - 8.8 6.4 8.8 24 5.0 8.8 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sgf11 PF08209.11 GAX16146.1 - 9.3e-13 47.5 0.0 1.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 GAX16146.1 - 0.0025 17.7 0.2 0.0037 17.1 0.2 1.3 1 0 0 1 1 1 1 zinc-finger of a C2HC-type CUE PF02845.16 GAX16147.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain EMC1_C PF07774.13 GAX16148.1 - 1.1e-58 198.4 0.0 1.8e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 GAX16148.1 - 3.3e-05 23.6 0.8 3.3e-05 23.6 0.8 2.4 3 1 0 3 3 3 1 PQQ-like domain Clostridium_P47 PF06597.11 GAX16148.1 - 0.058 12.1 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Clostridium P-47 protein Cupin_4 PF08007.12 GAX16149.1 - 2.3e-15 56.9 0.1 2e-14 53.8 0.1 2.2 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 GAX16149.1 - 8.3e-12 45.4 0.0 2.3e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 GAX16149.1 - 0.0023 17.6 0.1 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 Cupin domain Phostensin_N PF13916.6 GAX16149.1 - 0.13 12.6 0.0 0.48 10.8 0.0 2.1 1 1 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal 5_nucleotid PF05761.14 GAX16150.1 - 2.8e-109 366.0 0.1 2.5e-78 264.0 0.0 2.1 2 0 0 2 2 2 2 5' nucleotidase family Hydrolase_like PF13242.6 GAX16150.1 - 0.012 15.6 0.0 0.039 14.0 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like ABC2_membrane PF01061.24 GAX16151.1 - 3.3e-68 229.2 62.5 2.2e-36 125.2 22.3 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAX16151.1 - 7.9e-43 146.3 0.1 9.1e-22 78.1 0.1 2.6 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 GAX16151.1 - 1.2e-07 31.8 0.5 0.00049 20.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 GAX16151.1 - 1.7e-07 31.0 1.3 0.00088 18.9 0.6 3.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 GAX16151.1 - 1.7e-07 30.8 1.5 0.0086 15.8 0.6 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GAX16151.1 - 2.7e-07 30.7 0.0 0.51 10.1 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAX16151.1 - 3.8e-06 27.2 0.1 0.05 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAX16151.1 - 9e-06 26.2 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 GAX16151.1 - 9.4e-06 26.3 0.3 0.15 12.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.19 GAX16151.1 - 0.00014 21.3 1.0 1.2 8.5 0.1 3.9 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 GAX16151.1 - 0.00017 20.9 14.4 0.00017 20.9 14.4 3.6 3 2 1 4 4 3 1 ABC-2 family transporter protein AAA_18 PF13238.6 GAX16151.1 - 0.0002 21.9 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAX16151.1 - 0.00022 21.2 1.2 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.12 GAX16151.1 - 0.00042 19.7 0.8 0.072 12.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 GAX16151.1 - 0.00051 20.2 0.3 1.1 9.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 GAX16151.1 - 0.0012 18.5 0.7 1.1 8.8 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAX16151.1 - 0.0027 17.5 5.2 0.5 10.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 GAX16151.1 - 0.0032 17.5 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 GAX16151.1 - 0.0036 17.2 0.7 0.29 11.0 0.0 2.9 3 0 0 3 3 2 1 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 GAX16151.1 - 0.0055 17.0 0.4 0.51 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX16151.1 - 0.0059 16.3 1.7 2.6 7.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 GAX16151.1 - 0.0069 16.8 1.2 2.7 8.4 0.0 3.2 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.17 GAX16151.1 - 0.0075 16.0 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 GAX16151.1 - 0.0088 15.6 1.0 4.2 6.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 GAX16151.1 - 0.013 15.4 1.0 4.7 7.2 0.2 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 GAX16151.1 - 0.015 15.7 2.4 3.2 8.2 0.0 3.7 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX16151.1 - 0.017 14.8 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GAX16151.1 - 0.026 14.8 1.7 7.4 6.8 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAX16151.1 - 0.032 14.7 0.7 1.3 9.5 0.1 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 GAX16151.1 - 0.048 12.8 1.3 1.4 8.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 GAX16151.1 - 0.049 13.6 0.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MeaB PF03308.16 GAX16151.1 - 0.09 11.7 0.1 0.86 8.5 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 GAX16151.1 - 0.093 11.9 0.1 0.63 9.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 GAX16151.1 - 0.098 12.4 1.5 1.4 8.6 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 GAX16151.1 - 0.12 12.2 0.2 5.3 6.9 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_15 PF13175.6 GAX16151.1 - 0.17 11.5 0.1 22 4.6 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 GAX16151.1 - 0.19 11.0 0.8 0.82 9.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pro-kuma_activ PF09286.11 GAX16151.1 - 0.23 11.8 0.9 3.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain Viral_helicase1 PF01443.18 GAX16151.1 - 0.24 11.1 0.4 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 GAX16151.1 - 0.25 10.6 1.3 22 4.3 0.0 2.7 3 0 0 3 3 3 0 KaiC DUF87 PF01935.17 GAX16151.1 - 0.45 10.6 9.2 0.87 9.6 0.2 3.0 3 1 1 4 4 3 0 Helicase HerA, central domain DUF5056 PF16479.5 GAX16151.1 - 0.47 10.7 3.4 18 5.6 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) GLTP PF08718.11 GAX16152.1 - 4.7e-18 65.9 0.0 1.3e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GLTP PF08718.11 GAX16153.1 - 4e-15 56.4 0.0 9.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Apo-CIII PF05778.12 GAX16153.1 - 0.08 12.6 0.2 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) NIF PF03031.18 GAX16154.1 - 2.5e-43 147.5 0.0 3.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 GAX16154.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF3323 PF11796.8 GAX16154.1 - 2.4 8.0 7.6 0.41 10.5 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Proteasome PF00227.26 GAX16155.1 - 1.5e-47 161.5 0.1 2.9e-47 160.6 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX16155.1 - 1.8e-13 49.9 0.1 3.1e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MtN3_slv PF03083.16 GAX16156.1 - 6.1e-23 80.7 2.6 7e-14 51.6 0.6 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF3054 PF11255.8 GAX16156.1 - 2.1 8.9 7.1 0.66 10.5 0.4 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3054) zf-SNAP50_C PF12251.8 GAX16157.1 - 1.1e-14 54.6 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal IFT81_CH PF18383.1 GAX16157.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain zinc-ribbons_6 PF07191.12 GAX16157.1 - 0.12 12.3 3.9 0.32 11.0 3.9 1.7 1 0 0 1 1 1 0 zinc-ribbons zf-C3HC4_3 PF13920.6 GAX16157.1 - 7.2 6.6 10.7 10 6.1 7.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EF-hand_7 PF13499.6 GAX16158.1 - 0.15 12.5 0.1 0.34 11.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 GAX16158.1 - 0.16 11.6 0.4 1.1 9.0 0.1 2.3 1 1 1 2 2 2 0 EF hand HisKA PF00512.25 GAX16158.1 - 0.3 11.1 1.4 4.5 7.4 1.4 2.4 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain HSF_DNA-bind PF00447.17 GAX16160.1 - 1.8e-10 41.3 0.0 2.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding RICTOR_V PF14668.6 GAX16161.1 - 0.0012 19.0 0.0 0.078 13.2 0.0 3.0 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.23 GAX16161.1 - 0.023 14.7 12.8 5.1 7.3 0.0 6.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 GAX16162.1 - 1.5e-27 96.0 0.1 9.5e-10 38.9 0.0 6.2 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAX16162.1 - 9.8e-18 63.7 3.2 4.1 8.0 0.0 10.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 GAX16162.1 - 1.2e-17 64.0 0.3 0.13 12.8 0.0 9.2 7 2 3 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX16162.1 - 8e-17 59.6 4.8 0.71 10.6 0.0 10.6 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 GAX16162.1 - 3.1e-12 46.5 0.9 0.32 11.4 0.0 7.3 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Proteasome PF00227.26 GAX16165.1 - 2.7e-44 150.9 0.1 3.6e-44 150.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX16165.1 - 3.4e-09 36.2 1.4 3.9e-09 36.0 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 GAX16165.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) COQ9 PF08511.11 GAX16165.1 - 0.034 13.9 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 COQ9 DAHP_synth_2 PF01474.16 GAX16166.1 - 3.6e-193 642.0 0.0 4.1e-193 641.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Tsi6 PF18660.1 GAX16166.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Tsi6 Chloroa_b-bind PF00504.21 GAX16167.1 - 4.2e-20 72.9 0.0 8.4e-20 71.9 0.0 1.5 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Inositol_P PF00459.25 GAX16168.1 - 5.4e-31 108.1 0.1 1.7e-30 106.5 0.1 1.8 1 1 1 2 2 2 1 Inositol monophosphatase family CN_hydrolase PF00795.22 GAX16168.1 - 0.077 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase PBP1_TM PF14812.6 GAX16168.1 - 0.13 12.6 4.4 0.25 11.7 4.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Inositol_P PF00459.25 GAX16169.1 - 1.1e-56 192.4 0.0 1.3e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 GAX16169.1 - 0.029 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain TAXi_N PF14543.6 GAX16170.1 - 5.6e-19 69.1 0.3 5.6e-19 69.1 0.3 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX16170.1 - 3.3e-15 56.3 1.1 6.6e-10 38.9 0.4 2.9 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX16170.1 - 0.00012 21.9 0.1 0.056 13.2 0.0 2.5 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal EcKinase PF02958.20 GAX16171.1 - 4.2e-15 55.8 0.0 3.2e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 GAX16171.1 - 2.8e-11 43.8 0.1 3.9e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAX16171.1 - 0.0021 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 GAX16171.1 - 0.16 11.3 0.1 0.92 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Abhydrolase_6 PF12697.7 GAX16172.1 - 2.3e-22 80.7 0.1 3.5e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX16172.1 - 1.3e-17 63.8 0.0 2.6e-17 62.9 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX16172.1 - 9.1e-09 35.3 0.1 0.00018 21.3 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold UPF0227 PF05728.12 GAX16172.1 - 0.0031 17.5 0.0 0.078 12.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 GAX16172.1 - 0.0045 16.8 0.0 0.24 11.2 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GAX16172.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain HopJ PF08888.11 GAX16173.1 - 1.8e-39 134.3 0.0 2.5e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 HopJ type III effector protein CvfB_WH PF17783.1 GAX16174.1 - 1.5e-16 59.9 0.0 2.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 CvfB-like winged helix domain Exo_endo_phos PF03372.23 GAX16175.1 - 2.2e-23 83.0 0.5 5.2e-23 81.8 0.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 GAX16175.1 - 0.01 16.1 3.3 0.022 15.0 3.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Exo_endo_phos_2 PF14529.6 GAX16175.1 - 0.069 13.0 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase His_Phos_2 PF00328.22 GAX16176.1 - 4.3e-09 36.2 0.0 7.1e-07 28.9 0.0 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF4792 PF16040.5 GAX16177.1 - 8.4e-06 25.6 0.7 2.9e-05 23.9 0.1 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4792) DUF4793 PF16041.5 GAX16177.1 - 2.3e-05 24.5 0.2 5.6e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) PAP_fibrillin PF04755.12 GAX16178.1 - 1.2e-11 44.9 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin DAGAT PF03982.13 GAX16179.1 - 9.2e-44 149.5 0.0 1.1e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GAX16179.1 - 1.3e-07 31.3 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ABC_membrane_2 PF06472.15 GAX16179.1 - 0.021 14.2 0.1 0.12 11.7 0.1 2.0 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 DAGAT PF03982.13 GAX16180.1 - 1.3e-39 135.9 0.2 1.7e-39 135.6 0.2 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GAX16180.1 - 5e-05 22.9 0.0 9e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Methyltransf_3 PF01596.17 GAX16181.1 - 4.5e-12 45.6 0.0 1.3e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAX16181.1 - 3.5e-06 28.0 0.0 8.3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Proteasome PF00227.26 GAX16182.1 - 8.4e-25 87.4 0.0 1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit BphX PF06139.12 GAX16183.1 - 0.2 11.6 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 BphX-like IMPDH PF00478.25 GAX16185.1 - 1.5e-134 448.4 1.2 1.7e-134 448.2 1.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 GAX16185.1 - 5.7e-13 49.1 0.0 3.1e-05 24.3 0.0 3.5 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 GAX16185.1 - 5.9e-10 39.1 2.0 5.2e-07 29.4 0.3 2.4 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 GAX16185.1 - 1.9e-06 27.1 14.1 4.8e-05 22.6 12.3 2.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 GAX16185.1 - 0.00023 20.6 3.5 0.024 14.0 0.6 2.5 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAX16185.1 - 0.0028 17.1 0.5 0.021 14.3 0.5 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 GAX16185.1 - 0.0034 16.6 2.6 0.11 11.6 2.6 3.1 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 GAX16185.1 - 0.014 14.6 3.7 0.036 13.2 1.3 2.3 2 0 0 2 2 2 0 Conserved region in glutamate synthase Aldolase PF01081.19 GAX16185.1 - 0.023 14.1 1.5 0.096 12.1 0.1 2.4 3 0 0 3 3 3 0 KDPG and KHG aldolase TMP-TENI PF02581.17 GAX16185.1 - 0.038 13.3 1.0 1.5 8.1 0.5 2.4 1 1 1 2 2 2 0 Thiamine monophosphate synthase MFS_5 PF05631.14 GAX16186.1 - 7.5e-77 258.6 4.6 1.2e-76 258.0 4.6 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAX16186.1 - 1.3e-16 60.5 20.1 1.3e-16 60.5 20.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX16186.1 - 6.3e-06 25.3 0.6 6.3e-06 25.3 0.6 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 GAX16186.1 - 0.00064 18.4 1.8 0.00064 18.4 1.8 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein TMF_TATA_bd PF12325.8 GAX16187.1 - 7.6e-05 22.9 5.8 7.6e-05 22.9 5.8 11.9 7 3 3 12 12 12 2 TATA element modulatory factor 1 TATA binding DUF3481 PF11980.8 GAX16187.1 - 0.068 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein UvrA_DNA-bind PF17755.1 GAX16187.1 - 0.23 11.8 10.3 0.37 11.2 0.3 4.3 4 1 0 4 4 4 0 UvrA DNA-binding domain Img2 PF05046.14 GAX16187.1 - 0.6 10.4 5.5 1.8 8.9 0.1 4.4 4 0 0 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) zf-MYND PF01753.18 GAX16188.1 - 2.4e-06 27.5 13.7 5.4e-06 26.4 13.7 1.6 1 0 0 1 1 1 1 MYND finger TMEM151 PF14857.6 GAX16188.1 - 0.0063 15.5 0.2 0.0097 14.9 0.2 1.2 1 0 0 1 1 1 1 TMEM151 family CEBP_ZZ PF16366.5 GAX16188.1 - 2.1 8.6 12.7 1.1 9.6 10.2 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain TPR_14 PF13428.6 GAX16189.1 - 2.6e-09 37.1 7.0 0.012 16.4 0.0 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX16189.1 - 9.1e-07 29.3 5.1 0.2 12.2 0.1 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16189.1 - 3.4e-05 23.6 13.5 3.2 8.1 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16189.1 - 0.00052 20.0 4.1 60 4.2 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX16189.1 - 0.0013 19.3 12.7 4.8 7.9 2.4 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX16189.1 - 0.0022 18.2 1.2 0.0022 18.2 1.2 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16189.1 - 0.075 12.7 0.9 0.9 9.3 0.0 3.2 4 0 0 4 4 4 0 TPR repeat TPR_17 PF13431.6 GAX16189.1 - 0.078 13.4 0.6 35 5.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX16189.1 - 0.41 10.6 9.7 0.94 9.4 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAX16190.1 - 0.12 12.2 2.1 5.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF440 PF04269.12 GAX16190.1 - 2.4 8.5 8.7 0.59 10.4 1.1 3.0 3 1 0 3 3 3 0 Protein of unknown function, DUF440 APH PF01636.23 GAX16190.1 - 6.1 6.7 8.1 0.5 10.2 0.4 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family NIF PF03031.18 GAX16191.1 - 3.5e-53 179.5 0.3 5.1e-53 179.0 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAX16191.1 - 0.00076 19.9 0.2 0.0052 17.2 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Sec23_trunk PF04811.15 GAX16193.1 - 1.5e-54 185.2 0.0 1.3e-53 182.0 0.0 2.0 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX16193.1 - 1e-24 86.3 0.6 2.7e-24 84.9 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAX16193.1 - 6.1e-23 81.4 0.0 1.4e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAX16193.1 - 2.1e-16 59.6 7.6 4.3e-16 58.7 7.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAX16193.1 - 2.4e-10 40.2 0.0 4.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAX16193.1 - 0.014 14.8 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TPR_15 PF13429.6 GAX16196.1 - 0.0014 17.9 0.0 0.0033 16.7 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16196.1 - 0.066 13.4 0.9 1.2 9.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 GAX16197.1 - 5.1e-13 49.6 0.0 1.1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 GAX16197.1 - 4.7e-11 42.7 0.1 4.7e-11 42.7 0.1 2.1 2 1 0 2 2 1 1 AAA lid domain Mg_chelatase PF01078.21 GAX16197.1 - 0.00034 20.1 0.3 0.004 16.6 0.2 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 GAX16197.1 - 0.0013 19.1 0.7 0.024 15.0 0.4 3.0 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GAX16197.1 - 0.0022 18.3 1.8 0.34 11.2 0.2 2.9 2 1 1 3 3 3 1 AAA domain NTPase_1 PF03266.15 GAX16197.1 - 0.0024 17.8 0.2 0.0054 16.7 0.2 1.6 1 0 0 1 1 1 1 NTPase CbiA PF01656.23 GAX16197.1 - 0.0027 17.8 1.2 0.039 14.0 0.1 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 GAX16197.1 - 0.0037 17.3 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ComJ PF11033.8 GAX16197.1 - 0.0066 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Competence protein J (ComJ) AAA_5 PF07728.14 GAX16197.1 - 0.0069 16.4 0.7 0.018 15.1 0.1 2.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAX16197.1 - 0.0073 16.0 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 GAX16197.1 - 0.009 15.8 0.5 0.021 14.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 GAX16197.1 - 0.014 14.7 1.1 0.13 11.5 1.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.12 GAX16197.1 - 0.016 14.8 0.7 0.89 9.2 0.1 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Viral_helicase1 PF01443.18 GAX16197.1 - 0.017 14.9 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Nsp1_C PF05064.13 GAX16197.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region RNA_helicase PF00910.22 GAX16197.1 - 0.022 15.1 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 GAX16197.1 - 0.024 13.6 0.1 0.047 12.6 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 GAX16197.1 - 0.027 14.7 0.1 0.027 14.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX16197.1 - 0.031 14.8 0.0 0.031 14.8 0.0 3.6 3 1 1 4 4 4 0 AAA domain KTI12 PF08433.10 GAX16197.1 - 0.041 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MipZ PF09140.11 GAX16197.1 - 0.042 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase MipZ APS_kinase PF01583.20 GAX16197.1 - 0.049 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 GAX16197.1 - 0.058 13.0 1.1 0.48 10.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX16197.1 - 0.071 13.3 0.0 0.071 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 GAX16197.1 - 0.097 11.6 0.1 0.21 10.5 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAX16197.1 - 0.14 12.6 2.6 0.24 11.7 0.1 2.3 2 1 1 3 3 3 0 AAA ATPase domain AAA_11 PF13086.6 GAX16197.1 - 0.23 11.2 1.2 0.73 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain UCH PF00443.29 GAX16198.1 - 4.2e-47 160.8 0.0 9.5e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX16198.1 - 2.9e-16 60.0 6.4 3.6e-15 56.4 0.1 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Fer4_10 PF13237.6 GAX16198.1 - 0.88 9.7 4.2 3.1 8.0 4.2 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain Peptidase_C2 PF00648.21 GAX16199.1 - 1.4e-37 129.3 0.0 2.6e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.18 GAX16199.1 - 8.1e-06 25.8 10.6 0.00025 21.0 0.5 2.6 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 GAX16199.1 - 2e-05 24.9 0.0 0.033 14.5 0.0 2.5 2 0 0 2 2 2 2 Calpain large subunit, domain III ANAPC4_WD40 PF12894.7 GAX16200.1 - 2.4e-33 114.3 0.0 1.2e-06 28.7 0.0 11.4 3 2 9 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX16200.1 - 3.3e-16 59.4 25.8 0.17 12.8 0.2 11.8 13 0 0 13 13 13 4 WD domain, G-beta repeat WD40_like PF17005.5 GAX16200.1 - 1.5e-11 44.2 0.0 0.0073 15.7 0.0 5.4 5 2 1 6 6 6 3 WD40-like domain BBS2_Mid PF14783.6 GAX16200.1 - 7.1e-05 22.8 0.0 6.9 6.8 0.0 5.2 5 1 1 6 6 6 1 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.6 GAX16200.1 - 9.1e-05 21.9 0.1 0.077 12.2 0.1 4.1 3 2 2 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 GAX16200.1 - 0.0053 15.1 0.0 2.4 6.3 0.1 3.4 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz TFIIIC_delta PF12657.7 GAX16200.1 - 0.017 15.1 9.3 0.27 11.2 2.2 4.6 4 2 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Kelch_1 PF01344.25 GAX16200.1 - 0.085 12.5 0.0 17 5.1 0.0 3.6 3 0 0 3 3 3 0 Kelch motif PD40 PF07676.12 GAX16200.1 - 0.16 11.9 6.5 4.2 7.4 0.2 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Aldo_ket_red PF00248.21 GAX16201.1 - 4.6e-27 95.0 0.0 1.4e-25 90.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DHHC PF01529.20 GAX16201.1 - 0.048 13.8 0.4 0.1 12.7 0.4 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase zf-MIZ PF02891.20 GAX16202.1 - 4.8e-15 55.0 1.8 8.9e-15 54.2 1.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 GAX16202.1 - 3.3e-05 23.6 0.1 9.3e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit vATP-synt_E PF01991.18 GAX16202.1 - 0.2 11.1 8.3 0.35 10.2 8.3 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit GST_N PF02798.20 GAX16203.1 - 4.9e-12 46.0 0.0 9.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAX16203.1 - 4.9e-11 42.9 0.0 9.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX16203.1 - 5.8e-08 32.9 0.1 1e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX16203.1 - 9.1e-05 22.4 0.0 0.00028 20.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX16203.1 - 0.00059 20.0 0.1 0.0028 17.8 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAX16203.1 - 0.007 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 GAX16203.1 - 0.15 12.8 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain MatE PF01554.18 GAX16204.1 - 4.5e-14 52.4 7.4 4.5e-14 52.4 7.4 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAX16204.1 - 5.2e-06 26.6 10.7 5.2e-06 26.6 10.7 3.2 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF3927 PF13064.6 GAX16204.1 - 0.07 13.1 0.6 0.33 10.9 0.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) RETICULATA-like PF11891.8 GAX16205.1 - 1.7e-42 145.3 0.7 2.1e-42 145.0 0.7 1.1 1 0 0 1 1 1 1 Protein RETICULATA-related FA_hydroxylase PF04116.13 GAX16206.1 - 6.9e-17 62.0 8.1 6.9e-17 62.0 8.1 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ELO PF01151.18 GAX16207.1 - 1.7e-49 168.6 25.7 2.5e-49 168.1 25.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family TPT PF03151.16 GAX16208.1 - 1.6e-93 313.2 6.7 2e-93 313.0 6.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX16208.1 - 3.7e-16 59.5 17.4 1.6e-08 34.8 4.1 2.9 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.11 GAX16208.1 - 0.016 14.5 7.1 0.09 12.0 7.1 1.9 1 1 0 1 1 1 0 UAA transporter family GTP_EFTU PF00009.27 GAX16209.1 - 6.3e-29 100.9 0.1 1.3e-28 99.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAX16209.1 - 5.4e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAX16209.1 - 2.4e-05 23.8 0.3 0.00027 20.4 0.3 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 GAX16209.1 - 0.00038 20.8 0.5 0.0048 17.3 0.1 3.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RIBIOP_C PF04950.12 GAX16209.1 - 0.00047 19.7 3.0 0.0008 18.9 0.3 2.1 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal ATP_bind_1 PF03029.17 GAX16209.1 - 0.014 15.2 0.3 7.1 6.3 0.1 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 GAX16209.1 - 0.02 14.8 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 GAX16209.1 - 0.026 14.3 0.1 0.57 10.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 GAX16209.1 - 0.35 10.5 1.2 2.9 7.5 0.1 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FSH1 PF03959.13 GAX16210.1 - 7.5e-13 48.6 0.0 3.1e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) FAM176 PF14851.6 GAX16210.1 - 0.071 12.8 0.3 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 FAM176 family Rhomboid PF01694.22 GAX16211.1 - 4.5e-30 104.6 19.0 4.5e-30 104.6 19.0 1.9 2 0 0 2 2 2 1 Rhomboid family Zn-ribbon_8 PF09723.10 GAX16211.1 - 0.067 13.3 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Sulfotransfer_3 PF13469.6 GAX16213.1 - 2.6e-36 126.1 0.0 8.2e-36 124.4 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 GAX16213.1 - 7.3e-13 48.6 0.0 2.1e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain TPR_1 PF00515.28 GAX16213.1 - 5.7e-06 25.9 0.0 0.003 17.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16213.1 - 2.3e-05 24.1 0.2 0.031 14.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX16213.1 - 0.0052 17.4 0.0 0.022 15.4 0.0 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX16213.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16213.1 - 0.043 14.0 0.0 1.3 9.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX16213.1 - 0.06 13.7 1.3 8.9 6.7 0.0 3.0 2 1 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX16213.1 - 0.06 13.7 0.0 1.7 9.2 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX16213.1 - 0.098 13.2 0.3 2.7 8.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16213.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.9 1 1 0 1 1 1 0 TPR repeat UCH PF00443.29 GAX16214.1 - 3.1e-47 161.3 0.0 5e-47 160.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX16214.1 - 6.5e-17 62.1 0.0 1.1e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CFIA_Pcf11 PF11526.8 GAX16214.1 - 0.77 10.3 4.2 0.47 11.0 1.6 1.9 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Thioredoxin PF00085.20 GAX16215.1 - 0.00091 19.2 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 GAX16216.1 - 2.6e-19 69.1 0.3 6.4e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX16216.1 - 1.4e-06 28.7 0.8 3.1e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAX16216.1 - 0.0018 18.2 0.4 0.0079 16.1 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 GAX16216.1 - 0.0028 17.8 0.5 0.0073 16.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like DUF3972 PF13118.6 GAX16216.1 - 0.0029 18.0 1.3 0.0047 17.4 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) Redoxin PF08534.10 GAX16216.1 - 0.0065 16.2 0.2 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Redoxin OST3_OST6 PF04756.13 GAX16216.1 - 0.0098 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAX16216.1 - 0.012 15.9 0.9 0.083 13.2 0.1 2.4 2 1 1 3 3 3 0 Thioredoxin-like Thioredoxin_6 PF13848.6 GAX16216.1 - 0.029 14.3 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain MinC_N PF05209.13 GAX16216.1 - 0.031 14.2 0.0 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain DUF5098 PF17023.5 GAX16216.1 - 0.058 12.4 4.0 0.084 11.8 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) FapA PF03961.13 GAX16216.1 - 0.076 11.6 1.9 0.099 11.2 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PET117 PF15786.5 GAX16217.1 - 0.033 14.4 1.4 0.033 14.4 1.4 2.1 2 1 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Dishevelled PF02377.15 GAX16217.1 - 0.12 12.9 9.5 0.18 12.3 9.5 1.3 1 0 0 1 1 1 0 Dishevelled specific domain HA PF03457.14 GAX16219.1 - 7.2e-42 141.6 0.3 3.6e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Helicase associated domain RRN3 PF05327.11 GAX16219.1 - 0.14 10.7 0.1 0.16 10.5 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NUC173 PF08161.12 GAX16220.1 - 7.4e-28 97.6 0.1 7.8e-25 87.7 0.0 3.3 3 0 0 3 3 3 2 NUC173 domain Adaptin_N PF01602.20 GAX16220.1 - 1.8e-08 33.4 4.6 1.1e-07 30.8 0.7 2.3 2 0 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 GAX16220.1 - 4e-05 23.5 0.7 1.3 9.5 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat DUF4042 PF13251.6 GAX16220.1 - 0.00018 21.3 3.8 0.0071 16.1 0.5 3.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4042) Cnd1 PF12717.7 GAX16220.1 - 0.0013 18.8 3.9 0.91 9.6 0.3 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF3314 PF11771.8 GAX16220.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) ACT_6 PF13740.6 GAX16221.1 - 1.1e-13 50.9 0.0 2.4e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 ACT domain Mpv17_PMP22 PF04117.12 GAX16221.1 - 1e-11 44.9 0.2 2.2e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family ACT_4 PF13291.6 GAX16221.1 - 5.3e-10 39.7 0.3 0.0011 19.5 0.0 2.8 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 GAX16221.1 - 6e-06 25.9 0.0 0.00015 21.5 0.0 2.5 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.6 GAX16221.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 ACT domain WHEP-TRS PF00458.20 GAX16221.1 - 0.076 13.2 0.3 8.1 6.7 0.1 2.5 2 0 0 2 2 2 0 WHEP-TRS domain UAA PF08449.11 GAX16222.1 - 3.2e-52 177.6 19.4 3.8e-52 177.4 19.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX16222.1 - 8.2e-08 32.5 26.8 4.5e-05 23.6 10.0 2.8 3 0 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 GAX16222.1 - 1.1e-07 31.2 5.3 1.1e-07 31.2 5.3 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 GAX16222.1 - 8.9e-05 22.0 15.4 0.00016 21.1 15.4 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family Pex24p PF06398.11 GAX16222.1 - 0.043 12.8 0.8 0.062 12.3 0.8 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TMEM234 PF10639.9 GAX16222.1 - 2.6 8.1 11.5 0.062 13.3 1.0 2.7 2 1 0 2 2 2 0 Putative transmembrane family 234 Acetyltransf_1 PF00583.25 GAX16223.1 - 2.8e-18 66.2 0.0 3.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX16223.1 - 1.2e-09 38.2 0.1 2.1e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX16223.1 - 2.3e-09 37.6 0.0 3.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX16223.1 - 7.5e-08 32.2 0.1 1.2e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAX16223.1 - 0.001 19.2 0.1 0.0016 18.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAX16223.1 - 0.0041 16.9 0.2 0.0063 16.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_8 PF13523.6 GAX16223.1 - 0.0054 16.4 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX16223.1 - 0.0091 16.1 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 GAX16223.1 - 0.065 13.4 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UCH PF00443.29 GAX16224.1 - 1.2e-38 133.2 0.2 2.5e-38 132.0 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX16224.1 - 1.5e-16 60.9 2.3 4.6e-14 52.7 2.3 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Carb_anhydrase PF00194.21 GAX16225.1 - 5.5e-14 52.3 0.3 1.1e-09 38.2 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase eIF-5a PF01287.20 GAX16227.1 - 4.5e-09 36.3 0.1 8.4e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Trypsin_2 PF13365.6 GAX16228.1 - 1.1e-33 117.3 1.6 1.9e-33 116.5 1.6 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 GAX16228.1 - 8.1e-12 44.8 0.0 2.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 GAX16228.1 - 6.7e-11 42.4 0.1 1.5e-10 41.3 0.1 1.5 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 GAX16228.1 - 6.9e-10 39.1 0.0 2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX16228.1 - 4.2e-07 30.2 0.0 1.4e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 GAX16228.1 - 0.012 14.3 0.4 0.27 9.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase S46 Tricorn_PDZ PF14685.6 GAX16228.1 - 0.03 14.3 0.3 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_C4 PF00863.19 GAX16228.1 - 0.047 13.0 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C4 Trypsin_2 PF13365.6 GAX16229.1 - 1.7e-29 103.6 0.7 2.7e-29 103.0 0.7 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX16229.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 GAX16229.1 - 4.4e-07 29.6 0.1 1.2e-06 28.3 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX16229.1 - 1.6e-06 28.3 0.0 4.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX16229.1 - 4.3e-06 27.0 0.2 2e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 GAX16229.1 - 0.26 9.9 0.1 9.8 4.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 Trypsin_2 PF13365.6 GAX16230.1 - 1.9e-31 110.0 0.4 2.8e-31 109.4 0.4 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 GAX16230.1 - 3.2e-16 59.4 0.0 4.4e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX16230.1 - 1.6e-10 40.7 0.0 5.5e-10 38.9 0.0 2.0 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 GAX16230.1 - 2.5e-09 37.3 0.1 4e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ PF00595.24 GAX16230.1 - 2e-05 24.8 0.0 8e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 GAX16230.1 - 0.0073 15.0 0.0 0.3 9.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase S46 S1_2 PF13509.6 GAX16230.1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 S1 domain Thr_dehydrat_C PF00585.18 GAX16230.1 - 0.18 11.6 0.0 8.4 6.3 0.0 2.5 2 0 0 2 2 2 0 C-terminal regulatory domain of Threonine dehydratase Trypsin_2 PF13365.6 GAX16231.1 - 5.5e-32 111.7 3.2 9.8e-32 110.9 3.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 GAX16231.1 - 6.2e-12 45.7 0.0 1.7e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 GAX16231.1 - 4.5e-11 43.0 0.1 8.7e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 GAX16231.1 - 9e-08 31.8 0.1 2.3e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX16231.1 - 0.00014 22.1 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 GAX16231.1 - 0.032 12.9 0.1 0.77 8.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 LSM PF01423.22 GAX16231.1 - 0.13 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 LSM domain HMG_box PF00505.19 GAX16232.1 - 9.2e-05 22.8 9.6 0.022 15.1 0.4 3.2 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX16232.1 - 0.00071 20.1 8.4 0.0058 17.2 0.5 2.7 3 0 0 3 3 3 2 HMG-box domain DUF4770 PF15994.5 GAX16232.1 - 0.048 13.9 0.8 0.081 13.2 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FancD2 PF14631.6 GAX16232.1 - 0.25 8.7 0.9 0.32 8.4 0.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease LCIB_C_CA PF18599.1 GAX16233.1 - 2e-73 246.4 0.0 2.9e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF2680 PF10925.8 GAX16233.1 - 0.23 11.5 0.7 1 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) SNO PF01174.19 GAX16234.1 - 7.4e-40 136.8 0.0 7.9e-32 110.6 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase PF00117.28 GAX16234.1 - 6.1e-05 22.9 0.1 0.00025 20.9 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GAX16234.1 - 7.1e-05 22.5 0.2 0.00016 21.4 0.2 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain UPF0180 PF03698.13 GAX16234.1 - 0.08 13.1 0.4 28 5.0 0.2 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0180) DnaJ PF00226.31 GAX16235.1 - 2e-23 82.3 1.8 2.9e-23 81.7 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 GAX16235.1 - 6.9e-16 57.0 12.8 0.0004 20.3 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16235.1 - 1.9e-13 49.6 8.2 4.3e-07 29.5 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX16235.1 - 2.3e-07 31.0 15.5 0.00014 22.1 2.3 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX16235.1 - 4.7e-07 30.3 7.4 0.00099 19.7 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16235.1 - 4.8e-05 23.2 12.5 0.074 13.3 0.4 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX16235.1 - 0.0013 19.2 3.8 0.0024 18.4 0.1 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX16235.1 - 0.0014 18.7 4.6 0.17 12.1 0.6 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX16235.1 - 0.0016 18.7 4.5 0.007 16.6 1.8 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAX16235.1 - 0.0042 17.0 12.2 0.12 12.5 0.1 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 GAX16235.1 - 0.0045 17.1 0.6 0.044 13.8 0.3 2.6 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 GAX16235.1 - 0.019 15.3 0.3 4 8.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX16235.1 - 0.037 14.7 11.2 0.08 13.6 1.3 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX16235.1 - 0.063 12.7 2.2 0.23 10.9 0.0 3.0 4 0 0 4 4 4 0 SHNi-TPR SRP_TPR_like PF17004.5 GAX16235.1 - 0.19 11.7 1.5 2.2 8.4 0.3 2.7 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_10 PF13374.6 GAX16235.1 - 0.89 9.5 5.1 71 3.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16235.1 - 1.1 9.0 8.5 58 3.5 0.2 5.3 6 0 0 6 6 6 0 TPR repeat Aldedh PF00171.22 GAX16236.1 - 7.4e-137 456.6 0.2 8.9e-137 456.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAX16236.1 - 0.0029 17.1 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) PPI_Ypi1 PF07491.11 GAX16237.1 - 1.7e-20 72.6 0.0 3.4e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor PBP1_TM PF14812.6 GAX16237.1 - 0.19 12.1 2.2 0.29 11.5 2.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal bZIP_1 PF00170.21 GAX16238.1 - 0.0065 16.5 11.6 0.013 15.6 10.8 1.9 1 1 1 2 2 2 1 bZIP transcription factor SAB PF04382.13 GAX16238.1 - 0.018 15.1 1.4 0.042 13.9 1.4 1.6 1 0 0 1 1 1 0 SAB domain bZIP_2 PF07716.15 GAX16238.1 - 0.26 11.4 13.9 0.54 10.4 13.6 1.7 1 1 0 1 1 1 0 Basic region leucine zipper Glyco_transf_92 PF01697.27 GAX16239.1 - 2.2e-17 63.6 0.1 7.8e-17 61.8 0.1 2.0 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GAX16239.1 - 5.6e-08 33.2 0.0 1.5e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 EAP30 PF04157.16 GAX16240.1 - 1e-55 188.6 0.2 1.2e-55 188.4 0.2 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Sulfate_transp PF00916.20 GAX16241.1 - 2.7e-114 381.9 16.1 3.4e-114 381.5 16.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAX16241.1 - 9.7e-26 89.7 0.0 2e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAX16241.1 - 3.9e-05 23.9 0.0 7.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAX16241.1 - 0.0023 18.3 1.6 0.0023 18.3 1.6 3.5 2 1 1 3 3 3 1 Molybdate transporter of MFS superfamily DUF4010 PF13194.6 GAX16241.1 - 0.0069 16.1 6.0 0.0069 16.1 6.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4010) SLATT_5 PF18160.1 GAX16241.1 - 0.25 10.6 1.3 0.46 9.8 0.3 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3507 PF12015.8 GAX16242.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) PLDc_N PF13396.6 GAX16242.1 - 0.033 14.1 2.0 0.042 13.8 0.4 2.0 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal UBA PF00627.31 GAX16242.1 - 0.077 12.9 0.2 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 UBA/TS-N domain Peptidase_C14 PF00656.22 GAX16243.1 - 3.2e-42 145.2 3.2 3.2e-32 112.5 0.5 2.0 2 0 0 2 2 2 2 Caspase domain ABC_tran PF00005.27 GAX16244.1 - 2.4e-34 118.8 0.0 4.2e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX16244.1 - 6.9e-27 94.8 3.1 9.3e-27 94.4 3.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAX16244.1 - 1.6e-06 27.7 0.0 0.017 14.6 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX16244.1 - 5.2e-05 23.2 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX16244.1 - 9.8e-05 22.8 0.1 0.00041 20.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX16244.1 - 0.012 15.9 0.0 0.059 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAX16244.1 - 0.025 14.7 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX16244.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 GAX16244.1 - 0.041 13.6 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 GAX16244.1 - 0.056 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 GAX16244.1 - 0.13 12.4 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Ploopntkinase3 PF18751.1 GAX16244.1 - 0.16 11.9 0.0 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 GAX16244.1 - 1.5 9.3 3.9 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDZ_6 PF17820.1 GAX16245.1 - 0.00043 20.1 2.0 0.0017 18.1 2.0 2.0 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX16245.1 - 0.011 16.1 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 GAX16245.1 - 0.034 14.5 0.1 0.11 12.8 0.1 1.9 1 1 0 1 1 1 0 PDZ domain Glyco_transf_92 PF01697.27 GAX16246.1 - 6.8e-19 68.5 0.0 1.7e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GAX16246.1 - 1.5e-05 25.4 0.0 9.7e-05 22.8 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Peptidase_M41 PF01434.18 GAX16247.1 - 5.2e-62 209.1 0.1 8.4e-62 208.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAX16247.1 - 6.2e-44 149.6 0.0 1.4e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX16247.1 - 1.3e-11 44.1 0.0 3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 GAX16247.1 - 0.00014 21.2 0.1 0.00026 20.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GAX16247.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX16247.1 - 0.0049 17.3 0.2 0.14 12.5 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GAX16247.1 - 0.0053 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX16247.1 - 0.013 15.4 1.6 0.03 14.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsH_ext PF06480.15 GAX16247.1 - 0.014 15.7 0.0 0.048 14.0 0.0 1.9 2 0 0 2 2 2 0 FtsH Extracellular AAA_22 PF13401.6 GAX16247.1 - 0.015 15.6 0.7 0.14 12.4 0.1 2.5 2 1 1 3 3 2 0 AAA domain AAA_33 PF13671.6 GAX16247.1 - 0.035 14.3 0.0 0.08 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAX16247.1 - 0.038 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 GAX16247.1 - 0.058 13.8 0.3 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAX16247.1 - 0.1 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAX16247.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX16247.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAX16247.1 - 0.19 11.8 0.0 0.47 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SET PF00856.28 GAX16248.1 - 3.5e-06 27.5 0.2 0.00013 22.5 0.2 2.1 1 1 0 1 1 1 1 SET domain Fas_alpha_ACP PF18325.1 GAX16248.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.4 1 1 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain Pkinase PF00069.25 GAX16249.1 - 2.3e-64 217.3 0.0 3.4e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16249.1 - 5.9e-32 111.0 0.0 8.3e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX16249.1 - 0.0075 16.2 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX16249.1 - 0.042 12.8 0.0 0.34 9.8 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GAX16249.1 - 0.055 12.2 0.0 0.12 11.2 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 GAX16249.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 GAX16249.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PA PF02225.22 GAX16250.1 - 1.4e-07 31.4 0.3 3.1e-07 30.3 0.3 1.6 1 0 0 1 1 1 1 PA domain 2OG-FeII_Oxy_3 PF13640.6 GAX16250.1 - 0.00044 21.1 0.0 0.0021 18.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF4184 PF13803.6 GAX16250.1 - 0.11 12.2 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) Aminotran_3 PF00202.21 GAX16251.1 - 8e-75 252.0 0.0 1e-74 251.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAX16251.1 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAX16251.1 - 0.051 12.8 0.0 0.21 10.7 0.0 1.8 1 1 0 1 1 1 0 Aminotransferase class I and II SCO1-SenC PF02630.14 GAX16252.1 - 5e-43 146.2 0.0 6.7e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 GAX16252.1 - 2.2e-05 24.7 0.0 5.8e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 GAX16252.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX16252.1 - 0.0085 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin TPT PF03151.16 GAX16253.1 - 1e-15 57.9 12.9 1.2e-15 57.6 12.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX16253.1 - 1.5e-11 44.7 31.8 3.9e-08 33.6 16.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX16253.1 - 5.1e-09 35.8 9.8 7.9e-09 35.2 9.8 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 GAX16253.1 - 8.9e-06 25.1 14.4 1.2e-05 24.7 14.4 1.1 1 0 0 1 1 1 1 UAA transporter family DUF2070 PF09843.9 GAX16253.1 - 1.2 7.3 15.5 0.11 10.8 8.8 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) TctB PF07331.11 GAX16253.1 - 8.7 6.6 19.7 16 5.7 0.7 3.7 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family MMS19_N PF14500.6 GAX16254.1 - 3.9e-24 85.7 0.0 1.5e-23 83.7 0.0 2.1 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Sulfotransfer_2 PF03567.14 GAX16255.1 - 1.6e-05 25.0 0.6 5.1e-05 23.3 0.2 1.9 2 0 0 2 2 2 1 Sulfotransferase family Guanylate_cyc PF00211.20 GAX16256.1 - 3.8e-15 56.0 0.2 2.8e-07 30.3 0.0 2.9 2 1 1 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 GAX16256.1 - 3.1e-10 40.7 0.0 9.2e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF4948 PF16306.5 GAX16256.1 - 0.025 14.4 0.3 0.089 12.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4948) AAA_19 PF13245.6 GAX16256.1 - 0.08 13.3 0.0 0.3 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 GAX16258.1 - 2.1e-15 57.9 0.2 3.1e-15 57.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX16258.1 - 4.4e-11 42.9 2.7 2.1e-09 37.4 2.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX16258.1 - 2.4e-07 30.3 0.7 3.1e-07 29.9 0.3 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAX16258.1 - 4.1e-05 23.4 0.4 0.06 13.1 0.4 2.3 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAX16258.1 - 0.01 15.4 0.1 0.1 12.1 0.0 2.4 1 1 1 2 2 2 0 Putative serine esterase (DUF676) Esterase PF00756.20 GAX16258.1 - 0.013 15.2 0.0 0.041 13.5 0.0 1.8 2 0 0 2 2 2 0 Putative esterase DUF915 PF06028.11 GAX16258.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 GAX16258.1 - 0.017 15.2 0.2 0.029 14.5 0.2 1.4 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 GAX16258.1 - 0.029 14.2 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GAX16258.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1057 PF06342.12 GAX16258.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Ribosomal_S13_N PF08069.12 GAX16259.1 - 1.5e-29 101.8 0.1 2.9e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 GAX16259.1 - 6e-16 58.4 1.1 9.5e-16 57.8 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S4e PF00900.20 GAX16260.1 - 3.5e-32 110.1 2.1 8.7e-32 108.9 0.8 2.1 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 GAX16260.1 - 7.6e-24 83.1 0.4 2e-23 81.8 0.1 1.9 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 GAX16260.1 - 9e-09 34.9 0.4 6.7e-08 32.1 0.0 2.5 2 1 1 3 3 3 1 S4 domain RS4NT PF08071.12 GAX16260.1 - 1.1e-05 25.4 0.2 3.6e-05 23.8 0.2 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain KOW PF00467.29 GAX16260.1 - 0.00019 21.3 0.5 0.00019 21.3 0.5 2.5 2 0 0 2 2 2 1 KOW motif MOZ_SAS PF01853.18 GAX16261.1 - 3.7e-78 261.3 0.5 5.3e-78 260.8 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 GAX16261.1 - 9.5e-15 54.2 0.4 2.8e-14 52.7 0.4 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 GAX16261.1 - 8.5e-14 50.9 0.1 2.7e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 GAX16261.1 - 0.0074 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX16261.1 - 0.03 14.6 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family UL73_N PF12522.8 GAX16261.1 - 0.58 10.0 4.0 1.2 8.9 4.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Lipase_3 PF01764.25 GAX16262.1 - 2e-17 63.3 0.0 5.7e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 GAX16262.1 - 1.2e-11 44.6 8.5 3.2e-11 43.2 8.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-CRD PF17979.1 GAX16262.1 - 0.0029 17.7 2.0 0.0068 16.5 2.0 1.6 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions GidB PF02527.15 GAX16264.1 - 9.4e-30 103.3 0.0 1.5e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 GAX16264.1 - 8.6e-08 32.1 0.0 2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX16264.1 - 0.0011 19.7 0.0 0.0046 17.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX16264.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 GAX16264.1 - 0.065 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_23 PF13489.6 GAX16264.1 - 0.12 12.2 0.0 0.42 10.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Presenilin PF01080.17 GAX16264.1 - 5 5.8 6.9 0.16 10.7 0.8 1.5 2 0 0 2 2 2 0 Presenilin Spermine_synth PF01564.17 GAX16265.1 - 5.5e-39 133.5 0.0 1e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GAX16265.1 - 3.6e-12 46.0 0.3 8.7e-11 41.5 0.0 3.0 2 1 1 3 3 3 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAX16265.1 - 0.0019 18.8 0.0 0.0041 17.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX16265.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX16265.1 - 0.03 14.1 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 GAX16265.1 - 0.076 13.8 0.0 0.17 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.8 GAX16265.1 - 0.17 11.7 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MgtE PF01769.16 GAX16266.1 - 2.4e-18 66.7 10.7 7.4e-18 65.1 10.3 1.9 2 0 0 2 2 2 1 Divalent cation transporter HR1 PF02185.16 GAX16266.1 - 0.029 14.5 0.2 0.045 13.9 0.2 1.3 1 0 0 1 1 1 0 Hr1 repeat CCDC74_C PF14917.6 GAX16266.1 - 0.031 14.8 0.0 0.048 14.2 0.0 1.2 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal MPS2 PF17060.5 GAX16266.1 - 0.039 13.2 0.5 0.076 12.3 0.0 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 COMP PF11598.8 GAX16266.1 - 0.04 14.4 0.5 0.077 13.5 0.5 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein DUF305 PF03713.13 GAX16266.1 - 0.21 11.7 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Bap31_Bap29_C PF18035.1 GAX16266.1 - 0.22 11.6 1.2 0.34 11.0 1.2 1.2 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain PKcGMP_CC PF16808.5 GAX16266.1 - 0.25 11.3 2.1 0.45 10.4 2.1 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TFIIA PF03153.13 GAX16267.1 - 0.0036 17.4 8.8 0.31 11.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Podoplanin PF05808.11 GAX16267.1 - 0.036 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Podoplanin DUF998 PF06197.13 GAX16267.1 - 0.61 9.6 2.3 1.9 8.1 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF998) EF_TS PF00889.19 GAX16268.1 - 1.1e-40 139.5 0.8 1.5e-40 139.0 0.8 1.2 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.31 GAX16268.1 - 0.0024 17.7 0.0 0.0071 16.2 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain DNA_ligase_A_C PF04679.15 GAX16268.1 - 0.029 15.0 0.1 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region Sugar_tr PF00083.24 GAX16269.1 - 5e-22 78.4 9.0 1.5e-21 76.8 9.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX16269.1 - 1.9e-21 76.4 20.6 1.9e-21 76.4 20.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HSF_DNA-bind PF00447.17 GAX16270.1 - 7e-23 81.1 0.0 1.4e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_L7Ae PF01248.26 GAX16271.1 - 2.3e-20 72.1 2.6 2.8e-20 71.9 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Arrestin_C PF02752.22 GAX16272.1 - 0.037 14.5 0.4 0.17 12.3 0.2 2.2 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Ran_BP1 PF00638.18 GAX16274.1 - 8.7e-17 61.5 0.0 1.2e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 RanBP1 domain Pro_isomerase PF00160.21 GAX16275.1 - 4.4e-43 147.3 0.0 6.1e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RIBIOP_C PF04950.12 GAX16276.1 - 1.9e-100 336.1 0.0 3.4e-100 335.3 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAX16276.1 - 2.9e-08 33.7 0.0 7.9e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Popeye PF04831.13 GAX16277.1 - 3.5e-10 40.2 0.0 4.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 GAX16277.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Imp-YgjV PF10688.9 GAX16277.1 - 0.081 12.7 0.6 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 Bacterial inner membrane protein OAM_dimer PF16554.5 GAX16277.1 - 0.12 12.9 0.1 0.29 11.6 0.1 1.6 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase TPR_14 PF13428.6 GAX16278.1 - 4.4e-10 39.5 1.5 0.24 12.3 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX16278.1 - 5.7e-09 36.5 0.4 0.32 11.7 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16278.1 - 3.3e-08 33.0 9.3 0.077 13.1 0.0 6.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16278.1 - 1.5e-06 27.9 0.1 0.9 9.9 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX16278.1 - 4.8e-06 27.0 2.2 2.6 8.6 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX16278.1 - 2.1e-05 24.7 4.4 0.0052 17.0 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAX16278.1 - 0.0062 17.0 0.9 21 6.1 0.3 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16278.1 - 0.015 15.1 1.3 1.2 9.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX16278.1 - 0.062 13.5 0.2 5.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAX16278.1 - 0.11 12.9 0.2 62 4.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat AP3D1 PF06375.11 GAX16278.1 - 0.12 12.6 2.5 0.2 11.9 2.5 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TPR_10 PF13374.6 GAX16278.1 - 0.22 11.4 0.8 34 4.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Apocytochr_F_N PF16639.5 GAX16279.1 - 0.037 14.3 0.9 0.059 13.6 0.1 1.8 2 0 0 2 2 2 0 Apocytochrome F, N-terminal Peptidase_M8 PF01457.16 GAX16280.1 - 4.5e-53 180.7 6.1 6.7e-53 180.2 4.3 2.0 1 1 1 2 2 2 1 Leishmanolysin Peptidase_M10 PF00413.24 GAX16280.1 - 0.2 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin 2OG-FeII_Oxy_3 PF13640.6 GAX16281.1 - 0.016 16.1 0.0 0.022 15.6 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DnaJ PF00226.31 GAX16282.1 - 1.4e-13 50.8 0.0 6.4e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain TP53IP5 PF15331.6 GAX16282.1 - 0.0024 18.0 0.9 0.0037 17.5 0.9 1.2 1 0 0 1 1 1 1 Cellular tumour antigen p53-inducible 5 CDC45 PF02724.14 GAX16282.1 - 0.15 10.3 7.5 0.16 10.3 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GAX16282.1 - 0.23 10.2 0.6 0.3 9.8 0.6 1.3 1 0 0 1 1 1 0 Presenilin YlzJ PF14035.6 GAX16282.1 - 3 8.1 4.5 5.7 7.2 3.4 2.0 2 0 0 2 2 2 0 YlzJ-like protein MDM10 PF12519.8 GAX16282.1 - 3.4 6.4 9.6 5.3 5.8 9.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5428 PF17493.2 GAX16282.1 - 4 7.9 6.7 0.63 10.5 1.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5428) O-antigen_lig PF13425.6 GAX16282.1 - 5.7 5.6 9.1 0.53 9.0 1.8 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein MRP-S26 PF14943.6 GAX16282.1 - 7.3 6.5 21.6 2.7 7.9 18.7 1.7 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 AAA_22 PF13401.6 GAX16283.1 - 2.2e-10 40.9 0.0 9.9e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAX16283.1 - 4.3e-08 33.7 0.0 1.2e-07 32.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAX16283.1 - 2.1e-05 24.0 0.0 4.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein NB-ARC PF00931.22 GAX16283.1 - 0.022 14.0 0.1 0.26 10.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 GAX16283.1 - 0.048 14.0 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAX16283.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_lid_10 PF17872.1 GAX16283.1 - 0.11 12.7 0.5 0.3 11.2 0.5 1.7 1 0 0 1 1 1 0 AAA lid domain XRCC1_N PF01834.16 GAX16284.1 - 0.044 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain Ydc2-catalyt PF09159.10 GAX16285.1 - 0.0075 16.0 0.1 0.018 14.8 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 CBM9_2 PF16011.5 GAX16285.1 - 0.11 12.2 0.6 0.18 11.5 0.6 1.4 1 0 0 1 1 1 0 Carbohydrate-binding family 9 ERG4_ERG24 PF01222.17 GAX16286.1 - 9.2e-135 449.7 9.9 1.3e-134 449.3 9.9 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Hist_deacetyl PF00850.19 GAX16287.1 - 3.5e-51 174.5 0.3 6e-51 173.7 0.3 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Phlebovirus_NSM PF07246.11 GAX16288.1 - 0.025 14.0 2.0 0.03 13.7 2.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M V_ATPase_I PF01496.19 GAX16288.1 - 0.065 11.2 2.6 0.076 10.9 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PNGaseA PF12222.8 GAX16288.1 - 0.08 11.8 0.9 0.086 11.7 0.9 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Peptidase_S49_N PF08496.10 GAX16288.1 - 0.18 11.9 3.7 0.25 11.4 3.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PET117 PF15786.5 GAX16288.1 - 1.1 9.5 8.8 3 8.2 8.8 1.8 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Ferlin_C PF16165.5 GAX16288.1 - 5.1 7.0 8.4 8.2 6.4 8.4 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF1764 PF08576.10 GAX16288.1 - 8.6 7.3 10.5 13 6.8 10.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) NINJA_B PF16136.5 GAX16289.1 - 1.7 9.0 4.9 5 7.5 4.9 1.7 1 0 0 1 1 1 0 Putative nuclear localisation signal Band_7 PF01145.25 GAX16290.1 - 1e-29 103.8 0.4 2.2e-29 102.7 0.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 GAX16290.1 - 1e-16 60.7 0.5 2e-16 59.8 0.5 1.5 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 GAX16290.1 - 0.087 12.5 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 SPFH domain-Band 7 family TLD PF07534.16 GAX16291.1 - 3.6e-12 46.7 0.0 8e-12 45.6 0.0 1.7 1 1 0 1 1 1 1 TLD MFS_1 PF07690.16 GAX16292.1 - 6.3e-30 104.3 25.1 3.4e-29 101.9 25.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 GAX16292.1 - 0.00035 19.1 5.6 0.0007 18.1 5.6 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2770 PF10968.8 GAX16292.1 - 0.88 9.6 2.9 3.1 7.8 2.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) Ribul_P_3_epim PF00834.19 GAX16293.1 - 5.1e-87 290.4 0.3 6.1e-87 290.1 0.3 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 GAX16293.1 - 4e-07 30.0 0.0 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 GAX16293.1 - 0.0027 17.2 0.1 0.0065 16.0 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 GAX16293.1 - 0.054 12.7 0.1 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 GAX16293.1 - 0.072 12.4 0.4 0.63 9.3 0.1 2.3 2 1 0 2 2 2 0 Thiamine monophosphate synthase Glyoxalase_6 PF18029.1 GAX16293.1 - 0.13 13.1 0.1 12 6.7 0.0 2.3 1 1 1 2 2 2 0 Glyoxalase-like domain Got1 PF04178.12 GAX16294.1 - 5.2e-28 97.7 16.9 8.5e-28 97.0 16.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family WD40 PF00400.32 GAX16295.1 - 1.4e-16 60.5 13.8 0.001 19.9 0.9 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX16295.1 - 0.00011 22.4 0.0 1.8 8.9 0.0 4.2 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAP PF08373.10 GAX16296.1 - 7.9e-13 48.3 0.0 1.8e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 GAX16296.1 - 0.025 14.7 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 REase_MTES_1575 FAST_1 PF06743.15 GAX16296.1 - 0.058 13.3 0.0 0.39 10.7 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 DUF559 PF04480.12 GAX16296.1 - 0.14 12.0 0.0 0.99 9.3 0.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF559) DUF2358 PF10184.9 GAX16297.1 - 2.1e-08 34.4 0.0 3.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 GAX16297.1 - 0.0018 18.9 0.0 0.0032 18.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 GAX16297.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase NIF PF03031.18 GAX16298.1 - 4e-15 55.9 0.0 6.1e-14 52.1 0.1 2.3 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 GAX16298.1 - 4e-06 27.1 0.0 9.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAX16298.1 - 0.00072 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 GAX16298.1 - 0.028 14.7 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 GAX16298.1 - 0.035 14.5 0.0 0.45 11.0 0.0 2.6 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DUF4685 PF15737.5 GAX16298.1 - 0.68 10.4 4.4 0.25 11.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) SPR1 PF15356.6 GAX16299.1 - 0.06 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 Na_Ca_ex PF01699.24 GAX16301.1 - 4.5e-50 169.5 40.6 7.3e-26 90.9 20.3 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EF-hand_7 PF13499.6 GAX16301.1 - 6.5e-19 68.1 7.9 4.7e-12 46.2 1.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX16301.1 - 1.7e-16 58.7 7.0 0.00019 21.1 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 GAX16301.1 - 7.5e-15 53.3 8.9 0.0002 20.7 0.7 4.1 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 GAX16301.1 - 2.7e-14 51.9 5.3 0.00048 19.5 0.1 3.7 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 GAX16301.1 - 3.9e-08 33.6 1.6 0.0017 18.7 0.1 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 GAX16301.1 - 1.2e-06 28.2 0.3 0.0019 18.0 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair GH-E PF14410.6 GAX16301.1 - 0.25 11.8 0.7 3.2 8.2 0.0 2.3 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Chorismate_bind PF00425.18 GAX16302.1 - 2.6e-62 210.7 0.0 4.5e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 GAX16302.1 - 1.6e-39 135.7 0.0 3e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAX16302.1 - 6.6e-11 42.6 0.0 1.2e-08 35.3 0.0 3.3 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAX16302.1 - 1.3e-09 38.1 0.0 3.1e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 SAP PF02037.27 GAX16302.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 SAP domain MIP PF00230.20 GAX16303.1 - 1.2e-58 198.5 15.0 1.5e-58 198.2 15.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein RRM_1 PF00076.22 GAX16304.1 - 5.3e-24 83.8 0.1 9.6e-24 83.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 GAX16304.1 - 6.6e-11 41.6 9.1 1.4e-10 40.5 9.1 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 GAX16304.1 - 5.8e-06 26.7 0.3 5.8e-06 26.7 0.3 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.6 GAX16304.1 - 0.0011 18.5 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ThiP_synth PF10120.9 GAX16304.1 - 0.0058 16.3 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine-phosphate synthase DUF1866 PF08952.11 GAX16304.1 - 0.013 15.3 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 GAX16304.1 - 0.023 14.5 0.0 0.15 11.9 0.0 2.1 1 1 1 2 2 2 0 Occluded RNA-recognition motif OHCU_decarbox PF09349.10 GAX16304.1 - 0.042 14.3 1.8 0.051 14.1 0.2 1.9 2 0 0 2 2 2 0 OHCU decarboxylase SelR PF01641.18 GAX16305.1 - 0.00083 19.4 0.2 0.0024 17.9 0.2 1.9 1 1 0 1 1 1 1 SelR domain Pkinase PF00069.25 GAX16306.1 - 5e-59 199.8 0.0 1e-58 198.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX16306.1 - 3e-45 152.2 0.2 3.8e-17 62.1 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX16306.1 - 4.3e-36 124.5 0.0 2.9e-35 121.8 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Cupin_2 PF07883.11 GAX16306.1 - 0.00024 20.8 1.1 1.1 9.0 0.0 3.5 3 0 0 3 3 3 2 Cupin domain APH PF01636.23 GAX16306.1 - 0.00072 19.6 0.0 0.0023 17.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Polysacc_deac_1 PF01522.21 GAX16307.1 - 2.6e-09 37.0 0.0 6.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase CBM_14 PF01607.24 GAX16307.1 - 2.3e-07 30.8 2.6 2.3e-07 30.8 2.6 2.9 2 1 1 3 3 3 1 Chitin binding Peritrophin-A domain RT_RNaseH_2 PF17919.1 GAX16309.1 - 3.9e-31 107.0 0.1 1.3e-30 105.3 0.0 1.9 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAX16309.1 - 8.9e-28 96.6 0.1 1.6e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GAX16309.1 - 1.6e-13 50.9 0.0 3.5e-12 46.5 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.27 GAX16309.1 - 1.7e-13 50.6 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GAX16309.1 - 4.1e-10 39.6 0.0 9.8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GAX16309.1 - 0.01 15.6 0.0 0.049 13.4 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain LPD22 PF18834.1 GAX16309.1 - 0.033 14.4 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 gag_pre-integrs PF13976.6 GAX16309.1 - 0.079 12.8 0.3 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Ribosomal_S25 PF03297.15 GAX16310.1 - 4.9e-37 126.2 1.0 5.4e-37 126.0 1.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein GntR PF00392.21 GAX16310.1 - 0.031 13.9 0.2 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 GAX16310.1 - 0.058 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HSF_DNA-bind PF00447.17 GAX16311.1 - 9.5e-23 80.6 0.0 2.7e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding ENTH PF01417.20 GAX16312.1 - 0.0013 18.8 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 ENTH domain TFIIA PF03153.13 GAX16312.1 - 2.4 8.1 11.0 0.61 10.0 6.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HA PF03457.14 GAX16314.1 - 1.2e-38 131.2 2.4 3.8e-19 68.8 0.4 2.4 2 0 0 2 2 2 2 Helicase associated domain Glyoxalase_2 PF12681.7 GAX16314.1 - 0.096 12.6 0.1 1.6 8.7 0.0 2.4 1 1 1 2 2 2 0 Glyoxalase-like domain FA_desaturase PF00487.24 GAX16316.1 - 9.1e-39 133.8 13.6 9.1e-39 133.8 13.6 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAX16316.1 - 6.7e-07 29.4 0.4 1.7e-06 28.1 0.4 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Polysacc_deac_1 PF01522.21 GAX16317.1 - 4.8e-07 29.7 1.0 0.00093 19.1 0.0 3.4 2 1 0 2 2 2 2 Polysaccharide deacetylase CXCXC PF03128.14 GAX16317.1 - 0.82 10.3 12.8 4.9 7.8 1.1 3.1 2 0 0 2 2 2 0 CXCXC repeat RSN1_7TM PF02714.15 GAX16318.1 - 1.1e-23 83.9 15.6 2.5e-23 82.8 15.6 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX16318.1 - 1.7e-09 37.6 8.1 3e-08 33.6 0.2 3.4 4 0 0 4 4 4 2 Late exocytosis, associated with Golgi transport Polysacc_deac_1 PF01522.21 GAX16319.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF3228 PF11539.8 GAX16320.1 - 0.0061 16.1 0.1 2.8 7.4 0.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3228) HTH_Crp_2 PF13545.6 GAX16320.1 - 0.013 15.4 0.0 80 3.3 0.0 3.9 4 0 0 4 4 4 0 Crp-like helix-turn-helix domain MurB_C PF02873.16 GAX16320.1 - 0.15 12.1 0.0 27 4.8 0.0 3.2 2 1 1 3 3 3 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DUF1145 PF06611.12 GAX16321.1 - 0.033 14.1 0.2 0.033 14.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) Glyco_transf_49 PF13896.6 GAX16323.1 - 1.9e-35 122.8 0.0 7.4e-33 114.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAX16323.1 - 0.034 14.0 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAX16323.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_49 PF13896.6 GAX16324.1 - 3.3e-39 135.1 0.1 8.9e-37 127.2 0.1 2.1 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAX16324.1 - 0.021 14.6 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAX16324.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Proteasome PF00227.26 GAX16325.1 - 7e-11 42.0 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Cyt-b5 PF00173.28 GAX16326.1 - 2.6e-10 40.3 0.1 4.1e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2121 PF09894.9 GAX16326.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) TPR_12 PF13424.6 GAX16327.1 - 4.4e-60 199.9 17.7 1.3e-13 51.0 0.0 8.9 6 2 4 10 10 10 8 Tetratricopeptide repeat TPR_10 PF13374.6 GAX16327.1 - 1.7e-39 132.6 27.5 2.4e-05 24.0 0.0 12.5 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16327.1 - 1.9e-24 83.8 15.9 0.0029 17.6 0.2 10.3 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16327.1 - 8.4e-24 82.4 8.8 0.00068 19.4 0.1 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16327.1 - 3.9e-19 67.2 5.6 0.002 18.2 0.0 9.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX16327.1 - 1.1e-10 40.7 19.4 0.19 11.8 0.1 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX16327.1 - 1.4e-09 37.8 22.6 0.00056 19.4 1.3 4.4 3 1 1 4 4 4 4 MalT-like TPR region TPR_19 PF14559.6 GAX16327.1 - 1.8e-08 34.8 12.5 2.7 8.6 0.0 6.8 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAX16327.1 - 1.2e-06 29.1 19.9 0.32 11.7 0.1 7.0 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX16327.1 - 1.4e-05 25.4 9.4 23 5.9 0.1 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX16327.1 - 0.00029 21.0 6.8 63 4.3 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GAX16327.1 - 0.0027 17.2 3.1 0.9 8.9 0.0 3.6 4 0 0 4 4 4 2 Coatomer epsilon subunit TPR_9 PF13371.6 GAX16327.1 - 0.078 13.1 12.5 0.39 10.9 0.2 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat FRB_dom PF08771.11 GAX16327.1 - 0.16 12.4 0.5 1.5 9.3 0.3 2.7 1 1 0 2 2 2 0 FKBP12-rapamycin binding domain TPR_4 PF07721.14 GAX16327.1 - 1.5 9.6 9.3 24 5.9 0.1 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16327.1 - 6.2 6.6 15.7 2.4 7.9 0.1 6.9 7 2 1 8 8 8 0 TPR repeat HEAT PF02985.22 GAX16328.1 - 2.4e-32 108.2 21.4 0.0015 18.6 0.0 17.1 18 0 0 18 18 16 8 HEAT repeat HEAT_EZ PF13513.6 GAX16328.1 - 5.2e-32 109.9 28.1 0.0015 19.0 0.1 18.9 18 4 3 21 21 20 6 HEAT-like repeat HEAT_2 PF13646.6 GAX16328.1 - 1.7e-25 89.2 41.4 1e-05 25.8 0.0 16.3 14 3 3 18 18 18 8 HEAT repeats Cnd1 PF12717.7 GAX16328.1 - 7.4e-22 78.1 0.9 0.002 18.2 0.0 11.2 7 2 3 11 11 10 5 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAX16328.1 - 1.6e-12 46.8 2.2 3.2e-05 22.7 0.4 7.0 5 2 0 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 GAX16328.1 - 4e-12 46.6 0.0 0.13 12.9 0.0 8.1 8 1 2 10 10 10 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAX16328.1 - 5e-11 42.6 0.1 0.00021 21.0 0.0 7.4 6 1 1 7 7 7 2 CLASP N terminal UME PF08064.13 GAX16328.1 - 1.2e-08 34.8 0.8 1.3 9.0 0.0 7.5 6 1 1 8 8 7 2 UME (NUC010) domain ParcG PF10274.9 GAX16328.1 - 2e-08 34.5 1.3 0.91 9.6 0.0 7.5 9 1 1 10 10 10 2 Parkin co-regulated protein TIP120 PF08623.10 GAX16328.1 - 1.3e-05 25.0 2.6 0.012 15.4 0.0 4.7 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) Arm PF00514.23 GAX16328.1 - 3.1e-05 23.8 11.6 8.2 6.6 0.0 10.6 12 0 0 12 12 11 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 GAX16328.1 - 0.0032 17.3 0.1 2.2 8.3 0.1 5.5 6 0 0 6 6 6 1 Domain of unknown function (DUF3437) ADSL_C PF10397.9 GAX16328.1 - 0.065 13.8 0.6 2.9 8.5 0.0 3.9 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus DUF3385 PF11865.8 GAX16328.1 - 0.073 13.0 2.1 14 5.5 0.0 5.6 6 1 0 6 6 6 0 Domain of unknown function (DUF3385) SpoU_methylase PF00588.19 GAX16329.1 - 1.5e-28 99.8 0.0 2.9e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAX16329.1 - 0.0052 17.0 0.1 0.037 14.3 0.0 2.5 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding BrkDBD PF09607.10 GAX16329.1 - 0.16 11.8 0.5 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Brinker DNA-binding domain Strep_SA_rep PF06696.11 GAX16329.1 - 0.17 12.0 0.2 0.17 12.0 0.2 1.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat V-SNARE_C PF12352.8 GAX16330.1 - 2.8e-13 49.9 5.0 6.5e-13 48.8 5.0 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 GAX16330.1 - 5.2e-08 33.2 12.0 1.5e-07 31.6 6.9 3.0 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 GAX16330.1 - 3.2e-05 23.8 4.2 7.4e-05 22.6 0.0 2.9 1 1 1 3 3 3 1 Sec20 Nucleos_tra2_N PF01773.20 GAX16330.1 - 0.036 14.6 1.6 0.064 13.9 1.6 1.4 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus DUF573 PF04504.14 GAX16330.1 - 0.17 12.6 1.9 0.26 12.0 1.2 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Synaptobrevin PF00957.21 GAX16330.1 - 0.96 9.3 4.8 0.23 11.3 0.9 2.0 2 1 0 2 2 2 0 Synaptobrevin COG5 PF10392.9 GAX16330.1 - 0.97 9.6 6.6 0.2 11.8 0.4 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF2564 PF10819.8 GAX16330.1 - 1.3 9.5 7.4 1.2 9.5 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) FadA PF09403.10 GAX16330.1 - 5.2 7.6 12.2 3.3 8.2 1.1 3.4 3 1 1 4 4 4 0 Adhesion protein FadA V-ATPase_G_2 PF16999.5 GAX16330.1 - 5.6 7.4 9.5 5.7 7.4 1.0 2.5 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 GAX16330.1 - 6.9 6.0 11.9 17 4.7 11.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) RRM_1 PF00076.22 GAX16331.1 - 3.1e-18 65.3 0.0 5.4e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 GAX16331.1 - 7.4e-12 45.8 2.6 1.3e-11 45.0 2.6 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_occluded PF16842.5 GAX16331.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif U-box PF04564.15 GAX16332.1 - 6.9e-18 64.6 0.6 1.9e-17 63.2 0.1 1.8 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 GAX16332.1 - 0.00031 20.5 0.1 0.0018 18.1 0.0 2.1 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit T3SS_NleG PF06416.12 GAX16332.1 - 0.00081 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Effector protein NleG zf-rbx1 PF12678.7 GAX16332.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX16332.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX16332.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L13e PF01294.18 GAX16333.1 - 3.1e-53 180.3 2.3 5.2e-53 179.6 2.3 1.3 1 1 0 1 1 1 1 Ribosomal protein L13e PH PF00169.29 GAX16336.1 - 6.3e-09 36.3 0.0 1.5e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 GAX16336.1 - 1.7e-06 28.4 0.0 5.8e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain tRNA_bind PF01588.20 GAX16337.1 - 7.8e-24 83.6 0.0 1.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain AAA_lid_9 PF17871.1 GAX16337.1 - 0.19 11.7 0.6 0.32 11.0 0.6 1.3 1 0 0 1 1 1 0 AAA lid domain RRM_1 PF00076.22 GAX16338.1 - 2.7e-16 59.2 0.0 4.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX16338.1 - 3.9e-07 29.7 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LapA_dom PF06305.11 GAX16338.1 - 0.0039 17.0 0.1 0.0059 16.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain 2Fe-2S_thioredx PF01257.19 GAX16339.1 - 5.1e-06 26.4 0.1 7.3e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin FUSC PF04632.12 GAX16341.1 - 0.0025 16.4 2.1 0.004 15.8 2.1 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family DMPK_coil PF08826.10 GAX16341.1 - 0.1 12.7 6.6 0.97 9.6 6.6 2.7 1 1 0 1 1 1 0 DMPK coiled coil domain like Cep57_MT_bd PF06657.13 GAX16341.1 - 0.43 11.1 10.9 0.22 12.0 3.2 3.5 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2935 PF11155.8 GAX16341.1 - 2.1 8.7 6.1 0.55 10.6 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) LZ3wCH PF18517.1 GAX16341.1 - 3.7 7.7 6.2 0.96 9.6 0.8 2.6 2 0 0 2 2 2 0 Leucine zipper with capping helix domain HMG_box PF00505.19 GAX16342.1 - 1e-17 64.3 0.5 2.2e-17 63.2 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX16342.1 - 3.7e-15 56.3 1.2 8.6e-15 55.1 1.2 1.7 1 0 0 1 1 1 1 HMG-box domain CBFD_NFYB_HMF PF00808.23 GAX16342.1 - 2e-10 40.8 0.1 5.4e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX16342.1 - 3.7e-05 24.1 0.2 3.7e-05 24.1 0.2 2.9 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAX16342.1 - 0.14 12.3 0.2 0.29 11.4 0.2 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) NUP50 PF08911.11 GAX16343.1 - 3.2e-09 37.3 0.9 3.2e-09 37.3 0.9 4.7 2 1 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) But2 PF09792.9 GAX16343.1 - 1.5 9.2 10.3 0.65 10.4 5.1 2.6 1 1 1 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain RRM_1 PF00076.22 GAX16345.1 - 7.9e-18 64.1 0.0 9.9e-18 63.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX16345.1 - 7.3e-05 22.4 0.0 8.7e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAX16345.1 - 0.0041 17.1 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif BRAP2 PF07576.12 GAX16345.1 - 0.066 13.4 0.0 0.098 12.9 0.0 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 RL PF17797.1 GAX16345.1 - 0.09 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 RL domain RNA_bind PF08675.11 GAX16345.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 RNA binding domain DUF4294 PF14127.6 GAX16347.1 - 0.083 12.8 0.1 4.6 7.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) AMPK1_CBM PF16561.5 GAX16348.1 - 5.6e-34 116.2 0.3 1.1e-33 115.3 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 GAX16348.1 - 3.3e-25 88.1 5.0 5.8e-25 87.4 5.0 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 GAX16348.1 - 0.13 12.7 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) ABC_tran PF00005.27 GAX16349.1 - 4.6e-46 156.7 0.2 8.5e-22 78.1 0.0 4.1 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 GAX16349.1 - 1e-13 51.2 1.8 4.3e-05 23.1 0.0 4.3 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX16349.1 - 2.8e-13 50.3 0.0 0.006 16.4 0.0 4.4 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAX16349.1 - 1.1e-05 25.5 0.3 0.13 12.4 0.0 3.8 4 0 0 4 4 3 2 50S ribosome-binding GTPase 4HB PF17947.1 GAX16349.1 - 1.8e-05 24.7 1.4 5.3e-05 23.2 0.2 2.4 2 0 0 2 2 2 1 Four helical bundle domain AAA_22 PF13401.6 GAX16349.1 - 0.00018 21.8 0.0 0.35 11.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 GAX16349.1 - 0.00025 21.2 0.0 0.22 11.8 0.0 4.2 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAX16349.1 - 0.00026 20.7 0.1 0.13 12.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX16349.1 - 0.00029 20.8 0.1 0.016 15.1 0.0 2.8 2 1 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 GAX16349.1 - 0.0003 21.1 0.0 0.034 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain HEAT_EZ PF13513.6 GAX16349.1 - 0.00075 20.0 6.5 0.015 15.8 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat CLP1_P PF16575.5 GAX16349.1 - 0.00095 19.0 0.0 0.093 12.5 0.0 2.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA PF00004.29 GAX16349.1 - 0.0012 19.3 0.0 0.45 10.9 0.0 3.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 GAX16349.1 - 0.0014 18.4 0.0 0.55 10.0 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 GAX16349.1 - 0.0015 19.1 13.9 0.64 10.5 0.9 4.1 4 1 0 4 4 3 2 AAA domain DUF87 PF01935.17 GAX16349.1 - 0.0041 17.2 3.3 0.25 11.4 0.0 4.5 4 1 0 4 4 4 1 Helicase HerA, central domain DR2241 PF18069.1 GAX16349.1 - 0.0065 16.3 0.1 2.2 8.2 0.0 3.1 3 0 0 3 3 2 1 DR2241 stabilising domain Roc PF08477.13 GAX16349.1 - 0.011 16.0 0.0 5.6 7.2 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 GAX16349.1 - 0.011 15.4 10.8 0.62 9.7 0.0 3.9 4 1 0 4 4 3 0 AAA ATPase domain RNA_helicase PF00910.22 GAX16349.1 - 0.013 15.9 0.0 6 7.3 0.0 3.0 3 0 0 3 3 2 0 RNA helicase G-alpha PF00503.20 GAX16349.1 - 0.019 14.2 0.7 1.3 8.1 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit AAA_14 PF13173.6 GAX16349.1 - 0.042 13.9 0.0 1.2 9.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX16349.1 - 0.06 13.7 0.1 2.3 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 GAX16349.1 - 0.067 13.1 0.0 6.5 6.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Vac14_Fab1_bd PF12755.7 GAX16349.1 - 0.072 13.7 0.0 2.7 8.6 0.0 2.9 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAX16349.1 - 0.093 13.0 1.4 3.3 8.2 0.0 4.3 6 0 0 6 6 3 0 HEAT repeat ATP-synt_ab PF00006.25 GAX16349.1 - 0.1 12.3 0.0 0.77 9.4 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 GAX16349.1 - 0.62 10.1 3.1 0.82 9.7 0.0 2.8 3 0 0 3 3 2 0 Dynamin family FeoB_N PF02421.18 GAX16349.1 - 0.63 9.6 3.0 8.3 5.9 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF2786 PF10979.8 GAX16349.1 - 1 9.3 4.6 0.39 10.7 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) DnaJ PF00226.31 GAX16350.1 - 1e-22 80.0 0.5 1.7e-22 79.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain ShK PF01549.24 GAX16350.1 - 6.6e-09 36.2 5.0 1.1e-08 35.4 5.0 1.4 1 0 0 1 1 1 1 ShK domain-like VHL PF01847.16 GAX16350.1 - 0.052 13.5 0.7 0.49 10.3 0.8 2.2 1 1 1 2 2 2 0 VHL beta domain AAA_2 PF07724.14 GAX16351.1 - 6.7e-52 176.1 0.0 8.4e-49 166.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAX16351.1 - 5.2e-33 113.1 1.4 5.2e-33 113.1 1.4 2.9 2 1 1 3 3 2 1 AAA lid domain ClpB_D2-small PF10431.9 GAX16351.1 - 2.5e-22 78.7 0.5 1.1e-21 76.7 0.1 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GAX16351.1 - 6.4e-21 75.2 0.1 1.5e-11 44.9 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX16351.1 - 6.6e-16 58.6 1.0 2e-09 37.6 0.0 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX16351.1 - 6.1e-12 46.3 9.4 2.6e-05 24.7 0.1 5.2 4 1 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 GAX16351.1 - 1.5e-10 41.1 0.3 0.00015 21.5 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 GAX16351.1 - 7.6e-10 39.2 2.0 0.0045 17.3 0.0 4.8 3 1 1 4 4 4 2 AAA domain TniB PF05621.11 GAX16351.1 - 1.1e-07 31.5 0.1 0.00012 21.5 0.1 3.7 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 GAX16351.1 - 3.4e-07 29.9 0.0 0.017 14.6 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAX16351.1 - 7.5e-07 29.0 0.0 0.05 13.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAX16351.1 - 1.1e-06 28.2 1.3 0.025 14.0 0.1 3.7 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 GAX16351.1 - 2.1e-06 28.4 9.5 0.94 9.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 GAX16351.1 - 1.9e-05 23.9 0.2 0.0051 15.9 0.0 3.0 3 1 0 3 3 3 1 Type II/IV secretion system protein RuvB_N PF05496.12 GAX16351.1 - 4.8e-05 23.2 0.9 0.13 12.0 0.0 3.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 GAX16351.1 - 7.8e-05 22.7 0.0 0.065 13.1 0.1 3.8 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea TsaE PF02367.17 GAX16351.1 - 0.00022 21.2 0.1 0.82 9.7 0.0 3.6 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DivIC PF04977.15 GAX16351.1 - 0.00034 20.3 7.4 0.001 18.8 7.4 2.0 1 0 0 1 1 1 1 Septum formation initiator AAA_18 PF13238.6 GAX16351.1 - 0.00035 21.1 0.3 1.5 9.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain DNA_pol3_delta2 PF13177.6 GAX16351.1 - 0.00056 19.7 0.0 0.037 13.8 0.0 3.4 3 1 0 3 3 3 1 DNA polymerase III, delta subunit NACHT PF05729.12 GAX16351.1 - 0.00056 19.9 0.4 0.034 14.1 0.0 3.2 4 0 0 4 4 2 1 NACHT domain TIP49 PF06068.13 GAX16351.1 - 0.00068 18.9 2.3 0.28 10.3 0.0 2.9 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_28 PF13521.6 GAX16351.1 - 0.00077 19.7 3.6 0.22 11.8 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.6 GAX16351.1 - 0.00078 19.8 1.3 0.62 10.4 0.1 3.8 3 1 0 3 3 2 1 AAA domain PhoH PF02562.16 GAX16351.1 - 0.001 18.6 0.0 0.049 13.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_6 PF12774.7 GAX16351.1 - 0.0017 17.4 0.1 0.083 11.8 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 GAX16351.1 - 0.0021 18.4 0.0 2.8 8.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 GAX16351.1 - 0.0035 17.1 0.0 0.71 9.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 GAX16351.1 - 0.0043 17.1 2.5 1.3 9.0 0.0 3.3 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 GAX16351.1 - 0.011 14.9 0.1 0.75 8.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) SRP54 PF00448.22 GAX16351.1 - 0.016 14.8 0.3 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 GAX16351.1 - 0.016 14.9 0.0 6.2 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 GAX16351.1 - 0.018 15.3 0.0 7.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 GAX16351.1 - 0.027 14.6 0.7 12 6.1 0.0 3.4 3 0 0 3 3 2 0 AAA domain Torsin PF06309.11 GAX16351.1 - 0.03 14.4 0.0 0.98 9.5 0.0 2.4 2 0 0 2 2 2 0 Torsin ABC_tran PF00005.27 GAX16351.1 - 0.059 13.9 5.0 4.5 7.8 0.1 3.2 3 1 0 3 3 2 0 ABC transporter Parvo_NS1 PF01057.17 GAX16351.1 - 0.075 12.1 0.1 0.44 9.6 0.0 2.2 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 Snapin_Pallidin PF14712.6 GAX16351.1 - 0.33 11.4 10.5 0.16 12.4 6.5 2.7 2 1 0 2 2 1 0 Snapin/Pallidin UvrD-helicase PF00580.21 GAX16351.1 - 0.72 9.3 7.6 8.7 5.8 3.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Cauli_AT PF03233.13 GAX16351.1 - 0.98 9.3 3.1 2.8 7.9 3.1 1.8 1 0 0 1 1 1 0 Aphid transmission protein DUF87 PF01935.17 GAX16351.1 - 3 7.9 6.3 5.7 7.0 0.0 3.6 4 0 0 4 4 4 0 Helicase HerA, central domain CbiA PF01656.23 GAX16351.1 - 7.8 6.6 5.7 8.9 6.4 0.4 3.3 2 2 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Plasmid_RAQPRD PF09686.10 GAX16351.1 - 9 6.6 10.0 0.42 10.9 0.9 2.9 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) UQ_con PF00179.26 GAX16352.1 - 8.1e-46 155.2 0.0 9.1e-46 155.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX16352.1 - 0.022 14.5 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 GAX16352.1 - 0.088 13.1 0.2 0.11 12.8 0.2 1.5 1 1 0 1 1 1 0 RWD domain NIR_SIR PF01077.22 GAX16353.1 - 1.7e-52 177.1 0.1 2.5e-37 127.9 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 GAX16353.1 - 4.8e-39 132.0 0.0 9.9e-20 70.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Glu_cyclase_2 PF05096.12 GAX16354.1 - 2.5e-64 217.1 0.7 3e-64 216.9 0.7 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase DUF1082 PF06449.11 GAX16354.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Pkinase_Tyr PF07714.17 GAX16355.1 - 9e-34 116.9 0.0 1.6e-33 116.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX16355.1 - 1.9e-32 112.7 0.0 3.8e-32 111.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GAX16355.1 - 0.0019 17.6 0.0 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAX16355.1 - 0.0033 16.3 0.1 0.0066 15.3 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX16355.1 - 0.038 13.9 0.2 0.091 12.7 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Na_H_Exchanger PF00999.21 GAX16356.1 - 1e-38 133.1 28.6 1.3e-38 132.8 28.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 GAX16357.1 - 7.4e-39 133.6 29.3 1.1e-38 133.0 29.3 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Rad51 PF08423.11 GAX16358.1 - 3.5e-119 396.8 0.5 1.9e-118 394.3 0.1 2.0 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 GAX16358.1 - 6.4e-13 48.8 0.2 9.3e-13 48.2 0.2 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 GAX16358.1 - 1.5e-09 37.7 0.1 2.4e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAX16358.1 - 4e-07 29.6 1.1 1.3e-06 27.9 1.1 1.9 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 GAX16358.1 - 5.7e-05 23.6 0.2 0.00021 21.8 0.2 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 GAX16358.1 - 0.0011 18.7 0.1 0.026 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX16358.1 - 0.0047 17.2 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain HHH_2 PF12826.7 GAX16358.1 - 0.01 15.9 0.1 0.072 13.2 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif DnaB_C PF03796.15 GAX16358.1 - 0.028 13.8 0.2 0.5 9.6 0.1 2.3 1 1 0 2 2 2 0 DnaB-like helicase C terminal domain LPD22 PF18834.1 GAX16358.1 - 0.17 12.1 2.5 0.61 10.3 0.1 2.9 4 0 0 4 4 4 0 Large polyvalent protein associated domain 22 ILVD_EDD PF00920.21 GAX16359.1 - 3.9e-205 682.4 0.0 4.5e-205 682.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 GAX16359.1 - 0.013 15.7 0.1 11 6.4 0.0 3.2 3 0 0 3 3 3 0 FeoA domain PEP-utilizers PF00391.23 GAX16359.1 - 0.02 14.6 0.7 0.059 13.1 0.1 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain VIR_N PF15912.5 GAX16360.1 - 0.04 13.5 1.2 0.049 13.2 1.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 GAX16360.1 - 0.11 12.0 5.5 0.12 11.8 5.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 GAX16360.1 - 0.56 10.7 8.6 0.21 12.0 4.9 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein PRIMA1 PF16101.5 GAX16360.1 - 0.89 9.6 7.1 1.2 9.1 7.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 GAX16360.1 - 2.8 8.0 10.5 3.2 7.8 10.5 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator Ten1_2 PF15490.6 GAX16361.1 - 9.1e-08 31.8 0.2 5.5e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Telomere-capping, CST complex subunit PRA1 PF03208.19 GAX16363.1 - 2.6e-09 36.9 0.4 2.6e-09 36.9 0.4 1.7 2 0 0 2 2 2 1 PRA1 family protein PFL-like PF02901.15 GAX16364.1 - 8.3e-167 556.7 0.0 1.3e-166 556.1 0.0 1.2 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 GAX16364.1 - 6e-37 126.4 0.0 4.1e-36 123.7 0.0 2.5 3 0 0 3 3 3 1 Glycine radical Radical_SAM PF04055.21 GAX16364.1 - 1.6e-14 54.6 0.0 4e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAX16364.1 - 1.4e-11 44.8 0.2 3.3e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3029 PF11230.8 GAX16364.1 - 0.00025 19.6 0.0 0.00062 18.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3029) Fer4_14 PF13394.6 GAX16364.1 - 0.0023 18.1 0.2 0.007 16.5 0.2 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Amino_oxidase PF01593.24 GAX16365.1 - 8.7e-76 256.0 0.0 2.7e-75 254.4 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase zf-HC5HC2H PF13771.6 GAX16365.1 - 1.6e-15 57.1 35.0 9.4e-11 41.8 7.9 4.4 3 1 1 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAX16365.1 - 2.4e-14 53.4 30.1 8.3e-09 35.6 10.9 2.8 2 1 0 2 2 2 2 PHD-zinc-finger like domain NAD_binding_8 PF13450.6 GAX16365.1 - 9e-13 48.3 0.1 2.4e-12 46.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX16365.1 - 2.9e-05 23.8 0.1 5.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX16365.1 - 0.00012 22.1 1.1 0.00035 20.6 0.1 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAX16365.1 - 0.0032 16.7 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX16365.1 - 0.0056 17.2 0.6 0.028 15.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX16365.1 - 0.014 14.5 0.1 0.032 13.3 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAX16365.1 - 0.026 13.6 0.3 0.075 12.1 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Lipase_GDSL_2 PF13472.6 GAX16365.1 - 0.16 12.4 0.4 2.1 8.7 0.0 2.6 3 0 0 3 3 2 0 GDSL-like Lipase/Acylhydrolase family Thi4 PF01946.17 GAX16365.1 - 0.17 11.1 0.1 0.52 9.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family SEEEED PF14797.6 GAX16365.1 - 0.65 10.2 11.7 1.3 9.2 11.7 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex DUF1990 PF09348.10 GAX16367.1 - 7.5e-16 58.5 3.6 3.8e-10 40.0 0.5 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF1990) DUF3246 PF11596.8 GAX16367.1 - 0.05 13.0 0.5 0.075 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF2840 PF11000.8 GAX16367.1 - 0.16 11.8 1.2 0.37 10.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) IMUP PF15761.5 GAX16367.1 - 0.19 12.4 3.3 0.48 11.1 3.3 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein Dehydrin PF00257.19 GAX16367.1 - 0.93 10.0 3.9 1 9.9 2.5 1.7 2 0 0 2 2 2 0 Dehydrin IGPD PF00475.18 GAX16368.1 - 8.5e-64 214.2 0.9 3.8e-31 108.3 0.0 3.0 2 1 1 3 3 3 2 Imidazoleglycerol-phosphate dehydratase LCE6A PF15858.5 GAX16368.1 - 0.017 15.8 2.7 0.044 14.5 2.7 1.6 1 0 0 1 1 1 0 Late cornified envelope protein 6A family SUIM_assoc PF16619.5 GAX16368.1 - 0.063 13.4 1.1 0.16 12.1 1.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Isochorismatase PF00857.20 GAX16369.1 - 5.1e-22 78.9 0.1 6.7e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family PAP2 PF01569.21 GAX16370.1 - 2.7e-10 40.1 0.1 5.3e-09 35.9 0.2 2.7 2 1 0 2 2 2 1 PAP2 superfamily FAM176 PF14851.6 GAX16370.1 - 2 8.1 6.6 19 4.9 3.9 2.2 1 1 1 2 2 2 0 FAM176 family RAP1 PF07218.11 GAX16370.1 - 4.6 5.4 8.0 7.2 4.7 8.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LRR19-TM PF15176.6 GAX16371.1 - 0.11 12.5 0.5 0.22 11.5 0.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain zf-HIT PF04438.16 GAX16373.1 - 0.00037 20.3 11.6 0.00072 19.4 11.6 1.5 1 0 0 1 1 1 1 HIT zinc finger CAAX_1 PF15895.5 GAX16373.1 - 0.078 12.9 1.0 0.69 9.8 0.4 2.1 2 0 0 2 2 2 0 CAAX box cerebral protein 1 Myc_N PF01056.18 GAX16375.1 - 0.011 15.7 6.3 0.018 15.0 6.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF4637 PF15470.6 GAX16375.1 - 0.33 10.7 8.3 0.97 9.1 8.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Radial_spoke PF04712.12 GAX16375.1 - 0.44 9.4 9.1 0.7 8.8 9.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein F_bP_aldolase PF01116.20 GAX16376.1 - 7.6e-86 288.1 0.0 8.8e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Acetyltransf_2 PF00797.17 GAX16379.1 - 0.049 13.4 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 N-acetyltransferase PKD PF00801.20 GAX16382.1 - 0.19 11.6 0.2 12 5.8 0.0 2.6 2 0 0 2 2 2 0 PKD domain VWA PF00092.28 GAX16383.1 - 6.5e-13 49.3 0.6 1.1e-12 48.6 0.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAX16383.1 - 6.4e-11 42.8 0.7 1.9e-10 41.3 0.7 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX16383.1 - 3e-06 27.3 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GAX16383.1 - 0.0026 17.2 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein dCache_1 PF02743.18 GAX16383.1 - 0.019 14.7 0.1 0.065 13.0 0.0 1.9 2 1 0 2 2 2 0 Cache domain ArlS_N PF18719.1 GAX16387.1 - 0.074 13.3 0.0 4.5 7.5 0.0 2.8 3 0 0 3 3 3 0 ArlS sensor domain STAG PF08514.11 GAX16389.1 - 0.076 12.9 0.0 0.74 9.7 0.0 2.3 2 0 0 2 2 2 0 STAG domain Trypan_PARP PF05887.11 GAX16391.1 - 0.0038 17.2 10.5 0.0087 16.0 10.5 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) HyaE PF07449.11 GAX16392.1 - 0.088 12.8 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE ETM PF17577.2 GAX16392.1 - 0.16 12.5 0.5 0.43 11.2 0.2 1.8 1 1 1 2 2 2 0 ECORI-T site DUF469 PF04320.14 GAX16393.1 - 0.13 13.1 0.1 0.37 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein with unknown function (DUF469) DUF3695 PF12494.8 GAX16394.1 - 0.11 12.3 0.1 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) MORN PF02493.20 GAX16396.1 - 1.5e-29 100.1 40.6 1.4e-07 31.0 3.6 7.4 7 0 0 7 7 7 6 MORN repeat DUF35_N PF12172.8 GAX16396.1 - 0.02 14.8 0.7 0.02 14.8 0.7 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3048_C PF17479.2 GAX16396.1 - 0.064 13.6 1.3 0.086 13.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Ribosomal_L26 PF16906.5 GAX16401.1 - 1.3e-33 115.3 2.8 1.6e-33 115.0 2.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAX16401.1 - 0.00032 20.5 1.0 0.00074 19.4 1.0 1.7 1 0 0 1 1 1 1 KOW motif RRM_1 PF00076.22 GAX16402.1 - 2.7e-12 46.3 0.9 2.7e-07 30.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Astro_capsid_p PF12226.8 GAX16402.1 - 1.5 7.9 9.3 2.2 7.3 9.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 GAX16402.1 - 3.3 6.9 8.1 4.7 6.4 8.1 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GAX16402.1 - 5.2 6.1 13.6 9.4 5.3 13.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Spt5_N PF11942.8 GAX16402.1 - 8.1 7.5 16.5 9.3 7.3 12.2 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF285 PF03382.14 GAX16403.1 - 1.7e-117 386.1 57.7 2e-34 118.0 9.5 4.3 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 DUF1266 PF06889.11 GAX16403.1 - 0.01 15.9 1.3 1.8 8.6 0.0 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1266) CYYR1 PF10873.8 GAX16404.1 - 0.12 12.9 1.4 0.2 12.1 0.1 2.0 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF285 PF03382.14 GAX16405.1 - 3.8e-93 307.5 60.6 2.9e-37 127.1 19.5 3.2 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 DUF4939 PF16297.5 GAX16405.1 - 0.0024 17.7 3.3 0.67 9.8 0.7 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4939) DUF285 PF03382.14 GAX16406.1 - 2.9e-206 672.6 142.8 8e-34 116.0 13.7 6.0 1 1 6 7 7 7 7 Mycoplasma protein of unknown function, DUF285 NAF PF03822.14 GAX16406.1 - 3 8.1 16.4 4.6 7.5 0.4 6.6 6 3 0 6 6 6 0 NAF domain DUF285 PF03382.14 GAX16407.1 - 6.3e-113 371.4 74.4 1.8e-32 111.6 16.1 4.1 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 DUF285 PF03382.14 GAX16408.1 - 6.9e-297 965.2 238.6 1.6e-36 124.7 17.6 6.4 1 1 9 10 10 10 10 Mycoplasma protein of unknown function, DUF285 Phage_tail_L PF05100.12 GAX16408.1 - 5.3 6.3 10.9 2.9 7.2 0.1 3.8 2 1 2 5 5 5 0 Phage minor tail protein L DUF393 PF04134.12 GAX16409.1 - 5.6e-23 82.4 0.0 7.9e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 SNF2_N PF00176.23 GAX16412.1 - 6.2e-68 229.1 0.1 1e-67 228.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX16412.1 - 0.00011 22.5 0.0 0.00029 21.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 GAX16412.1 - 0.00015 22.0 3.2 0.00015 22.0 3.2 4.6 3 1 1 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 GAX16412.1 - 0.026 14.3 1.3 0.2 11.4 1.3 2.7 1 0 0 1 1 1 0 RING-like zinc finger PEMT PF04191.13 GAX16413.1 - 8.2e-15 55.1 0.2 1.4e-14 54.3 0.2 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 GAX16413.1 - 2.2e-07 31.2 0.0 4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NnrU PF07298.11 GAX16413.1 - 0.019 14.5 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 NnrU protein DUF1295 PF06966.12 GAX16413.1 - 0.043 13.3 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF3575 PF12099.8 GAX16413.1 - 0.13 11.5 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) TMEM215 PF15746.5 GAX16413.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 TMEM215 family P16-Arc PF04699.14 GAX16414.1 - 0.0096 16.4 7.8 0.019 15.4 7.8 1.4 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF4366 PF14283.6 GAX16414.1 - 0.065 13.3 6.6 1.5 8.8 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4366) Spt20 PF12090.8 GAX16414.1 - 0.16 11.5 12.8 0.3 10.6 12.8 1.4 1 0 0 1 1 1 0 Spt20 family PGAP1 PF07819.13 GAX16417.1 - 4.7e-39 134.5 0.1 7.3e-39 133.8 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAX16417.1 - 2.5e-05 25.0 0.1 5.9e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX16417.1 - 0.00015 21.5 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX16417.1 - 0.0034 16.7 0.0 0.0083 15.4 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 GAX16417.1 - 0.0038 16.9 0.0 0.0066 16.1 0.0 1.5 1 1 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 GAX16417.1 - 0.0044 16.6 1.3 0.029 13.9 0.1 2.4 3 0 0 3 3 3 1 Lipid-droplet associated hydrolase DUF676 PF05057.14 GAX16417.1 - 0.009 15.5 0.1 0.038 13.5 0.0 2.0 2 1 0 2 2 2 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 GAX16417.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 GAX16417.1 - 0.083 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TLP1_add_C PF18313.1 GAX16417.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Glyco_hydro_36 PF17167.4 GAX16417.1 - 0.092 11.4 0.0 0.2 10.3 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase 36 superfamily, catalytic domain Polysacc_syn_2C PF08485.10 GAX16417.1 - 0.13 11.9 0.8 0.27 11.0 0.8 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal Abhydrolase_8 PF06259.12 GAX16417.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Mito_carr PF00153.27 GAX16418.1 - 7.1e-46 154.1 5.4 5.8e-17 61.4 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Chorismate_bind PF00425.18 GAX16420.1 - 4.2e-53 180.6 0.0 7.8e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme TPP_enzyme_N PF02776.18 GAX16420.1 - 4.3e-33 114.4 0.6 9.1e-33 113.3 0.6 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Abhydrolase_1 PF00561.20 GAX16420.1 - 3.9e-10 39.8 0.1 8e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold MR_MLE_C PF13378.6 GAX16420.1 - 2.3e-08 33.9 1.9 1.6e-07 31.2 0.2 2.7 3 0 0 3 3 3 1 Enolase C-terminal domain-like Polyketide_cyc2 PF10604.9 GAX16420.1 - 3.1e-07 30.8 0.1 6.9e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX16420.1 - 0.046 13.9 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Fasciclin PF02469.22 GAX16423.1 - 1.2e-35 122.5 0.1 9.7e-21 74.3 0.1 2.4 2 0 0 2 2 2 2 Fasciclin domain MS_channel PF00924.18 GAX16427.1 - 2.5e-24 86.0 0.1 3.6e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel MS_channel PF00924.18 GAX16428.1 - 2.6e-26 92.5 0.0 3.4e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2854 PF11016.8 GAX16429.1 - 1.2e-45 155.0 0.0 1.5e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) Peptidase_M43 PF05572.13 GAX16430.1 - 1.5e-16 60.6 0.3 2.4e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 GAX16430.1 - 0.0005 19.8 3.2 0.0011 18.7 0.0 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX16430.1 - 0.0034 17.6 0.2 0.0089 16.2 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 GAX16430.1 - 0.013 15.3 0.2 0.021 14.7 0.2 1.4 1 1 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 GAX16430.1 - 0.022 15.2 0.0 0.054 14.0 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAX16430.1 - 0.029 13.3 0.6 0.052 12.5 0.6 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 GAX16430.1 - 0.042 13.7 0.4 0.09 12.7 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 GAX16430.1 - 0.053 12.7 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Pkinase PF00069.25 GAX16431.1 - 9.3e-35 120.3 0.0 1.3e-33 116.5 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16431.1 - 3.2e-30 105.3 0.0 4.7e-29 101.4 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX16431.1 - 3.5e-05 22.8 0.0 4.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 GAX16431.1 - 0.084 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 CemA PF03040.14 GAX16433.1 - 0.025 14.5 1.1 0.025 14.5 1.1 1.9 2 0 0 2 2 2 0 CemA family DUF4810 PF16068.5 GAX16434.1 - 0.23 12.0 1.3 10 6.7 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) HCMV_UL139 PF12507.8 GAX16434.1 - 3 8.2 8.5 15 5.9 1.4 2.7 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein RRP7 PF12923.7 GAX16435.1 - 3.5e-13 49.7 3.7 3.5e-13 49.7 3.7 2.1 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 GAX16435.1 - 1.9e-07 31.0 0.4 7.2e-07 29.1 0.0 2.2 2 1 1 3 3 3 1 Rrp7 RRM-like N-terminal domain RNA_pol_Rpb4 PF03874.16 GAX16435.1 - 0.018 15.4 1.5 0.018 15.4 1.5 2.9 2 1 0 2 2 2 0 RNA polymerase Rpb4 DUF5093 PF17011.5 GAX16435.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.3 3 2 2 5 5 5 0 Domain of unknown function (DUF5093) RRM_7 PF16367.5 GAX16435.1 - 0.44 10.7 1.9 13 6.0 0.3 3.3 3 1 1 4 4 4 0 RNA recognition motif Ima1_N PF09779.9 GAX16435.1 - 2.7 8.9 10.5 0.61 10.9 3.9 2.3 1 1 1 2 2 2 0 Ima1 N-terminal domain Rsc14 PF08586.10 GAX16435.1 - 3 8.7 6.2 3.3 8.6 0.9 2.5 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Pkinase PF00069.25 GAX16437.1 - 2.5e-27 95.9 0.0 1.7e-26 93.2 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16437.1 - 8e-25 87.6 0.0 3.8e-23 82.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX16437.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SET PF00856.28 GAX16439.1 - 7.8e-10 39.4 0.5 8e-05 23.1 0.0 4.0 4 1 0 4 4 4 2 SET domain SAF PF08666.12 GAX16439.1 - 0.11 13.1 0.0 40 4.9 0.0 3.3 3 0 0 3 3 3 0 SAF domain DnaJ-X PF14308.6 GAX16440.1 - 2.4e-32 112.1 0.1 2.4e-32 112.1 0.1 3.5 4 1 1 5 5 5 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAX16440.1 - 1.6e-22 79.4 2.9 6.5e-22 77.4 2.9 2.1 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 GAX16440.1 - 4.3e-07 30.2 0.2 2.4e-06 27.8 0.2 2.3 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF5320 PF17253.2 GAX16440.1 - 3.4 8.8 10.5 12 7.0 0.1 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5320) TPR_2 PF07719.17 GAX16441.1 - 6.6e-08 32.1 8.4 0.0032 17.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX16441.1 - 9.4e-07 28.4 0.7 0.00043 20.1 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16441.1 - 1.8e-06 27.5 9.1 0.0005 19.8 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GAX16441.1 - 0.00017 21.6 3.5 0.0006 19.8 1.9 2.7 2 0 0 2 2 2 1 Putative TPR-like repeat TPR_12 PF13424.6 GAX16441.1 - 0.00034 20.8 4.8 0.63 10.4 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16441.1 - 0.00076 19.5 6.3 0.042 14.1 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX16441.1 - 0.003 18.1 6.3 0.27 12.0 0.4 3.7 3 0 0 3 3 2 2 Tetratricopeptide repeat MIT PF04212.18 GAX16441.1 - 0.0035 17.4 2.0 2.4 8.3 0.0 3.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain DUF2383 PF09537.10 GAX16441.1 - 0.0045 17.3 3.6 7.9 6.9 0.0 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2383) ANAPC3 PF12895.7 GAX16441.1 - 0.005 17.0 9.9 0.18 12.0 4.7 4.1 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAX16441.1 - 0.0062 17.2 1.0 2.8 8.6 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SRP72 PF08492.12 GAX16441.1 - 0.0066 16.9 7.0 0.0066 16.9 7.0 2.7 2 1 0 2 2 1 1 SRP72 RNA-binding domain TPR_11 PF13414.6 GAX16441.1 - 0.0076 15.9 0.7 4.1 7.2 0.0 3.2 3 0 0 3 3 3 1 TPR repeat GyrI-like PF06445.15 GAX16441.1 - 0.081 13.2 0.1 0.6 10.4 0.0 2.4 2 0 0 2 2 2 0 GyrI-like small molecule binding domain TPR_14 PF13428.6 GAX16441.1 - 0.4 11.6 12.5 1.1 10.3 0.0 5.2 5 2 2 7 7 4 0 Tetratricopeptide repeat DUF1635 PF07795.11 GAX16441.1 - 0.63 9.9 11.6 0.039 13.8 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) TraT PF05818.12 GAX16443.1 - 0.13 12.0 0.6 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF4551 PF15087.6 GAX16443.1 - 0.16 10.7 0.2 0.2 10.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) AtpR PF12966.7 GAX16443.1 - 0.6 10.6 6.9 0.36 11.3 2.9 2.3 2 0 0 2 2 2 0 N-ATPase, AtpR subunit PrmA PF06325.13 GAX16444.1 - 1.7e-09 37.5 0.1 2.9e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX16444.1 - 7.4e-05 23.4 0.1 0.00039 21.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX16444.1 - 0.0007 19.4 0.0 0.0017 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX16444.1 - 0.0013 18.3 0.1 0.0023 17.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 GAX16444.1 - 0.0022 19.0 0.0 0.0055 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX16444.1 - 0.0029 17.6 0.2 0.0057 16.6 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX16444.1 - 0.003 18.1 0.0 0.01 16.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX16444.1 - 0.0031 17.4 0.0 0.0043 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX16444.1 - 0.0067 15.8 0.4 0.012 14.9 0.2 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 GAX16444.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 GAX16444.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 GAX16444.1 - 0.089 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 GAX16444.1 - 0.13 11.7 0.1 0.26 10.7 0.1 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB Coq4 PF05019.13 GAX16445.1 - 9e-66 221.4 0.0 1.1e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Pkinase PF00069.25 GAX16446.1 - 1.7e-32 112.8 0.0 1.8e-31 109.5 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16446.1 - 3e-29 102.1 0.0 1.4e-27 96.6 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase TPR_12 PF13424.6 GAX16447.1 - 3.2e-30 104.2 17.8 1.8e-12 47.3 0.0 6.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16447.1 - 3.2e-23 80.5 13.8 0.00012 21.7 0.1 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16447.1 - 8.8e-22 75.4 16.2 0.001 19.0 1.1 7.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAX16447.1 - 1.3e-16 59.3 14.9 0.061 13.4 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16447.1 - 6.6e-14 50.9 10.0 0.0013 18.8 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX16447.1 - 1.1e-12 47.3 15.5 0.014 15.2 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16447.1 - 9.7e-11 41.2 2.5 0.011 15.5 0.0 6.3 6 1 0 6 6 6 2 TPR repeat TPR_16 PF13432.6 GAX16447.1 - 6e-09 36.4 1.8 6.7e-05 23.5 0.3 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX16447.1 - 1.1e-07 31.6 2.1 0.00054 19.4 0.0 2.8 2 1 0 2 2 2 2 MalT-like TPR region TPR_6 PF13174.6 GAX16447.1 - 3.8e-06 27.2 8.0 9.8 7.1 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX16447.1 - 6.9e-06 26.5 13.3 3.2 8.8 0.2 7.3 6 2 2 8 8 8 1 Tetratricopeptide repeat SNAP PF14938.6 GAX16447.1 - 1.1e-05 25.1 4.4 0.044 13.2 0.0 4.1 3 2 1 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 GAX16447.1 - 5.4e-05 23.0 1.6 0.0058 16.4 0.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GAX16447.1 - 9.6e-05 22.5 6.5 0.53 10.5 0.7 5.2 4 2 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX16447.1 - 0.0041 16.5 0.2 1.9 8.0 0.0 3.8 3 0 0 3 3 3 1 SHNi-TPR TPR_17 PF13431.6 GAX16447.1 - 0.029 14.7 0.0 45 4.7 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat ApbE PF02424.15 GAX16447.1 - 0.045 13.3 0.0 0.26 10.8 0.0 2.1 1 1 1 2 2 2 0 ApbE family MIT PF04212.18 GAX16447.1 - 0.052 13.6 8.1 4.3 7.5 0.2 5.4 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 GAX16447.1 - 0.052 14.1 11.5 1.1 9.8 0.2 5.3 5 1 2 7 7 7 0 Tetratricopeptide repeat ComR_TPR PF18710.1 GAX16447.1 - 0.065 12.8 4.1 6.3 6.3 0.0 3.1 3 0 0 3 3 3 0 ComR tetratricopeptide RPN7 PF10602.9 GAX16447.1 - 0.071 12.8 10.2 4.6 6.9 0.0 4.2 2 1 2 4 4 4 0 26S proteasome subunit RPN7 Sel1 PF08238.12 GAX16447.1 - 0.2 12.4 4.0 34 5.3 0.0 4.4 5 1 0 5 5 4 0 Sel1 repeat ANAPC5 PF12862.7 GAX16447.1 - 0.26 11.4 4.0 2.8 8.1 0.4 3.0 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 5 PPR PF01535.20 GAX16447.1 - 0.37 11.2 7.3 47 4.5 0.0 6.2 8 0 0 8 8 7 0 PPR repeat T5orf172 PF10544.9 GAX16447.1 - 0.38 11.3 5.0 1.8 9.1 0.0 3.1 2 1 1 3 3 3 0 T5orf172 domain DUF5344 PF17279.2 GAX16447.1 - 0.5 11.0 3.0 3.2 8.4 0.0 3.5 4 1 0 4 4 2 0 Family of unknown function (DUF5344) E1-E2_ATPase PF00122.20 GAX16448.1 - 2.2e-47 160.9 7.2 1.7e-45 154.7 4.9 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX16448.1 - 1.8e-33 115.8 3.6 1.8e-33 115.8 3.6 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAX16448.1 - 2.4e-26 93.3 0.2 2e-20 74.0 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX16448.1 - 1.7e-16 59.7 0.1 1.7e-16 59.7 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAX16448.1 - 7.4e-16 58.0 0.0 3.5e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAX16448.1 - 0.00049 19.9 1.3 0.0024 17.7 1.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX16448.1 - 0.024 15.0 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 GAX16449.1 - 2e-50 171.7 44.1 1.1e-37 129.8 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX16449.1 - 1.9e-08 33.7 29.3 3.3e-07 29.5 5.7 3.8 1 1 2 4 4 4 3 Sugar (and other) transporter MFS_1_like PF12832.7 GAX16449.1 - 2.5e-07 29.9 11.0 0.00067 18.6 2.9 3.0 2 1 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 GAX16449.1 - 1.3e-06 27.1 28.5 0.00046 18.7 18.9 3.0 1 1 1 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 GAX16449.1 - 0.00014 20.8 7.9 0.0025 16.7 3.4 2.7 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_4 PF06779.14 GAX16449.1 - 0.11 11.7 30.4 14 4.8 30.4 2.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 GAX16449.1 - 1.9 6.7 16.5 0.14 10.4 3.1 3.4 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family COX14 PF14880.6 GAX16450.1 - 0.042 13.7 0.6 0.077 12.8 0.6 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF3306 PF11748.8 GAX16450.1 - 0.1 13.5 1.0 0.24 12.3 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Nucleolin_bd PF16725.5 GAX16450.1 - 0.12 12.1 0.2 0.31 10.7 0.2 1.7 1 0 0 1 1 1 0 Nucleolin binding domain Globin PF00042.22 GAX16451.1 - 9.8e-09 35.8 0.0 4.8e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Globin RuBisCO_small PF00101.20 GAX16451.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Sulfotransfer_3 PF13469.6 GAX16452.1 - 0.00059 20.3 1.0 0.066 13.6 1.0 2.6 1 1 0 1 1 1 1 Sulfotransferase family Clat_adaptor_s PF01217.20 GAX16453.1 - 1.1e-50 171.2 4.0 1.7e-50 170.6 4.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Guanylate_cyc PF00211.20 GAX16454.1 - 2e-47 161.2 0.0 3.5e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX16454.1 - 4.2e-27 95.4 0.4 9.9e-27 94.2 0.4 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDZ_6 PF17820.1 GAX16454.1 - 3.6e-06 26.7 0.0 9e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX16454.1 - 8.1e-06 26.1 0.1 2.3e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 PDZ domain GAF_2 PF13185.6 GAX16454.1 - 0.035 14.4 0.0 0.17 12.1 0.0 2.2 1 0 0 1 1 1 0 GAF domain TMEM126 PF07114.11 GAX16454.1 - 0.076 12.4 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 126 RuvC_1 PF18516.1 GAX16454.1 - 0.11 11.7 0.6 1.1 8.4 0.0 2.6 3 0 0 3 3 3 0 RuvC nuclease domain Arrestin_N PF00339.29 GAX16456.1 - 9e-06 25.8 0.0 0.0012 18.9 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAX16456.1 - 0.0071 16.8 0.0 0.11 12.9 0.0 2.6 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAX16457.1 - 1.5e-12 47.8 0.0 4.8e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF4476 PF14771.6 GAX16457.1 - 4.4e-11 42.9 0.1 9e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) Arrestin_C PF02752.22 GAX16457.1 - 9.7e-05 22.8 0.0 0.0023 18.4 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain C2 PF00168.30 GAX16457.1 - 0.00046 20.4 0.0 1.7 9.0 0.0 2.7 2 0 0 2 2 2 2 C2 domain Arrestin_C PF02752.22 GAX16458.1 - 5.2e-08 33.4 0.0 3.9e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAX16458.1 - 0.0039 17.3 0.3 0.16 12.0 0.0 3.0 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAX16458.1 - 0.0057 16.4 0.2 1.6 8.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin_N terminal like Gp_dh_C PF02800.20 GAX16459.1 - 5.4e-57 191.8 0.1 7.9e-57 191.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX16459.1 - 5.1e-32 110.2 0.0 1.3e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GET2 PF08690.10 GAX16460.1 - 0.056 13.1 3.6 0.1 12.2 3.6 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 CRR7 PF12095.8 GAX16460.1 - 0.17 12.4 0.7 0.33 11.4 0.7 1.4 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 adh_short PF00106.25 GAX16462.1 - 3.3e-34 118.1 0.6 7.1e-25 87.6 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX16462.1 - 1.8e-22 80.1 0.1 4.9e-16 59.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX16462.1 - 4.6e-07 29.9 0.1 1e-06 28.8 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAX16462.1 - 0.0027 17.2 0.0 0.0095 15.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF3976 PF13121.6 GAX16462.1 - 0.058 13.5 0.1 18 5.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3976) LEM PF03020.15 GAX16462.1 - 0.12 11.9 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 LEM domain Flagellin_N PF00669.20 GAX16462.1 - 0.24 11.5 0.8 3.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Glyco_trans_1_2 PF13524.6 GAX16463.1 - 3.7e-11 43.3 0.0 1.3e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Galactosyl_T PF01762.21 GAX16463.1 - 0.034 14.0 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 Galactosyltransferase Fringe PF02434.16 GAX16463.1 - 0.07 12.6 0.9 0.41 10.0 0.4 2.3 2 1 0 2 2 2 0 Fringe-like Glyco_trans_1_2 PF13524.6 GAX16464.1 - 1.2e-12 48.0 0.0 2.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 GAX16466.1 - 1.4e-32 113.1 0.0 3.5e-31 108.5 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16466.1 - 6.4e-29 101.0 0.0 1.3e-27 96.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase zf-CW PF07496.15 GAX16467.1 - 4.7e-29 100.1 26.5 1.7e-16 60.0 8.9 2.6 2 0 0 2 2 2 2 CW-type Zinc Finger Sporozoite_P67 PF05642.11 GAX16467.1 - 0.36 8.8 6.3 0.64 8.0 6.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PTPRCAP PF15713.5 GAX16467.1 - 0.73 10.1 12.3 0.056 13.7 6.9 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RRN3 PF05327.11 GAX16467.1 - 1.8 7.0 5.9 3 6.3 5.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 GAX16467.1 - 3.5 7.1 15.1 5.6 6.5 15.1 1.4 1 0 0 1 1 1 0 PPP4R2 Sarcoglycan_1 PF04790.13 GAX16468.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein DUF3103 PF11301.8 GAX16469.1 - 0.0082 15.0 0.5 0.016 14.0 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3103) NTP_transf_2 PF01909.23 GAX16469.1 - 0.055 13.8 0.0 0.25 11.7 0.0 2.1 3 0 0 3 3 3 0 Nucleotidyltransferase domain Pollen_allerg_1 PF01357.21 GAX16470.1 - 0.00045 20.2 0.1 0.0009 19.2 0.1 1.5 1 0 0 1 1 1 1 Pollen allergen Pollen_allerg_1 PF01357.21 GAX16471.1 - 0.041 13.9 0.1 0.08 13.0 0.1 1.5 1 0 0 1 1 1 0 Pollen allergen Pollen_allerg_1 PF01357.21 GAX16472.1 - 0.0057 16.7 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.17 GAX16472.1 - 0.0074 16.1 0.4 0.014 15.2 0.4 1.5 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 GAX16472.1 - 0.074 13.2 2.9 0.42 10.8 0.3 2.6 2 1 0 3 3 3 0 Cerato-platanin Isochorismatase PF00857.20 GAX16473.1 - 2.8e-18 66.7 0.0 5.2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Herpes_MCP PF03122.14 GAX16473.1 - 0.0042 14.6 0.1 0.0057 14.2 0.1 1.1 1 0 0 1 1 1 1 Herpes virus major capsid protein FA_desaturase PF00487.24 GAX16474.1 - 1.2e-27 97.4 29.7 1.2e-27 97.4 29.7 2.9 2 1 1 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAX16474.1 - 1.7e-11 44.1 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3792 PF12670.7 GAX16474.1 - 0.27 11.4 10.8 4.3 7.5 0.6 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3792) WD40 PF00400.32 GAX16476.1 - 5.1e-09 36.6 4.3 8.9e-05 23.2 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 GAX16476.1 - 0.019 14.0 0.0 0.054 12.5 0.0 1.7 1 1 1 2 2 2 0 Coatomer WD associated region ANAPC4_WD40 PF12894.7 GAX16476.1 - 0.021 15.1 0.1 12 6.2 0.0 4.1 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SRP9-21 PF05486.12 GAX16476.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Ank_2 PF12796.7 GAX16477.1 - 1.2e-05 25.8 0.0 0.15 12.7 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAX16477.1 - 2.6e-05 24.4 0.9 0.37 11.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 GAX16477.1 - 0.0016 19.0 0.1 2.7 8.7 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX16477.1 - 0.0049 17.3 3.5 0.44 11.3 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat Laminin_G_3 PF13385.6 GAX16477.1 - 0.1 12.7 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Elicitin PF00964.17 GAX16477.1 - 0.14 12.2 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Elicitin HSP70 PF00012.20 GAX16478.1 - 1.2e-77 261.5 16.3 1.9e-77 260.8 6.0 2.9 1 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 GAX16478.1 - 0.043 12.6 0.3 0.19 10.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein AbiEi_3_N PF17194.4 GAX16478.1 - 0.14 12.2 0.0 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain DUF563 PF04577.14 GAX16480.1 - 6.3e-20 72.2 0.7 1.1e-19 71.4 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Gln-synt_N PF03951.19 GAX16480.1 - 0.029 14.1 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain PfkB PF00294.24 GAX16483.1 - 3e-70 236.9 7.7 4.1e-70 236.5 7.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Glyco_hydro_16 PF00722.21 GAX16484.1 - 2.9e-08 33.4 0.0 6.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Flavi_NS2B PF01002.19 GAX16484.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Flavivirus non-structural protein NS2B O-FucT PF10250.9 GAX16485.1 - 1.1e-46 160.1 0.1 1.5e-46 159.6 0.1 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase eIF-3c_N PF05470.12 GAX16486.1 - 5.8e-139 464.1 32.3 2.1e-97 326.9 6.1 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 GAX16486.1 - 1.5e-10 41.5 0.0 4.2e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain FAS_N PF17828.1 GAX16486.1 - 0.015 15.3 1.1 0.5 10.4 0.6 2.6 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta SR-25 PF10500.9 GAX16486.1 - 0.38 10.3 48.8 0.48 10.0 7.7 3.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein LRR_8 PF13855.6 GAX16487.1 - 1.6e-24 85.4 24.8 2.4e-07 30.4 0.9 6.2 3 2 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GAX16487.1 - 5.3e-23 80.7 15.1 0.0013 19.1 0.0 7.0 3 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX16487.1 - 3.4e-08 32.9 16.1 3.3 8.6 0.0 10.6 13 1 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.6 GAX16487.1 - 0.017 15.1 20.1 36 4.8 0.0 8.5 10 0 0 10 10 10 0 Leucine Rich repeat GIT_CC PF16559.5 GAX16488.1 - 0.00024 20.9 2.3 0.00055 19.8 2.3 1.6 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Fungal_TACC PF12709.7 GAX16488.1 - 0.0043 17.5 0.9 0.0099 16.3 0.9 1.6 1 0 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins LRR_8 PF13855.6 GAX16488.1 - 0.0045 16.7 1.3 5.5 6.8 0.1 3.6 3 1 1 4 4 4 2 Leucine rich repeat GAS PF13851.6 GAX16488.1 - 0.0094 15.3 1.9 0.016 14.5 1.9 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ADIP PF11559.8 GAX16488.1 - 0.0096 16.0 3.8 0.023 14.8 3.8 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 GAX16488.1 - 0.019 15.1 1.6 0.037 14.1 1.6 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF2968 PF11180.8 GAX16488.1 - 0.03 14.0 1.4 0.051 13.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Cep57_CLD_2 PF14197.6 GAX16488.1 - 0.036 14.2 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF16 PF01519.16 GAX16488.1 - 0.057 13.9 2.0 0.13 12.8 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 APG6_N PF17675.1 GAX16488.1 - 0.066 13.8 1.9 0.13 12.8 1.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 GAX16488.1 - 0.067 12.5 2.3 0.14 11.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.12 GAX16488.1 - 0.089 13.4 1.4 0.26 11.9 1.1 2.0 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 GAX16488.1 - 0.15 11.9 1.2 0.38 10.6 1.2 1.6 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.19 GAX16488.1 - 0.23 9.3 1.0 0.36 8.7 1.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LRR_6 PF13516.6 GAX16488.1 - 0.24 11.5 3.3 66 3.9 0.0 4.9 6 0 0 6 6 4 0 Leucine Rich repeat TMF_DNA_bd PF12329.8 GAX16488.1 - 2.7 8.1 9.6 0.11 12.5 2.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF817 PF05675.12 GAX16490.1 - 0.02 14.6 1.6 0.036 13.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF817) Amastin PF07344.11 GAX16491.1 - 0.018 14.9 9.6 0.018 14.9 9.6 1.8 2 0 0 2 2 2 0 Amastin surface glycoprotein ECF_trnsprt PF12822.7 GAX16491.1 - 3 7.9 9.8 8 6.5 9.9 1.7 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DUF3675 PF12428.8 GAX16491.1 - 5.8 7.5 7.4 0.38 11.3 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Myb_DNA-binding PF00249.31 GAX16492.1 - 8.5e-09 35.5 0.0 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain IL2 PF00715.17 GAX16492.1 - 0.015 15.2 2.1 0.033 14.1 2.1 1.6 1 0 0 1 1 1 0 Interleukin 2 DUF948 PF06103.11 GAX16492.1 - 0.17 12.2 3.7 0.14 12.5 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AICARFT_IMPCHas PF01808.18 GAX16493.1 - 4.2e-83 279.2 2.1 5.3e-83 278.9 2.1 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 GAX16493.1 - 1.4e-24 86.0 0.0 2.8e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain zf-RING_2 PF13639.6 GAX16494.1 - 1.3e-10 41.4 11.2 2.6e-10 40.5 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX16494.1 - 1.2e-07 31.9 10.0 4.5e-07 30.0 10.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAX16494.1 - 4.4e-06 26.3 5.3 1.1e-05 25.1 5.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX16494.1 - 4.6e-05 23.2 9.8 4.6e-05 23.2 9.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX16494.1 - 8.4e-05 22.5 6.4 0.00021 21.3 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX16494.1 - 0.00015 21.6 8.3 0.00015 21.6 8.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX16494.1 - 0.00019 21.3 10.6 0.0003 20.6 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX16494.1 - 0.00041 19.9 6.0 0.00082 18.9 6.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAX16494.1 - 0.00046 20.1 8.9 0.001 19.0 8.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAX16494.1 - 0.0011 18.8 7.9 0.0023 17.8 7.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX16494.1 - 0.0023 18.0 6.1 0.0077 16.3 6.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAX16494.1 - 0.027 14.6 6.0 0.092 12.9 6.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 GAX16494.1 - 0.078 13.2 3.7 0.2 11.9 3.7 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_9 PF13901.6 GAX16494.1 - 0.13 12.2 5.8 0.29 11.1 5.8 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_6 PF14835.6 GAX16494.1 - 0.24 11.3 2.2 0.5 10.3 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RINGv PF12906.7 GAX16494.1 - 0.46 10.6 10.1 0.97 9.6 10.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 GAX16494.1 - 4.3 7.5 6.9 0.4 10.8 2.1 1.9 2 0 0 2 2 1 0 Zinc-finger zf-RING-like PF08746.11 GAX16494.1 - 5.2 7.5 9.6 10 6.6 9.6 1.5 1 0 0 1 1 1 0 RING-like domain Resolvase PF00239.21 GAX16496.1 - 0.0034 17.5 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain CxC6 PF18721.1 GAX16497.1 - 0.0016 18.7 18.5 0.15 12.3 3.2 3.6 1 1 2 3 3 3 3 CxC6 like cysteine cluster associated with KDZ transposases DUF2587 PF10759.9 GAX16497.1 - 0.044 13.3 0.2 0.52 9.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2587) Peptidase_C13 PF01650.18 GAX16499.1 - 7.6e-41 140.3 0.4 9.9e-41 139.9 0.4 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF924 PF06041.11 GAX16500.1 - 3e-36 125.2 0.0 3.5e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Abhydrolase_1 PF00561.20 GAX16503.1 - 5.1e-05 23.0 0.4 0.00021 21.0 0.2 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Endonuc-MspI PF09208.10 GAX16504.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease MspI DUF4134 PF13572.6 GAX16505.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) PRRSV_2b PF07069.11 GAX16506.1 - 0.061 13.8 0.3 2 9.0 0.0 2.7 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Pkinase PF00069.25 GAX16507.1 - 5.9e-28 98.0 0.0 7.2e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16507.1 - 2.7e-17 62.9 0.0 3.3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX16507.1 - 2.6e-09 36.3 0.1 3.6e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX16507.1 - 0.00068 19.6 0.0 0.005 16.8 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAX16507.1 - 0.12 11.4 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CBFD_NFYB_HMF PF00808.23 GAX16508.1 - 1.8e-20 73.0 0.3 1.8e-20 73.0 0.3 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX16508.1 - 2.9e-12 47.1 0.9 2.9e-12 47.1 0.9 2.6 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 GAX16508.1 - 0.0064 16.5 2.9 0.46 10.5 0.1 2.5 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit EnY2 PF10163.9 GAX16508.1 - 1.3 9.5 9.3 5.6 7.4 2.0 3.0 2 1 1 3 3 3 0 Transcription factor e(y)2 HTH_32 PF13565.6 GAX16508.1 - 7.3 7.3 7.3 13 6.5 0.1 3.0 2 1 1 3 3 3 0 Homeodomain-like domain Flavodoxin_1 PF00258.25 GAX16509.1 - 9.3e-21 74.5 0.0 5e-19 68.9 0.0 2.1 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 GAX16509.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_1 PF00258.25 GAX16510.1 - 1.6e-18 67.3 0.1 2e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin MctB PF11382.8 GAX16510.1 - 0.073 12.8 0.1 0.13 11.9 0.0 1.4 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB DUF547 PF04784.14 GAX16511.1 - 3.9e-09 36.6 0.1 8.3e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Gpr1_Fun34_YaaH PF01184.19 GAX16512.1 - 2.3e-07 30.6 13.7 3.6e-07 30.0 13.7 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SPC12 PF06645.13 GAX16512.1 - 0.034 14.2 3.9 2.6 8.2 0.2 2.8 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Gpr1_Fun34_YaaH PF01184.19 GAX16513.1 - 2.9e-12 46.6 10.3 4.9e-12 45.9 10.3 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Varsurf_PPLC PF03490.13 GAX16514.1 - 0.00046 20.1 0.0 0.0014 18.5 0.0 1.8 2 0 0 2 2 2 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.19 GAX16514.1 - 0.0026 17.3 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Sad1_UNC PF07738.13 GAX16514.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Fucose_iso_C PF02952.17 GAX16515.1 - 0.077 12.7 0.1 0.62 9.8 0.1 2.1 2 0 0 2 2 2 0 L-fucose isomerase, C-terminal domain HABP4_PAI-RBP1 PF04774.15 GAX16516.1 - 1.7e-13 51.4 7.4 1.7e-13 51.4 7.4 4.0 2 1 2 4 4 4 1 Hyaluronan / mRNA binding family Dicty_REP PF05086.12 GAX16516.1 - 0.94 7.4 2.3 1.2 7.0 2.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 GAX16516.1 - 4.9 5.2 5.8 6.5 4.8 5.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_1 PF00232.18 GAX16517.1 - 1.4e-156 521.4 5.1 5.3e-155 516.3 2.9 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 Glyco_hydro_18 PF00704.28 GAX16517.1 - 2.7e-10 40.5 0.4 1.3e-09 38.2 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Lipase_GDSL_2 PF13472.6 GAX16517.1 - 0.12 12.7 0.0 7.7 6.9 0.0 2.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MMR_HSR1_Xtn PF16897.5 GAX16518.1 - 6.8e-37 125.7 0.3 1.2e-36 125.0 0.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 GAX16518.1 - 1.4e-20 73.5 0.1 3.6e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX16518.1 - 1.1e-10 41.3 0.0 2.4e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 GAX16518.1 - 1.3e-09 38.0 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 GAX16518.1 - 0.00043 20.4 0.1 1.1 9.3 0.0 2.5 3 0 0 3 3 3 2 Dynamin family MeaB PF03308.16 GAX16518.1 - 0.013 14.5 0.2 0.023 13.7 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1192 PF06698.11 GAX16518.1 - 0.014 15.5 1.1 0.62 10.2 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) AIG1 PF04548.16 GAX16518.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Phage_GP20 PF06810.11 GAX16518.1 - 0.06 13.2 0.6 0.097 12.5 0.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 ABC_tran PF00005.27 GAX16518.1 - 0.08 13.5 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 GAX16518.1 - 0.096 12.6 1.6 7 6.5 0.0 2.8 4 0 0 4 4 4 0 RsgA GTPase Roc PF08477.13 GAX16518.1 - 0.1 12.9 0.1 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF4355 PF14265.6 GAX16518.1 - 0.49 10.6 2.6 7.2 6.9 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) GDC-P PF02347.16 GAX16520.1 - 5.4e-186 618.6 0.4 5.5e-175 582.3 0.0 3.0 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 GAX16520.1 - 6.4e-07 28.7 0.7 7.2e-06 25.2 0.1 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAX16520.1 - 8.3e-05 22.0 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 GAX16520.1 - 0.085 11.6 0.0 6.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 GAX16520.1 - 0.11 11.6 0.1 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II RNase_H2-Ydr279 PF09468.10 GAX16520.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain V-SNARE_C PF12352.8 GAX16521.1 - 2.4e-06 27.8 2.8 2.4e-06 27.8 2.8 2.2 3 0 0 3 3 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAX16521.1 - 1.8e-05 24.5 3.5 6.5e-05 22.8 2.4 2.2 1 1 1 2 2 2 1 Sec20 V-SNARE PF05008.15 GAX16521.1 - 0.0011 19.3 4.6 0.0011 19.3 4.6 2.6 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus RPW8 PF05659.11 GAX16521.1 - 0.0012 18.5 5.3 0.22 11.2 0.7 2.3 2 0 0 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4407 PF14362.6 GAX16521.1 - 0.0014 18.1 6.4 0.0017 17.7 6.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Val_tRNA-synt_C PF10458.9 GAX16521.1 - 0.0083 16.4 0.2 0.0083 16.4 0.2 3.1 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm DUF5435 PF17503.2 GAX16521.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Rhamno_transf PF11316.8 GAX16521.1 - 0.029 13.8 0.8 0.041 13.3 0.8 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase EMP24_GP25L PF01105.24 GAX16521.1 - 0.15 12.0 3.6 0.85 9.5 0.3 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 GAX16521.1 - 0.19 11.8 10.7 0.38 10.8 1.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2721 PF11026.8 GAX16521.1 - 0.47 10.4 1.8 0.56 10.1 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) SNARE PF05739.19 GAX16521.1 - 0.53 10.3 9.2 0.15 12.0 5.5 2.1 2 1 0 2 2 2 0 SNARE domain XhlA PF10779.9 GAX16521.1 - 0.62 10.3 10.0 0.29 11.3 2.0 3.0 3 0 0 3 3 3 0 Haemolysin XhlA PEP-utilisers_N PF05524.13 GAX16521.1 - 0.77 9.9 7.8 6.1 7.0 0.4 2.7 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal Cauli_AT PF03233.13 GAX16521.1 - 1.2 9.0 8.7 0.37 10.7 1.1 2.5 2 1 1 3 3 3 0 Aphid transmission protein TSNAXIP1_N PF15739.5 GAX16521.1 - 1.5 9.2 9.4 0.99 9.8 1.9 2.5 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus CLZ PF16526.5 GAX16521.1 - 1.7 9.1 9.1 0.63 10.4 1.1 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Enkurin PF13864.6 GAX16521.1 - 3 8.3 11.0 0.54 10.7 2.4 2.4 2 1 0 2 2 2 0 Calmodulin-binding DUF641 PF04859.12 GAX16521.1 - 4.5 7.6 10.6 16 5.9 0.9 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) C2 PF00168.30 GAX16522.1 - 5.1e-24 84.5 0.0 3.2e-10 40.2 0.0 3.3 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.5 GAX16522.1 - 1.4e-18 67.0 0.1 2.4e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Ank_4 PF13637.6 GAX16523.1 - 5.3e-22 77.9 0.4 1.1e-11 45.0 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX16523.1 - 1.8e-21 76.5 0.0 4.5e-16 59.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX16523.1 - 3.6e-16 57.6 0.1 5.6e-05 23.2 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAX16523.1 - 7.9e-15 54.7 0.2 0.0001 22.5 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX16523.1 - 1.1e-14 54.2 1.3 3.2e-05 24.2 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF1194 PF06707.11 GAX16523.1 - 0.15 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) mTERF PF02536.14 GAX16525.1 - 2.2e-44 151.6 1.9 7.1e-21 74.4 0.1 3.2 1 1 2 3 3 3 3 mTERF DUF1732 PF08340.11 GAX16525.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) HTH_26 PF13443.6 GAX16525.1 - 0.19 12.2 0.4 2.7 8.5 0.0 3.0 3 1 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain ArsC PF03960.15 GAX16525.1 - 0.71 9.9 2.8 14 5.7 0.0 3.3 4 0 0 4 4 4 0 ArsC family FtsH_ext PF06480.15 GAX16527.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 FtsH Extracellular His_Phos_2 PF00328.22 GAX16529.1 - 3.3e-20 72.8 0.0 5.5e-16 58.9 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) E3_UFM1_ligase PF09743.9 GAX16530.1 - 3.8e-06 26.7 0.0 7.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 adh_short_C2 PF13561.6 GAX16531.1 - 2.4e-35 122.2 0.0 3e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX16531.1 - 3.1e-18 65.9 0.0 3.7e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX16531.1 - 8e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAX16531.1 - 0.26 11.2 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cullin PF00888.22 GAX16533.1 - 3.2e-161 538.0 11.7 4.4e-161 537.6 11.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAX16533.1 - 3.4e-25 87.8 0.7 1.4e-24 85.9 0.7 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain TraA PF05513.11 GAX16533.1 - 0.024 15.0 0.1 0.071 13.5 0.1 1.8 1 0 0 1 1 1 0 TraA ATC_hydrolase PF14196.6 GAX16533.1 - 0.064 14.0 0.3 3.1 8.6 0.2 2.8 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Glyco_transf_8 PF01501.20 GAX16534.1 - 3.8e-15 56.1 0.3 5e-14 52.5 0.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GAX16534.1 - 0.002 17.6 0.4 0.0032 16.9 0.4 1.4 1 1 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_34 PF05637.12 GAX16534.1 - 0.097 12.4 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family PPR_2 PF13041.6 GAX16535.1 - 8.3e-30 102.7 5.8 2.9e-06 27.4 0.0 11.6 7 5 6 13 13 13 9 PPR repeat family PPR_1 PF12854.7 GAX16535.1 - 1.5e-22 79.0 0.0 0.00037 20.1 0.0 8.9 10 0 0 10 10 10 4 PPR repeat PPR_3 PF13812.6 GAX16535.1 - 6.7e-21 74.1 0.1 5.6e-07 29.5 0.0 8.1 6 2 3 9 9 9 2 Pentatricopeptide repeat domain PPR PF01535.20 GAX16535.1 - 3.3e-19 67.7 17.5 0.0034 17.5 0.0 11.4 12 2 0 12 12 12 5 PPR repeat PPR_long PF17177.4 GAX16535.1 - 7.1e-10 38.6 10.4 0.006 16.0 0.0 5.7 1 1 4 6 6 6 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GAX16535.1 - 0.023 15.5 2.1 12 7.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MNE1 PF13762.6 GAX16535.1 - 0.064 13.2 0.0 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component RE_XcyI PF09571.10 GAX16535.1 - 0.096 11.9 0.0 0.26 10.5 0.0 1.7 1 0 0 1 1 1 0 XcyI restriction endonuclease TPR_4 PF07721.14 GAX16535.1 - 0.12 13.0 0.6 2.6 8.9 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RPM2 PF08579.11 GAX16535.1 - 0.14 12.6 0.0 5.5 7.4 0.0 3.0 3 0 0 3 3 2 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 GAX16535.1 - 1.1 9.4 2.9 4.8 7.5 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX16535.1 - 4.7 7.2 9.2 0.43 10.5 0.3 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat XRN_M PF17846.1 GAX16536.1 - 3.4e-128 428.4 1.4 1.8e-86 290.9 0.1 2.4 1 1 0 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 GAX16536.1 - 2.3e-98 328.5 0.2 6.3e-98 327.0 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Carn_acyltransf PF00755.20 GAX16537.1 - 1.8e-168 561.8 0.0 2.1e-168 561.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF4332 PF14229.6 GAX16537.1 - 1.5 9.1 5.2 0.41 10.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) PAP_assoc PF03828.19 GAX16538.1 - 2.5e-05 24.4 1.0 0.00011 22.3 1.0 2.2 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF1877 PF08974.10 GAX16538.1 - 0.0013 18.8 1.6 0.071 13.2 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1877) NTP_transf_2 PF01909.23 GAX16538.1 - 0.054 13.8 0.1 0.21 11.9 0.1 2.1 1 0 0 1 1 1 0 Nucleotidyltransferase domain SHOCT PF09851.9 GAX16538.1 - 0.072 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Short C-terminal domain Agenet PF05641.12 GAX16539.1 - 0.00069 20.0 0.2 0.025 15.0 0.0 2.7 2 1 0 2 2 2 1 Agenet domain Iso_dh PF00180.20 GAX16541.1 - 1.8e-21 76.7 0.0 4.1e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_1 PF00036.32 GAX16541.1 - 2.2e-09 36.2 0.5 5.8e-09 34.9 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 GAX16541.1 - 3.8e-07 29.3 0.2 9e-07 28.1 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX16541.1 - 4.7e-06 26.1 0.1 1.9e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAX16541.1 - 0.00011 22.5 0.1 0.00037 20.9 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX16541.1 - 0.00023 21.0 0.2 0.00071 19.4 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair DHO_dh PF01180.21 GAX16543.1 - 1.7e-54 185.0 0.0 2.1e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 GAX16543.1 - 0.00011 21.4 0.3 0.00021 20.4 0.1 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 GAX16543.1 - 0.0026 17.2 0.3 0.0044 16.5 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 GAX16543.1 - 0.049 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase Fe-S_biosyn PF01521.20 GAX16544.1 - 3.8e-16 59.3 0.0 5.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis S1 PF00575.23 GAX16545.1 - 1.4e-06 28.5 0.1 3.5e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_3_Rpc31 PF11705.8 GAX16545.1 - 0.22 11.8 16.2 0.34 11.1 16.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GAX16545.1 - 0.28 10.5 12.1 0.43 9.9 12.1 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3245 PF11595.8 GAX16545.1 - 0.38 11.2 5.2 0.81 10.2 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Cwf_Cwc_15 PF04889.12 GAX16545.1 - 2.7 7.7 12.6 4.1 7.1 12.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YebO PF13974.6 GAX16545.1 - 3.7 7.7 5.6 1.7 8.7 2.7 1.9 2 0 0 2 2 2 0 YebO-like protein JmjC PF02373.22 GAX16546.1 - 1.4e-36 125.3 1.2 2e-36 124.9 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase E1-E2_ATPase PF00122.20 GAX16548.1 - 1.1e-47 161.9 1.2 2.4e-47 160.8 1.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAX16548.1 - 1.2e-26 94.4 0.0 4.4e-26 92.5 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAX16548.1 - 0.0013 19.1 12.3 0.003 18.0 0.0 5.1 6 1 0 6 6 6 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAX16548.1 - 0.0021 17.8 0.4 0.055 13.2 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX16548.1 - 0.016 15.6 0.0 2.6 8.4 0.0 2.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ninjurin PF04923.12 GAX16548.1 - 0.025 14.5 0.9 0.059 13.3 0.9 1.6 1 0 0 1 1 1 0 Ninjurin DAO PF01266.24 GAX16549.1 - 2.7e-33 116.0 0.0 3.1e-32 112.5 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX16549.1 - 2.3e-07 30.9 0.0 0.0015 18.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAX16549.1 - 9e-07 28.4 0.0 0.026 13.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX16549.1 - 0.00098 19.3 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX16549.1 - 0.019 14.1 0.0 0.62 9.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 GAX16549.1 - 0.033 13.1 0.1 0.47 9.2 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Dor1 PF04124.12 GAX16549.1 - 0.22 10.2 0.1 0.34 9.6 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family Octopine_DH PF02317.17 GAX16550.1 - 7.9e-26 90.9 0.0 1.2e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain ApbA PF02558.16 GAX16550.1 - 4.3e-05 23.2 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 GAX16550.1 - 0.0011 19.5 0.0 0.0028 18.2 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 GAX16550.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 GAX16550.1 - 0.052 13.5 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 GAX16550.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DP PF08781.10 GAX16552.1 - 2.8e-31 108.2 2.7 5.3e-31 107.3 2.7 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 GAX16552.1 - 2.2e-22 78.9 0.5 2.2e-22 78.9 0.5 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain ASFV_J13L PF05568.11 GAX16553.1 - 0.039 13.7 0.3 0.08 12.7 0.3 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Med9 PF07544.13 GAX16554.1 - 0.0039 17.2 8.1 0.01 15.9 3.3 3.0 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Glyco_hydro_115 PF15979.5 GAX16554.1 - 0.053 13.0 0.4 0.11 11.9 0.4 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 Retrotrans_gag PF03732.17 GAX16554.1 - 2.6 8.4 7.3 13 6.2 3.7 3.3 3 1 0 3 3 3 0 Retrotransposon gag protein SNF2_N PF00176.23 GAX16556.1 - 1.5e-56 191.6 0.0 2.6e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX16556.1 - 1.6e-15 57.4 0.0 5.1e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.8 GAX16556.1 - 7.3e-07 28.8 0.0 2.4e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) HEAT PF02985.22 GAX16556.1 - 0.00021 21.3 4.2 1.4 9.3 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat HDA2-3 PF11496.8 GAX16556.1 - 0.0021 17.3 0.0 0.0052 16.0 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 GAX16556.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase CLASP_N PF12348.8 GAX16556.1 - 0.053 13.1 0.2 0.2 11.2 0.2 2.0 2 0 0 2 2 2 0 CLASP N terminal Sir1 PF11603.8 GAX16556.1 - 0.096 13.2 0.1 0.29 11.6 0.1 1.8 1 0 0 1 1 1 0 Regulatory protein Sir1 HILPDA PF15220.6 GAX16556.1 - 0.19 11.9 2.9 1.2 9.3 0.1 3.0 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated HMG-CoA_red PF00368.18 GAX16557.1 - 2.8e-135 451.1 8.2 3.5e-135 450.7 8.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Pex24p PF06398.11 GAX16557.1 - 0.029 13.4 0.1 0.042 12.8 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PhnI PF05861.12 GAX16557.1 - 0.066 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Pribosyl_synth PF14572.6 GAX16557.1 - 0.3 11.1 2.0 0.69 9.9 0.5 2.0 2 0 0 2 2 2 0 Phosphoribosyl synthetase-associated domain Mito_carr PF00153.27 GAX16558.1 - 3.5e-33 113.4 23.3 4.2e-14 52.2 0.0 4.6 4 2 0 4 4 3 3 Mitochondrial carrier protein DUF2722 PF10846.8 GAX16558.1 - 0.00026 20.1 5.3 0.00036 19.6 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 GAX16558.1 - 0.0016 18.5 7.5 0.0021 18.1 7.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAX16558.1 - 0.026 14.1 16.3 0.045 13.4 16.3 1.3 1 0 0 1 1 1 0 Spt20 family DUF2721 PF11026.8 GAX16558.1 - 0.035 14.0 0.1 0.091 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Asparaginase_2 PF01112.18 GAX16558.1 - 0.04 12.9 0.1 0.064 12.3 0.1 1.3 1 0 0 1 1 1 0 Asparaginase Peroxin-13_N PF04088.13 GAX16558.1 - 0.052 13.8 0.1 0.083 13.2 0.1 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region 7TM_GPCR_Srd PF10317.9 GAX16558.1 - 0.061 12.5 0.7 0.2 10.8 0.1 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd Longin PF13774.6 GAX16558.1 - 0.063 13.3 0.3 0.3 11.1 0.1 2.2 3 0 0 3 3 3 0 Regulated-SNARE-like domain SUIM_assoc PF16619.5 GAX16558.1 - 0.2 11.7 19.7 5.3 7.2 18.6 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 GAX16558.1 - 0.43 11.6 6.1 0.098 13.6 2.6 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 GAX16558.1 - 0.6 9.0 25.0 0.94 8.4 25.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Roughex PF06020.11 GAX16558.1 - 0.7 8.9 3.5 1.9 7.5 3.6 1.6 2 0 0 2 2 2 0 Drosophila roughex protein Pex14_N PF04695.13 GAX16558.1 - 3.3 8.4 11.0 9.5 6.9 9.2 2.4 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region E_Pc_C PF06752.12 GAX16558.1 - 6 6.9 24.1 1.2 9.2 17.0 2.1 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus DAO PF01266.24 GAX16559.1 - 1.4e-57 195.9 0.0 2.9e-36 125.8 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Fer2_BFD PF04324.15 GAX16559.1 - 2.7e-10 40.4 3.3 6.5e-10 39.2 3.3 1.7 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain FAD_binding_3 PF01494.19 GAX16559.1 - 5.7e-05 22.5 0.7 0.0049 16.2 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 GAX16559.1 - 6.4e-05 23.4 0.4 0.33 11.5 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAX16559.1 - 0.00014 21.3 0.2 0.023 13.9 0.1 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX16559.1 - 0.0059 15.7 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAX16559.1 - 0.01 16.0 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 GAX16559.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MRG PF05712.13 GAX16560.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 MRG VKOR PF07884.14 GAX16561.1 - 1.3e-22 80.3 7.4 1.3e-22 80.3 7.4 2.0 2 0 0 2 2 2 1 Vitamin K epoxide reductase family Thioredoxin PF00085.20 GAX16561.1 - 0.068 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 GAX16561.1 - 0.079 13.1 0.2 0.87 9.7 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DUF2070 PF09843.9 GAX16561.1 - 0.62 8.3 4.1 0.81 7.9 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zinc_ribbon_6 PF14599.6 GAX16562.1 - 1.8e-18 66.3 0.5 1.8e-18 66.3 0.5 3.9 2 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 GAX16562.1 - 5.7e-15 55.6 14.2 5.7e-15 55.6 14.2 5.0 2 2 0 2 2 2 1 CHY zinc finger zf-RING_2 PF13639.6 GAX16562.1 - 4.6e-09 36.5 9.4 4.6e-09 36.5 9.4 5.2 5 1 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 GAX16562.1 - 3.6e-05 23.6 8.0 3.6e-05 23.6 8.0 5.5 5 3 1 6 6 6 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX16562.1 - 0.0011 18.9 3.3 0.0011 18.9 3.3 5.6 6 0 0 6 6 6 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX16562.1 - 0.0012 18.6 8.3 0.0012 18.6 8.3 5.4 5 1 1 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX16562.1 - 0.0018 18.1 6.8 0.0018 18.1 6.8 5.6 3 2 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 GAX16562.1 - 0.0043 17.0 3.8 0.0043 17.0 3.8 3.3 3 1 1 4 4 4 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 GAX16562.1 - 0.0062 16.4 3.6 0.0062 16.4 3.6 5.4 3 2 2 5 5 5 2 Prokaryotic RING finger family 4 Rubredoxin_2 PF18073.1 GAX16562.1 - 0.049 13.4 0.5 0.049 13.4 0.5 6.5 8 1 0 8 8 8 0 Rubredoxin metal binding domain HisKA_7TM PF16927.5 GAX16563.1 - 0.00013 22.1 14.2 0.00031 20.9 13.2 2.1 1 1 1 2 2 2 1 N-terminal 7TM region of histidine kinase DUF3169 PF11368.8 GAX16563.1 - 0.025 14.1 2.4 0.083 12.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4381 PF14316.6 GAX16563.1 - 1.6 9.0 6.3 11 6.2 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) Ank_2 PF12796.7 GAX16564.1 - 8.2e-05 23.1 0.0 0.00023 21.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX16564.1 - 0.00058 20.1 0.0 0.013 15.8 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX16564.1 - 0.00066 20.2 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Syntaxin_2 PF14523.6 GAX16564.1 - 0.0036 17.7 4.9 0.0036 17.7 4.9 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Flu_M1_C PF08289.11 GAX16564.1 - 0.15 12.3 2.6 0.53 10.5 0.4 2.8 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain LMBR1 PF04791.16 GAX16564.1 - 0.53 9.1 6.0 0.8 8.5 6.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Meis_PKNOX_N PF16493.5 GAX16565.1 - 0.078 13.3 1.3 0.2 12.0 0.3 2.0 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 ABC1 PF03109.16 GAX16566.1 - 2e-29 102.2 0.0 4.7e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX16566.1 - 0.00015 21.7 0.7 0.12 12.3 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX16566.1 - 0.084 11.6 0.0 0.16 10.7 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase PPR_2 PF13041.6 GAX16569.1 - 2.1e-59 197.5 12.5 1.1e-11 44.8 0.0 9.7 1 1 9 10 10 10 8 PPR repeat family PPR_3 PF13812.6 GAX16569.1 - 1.7e-50 169.0 0.0 1.3e-11 44.4 0.0 6.7 1 1 6 9 9 9 9 Pentatricopeptide repeat domain PPR PF01535.20 GAX16569.1 - 1.8e-48 159.5 22.2 8.8e-06 25.6 0.1 11.2 11 0 0 11 11 11 8 PPR repeat PPR_1 PF12854.7 GAX16569.1 - 1.6e-31 107.7 0.0 5.9e-05 22.7 0.0 9.4 8 1 0 8 8 8 7 PPR repeat PPR_long PF17177.4 GAX16569.1 - 7.6e-26 90.8 4.3 1.3e-09 37.7 0.1 3.4 1 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 GAX16569.1 - 0.044 12.9 0.1 0.2 10.7 0.0 2.1 2 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF2594 PF10769.9 GAX16569.1 - 0.11 12.5 0.1 15 5.7 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2594) ANAPC3 PF12895.7 GAX16569.1 - 0.23 11.7 1.5 38 4.6 0.0 3.3 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF982 PF06169.12 GAX16569.1 - 4.1 7.5 5.0 2.7 8.1 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF982) VPS9 PF02204.18 GAX16570.1 - 1.5e-09 38.0 1.1 2.2e-09 37.5 0.3 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Bacteriocin_IIc PF10439.9 GAX16570.1 - 0.0027 17.8 3.1 0.0027 17.8 3.1 2.9 2 1 1 3 3 3 1 Bacteriocin class II with double-glycine leader peptide Prok-RING_1 PF14446.6 GAX16570.1 - 0.011 15.6 5.9 0.011 15.6 5.9 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 RUN PF02759.19 GAX16570.1 - 0.088 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 RUN domain Phage_holin_5_2 PF16079.5 GAX16570.1 - 2.4 8.6 5.6 5.9 7.3 5.6 1.6 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Transketolase_N PF00456.21 GAX16572.1 - 1.3e-108 362.9 2.0 1.8e-108 362.5 2.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAX16572.1 - 9.2e-35 119.9 0.0 1.8e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX16572.1 - 2.5e-08 33.8 0.0 6.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAX16572.1 - 1.6e-06 27.6 0.0 7e-05 22.2 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 GAX16572.1 - 0.0045 16.0 0.1 0.0089 15.0 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4275 PF14101.6 GAX16572.1 - 0.14 12.3 0.8 0.3 11.2 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) Peptidase_S26 PF10502.9 GAX16573.1 - 9.2e-05 22.2 0.0 0.091 12.6 0.0 2.4 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 EPV_E5 PF08135.11 GAX16573.1 - 0.93 9.9 3.4 2.2 8.7 3.4 1.5 1 0 0 1 1 1 0 Major transforming protein E5 family PseudoU_synth_1 PF01416.20 GAX16574.1 - 1e-18 67.8 5.9 7.5e-13 48.9 0.1 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF2722 PF10846.8 GAX16574.1 - 0.0014 17.6 7.2 0.0014 17.6 7.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 GAX16574.1 - 0.0033 17.1 13.4 0.0049 16.5 13.4 1.3 1 0 0 1 1 1 1 Spt20 family DUF2126 PF09899.9 GAX16574.1 - 0.0044 15.2 2.2 0.0061 14.7 2.2 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) TFIIA PF03153.13 GAX16574.1 - 0.006 16.6 9.8 0.0088 16.1 9.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DMAP1 PF05499.12 GAX16574.1 - 0.0078 16.1 1.3 0.014 15.3 1.3 1.4 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Androgen_recep PF02166.16 GAX16574.1 - 0.012 14.5 7.0 0.017 14.0 7.0 1.2 1 0 0 1 1 1 0 Androgen receptor Med15 PF09606.10 GAX16574.1 - 0.023 13.4 11.3 0.03 13.0 11.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MMR1 PF08505.10 GAX16574.1 - 0.053 13.8 5.8 0.071 13.4 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RAB3GAP2_N PF14655.6 GAX16574.1 - 0.074 12.3 3.4 0.12 11.6 3.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RNA_helicase PF00910.22 GAX16574.1 - 0.13 12.7 0.4 0.34 11.3 0.4 1.7 1 0 0 1 1 1 0 RNA helicase Med3 PF11593.8 GAX16574.1 - 2.1 7.4 13.1 3.1 6.9 13.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Suf PF05843.14 GAX16574.1 - 2.6 7.9 9.4 1.2 9.0 6.6 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Aldolase_II PF00596.21 GAX16575.1 - 9.6e-42 143.0 0.0 1.5e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HAD_2 PF13419.6 GAX16575.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX16575.1 - 0.0053 17.1 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX16575.1 - 0.029 14.4 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like PBP1_TM PF14812.6 GAX16575.1 - 0.51 10.7 3.0 1.1 9.7 3.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_6 PF12774.7 GAX16576.1 - 6e-128 426.4 0.0 8e-127 422.7 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GAX16576.1 - 3.4e-105 352.4 0.1 3.4e-105 352.4 0.1 4.3 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 GAX16576.1 - 2.4e-76 257.6 8.8 2.4e-76 257.6 8.8 3.5 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 GAX16576.1 - 2.2e-67 226.4 0.0 2.2e-67 226.4 0.0 3.0 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 GAX16576.1 - 1.2e-61 208.3 0.0 4.3e-61 206.5 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 GAX16576.1 - 3.5e-36 124.9 7.0 3.5e-36 124.9 7.0 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 GAX16576.1 - 4.7e-36 124.0 0.0 2.4e-32 111.9 0.0 4.1 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 GAX16576.1 - 4.3e-28 98.2 0.0 1e-27 96.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GAX16576.1 - 1.2e-24 86.7 0.0 2.2e-23 82.6 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 GAX16576.1 - 1.5e-22 80.1 0.0 4.6e-08 33.2 0.0 6.9 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 GAX16576.1 - 1e-16 61.2 2.3 3e-16 59.7 0.1 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 GAX16576.1 - 3.2e-13 50.3 0.0 0.0022 18.4 0.0 4.3 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX16576.1 - 4.6e-07 30.4 1.7 2.6 8.4 0.0 6.6 6 0 0 6 6 5 2 AAA ATPase domain T2SSE PF00437.20 GAX16576.1 - 4.1e-06 26.1 0.0 0.018 14.1 0.0 4.7 5 0 0 5 5 5 1 Type II/IV secretion system protein AAA_18 PF13238.6 GAX16576.1 - 2e-05 25.1 0.0 2.8 8.5 0.0 5.2 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 GAX16576.1 - 2.7e-05 24.4 0.5 0.077 13.2 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 GAX16576.1 - 3e-05 24.3 17.0 0.067 13.5 0.0 8.0 10 1 1 11 11 7 2 AAA domain AAA_lid_1 PF17857.1 GAX16576.1 - 7.4e-05 22.9 0.0 0.00036 20.7 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 GAX16576.1 - 0.00035 20.0 0.2 2.8 7.2 0.0 4.1 4 0 0 4 4 4 1 FtsK/SpoIIIE family Jnk-SapK_ap_N PF09744.9 GAX16576.1 - 0.00074 19.8 0.8 0.00074 19.8 0.8 4.0 4 0 0 4 4 1 1 JNK_SAPK-associated protein-1 BRE1 PF08647.11 GAX16576.1 - 0.00075 19.5 4.6 0.00075 19.5 4.6 4.8 4 0 0 4 4 2 1 BRE1 E3 ubiquitin ligase AAA_25 PF13481.6 GAX16576.1 - 0.0012 18.5 0.1 0.16 11.5 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAX16576.1 - 0.0065 16.2 1.5 4.4 7.0 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 GAX16576.1 - 0.0081 16.5 0.8 0.56 10.5 0.0 3.8 3 0 0 3 3 3 1 AAA domain RBD PF02196.15 GAX16576.1 - 0.02 15.0 0.1 5.8 7.1 0.0 3.1 2 0 0 2 2 2 0 Raf-like Ras-binding domain TsaE PF02367.17 GAX16576.1 - 0.058 13.4 1.0 5.2 7.1 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 GAX16576.1 - 0.059 13.3 0.0 11 5.9 0.0 3.2 3 0 0 3 3 2 0 RsgA GTPase RuvB_N PF05496.12 GAX16576.1 - 0.069 12.9 0.1 2.4 7.9 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAX16576.1 - 0.082 12.6 0.2 4.4 7.0 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein Rad17 PF03215.15 GAX16576.1 - 0.099 12.6 0.8 31 4.4 0.0 4.0 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_24 PF13479.6 GAX16576.1 - 0.15 11.8 0.5 46 3.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain zf-C4H2 PF10146.9 GAX16576.1 - 0.27 11.5 14.4 0.041 14.2 0.3 3.1 2 0 0 2 2 2 0 Zinc finger-containing protein Drf_GBD PF06371.13 GAX16576.1 - 0.55 9.8 4.0 0.98 9.0 2.1 2.3 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Mg_chelatase PF01078.21 GAX16576.1 - 0.63 9.4 5.4 2.7 7.3 0.1 3.2 3 1 0 3 3 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 GAX16576.1 - 1.1 9.8 3.2 21 5.6 0.0 4.3 5 0 0 5 5 2 0 ABC transporter Ion_trans_2 PF07885.16 GAX16577.1 - 1.8e-52 175.2 50.2 2.3e-14 53.1 4.8 4.2 4 0 0 4 4 4 4 Ion channel Lig_chan PF00060.26 GAX16577.1 - 2e-05 24.5 21.3 0.00097 19.0 0.1 4.1 1 1 2 4 4 4 2 Ligand-gated ion channel IRK PF01007.20 GAX16577.1 - 0.0064 16.3 11.7 2.1 8.2 0.1 4.6 4 1 0 4 4 4 2 Inward rectifier potassium channel transmembrane domain Sec61_beta PF03911.16 GAX16577.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.7 5 0 0 5 5 5 0 Sec61beta family OppC_N PF12911.7 GAX16577.1 - 8.6 6.4 7.6 6.4 6.8 0.1 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Ras PF00071.22 GAX16578.1 - 4.1e-61 205.3 0.1 4.9e-61 205.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX16578.1 - 3.9e-36 123.9 0.1 6.7e-36 123.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX16578.1 - 1.4e-15 57.2 0.0 1.8e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX16578.1 - 2.8e-07 30.6 0.0 4.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX16578.1 - 1.2e-05 25.3 0.1 0.018 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAX16578.1 - 1.3e-05 24.8 0.1 5.4e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAX16578.1 - 0.0011 18.5 0.1 0.19 11.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAX16578.1 - 0.0012 19.3 0.1 0.0022 18.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 GAX16578.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 GAX16578.1 - 0.0016 18.7 0.0 0.014 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX16578.1 - 0.0033 18.0 0.4 0.024 15.2 0.4 2.1 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 GAX16578.1 - 0.0077 16.0 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 GAX16578.1 - 0.016 14.4 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 GAX16578.1 - 0.02 14.6 0.1 0.046 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 GAX16578.1 - 0.022 14.2 0.0 0.044 13.2 0.0 1.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 GAX16578.1 - 0.026 14.5 0.0 0.066 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 GAX16578.1 - 0.036 13.5 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein DUF2868 PF11067.8 GAX16578.1 - 0.064 12.8 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Ploopntkinase3 PF18751.1 GAX16578.1 - 0.091 12.7 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MCM PF00493.23 GAX16578.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 GAX16578.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.6 1 1 0 1 1 1 0 NTPase Lipase_3 PF01764.25 GAX16579.1 - 1.5e-23 83.3 0.0 3e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) CrtC PF07143.11 GAX16580.1 - 0.0066 17.1 0.3 0.0084 16.8 0.3 1.1 1 0 0 1 1 1 1 CrtC N-terminal lipocalin domain Folate_rec PF03024.14 GAX16580.1 - 0.01 15.7 0.5 0.014 15.3 0.5 1.3 1 0 0 1 1 1 0 Folate receptor family Peptidase_S9_N PF02897.15 GAX16580.1 - 0.042 12.6 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Phage_int_SAM_4 PF13495.6 GAX16581.1 - 0.0084 16.6 0.2 0.041 14.3 0.0 2.4 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.25 GAX16582.1 - 6.4e-72 242.1 0.0 8e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16582.1 - 6.1e-33 114.2 0.0 9.2e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX16582.1 - 3.2e-06 26.3 0.0 7.7e-05 21.8 0.0 2.6 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 GAX16582.1 - 0.00034 20.0 0.1 0.001 18.5 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 GAX16582.1 - 0.00094 19.2 0.1 0.005 16.8 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX16582.1 - 0.0037 16.6 0.0 0.008 15.5 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Costars PF14705.6 GAX16582.1 - 0.16 12.2 0.0 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Costars PGI PF00342.19 GAX16583.1 - 5.3e-189 628.9 0.0 6.5e-189 628.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF3992 PF13157.6 GAX16583.1 - 0.0068 17.1 0.1 0.016 15.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3992) SUIM_assoc PF16619.5 GAX16583.1 - 6.9 6.8 17.3 3 8.0 6.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_M3 PF01432.20 GAX16584.1 - 7.9e-100 335.3 1.4 1.2e-99 334.7 1.4 1.2 1 0 0 1 1 1 1 Peptidase family M3 TFIID_NTD2 PF04494.15 GAX16584.1 - 0.007 16.6 0.1 0.02 15.1 0.1 1.8 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain DUF1319 PF07028.11 GAX16584.1 - 0.093 13.0 0.3 26 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Peptidase_M50B PF13398.6 GAX16584.1 - 2.5 7.7 5.8 0.19 11.3 0.6 1.7 2 0 0 2 2 2 0 Peptidase M50B-like DUF3439 PF11921.8 GAX16584.1 - 7.2 6.6 9.8 0.12 12.3 1.7 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Amino_oxidase PF01593.24 GAX16585.1 - 1.4e-53 182.8 0.0 1.6e-53 182.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX16585.1 - 4.8e-07 29.9 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX16585.1 - 0.0014 18.3 0.0 0.0063 16.1 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX16585.1 - 0.025 13.7 0.0 0.33 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 GAX16585.1 - 0.035 13.5 0.0 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase CooC_C PF15976.5 GAX16585.1 - 0.046 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 CS1-pili formation C-terminal Pyr_redox_2 PF07992.14 GAX16585.1 - 0.11 11.7 0.1 0.54 9.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAX16585.1 - 0.31 10.1 1.6 2.8 7.0 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Acetyltransf_7 PF13508.7 GAX16586.1 - 2.7e-08 34.1 0.1 4.4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX16586.1 - 1.9e-06 28.1 0.0 2.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX16586.1 - 2e-06 27.8 0.1 2.3e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX16586.1 - 5.7e-05 23.2 0.1 0.00011 22.3 0.1 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX16586.1 - 0.0016 18.3 0.0 0.0073 16.2 0.0 1.8 1 1 1 2 2 2 1 FR47-like protein GNAT_acetyltr_2 PF13718.6 GAX16586.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_CG PF14542.6 GAX16586.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Methyltransf_21 PF05050.12 GAX16587.1 - 5.2e-13 49.4 0.1 1e-12 48.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase FkbM domain CDP-OH_P_transf PF01066.21 GAX16588.1 - 5.8e-12 46.2 0.0 1.5e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF5341 PF17276.2 GAX16589.1 - 0.043 14.0 4.6 0.32 11.2 4.6 2.5 1 0 0 1 1 1 0 Family of unknown function (DUF5341) CcmH PF03918.14 GAX16589.1 - 0.15 11.4 6.9 0.075 12.3 0.7 2.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein NTNH_C PF08470.10 GAX16589.1 - 3 7.7 8.4 0.66 9.8 2.0 2.6 2 0 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal PNTB PF02233.16 GAX16590.1 - 1.4e-173 578.1 16.0 1.4e-173 578.1 16.0 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAX16590.1 - 5.6e-71 238.2 0.8 5.6e-71 238.2 0.8 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAX16590.1 - 2e-42 144.7 0.0 5e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAX16590.1 - 2.3e-26 92.1 10.3 2.3e-26 92.1 10.3 3.3 4 1 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 GAX16590.1 - 0.00014 21.3 0.1 0.03 13.7 0.1 3.6 4 0 0 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAX16590.1 - 0.0029 17.6 2.9 0.007 16.3 0.1 3.1 4 0 0 4 4 4 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 GAX16590.1 - 0.0088 15.3 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX16590.1 - 0.23 11.7 4.6 1.1 9.6 0.2 3.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Baculo_PEP_C PF04513.12 GAX16591.1 - 0.00034 20.7 1.4 0.00034 20.7 1.4 4.1 4 1 0 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 GAX16591.1 - 0.0051 17.3 10.6 0.0051 17.3 10.6 5.6 2 1 3 5 5 5 1 Apg6 coiled-coil region DUF1664 PF07889.12 GAX16591.1 - 0.0085 16.1 4.6 0.0085 16.1 4.6 5.2 3 1 4 7 7 7 1 Protein of unknown function (DUF1664) DUF3926 PF13080.6 GAX16591.1 - 0.38 10.7 3.2 0.54 10.2 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) ApoO PF09769.9 GAX16591.1 - 9.5 6.2 10.6 10 6.1 0.1 4.1 3 2 1 4 4 4 0 Apolipoprotein O UPRTase PF14681.6 GAX16592.1 - 7.8e-62 208.4 0.0 9.1e-62 208.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAX16592.1 - 0.05 13.1 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Herpes_UL87 PF03043.14 GAX16592.1 - 0.22 9.9 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4477 PF14780.6 GAX16593.1 - 0.087 12.4 0.5 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) RD3 PF14473.6 GAX16594.1 - 0.04 13.8 0.8 0.094 12.6 0.7 1.6 1 1 1 2 2 2 0 RD3 protein bZIP_1 PF00170.21 GAX16598.1 - 0.17 12.0 10.5 0.051 13.7 6.0 2.4 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 GAX16598.1 - 0.18 12.4 8.5 0.089 13.4 3.5 2.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 GAX16598.1 - 0.55 10.7 6.5 0.63 10.6 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF2968 PF11180.8 GAX16598.1 - 0.78 9.4 20.3 0.15 11.7 8.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) TMF_TATA_bd PF12325.8 GAX16598.1 - 0.85 9.9 10.5 0.72 10.1 3.3 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KIAA1430 PF13879.6 GAX16598.1 - 1.5 9.7 10.6 0.15 12.9 4.8 2.3 2 0 0 2 2 2 0 KIAA1430 homologue GIT_CC PF16559.5 GAX16598.1 - 6.7 6.7 9.1 3.2 7.7 2.4 3.0 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FIVAR PF07554.13 GAX16598.1 - 7.8 7.3 10.8 1 10.2 4.9 2.6 2 1 0 2 2 2 0 FIVAR domain Glycos_transf_1 PF00534.20 GAX16599.1 - 2.5e-32 111.8 0.0 4.1e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX16599.1 - 1.2e-26 93.7 0.0 2.2e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX16599.1 - 1e-21 77.7 0.2 4.5e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAX16599.1 - 4.3e-14 53.3 0.0 2.1e-13 51.0 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX16599.1 - 6.2e-12 45.7 0.0 8.1e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 GAX16599.1 - 0.027 14.5 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF962 PF06127.11 GAX16600.1 - 2.8e-08 33.7 4.1 9.5e-08 32.0 4.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) HisKA_7TM PF16927.5 GAX16600.1 - 0.0026 17.9 5.5 0.0031 17.6 5.5 1.2 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase TMEM189_B_dmain PF10520.9 GAX16603.1 - 4.8e-55 186.3 0.1 7.9e-55 185.6 0.1 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 GAX16603.1 - 4.1e-05 23.9 2.2 5e-05 23.7 0.3 1.9 1 1 0 2 2 2 1 Fatty acid hydroxylase superfamily bMG1 PF17970.1 GAX16603.1 - 0.2 11.8 0.3 8.3 6.5 0.0 2.5 2 1 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG1 domain Aldose_epim PF01263.20 GAX16605.1 - 7.9e-34 117.3 0.0 9.5e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Bud13 PF09736.9 GAX16607.1 - 4.7e-34 117.9 8.5 4.7e-34 117.9 8.5 3.8 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Chorismate_synt PF01264.21 GAX16607.1 - 0.024 13.4 1.9 0.034 12.8 1.9 1.3 1 0 0 1 1 1 0 Chorismate synthase Peptidase_S24 PF00717.23 GAX16608.1 - 7.7e-11 41.8 0.2 1.3e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase S24-like EMP24_GP25L PF01105.24 GAX16609.1 - 4.4e-18 65.9 0.0 5.2e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PhzC-PhzF PF02567.16 GAX16610.1 - 1.1e-53 182.5 0.1 1.6e-53 182.0 0.1 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 GAX16610.1 - 5.9e-08 33.0 0.0 1.6e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX16610.1 - 3.6e-07 30.5 0.0 8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX16610.1 - 2.3e-06 27.5 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX16610.1 - 0.00066 19.8 0.0 0.0059 16.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX16610.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 GAX16610.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase TFIIS_M PF07500.14 GAX16611.1 - 9.2e-20 71.2 0.2 5.8e-19 68.6 0.2 2.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PLU-1 PF08429.11 GAX16611.1 - 6.6e-07 28.8 6.6 0.022 14.0 0.0 4.9 3 2 2 5 5 5 2 PLU-1-like protein DUF745 PF05335.13 GAX16611.1 - 0.0019 18.0 0.3 0.0048 16.6 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Glyco_trans_4_5 PF16994.5 GAX16611.1 - 0.005 16.5 0.4 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl-transferase family 4 SPOC PF07744.13 GAX16611.1 - 0.0079 16.1 0.1 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 SPOC domain ComR_TPR PF18710.1 GAX16611.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 ComR tetratricopeptide GpcrRhopsn4 PF10192.9 GAX16613.1 - 1.8e-27 96.4 6.0 3e-27 95.6 6.0 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Cadherin_4 PF17803.1 GAX16615.1 - 0.15 12.7 1.7 0.17 12.6 0.5 1.6 2 0 0 2 2 2 0 Bacterial cadherin-like domain Kinesin PF00225.23 GAX16616.1 - 4.3e-16 58.7 0.0 2.2e-13 49.9 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GAX16616.1 - 1.5e-06 28.2 0.1 6.9e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Microtubule binding bZIP_1 PF00170.21 GAX16616.1 - 0.016 15.3 2.0 0.016 15.3 2.0 2.3 2 0 0 2 2 2 0 bZIP transcription factor NRBF2 PF08961.10 GAX16616.1 - 0.032 13.8 0.3 0.1 12.2 0.3 1.8 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator JIP_LZII PF16471.5 GAX16616.1 - 0.038 14.2 0.4 0.092 12.9 0.4 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_2 PF07716.15 GAX16616.1 - 0.46 10.6 4.5 0.24 11.5 0.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper PHD PF00628.29 GAX16617.1 - 3.8e-08 33.1 11.7 7.7e-08 32.1 11.7 1.5 1 0 0 1 1 1 1 PHD-finger PDZ_6 PF17820.1 GAX16617.1 - 9.6e-06 25.4 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain zf-HC5HC2H PF13771.6 GAX16617.1 - 0.0011 19.1 4.3 0.0011 19.1 4.3 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 GAX16617.1 - 0.0014 18.2 2.9 0.0027 17.2 2.9 1.5 1 0 0 1 1 1 1 PHD-finger PDZ PF00595.24 GAX16617.1 - 0.0022 18.3 0.0 0.19 12.1 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX16617.1 - 0.015 15.6 0.0 4.2 7.8 0.0 2.8 2 0 0 2 2 2 0 PDZ domain ELM2 PF01448.24 GAX16617.1 - 0.021 15.6 0.0 0.084 13.6 0.0 2.1 1 0 0 1 1 1 0 ELM2 domain TraC PF07820.12 GAX16617.1 - 0.022 15.1 0.6 0.74 10.2 0.2 2.4 2 0 0 2 2 2 0 TraC-like protein SNF2_N PF00176.23 GAX16618.1 - 1.4e-52 178.6 0.4 4.4e-52 176.9 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX16618.1 - 1.3e-14 54.4 0.0 4.7e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX16618.1 - 1e-11 45.2 0.0 3.3e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX16618.1 - 2e-06 27.7 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAX16618.1 - 1.3e-05 24.5 0.0 9.5e-05 21.7 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 GAX16618.1 - 0.019 14.6 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_34 PF13872.6 GAX16618.1 - 0.043 12.7 0.0 0.23 10.3 0.0 2.0 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF4611 PF15387.6 GAX16618.1 - 0.78 10.0 6.1 2.4 8.4 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MerC PF03203.14 GAX16619.1 - 1.9e-20 73.5 11.7 3.2e-20 72.8 11.7 1.4 1 0 0 1 1 1 1 MerC mercury resistance protein PSII_Pbs31 PF18240.1 GAX16622.1 - 4.5e-37 126.4 10.1 4.5e-37 126.4 10.1 1.6 2 0 0 2 2 2 1 Photosystem II Psb31 protein SnoaL PF07366.12 GAX16623.1 - 2.8e-27 95.0 0.0 3.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAX16623.1 - 2.5e-13 50.5 0.0 4.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Ribosomal_L22e PF01776.17 GAX16625.1 - 0.0063 16.9 2.2 0.0063 16.9 2.2 1.7 2 0 0 2 2 2 1 Ribosomal L22e protein family CCDC92 PF14916.6 GAX16625.1 - 0.015 15.1 5.1 0.04 13.7 3.6 2.6 2 1 1 3 3 3 0 Coiled-coil domain of unknown function PTS-HPr PF00381.19 GAX16625.1 - 0.055 13.7 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 PTS HPr component phosphorylation site DUF1223 PF06764.11 GAX16625.1 - 0.066 13.2 3.4 0.27 11.2 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1223) Vps35 PF03635.17 GAX16625.1 - 0.12 10.9 6.4 0.04 12.4 2.6 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 SpecificRecomb PF10136.9 GAX16625.1 - 0.66 8.2 3.9 1.5 7.0 3.9 1.6 1 0 0 1 1 1 0 Site-specific recombinase UPF0242 PF06785.11 GAX16625.1 - 1.1 9.4 14.9 0.25 11.4 7.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-K PF11802.8 GAX16625.1 - 1.5 8.4 17.5 0.031 13.9 8.1 2.3 2 0 0 2 2 2 0 Centromere-associated protein K Csm1_N PF18504.1 GAX16625.1 - 7.8 6.9 21.2 0.15 12.4 9.1 3.4 2 1 0 2 2 2 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 GAX16625.1 - 9.6 4.0 11.1 1.1 7.1 3.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Aph-1 PF06105.12 GAX16626.1 - 1e-26 93.8 12.3 6e-26 91.3 12.3 1.9 1 1 0 1 1 1 1 Aph-1 protein DUF1517 PF07466.11 GAX16627.1 - 6.6e-46 156.8 2.1 1.5e-45 155.6 1.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) LIM_bind PF01803.16 GAX16627.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.5 2 0 0 2 2 2 0 LIM-domain binding protein COP-gamma_platf PF08752.10 GAX16629.1 - 2.8e-07 30.8 0.0 4e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Vps39_2 PF10367.9 GAX16629.1 - 0.002 18.6 0.1 0.0048 17.3 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 NifU PF01106.17 GAX16630.1 - 4.5e-27 94.0 0.6 2.9e-21 75.4 0.4 2.2 2 0 0 2 2 2 2 NifU-like domain PAH PF02671.21 GAX16631.1 - 4.9e-39 132.2 4.9 1e-19 70.4 2.6 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAX16631.1 - 4.6e-18 65.1 0.7 1.3e-17 63.7 0.7 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor CHASE3 PF05227.13 GAX16631.1 - 6 6.8 13.3 0.031 14.2 2.9 2.4 3 0 0 3 3 3 0 CHASE3 domain Biopterin_H PF00351.21 GAX16634.1 - 2.1e-70 237.4 0.3 2.4e-70 237.2 0.3 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Sec6 PF06046.13 GAX16634.1 - 0.23 9.8 0.0 0.27 9.6 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Nop14 PF04147.12 GAX16635.1 - 2.2e-133 446.5 36.1 2.7e-133 446.2 36.1 1.0 1 0 0 1 1 1 1 Nop14-like family TUDOR_5 PF18359.1 GAX16635.1 - 6.8e-07 28.9 0.4 1.5e-06 27.8 0.4 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 GAX16635.1 - 0.0013 19.2 0.1 0.0036 17.7 0.1 1.8 1 0 0 1 1 1 1 Agenet domain DUF4399 PF14347.6 GAX16635.1 - 0.06 13.7 0.3 0.14 12.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) DUF5635 PF18685.1 GAX16635.1 - 0.13 12.3 0.2 0.56 10.2 0.2 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Tic22 PF04278.12 GAX16637.1 - 8.5e-08 31.9 0.0 3.2e-05 23.4 0.0 2.3 2 1 0 2 2 2 2 Tic22-like family Nnf1 PF03980.14 GAX16637.1 - 0.028 14.8 0.2 0.075 13.4 0.2 1.7 1 0 0 1 1 1 0 Nnf1 Sec7 PF01369.20 GAX16638.1 - 7.9e-59 198.4 0.0 1.9e-58 197.2 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAX16638.1 - 3.9e-36 124.3 2.7 3.9e-36 124.3 2.7 3.0 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAX16638.1 - 7.3e-28 96.3 0.9 2.2e-26 91.5 0.1 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DCB PF16213.5 GAX16638.1 - 6.5e-12 45.5 2.4 3.5e-10 39.9 0.6 2.9 2 0 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 Arm PF00514.23 GAX16638.1 - 0.11 12.6 0.5 0.57 10.3 0.1 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat TRAM_LAG1_CLN8 PF03798.16 GAX16639.1 - 6.4e-26 91.3 26.2 7.3e-25 87.9 26.2 2.3 1 1 0 1 1 1 1 TLC domain SLC3A2_N PF16028.5 GAX16639.1 - 2 8.0 4.2 1.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus GMC_oxred_N PF00732.19 GAX16640.1 - 3.6e-38 131.6 0.0 5.5e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAX16640.1 - 8.2e-26 91.2 0.0 1.4e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAX16640.1 - 0.00011 21.4 0.3 0.00017 20.8 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAX16640.1 - 0.0011 18.3 0.1 0.002 17.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAX16640.1 - 0.0021 17.3 0.0 0.0053 16.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX16640.1 - 0.0038 16.5 0.1 0.0074 15.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX16640.1 - 0.0087 15.0 0.2 0.012 14.4 0.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 GAX16640.1 - 0.0087 14.8 0.2 0.023 13.4 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 GAX16640.1 - 0.03 13.9 0.5 0.066 12.8 0.3 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX16640.1 - 0.058 13.6 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAX16640.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAX16640.1 - 0.14 11.2 0.5 0.21 10.6 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain BCDHK_Adom3 PF10436.9 GAX16642.1 - 5e-36 124.0 0.1 7.1e-36 123.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAX16642.1 - 4.7e-14 52.8 0.0 9.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX16642.1 - 6.3e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GWT1 PF06423.12 GAX16643.1 - 9.8e-18 64.7 8.5 9.8e-18 64.7 8.5 3.0 3 1 0 3 3 3 1 GWT1 DUF5080 PF16883.5 GAX16643.1 - 0.047 13.8 0.8 0.047 13.8 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5080) DUF3094 PF11293.8 GAX16643.1 - 0.27 11.0 0.2 0.27 11.0 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3094) Pox_A14 PF05767.12 GAX16643.1 - 2.4 8.4 7.8 0.15 12.3 0.4 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 HAD_SAK_2 PF18143.1 GAX16644.1 - 2.3e-24 86.3 0.0 2.7e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins PUB PF09409.10 GAX16646.1 - 1.4e-07 31.3 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 PUB domain PDZ PF00595.24 GAX16646.1 - 0.00091 19.5 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX16646.1 - 0.0017 18.2 0.2 0.0078 16.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX16646.1 - 0.0066 16.7 0.1 0.017 15.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain BSD PF03909.17 GAX16647.1 - 7.9e-12 45.0 0.3 7.9e-12 45.0 0.3 3.8 4 0 0 4 4 4 1 BSD domain Bacillus_HBL PF05791.11 GAX16647.1 - 0.003 17.4 9.0 0.003 17.4 9.0 3.6 3 0 0 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) Herpes_TAF50 PF03326.13 GAX16647.1 - 0.19 10.3 9.5 0.044 12.4 5.8 1.7 1 1 1 2 2 2 0 Herpesvirus transcription activation factor (transactivator) DUF4686 PF15742.5 GAX16647.1 - 0.58 9.2 49.6 0.18 10.9 10.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) Fez1 PF06818.15 GAX16647.1 - 1.2 9.6 51.0 0.041 14.3 28.8 3.1 2 1 1 3 3 3 0 Fez1 MitMem_reg PF13012.6 GAX16647.1 - 1.2 9.5 8.6 5.3 7.5 7.4 2.7 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Laminin_II PF06009.12 GAX16647.1 - 2.6 8.1 33.2 0.076 13.0 5.2 3.6 2 1 1 3 3 3 0 Laminin Domain II IL31 PF15209.6 GAX16647.1 - 3.7 7.3 8.2 0.26 11.1 1.5 2.5 2 1 0 2 2 2 0 Interleukin 31 WEMBL PF05701.11 GAX16647.1 - 9.4 4.8 47.0 6.1e+02 -1.2 47.5 2.2 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ARS2 PF04959.13 GAX16649.1 - 0.25 11.7 5.6 1.3 9.3 1.5 2.2 2 0 0 2 2 2 0 Arsenite-resistance protein 2 UCH PF00443.29 GAX16650.1 - 4e-37 128.1 0.0 6.6e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX16650.1 - 1.4e-12 47.8 0.0 2.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-H2C2_2 PF13465.6 GAX16650.1 - 0.65 10.5 2.7 35 5.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain eIF-3_zeta PF05091.12 GAX16651.1 - 7.4e-164 546.6 0.0 8.4e-164 546.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 GAX16651.1 - 0.046 13.2 0.3 0.18 11.3 0.0 2.2 3 0 0 3 3 3 0 NMDA receptor-regulated gene protein 2 C-terminus K-cyclin_vir_C PF09080.10 GAX16652.1 - 0.086 13.3 2.0 0.11 12.9 2.0 1.1 1 0 0 1 1 1 0 K cyclin, C terminal HATPase_c PF02518.26 GAX16654.1 - 0.00075 20.0 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioredoxin PF00085.20 GAX16655.1 - 2.1e-07 30.9 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAX16655.1 - 0.0097 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family SpecificRecomb PF10136.9 GAX16655.1 - 0.025 12.9 0.0 0.038 12.3 0.0 1.2 1 0 0 1 1 1 0 Site-specific recombinase NAD_binding_7 PF13241.6 GAX16655.1 - 0.036 14.5 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 GAX16655.1 - 0.039 14.4 0.0 0.069 13.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Glyco_trans_4_4 PF13579.6 GAX16655.1 - 0.04 14.4 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Pyr_redox PF00070.27 GAX16655.1 - 0.044 14.3 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1686 PF07937.11 GAX16655.1 - 0.19 11.6 0.1 0.3 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) Chloroa_b-bind PF00504.21 GAX16656.1 - 3.8e-35 121.8 0.1 6.5e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Cullin PF00888.22 GAX16657.1 - 2.2e-193 644.3 7.4 2.6e-193 644.0 7.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAX16657.1 - 4.3e-28 97.1 1.3 1.2e-27 95.7 0.7 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain CAF1 PF04857.20 GAX16658.1 - 1.5e-74 251.1 0.0 1.9e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease R3H PF01424.22 GAX16658.1 - 0.014 15.4 0.0 0.072 13.1 0.0 2.3 1 0 0 1 1 1 0 R3H domain TPR_12 PF13424.6 GAX16659.1 - 5.8e-21 74.6 0.8 1.1e-09 38.5 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX16659.1 - 6.4e-16 57.7 0.4 3.9e-05 23.4 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16659.1 - 7e-09 35.1 2.6 0.055 13.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16659.1 - 7.2e-09 35.1 3.0 0.11 12.7 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX16659.1 - 2.1e-08 33.6 0.4 0.12 12.5 0.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16659.1 - 8.1e-08 31.8 0.5 0.021 14.5 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 GAX16659.1 - 0.00032 20.7 2.6 1.4 9.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Osteoregulin PF07175.11 GAX16659.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.7 2 1 0 2 2 2 0 Osteoregulin TPR_MalT PF17874.1 GAX16659.1 - 0.12 11.8 0.0 0.12 11.8 0.0 2.8 2 1 2 4 4 4 0 MalT-like TPR region TPR_14 PF13428.6 GAX16659.1 - 0.24 12.3 7.5 13 6.9 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 GAX16660.1 - 3.1e-07 30.1 1.8 5.9e-06 25.9 1.8 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX16660.1 - 0.00047 20.2 1.3 0.0011 19.0 1.3 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily HAD_2 PF13419.6 GAX16661.1 - 1.1e-07 32.1 0.0 2.4e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 GAX16661.1 - 0.042 13.6 0.1 8 6.1 0.0 2.3 1 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Hydrolase_3 PF08282.12 GAX16661.1 - 0.043 13.5 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX16661.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1499 PF07386.11 GAX16662.1 - 7e-05 23.4 0.0 0.0001 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) BCDHK_Adom3 PF10436.9 GAX16664.1 - 8.8e-28 97.2 0.0 1.3e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAX16664.1 - 5.5e-11 43.0 0.0 9.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX16664.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAX16664.1 - 0.0014 18.6 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PDZ PF00595.24 GAX16665.1 - 2.9e-05 24.3 0.0 5.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX16665.1 - 0.003 17.8 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX16665.1 - 0.02 14.8 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Anoctamin PF04547.12 GAX16666.1 - 5.5e-103 345.2 5.5 7e-103 344.9 5.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PIG-H PF10181.9 GAX16666.1 - 0.11 12.4 0.3 0.33 10.9 0.3 1.9 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component zf-RING_2 PF13639.6 GAX16667.1 - 1.6e-12 47.6 5.3 1.6e-12 47.6 5.3 3.4 3 1 1 4 4 3 1 Ring finger domain zf-RING_11 PF17123.5 GAX16667.1 - 4.3e-11 42.4 1.9 4.3e-11 42.4 1.9 2.8 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX16667.1 - 3.6e-09 36.3 5.4 3.6e-09 36.3 5.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX16667.1 - 1.6e-08 34.3 4.1 1.6e-08 34.3 4.1 2.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX16667.1 - 3e-06 27.1 2.9 3e-06 27.1 2.9 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAX16667.1 - 3.4e-06 27.3 6.3 3.4e-06 27.3 6.3 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RanBP PF00641.18 GAX16667.1 - 2.3e-05 23.6 1.9 2.3e-05 23.6 1.9 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_3 PF13920.6 GAX16667.1 - 4.8e-05 23.1 2.9 4.8e-05 23.1 2.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX16667.1 - 0.00021 21.2 3.4 0.00021 21.2 3.4 2.7 3 0 0 3 3 3 1 zinc-RING finger domain DUF5518 PF17647.1 GAX16667.1 - 0.0009 19.4 1.7 0.0015 18.7 1.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5518) Prok-RING_4 PF14447.6 GAX16667.1 - 0.012 15.5 3.9 0.012 15.5 3.9 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX16667.1 - 0.025 14.6 2.1 0.025 14.6 2.1 2.0 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Gly-zipper_YMGG PF13441.6 GAX16667.1 - 0.08 12.7 7.0 0.15 11.8 7.0 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 GAX16667.1 - 0.1 12.6 7.7 0.2 11.7 7.7 1.4 1 0 0 1 1 1 0 Glycine zipper zf-RING-like PF08746.11 GAX16667.1 - 0.23 11.8 8.6 0.082 13.2 3.4 2.5 2 0 0 2 2 2 0 RING-like domain DNA_RNApol_7kD PF03604.13 GAX16667.1 - 0.29 10.8 0.1 0.29 10.8 0.1 2.1 2 0 0 2 2 1 0 DNA directed RNA polymerase, 7 kDa subunit RINGv PF12906.7 GAX16667.1 - 1.3 9.2 7.8 1.7 8.8 4.3 2.6 2 1 0 2 2 2 0 RING-variant domain OrfB_Zn_ribbon PF07282.11 GAX16667.1 - 1.4 8.9 5.3 3.5 7.6 0.7 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain FYDLN_acid PF09538.10 GAX16667.1 - 1.4 9.6 5.5 3.8 8.2 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FANCL_C PF11793.8 GAX16667.1 - 4 7.7 8.8 4.2 7.6 5.2 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain DZR PF12773.7 GAX16667.1 - 7.9 6.6 12.0 9.8 6.3 1.0 3.4 3 1 0 3 3 3 0 Double zinc ribbon Rick_17kDa_Anti PF05433.15 GAX16667.1 - 9 6.2 10.2 24 4.9 10.2 1.7 1 1 0 1 1 1 0 Glycine zipper 2TM domain DSHCT PF08148.12 GAX16668.1 - 6.3e-55 185.3 0.6 1.3e-54 184.2 0.6 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 GAX16668.1 - 1.3e-23 84.3 0.0 4.2e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 GAX16668.1 - 1.7e-18 67.0 0.1 3.9e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX16668.1 - 5.2e-06 26.8 0.0 3.5e-05 24.1 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAX16668.1 - 0.0014 18.9 0.1 0.099 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Ski2_N PF17911.1 GAX16668.1 - 0.016 15.0 0.1 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 Ski2 N-terminal region YL1 PF05764.13 GAX16668.1 - 0.065 13.4 7.9 0.19 11.8 7.9 1.8 1 0 0 1 1 1 0 YL1 nuclear protein RNA_pol_Rpb5_C PF01191.19 GAX16668.1 - 0.12 12.2 0.0 0.51 10.2 0.0 2.1 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain PhoH PF02562.16 GAX16668.1 - 0.15 11.5 0.1 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein SprA-related PF12118.8 GAX16668.1 - 0.43 9.7 3.9 0.72 8.9 3.9 1.3 1 0 0 1 1 1 0 SprA-related family DUF1770 PF08589.10 GAX16668.1 - 0.44 11.5 2.7 1.6 9.7 2.7 2.0 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Sporozoite_P67 PF05642.11 GAX16668.1 - 6.7 4.7 7.4 9.7 4.1 6.9 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Myb_DNA-binding PF00249.31 GAX16671.1 - 1.3e-19 70.1 0.6 2.8e-12 46.6 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX16671.1 - 2.3e-15 56.6 0.5 1e-09 38.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX16671.1 - 3.6e-05 23.6 0.1 0.042 13.7 0.0 2.3 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 GAX16671.1 - 0.03 14.7 8.1 0.38 11.2 0.1 3.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain LBR_tudor PF09465.10 GAX16671.1 - 0.045 13.6 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain MAPEG PF01124.18 GAX16673.1 - 8.6e-05 22.5 0.2 0.00016 21.6 0.2 1.5 1 1 0 1 1 1 1 MAPEG family EMC3_TMCO1 PF01956.16 GAX16673.1 - 0.025 14.3 0.7 0.031 14.0 0.7 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Cellulase PF00150.18 GAX16674.1 - 2.5e-33 115.7 4.2 4.2e-33 115.0 4.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_6 PF03422.15 GAX16674.1 - 2.6e-25 89.1 0.2 7.6e-17 61.8 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX16674.1 - 1.2e-09 38.3 0.3 1.7e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 DUF5010 C-terminal domain MBOAT PF03062.19 GAX16675.1 - 1.5e-26 93.6 30.4 2.4e-26 92.9 30.4 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PH PF00169.29 GAX16675.1 - 6.9e-08 32.9 0.0 1.9e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 PH domain MBOAT_2 PF13813.6 GAX16675.1 - 0.0066 16.7 8.8 0.02 15.2 8.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PH_11 PF15413.6 GAX16675.1 - 0.0077 16.6 0.0 0.052 14.0 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain DUF4200 PF13863.6 GAX16675.1 - 0.055 13.9 0.3 0.13 12.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PH_13 PF16652.5 GAX16675.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Chlam_OMP6 PF03504.13 GAX16677.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 NUDIX PF00293.28 GAX16678.1 - 7.5e-17 61.6 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 GAX16678.1 - 0.0001 21.9 0.1 0.0006 19.4 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4916) SET PF00856.28 GAX16679.1 - 5.1e-15 56.3 0.0 1.5e-14 54.7 0.0 1.8 1 1 0 1 1 1 1 SET domain RPN7 PF10602.9 GAX16679.1 - 0.12 12.0 0.1 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 26S proteasome subunit RPN7 MFS_1 PF07690.16 GAX16680.1 - 1.2e-45 156.0 26.0 1e-44 153.0 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAX16680.1 - 6.6e-05 21.4 1.9 0.084 11.1 0.7 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family EamA PF00892.20 GAX16681.1 - 1.2e-22 80.5 37.1 1.2e-13 51.4 12.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAX16681.1 - 0.00085 18.6 0.1 0.0019 17.4 0.1 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF2371 PF10177.9 GAX16681.1 - 0.032 14.4 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF4815 PF16075.5 GAX16681.1 - 0.09 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) TPT PF03151.16 GAX16681.1 - 0.12 11.7 7.6 0.64 9.3 0.3 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2583 PF10762.9 GAX16681.1 - 0.12 12.8 0.2 0.12 12.8 0.2 3.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2583) CAP_N PF01213.19 GAX16682.1 - 5.9e-47 160.7 0.0 9.2e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 GAX16682.1 - 1.1e-45 155.1 5.2 1.7e-45 154.4 5.2 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 GAX16682.1 - 0.0073 16.0 3.5 0.013 15.3 3.5 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Peptidase_M17 PF00883.21 GAX16683.1 - 3.1e-98 328.9 0.5 4e-98 328.5 0.5 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 GAX16683.1 - 7.8e-10 39.1 1.6 1.6e-09 38.1 0.2 2.2 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 PAS_4 PF08448.10 GAX16683.1 - 0.099 12.9 0.2 0.44 10.8 0.2 2.0 1 1 0 1 1 1 0 PAS fold NTP_transferase PF00483.23 GAX16683.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase DUF2214 PF09980.9 GAX16684.1 - 2.1e-43 147.7 0.6 8.9e-43 145.6 0.3 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2214) Tetraspanin PF00335.20 GAX16684.1 - 4.3 7.0 4.8 1.2 8.8 1.6 1.7 2 0 0 2 2 2 0 Tetraspanin family TPR_12 PF13424.6 GAX16685.1 - 1.3e-94 310.5 38.3 1.1e-16 60.8 0.2 9.8 5 3 5 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 GAX16685.1 - 1.4e-81 266.4 52.3 9.8e-10 38.0 0.1 15.1 15 1 0 15 15 15 13 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16685.1 - 1.2e-58 192.6 23.3 4.2e-05 23.2 0.0 15.2 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16685.1 - 1.4e-49 162.3 28.0 6.4e-05 22.8 0.1 15.1 15 2 1 16 16 16 10 Tetratricopeptide repeat TPR_7 PF13176.6 GAX16685.1 - 9.9e-44 144.2 32.5 0.00035 20.4 0.0 14.2 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_8 PF13181.6 GAX16685.1 - 6.6e-40 132.0 17.2 0.001 19.1 0.0 14.5 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_16 PF13432.6 GAX16685.1 - 8.6e-26 90.3 19.8 0.003 18.2 0.1 11.9 9 3 2 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.6 GAX16685.1 - 1.4e-25 88.7 13.9 0.0007 19.2 0.1 12.6 12 1 1 13 13 12 5 TPR repeat TPR_MalT PF17874.1 GAX16685.1 - 4.7e-24 85.4 26.6 4.1e-11 42.8 1.8 5.6 3 2 3 6 6 6 5 MalT-like TPR region TPR_6 PF13174.6 GAX16685.1 - 1.3e-18 66.3 17.6 0.88 10.4 0.0 13.5 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX16685.1 - 2e-18 65.5 32.3 0.48 11.4 0.0 13.2 13 1 1 14 14 13 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAX16685.1 - 1.4e-11 43.9 4.4 2.9 8.5 0.0 9.4 10 0 0 10 10 8 1 Tetratricopeptide repeat MIT PF04212.18 GAX16685.1 - 2.2e-11 43.6 17.4 1.2 9.3 0.0 10.5 11 0 0 11 11 11 2 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 GAX16685.1 - 8.6e-08 32.6 19.7 0.017 15.6 0.0 8.3 8 2 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX16685.1 - 6.5e-07 29.4 0.0 16 6.5 0.1 8.0 8 0 0 8 8 7 0 Tetratricopeptide repeat SNAP PF14938.6 GAX16685.1 - 9e-07 28.6 7.4 0.0051 16.3 0.0 5.2 4 2 0 5 5 5 1 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 GAX16685.1 - 1.4e-06 27.7 12.4 4.1 6.5 0.0 8.6 8 1 3 11 11 11 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX16685.1 - 4e-06 26.7 2.4 0.15 11.8 0.0 5.2 2 1 3 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 GAX16685.1 - 1.2e-05 25.3 11.3 4 7.7 0.2 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX16685.1 - 1.4e-05 25.2 12.8 2 8.7 0.0 8.3 3 3 4 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 GAX16685.1 - 0.00029 20.6 15.4 4.1 7.1 0.0 7.9 4 4 4 10 10 10 1 26S proteasome subunit RPN7 ANAPC5 PF12862.7 GAX16685.1 - 0.00078 19.5 17.1 1 9.5 0.0 8.5 6 2 1 9 9 8 1 Anaphase-promoting complex subunit 5 TPR_5 PF12688.7 GAX16685.1 - 0.0077 16.5 11.4 0.81 9.9 0.0 5.7 4 2 0 5 5 5 1 Tetratrico peptide repeat PPR PF01535.20 GAX16685.1 - 0.011 16.0 3.3 23 5.5 0.0 7.0 9 0 0 9 9 6 0 PPR repeat DUF627 PF04781.12 GAX16685.1 - 0.023 14.7 10.9 0.55 10.3 0.2 5.7 6 1 0 7 7 6 0 Protein of unknown function (DUF627) Glyoxalase PF00903.25 GAX16685.1 - 0.06 13.5 0.4 9.5 6.4 0.0 3.6 3 2 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TTRAP PF14203.6 GAX16685.1 - 0.12 12.4 1.0 2.8 8.0 0.0 3.3 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein SHNi-TPR PF10516.9 GAX16685.1 - 0.22 11.0 10.6 24 4.5 0.0 6.5 8 0 0 8 8 8 0 SHNi-TPR PPR_2 PF13041.6 GAX16685.1 - 0.78 10.0 2.4 48 4.2 0.0 4.8 6 0 0 6 6 4 0 PPR repeat family DUF3856 PF12968.7 GAX16685.1 - 2.5 8.1 8.1 40 4.3 0.0 5.7 5 4 0 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 GAX16685.1 - 2.6 8.1 17.6 3.4 7.8 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Glyco_hydro_2_C PF02836.17 GAX16686.1 - 1e-84 284.2 0.0 1.4e-84 283.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 GAX16686.1 - 6.8e-62 209.2 0.0 1.2e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 GAX16686.1 - 2.2e-38 131.8 0.1 5.7e-38 130.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 GAX16686.1 - 8.1e-12 45.5 0.0 7.4e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 GAX16686.1 - 1.1e-08 35.8 0.0 2.9e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 APG9 PF04109.16 GAX16687.1 - 2.5e-132 442.3 0.0 3e-132 442.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Mtc PF03820.17 GAX16688.1 - 7.1e-92 307.8 0.0 1e-91 307.3 0.0 1.2 1 0 0 1 1 1 1 Tricarboxylate carrier Apolipoprotein PF01442.18 GAX16689.1 - 0.017 15.0 0.3 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ocnus PF05005.15 GAX16692.1 - 1.5e-15 57.3 0.0 3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) PseudoU_synth_2 PF00849.22 GAX16692.1 - 7.1e-13 48.9 0.1 3.6e-12 46.7 0.1 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_M44 PF03410.13 GAX16692.1 - 0.019 13.5 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox Gelsolin PF00626.22 GAX16693.1 - 5.5e-14 51.8 0.2 7.2e-05 22.6 0.0 4.1 4 0 0 4 4 4 3 Gelsolin repeat Exo_endo_phos PF03372.23 GAX16694.1 - 7e-22 78.1 0.0 3.8e-21 75.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAX16694.1 - 0.11 12.3 3.1 0.12 12.2 0.1 2.6 3 1 0 3 3 3 0 Endonuclease-reverse transcriptase HSP70 PF00012.20 GAX16695.1 - 6.2e-257 853.6 14.4 7e-257 853.4 14.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX16695.1 - 5.8e-19 68.1 1.8 7.6e-18 64.4 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAX16695.1 - 0.00018 21.3 0.0 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4624 PF15417.6 GAX16695.1 - 0.0055 16.5 0.1 2 8.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4624) Hydantoinase_A PF01968.18 GAX16695.1 - 0.01 15.1 1.6 0.046 13.0 0.2 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.6 GAX16695.1 - 0.018 15.5 5.0 1.4 9.4 1.7 3.6 2 1 0 2 2 2 0 Cell division protein FtsA DDR PF08841.10 GAX16695.1 - 0.066 12.2 2.9 0.45 9.5 0.3 2.6 2 1 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain ParcG PF10274.9 GAX16695.1 - 0.21 11.7 0.5 1 9.5 0.1 2.1 2 0 0 2 2 2 0 Parkin co-regulated protein HU-CCDC81_bac_2 PF18175.1 GAX16695.1 - 0.52 10.2 3.9 1.4 8.8 0.4 3.0 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 zf-C4H2 PF10146.9 GAX16695.1 - 0.55 10.5 3.0 5.7 7.2 1.2 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein Spectrin PF00435.21 GAX16695.1 - 2.9 8.4 13.5 0.2 12.1 1.1 3.3 2 1 1 3 3 3 0 Spectrin repeat MutS_III PF05192.18 GAX16695.1 - 4.6 7.4 6.8 2 8.6 0.8 2.3 2 1 0 2 2 2 0 MutS domain III bZIP_1 PF00170.21 GAX16696.1 - 0.0009 19.3 9.6 0.0009 19.3 9.6 2.1 2 1 0 2 2 2 1 bZIP transcription factor GvpL_GvpF PF06386.11 GAX16696.1 - 0.0083 16.1 4.5 0.011 15.7 4.5 1.1 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF TSC22 PF01166.18 GAX16696.1 - 0.017 15.4 3.8 0.043 14.1 3.8 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Atg14 PF10186.9 GAX16696.1 - 0.11 11.5 9.1 0.15 11.2 9.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ndc1_Nup PF09531.10 GAX16696.1 - 0.37 9.4 6.4 0.38 9.4 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HAUS6_N PF14661.6 GAX16696.1 - 0.76 9.3 11.1 1.1 8.8 11.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus bZIP_2 PF07716.15 GAX16696.1 - 0.88 9.7 20.6 0.11 12.6 10.6 3.2 1 1 2 3 3 3 0 Basic region leucine zipper V_ATPase_I PF01496.19 GAX16696.1 - 1.3 6.9 5.9 1.6 6.6 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.6 GAX16696.1 - 7.4 7.1 11.7 9.7 6.7 11.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DpnI PF06044.12 GAX16697.1 - 0.069 12.8 0.3 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Dam-replacing family Peptidase_M16_M PF16187.5 GAX16698.1 - 3.1e-68 230.1 0.3 4.9e-68 229.4 0.3 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX16698.1 - 5.1e-32 110.9 0.1 9.4e-32 110.0 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX16698.1 - 1.7e-29 103.1 0.1 3e-20 73.0 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain Pkinase PF00069.25 GAX16699.1 - 4e-40 137.8 0.0 5.7e-20 71.8 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16699.1 - 2.1e-12 46.9 0.0 2.3e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAX16699.1 - 0.055 12.8 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GAX16699.1 - 0.29 9.8 5.2 0.043 12.6 0.3 2.1 2 1 0 2 2 2 0 Fungal protein kinase MS_channel PF00924.18 GAX16700.1 - 4.3e-22 78.7 0.1 7e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel DEAD PF00270.29 GAX16701.1 - 4.7e-39 134.0 0.0 9.2e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX16701.1 - 1.1e-28 99.8 0.5 3.1e-25 88.7 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAX16701.1 - 4.9e-08 33.2 0.0 8.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAX16701.1 - 0.0013 18.2 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 GAX16701.1 - 0.0073 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Oxidored_FMN PF00724.20 GAX16702.1 - 3.1e-70 237.1 0.0 5.8e-69 233.0 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 GAX16702.1 - 4.4e-24 85.2 0.0 7.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX16702.1 - 2.9e-09 37.0 0.0 1.4e-08 34.9 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAX16702.1 - 5.9e-08 32.3 2.0 0.001 18.4 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX16702.1 - 7e-08 32.2 0.2 5.2e-07 29.4 0.1 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX16702.1 - 3.5e-07 30.7 0.8 0.001 19.6 0.1 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX16702.1 - 2.6e-06 26.4 0.1 7.3e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAX16702.1 - 1.6e-05 24.2 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAX16702.1 - 3.2e-05 23.2 0.1 7.2e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 GAX16702.1 - 5.7e-05 23.1 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 GAX16702.1 - 0.0006 19.5 0.0 0.0006 19.5 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAX16702.1 - 0.00065 18.9 0.0 0.12 11.5 0.0 3.3 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.23 GAX16702.1 - 0.0018 18.3 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 GAX16702.1 - 0.0057 16.0 0.0 1.7 7.9 0.0 2.6 2 0 0 2 2 2 1 ThiF family UDPG_MGDP_dh_N PF03721.14 GAX16702.1 - 0.015 14.9 0.2 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 GAX16702.1 - 0.038 13.6 0.2 0.71 9.5 0.0 2.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 GAX16702.1 - 0.049 14.2 0.1 68 4.1 0.1 3.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 GAX16702.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GAX16702.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.9 3 0 0 3 3 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.23 GAX16702.1 - 0.17 12.0 0.4 56 3.8 0.0 3.3 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain ABC1 PF03109.16 GAX16704.1 - 2.5e-14 53.5 0.0 5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GAX16704.1 - 0.054 12.9 0.1 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Aminotran_1_2 PF00155.21 GAX16705.1 - 1.1e-83 281.4 0.0 1.3e-83 281.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ILEI PF15711.5 GAX16705.1 - 0.017 15.6 0.0 0.062 13.8 0.0 1.8 2 0 0 2 2 2 0 Interleukin-like EMT inducer CbiA PF01656.23 GAX16706.1 - 0.0079 16.3 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain LpxK PF02606.14 GAX16706.1 - 0.012 14.7 0.1 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase UPF0004 PF00919.20 GAX16706.1 - 0.034 14.2 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 ParA PF10609.9 GAX16706.1 - 0.059 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase MarR_2 PF12802.7 GAX16706.1 - 0.2 11.6 0.1 3 7.8 0.0 2.6 3 0 0 3 3 3 0 MarR family AA_kinase PF00696.28 GAX16707.1 - 2.3e-17 63.4 0.0 7.8e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Amino acid kinase family Methyltransf_11 PF08241.12 GAX16708.1 - 2.8e-12 47.1 0.0 4.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX16708.1 - 4.9e-10 39.5 0.0 7.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX16708.1 - 5.1e-10 39.9 0.0 9.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX16708.1 - 7.4e-09 35.6 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX16708.1 - 2.1e-07 30.5 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX16708.1 - 0.00044 21.0 0.0 0.00078 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Patatin PF01734.22 GAX16709.1 - 1.6e-12 48.0 0.2 6e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase PseudoU_synth_2 PF00849.22 GAX16710.1 - 2.3e-14 53.8 0.0 3.3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Chorismate_bind PF00425.18 GAX16711.1 - 1.1e-85 287.3 0.0 1.8e-85 286.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 GAX16711.1 - 1.6e-37 129.1 0.0 2.8e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAX16711.1 - 3.4e-10 40.3 0.0 7.3e-09 36.0 0.0 2.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAX16711.1 - 2.2e-08 34.1 0.1 6.8e-08 32.5 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 LytTR PF04397.15 GAX16711.1 - 0.0037 17.5 0.0 0.0084 16.3 0.0 1.6 1 0 0 1 1 1 1 LytTr DNA-binding domain DUF4315 PF14193.6 GAX16711.1 - 0.27 11.2 1.1 0.64 10.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) ubiquitin PF00240.23 GAX16712.1 - 0.00012 21.7 0.0 0.0004 20.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 GAX16712.1 - 0.0081 16.3 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Bmt2 PF11968.8 GAX16713.1 - 1.1e-41 143.1 0.0 1.5e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_8 PF05148.15 GAX16713.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 GAX16713.1 - 0.0067 16.3 0.0 0.074 12.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FAA_hydrolase PF01557.18 GAX16714.1 - 7.9e-44 149.9 0.0 1.1e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family zf-MYND PF01753.18 GAX16714.1 - 4.3e-07 29.9 16.6 4.3e-07 29.9 16.6 2.2 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 GAX16714.1 - 0.087 13.1 9.0 0.34 11.3 9.0 2.0 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TFIIE_alpha PF02002.17 GAX16715.1 - 3.4e-11 42.9 0.4 1.1e-10 41.3 0.4 1.9 1 0 0 1 1 1 1 TFIIE alpha subunit Rpp20 PF12328.8 GAX16715.1 - 5 7.1 9.7 2.5 8.0 2.6 2.7 3 0 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P UBA PF00627.31 GAX16716.1 - 1.2e-11 44.3 0.5 4.9e-11 42.3 0.5 2.2 2 0 0 2 2 2 1 UBA/TS-N domain PUB PF09409.10 GAX16716.1 - 5e-09 36.0 0.0 1.9e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 PUB domain UBX PF00789.20 GAX16716.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain RAP80_UIM PF18282.1 GAX16716.1 - 0.014 15.1 1.5 0.025 14.3 0.2 2.1 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 GAX16716.1 - 0.023 14.6 2.0 0.023 14.6 2.0 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif UBA_4 PF14555.6 GAX16716.1 - 0.059 13.2 0.3 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 UBA-like domain HTH_8 PF02954.19 GAX16716.1 - 1.2 9.0 4.4 0.39 10.5 0.7 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family DAGAT PF03982.13 GAX16717.1 - 4.3e-37 127.6 0.0 5.5e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GAX16717.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Isochorismatase PF00857.20 GAX16718.1 - 7.5e-08 32.7 0.2 0.0028 17.8 0.0 2.6 3 0 0 3 3 3 2 Isochorismatase family Ribosomal_L28 PF00830.19 GAX16719.1 - 2.3e-18 66.1 0.0 3.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L28 family CN_hydrolase PF00795.22 GAX16720.1 - 0.025 13.9 0.0 0.073 12.4 0.0 1.7 1 1 1 2 2 2 0 Carbon-nitrogen hydrolase Metallophos PF00149.28 GAX16722.1 - 6.2e-06 26.9 1.2 9.4e-06 26.3 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4366 PF14283.6 GAX16722.1 - 0.0091 16.1 0.0 0.023 14.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) Sortase PF04203.13 GAX16722.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Sortase domain Orf78 PF06024.12 GAX16722.1 - 0.086 13.2 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_S49 PF01343.18 GAX16723.1 - 9e-29 100.4 0.0 1.7e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 GAX16723.1 - 0.00094 19.3 1.8 0.093 12.8 0.1 2.5 2 1 0 2 2 2 2 Peptidase family S49 N-terminal MIF4G_like PF09088.11 GAX16725.1 - 6.8e-08 32.5 0.2 1.3e-07 31.6 0.2 1.3 1 0 0 1 1 1 1 MIF4G like DUF2894 PF11445.8 GAX16725.1 - 0.067 13.7 0.6 0.62 10.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) CENP-B_dimeris PF09026.10 GAX16725.1 - 3.2 8.2 9.2 30 5.1 0.1 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 GAX16725.1 - 3.5 7.9 13.4 6.9 7.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) SKA1 PF07160.12 GAX16727.1 - 2.3e-07 30.9 3.0 5.8e-07 29.6 2.7 1.7 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 zf-C4H2 PF10146.9 GAX16727.1 - 0.037 14.3 2.5 0.047 14.0 2.5 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein ApoLp-III PF07464.11 GAX16727.1 - 0.043 13.9 0.2 0.088 12.9 0.2 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Chal_sti_synt_N PF00195.19 GAX16727.1 - 0.058 12.8 0.2 0.083 12.3 0.2 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Spectrin PF00435.21 GAX16727.1 - 0.067 13.7 1.4 0.067 13.7 1.4 2.5 3 0 0 3 3 3 0 Spectrin repeat HNOB PF07700.15 GAX16727.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Haem-NO-binding G_glu_transpept PF01019.21 GAX16728.1 - 4.6e-118 395.2 0.0 5.3e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3510 PF12022.8 GAX16730.1 - 3.6e-32 111.4 0.1 1.1e-31 109.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) CorA PF01544.18 GAX16730.1 - 8.4 5.6 7.4 39 3.4 4.3 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein IPK PF03770.16 GAX16731.1 - 4.3e-36 124.6 0.0 2.1e-35 122.4 0.0 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase Pyr_redox_2 PF07992.14 GAX16732.1 - 2.6e-74 250.1 2.7 3.8e-74 249.6 2.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX16732.1 - 2.7e-43 146.7 0.4 1.3e-42 144.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX16732.1 - 5.7e-24 84.5 5.6 9.8e-21 74.1 0.4 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX16732.1 - 1.9e-09 37.2 3.0 5.2e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX16732.1 - 4.3e-08 32.9 4.3 4.3e-08 32.9 4.3 2.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX16732.1 - 5.5e-08 32.3 8.5 1.9e-05 23.9 2.0 3.5 3 1 1 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.6 GAX16732.1 - 1.6e-07 31.4 0.6 0.0003 20.9 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAX16732.1 - 2.6e-06 26.8 9.7 8e-06 25.2 3.9 3.1 2 2 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAX16732.1 - 9.5e-06 25.1 2.1 0.014 14.7 0.2 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAX16732.1 - 0.00016 21.0 0.5 0.0025 17.1 0.1 2.9 4 0 0 4 4 4 1 Thi4 family HI0933_like PF03486.14 GAX16732.1 - 0.00079 18.2 11.1 0.0027 16.5 1.3 3.6 3 1 1 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.18 GAX16732.1 - 0.0024 17.8 0.9 0.0042 17.0 0.2 1.8 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 GAX16732.1 - 0.0027 16.9 3.1 0.73 8.9 0.1 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 GAX16732.1 - 0.0057 15.9 8.9 0.11 11.7 1.2 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX16732.1 - 0.034 13.7 12.1 2.1 7.9 0.0 3.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX16732.1 - 0.16 11.0 1.3 1.6 7.7 0.6 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein RuBisCO_large PF00016.20 GAX16732.1 - 1.1 8.4 5.3 8.4 5.5 0.1 3.1 3 0 0 3 3 3 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DUF3801 PF12687.7 GAX16732.1 - 1.1 9.3 5.6 0.59 10.2 0.2 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF3801) NAD_binding_7 PF13241.6 GAX16732.1 - 1.4 9.4 3.3 5.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding SAPS PF04499.15 GAX16733.1 - 2.7e-05 23.1 4.0 2.7e-05 23.1 4.0 5.0 4 1 1 5 5 5 2 SIT4 phosphatase-associated protein CRT-like PF08627.10 GAX16734.1 - 1.1e-14 54.2 15.8 1e-11 44.4 6.1 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Cu-oxidase_2 PF07731.14 GAX16735.1 - 2.1e-14 53.5 3.0 2.1e-14 53.5 3.0 2.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAX16735.1 - 1.3e-08 34.9 0.0 5.3e-08 32.9 0.0 2.0 3 0 0 3 3 3 1 Multicopper oxidase MRP-L27 PF09809.9 GAX16736.1 - 3.2e-16 59.1 0.3 4.2e-16 58.8 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Rab5ip PF07019.12 GAX16737.1 - 0.00015 22.3 8.5 0.0002 21.9 8.5 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Ras PF00071.22 GAX16739.1 - 7.2e-64 214.3 0.3 8.6e-64 214.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX16739.1 - 6.2e-36 123.3 0.1 1.1e-35 122.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX16739.1 - 6.7e-16 58.2 0.1 8.4e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX16739.1 - 1.2e-06 28.5 0.1 4e-06 26.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX16739.1 - 2.3e-06 27.3 0.3 5.5e-06 26.1 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAX16739.1 - 2.4e-06 27.1 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAX16739.1 - 7e-05 22.8 0.2 0.065 13.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAX16739.1 - 7.3e-05 22.3 0.1 0.00013 21.5 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAX16739.1 - 0.006 16.1 0.0 0.076 12.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAX16739.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CENP-M PF11111.8 GAX16739.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_22 PF13401.6 GAX16739.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 GAX16739.1 - 0.041 13.1 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 GAX16739.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAX16739.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter RPN2_C PF18004.1 GAX16740.1 - 9.7e-35 119.8 9.5 1.5e-34 119.2 9.5 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 GAX16740.1 - 1e-23 82.5 20.0 4.6e-06 26.8 0.0 8.2 7 1 0 7 7 7 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAX16740.1 - 2.8e-16 59.7 7.1 9.5e-10 38.7 0.0 7.0 4 2 3 7 7 7 2 HEAT repeats HEAT PF02985.22 GAX16740.1 - 0.012 15.9 0.4 19 5.8 0.1 4.3 5 0 0 5 5 5 0 HEAT repeat TPR_5 PF12688.7 GAX16740.1 - 0.02 15.1 0.7 28 5.0 0.1 4.2 4 0 0 4 4 4 0 Tetratrico peptide repeat IBN_N PF03810.19 GAX16740.1 - 0.086 12.8 1.0 39 4.3 0.1 4.8 4 2 2 6 6 6 0 Importin-beta N-terminal domain HEAT_EZ PF13513.6 GAX16740.1 - 0.98 10.0 5.9 4.9 7.8 0.0 4.7 4 2 2 6 6 6 0 HEAT-like repeat DUF4685 PF15737.5 GAX16741.1 - 3.6 8.0 13.9 0.057 13.9 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) GAS PF13851.6 GAX16742.1 - 0.0056 16.1 5.5 0.013 14.9 5.5 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding KxDL PF10241.9 GAX16742.1 - 0.046 14.0 6.1 0.36 11.1 5.6 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Golgin_A5 PF09787.9 GAX16742.1 - 0.39 10.2 6.9 0.19 11.2 3.3 2.3 3 0 0 3 3 3 0 Golgin subfamily A member 5 ZapB PF06005.12 GAX16742.1 - 2.6 8.5 14.2 0.058 13.8 6.7 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 GAX16742.1 - 5.3 6.3 6.6 11 5.3 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 GAX16742.1 - 6.6 6.6 7.0 3.2 7.6 3.7 2.1 1 1 1 2 2 2 0 Septum formation initiator HOOK PF05622.12 GAX16742.1 - 9.1 4.3 15.3 0.71 8.0 8.3 2.0 2 0 0 2 2 2 0 HOOK protein HSF_DNA-bind PF00447.17 GAX16744.1 - 4.9e-19 68.7 0.0 9.7e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Exo_endo_phos PF03372.23 GAX16745.1 - 1.3e-06 28.1 0.0 1.6e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family AAA PF00004.29 GAX16746.1 - 3.1e-25 89.1 0.0 9.4e-25 87.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX16746.1 - 8e-06 26.3 0.6 0.00026 21.4 0.1 3.0 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAX16746.1 - 1.9e-05 25.0 0.6 0.004 17.4 0.0 3.6 2 1 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 GAX16746.1 - 4.9e-05 22.8 0.1 9.1e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX16746.1 - 8.4e-05 22.8 0.0 0.00042 20.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAX16746.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 GAX16746.1 - 0.0016 18.4 0.2 0.0065 16.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX16746.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 GAX16746.1 - 0.0031 17.4 0.0 0.034 14.1 0.0 2.3 1 1 1 2 2 2 1 RsgA GTPase AAA_lid_3 PF17862.1 GAX16746.1 - 0.0033 17.2 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 GAX16746.1 - 0.0062 16.1 0.0 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 GAX16746.1 - 0.007 15.8 0.0 0.74 9.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 GAX16746.1 - 0.0091 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 GAX16746.1 - 0.013 15.4 0.3 0.19 11.6 0.0 2.6 1 1 1 2 2 2 0 NACHT domain CAF1A PF12253.8 GAX16746.1 - 0.02 15.0 1.2 0.02 15.0 1.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Viral_helicase1 PF01443.18 GAX16746.1 - 0.042 13.6 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 GAX16746.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 GAX16746.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_17 PF13207.6 GAX16746.1 - 0.1 13.1 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAX16746.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAX16746.1 - 0.18 12.3 0.0 0.49 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAX16746.1 - 0.2 11.6 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ank_5 PF13857.6 GAX16747.1 - 0.00019 21.6 0.6 1.7 9.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX16747.1 - 0.14 12.8 1.5 94 4.1 0.1 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 GAX16747.1 - 0.74 10.4 3.4 1.4e+02 3.2 0.0 4.0 3 1 0 3 3 3 0 Ankyrin repeat Dicty_CAD PF05720.12 GAX16748.1 - 0.069 13.1 0.3 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Cell-cell adhesion domain TBCA PF02970.16 GAX16749.1 - 5.9e-27 93.8 4.7 7.5e-27 93.5 4.7 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A EnY2 PF10163.9 GAX16749.1 - 0.008 16.5 0.5 0.028 14.8 0.1 2.0 1 1 1 2 2 2 1 Transcription factor e(y)2 DUF948 PF06103.11 GAX16749.1 - 0.044 14.1 0.5 6.8 7.0 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CotJB PF12652.7 GAX16749.1 - 0.11 12.7 2.5 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 CotJB protein Fib_alpha PF08702.10 GAX16749.1 - 0.11 12.7 5.0 3.6 7.8 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 GAX16749.1 - 0.25 10.5 3.4 0.29 10.4 3.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF3336 PF11815.8 GAX16751.1 - 8.7e-22 77.3 4.6 2.3e-21 75.9 4.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAX16751.1 - 1.4e-21 77.7 0.0 3.1e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Aa_trans PF01490.18 GAX16752.1 - 3.5e-45 154.5 27.6 4.7e-45 154.0 27.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1129 PF06570.11 GAX16752.1 - 2.5 7.5 6.5 9.8 5.6 0.1 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) Methyltransf_23 PF13489.6 GAX16753.1 - 1.1e-08 35.1 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX16753.1 - 3.3e-07 30.9 0.0 6.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX16753.1 - 3.2e-06 27.0 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX16753.1 - 5.9e-06 27.0 0.0 9.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX16753.1 - 4.2e-05 24.1 0.0 0.00011 22.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX16753.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX16753.1 - 0.00015 21.4 0.0 0.00032 20.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 GAX16753.1 - 0.0032 16.8 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_17 PF12692.7 GAX16753.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase PrmA PF06325.13 GAX16753.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 GAX16753.1 - 0.22 10.6 0.0 0.49 9.4 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Glyoxalase_6 PF18029.1 GAX16754.1 - 3.8e-05 24.4 0.0 4.8e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 GAX16754.1 - 0.00017 21.8 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5_nucleotid_C PF02872.18 GAX16755.1 - 1.2e-22 80.9 0.0 1.5e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Lum_binding PF00677.17 GAX16756.1 - 7.6e-44 147.6 0.2 1.4e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ABC_tran_CTD PF16326.5 GAX16756.1 - 0.097 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain LSM PF01423.22 GAX16757.1 - 3.5e-17 61.9 0.1 4.6e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX16757.1 - 0.016 15.3 0.3 0.022 14.9 0.3 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 GAX16757.1 - 0.027 14.3 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BPL_C PF02237.17 GAX16757.1 - 0.027 14.3 0.9 0.049 13.5 0.9 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Hfq PF17209.3 GAX16757.1 - 0.047 13.3 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 Hfq protein RsfS PF02410.15 GAX16758.1 - 1.1e-20 73.9 0.0 1.7e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Ank_2 PF12796.7 GAX16760.1 - 9.8e-17 61.3 0.1 8.9e-06 26.2 0.0 4.9 4 2 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX16760.1 - 5e-12 45.8 5.5 0.0029 17.9 0.0 6.1 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX16760.1 - 3.2e-10 40.0 14.0 0.12 12.9 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 GAX16760.1 - 3.9e-06 26.8 11.5 0.17 12.5 0.0 7.4 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 GAX16760.1 - 1.9e-05 25.1 5.9 0.2 12.3 0.0 5.7 4 2 3 7 7 7 3 Ankyrin repeats (many copies) PI3_PI4_kinase PF00454.27 GAX16761.1 - 5.1e-46 157.5 0.0 1.5e-45 156.0 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GAX16761.1 - 3.1e-11 42.9 0.5 1.3e-10 40.9 0.2 2.3 2 0 0 2 2 2 1 FATC domain Ubie_methyltran PF01209.18 GAX16763.1 - 5.5e-79 264.8 0.0 8.8e-79 264.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GAX16763.1 - 2.1e-15 57.1 0.1 6e-15 55.7 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX16763.1 - 2.2e-15 57.1 0.1 5.6e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX16763.1 - 1.3e-12 47.7 0.0 2.6e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX16763.1 - 3.5e-11 43.7 0.2 8.4e-11 42.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX16763.1 - 4.3e-09 36.4 0.0 6.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRK PF00485.18 GAX16764.1 - 9.1e-10 38.6 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAX16764.1 - 2.2e-06 28.3 0.0 5.2e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX16764.1 - 0.00011 22.7 0.0 0.00016 22.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 GAX16764.1 - 0.00024 21.3 0.0 0.0016 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX16764.1 - 0.00038 19.8 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 GAX16764.1 - 0.00075 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 GAX16764.1 - 0.0061 16.5 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase KTI12 PF08433.10 GAX16764.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 dNK PF01712.19 GAX16764.1 - 0.024 14.5 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 GAX16764.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAX16764.1 - 0.034 14.6 0.2 0.84 10.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain 6PF2K PF01591.18 GAX16764.1 - 0.034 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 GAX16764.1 - 0.04 14.0 0.0 0.092 12.8 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 GAX16764.1 - 0.043 13.5 0.0 6.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase T2SSE PF00437.20 GAX16764.1 - 0.046 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 GAX16764.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX16764.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 GAX16764.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 GAX16764.1 - 0.16 12.5 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter SMC_N PF02463.19 GAX16764.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 GAX16764.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 GAX16764.1 - 0.21 11.3 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 GAX16765.1 - 6e-08 33.2 12.2 1.2e-07 32.3 0.2 4.5 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX16765.1 - 5.6e-05 23.4 0.3 0.014 15.7 0.1 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX16765.1 - 0.0064 15.9 0.1 0.87 8.9 0.0 2.4 1 1 0 2 2 2 2 WD40-like domain Cyanate_lyase PF02560.14 GAX16766.1 - 2.2e-28 97.9 0.2 3.1e-28 97.4 0.2 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 GAX16766.1 - 2.6e-06 27.4 0.1 3.9e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 GAX16766.1 - 0.0075 16.6 0.2 0.015 15.6 0.2 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 GAX16766.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 ERCC4 PF02732.15 GAX16767.1 - 8.8e-17 61.7 0.2 1.4e-15 57.8 0.0 3.0 3 1 1 4 4 4 1 ERCC4 domain HHH_5 PF14520.6 GAX16767.1 - 0.026 15.1 0.0 0.073 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain PH PF00169.29 GAX16768.1 - 5.7e-19 68.6 0.2 6.6e-10 39.4 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 GAX16768.1 - 1.4e-07 31.8 3.5 0.0039 17.6 0.5 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 GAX16768.1 - 0.00037 20.7 0.2 0.0097 16.2 0.0 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain PH_4 PF15404.6 GAX16768.1 - 0.085 12.6 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain CinA_KH PF18146.1 GAX16768.1 - 0.14 12.3 0.0 6.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain MFS_1 PF07690.16 GAX16769.1 - 3.6e-43 147.8 36.4 2.2e-42 145.3 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAX16769.1 - 0.4 8.9 14.5 0.27 9.4 0.1 4.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family UQ_con PF00179.26 GAX16771.1 - 5.7e-19 68.2 0.0 2e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme AIG1 PF04548.16 GAX16771.1 - 0.0082 15.5 0.1 0.017 14.4 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Pribosyltran PF00156.27 GAX16772.1 - 1.6e-09 37.5 0.3 3e-09 36.6 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RSS_P20 PF11757.8 GAX16773.1 - 0.087 13.3 0.6 1.2 9.6 0.1 2.6 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain VASP_tetra PF08776.11 GAX16773.1 - 0.43 10.2 11.6 2.6 7.7 0.2 5.2 6 0 0 6 6 6 0 VASP tetramerisation domain Pkinase PF00069.25 GAX16775.1 - 1.8e-15 57.1 0.0 3.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16775.1 - 6.5e-12 45.3 0.0 2.4e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase EPL1 PF10513.9 GAX16775.1 - 0.0086 16.5 0.2 0.018 15.5 0.2 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like Cupin_7 PF12973.7 GAX16776.1 - 1e-38 131.1 0.2 5.2e-34 116.0 0.0 2.6 2 1 0 2 2 2 2 ChrR Cupin-like domain Cupin_2 PF07883.11 GAX16776.1 - 0.0031 17.2 0.5 0.0089 15.7 0.1 2.0 2 0 0 2 2 2 1 Cupin domain DMSP_lyase PF16867.5 GAX16776.1 - 0.03 14.0 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase LRR_8 PF13855.6 GAX16777.1 - 1.8e-25 88.4 36.6 1.8e-06 27.6 1.9 7.3 2 1 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 GAX16777.1 - 8.2e-25 86.5 20.9 0.001 19.4 0.4 8.2 6 1 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX16777.1 - 1.5e-08 34.0 29.8 0.69 10.7 0.5 11.2 11 2 1 12 12 12 3 Leucine Rich Repeat LRR_2 PF07723.13 GAX16777.1 - 1.6e-07 31.7 1.0 0.36 11.6 0.2 6.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 GAX16777.1 - 0.0057 16.2 5.9 1.9 8.0 0.1 3.7 2 1 1 4 4 4 2 Leucine-rich repeat RskA PF10099.9 GAX16777.1 - 0.046 14.0 2.9 0.09 13.1 2.9 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF411 PF04214.13 GAX16777.1 - 0.11 12.5 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF Coa1 PF08695.10 GAX16779.1 - 0.00025 20.8 0.1 0.00046 19.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Serinc PF03348.15 GAX16780.1 - 5.4e-76 256.2 5.8 6.3e-76 256.0 5.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) BID PF06393.11 GAX16782.1 - 0.94 9.0 7.8 13 5.3 0.0 2.2 2 0 0 2 2 2 0 BH3 interacting domain (BID) IFRD PF05004.13 GAX16783.1 - 5.3e-31 107.9 0.9 5.3e-31 107.9 0.9 1.4 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) DUF2974 PF11187.8 GAX16783.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Transposase_24 PF03004.14 GAX16783.1 - 0.76 9.9 4.7 6.5 6.9 1.4 2.6 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Peptidase_M16 PF00675.20 GAX16784.1 - 1.7e-53 180.6 0.2 2.7e-53 180.0 0.2 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX16784.1 - 8.6e-35 120.4 0.0 4.5e-34 118.0 0.0 2.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain MtrB PF05440.12 GAX16784.1 - 0.094 13.1 0.2 9.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B M16C_assoc PF08367.11 GAX16784.1 - 0.13 11.3 0.6 0.5 9.5 0.6 1.9 2 1 0 2 2 2 0 Peptidase M16C associated FKBP_C PF00254.28 GAX16785.1 - 1.9e-13 50.5 0.0 3.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_10 PF13374.6 GAX16787.1 - 1.9e-06 27.5 2.7 7.7e-06 25.6 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX16787.1 - 6.1e-06 25.9 1.3 0.00048 20.0 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX16787.1 - 3.1e-05 23.8 1.0 4.2e-05 23.4 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.6 GAX16787.1 - 0.00011 22.2 2.6 0.011 15.9 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX16787.1 - 0.00018 21.7 1.1 0.00018 21.7 1.1 2.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX16787.1 - 0.0017 18.1 1.1 0.028 14.3 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX16787.1 - 0.0074 16.2 0.2 0.0074 16.2 0.2 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX16787.1 - 0.035 14.6 0.3 0.14 12.6 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX16787.1 - 0.079 13.8 3.2 0.8 10.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX16787.1 - 0.083 13.6 5.3 1.5 9.6 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2722 PF10846.8 GAX16788.1 - 1.8 7.4 6.4 2 7.3 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DDE_Tnp_1_7 PF13843.6 GAX16789.1 - 4.2e-13 49.3 0.1 2.7e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 Transposase IS4 ubiquitin PF00240.23 GAX16790.1 - 1e-09 38.0 0.1 2.9e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family Tudor-knot PF11717.8 GAX16790.1 - 0.0019 18.0 0.5 0.0045 16.9 0.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Ubiquitin_2 PF14560.6 GAX16790.1 - 0.035 14.5 0.0 0.085 13.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain MBT PF02820.18 GAX16790.1 - 0.12 12.8 0.2 0.26 11.7 0.2 1.5 1 0 0 1 1 1 0 mbt repeat DWNN PF08783.11 GAX16791.1 - 1.5e-17 63.6 0.0 3e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 DWNN domain U-box PF04564.15 GAX16791.1 - 0.00018 21.6 0.0 0.00048 20.2 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 GAX16791.1 - 0.00023 20.9 0.5 0.00037 20.3 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CBF PF03914.17 GAX16792.1 - 7.6e-34 117.2 1.5 1.1e-33 116.7 0.2 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Treacle PF03546.14 GAX16792.1 - 0.098 11.5 0.8 0.14 11.0 0.8 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle ANAPC4_WD40 PF12894.7 GAX16793.1 - 0.032 14.5 0.9 1.1 9.6 0.1 3.6 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX16793.1 - 0.058 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 GAX16793.1 - 0.081 13.8 0.7 54 4.9 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat CDC45 PF02724.14 GAX16793.1 - 0.79 7.9 11.6 0.99 7.6 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GAX16793.1 - 4.9 6.5 18.3 7.5 5.9 18.3 1.3 1 0 0 1 1 1 0 SDA1 DUF1373 PF07117.11 GAX16793.1 - 8.3 6.4 8.2 16 5.4 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) UbiA PF01040.18 GAX16794.1 - 3.9e-33 114.8 7.6 1e-32 113.5 7.5 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family NOP5NT PF08156.13 GAX16794.1 - 0.18 12.2 0.1 0.36 11.2 0.1 1.6 1 1 0 1 1 1 0 NOP5NT (NUC127) domain ABC_tran PF00005.27 GAX16795.1 - 1.2e-38 132.7 0.3 2.5e-21 76.6 0.0 3.4 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAX16795.1 - 3.9e-13 49.9 8.7 0.0014 18.5 0.2 4.4 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX16795.1 - 3.9e-08 32.9 0.0 0.01 15.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 GAX16795.1 - 2.4e-07 30.4 0.6 0.0039 16.7 0.1 3.7 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX16795.1 - 1.5e-06 28.2 6.3 0.0032 17.3 0.7 3.5 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAX16795.1 - 1.6e-06 28.1 1.0 0.022 14.7 0.0 3.2 2 1 1 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 GAX16795.1 - 3.6e-06 27.6 7.3 0.26 11.8 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAX16795.1 - 4.5e-06 27.2 0.0 0.0049 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX16795.1 - 5.1e-06 26.8 0.0 0.039 14.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 GAX16795.1 - 5.3e-05 22.5 2.1 0.25 10.5 0.0 2.6 2 1 0 2 2 2 2 G-protein alpha subunit NACHT PF05729.12 GAX16795.1 - 0.0001 22.2 0.0 0.079 12.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain ABC_tran_Xtn PF12848.7 GAX16795.1 - 0.00016 21.7 2.1 0.00016 21.7 2.1 2.5 2 0 0 2 2 1 1 ABC transporter AAA_24 PF13479.6 GAX16795.1 - 0.0006 19.6 0.0 0.17 11.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAX16795.1 - 0.00072 19.6 0.1 0.76 9.9 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 GAX16795.1 - 0.00077 20.0 0.0 0.14 12.7 0.0 3.1 3 1 0 3 3 2 1 AAA domain Roc PF08477.13 GAX16795.1 - 0.00094 19.4 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 GAX16795.1 - 0.0014 18.8 0.0 2 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 GAX16795.1 - 0.0036 17.6 0.0 0.93 9.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.6 GAX16795.1 - 0.0044 15.8 7.0 1.4 7.5 2.5 3.4 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 GAX16795.1 - 0.0083 15.9 0.0 1 9.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAX16795.1 - 0.009 16.0 3.5 3.6 7.4 0.2 3.4 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAX16795.1 - 0.014 15.4 0.0 5.2 7.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GAX16795.1 - 0.054 13.2 0.0 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DLIC PF05783.11 GAX16795.1 - 0.058 12.2 0.1 4.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 GAX16795.1 - 0.059 13.4 0.1 0.63 10.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 GAX16795.1 - 0.08 12.3 0.3 4.6 6.5 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAX16795.1 - 0.084 13.3 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 GAX16795.1 - 0.09 12.2 0.4 13 5.1 0.0 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein DAP3 PF10236.9 GAX16795.1 - 0.091 11.9 2.2 3.8 6.6 0.0 2.6 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_27 PF13514.6 GAX16795.1 - 0.15 11.7 3.4 1.1 8.8 0.0 3.2 3 1 1 4 4 3 0 AAA domain DUF87 PF01935.17 GAX16795.1 - 0.16 12.1 5.6 0.21 11.6 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain MutS_V PF00488.21 GAX16795.1 - 0.17 11.9 1.0 45 4.0 0.0 3.9 5 0 0 5 5 5 0 MutS domain V CENP-Q PF13094.6 GAX16795.1 - 0.22 11.7 9.9 0.24 11.6 3.6 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ATP_bind_1 PF03029.17 GAX16795.1 - 0.23 11.2 1.9 2.4 7.9 0.0 3.1 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein DUF3987 PF13148.6 GAX16795.1 - 0.47 9.4 3.3 3.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) APG6_N PF17675.1 GAX16795.1 - 0.61 10.6 12.4 4.4 7.8 7.5 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 GAX16795.1 - 1.5 9.3 6.3 1.1 9.7 2.9 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) S1 PF00575.23 GAX16796.1 - 9.5e-26 90.0 0.0 4.3e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.6 GAX16796.1 - 0.0012 18.8 0.0 3.6 7.7 0.0 3.3 3 1 0 3 3 3 2 S1 domain RsgI_N PF12791.7 GAX16796.1 - 0.043 13.7 0.8 20 5.2 0.0 3.5 4 0 0 4 4 4 0 Anti-sigma factor N-terminus RNase_II_C_S1 PF18614.1 GAX16796.1 - 0.046 13.7 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain 2OG-FeII_Oxy_2 PF13532.6 GAX16797.1 - 2.7e-14 53.8 0.0 4.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M7 PF02031.16 GAX16797.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family ABC_membrane PF00664.23 GAX16798.1 - 1.2e-52 179.3 7.8 1.3e-45 156.2 0.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX16798.1 - 1.4e-34 119.5 0.0 2.4e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAX16798.1 - 9.8e-06 25.2 0.8 0.00039 19.9 0.1 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 GAX16798.1 - 0.0042 16.4 0.2 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 GAX16798.1 - 0.01 16.2 0.3 0.029 14.7 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GAX16798.1 - 0.017 14.7 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAX16798.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 GAX16798.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX16798.1 - 0.03 14.6 0.1 0.14 12.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX16798.1 - 0.035 13.8 4.0 0.98 9.1 0.0 3.4 3 1 1 4 4 4 0 AAA domain SbcCD_C PF13558.6 GAX16798.1 - 0.077 13.2 0.3 0.84 9.9 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 GAX16798.1 - 0.14 12.0 0.0 0.96 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2614 PF11023.8 GAX16798.1 - 0.5 10.5 3.9 3.8 7.6 2.9 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF2207 PF09972.9 GAX16798.1 - 1.4 7.6 2.8 1.2 7.9 0.6 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Fascin PF06268.13 GAX16799.1 - 8.2e-08 32.4 0.3 1e-05 25.7 0.1 3.2 2 1 1 3 3 3 1 Fascin domain RicinB_lectin_2 PF14200.6 GAX16799.1 - 2.6e-06 28.0 3.9 0.22 12.3 0.3 4.7 4 1 1 5 5 5 3 Ricin-type beta-trefoil lectin domain-like DER1 PF04511.15 GAX16801.1 - 3.6e-28 98.8 5.1 5.6e-28 98.2 5.1 1.3 1 0 0 1 1 1 1 Der1-like family LAB_N PF07578.11 GAX16801.1 - 0.026 14.6 1.1 0.058 13.5 1.1 1.5 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain TetR_C_20 PF17925.1 GAX16801.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF5577 PF17740.1 GAX16803.1 - 0.015 15.0 0.5 0.023 14.4 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5577) Trypsin PF00089.26 GAX16805.1 - 1.2e-34 120.1 0.0 2.3e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin zf-RING_2 PF13639.6 GAX16807.1 - 2e-11 44.0 7.9 4.1e-11 43.0 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX16807.1 - 9.2e-08 32.3 6.0 2.3e-07 31.0 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAX16807.1 - 8.8e-07 28.9 3.5 1.7e-06 28.0 3.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX16807.1 - 1.5e-06 28.1 2.6 1.5e-06 28.1 2.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX16807.1 - 1.9e-06 27.6 8.4 3.5e-06 26.8 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX16807.1 - 3.7e-06 26.7 9.2 6.6e-06 25.9 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX16807.1 - 7e-06 25.7 5.3 7e-06 25.7 5.3 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 GAX16807.1 - 3.9e-05 23.5 7.3 6.9e-05 22.7 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 GAX16807.1 - 0.00011 22.0 4.0 0.00024 20.8 4.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 GAX16807.1 - 0.011 15.4 6.2 0.024 14.3 6.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAX16807.1 - 0.015 15.4 10.9 0.025 14.7 10.9 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 GAX16807.1 - 0.034 14.3 8.0 0.095 12.9 8.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Tmpp129 PF10272.9 GAX16807.1 - 0.038 13.3 3.1 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-RING-like PF08746.11 GAX16807.1 - 0.26 11.6 7.6 0.51 10.7 7.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 GAX16807.1 - 0.86 9.5 9.6 2.1 8.2 9.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PPR_2 PF13041.6 GAX16808.1 - 1.9e-16 60.0 0.7 1.6e-05 25.0 0.1 6.7 7 1 1 8 8 8 4 PPR repeat family PPR_3 PF13812.6 GAX16808.1 - 1.5e-08 34.6 0.0 0.0026 17.8 0.0 3.2 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 GAX16808.1 - 6.2e-06 26.1 2.1 0.27 11.6 0.0 6.4 7 0 0 7 7 7 1 PPR repeat PPR_1 PF12854.7 GAX16808.1 - 0.032 13.9 2.6 20 5.0 0.0 5.2 6 0 0 6 6 6 0 PPR repeat GPHR_N PF12537.8 GAX16808.1 - 0.071 13.2 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal PAS_9 PF13426.7 GAX16809.1 - 8.6e-16 58.1 0.0 2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 GAX16809.1 - 7.1e-07 29.2 7.2 1.6e-06 28.1 7.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX16809.1 - 2.4e-06 27.6 7.9 4.8e-06 26.6 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 GAX16809.1 - 0.0017 18.6 0.0 0.004 17.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 GAX16809.1 - 0.0053 16.7 0.3 0.024 14.6 0.0 2.1 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.10 GAX16809.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 PAS fold Peptidase_S64 PF08192.11 GAX16809.1 - 0.12 10.9 1.2 0.16 10.4 1.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAS_8 PF13188.7 GAX16809.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain PBP1_TM PF14812.6 GAX16809.1 - 0.17 12.3 4.9 0.35 11.3 4.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LrgB PF04172.16 GAX16810.1 - 1.2e-33 116.5 18.2 1.2e-33 116.5 18.2 2.2 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 GAX16810.1 - 0.00086 19.2 5.0 0.00086 19.2 5.0 3.4 4 0 0 4 4 4 1 LrgA family CD52 PF15116.6 GAX16810.1 - 2.5 8.2 8.3 0.91 9.6 0.5 3.7 3 0 0 3 3 3 0 CAMPATH-1 antigen Syntaxin PF00804.25 GAX16811.1 - 0.013 15.2 1.3 0.013 15.2 1.3 2.8 2 1 1 3 3 3 0 Syntaxin MCPsignal PF00015.21 GAX16811.1 - 0.03 14.1 0.2 0.066 13.0 0.2 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CDC37_N PF03234.14 GAX16811.1 - 0.034 15.1 1.9 0.034 15.1 1.9 2.4 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Prominin PF05478.11 GAX16811.1 - 0.075 11.0 2.5 0.039 11.9 0.2 1.6 1 1 0 2 2 2 0 Prominin SHE3 PF17078.5 GAX16811.1 - 0.079 12.7 12.8 0.073 12.8 7.0 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DNA_photolyase PF00875.18 GAX16812.1 - 1.9e-20 73.5 0.0 3.1e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase CBM_6 PF03422.15 GAX16813.1 - 2.1e-78 260.7 4.1 6.6e-18 65.2 0.1 5.1 5 0 0 5 5 5 5 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX16813.1 - 1.2e-26 93.0 1.4 3.6e-06 27.1 0.0 5.4 5 0 0 5 5 5 4 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX16813.1 - 6.9e-16 58.6 4.8 0.0012 19.0 0.0 5.6 5 1 0 5 5 5 4 Carbohydrate binding module (family 35) Iron_transport PF10634.9 GAX16813.1 - 7.5e-07 29.4 0.0 0.88 9.7 0.0 4.3 4 0 0 4 4 4 2 Fe2+ transport protein CBM_4_9 PF02018.17 GAX16813.1 - 0.00061 20.1 2.4 0.51 10.6 0.0 4.7 4 1 0 4 4 4 1 Carbohydrate binding domain adh_short PF00106.25 GAX16814.1 - 3.3e-20 72.4 0.0 7.6e-12 45.1 0.0 2.3 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX16814.1 - 1.8e-18 66.9 0.0 1.6e-13 50.7 0.0 2.2 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 2OG-FeII_Oxy_3 PF13640.6 GAX16815.1 - 2.7e-16 60.2 0.0 5.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 GAX16815.1 - 3e-07 30.9 6.9 6.3e-07 29.8 6.9 1.6 1 0 0 1 1 1 1 ShK domain-like zf-CCCH_7 PF18586.1 GAX16815.1 - 0.33 11.3 1.4 0.85 10.0 1.4 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Thyroglobulin_1 PF00086.18 GAX16815.1 - 3.3 7.4 6.5 21 4.9 3.0 2.4 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat zf-C3HC4_2 PF13923.6 GAX16816.1 - 3.8e-10 39.4 7.2 7.8e-10 38.4 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX16816.1 - 7e-08 32.2 8.3 1.7e-07 31.0 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX16816.1 - 2.5e-07 30.5 5.6 4.6e-07 29.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 GAX16816.1 - 1.7e-06 27.8 1.5 1.7e-06 27.8 1.5 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 GAX16816.1 - 1.7e-06 27.9 9.4 3.3e-06 26.9 9.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAX16816.1 - 2.5e-06 27.7 8.1 2.5e-06 27.7 8.1 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAX16816.1 - 2.7e-06 27.4 10.3 2.7e-06 27.4 10.3 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAX16816.1 - 2.9e-06 27.2 3.0 2.9e-06 27.2 3.0 2.8 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX16816.1 - 2.5e-05 24.0 7.0 4.6e-05 23.2 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf_CCCH_4 PF18345.1 GAX16816.1 - 8.1e-05 22.5 2.5 0.00019 21.4 2.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-Nse PF11789.8 GAX16816.1 - 0.00012 21.8 3.3 0.0002 21.1 3.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 GAX16816.1 - 0.00037 20.7 3.1 0.0013 19.0 3.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 GAX16816.1 - 0.0023 17.5 4.6 0.0042 16.7 4.6 1.4 1 0 0 1 1 1 1 P-11 zinc finger Siva PF05458.12 GAX16816.1 - 0.02 14.6 1.7 0.021 14.5 0.3 1.7 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-RING_10 PF16685.5 GAX16816.1 - 0.064 13.4 5.0 0.059 13.5 3.3 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 GAX16816.1 - 0.073 12.9 5.9 0.15 12.0 5.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Sporozoite_P67 PF05642.11 GAX16816.1 - 0.11 10.6 5.2 0.12 10.4 5.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-CCCH_4 PF18044.1 GAX16816.1 - 0.93 9.4 11.6 0.067 13.0 1.4 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger TERB2 PF15101.6 GAX16816.1 - 2.8 7.9 9.4 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 PPR_2 PF13041.6 GAX16817.1 - 2.6e-13 49.9 3.4 0.00076 19.6 0.1 8.0 9 0 0 9 9 9 3 PPR repeat family PPR_long PF17177.4 GAX16817.1 - 9.9e-11 41.4 2.8 2.5e-06 27.0 0.1 3.9 2 1 3 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GAX16817.1 - 2.4e-10 40.3 0.0 0.00021 21.3 0.0 6.0 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 GAX16817.1 - 9.8e-09 34.9 10.8 0.00015 21.7 0.0 8.2 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 GAX16817.1 - 0.01 15.5 6.3 3.1 7.6 0.1 5.3 7 0 0 7 7 7 0 PPR repeat CDT1_C PF16679.5 GAX16817.1 - 0.052 14.0 1.0 5.7 7.4 0.0 4.1 5 0 0 5 5 5 0 DNA replication factor Cdt1 C-terminal domain Aminotran_1_2 PF00155.21 GAX16818.1 - 8.4e-45 153.5 0.0 1e-44 153.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX16818.1 - 0.00013 20.7 0.0 0.0002 20.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 GAX16819.1 - 6e-27 94.7 0.0 8.2e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16819.1 - 3e-24 85.7 0.0 3.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX16819.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DHHA2 PF02833.14 GAX16820.1 - 7.2e-21 74.9 0.0 1.4e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 GAX16820.1 - 7.2e-09 35.8 0.1 1.4e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 DHH family YceD PF02620.17 GAX16822.1 - 0.00062 19.9 0.8 0.016 15.3 0.8 2.6 1 1 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Trypsin PF00089.26 GAX16824.1 - 2.5e-49 168.1 0.0 3.7e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX16824.1 - 0.036 15.0 0.0 0.087 13.7 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain AAA_12 PF13087.6 GAX16825.1 - 8.5e-51 172.4 0.1 1.7e-50 171.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX16825.1 - 2.2e-43 148.9 0.0 5.3e-43 147.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX16825.1 - 7e-11 42.2 0.1 2e-07 30.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 GAX16825.1 - 7.2e-11 42.6 0.0 6.3e-10 39.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAX16825.1 - 6.8e-07 29.3 0.3 0.15 11.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 GAX16825.1 - 8.6e-05 22.2 0.0 0.00031 20.4 0.0 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 GAX16825.1 - 0.00028 20.7 0.0 0.012 15.4 0.0 2.6 3 0 0 3 3 2 1 DEAD/DEAH box helicase ResIII PF04851.15 GAX16825.1 - 0.00033 20.7 0.0 0.00092 19.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 GAX16825.1 - 0.0034 17.2 0.0 0.092 12.6 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA PF00004.29 GAX16825.1 - 0.0041 17.5 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX16825.1 - 0.0045 17.3 0.1 0.49 10.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 GAX16825.1 - 0.0092 15.6 0.0 0.033 13.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 GAX16825.1 - 0.013 15.0 0.0 0.54 9.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein UvrD_C PF13361.6 GAX16825.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 GAX16825.1 - 0.055 12.7 0.1 0.21 10.8 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 GAX16825.1 - 0.059 13.2 0.3 0.25 11.2 0.3 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.12 GAX16825.1 - 0.074 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 GAX16825.1 - 0.1 12.5 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 GAX16825.1 - 0.18 11.4 0.1 0.38 10.3 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CENP-S PF15630.6 GAX16826.1 - 5.7e-21 74.7 0.2 8.8e-21 74.1 0.2 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAX16826.1 - 9.5e-10 38.6 0.1 1.6e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF4332 PF14229.6 GAX16826.1 - 0.00022 21.4 0.2 0.00036 20.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) TFIID-31kDa PF02291.15 GAX16826.1 - 0.0062 16.6 0.7 0.023 14.7 0.4 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 GAX16826.1 - 0.038 14.4 0.5 0.038 14.4 0.5 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Mpv17_PMP22 PF04117.12 GAX16827.1 - 3.9e-18 65.4 0.5 9.2e-18 64.2 0.5 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-RING_2 PF13639.6 GAX16828.1 - 9e-11 41.9 9.6 2.4e-10 40.6 9.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX16828.1 - 1.6e-06 27.7 6.4 9.8e-06 25.2 5.3 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GAX16828.1 - 3.8e-06 26.9 5.2 9e-06 25.7 5.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAX16828.1 - 7.6e-06 26.1 10.4 3.3e-05 24.1 10.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX16828.1 - 0.00025 20.8 9.1 0.00053 19.8 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX16828.1 - 0.00047 20.1 1.9 0.00047 20.1 1.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX16828.1 - 0.00055 19.8 9.1 0.0013 18.6 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX16828.1 - 0.0054 16.9 8.0 0.017 15.2 8.0 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain Nop25 PF09805.9 GAX16828.1 - 0.0061 17.0 0.6 0.0089 16.5 0.6 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) Zn_ribbon_17 PF17120.5 GAX16828.1 - 0.011 15.4 9.1 0.031 13.9 9.1 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Kinetochor_Ybp2 PF08568.10 GAX16828.1 - 0.02 13.4 0.3 0.026 13.0 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin zf-RING_5 PF14634.6 GAX16828.1 - 0.028 14.4 7.6 0.074 13.0 7.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain OATP PF03137.20 GAX16828.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Prok-RING_4 PF14447.6 GAX16828.1 - 0.51 10.2 8.1 1.4 8.8 8.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 GAX16828.1 - 0.98 9.6 11.4 2.3 8.4 11.4 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 GAX16828.1 - 2.5 8.5 8.0 4.9 7.5 8.0 1.6 1 0 0 1 1 1 0 RING-like domain WW PF00397.26 GAX16829.1 - 5.6e-08 32.7 0.4 2.5e-07 30.7 0.4 2.2 1 0 0 1 1 1 1 WW domain RE_AspBHI_N PF18062.1 GAX16829.1 - 0.0059 16.2 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Restriction endonuclease AspBHI N-terminal Ribosomal_L30_N PF08079.12 GAX16829.1 - 9.6 6.5 10.3 1.8 8.8 5.6 2.1 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain tRNA-synt_1c PF00749.21 GAX16830.1 - 1.3e-88 296.9 0.0 7.4e-88 294.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAX16830.1 - 1.1e-36 126.4 0.0 2.8e-36 125.0 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain NAD_binding_6 PF08030.12 GAX16831.1 - 3e-17 63.2 0.0 2e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAX16831.1 - 5e-15 55.7 7.6 5e-15 55.7 7.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAX16831.1 - 2.2e-08 34.2 0.0 1.1e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 GAX16831.1 - 0.0004 21.0 0.0 0.0067 17.1 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Pkinase PF00069.25 GAX16832.1 - 7.6e-75 251.7 0.0 8.7e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX16832.1 - 5.4e-32 111.1 0.0 7.6e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX16832.1 - 0.00036 19.6 0.0 0.0021 17.0 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAX16832.1 - 0.00068 19.0 0.1 0.021 14.1 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 GAX16832.1 - 0.012 15.6 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAX16832.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 GAX16832.1 - 0.23 10.8 0.3 0.49 9.7 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPM_phosphatase PF04536.14 GAX16833.1 - 3e-07 30.7 0.0 6.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 TPM domain Prok-RING_4 PF14447.6 GAX16833.1 - 5.4e-07 29.4 5.0 5.4e-07 29.4 5.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAX16833.1 - 1.9e-06 27.6 10.6 5.4e-06 26.2 6.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX16833.1 - 5.5e-05 23.4 11.2 0.0004 20.6 8.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAX16833.1 - 6e-05 22.9 9.3 0.00012 22.0 5.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain MOLO1 PF17175.4 GAX16833.1 - 0.0001 22.4 0.0 0.0015 18.7 0.0 2.6 2 1 0 2 2 2 1 Modulator of levamisole receptor-1 zf-C3HC4 PF00097.25 GAX16833.1 - 0.00014 21.7 12.3 0.0014 18.4 12.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX16833.1 - 0.0055 16.7 2.6 0.0055 16.7 2.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX16833.1 - 0.067 13.2 14.9 2.3 8.3 0.2 3.1 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX16833.1 - 0.11 12.4 14.7 0.095 12.6 9.6 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 GAX16833.1 - 0.14 12.7 4.2 0.26 11.8 0.2 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_6 PF14835.6 GAX16833.1 - 0.37 10.7 4.8 1.2 9.1 4.8 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAX16833.1 - 0.4 11.0 12.9 0.14 12.4 8.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 GAX16833.1 - 0.8 9.6 11.0 0.42 10.4 6.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Gal-3-0_sulfotr PF06990.11 GAX16834.1 - 3.6e-06 26.1 1.3 0.024 13.5 1.3 2.3 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 GAX16834.1 - 0.014 15.3 0.1 0.035 14.0 0.1 1.6 1 1 0 1 1 1 0 Sulfotransferase family GPR_Gpa2_C PF11970.8 GAX16835.1 - 0.28 11.3 2.1 0.27 11.4 0.2 2.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term RVT_2 PF07727.14 GAX16837.1 - 2.9e-29 102.4 0.1 1.8e-28 99.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX16837.1 - 9e-05 22.7 0.1 0.0002 21.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 GAX16837.1 - 9.5e-05 22.2 0.3 0.00024 20.9 0.3 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-PHD-like PF15446.6 GAX16837.1 - 0.074 12.7 2.3 0.17 11.5 2.3 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain CTNNBL PF08216.11 GAX16838.1 - 1.7e-22 79.6 0.5 4.3e-22 78.3 0.5 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear TRAM_LAG1_CLN8 PF03798.16 GAX16838.1 - 2e-12 47.2 6.2 2e-12 47.2 6.2 1.7 2 0 0 2 2 2 1 TLC domain SAPS PF04499.15 GAX16838.1 - 0.087 11.6 0.1 0.15 10.8 0.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Arm PF00514.23 GAX16838.1 - 0.37 10.9 4.4 0.56 10.3 0.3 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HMMR_C PF15908.5 GAX16839.1 - 0.0058 16.9 3.3 3.2 8.0 1.8 2.4 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor C-terminal HeH PF12949.7 GAX16839.1 - 0.056 13.2 0.0 0.29 10.9 0.0 2.2 1 0 0 1 1 1 0 HeH/LEM domain Ndr PF03096.14 GAX16839.1 - 0.14 10.8 0.4 0.25 10.0 0.4 1.3 1 0 0 1 1 1 0 Ndr family AAA_23 PF13476.6 GAX16839.1 - 0.23 11.9 5.1 0.1 13.1 2.2 1.9 2 0 0 2 2 2 0 AAA domain CorA PF01544.18 GAX16839.1 - 0.25 10.6 2.0 0.54 9.5 2.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 GAX16839.1 - 0.62 7.9 3.8 1 7.2 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 GAX16839.1 - 1.5 8.6 21.0 6.1 6.7 1.6 3.5 2 1 1 3 3 3 0 Septum formation initiator KASH_CCD PF14662.6 GAX16839.1 - 2.3 8.0 15.0 0.57 10.0 9.3 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 GAX16839.1 - 2.4 8.4 11.6 9 6.5 6.1 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TMCO5 PF14992.6 GAX16839.1 - 5 6.6 13.2 0.43 10.1 7.2 2.0 2 0 0 2 2 2 0 TMCO5 family DUF2175 PF09943.9 GAX16839.1 - 7.3 6.9 7.2 2.3 8.6 2.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) MFS_1 PF07690.16 GAX16840.1 - 1.5e-26 93.2 33.0 7.1e-18 64.7 16.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.6 GAX16840.1 - 4.4 7.5 12.5 0.43 10.7 0.1 3.5 3 0 0 3 3 3 0 YtpI-like protein Rad1 PF02144.16 GAX16841.1 - 3e-20 72.4 0.1 5.4e-20 71.6 0.1 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Spermine_synth PF01564.17 GAX16842.1 - 5.9e-14 51.9 0.1 1.1e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 GAX16842.1 - 0.0053 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Methyltransf_12 PF08242.12 GAX16842.1 - 0.038 14.7 0.0 0.8 10.5 0.0 2.7 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 GAX16843.1 - 8.7e-29 100.5 15.7 1.3e-28 100.0 15.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SPX PF03105.19 GAX16843.1 - 6.7e-14 52.6 1.1 2.4e-06 27.7 0.1 2.3 2 0 0 2 2 2 2 SPX domain MFS_2 PF13347.6 GAX16843.1 - 4.5e-05 22.2 1.9 4.5e-05 22.2 1.9 2.2 1 1 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 GAX16843.1 - 0.002 17.1 13.3 0.003 16.5 5.6 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 GAX16843.1 - 0.0099 14.2 9.4 0.028 12.7 0.3 2.6 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF4271 PF14093.6 GAX16843.1 - 0.013 15.4 5.1 0.035 14.0 2.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) CreA PF05981.12 GAX16844.1 - 4.3e-35 120.6 0.2 6e-35 120.1 0.2 1.2 1 0 0 1 1 1 1 CreA protein Spermine_synth PF01564.17 GAX16845.1 - 6.2e-33 113.8 0.0 1e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_12 PF08242.12 GAX16845.1 - 1.6e-05 25.6 0.2 0.0022 18.7 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX16845.1 - 0.0009 19.9 0.0 0.0036 18.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX16845.1 - 0.0047 16.7 0.5 0.19 11.5 0.2 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX16845.1 - 0.11 13.2 0.0 0.83 10.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 GAX16846.1 - 3.7e-125 417.7 0.0 6.4e-62 209.9 0.0 2.9 2 2 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX16846.1 - 6.8e-116 385.9 0.0 1.3e-57 195.0 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX16846.1 - 3.1e-39 134.7 0.0 9.9e-21 74.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAX16846.1 - 1.3e-32 113.1 0.0 2.5e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAX16846.1 - 4.1e-30 104.9 0.0 1.6e-15 57.1 0.0 3.4 2 2 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAX16846.1 - 3.5e-18 65.7 0.0 2.7e-08 33.3 0.0 3.1 2 2 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAX16846.1 - 3.5e-11 43.3 0.0 0.00015 21.8 0.0 3.3 2 2 0 2 2 2 2 NAD(P)H-binding KR PF08659.10 GAX16846.1 - 3.8e-10 40.0 2.5 0.00033 20.6 0.1 3.5 2 2 0 2 2 2 2 KR domain adh_short PF00106.25 GAX16846.1 - 2.8e-07 30.2 0.1 0.011 15.2 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX16846.1 - 1.4e-05 25.4 0.0 0.074 13.3 0.0 2.3 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 GAX16846.1 - 3.5e-05 23.5 0.0 0.96 9.0 0.0 4.6 3 1 0 3 3 3 1 NmrA-like family TrkA_N PF02254.18 GAX16846.1 - 6.9e-05 23.1 0.2 0.46 10.8 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Pyr_redox PF00070.27 GAX16846.1 - 9.2e-05 22.9 0.2 0.8 10.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAX16846.1 - 0.00017 21.5 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GAX16846.1 - 0.0027 17.4 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 GAX16846.1 - 0.0065 15.7 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAX16846.1 - 0.015 14.6 0.0 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ssDBP_DBD PF18361.1 GAX16846.1 - 0.022 14.9 0.2 0.79 9.8 0.0 2.6 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain adh_short_C2 PF13561.6 GAX16846.1 - 0.029 13.9 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase DAO PF01266.24 GAX16846.1 - 0.035 13.7 0.0 6.3 6.3 0.0 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 GAX16846.1 - 0.042 13.4 0.6 6 6.4 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TUDOR_5 PF18359.1 GAX16847.1 - 3.3e-06 26.7 0.4 6.1e-06 25.8 0.4 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 GAX16847.1 - 0.0042 17.5 1.7 0.016 15.7 0.2 2.8 3 0 0 3 3 3 1 Agenet domain Tudor_3 PF18115.1 GAX16847.1 - 0.005 16.6 0.2 0.012 15.5 0.2 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Imm53 PF15580.6 GAX16847.1 - 0.058 13.1 0.4 0.15 11.7 0.4 1.7 1 0 0 1 1 1 0 Immunity protein 53 DUSP PF06337.12 GAX16847.1 - 0.099 13.3 0.1 0.38 11.4 0.1 2.0 1 0 0 1 1 1 0 DUSP domain DUF1995 PF09353.10 GAX16848.1 - 8.4e-25 88.0 0.1 8.4e-25 88.0 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) Golgin_A5 PF09787.9 GAX16848.1 - 0.0027 17.2 1.5 0.0037 16.8 1.5 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF1682 PF07946.14 GAX16848.1 - 0.052 12.8 3.4 0.081 12.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3287 PF11690.8 GAX16848.1 - 0.053 13.3 0.1 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) SAP PF02037.27 GAX16849.1 - 6.6e-05 22.6 3.3 7.7e-05 22.3 0.0 2.9 4 1 0 4 4 4 1 SAP domain DUF3974 PF13120.6 GAX16849.1 - 0.077 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) GIDA PF01134.22 GAX16850.1 - 2e-134 448.6 0.0 5.9e-133 443.7 0.0 2.2 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 GAX16850.1 - 1.1e-60 205.5 0.2 1.9e-60 204.7 0.2 1.4 1 0 0 1 1 1 1 GidA associated domain FAD_binding_2 PF00890.24 GAX16850.1 - 2.3e-08 33.5 5.5 1.8e-05 24.0 2.7 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 GAX16850.1 - 9e-08 31.9 0.2 1.8e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX16850.1 - 3.4e-05 23.2 2.8 0.00013 21.3 2.8 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX16850.1 - 0.00093 18.5 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX16850.1 - 0.0037 17.8 0.3 0.0088 16.6 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX16850.1 - 0.0052 16.1 0.8 0.0052 16.1 0.8 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX16850.1 - 0.027 14.0 3.0 0.54 9.8 1.3 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAX16850.1 - 0.03 13.6 0.9 0.063 12.5 0.1 1.9 2 0 0 2 2 2 0 Thi4 family PPO1_KFDV PF12143.8 GAX16850.1 - 0.085 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) HI0933_like PF03486.14 GAX16850.1 - 0.1 11.3 6.6 0.057 12.1 0.9 3.0 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 GAX16850.1 - 0.11 11.7 0.3 0.22 10.7 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 GAX16850.1 - 0.26 11.6 1.6 0.7 10.2 1.6 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX16850.1 - 0.33 10.0 3.9 0.5 9.3 1.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Epimerase PF01370.21 GAX16852.1 - 2.5e-08 33.7 0.0 2e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX16852.1 - 1.3e-05 25.2 0.0 3.7e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAX16852.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAX16852.1 - 0.003 16.7 0.0 0.0064 15.6 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAX16852.1 - 0.0038 16.3 0.0 0.007 15.4 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GAX16852.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family LPD22 PF18834.1 GAX16852.1 - 0.12 12.6 0.0 0.83 9.9 0.0 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 NAD_binding_4 PF07993.12 GAX16852.1 - 0.13 11.4 0.0 13 4.9 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Xpo1 PF08389.12 GAX16853.1 - 1.8e-10 41.1 0.0 3.1e-09 37.0 0.0 3.2 3 1 0 3 3 3 1 Exportin 1-like protein Pribosyltran PF00156.27 GAX16854.1 - 5.6e-19 68.2 0.0 7.7e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 GAX16854.1 - 0.046 13.2 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 GAX16854.1 - 0.058 12.8 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF1824 PF08854.10 GAX16854.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) DUF4917 PF16263.5 GAX16854.1 - 0.15 11.4 0.0 4 6.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4917) Proteasome PF00227.26 GAX16855.1 - 4.3e-51 173.1 0.0 5.2e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX16855.1 - 4.3e-13 48.7 0.0 1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Kinesin PF00225.23 GAX16856.1 - 1.5e-90 303.5 0.6 1.5e-90 303.5 0.6 3.0 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX16856.1 - 2.8e-37 127.9 0.3 8.2e-36 123.2 0.0 3.4 3 1 0 3 3 3 1 Microtubule binding bZIP_1 PF00170.21 GAX16857.1 - 0.013 15.6 0.8 0.013 15.6 0.8 2.1 3 0 0 3 3 3 0 bZIP transcription factor Choline_transpo PF04515.12 GAX16858.1 - 2e-84 283.6 36.8 2e-84 283.6 36.8 2.6 3 0 0 3 3 3 1 Plasma-membrane choline transporter Dus PF01207.17 GAX16859.1 - 8.8e-45 153.1 0.0 1.4e-43 149.2 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) GGACT PF06094.12 GAX16860.1 - 0.029 15.0 0.0 0.059 14.0 0.0 1.5 1 1 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like Bestrophin PF01062.21 GAX16861.1 - 3.2e-45 154.8 0.1 4.1e-45 154.4 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SNase PF00565.17 GAX16861.1 - 0.018 15.5 0.0 0.18 12.3 0.0 2.3 2 0 0 2 2 2 0 Staphylococcal nuclease homologue SNF2_N PF00176.23 GAX16862.1 - 4.6e-16 58.5 0.1 1.8e-15 56.5 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX16862.1 - 9e-12 45.3 0.0 1.9e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX16862.1 - 0.00032 20.5 0.3 0.0052 16.6 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 GAX16862.1 - 0.0062 16.6 0.0 0.058 13.4 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAX16862.1 - 0.051 13.2 0.0 0.22 11.1 0.0 2.1 1 1 0 1 1 1 0 SWI2/SNF2 ATPase COG4 PF08318.12 GAX16863.1 - 1.6e-24 86.7 0.3 2.5e-24 86.0 0.3 1.3 1 0 0 1 1 1 1 COG4 transport protein cwf18 PF08315.12 GAX16863.1 - 0.0072 17.0 0.3 0.27 11.9 0.0 2.9 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor GAS PF13851.6 GAX16863.1 - 0.1 11.9 1.7 0.18 11.1 0.4 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Abhydrolase_1 PF00561.20 GAX16864.1 - 1.1e-18 67.8 0.0 2e-16 60.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX16864.1 - 5e-18 65.2 0.0 6.9e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX16864.1 - 1.7e-14 54.9 0.0 2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 GAX16864.1 - 0.0003 20.8 0.0 0.00065 19.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 GAX16864.1 - 0.00035 20.8 0.0 0.00081 19.6 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 GAX16864.1 - 0.0024 17.4 0.0 0.037 13.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 GAX16864.1 - 0.0055 16.6 0.0 2.5 8.0 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_2 PF02230.16 GAX16864.1 - 0.0058 16.5 0.0 2.6 7.8 0.0 2.5 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Ndr PF03096.14 GAX16864.1 - 0.02 13.6 0.0 0.13 11.0 0.0 1.9 1 1 0 1 1 1 0 Ndr family LIDHydrolase PF10230.9 GAX16864.1 - 0.047 13.2 0.0 1.3 8.5 0.0 2.1 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Chitin_synth_2 PF03142.15 GAX16866.1 - 1.7e-168 561.5 4.2 2.5e-168 561.0 4.2 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 GAX16866.1 - 1.6e-12 47.4 0.3 4e-10 39.7 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAX16866.1 - 5.5e-12 46.0 11.1 1.3e-11 44.8 11.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX16866.1 - 6.3e-12 45.9 0.7 8.2e-08 32.4 0.2 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX16866.1 - 1.4e-06 28.2 0.0 0.0088 15.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX16866.1 - 0.0014 18.1 0.2 0.093 12.2 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 GAX16867.1 - 4.6e-161 537.0 2.0 6.8e-161 536.5 2.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 GAX16867.1 - 1.4e-12 48.0 8.0 4.4e-12 46.3 8.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX16867.1 - 1.5e-12 47.9 0.2 5.5e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 GAX16867.1 - 2.9e-11 43.4 0.1 2.2e-08 34.1 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 GAX16867.1 - 8.9e-06 25.6 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX16867.1 - 0.00013 21.5 0.4 0.096 12.2 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 21 Amino_oxidase PF01593.24 GAX16868.1 - 1.8e-68 231.9 0.0 2.2e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX16868.1 - 9.3e-18 64.2 0.0 1.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX16868.1 - 3e-09 36.9 0.4 8.1e-08 32.2 0.4 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX16868.1 - 2e-07 31.4 0.0 0.0016 18.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAX16868.1 - 3e-06 26.3 0.0 0.0018 17.1 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 GAX16868.1 - 2.2e-05 23.9 0.0 8.2e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAX16868.1 - 6.1e-05 21.6 0.1 0.00013 20.6 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like HI0933_like PF03486.14 GAX16868.1 - 0.00026 19.8 0.1 0.004 15.9 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAX16868.1 - 0.0018 17.4 0.3 0.0098 15.0 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAX16868.1 - 0.0059 16.0 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAX16868.1 - 0.0061 15.8 0.2 0.039 13.2 0.2 2.2 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 GAX16868.1 - 0.022 14.0 0.2 0.067 12.4 0.1 1.8 2 0 0 2 2 2 0 Thi4 family IlvN PF07991.12 GAX16868.1 - 0.11 12.0 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ribosomal_L12 PF00542.19 GAX16869.1 - 1.4e-25 89.4 2.5 6.9e-24 84.0 3.7 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Unstab_antitox PF09720.10 GAX16869.1 - 0.065 13.3 0.1 8.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Putative addiction module component Aldedh PF00171.22 GAX16870.1 - 4.8e-131 437.5 0.0 5.7e-131 437.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PrpR_N PF06506.11 GAX16870.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Propionate catabolism activator DUF1118 PF06549.12 GAX16870.1 - 0.17 12.2 0.8 11 6.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1118) Ribosomal_L12 PF00542.19 GAX16871.1 - 1.9e-24 85.8 6.0 1.9e-24 85.8 6.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 GAX16871.1 - 4.1e-07 29.6 0.2 2.5e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain Aa_trans PF01490.18 GAX16872.1 - 3.7e-42 144.5 11.7 4.5e-42 144.2 11.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 7tm_7 PF08395.12 GAX16872.1 - 0.57 9.3 5.7 1.6 7.9 5.6 1.8 1 1 0 1 1 1 0 7tm Chemosensory receptor DUF2627 PF11118.8 GAX16872.1 - 1 10.0 0.0 1 10.0 0.0 3.6 5 1 0 5 5 5 0 Protein of unknown function (DUF2627) SPC12 PF06645.13 GAX16872.1 - 8.5 6.6 8.0 6.6 6.9 0.0 4.0 3 1 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) AAA PF00004.29 GAX16873.1 - 3.1e-34 118.2 0.0 6.2e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX16873.1 - 3e-07 31.0 0.2 7e-06 26.5 0.2 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX16873.1 - 4.4e-06 27.0 0.2 0.00057 20.2 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAX16873.1 - 1e-05 25.5 0.0 3.6e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX16873.1 - 1.2e-05 25.5 0.0 2.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAX16873.1 - 0.00033 21.2 0.0 0.00065 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAX16873.1 - 0.0005 19.5 0.0 0.00096 18.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GAX16873.1 - 0.00068 19.3 0.6 0.065 12.8 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 GAX16873.1 - 0.00096 18.9 0.3 0.0024 17.7 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain Rad17 PF03215.15 GAX16873.1 - 0.00097 19.1 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 GAX16873.1 - 0.001 19.6 0.0 0.0026 18.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 GAX16873.1 - 0.004 16.9 0.0 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX16873.1 - 0.0071 16.5 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAX16873.1 - 0.0082 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 GAX16873.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAX16873.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 GAX16873.1 - 0.018 14.9 0.0 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 GAX16873.1 - 0.022 14.5 0.0 0.07 12.9 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GAX16873.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAX16873.1 - 0.046 12.9 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 GAX16873.1 - 0.09 12.5 0.0 0.88 9.3 0.0 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 GAX16873.1 - 0.091 12.8 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNase_PH PF01138.21 GAX16875.1 - 5.2e-31 107.9 0.0 4.8e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX16875.1 - 4.5e-17 61.8 0.2 3e-10 40.0 0.0 2.8 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 GAX16875.1 - 2.4e-07 30.5 0.1 6.8e-07 29.0 0.1 1.9 1 0 0 1 1 1 1 KH domain S1 PF00575.23 GAX16875.1 - 2.8e-06 27.6 0.3 8e-06 26.1 0.3 1.8 1 1 0 1 1 1 1 S1 RNA binding domain PNPase PF03726.14 GAX16875.1 - 9.6e-05 22.8 0.2 0.00021 21.7 0.2 1.6 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_5 PF13184.6 GAX16875.1 - 0.017 15.2 0.1 0.042 13.9 0.1 1.7 1 0 0 1 1 1 0 NusA-like KH domain CK_II_beta PF01214.18 GAX16876.1 - 1.5e-64 217.2 0.0 1.8e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF35_N PF12172.8 GAX16876.1 - 0.046 13.6 0.5 0.1 12.5 0.5 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1077 PF06417.12 GAX16877.1 - 2e-29 102.0 6.6 2.8e-29 101.5 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Polysacc_synt_3 PF13440.6 GAX16877.1 - 0.0035 16.6 2.0 0.0042 16.3 2.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein peroxidase PF00141.23 GAX16878.1 - 2.4e-44 151.7 0.0 3.1e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Glyco_transf_20 PF00982.21 GAX16880.1 - 3e-116 388.9 0.0 1.3e-103 347.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAX16880.1 - 1.5e-41 142.1 0.0 3.4e-41 140.9 0.0 1.5 2 0 0 2 2 2 1 Trehalose-phosphatase PALP PF00291.25 GAX16881.1 - 9.9e-67 225.4 0.2 1.1e-66 225.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UPF1_Zn_bind PF09416.10 GAX16882.1 - 1.2e-61 207.2 5.4 2e-61 206.4 4.3 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 GAX16882.1 - 2e-56 190.8 0.0 3.2e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX16882.1 - 1.5e-45 156.1 10.9 1.4e-28 100.4 0.1 2.7 2 1 1 3 3 3 2 AAA domain DUF5599 PF18141.1 GAX16882.1 - 2.8e-18 65.9 0.0 5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GAX16882.1 - 4.8e-16 59.0 1.3 2.1e-15 56.9 1.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX16882.1 - 1.7e-11 44.7 0.2 8.1e-11 42.5 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX16882.1 - 2.7e-05 24.4 0.1 8.6e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 GAX16882.1 - 3.8e-05 23.6 0.4 0.00011 22.1 0.4 1.8 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 GAX16882.1 - 6.1e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAX16882.1 - 0.00013 21.6 0.4 0.0026 17.3 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 GAX16882.1 - 0.00014 21.2 2.1 0.00082 18.7 0.2 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 GAX16882.1 - 0.0015 18.4 0.2 0.0032 17.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.14 GAX16882.1 - 0.0017 17.6 0.1 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase PhoH PF02562.16 GAX16882.1 - 0.0044 16.5 0.1 0.0098 15.4 0.0 1.6 2 0 0 2 2 1 1 PhoH-like protein Viral_helicase1 PF01443.18 GAX16882.1 - 0.0048 16.7 0.3 3.2 7.4 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 GAX16882.1 - 0.012 16.0 0.5 0.028 14.8 0.1 1.9 2 0 0 2 2 1 0 AAA ATPase domain SRP54 PF00448.22 GAX16882.1 - 0.015 15.0 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 GAX16882.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.14 GAX16882.1 - 0.043 13.8 0.2 0.081 12.9 0.2 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_10 PF12846.7 GAX16882.1 - 0.054 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ROQ_II PF18386.1 GAX16882.1 - 0.11 12.3 1.0 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 Roquin II domain Ribosomal_S13_N PF08069.12 GAX16882.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_5 PF07728.14 GAX16882.1 - 0.13 12.2 0.0 0.55 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAX16882.1 - 0.15 11.5 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Radial_spoke PF04712.12 GAX16882.1 - 0.28 10.1 1.8 0.51 9.2 1.8 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein FH2 PF02181.23 GAX16884.1 - 6.6e-50 170.3 13.3 3.7e-48 164.5 13.3 2.3 1 1 0 1 1 1 1 Formin Homology 2 Domain Chlamy_scaf PF09675.10 GAX16884.1 - 0.0033 17.8 0.1 0.079 13.3 0.0 3.1 3 0 0 3 3 3 1 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Candida_ALS PF05792.13 GAX16884.1 - 0.07 13.7 0.5 0.16 12.6 0.5 1.5 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) DUF573 PF04504.14 GAX16884.1 - 0.45 11.2 3.7 19 6.0 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function, DUF573 FAD_binding_3 PF01494.19 GAX16886.1 - 4.2e-19 69.0 0.4 4.5e-09 36.0 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAX16886.1 - 0.00043 20.5 0.2 0.00096 19.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 GAX16886.1 - 0.034 13.2 0.0 2.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DnaJ_CXXCXGXG PF00684.19 GAX16886.1 - 0.042 14.2 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 DnaJ central domain Pyr_redox_3 PF13738.6 GAX16886.1 - 0.056 12.7 0.1 0.085 12.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX16886.1 - 0.06 12.2 1.2 0.11 11.3 0.6 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 GAX16886.1 - 0.061 12.5 0.1 0.17 11.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX16886.1 - 0.071 13.7 0.0 0.56 10.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAX16886.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RHD3 PF05879.12 GAX16888.1 - 0.00067 18.0 0.3 0.0014 16.9 0.1 1.5 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) Methyltr_RsmF_N PF17125.5 GAX16888.1 - 0.17 12.4 0.5 1e+02 3.5 0.0 3.5 4 0 0 4 4 4 0 N-terminal domain of 16S rRNA methyltransferase RsmF HSA PF07529.13 GAX16889.1 - 1.7e-10 41.1 0.3 5.3e-10 39.5 0.3 1.8 1 0 0 1 1 1 1 HSA Myb_DNA-binding PF00249.31 GAX16889.1 - 0.0028 17.8 0.5 0.012 15.8 0.5 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX16889.1 - 0.043 14.1 0.3 0.14 12.5 0.3 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain ALS2CR11 PF15729.5 GAX16889.1 - 4.2 6.4 5.9 14 4.6 0.2 2.3 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 candidate 11 Asp PF00026.23 GAX16891.1 - 8e-26 91.2 0.5 1.2e-25 90.6 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX16891.1 - 3e-05 23.8 0.0 5.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TMEM70 PF06979.12 GAX16892.1 - 5.2e-09 36.6 0.9 0.00017 22.0 0.0 2.1 1 1 0 2 2 2 2 Assembly, mitochondrial proton-transport ATP synth complex PP2C PF00481.21 GAX16893.1 - 1.2e-53 182.5 0.0 1.7e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX16893.1 - 5.5e-06 26.2 0.0 2e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SGT1 PF07093.11 GAX16894.1 - 5.5e-20 71.3 4.4 9.2e-15 54.1 0.3 2.3 2 1 0 2 2 2 2 SGT1 protein Lyase_1 PF00206.20 GAX16895.1 - 1e-101 340.4 0.1 1.4e-101 340.0 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GAX16895.1 - 1.9e-25 89.0 1.4 1.8e-23 82.7 0.1 3.2 3 0 0 3 3 3 1 Fumarase C C-terminus Aminotran_3 PF00202.21 GAX16896.1 - 2e-116 389.0 0.0 2.4e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAX16896.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TonB_2 PF13103.6 GAX16897.1 - 0.0078 16.4 0.1 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 TonB C terminal PhzC-PhzF PF02567.16 GAX16898.1 - 9.5e-14 51.5 0.6 2.3e-13 50.3 0.5 1.8 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein DNA_methylase PF00145.17 GAX16899.1 - 6.1e-35 121.1 0.0 7e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Phage_int_SAM_3 PF14659.6 GAX16899.1 - 0.1 12.9 0.0 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain GMP_synt_C PF00958.22 GAX16901.1 - 9.3e-42 141.0 0.1 2.8e-41 139.5 0.0 1.9 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.28 GAX16901.1 - 5.8e-38 130.6 0.0 1.5e-37 129.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAX16901.1 - 2.7e-11 43.6 0.0 5.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 GAX16901.1 - 9.3e-07 28.2 0.0 2.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 GAX16901.1 - 0.00037 20.1 0.1 0.0011 18.6 0.1 1.8 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 GAX16901.1 - 0.0049 16.4 0.0 0.046 13.2 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAX16901.1 - 0.0077 15.1 0.1 0.015 14.1 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 GAX16901.1 - 0.11 12.5 0.0 0.75 9.8 0.0 2.4 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 GAX16901.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 GAX16901.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 GAX16901.1 - 0.17 11.5 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Asparagine synthase zf-CHY PF05495.12 GAX16902.1 - 3.9e-17 62.5 15.6 3.9e-17 62.5 15.6 3.8 2 1 1 3 3 2 1 CHY zinc finger zinc_ribbon_6 PF14599.6 GAX16902.1 - 2.2e-16 59.6 1.3 2.2e-16 59.6 1.3 3.3 3 2 0 3 3 2 1 Zinc-ribbon zf-RING_2 PF13639.6 GAX16902.1 - 9.1e-09 35.5 7.9 9.1e-09 35.5 7.9 5.3 4 1 0 4 4 3 1 Ring finger domain zf-RING_5 PF14634.6 GAX16902.1 - 1.2e-05 25.1 9.0 1.2e-05 25.1 9.0 5.8 4 2 0 4 4 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX16902.1 - 0.00026 20.9 1.6 0.00026 20.9 1.6 4.6 3 2 1 4 4 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX16902.1 - 0.00066 19.5 2.0 0.00066 19.5 2.0 5.8 5 1 1 6 6 6 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAX16902.1 - 0.0048 16.7 7.8 0.0048 16.7 7.8 5.5 4 3 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX16902.1 - 0.009 15.9 8.1 0.009 15.9 8.1 6.5 3 1 2 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_6 PF13912.6 GAX16902.1 - 0.49 10.5 0.0 0.49 10.5 0.0 5.6 7 0 0 7 7 6 0 C2H2-type zinc finger zf-met PF12874.7 GAX16902.1 - 0.63 10.5 0.1 0.63 10.5 0.1 5.5 7 1 1 8 8 7 0 Zinc-finger of C2H2 type YL1 PF05764.13 GAX16902.1 - 2.1 8.4 3.8 2.7 8.0 3.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein AAA PF00004.29 GAX16903.1 - 1.1e-40 139.0 0.0 3.7e-39 134.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAX16903.1 - 1.6e-05 24.8 0.1 4.7e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 GAX16903.1 - 9.7e-05 22.8 0.1 0.0061 17.0 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 GAX16903.1 - 0.00013 22.5 0.0 0.0004 20.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAX16903.1 - 0.0012 18.6 0.0 0.0038 17.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX16903.1 - 0.0018 18.5 0.1 0.017 15.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAX16903.1 - 0.0031 16.8 0.1 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 GAX16903.1 - 0.0039 17.2 0.0 0.03 14.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX16903.1 - 0.029 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAX16903.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 GAX16903.1 - 0.056 13.9 0.0 0.44 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 GAX16903.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 GAX16903.1 - 0.081 13.3 0.0 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 GAX16903.1 - 0.088 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX16903.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAX16903.1 - 0.16 11.7 0.0 0.47 10.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 GAX16903.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Cu-oxidase_2 PF07731.14 GAX16904.1 - 2.2e-24 85.7 1.0 2.2e-24 85.7 1.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAX16904.1 - 1.9e-14 53.7 1.9 8.3e-09 35.5 0.3 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 GAX16904.1 - 4.8e-05 23.5 0.6 0.025 14.7 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase zinc_ribbon_6 PF14599.6 GAX16905.1 - 9.9e-18 63.9 1.2 9.9e-18 63.9 1.2 3.5 3 1 0 3 3 2 1 Zinc-ribbon zf-CHY PF05495.12 GAX16905.1 - 2e-16 60.2 16.6 2e-16 60.2 16.6 3.9 2 1 1 3 3 2 1 CHY zinc finger zf-RING_2 PF13639.6 GAX16905.1 - 8.8e-09 35.6 8.0 8.8e-09 35.6 8.0 5.3 4 1 1 5 5 3 1 Ring finger domain zf-RING_5 PF14634.6 GAX16905.1 - 4.9e-07 29.6 4.8 4.9e-07 29.6 4.8 6.2 3 2 1 5 5 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX16905.1 - 0.00011 22.1 1.0 0.00011 22.1 1.0 4.7 3 2 1 4 4 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX16905.1 - 0.00033 20.4 10.5 0.00065 19.5 2.0 5.9 5 2 1 6 6 5 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAX16905.1 - 0.0057 16.5 8.0 0.0057 16.5 8.0 5.6 4 3 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX16905.1 - 0.012 15.5 7.8 0.012 15.5 7.8 6.4 3 1 3 6 6 4 0 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 GAX16905.1 - 0.61 10.6 0.1 0.61 10.6 0.1 5.3 7 0 0 7 7 6 0 Zinc-finger of C2H2 type YL1 PF05764.13 GAX16905.1 - 2.5 8.2 7.1 3.1 7.8 7.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pes-10 PF07149.11 GAX16905.1 - 5.4 6.0 5.2 6.8 5.6 5.2 1.1 1 0 0 1 1 1 0 Pes-10 Clat_adaptor_s PF01217.20 GAX16906.1 - 1.5e-42 144.9 0.3 1.9e-42 144.6 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Neurochondrin PF05536.11 GAX16906.1 - 0.023 13.1 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin AMP-binding PF00501.28 GAX16907.1 - 6e-92 308.4 0.0 7.9e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAX16907.1 - 2.4e-19 70.1 2.1 1e-18 68.1 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thioredoxin PF00085.20 GAX16908.1 - 2.7e-15 56.2 0.0 4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX16908.1 - 0.00023 21.6 0.0 0.0095 16.4 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAX16908.1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 GAX16908.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 GAX16908.1 - 0.092 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin GcpE PF04551.14 GAX16908.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 GcpE protein Thioredoxin_8 PF13905.6 GAX16908.1 - 0.16 12.3 0.0 0.55 10.6 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like ADK PF00406.22 GAX16910.1 - 2.5e-52 177.0 0.0 4.5e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX16910.1 - 4.5e-22 78.9 0.0 1e-21 77.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 GAX16910.1 - 6.4e-12 45.3 0.0 1.9e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAX16910.1 - 0.0017 18.9 0.0 0.0055 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 GAX16910.1 - 0.011 16.1 2.4 0.026 14.8 0.2 2.3 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 GAX16910.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 GAX16910.1 - 0.062 13.0 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF445 PF04286.12 GAX16911.1 - 2.9e-16 60.3 4.0 4.6e-07 30.0 0.1 4.1 3 1 1 4 4 4 4 Protein of unknown function (DUF445) MatE PF01554.18 GAX16911.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 MatE La PF05383.17 GAX16912.1 - 8.8e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 La domain DUF3439 PF11921.8 GAX16912.1 - 2.2 8.3 8.5 5.7 6.9 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mut7-C PF01927.16 GAX16913.1 - 2.4e-20 73.1 0.9 5.4e-20 72.0 0.9 1.6 1 0 0 1 1 1 1 Mut7-C RNAse domain Exo_endo_phos PF03372.23 GAX16913.1 - 1.3e-13 51.1 0.2 5.2e-09 36.0 0.1 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Methyltransf_32 PF13679.6 GAX16914.1 - 1.4e-19 70.6 0.1 3.2e-19 69.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain R3H PF01424.22 GAX16914.1 - 6.3e-07 29.3 0.1 1.4e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 R3H domain TRM13 PF05206.14 GAX16914.1 - 1.4e-05 24.8 0.2 8.6e-05 22.2 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase TRM13 MTS PF05175.14 GAX16914.1 - 6.5e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAX16914.1 - 0.00017 22.2 0.0 0.00037 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX16914.1 - 0.00045 20.9 0.0 0.0012 19.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX16914.1 - 0.00099 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAX16914.1 - 0.018 14.3 0.0 0.048 12.9 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain PrmA PF06325.13 GAX16914.1 - 0.028 13.8 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 GAX16914.1 - 0.034 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 GAX16914.1 - 0.081 12.7 0.5 0.78 9.5 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase Pox_Ag35 PF03286.14 GAX16915.1 - 0.031 14.1 7.5 0.045 13.5 7.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 GAX16915.1 - 1.1 8.8 8.8 1.5 8.3 8.8 1.2 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 GAX16915.1 - 1.8 8.2 17.5 3.9 7.1 17.5 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GAX16915.1 - 2.2 6.4 11.8 2.7 6.1 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GAX16915.1 - 2.6 6.6 12.9 4.3 5.8 12.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FYDLN_acid PF09538.10 GAX16915.1 - 3 8.6 14.8 7.7 7.3 14.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Astro_capsid_p PF12226.8 GAX16915.1 - 5 6.2 12.1 7.8 5.6 12.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein UBA2_C PF16195.5 GAX16916.1 - 0.034 14.8 2.9 0.062 14.0 2.9 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus GREB1 PF15782.5 GAX16920.1 - 3.1 4.8 5.1 3.5 4.6 5.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ERCC3_RAD25_C PF16203.5 GAX16921.1 - 2e-108 361.3 0.1 2e-108 361.3 0.1 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 GAX16921.1 - 5.5e-35 120.3 0.0 1.3e-34 119.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX16921.1 - 5.6e-14 52.5 0.1 1.6e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX16921.1 - 2e-11 44.2 0.0 5.1e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 GAX16921.1 - 0.00021 20.1 0.2 0.00058 18.7 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain CSN7a_helixI PF18392.1 GAX16922.1 - 1.5 8.8 5.6 11 6.1 2.1 2.7 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain GAT PF03127.14 GAX16923.1 - 9.2e-05 22.7 0.0 0.013 15.8 0.0 2.2 2 0 0 2 2 2 2 GAT domain CarboxypepD_reg PF13620.6 GAX16924.1 - 0.2 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Adaptin_N PF01602.20 GAX16925.1 - 5.7e-78 262.8 0.6 7.7e-78 262.3 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 GAX16925.1 - 2.2e-51 173.4 0.1 4.5e-51 172.4 0.1 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 GAX16925.1 - 1.5e-32 112.2 0.3 5.6e-32 110.4 0.3 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 GAX16925.1 - 1.6e-08 34.8 2.6 9.6e-05 22.7 0.0 5.3 3 2 2 5 5 5 1 HEAT repeats Cnd1 PF12717.7 GAX16925.1 - 1.3e-06 28.6 6.3 2.7e-05 24.3 0.0 3.9 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAX16925.1 - 0.00017 21.5 1.8 1.9 8.7 0.0 5.9 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RNA_pol_Rpb1_5 PF04998.17 GAX16925.1 - 0.015 14.8 0.1 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 HEAT PF02985.22 GAX16925.1 - 0.018 15.2 13.7 0.61 10.5 0.0 6.2 8 0 0 8 8 8 0 HEAT repeat Brix PF04427.18 GAX16926.1 - 3.7e-27 95.7 0.2 5.8e-27 95.0 0.2 1.2 1 0 0 1 1 1 1 Brix domain Mem_trans PF03547.18 GAX16927.1 - 1e-31 109.8 5.9 1.7e-31 109.0 5.9 1.3 1 1 0 1 1 1 1 Membrane transport protein DUF1700 PF08006.11 GAX16927.1 - 1.6 8.2 10.9 5.4 6.5 10.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) MFS_MOT1 PF16983.5 GAX16927.1 - 3.8 8.0 10.4 6 7.3 0.6 3.1 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily Fe_hyd_lg_C PF02906.14 GAX16928.1 - 7.8e-78 261.5 0.0 1e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 GAX16928.1 - 2.1e-20 72.6 1.4 4e-20 71.6 1.4 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Methyltransf_16 PF10294.9 GAX16929.1 - 4.3e-16 59.1 0.0 6.2e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAX16929.1 - 1.4e-08 34.5 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX16929.1 - 5.5e-08 32.5 0.0 8.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX16929.1 - 5e-07 30.4 0.0 7.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX16929.1 - 3.3e-06 27.7 0.0 5.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX16929.1 - 5.2e-06 26.4 0.0 7.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX16929.1 - 3.6e-05 23.6 0.0 5.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX16929.1 - 0.00031 20.6 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TehB PF03848.14 GAX16929.1 - 0.0014 18.1 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 GAX16929.1 - 0.0043 16.1 0.1 0.0058 15.7 0.1 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_12 PF08242.12 GAX16929.1 - 0.0075 17.0 0.0 0.012 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX16929.1 - 0.0075 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 GAX16929.1 - 0.031 14.2 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAX16929.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 GAX16929.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 GAX16929.1 - 0.21 11.1 0.1 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase AMP-binding PF00501.28 GAX16930.1 - 7.5e-44 150.0 0.0 1.1e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAX16930.1 - 2.5e-06 27.3 0.1 5.5e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GAX16930.1 - 0.00059 20.8 0.9 0.0016 19.4 0.9 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 GAX16931.1 - 0.00055 20.5 0.0 0.0016 19.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAX16931.1 - 0.089 13.2 0.2 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RNA_pol_3_Rpc31 PF11705.8 GAX16932.1 - 0.011 16.0 23.2 0.39 10.9 23.2 2.7 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 OmpH PF03938.14 GAX16932.1 - 0.48 10.8 13.2 0.051 13.9 7.2 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) NAM-associated PF14303.6 GAX16932.1 - 7.5 7.3 10.6 12 6.6 10.6 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Mpv17_PMP22 PF04117.12 GAX16933.1 - 9.7e-20 70.6 0.1 1.5e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Afi1 PF07792.12 GAX16934.1 - 0.22 12.0 5.9 0.28 11.7 5.9 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Holin_BhlA PF10960.8 GAX16934.1 - 1.2 9.1 5.2 0.37 10.8 0.5 2.0 2 0 0 2 2 2 0 BhlA holin family Herpes_US12 PF05363.12 GAX16934.1 - 1.6 9.5 4.9 4.5 8.1 1.2 2.1 1 1 1 2 2 2 0 Herpesvirus US12 family MMtag PF10159.9 GAX16934.1 - 7.3 7.0 9.5 5.3 7.4 1.3 2.1 1 1 0 2 2 2 0 Multiple myeloma tumor-associated UCH PF00443.29 GAX16935.1 - 8e-42 143.5 0.0 1.2e-41 142.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PBP PF01161.20 GAX16935.1 - 2.8e-31 108.5 0.0 6.9e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein UCH_1 PF13423.6 GAX16935.1 - 7.2e-13 48.8 0.6 1.3e-11 44.7 0.6 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ELO PF01151.18 GAX16936.1 - 1.6e-50 171.9 9.1 1.9e-50 171.7 9.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_U4 PF03419.13 GAX16937.1 - 0.056 12.7 3.3 0.13 11.5 1.3 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA LapA_dom PF06305.11 GAX16937.1 - 0.091 12.6 0.1 0.091 12.6 0.1 3.6 2 1 2 4 4 4 0 Lipopolysaccharide assembly protein A domain CIA30 PF08547.12 GAX16938.1 - 6.9e-21 74.9 0.0 9.6e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) zf-CW PF07496.15 GAX16939.1 - 5e-14 52.1 6.5 1.1e-13 50.9 6.5 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger SET PF00856.28 GAX16939.1 - 7e-07 29.8 0.0 7e-07 29.8 0.0 3.6 3 1 0 4 4 4 1 SET domain MBT PF02820.18 GAX16939.1 - 0.2 12.0 2.0 33 4.9 0.0 4.5 5 0 0 5 5 5 0 mbt repeat TRAF_BIRC3_bd PF16673.5 GAX16939.1 - 0.38 10.6 2.7 3.1 7.6 0.2 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF2481 PF10654.9 GAX16940.1 - 0.075 13.0 0.3 0.099 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) DUF2749 PF10907.8 GAX16940.1 - 0.11 12.6 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Transglut_prok PF09017.10 GAX16940.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 Microbial transglutaminase MoeA_N PF03453.17 GAX16941.1 - 1.1e-26 93.5 0.0 2e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 GAX16941.1 - 1e-19 70.6 0.0 3.3e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.15 GAX16941.1 - 4.8e-12 45.9 0.2 1.9e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Lyase_1 PF00206.20 GAX16946.1 - 3.8e-88 295.9 0.0 7.1e-88 295.0 0.0 1.4 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 GAX16946.1 - 1.1e-25 90.2 0.1 2.6e-25 88.9 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF2680 PF10925.8 GAX16946.1 - 0.24 11.5 1.2 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) SNF2_N PF00176.23 GAX16947.1 - 1.2e-24 86.7 0.0 2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX16947.1 - 5.1e-10 39.7 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX16947.1 - 4.5e-05 23.5 0.0 0.00016 21.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GDA1_CD39 PF01150.17 GAX16949.1 - 2.7e-77 260.2 0.0 3.8e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ABC1 PF03109.16 GAX16950.1 - 4.6e-19 68.8 0.0 2e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 ABC1 family Thioredoxin PF00085.20 GAX16952.1 - 1.7e-18 66.5 0.1 3.9e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAX16952.1 - 6.1e-07 29.9 0.5 0.00073 20.0 0.1 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GAX16952.1 - 2.6e-05 23.7 0.0 0.00056 19.3 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 GAX16952.1 - 0.018 15.2 0.0 0.087 13.1 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin Cu2_monoox_C PF03712.15 GAX16953.1 - 5.6e-18 64.9 0.7 9.3e-18 64.2 0.7 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 GAX16953.1 - 1.1e-14 54.8 0.0 2.2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 GAX16953.1 - 1.2e-14 54.6 0.0 3.3e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 DOMON domain AhpC-TSA_2 PF13911.6 GAX16954.1 - 1.8e-14 53.8 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme rhaM PF05336.13 GAX16955.1 - 1.7e-26 92.4 0.9 2.5e-26 91.9 0.9 1.2 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF262 PF03235.14 GAX16957.1 - 0.098 12.8 0.0 0.098 12.8 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF262 Cucumo_2B PF03263.13 GAX16957.1 - 0.1 13.0 0.6 0.27 11.7 0.6 1.7 1 0 0 1 1 1 0 Cucumovirus protein 2B CENP-O PF09496.10 GAX16957.1 - 4.8 7.1 8.6 7.6 6.5 8.0 1.7 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component AA_permease_2 PF13520.6 GAX16958.1 - 6.1e-32 111.0 30.5 8e-32 110.6 30.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAX16959.1 - 2.8e-31 108.8 35.7 3.5e-31 108.5 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAX16959.1 - 2.8e-10 39.4 29.6 6e-10 38.3 29.6 1.5 1 1 0 1 1 1 1 Amino acid permease DUF4191 PF13829.6 GAX16959.1 - 0.0094 15.3 0.7 0.062 12.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4191) DUF2613 PF11021.8 GAX16959.1 - 0.43 10.7 2.7 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) RseC_MucC PF04246.12 GAX16959.1 - 2.9 7.9 8.6 1 9.3 0.4 3.3 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Hydrolase_4 PF12146.8 GAX16960.1 - 2.5e-49 167.7 0.0 3.9e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX16960.1 - 2.2e-11 43.9 0.1 4.4e-09 36.4 0.1 2.8 3 1 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX16960.1 - 7.1e-10 39.9 0.0 8.8e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX16960.1 - 8.4e-06 25.4 0.1 0.0048 16.4 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAX16960.1 - 0.00054 19.8 0.0 3 7.6 0.0 3.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase PF00756.20 GAX16960.1 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 GAX16960.1 - 0.053 13.2 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 GAX16960.1 - 0.057 13.3 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 GAX16960.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein ANF_receptor PF01094.28 GAX16960.1 - 0.12 11.5 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 Receptor family ligand binding region Alpha_kinase PF02816.18 GAX16961.1 - 3.8e-43 147.7 0.0 5.4e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Agenet PF05641.12 GAX16961.1 - 0.0037 17.7 0.0 0.0093 16.4 0.0 1.7 1 0 0 1 1 1 1 Agenet domain Tudor_3 PF18115.1 GAX16961.1 - 0.009 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TPR_14 PF13428.6 GAX16961.1 - 0.047 14.5 1.6 0.62 11.0 0.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX16961.1 - 1.4 9.5 5.4 3.1 8.4 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Hist_deacetyl PF00850.19 GAX16962.1 - 1.9e-65 221.3 0.0 3.6e-64 217.2 0.0 2.2 2 0 0 2 2 2 1 Histone deacetylase domain Ank_2 PF12796.7 GAX16962.1 - 6.5e-13 49.1 0.0 6.8e-12 45.8 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX16962.1 - 7.7e-12 45.5 0.2 6.7e-06 26.5 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Myb_DNA-binding PF00249.31 GAX16962.1 - 2e-10 40.7 0.3 3.5e-10 39.9 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ank_5 PF13857.6 GAX16962.1 - 2.8e-10 40.3 0.1 6.8e-08 32.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX16962.1 - 7.4e-10 38.8 0.2 0.032 14.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 GAX16962.1 - 8.6e-10 38.0 0.0 0.00097 19.4 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Myb_DNA-bind_6 PF13921.6 GAX16962.1 - 0.031 14.5 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX16962.1 - 0.036 14.0 0.3 0.084 12.8 0.3 1.6 1 0 0 1 1 1 0 Myb DNA-binding like GatB_N PF02934.15 GAX16963.1 - 7.9e-88 294.4 0.0 1.1e-87 294.0 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 GAX16963.1 - 3.3e-19 69.2 0.1 7.2e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 GatB domain PT PF04886.12 GAX16964.1 - 0.0022 17.5 8.0 0.0022 17.5 8.0 4.3 1 1 2 3 3 3 1 PT repeat DUF4381 PF14316.6 GAX16964.1 - 0.026 14.8 0.2 0.069 13.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ribosomal_S2 PF00318.20 GAX16964.1 - 0.079 12.2 0.1 0.26 10.5 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein S2 CbtA PF09490.10 GAX16964.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) PP2C PF00481.21 GAX16965.1 - 4.8e-49 167.3 0.1 6e-49 167.0 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3782 PF12644.7 GAX16966.1 - 0.044 13.9 3.9 0.31 11.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) Pro_isomerase PF00160.21 GAX16967.1 - 9.3e-43 146.2 0.0 1.9e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_13 PF18335.1 GAX16968.1 - 7.9 6.4 5.7 24 4.8 0.4 3.0 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain Bromodomain PF00439.25 GAX16969.1 - 9e-64 211.6 1.1 1.6e-21 76.1 0.1 3.7 3 0 0 3 3 3 3 Bromodomain SNF2_N PF00176.23 GAX16969.1 - 4.1e-56 190.2 0.1 8e-56 189.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX16969.1 - 5.2e-20 71.8 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 GAX16969.1 - 4.5e-15 55.3 1.0 7e-09 35.5 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HMG_box PF00505.19 GAX16969.1 - 4.8e-12 46.1 1.8 1.6e-11 44.5 1.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box ResIII PF04851.15 GAX16969.1 - 1.8e-07 31.3 0.0 6.3e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box_2 PF09011.10 GAX16969.1 - 1.1e-06 29.1 1.0 4.4e-06 27.2 1.0 2.1 1 0 0 1 1 1 1 HMG-box domain PHD PF00628.29 GAX16969.1 - 1.6e-05 24.7 12.8 3.5e-05 23.6 12.8 1.6 1 0 0 1 1 1 1 PHD-finger HDA2-3 PF11496.8 GAX16969.1 - 2.8e-05 23.4 0.1 0.00019 20.7 0.0 2.5 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 CHDNT PF08073.12 GAX16969.1 - 0.003 17.5 0.0 0.013 15.5 0.0 2.1 1 0 0 1 1 1 1 CHDNT (NUC034) domain DEAD PF00270.29 GAX16969.1 - 0.0036 17.1 0.0 0.013 15.3 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAX16969.1 - 0.009 15.2 0.0 0.025 13.8 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PDZ_6 PF17820.1 GAX16969.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PHF5 PF03660.14 GAX16969.1 - 0.51 10.6 3.0 1.6 9.0 3.0 1.8 1 0 0 1 1 1 0 PHF5-like protein DENN PF02141.21 GAX16970.1 - 2.3e-44 151.6 6.7 3.9e-44 150.8 6.7 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAX16970.1 - 4.1e-17 62.7 1.9 1.6e-16 60.8 0.9 2.4 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 GAX16970.1 - 2.6e-08 33.7 2.9 6.1e-08 32.5 2.9 1.7 1 0 0 1 1 1 1 dDENN domain PPR PF01535.20 GAX16970.1 - 0.00045 20.3 0.1 0.0011 19.0 0.1 1.7 1 0 0 1 1 1 1 PPR repeat zinc_ribbon_9 PF14369.6 GAX16970.1 - 0.091 13.0 3.3 2.8 8.3 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon SPA PF08616.10 GAX16970.1 - 0.098 12.6 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis PPR_1 PF12854.7 GAX16970.1 - 0.12 12.1 0.4 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 PPR repeat Abhydrolase_2 PF02230.16 GAX16971.1 - 2.1e-05 24.4 0.0 0.00069 19.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAX16971.1 - 0.0063 17.1 0.2 0.0084 16.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAX16971.1 - 0.0069 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX16971.1 - 0.024 14.1 0.2 2 7.9 0.0 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF2235 PF09994.9 GAX16971.1 - 0.14 11.4 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) PseudoU_synth_2 PF00849.22 GAX16972.1 - 2.4e-26 92.7 0.0 9.4e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 RNA pseudouridylate synthase PQQ_2 PF13360.6 GAX16972.1 - 0.03 13.9 0.0 0.098 12.2 0.0 1.8 2 1 0 2 2 2 0 PQQ-like domain DUF2651 PF10852.8 GAX16972.1 - 0.19 12.3 1.9 0.4 11.3 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) TRIC PF05197.13 GAX16973.1 - 3.8e-08 33.1 0.3 5.5e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 GAX16973.1 - 0.011 15.6 0.6 0.029 14.3 0.6 1.7 1 0 0 1 1 1 0 UPF0126 domain PUF PF00806.19 GAX16974.1 - 3.4e-50 165.0 10.7 2.5e-06 26.9 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.11 GAX16974.1 - 0.23 11.8 0.6 9.2 6.6 0.0 3.7 2 2 0 2 2 2 0 CPL (NUC119) domain GTP_EFTU PF00009.27 GAX16975.1 - 1.6e-66 223.6 0.0 2.4e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAX16975.1 - 2.5e-42 143.5 0.1 4.6e-42 142.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 GAX16975.1 - 9.6e-35 118.5 0.1 2.3e-34 117.3 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAX16975.1 - 2.9e-25 88.1 0.0 7.3e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX16975.1 - 3.1e-16 59.5 3.1 5e-16 58.8 1.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAX16975.1 - 3.4e-07 30.1 0.0 7.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAX16975.1 - 0.00065 19.8 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAX16975.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 AIG1 family TDP43_N PF18694.1 GAX16975.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain CK_II_beta PF01214.18 GAX16976.1 - 4.3e-28 98.3 0.0 6.6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FYVE PF01363.21 GAX16979.1 - 1.1e-10 41.5 12.0 1.7e-10 40.9 12.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger Ank_2 PF12796.7 GAX16979.1 - 0.00062 20.3 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX16979.1 - 0.0019 18.7 0.0 0.27 11.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX16979.1 - 0.012 16.1 0.1 0.23 12.1 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 GAX16979.1 - 0.049 14.0 0.0 4.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) FYVE_2 PF02318.16 GAX16979.1 - 0.2 11.9 7.3 0.4 10.9 7.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 GAX16980.1 - 6.1e-12 45.5 9.1 6.1e-12 45.5 9.1 2.6 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 GAX16980.1 - 1e-06 28.5 22.6 1e-06 28.5 22.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 GAX16980.1 - 0.00028 21.4 0.0 1.5 9.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX16980.1 - 0.00097 19.4 0.0 0.42 11.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 GAX16980.1 - 0.01 16.4 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FYVE PF01363.21 GAX16981.1 - 6.3e-07 29.4 8.7 6.3e-07 29.4 8.7 2.8 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 GAX16981.1 - 2.8e-06 27.1 25.0 2.8e-06 27.1 25.0 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 GAX16981.1 - 0.00039 20.7 0.0 0.048 14.0 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX16981.1 - 0.0031 18.1 0.0 0.0056 17.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX16981.1 - 0.0061 17.0 0.0 0.78 10.5 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 GAX16981.1 - 0.035 14.7 0.0 0.67 10.6 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF155 PF02582.14 GAX16982.1 - 1.7e-40 139.0 0.3 2.4e-40 138.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Na_H_Exchanger PF00999.21 GAX16983.1 - 8e-45 153.3 21.2 2.1e-42 145.3 20.3 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family GTP_EFTU PF00009.27 GAX16984.1 - 2.6e-52 177.2 0.2 3e-52 177.0 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAX16984.1 - 0.0017 18.4 0.1 0.0037 17.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAX16984.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MobB PF03205.14 GAX16984.1 - 0.025 14.5 0.3 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B EFG_IV PF03764.18 GAX16985.1 - 3e-37 127.1 0.4 3.8e-36 123.5 0.1 2.6 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.6 GAX16985.1 - 2.3e-32 110.9 0.1 5.2e-32 109.8 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAX16985.1 - 3.6e-25 87.8 0.1 1.9e-24 85.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX16985.1 - 2.4e-11 43.8 0.4 3e-10 40.4 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAX16985.1 - 1.8e-08 34.3 0.0 5.3e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SBDS_C PF09377.10 GAX16985.1 - 0.0035 17.3 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 SBDS protein C-terminal domain NFACT-R_1 PF05670.13 GAX16986.1 - 2.5e-33 115.0 0.0 4.6e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF4340 PF14238.6 GAX16986.1 - 0.15 12.1 1.9 0.24 11.4 0.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4340) WD40 PF00400.32 GAX16987.1 - 2e-15 56.9 13.9 0.0023 18.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX16987.1 - 1.2e-14 54.4 0.0 0.14 12.5 0.1 5.6 4 2 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX16987.1 - 5.8e-05 22.2 0.2 0.59 9.0 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAX16987.1 - 0.0039 17.1 0.0 3.5 7.7 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 GAX16987.1 - 0.049 13.0 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 GAX16987.1 - 0.06 11.3 0.0 0.14 10.1 0.0 1.5 1 1 0 1 1 1 0 IKI3 family SGL PF08450.12 GAX16987.1 - 0.062 12.9 0.1 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region eIF2A PF08662.11 GAX16987.1 - 0.15 11.9 0.0 2.5 7.9 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Guanylate_kin PF00625.21 GAX16988.1 - 9.2e-51 172.1 0.0 1.1e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 GAX16988.1 - 0.00029 21.0 0.0 0.00075 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAX16988.1 - 0.0086 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 GAX16988.1 - 0.016 15.8 1.0 0.27 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX16988.1 - 0.05 14.0 0.0 0.064 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAX16988.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX16988.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Glyco_hydro_31 PF01055.26 GAX16989.1 - 3.9e-90 303.2 4.1 4.3e-90 303.0 3.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAX16989.1 - 3.2e-22 78.6 1.2 3.8e-21 75.2 0.1 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like PTPLA PF04387.14 GAX16990.1 - 4e-39 134.0 6.6 7.2e-39 133.2 6.6 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Sua5_yciO_yrdC PF01300.18 GAX16991.1 - 2.4e-42 144.4 0.0 3.4e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 GAX16991.1 - 1.2e-13 51.8 0.0 2.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding PseudoU_synth_2 PF00849.22 GAX16992.1 - 1.6e-22 80.3 0.0 3.2e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase PsbP PF01789.16 GAX16993.1 - 1.9e-15 57.3 0.2 2.4e-15 57.0 0.2 1.1 1 0 0 1 1 1 1 PsbP ubiquitin PF00240.23 GAX16994.1 - 1.9e-05 24.3 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DnaJ PF00226.31 GAX16995.1 - 2.6e-11 43.5 0.0 6.7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain IGR PF09597.10 GAX16995.1 - 0.024 14.7 0.5 11 6.3 0.1 3.1 2 1 0 2 2 2 0 IGR protein motif TatD_DNase PF01026.21 GAX16996.1 - 2.2e-42 145.2 0.0 2.7e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Defensin_5 PF18251.1 GAX16996.1 - 0.07 13.2 4.2 0.56 10.3 0.2 2.4 2 0 0 2 2 2 0 Fungal defensin Copsin p450 PF00067.22 GAX16997.1 - 2.3e-60 204.6 0.1 3.1e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cas1_AcylT PF07779.12 GAX16998.1 - 3.2e-60 204.4 20.8 1.7e-59 202.0 20.8 1.8 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Zn_peptidase_2 PF04298.12 GAX16998.1 - 0.12 11.7 1.8 3.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Putative neutral zinc metallopeptidase DctQ PF04290.12 GAX16998.1 - 0.9 9.5 14.1 3.4 7.6 0.0 4.4 3 1 1 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2069 PF09842.9 GAX16998.1 - 3.9 7.7 10.8 4.7 7.5 0.0 4.6 4 2 0 4 4 4 0 Predicted membrane protein (DUF2069) HNH_3 PF13392.6 GAX16999.1 - 4.7e-05 23.1 4.4 0.00044 19.9 0.3 2.6 2 0 0 2 2 2 2 HNH endonuclease DUF4909 PF16253.5 GAX16999.1 - 0.053 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) KH_6 PF15985.5 GAX17000.1 - 3.9e-10 39.9 0.0 7.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 GAX17000.1 - 2.7e-09 36.7 1.6 2.4e-08 33.6 1.6 2.4 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PIP5K PF01504.18 GAX17001.1 - 2e-40 138.8 0.5 1.7e-31 109.5 0.0 2.9 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 GAX17001.1 - 2.5e-27 95.7 0.0 5e-27 94.7 0.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 GAX17001.1 - 8.8e-13 48.2 16.3 8.8e-13 48.2 16.3 2.2 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 GAX17001.1 - 0.00025 21.2 6.2 0.00025 21.2 6.2 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger DUF4527 PF15030.6 GAX17001.1 - 0.0037 16.7 0.2 0.0089 15.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4527) GST_N_3 PF13417.6 GAX17002.1 - 1.9e-13 50.6 0.0 3.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX17002.1 - 8.7e-13 48.4 0.0 2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAX17002.1 - 1.6e-09 37.8 0.0 3.8e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX17002.1 - 1.6e-06 28.0 0.0 2.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX17002.1 - 1.1e-05 25.6 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAX17002.1 - 0.00017 21.8 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAX17002.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Complex1_LYR PF05347.15 GAX17003.1 - 6.6e-10 38.9 0.2 1.5e-09 37.7 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAX17003.1 - 0.0015 19.3 0.4 0.0023 18.6 0.4 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Exo70 PF03081.15 GAX17005.1 - 5.6e-39 134.3 1.3 6.5e-39 134.0 0.3 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit COG6 PF06419.11 GAX17005.1 - 0.076 11.2 4.1 2.4 6.3 0.2 2.6 2 1 0 2 2 2 0 Conserved oligomeric complex COG6 DUF948 PF06103.11 GAX17005.1 - 0.11 12.7 3.7 1 9.6 0.0 3.9 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF5576 PF17739.1 GAX17006.1 - 0.031 14.4 0.1 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5576) HEAT_2 PF13646.6 GAX17006.1 - 0.047 14.1 0.5 0.72 10.3 0.1 2.9 3 0 0 3 3 3 0 HEAT repeats Abhydrolase_1 PF00561.20 GAX17009.1 - 0.01 15.5 0.0 0.027 14.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 GAX17009.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 GAX17010.1 - 7e-05 23.5 0.0 0.00024 21.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX17010.1 - 0.0015 18.2 0.0 0.0048 16.6 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX17010.1 - 0.013 15.0 0.0 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 GAX17010.1 - 0.046 13.3 0.4 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 GAX17010.1 - 0.094 12.0 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 GAX17010.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF676 PF05057.14 GAX17010.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Dicty_CTDC PF00526.18 GAX17011.1 - 0.006 16.5 2.3 0.006 16.5 2.3 7.4 6 1 0 6 6 6 5 Dictyostelium (slime mold) repeat Trigger_C PF05698.14 GAX17012.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus HA2 PF04408.23 GAX17013.1 - 5.6e-17 62.0 0.0 5.6e-17 62.0 0.0 3.6 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX17013.1 - 9.5e-11 41.9 0.0 3e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX17013.1 - 4.3e-10 39.9 0.0 3.6e-09 37.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX17013.1 - 0.00018 21.3 1.9 0.00029 20.7 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX17013.1 - 0.00088 19.6 2.1 0.0023 18.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAX17013.1 - 0.024 14.4 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX17013.1 - 0.046 14.2 0.0 0.046 14.2 0.0 3.5 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 GAX17013.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF1382 PF07131.11 GAX17013.1 - 0.59 10.2 2.5 1.8 8.6 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) ABC_tran PF00005.27 GAX17013.1 - 1.7 9.2 5.0 2.1 8.8 0.0 3.3 3 1 0 3 3 3 0 ABC transporter MFS_3 PF05977.13 GAX17014.1 - 1e-21 77.0 14.0 1.3e-21 76.6 14.0 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 GAX17014.1 - 1.3e-19 70.4 26.4 1.8e-19 69.9 26.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Mito_carr PF00153.27 GAX17015.1 - 4.6e-41 138.7 2.0 2.5e-20 72.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1772 PF08592.11 GAX17015.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) WW PF00397.26 GAX17016.1 - 5e-16 58.5 9.2 2e-07 30.9 0.4 2.5 2 0 0 2 2 2 2 WW domain WW PF00397.26 GAX17017.1 - 2.7e-22 78.6 16.5 1.5e-07 31.4 1.0 3.6 3 0 0 3 3 3 3 WW domain Glyco_hyd_101C PF17451.2 GAX17017.1 - 5.2e-06 26.7 3.2 0.5 10.7 0.0 3.7 3 1 0 3 3 3 3 Glycosyl hydrolase 101 beta sandwich domain PQQ_2 PF13360.6 GAX17017.1 - 0.00052 19.7 0.2 0.0022 17.6 0.1 1.9 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 GAX17017.1 - 0.046 13.6 0.3 6.9 6.8 0.1 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat DDE_Tnp_IS66_C PF13817.6 GAX17017.1 - 0.08 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 IS66 C-terminal element Ysc84 PF04366.12 GAX17018.1 - 7.8e-20 70.9 0.2 1.1e-19 70.5 0.2 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ysc84 PF04366.12 GAX17019.1 - 7.6e-21 74.2 0.2 1.1e-20 73.7 0.2 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ysc84 PF04366.12 GAX17020.1 - 2.1e-23 82.5 0.2 2.7e-23 82.1 0.2 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator PH PF00169.29 GAX17021.1 - 8.1e-10 39.2 0.0 3.8e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 GAX17021.1 - 0.0024 18.1 0.0 0.0058 16.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CCDC-167 PF15188.6 GAX17021.1 - 0.017 15.5 1.8 0.017 15.5 1.8 4.3 4 2 2 6 6 6 0 Coiled-coil domain-containing protein 167 Csm1_N PF18504.1 GAX17021.1 - 0.89 9.9 10.8 1.1 9.6 3.9 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 GAX17021.1 - 4.1 5.2 7.7 7.3 4.4 7.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GTP_EFTU PF00009.27 GAX17022.1 - 8.6e-43 146.1 0.1 1.5e-42 145.4 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAX17022.1 - 3.6e-10 40.1 0.1 9.3e-10 38.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 GAX17022.1 - 1.9e-05 25.0 0.4 8.9e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 GAX17022.1 - 0.00013 22.0 0.1 0.0011 19.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase HEAT_2 PF13646.6 GAX17023.1 - 0.00067 20.0 1.7 0.37 11.2 0.0 4.0 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 GAX17023.1 - 0.0013 18.8 5.7 0.31 11.4 0.1 4.8 5 0 0 5 5 5 1 HEAT repeat MMS19_N PF14500.6 GAX17023.1 - 0.029 14.0 1.5 0.25 10.9 0.1 2.7 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF5523 PF17661.1 GAX17023.1 - 0.077 12.7 14.1 0.12 12.0 14.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4670 PF15709.5 GAX17023.1 - 0.13 11.6 26.4 0.19 11.0 26.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) SpoIIE PF07228.12 GAX17024.1 - 6.1e-09 36.1 0.0 9.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) WW PF00397.26 GAX17024.1 - 5.2e-06 26.4 0.1 1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 WW domain PP2C PF00481.21 GAX17024.1 - 5.7e-06 26.2 0.1 0.0042 16.8 0.1 2.6 2 0 0 2 2 2 2 Protein phosphatase 2C DUF2076 PF09849.9 GAX17024.1 - 0.00057 20.0 1.6 0.0019 18.3 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) PP2C_2 PF13672.6 GAX17024.1 - 0.0086 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SGS PF05002.15 GAX17025.1 - 5.8e-32 109.6 5.5 1.6e-31 108.2 5.5 1.8 1 0 0 1 1 1 1 SGS domain TPR_2 PF07719.17 GAX17025.1 - 1.6e-11 43.4 6.1 0.0043 17.1 0.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.16 GAX17025.1 - 4.3e-10 40.5 0.1 8.9e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 GAX17025.1 - 9.2e-09 34.8 3.7 0.01 15.6 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX17025.1 - 2.4e-06 27.7 9.4 1.4e-05 25.3 0.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX17025.1 - 0.0003 21.4 5.1 0.15 12.8 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17025.1 - 0.018 15.2 2.7 1.7 9.0 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17025.1 - 0.018 15.0 2.0 0.11 12.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17025.1 - 0.034 14.9 6.7 11 7.2 1.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat XS PF03468.14 GAX17025.1 - 0.037 14.3 0.3 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 XS domain DUF2057 PF09829.9 GAX17025.1 - 7.3 6.7 13.1 0.16 12.2 1.3 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) Polyketide_cyc2 PF10604.9 GAX17026.1 - 2.9e-10 40.6 0.1 4.1e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX17026.1 - 1.2e-05 25.5 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4336 PF14234.6 GAX17028.1 - 5e-117 390.6 0.0 6.1e-117 390.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) RRM_1 PF00076.22 GAX17029.1 - 1.1e-26 92.4 0.1 6.8e-14 51.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX17029.1 - 6.1e-06 26.3 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 GAX17029.1 - 0.003 17.4 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif Peptidase_M17 PF00883.21 GAX17030.1 - 4.3e-109 364.5 0.4 6.4e-109 364.0 0.4 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF1177 PF06675.11 GAX17030.1 - 0.12 11.2 0.2 0.18 10.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) Pyridoxal_deC PF00282.19 GAX17031.1 - 6.2e-28 97.6 0.0 1.3e-27 96.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAX17031.1 - 1.5e-05 24.1 0.0 3.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAX17031.1 - 0.0025 17.0 0.0 0.011 14.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 GAX17031.1 - 0.082 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Aquarius_N PF16399.5 GAX17032.1 - 6.1e-90 302.4 0.0 9.3e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 GAX17032.1 - 5.2e-31 107.8 0.0 7.9e-30 104.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAX17032.1 - 4e-27 95.7 0.0 8.6e-27 94.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX17032.1 - 1.4e-07 31.9 0.0 1.2e-06 28.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX17032.1 - 1.5e-07 31.3 0.0 0.00026 20.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 GAX17032.1 - 0.00083 19.4 0.0 0.0028 17.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 GAX17032.1 - 0.004 16.9 0.0 0.088 12.6 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 GAX17032.1 - 0.0091 15.5 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Parvo_NS1 PF01057.17 GAX17032.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 GAX17032.1 - 0.013 15.8 0.1 0.12 12.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 GAX17032.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 GAX17032.1 - 0.039 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 GAX17032.1 - 0.078 12.5 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NDUFA12 PF05071.16 GAX17033.1 - 5.5e-17 62.4 1.0 5.5e-17 62.4 1.0 2.1 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Amidohydro_1 PF01979.20 GAX17034.1 - 1.8e-31 109.7 0.1 3.9e-31 108.6 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAX17034.1 - 3.8e-13 49.7 2.2 7.9e-06 25.6 0.4 3.1 2 1 0 2 2 2 2 Amidohydrolase family Cytochrom_C1 PF02167.15 GAX17035.1 - 4.4e-87 291.4 0.0 5.2e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GAX17035.1 - 0.0029 17.9 0.0 0.008 16.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III CLLAC PF15675.5 GAX17037.1 - 0.044 13.4 1.5 0.1 12.2 1.5 1.6 1 0 0 1 1 1 0 CLLAC-motif containing domain Acyl_transf_3 PF01757.22 GAX17038.1 - 5.9e-23 81.5 28.1 5.9e-23 81.5 28.1 1.9 2 0 0 2 2 2 1 Acyltransferase family DUF2417 PF10329.9 GAX17038.1 - 0.078 12.4 0.1 0.078 12.4 0.1 2.6 2 1 0 2 2 2 0 Region of unknown function (DUF2417) FGE-sulfatase PF03781.16 GAX17039.1 - 4.4e-30 105.1 3.3 8.2e-30 104.2 3.3 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_23 PF13489.6 GAX17039.1 - 1.3e-12 47.9 0.0 2.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX17039.1 - 7.4e-09 35.6 0.0 4.6e-07 29.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX17039.1 - 3.5e-08 34.1 0.0 4.9e-05 24.0 0.0 2.7 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAX17039.1 - 5.8e-08 33.4 0.0 8.1e-07 29.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX17039.1 - 7.2e-08 33.0 0.0 1.6e-06 28.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 GAX17039.1 - 2.6e-06 28.0 0.1 5.7e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 DinB superfamily MTS PF05175.14 GAX17039.1 - 0.0034 17.0 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 GAX17039.1 - 0.087 11.9 0.0 4.3 6.4 0.0 2.7 1 1 0 1 1 1 0 DREV methyltransferase TB PF00683.17 GAX17040.1 - 4.4 7.1 10.8 6.4 6.6 0.0 4.1 4 0 0 4 4 4 0 TB domain PPR_2 PF13041.6 GAX17041.1 - 4.6e-35 119.6 3.6 5.9e-06 26.4 0.0 9.5 7 2 2 9 9 9 7 PPR repeat family PPR_1 PF12854.7 GAX17041.1 - 2.1e-29 100.9 14.4 0.00026 20.6 0.0 12.1 12 0 0 12 12 12 9 PPR repeat PPR_3 PF13812.6 GAX17041.1 - 1.2e-25 89.3 0.3 0.0009 19.3 0.0 8.7 6 2 3 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX17041.1 - 4e-14 52.5 1.4 6.4e-08 32.2 0.0 4.5 1 1 4 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX17041.1 - 7e-09 35.3 32.4 0.017 15.3 0.1 11.9 14 1 0 14 14 14 3 PPR repeat YbfN PF13982.6 GAX17041.1 - 0.078 13.3 0.2 12 6.3 0.0 3.1 3 0 0 3 3 3 0 YbfN-like lipoprotein TPR_14 PF13428.6 GAX17041.1 - 0.081 13.8 9.4 1.1 10.2 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MerR_1 PF13411.6 GAX17041.1 - 0.13 12.4 0.3 41 4.4 0.0 2.9 3 0 0 3 3 3 0 MerR HTH family regulatory protein FAD_binding_4 PF01565.23 GAX17042.1 - 2.5e-09 37.0 0.7 4.9e-09 36.0 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 GAX17042.1 - 0.0099 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase HlyD_3 PF13437.6 GAX17042.1 - 0.067 13.9 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein DUF4936 PF16290.5 GAX17042.1 - 0.17 12.6 0.0 0.47 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) FAD_binding_4 PF01565.23 GAX17043.1 - 3.4e-11 43.1 0.6 6.6e-11 42.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 GAX17043.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 GAX17044.1 - 1.1e-07 31.7 0.1 2.1e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.23 GAX17045.1 - 1.4e-09 37.8 0.9 2.8e-09 36.8 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 GAX17045.1 - 4.1e-05 23.5 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DUF4936 PF16290.5 GAX17045.1 - 0.095 13.4 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) zf-C2H2_jaz PF12171.8 GAX17046.1 - 6e-05 23.2 2.4 0.0058 16.9 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding SH3_2 PF07653.17 GAX17046.1 - 0.0067 16.1 0.1 0.033 13.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain zf-met PF12874.7 GAX17046.1 - 0.0081 16.5 3.3 0.038 14.4 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAX17046.1 - 0.089 13.7 5.6 0.66 11.0 0.2 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger SH3_1 PF00018.28 GAX17046.1 - 0.14 11.8 0.5 0.62 9.7 0.0 2.4 3 0 0 3 3 3 0 SH3 domain FYVE PF01363.21 GAX17046.1 - 0.3 11.2 3.9 0.84 9.8 3.9 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-C2H2 PF00096.26 GAX17046.1 - 1.6 9.4 9.7 0.34 11.5 0.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type MORN PF02493.20 GAX17047.1 - 0.00098 18.9 7.0 0.019 14.8 6.3 2.7 2 0 0 2 2 2 1 MORN repeat ESSS PF10183.9 GAX17048.1 - 0.0039 17.4 0.3 0.0061 16.8 0.0 1.6 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NOA36 PF06524.12 GAX17048.1 - 0.21 10.9 5.5 0.23 10.8 5.5 1.1 1 0 0 1 1 1 0 NOA36 protein Spb1_C PF07780.12 GAX17049.1 - 2.8e-52 177.4 14.9 2.8e-52 177.4 14.9 4.5 3 2 2 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.19 GAX17049.1 - 4.5e-46 157.2 0.0 1.2e-45 155.7 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 GAX17049.1 - 3.9e-27 95.1 12.4 3.9e-27 95.1 12.4 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Thioredoxin PF00085.20 GAX17050.1 - 8.5e-17 61.0 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX17050.1 - 2.1e-11 44.0 0.0 1.3e-08 35.0 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX17050.1 - 4.1e-07 30.4 0.0 8.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 GAX17050.1 - 2e-05 24.6 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX17050.1 - 2.3e-05 24.5 0.1 7.9e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.6 GAX17050.1 - 3.6e-05 23.7 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 GAX17050.1 - 6.3e-05 22.9 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GAX17050.1 - 0.0005 19.8 0.1 0.0026 17.5 0.0 2.2 2 1 1 3 3 3 1 Redoxin Thioredoxin_5 PF13743.6 GAX17050.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF4533 PF15047.6 GAX17050.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Bromodomain PF00439.25 GAX17051.1 - 2.3e-21 75.7 0.2 1e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 GAX17051.1 - 7.1e-06 26.1 0.6 1.1e-05 25.5 0.6 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Cauli_DNA-bind PF03310.13 GAX17051.1 - 0.025 14.6 0.9 0.048 13.7 0.9 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein UPF0489 PF12640.7 GAX17052.1 - 1.1e-27 97.4 3.6 3.1e-27 96.0 3.6 1.8 1 1 0 1 1 1 1 UPF0489 domain APS_kinase PF01583.20 GAX17053.1 - 6e-58 195.2 0.0 1.1e-57 194.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 GAX17053.1 - 6.2e-47 159.8 0.0 1e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 GAX17053.1 - 5.3e-44 149.9 0.0 8e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 GAX17053.1 - 9.9e-36 122.8 0.0 9e-35 119.7 0.0 2.6 3 0 0 3 3 3 1 PUA-like domain AAA_33 PF13671.6 GAX17053.1 - 9.3e-06 25.9 0.0 3.6e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX17053.1 - 0.00085 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 GAX17053.1 - 0.001 19.6 0.1 0.0048 17.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX17053.1 - 0.044 14.1 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX17053.1 - 0.044 14.0 0.5 0.2 11.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX17053.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 GAX17053.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 GAX17053.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FA_desaturase PF00487.24 GAX17054.1 - 7.6e-22 78.4 13.5 1.3e-21 77.6 13.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase zf-RING_6 PF14835.6 GAX17055.1 - 1.1e-07 31.6 5.9 2.1e-07 30.7 5.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 GAX17055.1 - 7.2e-06 25.8 18.2 7.2e-06 25.8 18.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX17055.1 - 9.3e-06 25.4 16.9 9.3e-06 25.4 16.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX17055.1 - 1.7e-05 24.8 13.2 4.1e-05 23.5 13.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 GAX17055.1 - 0.002 18.2 10.7 0.0037 17.4 10.7 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 GAX17055.1 - 0.0044 17.3 16.0 0.01 16.1 16.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAX17055.1 - 0.0055 16.6 17.1 0.0055 16.6 17.1 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX17055.1 - 0.0057 16.5 13.8 0.01 15.7 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAX17055.1 - 0.0058 16.8 16.4 0.0058 16.8 16.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 GAX17055.1 - 0.067 13.0 7.7 0.16 11.8 7.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 GAX17055.1 - 0.98 9.8 14.4 0.3 11.4 10.5 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAX17055.1 - 1.8 8.5 16.8 1 9.3 14.5 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF938 PF06080.12 GAX17057.1 - 8.1e-45 153.1 0.0 9.9e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Myosin_head PF00063.21 GAX17058.1 - 2e-212 707.1 0.0 4.2e-212 706.1 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 GAX17058.1 - 4.7e-08 32.1 22.4 0.026 14.3 0.1 5.8 4 1 1 5 5 5 5 IQ calmodulin-binding motif BLOC1_2 PF10046.9 GAX17058.1 - 0.55 10.6 18.9 0.47 10.8 10.5 3.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 GAX17058.1 - 0.74 8.6 33.0 0.05 12.5 15.7 2.9 2 0 0 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 GAX17058.1 - 6.5 7.2 12.6 1.6 9.2 1.9 4.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Fasciclin PF02469.22 GAX17059.1 - 3.6e-11 43.4 0.0 4.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Peptidase_M17 PF00883.21 GAX17060.1 - 3.5e-109 364.9 1.0 5.4e-109 364.2 1.0 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 GAX17060.1 - 2.9e-08 33.6 0.0 8.8e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Sof1 PF04158.14 GAX17060.1 - 0.029 14.6 0.0 0.21 11.9 0.0 2.5 4 0 0 4 4 4 0 Sof1-like domain RRM_1 PF00076.22 GAX17061.1 - 3.7e-18 65.1 0.0 5.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX17061.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 GAX17061.1 - 0.059 13.1 0.4 0.096 12.4 0.4 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain Metallophos PF00149.28 GAX17062.1 - 6.7e-25 88.8 0.2 1.3e-24 87.8 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BAR_3 PF16746.5 GAX17062.1 - 0.089 12.5 0.9 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 BAR domain of APPL family Ribosomal_L38e PF01781.18 GAX17063.1 - 1.5e-32 111.5 1.4 1.6e-32 111.4 1.4 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family GHL13 PF14883.6 GAX17063.1 - 0.067 12.2 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 SQS_PSY PF00494.19 GAX17065.1 - 3.1e-60 203.9 0.9 6.8e-60 202.8 0.7 1.6 2 0 0 2 2 2 1 Squalene/phytoene synthase Exotox-A_cataly PF09009.10 GAX17065.1 - 0.0076 16.0 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Exotoxin A catalytic FKBP_C PF00254.28 GAX17066.1 - 3.2e-28 97.9 0.0 3.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PC4 PF02229.16 GAX17067.1 - 3.9e-24 84.0 0.1 5.6e-24 83.5 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Alg6_Alg8 PF03155.15 GAX17068.1 - 1.4e-98 331.0 28.3 1.8e-98 330.6 28.3 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family zf-HC5HC2H_2 PF13832.6 GAX17069.1 - 2e-21 76.2 42.5 3.2e-12 46.6 6.6 5.2 5 0 0 5 5 5 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAX17069.1 - 4.1e-15 55.8 16.2 2.7e-11 43.6 2.2 5.6 4 2 1 5 5 5 3 PHD-like zinc-binding domain PHD_2 PF13831.6 GAX17069.1 - 5.8e-10 38.5 4.7 5.8e-10 38.5 4.7 4.3 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 GAX17069.1 - 2.5e-09 36.9 5.1 2.5e-09 36.9 5.1 5.1 6 0 0 6 6 6 2 PHD-finger C1_1 PF00130.22 GAX17069.1 - 0.011 15.6 0.9 0.011 15.6 0.9 6.0 5 2 1 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_2 PF12796.7 GAX17071.1 - 4e-21 75.4 0.2 1.7e-10 41.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX17071.1 - 4.9e-15 55.7 0.1 0.00016 22.2 0.0 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX17071.1 - 1.4e-14 53.9 0.3 1.2e-07 31.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 GAX17071.1 - 7.4e-14 51.6 18.9 1.1e-13 51.0 18.9 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 GAX17071.1 - 1.3e-13 49.7 0.0 0.00083 19.6 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAX17071.1 - 3.7e-13 49.3 0.1 0.00011 22.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ion_trans_2 PF07885.16 GAX17071.1 - 3.5e-10 39.7 11.8 3.5e-10 39.7 11.8 2.2 2 1 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 GAX17071.1 - 1.3e-07 31.6 0.0 3.8e-06 26.9 0.0 2.6 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4618 PF15397.6 GAX17071.1 - 0.089 12.2 0.2 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) IRK PF01007.20 GAX17071.1 - 8.2 6.2 10.9 0.41 10.4 4.8 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF3464 PF11947.8 GAX17072.1 - 4.6e-37 127.1 0.2 1.1e-36 125.9 0.2 1.7 1 1 0 1 1 1 1 Photosynthesis affected mutant 68 DUF1772 PF08592.11 GAX17072.1 - 0.55 10.5 2.5 1.3 9.4 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Gasdermin PF04598.12 GAX17073.1 - 0.03 13.7 0.1 0.034 13.6 0.1 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain GlcNAc PF11397.8 GAX17074.1 - 3.7e-58 197.7 1.5 6.4e-46 157.4 0.7 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) MatE PF01554.18 GAX17075.1 - 5.7e-20 71.6 23.2 2.6e-11 43.4 0.8 3.6 3 1 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 GAX17075.1 - 1.1e-10 41.7 7.9 1.1e-10 41.7 7.9 3.7 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF1270 PF06900.11 GAX17075.1 - 0.034 14.5 1.8 0.14 12.6 1.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Serpin PF00079.20 GAX17076.1 - 3.8e-57 194.3 0.0 5.4e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) LETM1 PF07766.13 GAX17077.1 - 2e-10 40.5 0.1 7.6e-10 38.6 0.0 1.9 1 1 1 2 2 2 1 LETM1-like protein S-AdoMet_synt_C PF02773.16 GAX17078.1 - 4.2e-65 217.9 0.1 9.3e-65 216.8 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GAX17078.1 - 1.5e-47 160.8 0.0 2.6e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GAX17078.1 - 3.3e-43 146.4 0.3 7e-43 145.3 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DXP_synthase_N PF13292.6 GAX17080.1 - 7.7e-106 353.3 0.0 2.4e-105 351.6 0.0 1.8 2 1 1 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 GAX17080.1 - 1e-41 142.5 0.1 1.9e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX17080.1 - 2.1e-23 82.5 0.0 6.3e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 GAX17080.1 - 1.3e-05 24.3 0.0 0.062 12.2 0.0 2.6 3 0 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 GAX17080.1 - 4e-05 23.5 0.1 9.6e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 GAX17080.1 - 0.00029 19.9 0.0 0.00054 19.0 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component GCV_T PF01571.21 GAX17081.1 - 1.5e-83 280.1 0.0 2.5e-83 279.4 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 GAX17081.1 - 2.4e-21 75.5 0.1 4.4e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 GAX17081.1 - 0.0047 17.1 0.0 0.015 15.5 0.0 1.8 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Ammonium_transp PF00909.21 GAX17082.1 - 5.8e-103 344.7 26.5 6.8e-103 344.4 26.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family His_Phos_1 PF00300.22 GAX17083.1 - 8.6e-30 103.9 0.1 1.1e-29 103.5 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADK PF00406.22 GAX17084.1 - 1.7e-42 145.1 0.0 2.1e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX17084.1 - 1.4e-31 109.7 0.0 1.9e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX17084.1 - 1.5e-10 41.7 0.0 2.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX17084.1 - 5.4e-05 23.4 0.0 0.00011 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAX17084.1 - 0.0063 16.2 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 GAX17084.1 - 0.044 14.0 0.0 0.46 10.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain WD40 PF00400.32 GAX17085.1 - 3.5e-23 81.4 19.0 2e-06 28.4 0.1 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17085.1 - 1.6e-17 63.6 2.8 6.1e-05 23.2 0.2 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX17085.1 - 9.2e-07 28.9 0.0 0.00045 20.1 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAX17085.1 - 3.7e-06 26.1 0.3 0.029 13.4 0.0 3.2 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAX17085.1 - 0.02 13.6 2.6 2.4 6.7 0.2 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 SR-25 PF10500.9 GAX17086.1 - 0.68 9.5 68.2 0.048 13.3 17.1 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein NST1 PF13945.6 GAX17086.1 - 8.2 6.5 46.6 1.6 8.8 13.0 3.3 3 0 0 3 3 3 0 Salt tolerance down-regulator PhyH PF05721.13 GAX17087.1 - 9.8e-06 26.0 0.0 2.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HMG_box_2 PF09011.10 GAX17087.1 - 0.017 15.7 0.6 0.36 11.5 0.6 2.8 2 0 0 2 2 2 0 HMG-box domain RPS31 PF17067.5 GAX17087.1 - 0.062 13.5 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S31e XAP5 PF04921.14 GAX17088.1 - 3.9e-75 252.9 12.0 6e-75 252.3 12.0 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF98 PF01947.16 GAX17088.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.0 2 0 0 2 2 2 0 p-hydroxybenzoic acid synthase U1snRNP70_N PF12220.8 GAX17088.1 - 0.51 11.0 16.9 0.53 11.0 7.9 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FAM60A PF15396.6 GAX17088.1 - 0.9 9.5 8.0 1.4 8.8 8.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A POPLD PF08170.12 GAX17088.1 - 6.3 7.2 6.3 24 5.4 0.5 2.6 2 0 0 2 2 2 0 POPLD (NUC188) domain TRAP-gamma PF07074.12 GAX17088.1 - 7.8 6.0 7.1 16 5.0 7.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Fe-ADH PF00465.19 GAX17089.1 - 5.4e-07 28.8 0.0 9.6e-06 24.6 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAX17089.1 - 0.00039 20.2 0.1 0.0025 17.6 0.0 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase ABC2_membrane PF01061.24 GAX17090.1 - 1.7e-33 115.8 22.0 2.5e-33 115.3 22.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX17090.1 - 6.1e-21 75.4 0.0 1.6e-20 74.1 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX17090.1 - 0.00028 20.1 16.6 0.00044 19.5 16.6 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAX17090.1 - 0.001 19.0 0.2 0.62 9.8 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAX17090.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAX17090.1 - 0.041 13.8 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 GAX17090.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 GAX17090.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein SMC_N PF02463.19 GAX17090.1 - 0.13 11.7 0.0 6 6.2 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Spindle_Spc25 PF08234.12 GAX17091.1 - 1.6e-18 66.7 0.4 1.6e-18 66.7 0.4 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4407 PF14362.6 GAX17091.1 - 0.0021 17.5 5.7 0.0029 17.0 5.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HOOK PF05622.12 GAX17091.1 - 0.0054 15.0 10.1 0.0067 14.6 10.1 1.1 1 0 0 1 1 1 1 HOOK protein DUF812 PF05667.11 GAX17091.1 - 0.013 14.5 7.9 0.017 14.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 GAX17091.1 - 0.024 14.2 4.0 0.034 13.7 4.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SpvB PF03534.13 GAX17091.1 - 0.054 12.7 0.9 0.075 12.2 0.9 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein Spc7 PF08317.11 GAX17091.1 - 0.066 12.1 17.9 0.13 11.1 17.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 GAX17091.1 - 0.18 11.9 18.0 0.96 9.5 17.7 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 GAX17091.1 - 0.25 10.4 5.2 0.38 9.8 5.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SKA2 PF16740.5 GAX17091.1 - 0.58 10.0 11.9 1.9 8.3 1.4 3.3 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 DHR10 PF18595.1 GAX17091.1 - 0.92 9.6 18.1 0.42 10.7 11.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain AAA_23 PF13476.6 GAX17091.1 - 1.2 9.6 9.4 2 8.9 9.4 1.4 1 0 0 1 1 1 0 AAA domain Med9 PF07544.13 GAX17091.1 - 1.2 9.3 7.5 0.91 9.7 3.8 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Spc24 PF08286.11 GAX17091.1 - 1.4 9.2 13.6 0.35 11.1 6.1 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 P4Ha_N PF08336.11 GAX17091.1 - 1.4 8.9 9.7 2.4 8.2 3.9 2.9 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FlaC_arch PF05377.11 GAX17091.1 - 1.4 9.3 6.8 4.5 7.8 2.5 3.3 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 GAX17091.1 - 1.9 7.8 8.2 3 7.1 8.2 1.3 1 0 0 1 1 1 0 FAM76 protein Synaptobrevin PF00957.21 GAX17091.1 - 2.2 8.1 4.8 3.3 7.6 4.2 1.6 1 1 0 1 1 1 0 Synaptobrevin ARGLU PF15346.6 GAX17091.1 - 2.6 7.9 20.5 6.8 6.6 20.5 1.6 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 DUF2730 PF10805.8 GAX17091.1 - 3.4 7.8 8.0 2.2 8.4 4.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) MCU PF04678.13 GAX17091.1 - 3.4 7.7 6.7 6.8 6.8 6.7 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF3450 PF11932.8 GAX17091.1 - 8 5.7 14.1 11 5.2 7.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NAD_binding_10 PF13460.6 GAX17092.1 - 5.5e-25 88.3 1.6 9.3e-25 87.6 1.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX17092.1 - 6.3e-07 28.7 0.1 9.4e-07 28.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAX17092.1 - 2.7e-05 23.8 0.1 4.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAX17092.1 - 5e-05 23.0 0.7 0.00012 21.7 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 GAX17092.1 - 0.016 14.3 0.1 0.035 13.2 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAX17092.1 - 0.028 13.6 0.5 0.066 12.3 0.5 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 GAX17092.1 - 0.081 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SPA PF08616.10 GAX17092.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 Stabilization of polarity axis LRR_8 PF13855.6 GAX17093.1 - 5.8e-22 77.2 30.2 1.6e-06 27.7 5.0 5.9 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAX17093.1 - 3.2e-13 49.6 27.3 3.1e-05 24.2 2.1 6.7 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX17093.1 - 1.8e-05 24.6 26.1 9.5 7.2 0.3 9.7 10 0 0 10 10 10 3 Leucine Rich Repeat Urease_gamma PF00547.18 GAX17093.1 - 2.2 8.6 3.7 26 5.2 0.1 3.1 2 1 1 3 3 3 0 Urease, gamma subunit Glyco_transf_64 PF09258.10 GAX17094.1 - 4.5e-38 130.9 0.0 6.8e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain SAP PF02037.27 GAX17095.1 - 2.1e-07 30.5 0.4 4.7e-07 29.4 0.4 1.7 1 0 0 1 1 1 1 SAP domain Nop53 PF07767.11 GAX17095.1 - 0.96 8.8 35.9 1.3 8.4 35.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GAX17095.1 - 1.6 6.9 31.5 1.9 6.6 31.5 1.0 1 0 0 1 1 1 0 Nop14-like family SRP-alpha_N PF04086.13 GAX17095.1 - 2.9 7.7 22.3 4 7.3 22.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 GAX17095.1 - 3.2 6.0 22.4 3.9 5.6 22.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SIR4_SID PF16991.5 GAX17095.1 - 4.3 7.4 9.6 0.68 10.0 4.9 1.8 1 1 1 2 2 2 0 Sir4 SID domain TAF6_C PF07571.13 GAX17096.1 - 7.1e-13 48.7 0.0 1.7e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TFIID-31kDa PF02291.15 GAX17096.1 - 0.002 18.2 0.1 0.0049 16.9 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 GAX17096.1 - 0.02 15.1 0.8 0.28 11.4 0.8 2.5 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Sec7_N PF12783.7 GAX17096.1 - 0.13 12.2 1.1 11 5.9 0.2 2.4 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PDZ PF00595.24 GAX17097.1 - 2.7e-08 34.0 0.0 6.8e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX17097.1 - 5.7e-06 26.1 0.1 1.1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX17097.1 - 0.0081 16.5 0.0 0.036 14.4 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Syntaxin-18_N PF10496.9 GAX17098.1 - 0.0043 17.3 3.3 0.0068 16.6 0.1 2.7 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DXP_reductoisom PF02670.16 GAX17098.1 - 0.063 14.0 0.4 1.7 9.4 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Tsc35 PF15079.6 GAX17098.1 - 3.8 7.0 6.4 3.8 7.0 0.5 2.8 2 1 1 3 3 3 0 Testis-specific protein 35 ubiquitin PF00240.23 GAX17099.1 - 3.4e-29 100.4 0.7 5.6e-29 99.7 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 GAX17099.1 - 3.3e-16 58.9 0.4 6e-16 58.0 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX17099.1 - 0.00044 20.6 0.0 0.0018 18.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain RBD PF02196.15 GAX17099.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Raf-like Ras-binding domain Ubiquitin_5 PF18037.1 GAX17099.1 - 0.038 14.4 0.1 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX17099.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Lipase_GDSL_2 PF13472.6 GAX17104.1 - 8.7e-26 91.4 0.0 1.5e-25 90.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX17104.1 - 6.9e-21 75.1 0.0 1e-20 74.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WD40 PF00400.32 GAX17105.1 - 1.9e-24 85.4 26.5 3.9e-06 27.5 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 GAX17105.1 - 1e-08 34.5 0.7 2.8e-08 33.2 0.7 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 GAX17105.1 - 3.9e-06 27.1 0.0 0.034 14.5 0.0 4.0 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX17105.1 - 0.023 13.7 0.1 1.6 7.6 0.0 3.0 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RL10P_insert PF17777.1 GAX17105.1 - 0.062 13.3 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P Skp1 PF01466.19 GAX17105.1 - 0.36 11.0 0.0 0.36 11.0 0.0 2.4 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Nup160 PF11715.8 GAX17105.1 - 0.37 9.4 3.1 0.93 8.1 0.2 2.7 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Methyltransf_12 PF08242.12 GAX17106.1 - 2.1e-09 38.0 0.0 5.3e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX17106.1 - 5.5e-09 36.1 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX17106.1 - 8.8e-08 32.8 0.0 2.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX17106.1 - 9.3e-08 32.0 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX17106.1 - 1.3e-07 32.1 0.0 4.3e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Bax1-I PF01027.20 GAX17107.1 - 8.5e-31 107.4 20.1 1.1e-30 107.0 20.1 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 YwiC PF14256.6 GAX17107.1 - 0.024 14.9 10.8 2.4 8.5 0.1 3.1 2 1 0 2 2 2 0 YwiC-like protein DUF2400 PF09674.10 GAX17107.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF4231 PF14015.6 GAX17107.1 - 6.6 7.3 8.3 15 6.2 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Clat_adaptor_s PF01217.20 GAX17108.1 - 2.1e-46 157.4 0.5 2.5e-46 157.1 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UCH PF00443.29 GAX17110.1 - 3.9e-66 223.2 0.0 1.3e-65 221.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX17110.1 - 4.1e-19 69.3 0.0 6.3e-12 45.7 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAX17110.1 - 6.8e-10 39.4 0.0 1.6e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 DUSP domain Peptidase_C98 PF15499.6 GAX17110.1 - 0.015 14.8 0.3 0.038 13.5 0.3 1.6 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase OTU PF02338.19 GAX17111.1 - 2.5e-14 53.9 0.0 5.3e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAX17111.1 - 0.015 14.7 0.0 0.11 11.9 0.0 2.0 1 1 1 2 2 2 0 Peptidase C65 Otubain F-box PF00646.33 GAX17112.1 - 4e-06 26.6 0.3 1.3e-05 24.9 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAX17112.1 - 0.00071 19.4 0.2 0.00071 19.4 0.2 2.6 2 0 0 2 2 2 1 F-box-like Motile_Sperm PF00635.26 GAX17112.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Metallophos PF00149.28 GAX17113.1 - 2.6e-38 132.6 0.1 3.4e-38 132.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAX17113.1 - 0.0031 17.9 0.1 0.0079 16.6 0.1 1.7 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 GAX17113.1 - 0.085 13.0 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Dymeclin PF09742.9 GAX17114.1 - 5.4e-64 216.7 4.2 8e-64 216.2 4.2 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Tim17 PF02466.19 GAX17115.1 - 2.3e-09 37.6 2.5 3.6e-09 37.0 2.4 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FUN14 PF04930.15 GAX17115.1 - 0.85 10.1 4.8 0.48 10.9 0.2 2.4 2 0 0 2 2 2 0 FUN14 family Lipase_GDSL PF00657.22 GAX17116.1 - 5e-06 26.6 0.0 6.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAX17116.1 - 5e-06 27.0 0.0 1.2e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family LBP_BPI_CETP_C PF02886.17 GAX17116.1 - 0.0015 18.1 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain GLEYA PF10528.9 GAX17116.1 - 0.033 14.6 0.1 0.078 13.4 0.0 1.6 2 0 0 2 2 2 0 GLEYA domain Ferlin_C PF16165.5 GAX17116.1 - 0.11 12.4 0.1 0.58 10.1 0.1 1.9 2 0 0 2 2 2 0 Ferlin C-terminus DUF4811 PF16069.5 GAX17117.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) NMD3 PF04981.13 GAX17118.1 - 7.9e-56 189.2 6.1 1.2e-55 188.7 6.1 1.3 1 0 0 1 1 1 1 NMD3 family zf-TFIIB PF13453.6 GAX17118.1 - 0.2 11.0 7.5 0.12 11.7 1.6 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger zinc_ribbon_15 PF17032.5 GAX17118.1 - 0.23 12.2 3.2 1.2 9.9 1.1 2.5 2 0 0 2 2 2 0 zinc-ribbon family Gln-synt_C PF00120.24 GAX17119.1 - 1.5e-20 73.5 0.0 8.9e-16 57.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GAX17119.1 - 2.4e-13 49.6 0.0 4.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Mur_ligase_M PF08245.12 GAX17119.1 - 0.04 13.9 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Mur ligase middle domain Radical_SAM PF04055.21 GAX17120.1 - 7.9e-05 23.1 0.0 0.0001 22.8 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily DUF4347 PF14252.6 GAX17121.1 - 0.027 14.3 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Lipase_3 PF01764.25 GAX17121.1 - 0.035 14.0 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) zf-MYND PF01753.18 GAX17122.1 - 4.6e-06 26.6 19.0 9.9e-06 25.5 19.0 1.6 1 0 0 1 1 1 1 MYND finger C2 PF00168.30 GAX17123.1 - 5e-20 71.7 0.0 2.2e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain Gelsolin PF00626.22 GAX17123.1 - 0.041 13.8 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 Gelsolin repeat CSRNP_N PF16019.5 GAX17124.1 - 0.0001 22.3 0.7 0.0001 22.3 0.7 1.6 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus EBP50_C PF09007.11 GAX17124.1 - 2.1 9.3 12.9 0.077 14.0 1.8 2.1 2 0 0 2 2 2 0 EBP50, C-terminal DUF2785 PF10978.8 GAX17125.1 - 0.092 12.5 0.4 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) ArfGap PF01412.18 GAX17126.1 - 2e-30 105.2 0.2 2.9e-30 104.7 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TackOD1 PF18551.1 GAX17126.1 - 0.049 13.3 0.7 0.071 12.8 0.2 1.5 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DUF1864 PF08933.11 GAX17126.1 - 0.069 11.9 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) ribosomal_L24 PF17136.4 GAX17127.1 - 1.9e-15 57.0 0.4 1.9e-15 57.0 0.4 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 GAX17127.1 - 0.018 15.0 3.2 0.027 14.4 0.3 2.4 2 0 0 2 2 2 0 KOW motif DUF1216 PF06746.11 GAX17128.1 - 0.0029 17.6 0.3 0.44 10.6 0.2 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1216) Plk4_PB2 PF18409.1 GAX17128.1 - 0.043 14.5 1.3 0.16 12.7 0.2 2.5 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 HeLo PF14479.6 GAX17128.1 - 0.044 13.6 1.1 0.18 11.6 0.1 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation MutS_III PF05192.18 GAX17128.1 - 0.058 13.6 5.6 0.041 14.1 0.4 2.5 1 1 0 2 2 2 0 MutS domain III CSD PF00313.22 GAX17129.1 - 8.7e-19 67.2 0.1 1.5e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 GAX17129.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain YjhX_toxin PF09857.9 GAX17129.1 - 0.025 14.5 0.2 0.35 10.8 0.0 2.5 3 0 0 3 3 3 0 Putative toxin of bacterial toxin-antitoxin pair Peptidase_C1 PF00112.23 GAX17130.1 - 6.6e-51 173.5 2.1 6.6e-51 173.5 2.1 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAX17130.1 - 9.6e-05 21.3 0.6 0.00079 18.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase C1-like family Inhibitor_I29 PF08246.12 GAX17130.1 - 0.091 13.2 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) L27_2 PF09045.10 GAX17130.1 - 0.79 9.7 2.7 31 4.6 0.0 3.0 3 0 0 3 3 3 0 L27_2 Pkinase PF00069.25 GAX17131.1 - 8.7e-54 182.6 0.1 2.6e-53 181.1 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17131.1 - 6.1e-25 88.0 0.1 8.7e-25 87.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX17131.1 - 0.00083 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX17131.1 - 0.0012 18.5 0.0 0.0059 16.2 0.0 2.0 1 1 0 2 2 2 1 Choline/ethanolamine kinase SelR PF01641.18 GAX17131.1 - 0.068 13.2 0.1 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 SelR domain ABC1 PF03109.16 GAX17131.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC1 family E1-E2_ATPase PF00122.20 GAX17132.1 - 9.1e-20 70.9 0.0 1.3e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 GAX17132.1 - 5e-05 22.9 0.0 8.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FliMN_C PF01052.20 GAX17132.1 - 0.067 13.2 0.3 0.8 9.7 0.0 2.4 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term Peptidase_S77 PF03420.13 GAX17132.1 - 0.094 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Prohead core protein serine protease SOUL PF04832.12 GAX17134.1 - 1.3e-35 123.1 0.0 3e-23 82.8 0.0 2.1 1 1 1 2 2 2 2 SOUL heme-binding protein SOUL PF04832.12 GAX17135.1 - 1.2e-41 142.6 0.0 2.1e-39 135.4 0.0 2.0 1 1 0 1 1 1 1 SOUL heme-binding protein Actin PF00022.19 GAX17136.1 - 1.2e-60 205.2 0.0 1.3e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAX17136.1 - 0.049 12.5 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Ribosomal_L30 PF00327.20 GAX17137.1 - 3.2e-07 30.1 0.1 6.1e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 GAX17137.1 - 0.14 12.4 7.8 0.048 13.9 4.7 1.8 1 1 0 1 1 1 0 Ribosomal L30 N-terminal domain YL1 PF05764.13 GAX17138.1 - 1.1 9.4 26.8 1.8 8.7 26.8 1.3 1 1 0 1 1 1 0 YL1 nuclear protein Aa_trans PF01490.18 GAX17139.1 - 3.1e-35 121.7 21.2 3.8e-35 121.4 21.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 GAX17140.1 - 9.9e-39 133.2 28.3 1.5e-38 132.6 28.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mob1_phocein PF03637.17 GAX17141.1 - 4.1e-47 160.3 0.0 4.8e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Ank_2 PF12796.7 GAX17142.1 - 2.9e-95 313.0 19.9 3.6e-15 56.3 0.0 8.8 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX17142.1 - 7.8e-80 262.3 5.0 2.2e-09 37.7 0.0 12.8 8 4 4 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 GAX17142.1 - 2.7e-66 217.3 14.5 5e-05 23.5 0.0 18.1 16 3 1 17 17 17 14 Ankyrin repeat Ank_5 PF13857.6 GAX17142.1 - 3.4e-66 218.4 19.7 2.1e-08 34.3 0.0 13.4 8 3 6 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17142.1 - 6.5e-60 192.0 6.3 0.00041 20.6 0.0 18.1 19 0 0 19 19 19 12 Ankyrin repeat Ricin_B_lectin PF00652.22 GAX17142.1 - 0.0037 17.5 0.7 0.026 14.8 0.2 2.4 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Arg_repressor PF01316.21 GAX17142.1 - 0.35 10.6 1.0 3.4 7.5 0.0 3.1 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain Sulfotransfer_2 PF03567.14 GAX17143.1 - 3.8e-25 89.3 0.0 5.4e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Pox_EPC_I2-L1 PF12575.8 GAX17143.1 - 0.11 12.8 0.9 18 5.7 0.1 2.4 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 RVT_2 PF07727.14 GAX17144.1 - 1.1e-41 143.1 1.5 1.4e-41 142.7 0.3 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX17144.1 - 7.2e-14 52.0 0.0 2.2e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GAX17144.1 - 1.5e-11 43.8 13.5 1.4e-06 28.1 2.0 2.6 2 0 0 2 2 2 2 Zinc knuckle gag_pre-integrs PF13976.6 GAX17144.1 - 6.1e-05 22.8 0.0 0.00018 21.3 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 GAX17144.1 - 0.00068 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 GAX17144.1 - 0.0013 18.6 13.8 0.003 17.5 3.3 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 GAX17144.1 - 0.0033 17.1 4.6 0.53 10.1 0.3 3.2 3 0 0 3 3 3 2 Zinc knuckle Gag_p15 PF08723.10 GAX17144.1 - 0.058 13.6 0.7 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Gag protein p15 zf-CCHC_6 PF15288.6 GAX17144.1 - 0.27 11.1 11.9 3.6 7.5 4.5 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 GAX17144.1 - 10 6.0 12.1 0.28 10.9 1.5 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Lactamase_B PF00753.27 GAX17145.1 - 6.9e-07 29.5 1.1 5.3e-06 26.6 1.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily CBM_6 PF03422.15 GAX17146.1 - 5.4e-41 139.8 10.8 1.9e-23 83.1 0.2 3.3 3 0 0 3 3 3 2 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX17146.1 - 7.6e-29 101.0 11.6 1.2e-28 100.4 11.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX17146.1 - 1.1e-11 44.8 7.1 5.3e-05 23.3 0.1 3.7 4 0 0 4 4 4 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX17146.1 - 0.0013 19.0 6.1 1.1 9.5 0.1 3.2 2 1 0 2 2 2 2 Carbohydrate binding module (family 35) CopC PF04234.12 GAX17146.1 - 0.015 16.4 0.1 10 7.2 0.0 2.7 2 0 0 2 2 2 0 CopC domain DUF5011 PF16403.5 GAX17146.1 - 0.019 15.1 0.8 0.55 10.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Endotoxin_C PF03944.14 GAX17146.1 - 0.12 12.7 0.7 0.32 11.3 0.4 1.8 2 0 0 2 2 2 0 delta endotoxin DUF4045 PF13254.6 GAX17147.1 - 0.092 12.4 4.2 0.1 12.2 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4703 PF15775.5 GAX17147.1 - 8.8 6.1 9.7 1.4 8.7 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4703) TerD PF02342.18 GAX17149.1 - 4.8e-16 58.8 0.0 3.5e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 TerD domain C2 PF00168.30 GAX17149.1 - 1.1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain TerD PF02342.18 GAX17153.1 - 3.7e-07 29.8 0.0 0.0022 17.5 0.0 3.0 2 2 0 2 2 2 2 TerD domain C2 PF00168.30 GAX17153.1 - 1.1e-06 28.8 0.0 2.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF3053 PF11254.8 GAX17153.1 - 0.19 11.3 0.0 0.53 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) TerD PF02342.18 GAX17154.1 - 0.0086 15.6 0.0 1.5 8.3 0.0 2.9 2 1 0 2 2 2 2 TerD domain TerD PF02342.18 GAX17155.1 - 9.6e-15 54.5 0.0 1.3e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 TerD domain C2 PF00168.30 GAX17155.1 - 1.7e-10 41.1 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain KAAG1 PF15354.6 GAX17155.1 - 1.5 9.4 6.5 16 6.1 0.1 3.0 2 1 1 3 3 3 0 Kidney-associated antigen 1 TerD PF02342.18 GAX17156.1 - 1.5e-14 53.9 0.0 1.9e-08 34.0 0.0 2.6 2 1 0 2 2 2 2 TerD domain C2 PF00168.30 GAX17156.1 - 1.8e-09 37.8 0.0 4.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Glyco_transf_8 PF01501.20 GAX17157.1 - 4.1e-07 29.8 0.4 0.00026 20.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 DUF5050 PF16472.5 GAX17157.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) Mannosyl_trans3 PF11051.8 GAX17157.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Sulfotransfer_4 PF17784.1 GAX17159.1 - 9.9e-07 28.8 0.8 7.4e-06 25.9 0.8 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX17159.1 - 0.00017 22.1 0.1 0.087 13.2 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family S10_plectin PF03501.15 GAX17160.1 - 1.5e-37 127.5 0.1 1.7e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF4687 PF15747.5 GAX17160.1 - 0.019 15.4 0.2 0.029 14.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) Glyco_transf_8 PF01501.20 GAX17161.1 - 0.0006 19.4 0.5 0.79 9.2 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAX17161.1 - 0.013 14.8 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 GAX17162.1 - 4.6e-05 23.1 1.1 0.029 13.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAX17162.1 - 0.0044 16.4 0.1 0.0075 15.7 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative ThiF PF00899.21 GAX17163.1 - 1.3e-89 299.7 0.0 1.7e-68 230.6 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAX17163.1 - 9.9e-78 261.5 0.2 2.7e-77 260.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GAX17163.1 - 5.9e-29 100.6 0.3 1.4e-28 99.4 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GAX17163.1 - 7.8e-19 67.6 0.7 1.8e-18 66.5 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 GAX17163.1 - 2e-18 66.3 0.2 3.9e-18 65.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain CTD_bind PF04818.13 GAX17164.1 - 2.8e-14 53.7 0.0 1.4e-13 51.4 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase II-binding domain. BAG PF02179.16 GAX17164.1 - 0.015 15.7 3.4 0.044 14.2 2.9 2.2 1 1 0 1 1 1 0 BAG domain MSP1a PF11670.8 GAX17164.1 - 0.28 10.4 1.6 0.59 9.4 1.6 1.5 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) TYW3 PF02676.14 GAX17165.1 - 9.4e-39 133.0 0.0 1.7e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.16 GAX17165.1 - 3.3e-21 76.0 0.0 5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein T4BSS_DotI_IcmL PF11393.8 GAX17165.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Type-IV b secretion system, inner-membrane complex component CENP-N PF05238.13 GAX17166.1 - 1.8e-06 27.5 0.7 3e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Kinetochore protein CHL4 like HATPase_c PF02518.26 GAX17168.1 - 2e-22 79.8 0.0 4.5e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX17168.1 - 9.1e-20 70.9 0.6 1.7e-19 70.0 0.6 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX17168.1 - 7.3e-15 54.8 0.2 2.2e-14 53.2 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX17168.1 - 0.00075 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC1 PF03109.16 GAX17169.1 - 1.1e-30 106.2 0.0 2.5e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX17169.1 - 1.9e-06 28.0 0.0 5.6e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX17169.1 - 3.8e-05 23.2 0.0 0.0013 18.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Glyco_transf_10 PF00852.19 GAX17170.1 - 1.4e-28 99.8 0.0 2.8e-27 95.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Ank_2 PF12796.7 GAX17171.1 - 1.5e-13 51.1 2.7 2.1e-07 31.4 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX17171.1 - 7e-12 45.6 0.8 1.1e-06 29.0 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17171.1 - 6.1e-05 23.1 0.0 0.0004 20.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GAX17171.1 - 0.00012 22.3 0.1 0.00072 19.8 0.1 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX17171.1 - 0.0015 18.9 0.0 0.037 14.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Shigella_OspC PF06128.11 GAX17171.1 - 0.049 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Shigella flexneri OspC protein DUF1700 PF08006.11 GAX17172.1 - 2.4 7.7 10.0 0.62 9.6 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) CNH PF00780.22 GAX17173.1 - 0.01 15.5 0.2 3.3 7.3 0.1 2.7 3 0 0 3 3 3 0 CNH domain ANAPC4_WD40 PF12894.7 GAX17173.1 - 0.11 12.9 0.0 0.55 10.6 0.0 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX17173.1 - 0.13 13.2 3.3 2 9.4 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat WD40_like PF17005.5 GAX17173.1 - 0.16 11.3 0.1 3.6 6.8 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain Pkinase PF00069.25 GAX17175.1 - 6.5e-07 29.0 0.1 2.2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17175.1 - 5.4e-05 22.6 0.1 0.0004 19.7 0.1 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Thymidylate_kin PF02223.17 GAX17176.1 - 7.8e-45 152.8 0.0 9.3e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 GAX17176.1 - 0.016 15.8 0.0 0.035 14.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX17176.1 - 0.046 14.0 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GAX17176.1 - 0.053 13.3 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 GAX17176.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX17176.1 - 0.095 13.1 0.1 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 GAX17176.1 - 0.14 12.6 0.0 1.8 9.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.12 GAX17177.1 - 5.2e-92 307.4 0.0 6.5e-92 307.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAX17177.1 - 8.4e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAX17177.1 - 2.6e-07 30.4 0.0 5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX17177.1 - 4e-07 30.3 0.0 1.2e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAX17177.1 - 0.00066 19.7 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAX17177.1 - 0.06 12.5 2.7 2.5 7.2 0.0 2.9 1 1 1 3 3 3 0 G-protein alpha subunit SRPRB PF09439.10 GAX17177.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 GAX17177.1 - 0.2 11.4 0.5 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.16 GAX17178.1 - 2.8e-25 89.0 39.6 6.3e-19 68.1 24.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX17178.1 - 1.1e-07 31.1 7.4 1.1e-07 31.1 7.4 3.4 2 2 1 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 GAX17178.1 - 0.00076 17.8 1.2 0.00076 17.8 1.2 1.6 2 0 0 2 2 2 1 BT1 family OATP PF03137.20 GAX17178.1 - 0.0039 15.6 2.3 0.073 11.3 0.2 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Ldr_toxin PF13940.6 GAX17178.1 - 0.058 13.5 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system YL1 PF05764.13 GAX17179.1 - 0.0014 18.8 20.2 0.0014 18.8 20.2 7.4 3 2 3 6 6 6 1 YL1 nuclear protein MRC1 PF09444.10 GAX17179.1 - 0.011 16.3 27.6 0.011 16.3 27.6 9.1 5 2 4 9 9 9 0 MRC1-like domain Hexapep PF00132.24 GAX17180.1 - 9.4e-12 44.2 12.6 3.6e-05 23.3 0.0 4.3 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAX17180.1 - 1.3e-05 24.8 7.2 0.001 18.8 0.1 3.9 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 GAX17181.1 - 0.1 12.3 0.5 0.21 11.3 0.5 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FPP PF05911.11 GAX17181.1 - 1.8 6.7 51.7 0.0042 15.4 26.7 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil MatE PF01554.18 GAX17182.1 - 3.7e-22 78.7 29.8 1.1e-20 73.9 8.2 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAX17182.1 - 4.8e-06 26.7 7.8 4.8e-06 26.7 7.8 3.2 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF3341 PF11821.8 GAX17182.1 - 2.3 7.8 6.0 1.1 8.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) Ribosomal_L3 PF00297.22 GAX17183.1 - 1.6e-143 478.2 9.6 1.8e-143 478.0 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NCBP3 PF10309.9 GAX17184.1 - 8.2e-12 44.8 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 GAX17184.1 - 1.9e-06 27.8 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain HHV-5_US34A PF17087.5 GAX17184.1 - 0.092 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus US34A protein family Methyltransf_FA PF12248.8 GAX17184.1 - 0.12 12.7 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase Histone_HNS PF00816.21 GAX17184.1 - 2.6 8.9 8.5 0.85 10.5 0.1 3.4 3 1 1 4 4 4 0 H-NS histone family HhH-GPD PF00730.25 GAX17185.1 - 0.00034 21.0 0.0 0.00072 20.0 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein zf-MYND PF01753.18 GAX17186.1 - 3e-08 33.6 18.0 5.7e-08 32.7 18.0 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 GAX17186.1 - 1.1 9.4 9.7 2.2 8.4 9.7 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ank_4 PF13637.6 GAX17187.1 - 1.6e-08 34.9 0.1 0.0004 20.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX17187.1 - 4.7e-08 33.5 0.0 9.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX17187.1 - 2.3e-06 27.5 0.2 1.7e-05 24.9 0.0 2.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 GAX17187.1 - 0.00013 22.3 0.0 0.00055 20.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GAX17187.1 - 0.00018 21.8 0.0 0.00041 20.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 GAX17187.1 - 0.042 14.7 0.0 0.086 13.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 GAX17188.1 - 3.9e-07 30.6 0.0 6.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX17188.1 - 7.1e-06 26.0 0.0 0.0019 18.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 GAX17188.1 - 0.0059 17.2 0.0 0.048 14.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 GAX17188.1 - 0.1 13.5 0.0 0.2 12.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 GAX17189.1 - 4.4e-11 43.2 0.4 4e-09 36.9 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX17189.1 - 5.7e-11 42.7 0.7 2.1e-06 28.1 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17189.1 - 2.1e-08 33.8 1.1 1.4e-05 25.1 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 GAX17189.1 - 3.9e-07 30.2 0.2 2.7e-06 27.5 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX17189.1 - 6.7e-07 29.5 2.3 3.6e-05 24.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 GAX17189.1 - 0.053 14.4 0.0 0.14 13.1 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF155 PF02582.14 GAX17190.1 - 6.3e-23 81.8 0.1 1e-22 81.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Androgen_recep PF02166.16 GAX17190.1 - 0.16 10.8 2.7 0.23 10.3 2.7 1.1 1 0 0 1 1 1 0 Androgen receptor SNARE PF05739.19 GAX17191.1 - 1.7e-15 56.7 0.1 4.2e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GAX17191.1 - 9.1e-05 22.2 9.2 0.0014 18.3 0.1 2.5 3 0 0 3 3 3 2 Syntaxin Syntaxin_2 PF14523.6 GAX17191.1 - 0.016 15.5 3.4 0.043 14.2 0.5 2.3 2 1 0 2 2 2 0 Syntaxin-like protein DLP_helical PF18709.1 GAX17191.1 - 0.019 14.2 3.2 0.016 14.4 1.3 1.8 1 1 0 1 1 1 0 Dynamin-like helical domain Mit_KHE1 PF10173.9 GAX17191.1 - 0.046 13.8 0.5 0.58 10.2 0.1 2.5 2 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related APP_E2 PF12925.7 GAX17191.1 - 0.048 13.4 1.1 0.064 13.0 0.1 1.7 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein AdoHcyase PF05221.17 GAX17191.1 - 0.052 12.7 1.1 0.075 12.2 0.3 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase zf-C4H2 PF10146.9 GAX17191.1 - 0.16 12.2 1.8 0.6 10.4 1.8 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1043 PF06295.12 GAX17191.1 - 0.21 11.6 2.5 1 9.4 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Synaptobrevin PF00957.21 GAX17191.1 - 1 9.2 5.3 0.74 9.6 0.7 2.4 2 0 0 2 2 2 0 Synaptobrevin DUF16 PF01519.16 GAX17191.1 - 1.3 9.6 4.9 1.1 9.7 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Semialdhyde_dh PF01118.24 GAX17192.1 - 9e-09 35.8 0.6 4.3e-08 33.6 0.1 2.3 3 1 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain UCR_hinge PF02320.16 GAX17193.1 - 0.046 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Hydrolase_like PF13242.6 GAX17194.1 - 1.8e-16 60.0 0.0 2e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 GAX17194.1 - 6.9e-14 51.8 0.0 2.5e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX17194.1 - 4.7e-12 46.6 0.0 2.5e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX17194.1 - 4.4e-10 39.9 0.0 1.7e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase STI1 PF17830.1 GAX17195.1 - 0.0031 17.4 5.1 0.76 9.8 0.1 3.4 3 0 0 3 3 3 2 STI1 domain Epimerase PF01370.21 GAX17196.1 - 4.6e-18 65.6 0.0 3.6e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX17196.1 - 2.4e-10 40.4 0.0 0.00019 21.0 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAX17196.1 - 5e-10 39.6 0.0 1.3e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX17196.1 - 0.023 14.3 0.0 0.057 13.0 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family Cupin_4 PF08007.12 GAX17197.1 - 5.1e-17 62.3 0.0 9.2e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 GAX17197.1 - 0.0003 20.6 0.0 0.0013 18.5 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain Pkinase PF00069.25 GAX17198.1 - 7.4e-59 199.3 1.5 3.1e-57 194.0 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17198.1 - 9.8e-27 93.9 0.3 7.9e-26 90.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 GAX17198.1 - 7.8e-25 84.5 11.0 1.7e-07 30.3 0.4 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAX17198.1 - 6.7e-23 80.9 9.8 4.9e-10 39.7 3.2 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 GAX17198.1 - 5.8e-22 77.3 9.8 3.7e-10 39.5 0.8 4.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GAX17198.1 - 3.9e-19 66.9 9.2 1.3e-06 27.9 0.3 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAX17198.1 - 1.8e-14 52.5 10.5 0.00019 20.8 0.4 4.6 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 GAX17198.1 - 2.2e-08 34.4 0.6 0.0044 17.3 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAX17198.1 - 7.3e-07 29.1 1.6 0.013 15.4 0.1 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 GAX17198.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX17198.1 - 5.7e-05 22.1 0.2 0.00015 20.7 0.1 1.7 1 1 1 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 GAX17198.1 - 0.0004 20.1 0.1 1.3 8.6 0.0 2.9 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GAX17198.1 - 0.001 18.7 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family EF-hand_11 PF08976.11 GAX17198.1 - 0.0034 18.2 1.6 0.81 10.6 0.1 2.8 2 1 1 3 3 2 1 EF-hand domain Kinase-like PF14531.6 GAX17198.1 - 0.0043 16.4 0.3 0.042 13.2 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAX17198.1 - 0.0083 15.1 0.3 0.017 14.1 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAX17198.1 - 0.021 14.7 0.0 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3037 PF11236.8 GAX17198.1 - 0.059 13.8 0.2 3.1 8.2 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3037) Caleosin PF05042.13 GAX17198.1 - 0.062 13.2 1.1 0.79 9.6 0.2 2.7 1 1 2 3 3 3 0 Caleosin related protein DUF2666 PF10869.8 GAX17198.1 - 0.11 12.8 0.2 1.5 9.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Nod1 PF17114.5 GAX17198.1 - 0.15 12.2 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Pkinase PF00069.25 GAX17199.1 - 2.7e-59 200.7 4.9 4.1e-59 200.1 1.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17199.1 - 8.3e-35 120.3 0.9 1.2e-34 119.8 0.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX17199.1 - 1.5e-17 63.8 3.0 3.2e-08 33.9 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX17199.1 - 1.3e-15 55.9 2.8 9.6e-05 22.0 0.3 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 GAX17199.1 - 4.6e-13 47.7 1.1 0.017 14.6 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAX17199.1 - 1.1e-07 31.6 2.6 0.044 13.6 0.0 4.4 1 1 3 4 4 4 3 EF-hand domain pair Pkinase_fungal PF17667.1 GAX17199.1 - 1.1e-06 27.7 0.3 1.6e-06 27.1 0.3 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX17199.1 - 5.7e-05 22.6 0.3 0.00016 21.1 0.1 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAX17199.1 - 0.0089 15.6 0.4 0.018 14.7 0.4 1.5 1 0 0 1 1 1 1 RIO1 family HrpB1_HrpK PF09613.10 GAX17199.1 - 0.011 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) FliG_N PF14842.6 GAX17199.1 - 0.086 13.4 0.6 8.3 7.0 0.2 3.3 3 0 0 3 3 3 0 FliG N-terminal domain N_formyltrans_C PF18216.1 GAX17199.1 - 0.11 12.2 0.2 0.34 10.6 0.2 1.9 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain EF-hand_5 PF13202.6 GAX17199.1 - 4.2 7.0 6.2 75 3.1 0.0 4.2 4 0 0 4 4 4 0 EF hand His_Phos_2 PF00328.22 GAX17200.1 - 1.1e-71 242.3 0.0 1.9e-71 241.5 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 GAX17200.1 - 3.8e-38 129.5 0.1 8.6e-38 128.4 0.1 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GAX17200.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF2254 PF10011.9 GAX17201.1 - 2e-64 217.7 1.1 3.7e-64 216.9 1.1 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2254) CobN-Mg_chel PF02514.16 GAX17202.1 - 0 1120.5 0.0 0 1120.2 0.0 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 GAX17202.1 - 1e-52 178.5 1.3 2.6e-52 177.2 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) Steroid_dh PF02544.16 GAX17203.1 - 3e-22 79.2 1.3 4.4e-22 78.7 1.3 1.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PelG PF16933.5 GAX17203.1 - 0.048 12.5 0.3 0.08 11.8 0.3 1.3 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) COQ9 PF08511.11 GAX17204.1 - 0.021 14.6 0.1 0.05 13.4 0.1 1.7 1 0 0 1 1 1 0 COQ9 HA PF03457.14 GAX17205.1 - 1.4e-56 188.7 19.7 6.3e-18 64.9 0.2 4.4 4 0 0 4 4 4 4 Helicase associated domain Antirestrict PF03230.13 GAX17205.1 - 0.12 12.5 4.3 3.8 7.6 0.1 3.9 4 0 0 4 4 4 0 Antirestriction protein zf-MYND PF01753.18 GAX17206.1 - 1.1e-06 28.6 14.3 2.1e-06 27.7 14.3 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 GAX17206.1 - 3.3 7.6 10.0 23 5.0 10.1 2.3 1 1 0 1 1 1 0 HIT zinc finger TPR_1 PF00515.28 GAX17207.1 - 1.2e-09 37.6 0.4 0.17 11.7 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17207.1 - 3.7e-09 36.0 1.3 0.61 10.3 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17207.1 - 6.1e-07 29.2 0.5 7 7.1 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX17207.1 - 2.5e-06 27.7 4.8 0.02 15.2 0.9 4.0 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX17207.1 - 2.8e-06 27.7 4.5 0.6 10.7 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX17207.1 - 3.3e-05 24.5 2.7 0.42 11.3 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17207.1 - 0.0011 18.8 0.5 1.2 9.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX17207.1 - 0.0017 18.6 5.4 9.3 6.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX17207.1 - 0.0025 18.3 5.6 2.1 9.2 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17207.1 - 0.02 15.6 5.8 4 8.5 0.0 4.6 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17207.1 - 0.024 14.5 3.3 6 6.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX17207.1 - 0.031 13.9 0.0 8.7 6.1 0.0 3.0 2 2 0 2 2 2 0 TPR repeat Wzy_C_2 PF11846.8 GAX17207.1 - 0.048 13.6 0.3 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 GAX17207.1 - 0.068 13.4 0.0 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DnaJ PF00226.31 GAX17208.1 - 7.5e-23 80.4 0.8 7.5e-23 80.4 0.8 2.0 2 0 0 2 2 2 1 DnaJ domain NYN_YacP PF05991.11 GAX17209.1 - 0.00096 19.1 0.0 0.0017 18.3 0.0 1.4 1 1 0 1 1 1 1 YacP-like NYN domain DUF1349 PF07081.11 GAX17210.1 - 3e-38 131.3 0.1 5.8e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) RmlD_sub_bind PF04321.17 GAX17210.1 - 1.6e-25 89.8 0.3 2.1e-24 86.1 0.3 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 GAX17210.1 - 4.2e-21 75.5 0.0 5.7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX17210.1 - 6.8e-15 55.3 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX17210.1 - 2.4e-07 30.2 0.0 3.7e-06 26.3 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAX17210.1 - 0.00038 19.7 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 GAX17210.1 - 0.0097 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 GAX17210.1 - 0.011 14.7 0.0 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GH43_C2 PF17851.1 GAX17210.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain ANAPC4_WD40 PF12894.7 GAX17211.1 - 0.0012 19.1 0.1 8.1 6.8 0.0 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4945 PF16303.5 GAX17211.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) WD40 PF00400.32 GAX17211.1 - 2.4 9.2 5.2 1.5e+02 3.5 0.1 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat AA_kinase PF00696.28 GAX17212.1 - 8e-36 123.8 0.0 1.8e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 GAX17212.1 - 7.9e-11 41.1 1.4 4.2e-09 35.4 0.9 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family WD40 PF00400.32 GAX17213.1 - 1.2e-07 32.3 6.6 0.036 15.0 0.0 6.2 8 0 0 8 8 8 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 GAX17213.1 - 2.5e-07 30.2 7.9 2.5e-07 30.2 7.9 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 GAX17213.1 - 0.074 13.3 8.3 0.19 12.0 8.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family QVR PF17064.5 GAX17213.1 - 0.2 11.9 4.5 0.47 10.7 4.5 1.5 1 0 0 1 1 1 0 Sleepless protein DZR PF12773.7 GAX17213.1 - 4.7 7.3 10.5 67 3.6 10.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon SBF PF01758.16 GAX17214.1 - 3e-29 102.1 14.7 5.1e-29 101.3 14.7 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 GAX17214.1 - 2.8e-13 49.9 21.2 3.6e-13 49.5 21.2 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) VAR1 PF05316.12 GAX17214.1 - 0.24 10.4 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) SRP54 PF00448.22 GAX17215.1 - 4.7e-76 254.8 0.1 8.3e-76 254.0 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAX17215.1 - 4.5e-26 91.3 1.1 4.5e-26 91.3 1.1 3.6 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 GAX17215.1 - 5.1e-13 49.1 2.7 1.5e-12 47.5 2.7 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 GAX17215.1 - 2.4e-07 30.3 1.1 5.9e-07 29.0 0.0 2.0 2 1 1 3 3 3 1 Zeta toxin AAA_16 PF13191.6 GAX17215.1 - 9.2e-07 29.4 0.0 4.3e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 GAX17215.1 - 1.1e-05 25.1 0.3 0.00017 21.2 0.3 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAX17215.1 - 2.4e-05 24.2 0.1 0.0001 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX17215.1 - 0.00031 20.9 0.1 0.0032 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 GAX17215.1 - 0.0007 19.6 0.0 0.003 17.6 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Med8 PF10232.9 GAX17215.1 - 0.0018 17.9 0.0 0.3 10.6 0.0 2.6 2 1 1 3 3 3 1 Mediator of RNA polymerase II transcription complex subunit 8 AAA_22 PF13401.6 GAX17215.1 - 0.0043 17.3 0.3 0.036 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 GAX17215.1 - 0.0067 16.3 0.7 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_19 PF13245.6 GAX17215.1 - 0.0073 16.6 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 GAX17215.1 - 0.0076 16.3 0.7 0.039 14.0 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 GAX17215.1 - 0.011 14.7 0.0 0.011 14.7 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 GAX17215.1 - 0.013 15.5 0.2 0.033 14.2 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 GAX17215.1 - 0.015 15.7 0.3 0.17 12.3 0.0 3.0 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) CLP1_P PF16575.5 GAX17215.1 - 0.017 14.9 0.1 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 GAX17215.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 GAX17215.1 - 0.02 14.4 0.2 0.075 12.5 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX17215.1 - 0.031 13.8 2.7 0.039 13.5 0.2 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.14 GAX17215.1 - 0.038 13.9 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Cys_Met_Meta_PP PF01053.20 GAX17215.1 - 0.04 12.4 0.0 0.063 11.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ATPase PF06745.13 GAX17215.1 - 0.05 12.9 0.9 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 KaiC Thymidylate_kin PF02223.17 GAX17215.1 - 0.064 12.9 0.1 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_17 PF13207.6 GAX17215.1 - 2.1 8.7 7.1 0.32 11.4 0.1 3.1 3 1 0 3 3 2 0 AAA domain Cwf_Cwc_15 PF04889.12 GAX17216.1 - 6e-36 124.4 18.4 7.3e-36 124.2 18.4 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GAX17216.1 - 0.00027 19.3 16.6 0.00033 19.1 16.6 1.0 1 0 0 1 1 1 1 Nop14-like family MFAP1 PF06991.11 GAX17216.1 - 0.0025 17.7 17.0 0.004 17.0 17.0 1.3 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing DNA_pol_phi PF04931.13 GAX17216.1 - 1.7 6.7 23.4 2 6.4 23.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 GAX17216.1 - 1.8 8.3 14.0 2.4 7.9 12.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) Nas2_N PF18265.1 GAX17217.1 - 1.1e-19 70.1 0.1 2.5e-19 69.0 0.1 1.7 1 1 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 GAX17217.1 - 6.4e-06 25.9 0.2 2.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX17217.1 - 0.00025 21.3 0.0 0.00054 20.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 GAX17217.1 - 0.002 18.5 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain TLE_N PF03920.15 GAX17217.1 - 0.075 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain HA2 PF04408.23 GAX17219.1 - 4.8e-20 71.9 0.0 4.8e-20 71.9 0.0 4.1 5 1 0 5 5 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX17219.1 - 7.7e-14 51.8 0.0 2.8e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX17219.1 - 3.9e-13 49.7 0.0 8.6e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX17219.1 - 4.7e-07 29.7 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX17219.1 - 0.00043 20.6 0.1 0.0016 18.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX17219.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAX17219.1 - 0.019 14.0 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 GAX17219.1 - 0.029 14.1 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 GAX17219.1 - 0.033 14.7 0.2 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 GAX17219.1 - 0.056 13.9 0.1 0.056 13.9 0.1 3.8 3 2 0 3 3 2 0 AAA domain ATPase PF06745.13 GAX17219.1 - 0.09 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 KaiC SRP54 PF00448.22 GAX17219.1 - 0.1 12.2 0.2 0.25 10.9 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 GAX17219.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAX17219.1 - 0.38 10.6 1.8 2 8.3 0.1 2.7 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 GAX17219.1 - 1.5 8.3 3.9 0.31 10.5 0.1 1.8 2 0 0 2 2 1 0 P-loop containing dynein motor region ABC1 PF03109.16 GAX17221.1 - 1.4e-33 115.6 0.0 4.5e-33 113.9 0.0 1.9 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX17221.1 - 0.0082 16.1 0.1 0.041 13.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX17221.1 - 0.02 14.3 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain GerD PF17898.1 GAX17222.1 - 0.00065 19.6 0.8 0.25 11.3 0.1 2.5 2 0 0 2 2 2 2 Spore germination GerD central core domain IL32 PF15225.6 GAX17222.1 - 2.8 8.4 6.0 6.9 7.1 0.3 3.3 2 1 1 3 3 3 0 Interleukin 32 Bromodomain PF00439.25 GAX17223.1 - 3.7e-93 305.7 5.6 1.4e-15 57.1 0.1 6.6 6 0 0 6 6 6 6 Bromodomain Fucose_iso_N2 PF07882.12 GAX17223.1 - 0.042 13.4 0.1 8.1 6.0 0.0 3.2 3 0 0 3 3 3 0 L-fucose isomerase, second N-terminal domain DUF285 PF03382.14 GAX17224.1 - 2.4e-82 272.6 38.4 6.2e-31 106.7 6.1 3.5 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 DrrA_P4M PF14860.6 GAX17224.1 - 0.027 14.3 3.0 14 5.6 0.1 4.1 3 2 1 4 4 4 0 DrrA phosphatidylinositol 4-phosphate binding domain Bromodomain PF00439.25 GAX17224.1 - 0.11 12.5 0.6 13 5.9 0.0 3.9 5 0 0 5 5 5 0 Bromodomain ABC1 PF03109.16 GAX17225.1 - 2.3e-23 82.6 0.0 4.9e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX17225.1 - 4.6e-08 33.3 1.1 4.2e-06 26.9 0.4 3.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX17225.1 - 9e-06 25.2 0.0 3.4e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GAX17226.1 - 6.9e-33 112.2 22.0 1.6e-05 25.6 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17226.1 - 7.6e-09 35.8 1.4 1.4 9.2 0.0 5.2 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nop53 PF07767.11 GAX17227.1 - 8.9e-32 111.0 35.8 2.1e-31 109.7 35.8 1.7 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4279 PF14106.6 GAX17227.1 - 0.0074 16.5 0.5 0.016 15.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4279) Rubis-subs-bind PF09273.11 GAX17228.1 - 4.5e-25 88.8 0.1 8.1e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 GAX17228.1 - 8.5e-15 55.5 0.0 1.8e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 SET domain Peptidase_S8 PF00082.22 GAX17229.1 - 5e-37 127.8 2.9 4.2e-25 88.6 0.2 2.4 3 0 0 3 3 3 2 Subtilase family PA PF02225.22 GAX17229.1 - 1.9e-08 34.2 0.0 4.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 PA domain SURF6 PF04935.12 GAX17230.1 - 1.6e-23 83.6 45.3 1.6e-23 83.6 45.3 2.2 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 GAX17230.1 - 6.1e-13 49.2 0.1 6.1e-13 49.2 0.1 5.1 3 2 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 DUF2486 PF10667.9 GAX17230.1 - 8.4 6.5 19.6 1.2 9.2 15.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2486) SSF PF00474.17 GAX17231.1 - 1e-21 77.3 18.2 6.7e-19 68.0 11.6 2.2 2 0 0 2 2 2 2 Sodium:solute symporter family SSF PF00474.17 GAX17232.1 - 4.2e-19 68.7 16.5 3.4e-17 62.4 9.7 2.2 2 0 0 2 2 2 2 Sodium:solute symporter family PA PF02225.22 GAX17233.1 - 0.0084 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 PA domain Sulfatase PF00884.23 GAX17233.1 - 0.062 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Sulfatase PCI PF01399.27 GAX17234.1 - 2.5e-07 31.2 0.0 5.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 GAX17234.1 - 0.13 12.6 0.1 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 GAX17235.1 - 6.9e-13 48.9 10.6 6.9e-05 23.5 0.4 5.8 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17235.1 - 1e-07 32.1 0.0 0.00011 22.4 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX17235.1 - 5.2e-05 23.2 0.0 0.038 13.9 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_C PF00034.21 GAX17236.1 - 2.5e-13 51.0 0.1 3.7e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GAX17236.1 - 1.1e-05 25.6 2.3 3.8e-05 23.9 2.3 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAX17236.1 - 0.0039 16.9 0.7 0.044 13.5 0.3 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 GAX17236.1 - 0.055 13.8 1.0 7.5 6.9 0.4 2.1 2 0 0 2 2 2 0 Cytochrome P460 PUB PF09409.10 GAX17237.1 - 1.7e-19 69.5 0.9 4.5e-19 68.2 0.1 2.0 2 0 0 2 2 2 1 PUB domain Thioredoxin PF00085.20 GAX17237.1 - 1.1e-11 44.6 0.0 2.9e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin zf-C2H2 PF00096.26 GAX17237.1 - 0.004 17.5 0.1 0.009 16.4 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type Thioredoxin_2 PF13098.6 GAX17237.1 - 0.021 15.2 1.9 0.29 11.6 0.0 3.1 2 2 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX17237.1 - 0.028 14.8 0.0 0.42 11.0 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX17237.1 - 0.048 13.4 0.0 0.048 13.4 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin DUF2115 PF09888.9 GAX17237.1 - 0.63 10.6 6.7 1.5 9.3 6.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF3435 PF11917.8 GAX17237.1 - 5.4 5.8 14.6 8 5.3 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) TMEM144 PF07857.12 GAX17238.1 - 2.4e-20 72.8 17.9 1.8e-14 53.5 0.1 2.5 2 1 0 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 GAX17238.1 - 3e-11 43.2 19.8 9.8e-08 31.7 5.9 2.9 2 1 0 2 2 2 2 Sugar transport protein Ureide_permease PF07168.11 GAX17238.1 - 0.05 12.3 11.6 0.13 11.0 3.0 2.5 2 0 0 2 2 2 0 Ureide permease SPC25 PF06703.11 GAX17238.1 - 2.7 7.8 4.7 0.62 9.8 0.1 2.3 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) LRR_8 PF13855.6 GAX17239.1 - 4.3e-09 36.0 1.3 0.00019 21.1 1.4 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX17239.1 - 0.01 16.3 3.0 0.65 10.5 0.2 2.7 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX17239.1 - 0.067 13.5 0.6 0.14 12.5 0.6 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Ammonium_transp PF00909.21 GAX17240.1 - 1.5e-105 353.2 25.1 1.7e-105 353.0 25.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Hexapep PF00132.24 GAX17241.1 - 2.1e-07 30.4 4.7 1.4e-05 24.6 1.0 3.6 1 1 2 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAX17241.1 - 2.1e-06 28.2 0.0 4.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 GAX17241.1 - 3e-06 27.0 0.1 1.5e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 GAX17241.1 - 0.0014 16.8 1.1 0.012 13.8 1.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 GAX17241.1 - 0.014 14.4 0.6 0.021 13.8 0.6 1.2 1 0 0 1 1 1 0 L-fucokinase Transposon_TraM PF12508.8 GAX17241.1 - 0.068 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Conjugative transposon, TraM Rieske PF00355.26 GAX17242.1 - 4.2e-12 45.8 0.0 6.1e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 GAX17242.1 - 1.8e-10 40.7 2.1 2.7e-10 40.1 0.2 2.1 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit RNA_pol_A_bac PF01000.26 GAX17244.1 - 2.5e-25 89.0 0.0 6.2e-25 87.7 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAX17244.1 - 1.8e-17 62.5 0.0 3.3e-17 61.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GFA PF04828.14 GAX17245.1 - 0.013 15.8 1.8 1.2 9.6 0.0 3.9 3 1 1 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme GCIP PF13324.6 GAX17246.1 - 2.1e-31 109.5 0.7 3.2e-31 108.9 0.7 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Glutaredoxin2_C PF04399.13 GAX17246.1 - 0.015 15.1 0.3 0.047 13.5 0.2 1.9 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain UPF0565 PF10561.9 GAX17246.1 - 0.049 12.8 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 KIX_2 PF16987.5 GAX17247.1 - 1.3e-07 31.5 1.6 2.4e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 KIX domain DUF4253 PF14062.6 GAX17247.1 - 0.018 15.2 0.4 0.085 13.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Flagellin_C PF00700.21 GAX17247.1 - 0.06 13.7 0.1 0.29 11.5 0.1 2.3 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region ACOX PF01756.19 GAX17247.1 - 0.33 10.5 2.2 6.2 6.3 0.0 3.1 4 0 0 4 4 4 0 Acyl-CoA oxidase Ion_trans PF00520.31 GAX17248.1 - 3.3e-11 42.9 43.2 6.1e-06 25.6 25.3 2.8 2 1 0 2 2 2 2 Ion transport protein Holin_9 PF16936.5 GAX17248.1 - 1.9 8.7 4.7 0.64 10.2 0.4 2.5 2 0 0 2 2 2 0 Putative holin PDEase_I PF00233.19 GAX17249.1 - 3.1e-31 108.9 0.5 2.6e-30 105.9 0.5 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SQHop_cyclase_N PF13249.6 GAX17250.1 - 7.1e-52 176.3 0.0 1.1e-43 149.4 0.1 4.2 4 0 0 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 GAX17250.1 - 2.5e-50 171.4 1.1 3.7e-43 147.8 0.1 3.0 2 2 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 GAX17250.1 - 6.6e-31 105.7 25.5 2.5e-08 33.5 3.3 7.6 6 2 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 GAX17250.1 - 3.7e-05 23.2 0.0 0.64 9.3 0.0 3.4 3 0 0 3 3 3 2 Pectic acid lyase TED_complement PF07678.14 GAX17250.1 - 0.0096 15.0 0.0 0.34 9.9 0.0 3.1 3 0 0 3 3 3 1 A-macroglobulin TED domain F-box-like PF12937.7 GAX17251.1 - 1.3e-05 24.9 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAX17251.1 - 0.00067 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 GAX17251.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 F-box Exo_endo_phos PF03372.23 GAX17252.1 - 6.9e-16 58.5 1.2 1.1e-15 57.8 1.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAX17252.1 - 0.0029 17.4 0.0 0.59 10.0 0.0 2.9 2 1 0 2 2 2 2 Endonuclease-reverse transcriptase adh_short PF00106.25 GAX17253.1 - 2.7e-44 151.0 0.0 3.7e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX17253.1 - 2.5e-34 118.9 0.2 3.2e-34 118.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX17253.1 - 5.8e-18 65.4 0.2 9.6e-18 64.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX17253.1 - 0.00032 20.3 0.1 0.0026 17.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAX17253.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 GAX17253.1 - 0.026 13.8 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Microtub_bd PF16796.5 GAX17253.1 - 0.029 14.3 0.1 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding Eno-Rase_NADH_b PF12242.8 GAX17253.1 - 0.093 12.5 1.1 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Nuf2 PF03800.14 GAX17255.1 - 7.6e-33 113.6 0.0 7.6e-33 113.6 0.0 2.9 3 1 0 3 3 3 1 Nuf2 family DUF2999 PF11212.8 GAX17255.1 - 0.042 14.1 3.2 1.8 8.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) RNase_T PF00929.24 GAX17256.1 - 4.5e-07 30.6 0.0 9.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAX17256.1 - 0.0028 17.4 0.2 0.015 15.0 0.2 2.1 1 1 0 1 1 1 1 3'-5' exonuclease CAF1 PF04857.20 GAX17256.1 - 0.92 8.6 0.0 0.92 8.6 0.0 2.9 2 1 1 3 3 3 0 CAF1 family ribonuclease DNA_ligase_A_M PF01068.21 GAX17257.1 - 2.3e-22 79.7 0.0 2e-18 66.8 0.0 3.1 3 1 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAX17257.1 - 9.4e-21 74.9 0.0 1.7e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 GAX17257.1 - 3.4e-05 24.2 0.0 0.0002 21.7 0.0 2.3 1 1 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 GAX17257.1 - 5.2e-05 23.8 0.0 0.0021 18.6 0.0 2.9 1 1 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pro_isomerase PF00160.21 GAX17259.1 - 2.2e-15 57.3 0.0 3.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNase PF00565.17 GAX17260.1 - 4.5e-17 62.5 0.0 7.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MCM_bind PF09739.9 GAX17260.1 - 0.19 10.1 1.1 0.26 9.7 1.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor TFIIA PF03153.13 GAX17261.1 - 0.039 14.0 8.5 0.047 13.7 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.31 GAX17262.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 DnaJ domain Guanylate_cyc PF00211.20 GAX17266.1 - 3.6e-12 46.3 0.1 7e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain IQ PF00612.27 GAX17266.1 - 0.011 15.4 1.1 0.035 13.9 1.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif FAM60A PF15396.6 GAX17266.1 - 0.068 13.2 0.2 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein Family FAM60A PhyH PF05721.13 GAX17267.1 - 1.2e-08 35.5 0.9 4e-08 33.8 0.1 2.3 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Cellulase PF00150.18 GAX17268.1 - 0.0029 17.1 0.7 0.64 9.4 0.0 3.5 2 2 2 4 4 4 3 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 GAX17269.1 - 1.6e-60 204.7 1.9 6.1e-59 199.5 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17269.1 - 6.4e-30 104.3 0.0 1.3e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX17269.1 - 1.5e-17 63.8 0.5 1.5e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX17269.1 - 4e-14 51.3 0.3 0.0022 17.8 0.1 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 GAX17269.1 - 4.1e-14 51.0 0.1 0.0059 16.1 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAX17269.1 - 6.6e-14 51.5 0.2 4.1e-07 29.8 0.0 3.8 2 2 2 4 4 4 2 EF-hand domain pair Kdo PF06293.14 GAX17269.1 - 4.2e-05 23.0 0.0 0.00019 20.9 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX17269.1 - 4.9e-05 22.3 0.0 7.2e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_5 PF13202.6 GAX17269.1 - 0.00012 21.4 0.4 1.3 8.6 0.1 3.6 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 GAX17269.1 - 0.00025 20.5 0.1 0.0011 18.3 0.1 2.0 1 1 0 1 1 1 1 Kinase-like DUF1296 PF06972.11 GAX17269.1 - 0.0015 18.6 0.0 0.0036 17.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) Haspin_kinase PF12330.8 GAX17269.1 - 0.0029 16.6 0.1 0.0046 15.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 GAX17270.1 - 4.5e-15 56.0 0.1 6.8e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAX17270.1 - 6.5e-05 23.3 2.8 0.001 19.5 2.8 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAX17270.1 - 0.051 13.9 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 GAX17270.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain MIF4G PF02854.19 GAX17271.1 - 4e-05 23.4 0.0 0.17 11.5 0.0 2.6 2 1 0 2 2 2 2 MIF4G domain MA3 PF02847.17 GAX17271.1 - 0.00056 19.9 0.0 0.031 14.2 0.0 2.7 2 0 0 2 2 2 1 MA3 domain DHBP_synthase PF00926.19 GAX17273.1 - 1.7e-76 256.0 0.6 2.7e-76 255.4 0.6 1.3 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 GAX17273.1 - 7.2e-56 188.3 0.0 2.2e-55 186.7 0.0 1.8 2 0 0 2 2 2 1 GTP cyclohydrolase II TPR_12 PF13424.6 GAX17274.1 - 1.8e-14 53.7 6.2 4.4e-07 30.1 0.9 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17274.1 - 4e-13 48.6 1.5 0.024 14.5 0.4 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17274.1 - 1e-10 40.9 5.2 0.02 15.0 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17274.1 - 4.1e-09 35.8 4.1 0.037 14.1 0.6 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17274.1 - 1.9e-06 27.6 5.2 0.038 14.2 0.4 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17274.1 - 4.2e-05 24.0 9.0 0.5 11.3 0.7 5.0 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX17274.1 - 0.00013 21.5 5.3 0.00022 20.7 5.3 1.4 1 0 0 1 1 1 1 MalT-like TPR region DUF2225 PF09986.9 GAX17274.1 - 0.0003 20.6 6.4 0.00089 19.0 3.8 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.6 GAX17274.1 - 0.00058 20.5 8.2 0.022 15.4 2.7 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17274.1 - 0.0013 18.6 5.7 13 5.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX17274.1 - 0.0038 16.9 7.0 4.3 7.1 0.0 4.0 3 1 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 GAX17274.1 - 0.012 15.8 2.5 19 5.5 0.0 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAX17274.1 - 0.022 14.8 2.7 0.036 14.1 1.7 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 GAX17274.1 - 0.31 11.5 3.7 1.1 9.8 3.7 2.0 1 1 0 1 1 1 0 Alkyl sulfatase dimerisation CortBP2 PF09727.9 GAX17274.1 - 0.66 9.9 7.0 0.093 12.6 2.1 2.1 2 1 0 2 2 2 0 Cortactin-binding protein-2 MIT PF04212.18 GAX17274.1 - 2 8.6 12.4 2.3 8.4 1.7 3.7 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain Spectrin PF00435.21 GAX17274.1 - 3.8 8.0 10.9 0.72 10.4 0.6 3.0 3 0 0 3 3 3 0 Spectrin repeat TPR_6 PF13174.6 GAX17274.1 - 6.1 7.7 11.4 16 6.4 0.1 4.6 4 1 0 4 4 3 0 Tetratricopeptide repeat PB1 PF00564.24 GAX17275.1 - 4.1e-12 45.8 0.1 6.9e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 PB1 domain Myosin_head PF00063.21 GAX17276.1 - 5.9e-194 646.1 0.4 6.7e-177 589.7 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) DNA_ligase_aden PF01653.18 GAX17277.1 - 1.3e-46 159.2 0.0 2.4e-46 158.3 0.0 1.4 1 1 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 GAX17277.1 - 2.8e-23 81.6 1.8 5.1e-23 80.8 1.8 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain BRCT PF00533.26 GAX17277.1 - 1.3e-10 41.5 0.0 3.2e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAX17277.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain HHH_2 PF12826.7 GAX17277.1 - 0.016 15.3 0.0 0.054 13.6 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif DNA_ligase_ZBD PF03119.16 GAX17277.1 - 0.019 14.9 2.0 0.048 13.7 2.0 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain XLF PF09302.11 GAX17277.1 - 0.038 14.2 0.3 0.1 12.8 0.3 1.7 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Cellulase PF00150.18 GAX17278.1 - 6.1e-10 39.0 0.2 1.1e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TarH PF02203.15 GAX17278.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue ATP-sulfurylase PF01747.17 GAX17280.1 - 1e-70 237.5 0.0 1.5e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 GAX17280.1 - 3.9e-41 140.4 0.0 5.4e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain MFS_1 PF07690.16 GAX17281.1 - 8.6e-31 107.1 37.9 8.6e-31 107.1 37.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX17281.1 - 9.1e-08 31.4 25.6 5.6e-07 28.8 25.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAX17281.1 - 2.6e-07 29.9 27.5 5.5e-07 28.8 9.5 2.4 1 1 1 2 2 2 2 MFS_1 like family Pkinase PF00069.25 GAX17282.1 - 6e-12 45.5 0.0 9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17282.1 - 1.2e-09 37.8 0.0 6.1e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_tranf_2_4 PF13704.6 GAX17283.1 - 4.7e-05 23.8 0.6 0.00011 22.6 0.6 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 cobW PF02492.19 GAX17284.1 - 2.4e-48 164.1 0.1 3.1e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX17284.1 - 1.1e-21 76.5 0.0 1.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAX17284.1 - 0.0015 18.4 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 GAX17284.1 - 0.016 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 GAX17284.1 - 0.051 13.8 0.2 0.28 11.5 0.0 2.1 2 1 0 3 3 3 0 AAA domain dNK PF01712.19 GAX17284.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase ATPase_2 PF01637.18 GAX17284.1 - 0.069 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAX17284.1 - 0.07 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 GAX17284.1 - 0.086 12.7 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 GAX17284.1 - 0.16 11.9 0.1 0.81 9.6 0.1 2.0 2 0 0 2 2 2 0 NTPase YvbH_ext PF11724.8 GAX17285.1 - 0.04 14.2 0.2 0.098 13.0 0.2 1.7 1 1 0 1 1 1 0 YvbH-like oligomerisation region DUF5094 PF17015.5 GAX17285.1 - 0.12 12.5 4.5 0.14 12.3 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Abhydrolase_6 PF12697.7 GAX17287.1 - 2.8e-08 34.6 0.7 3.5e-08 34.3 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX17287.1 - 0.00071 19.3 0.1 0.67 9.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX17287.1 - 0.0019 17.5 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAX17287.1 - 0.18 11.3 0.1 0.28 10.6 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family FYVE PF01363.21 GAX17288.1 - 3.6e-20 71.9 1.2 9.8e-20 70.5 1.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger zf-CRD PF17979.1 GAX17288.1 - 0.24 11.5 4.7 0.2 11.7 1.0 2.8 3 0 0 3 3 3 0 Cysteine rich domain with multizinc binding regions IBR PF01485.21 GAX17288.1 - 0.47 10.7 7.9 1.5 9.1 7.9 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Fer2_3 PF13085.6 GAX17289.1 - 1.9e-31 108.3 0.0 3.2e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 GAX17289.1 - 1.6e-09 38.2 4.9 1.6e-09 38.2 4.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAX17289.1 - 2e-08 34.5 7.1 2e-08 34.5 7.1 3.0 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAX17289.1 - 6.6e-08 32.6 3.6 6.6e-08 32.6 3.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 GAX17289.1 - 0.0023 17.8 3.1 0.004 17.1 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 GAX17289.1 - 0.0029 18.2 8.1 0.0029 18.2 8.1 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAX17289.1 - 0.0055 16.8 7.6 0.0055 16.8 7.6 2.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 GAX17289.1 - 0.076 13.2 6.3 0.41 10.8 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Mitofilin PF09731.9 GAX17290.1 - 0.00027 19.9 35.0 0.00027 19.9 35.0 2.0 1 1 1 2 2 2 1 Mitochondrial inner membrane protein DUF3584 PF12128.8 GAX17290.1 - 0.0053 14.3 39.6 0.0067 14.0 39.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Tup_N PF08581.10 GAX17290.1 - 0.01 16.1 14.1 0.01 16.1 14.1 3.3 3 1 0 3 3 3 0 Tup N-terminal Effector_1 PF04518.12 GAX17290.1 - 0.011 14.9 8.3 0.011 14.9 8.3 2.2 2 0 0 2 2 2 0 Effector from type III secretion system DASH_Dam1 PF08653.10 GAX17290.1 - 0.077 12.8 6.8 4.2 7.2 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF883 PF05957.13 GAX17290.1 - 0.53 10.9 31.7 0.1 13.2 3.1 4.1 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) DASH_Dad4 PF08650.10 GAX17290.1 - 2.4 8.2 13.0 0.5 10.4 6.0 3.1 2 1 1 3 3 3 0 DASH complex subunit Dad4 DUF4795 PF16043.5 GAX17290.1 - 3.4 7.2 48.4 0.87 9.1 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) IZUMO PF15005.6 GAX17290.1 - 5.6 7.5 28.9 0.046 14.2 12.7 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated zf-RING_2 PF13639.6 GAX17291.1 - 7.3e-12 45.4 5.3 1.2e-11 44.8 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX17291.1 - 1.3e-10 40.9 3.7 2.2e-10 40.2 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX17291.1 - 8.9e-09 34.9 3.9 8.9e-09 34.9 3.9 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX17291.1 - 2.4e-08 33.7 4.3 3.9e-08 33.0 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX17291.1 - 4.2e-08 33.4 7.1 1.3e-07 31.8 7.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX17291.1 - 4.8e-08 32.9 3.3 6e-08 32.6 0.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX17291.1 - 3.8e-07 29.9 3.1 5.9e-07 29.3 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX17291.1 - 5.5e-05 22.9 4.5 9.2e-05 22.2 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX17291.1 - 0.00071 19.6 3.0 0.0017 18.4 3.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAX17291.1 - 0.014 15.3 4.9 0.026 14.4 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 GAX17291.1 - 0.054 13.5 1.0 0.17 12.0 1.0 1.8 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 GAX17291.1 - 0.064 13.4 5.0 0.14 12.3 5.0 1.5 1 0 0 1 1 1 0 RING-variant domain CBP4 PF07960.11 GAX17291.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 CBP4 zf-RING_6 PF14835.6 GAX17291.1 - 0.16 11.8 1.6 0.38 10.7 1.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 GAX17291.1 - 0.22 11.1 5.3 0.36 10.5 5.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RecR PF02132.15 GAX17291.1 - 0.65 9.6 3.0 2.3 7.9 0.4 2.4 2 0 0 2 2 2 0 RecR protein PHD PF00628.29 GAX17291.1 - 0.65 9.9 3.4 1.4 8.9 3.4 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 GAX17291.1 - 0.76 9.6 4.3 2.7 7.9 4.3 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAX17291.1 - 1.1 9.4 4.8 5.5 7.2 4.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 GAX17291.1 - 4.8 7.4 7.6 37 4.6 7.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain RuvX PF03652.15 GAX17292.1 - 0.00032 21.1 0.0 0.00048 20.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction resolvase Sulfotransfer_2 PF03567.14 GAX17293.1 - 8.5e-07 29.1 0.8 2.3e-06 27.7 0.8 1.8 1 1 0 1 1 1 1 Sulfotransferase family Glyco_tranf_2_4 PF13704.6 GAX17294.1 - 4.4e-08 33.5 1.5 4.8e-07 30.2 0.3 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX17294.1 - 0.0083 15.8 1.1 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 92 PDZ PF00595.24 GAX17296.1 - 4.1e-09 36.7 0.1 6.6e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX17296.1 - 1.3e-07 31.3 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX17296.1 - 0.0002 21.6 0.0 0.00036 20.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GFO_IDH_MocA PF01408.22 GAX17298.1 - 1.3e-06 29.2 0.0 3.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KaiA PF07688.12 GAX17298.1 - 0.01 16.0 0.1 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 KaiA C-terminal domain CoA_binding_2 PF13380.6 GAX17298.1 - 0.035 14.6 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain Pkinase PF00069.25 GAX17299.1 - 2.2e-56 191.1 0.1 1.8e-54 184.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17299.1 - 2.9e-30 105.4 0.0 6.5e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX17299.1 - 1.4e-16 60.6 4.5 2.2e-10 40.8 0.9 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAX17299.1 - 1.4e-11 43.4 4.5 0.0019 18.0 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 GAX17299.1 - 1.5e-11 43.0 6.8 0.027 14.0 0.4 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAX17299.1 - 1.2e-10 41.1 0.6 7.4e-05 22.5 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair Pkinase_fungal PF17667.1 GAX17299.1 - 1.3e-06 27.5 0.0 1.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX17299.1 - 0.00018 21.0 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX17299.1 - 0.00064 19.1 0.0 0.0023 17.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAX17299.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.20 GAX17299.1 - 0.025 13.9 0.0 0.064 12.6 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase Haspin_kinase PF12330.8 GAX17299.1 - 0.037 13.0 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain WD40_alt PF14077.6 GAX17299.1 - 0.043 13.7 0.7 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif SPARC_Ca_bdg PF10591.9 GAX17299.1 - 0.14 12.4 0.1 0.86 9.9 0.0 2.1 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 GAX17300.1 - 2.4e-11 43.9 0.1 3.6e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair COPI_assoc PF08507.10 GAX17300.1 - 4e-10 39.8 8.2 6.3e-10 39.2 8.2 1.3 1 0 0 1 1 1 1 COPI associated protein EF-hand_6 PF13405.6 GAX17300.1 - 6.7e-06 25.6 0.1 0.0011 18.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain Cg6151-P PF10233.9 GAX17300.1 - 6.8e-05 23.2 5.9 0.00013 22.3 5.9 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P EF-hand_1 PF00036.32 GAX17300.1 - 0.00021 20.6 0.0 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GAX17300.1 - 0.0024 17.3 0.1 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 GAX17300.1 - 0.027 14.8 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region TPR_1 PF00515.28 GAX17302.1 - 1.2e-09 37.6 8.7 0.0032 17.2 0.1 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17302.1 - 4.8e-09 35.7 6.0 0.0085 16.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX17302.1 - 3.8e-06 27.1 3.0 6.3e-05 23.2 0.9 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17302.1 - 3.4e-05 23.7 3.6 0.12 12.6 0.1 3.4 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX17302.1 - 0.00016 22.1 2.3 0.00016 22.1 2.3 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX17302.1 - 0.00025 20.7 4.7 0.047 13.4 0.1 2.8 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 GAX17302.1 - 0.00028 21.5 3.6 0.0032 18.1 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX17302.1 - 0.00082 19.4 1.6 0.022 14.8 0.7 2.5 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 GAX17302.1 - 0.0082 16.9 6.8 0.56 11.2 0.1 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX17302.1 - 0.015 15.5 0.4 0.042 14.1 0.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CAP_C PF08603.11 GAX17302.1 - 0.017 14.8 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal TPR_10 PF13374.6 GAX17302.1 - 0.017 15.0 0.5 0.86 9.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAX17302.1 - 0.019 15.3 0.4 0.019 15.3 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX17302.1 - 0.033 14.3 0.2 0.071 13.3 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX17302.1 - 0.11 13.0 0.1 11 6.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1376 PF07120.11 GAX17302.1 - 0.15 12.4 1.5 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) TBCC PF07986.12 GAX17302.1 - 0.19 11.5 1.9 0.39 10.5 1.9 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C TPR_6 PF13174.6 GAX17302.1 - 0.2 12.4 3.2 0.99 10.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Hexapep PF00132.24 GAX17303.1 - 2.9e-14 52.1 3.3 5e-10 38.7 0.3 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 GAX17303.1 - 3.1e-13 50.0 0.2 8e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 GAX17303.1 - 1.6e-07 31.0 7.0 2.7e-07 30.2 0.5 2.4 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF3510 PF12022.8 GAX17303.1 - 0.17 12.3 0.5 2.5 8.5 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Thiolase_N PF00108.23 GAX17304.1 - 4e-70 236.1 0.5 6.1e-70 235.5 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAX17304.1 - 1.9e-35 121.2 0.0 5.5e-35 119.7 0.0 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAX17304.1 - 0.0024 17.5 2.9 0.0058 16.2 1.4 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 GAX17304.1 - 0.0086 14.8 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 GAX17304.1 - 0.12 12.2 1.5 2.7 7.9 0.8 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LOR PF04525.12 GAX17306.1 - 3.1e-11 43.2 0.0 4.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 LURP-one-related DMAP_binding PF06464.11 GAX17307.1 - 0.2 12.5 3.5 1.8 9.4 2.3 2.8 2 1 0 2 2 2 0 DMAP1-binding Domain HAD PF12710.7 GAX17308.1 - 4.3e-16 59.9 0.0 7.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX17308.1 - 5.3e-12 46.5 0.7 4.5e-11 43.4 0.7 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAX17308.1 - 4.3e-09 36.1 0.0 6.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 GAX17308.1 - 0.003 17.1 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF1378 PF07125.11 GAX17308.1 - 0.23 11.6 0.5 1.2 9.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1378) YtfJ_HI0045 PF09695.10 GAX17310.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) dsrm PF00035.26 GAX17311.1 - 7.1e-12 45.9 1.7 2.6e-07 31.3 0.0 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif MIR PF02815.19 GAX17311.1 - 0.065 13.1 0.7 0.13 12.1 0.7 1.4 1 0 0 1 1 1 0 MIR domain Pkinase PF00069.25 GAX17312.1 - 2.2e-11 43.6 0.0 1.3e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17312.1 - 7.6e-10 38.5 0.0 2.3e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 GAX17313.1 - 7.6e-09 35.2 6.1 5.9e-07 29.2 0.5 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX17313.1 - 2.8e-08 33.9 7.3 0.00067 20.0 4.4 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX17313.1 - 6e-05 23.0 1.3 0.71 10.7 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat ATP19 PF11022.8 GAX17313.1 - 0.0078 16.6 0.1 0.024 15.0 0.1 1.8 2 0 0 2 2 2 1 ATP synthase subunit K LRR_6 PF13516.6 GAX17313.1 - 0.032 14.3 1.9 3 8.1 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 GAX17313.1 - 0.056 12.9 0.1 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat TMEM154 PF15102.6 GAX17313.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family LRRNT_2 PF08263.12 GAX17313.1 - 0.097 13.0 5.0 0.23 11.8 5.0 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Peptidase_S49_N PF08496.10 GAX17313.1 - 0.13 12.4 0.4 0.22 11.6 0.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UL42 PF17638.2 GAX17313.1 - 2 8.4 5.3 5.1 7.1 5.3 1.7 1 1 0 1 1 1 0 HCMV UL42 TLC PF03219.14 GAX17314.1 - 4.9e-16 58.5 12.4 2.2e-13 49.8 12.4 2.9 1 1 0 1 1 1 1 TLC ATP/ADP transporter HPP PF04982.13 GAX17314.1 - 0.59 10.3 5.8 5.4 7.2 0.8 3.5 3 0 0 3 3 3 0 HPP family mTERF PF02536.14 GAX17317.1 - 2.7e-17 62.7 0.3 6.4e-17 61.4 0.3 1.6 1 0 0 1 1 1 1 mTERF Utp12 PF04003.12 GAX17317.1 - 0.64 10.3 3.4 1.9 8.9 3.4 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family HpaP PF09483.10 GAX17317.1 - 2.8 8.3 5.4 1.8 8.9 1.1 2.8 3 0 0 3 3 3 0 Type III secretion protein (HpaP) NAD_binding_10 PF13460.6 GAX17318.1 - 1.5e-21 77.1 0.0 4.2e-12 46.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 GAX17318.1 - 6.3e-14 52.1 0.0 2.5e-12 46.9 0.0 2.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 GAX17318.1 - 4.4e-06 26.3 0.0 9.3e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX17318.1 - 1.9e-05 23.8 0.1 3.5e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 GAX17318.1 - 3.4e-05 23.8 0.3 0.00013 21.9 0.2 2.0 2 0 0 2 2 2 1 KR domain CIA30 PF08547.12 GAX17318.1 - 0.0006 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) adh_short PF00106.25 GAX17318.1 - 0.0087 15.5 0.7 0.018 14.5 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX17318.1 - 0.0096 16.2 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAX17318.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 GAX17318.1 - 0.021 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus RmlD_sub_bind PF04321.17 GAX17318.1 - 0.098 11.7 0.0 6.8 5.7 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GAX17318.1 - 0.1 12.0 0.2 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PA26 PF04636.13 GAX17318.1 - 0.58 9.0 3.1 0.97 8.3 3.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Caudo_TAP PF02413.17 GAX17318.1 - 0.6 10.3 4.2 0.42 10.8 1.3 2.2 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK CDC27 PF09507.10 GAX17319.1 - 2.1e-17 63.6 21.4 2.5e-17 63.4 21.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PBP1_TM PF14812.6 GAX17319.1 - 0.035 14.5 7.8 4.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_49 PF13896.6 GAX17320.1 - 2.1e-39 135.8 1.2 2.9e-35 122.2 0.1 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan peroxidase PF00141.23 GAX17321.1 - 8.3e-46 156.5 0.0 1.2e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF3309 PF11752.8 GAX17323.1 - 0.44 10.6 3.1 0.72 9.9 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Tubulin PF00091.25 GAX17324.1 - 9e-57 192.5 0.0 1.5e-56 191.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAX17324.1 - 4.8e-39 133.4 0.1 7e-39 132.9 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAX17324.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 GAX17324.1 - 0.032 13.4 0.0 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 Tubulin like Glyco_hydro_101 PF12905.7 GAX17325.1 - 0.051 13.0 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase HEAT PF02985.22 GAX17326.1 - 0.013 15.7 5.7 6.3 7.3 0.0 6.0 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.7 GAX17326.1 - 0.041 13.9 0.1 2.6 8.0 0.0 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF5463 PF17551.2 GAX17326.1 - 0.29 11.1 1.9 0.35 10.8 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5463) Condensation PF00668.20 GAX17327.1 - 4.2e-06 25.7 0.5 0.0002 20.2 0.0 3.0 3 1 0 3 3 3 2 Condensation domain AATase PF07247.12 GAX17327.1 - 2.1e-05 23.3 1.5 0.31 9.6 0.0 3.4 3 1 0 3 3 3 2 Alcohol acetyltransferase O-FucT PF10250.9 GAX17328.1 - 3.5e-47 161.7 0.6 4.8e-47 161.3 0.6 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_tran_28_C PF04101.16 GAX17329.1 - 2.7e-25 89.3 0.1 3.3e-25 89.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain O-FucT PF10250.9 GAX17330.1 - 2.8e-53 181.8 0.5 3.5e-53 181.5 0.5 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Methyltransf_4 PF02390.17 GAX17330.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase O-FucT PF10250.9 GAX17331.1 - 1e-52 180.0 1.0 1.4e-52 179.5 1.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pcc1 PF09341.10 GAX17333.1 - 2.5e-17 62.8 0.1 2.8e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 WD40 PF00400.32 GAX17334.1 - 9.1e-10 39.0 3.9 0.39 11.7 0.0 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17334.1 - 8.5e-06 26.0 0.0 0.086 13.1 0.0 3.9 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PAP_fibrillin PF04755.12 GAX17334.1 - 0.00071 19.6 0.0 0.0054 16.7 0.0 2.4 2 1 0 2 2 2 1 PAP_fibrillin WD40_like PF17005.5 GAX17334.1 - 0.0018 17.6 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 GAX17334.1 - 0.013 14.5 0.1 3.6 6.5 0.0 3.4 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mcl1_mid PF12341.8 GAX17334.1 - 0.093 12.1 0.0 5 6.4 0.0 2.4 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Glyco_hydro_38N PF01074.22 GAX17335.1 - 2.4e-69 233.9 5.1 3.5e-69 233.4 5.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAX17335.1 - 1.6e-39 136.2 0.0 2.4e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAX17335.1 - 4.4e-17 62.0 0.0 1.2e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAX17335.1 - 0.004 17.2 0.0 0.0096 16.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain SPOB_ab PF14682.6 GAX17335.1 - 0.1 12.7 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal GxGYxYP_C PF14323.6 GAX17336.1 - 0.061 13.2 0.0 10 5.9 0.0 2.3 2 0 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain UPF0020 PF01170.18 GAX17337.1 - 4e-14 52.8 0.1 4.7e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 AviRa PF11599.8 GAX17337.1 - 0.0061 16.0 0.0 0.026 14.0 0.0 2.0 2 1 1 3 3 3 1 RRNA methyltransferase AviRa Methyltransf_25 PF13649.6 GAX17337.1 - 0.0095 16.6 0.0 0.024 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GAX17337.1 - 0.02 14.6 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 DNA methylase Methyltransf_11 PF08241.12 GAX17337.1 - 0.048 14.3 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S49 PF01343.18 GAX17338.1 - 1.2e-27 96.8 0.0 2.3e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 GAX17338.1 - 0.0001 22.4 1.9 0.0029 17.7 0.2 3.1 2 1 0 2 2 2 1 Peptidase family S49 N-terminal SDH_sah PF01972.16 GAX17338.1 - 0.087 11.8 0.1 0.29 10.1 0.1 1.7 1 1 0 2 2 2 0 Serine dehydrogenase proteinase DUF1387 PF07139.11 GAX17338.1 - 4.4 6.9 8.8 7 6.3 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) FA_desaturase PF00487.24 GAX17339.1 - 4.2e-19 69.4 18.5 7.6e-19 68.5 18.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Asr PF06392.11 GAX17340.1 - 0.043 14.2 3.8 0.043 14.2 3.8 2.2 2 0 0 2 2 2 0 Acid shock protein repeat DUF1269 PF06897.12 GAX17340.1 - 0.93 9.8 7.4 1.3 9.3 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) TRAPP PF04051.16 GAX17341.1 - 2e-39 134.6 0.0 2.3e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3624 PF12292.8 GAX17341.1 - 0.13 12.7 0.0 2 8.9 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3624) Epimerase PF01370.21 GAX17343.1 - 0.0015 18.0 0.0 0.0056 16.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Aldedh PF00171.22 GAX17344.1 - 2.2e-155 517.7 0.1 2.5e-155 517.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAX17344.1 - 0.00015 21.3 0.1 0.0095 15.4 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Pkinase PF00069.25 GAX17345.1 - 1.3e-52 178.8 0.0 2e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17345.1 - 4.7e-22 78.5 0.0 1e-21 77.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 GAX17345.1 - 0.00051 20.5 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 GAX17345.1 - 0.0035 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAX17345.1 - 0.043 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAX17345.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GlgX_C PF18390.1 GAX17345.1 - 0.17 11.7 0.0 0.49 10.2 0.0 1.7 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain Trypsin PF00089.26 GAX17346.1 - 1.3e-52 178.8 0.0 1.8e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX17346.1 - 5.6e-08 33.8 0.5 2.8e-07 31.6 0.1 2.3 2 1 0 2 2 2 1 Trypsin-like peptidase domain Epimerase PF01370.21 GAX17347.1 - 9.8e-26 90.7 0.0 1.8e-25 89.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX17347.1 - 2.3e-16 60.1 0.0 1.5e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX17347.1 - 7e-05 22.1 0.0 0.021 14.0 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 GAX17347.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAGK_cat PF00781.24 GAX17347.1 - 0.024 14.2 0.0 0.074 12.7 0.0 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Yae1_N PF09811.9 GAX17348.1 - 0.47 10.2 11.5 6.3 6.6 0.0 6.6 7 2 1 8 8 8 0 Essential protein Yae1, N terminal Yae1_N PF09811.9 GAX17349.1 - 0.001 18.7 2.3 0.16 11.7 0.1 4.4 4 1 0 5 5 5 2 Essential protein Yae1, N terminal Yae1_N PF09811.9 GAX17351.1 - 1.5 8.6 7.5 23 4.8 0.1 5.2 6 1 0 6 6 6 0 Essential protein Yae1, N terminal HHH_8 PF14716.6 GAX17353.1 - 2.8e-11 43.6 1.6 3.3e-11 43.4 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain zf-PARP PF00645.18 GAX17353.1 - 2.3e-06 28.4 0.0 2.3e-06 28.4 0.0 3.0 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.12 GAX17353.1 - 0.0077 16.0 1.2 0.0077 16.0 1.2 2.2 2 0 0 2 2 2 1 PADR1 (NUC008) domain Activator-TraM PF11657.8 GAX17353.1 - 0.047 13.5 0.6 0.047 13.5 0.6 2.1 2 1 0 2 2 2 0 Transcriptional activator TraM DUF3818 PF12825.7 GAX17353.1 - 0.077 12.0 8.5 0.081 11.9 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) vATP-synt_AC39 PF01992.16 GAX17354.1 - 7.2e-108 361.1 0.1 8.1e-108 360.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit G-alpha PF00503.20 GAX17355.1 - 9.6e-95 317.7 0.0 1.1e-94 317.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAX17355.1 - 4.1e-15 55.7 0.8 6.7e-12 45.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAX17355.1 - 0.00011 22.5 0.1 0.43 10.8 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAX17355.1 - 0.00021 20.7 0.2 0.046 13.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAX17355.1 - 0.0054 16.8 0.0 0.39 10.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX17355.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_12 PF13424.6 GAX17356.1 - 2.6e-33 114.2 15.5 1.6e-13 50.7 4.5 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17356.1 - 4.8e-19 67.3 13.3 0.002 17.9 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17356.1 - 5.1e-16 57.4 14.6 0.0013 18.7 0.0 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17356.1 - 6.5e-14 50.9 2.3 0.00029 20.7 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17356.1 - 1.2e-13 50.0 8.5 0.04 14.1 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17356.1 - 7.8e-13 47.9 12.4 0.0001 22.1 0.1 5.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17356.1 - 4.1e-11 42.7 7.4 0.016 16.0 0.0 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX17356.1 - 5.1e-11 42.5 4.2 5.4e-11 42.4 1.1 2.4 2 1 0 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 GAX17356.1 - 1.6e-10 40.4 2.8 0.0011 18.6 0.0 5.4 5 0 0 5 5 5 2 TPR repeat RPN7 PF10602.9 GAX17356.1 - 0.0017 18.1 0.3 0.58 9.9 0.1 3.2 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_16 PF13432.6 GAX17356.1 - 0.0053 17.4 10.1 0.024 15.3 2.1 4.8 5 2 1 6 6 6 2 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX17356.1 - 0.0069 16.4 3.5 1.7 8.8 0.0 4.1 4 1 0 4 4 3 1 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 GAX17356.1 - 0.029 15.0 5.9 0.092 13.4 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat SPO22 PF08631.10 GAX17356.1 - 0.049 13.1 1.9 7.1 6.0 0.1 3.2 2 1 2 4 4 4 0 Meiosis protein SPO22/ZIP4 like TPR_9 PF13371.6 GAX17356.1 - 0.096 12.8 0.5 9 6.5 0.0 3.4 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX17356.1 - 0.12 12.9 0.0 33 5.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 GAX17356.1 - 0.13 12.4 1.6 12 6.0 0.0 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 GAX17356.1 - 0.94 9.9 4.0 21 5.5 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX17356.1 - 0.95 10.2 6.3 8.2 7.3 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 GAX17357.1 - 8.9e-19 67.9 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX17357.1 - 2.8e-16 60.0 0.0 4.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX17357.1 - 1.5e-11 44.9 0.0 2.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX17357.1 - 1.7e-11 43.9 0.0 2.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAX17357.1 - 7.3e-10 38.8 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX17357.1 - 4e-05 23.5 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAX17357.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Mito_carr PF00153.27 GAX17358.1 - 3.1e-65 216.1 2.6 9.7e-22 76.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Lipase_GDSL_2 PF13472.6 GAX17359.1 - 3.6e-16 60.1 0.0 9.2e-16 58.7 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX17359.1 - 7.1e-13 49.0 0.0 1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SNase PF00565.17 GAX17360.1 - 1e-19 71.0 0.0 1.9e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Choline_transpo PF04515.12 GAX17361.1 - 3.1e-51 174.5 13.9 3.1e-51 174.5 13.9 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter G0-G1_switch_2 PF15103.6 GAX17361.1 - 0.13 12.7 0.7 0.6 10.6 0.0 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Glyoxalase PF00903.25 GAX17362.1 - 0.0013 19.0 0.0 0.56 10.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily His_Phos_1 PF00300.22 GAX17363.1 - 7.7e-09 35.5 0.0 4.5e-06 26.5 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Epimerase PF01370.21 GAX17364.1 - 3e-43 148.0 0.0 3.6e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX17364.1 - 8.1e-29 101.1 0.0 2.4e-27 96.2 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAX17364.1 - 1.1e-11 44.3 0.0 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAX17364.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAX17364.1 - 0.00031 20.0 0.0 0.33 10.1 0.0 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.13 GAX17364.1 - 0.00048 19.8 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 GAX17364.1 - 0.0017 17.8 0.1 0.0025 17.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GAX17364.1 - 0.0046 16.2 0.0 0.041 13.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 GAX17364.1 - 0.006 15.7 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 GAX17364.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAX17364.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 GAX17364.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 GAX17364.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Pyr_redox PF00070.27 GAX17364.1 - 0.17 12.5 0.1 0.49 11.0 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAX17364.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain PPR_2 PF13041.6 GAX17365.1 - 2.3e-24 85.3 7.0 3.4e-05 24.0 0.0 8.2 7 2 1 8 8 8 5 PPR repeat family PPR_3 PF13812.6 GAX17365.1 - 3.4e-16 59.1 4.5 1.7e-05 24.8 0.2 7.2 5 3 1 6 6 6 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX17365.1 - 3.2e-14 52.3 9.3 0.027 14.2 0.0 9.2 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 GAX17365.1 - 4.3e-11 42.6 4.7 0.0049 16.3 0.1 4.9 1 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX17365.1 - 8.4e-11 41.4 11.7 0.19 12.1 0.0 9.9 10 2 0 10 10 10 2 PPR repeat RPM2 PF08579.11 GAX17365.1 - 0.00018 21.9 3.4 0.087 13.2 0.0 4.4 3 2 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) Nipped-B_C PF12830.7 GAX17365.1 - 0.045 13.7 0.0 0.2 11.6 0.0 2.0 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus US6 PF17616.2 GAX17365.1 - 0.16 11.9 0.3 4.5 7.2 0.1 2.7 2 0 0 2 2 2 0 Viral unique short region 6 KH_8 PF17903.1 GAX17366.1 - 6e-31 106.4 0.0 1.5e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 GAX17366.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 KH domain Sec63 PF02889.16 GAX17367.1 - 2.2e-32 112.2 0.2 3e-32 111.8 0.2 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 GAX17367.1 - 6.5e-21 74.2 0.6 2.8e-20 72.2 0.1 2.4 2 0 0 2 2 2 1 DnaJ domain Coprogen_oxidas PF01218.18 GAX17369.1 - 1.1e-82 277.1 0.0 1.5e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Spherulin4 PF12138.8 GAX17369.1 - 0.11 12.1 0.0 0.72 9.4 0.0 2.0 2 0 0 2 2 2 0 Spherulation-specific family 4 Glyco_tran_28_C PF04101.16 GAX17370.1 - 0.00084 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Tam41_Mmp37 PF09139.11 GAX17371.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial TMEM151 PF14857.6 GAX17372.1 - 1.3e-07 30.9 0.1 1.9e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 TMEM151 family Proteasome PF00227.26 GAX17373.1 - 1.1e-09 38.1 0.0 1.3e-06 28.0 0.0 2.7 3 0 0 3 3 3 2 Proteasome subunit MNNL PF07657.13 GAX17374.1 - 0.041 13.9 0.7 0.079 13.0 0.7 1.5 1 0 0 1 1 1 0 N terminus of Notch ligand EspG PF06872.11 GAX17374.1 - 0.084 11.4 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 EspG protein Ank_2 PF12796.7 GAX17375.1 - 4.7e-30 104.0 0.8 4e-12 46.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX17375.1 - 9.5e-29 99.4 2.1 1.2e-07 32.1 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17375.1 - 6.5e-26 87.6 2.3 6.2e-05 23.1 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 GAX17375.1 - 3.9e-19 68.5 2.1 1.5e-06 28.4 0.0 3.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX17375.1 - 9.5e-15 54.3 6.7 0.00013 22.2 0.1 5.5 7 0 0 7 7 7 3 Ankyrin repeat Glyoxalase_3 PF13468.6 GAX17376.1 - 8e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain EF-hand_7 PF13499.6 GAX17377.1 - 0.046 14.2 0.0 2.9 8.4 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain pair Ribosomal_L27 PF01016.19 GAX17378.1 - 3.4e-31 107.1 1.9 4.6e-31 106.7 1.9 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein YbfN PF13982.6 GAX17378.1 - 0.037 14.3 0.3 0.06 13.6 0.3 1.3 1 0 0 1 1 1 0 YbfN-like lipoprotein PI31_Prot_N PF11566.8 GAX17379.1 - 3e-05 23.9 0.0 6.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PAPS_reduct PF01507.19 GAX17380.1 - 5.4e-36 124.2 0.1 7.8e-36 123.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 GAX17380.1 - 2.1e-12 46.9 0.0 5.7e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 GAX17380.1 - 0.026 14.4 0.1 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 GAX17380.1 - 0.062 13.7 0.0 0.21 12.0 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain RLL PF10036.9 GAX17380.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein PAPS_reduct PF01507.19 GAX17381.1 - 1.3e-23 83.9 0.2 1.9e-23 83.4 0.2 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.25 GAX17383.1 - 3.1e-34 118.5 0.0 1.6e-32 112.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 GAX17383.1 - 4.1e-33 114.3 0.3 8.6e-33 113.2 0.3 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 GAX17383.1 - 4e-17 62.3 0.0 1.9e-14 53.6 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 GAX17383.1 - 6.7e-05 22.6 1.0 0.00048 19.8 1.2 2.3 2 0 0 2 2 2 1 PQQ-like domain Kdo PF06293.14 GAX17383.1 - 0.002 17.5 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX17383.1 - 0.064 12.0 0.1 0.45 9.2 0.2 2.0 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 GAX17383.1 - 0.068 13.1 0.2 0.21 11.5 0.2 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ PF01011.21 GAX17383.1 - 0.15 12.1 0.1 6.8 6.8 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat Peptidase_C12 PF01088.21 GAX17385.1 - 1.1e-55 188.6 0.0 1.3e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Activator_LAG-3 PF11498.8 GAX17385.1 - 0.018 14.0 1.7 0.024 13.6 1.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Proteasome PF00227.26 GAX17386.1 - 1e-29 103.4 0.4 1.6e-29 102.8 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit POT1 PF02765.17 GAX17387.1 - 1.7e-14 53.9 0.0 4.4e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 GAX17387.1 - 3e-05 24.0 0.0 0.00073 19.4 0.0 2.7 2 1 0 2 2 2 1 ssDNA-binding domain of telomere protection protein Pih1_fungal_CS PF18482.1 GAX17387.1 - 0.052 14.1 0.1 0.17 12.4 0.1 1.9 1 0 0 1 1 1 0 Fungal Pih1 CS domain AOX PF01786.17 GAX17388.1 - 3.9e-74 248.9 0.1 5.6e-74 248.3 0.1 1.2 1 0 0 1 1 1 1 Alternative oxidase EF-hand_5 PF13202.6 GAX17388.1 - 4.7e-05 22.7 0.2 0.0001 21.6 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GAX17388.1 - 0.00023 20.5 0.0 0.00062 19.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAX17388.1 - 0.00059 20.2 0.2 0.0015 19.0 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX17388.1 - 0.00076 19.2 0.1 0.0028 17.5 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 GAX17388.1 - 0.023 14.5 0.1 0.9 9.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Cystatin PF00031.21 GAX17389.1 - 0.00048 20.3 0.4 0.0014 18.8 0.4 1.8 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 GAX17389.1 - 0.0059 16.9 0.1 0.0098 16.2 0.1 1.4 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Methyltrans_SAM PF10672.9 GAX17390.1 - 5.8e-14 51.9 0.0 7.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase MTS PF05175.14 GAX17390.1 - 2.6e-09 36.9 0.1 4.7e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX17390.1 - 5.5e-08 32.7 0.1 1.1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX17390.1 - 1.1e-07 31.7 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 GAX17390.1 - 3.9e-07 29.9 1.1 6.5e-06 25.9 1.1 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 GAX17390.1 - 7e-07 29.9 0.4 2.5e-06 28.1 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX17390.1 - 9.8e-06 25.2 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 GAX17390.1 - 7e-05 22.8 1.5 0.00015 21.7 0.2 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 GAX17390.1 - 9.7e-05 22.5 0.2 0.00015 21.9 0.2 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 GAX17390.1 - 0.00059 19.6 0.0 0.0008 19.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 GAX17390.1 - 0.023 15.4 0.1 0.062 14.0 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAX17390.1 - 0.027 14.3 0.0 0.063 13.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 GAX17390.1 - 0.036 13.2 1.6 0.07 12.3 0.6 2.0 2 1 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Ferrochelatase PF00762.19 GAX17391.1 - 1.1e-110 369.7 0.0 1.4e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 GAX17391.1 - 0.00036 20.8 0.0 0.019 15.3 0.0 2.8 2 0 0 2 2 2 1 CbiX Peptidase_C2 PF00648.21 GAX17392.1 - 2e-59 201.1 0.1 1.3e-58 198.4 0.0 2.2 2 1 0 2 2 2 1 Calpain family cysteine protease zf-GRF PF06839.12 GAX17392.1 - 2.8e-07 30.5 3.1 0.00034 20.7 0.3 2.9 2 0 0 2 2 2 2 GRF zinc finger UBA_4 PF14555.6 GAX17392.1 - 0.00014 21.6 0.1 0.00034 20.4 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain SH3BGR PF04908.15 GAX17392.1 - 0.27 11.4 3.3 0.12 12.6 0.4 1.9 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Ank_2 PF12796.7 GAX17393.1 - 4.2e-08 33.7 0.0 9.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX17393.1 - 4.3e-08 33.5 0.0 2.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX17393.1 - 1.5e-05 25.1 0.0 0.087 13.2 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17393.1 - 3.6e-05 23.8 0.0 0.0011 19.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX17393.1 - 0.067 13.7 0.0 0.31 11.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Aldo_ket_red PF00248.21 GAX17394.1 - 6.2e-36 124.1 0.0 9.3e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TauD PF02668.16 GAX17394.1 - 3.9e-26 92.4 1.5 2.7e-25 89.7 1.5 2.0 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family YdjC PF04794.12 GAX17394.1 - 0.16 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 YdjC-like protein DUF4479 PF14794.6 GAX17394.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Rieske PF00355.26 GAX17395.1 - 0.0065 16.4 0.1 0.0099 15.8 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Dot_icm_IcmQ PF09475.10 GAX17396.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) YIF1 PF03878.15 GAX17397.1 - 2.2e-52 178.0 4.4 3e-52 177.5 4.4 1.1 1 0 0 1 1 1 1 YIF1 LepA_C PF06421.12 GAX17398.1 - 1.2e-36 125.1 2.1 2.5e-36 124.1 2.1 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 GAX17398.1 - 5.1e-33 114.3 0.0 1.2e-32 113.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX17398.1 - 2.3e-11 43.6 0.0 5.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Guanylate_cyc PF00211.20 GAX17399.1 - 8.6e-54 181.9 0.0 1.4e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 GAX17399.1 - 5.8e-51 173.2 0.0 6.1e-49 166.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAX17399.1 - 3.6e-46 157.7 0.0 2.1e-43 148.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain ANF_receptor PF01094.28 GAX17399.1 - 8.2e-23 81.1 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 GAX17399.1 - 9.1e-12 45.3 0.2 1.9e-11 44.2 0.2 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Kdo PF06293.14 GAX17399.1 - 0.00052 19.4 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAX17399.1 - 0.0053 16.4 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Guanylate_cyc PF00211.20 GAX17400.1 - 7.1e-54 182.2 0.1 1.1e-53 181.6 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 GAX17400.1 - 6.2e-50 169.9 0.0 8.9e-48 162.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAX17400.1 - 2.3e-45 155.0 0.0 1.8e-42 145.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain ANF_receptor PF01094.28 GAX17400.1 - 7.3e-25 87.8 0.0 1.6e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 GAX17400.1 - 1.2e-15 58.0 0.6 3.5e-15 56.5 0.5 1.7 2 0 0 2 2 2 1 Periplasmic binding protein Kdo PF06293.14 GAX17400.1 - 0.0014 18.1 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAX17400.1 - 0.015 14.9 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Arfaptin PF06456.13 GAX17400.1 - 0.16 11.5 0.2 0.74 9.3 0.0 2.0 2 0 0 2 2 2 0 Arfaptin-like domain Guanylate_cyc PF00211.20 GAX17401.1 - 4.6e-53 179.6 0.0 7.7e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 GAX17401.1 - 1e-50 172.5 0.0 5.5e-49 166.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GAX17401.1 - 1.1e-44 152.9 0.0 2e-42 145.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain ANF_receptor PF01094.28 GAX17401.1 - 2e-21 76.5 0.0 4.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 GAX17401.1 - 1.1e-11 45.1 0.2 2e-11 44.1 0.2 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Kdo PF06293.14 GAX17401.1 - 0.00038 19.9 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAX17401.1 - 0.027 14.1 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF732 PF05305.14 GAX17401.1 - 0.029 14.7 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF732) APH PF01636.23 GAX17401.1 - 0.07 13.0 0.0 1.4 8.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family HSF_DNA-bind PF00447.17 GAX17402.1 - 0.0039 17.8 0.1 0.0082 16.7 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Aldo_ket_red PF00248.21 GAX17403.1 - 4.1e-42 144.4 0.1 1.3e-39 136.2 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 GAX17404.1 - 1.6e-09 38.2 7.3 0.014 16.2 0.0 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17404.1 - 2.1e-08 34.4 0.8 0.0037 17.5 0.0 4.0 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 GAX17404.1 - 0.0016 18.5 0.5 0.0028 17.7 0.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 GAX17404.1 - 0.013 15.8 2.0 0.025 14.9 2.0 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family HOOK PF05622.12 GAX17404.1 - 0.043 12.0 0.6 0.058 11.5 0.6 1.1 1 0 0 1 1 1 0 HOOK protein 4HBT PF03061.22 GAX17404.1 - 0.11 12.9 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily Shugoshin_N PF07558.11 GAX17404.1 - 0.11 12.3 1.2 0.2 11.6 1.2 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 GAX17404.1 - 0.13 12.1 3.7 0.77 9.6 3.7 2.2 1 1 0 1 1 1 0 Septum formation initiator YabA PF06156.13 GAX17404.1 - 0.21 12.3 0.2 0.38 11.4 0.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 GAX17404.1 - 0.21 11.8 0.8 0.85 9.9 0.7 1.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 GAX17404.1 - 0.33 11.4 2.2 0.55 10.7 2.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 GAX17404.1 - 0.52 10.4 4.3 0.62 10.2 2.9 1.8 1 1 2 3 3 3 0 Basic region leucine zipper CBM_6 PF03422.15 GAX17405.1 - 1.2e-33 116.1 4.1 4.3e-11 43.2 0.3 3.2 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX17405.1 - 4.8e-23 81.4 1.7 1.8e-07 31.3 0.0 3.4 3 1 0 3 3 3 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX17405.1 - 0.00019 21.7 2.7 0.57 10.4 0.3 3.5 3 1 0 3 3 3 2 Carbohydrate binding module (family 35) DUF4761 PF15958.5 GAX17405.1 - 0.032 14.4 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) FMN_dh PF01070.18 GAX17406.1 - 2e-114 382.3 0.0 2.4e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 GAX17406.1 - 1.3e-10 40.9 1.9 1.4e-09 37.4 0.8 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 GAX17406.1 - 2.4e-08 33.5 0.1 0.001 18.3 0.1 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 GAX17406.1 - 4.8e-07 29.2 1.0 4.2e-06 26.1 0.5 2.0 1 1 1 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 GAX17406.1 - 6.7e-06 25.7 2.7 1e-05 25.1 2.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 GAX17406.1 - 3.5e-05 23.2 1.5 0.043 13.1 0.3 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAX17406.1 - 0.0043 16.5 0.1 0.028 13.9 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 GAX17406.1 - 0.024 14.0 0.0 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator TPR_12 PF13424.6 GAX17407.1 - 4.2e-06 27.0 0.1 0.06 13.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17407.1 - 0.00019 21.1 0.2 0.16 11.9 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17407.1 - 0.00086 19.2 0.5 0.65 10.3 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX17407.1 - 0.0093 15.2 0.8 0.024 13.9 0.4 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX17407.1 - 0.01 16.0 1.1 3.6 7.9 0.1 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAX17407.1 - 0.028 14.1 0.1 0.08 12.6 0.1 1.8 1 0 0 1 1 1 0 TPR repeat TPR_7 PF13176.6 GAX17407.1 - 0.05 13.6 0.2 6.7 7.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 GAX17407.1 - 0.066 13.3 1.6 0.13 12.4 0.2 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF2650 PF10853.8 GAX17407.1 - 0.95 9.2 2.5 1.8 8.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) CBM_6 PF03422.15 GAX17408.1 - 1.6e-154 506.6 0.0 2.8e-11 43.8 0.0 14.1 14 0 0 14 14 14 14 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX17408.1 - 1.3e-57 192.8 0.1 2.1e-05 24.6 0.0 14.1 14 0 0 14 14 14 10 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX17408.1 - 2.2e-32 111.9 15.7 0.12 12.6 0.0 14.4 14 0 0 14 14 14 12 Carbohydrate binding module (family 35) DUF5397 PF17375.2 GAX17408.1 - 4e-06 26.4 11.3 0.82 9.4 0.1 9.7 14 0 0 14 14 14 2 Family of unknown function (DUF5397) Iron_transport PF10634.9 GAX17408.1 - 2.2e-05 24.7 0.0 1e+02 3.0 0.0 9.2 13 0 0 13 13 13 0 Fe2+ transport protein MCM PF00493.23 GAX17409.1 - 2.8e-99 330.8 0.0 3.9e-99 330.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX17409.1 - 2.2e-38 131.0 0.9 4.2e-38 130.0 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX17409.1 - 1.4e-25 89.5 1.2 4.1e-25 88.0 1.2 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 GAX17409.1 - 6e-21 74.7 0.1 1.5e-20 73.4 0.1 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 GAX17409.1 - 2.3e-08 34.6 3.1 2.2e-07 31.4 3.2 2.4 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAX17409.1 - 8.5e-07 28.6 0.0 2.6e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX17409.1 - 5.6e-05 23.2 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAX17409.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAX17409.1 - 0.0036 17.2 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HypA PF01155.19 GAX17409.1 - 0.095 12.7 0.1 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_M48_N PF16491.5 GAX17410.1 - 2e-63 213.6 6.1 2e-63 213.6 6.1 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 GAX17410.1 - 6.7e-50 169.6 0.0 1.6e-49 168.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 GAX17410.1 - 0.00033 20.0 0.0 0.00075 18.8 0.0 1.6 1 0 0 1 1 1 1 BlaR1 peptidase M56 5TM-5TMR_LYT PF07694.12 GAX17410.1 - 0.011 15.3 0.1 0.03 13.8 0.1 1.8 1 0 0 1 1 1 0 5TMR of 5TMR-LYT ING PF12998.7 GAX17410.1 - 0.12 13.0 0.2 0.23 12.1 0.2 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding PPR_2 PF13041.6 GAX17411.1 - 0.00082 19.5 0.1 1.9 8.8 0.0 4.4 4 2 0 4 4 4 1 PPR repeat family XPG_I_2 PF12813.7 GAX17411.1 - 0.019 14.4 4.1 0.19 11.2 0.3 2.3 2 0 0 2 2 2 0 XPG domain containing TPR_14 PF13428.6 GAX17411.1 - 0.023 15.5 4.8 2 9.5 0.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 GAX17411.1 - 0.038 14.2 2.3 6.1 7.3 0.0 4.7 3 1 0 3 3 3 0 PPR repeat DnaJ PF00226.31 GAX17412.1 - 4.6e-06 26.6 0.0 2e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 DnaJ domain RPA_interact_N PF14766.6 GAX17412.1 - 0.098 12.3 1.2 6.5 6.5 0.1 2.8 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Pkinase PF00069.25 GAX17413.1 - 6.7e-36 124.0 0.0 6.1e-35 120.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17413.1 - 2.7e-14 53.1 0.1 4.9e-09 35.9 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.23 GAX17413.1 - 1.3e-06 28.6 0.3 2.9e-06 27.4 0.3 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX17413.1 - 0.0022 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAX17413.1 - 0.0097 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX17413.1 - 0.028 13.7 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 GAX17413.1 - 0.034 12.9 0.1 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase SR-25 PF10500.9 GAX17413.1 - 0.17 11.4 3.1 0.26 10.9 3.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA-synt_1b PF00579.25 GAX17414.1 - 2.9e-49 168.0 0.0 2.4e-43 148.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) RRM_1 PF00076.22 GAX17415.1 - 5.1e-14 51.9 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RTC PF01137.21 GAX17417.1 - 2.8e-38 131.4 0.0 3.5e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 GAX17417.1 - 2.5e-26 92.2 0.1 3.7e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SNF2_N PF00176.23 GAX17418.1 - 3.1e-44 151.1 0.1 5.6e-44 150.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CW PF07496.15 GAX17418.1 - 4.5e-14 52.2 7.0 2.1e-13 50.1 7.0 2.3 1 0 0 1 1 1 1 CW-type Zinc Finger Helicase_C PF00271.31 GAX17418.1 - 1e-12 48.4 0.0 4.2e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX17418.1 - 5.8e-06 26.2 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAX17418.1 - 7.6e-05 22.8 1.5 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDP-OH_P_transf PF01066.21 GAX17419.1 - 3.7e-13 50.0 2.4 3.7e-13 50.0 2.4 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2569 PF10754.9 GAX17419.1 - 0.063 13.7 0.4 0.063 13.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) AAA PF00004.29 GAX17420.1 - 1.1e-38 132.6 0.0 2.1e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX17420.1 - 2.1e-13 49.9 0.1 4e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX17420.1 - 2.1e-05 25.0 0.0 0.024 15.0 0.1 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAX17420.1 - 0.00033 20.6 0.0 0.0014 18.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX17420.1 - 0.0014 18.9 0.2 0.11 12.7 0.1 2.7 2 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 GAX17420.1 - 0.003 17.3 0.0 0.0087 15.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GAX17420.1 - 0.0062 15.9 0.3 0.015 14.7 0.2 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI FtsH_ext PF06480.15 GAX17420.1 - 0.0063 16.9 0.0 0.018 15.4 0.0 1.9 1 1 0 1 1 1 1 FtsH Extracellular IstB_IS21 PF01695.17 GAX17420.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 GAX17420.1 - 0.048 13.6 0.1 0.26 11.2 0.1 2.3 2 1 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 GAX17420.1 - 0.052 13.6 0.0 7.1 6.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX17420.1 - 0.071 13.3 0.1 0.21 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAX17420.1 - 0.11 11.6 0.0 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 GAX17420.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 GAX17420.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GAX17420.1 - 0.21 12.1 0.0 0.57 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain WW PF00397.26 GAX17421.1 - 0.00063 19.8 0.5 0.0011 19.0 0.5 1.4 1 0 0 1 1 1 1 WW domain AAA_11 PF13086.6 GAX17422.1 - 1.9e-68 231.1 1.6 3.6e-68 230.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 GAX17422.1 - 1.6e-57 194.4 0.0 2.8e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX17422.1 - 4.7e-09 36.2 0.5 0.00075 19.3 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAX17422.1 - 9.8e-08 32.5 0.2 2.4e-06 28.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAX17422.1 - 4e-06 26.7 0.2 0.76 9.5 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAX17422.1 - 8.2e-06 26.1 0.2 0.00039 20.7 0.0 3.2 3 1 0 3 3 3 1 AAA domain WW PF00397.26 GAX17422.1 - 5.8e-05 23.1 0.1 0.00013 22.0 0.1 1.6 1 0 0 1 1 1 1 WW domain AAA PF00004.29 GAX17422.1 - 0.00052 20.4 0.1 0.0026 18.2 0.0 2.3 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX17422.1 - 0.005 17.2 0.9 0.019 15.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain ResIII PF04851.15 GAX17422.1 - 0.0054 16.8 0.1 0.69 9.9 0.1 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAX17422.1 - 0.008 15.7 0.8 1.3 8.5 0.1 3.1 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 GAX17422.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 GAX17422.1 - 0.013 14.8 0.1 0.42 9.8 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_27 PF13514.6 GAX17422.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAX17422.1 - 0.062 13.2 0.0 0.75 9.7 0.0 2.4 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 GAX17422.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 GAX17422.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 GAX17423.1 - 5.2e-31 107.8 0.0 7.9e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX17423.1 - 3.8e-23 82.4 0.0 5.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX17423.1 - 5.7e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX17423.1 - 0.03 14.9 0.1 0.14 12.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAX17423.1 - 0.038 14.3 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 GAX17423.1 - 0.044 13.4 0.1 0.19 11.4 0.1 2.1 2 1 0 2 2 2 0 Thymidylate kinase Peptidase_M11 PF05548.11 GAX17427.1 - 6.9e-12 45.1 1.5 1.4e-10 40.8 1.6 2.1 1 1 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_5 PF13688.6 GAX17427.1 - 0.0021 18.3 0.3 0.0039 17.4 0.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Metallopep PF12044.8 GAX17427.1 - 0.0047 15.6 0.3 0.0094 14.6 0.3 1.4 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M10 PF00413.24 GAX17427.1 - 0.0053 16.6 0.5 0.0092 15.8 0.5 1.5 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 GAX17427.1 - 0.0071 16.9 0.1 0.072 13.6 0.0 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 GAX17427.1 - 0.011 15.7 0.1 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M54 DUF4953 PF16313.5 GAX17427.1 - 0.014 14.6 0.4 0.024 13.9 0.4 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 GAX17427.1 - 0.015 15.0 0.1 0.037 13.7 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 GAX17427.1 - 0.059 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF1463 PF07316.11 GAX17427.1 - 0.068 13.0 0.6 0.13 12.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1463) MMR_HSR1 PF01926.23 GAX17429.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase YchF-GTPase_C PF06071.13 GAX17429.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF933) DUF819 PF05684.12 GAX17430.1 - 1.9e-36 125.9 21.8 4.7e-36 124.6 21.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF819) DUF4505 PF14956.6 GAX17431.1 - 8.2e-27 94.1 0.0 1.4e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) AMP-binding PF00501.28 GAX17432.1 - 4e-95 318.9 0.0 5.4e-95 318.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UTP25 PF06862.12 GAX17433.1 - 4.1e-138 461.1 0.1 6.2e-138 460.5 0.1 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 BTB PF00651.31 GAX17434.1 - 4.4e-14 52.7 0.4 7.8e-13 48.6 0.2 2.8 2 1 0 2 2 2 1 BTB/POZ domain HTH_Tnp_ISL3 PF13542.6 GAX17434.1 - 0.033 13.6 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 PseudoU_synth_2 PF00849.22 GAX17435.1 - 1.8e-13 50.9 0.2 7.7e-13 48.8 0.2 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 GAX17435.1 - 6.4e-05 22.6 0.1 0.00015 21.4 0.1 1.7 1 0 0 1 1 1 1 S4 domain DUF1062 PF06353.12 GAX17435.1 - 0.11 13.4 0.0 0.33 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) Adipogenin PF15202.6 GAX17436.1 - 0.086 12.9 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Adipogenin pEK499_p136 PF18736.1 GAX17437.1 - 0.015 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 HEPN pEK499 p136 PCNA_N PF00705.18 GAX17437.1 - 1.1 8.9 4.3 0.6 9.8 0.3 2.3 3 0 0 3 3 3 0 Proliferating cell nuclear antigen, N-terminal domain Ribosomal_L5_C PF00673.21 GAX17438.1 - 4.8e-22 78.0 0.1 1.1e-21 76.7 0.1 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAX17438.1 - 1.1e-21 76.9 0.0 4.8e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 GAX17438.1 - 0.05 13.3 0.8 0.091 12.5 0.2 1.7 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Fez1 PF06818.15 GAX17440.1 - 0.11 13.0 0.3 0.11 13.0 0.3 4.5 1 1 3 4 4 4 0 Fez1 CCDC144C PF14915.6 GAX17440.1 - 5.6 6.0 99.7 3.1 6.8 0.1 4.2 1 1 3 4 4 4 0 CCDC144C protein coiled-coil region PPR_2 PF13041.6 GAX17441.1 - 7.6e-23 80.4 2.7 2.8e-07 30.6 0.0 6.3 4 2 2 6 6 6 4 PPR repeat family PPR_3 PF13812.6 GAX17441.1 - 1.2e-21 76.5 0.5 5e-05 23.3 0.0 4.9 5 0 0 5 5 5 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX17441.1 - 2.8e-17 62.1 0.0 0.014 15.1 0.0 8.0 8 1 1 9 9 9 4 PPR repeat PPR_long PF17177.4 GAX17441.1 - 3.9e-07 29.7 9.3 5.3e-05 22.7 3.8 3.0 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX17441.1 - 3.7e-06 26.8 14.3 3.9 7.9 0.0 8.2 10 0 0 10 10 10 4 PPR repeat Vps54_N PF10475.9 GAX17441.1 - 0.0028 17.0 0.6 1.2 8.4 0.0 3.2 1 1 1 3 3 3 2 Vacuolar-sorting protein 54, of GARP complex HIG_1_N PF04588.13 GAX17442.1 - 0.00012 22.3 0.1 0.00065 19.9 0.0 2.2 2 1 0 2 2 2 1 Hypoxia induced protein conserved region HMGL-like PF00682.19 GAX17443.1 - 1.3e-49 169.1 0.2 2.8e-49 168.1 0.2 1.6 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 GAX17443.1 - 4.6e-21 75.1 0.8 1.3e-19 70.4 0.1 2.8 3 0 0 3 3 3 1 LeuA allosteric (dimerisation) domain Usp PF00582.26 GAX17443.1 - 0.025 15.1 0.0 16 6.0 0.0 3.3 2 1 0 2 2 2 0 Universal stress protein family LRR_6 PF13516.6 GAX17444.1 - 2.1e-08 33.6 9.9 0.11 12.6 0.2 5.6 5 0 0 5 5 5 3 Leucine Rich repeat NACHT PF05729.12 GAX17444.1 - 1e-07 32.0 0.1 2.5e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 NACHT domain CHAT PF12770.7 GAX17444.1 - 1.1e-07 31.6 1.4 1.2e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 CHAT domain AAA_16 PF13191.6 GAX17444.1 - 2.3e-06 28.1 0.3 2e-05 25.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX17444.1 - 0.00024 21.4 0.1 0.0008 19.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain Arm PF00514.23 GAX17444.1 - 0.00063 19.7 0.0 7.5 6.7 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat LRR_1 PF00560.33 GAX17444.1 - 0.11 13.1 11.5 73 4.5 0.3 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat NB-ARC PF00931.22 GAX17444.1 - 0.13 11.5 1.6 0.17 11.1 0.3 1.8 2 0 0 2 2 2 0 NB-ARC domain LRR_4 PF12799.7 GAX17444.1 - 0.15 12.5 16.6 0.57 10.7 1.1 4.6 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) Methyltransf_5 PF01795.19 GAX17445.1 - 5.1e-77 259.4 0.0 6.9e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Pkinase PF00069.25 GAX17446.1 - 8.9e-07 28.5 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX17446.1 - 0.0025 16.7 0.0 0.0036 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 GAX17446.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 FHA domain OTCace_N PF02729.21 GAX17447.1 - 1.2e-41 142.2 0.0 3e-41 140.9 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 GAX17447.1 - 7.7e-33 113.8 0.0 1.7e-32 112.7 0.0 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 2OG-FeII_Oxy PF03171.20 GAX17448.1 - 1.1e-08 35.5 0.0 4.1e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF987 PF06174.11 GAX17448.1 - 0.3 11.0 1.7 3.9 7.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF987) Ank_2 PF12796.7 GAX17450.1 - 1.5e-39 134.5 0.0 2.4e-07 31.2 0.0 5.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX17450.1 - 9.3e-30 102.3 0.0 2.3e-06 27.7 0.0 7.1 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX17450.1 - 3.3e-21 75.4 0.4 0.0039 17.7 0.0 7.0 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17450.1 - 6.1e-19 66.1 0.8 0.43 11.3 0.0 9.5 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 GAX17450.1 - 2.7e-17 62.3 0.0 0.28 11.7 0.0 8.6 9 0 0 9 9 9 4 Ankyrin repeat DUF5492 PF17596.2 GAX17450.1 - 0.002 18.4 0.3 1.5 9.2 0.0 3.7 4 0 0 4 4 4 1 Family of unknown function (DUF5492) SUI1 PF01253.22 GAX17450.1 - 0.012 16.1 0.1 1.3 9.7 0.0 3.0 2 1 1 3 3 3 0 Translation initiation factor SUI1 EST1_DNA_bind PF10373.9 GAX17451.1 - 0.033 13.7 0.6 0.045 13.2 0.2 1.4 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain Epimerase PF01370.21 GAX17452.1 - 0.0023 17.5 0.0 0.039 13.4 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 GAX17452.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PhyH PF05721.13 GAX17453.1 - 1.2e-08 35.5 0.1 3.7e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 GAX17453.1 - 0.00034 20.5 0.0 0.045 13.5 0.0 2.4 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family DUF4462 PF14692.6 GAX17453.1 - 0.014 14.9 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Aminotran_4 PF01063.19 GAX17454.1 - 2.8e-28 99.3 0.0 3.3e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV MFS_5 PF05631.14 GAX17455.1 - 2.1e-64 217.7 4.3 2.1e-64 217.7 4.3 1.5 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAX17455.1 - 6.6e-19 68.0 27.8 6.6e-19 68.0 27.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Mito_carr PF00153.27 GAX17456.1 - 1.2e-57 191.9 2.9 4.1e-21 74.7 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 GAX17456.1 - 2.1 8.7 8.2 47 4.4 8.4 2.5 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Methyltransf_12 PF08242.12 GAX17457.1 - 5.2e-09 36.8 0.0 1.2e-08 35.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX17457.1 - 2.1e-08 34.1 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX17457.1 - 9.9e-08 32.6 0.0 3.3e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX17457.1 - 1.2e-06 29.1 0.0 2.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX17457.1 - 2.3e-06 27.5 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4030 PF13222.6 GAX17457.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4030) zinc-ribbons_6 PF07191.12 GAX17457.1 - 0.17 11.9 5.4 0.16 12.0 1.7 2.2 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_9 PF14369.6 GAX17457.1 - 0.21 11.9 2.4 1.3 9.4 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon TPR_12 PF13424.6 GAX17458.1 - 0.0014 18.9 0.8 0.014 15.6 0.0 2.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17458.1 - 0.031 14.1 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SAP PF02037.27 GAX17459.1 - 2.8e-12 46.1 0.2 1.2e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 SAP domain NYN PF01936.18 GAX17459.1 - 3e-10 40.8 0.0 6.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 NYN domain DnaT PF17948.1 GAX17459.1 - 0.12 12.1 0.1 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 DnaT DNA-binding domain TauD PF02668.16 GAX17461.1 - 1.1e-28 100.9 0.0 1.7e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 3HCDH_N PF02737.18 GAX17462.1 - 3.8e-62 209.4 0.2 5.1e-62 209.0 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAX17462.1 - 2.9e-30 104.7 0.0 3.7e-29 101.2 0.0 2.3 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAX17462.1 - 0.0018 18.4 1.7 0.0056 16.9 1.7 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAX17462.1 - 0.0086 16.6 1.1 0.018 15.6 1.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAX17462.1 - 0.039 13.3 1.4 0.12 11.8 1.4 1.8 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNARE PF05739.19 GAX17463.1 - 8.1e-05 22.5 0.2 0.0003 20.7 0.2 2.0 1 0 0 1 1 1 1 SNARE domain UPF0262 PF06793.12 GAX17463.1 - 0.0019 18.3 0.7 0.0019 18.3 0.7 1.8 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0262) DUF2924 PF11149.8 GAX17463.1 - 0.018 15.5 3.1 0.018 15.5 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) Lant_dehydr_C PF14028.6 GAX17463.1 - 0.068 12.7 7.9 0.024 14.2 2.9 1.9 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Cas_DxTHG PF09455.10 GAX17463.1 - 0.14 11.7 8.4 0.19 11.3 8.4 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family PMC2NT PF08066.12 GAX17463.1 - 0.31 11.8 4.3 0.35 11.6 0.3 2.7 1 1 0 2 2 2 0 PMC2NT (NUC016) domain PilJ PF13675.6 GAX17463.1 - 0.51 10.4 15.9 0.53 10.3 6.4 3.0 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Allexi_40kDa PF05549.11 GAX17463.1 - 0.55 9.7 17.0 0.092 12.2 5.8 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Muted PF14942.6 GAX17463.1 - 0.58 10.5 28.4 0.43 10.9 15.6 3.1 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.12 GAX17463.1 - 1.6 8.8 19.1 2.5 8.2 2.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ISG65-75 PF11727.8 GAX17463.1 - 1.9 7.6 16.7 0.11 11.7 3.8 2.7 1 1 2 3 3 3 0 Invariant surface glycoprotein Vac_Fusion PF02346.16 GAX17463.1 - 2.1 8.0 8.0 5.3 6.7 0.1 3.5 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 AIP3 PF03915.13 GAX17463.1 - 4.7 6.2 24.7 2.5 7.1 15.7 2.0 1 1 1 2 2 2 0 Actin interacting protein 3 DUF948 PF06103.11 GAX17463.1 - 5.3 7.4 15.3 9.6 6.5 0.6 3.7 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Plasmid_RAQPRD PF09686.10 GAX17463.1 - 7.2 6.9 17.6 0.38 11.0 6.6 3.4 1 1 2 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) RE_TdeIII PF09520.10 GAX17463.1 - 10 5.7 15.0 0.059 13.0 3.2 2.3 1 1 1 2 2 2 0 Type II restriction endonuclease, TdeIII L51_S25_CI-B8 PF05047.16 GAX17464.1 - 0.00024 20.9 0.1 0.00041 20.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Molybdop_Fe4S4 PF04879.16 GAX17464.1 - 0.091 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain ADK PF00406.22 GAX17465.1 - 8.1e-35 120.2 0.0 1.5e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX17465.1 - 2.4e-20 73.4 0.0 3.8e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX17465.1 - 7.6e-09 36.2 0.0 1.6e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX17465.1 - 6.5e-07 29.6 0.0 2.4e-06 27.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain EF-hand_8 PF13833.6 GAX17465.1 - 4.2e-06 26.5 0.3 1.8e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX17465.1 - 4.5e-06 25.8 0.2 1.2e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAX17465.1 - 9e-06 26.1 0.3 2.4e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX17465.1 - 1.5e-05 24.5 0.1 0.0022 17.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GAX17465.1 - 0.00013 21.3 0.3 0.00031 20.1 0.3 1.6 1 0 0 1 1 1 1 EF hand Zeta_toxin PF06414.12 GAX17465.1 - 0.0057 16.0 0.0 0.031 13.5 0.0 2.2 3 0 0 3 3 3 1 Zeta toxin dNK PF01712.19 GAX17465.1 - 0.013 15.3 0.1 0.75 9.6 0.0 2.2 1 1 1 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 GAX17465.1 - 0.015 15.6 0.0 0.091 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAX17465.1 - 0.029 14.1 0.0 1.5 8.5 0.0 2.2 1 1 1 2 2 2 0 Thymidylate kinase DUF2075 PF09848.9 GAX17465.1 - 0.043 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 GAX17465.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAX17465.1 - 0.061 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavi_NS5 PF00972.20 GAX17465.1 - 0.063 11.4 0.1 0.087 10.9 0.1 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Ploopntkinase3 PF18751.1 GAX17465.1 - 0.083 12.8 0.1 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 FKBP_C PF00254.28 GAX17466.1 - 5.1e-30 103.6 0.0 1e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glycos_transf_2 PF00535.26 GAX17466.1 - 1.9e-12 47.3 0.0 3.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX17466.1 - 0.00022 21.2 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GAX17466.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 RNA_polI_A34 PF08208.11 GAX17467.1 - 2.7e-15 57.0 21.4 5e-15 56.2 21.4 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 ADK PF00406.22 GAX17468.1 - 1.1e-17 64.5 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX17468.1 - 2.1e-09 37.9 0.0 4.2e-09 36.9 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX17468.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 GAX17468.1 - 0.04 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase SapB_1 PF05184.15 GAX17468.1 - 0.17 12.0 0.8 3.7 7.7 0.2 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 PRP3 PF08572.10 GAX17470.1 - 1.7e-46 158.8 9.9 2.6e-46 158.1 9.1 1.8 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 GAX17470.1 - 1.2e-44 152.0 1.4 3.3e-44 150.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) IF3_C PF00707.22 GAX17471.1 - 3e-30 104.0 0.7 7.1e-30 102.8 0.7 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 GAX17471.1 - 1.2e-23 83.2 0.2 2.9e-23 81.9 0.2 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain CAF1 PF04857.20 GAX17471.1 - 0.26 10.4 3.1 0.4 9.8 3.1 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease NOA36 PF06524.12 GAX17471.1 - 0.35 10.1 13.3 0.64 9.3 13.3 1.4 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 GAX17471.1 - 5.3 7.8 19.5 1.7 9.4 14.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Hat1_N PF10394.9 GAX17473.1 - 9.1e-06 26.0 0.2 0.021 15.0 0.0 3.2 4 0 0 4 4 4 2 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 GAX17473.1 - 0.0036 17.5 0.0 0.008 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 GAX17473.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family Haem_bd PF14376.6 GAX17473.1 - 0.12 12.3 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Haem-binding domain DUF87 PF01935.17 GAX17473.1 - 2 8.5 4.4 7.4 6.6 0.4 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain 5_nucleotid_C PF02872.18 GAX17474.1 - 6.2e-37 127.2 0.0 1.3e-36 126.2 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain TRAM_LAG1_CLN8 PF03798.16 GAX17474.1 - 1.3e-15 57.7 14.3 2.4e-15 56.8 14.3 1.4 1 0 0 1 1 1 1 TLC domain Metallophos PF00149.28 GAX17474.1 - 2.9e-05 24.6 0.0 4.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2358 PF10184.9 GAX17475.1 - 0.0045 17.2 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 GAX17475.1 - 0.16 12.7 0.0 0.26 12.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain NOA36 PF06524.12 GAX17477.1 - 3 7.1 10.6 3.5 6.9 10.6 1.0 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 GAX17477.1 - 3.1 8.1 7.8 4.2 7.6 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sm_multidrug_ex PF06695.11 GAX17478.1 - 7.5e-31 107.3 5.5 1.5e-30 106.3 5.5 1.5 1 0 0 1 1 1 1 Putative small multi-drug export protein NAD_binding_1 PF00175.21 GAX17478.1 - 1.2e-25 90.2 0.0 2.5e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX17478.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain zf-RING_2 PF13639.6 GAX17479.1 - 1.1e-08 35.3 1.7 1.1e-08 35.3 1.7 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GAX17479.1 - 2.6e-08 33.5 2.4 2.6e-08 33.5 2.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX17479.1 - 1.3e-05 24.9 0.3 1.3e-05 24.9 0.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX17479.1 - 2e-05 24.3 0.4 2e-05 24.3 0.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX17479.1 - 4.4e-05 23.6 1.1 4.4e-05 23.6 1.1 1.9 2 0 0 2 2 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 GAX17479.1 - 6.6e-05 22.9 0.4 6.6e-05 22.9 0.4 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAX17479.1 - 0.00053 20.2 4.5 0.00053 20.2 4.5 3.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAX17479.1 - 0.0018 18.3 0.9 0.0018 18.3 0.9 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX17479.1 - 0.011 15.3 1.1 0.011 15.3 1.1 2.4 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAX17479.1 - 0.014 15.3 0.6 0.014 15.3 0.6 2.6 3 0 0 3 3 3 0 zinc-RING finger domain RINGv PF12906.7 GAX17479.1 - 2.3 8.4 9.2 0.13 12.4 2.4 2.2 2 0 0 2 2 2 0 RING-variant domain Ctr PF04145.15 GAX17480.1 - 0.0075 16.9 3.1 0.058 14.0 3.4 2.4 1 1 1 2 2 2 1 Ctr copper transporter family DHHC PF01529.20 GAX17480.1 - 0.014 15.5 0.3 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase AI-2E_transport PF01594.16 GAX17480.1 - 0.017 14.3 3.7 0.54 9.4 0.3 2.2 2 0 0 2 2 2 0 AI-2E family transporter DUF4199 PF13858.6 GAX17480.1 - 0.024 15.0 0.9 0.024 15.0 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) FA_desaturase PF00487.24 GAX17480.1 - 8.8 6.1 8.0 1.5 8.6 0.2 2.7 2 1 0 2 2 2 0 Fatty acid desaturase Pyrid_oxidase_2 PF13883.6 GAX17481.1 - 1.3e-26 93.6 0.0 2.8e-26 92.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 GAX17481.1 - 5.5e-13 49.3 0.0 1.5e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 GAX17481.1 - 0.0027 17.9 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Ctr PF04145.15 GAX17482.1 - 1.1e-11 45.5 17.4 7e-07 30.0 8.5 2.6 1 1 2 3 3 3 2 Ctr copper transporter family PalH PF08733.10 GAX17482.1 - 0.37 9.8 4.1 0.54 9.2 4.1 1.3 1 1 0 1 1 1 0 PalH/RIM21 LCM PF04072.14 GAX17483.1 - 1.8e-10 41.0 0.0 3.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF5042 PF16445.5 GAX17483.1 - 0.17 10.2 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) Mt_ATP-synt_D PF05873.12 GAX17484.1 - 4.4e-11 42.9 5.3 5.4e-11 42.6 5.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Trp_Tyr_perm PF03222.13 GAX17485.1 - 6.7e-37 127.5 16.6 3.7e-25 88.8 12.3 2.1 1 1 1 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 GAX17485.1 - 0.23 10.1 13.9 1.3 7.7 13.9 2.2 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein SAP PF02037.27 GAX17486.1 - 5.8e-11 41.9 0.2 1.7e-10 40.4 0.2 1.9 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 GAX17486.1 - 0.074 12.7 0.3 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 Telomere stability C-terminal CDI PF02234.19 GAX17486.1 - 0.42 10.8 6.1 0.37 11.0 0.2 3.7 4 0 0 4 4 4 0 Cyclin-dependent kinase inhibitor HeH PF12949.7 GAX17486.1 - 2.7 7.8 5.3 0.41 10.4 0.2 2.3 3 0 0 3 3 3 0 HeH/LEM domain LRR_8 PF13855.6 GAX17487.1 - 5.4e-09 35.7 12.3 6.5e-08 32.2 4.5 2.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAX17487.1 - 0.0007 19.9 13.5 0.014 15.8 0.7 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAX17487.1 - 0.019 14.5 2.5 0.03 13.8 2.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Glyco_tranf_2_4 PF13704.6 GAX17488.1 - 3.5e-05 24.2 1.2 7.8e-05 23.1 1.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Citrate_bind PF16114.5 GAX17489.1 - 9.7e-87 289.0 0.0 2e-86 288.1 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 GAX17489.1 - 5.2e-24 85.0 0.1 1.1e-21 77.3 0.1 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 GAX17489.1 - 4.9e-15 55.7 0.0 1.2e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 GAX17489.1 - 7.9e-11 42.5 0.0 1.8e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 GAX17489.1 - 5.1e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 GAX17489.1 - 0.032 14.0 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain NTP_transf_3 PF12804.7 GAX17489.1 - 0.094 13.1 0.2 0.28 11.5 0.0 1.9 3 0 0 3 3 3 0 MobA-like NTP transferase domain DJ-1_PfpI PF01965.24 GAX17490.1 - 3.2e-14 53.1 0.1 1.4e-13 50.9 0.1 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAX17490.1 - 5.9e-10 39.2 0.0 6e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 GAX17492.1 - 5e-16 58.9 0.1 2e-15 57.0 0.1 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAX17492.1 - 8.5e-11 41.9 0.0 1e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like RACo_C_ter PF14574.6 GAX17492.1 - 0.1 11.6 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain Bac_DNA_binding PF00216.21 GAX17495.1 - 1.6e-22 79.5 0.6 2.2e-22 79.1 0.3 1.4 1 1 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 GAX17495.1 - 2.9e-07 30.6 0.2 3.6e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif DUF3294 PF07957.11 GAX17495.1 - 0.073 12.8 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) SHS2_FTSA PF02491.20 GAX17495.1 - 0.11 12.9 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA HU-CCDC81_bac_2 PF18175.1 GAX17495.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 TIC20 PF16166.5 GAX17496.1 - 0.064 13.0 3.6 0.11 12.3 3.6 1.3 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like DUF996 PF06195.13 GAX17496.1 - 0.16 12.3 1.9 0.36 11.1 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF996) CREPT PF16566.5 GAX17496.1 - 3.4 7.8 10.9 1.3 9.2 2.3 2.7 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Peptidase_M24 PF00557.24 GAX17497.1 - 1.2e-44 152.5 0.0 3.9e-44 150.8 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 GAX17497.1 - 2.9e-44 151.0 0.4 5.2e-42 143.7 0.1 3.1 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 GAX17497.1 - 2.8e-24 85.0 0.4 1e-23 83.2 0.4 2.1 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAX17497.1 - 7.7e-20 71.9 0.1 3.6e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Acetyltransf_1 PF00583.25 GAX17499.1 - 1.1e-11 45.0 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX17499.1 - 8.5e-10 38.6 0.1 1.2e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX17499.1 - 9.8e-09 35.5 0.2 1.6e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX17499.1 - 8.7e-07 28.8 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAX17499.1 - 4.9e-05 23.5 0.1 7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX17499.1 - 0.00071 19.6 0.1 0.0012 19.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAX17499.1 - 0.046 13.2 0.9 0.083 12.4 0.9 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase MtrH PF02007.18 GAX17500.1 - 0.013 14.6 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit DUF2972 PF11186.8 GAX17500.1 - 0.015 15.3 0.1 0.017 15.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) TPR_12 PF13424.6 GAX17501.1 - 5.8e-14 52.1 0.0 1.4e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17501.1 - 2.8e-11 42.9 0.1 0.034 14.0 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17501.1 - 3.8e-08 32.8 1.1 0.47 10.7 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17501.1 - 1.1e-05 25.0 1.0 1.3 9.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX17501.1 - 0.00016 21.1 0.1 0.0003 20.3 0.1 1.3 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 GAX17501.1 - 0.0021 18.1 0.9 30 5.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX17501.1 - 0.012 15.7 0.0 2.1 8.5 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17501.1 - 0.018 15.8 1.4 15 6.7 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17501.1 - 0.026 14.5 0.3 1.7 8.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-Nse PF11789.8 GAX17501.1 - 0.035 13.9 0.2 0.11 12.3 0.2 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit His_Phos_1 PF00300.22 GAX17503.1 - 1e-17 64.5 0.0 3.2e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 GAX17503.1 - 9.3e-05 21.9 0.0 0.0057 16.0 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) IBN_N PF03810.19 GAX17504.1 - 3.1e-12 46.2 1.6 6.4e-11 42.0 0.2 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 GAX17504.1 - 2.4e-08 33.2 0.0 6.7e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 GAX17504.1 - 0.0036 17.4 0.4 0.16 12.0 0.1 2.9 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 GAX17504.1 - 0.0064 16.9 3.9 2.7 8.4 0.4 4.3 5 1 0 5 5 5 2 HEAT repeats TAF6_C PF07571.13 GAX17504.1 - 0.034 14.5 0.2 8.5 6.8 0.1 4.3 4 1 1 5 5 5 0 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 GAX17504.1 - 0.4 11.3 8.4 3.7 8.2 0.0 5.5 5 1 1 6 6 6 0 HEAT-like repeat Pentapeptide_4 PF13599.6 GAX17506.1 - 4.8e-12 45.9 3.3 1.4e-07 31.6 0.4 1.8 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 GAX17506.1 - 5.8e-11 41.8 8.6 3e-06 26.8 3.3 3.0 1 1 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 GAX17506.1 - 4.5e-07 29.9 2.6 0.00012 22.1 1.6 2.8 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) p450 PF00067.22 GAX17507.1 - 4.3e-75 253.2 0.0 5.9e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TSP_3 PF02412.18 GAX17508.1 - 1.1e-09 37.8 374.6 0.0055 16.4 6.9 25.6 24 2 1 25 25 25 22 Thrombospondin type 3 repeat Tam41_Mmp37 PF09139.11 GAX17509.1 - 1.7e-70 238.1 0.2 1.4e-61 208.7 0.0 2.0 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial CRAL_TRIO PF00650.20 GAX17510.1 - 2.3e-05 24.2 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain H_PPase PF03030.16 GAX17512.1 - 6.7e-258 857.7 31.1 6.7e-258 857.7 31.1 1.7 2 0 0 2 2 2 1 Inorganic H+ pyrophosphatase KbaA PF14089.6 GAX17512.1 - 0.048 13.5 0.1 0.17 11.7 0.1 2.0 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation DNA_pol_phi PF04931.13 GAX17513.1 - 4.8 5.2 19.4 10 4.1 19.4 1.5 1 0 0 1 1 1 0 DNA polymerase phi PEPCK_ATP PF01293.20 GAX17515.1 - 1.1e-209 696.9 0.0 1.4e-209 696.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 GAX17515.1 - 0.094 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX17515.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain His_Phos_1 PF00300.22 GAX17516.1 - 3e-28 98.9 3.1 7.1e-18 65.0 0.0 4.7 3 1 2 5 5 5 3 Histidine phosphatase superfamily (branch 1) MAF_flag10 PF01973.18 GAX17516.1 - 0.026 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 Pyr_redox_2 PF07992.14 GAX17517.1 - 7e-55 186.3 2.0 9.6e-55 185.9 2.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX17517.1 - 3.7e-32 110.8 2.6 4.8e-32 110.5 0.8 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX17517.1 - 2.3e-17 63.3 5.8 2e-15 57.1 1.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX17517.1 - 1.7e-13 50.6 1.8 3e-13 49.7 1.8 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAX17517.1 - 4.6e-05 22.7 0.1 7.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 GAX17517.1 - 0.0013 18.2 0.1 0.002 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX17517.1 - 0.0021 17.2 2.9 0.03 13.4 1.8 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAX17517.1 - 0.014 14.1 1.8 0.94 8.1 0.4 2.9 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 GAX17517.1 - 0.081 12.0 4.0 0.056 12.5 0.5 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GAX17517.1 - 0.1 12.9 0.8 0.25 11.6 0.8 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 GAX17517.1 - 0.24 10.7 3.3 10 5.4 0.2 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX17517.1 - 0.58 9.7 6.4 0.15 11.6 0.4 2.7 3 1 0 3 3 3 0 FAD dependent oxidoreductase His_Phos_1 PF00300.22 GAX17518.1 - 4.4e-22 78.7 0.0 8.5e-20 71.3 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pro_isomerase PF00160.21 GAX17519.1 - 6.5e-20 72.0 0.0 1.2e-19 71.2 0.0 1.4 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4231 PF14015.6 GAX17519.1 - 0.065 13.7 0.1 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF92 PF01940.16 GAX17520.1 - 2.1e-52 177.9 9.2 3e-52 177.4 9.2 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 RTX PF02382.15 GAX17520.1 - 0.42 10.2 3.6 0.58 9.8 3.6 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein ATG22 PF11700.8 GAX17521.1 - 1.6e-19 70.0 25.3 1.4e-15 56.9 12.9 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAX17521.1 - 3.5e-12 45.9 22.9 4.9e-12 45.4 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2198 PF09964.9 GAX17521.1 - 1.4 9.0 8.3 0.29 11.2 3.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) SPOUT_MTase PF02590.17 GAX17522.1 - 1.1e-29 103.5 0.0 1.4e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase DUF4847 PF16139.5 GAX17523.1 - 0.0031 17.4 0.2 0.0074 16.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4847) HECT PF00632.25 GAX17523.1 - 0.0065 16.0 0.6 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) ANAPC10 PF03256.16 GAX17524.1 - 6.9e-48 162.7 0.1 9.1e-48 162.3 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 GAX17524.1 - 7.5e-06 26.1 0.3 4.8e-05 23.5 0.2 2.0 2 0 0 2 2 2 1 F5/8 type C domain PI3K_1B_p101 PF10486.9 GAX17524.1 - 0.098 10.4 2.5 0.13 10.1 2.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit VID27_N PF17748.1 GAX17524.1 - 0.36 10.7 4.2 0.59 10.0 4.2 1.4 1 0 0 1 1 1 0 VID27 N-terminal region SDA1 PF05285.12 GAX17524.1 - 0.8 9.1 7.3 1.2 8.5 7.3 1.3 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 GAX17524.1 - 1.1 8.9 6.8 2.3 7.9 6.8 1.5 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 GAX17524.1 - 1.7 6.6 6.2 2.2 6.2 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2722 PF10846.8 GAX17524.1 - 1.9 7.4 9.4 14 4.5 10.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4637 PF15470.6 GAX17524.1 - 2.1 8.1 5.6 4 7.1 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RXT2_N PF08595.11 GAX17524.1 - 2.2 8.3 8.4 5.5 7.0 8.4 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 GAX17524.1 - 3.5 6.7 17.9 0.85 8.7 14.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GAX17524.1 - 4.1 5.4 15.9 5.9 4.9 15.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Spt5_N PF11942.8 GAX17524.1 - 7.8 7.5 20.7 4.2 8.4 17.7 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.32 GAX17525.1 - 1.8e-26 91.9 29.8 1.2e-06 29.1 0.1 10.0 10 1 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17525.1 - 2.5e-07 30.9 2.2 2.4 8.5 0.0 6.8 5 1 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 GAX17525.1 - 0.011 15.0 0.0 2.3 7.4 0.0 3.0 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Acetyltransf_CG PF14542.6 GAX17527.1 - 0.008 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase ATP-grasp_4 PF13535.6 GAX17528.1 - 1.9e-24 86.1 0.0 3.1e-11 43.1 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 GAX17528.1 - 4.4e-23 82.1 0.0 4.4e-11 42.9 0.0 2.9 2 2 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 GAX17528.1 - 2.1e-22 79.9 0.0 7.4e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_D2 PF02786.17 GAX17528.1 - 5.5e-10 39.1 0.0 0.00052 19.6 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 GAX17528.1 - 1.7e-07 31.0 0.1 0.032 14.0 0.0 4.2 4 1 0 4 4 4 2 ATP-grasp in the biosynthetic pathway with Ter operon LAL_C2 PF18603.1 GAX17528.1 - 8.1e-07 29.1 0.0 0.0046 17.1 0.0 2.8 2 0 0 2 2 2 2 L-amino acid ligase C-terminal domain 2 RimK PF08443.11 GAX17528.1 - 0.0044 16.6 0.0 2.1 7.9 0.0 2.7 3 0 0 3 3 3 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAX17528.1 - 0.037 13.6 0.0 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 GAX17529.1 - 2.3e-27 95.6 0.0 2.2e-12 46.8 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_3 PF02655.14 GAX17529.1 - 1.7e-22 80.2 0.0 7.9e-10 39.0 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 GAX17529.1 - 5.9e-20 71.9 0.0 1.3e-08 34.8 0.0 3.7 2 2 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 GAX17529.1 - 4.1e-10 39.5 0.0 0.00078 19.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain LAL_C2 PF18603.1 GAX17529.1 - 2.2e-09 37.3 0.0 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 GAX17529.1 - 8.5e-08 32.0 0.0 0.06 13.1 0.0 4.6 3 2 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 GAX17529.1 - 0.0015 18.1 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.11 GAX17529.1 - 0.0031 17.2 0.0 3.8 7.1 0.0 3.1 3 1 1 4 4 4 2 RimK-like ATP-grasp domain ATPgrasp_TupA PF14305.6 GAX17529.1 - 0.0069 16.2 0.0 4.7 6.9 0.0 2.6 3 0 0 3 3 3 2 TupA-like ATPgrasp Peptidase_S66 PF02016.15 GAX17529.1 - 0.021 14.9 0.0 0.37 10.9 0.0 2.7 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain Kunitz_BPTI PF00014.23 GAX17529.1 - 0.1 12.8 0.1 20 5.5 0.0 2.6 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Nuc_sug_transp PF04142.15 GAX17530.1 - 2.8e-05 23.5 1.6 4.4e-05 22.8 1.6 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter Collectrin PF16959.5 GAX17530.1 - 0.0057 16.4 0.2 0.062 13.1 0.0 2.3 2 0 0 2 2 2 1 Renal amino acid transporter EamA PF00892.20 GAX17530.1 - 0.0096 16.1 1.0 0.0096 16.1 1.0 4.2 3 1 0 3 3 3 1 EamA-like transporter family DUF4781 PF16013.5 GAX17530.1 - 0.018 13.9 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF2530 PF10745.9 GAX17530.1 - 0.19 12.0 1.5 0.53 10.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) CRT-like PF08627.10 GAX17530.1 - 0.21 10.5 14.8 0.075 12.0 0.8 2.9 2 1 1 3 3 3 0 CRT-like, chloroquine-resistance transporter-like Amino_oxidase PF01593.24 GAX17531.1 - 1.9e-46 159.3 0.0 8.4e-35 120.9 0.0 2.1 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAX17531.1 - 1.6e-10 40.7 0.9 9.3e-06 25.1 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX17531.1 - 1e-08 35.3 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX17531.1 - 1.4e-07 31.1 0.0 2.9e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX17531.1 - 0.00012 22.1 0.8 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GAX17531.1 - 0.0004 19.2 0.1 0.025 13.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 GAX17531.1 - 0.001 18.8 1.3 0.084 12.4 0.2 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAX17531.1 - 0.0022 17.3 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAX17531.1 - 0.0048 16.0 0.0 0.057 12.5 0.0 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAX17531.1 - 0.0062 15.7 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAX17531.1 - 0.028 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_6 PF12697.7 GAX17532.1 - 1.9e-15 58.1 0.1 2.6e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX17532.1 - 1.7e-12 47.2 0.0 3.4e-05 23.3 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX17532.1 - 4.8e-10 39.5 0.0 8.9e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 GAX17532.1 - 0.0051 16.4 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region DLH PF01738.18 GAX17532.1 - 0.2 11.2 0.0 6.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family LIDHydrolase PF10230.9 GAX17532.1 - 0.24 10.9 0.0 2.2 7.7 0.0 2.4 2 1 0 2 2 2 0 Lipid-droplet associated hydrolase adh_short PF00106.25 GAX17533.1 - 1.4e-41 142.1 0.1 1.9e-41 141.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX17533.1 - 5.7e-24 85.0 0.1 8.8e-24 84.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX17533.1 - 3.6e-11 43.3 0.1 5.8e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 KR domain EamA PF00892.20 GAX17534.1 - 5.3e-08 33.1 1.7 5.3e-08 33.1 1.7 3.6 2 1 0 2 2 2 1 EamA-like transporter family DUF4212 PF13937.6 GAX17534.1 - 0.076 13.4 1.1 20 5.6 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) PTR2 PF00854.21 GAX17535.1 - 6.5e-39 133.9 18.5 3.9e-24 85.2 5.0 2.1 2 0 0 2 2 2 2 POT family Cwf_Cwc_15 PF04889.12 GAX17536.1 - 2.1 8.0 10.5 3.9 7.1 10.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 GAX17536.1 - 2.2 7.3 11.5 3.3 6.8 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 GAX17536.1 - 2.3 7.5 10.9 3.8 6.7 10.9 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 GAX17536.1 - 2.6 7.5 7.7 4.3 6.8 7.7 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GAX17536.1 - 2.9 6.0 6.7 4.2 5.4 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 GAX17536.1 - 5.3 6.0 8.9 9.3 5.2 8.9 1.3 1 0 0 1 1 1 0 Pes-10 Sigma70_ner PF04546.13 GAX17536.1 - 5.3 6.9 8.8 10 5.9 8.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GAX17536.1 - 7.8 4.5 15.9 11 3.9 15.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi PIG-X PF08320.12 GAX17537.1 - 1.4e-10 41.5 0.4 3.6e-10 40.1 0.0 1.7 1 1 1 2 2 2 1 PIG-X / PBN1 B56 PF01603.20 GAX17538.1 - 1.1e-172 574.7 0.0 1.2e-172 574.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Na_H_Exchanger PF00999.21 GAX17538.1 - 0.036 12.8 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Ank_2 PF12796.7 GAX17539.1 - 4.2e-11 43.3 0.0 1.1e-06 29.1 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX17539.1 - 1.2e-08 35.0 1.0 0.011 16.0 0.0 4.1 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX17539.1 - 1.5e-08 35.0 1.2 0.059 14.0 0.0 4.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17539.1 - 3.5e-08 33.1 4.7 1 10.2 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAX17539.1 - 3.1e-05 24.2 7.9 0.015 15.7 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat NTP_transf_3 PF12804.7 GAX17539.1 - 0.0046 17.3 0.1 0.0084 16.5 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain 2-Hacid_dh_C PF02826.19 GAX17541.1 - 7.9e-41 139.4 0.0 1.1e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX17541.1 - 3.5e-11 42.9 0.0 4.3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain KR PF08659.10 GAX17541.1 - 0.066 13.1 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 KR domain DEDD_Tnp_IS110 PF01548.17 GAX17541.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Transposase DMRL_synthase PF00885.19 GAX17543.1 - 3.1e-50 169.7 0.0 3.9e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DBI_PRT PF02277.17 GAX17543.1 - 0.021 14.1 0.2 0.026 13.8 0.2 1.3 1 0 0 1 1 1 0 Phosphoribosyltransferase TIP49 PF06068.13 GAX17544.1 - 3.3e-140 467.3 0.0 4.3e-140 466.9 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAX17544.1 - 1.6e-22 79.4 0.0 4.3e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAX17544.1 - 2e-10 41.2 0.0 9.6e-07 29.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX17544.1 - 3.7e-10 40.2 0.2 0.00017 21.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAX17544.1 - 7.5e-08 32.9 0.8 7.9e-07 29.6 0.8 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAX17544.1 - 9.9e-08 32.1 0.3 0.004 17.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX17544.1 - 6.8e-07 29.2 0.1 8.5e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GAX17544.1 - 1.3e-05 24.7 0.5 0.0017 17.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX17544.1 - 8.1e-05 22.8 0.1 0.00045 20.4 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 GAX17544.1 - 0.00035 20.2 0.2 0.00066 19.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAX17544.1 - 0.0034 17.1 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAX17544.1 - 0.0078 16.8 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAX17544.1 - 0.01 15.6 0.0 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 GAX17544.1 - 0.011 15.7 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 GAX17544.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 GAX17544.1 - 0.02 14.9 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 GAX17544.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX17544.1 - 0.025 14.5 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 GAX17544.1 - 0.031 14.8 0.0 0.096 13.2 0.0 1.9 1 1 0 1 1 1 0 ABC transporter DNA_pol3_delta PF06144.13 GAX17544.1 - 0.034 13.9 0.3 0.092 12.5 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Rad17 PF03215.15 GAX17544.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain PhoH PF02562.16 GAX17544.1 - 0.053 13.0 0.2 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 GAX17544.1 - 0.07 13.5 2.7 2.6 8.4 2.7 2.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAX17544.1 - 0.071 13.5 0.0 0.27 11.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase TsaE PF02367.17 GAX17544.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAX17544.1 - 0.085 12.4 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAX17544.1 - 0.087 12.1 0.9 0.24 10.7 0.2 2.1 2 1 0 2 2 2 0 Zeta toxin DnaB_C PF03796.15 GAX17544.1 - 0.089 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_PrkA PF08298.11 GAX17544.1 - 0.14 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain Ank_2 PF12796.7 GAX17545.1 - 4.5e-08 33.6 0.0 1.7e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX17545.1 - 8.8e-08 32.3 0.0 0.0011 19.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX17545.1 - 9.5e-06 26.1 0.1 0.14 12.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) GAF PF01590.26 GAX17545.1 - 0.0036 17.9 0.0 0.0068 17.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain Ank_3 PF13606.6 GAX17545.1 - 0.0084 16.5 0.0 1.5 9.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX17545.1 - 0.093 13.2 0.0 0.68 10.5 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeat Glyco_transf_28 PF03033.20 GAX17546.1 - 1.2e-09 38.3 0.0 2.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAX17546.1 - 3.6e-09 35.9 0.0 6.7e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAX17546.1 - 1.3e-06 28.5 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF3592 PF12158.8 GAX17548.1 - 0.0088 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Band_7 PF01145.25 GAX17549.1 - 7.7e-27 94.4 1.0 1.6e-26 93.4 1.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF445 PF04286.12 GAX17549.1 - 0.073 12.9 0.2 0.12 12.1 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF4413 PF14372.6 GAX17549.1 - 0.084 13.3 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) MORN PF02493.20 GAX17550.1 - 0.064 13.2 10.5 0.085 12.8 0.6 3.9 3 0 0 3 3 3 0 MORN repeat SPRY PF00622.28 GAX17554.1 - 4.2e-19 68.8 0.3 9.4e-19 67.7 0.3 1.6 1 1 0 1 1 1 1 SPRY domain SPRY PF00622.28 GAX17555.1 - 4.1e-19 68.9 0.4 7.9e-19 67.9 0.4 1.5 1 1 0 1 1 1 1 SPRY domain TPR_12 PF13424.6 GAX17557.1 - 3.6e-06 27.2 6.1 0.011 16.1 0.3 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX17557.1 - 0.00075 19.0 0.9 0.0029 17.0 0.0 2.0 2 0 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 GAX17557.1 - 0.002 17.9 4.3 3.8 7.5 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX17557.1 - 0.013 16.0 0.2 0.042 14.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17557.1 - 0.043 13.9 7.4 0.92 9.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17557.1 - 3.4 7.6 5.1 45 4.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SPT6_acidic PF14632.6 GAX17558.1 - 1.7 9.3 15.7 1.5 9.5 2.7 3.5 3 0 0 3 3 3 0 Acidic N-terminal SPT6 AP3D1 PF06375.11 GAX17558.1 - 2.8 8.2 23.8 1.4 9.2 6.6 3.6 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Catalase PF00199.19 GAX17559.1 - 2.8e-189 629.1 0.0 3.5e-189 628.8 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAX17559.1 - 1.8e-20 72.9 0.3 8.4e-20 70.8 0.2 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive WGG PF10273.9 GAX17560.1 - 3.8e-21 75.5 0.1 6.4e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 GDI PF00996.18 GAX17561.1 - 1.2e-43 149.3 0.0 3.3e-20 72.0 0.0 3.1 3 0 0 3 3 3 3 GDP dissociation inhibitor CKAP2_C PF15297.6 GAX17561.1 - 0.89 8.6 3.5 6.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus DUF4618 PF15397.6 GAX17562.1 - 0.0013 18.2 0.1 0.002 17.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF3573 PF12097.8 GAX17562.1 - 0.22 10.3 0.1 0.32 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) zf-U1 PF06220.12 GAX17563.1 - 1.7e-06 27.7 0.2 2.9e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 GAX17563.1 - 0.0093 16.2 2.0 0.032 14.5 2.0 1.9 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Semialdhyde_dh PF01118.24 GAX17563.1 - 0.016 15.7 1.0 0.063 13.7 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain MetallophosC PF16370.5 GAX17563.1 - 0.037 14.3 0.4 0.12 12.6 0.4 1.9 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Presenilin PF01080.17 GAX17563.1 - 2.3 6.9 9.7 0.25 10.1 1.8 2.1 2 0 0 2 2 2 0 Presenilin TLD PF07534.16 GAX17564.1 - 6e-21 75.1 0.0 1.7e-20 73.7 0.0 1.7 1 1 0 1 1 1 1 TLD Cob_adeno_trans PF01923.18 GAX17565.1 - 1.1e-53 181.7 0.0 1.8e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF5522 PF17653.1 GAX17565.1 - 8.8e-23 80.0 2.4 1.7e-22 79.1 2.4 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Mito_carr PF00153.27 GAX17566.1 - 1.2e-59 198.3 1.1 4.1e-21 74.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane PF01061.24 GAX17567.1 - 8.3e-34 116.8 14.6 1.2e-33 116.3 14.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX17567.1 - 1.8e-25 90.0 0.0 2.7e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAX17567.1 - 1.1e-05 25.4 0.0 0.073 12.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX17567.1 - 8.6e-05 23.0 0.0 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAX17567.1 - 0.0002 21.3 0.2 0.00037 20.5 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 GAX17567.1 - 0.00039 19.9 0.0 0.0017 17.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX17567.1 - 0.00073 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX17567.1 - 0.0027 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 GAX17567.1 - 0.011 15.4 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX17567.1 - 0.011 15.5 0.4 0.028 14.2 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 GAX17567.1 - 0.017 15.6 0.0 0.048 14.1 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAX17567.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX17567.1 - 0.02 14.8 0.1 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 GAX17567.1 - 0.033 14.7 0.0 0.057 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAX17567.1 - 0.047 13.9 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX17567.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX17567.1 - 0.061 13.3 0.0 0.16 12.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAX17567.1 - 0.062 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAX17567.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 GAX17567.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase cobW PF02492.19 GAX17567.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 GAX17567.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 GAX17567.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 2 0 0 2 2 1 0 NTPase AAA_13 PF13166.6 GAX17567.1 - 0.11 11.1 0.0 0.66 8.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAX17567.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 GAX17567.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ProRS-C_2 PF09181.10 GAX17569.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Abhydrolase_1 PF00561.20 GAX17570.1 - 3.7e-13 49.7 0.0 5.9e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX17570.1 - 1.2e-05 26.1 9.8 1.6e-05 25.6 9.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX17570.1 - 0.00095 18.5 0.1 0.0021 17.4 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 GAX17570.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 GAX17570.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain CBS PF00571.28 GAX17572.1 - 3.4e-19 69.1 0.1 3.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 CBS domain Robl_LC7 PF03259.17 GAX17572.1 - 0.14 11.9 0.1 0.37 10.6 0.0 1.8 1 1 0 1 1 1 0 Roadblock/LC7 domain Ras PF00071.22 GAX17573.1 - 2.9e-50 170.0 0.0 3.3e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX17573.1 - 3.2e-26 91.9 0.0 4.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX17573.1 - 9.9e-12 44.7 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX17573.1 - 0.001 18.6 0.0 0.0022 17.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain COXG PF06240.13 GAX17573.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Porphobil_deam PF01379.20 GAX17574.1 - 2.7e-74 249.1 0.0 3.5e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 GAX17574.1 - 1.8e-17 63.5 0.4 3.4e-17 62.6 0.4 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Metal_resist PF13801.6 GAX17574.1 - 0.06 13.5 1.1 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance RWD PF05773.22 GAX17575.1 - 3.4e-16 59.6 0.2 3.4e-16 59.6 0.2 2.0 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 GAX17575.1 - 0.69 10.4 27.7 13 6.4 27.7 2.7 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Fmp27_SW PF10305.9 GAX17575.1 - 2 9.2 6.0 1.1 10.0 0.4 2.6 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Cu-oxidase PF00394.22 GAX17576.1 - 5e-16 59.2 0.0 1.7e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAX17576.1 - 4.9e-15 55.5 5.5 1.1e-14 54.3 1.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAX17576.1 - 9.6e-11 41.7 0.1 3.8e-05 23.7 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase FAP PF07174.11 GAX17576.1 - 0.0072 15.8 13.2 0.012 15.1 13.2 1.3 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Cornifin PF02389.15 GAX17576.1 - 0.16 12.2 17.8 0.12 12.5 14.0 2.1 2 0 0 2 2 2 0 Cornifin (SPRR) family WD40_like PF17005.5 GAX17577.1 - 0.0018 17.6 0.1 1.9 7.7 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain PQQ_3 PF13570.6 GAX17577.1 - 0.002 18.6 1.8 4 8.0 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain WD40 PF00400.32 GAX17577.1 - 0.0048 17.7 3.8 22 6.1 0.1 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat NiFe_hyd_SSU_C PF14720.6 GAX17577.1 - 0.12 12.8 2.3 0.13 12.6 0.7 1.9 1 1 0 1 1 1 0 NiFe/NiFeSe hydrogenase small subunit C-terminal DNA_pol_B PF00136.21 GAX17578.1 - 2e-116 389.5 0.0 3.8e-116 388.5 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 GAX17578.1 - 6e-38 130.4 0.2 1.9e-37 128.8 0.2 1.9 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 GAX17578.1 - 7e-28 97.7 0.0 1.3e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 GAX17578.1 - 5.4e-20 71.2 9.9 7.6e-20 70.8 8.4 2.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 GAX17578.1 - 0.0058 15.5 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 GAX17578.1 - 0.011 15.4 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Tab2_like PF06485.11 GAX17579.1 - 6.7e-80 268.4 0.0 9.5e-80 267.9 0.0 1.2 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 Cyclin_N PF00134.23 GAX17580.1 - 5.6e-20 71.4 0.2 1.4e-14 53.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX17580.1 - 0.00038 20.5 0.4 0.0044 17.1 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 GAX17580.1 - 0.0036 17.7 0.2 0.042 14.2 0.1 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain Aa_trans PF01490.18 GAX17581.1 - 2.4e-38 131.9 23.4 4.3e-38 131.1 23.4 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.27 GAX17583.1 - 2.5e-30 105.8 0.0 5.1e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX17583.1 - 1.8e-18 67.2 12.8 1.8e-18 67.2 12.8 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 GAX17583.1 - 7.2e-08 32.1 0.2 1.1e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX17583.1 - 0.00054 20.2 0.1 0.0022 18.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX17583.1 - 0.007 16.1 0.1 0.015 15.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAX17583.1 - 0.009 16.5 0.4 0.018 15.6 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX17583.1 - 0.017 15.5 0.4 0.05 14.0 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 GAX17583.1 - 0.036 12.9 0.1 0.36 9.6 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 GAX17583.1 - 0.054 13.2 0.9 0.14 11.9 0.9 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX17583.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 GAX17583.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TMEM223 PF14640.6 GAX17583.1 - 0.095 12.9 0.8 10 6.3 0.0 3.4 3 0 0 3 3 3 0 Transmembrane protein 223 PhoH PF02562.16 GAX17583.1 - 0.14 11.6 0.7 15 5.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_21 PF13304.6 GAX17583.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane_3 PF13748.6 GAX17583.1 - 0.18 11.0 0.1 0.18 11.0 0.1 2.8 3 0 0 3 3 3 0 ABC transporter transmembrane region AAA_24 PF13479.6 GAX17583.1 - 0.19 11.4 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX17583.1 - 0.2 12.2 0.0 0.83 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain CAAD PF14159.6 GAX17583.1 - 6.7 6.6 8.2 1.8 8.5 1.6 3.0 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PDZ PF00595.24 GAX17584.1 - 1.1e-08 35.3 0.0 0.00044 20.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain BTB_2 PF02214.22 GAX17584.1 - 0.0013 19.0 0.0 0.0064 16.8 0.0 2.3 1 0 0 1 1 1 1 BTB/POZ domain PDZ_6 PF17820.1 GAX17584.1 - 0.0015 18.4 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 PDZ domain PTRF_SDPR PF15237.6 GAX17584.1 - 0.026 14.1 2.3 0.11 12.1 0.3 2.1 2 0 0 2 2 2 0 PTRF/SDPR family PDZ_2 PF13180.6 GAX17584.1 - 0.053 13.9 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 PDZ domain CENP-F_leu_zip PF10473.9 GAX17584.1 - 0.082 12.9 3.8 0.73 9.9 0.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 GAX17584.1 - 0.099 12.7 5.5 0.098 12.7 1.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4140 PF13600.6 GAX17584.1 - 0.48 10.9 1.7 7.6 7.0 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.21 GAX17584.1 - 0.57 10.7 3.4 5 7.7 0.3 2.4 2 0 0 2 2 2 0 Spectrin repeat Prefoldin_2 PF01920.20 GAX17584.1 - 5.6 7.0 8.3 1.3 9.1 1.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Peptidase_C2 PF00648.21 GAX17585.1 - 2e-43 148.5 0.0 4.8e-43 147.3 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease NAM-associated PF14303.6 GAX17585.1 - 2.4 8.9 5.1 4.6 7.9 5.1 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TRAM_LAG1_CLN8 PF03798.16 GAX17586.1 - 7.1e-12 45.5 21.5 9.4e-12 45.1 21.5 1.1 1 0 0 1 1 1 1 TLC domain Acetyltransf_8 PF13523.6 GAX17586.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4234 PF14018.6 GAX17586.1 - 0.25 11.5 8.4 0.5 10.5 1.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) HSF_DNA-bind PF00447.17 GAX17587.1 - 1.6e-17 63.9 0.0 2.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Y_phosphatase3 PF13350.6 GAX17589.1 - 1.8e-37 129.6 0.0 2.2e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAX17589.1 - 0.0012 18.5 0.0 0.0032 17.1 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 GAX17589.1 - 0.0014 17.7 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 GAX17589.1 - 0.0023 17.7 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 GAX17589.1 - 0.003 17.1 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DHO_dh PF01180.21 GAX17590.1 - 2.7e-101 338.7 0.0 3.5e-101 338.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 GAX17590.1 - 1.8e-05 24.0 0.0 7.5e-05 21.9 0.0 2.0 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 GAX17590.1 - 0.00045 19.7 0.0 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAX17590.1 - 0.11 11.4 0.1 0.59 9.1 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain HHV-5_US34A PF17087.5 GAX17591.1 - 0.21 11.8 0.4 0.41 10.8 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus US34A protein family MgtE PF01769.16 GAX17591.1 - 8 6.9 12.0 12 6.3 5.9 2.5 1 1 1 2 2 2 0 Divalent cation transporter CCDC-167 PF15188.6 GAX17592.1 - 0.23 11.8 1.1 0.4 11.1 1.1 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Lipid_DES PF08557.10 GAX17592.1 - 1.4 8.5 3.4 0.32 10.5 0.2 1.6 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) UPF0047 PF01894.17 GAX17593.1 - 1.3e-38 131.6 0.0 1.9e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Ysc84 PF04366.12 GAX17594.1 - 1.1e-17 64.0 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator PX PF00787.24 GAX17594.1 - 9.7e-10 38.4 0.1 1.6e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 PX domain SH3BGR PF04908.15 GAX17595.1 - 1.1e-09 38.3 0.2 0.0073 16.4 0.0 3.8 3 0 0 3 3 3 3 SH3-binding, glutamic acid-rich protein zf-MYND PF01753.18 GAX17595.1 - 2.2e-05 24.5 16.1 4.1e-05 23.6 16.1 1.5 1 0 0 1 1 1 1 MYND finger NEMO PF11577.8 GAX17595.1 - 0.038 14.0 1.4 0.16 12.0 0.2 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Sugar_tr PF00083.24 GAX17596.1 - 5.5e-94 315.6 23.9 1.2e-93 314.4 23.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX17596.1 - 1.7e-17 63.4 32.5 1.7e-17 63.4 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFAP1 PF06991.11 GAX17597.1 - 1.6e-46 158.9 25.5 1.6e-46 158.9 25.5 3.0 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing CENP-X PF09415.10 GAX17597.1 - 9.3 6.6 10.3 0.13 12.6 0.7 2.8 2 1 0 2 2 2 0 CENP-S associating Centromere protein X FG-GAP_2 PF14312.6 GAX17598.1 - 4.2e-18 65.3 21.6 1e-06 28.8 0.1 6.5 6 0 0 6 6 6 5 FG-GAP repeat FG-GAP PF01839.23 GAX17598.1 - 0.03 14.4 0.6 2.7 8.2 0.0 3.6 3 0 0 3 3 3 0 FG-GAP repeat RICTOR_phospho PF14665.6 GAX17598.1 - 0.04 14.3 1.6 0.22 11.9 1.6 2.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site FAM70 PF14967.6 GAX17598.1 - 8.4 5.8 5.4 2.2 7.7 0.2 2.4 2 0 0 2 2 2 0 FAM70 protein MatE PF01554.18 GAX17599.1 - 4.1e-30 104.6 22.5 4.6e-15 55.6 2.4 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAX17599.1 - 0.0017 18.4 0.9 0.0017 18.4 0.9 4.8 4 2 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain DUF3612 PF12268.8 GAX17599.1 - 0.045 13.9 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Phage_holin_2_2 PF10746.9 GAX17599.1 - 0.98 9.1 5.8 0.91 9.2 3.6 2.3 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II CSRNP_N PF16019.5 GAX17601.1 - 0.074 13.0 0.3 0.17 11.8 0.2 1.7 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Ribosomal_L17 PF01196.19 GAX17604.1 - 2.4e-32 111.7 1.7 3.2e-32 111.3 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 LRR_8 PF13855.6 GAX17606.1 - 1.1e-29 102.0 42.2 2e-09 37.1 1.1 9.0 4 3 10 14 14 14 12 Leucine rich repeat LRR_4 PF12799.7 GAX17606.1 - 8.2e-25 86.5 43.3 0.002 18.5 0.2 11.2 4 2 10 14 14 14 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX17606.1 - 4.9e-14 50.7 23.4 2 9.3 0.0 13.6 14 1 0 14 14 14 4 Leucine Rich Repeat LRR_6 PF13516.6 GAX17606.1 - 0.16 12.1 36.0 1.2 9.3 0.3 10.6 12 0 0 12 12 12 0 Leucine Rich repeat DNA_pol_phi PF04931.13 GAX17606.1 - 4.4 5.3 6.1 6.9 4.6 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi TMEM43 PF07787.12 GAX17607.1 - 2.5e-54 184.3 0.0 4e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 43 PhoR PF11808.8 GAX17607.1 - 4.2 7.9 0.0 4.2 7.9 0.0 2.8 2 1 1 3 3 3 0 Phosphate regulon sensor protein PhoR EMP70 PF02990.16 GAX17608.1 - 3.3e-173 577.1 1.6 4.2e-173 576.8 1.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4781 PF16013.5 GAX17609.1 - 0.0013 17.6 0.5 0.0026 16.6 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) Methyltransf_32 PF13679.6 GAX17610.1 - 4.3e-30 104.8 0.0 1.1e-29 103.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX17610.1 - 1.7e-05 24.7 0.1 6.7e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TRM13 PF05206.14 GAX17610.1 - 4.4e-05 23.1 0.2 0.003 17.1 0.2 2.6 1 1 1 2 2 2 1 Methyltransferase TRM13 Methyltransf_25 PF13649.6 GAX17610.1 - 0.0053 17.4 0.0 0.015 16.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Rep_fac-A_3 PF08661.11 GAX17611.1 - 3.5e-14 53.0 0.0 3.9e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 MTS PF05175.14 GAX17612.1 - 4.9e-11 42.5 0.1 1.5e-07 31.2 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 GAX17612.1 - 7.1e-10 38.8 0.2 1.1e-09 38.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX17612.1 - 5.8e-07 30.1 0.2 3.1e-06 27.8 0.0 2.2 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX17612.1 - 1.7e-06 27.9 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GAX17612.1 - 5.1e-06 26.3 1.9 0.11 12.1 0.0 2.8 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 GAX17612.1 - 6.1e-05 22.7 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 GAX17612.1 - 0.00019 22.0 0.1 0.00079 20.0 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 GAX17612.1 - 0.0015 18.1 0.0 0.003 17.2 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 GAX17612.1 - 0.0028 17.4 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 GAX17612.1 - 0.0039 17.1 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX17612.1 - 0.0086 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX17612.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.18 GAX17612.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 GAX17612.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AviRa PF11599.8 GAX17612.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 GAX17612.1 - 0.068 13.9 0.0 0.27 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 GAX17612.1 - 0.11 12.2 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Vps23_core PF09454.10 GAX17613.1 - 0.071 13.1 1.2 2 8.4 0.4 2.8 2 0 0 2 2 2 0 Vps23 core domain CENP-B_N PF04218.13 GAX17615.1 - 5.9e-11 41.8 6.0 4e-07 29.6 0.3 2.6 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 GAX17615.1 - 3.2e-10 40.2 1.4 1.3e-05 25.5 0.1 2.7 2 0 0 2 2 2 2 Transposase HTH_23 PF13384.6 GAX17615.1 - 3.6e-07 29.8 0.1 0.0081 15.9 0.0 2.7 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 GAX17615.1 - 4.1e-05 23.6 0.0 0.0043 17.2 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 GAX17615.1 - 0.0001 21.6 0.0 0.0043 16.4 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1_2 PF13022.6 GAX17615.1 - 0.00031 20.9 8.0 0.01 16.0 0.1 3.3 2 1 1 3 3 3 2 Helix-turn-helix of insertion element transposase Phage_CI_repr PF07022.13 GAX17615.1 - 0.0011 19.0 0.2 1.3 9.2 0.0 2.6 2 0 0 2 2 2 2 Bacteriophage CI repressor helix-turn-helix domain HTH_17 PF12728.7 GAX17615.1 - 0.0012 19.0 0.1 1.5 9.1 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_10 PF04967.12 GAX17615.1 - 0.0059 16.4 0.1 0.37 10.6 0.0 2.8 2 0 0 2 2 2 1 HTH DNA binding domain MerR_1 PF13411.6 GAX17615.1 - 0.0097 16.0 0.3 0.23 11.6 0.0 2.6 1 1 1 2 2 2 1 MerR HTH family regulatory protein HTH_30 PF13556.6 GAX17615.1 - 0.014 15.2 0.8 2.9 7.8 0.0 3.5 3 1 0 3 3 3 0 PucR C-terminal helix-turn-helix domain ANT PF03374.14 GAX17615.1 - 0.029 14.7 0.3 0.029 14.7 0.3 3.7 3 1 1 4 4 3 0 Phage antirepressor protein KilAC domain DUF1153 PF06627.11 GAX17615.1 - 0.048 13.8 0.1 6.1 7.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1153) Phage_Nu1 PF07471.12 GAX17615.1 - 0.073 12.8 3.2 1.2 8.9 0.1 2.7 3 0 0 3 3 3 0 Phage DNA packaging protein Nu1 HTH_29 PF13551.6 GAX17615.1 - 0.084 12.9 0.0 12 6.0 0.0 2.9 2 0 0 2 2 2 0 Winged helix-turn helix Terminase_5 PF06056.12 GAX17615.1 - 0.12 12.3 0.1 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DivIC PF04977.15 GAX17615.1 - 1.3 8.9 9.8 4.5 7.1 9.8 2.0 1 0 0 1 1 1 0 Septum formation initiator DUF1323 PF07037.11 GAX17615.1 - 3.8 7.9 14.6 0.55 10.6 0.2 3.5 4 0 0 4 4 2 0 Putative transcription regulator (DUF1323) Dickkopf_N PF04706.12 GAX17615.1 - 8.8 6.9 7.2 3.6 8.1 4.4 1.8 2 0 0 2 2 1 0 Dickkopf N-terminal cysteine-rich region TLD PF07534.16 GAX17616.1 - 1.7e-29 102.8 0.0 4.4e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 TLD RRM_1 PF00076.22 GAX17617.1 - 2.2e-09 37.0 0.1 4.2e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 GAX17617.1 - 7.6e-09 35.3 12.8 1.1e-05 25.2 2.9 2.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SelP_N PF04592.14 GAX17617.1 - 0.11 11.9 11.5 0.73 9.2 9.8 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region zf_CCCH_4 PF18345.1 GAX17617.1 - 0.27 11.3 10.4 0.26 11.4 1.4 2.5 2 0 0 2 2 2 0 Zinc finger domain CDC45 PF02724.14 GAX17617.1 - 1.2 7.4 8.9 1.3 7.2 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Torus PF16131.5 GAX17617.1 - 5.1 7.8 15.4 0.78 10.5 0.6 3.3 3 1 1 4 4 4 0 Torus domain D5_N PF08706.11 GAX17618.1 - 0.059 13.6 0.5 0.061 13.6 0.5 1.1 1 0 0 1 1 1 0 D5 N terminal like ZZ PF00569.17 GAX17619.1 - 9.5e-08 31.7 0.9 2e-07 30.7 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 GAX17619.1 - 0.0023 17.8 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 PB1 domain NBD_C PF17042.5 GAX17619.1 - 1.9 9.0 5.4 23 5.4 1.0 2.5 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain Glyco_trans_2_3 PF13632.6 GAX17621.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_trans_2_3 PF13632.6 GAX17622.1 - 6.1e-14 52.4 0.7 6.1e-14 52.4 0.7 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 GAX17622.1 - 0.009 14.6 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 Cellulose synthase Glyco_tranf_2_3 PF13641.6 GAX17622.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAX17622.1 - 0.03 13.8 0.0 0.081 12.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 Sulfotransfer_3 PF13469.6 GAX17622.1 - 0.034 14.5 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase family Sec23_trunk PF04811.15 GAX17623.1 - 0.00053 19.6 0.0 0.055 13.0 0.0 2.5 2 1 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX17623.1 - 0.0018 18.1 2.4 0.0025 17.6 0.3 2.5 3 1 0 3 3 3 1 Sec23/Sec24 helical domain zinc_ribbon_2 PF13240.6 GAX17623.1 - 1.2 8.9 4.3 3.5 7.5 0.5 3.0 3 0 0 3 3 3 0 zinc-ribbon domain tRNA-synt_1 PF00133.22 GAX17624.1 - 1.5e-217 723.7 0.4 1.9e-217 723.3 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAX17624.1 - 1.4e-24 86.8 0.0 3.2e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAX17624.1 - 5.9e-14 51.6 1.9 0.00067 18.5 0.3 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAX17624.1 - 0.0071 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ion_trans_2 PF07885.16 GAX17625.1 - 3.7e-33 113.3 20.0 8.2e-19 67.4 8.5 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 GAX17625.1 - 1.6e-08 34.1 8.1 4.1e-05 22.9 1.8 2.6 1 1 1 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 GAX17625.1 - 4.7e-08 33.4 2.3 0.0014 19.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX17625.1 - 2.3e-07 29.9 4.1 0.0055 16.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX17625.1 - 1.3e-06 27.8 1.8 0.052 13.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAX17625.1 - 1.2e-05 25.0 3.9 0.057 13.3 0.4 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX17625.1 - 4.8e-05 22.7 1.9 0.076 12.5 0.5 2.5 2 0 0 2 2 2 2 EF hand DUF4456 PF14644.6 GAX17625.1 - 0.0034 17.1 0.1 2.1 8.0 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4456) SPARC_Ca_bdg PF10591.9 GAX17625.1 - 0.0098 16.2 0.6 0.096 13.0 0.5 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GAX17625.1 - 0.056 13.6 0.3 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain MORN PF02493.20 GAX17627.1 - 2e-28 96.6 29.8 4.8e-06 26.2 0.9 7.2 7 0 0 7 7 7 7 MORN repeat FHA PF00498.26 GAX17627.1 - 0.12 12.8 0.2 0.69 10.3 0.0 2.1 1 1 1 2 2 2 0 FHA domain Abhydrolase_3 PF07859.13 GAX17629.1 - 1.2e-08 35.1 0.0 2.3e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX17629.1 - 2.2e-07 30.4 0.1 1.2e-05 24.7 0.1 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAX17629.1 - 1.6e-05 24.5 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAX17629.1 - 0.00098 19.0 0.6 0.069 12.9 0.0 2.8 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAX17629.1 - 0.0066 17.1 0.0 0.016 15.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1749 PF08538.10 GAX17629.1 - 0.0086 15.2 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) COesterase PF00135.28 GAX17629.1 - 0.011 14.6 0.9 0.014 14.3 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family LIDHydrolase PF10230.9 GAX17629.1 - 0.052 13.1 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Arm_vescicular PF18770.1 GAX17629.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor tRNA-synt_1g PF09334.11 GAX17630.1 - 7.6e-94 314.6 0.4 4e-91 305.7 0.4 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAX17630.1 - 4.3e-30 104.5 0.8 1.4e-19 69.8 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 GAX17630.1 - 7.2e-24 83.7 0.1 1.5e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 GAX17630.1 - 6.1e-12 45.5 1.0 7.2e-06 25.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GAX17630.1 - 6.2e-06 25.4 0.1 0.00018 20.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (K) AP3D1 PF06375.11 GAX17630.1 - 1.5 9.1 7.1 1.8 8.7 4.2 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 SMC_N PF02463.19 GAX17631.1 - 0.0001 21.8 0.0 0.039 13.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX17631.1 - 0.00012 22.0 0.1 0.24 11.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 GAX17631.1 - 0.00019 21.6 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX17631.1 - 0.00089 19.8 0.0 0.44 11.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 GAX17631.1 - 0.0063 16.8 0.0 0.017 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 GAX17631.1 - 0.03 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GAX17631.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Pox_A32 PF04665.12 GAX17631.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.6 GAX17631.1 - 0.061 13.1 0.2 0.38 10.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAX17631.1 - 0.07 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 GAX17631.1 - 0.084 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 GAX17631.1 - 0.12 11.7 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin TPR_2 PF07719.17 GAX17633.1 - 4.9e-18 63.7 26.6 0.00022 21.1 0.2 8.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17633.1 - 1.2e-17 63.1 26.0 3.2e-06 27.5 0.1 9.8 4 4 6 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAX17633.1 - 2.1e-17 63.4 13.7 0.00081 19.9 0.2 6.6 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17633.1 - 9.2e-15 53.6 4.2 0.0019 18.3 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAX17633.1 - 2.6e-12 46.7 16.7 0.098 12.8 0.1 6.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17633.1 - 5.6e-12 44.9 10.0 0.0013 18.5 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAX17633.1 - 6.9e-12 44.9 13.1 0.026 14.9 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX17633.1 - 3.8e-10 39.3 9.7 0.0088 15.7 0.2 6.4 5 1 2 7 7 7 3 TPR repeat TPR_12 PF13424.6 GAX17633.1 - 6e-10 39.3 22.8 0.0018 18.5 0.8 7.4 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX17633.1 - 2.4e-05 24.7 11.9 3.7 8.4 0.1 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17633.1 - 0.00015 21.5 4.5 0.9 9.7 0.0 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX17633.1 - 0.0031 18.1 18.5 1.1 10.0 0.8 5.7 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17633.1 - 0.026 14.4 9.4 4.9 7.1 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF484 PF04340.12 GAX17633.1 - 0.047 13.4 3.7 0.084 12.6 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF484 DHHA2 PF02833.14 GAX17633.1 - 0.61 10.3 6.7 11 6.2 0.0 3.5 3 1 1 4 4 4 0 DHHA2 domain PknG_TPR PF16918.5 GAX17633.1 - 1 8.0 10.7 0.1 11.3 1.1 2.8 3 1 1 4 4 4 0 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 GAX17633.1 - 1.4 9.3 9.5 12 6.3 0.2 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat Suf PF05843.14 GAX17633.1 - 5.9 6.8 20.4 7.2 6.5 0.1 4.6 3 2 0 3 3 2 0 Suppressor of forked protein (Suf) CBFB_NFYA PF02045.15 GAX17635.1 - 4.4e-22 78.5 7.0 4.4e-22 78.5 7.0 1.6 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 GAX17635.1 - 4.2 7.3 6.8 5 7.0 6.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ETF_alpha PF00766.19 GAX17637.1 - 1.2e-35 121.4 2.1 2.8e-35 120.2 2.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 GAX17637.1 - 2.5e-20 73.1 2.3 4e-20 72.5 2.3 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain cNMP_binding PF00027.29 GAX17638.1 - 5.3e-12 45.6 0.0 9.9e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Root_cap PF06830.11 GAX17638.1 - 0.0061 16.6 0.0 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 Root cap Rrp40_N PF18311.1 GAX17638.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain zf-UDP PF14569.6 GAX17640.1 - 0.78 9.9 6.0 0.22 11.6 1.4 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger ACBP PF00887.19 GAX17641.1 - 1.1e-15 57.6 0.3 1.8e-15 56.9 0.3 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Kinesin PF00225.23 GAX17643.1 - 4.2e-100 334.9 0.1 8.6e-100 333.9 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX17643.1 - 1.3e-51 174.5 0.1 4e-51 172.9 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Jnk-SapK_ap_N PF09744.9 GAX17643.1 - 0.0053 17.0 13.8 0.0053 17.0 13.8 4.5 3 1 2 5 5 5 1 JNK_SAPK-associated protein-1 Bac_DnaA PF00308.18 GAX17643.1 - 0.01 15.7 0.0 0.039 13.8 0.0 2.0 1 0 0 1 1 1 0 Bacterial dnaA protein Pup PF05639.11 GAX17643.1 - 0.12 13.3 1.6 1.1 10.2 1.2 2.9 1 1 0 1 1 1 0 Pup-like protein Shugoshin_N PF07558.11 GAX17643.1 - 0.25 11.2 5.3 9.2 6.2 0.5 3.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region V-SNARE PF05008.15 GAX17643.1 - 0.53 10.7 16.8 2 8.9 0.3 4.5 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus AAA_16 PF13191.6 GAX17643.1 - 0.85 10.0 0.0 0.85 10.0 0.0 4.0 2 1 0 2 2 2 0 AAA ATPase domain GAS PF13851.6 GAX17643.1 - 3 7.2 42.7 1 8.7 13.0 4.7 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding HSBP1 PF06825.12 GAX17643.1 - 4.5 7.2 9.3 1.4 8.9 0.5 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Pro_isomerase PF00160.21 GAX17644.1 - 5.2e-09 36.6 0.0 7.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spore_YhaL PF14147.6 GAX17644.1 - 2.6 7.8 4.8 4.6 7.0 4.8 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL UAA PF08449.11 GAX17645.1 - 5.2e-49 167.1 18.1 6.4e-49 166.8 18.1 1.1 1 0 0 1 1 1 1 UAA transporter family TMEM252 PF15664.5 GAX17645.1 - 0.21 11.3 2.7 4.3 7.1 0.2 2.5 2 1 0 2 2 2 0 Transmembrane protein 252 family Arf PF00025.21 GAX17647.1 - 1.1e-42 145.4 0.0 1.3e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAX17647.1 - 7.8e-12 45.0 0.0 9.3e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAX17647.1 - 1.3e-09 38.3 0.0 3.3e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX17647.1 - 4.3e-09 36.2 0.0 5.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAX17647.1 - 3.6e-07 29.8 0.0 4.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAX17647.1 - 5.5e-07 29.7 0.0 1e-06 28.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAX17647.1 - 1.6e-06 27.5 0.5 0.0014 17.8 0.1 2.8 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 GAX17647.1 - 0.00011 21.9 0.2 0.015 14.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAX17647.1 - 0.0014 18.2 0.1 0.0034 16.9 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 GAX17647.1 - 0.0036 17.6 0.3 0.091 13.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAX17647.1 - 0.0053 16.7 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 GAX17647.1 - 0.025 14.5 0.0 3.7 7.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 GAX17647.1 - 0.044 14.2 4.1 0.96 9.8 0.2 2.2 1 1 1 2 2 2 0 AAA ATPase domain cobW PF02492.19 GAX17647.1 - 0.089 12.4 0.3 5.7 6.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAX17647.1 - 0.11 12.2 0.0 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT PF02985.22 GAX17648.1 - 8.1e-14 50.6 13.4 5.8e-05 23.0 0.0 9.0 9 0 0 9 9 8 3 HEAT repeat HEAT_EZ PF13513.6 GAX17648.1 - 3.4e-12 46.6 11.4 9.9e-06 25.9 0.0 9.2 11 1 0 11 11 10 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAX17648.1 - 1.7e-11 44.5 2.6 0.022 15.3 0.1 6.0 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 GAX17648.1 - 2.1e-11 44.0 1.4 0.062 13.7 0.0 7.6 4 2 3 7 7 7 3 HEAT repeats MMS19_C PF12460.8 GAX17648.1 - 1.5e-09 37.5 10.6 3e-05 23.3 0.0 4.1 1 1 2 3 3 3 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 GAX17648.1 - 1.8e-08 34.2 3.4 3e-07 30.3 0.5 3.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 GAX17648.1 - 4.4e-08 33.0 4.3 0.0097 15.5 0.0 4.8 3 2 1 4 4 4 2 CLASP N terminal IFRD PF05004.13 GAX17648.1 - 5.1e-06 25.8 14.2 0.00053 19.2 0.2 4.9 2 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 GAX17648.1 - 0.00019 21.5 0.5 0.00019 21.5 0.5 3.1 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 GAX17648.1 - 0.00076 19.4 8.5 0.2 11.6 0.0 5.6 3 2 1 5 5 5 1 Domain of unknown function (DUF3385) Arm PF00514.23 GAX17648.1 - 0.0034 17.4 0.1 1.3 9.1 0.0 4.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat PD-C2-AF1 PF09310.10 GAX17648.1 - 0.045 13.2 1.8 0.3 10.4 0.2 2.4 2 0 0 2 2 2 0 POU domain, class 2, associating factor 1 TIP120 PF08623.10 GAX17648.1 - 0.11 12.2 0.5 4.2 7.1 0.0 2.9 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Urb2 PF10441.9 GAX17648.1 - 5.2 6.9 7.4 3.9 7.4 4.5 2.4 2 1 0 2 2 2 0 Urb2/Npa2 family ETF_QO PF05187.13 GAX17649.1 - 1.4e-37 128.0 0.1 2.6e-37 127.1 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 GAX17649.1 - 2.8e-11 43.2 0.0 4.7e-06 25.9 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX17649.1 - 1.7e-07 31.2 1.0 0.0029 17.2 0.9 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX17649.1 - 9.2e-06 25.8 0.1 3.3e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAX17649.1 - 4e-05 22.5 0.3 6.6e-05 21.8 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAX17649.1 - 0.00013 21.3 0.3 0.00023 20.5 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAX17649.1 - 0.00014 21.2 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX17649.1 - 0.0012 18.1 0.1 0.0031 16.8 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAX17649.1 - 0.0031 16.8 0.0 0.013 14.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAX17649.1 - 0.0045 16.1 0.0 0.0088 15.1 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAX17649.1 - 0.0074 16.3 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAX17649.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX17649.1 - 0.027 15.0 0.1 4.4 7.9 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX17649.1 - 0.12 11.2 0.3 0.27 10.1 0.2 1.6 2 0 0 2 2 2 0 Tryptophan halogenase DDE_Tnp_4 PF13359.6 GAX17651.1 - 1.5e-10 41.0 0.0 2.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAX17651.1 - 0.0032 17.1 0.3 0.0062 16.2 0.1 1.7 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 GAX17651.1 - 0.01 15.6 0.1 0.068 12.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DUF393 PF04134.12 GAX17654.1 - 2.8e-23 83.4 0.0 4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DUF285 PF03382.14 GAX17655.1 - 4.2e-247 804.5 176.7 2.8e-37 127.2 20.4 6.2 1 1 7 8 8 8 8 Mycoplasma protein of unknown function, DUF285 Phage_tail_L PF05100.12 GAX17655.1 - 2.2 7.5 9.5 3.5 6.9 0.0 3.9 1 1 1 4 4 4 0 Phage minor tail protein L DUF285 PF03382.14 GAX17656.1 - 1.3e-173 567.3 99.5 1.9e-37 127.7 14.6 6.0 1 1 5 6 6 6 6 Mycoplasma protein of unknown function, DUF285 DrrA_P4M PF14860.6 GAX17656.1 - 0.00024 20.9 8.8 19 5.2 0.0 7.8 7 1 2 9 9 9 2 DrrA phosphatidylinositol 4-phosphate binding domain DUF285 PF03382.14 GAX17657.1 - 2.3e-116 382.4 75.5 4.8e-33 113.5 16.9 4.1 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 CYYR1 PF10873.8 GAX17658.1 - 0.085 13.3 1.6 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF285 PF03382.14 GAX17659.1 - 3.8e-49 165.4 16.9 2.5e-25 88.6 3.9 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 DUF285 PF03382.14 GAX17660.1 - 8.2e-162 529.2 102.7 3.5e-34 117.2 8.8 6.0 1 1 5 6 6 6 6 Mycoplasma protein of unknown function, DUF285 DrrA_P4M PF14860.6 GAX17660.1 - 0.024 14.5 2.3 29 4.6 0.1 4.5 5 0 0 5 5 5 0 DrrA phosphatidylinositol 4-phosphate binding domain Spectrin_like PF18373.1 GAX17660.1 - 5.7 7.1 10.9 10 6.3 0.4 5.0 5 1 0 5 5 5 0 Spectrin like domain RRM_1 PF00076.22 GAX17661.1 - 7.9e-12 44.8 0.0 8.2e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGA2 PF07543.12 GAX17661.1 - 1.9 8.5 7.4 0.47 10.4 3.8 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 NOA36 PF06524.12 GAX17661.1 - 2.6 7.3 6.0 4.5 6.5 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L26 PF16906.5 GAX17662.1 - 1.3e-33 115.3 2.8 1.6e-33 115.0 2.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAX17662.1 - 0.00032 20.5 1.0 0.00074 19.4 1.0 1.7 1 0 0 1 1 1 1 KOW motif LEAP-2 PF07359.11 GAX17663.1 - 0.86 9.5 5.1 0.36 10.7 1.3 2.1 1 1 1 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Lipid_DES PF08557.10 GAX17664.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Lipid_DES PF08557.10 GAX17665.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) MORN PF02493.20 GAX17667.1 - 3.7e-31 105.2 42.0 1.3e-07 31.1 3.9 7.4 7 0 0 7 7 7 6 MORN repeat DUF35_N PF12172.8 GAX17667.1 - 0.11 12.4 0.5 0.11 12.4 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3048_C PF17479.2 GAX17667.1 - 0.13 12.6 1.0 0.48 10.8 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain MORN_2 PF07661.13 GAX17667.1 - 1.2 9.6 3.6 25 5.5 0.2 4.0 3 0 0 3 3 3 0 MORN repeat variant ArsC PF03960.15 GAX17670.1 - 0.12 12.5 0.1 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 ArsC family DUF5395 PF17373.2 GAX17672.1 - 0.15 12.7 0.0 0.34 11.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5395) DUF2031 PF09592.10 GAX17679.1 - 0.06 12.8 0.5 4.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) FANCF PF11107.8 GAX17679.1 - 0.1 11.8 0.2 3.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Fanconi anemia group F protein (FANCF) Actino_peptide PF14408.6 GAX17679.1 - 0.11 12.7 0.0 29 4.9 0.0 2.7 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes DUF1534 PF07551.11 GAX17679.1 - 0.17 11.6 0.1 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) TerB_N PF13208.6 GAX17682.1 - 0.055 13.2 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 TerB N-terminal domain DUF3474 PF11960.8 GAX17685.1 - 0.05 13.8 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Transglut_i_TM PF14400.6 GAX17687.1 - 0.034 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices VWA PF00092.28 GAX17690.1 - 1.2e-12 48.5 0.6 2e-12 47.7 0.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAX17690.1 - 1.4e-10 41.7 2.0 1.7e-10 41.5 0.6 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX17690.1 - 1.7e-07 31.3 0.1 3.3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GAX17690.1 - 0.00028 20.4 0.1 0.0005 19.5 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein dCache_1 PF02743.18 GAX17690.1 - 0.0064 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Cache domain 3HBOH PF10605.9 GAX17694.1 - 0.098 10.9 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) PKD PF00801.20 GAX17695.1 - 0.14 12.1 0.1 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 PKD domain B3 PF02362.21 GAX17705.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 B3 DNA binding domain Anp1 PF03452.14 GAX17713.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Anp1 CENP-B_dimeris PF09026.10 GAX17713.1 - 2.7 8.4 9.1 5.5 7.4 9.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain F_bP_aldolase PF01116.20 GAX17714.1 - 7.1e-87 291.4 0.0 8.2e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RVT_1 PF00078.27 GAX17715.1 - 8.9e-07 28.6 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT PF02985.22 GAX17716.1 - 1.2e-09 37.6 18.2 0.013 15.7 0.4 6.7 6 0 0 6 6 6 3 HEAT repeat PDZ PF00595.24 GAX17716.1 - 2.4e-08 34.2 0.1 7e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX17716.1 - 4.5e-07 29.6 0.0 1.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX17716.1 - 1.2e-05 25.5 0.1 3.6e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain HEAT_2 PF13646.6 GAX17716.1 - 4.6e-05 23.7 11.8 0.027 14.8 0.9 4.8 4 2 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 GAX17716.1 - 0.0026 17.8 3.2 0.42 10.6 0.1 3.0 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAX17716.1 - 0.025 13.1 0.1 0.26 9.8 0.0 2.2 1 1 1 2 2 2 0 Adaptin N terminal region Arm PF00514.23 GAX17716.1 - 0.07 13.2 0.2 0.37 10.9 0.2 2.2 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Ras PF00071.22 GAX17717.1 - 9.5e-49 165.1 0.0 1.2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX17717.1 - 5.6e-30 104.0 0.0 1.5e-29 102.7 0.0 1.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX17717.1 - 1.1e-09 38.0 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX17717.1 - 9.4e-05 22.5 0.0 0.00026 21.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 GAX17717.1 - 0.00036 20.9 0.1 0.0013 19.1 0.1 1.9 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 GAX17717.1 - 0.0032 16.8 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ArgoMid PF16487.5 GAX17717.1 - 0.019 15.2 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute Septin PF00735.18 GAX17717.1 - 0.042 13.1 0.2 0.078 12.3 0.0 1.6 2 0 0 2 2 2 0 Septin SRPRB PF09439.10 GAX17717.1 - 0.048 13.1 0.0 0.08 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAX17717.1 - 0.057 13.1 0.1 0.096 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAX17717.1 - 0.07 13.0 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAX17717.1 - 0.073 13.4 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 GAX17717.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 GAX17717.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 GAX17717.1 - 0.082 12.0 1.4 2 7.5 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.6 GAX17717.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAX17717.1 - 0.14 12.1 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 GAX17717.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 NTPase Homeobox_KN PF05920.11 GAX17718.1 - 4.4e-15 55.3 0.5 1.3e-14 53.7 0.5 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAX17718.1 - 9.9e-06 25.3 0.4 3.8e-05 23.4 0.2 2.1 2 0 0 2 2 2 1 Homeodomain zf-C3HC4 PF00097.25 GAX17718.1 - 3e-05 23.8 5.9 5.3e-05 23.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX17718.1 - 3.3e-05 23.6 8.2 5.9e-05 22.8 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX17718.1 - 0.00017 21.8 6.5 0.00033 20.9 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAX17718.1 - 0.0042 16.9 4.7 0.0063 16.3 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX17718.1 - 0.0061 16.3 4.7 0.012 15.3 4.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAX17718.1 - 0.0093 16.0 9.6 0.018 15.0 9.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX17718.1 - 0.016 15.0 6.1 0.03 14.2 6.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAX17718.1 - 0.019 15.2 4.5 0.045 14.1 4.5 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX17718.1 - 0.031 14.2 4.6 0.07 13.1 4.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX17718.1 - 2.4 8.3 5.5 6.5 6.9 5.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger rRNA_processing PF08524.11 GAX17719.1 - 2.2e-12 47.2 27.0 3.4e-12 46.6 27.0 1.4 1 1 0 1 1 1 1 rRNA processing Cdc6_C PF09079.11 GAX17719.1 - 0.066 13.2 1.2 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF4407 PF14362.6 GAX17719.1 - 1.1 8.5 9.9 1.3 8.4 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 GAX17719.1 - 1.3 7.2 13.6 1.6 7.0 13.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Flavodoxin_1 PF00258.25 GAX17720.1 - 9.4e-29 100.5 0.0 2.3e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 GAX17720.1 - 1.2e-26 93.6 0.0 2.5e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAX17720.1 - 8.4e-13 48.9 0.1 2.4e-11 44.2 0.1 2.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 GAX17720.1 - 0.038 14.2 0.1 0.61 10.3 0.0 2.6 2 0 0 2 2 2 0 Flavodoxin domain PIN_10 PF18478.1 GAX17720.1 - 0.087 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 PIN like domain UNC-93 PF05978.16 GAX17721.1 - 0.0026 17.5 0.3 0.0026 17.5 0.3 2.6 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 RSN1_7TM PF02714.15 GAX17722.1 - 4.4e-49 167.3 18.9 4.4e-49 167.3 18.9 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX17722.1 - 1.2e-28 99.8 3.3 1.2e-28 99.8 3.3 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX17722.1 - 2e-25 90.1 4.7 4.8e-17 62.7 1.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Peptidase_S10 PF00450.22 GAX17723.1 - 6e-94 315.8 0.0 9.1e-94 315.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase KH_1 PF00013.29 GAX17724.1 - 1.3e-44 149.9 13.4 5.9e-15 54.8 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAX17724.1 - 1.5e-13 50.4 3.8 2.6e-05 24.0 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAX17724.1 - 1.5e-10 40.8 2.3 0.00021 21.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAX17724.1 - 0.014 15.4 3.6 2.1 8.5 0.0 3.4 3 0 0 3 3 3 0 NusA-like KH domain Remorin_N PF03766.13 GAX17724.1 - 0.056 13.5 0.4 0.056 13.5 0.4 2.8 4 0 0 4 4 4 0 Remorin, N-terminal region JIP_LZII PF16471.5 GAX17725.1 - 0.00074 19.6 3.1 0.00074 19.6 3.1 2.5 2 1 0 2 2 2 1 JNK-interacting protein leucine zipper II HTH_21 PF13276.6 GAX17725.1 - 0.0013 18.8 0.0 0.0049 17.0 0.0 2.1 2 1 0 3 3 2 1 HTH-like domain DUF4510 PF14971.6 GAX17725.1 - 0.0014 19.0 0.6 0.0018 18.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4510) Leu_zip PF15294.6 GAX17725.1 - 0.0027 17.3 7.6 0.003 17.1 7.6 1.1 1 0 0 1 1 1 1 Leucine zipper APG17 PF04108.12 GAX17725.1 - 0.01 15.0 3.6 0.011 14.9 3.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DivIVA PF05103.13 GAX17725.1 - 0.013 15.6 3.1 0.013 15.6 3.1 2.2 2 0 0 2 2 2 0 DivIVA protein HEPN PF05168.14 GAX17725.1 - 0.021 14.9 0.9 0.043 14.0 0.8 1.6 1 1 0 1 1 1 0 HEPN domain RE_TdeIII PF09520.10 GAX17725.1 - 0.023 14.4 1.6 0.026 14.2 1.6 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII FlaC_arch PF05377.11 GAX17725.1 - 0.067 13.6 8.2 0.29 11.5 1.6 2.7 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Med30 PF11315.8 GAX17725.1 - 0.069 13.4 6.6 0.083 13.1 6.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF4337 PF14235.6 GAX17725.1 - 0.079 13.1 4.3 0.09 12.9 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) zf-C4H2 PF10146.9 GAX17725.1 - 0.099 12.9 7.9 0.11 12.8 7.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein GED PF02212.18 GAX17725.1 - 0.26 11.5 7.5 0.14 12.3 2.7 2.1 1 1 1 2 2 2 0 Dynamin GTPase effector domain Cnn_1N PF07989.11 GAX17725.1 - 0.4 10.9 10.5 0.08 13.1 4.1 2.2 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 GAX17725.1 - 0.48 10.9 17.4 0.084 13.3 6.6 2.9 2 2 0 2 2 2 0 Cell division protein ZapB Atg14 PF10186.9 GAX17725.1 - 0.55 9.3 8.0 0.62 9.1 8.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ax_dynein_light PF10211.9 GAX17725.1 - 0.57 10.1 10.7 2.5 8.0 10.2 1.9 1 1 0 1 1 1 0 Axonemal dynein light chain CCDC92 PF14916.6 GAX17725.1 - 1.2 9.0 7.1 10 6.0 2.8 3.1 2 1 0 2 2 2 0 Coiled-coil domain of unknown function NRBF2 PF08961.10 GAX17725.1 - 1.7 8.2 8.6 1.2 8.7 6.1 2.0 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TMF_TATA_bd PF12325.8 GAX17725.1 - 1.9 8.7 14.8 4.2 7.6 14.8 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding KxDL PF10241.9 GAX17725.1 - 2 8.7 8.8 1.4 9.2 2.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein BLOC1_2 PF10046.9 GAX17725.1 - 2.3 8.6 11.6 1.6 9.1 5.2 2.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 GAX17725.1 - 2.3 8.5 11.9 0.84 9.9 3.8 2.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain PikAIV_N PF18605.1 GAX17725.1 - 2.8 7.6 12.3 0.19 11.4 1.2 3.5 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DivIC PF04977.15 GAX17725.1 - 3.2 7.6 12.6 0.13 12.1 2.8 2.8 2 2 1 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 GAX17725.1 - 4.5 7.3 11.2 13 5.8 11.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RNA_pol_Rpb2_6 PF00562.28 GAX17727.1 - 9.8e-125 416.6 0.1 1.5e-124 416.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAX17727.1 - 4.6e-60 202.6 0.0 7e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GAX17727.1 - 9.7e-48 162.3 0.0 1.7e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAX17727.1 - 5.5e-27 94.0 0.2 1.3e-26 92.8 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 GAX17727.1 - 2.3e-19 69.7 2.9 7.1e-19 68.1 2.9 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.16 GAX17727.1 - 1.6e-08 34.6 0.1 3.7e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 GAX17727.1 - 2.5e-06 27.7 0.0 5.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 Cu_amine_oxid PF01179.20 GAX17728.1 - 2.8e-152 507.4 0.0 3.7e-152 507.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAX17728.1 - 3.6e-10 40.1 0.1 2e-09 37.8 0.1 2.3 2 1 0 2 2 2 1 Copper amine oxidase, N3 domain Lac_bphage_repr PF06543.12 GAX17728.1 - 0.19 11.7 0.4 39 4.3 0.0 2.9 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor SET PF00856.28 GAX17731.1 - 2.6e-14 53.9 0.0 8.6e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAX17731.1 - 5.1e-12 46.6 0.1 4e-11 43.7 0.1 2.3 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding DUF4908 PF16252.5 GAX17732.1 - 0.013 15.1 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) RNA_pol_Rpc34 PF05158.12 GAX17733.1 - 2.4e-50 171.8 2.8 9.3e-44 150.2 0.6 2.1 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 GAX17733.1 - 0.007 16.5 0.1 0.019 15.1 0.1 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DASH_Duo1 PF08651.10 GAX17733.1 - 0.019 14.7 0.0 0.07 12.9 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF4527 PF15030.6 GAX17733.1 - 0.023 14.2 0.4 0.041 13.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) TFIIE_alpha PF02002.17 GAX17733.1 - 0.037 13.9 0.1 0.098 12.5 0.1 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit DUF3458_C PF17432.2 GAX17734.1 - 3.4e-98 329.0 6.5 3.4e-98 329.0 6.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 GAX17734.1 - 1.9e-53 181.2 0.1 4.1e-53 180.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 GAX17734.1 - 1.2e-23 83.3 0.1 4.6e-23 81.5 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 GAX17734.1 - 1.9e-15 57.5 0.1 4.7e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 GAX17734.1 - 0.086 13.2 0.2 0.49 10.8 0.2 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase CBM_X2 PF03442.14 GAX17734.1 - 0.095 12.8 0.4 0.73 10.0 0.1 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain X2 MTS PF05175.14 GAX17735.1 - 4.3e-12 45.9 0.1 1e-10 41.5 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX17735.1 - 8.1e-09 35.3 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 GAX17735.1 - 2.3e-06 27.5 0.0 0.00015 21.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX17735.1 - 2.2e-05 25.0 0.0 5.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX17735.1 - 0.0002 21.2 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 GAX17735.1 - 0.00088 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Cons_hypoth95 PF03602.15 GAX17735.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 GAX17735.1 - 0.018 14.9 0.0 0.052 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 GAX17735.1 - 0.022 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.12 GAX17735.1 - 0.027 15.2 0.0 0.097 13.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 GAX17735.1 - 0.05 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 GAX17735.1 - 0.098 13.3 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Solute_trans_a PF03619.16 GAX17736.1 - 2.6e-92 309.1 15.9 4.3e-92 308.4 15.9 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2975 PF11188.8 GAX17736.1 - 1 9.2 5.1 3.1 7.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Solute_trans_a PF03619.16 GAX17737.1 - 1.6e-91 306.5 11.5 1.6e-91 306.5 11.5 1.6 2 0 0 2 2 2 1 Organic solute transporter Ostalpha KH_1 PF00013.29 GAX17738.1 - 2.5e-40 136.1 0.0 2.8e-12 46.3 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAX17738.1 - 4.4e-08 32.8 0.1 0.14 12.0 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAX17738.1 - 0.00018 21.3 0.0 1 9.3 0.0 3.3 3 0 0 3 3 3 2 KH domain NfeD PF01957.18 GAX17738.1 - 0.012 16.0 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Foie-gras_1 PF11817.8 GAX17738.1 - 0.62 9.6 4.2 0.4 10.2 0.3 2.1 2 0 0 2 2 2 0 Foie gras liver health family 1 UQ_con PF00179.26 GAX17739.1 - 6.5e-33 113.3 0.0 8.8e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Met_synt_B12 PF02965.17 GAX17740.1 - 1.1e-107 359.6 0.0 1.9e-107 358.8 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 GAX17740.1 - 3.5e-68 230.3 0.0 7.9e-68 229.2 0.0 1.6 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 GAX17740.1 - 6.6e-47 160.2 0.3 1.2e-46 159.3 0.3 1.5 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 GAX17740.1 - 1.6e-25 89.3 0.1 1.6e-25 89.3 0.1 2.1 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 GAX17740.1 - 2.6e-18 66.2 0.1 1.2e-16 60.8 0.1 2.8 2 0 0 2 2 2 1 B12 binding domain Phage_holin_3_6 PF07332.11 GAX17742.1 - 0.04 13.9 1.6 0.04 13.9 1.6 2.3 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III YchF-GTPase_C PF06071.13 GAX17743.1 - 1.4e-36 124.5 0.8 4.1e-36 123.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAX17743.1 - 1.8e-20 73.1 0.0 5.6e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX17743.1 - 9.9e-06 25.2 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF3390 PF11870.8 GAX17743.1 - 0.063 13.7 0.1 2.5 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3390) LacI PF00356.21 GAX17744.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.0 3 1 0 3 3 3 0 Bacterial regulatory proteins, lacI family Uds1 PF15456.6 GAX17745.1 - 0.02 15.0 0.3 0.044 14.0 0.1 1.7 2 0 0 2 2 2 0 Up-regulated During Septation Mac PF12464.8 GAX17745.1 - 0.48 10.7 2.5 4 7.7 0.4 2.6 2 1 0 2 2 2 0 Maltose acetyltransferase Methyltransf_11 PF08241.12 GAX17746.1 - 1.7e-20 73.5 0.0 3.2e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX17746.1 - 1.7e-18 67.1 0.0 3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX17746.1 - 3e-16 59.6 0.0 5.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX17746.1 - 2.9e-15 56.3 0.0 3.7e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAX17746.1 - 2.3e-14 53.6 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX17746.1 - 6.6e-12 46.0 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX17746.1 - 1.4e-09 37.6 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAX17746.1 - 8e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 GAX17746.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_20 PF12147.8 GAX17746.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 GAX17746.1 - 0.062 13.1 0.0 1.4 8.6 0.0 2.3 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 GAX17746.1 - 0.15 11.7 0.0 0.61 9.6 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DREV PF05219.12 GAX17746.1 - 0.17 11.0 0.0 0.33 10.0 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase GATase_4 PF13230.6 GAX17747.1 - 7.5e-59 198.8 0.0 7.4e-57 192.3 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAX17747.1 - 0.0003 21.0 0.0 0.00057 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain JmjC PF02373.22 GAX17748.1 - 3.6e-17 62.8 0.0 9.8e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GAX17748.1 - 5e-15 55.9 0.0 1.5e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX17748.1 - 0.0032 17.0 0.5 0.012 15.1 0.1 2.1 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_1 PF00190.22 GAX17748.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Cupin Aminotran_5 PF00266.19 GAX17750.1 - 7.2e-12 44.9 0.0 2.5e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V EF-hand_1 PF00036.32 GAX17751.1 - 1.1e-07 30.8 1.3 2.4e-07 29.8 1.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX17751.1 - 1.9e-07 30.4 0.8 3.4e-07 29.7 0.8 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAX17751.1 - 9.6e-06 26.0 0.5 1.3e-05 25.6 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX17751.1 - 1.1e-05 25.1 0.4 1.9e-05 24.4 0.4 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAX17751.1 - 3.2e-05 23.2 0.3 5.6e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 EF hand Ribosomal_S17_N PF16205.5 GAX17752.1 - 0.061 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal Atg14 PF10186.9 GAX17753.1 - 2.9e-09 36.4 13.6 6.7e-08 32.0 13.6 2.1 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sec8_exocyst PF04048.14 GAX17753.1 - 0.029 14.3 0.6 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain CLZ PF16526.5 GAX17753.1 - 0.9 9.9 4.5 12 6.3 0.7 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PseudoU_synth_2 PF00849.22 GAX17755.1 - 3.6e-23 82.4 0.0 6.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase zf-C2H2_3rep PF18868.1 GAX17755.1 - 0.039 14.6 0.2 0.38 11.4 0.1 2.2 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_12 PF18658.1 GAX17755.1 - 0.066 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 GAX17755.1 - 0.97 9.8 5.2 1.3 9.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAX17755.1 - 5.5 7.5 6.8 17 6.0 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LRR_4 PF12799.7 GAX17756.1 - 3.3e-22 78.2 48.4 0.00023 21.5 0.2 12.4 9 2 7 16 16 16 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX17756.1 - 1.8e-20 72.5 56.7 4.1e-05 23.3 0.1 10.5 4 3 7 12 12 12 7 Leucine rich repeat LRRNT_2 PF08263.12 GAX17756.1 - 9.7e-10 38.6 8.1 0.00021 21.5 0.1 3.6 3 0 0 3 3 3 2 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GAX17756.1 - 4.3e-06 26.5 44.5 7.2 7.6 0.4 16.3 16 2 1 17 17 17 2 Leucine Rich Repeat Ephrin_rec_like PF07699.13 GAX17756.1 - 0.00072 19.3 8.1 0.01 15.5 2.0 2.4 2 0 0 2 2 2 2 Putative ephrin-receptor like LRR_6 PF13516.6 GAX17756.1 - 0.0013 18.6 43.0 5.1 7.4 0.2 14.3 16 0 0 16 16 16 1 Leucine Rich repeat EF-hand_5 PF13202.6 GAX17756.1 - 0.12 11.9 0.2 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 EF hand TNFR_c6 PF00020.18 GAX17756.1 - 0.25 11.8 6.2 8.6 6.9 1.6 2.6 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region F1F0-ATPsyn_F PF10791.9 GAX17757.1 - 0.068 13.7 1.1 0.11 13.0 0.3 1.7 1 1 1 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Asp_Arg_Hydrox PF05118.15 GAX17758.1 - 4.5e-38 130.5 0.0 6.7e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase MoCF_biosynth PF00994.24 GAX17759.1 - 1.7e-28 99.1 0.0 3.1e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 GAX17759.1 - 3.3e-23 82.6 0.0 2.6e-22 79.7 0.0 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SET PF00856.28 GAX17760.1 - 5.2e-12 46.5 0.0 4.9e-06 27.0 0.0 3.8 2 2 0 3 3 3 2 SET domain NUDIX PF00293.28 GAX17761.1 - 1.3e-17 64.0 0.0 1.6e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain XPC-binding PF09280.11 GAX17761.1 - 0.0014 18.3 2.5 0.0023 17.6 2.5 1.3 1 0 0 1 1 1 1 XPC-binding domain Nuc_sug_transp PF04142.15 GAX17763.1 - 5.8e-57 193.2 21.6 7.4e-57 192.9 21.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAX17763.1 - 5.6e-08 33.1 24.3 0.00014 22.1 6.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX17763.1 - 1.2e-07 31.3 22.3 2e-07 30.5 22.3 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 GAX17763.1 - 7.3e-05 22.1 18.0 0.00011 21.5 18.0 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 GAX17763.1 - 0.39 10.0 20.4 1.8 7.8 20.4 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family GFO_IDH_MocA PF01408.22 GAX17764.1 - 8.4e-12 46.0 0.0 7.9e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAX17764.1 - 5.6e-07 29.6 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DNA_III_psi PF03603.13 GAX17764.1 - 0.013 15.8 0.2 0.021 15.1 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase III psi subunit NAD_binding_3 PF03447.16 GAX17764.1 - 0.052 14.2 0.0 0.096 13.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ox_reductase_C PF08635.10 GAX17764.1 - 0.06 13.0 0.0 0.38 10.4 0.0 2.1 1 1 1 2 2 2 0 Putative oxidoreductase C terminal domain Glyco_hydro_cc PF11790.8 GAX17765.1 - 3.3e-52 177.4 2.3 4.1e-52 177.1 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core VIT1 PF01988.19 GAX17767.1 - 6.6e-11 42.5 7.8 9.3e-10 38.7 7.8 2.3 1 1 0 1 1 1 1 VIT family Nuc_sug_transp PF04142.15 GAX17768.1 - 3.4e-59 200.6 23.4 4.1e-59 200.3 23.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAX17768.1 - 7.2e-09 35.3 21.3 1.7e-08 34.1 21.2 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX17768.1 - 1e-08 35.5 26.0 0.00035 20.8 7.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX17768.1 - 1.2e-07 31.2 20.5 1.9e-06 27.4 20.6 2.3 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 GAX17768.1 - 0.00013 21.4 18.7 0.00032 20.1 18.4 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF4131 PF13567.6 GAX17768.1 - 0.021 14.5 0.0 0.021 14.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) TPR_2 PF07719.17 GAX17769.1 - 1.2e-18 65.6 3.2 7.9e-07 28.7 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17769.1 - 3.4e-16 58.3 1.3 1.7e-06 27.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX17769.1 - 6e-13 48.2 5.0 9.4e-08 31.6 0.1 3.4 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 GAX17769.1 - 1.2e-09 38.2 1.2 0.0024 18.5 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.31 GAX17769.1 - 1.4e-09 37.9 1.9 3.4e-09 36.7 0.3 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.6 GAX17769.1 - 3.8e-08 33.8 6.2 4.8e-05 23.9 1.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX17769.1 - 1.3e-07 32.0 3.4 6.4e-05 23.4 0.1 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX17769.1 - 1.1e-06 28.8 12.1 0.002 18.4 3.2 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX17769.1 - 6.1e-06 26.3 1.2 0.037 14.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17769.1 - 1.1e-05 25.1 5.6 0.0069 16.3 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17769.1 - 1.4e-05 24.9 3.5 0.041 14.1 0.0 4.0 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX17769.1 - 0.00018 21.7 1.6 0.04 14.3 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX17769.1 - 0.0017 18.4 0.3 0.068 13.2 0.1 2.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 GAX17769.1 - 0.0024 18.4 2.8 0.32 11.7 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat BTAD PF03704.17 GAX17769.1 - 0.009 16.5 5.2 0.36 11.3 0.1 3.2 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 GAX17769.1 - 0.009 15.9 10.1 0.089 12.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Mu-like_Pro PF10123.9 GAX17769.1 - 4 6.9 18.1 4.9 6.6 10.8 2.4 1 1 1 2 2 2 0 Mu-like prophage I protein MAS20 PF02064.15 GAX17769.1 - 4.7 7.3 0.0 4.7 7.3 0.0 4.0 3 1 0 3 3 2 0 MAS20 protein import receptor DUF3365 PF11845.8 GAX17769.1 - 6.2 7.1 6.8 3.2 8.1 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) UQ_con PF00179.26 GAX17770.1 - 5.7e-37 126.5 0.0 8.2e-37 126.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX17770.1 - 0.0026 18.1 0.0 0.0047 17.2 0.0 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 GAX17770.1 - 0.034 14.0 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 GAX17770.1 - 0.09 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF1336 PF07059.12 GAX17771.1 - 5.3e-51 173.9 0.0 8.8e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) RNA_pol_Rpb6 PF01192.22 GAX17772.1 - 3.9e-17 61.9 0.3 5.8e-17 61.4 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 PP_kinase PF02503.17 GAX17772.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Polyphosphate kinase middle domain Pkinase PF00069.25 GAX17773.1 - 1.1e-25 90.5 0.0 1.9e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX17773.1 - 3.9e-10 39.4 0.0 6.6e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX17773.1 - 0.07 13.0 0.3 0.2 11.6 0.1 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family CHCH PF06747.13 GAX17774.1 - 0.0013 18.9 5.1 0.0018 18.3 5.1 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 GAX17774.1 - 0.0015 18.8 3.6 0.0023 18.2 3.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 GAX17774.1 - 0.0079 16.2 1.4 0.01 15.9 1.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 GAX17774.1 - 0.069 13.2 4.6 0.1 12.6 4.6 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Rtt106 PF08512.12 GAX17775.1 - 4.9e-15 55.7 0.0 7.8e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Cwf_Cwc_15 PF04889.12 GAX17775.1 - 0.031 14.0 17.5 0.047 13.4 17.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAX17775.1 - 7.2 5.8 25.0 12 5.1 25.0 1.4 1 0 0 1 1 1 0 NOA36 protein CNDH2_C PF16858.5 GAX17775.1 - 7.4 6.4 13.1 11 5.8 13.1 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Exostosin PF03016.15 GAX17776.1 - 3.5e-14 52.7 1.8 2.2e-13 50.1 1.8 2.1 1 1 0 1 1 1 1 Exostosin family Carb_anhydrase PF00194.21 GAX17777.1 - 2.2e-26 92.9 0.8 7.3e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase TarH PF02203.15 GAX17777.1 - 0.027 14.4 1.9 0.047 13.6 1.9 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue SOR_SNZ PF01680.17 GAX17778.1 - 4.2e-98 327.2 6.9 6.6e-98 326.5 6.9 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 GAX17778.1 - 1.2e-07 31.3 6.7 6.6e-07 28.9 0.4 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 GAX17778.1 - 2.6e-05 23.5 0.2 0.021 13.9 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GAX17778.1 - 0.00059 19.4 0.1 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 GAX17778.1 - 0.0036 17.3 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 GAX17778.1 - 0.0043 16.5 3.4 0.017 14.5 0.3 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase OMPdecase PF00215.24 GAX17778.1 - 0.0076 15.9 0.1 1.9 8.0 0.0 2.3 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family NanE PF04131.14 GAX17778.1 - 0.013 14.7 2.1 0.033 13.4 0.1 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 GAX17778.1 - 0.023 13.7 0.2 0.032 13.2 0.2 1.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 GAX17778.1 - 0.04 13.1 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase RVT_2 PF07727.14 GAX17779.1 - 1.9e-22 80.1 0.5 5.8e-22 78.5 0.5 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GST_C PF00043.25 GAX17779.1 - 0.014 15.6 0.6 0.042 14.1 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain zf-CCHC PF00098.23 GAX17779.1 - 0.77 9.9 9.2 0.091 12.9 4.9 1.8 2 0 0 2 2 2 0 Zinc knuckle SDA1 PF05285.12 GAX17779.1 - 5.6 6.3 12.2 17 4.7 12.2 1.8 1 0 0 1 1 1 0 SDA1 PGM_PMM_II PF02879.16 GAX17781.1 - 2.1e-21 76.5 0.0 4.6e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 GAX17781.1 - 1.2e-20 73.6 0.0 2.8e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAX17781.1 - 6.5e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III BING4CT PF08149.11 GAX17782.1 - 7e-31 105.9 0.0 9.6e-30 102.2 0.0 2.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 GAX17782.1 - 2.1e-08 34.7 0.1 0.00023 21.9 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17782.1 - 0.00036 20.8 0.1 4.5 7.6 0.0 5.1 3 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Cas_Csy4 PF09618.10 GAX17782.1 - 0.22 11.7 3.6 0.61 10.2 3.6 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) TPR_12 PF13424.6 GAX17783.1 - 6.1e-18 64.9 0.0 1.2e-09 38.3 0.0 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17783.1 - 5.9e-09 35.5 0.0 0.022 14.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17783.1 - 6.8e-09 35.2 0.6 0.096 12.9 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17783.1 - 7.8e-09 35.0 0.4 0.094 12.6 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17783.1 - 1.1e-05 25.3 0.0 0.061 13.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17783.1 - 1.6e-05 24.6 0.1 5 7.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX17783.1 - 0.00079 19.9 0.0 0.033 14.7 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17783.1 - 0.022 15.6 0.1 1.1e+02 4.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX17783.1 - 0.042 14.5 0.1 87 3.9 0.0 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX17783.1 - 0.054 13.9 0.3 67 4.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PKI PF02827.16 GAX17783.1 - 1.9 8.8 4.5 1.5 9.1 0.3 2.4 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Ank_2 PF12796.7 GAX17784.1 - 2.5e-33 114.5 0.1 1.9e-09 38.0 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX17784.1 - 4.5e-28 96.9 1.5 2.3e-06 27.8 0.0 6.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX17784.1 - 4.8e-25 87.6 4.2 1e-07 32.3 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17784.1 - 7.6e-20 68.9 11.2 0.07 13.7 0.0 10.2 10 1 1 11 11 11 5 Ankyrin repeat Ank PF00023.30 GAX17784.1 - 2.3e-18 65.7 7.5 0.044 14.2 0.0 8.6 8 1 1 9 9 9 6 Ankyrin repeat bPH_2 PF03703.14 GAX17785.1 - 4.2e-12 46.1 0.1 6.2e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial PH domain bPH_3 PF14470.6 GAX17785.1 - 0.084 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain DUF3291 PF11695.8 GAX17786.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) AA_permease_2 PF13520.6 GAX17787.1 - 4.8e-34 117.9 24.8 4.8e-34 117.9 24.8 1.5 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAX17787.1 - 1.1e-22 80.3 19.4 1.1e-22 80.3 19.4 1.7 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 GAX17787.1 - 1.5e-06 28.2 7.9 1.5e-06 28.2 7.9 3.2 4 0 0 4 4 4 1 C-terminus of AA_permease Tfb2 PF03849.14 GAX17788.1 - 9.2e-84 281.4 0.0 1.1e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GAX17788.1 - 2.8e-11 43.7 2.2 7.5e-11 42.3 2.2 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 GAX17788.1 - 5.1e-05 23.4 0.0 0.0029 17.8 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain SQS_PSY PF00494.19 GAX17788.1 - 0.03 13.8 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 Squalene/phytoene synthase Pol_alpha_B_N PF08418.10 GAX17789.1 - 1.5 8.7 21.4 1.8 8.5 13.4 3.0 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Peptidase_M50B PF13398.6 GAX17790.1 - 4.8e-48 163.5 12.1 5.8e-48 163.2 12.1 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 GAX17790.1 - 1.2 8.3 4.3 0.41 9.9 0.6 1.8 1 1 1 2 2 2 0 Peptidase family M50 Telomere_reg-2 PF10193.9 GAX17791.1 - 0.013 15.9 0.5 0.019 15.4 0.5 1.3 1 0 0 1 1 1 0 Telomere length regulation protein LRRFIP PF09738.9 GAX17791.1 - 0.014 14.9 9.5 0.014 14.9 9.5 1.8 1 1 1 2 2 2 0 LRRFIP family MPS2 PF17060.5 GAX17791.1 - 0.057 12.7 5.1 0.067 12.5 5.1 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 ATG16 PF08614.11 GAX17791.1 - 0.08 13.2 11.5 0.1 12.8 11.0 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 GAX17791.1 - 0.097 13.1 7.9 0.15 12.4 7.9 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) V_ATPase_I PF01496.19 GAX17791.1 - 0.24 9.3 3.6 0.22 9.4 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DHR10 PF18595.1 GAX17791.1 - 0.4 10.7 14.1 0.95 9.5 13.9 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Vfa1 PF08432.10 GAX17791.1 - 0.4 11.0 7.2 0.42 10.9 6.5 1.3 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM76 PF16046.5 GAX17791.1 - 1.3 8.3 12.0 0.91 8.8 8.6 1.9 1 1 1 2 2 2 0 FAM76 protein Peptidase_S46 PF10459.9 GAX17791.1 - 2 7.0 6.4 3.2 6.3 6.4 1.4 1 1 0 1 1 1 0 Peptidase S46 DUF4407 PF14362.6 GAX17791.1 - 2.8 7.2 6.1 3.4 6.9 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cpn60_TCP1 PF00118.24 GAX17792.1 - 4.2e-153 510.5 0.6 4.7e-153 510.3 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NAC PF01849.18 GAX17794.1 - 7.7e-23 80.2 0.5 1.7e-22 79.2 0.5 1.6 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 GAX17794.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain FG-GAP_2 PF14312.6 GAX17795.1 - 1.2e-22 79.9 58.9 0.0023 18.1 2.5 11.3 11 0 0 11 11 11 9 FG-GAP repeat WW PF00397.26 GAX17795.1 - 2e-11 43.8 1.8 2e-11 43.8 1.8 1.9 2 0 0 2 2 2 1 WW domain Glyco_hyd_101C PF17451.2 GAX17795.1 - 0.048 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain DUF1640 PF07798.11 GAX17795.1 - 0.057 13.5 2.5 0.13 12.4 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FG-GAP_2 PF14312.6 GAX17796.1 - 4.7e-25 87.6 56.7 1.2e-05 25.5 1.0 11.4 11 0 0 11 11 11 9 FG-GAP repeat FG-GAP_2 PF14312.6 GAX17797.1 - 1.3e-15 57.3 25.0 0.00018 21.7 0.3 6.1 6 0 0 6 6 6 5 FG-GAP repeat Vitelline_membr PF10542.9 GAX17799.1 - 0.19 11.6 0.8 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region Band_7 PF01145.25 GAX17800.1 - 9.7e-27 94.1 2.5 1.4e-26 93.6 1.0 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.8 GAX17800.1 - 0.08 13.1 0.6 0.14 12.4 0.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 MRP-S27 PF10037.9 GAX17800.1 - 0.082 11.8 1.5 0.12 11.2 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF1104 PF06518.11 GAX17800.1 - 1.3 9.5 5.5 8.3 6.9 4.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) polyprenyl_synt PF00348.17 GAX17802.1 - 1.6e-96 322.3 0.1 2.1e-96 321.9 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3180 PF11377.8 GAX17802.1 - 0.56 10.3 3.5 0.34 11.0 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DUF1800 PF08811.11 GAX17803.1 - 3.3e-42 145.0 0.0 8.8e-24 84.3 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX17803.1 - 8.5e-31 107.4 0.1 2.1e-30 106.1 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX17803.1 - 1e-05 25.5 0.3 0.00021 21.3 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DUF3751 PF12571.8 GAX17803.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage tail-collar fibre protein Dicty_CTDC PF00526.18 GAX17806.1 - 2.6e-07 30.4 5.0 2.6e-07 30.4 5.0 3.9 3 0 0 3 3 3 1 Dictyostelium (slime mold) repeat DUF4988 PF16378.5 GAX17808.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF1800 PF08811.11 GAX17811.1 - 2.8e-39 135.4 0.0 7.8e-23 81.2 0.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX17811.1 - 1.7e-33 116.3 0.1 2.6e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX17811.1 - 0.049 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF1800 PF08811.11 GAX17812.1 - 8.4e-48 163.5 0.2 6.4e-27 94.6 0.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX17812.1 - 3.1e-30 105.5 1.8 2.8e-29 102.4 1.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX17812.1 - 0.00085 19.4 0.1 0.0033 17.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1800 PF08811.11 GAX17816.1 - 1.5e-46 159.4 0.0 3.1e-29 102.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX17816.1 - 1.2e-30 106.9 0.9 1.1e-29 103.8 0.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) DUF1800 PF08811.11 GAX17817.1 - 1e-48 166.5 0.0 1e-28 100.6 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX17817.1 - 5.2e-28 98.2 1.8 3.3e-27 95.5 1.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX17817.1 - 0.019 15.1 0.0 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain VIR_N PF15912.5 GAX17819.1 - 0.2 11.2 7.3 0.2 11.3 7.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal SelP_N PF04592.14 GAX17819.1 - 3.1 7.1 16.4 3.9 6.8 16.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FPL PF09758.9 GAX17820.1 - 3.8e-24 85.4 0.8 1.2e-23 83.7 0.8 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein DUF1800 PF08811.11 GAX17821.1 - 3.4e-42 145.0 0.0 4.4e-26 91.9 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX17821.1 - 6e-32 111.2 0.1 3e-31 108.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX17821.1 - 0.003 17.7 0.0 0.0096 16.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2255 PF10012.9 GAX17821.1 - 0.13 12.4 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Pet191_N PF10203.9 GAX17823.1 - 2.9e-17 62.7 2.8 3.2e-17 62.6 2.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DHHC PF01529.20 GAX17824.1 - 2.1e-26 92.6 3.8 2.1e-26 92.6 3.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3826 PF12875.7 GAX17825.1 - 0.0094 16.1 1.1 0.0094 16.1 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3826) RNase_H2_suC PF08615.11 GAX17825.1 - 0.0095 16.1 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PBP1_TM PF14812.6 GAX17825.1 - 0.22 11.9 22.2 2 8.8 8.9 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_Rpc4 PF05132.14 GAX17825.1 - 0.55 10.7 4.8 2.1 8.7 2.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM176 PF14851.6 GAX17825.1 - 0.78 9.4 13.5 0.25 11.0 2.1 2.5 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 GAX17825.1 - 2.4 8.2 13.3 0.15 12.1 1.9 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.11 GAX17825.1 - 3.2 5.7 9.1 2.9 5.9 1.3 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PTPRCAP PF15713.5 GAX17825.1 - 3.4 7.9 14.5 3.9 7.7 4.8 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 GAX17825.1 - 5.6 4.9 23.1 3 5.8 6.7 2.2 2 0 0 2 2 2 0 DNA polymerase phi NOA36 PF06524.12 GAX17825.1 - 5.6 6.2 23.1 0.068 12.5 5.9 2.2 2 0 0 2 2 2 0 NOA36 protein CPSF100_C PF13299.6 GAX17825.1 - 7.2 6.8 8.7 5.4 7.2 3.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Spt5_N PF11942.8 GAX17825.1 - 8.2 7.5 25.5 1.2 10.2 9.4 2.8 3 0 0 3 3 2 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 GAX17825.1 - 8.6 6.8 26.8 0.61 10.5 9.7 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RINGv PF12906.7 GAX17826.1 - 2.1e-11 43.8 7.9 4.2e-11 42.8 7.9 1.5 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 GAX17826.1 - 2.2e-09 37.6 0.0 8.5e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAX17826.1 - 5.1e-05 23.5 0.0 0.00017 21.8 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain EF-hand_7 PF13499.6 GAX17826.1 - 0.1 13.1 0.0 1 9.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-RING_2 PF13639.6 GAX17826.1 - 0.55 10.6 8.6 12 6.4 9.7 2.3 1 1 1 2 2 2 0 Ring finger domain FANCL_C PF11793.8 GAX17826.1 - 2.9 8.1 9.2 1.7 8.9 7.3 1.6 2 0 0 2 2 2 0 FANCL C-terminal domain zf-MYND PF01753.18 GAX17827.1 - 4.4e-09 36.3 16.9 9.3e-09 35.2 16.9 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 GAX17827.1 - 1.4 9.1 12.3 1.5 9.0 10.2 2.2 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 tRNA-synt_1d PF00750.19 GAX17828.1 - 8.7e-124 413.0 0.0 1.5e-123 412.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAX17828.1 - 2.1e-29 102.1 0.0 5.1e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAX17828.1 - 3.5e-18 66.0 0.2 1.7e-17 63.8 0.1 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 GAX17828.1 - 9.5e-05 21.9 0.0 0.00026 20.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 GAX17828.1 - 0.0018 16.6 0.2 0.034 12.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAX17828.1 - 0.054 12.2 0.1 0.088 11.5 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) RsmJ PF04378.13 GAX17829.1 - 3.5e-21 75.6 0.0 6.1e-21 74.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ TB2_DP1_HVA22 PF03134.19 GAX17830.1 - 2.1e-25 88.4 2.2 2.1e-25 88.4 2.2 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family CxxCxxCC PF03692.15 GAX17831.1 - 0.042 14.5 3.9 0.11 13.2 3.9 1.7 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain FAM176 PF14851.6 GAX17831.1 - 0.18 11.5 1.2 0.29 10.8 1.2 1.4 1 0 0 1 1 1 0 FAM176 family CxC6 PF18721.1 GAX17831.1 - 0.54 10.6 9.6 0.1 12.9 5.3 2.0 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases SUI1 PF01253.22 GAX17832.1 - 4.9e-25 87.9 1.7 5.9e-25 87.6 1.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Hydrophob_seed PF14547.6 GAX17832.1 - 0.023 14.9 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Hydrophobic seed protein Dus PF01207.17 GAX17832.1 - 0.069 12.2 0.2 0.1 11.6 0.2 1.4 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) UCH PF00443.29 GAX17834.1 - 1.4e-69 234.5 0.4 1.4e-69 234.5 0.4 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX17834.1 - 2.6e-15 56.8 3.0 9.9e-15 54.9 0.3 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PriX PF18689.1 GAX17834.1 - 0.13 12.6 0.1 6.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Primase X FYVE_2 PF02318.16 GAX17834.1 - 0.55 10.5 4.2 1.3 9.3 4.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger CEBP_ZZ PF16366.5 GAX17834.1 - 0.56 10.5 0.0 0.56 10.5 0.0 3.0 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Tetraspanin PF00335.20 GAX17836.1 - 0.0021 17.8 0.4 0.0088 15.8 0.0 2.1 1 1 1 2 2 2 1 Tetraspanin family DUF4229 PF14012.6 GAX17836.1 - 0.02 15.0 0.2 0.02 15.0 0.2 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) HTH_Tnp_ISL3 PF13542.6 GAX17836.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 RNF111_N PF15303.6 GAX17837.1 - 0.062 13.1 0.3 0.067 12.9 0.3 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus PIRT PF15099.6 GAX17838.1 - 0.07 12.7 2.7 0.52 9.9 2.7 2.2 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3953 PF13129.6 GAX17838.1 - 0.077 12.8 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) DUF4690 PF15756.5 GAX17838.1 - 0.74 10.5 4.1 1.4 9.6 4.1 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage MMU163 PF17119.5 GAX17839.1 - 0.09 11.9 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Xan_ur_permease PF00860.20 GAX17840.1 - 1.4e-21 76.7 24.9 2.8e-11 42.8 7.8 2.7 2 1 0 2 2 2 2 Permease family DUF5464 PF17552.2 GAX17840.1 - 0.0047 17.2 0.1 0.069 13.4 0.0 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5464) Wzy_C PF04932.15 GAX17840.1 - 0.068 12.8 10.8 0.13 11.9 0.6 2.7 2 0 0 2 2 2 0 O-Antigen ligase MFS_MOT1 PF16983.5 GAX17840.1 - 0.084 13.3 17.2 0.25 11.7 2.4 3.1 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Pyr_redox_2 PF07992.14 GAX17842.1 - 1.5e-40 139.3 0.0 1.9e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX17842.1 - 7.9e-11 42.4 1.9 3.1e-10 40.5 0.8 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.6 GAX17842.1 - 0.032 13.8 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Dynactin_p22 PF07426.11 GAX17843.1 - 0.0049 16.7 8.2 0.017 15.0 8.2 2.1 1 1 0 1 1 1 1 Dynactin subunit p22 RNF220 PF15926.5 GAX17843.1 - 0.073 12.7 0.3 0.073 12.7 0.3 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 TPR_7 PF13176.6 GAX17844.1 - 0.13 12.4 0.3 12 6.2 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TMEM43 PF07787.12 GAX17846.1 - 9e-54 182.5 0.1 1.7e-53 181.6 0.0 1.5 2 0 0 2 2 2 1 Transmembrane protein 43 OAD_gamma PF04277.13 GAX17846.1 - 0.65 10.6 2.5 19 6.0 0.4 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Chitin_synth_2 PF03142.15 GAX17846.1 - 2.3 6.7 4.3 3.4 6.2 4.3 1.1 1 0 0 1 1 1 0 Chitin synthase DUF2025 PF09634.10 GAX17849.1 - 0.051 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) DUF1800 PF08811.11 GAX17851.1 - 1.8e-40 139.3 0.0 1.3e-23 83.7 0.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX17851.1 - 6.9e-34 117.6 0.0 1.1e-33 116.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX17851.1 - 0.002 18.2 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEP PF00610.21 GAX17851.1 - 0.19 11.8 0.4 0.64 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) 2-Hacid_dh_C PF02826.19 GAX17852.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Njmu-R1 PF15053.6 GAX17853.1 - 0.063 12.4 0.3 0.09 11.9 0.3 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family MLANA PF14991.6 GAX17854.1 - 0.0023 18.2 0.4 0.0052 17.1 0.4 1.6 1 0 0 1 1 1 1 Protein melan-A FAM76 PF16046.5 GAX17854.1 - 0.0074 15.7 5.4 0.011 15.2 5.4 1.1 1 0 0 1 1 1 1 FAM76 protein V_ATPase_I PF01496.19 GAX17854.1 - 0.026 12.5 0.3 0.032 12.2 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EphA2_TM PF14575.6 GAX17854.1 - 0.042 14.7 0.0 0.078 13.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 GAX17854.1 - 0.045 14.0 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4446 PF14584.6 GAX17854.1 - 0.048 13.7 0.6 0.087 12.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CLN3 PF02487.17 GAX17854.1 - 0.068 12.2 0.5 0.095 11.7 0.5 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4330 PF14221.6 GAX17854.1 - 0.086 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Anoctamin PF04547.12 GAX17854.1 - 0.15 10.8 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Glyco_hydro_67C PF07477.12 GAX17854.1 - 0.16 11.5 1.3 0.25 10.9 1.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus TMEM51 PF15345.6 GAX17854.1 - 0.19 11.6 4.0 0.44 10.4 4.0 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 Vpu PF00558.19 GAX17854.1 - 6.6 6.6 11.2 0.092 12.5 3.1 2.0 2 0 0 2 2 2 0 Vpu protein O-FucT PF10250.9 GAX17855.1 - 0.041 13.6 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase CEP76-C2 PF15627.6 GAX17855.1 - 0.097 12.2 0.1 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 CEP76 C2 domain Thioredoxin PF00085.20 GAX17856.1 - 4.2e-22 78.1 0.0 5.4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 GAX17856.1 - 2e-06 27.7 0.0 7.3e-06 25.9 0.0 1.7 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 GAX17856.1 - 5.2e-06 26.6 0.0 9.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX17856.1 - 2.5e-05 24.5 0.0 0.0058 16.9 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 GAX17856.1 - 6.8e-05 22.6 0.0 9.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 GAX17856.1 - 0.00021 21.7 0.1 0.002 18.6 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GAX17856.1 - 0.0026 17.2 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 GAX17856.1 - 0.0088 16.0 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAX17856.1 - 0.046 13.5 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 GAX17856.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 GAX17856.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain adh_short_C2 PF13561.6 GAX17857.1 - 8.3e-55 185.9 2.4 7.2e-54 182.8 2.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX17857.1 - 9.4e-49 165.5 0.5 1.2e-48 165.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX17857.1 - 4.2e-09 36.6 0.3 6.5e-09 35.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX17857.1 - 5.1e-07 29.4 0.1 1.3e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAX17857.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAX17857.1 - 0.037 13.4 0.1 0.077 12.4 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAX17857.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Lactonase PF10282.9 GAX17858.1 - 1.3e-62 212.1 0.0 1.6e-61 208.5 0.0 2.1 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller AhpC-TSA PF00578.21 GAX17859.1 - 1e-05 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX17859.1 - 0.00071 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin YqzH PF14164.6 GAX17859.1 - 0.34 11.0 1.4 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 YqzH-like protein Bestrophin PF01062.21 GAX17860.1 - 4.4e-29 101.8 1.2 6.2e-29 101.3 1.2 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel LRR_8 PF13855.6 GAX17864.1 - 6e-27 93.2 32.9 1.3e-06 28.0 0.3 6.5 4 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX17864.1 - 3.8e-24 84.4 35.9 2.1e-05 24.8 0.0 8.6 5 2 5 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX17864.1 - 3.3e-12 45.2 19.5 0.17 12.5 0.0 10.1 10 2 1 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.6 GAX17864.1 - 8.3e-07 28.6 28.9 1.6 9.0 0.0 10.6 11 0 0 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.6 GAX17864.1 - 2.6 7.5 10.5 6.5 6.2 1.3 3.6 2 1 2 4 4 4 0 Leucine-rich repeat TPR_12 PF13424.6 GAX17865.1 - 1.9e-31 108.2 28.1 5e-15 55.5 2.5 4.3 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17865.1 - 1.6e-28 97.8 16.3 1.9e-08 33.9 0.1 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17865.1 - 2.6e-25 87.2 6.1 2.5e-06 27.0 0.0 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17865.1 - 8.9e-23 78.5 9.8 3.6e-05 23.6 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX17865.1 - 5.6e-16 57.3 2.4 0.00028 20.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17865.1 - 8.2e-11 41.2 9.7 0.03 14.3 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17865.1 - 2.1e-09 37.4 8.0 0.13 13.2 0.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX17865.1 - 5.8e-09 35.8 25.3 3.9e-06 26.5 12.7 2.2 1 1 2 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 GAX17865.1 - 1.8e-07 31.3 8.4 2.1 9.2 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX17865.1 - 3.1e-07 30.9 12.3 0.00013 22.5 0.1 4.7 2 2 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX17865.1 - 1.2e-05 24.9 13.1 0.0046 16.6 0.3 5.4 6 1 1 7 7 7 2 TPR repeat TPR_19 PF14559.6 GAX17865.1 - 5.7e-05 23.5 9.9 0.027 15.0 0.2 3.9 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_4 PF07721.14 GAX17865.1 - 9.6e-05 22.7 15.0 0.26 12.0 0.1 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAX17865.1 - 0.00049 20.3 5.1 3.7 8.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 GAX17865.1 - 0.0011 18.5 1.7 0.99 8.8 0.0 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 GAX17865.1 - 0.0025 17.9 0.2 9.2 6.4 0.0 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 GAX17865.1 - 0.0025 17.9 4.2 0.0046 17.1 0.0 3.2 2 2 1 3 3 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX17865.1 - 0.0075 16.3 6.2 1.7 8.8 0.1 4.4 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 GAX17865.1 - 0.016 14.9 1.3 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 GAX17865.1 - 0.03 14.4 0.5 21 5.3 0.0 3.9 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 GAX17865.1 - 0.11 12.8 0.0 0.41 11.0 0.0 2.1 1 0 0 1 1 1 0 PPR repeat TPR_20 PF14561.6 GAX17865.1 - 0.13 12.6 11.5 1.1 9.6 0.1 4.9 3 3 2 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAX17865.1 - 0.21 11.6 0.7 48 4.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX17865.1 - 0.27 11.5 3.2 6 7.2 0.0 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Pro_isomerase PF00160.21 GAX17866.1 - 1.8e-36 125.8 0.0 2.1e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Helicase_C PF00271.31 GAX17867.1 - 5.8e-32 110.3 0.3 3.7e-31 107.7 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX17867.1 - 3.5e-21 75.8 0.0 7.1e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 GAX17867.1 - 0.0048 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.25 GAX17867.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) SNARE_assoc PF09335.11 GAX17868.1 - 1.1e-16 61.4 3.3 2.9e-16 60.1 3.3 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF4235 PF14019.6 GAX17868.1 - 0.38 10.9 0.0 0.38 10.9 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF4235) Metallophos PF00149.28 GAX17871.1 - 4.2e-08 33.9 3.7 7.3e-08 33.1 3.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 GAX17871.1 - 0.0044 17.2 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain HSF_DNA-bind PF00447.17 GAX17872.1 - 1e-16 61.3 0.1 1.9e-16 60.5 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding LRR_8 PF13855.6 GAX17873.1 - 7.8e-33 112.0 45.2 3e-11 42.9 0.6 6.8 5 1 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GAX17873.1 - 6.2e-23 80.5 47.9 0.00013 22.2 2.2 8.6 2 2 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX17873.1 - 3.2e-05 23.9 40.5 0.23 12.2 0.4 11.9 14 0 0 14 14 14 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX17873.1 - 7.9e-05 22.4 34.6 0.048 13.7 0.1 10.2 12 0 0 12 12 12 3 Leucine Rich repeat LAP1C PF05609.12 GAX17873.1 - 0.0074 15.4 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) LRR_9 PF14580.6 GAX17873.1 - 0.016 14.7 13.2 0.49 9.9 0.3 4.4 1 1 3 5 5 5 0 Leucine-rich repeat Tom7 PF08038.12 GAX17873.1 - 1 9.1 2.9 0.59 9.8 0.3 1.9 2 0 0 2 2 2 0 TOM7 family HNH_3 PF13392.6 GAX17873.1 - 1.2 8.9 3.8 21 4.9 0.7 3.3 3 0 0 3 3 3 0 HNH endonuclease EMP70 PF02990.16 GAX17874.1 - 1.8e-183 610.9 6.9 1.8e-183 610.9 6.9 1.6 1 1 1 2 2 2 1 Endomembrane protein 70 DUF4381 PF14316.6 GAX17874.1 - 0.85 9.9 0.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Phage_holin_2_1 PF04971.12 GAX17874.1 - 2.1 8.4 7.8 1 9.4 1.5 2.7 2 0 0 2 2 2 0 Bacteriophage P21 holin S MCM PF00493.23 GAX17875.1 - 1.8e-98 328.1 0.0 2.7e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX17875.1 - 1.1e-34 119.0 0.0 1.9e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX17875.1 - 1.9e-23 82.7 0.8 4.5e-23 81.5 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAX17875.1 - 5.9e-18 65.4 0.6 2.8e-17 63.2 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAX17875.1 - 5.6e-09 35.7 0.6 7e-07 28.8 0.0 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 GAX17875.1 - 2.3e-07 31.2 48.5 2.3e-07 31.2 48.5 4.6 3 1 0 4 4 4 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 GAX17875.1 - 4.1e-07 30.1 0.0 1.8e-06 28.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAX17875.1 - 0.00044 20.1 0.0 0.0038 17.1 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 GAX17875.1 - 0.0069 16.2 0.0 0.075 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 GAX17875.1 - 0.027 14.2 0.1 0.22 11.2 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 GAX17875.1 - 0.09 13.2 0.0 0.46 10.9 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Snf7 PF03357.21 GAX17876.1 - 1.4e-30 106.1 4.4 1.5e-30 106.0 4.4 1.0 1 0 0 1 1 1 1 Snf7 HBM PF16591.5 GAX17876.1 - 0.00069 19.1 0.5 0.00082 18.9 0.5 1.1 1 0 0 1 1 1 1 Helical bimodular sensor domain Latarcin PF10279.9 GAX17876.1 - 0.8 10.2 5.3 5.6 7.4 5.5 2.2 1 1 1 2 2 2 0 Latarcin precursor Ion_trans_2 PF07885.16 GAX17877.1 - 2.1e-28 98.1 23.0 2.7e-14 52.9 7.7 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 GAX17877.1 - 1.1e-06 28.1 1.8 0.004 16.4 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein DUF3246 PF11596.8 GAX17877.1 - 8.9 5.7 10.2 1.7 8.0 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF4780 PF16012.5 GAX17878.1 - 0.05 13.1 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) RcbX PF02341.15 GAX17878.1 - 0.08 13.2 0.2 2 8.7 0.0 2.7 3 0 0 3 3 3 0 RbcX protein Peptidase_M16_C PF05193.21 GAX17879.1 - 2.8e-37 128.5 0.0 8.5e-20 71.5 0.0 3.2 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAX17879.1 - 6.2e-15 55.5 0.0 1.5e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sdh_cyt PF01127.22 GAX17880.1 - 8.1e-16 58.2 0.3 1.1e-15 57.7 0.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit COX6C PF02937.15 GAX17881.1 - 0.00079 19.5 0.1 0.0011 19.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc Rotamase PF00639.21 GAX17882.1 - 5.9e-09 36.8 0.0 8.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX17882.1 - 7.1e-07 29.8 0.0 1e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Flg_hook PF02120.16 GAX17883.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK EF-hand_7 PF13499.6 GAX17884.1 - 1.5e-09 38.1 2.2 0.0011 19.4 0.4 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX17884.1 - 1.3e-07 31.0 5.7 0.017 15.0 0.0 4.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 GAX17884.1 - 9.2e-07 28.6 0.3 0.00037 20.3 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX17884.1 - 2.6e-06 26.6 7.3 0.27 10.9 0.0 4.7 5 0 0 5 5 5 2 EF hand Glyco_trans_1_2 PF13524.6 GAX17884.1 - 0.0014 19.0 0.1 0.0034 17.7 0.1 1.7 1 1 1 2 2 2 1 Glycosyl transferases group 1 EF-hand_9 PF14658.6 GAX17884.1 - 0.0019 18.5 0.0 0.28 11.5 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain Smoothelin PF12510.8 GAX17884.1 - 0.039 14.0 1.8 0.11 12.6 0.4 2.3 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein EF-hand_like PF09279.11 GAX17884.1 - 0.042 14.3 0.7 0.8 10.2 0.0 2.7 1 1 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like E3_UFM1_ligase PF09743.9 GAX17884.1 - 0.056 13.1 0.0 0.082 12.5 0.0 1.4 1 1 0 1 1 1 0 E3 UFM1-protein ligase 1 EFhand_Ca_insen PF08726.10 GAX17884.1 - 0.063 13.4 0.3 0.35 11.0 0.1 2.3 2 1 1 3 3 3 0 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 GAX17884.1 - 0.089 12.3 2.0 11 5.7 0.0 3.6 3 0 0 3 3 3 0 EF hand MMADHC PF10229.9 GAX17885.1 - 6.3e-27 95.0 0.0 7.2e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Acyl-CoA_dh_1 PF00441.24 GAX17886.1 - 8.5e-31 107.2 1.3 1.7e-30 106.2 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX17886.1 - 3e-27 95.5 0.0 5.1e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAX17886.1 - 4.6e-21 74.8 0.0 7.7e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAX17886.1 - 2e-07 31.4 0.2 4.3e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain VWA_2 PF13519.6 GAX17887.1 - 1.2e-14 54.9 0.1 2.4e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAX17887.1 - 1.4e-12 48.2 0.1 2.3e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX17887.1 - 2.8e-06 27.3 0.0 5.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GAX17887.1 - 0.00056 19.4 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 GAX17887.1 - 0.0035 17.5 0.1 0.006 16.7 0.1 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DrsE PF02635.15 GAX17887.1 - 0.087 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 DsrE/DsrF-like family DUF2201 PF09967.9 GAX17887.1 - 0.097 12.8 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 VWA-like domain (DUF2201) Zn-ribbon_8 PF09723.10 GAX17887.1 - 8.4 6.6 8.7 22 5.3 2.7 3.1 2 0 0 2 2 2 0 Zinc ribbon domain CS PF04969.16 GAX17889.1 - 5.3e-12 46.6 0.1 1.3e-11 45.3 0.1 1.7 2 0 0 2 2 2 1 CS domain Ank_3 PF13606.6 GAX17890.1 - 5.2e-08 32.6 0.0 0.031 14.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAX17890.1 - 3.1e-07 30.8 0.1 9.9e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX17890.1 - 1.2e-05 25.8 0.0 2.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX17890.1 - 0.0043 17.3 0.1 0.14 12.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) F-box PF00646.33 GAX17890.1 - 0.017 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 F-box domain Ank PF00023.30 GAX17890.1 - 0.03 14.8 0.0 2.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat DUF5305 PF17231.2 GAX17890.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) dCMP_cyt_deam_1 PF00383.23 GAX17891.1 - 1.5e-23 82.6 0.3 4.4e-23 81.1 0.3 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX17891.1 - 1.9e-18 66.5 0.0 1.5e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 GAX17891.1 - 0.00024 21.2 0.2 0.13 12.3 0.1 2.2 2 0 0 2 2 2 2 Bd3614-like deaminase PRA-CH PF01502.18 GAX17896.1 - 6.8e-25 86.7 0.1 1.3e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 GAX17896.1 - 9.7e-14 51.6 5.4 9.8e-14 51.6 3.5 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 GAX17896.1 - 0.00018 21.6 0.7 0.00018 21.6 0.7 2.2 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 GAX17896.1 - 0.016 15.5 0.1 0.037 14.3 0.1 1.6 1 0 0 1 1 1 0 MazG-like family Ribosomal_L14e PF01929.17 GAX17897.1 - 6.7e-31 106.6 6.2 9.8e-31 106.1 6.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 GAX17897.1 - 0.024 14.6 0.1 0.084 12.9 0.1 1.9 1 1 0 1 1 1 0 KOW motif Glyco_hydro_32N PF00251.20 GAX17898.1 - 3.2e-05 23.7 0.1 0.00075 19.1 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Usher_TcfC PF17271.2 GAX17898.1 - 0.0071 15.2 0.2 0.014 14.2 0.2 1.4 1 0 0 1 1 1 1 TcfC Usher-like barrel domain Vps35 PF03635.17 GAX17899.1 - 2.1e-214 714.2 0.0 2.4e-214 714.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Chlamy_scaf PF09675.10 GAX17899.1 - 0.11 12.9 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) AAA PF00004.29 GAX17900.1 - 7.9e-41 139.6 0.1 3.9e-40 137.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX17900.1 - 5.6e-11 42.1 0.4 1e-10 41.2 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GAX17900.1 - 1.9e-08 34.1 0.0 4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 GAX17900.1 - 9.8e-06 25.9 0.3 0.004 17.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX17900.1 - 2.2e-05 24.5 0.1 0.00014 21.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX17900.1 - 4.1e-05 22.9 0.0 7.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 GAX17900.1 - 4.3e-05 23.7 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAX17900.1 - 6.3e-05 23.4 0.2 0.0015 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAX17900.1 - 0.00094 19.0 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 GAX17900.1 - 0.0021 17.4 0.1 0.3 10.4 0.1 2.4 1 1 1 2 2 2 1 KaiC IstB_IS21 PF01695.17 GAX17900.1 - 0.014 15.2 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 GAX17900.1 - 0.022 15.2 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 GAX17900.1 - 0.024 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 GAX17900.1 - 0.024 14.5 0.0 0.083 12.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAX17900.1 - 0.037 14.2 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAX17900.1 - 0.039 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 GAX17900.1 - 0.045 13.5 0.1 0.16 11.7 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 GAX17900.1 - 0.048 13.9 0.3 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAX17900.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAX17900.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GAX17900.1 - 0.096 12.6 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 GAX17900.1 - 0.12 11.8 0.2 0.29 10.6 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 GAX17900.1 - 0.13 11.8 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region CLP_protease PF00574.23 GAX17901.1 - 4e-48 163.7 0.1 8.6e-48 162.6 0.1 1.5 1 1 0 1 1 1 1 Clp protease Mt_ATP-synt_B PF05405.14 GAX17902.1 - 4.4e-16 58.9 3.5 4.4e-16 58.9 3.5 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sde2_N_Ubi PF13019.6 GAX17902.1 - 0.032 14.0 0.1 0.084 12.7 0.1 1.8 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain DUF2373 PF10180.9 GAX17903.1 - 1.7e-22 79.0 1.6 3.9e-22 77.9 1.6 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) CCT PF06203.14 GAX17904.1 - 1.2e-17 63.6 10.7 2.3e-17 62.7 10.7 1.5 1 0 0 1 1 1 1 CCT motif GPR15L PF15854.5 GAX17904.1 - 0.51 10.6 1.9 2.8 8.2 0.0 2.2 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 GTP_EFTU PF00009.27 GAX17905.1 - 7e-50 169.3 0.1 1.3e-49 168.4 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAX17905.1 - 9.8e-40 135.3 0.2 3.1e-39 133.8 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAX17905.1 - 6.8e-12 45.6 0.2 2.3e-11 43.9 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX17905.1 - 1.8e-05 24.8 0.1 0.00013 22.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAX17905.1 - 0.0091 15.9 0.1 0.03 14.2 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.10 GAX17905.1 - 0.026 14.0 0.2 0.15 11.5 0.1 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 GAX17905.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain adh_short_C2 PF13561.6 GAX17907.1 - 2e-50 171.5 0.2 2.5e-50 171.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX17907.1 - 2.2e-44 151.2 0.0 2.8e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX17907.1 - 2.8e-06 27.4 0.1 4.1e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX17907.1 - 0.00074 19.0 0.5 0.8 9.1 0.2 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAX17907.1 - 0.0011 19.5 0.1 0.0032 18.0 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 GAX17907.1 - 0.0023 17.9 0.3 0.0049 16.8 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 GAX17907.1 - 0.094 12.0 2.7 0.51 9.6 0.1 2.9 3 1 1 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 GAX17907.1 - 0.1 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain kleA_kleC PF17383.2 GAX17909.1 - 0.13 12.6 1.2 7.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Ion_trans PF00520.31 GAX17910.1 - 8.5e-37 126.7 25.5 1.2e-36 126.3 25.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GAX17910.1 - 3.8e-07 29.1 17.7 0.00052 18.8 1.8 2.2 1 1 1 2 2 2 2 Polycystin cation channel PDCD2_C PF04194.13 GAX17911.1 - 6.2e-35 120.8 10.2 5.2e-34 117.8 8.2 2.5 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain CpXC PF14353.6 GAX17911.1 - 0.29 11.2 2.1 4 7.5 0.0 2.6 2 0 0 2 2 2 0 CpXC protein DUF3140 PF11338.8 GAX17912.1 - 0.022 15.2 0.1 0.026 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Zn_clus PF00172.18 GAX17913.1 - 4.8e-09 36.2 7.7 1.1e-08 35.0 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_34 PF05637.12 GAX17914.1 - 1.3e-25 90.5 0.9 9.2e-14 51.7 0.3 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GAX17914.1 - 4.4e-09 36.2 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 SQS_PSY PF00494.19 GAX17915.1 - 1.3e-37 129.7 3.9 1.6e-37 129.4 3.9 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Chloroa_b-bind PF00504.21 GAX17916.1 - 9.5e-37 127.0 0.2 1.2e-36 126.7 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF1664 PF07889.12 GAX17917.1 - 0.26 11.3 9.4 0.085 12.9 1.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) kleA_kleC PF17383.2 GAX17917.1 - 0.46 10.8 10.1 0.65 10.4 0.5 3.0 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A KELK PF15796.5 GAX17917.1 - 0.67 10.4 22.0 1.3 9.5 5.4 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LON_substr_bdg PF02190.16 GAX17918.1 - 8.5e-07 29.0 0.3 2.3e-06 27.6 0.3 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF2378 PF09536.10 GAX17918.1 - 0.16 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) Glyco_transf_90 PF05686.12 GAX17919.1 - 9.3e-18 64.3 1.3 1.5e-17 63.6 1.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAX17919.1 - 0.00029 21.2 0.0 0.00067 20.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.12 GAX17920.1 - 1.1e-20 73.9 0.4 2.2e-20 73.0 0.4 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAX17920.1 - 0.00043 20.6 0.0 0.00089 19.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase_C PF00433.24 GAX17921.1 - 0.02 15.6 0.4 0.037 14.7 0.4 1.4 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF4519 PF15012.6 GAX17921.1 - 0.039 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) TLD PF07534.16 GAX17922.1 - 0.00039 20.7 0.0 0.00055 20.2 0.0 1.2 1 0 0 1 1 1 1 TLD Coatomer_WDAD PF04053.14 GAX17924.1 - 4.2e-136 454.5 0.0 1.5e-135 452.7 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAX17924.1 - 1.8e-39 133.0 6.1 3.3e-08 34.1 0.1 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17924.1 - 1.7e-07 31.4 0.1 1.5 9.2 0.0 5.7 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX17924.1 - 0.00018 21.5 0.0 0.53 10.1 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAX17924.1 - 0.041 12.5 0.1 9 4.8 0.0 3.7 3 2 1 4 4 4 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAX17924.1 - 0.12 11.1 0.5 4.8 5.8 0.1 3.2 2 2 1 3 3 3 0 Nup133 N terminal like MitMem_reg PF13012.6 GAX17926.1 - 1.9e-08 34.7 0.2 4.1e-08 33.6 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAX17926.1 - 5.1e-05 23.2 0.1 0.0024 17.8 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Catalase-rel PF06628.12 GAX17927.1 - 0.0043 17.2 0.4 0.011 16.0 0.4 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF423 PF04241.15 GAX17929.1 - 0.017 15.3 0.5 0.27 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF423) E1-E2_ATPase PF00122.20 GAX17930.1 - 6e-44 149.7 0.2 6e-44 149.7 0.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAX17930.1 - 5.7e-25 88.8 0.0 1e-24 88.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAX17930.1 - 1.9e-05 25.0 7.1 0.14 12.6 0.3 3.8 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAX17930.1 - 0.004 16.9 1.5 0.028 14.2 0.9 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3906 PF13046.6 GAX17930.1 - 0.06 13.5 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) WD40 PF00400.32 GAX17931.1 - 7.2e-43 143.7 5.5 1.4e-08 35.2 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17931.1 - 2.1e-17 63.2 0.2 0.014 15.6 0.0 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX17931.1 - 8.6e-09 34.6 4.8 0.002 16.8 0.0 4.6 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX17931.1 - 2.1e-07 30.2 3.6 0.0002 20.4 0.2 3.6 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 GAX17931.1 - 4.5e-05 22.0 0.0 0.11 10.7 0.0 2.9 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 GAX17931.1 - 9.7e-05 22.3 0.0 0.0018 18.2 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 GAX17931.1 - 0.0033 16.5 0.1 0.13 11.2 0.0 2.8 1 1 3 4 4 4 1 VID27 C-terminal WD40-like domain WD40_like PF17005.5 GAX17931.1 - 0.0096 15.3 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain PALB2_WD40 PF16756.5 GAX17931.1 - 0.015 14.3 0.4 1.9 7.3 0.0 3.0 1 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 GAX17931.1 - 0.015 14.9 4.6 0.37 10.3 4.6 2.5 1 1 0 1 1 1 0 PQQ-like domain Cytochrom_D1 PF02239.16 GAX17931.1 - 0.015 13.8 0.1 2.3 6.7 0.0 2.2 1 1 0 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.6 GAX17931.1 - 0.039 13.3 0.9 11 5.2 0.0 3.0 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PPR_1 PF12854.7 GAX17932.1 - 2.5e-49 164.7 0.4 0.00018 21.1 0.0 13.6 12 3 0 12 12 12 11 PPR repeat PPR_2 PF13041.6 GAX17932.1 - 6.5e-45 151.1 8.7 1.6e-06 28.2 0.1 10.4 6 4 4 10 10 10 10 PPR repeat family PPR_3 PF13812.6 GAX17932.1 - 5.6e-30 103.2 0.0 3.4e-05 23.8 0.0 10.7 8 3 2 10 10 10 7 Pentatricopeptide repeat domain PPR PF01535.20 GAX17932.1 - 2.1e-19 68.4 20.3 0.54 10.6 0.0 14.4 12 4 1 13 13 13 5 PPR repeat PPR_long PF17177.4 GAX17932.1 - 6.5e-16 58.3 2.2 0.0033 16.8 0.1 5.4 1 1 3 5 5 5 5 Pentacotripeptide-repeat region of PRORP Glu-tRNAGln PF02686.15 GAX17932.1 - 0.15 12.4 0.0 5.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit TC1 PF15063.6 GAX17932.1 - 0.26 11.2 4.1 10 6.0 0.0 4.8 5 1 1 6 6 6 0 Thyroid cancer protein 1 OmpH PF03938.14 GAX17933.1 - 0.65 10.3 13.9 0.56 10.5 11.3 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FliJ PF02050.16 GAX17933.1 - 1 9.6 21.0 0.84 9.9 18.4 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.6 GAX17933.1 - 6.7 6.0 9.0 13 5.0 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_2 PF07727.14 GAX17934.1 - 3.5e-19 69.4 0.0 2.4e-18 66.7 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TSP_3 PF02412.18 GAX17937.1 - 0.00048 19.8 200.5 0.005 16.5 6.4 14.2 13 1 0 13 13 13 13 Thrombospondin type 3 repeat TSP_3 PF02412.18 GAX17938.1 - 0.0066 16.1 389.1 0.056 13.1 5.8 25.4 24 2 1 25 25 25 21 Thrombospondin type 3 repeat TSP_3 PF02412.18 GAX17939.1 - 2.6e-07 30.2 387.9 0.0043 16.7 7.1 25.6 24 2 1 25 25 25 22 Thrombospondin type 3 repeat Tam41_Mmp37 PF09139.11 GAX17940.1 - 1.3e-69 235.1 0.0 1.7e-60 205.2 0.0 2.0 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial CRAL_TRIO PF00650.20 GAX17941.1 - 7.1e-06 25.8 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain H_PPase PF03030.16 GAX17943.1 - 3.1e-258 858.8 31.5 3.1e-258 858.8 31.5 1.7 2 0 0 2 2 2 1 Inorganic H+ pyrophosphatase KbaA PF14089.6 GAX17943.1 - 0.058 13.2 0.1 0.18 11.6 0.1 2.0 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation PEPCK_ATP PF01293.20 GAX17946.1 - 3.5e-209 695.3 0.0 4.1e-209 695.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 GAX17946.1 - 0.096 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX17946.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain His_Phos_1 PF00300.22 GAX17947.1 - 7.5e-60 201.9 0.7 3e-24 85.8 0.0 5.1 3 1 2 5 5 5 4 Histidine phosphatase superfamily (branch 1) MAF_flag10 PF01973.18 GAX17947.1 - 0.094 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF115 Pyr_redox_2 PF07992.14 GAX17948.1 - 2e-53 181.6 1.3 2.8e-53 181.1 1.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX17948.1 - 2.2e-32 111.6 3.1 3.9e-32 110.8 1.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX17948.1 - 4.5e-16 59.2 4.8 4e-14 52.9 0.7 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX17948.1 - 1.8e-12 47.2 1.7 4.3e-12 45.9 1.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAX17948.1 - 0.00024 20.4 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 GAX17948.1 - 0.0011 18.4 0.2 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX17948.1 - 0.0014 17.8 2.8 0.026 13.6 1.8 2.5 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 GAX17948.1 - 0.09 11.5 0.8 0.82 8.3 0.4 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 GAX17948.1 - 0.098 12.9 0.9 0.25 11.6 0.9 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAX17948.1 - 0.21 10.6 3.6 0.26 10.3 0.8 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.24 GAX17948.1 - 3.3 7.2 7.0 0.13 11.8 0.7 1.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase DUF4441 PF14536.6 GAX17949.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) BrkDBD PF09607.10 GAX17950.1 - 0.045 13.5 1.3 0.36 10.6 0.1 2.3 2 0 0 2 2 2 0 Brinker DNA-binding domain zf-LYAR PF08790.11 GAX17950.1 - 0.067 13.1 1.0 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Alpha-amylase_N PF02903.14 GAX17950.1 - 0.077 13.2 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain MREG PF15812.5 GAX17950.1 - 0.84 9.9 4.7 0.58 10.4 1.1 1.9 1 1 1 2 2 2 0 Melanoregulin Pro_isomerase PF00160.21 GAX17951.1 - 5.3e-20 72.3 0.0 8.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4231 PF14015.6 GAX17951.1 - 0.087 13.3 0.1 0.2 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF92 PF01940.16 GAX17952.1 - 1.3e-42 145.9 4.2 1.8e-42 145.4 4.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Rrp15p PF07890.12 GAX17953.1 - 2e-26 92.9 4.6 2e-26 92.9 4.6 3.1 3 1 0 3 3 3 1 Rrp15p DUF469 PF04320.14 GAX17954.1 - 0.00072 20.4 0.6 1.8 9.5 0.2 2.8 2 0 0 2 2 2 2 Protein with unknown function (DUF469) ATG22 PF11700.8 GAX17955.1 - 3.2e-20 72.2 26.8 4.2e-18 65.2 26.8 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAX17955.1 - 3.6e-12 45.9 24.1 5.3e-12 45.3 24.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SPOUT_MTase PF02590.17 GAX17956.1 - 4.8e-32 111.1 0.0 6.5e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase ANAPC10 PF03256.16 GAX17958.1 - 4.7e-48 163.3 0.2 6.1e-48 162.9 0.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 GAX17958.1 - 1.9e-05 24.8 0.4 6.9e-05 23.0 0.2 1.9 2 0 0 2 2 2 1 F5/8 type C domain PI3K_1B_p101 PF10486.9 GAX17958.1 - 0.046 11.5 2.1 0.068 10.9 2.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit eIF-3c_N PF05470.12 GAX17958.1 - 0.14 10.5 0.6 0.14 10.4 0.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus GOLD_2 PF13897.6 GAX17958.1 - 0.15 12.6 0.8 0.34 11.4 0.8 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DNA_pol_phi PF04931.13 GAX17958.1 - 3.8 5.5 12.7 6.8 4.6 12.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2722 PF10846.8 GAX17958.1 - 5.9 5.7 7.2 45 2.8 8.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CENP-B_dimeris PF09026.10 GAX17958.1 - 7.2 7.1 24.9 18 5.8 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain WD40 PF00400.32 GAX17959.1 - 6.4e-27 93.3 28.5 1.2e-06 29.1 0.1 10.1 10 1 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX17959.1 - 8.1e-08 32.5 3.0 1.7 9.0 0.0 6.5 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain ATP-grasp_4 PF13535.6 GAX17963.1 - 1e-24 86.9 0.0 1.8e-11 43.9 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 GAX17963.1 - 4.5e-23 82.1 0.0 4.3e-11 42.9 0.0 2.9 2 2 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 GAX17963.1 - 2.1e-22 79.9 0.0 7.3e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_D2 PF02786.17 GAX17963.1 - 6.5e-10 38.9 0.0 0.00063 19.3 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 GAX17963.1 - 1.2e-07 31.5 0.0 0.019 14.7 0.0 4.1 4 1 0 4 4 4 2 ATP-grasp in the biosynthetic pathway with Ter operon LAL_C2 PF18603.1 GAX17963.1 - 3.6e-07 30.3 0.0 0.0026 17.9 0.0 2.9 2 0 0 2 2 2 2 L-amino acid ligase C-terminal domain 2 RimK PF08443.11 GAX17963.1 - 0.0059 16.2 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAX17963.1 - 0.031 13.8 0.0 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 GAX17964.1 - 2.3e-27 95.5 0.0 1.6e-12 47.3 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 GAX17964.1 - 1.9e-22 80.0 0.0 8.7e-10 38.9 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 GAX17964.1 - 1.6e-19 70.5 0.0 2.6e-08 33.9 0.0 3.6 2 2 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 GAX17964.1 - 2.7e-10 40.1 0.0 0.00054 19.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain LAL_C2 PF18603.1 GAX17964.1 - 2.2e-09 37.4 0.1 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 GAX17964.1 - 6.1e-08 32.5 0.0 0.057 13.2 0.0 4.7 3 2 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 GAX17964.1 - 0.012 15.3 0.0 4.2 6.9 0.0 2.8 3 1 0 3 3 3 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAX17964.1 - 0.021 14.4 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus DUF3185 PF11381.8 GAX17964.1 - 0.063 13.3 0.3 6.5 6.9 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Kunitz_BPTI PF00014.23 GAX17964.1 - 0.15 12.3 0.1 26 5.2 0.0 2.5 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Nuc_sug_transp PF04142.15 GAX17966.1 - 1.3e-05 24.6 0.5 2.5e-05 23.6 0.5 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 GAX17966.1 - 0.0063 15.8 0.3 0.0063 15.8 0.3 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 GAX17966.1 - 0.011 15.9 1.2 0.011 15.9 1.2 4.3 3 1 0 3 3 3 0 EamA-like transporter family CRT-like PF08627.10 GAX17966.1 - 0.012 14.6 11.9 0.038 12.9 0.3 3.0 3 0 0 3 3 3 0 CRT-like, chloroquine-resistance transporter-like Collectrin PF16959.5 GAX17966.1 - 0.012 15.3 0.4 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Renal amino acid transporter DUF4781 PF16013.5 GAX17966.1 - 0.07 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF2530 PF10745.9 GAX17966.1 - 0.17 12.2 1.5 0.53 10.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Amino_oxidase PF01593.24 GAX17967.1 - 8.7e-47 160.4 0.0 9e-37 127.4 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAX17967.1 - 5.1e-10 39.1 1.2 1.7e-05 24.2 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX17967.1 - 1e-08 35.3 0.0 2.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX17967.1 - 3e-07 29.9 0.0 1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX17967.1 - 1.7e-05 24.6 0.4 0.058 13.0 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX17967.1 - 0.00018 20.4 0.2 0.028 13.1 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 GAX17967.1 - 0.00019 21.4 1.5 0.027 14.5 0.0 2.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 GAX17967.1 - 0.00054 19.3 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAX17967.1 - 0.0017 17.5 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GAX17967.1 - 0.0019 17.3 0.0 0.038 13.1 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAX17967.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 GAX17967.1 - 0.22 12.1 0.2 2.3 8.8 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Amino_oxidase PF01593.24 GAX17968.1 - 7e-44 150.9 0.0 1.6e-33 116.7 0.0 2.1 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAX17968.1 - 9.1e-11 41.6 1.7 9.3e-06 25.1 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX17968.1 - 3.8e-08 33.4 0.0 8.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX17968.1 - 6.3e-06 25.6 1.7 0.00011 21.5 1.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX17968.1 - 0.00029 20.8 0.9 0.054 13.5 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 GAX17968.1 - 0.00059 18.6 0.5 0.037 12.7 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GAX17968.1 - 0.0016 17.7 0.1 0.0031 16.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAX17968.1 - 0.0018 17.4 0.0 0.023 13.8 0.0 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAX17968.1 - 0.0036 16.4 0.2 0.0066 15.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAX17968.1 - 0.015 14.5 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 GAX17968.1 - 0.016 14.8 2.4 0.073 12.6 0.4 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 GAX17968.1 - 0.021 15.4 0.1 1.3 9.7 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 GAX17968.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAX17968.1 - 0.19 11.0 0.4 1.2 8.4 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Abhydrolase_6 PF12697.7 GAX17969.1 - 3.1e-15 57.4 0.3 4.3e-15 56.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX17969.1 - 9.7e-13 47.9 0.0 3.5e-06 26.5 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX17969.1 - 3.9e-09 36.5 0.0 2.2e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 GAX17969.1 - 0.0044 16.6 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region LIDHydrolase PF10230.9 GAX17969.1 - 0.032 13.8 0.0 0.36 10.4 0.0 2.3 2 1 0 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 GAX17969.1 - 0.13 12.1 0.0 0.91 9.4 0.0 2.2 3 0 0 3 3 3 0 Serine hydrolase adh_short PF00106.25 GAX17970.1 - 1.6e-42 145.2 0.1 2.2e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX17970.1 - 5.7e-25 88.2 0.2 8.8e-25 87.6 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX17970.1 - 1.5e-11 44.5 0.3 2.4e-11 43.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX17970.1 - 0.014 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family EamA PF00892.20 GAX17971.1 - 3.1e-07 30.6 0.9 3.1e-07 30.6 0.9 3.5 2 1 1 3 3 3 1 EamA-like transporter family Mg_trans_NIPA PF05653.14 GAX17971.1 - 0.00014 21.0 16.5 0.00022 20.4 14.4 2.2 2 1 0 2 2 2 1 Magnesium transporter NIPA DUF4212 PF13937.6 GAX17971.1 - 0.04 14.3 0.9 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) PTR2 PF00854.21 GAX17972.1 - 2.8e-38 131.8 19.9 3.5e-24 85.4 5.5 2.1 2 0 0 2 2 2 2 POT family SDA1 PF05285.12 GAX17973.1 - 0.83 9.0 4.2 1.3 8.3 4.2 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GAX17973.1 - 1.5 8.4 4.4 2.3 7.7 4.4 1.3 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 GAX17973.1 - 2.4 6.2 12.2 3.4 5.7 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 GAX17973.1 - 2.8 7.0 8.0 4.2 6.4 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 GAX17973.1 - 5.1 6.3 8.6 9.3 5.5 8.6 1.3 1 0 0 1 1 1 0 NOA36 protein B56 PF01603.20 GAX17974.1 - 4e-172 572.9 0.0 4.8e-172 572.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Na_H_Exchanger PF00999.21 GAX17974.1 - 0.064 12.0 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Ank_2 PF12796.7 GAX17975.1 - 4.6e-15 56.0 0.0 1.1e-08 35.5 0.0 3.2 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX17975.1 - 4e-11 42.1 4.8 0.077 13.6 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAX17975.1 - 4e-09 36.6 3.5 0.00057 20.1 0.1 4.6 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX17975.1 - 5e-08 33.3 4.1 0.0037 17.8 0.0 4.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX17975.1 - 1.1e-06 28.7 6.2 0.63 10.6 0.1 5.4 5 0 0 5 5 5 2 Ankyrin repeat NTP_transf_3 PF12804.7 GAX17975.1 - 0.0036 17.7 0.7 0.0061 16.9 0.4 1.6 1 1 1 2 2 2 1 MobA-like NTP transferase domain 2-Hacid_dh_C PF02826.19 GAX17978.1 - 4.4e-41 140.2 0.0 6.3e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX17978.1 - 1.4e-13 50.7 0.0 1.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DEDD_Tnp_IS110 PF01548.17 GAX17978.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Transposase KR PF08659.10 GAX17978.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.6 1 1 0 1 1 1 0 KR domain XdhC_C PF13478.6 GAX17978.1 - 0.15 12.6 0.0 1.2 9.6 0.0 2.4 2 2 1 3 3 3 0 XdhC Rossmann domain zf-MYND PF01753.18 GAX17979.1 - 1e-09 38.3 16.2 1e-09 38.3 16.2 3.5 3 1 0 3 3 2 1 MYND finger TPR_12 PF13424.6 GAX17979.1 - 1.2e-08 35.1 0.5 0.0026 18.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17979.1 - 4.9e-05 23.0 0.5 0.92 9.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17979.1 - 7.1e-05 22.5 2.3 5.6 7.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17979.1 - 0.00026 20.9 5.0 2.3 8.6 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX17979.1 - 0.00031 21.3 1.6 0.67 10.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX17979.1 - 0.00045 20.1 0.0 0.089 12.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX17979.1 - 0.0013 19.2 5.5 1.1 10.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4919 PF16266.5 GAX17979.1 - 0.0014 18.6 0.2 0.0074 16.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) TPR_19 PF14559.6 GAX17979.1 - 0.003 18.0 1.5 1.8 9.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4 PF00097.25 GAX17979.1 - 0.0036 17.1 8.5 0.0036 17.1 8.5 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.6 GAX17979.1 - 0.005 17.5 0.4 11 6.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-RING_5 PF14634.6 GAX17979.1 - 0.0098 15.8 8.2 0.0098 15.8 8.2 2.8 3 0 0 3 3 3 1 zinc-RING finger domain TPR_8 PF13181.6 GAX17979.1 - 0.012 15.8 0.7 6.9 7.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 GAX17979.1 - 0.053 12.6 3.1 3.3 6.7 0.7 2.2 2 0 0 2 2 2 0 Spatacsin C-terminus DMRL_synthase PF00885.19 GAX17980.1 - 2.8e-50 169.8 0.0 3.7e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DBI_PRT PF02277.17 GAX17980.1 - 0.04 13.2 0.5 0.057 12.7 0.5 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase TIP49 PF06068.13 GAX17981.1 - 1.1e-140 468.8 0.0 1.4e-140 468.5 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAX17981.1 - 7.5e-23 80.5 0.0 2.1e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAX17981.1 - 2.6e-10 40.8 0.0 1e-06 29.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX17981.1 - 3.5e-10 40.3 0.3 0.00015 22.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAX17981.1 - 9.2e-08 32.7 1.3 8.6e-07 29.5 1.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAX17981.1 - 2.6e-07 30.7 0.4 0.003 17.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX17981.1 - 1.3e-06 28.3 0.1 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GAX17981.1 - 4e-06 26.3 0.5 0.00049 19.5 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX17981.1 - 0.00019 21.6 0.1 0.001 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX17981.1 - 0.00053 19.6 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAX17981.1 - 0.0028 17.4 0.0 0.0082 15.9 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAX17981.1 - 0.0062 17.1 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAX17981.1 - 0.0072 16.6 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAX17981.1 - 0.009 15.7 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain CPT PF07931.12 GAX17981.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 GAX17981.1 - 0.015 15.4 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAX17981.1 - 0.019 15.4 0.0 0.096 13.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 GAX17981.1 - 0.021 13.8 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain ResIII PF04851.15 GAX17981.1 - 0.023 14.7 0.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 GAX17981.1 - 0.023 15.2 0.0 0.069 13.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 GAX17981.1 - 0.024 14.6 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DNA_pol3_delta PF06144.13 GAX17981.1 - 0.039 13.7 0.2 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 GAX17981.1 - 0.039 14.3 2.3 1.1 9.6 2.3 2.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAX17981.1 - 0.046 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain PhoH PF02562.16 GAX17981.1 - 0.046 13.2 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DnaB_C PF03796.15 GAX17981.1 - 0.049 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 GAX17981.1 - 0.058 13.8 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 1 0 RNA helicase TsaE PF02367.17 GAX17981.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAX17981.1 - 0.066 12.7 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAX17981.1 - 0.076 12.3 0.8 0.25 10.6 0.2 2.1 2 1 0 2 2 1 0 Zeta toxin TniB PF05621.11 GAX17981.1 - 0.09 12.2 0.0 1.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein Ank_5 PF13857.6 GAX17982.1 - 1.8e-08 34.4 0.0 9.4e-05 22.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX17982.1 - 1.1e-07 32.3 0.0 3.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX17982.1 - 9.1e-06 26.1 0.1 0.14 12.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX17982.1 - 0.014 15.9 0.0 2.2 9.1 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 GAX17982.1 - 0.098 13.1 0.0 0.69 10.5 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeat Glyco_transf_28 PF03033.20 GAX17983.1 - 7.4e-11 42.2 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAX17983.1 - 4.8e-08 32.3 0.0 1.1e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAX17983.1 - 4.8e-06 26.6 0.0 9.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF3592 PF12158.8 GAX17985.1 - 0.0066 16.5 0.1 0.016 15.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3592) Band_7 PF01145.25 GAX17986.1 - 1e-25 90.8 2.2 1.9e-25 89.9 2.2 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_S3Ae PF01015.18 GAX17986.1 - 0.05 13.2 0.2 0.083 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribosomal S3Ae family MORN PF02493.20 GAX17987.1 - 0.0068 16.2 9.3 0.085 12.8 0.6 4.0 3 0 0 3 3 3 2 MORN repeat DUF5098 PF17023.5 GAX17989.1 - 0.013 14.4 2.5 2.3 7.1 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5098) TPR_2 PF07719.17 GAX17989.1 - 0.17 12.1 0.0 4.6 7.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 GAX17990.1 - 0.69 10.7 4.5 0.61 10.8 1.2 2.5 3 0 0 3 3 3 0 U3 snoRNA associated SPRY PF00622.28 GAX17991.1 - 4.8e-20 71.9 0.2 1.2e-19 70.6 0.2 1.7 1 1 0 1 1 1 1 SPRY domain SPRY PF00622.28 GAX17992.1 - 2.1e-19 69.8 0.3 4.1e-19 68.9 0.3 1.5 1 1 0 1 1 1 1 SPRY domain TPR_12 PF13424.6 GAX17994.1 - 1.2e-09 38.3 2.7 0.00026 21.2 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX17994.1 - 1.2e-05 25.0 1.7 0.76 9.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX17994.1 - 6e-05 22.9 0.2 0.17 12.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX17994.1 - 0.0039 17.7 0.3 0.013 16.0 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX17994.1 - 0.0041 16.9 0.3 0.031 14.1 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SPT6_acidic PF14632.6 GAX17995.1 - 0.98 10.1 13.1 0.84 10.3 1.4 3.4 3 0 0 3 3 3 0 Acidic N-terminal SPT6 Med13_C PF06333.12 GAX17995.1 - 1.2 8.3 6.4 0.51 9.6 0.2 2.5 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Catalase PF00199.19 GAX17996.1 - 3e-190 632.3 0.0 3.7e-190 632.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAX17996.1 - 4.7e-21 74.8 0.2 2.4e-20 72.5 0.1 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive WGG PF10273.9 GAX17997.1 - 4.1e-19 69.0 0.3 7e-19 68.3 0.3 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 GDI PF00996.18 GAX17998.1 - 4e-44 150.9 0.0 2.9e-21 75.5 0.0 3.1 3 0 0 3 3 3 3 GDP dissociation inhibitor IL12p40_C PF10420.9 GAX17998.1 - 0.011 16.2 0.8 0.57 10.7 0.0 2.6 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus DUF4618 PF15397.6 GAX17999.1 - 0.002 17.6 0.1 0.0032 16.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) zf-U1 PF06220.12 GAX18000.1 - 1.8e-06 27.6 0.2 2.9e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 GAX18000.1 - 0.0091 16.3 2.0 0.032 14.5 2.0 1.9 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding MetallophosC PF16370.5 GAX18000.1 - 0.036 14.3 0.4 0.11 12.8 0.4 1.8 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Semialdhyde_dh PF01118.24 GAX18000.1 - 0.095 13.1 0.9 0.67 10.4 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain TLD PF07534.16 GAX18001.1 - 2.7e-20 73.0 0.0 3.5e-19 69.4 0.0 2.3 2 1 0 2 2 2 1 TLD CENP-T_N PF16171.5 GAX18001.1 - 0.033 13.1 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus IBV_3C PF03620.13 GAX18001.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 IBV 3C protein Cob_adeno_trans PF01923.18 GAX18002.1 - 3.6e-54 183.3 0.0 5.8e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF5522 PF17653.1 GAX18002.1 - 1.6e-23 82.4 2.8 3.7e-23 81.2 2.8 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Mito_carr PF00153.27 GAX18003.1 - 8.3e-49 163.5 0.5 4.7e-21 74.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane PF01061.24 GAX18004.1 - 2e-33 115.6 14.9 2.9e-33 115.1 14.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX18004.1 - 2.8e-25 89.4 0.0 4.2e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAX18004.1 - 1.2e-05 25.3 0.0 0.076 12.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX18004.1 - 7.9e-05 23.1 0.0 0.00013 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAX18004.1 - 0.00016 21.6 0.2 0.00029 20.8 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 GAX18004.1 - 0.00025 20.6 0.0 0.00076 19.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX18004.1 - 0.001 19.4 0.0 0.0024 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX18004.1 - 0.006 15.7 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 GAX18004.1 - 0.011 15.4 0.1 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX18004.1 - 0.011 15.5 0.4 0.028 14.2 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 GAX18004.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAX18004.1 - 0.017 15.5 0.0 0.049 14.0 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAX18004.1 - 0.02 14.8 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 GAX18004.1 - 0.031 14.8 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAX18004.1 - 0.044 13.9 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX18004.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX18004.1 - 0.06 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 GAX18004.1 - 0.06 13.1 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 1 0 Cytidylate kinase AAA_5 PF07728.14 GAX18004.1 - 0.061 13.3 0.0 0.16 12.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 GAX18004.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 GAX18004.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 GAX18004.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 2 0 0 2 2 1 0 NTPase AAA_13 PF13166.6 GAX18004.1 - 0.11 11.1 0.0 0.65 8.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAX18004.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 GAX18004.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAX18004.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FumaraseC_C PF10415.9 GAX18006.1 - 0.044 14.2 0.0 3.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Fumarase C C-terminus zf-H3C2 PF16721.5 GAX18007.1 - 0.13 12.6 0.1 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding Abhydrolase_1 PF00561.20 GAX18008.1 - 2.3e-12 47.1 0.1 3.2e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX18008.1 - 5e-06 27.3 11.1 6.5e-06 26.9 11.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX18008.1 - 0.031 13.5 0.1 0.058 12.7 0.1 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 FtsL PF04999.13 GAX18008.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Cell division protein FtsL CBS PF00571.28 GAX18010.1 - 3.4e-19 69.1 0.1 3.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 CBS domain Robl_LC7 PF03259.17 GAX18010.1 - 0.14 11.9 0.1 0.37 10.6 0.0 1.8 1 1 0 1 1 1 0 Roadblock/LC7 domain Ras PF00071.22 GAX18011.1 - 3.4e-58 195.8 0.0 3.9e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX18011.1 - 2.8e-34 117.9 0.1 3.7e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX18011.1 - 5.9e-16 58.4 0.0 7.5e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX18011.1 - 3.6e-06 27.1 0.0 5.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX18011.1 - 4.3e-05 23.0 0.0 5.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAX18011.1 - 0.00039 19.9 0.0 0.00056 19.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAX18011.1 - 0.0005 19.7 0.1 0.0022 17.6 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain COXG PF06240.13 GAX18011.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) ETS_PEA3_N PF04621.13 GAX18012.1 - 0.87 9.4 6.5 1.1 9.0 6.5 1.0 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Porphobil_deam PF01379.20 GAX18013.1 - 2.4e-74 249.3 0.0 3e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 GAX18013.1 - 3.7e-17 62.5 0.3 6.8e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Metal_resist PF13801.6 GAX18013.1 - 0.06 13.5 1.1 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance RWD PF05773.22 GAX18014.1 - 4.8e-16 59.1 0.1 1.1e-15 57.9 0.1 1.7 1 0 0 1 1 1 1 RWD domain Cu-oxidase PF00394.22 GAX18014.1 - 1.1e-15 58.2 0.0 4.7e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAX18014.1 - 3.3e-14 52.8 1.4 3.3e-14 52.8 1.4 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAX18014.1 - 2.4e-10 40.5 0.1 5.3e-05 23.2 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cornifin PF02389.15 GAX18014.1 - 0.014 15.5 12.8 0.014 15.5 12.8 2.1 2 0 0 2 2 2 0 Cornifin (SPRR) family DFRP_C PF16543.5 GAX18014.1 - 0.016 15.7 13.7 0.016 15.7 13.7 2.1 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 TFIIA PF03153.13 GAX18014.1 - 0.2 11.6 21.7 0.4 10.6 21.7 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAP PF07174.11 GAX18014.1 - 2.3 7.6 15.8 3.9 6.9 15.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PQQ_3 PF13570.6 GAX18015.1 - 9.3e-06 26.0 2.0 0.099 13.2 0.0 3.8 4 0 0 4 4 4 2 PQQ-like domain WD40_like PF17005.5 GAX18015.1 - 0.00076 18.9 0.0 1.3 8.3 0.0 3.0 2 2 1 3 3 3 2 WD40-like domain CPSF_A PF03178.15 GAX18015.1 - 0.0035 16.7 0.1 0.77 9.0 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region DNA_pol_B PF00136.21 GAX18016.1 - 1.3e-116 390.0 0.0 2.5e-116 389.1 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 GAX18016.1 - 6.5e-38 130.3 0.0 1.6e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 GAX18016.1 - 4.2e-30 105.1 0.0 8.5e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 GAX18016.1 - 7.6e-20 70.8 8.4 7.6e-20 70.8 8.4 2.1 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 GAX18016.1 - 0.004 16.1 0.0 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 GAX18016.1 - 0.068 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB CNOT1_HEAT_N PF16419.5 GAX18016.1 - 0.082 12.6 1.1 0.15 11.7 1.1 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Tab2_like PF06485.11 GAX18017.1 - 2.6e-81 273.1 0.1 4.9e-81 272.2 0.0 1.4 2 0 0 2 2 2 1 RNA-binding protein Tab2/Atab2 Cyclin_N PF00134.23 GAX18019.1 - 5.8e-20 71.3 0.3 8.2e-15 54.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX18019.1 - 0.00026 21.1 0.5 0.0027 17.8 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 GAX18019.1 - 0.0086 16.4 0.1 0.1 13.0 0.0 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain Aa_trans PF01490.18 GAX18020.1 - 3.7e-39 134.6 22.6 6.5e-39 133.8 22.6 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.27 GAX18021.1 - 1.9e-30 106.2 0.0 4.4e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX18021.1 - 2.6e-19 70.0 13.1 2.6e-19 70.0 13.1 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 GAX18021.1 - 5.4e-08 32.5 0.2 1.1e-05 25.0 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX18021.1 - 0.0006 20.1 0.1 0.0023 18.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX18021.1 - 0.007 16.1 0.2 0.015 15.0 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAX18021.1 - 0.0081 16.7 0.4 0.018 15.6 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX18021.1 - 0.021 15.2 0.7 0.061 13.7 0.7 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GAX18021.1 - 0.058 13.1 0.9 0.14 11.9 0.9 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX18021.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 GAX18021.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 GAX18021.1 - 0.085 12.3 0.5 9.3 5.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_membrane_3 PF13748.6 GAX18021.1 - 0.094 11.9 0.1 0.094 11.9 0.1 2.5 3 0 0 3 3 3 0 ABC transporter transmembrane region AAA_21 PF13304.6 GAX18021.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GAX18021.1 - 0.19 12.2 0.0 0.81 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain PDZ PF00595.24 GAX18022.1 - 1.2e-08 35.1 0.0 0.00024 21.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 GAX18022.1 - 0.0011 18.8 0.0 0.044 13.6 0.0 2.7 2 0 0 2 2 2 1 PDZ domain BTB_2 PF02214.22 GAX18022.1 - 0.007 16.7 0.0 0.029 14.7 0.0 2.1 1 0 0 1 1 1 1 BTB/POZ domain PTRF_SDPR PF15237.6 GAX18022.1 - 0.035 13.7 2.7 0.14 11.8 0.4 2.1 2 0 0 2 2 2 0 PTRF/SDPR family PDZ_2 PF13180.6 GAX18022.1 - 0.059 13.7 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Pyrophosphatase PF00719.19 GAX18022.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Inorganic pyrophosphatase BRE1 PF08647.11 GAX18022.1 - 0.14 12.2 6.2 0.2 11.7 1.5 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Peptidase_C2 PF00648.21 GAX18023.1 - 1.5e-43 149.0 0.0 3.3e-43 147.8 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease NAM-associated PF14303.6 GAX18023.1 - 0.18 12.5 7.3 0.33 11.7 7.3 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 GAX18023.1 - 4 7.0 16.7 6.3 6.3 16.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 GAX18023.1 - 4 6.2 7.3 5.6 5.7 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 GAX18023.1 - 8.5 4.6 7.5 12 4.1 7.5 1.1 1 0 0 1 1 1 0 Menin TRAM_LAG1_CLN8 PF03798.16 GAX18024.1 - 1.8e-13 50.7 18.8 2.4e-13 50.3 18.8 1.1 1 0 0 1 1 1 1 TLC domain DUF4234 PF14018.6 GAX18024.1 - 2.9 8.1 9.5 2 8.6 2.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) UPF0029 PF01205.19 GAX18025.1 - 2.8e-31 108.0 0.6 4.9e-31 107.2 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 MMS1_N PF10433.9 GAX18025.1 - 0.0084 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term HSF_DNA-bind PF00447.17 GAX18026.1 - 3.4e-15 56.4 0.0 5.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding SHMT PF00464.19 GAX18028.1 - 1.3e-174 580.5 0.0 1.5e-174 580.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 GAX18028.1 - 3.6e-05 23.2 0.0 8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Mlh1_C PF16413.5 GAX18029.1 - 2.9e-51 174.4 0.0 2e-49 168.4 0.0 2.7 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 GAX18029.1 - 5.4e-18 64.8 0.1 1e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAX18029.1 - 3.2e-07 30.3 0.0 6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAX18029.1 - 0.00016 22.1 0.0 0.0004 20.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dynactin_p22 PF07426.11 GAX18029.1 - 0.56 10.0 4.2 0.71 9.7 0.2 3.0 2 1 1 3 3 3 0 Dynactin subunit p22 AAA_23 PF13476.6 GAX18031.1 - 1.7e-19 71.1 3.0 1.7e-19 71.1 3.0 5.0 2 2 1 3 3 1 1 AAA domain SMC_N PF02463.19 GAX18031.1 - 7.6e-18 64.8 10.0 1.7e-17 63.6 10.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX18031.1 - 0.00015 21.7 1.2 0.0034 17.2 0.2 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX18031.1 - 0.0024 17.6 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 GAX18031.1 - 0.016 14.8 0.0 0.016 14.8 0.0 4.7 5 1 0 6 6 6 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX18031.1 - 0.064 12.6 0.0 0.064 12.6 0.0 3.7 4 1 0 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GAX18031.1 - 0.088 13.3 0.1 0.088 13.3 0.1 5.2 4 2 0 4 4 3 0 ABC transporter AAA_16 PF13191.6 GAX18031.1 - 0.26 11.6 0.0 0.26 11.6 0.0 4.2 3 1 0 3 3 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAX18031.1 - 0.73 9.7 0.0 0.73 9.7 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase MMR_HSR1 PF01926.23 GAX18031.1 - 0.78 9.8 2.4 8.2 6.5 2.4 2.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase MSA-2c PF12238.8 GAX18031.1 - 3.4 7.6 6.5 13 5.7 1.6 2.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c Nup35_RRM_2 PF14605.6 GAX18032.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MoaE PF02391.17 GAX18032.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 MoaE protein YCII PF03795.14 GAX18033.1 - 0.0075 16.7 0.0 0.028 14.8 0.0 2.0 2 0 0 2 2 2 1 YCII-related domain Annexin PF00191.20 GAX18035.1 - 7.3e-43 144.5 0.1 3.2e-10 39.9 0.2 4.1 4 0 0 4 4 4 4 Annexin Silic_transp PF03842.13 GAX18036.1 - 6.9e-225 747.2 6.7 8.2e-225 746.9 6.7 1.0 1 0 0 1 1 1 1 Silicon transporter Prefoldin_2 PF01920.20 GAX18036.1 - 0.027 14.4 0.8 0.046 13.7 0.8 1.3 1 0 0 1 1 1 0 Prefoldin subunit MatE PF01554.18 GAX18037.1 - 7.6e-11 41.9 27.2 1.9e-10 40.6 8.2 3.5 2 2 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAX18037.1 - 2.3e-05 24.5 3.3 2.3e-05 24.5 3.3 3.5 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain eRF1_3 PF03465.15 GAX18037.1 - 0.065 13.7 0.4 0.17 12.4 0.4 1.7 1 0 0 1 1 1 0 eRF1 domain 3 Plant_tran PF04827.14 GAX18038.1 - 2.2e-21 76.4 0.0 3.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 GAX18038.1 - 3.7e-18 65.7 0.0 7.2e-18 64.7 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Myc_N PF01056.18 GAX18038.1 - 0.038 13.9 0.5 0.08 12.8 0.5 1.5 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.11 GAX18038.1 - 0.081 13.0 4.6 0.17 11.9 4.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 GAX18038.1 - 0.12 10.5 11.1 0.19 9.8 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GAX18038.1 - 0.16 10.1 6.3 0.23 9.6 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 GAX18038.1 - 0.34 10.8 3.6 0.67 9.8 3.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.6 GAX18038.1 - 0.42 11.0 17.4 0.44 11.0 10.6 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 GAX18038.1 - 0.47 10.1 4.4 0.9 9.2 4.4 1.4 1 0 0 1 1 1 0 FAM176 family AIM3 PF17096.5 GAX18038.1 - 0.63 11.0 5.5 0.21 12.6 1.9 2.1 2 0 0 2 2 1 0 Altered inheritance of mitochondria protein 3 NOA36 PF06524.12 GAX18038.1 - 0.67 9.2 14.6 1.6 8.0 14.6 1.5 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GAX18038.1 - 0.88 7.8 4.4 1.4 7.2 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 GAX18038.1 - 5.9 5.9 20.3 11 5.0 20.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 GAX18039.1 - 0.041 13.2 39.3 0.061 12.7 39.3 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 GAX18039.1 - 1.7 8.6 34.0 3.3 7.6 34.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RsbRD_N PF14361.6 GAX18039.1 - 5.1 7.8 6.4 0.69 10.6 1.5 2.1 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain PFK PF00365.20 GAX18040.1 - 2.3e-57 194.5 0.0 2.9e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 GAX18040.1 - 0.052 13.2 0.1 0.33 10.6 0.0 2.3 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 GAX18040.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase PNTB PF02233.16 GAX18041.1 - 2e-165 551.2 31.6 3.3e-165 550.5 22.2 2.3 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAX18041.1 - 1.2e-70 237.1 4.9 1.2e-70 237.1 4.9 3.0 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAX18041.1 - 2.9e-36 124.8 0.2 7.9e-36 123.4 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAX18041.1 - 1.7e-27 95.7 1.3 1.7e-27 95.7 1.3 4.4 4 1 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 GAX18041.1 - 0.00074 18.9 0.2 0.046 13.1 0.1 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAX18041.1 - 0.0048 16.9 3.9 0.0052 16.8 0.3 2.7 2 1 0 3 3 3 1 Zinc-binding dehydrogenase Silic_transp PF03842.13 GAX18042.1 - 3.6e-223 741.5 5.5 4.2e-223 741.3 5.5 1.0 1 0 0 1 1 1 1 Silicon transporter Prefoldin_2 PF01920.20 GAX18042.1 - 0.036 14.0 1.2 0.064 13.2 1.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit Sterol_MT_C PF08498.10 GAX18045.1 - 6e-26 90.6 0.1 1.6e-25 89.2 0.1 1.7 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAX18045.1 - 6.6e-16 58.7 0.0 1.5e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX18045.1 - 1.8e-14 53.8 0.0 2.9e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX18045.1 - 8.6e-14 52.0 0.0 2.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX18045.1 - 3.4e-12 46.2 0.0 5.1e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAX18045.1 - 2.8e-09 37.0 0.0 7.9e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX18045.1 - 8.3e-09 36.1 0.0 2.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 GAX18045.1 - 0.0028 17.2 0.1 0.0053 16.3 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 GAX18045.1 - 0.0044 16.2 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAX18045.1 - 0.079 14.0 0.0 0.27 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Tic22 PF04278.12 GAX18046.1 - 1.5e-11 44.2 0.4 4.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Tic22-like family DUF1336 PF07059.12 GAX18047.1 - 2.1e-53 181.7 0.0 2.5e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Tfb4 PF03850.14 GAX18048.1 - 2.4e-49 168.3 1.1 3.4e-49 167.8 1.1 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C3HC4_3 PF13920.6 GAX18048.1 - 0.13 12.2 0.9 0.34 10.8 0.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PseudoU_synth_2 PF00849.22 GAX18049.1 - 1.4e-24 87.0 0.0 3.2e-24 85.8 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF438 PF04282.13 GAX18050.1 - 0.043 13.8 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF438) DUF2802 PF10975.8 GAX18050.1 - 0.18 11.9 1.3 3.8 7.7 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) PseudoU_synth_2 PF00849.22 GAX18051.1 - 8.1e-24 84.5 0.0 1.5e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase NTP_transf_3 PF12804.7 GAX18051.1 - 0.072 13.4 0.2 16 5.8 0.0 2.5 2 1 0 2 2 2 0 MobA-like NTP transferase domain cobW PF02492.19 GAX18052.1 - 2.9e-44 150.8 0.3 8.1e-44 149.3 0.3 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX18052.1 - 1.5e-13 50.5 0.0 5e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 GAX18052.1 - 0.0034 17.4 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CHASE5 PF17149.4 GAX18052.1 - 0.0081 16.1 0.1 0.2 11.6 0.0 2.7 2 1 1 3 3 3 1 Periplasmic sensor domain found in signal transduction proteins RsgA_GTPase PF03193.16 GAX18052.1 - 0.041 13.8 0.1 5.1 7.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAX18052.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 GAX18052.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 GAX18052.1 - 0.11 11.5 0.1 0.71 8.9 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.6 GAX18052.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX18052.1 - 0.17 12.0 0.1 1.2 9.2 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase dCMP_cyt_deam_1 PF00383.23 GAX18054.1 - 1.1e-14 54.2 0.0 5e-14 52.0 0.0 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX18054.1 - 0.00043 20.1 0.1 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase CRS1_YhbY PF01985.21 GAX18054.1 - 0.0012 18.9 0.2 0.0025 18.0 0.2 1.5 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Inv-AAD PF18785.1 GAX18054.1 - 0.0022 17.9 0.0 0.036 13.9 0.0 2.4 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 GAX18054.1 - 0.052 13.4 0.6 0.91 9.4 0.6 2.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain RAI1 PF08652.11 GAX18054.1 - 0.073 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease MORN PF02493.20 GAX18055.1 - 1.4e-28 97.1 40.6 4.3e-07 29.4 0.4 7.4 7 0 0 7 7 7 7 MORN repeat MORN PF02493.20 GAX18056.1 - 3.5e-35 117.8 38.4 1.6e-08 34.0 1.1 7.3 7 0 0 7 7 7 6 MORN repeat DUF3048_C PF17479.2 GAX18056.1 - 0.032 14.6 1.0 0.12 12.8 0.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain CPSase_L_D2 PF02786.17 GAX18057.1 - 5.1e-73 245.0 0.0 8.6e-73 244.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAX18057.1 - 2.4e-28 98.9 0.0 9.2e-28 97.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAX18057.1 - 6.9e-28 96.9 0.0 1.6e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAX18057.1 - 2.4e-14 52.9 0.3 5e-14 51.9 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAX18057.1 - 2.9e-07 30.2 0.0 5.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAX18057.1 - 9.2e-07 28.6 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAX18057.1 - 1.1e-05 25.2 0.0 0.00039 20.2 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.11 GAX18057.1 - 2.4e-05 24.0 0.0 7.3e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 GAX18057.1 - 8.3e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 GAX18057.1 - 0.0032 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 GAX18057.1 - 0.0053 17.4 0.2 4.3 8.1 0.1 2.9 2 0 0 2 2 2 1 HlyD family secretion protein ATP-grasp_3 PF02655.14 GAX18057.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain GCV_H PF01597.19 GAX18057.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 GAX18057.1 - 0.058 13.2 0.0 1.2 8.9 0.0 2.5 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 GAX18057.1 - 0.16 11.9 0.2 1.5 8.8 0.1 2.6 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain Aminotran_1_2 PF00155.21 GAX18061.1 - 1.2e-56 192.5 0.0 1.3e-56 192.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAX18061.1 - 0.018 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAX18061.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase ParA PF10609.9 GAX18062.1 - 3.6e-74 249.3 0.5 2.9e-67 226.7 0.9 2.2 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 GAX18062.1 - 5.3e-14 52.6 0.0 1.3e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) FeS_assembly_P PF01883.19 GAX18062.1 - 2.5e-12 46.8 0.0 1.3e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 GAX18062.1 - 6.6e-10 39.1 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX18062.1 - 7.9e-10 38.9 0.9 2.5e-07 30.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 GAX18062.1 - 4.3e-08 32.8 0.0 7.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 GAX18062.1 - 6.2e-05 22.6 0.8 0.0016 18.0 0.8 2.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 GAX18062.1 - 0.0014 17.9 5.0 0.051 12.8 0.5 2.9 2 1 1 3 3 3 2 Anion-transporting ATPase Fer4_NifH PF00142.18 GAX18062.1 - 0.018 14.5 0.1 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF3945 PF13101.6 GAX18062.1 - 0.057 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Calc_CGRP_IAPP PF00214.19 GAX18062.1 - 0.075 13.4 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family VirC1 PF07015.11 GAX18062.1 - 0.13 11.5 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 VirC1 protein Fic PF02661.18 GAX18066.1 - 1e-16 61.6 0.1 1e-16 61.6 0.1 2.7 3 0 0 3 3 3 1 Fic/DOC family zf-RING_2 PF13639.6 GAX18066.1 - 5.4e-07 29.8 7.7 5.4e-07 29.8 7.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 GAX18066.1 - 0.00014 22.1 5.0 0.00014 22.1 5.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAX18066.1 - 0.00017 21.4 5.2 0.00017 21.4 5.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX18066.1 - 0.0018 18.3 1.4 0.0018 18.3 1.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAX18066.1 - 0.011 15.6 9.4 0.011 15.6 9.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2717 PF10911.8 GAX18066.1 - 0.22 11.3 0.5 22 4.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2717) RINGv PF12906.7 GAX18066.1 - 0.43 10.7 8.7 1.3 9.2 8.7 1.9 1 0 0 1 1 1 0 RING-variant domain ADH_zinc_N PF00107.26 GAX18067.1 - 1.9e-07 31.1 0.0 4.3e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX18067.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain S1 PF00575.23 GAX18067.1 - 0.019 15.3 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 S1 RNA binding domain PRK PF00485.18 GAX18068.1 - 2.3e-71 239.6 0.0 3.5e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 GAX18068.1 - 0.14 12.6 0.0 0.67 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain UBX PF00789.20 GAX18069.1 - 9.8e-08 32.1 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain Atg14 PF10186.9 GAX18069.1 - 0.00071 18.8 3.2 0.0012 18.0 3.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ISG65-75 PF11727.8 GAX18069.1 - 0.0088 15.3 3.7 0.0088 15.3 3.7 2.0 2 0 0 2 2 2 1 Invariant surface glycoprotein DNA_pol_phi PF04931.13 GAX18069.1 - 0.056 11.5 14.5 0.015 13.4 9.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi BSP_II PF05432.11 GAX18069.1 - 0.087 12.5 13.4 0.084 12.6 6.8 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.16 GAX18069.1 - 0.098 11.8 4.9 0.056 12.6 0.5 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.10 GAX18069.1 - 0.65 10.3 8.5 4.9 7.4 1.0 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.19 GAX18069.1 - 0.77 7.6 8.0 3.8 5.3 3.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family VanY PF02557.17 GAX18069.1 - 0.92 9.3 6.1 2.3 8.0 6.1 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase CSRNP_N PF16019.5 GAX18069.1 - 6.6 6.6 13.0 1 9.2 1.2 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Asp_Arg_Hydrox PF05118.15 GAX18071.1 - 3e-36 124.6 0.1 5e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Raptor_N PF14538.6 GAX18071.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain GST_N_3 PF13417.6 GAX18073.1 - 3.2e-12 46.7 0.0 7.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX18073.1 - 2.9e-10 40.3 0.0 7.2e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX18073.1 - 3.3e-08 33.7 0.0 6.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MoaC PF01967.21 GAX18074.1 - 6.8e-45 152.5 5.2 1.2e-44 151.7 5.2 1.4 1 0 0 1 1 1 1 MoaC family MazG-like PF12643.7 GAX18074.1 - 1.8e-05 24.9 1.0 0.0067 16.7 0.0 2.6 2 0 0 2 2 2 2 MazG-like family MazG PF03819.17 GAX18074.1 - 0.077 13.2 0.3 0.18 12.0 0.3 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Zip PF02535.22 GAX18074.1 - 2.2 7.4 11.6 1.4 8.1 6.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter TPR_12 PF13424.6 GAX18075.1 - 1e-32 112.2 24.9 9.5e-11 41.8 0.0 7.6 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18075.1 - 7.6e-14 51.1 16.5 0.03 14.2 0.1 8.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18075.1 - 5.7e-13 47.9 18.8 0.0056 16.7 0.1 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18075.1 - 3.8e-12 45.5 11.7 0.00039 20.1 0.2 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX18075.1 - 5.9e-07 29.1 13.5 0.49 10.6 0.5 6.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18075.1 - 7.1e-07 29.0 4.5 0.015 15.4 0.1 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX18075.1 - 6.8e-06 25.7 1.4 6.8e-06 25.7 1.4 3.2 2 2 2 4 4 4 3 MalT-like TPR region MIT PF04212.18 GAX18075.1 - 0.0084 16.1 12.4 3 8.0 0.1 6.3 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 GAX18075.1 - 0.023 15.2 10.1 0.1 13.1 0.4 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX18075.1 - 0.049 14.3 19.8 5.8 7.8 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18075.1 - 0.081 13.8 14.6 4.1 8.5 0.4 6.1 5 2 2 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18075.1 - 0.11 12.2 6.5 2.7 7.8 0.2 4.7 5 0 0 5 5 5 0 TPR repeat DUF1824 PF08854.10 GAX18075.1 - 0.11 12.4 0.1 0.43 10.5 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) Hum_adeno_E3A PF05393.11 GAX18075.1 - 0.12 12.4 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein TPR_3 PF07720.12 GAX18075.1 - 0.36 10.9 2.0 3.7 7.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18075.1 - 1.2 9.8 12.5 38 5.0 0.1 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat PrmA PF06325.13 GAX18076.1 - 1.6e-34 119.7 0.0 2.1e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAX18076.1 - 4.3e-10 39.6 0.0 4.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX18076.1 - 3.9e-08 33.9 0.0 6.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX18076.1 - 3.5e-07 29.9 0.0 4.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAX18076.1 - 6.8e-05 22.8 0.0 0.0012 18.7 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX18076.1 - 0.00022 21.2 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX18076.1 - 0.00025 20.9 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 GAX18076.1 - 0.00029 21.4 0.0 0.00043 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX18076.1 - 0.0005 19.8 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltrans_SAM PF10672.9 GAX18076.1 - 0.00072 18.8 0.0 0.00093 18.4 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Met_10 PF02475.16 GAX18076.1 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 GAX18076.1 - 0.0035 18.1 0.0 0.0048 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX18076.1 - 0.0057 16.0 0.0 0.009 15.3 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.18 GAX18076.1 - 0.017 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Methyltransf_32 PF13679.6 GAX18076.1 - 0.045 13.8 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 GAX18076.1 - 0.067 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_9 PF08003.11 GAX18076.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 GAX18076.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TPR_12 PF13424.6 GAX18078.1 - 3.9e-10 39.9 0.1 5e-06 26.7 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX18078.1 - 0.034 14.2 0.8 3.4 7.9 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 GAX18079.1 - 4e-57 193.3 3.4 5.2e-49 166.8 0.4 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Post_transc_reg PF13797.6 GAX18079.1 - 0.085 12.7 0.3 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Post-transcriptional regulator Sacchrp_dh_NADP PF03435.18 GAX18080.1 - 3.7e-11 43.4 0.0 5.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAX18080.1 - 0.06 13.4 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 GAX18080.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 KR domain Response_reg PF00072.24 GAX18081.1 - 1e-19 70.8 0.0 1.1e-18 67.4 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAX18081.1 - 4.1e-05 23.5 1.6 0.00019 21.4 1.6 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 GAX18081.1 - 0.0025 18.4 0.0 0.0054 17.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain RuvA_C PF07499.13 GAX18081.1 - 0.0052 17.2 0.2 0.21 12.1 0.1 2.5 2 0 0 2 2 2 1 RuvA, C-terminal domain MORN PF02493.20 GAX18084.1 - 4.5e-32 108.0 32.0 2.9e-06 26.8 0.4 7.3 7 0 0 7 7 7 7 MORN repeat Pkinase PF00069.25 GAX18085.1 - 3.1e-63 213.6 0.0 6.1e-63 212.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18085.1 - 1.3e-30 106.6 0.0 2.1e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX18085.1 - 6.9e-06 25.6 0.0 5.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAX18085.1 - 0.00025 19.9 0.4 0.00025 19.9 0.4 2.5 2 2 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAX18085.1 - 0.00077 19.5 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX18085.1 - 0.002 17.5 0.0 0.0051 16.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAX18085.1 - 0.055 13.1 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 GAX18085.1 - 0.13 13.0 0.2 0.13 13.0 0.2 4.0 4 0 0 4 4 4 0 Protein kinase C terminal domain DRMBL PF07522.14 GAX18086.1 - 6.4e-23 81.0 0.0 1.5e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GAX18086.1 - 2.4e-06 27.2 0.2 5e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX18086.1 - 0.0011 19.1 0.2 0.002 18.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lsr2 PF11774.8 GAX18086.1 - 0.14 12.3 0.7 0.36 11.0 0.7 1.7 1 0 0 1 1 1 0 Lsr2 NCD3G PF07562.14 GAX18086.1 - 4.1 7.5 7.7 2.2 8.3 0.8 2.8 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR YL1 PF05764.13 GAX18086.1 - 7.2 6.7 12.3 2.3 8.3 8.1 2.2 2 1 0 2 2 2 0 YL1 nuclear protein Peptidase_U4 PF03419.13 GAX18089.1 - 0.099 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA UPF0542 PF15086.6 GAX18089.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 MerT PF02411.15 GAX18089.1 - 0.19 11.8 2.0 0.17 11.9 0.4 1.8 1 1 0 2 2 2 0 MerT mercuric transport protein Rft-1 PF04506.13 GAX18091.1 - 1.1e-88 298.3 12.2 1.5e-88 297.8 12.2 1.1 1 0 0 1 1 1 1 Rft protein Palm_thioest PF02089.15 GAX18091.1 - 0.19 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Glyco_transf_92 PF01697.27 GAX18092.1 - 1.1e-17 64.6 0.1 1.8e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GAX18092.1 - 4.3e-09 36.8 0.0 1.2e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 DNA_pol_phi PF04931.13 GAX18093.1 - 0.0079 14.4 7.0 0.012 13.7 7.0 1.2 1 0 0 1 1 1 1 DNA polymerase phi NOA36 PF06524.12 GAX18093.1 - 2 7.7 5.8 3.4 6.9 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein ThrE PF06738.12 GAX18094.1 - 0.0058 16.0 0.0 0.0063 15.9 0.0 1.0 1 0 0 1 1 1 1 Putative threonine/serine exporter DUF948 PF06103.11 GAX18094.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CAF1 PF04857.20 GAX18095.1 - 1.9e-18 66.8 1.9 7.8e-10 38.4 0.0 2.7 1 1 1 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 GAX18095.1 - 0.12 12.0 0.0 15 5.3 0.0 2.4 2 1 0 2 2 2 0 3'-5' exonuclease WD40 PF00400.32 GAX18096.1 - 0.14 13.1 0.8 12 6.9 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat ERGIC_N PF13850.6 GAX18097.1 - 2.7e-22 78.9 1.0 8.1e-22 77.4 0.2 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 GAX18097.1 - 3.8e-20 71.8 0.1 1.8e-17 63.2 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin COPIIcoated_ERV PF07970.12 GAX18097.1 - 7.1e-05 22.7 0.5 0.00024 21.0 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter Thioredoxin_2 PF13098.6 GAX18097.1 - 0.00069 20.0 0.1 0.0018 18.7 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX18097.1 - 0.0033 17.6 0.1 0.0086 16.2 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX18097.1 - 0.0065 16.8 0.2 0.033 14.5 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX18097.1 - 0.09 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin HemeBinding_Shp PF11545.8 GAX18097.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp NOG1 PF06858.14 GAX18098.1 - 2.1e-17 62.6 0.0 5e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GAX18098.1 - 2.2e-15 56.7 0.0 7.7e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1_N PF17835.1 GAX18098.1 - 9.2e-11 42.0 0.5 1.8e-10 41.0 0.5 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain FeoB_N PF02421.18 GAX18098.1 - 1.2e-05 24.9 0.1 3.1e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF4733 PF15878.5 GAX18098.1 - 0.00049 20.5 0.7 0.32 11.5 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4733) AAA_16 PF13191.6 GAX18098.1 - 0.00072 20.0 0.0 0.014 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 GAX18098.1 - 0.016 15.0 0.4 0.13 11.9 0.0 2.3 2 1 1 3 3 3 0 AAA ATPase domain AAA_5 PF07728.14 GAX18098.1 - 0.024 14.6 0.2 0.48 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAX18098.1 - 0.05 14.2 0.0 0.83 10.2 0.0 2.6 1 1 0 2 2 2 0 AAA domain Quaking_NLS PF16551.5 GAX18098.1 - 0.091 12.4 1.4 8.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Putative nuclear localisation signal of quaking TniB PF05621.11 GAX18098.1 - 0.094 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 GAX18098.1 - 0.096 12.7 0.1 9 6.3 0.1 2.7 1 1 1 2 2 2 0 Dynamin family Rad51 PF08423.11 GAX18099.1 - 2.1e-44 151.7 0.0 4.3e-44 150.7 0.0 1.4 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAX18099.1 - 1.2e-09 38.0 0.0 2.7e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 GAX18099.1 - 5.8e-06 25.8 0.1 3e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 GAX18099.1 - 0.0021 17.4 0.0 0.014 14.7 0.0 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 GAX18099.1 - 0.0055 16.2 0.1 0.49 9.8 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein MIase PF02426.16 GAX18099.1 - 0.11 12.7 0.1 22 5.3 0.1 2.6 2 0 0 2 2 2 0 Muconolactone delta-isomerase Vps8 PF12816.7 GAX18100.1 - 8.2e-46 156.0 0.8 5.2e-45 153.4 0.3 2.4 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 GAX18100.1 - 7.7e-06 25.8 0.8 4e-05 23.5 1.0 2.0 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.32 GAX18100.1 - 0.11 13.5 0.1 1.2 10.2 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Sulfotransfer_2 PF03567.14 GAX18101.1 - 2.8e-09 37.3 0.0 4.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family TPR_12 PF13424.6 GAX18102.1 - 0.00016 21.9 15.9 0.037 14.3 0.7 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat YlbD_coat PF14071.6 GAX18102.1 - 0.062 13.6 2.1 0.1 12.8 0.6 2.1 2 0 0 2 2 2 0 Putative coat protein TPR_2 PF07719.17 GAX18102.1 - 0.11 12.6 7.7 21 5.5 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18102.1 - 0.38 11.7 12.6 13 6.9 0.1 6.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX18102.1 - 0.45 11.1 10.9 7.9 7.1 0.2 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18102.1 - 1.5 9.5 12.8 4.2 8.1 1.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Acatn PF13000.7 GAX18103.1 - 8.3e-93 311.7 4.4 2.7e-72 244.0 0.4 3.4 1 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 RAMP4 PF06624.12 GAX18104.1 - 2.6e-15 56.2 0.2 2.8e-15 56.1 0.2 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Cyclin_N PF00134.23 GAX18105.1 - 1.7e-18 66.6 0.3 2.7e-18 65.9 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX18105.1 - 3.2e-06 27.2 1.0 6.6e-06 26.2 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain GATase_5 PF13507.6 GAX18106.1 - 1.1e-104 349.1 0.0 1.6e-104 348.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 GAX18106.1 - 1.3e-36 126.0 2.5 2.3e-20 73.3 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 GAX18106.1 - 2.1e-15 56.7 0.0 4.2e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 GAX18106.1 - 3.8e-12 46.5 0.0 1e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DnaJ PF00226.31 GAX18107.1 - 1.5e-19 69.9 0.0 2.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.13 GAX18108.1 - 3.2e-36 125.2 0.0 6.1e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAX18108.1 - 0.00053 18.9 0.0 0.00083 18.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 GAX18108.1 - 0.0035 18.0 0.2 0.0035 18.0 0.2 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Mon1 PF03164.14 GAX18108.1 - 0.022 13.8 0.8 0.039 13.0 0.8 1.3 1 0 0 1 1 1 0 Trafficking protein Mon1 Abhydrolase_2 PF02230.16 GAX18108.1 - 0.17 11.7 0.3 1.8 8.3 0.0 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase PGP_phosphatase PF09419.10 GAX18109.1 - 1.9e-42 144.7 0.0 2.5e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 GAX18109.1 - 5.8e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX18109.1 - 0.00097 19.5 0.1 1.6 9.0 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase MaoC_dehydratas PF01575.19 GAX18110.1 - 2.3e-14 53.0 0.0 4.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain Kinesin PF00225.23 GAX18111.1 - 3.7e-49 167.4 3.6 7.8e-49 166.4 3.6 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX18111.1 - 6.8e-08 32.6 0.2 1.5e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 GAX18111.1 - 0.0032 17.9 0.7 0.016 15.6 0.2 2.3 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 GAX18111.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 GAX18111.1 - 0.027 13.6 0.0 0.078 12.0 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein tRNA-synt_1c_C PF03950.18 GAX18112.1 - 0.018 14.9 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DUF2070 PF09843.9 GAX18112.1 - 0.25 9.6 0.0 0.36 9.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ARD PF03079.14 GAX18113.1 - 5e-44 150.3 0.2 7.9e-43 146.3 0.2 2.0 1 1 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.19 GAX18113.1 - 1.9e-08 34.3 0.1 3.5e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 GAX18113.1 - 4.3e-08 32.8 0.2 6.7e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GAX18113.1 - 4.6e-05 23.1 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Glyco_transf_11 PF01531.16 GAX18113.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 11 Cupin_3 PF05899.12 GAX18113.1 - 0.043 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pro_isomerase PF00160.21 GAX18114.1 - 1.9e-48 164.7 0.1 2e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MpPF26 PF07666.11 GAX18117.1 - 0.016 15.3 0.6 0.016 15.3 0.6 1.5 2 0 0 2 2 2 0 M penetrans paralogue family 26 Ion_trans_2 PF07885.16 GAX18118.1 - 0.0051 16.7 7.9 0.014 15.4 7.9 1.8 1 1 0 1 1 1 1 Ion channel SCAMP PF04144.13 GAX18118.1 - 2 8.7 9.3 3.5 7.9 9.3 1.3 1 0 0 1 1 1 0 SCAMP family Ion_trans_2 PF07885.16 GAX18119.1 - 0.00032 20.6 9.3 0.00053 19.9 8.9 1.5 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 GAX18119.1 - 0.0036 16.6 3.5 0.0051 16.1 3.5 1.2 1 0 0 1 1 1 1 Ion transport protein IRK_C PF17655.1 GAX18119.1 - 0.009 15.6 0.0 3.3 7.3 0.0 2.4 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain EPL1 PF10513.9 GAX18120.1 - 1.7e-09 38.3 0.5 3.8e-09 37.1 0.5 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like PUF PF00806.19 GAX18121.1 - 2.6e-44 146.4 1.1 1.1e-06 28.0 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat FliG_C PF01706.16 GAX18121.1 - 0.0031 17.7 0.3 0.017 15.3 0.1 2.1 2 0 0 2 2 2 1 FliG C-terminal domain Adenine_glyco PF03352.13 GAX18123.1 - 0.022 14.5 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase DUF445 PF04286.12 GAX18123.1 - 0.057 13.2 2.4 0.073 12.9 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1462 PF07315.11 GAX18124.1 - 0.085 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Ribosomal_L21p PF00829.21 GAX18126.1 - 6.3e-27 93.8 1.2 8.1e-27 93.4 1.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FAM60A PF15396.6 GAX18127.1 - 0.0079 16.2 16.6 0.0079 16.2 16.6 2.0 2 0 0 2 2 2 1 Protein Family FAM60A Hamartin PF04388.12 GAX18127.1 - 4.4 5.9 19.4 5.2 5.6 19.4 1.0 1 0 0 1 1 1 0 Hamartin protein HSP33 PF01430.19 GAX18128.1 - 5.6e-62 209.6 0.0 6.6e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein HTH_Tnp_Tc3_2 PF01498.18 GAX18128.1 - 0.24 11.7 0.6 8.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Transposase AAA_16 PF13191.6 GAX18129.1 - 7.4e-17 62.2 0.0 2.1e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 GAX18129.1 - 0.00059 18.9 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain ABC_tran PF00005.27 GAX18129.1 - 0.0049 17.4 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 GAX18129.1 - 0.0079 16.5 0.0 0.031 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.6 GAX18129.1 - 0.022 15.0 8.8 0.049 13.9 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Zeta_toxin PF06414.12 GAX18129.1 - 0.036 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NOD2_WH PF17779.1 GAX18129.1 - 0.085 13.2 1.1 0.5 10.7 0.3 2.5 2 0 0 2 2 2 0 NOD2 winged helix domain AAA_18 PF13238.6 GAX18129.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX18129.1 - 0.16 12.0 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Not1 PF04054.15 GAX18130.1 - 2.7e-126 421.4 0.3 6.3e-126 420.2 0.3 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAX18130.1 - 4e-82 274.9 0.0 1e-81 273.6 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 GAX18130.1 - 5.9e-68 227.8 1.1 1.2e-67 226.8 0.2 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 GAX18130.1 - 7.4e-63 210.9 4.0 7.4e-63 210.9 4.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 GAX18130.1 - 5.4e-07 29.8 0.0 1.7e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Myosin_head PF00063.21 GAX18131.1 - 4.3e-160 534.2 1.1 9e-160 533.1 1.1 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 GAX18131.1 - 0.025 14.9 0.0 0.025 14.9 0.0 3.6 4 1 1 5 5 5 0 AAA ATPase domain AAA_22 PF13401.6 GAX18131.1 - 0.026 14.8 3.5 0.28 11.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 GAX18131.1 - 0.027 14.6 8.5 0.84 9.7 5.8 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 GAX18131.1 - 0.039 14.3 0.4 0.65 10.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAX18131.1 - 0.04 13.2 1.4 0.11 11.7 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin ABC_tran PF00005.27 GAX18131.1 - 0.24 11.9 5.2 4.3 7.9 0.0 3.5 2 1 0 2 2 2 0 ABC transporter Phage_int_SAM_2 PF12834.7 GAX18131.1 - 0.54 11.0 3.9 14 6.4 0.3 3.5 2 0 0 2 2 2 0 Phage integrase, N-terminal DUF4407 PF14362.6 GAX18131.1 - 1.8 7.8 13.5 1.3 8.3 11.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 GAX18131.1 - 7.4 6.7 10.3 8 6.6 0.5 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Ank_5 PF13857.6 GAX18132.1 - 2.8e-11 43.4 1.7 9e-09 35.4 0.1 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX18132.1 - 3.7e-05 24.2 1.3 0.049 14.2 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Methyltransf_31 PF13847.6 GAX18133.1 - 2.6e-10 40.3 0.0 8e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX18133.1 - 6.4e-10 39.6 0.0 1.5e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX18133.1 - 7.2e-09 36.2 0.0 1.5e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX18133.1 - 1.2e-06 28.5 0.0 2.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX18133.1 - 1.4e-05 25.8 0.0 5e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GAX18133.1 - 0.036 12.6 0.0 5.5 5.4 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_16 PF13432.6 GAX18134.1 - 9.1e-12 45.4 5.7 0.00014 22.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18134.1 - 2.2e-11 42.9 5.3 0.00035 20.5 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18134.1 - 2.3e-11 43.5 0.5 0.0033 18.1 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX18134.1 - 2.8e-11 43.7 2.3 0.00028 21.3 0.0 4.4 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAX18134.1 - 7.8e-07 29.3 3.0 0.031 14.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18134.1 - 4.5e-06 26.4 3.8 1.3 9.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18134.1 - 1.4e-05 24.7 5.4 0.016 15.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18134.1 - 3.5e-05 23.4 2.2 1.1 9.1 0.1 4.4 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 GAX18134.1 - 4.8e-05 23.6 6.0 0.11 12.7 0.7 3.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX18134.1 - 0.00024 21.3 0.3 20 5.9 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX18134.1 - 0.002 18.3 0.5 4.5 7.6 0.0 3.2 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAX18134.1 - 0.009 16.0 2.3 3.3 7.9 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX18134.1 - 0.055 13.6 1.9 0.57 10.4 0.1 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat Cyclin_C_2 PF16899.5 GAX18134.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Cyclin C-terminal domain SLD5_C PF16922.5 GAX18135.1 - 0.015 15.5 0.1 0.069 13.3 0.1 2.1 1 1 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus GAS PF13851.6 GAX18136.1 - 1.8e-05 24.2 9.5 1.8e-05 24.2 9.5 9.1 2 2 5 8 8 8 4 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 GAX18136.1 - 0.00026 20.0 156.2 0.051 12.4 4.1 7.3 2 2 5 7 7 7 6 Spc7 kinetochore protein FapA PF03961.13 GAX18136.1 - 0.00027 19.7 0.6 0.00027 19.7 0.6 8.5 2 2 6 8 8 8 3 Flagellar Assembly Protein A Fez1 PF06818.15 GAX18136.1 - 0.00083 19.9 144.0 0.0021 18.6 20.6 8.0 1 1 5 7 7 7 3 Fez1 TPR_MLP1_2 PF07926.12 GAX18136.1 - 0.0018 18.4 4.8 0.0018 18.4 4.8 12.0 2 2 8 11 11 11 3 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 GAX18136.1 - 0.009 16.2 11.4 0.009 16.2 11.4 8.9 4 2 5 9 9 9 3 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 GAX18136.1 - 0.013 15.6 5.4 0.013 15.6 5.4 9.2 3 2 6 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 GAX18136.1 - 1.5 8.3 138.6 0.11 12.0 20.5 7.9 2 2 1 5 5 5 0 Intermediate filament protein TRCF PF03461.15 GAX18136.1 - 9.6 6.7 14.5 0.7 10.3 0.3 5.3 4 0 0 4 4 4 0 TRCF domain 2OG-FeII_Oxy_3 PF13640.6 GAX18137.1 - 6.9e-11 42.9 0.0 0.00026 21.8 0.0 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAX18137.1 - 3.2e-06 27.7 0.1 0.012 16.3 0.0 2.8 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.27 GAX18138.1 - 2.7e-35 120.2 1.5 6.5e-13 48.4 0.0 4.0 1 1 2 3 3 3 3 Mitochondrial carrier protein Vma12 PF11712.8 GAX18138.1 - 0.047 13.8 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CDT1_C PF16679.5 GAX18139.1 - 0.0051 17.2 6.4 0.0068 16.8 1.7 2.4 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Cas9_C PF18525.1 GAX18139.1 - 0.015 15.5 0.1 0.053 13.7 0.1 2.0 1 0 0 1 1 1 0 Cas9 C-terminal domain Patched PF02460.18 GAX18141.1 - 4.6e-09 35.0 6.2 4.6e-09 35.0 6.2 2.9 2 1 1 3 3 3 3 Patched family MMPL PF03176.15 GAX18141.1 - 9.4e-09 34.6 14.1 4e-07 29.3 1.3 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 GAX18141.1 - 8.2e-07 29.0 8.7 8.2e-07 29.0 8.7 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation QueF PF14489.6 GAX18141.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein Sterol-sensing PF12349.8 GAX18142.1 - 1e-08 35.2 10.7 1e-08 35.2 10.7 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAX18142.1 - 6.4e-08 31.2 9.2 6.4e-08 31.2 9.2 2.1 2 0 0 2 2 2 2 Patched family Peptidase_M3 PF01432.20 GAX18145.1 - 7.9e-138 460.5 0.0 1.1e-137 460.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 HSBP1 PF06825.12 GAX18145.1 - 0.0016 18.2 0.1 0.0047 16.8 0.1 1.8 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Peptidase_M50B PF13398.6 GAX18145.1 - 0.0058 16.3 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase M50B-like NrfD PF03916.14 GAX18147.1 - 0.15 11.6 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysulphide reductase, NrfD TPR_19 PF14559.6 GAX18148.1 - 6.5e-34 116.3 16.3 0.002 18.6 0.0 11.4 10 2 2 12 12 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18148.1 - 1.7e-31 106.2 25.2 0.0087 16.8 0.0 14.2 6 4 10 16 16 16 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18148.1 - 3.7e-31 104.7 12.8 0.014 15.5 0.0 14.4 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_17 PF13431.6 GAX18148.1 - 5.7e-24 82.7 18.4 0.022 15.1 0.0 13.9 16 0 0 16 16 14 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18148.1 - 1.2e-23 83.4 11.4 0.12 13.0 0.0 10.2 9 2 1 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAX18148.1 - 1.5e-18 66.9 28.4 0.033 14.5 0.4 12.2 11 3 2 13 13 13 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18148.1 - 1.8e-16 59.1 0.2 0.29 11.0 0.0 10.9 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18148.1 - 2.4e-16 58.5 8.0 0.33 11.3 0.0 11.9 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAX18148.1 - 1.3e-12 47.5 14.0 0.00093 18.5 0.5 6.1 1 1 5 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 GAX18148.1 - 2.5e-12 47.4 0.0 0.0017 18.4 0.0 5.9 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_9 PF13371.6 GAX18148.1 - 5e-09 36.2 16.2 0.015 15.4 0.1 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAX18148.1 - 1.3e-08 34.8 0.9 34 4.5 0.0 8.5 8 1 0 9 9 9 0 Mad3/BUB1 homology region 1 TPR_7 PF13176.6 GAX18148.1 - 9.7e-08 31.5 11.7 1.3 9.2 0.0 9.6 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18148.1 - 9.9e-08 31.5 10.6 2 8.1 0.1 8.5 6 3 3 9 9 9 2 TPR repeat TPR_6 PF13174.6 GAX18148.1 - 1.2e-06 28.8 17.7 5.6 7.8 0.0 10.6 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18148.1 - 8.8e-06 25.4 16.0 12 5.9 0.0 9.2 9 0 0 9 9 9 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GAX18148.1 - 0.00019 21.0 2.7 0.081 12.3 0.0 5.0 5 1 0 6 6 6 1 Coatomer epsilon subunit PerC PF06069.11 GAX18148.1 - 0.00042 20.5 0.1 0.017 15.3 0.0 3.0 2 0 0 2 2 2 1 PerC transcriptional activator ANAPC3 PF12895.7 GAX18148.1 - 0.0033 17.6 13.4 6.2 7.1 0.1 6.2 7 0 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 Rapsyn_N PF10579.9 GAX18148.1 - 0.0034 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 Rapsyn N-terminal myristoylation and linker region NARP1 PF12569.8 GAX18148.1 - 0.023 13.7 2.2 3.1 6.6 0.0 3.8 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 GAX18148.1 - 0.053 14.2 5.4 67 4.6 0.0 6.8 8 0 0 8 8 5 0 Tetratricopeptide repeat ATG16 PF08614.11 GAX18149.1 - 5.8e-09 36.5 130.3 6.1e-05 23.3 22.1 6.8 3 2 3 6 6 6 5 Autophagy protein 16 (ATG16) Rota_NSP4 PF01452.16 GAX18149.1 - 0.27 10.9 4.5 0.27 10.9 0.6 2.9 2 1 1 3 3 3 0 Rotavirus non structural protein GAS PF13851.6 GAX18149.1 - 0.44 9.9 113.9 0.24 10.7 23.8 7.6 2 2 3 7 7 7 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 GAX18149.1 - 3.7 7.3 78.8 0.32 10.8 4.6 7.6 5 2 3 8 8 8 0 Phage minor structural protein GP20 Fez1 PF06818.15 GAX18149.1 - 5.2 7.5 112.2 9.1 6.7 19.2 6.7 1 1 3 4 4 4 0 Fez1 Filament PF00038.21 GAX18149.1 - 7.3 6.1 110.4 3.8 7.0 8.5 7.8 1 1 5 6 6 6 0 Intermediate filament protein SET PF00856.28 GAX18150.1 - 6.8e-07 29.8 0.0 2.4e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 SET domain PAH PF02671.21 GAX18151.1 - 6e-36 122.3 11.3 1.5e-17 63.5 4.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAX18151.1 - 1.6e-33 114.6 0.1 4.9e-33 113.1 0.1 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 GAX18151.1 - 1.2e-19 71.2 0.1 7.4e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein Bac_globin PF01152.21 GAX18152.1 - 2e-19 69.9 0.3 1.2e-08 35.2 0.0 2.4 2 1 0 2 2 2 2 Bacterial-like globin Ribosomal_S10 PF00338.22 GAX18152.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e IF-2B PF01008.17 GAX18153.1 - 4.2e-61 206.6 0.0 5.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RNA_pol_Rpc4 PF05132.14 GAX18153.1 - 0.0029 18.1 5.8 0.011 16.1 4.7 2.1 2 0 0 2 2 2 1 RNA polymerase III RPC4 CCDC53 PF10152.9 GAX18153.1 - 7.6 6.9 9.1 15 6.0 9.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SARAF PF06682.12 GAX18154.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CD34_antigen PF06365.12 GAX18154.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SPW PF03779.14 GAX18154.1 - 0.96 9.1 9.2 0.17 11.5 2.2 2.2 2 0 0 2 2 2 0 SPW repeat RR_TM4-6 PF06459.12 GAX18155.1 - 0.033 14.0 4.3 0.045 13.6 4.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EF-hand_9 PF14658.6 GAX18155.1 - 0.088 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain TMEM132D_C PF15706.5 GAX18155.1 - 0.097 12.5 0.2 0.36 10.6 0.0 2.0 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PRIMA1 PF16101.5 GAX18155.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Rax2 PF12768.7 GAX18155.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SIT PF15330.6 GAX18155.1 - 0.36 11.3 2.6 26 5.3 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Nop14 PF04147.12 GAX18155.1 - 0.45 8.7 10.8 0.58 8.3 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 GAX18155.1 - 1.3 8.8 9.2 2 8.1 9.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.15 GAX18155.1 - 1.4 7.7 4.9 1.7 7.3 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NOA36 PF06524.12 GAX18155.1 - 1.4 8.2 10.0 2.1 7.6 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein CPSF100_C PF13299.6 GAX18155.1 - 1.4 9.1 4.6 2.4 8.3 4.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 GAX18155.1 - 1.5 8.4 8.3 52 3.5 10.0 2.2 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 GAX18155.1 - 2.2 6.9 5.5 3.8 6.2 5.5 1.3 1 0 0 1 1 1 0 Presenilin TMEM51 PF15345.6 GAX18155.1 - 3.2 7.5 5.7 1.3e+02 2.2 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 V_ATPase_I PF01496.19 GAX18155.1 - 4 5.2 5.0 64 1.2 7.8 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 GAX18155.1 - 6.7 7.1 8.6 12 6.3 8.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mito_carr PF00153.27 GAX18156.1 - 2.2e-25 88.4 0.8 3.2e-11 43.0 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA_Me_trans PF03054.16 GAX18157.1 - 3.6e-83 279.3 0.0 7e-83 278.3 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 GAX18157.1 - 0.00055 19.1 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 GAX18157.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 GAX18157.1 - 0.037 13.8 0.2 0.19 11.5 0.0 2.1 2 1 0 2 2 2 0 PP-loop family WW PF00397.26 GAX18158.1 - 2.5e-09 37.0 5.9 2.5e-09 37.0 5.9 2.1 2 0 0 2 2 2 1 WW domain DUF5541 PF17695.1 GAX18158.1 - 0.082 13.3 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5541) Biotin_lipoyl PF00364.22 GAX18159.1 - 1.5e-17 63.2 0.0 2.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAX18159.1 - 0.0028 17.4 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like QRPTase_N PF02749.16 GAX18159.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DEAD PF00270.29 GAX18160.1 - 1.5e-50 171.4 0.7 3.1e-50 170.4 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX18160.1 - 4.2e-30 104.4 0.1 3.1e-29 101.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX18160.1 - 0.0002 21.4 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX18160.1 - 0.00023 20.4 0.0 0.00048 19.4 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 GAX18160.1 - 0.07 13.4 3.6 0.18 12.1 1.4 2.7 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 GAX18160.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain SNF2_N PF00176.23 GAX18160.1 - 0.089 11.5 0.1 0.14 10.8 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DAGK_acc PF00609.19 GAX18161.1 - 8.4e-44 149.7 0.0 1.2e-42 145.9 0.0 2.3 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GAX18161.1 - 1.6e-21 76.2 0.0 3.6e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ANAPC15 PF15243.6 GAX18161.1 - 0.076 13.4 2.5 0.2 12.1 0.4 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Seryl_tRNA_N PF02403.22 GAX18162.1 - 0.0034 17.6 3.1 0.034 14.4 0.2 2.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DDE_Tnp_ISL3 PF01610.17 GAX18162.1 - 0.034 13.9 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 Transposase Smr PF01713.21 GAX18163.1 - 5.6e-09 36.2 0.5 1.1e-08 35.2 0.5 1.6 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 GAX18163.1 - 9.2e-06 25.5 2.4 9.2e-06 25.5 2.4 2.3 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 GAX18163.1 - 0.00072 20.2 3.8 0.002 18.8 3.8 1.6 1 1 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 GAX18163.1 - 0.0058 16.8 2.6 0.42 10.9 4.2 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 GAX18163.1 - 0.015 15.7 6.9 0.32 11.6 0.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GAX18163.1 - 0.022 14.7 2.3 0.022 14.7 2.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAX18163.1 - 4.9 7.1 13.3 0.39 10.6 4.0 2.7 2 1 0 2 2 2 0 CCCH-type zinc finger DUF2621 PF11084.8 GAX18164.1 - 0.12 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) STIMATE PF12400.8 GAX18165.1 - 2.1e-30 105.8 6.3 2.1e-30 105.8 6.3 1.6 2 0 0 2 2 2 1 STIMATE family ATPgrasp_ST PF14397.6 GAX18166.1 - 0.0064 15.8 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp PDZ_6 PF17820.1 GAX18167.1 - 3.6e-05 23.5 0.1 9e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX18167.1 - 0.00017 21.9 0.3 0.00047 20.4 0.3 1.7 1 0 0 1 1 1 1 PDZ domain PT PF04886.12 GAX18167.1 - 0.0015 18.0 14.3 0.0015 18.0 14.3 5.7 3 1 1 4 4 4 1 PT repeat PDZ_2 PF13180.6 GAX18167.1 - 0.076 13.3 0.6 0.21 12.0 0.6 1.7 1 0 0 1 1 1 0 PDZ domain DUF3629 PF12302.8 GAX18167.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) EssA PF10661.9 GAX18167.1 - 0.15 11.9 0.2 0.99 9.2 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA FixS PF03597.15 GAX18167.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type PPR_2 PF13041.6 GAX18168.1 - 2e-12 47.1 0.0 0.00064 19.9 0.0 8.0 8 1 2 10 10 10 1 PPR repeat family PPR PF01535.20 GAX18168.1 - 4.4e-08 32.8 6.2 0.055 13.7 0.1 6.9 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 GAX18168.1 - 1.5e-06 27.7 7.1 0.1 12.0 0.3 4.7 1 1 4 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GAX18168.1 - 0.00013 22.0 0.2 11 6.2 0.0 6.9 7 3 2 9 9 9 1 Pentatricopeptide repeat domain Wzy_C_2 PF11846.8 GAX18168.1 - 0.00026 21.0 0.7 0.001 19.0 0.1 2.3 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal MNE1 PF13762.6 GAX18168.1 - 0.00069 19.6 2.1 0.06 13.3 0.0 4.3 5 0 0 5 5 5 1 Mitochondrial splicing apparatus component Rab5-bind PF09311.11 GAX18168.1 - 0.031 13.7 0.5 0.071 12.5 0.5 1.5 1 0 0 1 1 1 0 Rabaptin-like protein BTAD PF03704.17 GAX18168.1 - 0.43 11.0 4.9 12 6.3 0.1 3.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Apo-CIII PF05778.12 GAX18168.1 - 2.3 7.9 6.1 7.9 6.2 0.4 3.3 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) TipAS PF07739.13 GAX18168.1 - 6.6 7.3 13.9 6 7.4 0.1 5.5 5 1 1 6 6 6 0 TipAS antibiotic-recognition domain UCH PF00443.29 GAX18169.1 - 3.4e-69 233.2 0.0 9.5e-69 231.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX18169.1 - 1e-16 61.5 0.0 2.4e-09 37.2 0.1 3.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAX18169.1 - 1.1e-13 51.6 0.0 5.8e-10 39.7 0.0 2.8 1 1 0 1 1 1 1 DUSP domain zf-MYND PF01753.18 GAX18169.1 - 1.3e-06 28.4 19.9 1.3e-06 28.4 19.9 3.1 3 0 0 3 3 3 1 MYND finger TPR_1 PF00515.28 GAX18169.1 - 7.3e-05 22.4 16.8 0.0014 18.3 0.9 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18169.1 - 0.0036 17.3 10.9 0.058 13.5 0.7 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX18169.1 - 0.048 14.0 5.4 1.4 9.2 0.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18169.1 - 3.1 8.3 8.6 1.3 9.4 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat UIM PF02809.20 GAX18174.1 - 0.055 13.4 4.5 0.24 11.4 4.5 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif Glyco_transf_49 PF13896.6 GAX18175.1 - 2.8e-35 122.3 0.5 8.6e-27 94.3 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Hemolysin_N PF12563.8 GAX18175.1 - 0.21 11.1 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Hemolytic toxin N terminal Peptidase_S24 PF00717.23 GAX18176.1 - 1.2e-07 31.5 0.0 3.7e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 GAX18176.1 - 7.2e-07 29.1 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Arv1 PF04161.13 GAX18177.1 - 1e-20 74.8 6.2 1e-20 74.8 6.2 1.5 1 1 0 1 1 1 1 Arv1-like family DZR PF12773.7 GAX18177.1 - 0.36 10.9 4.3 1.1 9.4 4.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon Fer2 PF00111.27 GAX18178.1 - 2.3e-06 27.5 0.1 4.2e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TerD PF02342.18 GAX18178.1 - 0.088 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 TerD domain EFG_II PF14492.6 GAX18179.1 - 0.023 14.8 3.7 4 7.6 0.3 3.2 3 0 0 3 3 3 0 Elongation Factor G, domain II DUF4816 PF16086.5 GAX18179.1 - 0.19 11.7 9.4 3 7.8 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4816) EBP50_C PF09007.11 GAX18179.1 - 8.3 7.4 7.4 10 7.1 0.4 3.0 3 0 0 3 3 3 0 EBP50, C-terminal GTP_cyclohydroI PF01227.22 GAX18180.1 - 3.6e-72 241.6 1.1 4.9e-72 241.1 1.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I DUF3776 PF12618.8 GAX18180.1 - 0.003 18.1 1.3 0.59 10.7 1.6 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3776) QueF PF14489.6 GAX18180.1 - 0.0087 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein PACT_coil_coil PF10495.9 GAX18180.1 - 0.066 13.8 0.2 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF1974 PF09317.11 GAX18180.1 - 0.18 11.3 0.5 0.37 10.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) NIF PF03031.18 GAX18181.1 - 5.6e-40 136.7 0.0 1e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.8 GAX18181.1 - 0.049 13.1 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) AIP3 PF03915.13 GAX18182.1 - 0.056 12.5 0.3 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Actin interacting protein 3 CLZ PF16526.5 GAX18182.1 - 0.13 12.7 0.3 8.4 6.8 0.1 2.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CDC37_C PF08564.10 GAX18183.1 - 4.9 7.3 8.1 41 4.4 8.1 2.6 1 1 0 1 1 1 0 Cdc37 C terminal domain PAP_fibrillin PF04755.12 GAX18184.1 - 0.0007 19.6 0.1 0.0066 16.4 0.0 2.0 2 0 0 2 2 2 1 PAP_fibrillin PMC2NT PF08066.12 GAX18184.1 - 0.14 12.8 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 PMC2NT (NUC016) domain GCIP PF13324.6 GAX18184.1 - 0.19 11.3 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Glyco_transf_24 PF18404.1 GAX18186.1 - 4.2e-138 459.2 3.9 7.4e-138 458.4 3.9 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 GAX18186.1 - 8.9e-29 101.2 0.0 1.2e-27 97.5 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 GAX18186.1 - 1.5e-15 57.3 0.0 4.2e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 GAX18186.1 - 3e-15 56.3 1.6 7.9e-15 55.0 0.3 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 GAX18186.1 - 1.1e-10 41.7 0.0 2.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 GAX18186.1 - 5.6e-10 39.2 0.1 1.9e-08 34.2 0.2 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 8 Pkinase PF00069.25 GAX18187.1 - 6.9e-19 68.2 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18187.1 - 3e-15 56.2 0.0 5.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 GAX18187.1 - 0.0077 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 ADH_zinc_N PF00107.26 GAX18189.1 - 1.6e-05 24.9 0.0 4.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TauE PF01925.19 GAX18190.1 - 3.9e-28 98.7 19.6 4.1e-15 56.1 0.1 2.7 3 1 0 3 3 3 2 Sulfite exporter TauE/SafE DUF1129 PF06570.11 GAX18190.1 - 0.27 10.7 9.6 0.92 8.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) GspL_C PF12693.7 GAX18190.1 - 0.29 11.0 0.9 0.45 10.4 0.1 1.6 2 0 0 2 2 2 0 GspL periplasmic domain LRR19-TM PF15176.6 GAX18190.1 - 0.5 10.4 1.4 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain PFK PF00365.20 GAX18192.1 - 6.1e-57 193.1 0.9 1.4e-56 192.0 0.2 1.8 2 0 0 2 2 2 1 Phosphofructokinase LSDAT_euk PF18139.1 GAX18192.1 - 0.016 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM DAGK_cat PF00781.24 GAX18192.1 - 0.097 12.3 0.4 0.67 9.6 0.1 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Plasmod_dom_1 PF09715.10 GAX18192.1 - 0.47 10.5 2.1 21 5.3 0.1 2.6 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Ribosomal_L11_N PF03946.14 GAX18195.1 - 1.5e-20 72.8 0.2 2.4e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GAX18195.1 - 1.1e-17 64.2 0.1 2.3e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain MCPVI PF02993.14 GAX18195.1 - 0.014 15.2 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Dus PF01207.17 GAX18196.1 - 8.4e-42 143.3 0.0 2.1e-39 135.4 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) SNF2_N PF00176.23 GAX18197.1 - 6.5e-52 176.4 0.9 1.2e-51 175.5 0.9 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX18197.1 - 7.3e-14 52.1 0.0 2.3e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 GAX18197.1 - 1.7e-11 44.0 0.2 4.7e-11 42.6 0.2 1.8 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 GAX18197.1 - 5.2e-11 42.8 0.1 3e-10 40.4 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RanBP PF00641.18 GAX18197.1 - 1.2e-09 37.3 19.5 1.4e-05 24.3 2.8 3.0 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DEAD PF00270.29 GAX18197.1 - 1.7e-08 34.5 0.0 5.9e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAX18197.1 - 0.0003 20.5 0.0 0.0024 17.6 0.0 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DZR PF12773.7 GAX18197.1 - 5.1 7.2 8.7 19 5.4 0.7 3.3 3 0 0 3 3 3 0 Double zinc ribbon PMM PF03332.13 GAX18198.1 - 3.9e-101 337.4 1.4 4.4e-101 337.2 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 GAX18198.1 - 4.9e-06 26.5 0.0 1.6e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ham1p_like PF01725.16 GAX18199.1 - 1.6e-42 145.5 0.0 1.9e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family UbiA PF01040.18 GAX18200.1 - 8.6e-31 107.1 19.4 1.2e-30 106.7 19.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_11 PF08241.12 GAX18201.1 - 2.1e-13 50.7 0.0 3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX18201.1 - 4.7e-11 43.3 0.0 7.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX18201.1 - 2.4e-09 37.1 0.0 5.8e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX18201.1 - 0.0076 17.0 0.0 0.022 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX18201.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain DUF21 PF01595.20 GAX18202.1 - 1.2e-27 96.7 1.1 1.9e-27 96.1 1.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Synaptobrevin PF00957.21 GAX18204.1 - 3.9e-15 55.4 0.4 6.5e-15 54.7 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAX18204.1 - 1.3e-10 41.1 0.0 3.1e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 GAX18204.1 - 0.019 14.7 0.1 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region 3Beta_HSD PF01073.19 GAX18205.1 - 0.039 12.9 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX18205.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein SRP54 PF00448.22 GAX18206.1 - 2.1e-60 203.7 0.4 3.4e-60 203.1 0.4 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GAX18206.1 - 2.9e-10 40.2 0.0 1.6e-09 37.9 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 GAX18206.1 - 0.00012 22.1 2.3 0.096 12.7 0.0 3.0 3 0 0 3 3 3 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 GAX18206.1 - 0.00016 21.9 1.7 0.00096 19.4 0.0 2.7 3 1 0 3 3 2 1 AAA domain SRP-alpha_N PF04086.13 GAX18206.1 - 0.00021 21.3 1.8 0.00035 20.6 1.8 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Zeta_toxin PF06414.12 GAX18206.1 - 0.00041 19.7 0.1 0.0021 17.4 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_33 PF13671.6 GAX18206.1 - 0.00058 20.0 0.1 0.0026 17.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX18206.1 - 0.0027 17.4 0.5 0.0062 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX18206.1 - 0.0092 16.4 2.1 0.079 13.3 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 GAX18206.1 - 0.0095 16.2 0.1 0.039 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAX18206.1 - 0.011 15.4 1.3 0.036 13.7 1.3 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 GAX18206.1 - 0.014 15.8 0.1 0.049 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 GAX18206.1 - 0.022 14.7 0.1 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 GAX18206.1 - 0.028 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 GAX18206.1 - 0.028 13.4 0.1 0.07 12.1 0.1 1.6 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 GAX18206.1 - 0.042 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX18206.1 - 0.077 12.9 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 NACHT domain HEAT_2 PF13646.6 GAX18206.1 - 0.081 13.3 1.0 1.3 9.4 0.0 2.9 3 0 0 3 3 2 0 HEAT repeats CutA1 PF03091.15 GAX18206.1 - 0.12 12.2 0.4 0.3 11.0 0.4 1.6 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein SDA1 PF05285.12 GAX18206.1 - 0.15 11.4 3.0 0.21 10.9 3.0 1.1 1 0 0 1 1 1 0 SDA1 AAA_31 PF13614.6 GAX18206.1 - 0.36 10.7 2.1 1 9.3 0.3 2.4 2 1 0 2 2 2 0 AAA domain MutS_V PF00488.21 GAX18208.1 - 2.8e-32 112.3 0.0 6.7e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain V Smr PF01713.21 GAX18208.1 - 1.2e-11 44.8 0.0 3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Smr domain AAA_21 PF13304.6 GAX18208.1 - 0.00036 20.4 0.0 0.13 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MutS_III PF05192.18 GAX18208.1 - 0.0017 18.6 0.0 0.0017 18.6 0.0 3.0 2 2 0 2 2 2 1 MutS domain III T2SSE PF00437.20 GAX18208.1 - 0.0072 15.4 0.6 0.026 13.6 0.1 2.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_23 PF13476.6 GAX18208.1 - 0.047 14.2 14.4 5.1 7.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain BLOC1_2 PF10046.9 GAX18208.1 - 0.12 12.7 8.9 0.041 14.2 3.2 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 GAX18208.1 - 0.15 10.9 18.7 0.03 13.2 14.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 GAX18208.1 - 1.6 7.8 8.0 3.8 6.5 8.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DnaJ_C PF01556.18 GAX18209.1 - 1.9e-38 131.8 3.3 3.6e-38 131.0 3.3 1.4 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX18209.1 - 3.8e-21 75.0 3.0 3.8e-21 75.0 3.0 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAX18209.1 - 2.7e-09 37.3 4.0 5.8e-09 36.2 4.0 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF5351 PF17302.2 GAX18209.1 - 0.097 12.9 3.1 4.8 7.4 1.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 GAX18209.1 - 0.39 10.7 3.1 1.8 8.6 3.1 2.1 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Per1 PF04080.13 GAX18210.1 - 0.17 11.7 3.3 0.27 10.9 3.3 1.3 1 0 0 1 1 1 0 Per1-like family DUF3522 PF12036.8 GAX18210.1 - 0.29 11.4 11.4 0.65 10.3 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) COX16 PF14138.6 GAX18211.1 - 0.08 13.5 0.0 0.08 13.5 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Pterin_4a PF01329.19 GAX18212.1 - 2.4e-24 85.3 0.7 3.1e-24 85.0 0.7 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ThylakoidFormat PF11264.8 GAX18213.1 - 4.3e-51 173.7 0.0 7.2e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Thylakoid formation protein Mur_ligase_M PF08245.12 GAX18214.1 - 2.9e-07 30.7 0.0 5.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 GAX18214.1 - 6.2e-07 29.6 0.0 5.8e-06 26.5 0.0 2.4 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Ald_Xan_dh_C2 PF02738.18 GAX18215.1 - 0.0072 14.8 0.3 0.3 9.5 0.1 2.1 2 0 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Varsurf_PPLC PF03490.13 GAX18216.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C FKBP_C PF00254.28 GAX18217.1 - 1.8e-21 76.2 0.0 3.2e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 GAX18217.1 - 0.0018 19.2 0.0 0.0049 17.8 0.0 1.7 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase COG6 PF06419.11 GAX18218.1 - 3.2e-56 190.8 15.6 6.7e-55 186.5 15.6 2.5 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 Exo70 PF03081.15 GAX18218.1 - 0.011 14.8 0.2 0.011 14.8 0.2 3.3 3 2 0 3 3 3 0 Exo70 exocyst complex subunit TIR_3 PF18567.1 GAX18218.1 - 0.056 13.4 0.2 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Toll/interleukin-1 receptor domain DUF1515 PF07439.11 GAX18218.1 - 0.28 11.2 4.0 11 6.1 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1515) DUF713 PF05218.14 GAX18218.1 - 0.34 10.6 3.9 9 6.0 0.4 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF713) CCDC117 PF15810.5 GAX18218.1 - 0.78 10.0 5.3 0.21 11.9 0.1 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 117 Chorein_N PF12624.7 GAX18219.1 - 3.3e-05 24.0 0.9 0.00016 21.7 0.4 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 DUF456 PF04306.13 GAX18219.1 - 0.97 9.7 6.8 0.079 13.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Sugar_tr PF00083.24 GAX18220.1 - 2e-84 284.1 11.9 2.4e-84 283.8 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX18220.1 - 6.1e-24 84.6 33.3 2.4e-18 66.2 8.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LPMO_10 PF03067.15 GAX18221.1 - 1.4e-28 100.9 1.1 1.9e-28 100.5 1.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Toxin_12 PF07740.12 GAX18221.1 - 0.0011 19.5 4.2 0.0027 18.4 4.2 1.7 1 0 0 1 1 1 1 Ion channel inhibitory toxin Mannitol_dh_C PF08125.13 GAX18222.1 - 1.7e-83 279.9 0.0 2.4e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 GAX18222.1 - 2.1e-37 128.6 0.0 3e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain GrpE PF01025.19 GAX18222.1 - 0.25 11.0 0.1 0.46 10.1 0.1 1.3 1 0 0 1 1 1 0 GrpE zf-MYND PF01753.18 GAX18224.1 - 2e-06 27.8 13.7 3.1e-06 27.2 13.7 1.3 1 0 0 1 1 1 1 MYND finger DBD_HTH PF18430.1 GAX18224.1 - 0.025 14.3 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain CCDC158 PF15921.5 GAX18224.1 - 0.13 10.0 0.2 0.18 9.6 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 PolC_DP2 PF03833.13 GAX18224.1 - 0.17 9.7 2.9 0.25 9.2 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Pribosyl_synth PF14572.6 GAX18225.1 - 2.7e-07 30.8 0.0 4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAX18225.1 - 1.1e-06 28.2 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FTR1 PF03239.14 GAX18226.1 - 3.7e-06 26.3 4.2 3.7e-06 26.3 4.2 2.5 2 1 0 2 2 2 1 Iron permease FTR1 family DUF4536 PF15055.6 GAX18226.1 - 0.096 12.9 0.4 0.31 11.3 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) DUF4418 PF14387.6 GAX18226.1 - 5.7 7.2 8.4 1.7 8.9 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) Pox_MCEL PF03291.16 GAX18227.1 - 1.4e-41 142.7 0.5 1.8e-20 73.3 0.0 3.2 3 0 0 3 3 3 3 mRNA capping enzyme Methyltransf_25 PF13649.6 GAX18227.1 - 7.9e-10 39.3 0.0 3.4e-05 24.5 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAX18227.1 - 6.1e-09 36.4 0.1 0.0097 16.5 0.0 3.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAX18227.1 - 9e-09 36.0 0.0 1.2e-06 29.2 0.0 3.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX18227.1 - 1.2e-08 34.9 0.0 1e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GAX18227.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX18227.1 - 0.033 13.5 0.1 5.4 6.3 0.1 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF563 PF04577.14 GAX18230.1 - 2e-15 57.5 0.0 3.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) ubiquitin PF00240.23 GAX18232.1 - 6.6e-29 99.5 0.0 1.3e-08 34.4 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 GAX18232.1 - 1.1e-22 79.6 0.1 8.9e-08 31.9 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Sod_Ni PF09055.11 GAX18232.1 - 9.7e-11 42.3 0.3 1.8e-10 41.5 0.3 1.4 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Ubiquitin_2 PF14560.6 GAX18232.1 - 1.5e-06 28.5 0.2 0.13 12.8 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX18232.1 - 0.0029 17.6 0.3 1.9 8.6 0.0 3.6 3 1 1 4 4 4 2 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX18232.1 - 0.042 13.8 0.1 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 GAX18233.1 - 6.3e-18 64.3 0.1 2.2e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Sod_Ni PF09055.11 GAX18233.1 - 9.9e-16 58.5 2.2 1.5e-15 57.9 2.2 1.2 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Rad60-SLD PF11976.8 GAX18233.1 - 1.7e-07 31.0 0.1 0.0091 15.8 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX18233.1 - 0.001 19.5 0.1 0.017 15.6 0.0 3.0 2 1 0 2 2 2 1 Ubiquitin-like domain YukD PF08817.10 GAX18233.1 - 0.02 15.6 0.1 2 9.2 0.1 2.4 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD FERM_f0 PF16511.5 GAX18233.1 - 0.055 13.8 0.0 4.5 7.6 0.0 3.3 2 1 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Sod_Ni PF09055.11 GAX18234.1 - 4.9e-05 23.9 0.4 5.8e-05 23.7 0.4 1.1 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase DUF1104 PF06518.11 GAX18234.1 - 0.064 13.6 0.4 0.13 12.6 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) ubiquitin PF00240.23 GAX18235.1 - 2.2e-20 72.1 0.0 4.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX18235.1 - 9.5e-09 35.0 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sod_Ni PF09055.11 GAX18235.1 - 1.7e-07 31.9 0.2 2.3e-07 31.4 0.2 1.1 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Ubiquitin_2 PF14560.6 GAX18235.1 - 0.11 13.0 0.0 0.46 11.0 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain RVT_1 PF00078.27 GAX18236.1 - 1.3e-06 28.1 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ubiquitin PF00240.23 GAX18237.1 - 2e-18 65.9 0.1 3.8e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX18237.1 - 1.2e-07 31.4 0.2 2e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Sod_Ni PF09055.11 GAX18237.1 - 2.2e-06 28.2 0.4 3.3e-06 27.7 0.4 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase TBK1_ULD PF18396.1 GAX18237.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 GAX18238.1 - 2.9e-23 81.4 0.2 3.8e-23 81.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX18238.1 - 3.8e-09 36.2 0.2 5e-09 35.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Dak1 PF02733.17 GAX18240.1 - 3.6e-103 344.7 2.4 3.6e-103 344.7 2.4 2.2 3 0 0 3 3 3 1 Dak1 domain Dak2 PF02734.17 GAX18240.1 - 1.1e-37 129.6 4.6 1.1e-37 129.6 4.6 2.3 3 0 0 3 3 3 1 DAK2 domain RPAP1_C PF08620.10 GAX18240.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 RPAP1-like, C-terminal Protamine_3 PF08188.11 GAX18241.1 - 0.019 15.2 0.8 0.037 14.2 0.8 1.5 1 0 0 1 1 1 0 Spermatozal protamine family UL16 PF17622.2 GAX18241.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral unique long protein 16 Cyclin_N PF00134.23 GAX18242.1 - 6.7e-15 55.0 0.1 1.2e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX18242.1 - 4.7e-06 26.7 0.6 4.7e-06 26.7 0.6 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain Acetyltransf_1 PF00583.25 GAX18243.1 - 3.2e-13 49.9 0.1 4.5e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX18243.1 - 8.8e-08 32.1 0.1 1.1e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX18243.1 - 1.1e-07 32.2 0.0 1.6e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX18243.1 - 6.4e-06 26.0 0.1 9.8e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAX18243.1 - 0.00032 20.8 0.3 0.00059 19.9 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAX18243.1 - 0.026 14.0 1.2 0.029 13.8 1.2 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase PanZ PF12568.8 GAX18243.1 - 0.031 14.0 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DUF2511 PF10709.9 GAX18243.1 - 0.098 12.9 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2511) Noelin-1 PF12308.8 GAX18245.1 - 0.03 14.3 0.2 0.03 14.3 0.2 1.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein bMG3 PF11974.8 GAX18246.1 - 1.2e-05 25.2 0.2 0.2 11.7 0.0 2.6 2 0 0 2 2 2 2 Bacterial alpha-2-macroglobulin MG3 domain Gmad2 PF10648.9 GAX18246.1 - 0.0025 18.0 0.3 0.39 11.0 0.1 2.8 2 0 0 2 2 2 1 Immunoglobulin-like domain of bacterial spore germination CarboxypepD_reg PF13620.6 GAX18246.1 - 0.0031 17.8 1.4 0.13 12.5 0.1 3.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 GAX18246.1 - 0.0056 16.9 8.2 0.51 10.6 0.1 3.6 3 0 0 3 3 3 2 SdrD B-like domain Big_6 PF17936.1 GAX18246.1 - 2.7 8.3 11.2 0.27 11.5 0.3 3.2 3 0 0 3 3 3 0 Bacterial Ig domain PDEase_I PF00233.19 GAX18247.1 - 1.4e-32 113.3 1.7 2.5e-32 112.5 1.7 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase YtzH PF14165.6 GAX18247.1 - 0.0028 18.0 0.4 0.32 11.4 0.2 2.6 2 0 0 2 2 2 2 YtzH-like protein DUF1240 PF06836.12 GAX18248.1 - 0.038 14.5 1.2 0.076 13.5 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) 2OG-FeII_Oxy_3 PF13640.6 GAX18249.1 - 2.9e-17 63.3 0.1 5.7e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 GAX18249.1 - 0.014 15.7 0.0 0.031 14.5 0.0 1.6 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy PF03171.20 GAX18249.1 - 0.022 15.2 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAX18249.1 - 0.028 15.1 0.0 0.075 13.7 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 GAX18249.1 - 0.072 12.2 0.0 0.092 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein DAO PF01266.24 GAX18250.1 - 2e-13 50.7 3.3 1.1e-06 28.5 0.3 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX18250.1 - 1.8e-09 37.3 0.1 1.1e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX18250.1 - 8.6e-09 35.0 1.0 2e-06 27.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 GAX18250.1 - 3.2e-07 29.9 0.1 8.3e-07 28.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAX18250.1 - 8.6e-07 28.0 0.1 2.7e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAX18250.1 - 1.4e-06 28.5 0.1 4.8e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAX18250.1 - 2.5e-06 27.0 0.3 5.2e-06 25.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX18250.1 - 5.1e-05 23.8 0.2 0.00059 20.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAX18250.1 - 0.00016 21.1 0.1 0.056 12.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 GAX18250.1 - 0.00032 20.0 0.3 0.0013 18.0 0.0 2.0 2 1 0 2 2 2 1 Thi4 family GIDA PF01134.22 GAX18250.1 - 0.00073 18.7 1.2 0.014 14.5 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAX18250.1 - 0.0014 17.8 0.8 0.0088 15.1 0.1 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.7 GAX18250.1 - 0.0068 15.8 0.2 0.017 14.5 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 GAX18250.1 - 0.0071 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 GAX18250.1 - 0.015 15.3 1.8 2.6 8.0 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 GAX18250.1 - 0.017 15.5 0.0 0.058 13.8 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF5527 PF17665.1 GAX18251.1 - 0.082 12.4 0.2 0.4 10.2 0.2 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DUF4211 PF13926.6 GAX18252.1 - 0.0034 17.4 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) EcoEI_R_C PF08463.10 GAX18252.1 - 0.057 13.5 0.1 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 EcoEI R protein C-terminal Polo_box_3 PF18544.1 GAX18252.1 - 0.092 13.4 0.0 0.16 12.7 0.0 1.3 1 0 0 1 1 1 0 Polo box domain Pyr_redox_2 PF07992.14 GAX18254.1 - 7.1e-37 127.2 0.0 3.8e-36 124.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX18254.1 - 0.00022 21.7 0.0 0.006 17.1 0.0 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GCV_T PF01571.21 GAX18255.1 - 0.023 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain PqiA PF04403.13 GAX18256.1 - 7.9e-15 55.0 15.1 3.3e-08 33.5 2.1 2.7 2 0 0 2 2 2 2 Paraquat-inducible protein A Aa_trans PF01490.18 GAX18257.1 - 9.4e-37 126.7 16.5 7.6e-36 123.7 16.5 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GST_N_2 PF13409.6 GAX18258.1 - 3.6e-15 56.0 0.0 9.6e-15 54.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAX18258.1 - 3.1e-05 24.1 0.2 8.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX18258.1 - 0.00048 20.3 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX18258.1 - 0.0005 20.0 0.1 0.0016 18.4 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX18258.1 - 0.15 12.5 0.0 7.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain HMG_box PF00505.19 GAX18259.1 - 2.5e-08 34.2 10.2 2.6e-08 34.1 6.1 3.1 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX18259.1 - 1.2e-07 32.2 3.1 1.2e-07 32.2 3.1 2.8 3 0 0 3 3 3 1 HMG-box domain DUF3987 PF13148.6 GAX18259.1 - 0.0074 15.3 4.7 0.0074 15.3 4.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) Mvb12 PF09452.10 GAX18260.1 - 0.15 12.5 1.0 0.84 10.1 0.0 2.3 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Orf78 PF06024.12 GAX18260.1 - 0.15 12.3 1.3 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) SDA1 PF05285.12 GAX18260.1 - 6.6 6.1 11.7 10 5.4 11.7 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GAX18260.1 - 7.5 4.6 10.2 11 4.0 10.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAX18260.1 - 8.4 4.6 7.3 12 4.0 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RFC1 PF08519.12 GAX18261.1 - 8.5e-38 130.0 0.0 2.4e-37 128.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 GAX18261.1 - 6.6e-15 55.7 0.6 1.7e-14 54.4 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 GAX18261.1 - 5.7e-10 39.4 0.0 2.1e-09 37.6 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 GAX18261.1 - 3.5e-07 30.3 0.1 3.5e-06 27.1 0.0 2.5 1 1 1 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 GAX18261.1 - 1.5e-05 25.1 0.0 4.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain PTCB-BRCT PF12738.7 GAX18261.1 - 2.6e-05 24.1 0.0 7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain AAA_16 PF13191.6 GAX18261.1 - 6.2e-05 23.4 0.0 0.00036 21.0 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain AAA_30 PF13604.6 GAX18261.1 - 0.00013 21.8 0.1 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAX18261.1 - 0.00029 20.6 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 GAX18261.1 - 0.0003 20.8 0.0 0.00093 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAX18261.1 - 0.0007 19.9 0.0 0.0024 18.2 0.0 2.0 1 1 0 1 1 1 1 RNA helicase AAA_assoc_2 PF16193.5 GAX18261.1 - 0.00089 19.6 0.1 0.0032 17.8 0.1 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 GAX18261.1 - 0.0013 19.0 1.4 0.012 15.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 GAX18261.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 GAX18261.1 - 0.0083 16.3 0.2 0.037 14.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 GAX18261.1 - 0.0094 15.9 0.4 0.51 10.2 0.1 2.4 1 1 1 2 2 2 1 NTPase DNA_pol3_delta PF06144.13 GAX18261.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_6 PF12774.7 GAX18261.1 - 0.04 12.9 0.0 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 GAX18261.1 - 0.049 13.6 0.0 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 GAX18261.1 - 0.1 12.0 0.0 0.92 8.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Viral_DNA_bi PF02236.17 GAX18261.1 - 0.11 12.7 0.1 0.99 9.6 0.0 2.5 2 1 0 2 2 2 0 Viral DNA-binding protein, all alpha domain AAA_18 PF13238.6 GAX18261.1 - 0.13 12.8 0.3 0.46 11.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain PSP1 PF04468.12 GAX18263.1 - 3.4e-31 107.4 1.3 5.3e-31 106.8 1.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region HAS-barrel PF09378.10 GAX18263.1 - 0.022 14.9 0.1 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 HAS barrel domain HCO3_cotransp PF00955.21 GAX18264.1 - 6e-117 391.6 8.6 9.1e-59 199.6 0.0 2.0 1 1 1 2 2 2 2 HCO3- transporter family ABC_membrane_2 PF06472.15 GAX18265.1 - 8.2e-56 189.4 9.2 1.2e-55 188.8 9.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAX18265.1 - 4.2e-19 69.4 0.1 1.1e-18 68.1 0.0 1.8 2 0 0 2 2 1 1 ABC transporter SbmA_BacA PF05992.12 GAX18265.1 - 4.3e-15 56.0 8.6 1.8e-14 53.9 8.5 1.9 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_16 PF13191.6 GAX18265.1 - 1.2e-05 25.7 0.1 8.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_membrane PF00664.23 GAX18265.1 - 2e-05 24.4 6.1 3.9e-05 23.5 6.1 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 GAX18265.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAX18265.1 - 0.0016 18.7 0.7 0.0087 16.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 GAX18265.1 - 0.0024 17.6 0.1 0.031 14.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAX18265.1 - 0.0026 17.5 0.3 0.0055 16.4 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 GAX18265.1 - 0.0031 17.1 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 GAX18265.1 - 0.0051 16.8 0.2 0.015 15.2 0.2 2.0 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 GAX18265.1 - 0.0052 16.5 0.1 0.26 11.0 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein TniB PF05621.11 GAX18265.1 - 0.0072 15.8 0.0 0.31 10.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_23 PF13476.6 GAX18265.1 - 0.015 15.8 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 GAX18265.1 - 0.016 14.6 0.0 0.086 12.3 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF815 PF05673.13 GAX18265.1 - 0.019 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 GAX18265.1 - 0.048 13.9 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 GAX18265.1 - 0.071 12.7 0.0 0.44 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX18265.1 - 0.078 13.5 0.6 0.75 10.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX18265.1 - 0.084 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAX18265.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAX18265.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX18265.1 - 0.12 12.3 0.5 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 GAX18265.1 - 0.14 12.3 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 GAX18265.1 - 0.14 11.5 0.3 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Peptidase_S49 PF01343.18 GAX18265.1 - 0.16 11.9 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 Gly_transf_sug PF04488.15 GAX18266.1 - 2.2e-08 34.6 0.0 6.2e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX18266.1 - 1.3e-06 28.0 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAX18267.1 - 4.8e-08 33.5 0.0 1.1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX18267.1 - 1.6e-06 27.8 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein KASH_CCD PF14662.6 GAX18268.1 - 0.00091 19.1 4.2 0.0013 18.6 4.2 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 GAX18268.1 - 0.00097 19.2 12.2 0.0015 18.6 12.2 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 GAX18268.1 - 0.0011 18.7 5.4 0.0013 18.3 5.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 GAX18268.1 - 0.0016 19.0 12.2 0.0024 18.4 12.2 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region BRE1 PF08647.11 GAX18268.1 - 0.0017 18.4 8.9 0.0017 18.4 8.9 1.5 2 0 0 2 2 1 1 BRE1 E3 ubiquitin ligase MbeD_MobD PF04899.12 GAX18268.1 - 0.0022 18.1 11.0 0.0022 18.1 11.0 2.1 2 0 0 2 2 2 1 MbeD/MobD like Exonuc_VII_L PF02601.15 GAX18268.1 - 0.0066 16.1 4.8 0.0079 15.8 4.8 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit Laminin_II PF06009.12 GAX18268.1 - 0.0085 16.1 4.2 0.0085 16.1 4.2 1.5 2 0 0 2 2 1 1 Laminin Domain II zf-CpG_bind_C PF12269.8 GAX18268.1 - 0.015 15.1 2.6 0.029 14.2 2.6 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain CENP-K PF11802.8 GAX18268.1 - 0.017 14.7 3.9 0.02 14.5 3.9 1.1 1 0 0 1 1 1 0 Centromere-associated protein K FapA PF03961.13 GAX18268.1 - 0.024 13.2 1.2 0.027 13.1 1.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A EzrA PF06160.12 GAX18268.1 - 0.03 12.5 7.4 0.039 12.1 7.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GTP-bdg_N PF13167.6 GAX18268.1 - 0.033 14.9 0.9 0.15 12.7 0.2 2.2 1 1 1 2 2 2 0 GTP-binding GTPase N-terminal DUF4472 PF14739.6 GAX18268.1 - 0.034 14.9 8.4 0.049 14.4 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) HemX PF04375.14 GAX18268.1 - 0.035 13.4 8.2 0.043 13.1 8.2 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMPIT PF07851.13 GAX18268.1 - 0.04 13.2 3.8 0.057 12.7 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cep57_CLD_2 PF14197.6 GAX18268.1 - 0.075 13.1 11.0 0.38 10.9 11.0 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 GAX18268.1 - 0.078 11.8 8.3 0.11 11.4 8.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LMBR1 PF04791.16 GAX18268.1 - 0.091 11.7 2.0 0.1 11.5 2.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1840 PF08895.11 GAX18268.1 - 0.095 13.0 1.1 0.17 12.3 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) GAS PF13851.6 GAX18268.1 - 0.1 11.9 11.9 0.28 10.5 12.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlgN PF05130.12 GAX18268.1 - 0.11 13.0 11.2 0.11 13.0 10.3 1.4 1 1 0 1 1 1 0 FlgN protein BLOC1_2 PF10046.9 GAX18268.1 - 0.12 12.7 6.1 0.19 12.1 5.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 THOC7 PF05615.13 GAX18268.1 - 0.12 12.7 9.7 0.25 11.6 9.7 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 V_ATPase_I PF01496.19 GAX18268.1 - 0.13 10.1 2.7 0.16 9.9 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 GAX18268.1 - 0.16 12.7 6.1 0.3 11.7 6.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF1204 PF06721.11 GAX18268.1 - 0.17 11.3 3.3 0.24 10.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) DUF2968 PF11180.8 GAX18268.1 - 0.17 11.5 14.8 0.24 11.0 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TMF_TATA_bd PF12325.8 GAX18268.1 - 0.22 11.8 11.9 0.28 11.4 3.0 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ACCA PF03255.14 GAX18268.1 - 0.24 11.3 5.3 0.33 10.8 4.4 1.6 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PspB PF06667.12 GAX18268.1 - 0.27 11.3 6.0 2.1 8.5 5.5 2.3 1 1 1 2 2 2 0 Phage shock protein B DUF1635 PF07795.11 GAX18268.1 - 0.28 11.0 7.1 0.47 10.3 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4763 PF15960.5 GAX18268.1 - 0.28 10.4 13.7 0.25 10.6 12.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) DUF4201 PF13870.6 GAX18268.1 - 0.53 10.0 13.0 1.1 9.0 10.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Snapin_Pallidin PF14712.6 GAX18268.1 - 0.55 10.7 11.1 1.2 9.6 11.0 1.4 1 1 0 1 1 1 0 Snapin/Pallidin DUF1664 PF07889.12 GAX18268.1 - 0.79 9.8 6.0 1.5 8.9 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FUSC PF04632.12 GAX18268.1 - 1.3 7.4 4.4 1.6 7.2 4.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prefoldin PF02996.17 GAX18268.1 - 1.8 8.5 11.4 0.31 11.0 3.9 2.5 2 1 1 3 3 3 0 Prefoldin subunit BMFP PF04380.13 GAX18268.1 - 1.8 9.1 9.6 39 4.8 7.4 2.8 2 1 0 2 2 2 0 Membrane fusogenic activity OmpH PF03938.14 GAX18268.1 - 1.9 8.9 14.8 6.1 7.2 14.8 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 GAX18268.1 - 1.9 7.8 9.9 4 6.7 9.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 GAX18268.1 - 2.1 8.8 9.1 1.2e+02 3.2 9.1 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 GAX18268.1 - 2.1 8.8 10.7 1.1 9.7 4.2 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 GAX18268.1 - 2.5 7.9 17.1 0.26 11.1 2.0 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 GAX18268.1 - 2.6 7.3 14.6 4 6.7 14.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HAUS6_N PF14661.6 GAX18268.1 - 2.7 7.5 9.3 6.4 6.3 9.3 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cnn_1N PF07989.11 GAX18268.1 - 5.1 7.3 9.8 27 5.0 9.7 2.1 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 GAX18268.1 - 6.5 7.4 20.2 2.6 8.7 9.7 3.0 1 1 2 3 3 3 0 SlyX Retrotrans_gag PF03732.17 GAX18268.1 - 7.4 6.9 8.7 17 5.7 6.3 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein PPR_2 PF13041.6 GAX18270.1 - 1.4e-17 63.6 0.4 7.4e-06 26.1 0.0 6.1 4 1 2 6 6 6 4 PPR repeat family PPR_3 PF13812.6 GAX18270.1 - 3.2e-16 59.2 0.0 1.3e-08 34.8 0.0 4.4 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 GAX18270.1 - 8.2e-08 32.0 2.9 4 7.9 0.0 6.6 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 GAX18270.1 - 6.6e-07 28.9 3.3 0.39 10.5 0.0 5.3 5 0 0 5 5 5 3 PPR repeat SAP PF02037.27 GAX18270.1 - 1.7e-05 24.4 1.4 9.8e-05 22.0 1.3 2.2 2 0 0 2 2 2 1 SAP domain DUF2614 PF11023.8 GAX18271.1 - 0.021 14.9 0.7 0.036 14.2 0.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain IBR PF01485.21 GAX18272.1 - 1.8e-19 69.7 40.9 2.6e-10 40.4 6.0 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GAX18272.1 - 1.6e-06 28.0 4.2 1.6e-06 28.0 4.2 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX18272.1 - 2.7e-06 27.6 6.2 2.7e-06 27.6 6.2 4.2 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 GAX18272.1 - 4.4e-05 23.3 5.0 4.4e-05 23.3 5.0 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX18272.1 - 7.7e-05 22.5 6.0 7.7e-05 22.5 6.0 5.1 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX18272.1 - 0.00019 21.4 4.6 0.00019 21.4 4.6 4.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAX18272.1 - 0.0029 17.3 3.0 0.0029 17.3 3.0 4.5 4 1 1 5 5 5 1 RING-like zinc finger zf-RING_4 PF14570.6 GAX18272.1 - 0.96 9.3 31.9 0.16 11.8 4.9 3.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-piccolo PF05715.13 GAX18272.1 - 2 8.6 26.1 2.1 8.6 4.2 3.6 3 0 0 3 3 3 0 Piccolo Zn-finger Vir_act_alpha_C PF10400.9 GAX18272.1 - 2.6 8.8 8.5 4.5 8.0 2.1 2.9 3 0 0 3 3 3 0 Virulence activator alpha C-term Palm_thioest PF02089.15 GAX18273.1 - 2.3e-59 201.1 0.1 3e-59 200.8 0.1 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase SNARE_assoc PF09335.11 GAX18276.1 - 0.0043 17.5 7.8 0.1 13.1 4.9 2.9 1 1 1 2 2 2 2 SNARE associated Golgi protein Glycophorin_A PF01102.18 GAX18276.1 - 0.28 11.4 2.9 6.1 7.1 0.0 2.5 3 0 0 3 3 3 0 Glycophorin A AAA_16 PF13191.6 GAX18278.1 - 5.1e-17 62.8 3.2 6.1e-17 62.5 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAX18278.1 - 0.00053 20.3 0.1 0.0064 16.8 0.0 2.8 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 GAX18278.1 - 0.0039 16.4 0.1 4.4 6.4 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain AAA_18 PF13238.6 GAX18278.1 - 0.011 16.2 0.0 0.032 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAX18278.1 - 0.018 14.3 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 GAX18278.1 - 0.074 13.0 0.9 0.8 9.6 0.9 2.6 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 GAX18278.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 GAX18278.1 - 0.15 11.4 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 KaiC TPR_2 PF07719.17 GAX18278.1 - 0.17 12.1 1.1 2.4 8.5 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Atx10homo_assoc PF09759.9 GAX18279.1 - 3e-07 30.4 0.9 0.015 15.3 0.0 2.5 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 GAX18279.1 - 0.00046 20.2 0.9 0.0014 18.6 0.5 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.23 GAX18279.1 - 0.0017 18.3 2.8 4.2 7.5 0.1 3.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 GAX18279.1 - 0.0059 15.7 0.1 0.013 14.5 0.1 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term 7tm_3 PF00003.22 GAX18280.1 - 3.8e-40 138.1 15.3 4.9e-40 137.7 15.3 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX18280.1 - 9.7e-16 58.1 0.0 6.2e-15 55.5 0.0 2.1 1 1 0 1 1 1 1 Periplasmic binding protein domain zf-Tim10_DDP PF02953.15 GAX18281.1 - 7.7e-12 44.7 0.2 1.2e-11 44.1 0.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PAS_9 PF13426.7 GAX18282.1 - 3.2e-07 30.6 0.0 5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 GAX18282.1 - 6.9e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_12 PF18095.1 GAX18282.1 - 0.02 14.6 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 UPF0242 C-terminal PAS-like domain PAS_4 PF08448.10 GAX18282.1 - 0.048 13.9 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 GAX18282.1 - 0.075 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain Thioredoxin PF00085.20 GAX18283.1 - 6.6e-11 42.1 0.2 2.3e-10 40.4 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX18283.1 - 0.046 14.1 0.0 0.27 11.6 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like HTH_10 PF04967.12 GAX18283.1 - 0.13 12.1 0.1 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 HTH DNA binding domain Thioredoxin_2 PF13098.6 GAX18283.1 - 0.32 11.5 0.0 0.32 11.5 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain DUF1823 PF08853.11 GAX18284.1 - 1.2e-41 141.5 0.4 1.2e-41 141.5 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1823) PAP_assoc PF03828.19 GAX18285.1 - 1.8e-09 37.7 0.1 3.8e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAX18285.1 - 9.6e-05 22.6 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAX18285.1 - 0.00069 19.7 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_fibrillin PF04755.12 GAX18286.1 - 2.2e-15 57.1 0.1 2e-14 54.0 0.1 2.2 1 1 0 1 1 1 1 PAP_fibrillin DDHD PF02862.17 GAX18286.1 - 0.051 13.7 1.7 0.069 13.3 1.7 1.3 1 0 0 1 1 1 0 DDHD domain DUF4629 PF15442.6 GAX18286.1 - 1.4 9.1 13.5 3.2 8.0 13.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4629) DUF2981 PF11200.8 GAX18286.1 - 6.8 6.3 8.2 10 5.8 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Ank_2 PF12796.7 GAX18287.1 - 9.1e-06 26.2 0.0 2.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX18287.1 - 0.0021 18.6 0.0 1.4 9.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX18287.1 - 0.0085 16.4 0.1 0.31 11.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX18287.1 - 0.018 15.5 0.0 1 10.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 GAX18287.1 - 0.17 12.4 0.0 8.2 7.1 0.0 3.1 2 1 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 GAX18288.1 - 1e-192 638.1 0.0 9.1e-68 228.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18288.1 - 1.2e-78 264.0 0.0 3.3e-28 98.7 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 GAX18288.1 - 4.1e-14 52.6 0.0 0.0039 16.6 0.0 4.8 5 1 0 5 5 5 3 Kinase-like Pkinase_fungal PF17667.1 GAX18288.1 - 3.8e-09 35.8 0.0 0.00033 19.5 0.0 2.8 3 0 0 3 3 3 2 Fungal protein kinase Kdo PF06293.14 GAX18288.1 - 6.7e-06 25.6 0.2 0.017 14.5 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 GAX18288.1 - 0.0073 15.3 0.8 1.6 7.6 0.1 2.2 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase APH PF01636.23 GAX18288.1 - 0.068 13.1 0.2 12 5.8 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX18288.1 - 0.13 11.8 0.1 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase GTP_cyclohydro2 PF00925.20 GAX18290.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II Gaa1 PF04114.14 GAX18291.1 - 9.2e-24 84.3 8.0 2.8e-22 79.4 8.0 2.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component DGF-1_C PF11040.8 GAX18292.1 - 0.034 14.2 0.8 0.19 11.8 0.8 2.3 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus MMtag PF10159.9 GAX18292.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.8 5 0 0 5 5 5 0 Multiple myeloma tumor-associated PIG-P PF08510.12 GAX18293.1 - 3.1e-10 40.0 0.6 4.4e-10 39.5 0.6 1.2 1 0 0 1 1 1 1 PIG-P DUF3149 PF11346.8 GAX18293.1 - 0.08 12.6 0.6 0.16 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Mito_carr PF00153.27 GAX18295.1 - 1.9e-49 165.5 4.6 8e-18 64.2 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 GAX18296.1 - 0.00034 20.4 0.1 1.5 8.5 0.0 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Toxin_38 PF14866.6 GAX18296.1 - 0.045 14.1 0.6 0.098 13.0 0.6 1.5 1 0 0 1 1 1 0 Potassium channel toxin Aa_trans PF01490.18 GAX18297.1 - 2.9e-30 105.3 21.5 3.8e-30 104.9 21.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2976 PF11190.8 GAX18297.1 - 0.6 9.9 0.0 0.6 9.9 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) EMP24_GP25L PF01105.24 GAX18298.1 - 9.8e-12 45.2 0.4 3.4e-11 43.4 0.4 1.8 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GrpE PF01025.19 GAX18298.1 - 0.72 9.5 4.0 0.2 11.3 0.4 1.7 2 0 0 2 2 2 0 GrpE MBOAT PF03062.19 GAX18300.1 - 8.3e-27 94.4 30.0 1.2e-26 94.0 30.0 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PH PF00169.29 GAX18300.1 - 5.4e-08 33.3 0.0 1.5e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 GAX18300.1 - 0.0054 17.1 0.0 0.043 14.2 0.0 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain MBOAT_2 PF13813.6 GAX18300.1 - 0.0056 16.9 8.4 0.017 15.4 8.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PH_13 PF16652.5 GAX18300.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain CBM_6 PF03422.15 GAX18301.1 - 4.9e-42 143.2 0.1 6.6e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX18301.1 - 1.3e-33 116.7 5.9 2e-33 116.0 5.9 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX18301.1 - 1.1e-16 61.0 1.2 5.3e-07 29.8 0.2 2.5 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX18301.1 - 0.00025 21.3 0.2 0.0013 19.0 0.1 2.2 2 0 0 2 2 2 1 Carbohydrate binding module (family 35) CopC PF04234.12 GAX18301.1 - 0.0041 18.1 0.2 1.1 10.4 0.0 3.2 3 0 0 3 3 3 1 CopC domain MAPEG PF01124.18 GAX18302.1 - 0.00034 20.5 1.1 0.00056 19.8 1.1 1.5 1 1 0 1 1 1 1 MAPEG family EMC3_TMCO1 PF01956.16 GAX18302.1 - 0.069 12.9 1.0 0.085 12.6 1.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Myb_DNA-binding PF00249.31 GAX18304.1 - 7e-20 71.0 0.5 2.8e-12 46.6 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX18304.1 - 1.2e-15 57.5 0.3 7.5e-10 38.9 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX18304.1 - 2e-05 24.4 0.1 0.024 14.5 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 GAX18304.1 - 0.019 15.3 7.8 0.32 11.4 0.1 3.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain LBR_tudor PF09465.10 GAX18304.1 - 0.044 13.6 0.1 0.085 12.7 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DSHCT PF08148.12 GAX18307.1 - 1.8e-54 183.8 0.7 3.4e-54 182.9 0.7 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 GAX18307.1 - 6.4e-24 85.3 0.0 2.5e-23 83.4 0.0 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 GAX18307.1 - 1.1e-18 67.6 0.1 3.9e-18 65.8 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX18307.1 - 5.2e-06 26.8 0.0 3.5e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAX18307.1 - 0.0014 18.9 0.1 0.1 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Ski2_N PF17911.1 GAX18307.1 - 0.036 13.9 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Ski2 N-terminal region PhoH PF02562.16 GAX18307.1 - 0.16 11.4 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein YL1 PF05764.13 GAX18307.1 - 5.3 7.1 11.8 18 5.4 11.8 2.0 1 0 0 1 1 1 0 YL1 nuclear protein zf-RING_2 PF13639.6 GAX18308.1 - 1.8e-12 47.4 4.9 1.8e-12 47.4 4.9 3.4 3 1 1 4 4 3 1 Ring finger domain zf-RING_11 PF17123.5 GAX18308.1 - 3.8e-11 42.5 1.8 3.8e-11 42.5 1.8 2.9 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX18308.1 - 3.1e-09 36.5 5.0 3.1e-09 36.5 5.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX18308.1 - 1.2e-08 34.7 3.6 1.2e-08 34.7 3.6 2.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX18308.1 - 1.4e-06 28.2 2.4 1.4e-06 28.2 2.4 2.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAX18308.1 - 2.9e-06 27.5 6.0 2.9e-06 27.5 6.0 2.7 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RanBP PF00641.18 GAX18308.1 - 4.5e-05 22.7 1.0 4.5e-05 22.7 1.0 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_3 PF13920.6 GAX18308.1 - 4.8e-05 23.1 2.8 4.8e-05 23.1 2.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX18308.1 - 0.00016 21.5 3.1 0.00016 21.5 3.1 2.9 3 0 0 3 3 3 1 zinc-RING finger domain DUF5518 PF17647.1 GAX18308.1 - 0.00065 19.8 1.3 0.0011 19.2 1.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5518) DNA_RNApol_7kD PF03604.13 GAX18308.1 - 0.011 15.3 0.1 0.04 13.6 0.1 2.0 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_4 PF14447.6 GAX18308.1 - 0.012 15.5 3.8 0.012 15.5 3.8 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX18308.1 - 0.024 14.7 2.0 0.024 14.7 2.0 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Gly-zipper_YMGG PF13441.6 GAX18308.1 - 0.061 13.1 6.7 0.11 12.2 6.7 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 GAX18308.1 - 0.1 12.6 7.7 0.2 11.7 7.7 1.4 1 0 0 1 1 1 0 Glycine zipper FANCL_C PF11793.8 GAX18308.1 - 0.51 10.6 8.1 2.8 8.2 5.0 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain FYDLN_acid PF09538.10 GAX18308.1 - 0.73 10.5 4.8 1.9 9.2 4.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PRP21_like_P PF12230.8 GAX18308.1 - 2.5 7.9 4.7 15 5.3 0.1 2.4 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein DZR PF12773.7 GAX18308.1 - 3.4 7.8 11.8 9.4 6.4 0.7 3.4 3 0 0 3 3 3 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 GAX18308.1 - 3.5 7.3 15.7 0.26 11.0 3.8 2.9 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAX18308.1 - 4.3 7.5 9.9 1.2 9.3 4.0 2.7 2 1 0 2 2 2 0 RING-variant domain OrfB_Zn_ribbon PF07282.11 GAX18308.1 - 7.1 6.6 7.7 5.1 7.1 0.6 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Anoctamin PF04547.12 GAX18309.1 - 2.9e-104 349.4 3.5 3.6e-104 349.1 3.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel HTH_57 PF18679.1 GAX18309.1 - 0.13 12.6 0.1 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 ThcOx helix turn helix domain PDZ PF00595.24 GAX18310.1 - 2.3e-05 24.7 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX18310.1 - 0.0037 17.5 0.0 0.011 16.1 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX18310.1 - 0.022 14.6 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 PDZ domain BCDHK_Adom3 PF10436.9 GAX18311.1 - 5.5e-28 97.8 0.0 7.7e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAX18311.1 - 5.3e-11 43.0 0.0 9.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX18311.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAX18311.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HAD_2 PF13419.6 GAX18313.1 - 2.4e-08 34.3 0.0 4.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAX18313.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 GAX18313.1 - 0.03 14.0 0.1 0.73 9.5 0.1 2.2 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.6 GAX18313.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Lactamase_B_2 PF12706.7 GAX18314.1 - 6.2e-05 22.6 3.0 0.0008 19.0 3.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX18314.1 - 0.00014 21.9 0.6 0.00031 20.8 0.3 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily TPR_12 PF13424.6 GAX18315.1 - 2.9e-20 72.3 0.3 1.4e-09 38.1 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18315.1 - 2.6e-15 55.7 0.8 6e-05 22.8 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18315.1 - 9.2e-09 34.8 2.2 0.12 12.5 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18315.1 - 2.5e-08 33.4 1.6 0.069 13.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18315.1 - 1.3e-07 31.2 0.4 0.025 14.2 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 GAX18315.1 - 1.5e-07 31.0 0.9 0.25 11.5 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18315.1 - 0.004 17.2 2.5 1.8 9.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18315.1 - 0.34 11.9 7.2 14 6.9 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CAF1 PF04857.20 GAX18316.1 - 6.7e-72 242.4 0.0 8.3e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease R3H PF01424.22 GAX18316.1 - 0.051 13.6 0.0 0.21 11.6 0.0 2.0 1 0 0 1 1 1 0 R3H domain Cullin PF00888.22 GAX18317.1 - 7.6e-194 645.8 6.6 9.1e-194 645.5 6.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAX18317.1 - 9.6e-28 96.0 2.1 1.2e-27 95.7 0.7 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain EMP24_GP25L PF01105.24 GAX18318.1 - 5.1e-16 59.1 0.0 7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Chloroa_b-bind PF00504.21 GAX18319.1 - 3.5e-35 121.9 0.1 5.8e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ATP-grasp_2 PF08442.10 GAX18320.1 - 0.18 11.3 0.7 0.24 10.9 0.7 1.2 1 0 0 1 1 1 0 ATP-grasp domain Thioredoxin PF00085.20 GAX18321.1 - 4.5e-07 29.8 0.0 9.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAX18321.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family XdhC_C PF13478.6 GAX18321.1 - 0.019 15.5 0.0 0.05 14.1 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain Glyco_trans_4_4 PF13579.6 GAX18321.1 - 0.039 14.4 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain NAD_binding_7 PF13241.6 GAX18321.1 - 0.055 13.9 0.0 0.17 12.4 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 GAX18321.1 - 0.071 13.7 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.26 GAX18322.1 - 0.00016 22.2 0.0 0.00038 20.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Omega-toxin PF06357.11 GAX18322.1 - 0.6 9.9 2.1 1.4 8.8 2.1 1.6 1 0 0 1 1 1 0 Omega-atracotoxin HATPase_c PF02518.26 GAX18323.1 - 6.1e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cons_hypoth95 PF03602.15 GAX18324.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Eco57I PF07669.11 GAX18324.1 - 0.039 14.4 0.3 0.088 13.3 0.3 1.6 1 1 0 1 1 1 0 Eco57I restriction-modification methylase K-cyclin_vir_C PF09080.10 GAX18325.1 - 0.086 13.3 2.0 0.11 12.9 2.0 1.1 1 0 0 1 1 1 0 K cyclin, C terminal eIF-3_zeta PF05091.12 GAX18326.1 - 2.7e-163 544.7 0.0 3.1e-163 544.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 GAX18326.1 - 0.11 12.1 0.4 0.36 10.3 0.0 2.1 3 0 0 3 3 3 0 NMDA receptor-regulated gene protein 2 C-terminus Vac7 PF12751.7 GAX18326.1 - 0.19 11.1 3.0 0.31 10.4 3.0 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 UCH PF00443.29 GAX18327.1 - 9.5e-46 156.4 0.0 1.9e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX18327.1 - 3.5e-17 63.0 0.0 1.1e-16 61.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Acyl-CoA_ox_N PF14749.6 GAX18327.1 - 0.096 13.2 0.7 0.2 12.2 0.7 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal IFP_35_N PF07334.13 GAX18327.1 - 0.1 12.7 6.7 0.12 12.4 4.8 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIC PF04977.15 GAX18327.1 - 0.1 12.4 0.7 0.26 11.1 0.7 1.6 1 0 0 1 1 1 0 Septum formation initiator zf-H2C2_2 PF13465.6 GAX18327.1 - 0.66 10.5 2.3 39 4.9 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain NP1-WLL PF11733.8 GAX18328.1 - 0.66 9.7 2.5 1 9.1 2.5 1.2 1 0 0 1 1 1 0 Non-capsid protein NP1 EphA2_TM PF14575.6 GAX18329.1 - 0.16 12.9 0.2 1.9 9.4 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain BSD PF03909.17 GAX18330.1 - 1.9e-13 50.2 0.3 1.9e-13 50.2 0.3 3.8 3 0 0 3 3 3 1 BSD domain HisKA_2 PF07568.12 GAX18330.1 - 0.32 11.1 3.4 0.35 11.0 0.9 2.5 2 1 0 2 2 2 0 Histidine kinase MitMem_reg PF13012.6 GAX18330.1 - 0.55 10.7 6.8 2.3 8.7 6.3 2.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function NOA36 PF06524.12 GAX18330.1 - 0.61 9.4 8.3 1.9 7.8 8.3 1.8 1 0 0 1 1 1 0 NOA36 protein Rb_C PF08934.10 GAX18330.1 - 4.2 7.1 7.7 1.4 8.7 2.4 2.5 2 0 0 2 2 2 0 Rb C-terminal domain Baculo_PEP_C PF04513.12 GAX18330.1 - 4.3 7.4 20.3 3.6 7.6 7.7 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acyl-CoA_dh_2 PF08028.11 GAX18330.1 - 8.5 6.7 6.8 16 5.8 2.8 2.6 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain PUB PF09409.10 GAX18331.1 - 1.2e-06 28.4 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 PUB domain PDZ PF00595.24 GAX18331.1 - 0.00083 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX18331.1 - 0.0015 18.3 0.1 0.0075 16.1 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX18331.1 - 0.006 16.9 0.2 0.017 15.4 0.0 1.8 2 0 0 2 2 2 1 PDZ domain DUF4855 PF16147.5 GAX18331.1 - 0.018 14.2 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) HAD_SAK_2 PF18143.1 GAX18333.1 - 8.2e-23 81.3 0.0 9.5e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins GWT1 PF06423.12 GAX18334.1 - 8.5e-20 71.4 8.8 8.5e-20 71.4 8.8 3.2 3 1 0 3 3 3 1 GWT1 Leader_CPA1 PF08252.11 GAX18334.1 - 0.36 10.3 1.7 1.1 8.7 1.7 1.8 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide DUF4383 PF14325.6 GAX18334.1 - 1.3 9.4 12.2 0.029 14.7 3.7 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4383) BCDHK_Adom3 PF10436.9 GAX18335.1 - 8.4e-37 126.5 0.1 1.3e-36 125.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAX18335.1 - 4.6e-14 52.9 0.0 9.7e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX18335.1 - 6.3e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec20 PF03908.13 GAX18336.1 - 0.17 11.8 0.1 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Sec20 Caveolin PF01146.17 GAX18336.1 - 0.5 10.3 1.8 0.63 10.0 0.6 1.7 2 0 0 2 2 2 0 Caveolin GMC_oxred_N PF00732.19 GAX18337.1 - 3.8e-40 138.1 0.0 5.6e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAX18337.1 - 1.1e-25 90.8 0.0 1.9e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAX18337.1 - 4.9e-05 22.5 0.2 7.5e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAX18337.1 - 0.00085 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAX18337.1 - 0.0025 17.1 0.0 0.0082 15.4 0.0 1.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX18337.1 - 0.0069 15.3 0.1 0.0097 14.8 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 GAX18337.1 - 0.014 14.7 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX18337.1 - 0.029 13.1 0.2 0.065 11.9 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 GAX18337.1 - 0.041 14.1 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX18337.1 - 0.054 13.1 0.3 0.12 11.9 0.2 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX18337.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAX18337.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TRAM_LAG1_CLN8 PF03798.16 GAX18338.1 - 2.5e-24 86.1 25.1 2.5e-24 86.1 25.1 2.6 2 1 0 2 2 2 1 TLC domain SLC3A2_N PF16028.5 GAX18338.1 - 1.5 8.4 4.2 0.94 9.1 0.1 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Sec7 PF01369.20 GAX18339.1 - 9.7e-60 201.4 0.0 2e-59 200.3 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAX18339.1 - 1.9e-36 125.3 2.6 1.9e-36 125.3 2.6 3.3 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAX18339.1 - 1.4e-28 98.6 0.4 7.1e-27 93.1 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DCB PF16213.5 GAX18339.1 - 2e-11 43.9 3.8 3.6e-10 39.8 1.0 3.1 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Arm PF00514.23 GAX18339.1 - 0.12 12.4 0.1 0.58 10.3 0.1 2.3 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Tic22 PF04278.12 GAX18340.1 - 1.2e-07 31.4 0.0 7e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Tic22-like family Nnf1 PF03980.14 GAX18340.1 - 0.018 15.4 0.3 0.055 13.9 0.3 1.8 1 0 0 1 1 1 0 Nnf1 DUF3327 PF11806.8 GAX18340.1 - 0.044 14.5 0.0 0.23 12.2 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3327) DUF2630 PF10944.8 GAX18340.1 - 0.06 13.8 0.7 0.14 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Nop14 PF04147.12 GAX18342.1 - 8.4e-136 454.4 40.4 1e-135 454.2 40.4 1.0 1 0 0 1 1 1 1 Nop14-like family TUDOR_5 PF18359.1 GAX18342.1 - 0.00015 21.4 0.4 0.00036 20.2 0.4 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 GAX18342.1 - 0.0011 19.4 0.1 0.0041 17.6 0.1 2.1 1 0 0 1 1 1 1 Agenet domain DUF4399 PF14347.6 GAX18342.1 - 0.087 13.2 0.5 0.21 12.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Biopterin_H PF00351.21 GAX18343.1 - 4e-99 331.8 0.2 5.4e-99 331.4 0.2 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 GAX18343.1 - 5.6e-05 22.8 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GAX18343.1 - 0.17 12.5 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 ACT domain JUPITER PF17054.5 GAX18345.1 - 0.024 14.2 0.4 0.11 12.0 0.0 2.0 1 1 0 2 2 2 0 Microtubule-Associated protein Jupiter PAH PF02671.21 GAX18346.1 - 5.1e-39 132.2 4.9 1e-19 70.4 2.6 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAX18346.1 - 3.7e-18 65.4 0.5 1e-17 64.0 0.5 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 GAX18346.1 - 0.07 12.8 1.5 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of Sin3a protein CHASE3 PF05227.13 GAX18346.1 - 8.2 6.3 13.4 0.028 14.3 2.3 2.4 3 0 0 3 3 3 0 CHASE3 domain NifU PF01106.17 GAX18347.1 - 4.1e-27 94.1 0.6 2.8e-21 75.4 0.4 2.2 2 0 0 2 2 2 2 NifU-like domain COP-gamma_platf PF08752.10 GAX18348.1 - 9.2e-08 32.3 0.0 1.3e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Vps39_2 PF10367.9 GAX18348.1 - 0.00029 21.2 0.1 0.0007 20.0 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF1517 PF07466.11 GAX18350.1 - 5e-45 153.9 2.7 6.3e-45 153.6 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) DUF2749 PF10907.8 GAX18350.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) Aph-1 PF06105.12 GAX18351.1 - 6e-24 84.7 10.2 3.4e-23 82.3 10.2 1.9 1 1 0 1 1 1 1 Aph-1 protein Ribosomal_L22e PF01776.17 GAX18352.1 - 0.014 15.8 1.4 0.014 15.8 1.4 1.8 2 0 0 2 2 2 0 Ribosomal L22e protein family CCDC92 PF14916.6 GAX18352.1 - 0.032 14.0 3.5 0.13 12.0 3.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain of unknown function PTS-HPr PF00381.19 GAX18352.1 - 0.047 13.9 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 PTS HPr component phosphorylation site Vps35 PF03635.17 GAX18352.1 - 0.23 9.9 8.0 0.1 11.1 3.9 2.0 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 35 Vicilin_N PF04702.12 GAX18352.1 - 3.7 7.4 10.0 5.5 6.8 1.3 2.3 2 0 0 2 2 2 0 Vicilin N terminal region RasGAP_C PF03836.15 GAX18352.1 - 4 7.6 14.1 0.67 10.1 6.1 2.5 2 0 0 2 2 2 0 RasGAP C-terminus Sas6_CC PF18594.1 GAX18352.1 - 4.2 7.2 6.5 0.93 9.3 1.7 2.4 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain FUSC PF04632.12 GAX18352.1 - 4.3 5.7 4.1 6.6 5.1 4.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.8 GAX18352.1 - 8.7 6.4 21.9 1.7 8.7 8.2 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TNFR_c6 PF00020.18 GAX18353.1 - 0.42 11.0 24.6 0.38 11.2 1.5 4.3 3 1 0 3 3 3 0 TNFR/NGFR cysteine-rich region SnoaL PF07366.12 GAX18354.1 - 2.9e-27 95.0 0.0 3.8e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAX18354.1 - 2.8e-13 50.4 0.0 4.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain PSII_Pbs31 PF18240.1 GAX18355.1 - 2e-37 127.5 10.1 4.5e-37 126.4 10.1 1.6 1 0 0 1 1 1 1 Photosystem II Psb31 protein HrpE PF06188.12 GAX18357.1 - 0.2 11.5 0.0 14 5.5 0.0 2.2 2 0 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E MerC PF03203.14 GAX18359.1 - 9.3e-20 71.2 11.7 1.8e-19 70.3 11.7 1.5 1 0 0 1 1 1 1 MerC mercury resistance protein DUF4281 PF14108.6 GAX18360.1 - 6.2e-20 71.8 0.3 7.1e-20 71.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) SNF2_N PF00176.23 GAX18361.1 - 4.3e-53 180.3 0.0 7.3e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX18361.1 - 1.3e-14 54.4 0.0 3.1e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX18361.1 - 1.7e-11 44.4 0.0 6.7e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAX18361.1 - 4.7e-06 26.0 0.9 6.9e-05 22.2 0.1 2.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAX18361.1 - 7.6e-06 25.8 0.1 2.2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAX18361.1 - 0.0091 15.7 0.0 0.024 14.3 0.0 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 GAX18361.1 - 0.11 11.3 0.0 0.38 9.6 0.0 1.8 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 HD_2 PF12917.7 GAX18361.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Rhodanese PF00581.20 GAX18363.1 - 4.4e-08 33.6 0.0 6.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 GAX18364.1 - 7.3e-65 218.9 0.0 8.6e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18364.1 - 2.3e-28 99.2 0.0 2.9e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX18364.1 - 0.00034 20.6 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX18364.1 - 0.25 10.7 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ALG3 PF05208.13 GAX18365.1 - 1.1e-123 413.2 16.1 1.4e-123 412.9 16.1 1.1 1 0 0 1 1 1 1 ALG3 protein PALP PF00291.25 GAX18366.1 - 3.5e-64 217.0 1.4 4e-64 216.8 1.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 GAX18366.1 - 0.007 16.3 0.2 0.026 14.5 0.2 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Dymeclin PF09742.9 GAX18367.1 - 2.3e-168 561.5 0.0 2.6e-168 561.3 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 GAX18367.1 - 4.5e-165 551.0 0.0 7.8e-140 467.6 0.0 2.1 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Ferric_reduct PF01794.19 GAX18368.1 - 1.6e-14 54.1 11.9 1.6e-14 54.1 11.9 2.4 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAX18368.1 - 5e-12 46.2 0.0 1.6e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 GAX18368.1 - 1.6 9.3 18.4 1.1 9.9 1.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) YuiB PF14068.6 GAX18368.1 - 6.7 7.4 8.5 8 7.1 2.5 3.3 2 1 1 3 3 3 0 Putative membrane protein Ferric_reduct PF01794.19 GAX18369.1 - 8.7e-16 58.2 10.3 8.7e-16 58.2 10.3 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAX18369.1 - 1.2e-10 41.7 0.0 5.6e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAX18370.1 - 1.1e-14 54.7 9.8 1.1e-14 54.7 9.8 2.9 3 1 1 4 4 4 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAX18370.1 - 2.6e-11 43.9 0.0 6.3e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NodZ PF05830.11 GAX18372.1 - 1.2e-11 44.0 0.0 1.9e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) ABC1 PF03109.16 GAX18373.1 - 3.8e-20 72.2 0.0 3.1e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 GAX18373.1 - 0.00025 20.5 0.0 0.00099 18.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pox_ser-thr_kin PF05445.11 GAX18373.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 GAX18373.1 - 0.25 11.2 3.2 0.19 11.6 1.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Acyltransferase PF01553.21 GAX18374.1 - 7.5e-14 51.5 0.0 3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Orf78 PF06024.12 GAX18374.1 - 0.072 13.4 3.4 8.5 6.7 0.0 3.6 4 0 0 4 4 4 0 Orf78 (ac78) MFS_3 PF05977.13 GAX18374.1 - 0.14 10.5 2.3 0.22 9.9 2.3 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector DUF5383 PF17355.2 GAX18374.1 - 0.2 12.1 0.9 0.68 10.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Zip PF02535.22 GAX18376.1 - 2.5e-19 69.7 14.2 3.5e-18 65.9 14.2 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter MAP17 PF15807.5 GAX18376.1 - 0.069 13.4 0.8 0.35 11.1 0.3 2.3 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EI24 PF07264.11 GAX18376.1 - 9.2 6.5 10.4 4.8 7.4 0.1 3.1 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) Sulfotransfer_3 PF13469.6 GAX18378.1 - 0.0024 18.3 2.5 0.0024 18.3 2.5 3.3 2 1 0 2 2 2 1 Sulfotransferase family DDHD PF02862.17 GAX18378.1 - 0.058 13.5 3.4 5.1 7.2 0.0 2.2 2 0 0 2 2 2 0 DDHD domain Erv26 PF04148.13 GAX18378.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 TCP PF03634.13 GAX18378.1 - 0.23 12.0 8.5 1.2 9.6 0.2 2.4 2 0 0 2 2 2 0 TCP family transcription factor SID-1_RNA_chan PF13965.6 GAX18378.1 - 0.26 9.7 2.8 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Zip PF02535.22 GAX18378.1 - 0.66 9.1 9.4 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4834 PF16118.5 GAX18378.1 - 0.91 10.5 12.1 0.47 11.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) YABBY PF04690.13 GAX18378.1 - 3.4 8.2 6.4 1 9.9 0.2 2.2 2 0 0 2 2 2 0 YABBY protein Connexin PF00029.19 GAX18378.1 - 5.5 6.7 11.5 15 5.2 0.2 2.3 2 0 0 2 2 2 0 Connexin RNA_pol_3_Rpc31 PF11705.8 GAX18378.1 - 6.7 6.9 26.9 0.047 13.9 16.3 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PPL5 PF18168.1 GAX18378.1 - 7.7 5.7 14.4 1.2 8.4 0.4 2.2 2 0 0 2 2 2 0 Prim-pol family 5 CLN3 PF02487.17 GAX18378.1 - 9.4 5.2 10.2 1.3 8.0 0.2 2.1 2 0 0 2 2 2 0 CLN3 protein Ribosomal_S28e PF01200.18 GAX18379.1 - 2.2e-32 110.9 1.3 2.4e-32 110.7 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DUF3850 PF12961.7 GAX18379.1 - 0.19 11.8 0.0 2.3 8.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3850) RusA PF05866.11 GAX18380.1 - 8.7e-15 55.4 0.0 1.8e-14 54.3 0.0 1.5 2 0 0 2 2 2 1 Endodeoxyribonuclease RusA GvpD PF07088.11 GAX18380.1 - 0.086 11.4 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein Sld5 PF05916.11 GAX18381.1 - 5e-16 59.1 0.7 7.8e-16 58.5 0.3 1.5 2 0 0 2 2 2 1 GINS complex protein zf-TAZ PF02135.16 GAX18384.1 - 1.9e-09 37.8 9.5 1.9e-09 37.8 9.5 2.1 2 0 0 2 2 2 1 TAZ zinc finger VP_N-CPKC PF11475.8 GAX18384.1 - 0.078 12.9 0.3 0.28 11.1 0.3 1.9 1 0 0 1 1 1 0 Virion protein N terminal domain DUF4035 PF13227.6 GAX18384.1 - 0.083 12.6 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Sigma70_r2 PF04542.14 GAX18385.1 - 1.1e-19 69.9 0.0 2.3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GAX18385.1 - 1.2e-16 60.0 5.9 1.3e-16 59.8 0.6 3.4 4 0 0 4 4 4 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 GAX18385.1 - 5.6e-11 42.4 4.9 4.3e-09 36.3 1.2 2.8 2 0 0 2 2 2 2 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 GAX18385.1 - 1.1e-05 25.3 0.0 3.7e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 HNH_repeat PF18780.1 GAX18385.1 - 0.048 13.5 1.2 0.18 11.7 0.0 2.5 2 0 0 2 2 2 0 Homing endonuclease repeat DUF3323 PF11796.8 GAX18385.1 - 0.35 10.7 2.8 0.75 9.7 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Transketolase_N PF00456.21 GAX18386.1 - 7.3e-149 495.3 0.0 1.4e-148 494.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAX18386.1 - 5.6e-45 153.2 0.0 2.5e-44 151.1 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX18386.1 - 2.5e-06 27.4 0.0 1e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAX18386.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Terpene_synth PF01397.21 GAX18386.1 - 0.0095 15.6 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 Terpene synthase, N-terminal domain TPP_enzyme_C PF02775.21 GAX18386.1 - 0.053 13.3 0.0 0.4 10.5 0.0 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Yip1 PF04893.17 GAX18387.1 - 3.5e-10 39.9 17.8 9e-10 38.5 17.8 1.8 1 1 0 1 1 1 1 Yip1 domain Fer4_24 PF18109.1 GAX18387.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain BaffR-Tall_bind PF09256.10 GAX18388.1 - 0.93 9.3 3.1 4.1 7.3 1.1 2.2 1 1 1 2 2 2 0 BAFF-R, TALL-1 binding tRNA-synt_1b PF00579.25 GAX18389.1 - 1.6e-17 63.8 0.0 5.4e-17 62.0 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) MOSC PF03473.17 GAX18389.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 MOSC domain ERG2_Sigma1R PF04622.12 GAX18389.1 - 0.14 11.5 0.0 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein PAS_9 PF13426.7 GAX18390.1 - 2.9e-07 30.7 0.0 1.2e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain bZIP_1 PF00170.21 GAX18390.1 - 6.5e-06 26.2 4.3 1.9e-05 24.7 4.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor PAS_8 PF13188.7 GAX18390.1 - 0.00063 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 GAX18390.1 - 0.0012 18.8 4.4 0.0012 18.8 4.4 2.4 2 0 0 2 2 2 1 Basic region leucine zipper PAS PF00989.25 GAX18390.1 - 0.0077 16.2 0.0 0.0077 16.2 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 GAX18390.1 - 0.037 14.3 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold Myb_DNA-bind_5 PF13873.6 GAX18390.1 - 0.048 13.7 0.0 0.58 10.3 0.0 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain BBL5 PF07289.11 GAX18390.1 - 0.19 10.8 5.1 0.43 9.6 5.1 1.6 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein DUF3591 PF12157.8 GAX18391.1 - 1.7e-57 195.1 0.0 1.1e-42 146.3 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 GAX18391.1 - 1.8e-20 72.8 0.0 4.5e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain BLOC1_2 PF10046.9 GAX18391.1 - 0.63 10.4 4.2 2.5 8.5 0.3 3.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mito_carr PF00153.27 GAX18392.1 - 6e-64 212.0 5.0 1.5e-22 79.3 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2205 PF10224.9 GAX18392.1 - 0.11 12.5 0.3 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 Short coiled-coil protein gag_pre-integrs PF13976.6 GAX18394.1 - 0.00021 21.1 0.1 0.00088 19.1 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain FlaC_arch PF05377.11 GAX18394.1 - 0.22 11.9 2.9 0.66 10.4 0.2 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 GAX18394.1 - 0.26 11.3 2.8 18 5.4 0.1 2.6 2 0 0 2 2 2 0 FlxA-like protein HTH_42 PF06224.12 GAX18395.1 - 0.22 11.0 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain HemolysinCabind PF00353.19 GAX18396.1 - 7.3e-14 51.4 251.5 1e-06 28.6 12.2 23.2 22 3 3 25 25 25 12 RTX calcium-binding nonapeptide repeat (4 copies) PhyH PF05721.13 GAX18397.1 - 5.3e-41 141.2 0.1 8.6e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAX18397.1 - 0.026 14.9 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF285 PF03382.14 GAX18398.1 - 1.4e-26 92.7 0.1 1.7e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 Pyrid_oxidase_2 PF13883.6 GAX18399.1 - 6.6e-42 143.3 0.0 1.3e-21 77.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase 3HCDH_RFF PF18321.1 GAX18401.1 - 0.076 13.5 0.0 15 6.1 0.0 2.8 1 1 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain PT PF04886.12 GAX18402.1 - 5.9e-05 22.5 17.6 5.9e-05 22.5 17.6 10.6 5 4 2 7 7 7 2 PT repeat MTCP1 PF08991.10 GAX18403.1 - 0.054 13.7 6.8 0.1 12.8 6.8 1.6 1 1 0 1 1 1 0 Mature-T-Cell Proliferation I type Multi_Drug_Res PF00893.19 GAX18405.1 - 8.9e-15 55.1 2.8 8.9e-15 55.1 2.8 1.7 2 0 0 2 2 2 1 Small Multidrug Resistance protein EamA PF00892.20 GAX18405.1 - 0.0022 18.2 7.4 0.0022 18.2 7.4 1.7 2 0 0 2 2 2 1 EamA-like transporter family JUPITER PF17054.5 GAX18405.1 - 0.16 11.4 0.1 0.22 11.0 0.1 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter CPSase_L_D2 PF02786.17 GAX18406.1 - 5.8e-69 231.8 0.0 1.4e-68 230.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 GAX18406.1 - 6.1e-67 225.2 0.0 1.1e-66 224.3 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 GAX18406.1 - 1.3e-35 122.2 0.7 1.2e-34 119.2 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAX18406.1 - 1.8e-32 111.7 0.0 6.4e-32 109.9 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 GAX18406.1 - 1.9e-28 99.8 0.0 3.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 GAX18406.1 - 6e-18 64.4 5.0 8.4e-18 64.0 2.9 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAX18406.1 - 1.3e-13 50.5 0.5 7e-06 25.8 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAX18406.1 - 6.1e-11 42.2 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 GAX18406.1 - 4.7e-07 30.5 1.2 0.086 13.5 0.0 3.5 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp PF02222.22 GAX18406.1 - 6.9e-07 29.0 0.0 2.3e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 GAX18406.1 - 9.8e-07 28.2 0.3 0.017 14.4 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 GAX18406.1 - 0.00021 21.4 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 GAX18406.1 - 0.0012 18.8 0.4 0.0033 17.4 0.4 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 GAX18406.1 - 0.0051 16.3 0.2 0.0092 15.4 0.2 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HK97-gp10_like PF04883.12 GAX18406.1 - 0.01 16.8 0.1 0.6 11.1 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component PTS_EIIA_1 PF00358.20 GAX18406.1 - 0.011 15.4 0.2 0.3 10.8 0.1 2.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ATP-grasp_4 PF13535.6 GAX18406.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain TTL PF03133.15 GAX18406.1 - 0.022 13.9 0.0 0.051 12.7 0.0 1.5 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family PYNP_C PF07831.13 GAX18406.1 - 0.1 12.3 0.2 0.69 9.6 0.0 2.3 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF285 PF03382.14 GAX18407.1 - 4.1e-87 288.0 38.9 5.4e-33 113.3 5.2 3.0 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 DrrA_P4M PF14860.6 GAX18407.1 - 0.096 12.5 0.5 8.9 6.2 0.1 3.4 2 1 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain U5_2-snRNA_bdg PF10597.9 GAX18407.1 - 1 9.4 8.4 35 4.5 0.1 4.5 1 1 5 6 6 6 0 U5-snRNA binding site 2 of PrP8 DUF285 PF03382.14 GAX18408.1 - 1.6e-94 312.0 38.8 2.1e-35 121.1 5.1 3.0 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 Guanylate_cyc PF00211.20 GAX18409.1 - 1.1e-43 149.0 0.0 2.1e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX18409.1 - 2.5e-33 115.8 3.4 5.4e-33 114.7 3.4 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 GAX18409.1 - 0.0042 17.1 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 CHASE domain PX PF00787.24 GAX18412.1 - 8.5e-17 61.2 0.0 2.7e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 PX domain DUF4366 PF14283.6 GAX18412.1 - 0.22 11.6 6.0 0.061 13.4 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Sec62 PF03839.16 GAX18412.1 - 0.62 9.5 5.6 1.4 8.4 5.6 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1764 PF08576.10 GAX18412.1 - 0.99 10.3 8.9 0.51 11.3 4.6 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) EIIBC-GUT_N PF03612.14 GAX18412.1 - 1.6 8.4 7.7 6.7 6.4 7.7 2.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Baculo_PP31 PF05311.11 GAX18412.1 - 4.4 6.7 10.1 11 5.4 10.1 1.6 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) HAUS6_N PF14661.6 GAX18412.1 - 8.2 5.9 14.2 0.44 10.1 6.4 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.6 GAX18412.1 - 9 5.6 21.9 0.38 10.0 14.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Snf7 PF03357.21 GAX18413.1 - 1.3e-10 41.2 12.6 1.6e-10 40.9 12.6 1.1 1 0 0 1 1 1 1 Snf7 DUF1771 PF08590.10 GAX18413.1 - 0.0064 16.8 4.8 0.011 16.1 4.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DMSP_lyase PF16867.5 GAX18413.1 - 0.24 11.0 1.2 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase PsbP PF01789.16 GAX18416.1 - 9.3e-21 74.6 0.0 1.3e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 PsbP Na_Pi_cotrans PF02690.15 GAX18417.1 - 1.2e-38 132.4 25.2 3.3e-21 75.8 9.3 2.4 2 0 0 2 2 2 2 Na+/Pi-cotransporter zf-LITAF-like PF10601.9 GAX18417.1 - 0.54 10.6 3.4 4.3 7.7 0.0 3.6 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF4611 PF15387.6 GAX18417.1 - 9.6 6.5 11.3 3.5 7.9 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Na_Pi_cotrans PF02690.15 GAX18419.1 - 1.7e-36 125.4 31.8 9.1e-22 77.7 9.2 2.7 2 1 0 2 2 2 2 Na+/Pi-cotransporter Toxin_35 PF10530.9 GAX18422.1 - 0.0011 18.9 1.9 0.0011 18.9 1.9 11.6 4 4 7 11 11 11 3 Toxin with inhibitor cystine knot ICK or Knottin scaffold FAM163 PF15069.6 GAX18423.1 - 0.011 16.3 0.1 0.017 15.6 0.1 1.5 1 0 0 1 1 1 0 FAM163 family Organ_specific PF10950.8 GAX18423.1 - 0.34 11.6 2.0 0.74 10.5 2.0 1.6 1 1 0 1 1 1 0 Organ specific protein Ribonuclease_3 PF00636.26 GAX18424.1 - 1.5e-36 125.2 0.0 8.8e-19 68.1 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAX18424.1 - 1.9e-20 73.3 0.0 2.9e-10 40.4 0.0 3.4 3 1 0 3 3 3 2 Ribonuclease-III-like ResIII PF04851.15 GAX18424.1 - 2.3e-14 53.8 0.1 7.4e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX18424.1 - 4.3e-14 52.8 0.5 2.4e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX18424.1 - 1e-13 51.4 0.0 2.2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 GAX18424.1 - 7.5e-06 26.0 0.1 3.1e-05 24.0 0.1 2.2 1 0 0 1 1 1 1 Dicer dimerisation domain AAA_19 PF13245.6 GAX18424.1 - 0.00024 21.4 0.0 0.0007 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX18424.1 - 0.0046 17.2 0.1 0.034 14.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAX18424.1 - 0.0081 15.9 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 GAX18424.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Spore_II_R PF09551.10 GAX18424.1 - 0.082 13.4 0.1 0.34 11.4 0.0 2.1 2 0 0 2 2 1 0 Stage II sporulation protein R (spore_II_R) Piwi PF02171.17 GAX18425.1 - 1.8e-35 122.7 0.0 3.5e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Piwi domain zf-C2H2_2 PF12756.7 GAX18425.1 - 0.0071 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 GAX18426.1 - 0.0027 17.6 4.4 0.0075 16.1 4.4 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) IL3 PF02059.15 GAX18426.1 - 0.0098 15.9 0.1 0.076 13.1 0.0 2.0 2 0 0 2 2 2 1 Interleukin-3 MSP PF01716.18 GAX18429.1 - 0.0096 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Ank_2 PF12796.7 GAX18430.1 - 1.1e-11 45.2 0.1 0.02 15.5 0.0 4.3 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAX18430.1 - 3.4e-07 30.4 0.1 3.6 8.2 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 GAX18430.1 - 8e-06 26.3 0.1 0.29 11.8 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX18430.1 - 5.3e-05 23.4 0.3 3 8.3 0.0 5.9 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX18430.1 - 0.00039 20.6 0.0 14 6.6 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat PET PF06297.14 GAX18430.1 - 0.11 12.8 0.1 0.42 10.9 0.1 2.0 1 0 0 1 1 1 0 PET Domain Ank_2 PF12796.7 GAX18431.1 - 1.6e-07 31.8 0.1 1 10.0 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX18431.1 - 6.3e-06 26.6 0.0 11 6.8 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX18431.1 - 1.3e-05 25.5 1.7 0.76 10.3 0.0 5.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 GAX18431.1 - 7.6e-05 22.9 1.1 0.2 12.0 0.0 5.5 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX18431.1 - 0.00018 21.7 1.0 30 5.6 0.0 6.5 8 0 0 8 8 8 1 Ankyrin repeat SHQ1 PF04925.15 GAX18432.1 - 7.3e-39 133.1 3.3 1.2e-38 132.4 3.3 1.3 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.16 GAX18432.1 - 0.061 14.4 0.0 0.15 13.1 0.0 1.8 1 0 0 1 1 1 0 CS domain CCDC106 PF15794.5 GAX18432.1 - 0.066 12.9 0.8 0.14 11.9 0.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Chloroa_b-bind PF00504.21 GAX18433.1 - 1.2e-38 133.2 0.0 1.9e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein 7tm_3 PF00003.22 GAX18434.1 - 1.7e-37 129.4 12.9 2e-37 129.2 12.2 1.4 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX18434.1 - 3.5e-19 69.4 0.0 6.1e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 GAX18434.1 - 8.9e-06 25.3 0.5 0.002 17.6 0.0 2.9 2 1 0 2 2 2 2 Periplasmic binding proteins and sugar binding domain of LacI family ATG16 PF08614.11 GAX18435.1 - 0.00017 21.9 53.9 0.044 14.0 36.8 3.5 2 1 1 3 3 3 3 Autophagy protein 16 (ATG16) DUF5069 PF16798.5 GAX18435.1 - 0.48 10.6 5.2 1.9 8.7 5.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) Baculo_PEP_C PF04513.12 GAX18435.1 - 4.4 7.3 16.9 9.4 6.3 10.0 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 GAX18435.1 - 7 5.9 55.2 0.33 10.3 26.9 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 GAX18436.1 - 0.67 9.3 101.6 0.51 9.7 4.1 7.4 2 1 4 6 6 6 0 Tropomyosin RT_RNaseH PF17917.1 GAX18436.1 - 2.9 8.2 8.0 0.96 9.8 0.1 4.0 4 2 0 4 4 4 0 RNase H-like domain found in reverse transcriptase mCpol PF18182.1 GAX18436.1 - 4.7 7.6 19.1 12 6.2 0.7 5.4 5 0 0 5 5 5 0 minimal CRISPR polymerase domain HSBP1 PF06825.12 GAX18437.1 - 5.4e-15 55.0 8.0 6.4e-15 54.7 8.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 GAX18437.1 - 0.013 15.8 0.5 0.019 15.3 0.5 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 GAX18437.1 - 0.068 12.7 0.2 0.079 12.5 0.2 1.1 1 0 0 1 1 1 0 fzo-like conserved region IL11 PF07400.11 GAX18437.1 - 0.089 12.4 0.4 0.22 11.1 0.2 1.6 1 1 1 2 2 2 0 Interleukin 11 Osmo_CC PF08946.10 GAX18437.1 - 0.24 11.7 0.9 0.37 11.1 0.9 1.4 1 1 0 1 1 1 0 Osmosensory transporter coiled coil RRM_1 PF00076.22 GAX18438.1 - 5.3e-30 103.0 0.0 2.7e-13 49.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 GAX18438.1 - 0.00037 21.5 0.3 0.00037 21.5 0.3 2.4 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.6 GAX18438.1 - 0.00056 19.5 0.0 0.0066 16.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAP1 PF07218.11 GAX18438.1 - 3.1 6.0 14.5 4.5 5.4 14.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.11 GAX18438.1 - 3.6 6.0 8.6 5.3 5.4 8.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 RRM_1 PF00076.22 GAX18439.1 - 8.7e-19 67.1 0.3 1.9e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APG6_N PF17675.1 GAX18439.1 - 0.0036 17.8 6.9 0.0054 17.3 6.9 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region zf-CpG_bind_C PF12269.8 GAX18439.1 - 0.046 13.5 1.0 0.054 13.3 1.0 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain YabA PF06156.13 GAX18439.1 - 0.06 14.0 4.1 0.1 13.3 4.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Nup35_RRM_2 PF14605.6 GAX18439.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RmuC PF02646.16 GAX18439.1 - 0.16 11.1 3.4 0.23 10.6 3.4 1.2 1 0 0 1 1 1 0 RmuC family ADIP PF11559.8 GAX18439.1 - 0.16 12.0 8.2 0.27 11.3 8.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 GAX18439.1 - 0.2 11.9 5.9 0.31 11.3 5.9 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF812 PF05667.11 GAX18439.1 - 0.38 9.6 7.2 0.49 9.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlxA PF14282.6 GAX18439.1 - 0.53 10.3 6.5 0.82 9.7 6.5 1.2 1 0 0 1 1 1 0 FlxA-like protein T2SSM PF04612.12 GAX18439.1 - 0.58 10.2 2.0 1.1 9.4 2.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M UPF0242 PF06785.11 GAX18439.1 - 1.1 9.3 9.0 1.6 8.8 9.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 GAX18439.1 - 1.7 9.1 5.8 3.1 8.3 5.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cwf_Cwc_15 PF04889.12 GAX18439.1 - 3.5 7.3 15.1 4.8 6.8 15.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DivIC PF04977.15 GAX18439.1 - 3.7 7.4 6.6 6 6.7 6.6 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4337 PF14235.6 GAX18439.1 - 6.9 6.8 8.0 10 6.2 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) STAC2_u1 PF16664.5 GAX18439.1 - 7.5 7.0 6.5 4.1 7.9 4.6 1.5 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 FoP_duplication PF13865.6 GAX18439.1 - 8.3 7.0 11.0 22 5.7 11.0 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 60KD_IMP PF02096.20 GAX18440.1 - 2e-43 148.2 0.1 2.7e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein COX6C PF02937.15 GAX18440.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc RseA_C PF03873.13 GAX18442.1 - 0.0091 16.2 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 Anti sigma-E protein RseA, C-terminal domain YndJ PF14158.6 GAX18442.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 YndJ-like protein AcrZ PF10766.9 GAX18442.1 - 0.33 10.5 3.9 0.66 9.6 3.9 1.4 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ GNAT_acetyltr_2 PF13718.6 GAX18443.1 - 4.9e-95 317.2 2.7 1.7e-94 315.5 0.0 2.7 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 GAX18443.1 - 8.9e-62 208.9 2.5 1.3e-61 208.3 0.0 2.4 3 0 0 3 3 3 1 Possible tRNA binding domain Helicase_RecD PF05127.14 GAX18443.1 - 3.8e-53 180.0 0.1 1e-52 178.6 0.1 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 GAX18443.1 - 9.3e-30 102.4 0.0 2.3e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 GAX18443.1 - 0.061 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX18443.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 GAX18444.1 - 9.8e-19 67.7 0.0 3.4e-12 46.8 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX18444.1 - 1.5e-18 64.9 1.3 0.00038 20.7 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 GAX18444.1 - 2.5e-14 53.0 0.9 0.004 17.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 GAX18444.1 - 4e-13 49.6 0.5 0.00038 20.9 0.0 4.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX18444.1 - 3.2e-11 43.3 2.7 0.0027 18.0 0.2 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Proteasome PF00227.26 GAX18445.1 - 3.5e-06 26.6 0.0 0.00018 21.0 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit DSBA PF01323.20 GAX18446.1 - 2.8e-05 24.0 0.0 9.1e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 GAX18446.1 - 0.03 14.5 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin RCC1 PF00415.18 GAX18447.1 - 8.6e-35 119.1 30.6 1.6e-10 41.5 0.1 8.4 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX18447.1 - 2.8e-26 90.7 33.7 1.7e-09 37.2 0.6 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat zf-met PF12874.7 GAX18447.1 - 5.5e-06 26.6 1.1 5.5e-06 26.6 1.1 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Ank_2 PF12796.7 GAX18447.1 - 6.7e-05 23.4 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2_jaz PF12171.8 GAX18447.1 - 0.00056 20.1 0.6 0.0016 18.7 0.6 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SRP9-21 PF05486.12 GAX18447.1 - 0.0012 19.2 2.5 0.01 16.2 0.1 2.7 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Ank_4 PF13637.6 GAX18447.1 - 0.0094 16.5 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NnrU PF07298.11 GAX18448.1 - 3.4e-16 59.4 0.4 5.3e-13 49.0 0.3 2.9 2 1 0 2 2 2 2 NnrU protein PHBC_N PF12551.8 GAX18448.1 - 0.036 13.8 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal Peptidase_M3 PF01432.20 GAX18449.1 - 3.5e-23 82.6 0.0 3.4e-22 79.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 GAX18449.1 - 3.1e-07 29.4 0.7 4.2e-07 29.0 0.7 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme RPN7 PF10602.9 GAX18449.1 - 0.006 16.3 0.1 0.018 14.7 0.0 1.8 1 1 0 1 1 1 1 26S proteasome subunit RPN7 Ubie_methyltran PF01209.18 GAX18450.1 - 3.3e-30 105.1 0.0 4.2e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAX18450.1 - 4.7e-14 52.9 0.1 8.1e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX18450.1 - 1.4e-13 51.3 0.0 2.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX18450.1 - 3.8e-12 46.2 0.0 5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX18450.1 - 2.1e-11 43.9 0.0 2.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX18450.1 - 4.5e-09 37.0 0.1 6.8e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX18450.1 - 0.06 12.9 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RisS_PPD PF16524.5 GAX18451.1 - 0.093 13.0 3.2 0.19 12.0 0.7 2.1 1 1 1 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS ThiD2 PF17792.1 GAX18451.1 - 0.13 12.8 5.5 0.22 12.0 5.5 1.4 1 0 0 1 1 1 0 ThiD2 family DUF3612 PF12268.8 GAX18451.1 - 0.38 10.8 2.6 0.6 10.2 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) MnmE_helical PF12631.7 GAX18451.1 - 2.7 8.1 8.5 9.3 6.4 8.5 1.9 1 1 0 1 1 1 0 MnmE helical domain TMF_TATA_bd PF12325.8 GAX18451.1 - 4 7.7 18.1 4.9 7.4 1.6 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding LEA_4 PF02987.16 GAX18453.1 - 4.9e-06 26.5 88.4 0.0041 17.2 5.6 11.7 6 2 8 14 14 14 7 Late embryogenesis abundant protein YtxH PF12732.7 GAX18453.1 - 1.3e-05 25.6 64.7 0.2 12.2 8.7 8.1 2 2 2 4 4 4 2 YtxH-like protein DUF883 PF05957.13 GAX18453.1 - 0.00034 21.1 39.2 0.27 11.8 1.0 6.5 3 1 3 6 6 6 4 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 GAX18453.1 - 0.02 14.8 39.1 1 9.2 0.6 3.3 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain ApoO PF09769.9 GAX18453.1 - 8 6.4 23.8 19 5.2 2.6 5.3 3 2 2 5 5 5 0 Apolipoprotein O CBS PF00571.28 GAX18454.1 - 1.4e-18 67.1 0.6 4.4e-08 33.5 0.2 2.8 2 0 0 2 2 2 2 CBS domain DHH PF01368.20 GAX18454.1 - 1.5e-12 47.7 0.4 1.2e-11 44.7 0.0 2.4 2 1 0 2 2 2 1 DHH family EF-hand_7 PF13499.6 GAX18454.1 - 2.4e-11 43.9 0.7 1.4e-10 41.4 0.3 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX18454.1 - 3.7e-09 35.5 1.0 5.4e-05 22.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAX18454.1 - 3e-08 33.4 0.0 1.2e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX18454.1 - 1.3e-07 30.9 0.6 0.0056 16.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX18454.1 - 1.4e-05 24.3 2.1 0.0094 15.4 0.1 2.5 2 0 0 2 2 2 2 EF hand DHHA1 PF02272.19 GAX18454.1 - 0.00047 20.6 1.5 0.00091 19.7 0.0 2.3 3 0 0 3 3 3 1 DHHA1 domain SUIM_assoc PF16619.5 GAX18454.1 - 1 9.4 6.1 12 6.1 0.5 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ATP-synt_C PF00137.21 GAX18455.1 - 9.7e-32 109.1 23.7 6.8e-18 64.8 4.1 2.4 2 1 0 2 2 2 2 ATP synthase subunit C DUF2207 PF09972.9 GAX18455.1 - 0.00015 20.6 0.2 0.00026 19.9 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) ABC1 PF03109.16 GAX18456.1 - 6.5e-27 94.1 0.0 1.3e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX18456.1 - 0.00063 19.7 0.5 0.0025 17.8 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX18456.1 - 0.0014 18.1 0.0 0.16 11.3 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Histone_H2A_C PF16211.5 GAX18457.1 - 8.7e-17 60.6 1.1 2.7e-16 59.0 1.1 1.9 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAX18457.1 - 6.4e-12 46.0 8.3 6.4e-12 46.0 8.3 5.7 2 2 3 5 5 5 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX18457.1 - 0.00092 19.4 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RVT_2 PF07727.14 GAX18459.1 - 3.7e-36 125.0 0.0 7.6e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC1 PF03109.16 GAX18461.1 - 1.7e-24 86.3 0.0 3e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX18461.1 - 1.6e-05 24.9 0.0 5e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX18461.1 - 0.0011 18.4 0.6 0.26 10.6 0.3 3.0 2 1 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 GAX18461.1 - 0.11 12.1 1.8 0.34 10.5 1.5 1.9 1 1 0 2 2 2 0 RIO1 family EzrA PF06160.12 GAX18461.1 - 0.11 10.7 0.4 0.16 10.1 0.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-RING_2 PF13639.6 GAX18462.1 - 5.7e-12 45.8 5.5 5.7e-12 45.8 5.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GAX18462.1 - 8e-08 31.9 0.6 2e-07 30.6 0.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX18462.1 - 9.5e-08 31.8 5.3 2.6e-07 30.3 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX18462.1 - 2.5e-07 30.9 10.7 1.9e-06 28.1 10.7 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX18462.1 - 2.9e-06 27.0 4.8 8.5e-06 25.5 4.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX18462.1 - 0.0057 16.8 8.9 0.031 14.4 8.9 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAX18462.1 - 0.008 16.0 8.6 0.029 14.2 8.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX18462.1 - 0.013 15.5 8.8 0.013 15.5 8.8 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAX18462.1 - 0.013 15.1 8.1 0.034 13.8 8.1 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GAX18462.1 - 0.03 14.3 7.6 0.03 14.3 7.6 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAX18462.1 - 0.033 14.2 3.2 0.11 12.6 3.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 GAX18462.1 - 0.34 11.3 7.3 1.2 9.6 7.3 1.9 1 0 0 1 1 1 0 RING-like domain zf-RING_2 PF13639.6 GAX18463.1 - 5.2e-13 49.1 7.4 8e-13 48.5 7.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX18463.1 - 1e-09 38.0 0.8 1.7e-09 37.2 0.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX18463.1 - 1.2e-09 37.9 6.4 2.1e-09 37.1 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX18463.1 - 1.4e-07 31.4 1.4 1.4e-07 31.4 1.4 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAX18463.1 - 1.4e-06 28.5 12.5 3e-05 24.2 12.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX18463.1 - 6.7e-06 26.0 6.9 1e-05 25.4 6.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAX18463.1 - 1e-05 25.3 5.5 1.8e-05 24.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX18463.1 - 1.8e-05 24.5 5.5 3.4e-05 23.6 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX18463.1 - 9e-05 22.3 8.0 0.00066 19.5 8.4 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 GAX18463.1 - 0.0029 17.8 8.0 0.042 14.0 8.0 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX18463.1 - 0.02 14.5 6.4 0.02 14.5 5.2 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAX18463.1 - 0.079 13.0 5.7 0.33 11.0 5.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 GAX18463.1 - 0.32 11.2 7.6 0.96 9.7 7.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 GAX18463.1 - 0.38 11.1 7.3 0.67 10.3 7.3 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 GAX18463.1 - 1.5 8.8 8.7 1.7 8.6 6.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 GAX18463.1 - 1.5 9.0 7.7 7.1 6.8 7.7 2.0 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 GAX18463.1 - 2.8 8.0 8.0 35 4.6 8.0 2.3 1 1 0 1 1 1 0 Zinc-finger Ank_4 PF13637.6 GAX18464.1 - 3.7e-09 36.9 1.1 0.0063 17.1 0.2 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX18464.1 - 4.2e-07 30.5 0.4 0.19 12.4 0.0 3.2 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX18464.1 - 1.1e-05 25.4 0.4 0.16 12.6 0.0 5.0 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 GAX18464.1 - 0.0063 16.9 3.5 18 6.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat KR PF08659.10 GAX18465.1 - 9.8e-07 28.9 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX18465.1 - 6.4e-06 25.5 0.0 0.00011 21.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAX18465.1 - 0.00039 19.9 0.1 0.00057 19.4 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX18465.1 - 0.00054 19.5 0.1 0.00079 18.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAX18465.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 GAX18465.1 - 0.24 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ank_2 PF12796.7 GAX18466.1 - 1.1e-13 51.5 1.4 0.00065 20.2 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX18466.1 - 7.4e-12 45.6 2.9 0.0016 19.0 0.0 6.0 4 3 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX18466.1 - 8.9e-11 41.0 0.6 0.22 12.2 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAX18466.1 - 2.3e-09 37.3 0.3 3.2e-05 24.1 0.0 4.4 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX18466.1 - 0.0003 21.1 2.1 1.3 9.6 0.0 5.0 6 0 0 6 6 6 1 Ankyrin repeat Formyl_trans_N PF00551.19 GAX18467.1 - 1.1e-36 126.3 0.0 1.5e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 GAX18467.1 - 1.9e-13 50.5 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain SLATT_1 PF18181.1 GAX18468.1 - 0.076 12.9 2.2 0.32 10.9 0.1 2.5 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DAO PF01266.24 GAX18469.1 - 1.7e-22 80.5 0.0 2.1e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase zf-CCCH_3 PF15663.5 GAX18470.1 - 0.0002 21.6 5.1 0.00083 19.5 5.1 2.1 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 GAX18470.1 - 0.002 18.0 11.8 1.2 9.2 0.8 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GAX18470.1 - 0.12 12.9 9.4 0.76 10.3 2.5 3.1 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger PilX_N PF14341.6 GAX18470.1 - 0.21 11.6 0.1 0.45 10.5 0.1 1.5 1 0 0 1 1 1 0 PilX N-terminal zf_CCCH_4 PF18345.1 GAX18470.1 - 0.39 10.8 11.8 5.2 7.3 4.2 3.7 3 1 0 3 3 3 0 Zinc finger domain zf-C3H1 PF10650.9 GAX18470.1 - 0.39 10.5 6.7 6.2 6.6 0.5 2.6 2 0 0 2 2 2 0 Putative zinc-finger domain DUF3835 PF12927.7 GAX18470.1 - 0.8 10.6 6.0 2.2 9.2 0.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) Ank_2 PF12796.7 GAX18471.1 - 3e-13 50.2 0.0 3.7e-07 30.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX18471.1 - 2.4e-10 40.7 0.1 0.0014 19.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX18471.1 - 7e-09 35.2 0.1 0.00041 20.6 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 GAX18471.1 - 2.8e-07 30.7 0.1 0.0014 19.0 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX18471.1 - 0.0004 20.6 0.3 0.042 14.2 0.1 3.1 1 1 2 3 3 3 1 Ankyrin repeats (many copies) F-box PF00646.33 GAX18471.1 - 0.00041 20.1 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF2780 PF11075.8 GAX18471.1 - 0.0041 17.3 1.2 0.015 15.5 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function VcgC/VcgE (DUF2780) SecY PF00344.20 GAX18472.1 - 3.4e-71 240.0 13.2 4.5e-71 239.6 13.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GAX18472.1 - 1.1e-18 66.7 0.1 1.1e-18 66.7 0.1 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p ApbA_C PF08546.11 GAX18473.1 - 7.3e-32 110.2 0.1 1.6e-31 109.1 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAX18473.1 - 1.7e-23 83.0 0.0 2.3e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 GAX18473.1 - 0.03 13.8 0.1 0.36 10.3 0.0 2.3 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus WD40 PF00400.32 GAX18475.1 - 1.4e-12 47.9 5.3 2.1e-05 25.2 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX18475.1 - 7.8e-07 29.3 0.1 0.009 16.3 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX18475.1 - 0.018 13.7 0.2 0.036 12.7 0.2 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 UPF0113_N PF17833.1 GAX18476.1 - 5.2e-31 107.0 0.3 7.7e-31 106.5 0.3 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 GAX18476.1 - 2.1e-21 76.0 0.0 3.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 GAX18476.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain PUA PF01472.20 GAX18476.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 PUA domain IF-2B PF01008.17 GAX18477.1 - 3.5e-70 236.4 0.3 5.5e-70 235.8 0.3 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family APH PF01636.23 GAX18477.1 - 1e-14 55.0 0.0 3.1e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX18477.1 - 0.0039 16.8 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase LBR_tudor PF09465.10 GAX18479.1 - 1.5e-05 24.7 15.5 0.036 13.9 3.3 3.5 3 0 0 3 3 3 3 Lamin-B receptor of TUDOR domain DUF5447 PF17525.2 GAX18479.1 - 0.083 13.4 0.1 15 6.1 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5447) CDRT4 PF15213.6 GAX18479.1 - 0.23 12.0 2.2 0.46 11.1 2.2 1.4 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Agenet PF05641.12 GAX18479.1 - 0.85 10.1 4.7 1.3 9.5 0.3 2.7 2 0 0 2 2 2 0 Agenet domain TPR_1 PF00515.28 GAX18480.1 - 1.3e-20 72.2 25.1 7.4e-05 22.4 1.9 7.0 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18480.1 - 2.9e-17 61.3 37.9 0.00021 21.1 2.5 7.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18480.1 - 3.2e-10 40.5 31.9 0.0016 19.0 9.8 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat FYVE PF01363.21 GAX18480.1 - 1.1e-07 31.9 2.3 2.6e-07 30.7 2.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger TPR_8 PF13181.6 GAX18480.1 - 4.9e-07 29.4 22.0 0.004 17.2 0.5 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18480.1 - 5.3e-07 29.2 20.4 0.029 14.0 5.5 5.1 4 1 1 5 5 5 3 TPR repeat Synaptobrevin PF00957.21 GAX18480.1 - 1.3e-05 24.9 2.6 2.3e-05 24.1 0.3 2.3 2 0 0 2 2 2 1 Synaptobrevin Ank_2 PF12796.7 GAX18480.1 - 0.00013 22.4 0.0 0.31 11.6 0.0 3.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) TPR_14 PF13428.6 GAX18480.1 - 0.0013 19.4 33.0 0.069 14.0 1.6 7.5 4 4 3 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX18480.1 - 0.0039 17.4 19.9 0.44 10.9 7.3 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat FYVE_2 PF02318.16 GAX18480.1 - 0.004 17.3 1.1 0.004 17.3 1.1 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger Ank PF00023.30 GAX18480.1 - 0.058 13.9 0.0 5.9 7.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat DUF4428 PF14471.6 GAX18480.1 - 0.12 12.3 0.3 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) TPR_17 PF13431.6 GAX18480.1 - 0.17 12.3 0.1 0.17 12.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX18480.1 - 0.26 10.8 2.3 15 5.2 0.0 3.1 3 0 0 3 3 3 0 SHNi-TPR DUF2197 PF09963.9 GAX18480.1 - 0.36 11.1 2.1 0.91 9.8 2.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) TPR_10 PF13374.6 GAX18480.1 - 1.2 9.1 24.1 2.7 8.0 0.5 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX18480.1 - 1.3 9.2 15.8 1.4 9.2 3.5 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 GAX18480.1 - 3.5 8.0 20.1 2 8.8 10.7 4.0 3 2 1 4 4 4 0 Bacterial transcriptional activator domain BLM10_mid PF16507.5 GAX18482.1 - 6.7e-48 163.6 0.0 2.1e-47 162.0 0.0 1.8 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 GAX18482.1 - 5.2e-22 77.6 0.1 2.6e-21 75.3 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Sigma70_ner PF04546.13 GAX18482.1 - 0.00043 20.2 5.3 0.0013 18.6 5.3 1.8 1 0 0 1 1 1 1 Sigma-70, non-essential region Nop14 PF04147.12 GAX18482.1 - 0.0026 16.1 5.1 0.0043 15.3 5.1 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GAX18482.1 - 0.011 15.2 5.4 0.021 14.3 5.4 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAX18482.1 - 0.016 13.6 4.4 0.027 12.8 4.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAX18482.1 - 0.086 10.9 23.5 0.19 9.8 23.5 1.6 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 GAX18482.1 - 0.48 10.0 7.6 1.7 8.2 7.6 2.0 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting HEAT PF02985.22 GAX18482.1 - 0.81 10.1 5.7 10 6.7 0.0 4.6 5 0 0 5 5 3 0 HEAT repeat RRN3 PF05327.11 GAX18482.1 - 1.2 7.6 11.9 2.4 6.6 11.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.12 GAX18482.1 - 1.7 8.3 24.3 4.4 7.0 24.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 GAX18482.1 - 2.5 8.1 11.9 6.4 6.8 11.9 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 GAX18482.1 - 2.9 7.5 5.4 9.5 5.9 5.4 1.9 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 GAX18482.1 - 3.4 6.7 30.7 5.8 5.9 30.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HEAT_EZ PF13513.6 GAX18482.1 - 3.8 8.1 6.7 98 3.6 0.0 5.7 7 0 0 7 7 5 0 HEAT-like repeat YL1 PF05764.13 GAX18482.1 - 6.6 6.8 15.6 17 5.5 15.6 1.6 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 GAX18482.1 - 8 5.7 25.0 16 4.7 25.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF647 PF04884.14 GAX18483.1 - 9.5e-60 202.2 1.9 1.4e-59 201.7 1.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis CAP_N PF01213.19 GAX18483.1 - 0.085 12.3 0.3 0.14 11.6 0.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2701 PF10857.8 GAX18484.1 - 1.1 9.3 5.8 0.97 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) DUF805 PF05656.14 GAX18485.1 - 0.0078 16.6 0.3 0.0098 16.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DUF4474 PF14751.6 GAX18486.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) HMA PF00403.26 GAX18488.1 - 7.6e-15 55.1 0.2 8.5e-15 55.0 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 GAX18488.1 - 0.019 15.3 0.1 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain GFRP PF06399.13 GAX18488.1 - 0.092 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) MFS_1 PF07690.16 GAX18489.1 - 1.1e-19 70.6 23.7 2.9e-19 69.2 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX18489.1 - 9.4e-18 64.3 24.8 2.7e-13 49.6 6.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 GAX18489.1 - 5e-06 26.1 6.1 5e-06 26.1 6.1 2.5 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB ANAPC4_WD40 PF12894.7 GAX18490.1 - 3.6e-08 33.6 1.2 0.57 10.5 0.0 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX18490.1 - 8.5e-05 23.3 4.0 0.3 12.0 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat TFIIIC_delta PF12657.7 GAX18490.1 - 0.00035 20.6 0.1 0.0012 18.8 0.1 1.9 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Pribosyltran PF00156.27 GAX18490.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain WD40 PF00400.32 GAX18492.1 - 3.4e-15 56.2 11.2 0.0011 19.8 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX18492.1 - 3.9e-15 55.9 3.2 0.013 15.8 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 GAX18492.1 - 0.00021 20.7 0.1 0.044 13.1 0.0 2.4 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.7 GAX18492.1 - 0.00049 20.1 0.1 0.0016 18.4 0.1 2.1 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Herpes_glycop_D PF01537.17 GAX18492.1 - 0.054 13.7 0.3 0.47 10.6 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus glycoprotein D/GG/GX domain Evr1_Alr PF04777.13 GAX18493.1 - 1.9e-28 98.8 4.0 1.9e-28 98.8 4.0 1.6 2 0 0 2 2 2 1 Erv1 / Alr family FSH1 PF03959.13 GAX18495.1 - 1.1e-14 54.6 0.0 7e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 GAX18495.1 - 0.018 14.7 0.0 0.26 10.9 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX18495.1 - 0.025 14.1 0.0 0.084 12.3 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAX18495.1 - 0.048 14.2 0.0 0.13 12.8 0.0 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAX18495.1 - 0.083 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase ANAPC4_WD40 PF12894.7 GAX18496.1 - 9.2e-17 61.1 4.5 0.0017 18.6 0.1 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX18496.1 - 1.3e-14 54.4 11.8 0.002 18.9 0.2 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 GAX18496.1 - 6.1e-05 22.5 0.0 0.003 16.9 0.0 2.3 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIIC_delta PF12657.7 GAX18496.1 - 0.00012 22.1 0.0 0.00041 20.3 0.0 1.9 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Nbas_N PF15492.6 GAX18496.1 - 0.0041 16.5 0.3 1 8.7 0.0 2.5 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Sec1 PF00995.23 GAX18499.1 - 5.5e-111 372.6 0.0 6.5e-111 372.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family O-FucT PF10250.9 GAX18500.1 - 3.2e-44 152.0 0.0 4.1e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 GAX18501.1 - 1.7e-44 152.9 0.0 2.5e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase YtpI PF14007.6 GAX18501.1 - 0.13 12.4 0.0 5.3 7.2 0.0 2.9 3 0 0 3 3 3 0 YtpI-like protein Baculo_PEP_C PF04513.12 GAX18502.1 - 0.35 10.9 4.6 0.43 10.6 0.3 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.29 GAX18503.1 - 6e-97 321.2 0.0 3.1e-47 160.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX18503.1 - 5.2e-28 96.6 7.2 5.1e-15 55.0 0.9 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 GAX18503.1 - 1.3e-21 76.6 1.0 3.5e-21 75.2 1.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 GAX18503.1 - 2.1e-14 53.5 0.0 6.5e-06 26.0 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 GAX18503.1 - 2.8e-14 52.6 0.0 6e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 GAX18503.1 - 2.9e-12 47.0 0.0 7.4e-06 26.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAX18503.1 - 6.6e-12 46.1 2.2 0.00026 21.4 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 GAX18503.1 - 1.7e-11 44.5 0.0 2e-05 24.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 GAX18503.1 - 1.9e-10 40.9 0.1 2.7e-05 24.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX18503.1 - 2.3e-09 37.6 0.2 0.031 14.5 0.1 4.6 3 2 1 4 4 4 2 AAA domain TIP49 PF06068.13 GAX18503.1 - 5.2e-08 32.5 0.0 0.00064 19.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 GAX18503.1 - 1.4e-07 31.6 0.0 0.0066 16.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX18503.1 - 5.2e-07 30.3 0.0 0.045 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAX18503.1 - 7.1e-07 29.6 0.0 0.015 15.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 GAX18503.1 - 9.9e-07 28.3 0.3 0.059 12.8 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 GAX18503.1 - 2.8e-06 27.2 0.6 0.00026 20.9 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 GAX18503.1 - 7.7e-06 25.6 0.2 1.7 8.1 0.0 3.6 2 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 GAX18503.1 - 1e-05 25.4 0.1 0.24 11.1 0.0 3.0 2 1 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 GAX18503.1 - 1.3e-05 24.6 0.2 1.9 7.8 0.0 3.4 3 0 0 3 3 3 1 KaiC AAA_7 PF12775.7 GAX18503.1 - 1.5e-05 24.6 0.0 0.089 12.3 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 GAX18503.1 - 1.7e-05 25.3 1.3 0.094 13.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 GAX18503.1 - 2.4e-05 24.4 0.0 0.18 11.7 0.0 3.0 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea ABC_tran PF00005.27 GAX18503.1 - 2.6e-05 24.7 0.0 0.14 12.6 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 GAX18503.1 - 7.6e-05 23.0 0.1 0.51 10.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 GAX18503.1 - 8.3e-05 22.3 0.0 0.57 9.9 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 GAX18503.1 - 8.6e-05 22.4 0.0 0.014 15.2 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 GAX18503.1 - 0.00012 22.1 0.0 0.54 10.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAX18503.1 - 0.00013 21.8 0.0 0.18 11.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 GAX18503.1 - 0.00017 21.5 0.0 2.7 7.9 0.0 3.7 3 1 1 4 4 3 1 NACHT domain Cytidylate_kin2 PF13189.6 GAX18503.1 - 0.00019 21.6 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase-like family Bac_DnaA PF00308.18 GAX18503.1 - 0.0002 21.3 0.0 0.3 10.9 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 GAX18503.1 - 0.00023 20.4 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 GAX18503.1 - 0.0003 20.1 0.1 0.99 8.5 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activ_2 PF14532.6 GAX18503.1 - 0.00038 20.6 0.0 0.48 10.5 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAX18503.1 - 0.00039 19.8 0.0 0.68 9.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 GAX18503.1 - 0.00045 19.5 0.0 0.13 11.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 GAX18503.1 - 0.00055 20.0 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 GAX18503.1 - 0.0012 18.7 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAX18503.1 - 0.0014 18.6 0.0 0.56 10.1 0.0 3.0 3 1 0 3 3 2 1 Rad17 P-loop domain PhoH PF02562.16 GAX18503.1 - 0.0033 16.9 0.1 3.2 7.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein NTPase_1 PF03266.15 GAX18503.1 - 0.0041 17.0 0.6 4.5 7.1 0.0 3.9 3 1 1 4 4 4 0 NTPase DUF2075 PF09848.9 GAX18503.1 - 0.0053 16.0 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UFD1 PF03152.14 GAX18503.1 - 0.0072 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_19 PF13245.6 GAX18503.1 - 0.0078 16.6 0.3 8.6 6.7 0.1 3.2 2 1 0 3 3 2 0 AAA domain AAA_30 PF13604.6 GAX18503.1 - 0.0094 15.7 0.1 7.1 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAX18503.1 - 0.011 15.5 0.2 5.1 6.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain SKI PF01202.22 GAX18503.1 - 0.03 14.4 0.0 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase Zot PF05707.12 GAX18503.1 - 0.032 13.9 0.0 1.1 8.9 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 GAX18503.1 - 0.04 13.6 0.0 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 GAX18503.1 - 0.049 12.9 0.1 2.7 7.1 0.0 3.2 2 2 1 4 4 4 0 KAP family P-loop domain TniB PF05621.11 GAX18503.1 - 0.077 12.4 0.0 17 4.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein AAA_29 PF13555.6 GAX18503.1 - 0.088 12.6 0.0 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Choline_transpo PF04515.12 GAX18504.1 - 2.5e-57 194.6 21.7 2.5e-57 194.6 21.7 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4257 PF14074.6 GAX18504.1 - 0.0087 16.3 0.7 0.028 14.6 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4257) NAD_Gly3P_dh_C PF07479.14 GAX18506.1 - 9.2e-46 155.7 0.0 1.8e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 GAX18506.1 - 5.3e-44 150.0 0.0 1e-43 149.0 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_transf_5 PF08323.11 GAX18506.1 - 0.048 13.3 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 Starch synthase catalytic domain GDP_Man_Dehyd PF16363.5 GAX18507.1 - 2.7e-59 201.2 0.0 3.1e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX18507.1 - 5.3e-52 176.7 0.0 6.4e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX18507.1 - 3.2e-17 62.5 0.0 6.6e-17 61.4 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAX18507.1 - 5.5e-15 55.3 0.0 3.2e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAX18507.1 - 9e-11 42.0 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GAX18507.1 - 1.2e-08 34.5 0.0 5.6e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 GAX18507.1 - 4.7e-06 25.9 0.0 8.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAX18507.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 GAX18507.1 - 1.5e-05 24.6 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX18507.1 - 0.0071 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 GAX18507.1 - 0.02 14.5 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Fcf1 PF04900.12 GAX18508.1 - 2e-08 34.5 0.0 1.2e-07 32.1 0.0 2.2 1 1 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 GAX18508.1 - 0.0011 19.2 0.0 0.0034 17.7 0.0 1.9 1 1 1 2 2 2 1 PIN like domain PIN_3 PF13470.6 GAX18508.1 - 0.018 15.8 1.5 0.033 14.9 1.5 1.8 1 1 0 1 1 1 0 PIN domain DNA_primase_lrg PF04104.14 GAX18509.1 - 2.5e-65 220.5 0.1 4.6e-65 219.7 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF3731 PF12531.8 GAX18509.1 - 0.013 15.4 0.9 0.061 13.1 0.3 2.2 1 1 1 3 3 3 0 DNA-K related protein Ribosomal_L2_C PF03947.18 GAX18510.1 - 1.4e-42 144.9 1.5 1.8e-42 144.5 1.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain F-box PF00646.33 GAX18511.1 - 8.5e-06 25.5 0.4 2.3e-05 24.2 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAX18511.1 - 0.00018 21.3 0.1 0.00046 20.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like Trm112p PF03966.16 GAX18512.1 - 1e-10 42.0 0.0 1.3e-10 41.7 0.0 1.3 1 1 0 1 1 1 1 Trm112p-like protein GTP1_OBG PF01018.22 GAX18513.1 - 2.8e-47 160.2 6.6 1.2e-25 89.9 0.3 2.3 1 1 1 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 GAX18513.1 - 4.8e-24 84.6 0.0 2.5e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF1967 PF09269.11 GAX18513.1 - 9.6e-18 63.9 0.0 6e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) FeoB_N PF02421.18 GAX18513.1 - 2.4e-10 40.1 0.0 4.9e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 GAX18513.1 - 0.0015 18.0 0.1 0.16 11.4 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX18513.1 - 0.027 14.0 0.0 0.74 9.3 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 GAX18513.1 - 0.032 14.0 0.0 0.077 12.7 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 GAX18513.1 - 0.044 13.6 0.1 2.3 7.9 0.1 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 GAX18513.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 GAX18513.1 - 0.096 12.6 0.1 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 GAX18513.1 - 0.11 11.4 0.0 7.3 5.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Methyltr_RsmB-F PF01189.17 GAX18514.1 - 1.2e-21 77.3 0.1 1.6e-20 73.6 0.1 2.1 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 GAX18514.1 - 5e-14 52.7 0.2 1e-13 51.6 0.2 1.5 1 0 0 1 1 1 1 NusB family DNA_methylase PF00145.17 GAX18514.1 - 9e-05 22.0 0.0 0.0002 20.8 0.0 1.5 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.15 GAX18514.1 - 0.00016 21.4 0.2 0.068 12.8 0.0 2.5 3 0 0 3 3 3 2 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 GAX18514.1 - 0.00026 21.6 0.0 0.0011 19.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 GAX18514.1 - 0.0023 18.0 0.1 0.0047 17.1 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Copine PF07002.16 GAX18515.1 - 2.1e-27 96.0 0.1 4.3e-27 95.0 0.1 1.5 1 1 0 1 1 1 1 Copine C2 PF00168.30 GAX18515.1 - 4.8e-16 58.9 0.0 2.5e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain TRAM_LAG1_CLN8 PF03798.16 GAX18516.1 - 6.3e-10 39.1 16.8 8.3e-10 38.7 16.8 1.2 1 0 0 1 1 1 1 TLC domain PseudoU_synth_2 PF00849.22 GAX18517.1 - 4.4e-21 75.6 0.1 1.9e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF1654 PF07867.11 GAX18517.1 - 0.00016 21.3 0.3 0.0014 18.4 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1654) VWA_2 PF13519.6 GAX18518.1 - 0.03 14.9 0.0 0.063 13.9 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain UFD1 PF03152.14 GAX18519.1 - 8.3e-75 250.0 0.0 1.1e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 MDD_C PF18376.1 GAX18520.1 - 8.4e-71 237.6 0.0 1.2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 GAX18520.1 - 1.9e-08 34.4 2.9 4.5e-08 33.2 2.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain IGPD PF00475.18 GAX18521.1 - 0.1 12.9 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase Nitroreductase PF00881.24 GAX18523.1 - 8e-26 91.1 0.1 2e-24 86.6 0.1 2.2 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 GAX18523.1 - 1.3e-07 31.4 0.0 0.0058 16.2 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase ABC_membrane PF00664.23 GAX18524.1 - 1.3e-48 166.1 9.8 1.3e-48 166.1 9.8 1.5 2 0 0 2 2 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAX18524.1 - 3.8e-34 118.1 0.0 6.9e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAX18524.1 - 7.9e-05 22.2 0.0 0.0028 17.1 0.0 2.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAX18524.1 - 0.00011 22.1 0.0 0.00034 20.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GAX18524.1 - 0.00025 21.4 0.3 0.0034 17.7 0.3 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX18524.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 GAX18524.1 - 0.0027 18.1 0.1 0.013 15.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 GAX18524.1 - 0.014 14.5 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 GAX18524.1 - 0.016 15.6 0.0 0.093 13.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAX18524.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX18524.1 - 0.078 13.2 0.6 0.25 11.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX18524.1 - 0.11 13.1 0.1 0.4 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.6 GAX18524.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 GAX18524.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 GAX18524.1 - 0.18 12.0 1.0 1.9 8.8 1.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PIEZO PF15917.5 GAX18524.1 - 1.1 8.7 2.6 2 7.9 2.6 1.3 1 0 0 1 1 1 0 Piezo CAP_GLY PF01302.25 GAX18525.1 - 2.9e-16 59.2 0.1 5.2e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain KASH_CCD PF14662.6 GAX18525.1 - 0.0042 16.9 27.0 0.0042 16.9 27.0 5.2 3 1 2 5 5 5 1 Coiled-coil region of CCDC155 or KASH TUDOR PF00567.24 GAX18525.1 - 0.11 12.5 2.9 2.9 7.9 0.0 4.1 2 1 1 3 3 3 0 Tudor domain Nop25 PF09805.9 GAX18526.1 - 2.4e-11 44.3 21.6 1.3e-10 41.8 21.5 2.2 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) DUF1677 PF07911.13 GAX18526.1 - 0.038 14.4 0.4 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) Tho2 PF11262.8 GAX18526.1 - 6 6.0 9.3 0.29 10.3 3.7 1.6 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Radical_SAM PF04055.21 GAX18527.1 - 6.4e-08 33.2 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily VDE PF07137.11 GAX18528.1 - 1.4e-24 87.0 0.0 2.3e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 VDE lipocalin domain Pyr_redox_2 PF07992.14 GAX18529.1 - 1.1e-32 113.4 0.0 1.5e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX18529.1 - 1.9e-08 34.7 0.0 5.5e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX18529.1 - 4.1e-05 22.8 0.6 0.00051 19.2 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 GAX18529.1 - 0.00094 18.4 0.1 0.075 12.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAX18529.1 - 0.0025 17.1 0.0 0.024 13.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX18529.1 - 0.018 14.3 2.9 0.096 11.9 0.0 3.0 4 0 0 4 4 4 0 Thi4 family Lipocalin_5 PF13924.6 GAX18530.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipocalin-like domain 4HB_MCP_1 PF12729.7 GAX18530.1 - 0.29 10.7 0.0 0.49 9.9 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Lactamase_B_2 PF12706.7 GAX18531.1 - 0.00032 20.3 0.1 0.00062 19.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX18531.1 - 0.00099 19.2 4.2 0.0024 17.9 3.0 1.9 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 GAX18531.1 - 0.058 12.5 0.4 0.086 11.9 0.4 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II PDEase_I PF00233.19 GAX18532.1 - 1.9e-25 90.0 0.0 4.9e-20 72.3 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 GAX18533.1 - 5.6e-26 91.7 0.1 1.4e-21 77.3 0.0 2.6 3 0 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase VWA PF00092.28 GAX18534.1 - 0.065 13.5 0.1 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF111 PF01969.17 GAX18536.1 - 2.6e-65 220.9 2.7 3.9e-65 220.4 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF111 HSP20 PF00011.21 GAX18537.1 - 4.2e-15 55.7 0.4 6.7e-15 55.1 0.4 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAX18537.1 - 0.00087 18.8 0.1 0.0017 17.9 0.1 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA R3H PF01424.22 GAX18538.1 - 1.8e-10 40.6 0.5 5.2e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 R3H domain Radical_SAM PF04055.21 GAX18539.1 - 1.3e-11 45.2 0.0 5.1e-11 43.2 0.0 2.0 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 GAX18539.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Arf PF00025.21 GAX18539.1 - 0.14 11.6 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Methyltransf_4 PF02390.17 GAX18540.1 - 3.4e-44 150.3 0.0 4.2e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 GAX18540.1 - 8.2e-06 26.4 0.0 1.9e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX18540.1 - 0.00025 21.6 0.0 0.00054 20.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX18540.1 - 0.0022 17.8 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX18540.1 - 0.0031 18.2 0.0 0.0078 16.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX18540.1 - 0.0032 17.3 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAX18540.1 - 0.0034 16.9 0.0 0.012 15.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAX18540.1 - 0.0047 16.9 0.0 0.0086 16.1 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX18540.1 - 0.13 11.6 0.0 0.31 10.3 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family SHS2_Rpb7-N PF03876.17 GAX18540.1 - 0.15 12.5 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RrnaAD PF00398.20 GAX18540.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 GAX18540.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_M32 PF02074.15 GAX18541.1 - 1.3e-167 558.5 0.6 1.5e-167 558.2 0.6 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Swi3 PF07962.12 GAX18542.1 - 8.5e-13 48.1 0.0 1.7e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 MCM PF00493.23 GAX18543.1 - 8.4e-97 322.7 0.0 1.3e-96 322.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX18543.1 - 4.6e-32 110.5 0.7 8.9e-32 109.6 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX18543.1 - 3.5e-24 85.0 1.9 8.1e-24 83.9 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 GAX18543.1 - 2.3e-07 30.9 0.9 4e-05 23.6 0.0 3.6 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX18543.1 - 1.4e-06 27.9 0.1 0.00016 21.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 GAX18543.1 - 0.00012 22.7 0.4 0.00012 22.7 0.4 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal MCM_N PF14551.6 GAX18543.1 - 0.0017 18.9 9.1 0.0038 17.8 4.8 3.1 2 1 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.11 GAX18543.1 - 0.0022 17.8 0.0 0.0066 16.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ddrB-ParB PF18763.1 GAX18543.1 - 0.0078 16.3 0.0 0.36 10.9 0.0 3.4 4 1 0 4 4 3 1 ddrB-like ParB superfamily domain AAA_lid_2 PF17863.1 GAX18543.1 - 0.0091 15.8 0.2 0.026 14.4 0.2 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 GAX18543.1 - 0.017 15.5 0.1 0.017 15.5 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain Zn-ribbon_8 PF09723.10 GAX18543.1 - 0.018 15.2 1.8 0.051 13.7 1.8 1.8 1 0 0 1 1 1 0 Zinc ribbon domain NTPase_1 PF03266.15 GAX18543.1 - 0.039 13.9 0.1 2 8.3 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF5358 PF17311.2 GAX18543.1 - 0.045 13.8 1.6 0.11 12.6 1.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5358) DZR PF12773.7 GAX18543.1 - 0.065 13.3 0.8 0.15 12.1 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 GAX18543.1 - 0.072 13.1 0.1 0.24 11.4 0.1 1.9 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AAA PF00004.29 GAX18543.1 - 0.072 13.5 1.8 0.13 12.7 0.0 2.5 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 GAX18543.1 - 0.2 11.9 1.6 0.42 10.8 0.3 2.1 2 0 0 2 2 2 0 Midasin AAA lid domain zf-ribbon_3 PF13248.6 GAX18543.1 - 3.1 7.3 6.5 9.7 5.8 0.5 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF2951 PF11166.8 GAX18543.1 - 5.4 7.3 5.9 1.3 9.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Methyltransf_16 PF10294.9 GAX18544.1 - 4.2e-11 42.9 0.0 7.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAX18544.1 - 2e-05 24.1 0.0 2.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX18544.1 - 0.00086 20.0 0.0 0.0025 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Glyco_trans_1_4 PF13692.6 GAX18544.1 - 0.0035 17.8 0.4 0.092 13.2 0.1 2.2 1 1 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX18544.1 - 0.033 13.7 0.1 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Methyltransf_12 PF08242.12 GAX18544.1 - 0.1 13.4 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAX18544.1 - 0.13 12.1 0.0 0.44 10.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 GAX18544.1 - 0.14 11.4 0.2 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain Glyco_tranf_2_4 PF13704.6 GAX18545.1 - 4.3e-09 36.8 0.5 1.6e-08 35.0 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX18545.1 - 0.00027 20.7 2.8 0.0012 18.6 2.8 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 92 MatE PF01554.18 GAX18546.1 - 2.6e-38 131.2 21.0 9.7e-20 70.8 4.5 3.5 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 GAX18546.1 - 1.3e-09 38.2 6.3 1.3e-09 38.2 6.3 4.2 5 1 0 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Topoisom_I PF01028.20 GAX18547.1 - 4.4e-90 301.0 8.5 4.4e-90 301.0 8.5 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 GAX18547.1 - 1.3e-79 266.6 0.7 1.3e-79 266.6 0.7 4.4 4 2 2 6 6 6 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 GAX18547.1 - 3.2e-35 119.9 1.0 3.2e-35 119.9 1.0 2.8 2 0 0 2 2 2 1 C-terminal topoisomerase domain Sec66 PF09802.9 GAX18547.1 - 0.0082 15.7 10.9 0.12 11.9 0.1 2.8 2 0 0 2 2 2 2 Preprotein translocase subunit Sec66 HsbA PF12296.8 GAX18547.1 - 0.019 15.4 0.3 0.019 15.4 0.3 2.6 4 0 0 4 4 4 0 Hydrophobic surface binding protein A Allexi_40kDa PF05549.11 GAX18547.1 - 0.23 10.9 4.5 0.67 9.4 4.5 1.8 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1129 PF06570.11 GAX18547.1 - 0.79 9.2 3.3 2.2 7.7 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF948 PF06103.11 GAX18547.1 - 2.6 8.4 4.5 2.5 8.4 1.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1604 PF07713.13 GAX18548.1 - 3.8e-19 68.3 3.3 3.8e-19 68.3 3.3 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) tRNA-synt_1e PF01406.19 GAX18549.1 - 1.6e-110 369.2 0.1 2.8e-110 368.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAX18549.1 - 1.7e-06 27.1 0.4 0.00083 18.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 GAX18549.1 - 0.075 11.9 1.9 0.11 11.3 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Chloroa_b-bind PF00504.21 GAX18551.1 - 8.7e-08 32.9 0.0 0.024 15.1 0.0 2.2 1 1 0 2 2 2 2 Chlorophyll A-B binding protein SelR PF01641.18 GAX18552.1 - 0.00078 19.5 0.0 0.0028 17.7 0.0 1.9 1 1 0 1 1 1 1 SelR domain HAD_2 PF13419.6 GAX18554.1 - 6.9e-19 68.6 0.0 1.2e-18 67.9 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX18554.1 - 2e-10 41.3 0.0 8.7e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX18554.1 - 3.8e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like 2OG-FeII_Oxy_2 PF13532.6 GAX18555.1 - 4.7e-30 105.2 0.0 6.6e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TAL_FSA PF00923.19 GAX18556.1 - 1.5e-88 296.9 0.1 1.7e-88 296.7 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DAP3 PF10236.9 GAX18558.1 - 7.8e-16 58.1 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 GAX18558.1 - 0.00065 20.1 0.5 0.0036 17.7 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX18558.1 - 0.0054 17.0 0.0 0.086 13.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAX18558.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAX18558.1 - 0.051 14.1 0.0 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAX18558.1 - 0.076 12.7 0.2 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 GAX18558.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 GAX18558.1 - 0.27 11.0 2.0 0.26 11.0 0.2 1.9 2 0 0 2 2 2 0 AAA domain Cpn10 PF00166.21 GAX18559.1 - 2.2e-43 146.2 6.2 3e-22 78.5 0.6 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit AAA PF00004.29 GAX18561.1 - 5.8e-41 140.0 0.0 1.7e-40 138.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX18561.1 - 2.7e-09 36.7 0.2 7.6e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 GAX18561.1 - 6.5e-06 26.4 0.0 1.5e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX18561.1 - 0.00012 22.1 0.1 0.00053 20.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX18561.1 - 0.00084 19.8 0.1 0.0062 16.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX18561.1 - 0.00091 19.5 0.1 0.0074 16.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GAX18561.1 - 0.0046 16.1 0.0 0.0084 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAX18561.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GAX18561.1 - 0.019 15.2 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX18561.1 - 0.032 14.0 0.1 0.15 11.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX18561.1 - 0.035 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX18561.1 - 0.052 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAX18561.1 - 0.067 12.6 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX18561.1 - 0.079 12.5 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAX18561.1 - 0.082 13.3 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 GAX18561.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RRM_1 PF00076.22 GAX18562.1 - 2.8e-16 59.1 0.0 4.7e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_4 PF12146.8 GAX18563.1 - 2.6e-11 43.3 0.0 2.1e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX18563.1 - 3.9e-08 33.3 0.2 4.7e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX18563.1 - 4e-05 24.3 0.0 0.0001 23.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX18563.1 - 0.0051 16.3 0.0 0.098 12.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 GAX18563.1 - 0.0098 15.0 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 GAX18563.1 - 0.049 13.5 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF818 PF05677.12 GAX18563.1 - 0.061 12.3 0.4 0.1 11.5 0.1 1.5 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) Haemadin PF09065.10 GAX18563.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.5 2 0 0 2 2 2 0 Haemadin FSH1 PF03959.13 GAX18563.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ank_2 PF12796.7 GAX18564.1 - 1.7e-10 41.3 0.0 0.0036 17.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX18564.1 - 2.5e-10 40.4 0.5 0.42 11.0 0.2 5.4 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX18564.1 - 2.6e-08 33.5 2.8 2.5 8.9 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 GAX18564.1 - 1e-06 29.2 0.5 0.25 12.0 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX18564.1 - 4.4e-06 26.9 1.9 3.3 8.3 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Choline_transpo PF04515.12 GAX18565.1 - 2.4e-52 178.2 12.6 2.4e-52 178.2 12.6 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter G0-G1_switch_2 PF15103.6 GAX18565.1 - 0.12 12.9 1.7 0.57 10.6 0.0 2.6 3 0 0 3 3 3 0 G0/G1 switch protein 2 SNase PF00565.17 GAX18566.1 - 3.3e-19 69.4 0.0 5.5e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Lipase_GDSL_2 PF13472.6 GAX18567.1 - 1.2e-15 58.4 0.0 1.9e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX18567.1 - 4.3e-11 43.2 0.0 5.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Mito_carr PF00153.27 GAX18568.1 - 3e-65 216.2 2.6 9.9e-22 76.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_11 PF08241.12 GAX18569.1 - 4.5e-19 68.9 0.0 8.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX18569.1 - 1e-16 61.4 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX18569.1 - 1.2e-11 45.2 0.0 2.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX18569.1 - 1.2e-11 44.4 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAX18569.1 - 1.5e-10 41.1 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX18569.1 - 6.3e-05 22.9 0.0 9.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAX18569.1 - 0.00086 19.2 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase TPR_12 PF13424.6 GAX18570.1 - 1e-38 131.4 12.8 1.6e-13 50.7 4.6 6.8 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18570.1 - 6e-24 82.8 10.5 0.0018 18.0 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18570.1 - 7.7e-18 63.1 12.8 0.0013 18.7 0.0 8.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18570.1 - 4.6e-17 60.7 7.5 0.035 14.3 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAX18570.1 - 3.8e-15 54.7 1.0 0.00027 20.7 0.0 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18570.1 - 1.3e-13 50.3 17.4 5.5e-05 22.9 0.2 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX18570.1 - 2e-11 43.9 0.4 2e-11 43.9 0.4 2.5 3 0 0 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 GAX18570.1 - 2.3e-11 43.5 6.1 0.02 15.7 0.1 6.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18570.1 - 8.1e-08 31.8 3.8 0.0012 18.5 0.0 5.3 6 0 0 6 6 6 1 TPR repeat TPR_16 PF13432.6 GAX18570.1 - 0.00027 21.5 7.2 0.023 15.3 2.2 5.2 5 2 1 6 6 6 2 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX18570.1 - 0.00029 20.8 4.1 2.5 8.2 0.1 4.8 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 5 TPR_9 PF13371.6 GAX18570.1 - 0.00081 19.5 1.0 1.3 9.3 0.0 4.2 3 1 2 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 GAX18570.1 - 0.0047 16.7 0.6 0.58 9.9 0.1 3.0 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_4 PF07721.14 GAX18570.1 - 0.018 15.6 4.8 0.083 13.6 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX18570.1 - 0.032 14.6 0.2 19 5.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat SPO22 PF08631.10 GAX18570.1 - 0.05 13.1 2.5 12 5.3 0.0 3.6 2 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 GAX18570.1 - 0.057 14.1 6.5 7.4 7.4 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 GAX18570.1 - 0.084 13.0 1.0 12 6.1 0.0 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 GAX18570.1 - 0.51 9.8 2.4 31 4.1 0.3 3.7 4 0 0 4 4 4 0 SHNi-TPR G-alpha PF00503.20 GAX18571.1 - 4.3e-95 318.9 0.0 5e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAX18571.1 - 4.1e-15 55.7 0.8 6.7e-12 45.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAX18571.1 - 0.00011 22.4 0.1 0.43 10.8 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAX18571.1 - 0.00021 20.7 0.2 0.046 13.1 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAX18571.1 - 0.0059 16.7 0.0 0.39 10.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX18571.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain vATP-synt_AC39 PF01992.16 GAX18572.1 - 7.2e-108 361.1 0.1 8.1e-108 360.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit HHH_8 PF14716.6 GAX18573.1 - 1.3e-11 44.6 0.3 1.3e-11 44.6 0.3 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain zf-PARP PF00645.18 GAX18573.1 - 2.2e-07 31.6 0.0 2.2e-07 31.6 0.0 3.2 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.12 GAX18573.1 - 0.0054 16.5 1.4 0.0054 16.5 1.4 2.2 2 0 0 2 2 2 1 PADR1 (NUC008) domain Activator-TraM PF11657.8 GAX18573.1 - 0.017 15.0 0.7 0.017 15.0 0.7 2.3 2 1 0 2 2 2 0 Transcriptional activator TraM DUF3818 PF12825.7 GAX18573.1 - 0.046 12.7 8.5 0.036 13.1 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) zf-BED PF02892.15 GAX18573.1 - 0.085 12.9 0.3 0.25 11.4 0.3 1.8 1 0 0 1 1 1 0 BED zinc finger zinc_ribbon_4 PF13717.6 GAX18573.1 - 0.35 10.8 2.5 3 7.9 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain PT PF04886.12 GAX18576.1 - 6.9e-138 447.9 798.5 6.6e-08 32.0 15.5 40.4 6 4 27 33 33 33 26 PT repeat Acetyltransf_1 PF00583.25 GAX18577.1 - 0.061 13.6 0.5 0.81 9.9 0.5 2.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Gly-zipper_Omp PF13488.6 GAX18577.1 - 0.077 13.0 20.3 0.39 10.8 0.2 3.6 1 1 2 3 3 3 0 Glycine zipper Romo1 PF10247.9 GAX18577.1 - 0.099 13.0 17.6 3.3 8.1 0.3 4.8 1 1 3 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.6 GAX18577.1 - 0.19 11.5 17.9 10 5.9 1.6 3.6 1 1 1 2 2 2 0 YMGG-like Gly-zipper Yae1_N PF09811.9 GAX18577.1 - 0.99 9.2 17.3 4.9 6.9 2.1 4.5 2 1 1 3 3 3 0 Essential protein Yae1, N terminal Transgly_assoc PF04226.13 GAX18577.1 - 1.9 8.8 12.8 0.73 10.1 1.7 3.6 2 1 1 3 3 3 0 Transglycosylase associated protein MtrG PF04210.13 GAX18577.1 - 9.2 6.2 7.9 5 7.1 0.1 2.7 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G PT PF04886.12 GAX18578.1 - 1.5e-68 226.0 310.7 9.5e-07 28.3 15.9 16.4 2 2 9 11 11 11 9 PT repeat Epimerase PF01370.21 GAX18579.1 - 9.8e-26 90.7 0.0 1.8e-25 89.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX18579.1 - 2.3e-16 60.1 0.0 1.5e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX18579.1 - 7e-05 22.1 0.0 0.021 14.0 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 GAX18579.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAGK_cat PF00781.24 GAX18579.1 - 0.031 13.9 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Trypsin PF00089.26 GAX18580.1 - 2.7e-52 177.8 0.0 4e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX18580.1 - 1.2e-08 36.0 0.1 5.1e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Pkinase PF00069.25 GAX18581.1 - 7.5e-54 182.8 0.0 1.1e-53 182.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18581.1 - 2.9e-22 79.2 0.0 6e-22 78.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 GAX18581.1 - 0.00067 20.1 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 GAX18581.1 - 0.0043 16.4 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAX18581.1 - 0.0094 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAX18581.1 - 0.044 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 GAX18581.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GlgX_C PF18390.1 GAX18581.1 - 0.15 11.9 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycogen debranching enzyme C-terminal domain Es2 PF09751.9 GAX18582.1 - 0.0024 17.7 0.6 0.0047 16.7 0.2 1.6 2 0 0 2 2 2 1 Nuclear protein Es2 Par3_HAL_N_term PF12053.8 GAX18582.1 - 0.057 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins TFIIA PF03153.13 GAX18582.1 - 0.11 12.4 8.5 0.15 12.0 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin40_C PF16791.5 GAX18582.1 - 0.7 11.2 5.5 3.7 8.9 4.0 2.8 2 1 0 2 2 2 0 Connexin 40 C-terminal domain DUF2457 PF10446.9 GAX18582.1 - 0.83 8.7 8.1 0.064 12.4 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2457) Aldedh PF00171.22 GAX18583.1 - 1.7e-138 462.0 0.3 2e-138 461.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAX18583.1 - 0.00034 20.1 0.1 0.0044 16.5 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Epimerase PF01370.21 GAX18584.1 - 0.00012 21.6 0.0 0.00038 20.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NARP1 PF12569.8 GAX18586.1 - 0.32 9.8 4.4 0.53 9.1 4.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TRAPP PF04051.16 GAX18587.1 - 3.5e-39 133.8 0.0 4.1e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3624 PF12292.8 GAX18587.1 - 0.16 12.4 0.0 2.4 8.6 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3624) Asr PF06392.11 GAX18588.1 - 0.0084 16.5 1.8 0.025 14.9 1.8 1.8 1 0 0 1 1 1 1 Acid shock protein repeat DUF1269 PF06897.12 GAX18588.1 - 1.8 8.9 7.4 2.6 8.4 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) FA_desaturase PF00487.24 GAX18589.1 - 1.4e-19 70.9 18.9 2.3e-19 70.2 18.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Peptidase_S49 PF01343.18 GAX18590.1 - 2.9e-29 102.0 0.0 5.2e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 GAX18590.1 - 7.5e-05 22.8 4.6 0.00035 20.7 0.2 3.0 2 1 0 2 2 2 1 Peptidase family S49 N-terminal SDH_sah PF01972.16 GAX18590.1 - 0.13 11.2 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Serine dehydrogenase proteinase UPF0020 PF01170.18 GAX18591.1 - 0.0093 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 GAX18591.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 THUMP domain N6_N4_Mtase PF01555.18 GAX18591.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 DNA methylase GxGYxYP_C PF14323.6 GAX18592.1 - 0.069 13.0 0.2 9.7 6.0 0.1 2.3 2 0 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain Glyco_hydro_38N PF01074.22 GAX18593.1 - 5.5e-71 239.3 3.9 7.9e-71 238.8 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAX18593.1 - 2.2e-41 142.3 0.1 3.3e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAX18593.1 - 2.1e-17 63.0 0.0 6.7e-17 61.4 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAX18593.1 - 0.0035 17.4 0.0 0.0089 16.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain SPOB_ab PF14682.6 GAX18593.1 - 0.075 13.1 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal WD40 PF00400.32 GAX18594.1 - 1.1e-10 41.8 1.6 0.22 12.5 0.0 5.3 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX18594.1 - 1.5e-05 25.2 0.0 0.18 12.1 0.0 4.1 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX18594.1 - 0.00096 18.6 0.0 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 GAX18594.1 - 0.0047 15.9 0.0 2.6 6.9 0.0 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 GAX18594.1 - 0.1 13.1 0.4 14 6.3 0.0 3.7 2 1 0 2 2 2 0 PQQ-like domain PAP_fibrillin PF04755.12 GAX18595.1 - 0.00046 20.2 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 PAP_fibrillin Gag_p12 PF01141.18 GAX18595.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 O-FucT PF10250.9 GAX18597.1 - 1.3e-43 150.0 1.1 1.7e-43 149.6 1.1 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 GAX18598.1 - 4.7e-55 187.6 0.6 5.9e-55 187.3 0.6 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Methyltransf_4 PF02390.17 GAX18598.1 - 0.0057 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Glyco_tran_28_C PF04101.16 GAX18599.1 - 1e-23 84.2 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain O-FucT PF10250.9 GAX18600.1 - 4.3e-47 161.4 0.6 5.6e-47 161.1 0.6 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase AATase PF07247.12 GAX18601.1 - 5e-05 22.0 0.5 0.31 9.5 0.4 2.8 3 1 0 3 3 3 2 Alcohol acetyltransferase Condensation PF00668.20 GAX18601.1 - 0.00029 19.7 0.2 0.0033 16.2 0.0 2.5 3 1 0 3 3 3 1 Condensation domain HEAT_2 PF13646.6 GAX18602.1 - 0.00016 22.0 0.3 0.06 13.7 0.2 3.3 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 GAX18602.1 - 0.014 15.4 1.6 0.91 9.5 0.0 3.9 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX18602.1 - 0.022 15.0 6.7 9.8 6.7 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat Adaptin_N PF01602.20 GAX18602.1 - 0.048 12.2 0.1 1.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_PBS PF03130.16 GAX18602.1 - 0.29 11.9 1.1 3.2 8.7 0.1 3.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Tubulin PF00091.25 GAX18604.1 - 9e-57 192.5 0.0 1.5e-56 191.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAX18604.1 - 1.2e-38 132.1 0.1 1.8e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAX18604.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 GAX18604.1 - 0.032 13.4 0.0 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 Tubulin like DUF3309 PF11752.8 GAX18605.1 - 0.8 9.8 3.2 1.3 9.1 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) peroxidase PF00141.23 GAX18607.1 - 1.4e-45 155.8 0.0 2e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Glyco_transf_49 PF13896.6 GAX18608.1 - 5.9e-38 131.0 2.3 8.9e-34 117.3 0.3 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Polyketide_cyc PF03364.20 GAX18609.1 - 6e-18 65.3 0.1 7.7e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAX18609.1 - 0.00029 21.1 0.0 0.00038 20.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CDC27 PF09507.10 GAX18610.1 - 6.9e-18 65.2 26.9 8.4e-18 65.0 26.9 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 NAD_binding_10 PF13460.6 GAX18611.1 - 8.9e-22 77.9 0.0 4.1e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 GAX18611.1 - 8.7e-14 51.6 0.1 2.8e-12 46.7 0.0 2.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 GAX18611.1 - 9.2e-06 25.3 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX18611.1 - 3.5e-05 22.9 0.0 7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 GAX18611.1 - 3.6e-05 23.8 0.2 0.00013 21.9 0.2 1.9 2 0 0 2 2 2 1 KR domain CIA30 PF08547.12 GAX18611.1 - 0.00028 20.9 0.0 0.00059 19.9 0.0 1.5 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Shikimate_DH PF01488.20 GAX18611.1 - 0.002 18.2 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX18611.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAX18611.1 - 0.011 15.2 0.5 0.027 13.9 0.0 2.0 3 0 0 3 3 3 0 short chain dehydrogenase Glu_dehyd_C PF16912.5 GAX18611.1 - 0.028 13.9 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus GDP_Man_Dehyd PF16363.5 GAX18611.1 - 0.1 12.0 0.2 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAX18611.1 - 0.11 11.6 0.0 8.1 5.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX18611.1 - 0.19 10.9 0.4 0.62 9.2 0.3 1.9 2 0 0 2 2 2 0 Male sterility protein mTERF PF02536.14 GAX18612.1 - 3.3e-17 62.4 0.5 1.1e-16 60.7 0.5 1.8 1 1 0 1 1 1 1 mTERF GTA_holin_3TM PF11351.8 GAX18613.1 - 0.13 12.8 0.4 0.42 11.2 0.0 2.1 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Pex14_N PF04695.13 GAX18613.1 - 8.6 7.0 9.6 30 5.2 0.1 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TLC PF03219.14 GAX18615.1 - 1.3e-16 60.4 12.6 6.8e-08 31.7 0.2 3.0 1 1 1 2 2 2 2 TLC ATP/ADP transporter Ninjurin PF04923.12 GAX18615.1 - 0.025 14.5 2.4 5.1 7.1 0.4 2.8 2 1 0 2 2 2 0 Ninjurin COX6A PF02046.15 GAX18615.1 - 0.042 14.3 1.4 5 7.6 0.2 3.1 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VIa HPP PF04982.13 GAX18615.1 - 1.8 8.7 7.5 6.3 7.0 0.9 3.4 3 0 0 3 3 3 0 HPP family LRR_8 PF13855.6 GAX18616.1 - 2.8e-11 43.0 14.4 7e-07 28.9 4.9 2.3 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 GAX18616.1 - 4.7e-08 33.2 7.2 0.0021 18.4 2.7 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX18616.1 - 0.0002 21.5 2.8 2.1 9.2 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 GAX18616.1 - 0.0044 16.6 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 GAX18616.1 - 0.019 15.0 3.6 0.86 9.8 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat ATP19 PF11022.8 GAX18616.1 - 0.058 13.8 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 ATP synthase subunit K PBP_N PF17093.5 GAX18616.1 - 0.097 12.9 0.4 0.21 11.8 0.2 1.7 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus LRRNT_2 PF08263.12 GAX18616.1 - 0.16 12.3 5.7 0.37 11.1 5.7 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Pkinase PF00069.25 GAX18617.1 - 3.7e-09 36.3 0.0 1.7e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18617.1 - 1.1e-08 34.7 0.0 2.7e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase COX6B PF02297.17 GAX18617.1 - 0.19 12.0 0.2 0.19 12.0 0.2 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 GAX18617.1 - 6.6 7.1 10.1 3 8.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) dsrm PF00035.26 GAX18618.1 - 2.6e-12 47.3 0.0 2.3e-07 31.4 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif MCD_N PF17408.2 GAX18618.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain AvrPto PF11592.8 GAX18620.1 - 0.0064 16.5 0.1 1.2 9.3 0.0 2.3 2 0 0 2 2 2 2 Central core of the bacterial effector protein AvrPto HAD PF12710.7 GAX18621.1 - 1.9e-15 57.8 0.0 2.9e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX18621.1 - 1.2e-11 45.4 0.5 1.2e-10 42.1 0.5 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAX18621.1 - 4.6e-08 32.8 0.0 7.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 GAX18621.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF1378 PF07125.11 GAX18621.1 - 0.36 11.0 1.0 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1378) IZUMO PF15005.6 GAX18622.1 - 0.036 14.6 0.0 7.3 7.1 0.0 3.0 3 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated LOR PF04525.12 GAX18623.1 - 8.5e-13 48.3 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related Scramblase PF03803.15 GAX18623.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Scramblase Thiolase_N PF00108.23 GAX18625.1 - 1.7e-70 237.4 0.6 2.5e-70 236.8 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAX18625.1 - 1.8e-34 118.0 0.0 5.5e-34 116.5 0.0 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAX18625.1 - 0.003 17.2 3.8 0.0066 16.1 1.7 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 GAX18625.1 - 0.0064 15.2 0.1 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 GAX18625.1 - 0.084 12.7 2.6 2.6 8.0 0.8 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Hexapep PF00132.24 GAX18626.1 - 3e-14 52.1 3.3 4.9e-10 38.7 0.3 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 GAX18626.1 - 1.4e-13 51.2 0.0 3.5e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 GAX18626.1 - 1.6e-07 31.0 7.0 2.6e-07 30.3 0.5 2.4 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase ACP_PD PF04336.12 GAX18626.1 - 0.023 15.1 0.1 0.056 13.9 0.1 1.6 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase GA PF01468.17 GAX18626.1 - 0.073 13.4 0.4 0.073 13.4 0.4 1.7 2 0 0 2 2 2 0 GA module TPR_1 PF00515.28 GAX18627.1 - 4.3e-11 42.1 7.8 0.00023 20.8 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18627.1 - 2.8e-10 39.5 4.5 0.0059 16.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX18627.1 - 1.3e-08 35.0 3.0 7.3e-06 26.2 0.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18627.1 - 5.2e-07 29.4 2.3 0.02 15.1 0.0 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18627.1 - 9.5e-06 25.2 3.3 0.0047 16.6 0.0 2.8 2 1 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 GAX18627.1 - 2.2e-05 24.9 0.9 2.2e-05 24.9 0.9 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18627.1 - 6.2e-05 23.6 1.5 0.0029 18.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX18627.1 - 0.00047 20.2 1.6 0.021 14.9 0.7 2.6 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 GAX18627.1 - 0.00063 20.3 4.9 0.19 12.6 0.0 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX18627.1 - 0.0012 19.0 0.2 0.0035 17.5 0.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 CAP_C PF08603.11 GAX18627.1 - 0.0036 16.9 0.3 0.0073 15.9 0.3 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TPR_17 PF13431.6 GAX18627.1 - 0.017 15.5 0.1 2.4 8.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18627.1 - 0.019 14.8 0.3 0.85 9.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAX18627.1 - 0.019 15.3 0.2 0.019 15.3 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX18627.1 - 0.033 14.3 0.1 0.073 13.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX18627.1 - 0.058 14.1 2.7 0.97 10.2 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF1376 PF07120.11 GAX18627.1 - 0.11 12.8 1.7 1.2 9.5 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1376) TBCC PF07986.12 GAX18627.1 - 0.16 11.7 1.8 0.33 10.7 1.8 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C MtaB PF12176.8 GAX18627.1 - 0.31 9.8 10.1 0.25 10.1 1.7 2.1 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit DUF3107 PF11305.8 GAX18627.1 - 2.3 8.6 5.9 20 5.6 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) EF-hand_7 PF13499.6 GAX18629.1 - 2.1e-11 44.1 0.1 3.4e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair COPI_assoc PF08507.10 GAX18629.1 - 8.2e-10 38.8 8.9 1.3e-09 38.2 8.9 1.3 1 0 0 1 1 1 1 COPI associated protein EF-hand_6 PF13405.6 GAX18629.1 - 1.4e-06 27.8 0.1 0.00055 19.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Cg6151-P PF10233.9 GAX18629.1 - 2.3e-05 24.7 5.9 3.9e-05 23.9 5.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P EF-hand_1 PF00036.32 GAX18629.1 - 4.3e-05 22.8 0.1 0.0027 17.1 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GAX18629.1 - 0.0019 17.6 0.1 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 GAX18629.1 - 0.037 14.3 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.25 GAX18630.1 - 3e-56 190.7 0.0 1.3e-54 185.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18630.1 - 1.6e-29 103.0 0.0 3.4e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX18630.1 - 1.8e-15 57.1 4.6 3.7e-10 40.1 1.3 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX18630.1 - 5.8e-11 41.4 5.1 0.0019 18.0 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 GAX18630.1 - 1.1e-10 40.3 7.7 0.05 13.2 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAX18630.1 - 2.8e-09 36.7 0.9 0.0012 18.7 0.0 3.2 2 2 2 4 4 4 2 EF-hand domain pair Pkinase_fungal PF17667.1 GAX18630.1 - 1.2e-06 27.5 0.0 1.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX18630.1 - 0.00015 21.2 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX18630.1 - 0.00077 18.9 0.0 0.003 16.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAX18630.1 - 0.0078 16.2 0.1 0.033 14.1 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAX18630.1 - 0.03 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Haspin_kinase PF12330.8 GAX18630.1 - 0.059 12.3 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain WD40_alt PF14077.6 GAX18630.1 - 0.22 11.4 1.2 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif TPR_1 PF00515.28 GAX18631.1 - 0.046 13.6 1.2 23 5.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18631.1 - 0.11 12.6 0.5 5.5 7.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 GAX18632.1 - 1.4e-06 29.2 0.0 3.9e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold KaiA PF07688.12 GAX18632.1 - 0.014 15.5 0.1 5.8 7.1 0.0 2.4 2 0 0 2 2 2 0 KaiA C-terminal domain CoA_binding_2 PF13380.6 GAX18632.1 - 0.03 14.8 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain PDZ PF00595.24 GAX18635.1 - 3.2e-09 37.0 0.1 6.6e-09 36.0 0.1 1.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX18635.1 - 1.2e-07 31.5 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX18635.1 - 0.00019 21.7 0.0 0.00036 20.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Glyco_tranf_2_4 PF13704.6 GAX18637.1 - 2.2e-06 28.1 1.8 4.9e-06 27.0 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX18637.1 - 0.0021 17.8 1.5 0.0027 17.4 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 92 Sulfotransfer_2 PF03567.14 GAX18638.1 - 4.1e-07 30.2 0.5 2.1e-06 27.8 1.0 1.8 2 1 0 2 2 2 1 Sulfotransferase family RuvX PF03652.15 GAX18639.1 - 0.0014 19.0 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction resolvase zf-RING_2 PF13639.6 GAX18640.1 - 4e-13 49.5 5.4 6.3e-13 48.8 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX18640.1 - 6.3e-11 41.9 3.9 9.8e-11 41.3 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX18640.1 - 1.2e-09 37.7 2.8 1.2e-09 37.7 2.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 GAX18640.1 - 3.2e-09 36.9 5.2 6.8e-09 35.9 5.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX18640.1 - 2.1e-08 34.0 3.6 3.3e-08 33.4 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX18640.1 - 2.5e-08 33.8 2.5 4.7e-08 32.9 0.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX18640.1 - 4.2e-08 32.9 4.1 6.7e-08 32.3 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX18640.1 - 2.5e-05 24.0 3.9 3.7e-05 23.5 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX18640.1 - 0.002 18.1 3.4 0.0048 16.9 3.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAX18640.1 - 0.0032 17.3 5.0 0.0056 16.5 5.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-HC5HC2H_2 PF13832.6 GAX18640.1 - 0.013 15.6 1.1 0.023 14.9 1.1 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.7 GAX18640.1 - 0.048 13.8 4.6 0.13 12.4 4.5 1.8 1 1 0 1 1 1 0 RING-variant domain CBP4 PF07960.11 GAX18640.1 - 0.079 12.8 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 CBP4 zf-C3H2C3 PF17122.5 GAX18640.1 - 0.083 12.9 1.3 0.21 11.6 1.3 1.7 1 1 0 1 1 1 0 Zinc-finger RecR PF02132.15 GAX18640.1 - 0.094 12.3 0.8 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 RecR protein Zn_ribbon_17 PF17120.5 GAX18640.1 - 0.11 12.2 5.7 0.18 11.4 5.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAX18640.1 - 0.14 12.0 3.4 0.37 10.6 3.5 1.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAX18640.1 - 0.35 11.1 3.6 1.1 9.5 3.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 GAX18640.1 - 0.54 10.5 7.3 0.077 13.2 1.7 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 GAX18640.1 - 0.86 10.0 3.5 1.4 9.2 3.5 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 GAX18640.1 - 1.1 9.2 4.0 2.3 8.2 4.0 1.6 1 1 0 1 1 1 0 PHD-finger Mitofilin PF09731.9 GAX18641.1 - 0.00069 18.6 34.0 0.00069 18.6 34.0 2.0 1 1 1 2 2 2 1 Mitochondrial inner membrane protein Effector_1 PF04518.12 GAX18641.1 - 0.001 18.2 7.7 0.001 18.2 7.7 2.2 2 0 0 2 2 2 1 Effector from type III secretion system Tup_N PF08581.10 GAX18641.1 - 0.0017 18.6 14.0 0.0017 18.6 14.0 3.2 3 0 0 3 3 3 2 Tup N-terminal YscO-like PF16789.5 GAX18641.1 - 0.0029 17.7 13.3 0.0029 17.7 13.3 3.1 1 1 2 3 3 3 1 YscO-like protein TMF_TATA_bd PF12325.8 GAX18641.1 - 0.014 15.6 23.4 0.014 15.6 23.4 2.7 1 1 1 2 2 1 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 GAX18641.1 - 0.022 15.2 7.6 0.022 15.2 7.6 4.5 1 1 3 4 4 3 0 Centrosome microtubule-binding domain of Cep57 DASH_Dam1 PF08653.10 GAX18641.1 - 0.022 14.5 6.3 2.4 8.0 2.4 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF3584 PF12128.8 GAX18641.1 - 0.035 11.6 38.7 0.045 11.3 38.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SHE3 PF17078.5 GAX18641.1 - 0.59 9.8 36.1 0.51 10.0 21.5 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Pox_A_type_inc PF04508.12 GAX18641.1 - 1 9.3 8.7 1.7 8.6 0.0 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DASH_Dad4 PF08650.10 GAX18641.1 - 1.1 9.2 12.0 0.27 11.2 5.5 3.0 2 1 1 3 3 3 0 DASH complex subunit Dad4 DUF4795 PF16043.5 GAX18641.1 - 1.4 8.5 44.1 0.72 9.4 1.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF883 PF05957.13 GAX18641.1 - 1.4 9.6 32.1 0.16 12.6 3.4 4.1 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) NPV_P10 PF05531.12 GAX18641.1 - 1.7 9.2 17.2 1 9.9 4.5 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 GAX18641.1 - 1.7 8.8 33.1 0.18 12.0 8.9 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 GAX18641.1 - 1.7 6.7 47.7 0.13 10.4 36.9 2.0 1 1 1 2 2 1 0 HOOK protein GAS PF13851.6 GAX18641.1 - 3 7.2 52.3 0.017 14.5 21.3 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 GAX18641.1 - 8.3 5.6 44.3 0.067 12.5 16.5 3.2 1 1 2 3 3 2 0 Protein of unknown function (DUF3450) YlqD PF11068.8 GAX18641.1 - 8.7 6.7 43.8 0.053 13.9 16.2 3.1 1 1 2 3 3 3 0 YlqD protein Tho2 PF11262.8 GAX18641.1 - 9.9 5.3 32.6 0.17 11.0 12.0 2.3 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Fer2_3 PF13085.6 GAX18642.1 - 5.9e-32 109.9 0.0 9.5e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 GAX18642.1 - 1.6e-09 38.2 4.9 1.6e-09 38.2 4.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAX18642.1 - 1.7e-08 34.8 12.4 4e-08 33.6 7.8 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAX18642.1 - 6.6e-08 32.6 3.6 6.6e-08 32.6 3.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 GAX18642.1 - 0.0024 18.4 7.8 0.0024 18.4 7.8 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 GAX18642.1 - 0.0036 17.2 3.5 0.0046 16.9 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 GAX18642.1 - 0.0056 16.8 7.6 0.0056 16.8 7.6 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 GAX18642.1 - 0.058 13.6 5.9 0.38 11.0 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain TPR_1 PF00515.28 GAX18643.1 - 4 7.4 8.5 42 4.2 0.6 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Ysc84 PF04366.12 GAX18645.1 - 3.8e-42 143.1 0.2 6.3e-42 142.4 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 GAX18645.1 - 3.6e-20 71.9 1.2 3.6e-20 71.9 1.2 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-CRD PF17979.1 GAX18645.1 - 0.032 14.3 0.9 0.032 14.3 0.9 1.8 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions IBR PF01485.21 GAX18645.1 - 0.1 12.9 10.4 0.14 12.4 6.8 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TraT PF05818.12 GAX18645.1 - 0.38 10.4 5.3 0.055 13.1 1.4 1.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein FYVE_2 PF02318.16 GAX18645.1 - 0.64 10.2 5.4 0.37 11.0 2.7 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Abhydrolase_6 PF12697.7 GAX18646.1 - 8.8e-09 36.3 0.8 1.1e-08 36.0 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX18646.1 - 1.2e-05 24.7 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX18646.1 - 0.0006 19.5 0.2 0.23 11.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold cobW PF02492.19 GAX18648.1 - 5.3e-49 166.2 0.1 6.8e-49 165.8 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX18648.1 - 1.1e-21 76.5 0.0 1.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAX18648.1 - 0.0015 18.4 0.1 0.75 9.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 GAX18648.1 - 0.016 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 GAX18648.1 - 0.047 14.0 0.1 0.17 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain dNK PF01712.19 GAX18648.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase ATPase_2 PF01637.18 GAX18648.1 - 0.068 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAX18648.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAX18648.1 - 0.15 12.0 0.1 0.81 9.6 0.1 2.0 2 0 0 2 2 2 0 NTPase Glyco_tranf_2_4 PF13704.6 GAX18649.1 - 3.1e-05 24.4 0.3 7.2e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Pkinase PF00069.25 GAX18650.1 - 7.5e-14 51.7 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18650.1 - 2.7e-11 43.3 0.0 4.1e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 GAX18651.1 - 1.5e-31 109.6 35.8 1.5e-31 109.6 35.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX18651.1 - 4.5e-08 32.4 26.2 5.3e-07 28.9 26.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAX18651.1 - 1.1e-06 27.8 30.7 2.9e-06 26.4 9.5 2.6 1 1 1 2 2 2 2 MFS_1 like family DUF5341 PF17276.2 GAX18651.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5341) ATP-sulfurylase PF01747.17 GAX18652.1 - 2.3e-70 236.4 0.0 3.3e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 GAX18652.1 - 6.3e-41 139.7 0.0 8.9e-41 139.2 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain Cellulase PF00150.18 GAX18654.1 - 4.5e-09 36.2 0.1 8.2e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DNA_ligase_aden PF01653.18 GAX18655.1 - 1.1e-54 185.7 0.0 2e-54 184.8 0.0 1.5 1 1 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 GAX18655.1 - 5.6e-24 83.8 1.7 1.2e-23 82.8 1.7 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain BRCT PF00533.26 GAX18655.1 - 6e-10 39.4 0.0 1.2e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAX18655.1 - 0.00012 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain HHH_2 PF12826.7 GAX18655.1 - 0.0099 16.0 0.1 0.05 13.7 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_ligase_ZBD PF03119.16 GAX18655.1 - 0.021 14.8 3.3 0.037 14.0 1.5 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain HHH_5 PF14520.6 GAX18655.1 - 0.058 14.0 0.0 5.1 7.8 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain Myosin_head PF00063.21 GAX18656.1 - 3.9e-193 643.4 0.8 1.3e-176 588.7 0.1 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) CBS PF00571.28 GAX18656.1 - 3e-51 171.7 27.0 3.3e-08 33.9 0.7 10.7 10 0 0 10 10 10 8 CBS domain PB1 PF00564.24 GAX18656.1 - 1e-09 38.2 0.0 3.2e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.6 GAX18657.1 - 6.2e-15 55.3 2.2 4.8e-06 26.8 0.2 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18657.1 - 2.2e-11 43.0 0.5 0.043 13.6 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX18657.1 - 1.2e-08 34.3 1.3 0.41 10.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18657.1 - 2.1e-08 33.7 1.8 0.12 12.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18657.1 - 0.0001 22.2 3.5 3.6 8.0 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18657.1 - 0.00033 21.2 6.1 15 6.7 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2225 PF09986.9 GAX18657.1 - 0.00049 19.9 3.6 0.0018 18.1 1.6 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 GAX18657.1 - 0.00092 19.0 2.6 9.1 6.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 GAX18657.1 - 0.0017 18.4 0.8 0.0047 17.0 0.4 1.9 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 GAX18657.1 - 0.0036 17.0 2.2 5.2 6.8 0.0 3.8 3 2 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 GAX18657.1 - 0.027 15.1 3.7 2.2 9.0 0.8 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1445 PF07286.12 GAX18657.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) PCRF PF03462.18 GAX18657.1 - 0.83 9.5 5.3 0.17 11.8 1.2 1.8 2 0 0 2 2 2 0 PCRF domain TPR_6 PF13174.6 GAX18657.1 - 1.2 9.9 3.3 16 6.4 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DHBP_synthase PF00926.19 GAX18658.1 - 1e-75 253.5 0.7 1.7e-75 252.8 0.7 1.4 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 GAX18658.1 - 4.9e-56 188.8 0.0 1.3e-55 187.5 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase II MIF4G PF02854.19 GAX18659.1 - 0.0013 18.4 0.0 0.26 10.9 0.0 2.8 2 1 0 2 2 2 2 MIF4G domain MA3 PF02847.17 GAX18659.1 - 0.0044 17.0 0.1 0.43 10.6 0.0 2.6 2 0 0 2 2 2 2 MA3 domain PH PF00169.29 GAX18660.1 - 1.2e-14 54.7 0.1 1.7e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 PH domain TFIIA PF03153.13 GAX18660.1 - 1.6e-05 25.1 18.2 2.3e-05 24.6 18.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PH_11 PF15413.6 GAX18660.1 - 0.00015 22.1 3.1 0.0027 18.1 3.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAX18660.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 GAX18660.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 GAX18661.1 - 5.7e-59 199.6 0.1 8.9e-59 199.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18661.1 - 2.1e-29 102.6 0.0 3.4e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX18661.1 - 8.3e-18 64.6 0.6 1.3e-08 35.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX18661.1 - 2.5e-14 51.7 0.1 0.0052 16.2 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAX18661.1 - 2.6e-14 51.8 0.4 0.002 17.9 0.1 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 GAX18661.1 - 9.3e-14 51.0 0.3 3.6e-07 29.9 0.0 3.9 2 2 2 4 4 4 2 EF-hand domain pair Pkinase_fungal PF17667.1 GAX18661.1 - 1.6e-05 23.8 0.0 2.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX18661.1 - 4e-05 23.1 0.0 0.00017 21.1 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_5 PF13202.6 GAX18661.1 - 7.7e-05 22.0 0.4 1.2 8.8 0.1 3.8 3 0 0 3 3 3 2 EF hand DUF1296 PF06972.11 GAX18661.1 - 0.00041 20.4 0.0 0.00093 19.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) Kinase-like PF14531.6 GAX18661.1 - 0.0011 18.4 0.1 0.0051 16.2 0.1 2.0 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAX18661.1 - 0.0019 17.2 0.1 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Cellulase PF00150.18 GAX18662.1 - 0.00029 20.4 0.8 0.049 13.1 0.0 3.4 2 2 1 3 3 3 3 Cellulase (glycosyl hydrolase family 5) PhyH PF05721.13 GAX18663.1 - 8.4e-06 26.2 0.1 1.7e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Guanylate_cyc PF00211.20 GAX18664.1 - 3.6e-12 46.3 0.1 7.4e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain IQ PF00612.27 GAX18664.1 - 0.0067 16.1 1.8 0.023 14.5 1.8 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Big_3_2 PF12245.8 GAX18664.1 - 0.068 13.4 0.3 0.46 10.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain ATPase PF06745.13 GAX18666.1 - 0.22 10.9 0.0 0.47 9.8 0.0 1.5 2 0 0 2 2 2 0 KaiC DnaJ PF00226.31 GAX18667.1 - 0.011 15.9 0.1 0.041 14.0 0.0 2.1 2 1 0 2 2 2 0 DnaJ domain TFIIA PF03153.13 GAX18668.1 - 0.022 14.8 9.4 0.026 14.5 9.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNase PF00565.17 GAX18669.1 - 4.5e-17 62.5 0.0 7.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF3664 PF12406.8 GAX18669.1 - 0.11 13.1 0.6 0.11 13.1 0.6 1.7 2 0 0 2 2 2 0 Surface protein Pro_isomerase PF00160.21 GAX18670.1 - 1.4e-15 57.9 0.0 2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DNA_ligase_A_M PF01068.21 GAX18672.1 - 4.6e-22 78.7 0.0 2.8e-17 63.1 0.0 3.4 3 1 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAX18672.1 - 4.9e-21 75.8 0.0 1.1e-20 74.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAX18672.1 - 3.9e-06 27.4 0.0 0.00015 22.3 0.0 3.0 1 1 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 GAX18672.1 - 4.8e-05 23.7 0.0 0.00032 21.1 0.0 2.3 1 1 0 1 1 1 1 RNA ligase PTCB-BRCT PF12738.7 GAX18672.1 - 0.14 12.2 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain RNase_T PF00929.24 GAX18673.1 - 2.2e-06 28.3 0.0 4.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAX18673.1 - 0.0094 15.7 0.2 0.054 13.2 0.2 2.1 1 1 0 1 1 1 1 3'-5' exonuclease GTA_holin_3TM PF11351.8 GAX18673.1 - 4.5 7.8 5.6 4.8 7.8 0.7 2.5 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Nuf2 PF03800.14 GAX18674.1 - 5.1e-33 114.1 0.0 5.1e-33 114.1 0.0 2.7 3 0 0 3 3 3 1 Nuf2 family DUF2999 PF11212.8 GAX18674.1 - 0.13 12.6 2.3 1.9 8.8 0.0 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF2999) LytR_C PF13399.6 GAX18674.1 - 3.8 8.6 5.3 0.86 10.6 0.5 2.3 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator MBD PF01429.19 GAX18675.1 - 8.3e-08 31.8 0.4 2.5e-07 30.3 0.4 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain MAS20 PF02064.15 GAX18675.1 - 0.59 10.2 4.3 1.6 8.8 4.3 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor adh_short PF00106.25 GAX18676.1 - 3.4e-40 137.6 0.0 4.2e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX18676.1 - 1.8e-28 99.7 0.0 2.3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX18676.1 - 2.3e-19 70.0 0.2 3e-19 69.6 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX18676.1 - 8.5e-05 22.1 0.1 0.00091 18.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAX18676.1 - 0.0025 17.0 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 GAX18676.1 - 0.017 14.4 0.1 0.03 13.6 0.0 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 GAX18676.1 - 0.059 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Exo_endo_phos PF03372.23 GAX18677.1 - 8.6e-14 51.6 0.9 1.4e-13 50.9 0.9 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAX18677.1 - 0.0015 18.3 0.0 0.23 11.3 0.0 2.8 2 1 0 2 2 2 2 Endonuclease-reverse transcriptase DUF4017 PF13209.6 GAX18677.1 - 0.12 12.3 0.4 0.21 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) Dis3l2_C_term PF17877.1 GAX18678.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal RII_binding_1 PF10522.9 GAX18678.1 - 0.47 10.8 1.6 1.1 9.6 1.6 1.6 1 0 0 1 1 1 0 RII binding domain F-box-like PF12937.7 GAX18679.1 - 3e-06 27.0 0.0 7.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAX18679.1 - 0.00019 21.2 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain SQHop_cyclase_N PF13249.6 GAX18680.1 - 9.6e-52 175.9 0.1 6.5e-44 150.2 0.1 4.3 4 1 0 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 GAX18680.1 - 1.4e-50 172.2 1.1 1.6e-43 149.1 0.2 3.0 2 2 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 GAX18680.1 - 3.3e-28 97.1 25.7 4.2e-07 29.6 2.7 7.5 6 2 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 GAX18680.1 - 1.7e-05 24.3 0.0 1 8.6 0.0 3.6 3 0 0 3 3 3 2 Pectic acid lyase TED_complement PF07678.14 GAX18680.1 - 0.018 14.1 0.0 0.72 8.8 0.0 3.1 3 0 0 3 3 3 0 A-macroglobulin TED domain M20_dimer PF07687.14 GAX18680.1 - 0.21 11.5 0.0 1.1e+02 2.8 0.0 3.5 4 0 0 4 4 4 0 Peptidase dimerisation domain PDEase_I PF00233.19 GAX18681.1 - 1.4e-31 110.1 0.6 1.1e-30 107.2 0.6 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 GAX18682.1 - 4.3e-10 39.2 44.4 5.3e-06 25.8 11.0 2.6 2 1 0 2 2 2 2 Ion transport protein DUF3592 PF12158.8 GAX18682.1 - 3 7.9 4.4 14 5.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3592) KIX_2 PF16987.5 GAX18683.1 - 1.9e-07 31.0 0.3 6.8e-07 29.2 0.3 2.0 1 0 0 1 1 1 1 KIX domain Flagellin_C PF00700.21 GAX18683.1 - 0.053 13.9 0.3 0.32 11.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF4253 PF14062.6 GAX18683.1 - 0.082 13.1 0.1 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) FapA PF03961.13 GAX18683.1 - 0.6 8.7 3.1 0.72 8.4 0.2 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A GCIP PF13324.6 GAX18684.1 - 1.1e-30 107.1 0.3 1.9e-30 106.3 0.3 1.4 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Glutaredoxin2_C PF04399.13 GAX18684.1 - 0.0024 17.7 0.4 0.0071 16.2 0.1 1.9 2 0 0 2 2 2 1 Glutaredoxin 2, C terminal domain UPF0565 PF10561.9 GAX18684.1 - 0.059 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Spc29 PF17082.5 GAX18684.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 GFA PF04828.14 GAX18685.1 - 0.0088 16.4 0.6 1.1 9.6 0.0 3.4 2 1 1 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme Auxin_repressed PF05564.12 GAX18685.1 - 6.3 7.5 8.3 1 10.1 1.8 2.4 1 1 1 2 2 2 0 Dormancy/auxin associated protein RNA_pol_A_bac PF01000.26 GAX18686.1 - 5.2e-25 88.0 0.0 2.2e-24 86.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAX18686.1 - 2e-18 65.6 0.0 3.5e-18 64.8 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rieske PF00355.26 GAX18688.1 - 7.1e-12 45.1 0.0 1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 GAX18688.1 - 1.8e-10 40.7 2.1 2.7e-10 40.1 0.2 2.1 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit NTP_transf_3 PF12804.7 GAX18689.1 - 6.1e-08 33.2 0.1 1.4e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 GAX18689.1 - 1.8e-07 30.6 5.8 2.4e-05 23.8 1.7 3.7 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 GAX18689.1 - 1.6e-06 27.9 0.0 4.2e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 GAX18689.1 - 0.0038 15.4 1.4 0.12 10.5 1.4 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) Fucokinase PF07959.12 GAX18689.1 - 0.023 13.7 0.2 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 L-fucokinase ALG11_N PF15924.5 GAX18690.1 - 6.9e-64 215.7 0.2 9.6e-64 215.3 0.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 GAX18690.1 - 5.4e-11 42.3 0.0 8.6e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 GAX18690.1 - 0.00019 20.3 0.0 0.00049 18.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 20 Glyco_transf_4 PF13439.6 GAX18690.1 - 0.0017 18.4 0.3 0.0085 16.1 0.3 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Ammonium_transp PF00909.21 GAX18691.1 - 1e-104 350.4 27.1 1.2e-104 350.2 27.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Baculo_11_kDa PF06143.11 GAX18691.1 - 6 6.5 5.1 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family LRR_8 PF13855.6 GAX18692.1 - 2.3e-11 43.3 0.6 4.7e-06 26.3 1.6 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX18692.1 - 1.5e-05 25.2 2.0 0.043 14.3 1.0 2.8 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX18692.1 - 0.045 14.1 0.5 0.084 13.2 0.5 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GAX18692.1 - 0.17 12.5 0.9 28 5.8 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat TMEM144 PF07857.12 GAX18693.1 - 1.4e-20 73.6 17.9 8.9e-15 54.5 0.2 2.5 2 1 0 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 GAX18693.1 - 4.5e-11 42.6 18.0 6.3e-09 35.6 1.2 2.9 3 0 0 3 3 3 2 Sugar transport protein Ureide_permease PF07168.11 GAX18693.1 - 0.0039 16.0 11.9 0.12 11.2 3.6 2.5 2 0 0 2 2 2 2 Ureide permease SPC25 PF06703.11 GAX18693.1 - 5.4 6.8 5.3 0.71 9.7 0.1 2.2 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PUB PF09409.10 GAX18694.1 - 2.3e-19 69.1 0.3 6.4e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 PUB domain Thioredoxin PF00085.20 GAX18694.1 - 6.9e-12 45.3 0.0 1.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin zf-C2H2 PF00096.26 GAX18694.1 - 0.004 17.5 0.1 0.009 16.4 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type Thioredoxin_2 PF13098.6 GAX18694.1 - 0.027 14.9 2.6 1.1 9.8 0.1 3.4 2 2 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX18694.1 - 0.028 14.8 0.0 0.39 11.1 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX18694.1 - 0.031 14.0 0.0 0.031 14.0 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin DUF2115 PF09888.9 GAX18694.1 - 1.4 9.4 6.9 3.1 8.3 6.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) UPF0242 PF06785.11 GAX18694.1 - 3.5 7.7 13.5 7.7 6.6 13.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3435 PF11917.8 GAX18694.1 - 5.6 5.8 14.8 8.7 5.2 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Cytochrom_C PF00034.21 GAX18695.1 - 2.5e-13 51.0 0.1 3.9e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GAX18695.1 - 6.5e-06 26.4 1.5 2.1e-05 24.7 1.5 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAX18695.1 - 0.0037 17.0 0.4 0.028 14.2 0.2 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.6 GAX18695.1 - 0.054 13.5 0.6 0.078 12.9 0.1 1.4 2 0 0 2 2 2 0 Haem-binding domain Cytochrome_P460 PF16694.5 GAX18695.1 - 0.07 13.5 0.7 7.9 6.8 0.2 2.1 2 0 0 2 2 2 0 Cytochrome P460 WD40 PF00400.32 GAX18696.1 - 1.8e-14 53.9 10.0 6.9e-05 23.5 0.4 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX18696.1 - 1.3e-07 31.8 0.1 0.00012 22.3 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX18696.1 - 7.9e-05 22.6 0.0 0.043 13.7 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ssu72 PF04722.13 GAX18696.1 - 0.11 12.1 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Ssu72-like protein PCI PF01399.27 GAX18697.1 - 1.3e-07 32.1 0.1 2.7e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 PCI domain PA PF02225.22 GAX18698.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 PA domain SSF PF00474.17 GAX18699.1 - 4.2e-20 72.0 16.6 2.8e-17 62.7 9.6 2.2 2 0 0 2 2 2 2 Sodium:solute symporter family DEAD PF00270.29 GAX18700.1 - 1e-45 155.7 0.0 3.3e-45 154.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX18700.1 - 4.1e-22 78.6 0.0 1.4e-21 77.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAX18700.1 - 7.4e-13 48.5 2.0 9.9e-13 48.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) DUF5023 PF16426.5 GAX18700.1 - 0.0081 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5023) Barttin PF15462.6 GAX18700.1 - 0.72 9.6 4.6 0.38 10.5 1.7 1.9 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) SSF PF00474.17 GAX18701.1 - 7.8e-23 81.0 17.7 8.4e-20 71.0 11.4 2.2 2 0 0 2 2 2 2 Sodium:solute symporter family SURF6 PF04935.12 GAX18702.1 - 3e-23 82.7 46.7 3e-23 82.7 46.7 2.2 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 GAX18702.1 - 3.2e-13 50.1 0.1 3.2e-13 50.1 0.1 5.1 3 2 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 DUF2486 PF10667.9 GAX18702.1 - 0.013 15.7 12.3 0.013 15.7 12.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) Peptidase_S8 PF00082.22 GAX18703.1 - 1.1e-37 129.9 1.5 1.6e-25 90.0 0.2 2.1 2 0 0 2 2 2 2 Subtilase family PA PF02225.22 GAX18703.1 - 8.2e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF2150 PF09920.9 GAX18703.1 - 0.21 11.6 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Rubis-subs-bind PF09273.11 GAX18704.1 - 1.6e-24 87.0 0.0 2.9e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 GAX18704.1 - 7.8e-15 55.7 0.0 1.5e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Nop53 PF07767.11 GAX18705.1 - 1.9e-33 116.5 39.8 4.7e-33 115.1 39.8 1.7 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) WD40 PF00400.32 GAX18706.1 - 3.4e-34 116.3 21.6 1.6e-05 25.6 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX18706.1 - 2.8e-08 33.9 0.8 7.9 6.8 0.0 5.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAX18706.1 - 0.055 13.0 0.6 0.6 9.6 0.5 2.4 1 1 1 2 2 2 0 PQQ-like domain DUF3952 PF13130.6 GAX18706.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) ABC1 PF03109.16 GAX18707.1 - 1.1e-23 83.6 0.0 2.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX18707.1 - 2.7e-08 34.0 1.3 5.3e-06 26.5 1.3 3.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX18707.1 - 1e-05 25.0 0.0 3e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF285 PF03382.14 GAX18708.1 - 1e-81 270.6 37.8 7.2e-32 109.7 6.0 3.4 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 Bromodomain PF00439.25 GAX18708.1 - 0.16 12.1 0.4 14 5.8 0.0 3.8 4 0 0 4 4 4 0 Bromodomain DrrA_P4M PF14860.6 GAX18708.1 - 0.24 11.3 3.9 28 4.6 0.2 4.1 3 2 1 4 4 4 0 DrrA phosphatidylinositol 4-phosphate binding domain Bromodomain PF00439.25 GAX18709.1 - 9.2e-95 310.9 5.8 5e-16 58.5 0.1 6.6 6 0 0 6 6 6 6 Bromodomain Acyltransferase PF01553.21 GAX18710.1 - 1.7e-07 30.9 0.0 3.4e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase SRC-1 PF08832.10 GAX18711.1 - 0.03 15.4 0.2 0.073 14.1 0.0 1.7 2 0 0 2 2 2 0 Steroid receptor coactivator PseudoU_synth_2 PF00849.22 GAX18712.1 - 0.03 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase JmjC PF02373.22 GAX18713.1 - 3e-35 121.1 0.1 6e-35 120.1 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 GAX18713.1 - 6.8e-12 45.6 14.8 1.5e-11 44.5 14.8 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.17 GAX18713.1 - 7.3e-12 45.0 0.5 1.4e-11 44.1 0.5 1.5 1 0 0 1 1 1 1 jmjN domain DUF1129 PF06570.11 GAX18715.1 - 0.11 11.9 2.6 0.23 10.9 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PCAF_N PF06466.11 GAX18716.1 - 0.0014 18.3 0.1 0.012 15.2 0.0 2.0 1 1 1 2 2 2 1 PCAF (P300/CBP-associated factor) N-terminal domain An_peroxidase PF03098.15 GAX18717.1 - 3.3e-84 283.4 1.1 1.1e-72 245.3 0.2 2.3 1 1 1 2 2 2 2 Animal haem peroxidase Trypsin PF00089.26 GAX18718.1 - 2.4e-34 119.1 0.0 4e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Topoisom_I_N PF02919.15 GAX18719.1 - 0.067 12.7 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment FHA PF00498.26 GAX18721.1 - 8.8e-18 64.4 0.0 1.5e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAX18721.1 - 6.5e-08 32.8 0.0 2.9e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SR-25 PF10500.9 GAX18721.1 - 0.021 14.4 10.5 0.025 14.2 10.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 GAX18721.1 - 3 7.1 6.6 3.9 6.7 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPR3 PF03666.13 GAX18721.1 - 4.7 5.9 6.4 5.4 5.7 6.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Chloroa_b-bind PF00504.21 GAX18724.1 - 7.6e-26 91.6 0.0 9.4e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Rhodanese PF00581.20 GAX18725.1 - 1.1e-07 32.4 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 GAX18725.1 - 0.00037 20.5 0.2 0.015 15.3 0.2 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF442 PF04273.13 GAX18725.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Guanylate_kin PF00625.21 GAX18725.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Guanylate kinase Patatin PF01734.22 GAX18726.1 - 1.5e-20 74.3 0.0 4.8e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase LRRFIP PF09738.9 GAX18726.1 - 0.0011 18.6 2.6 0.0018 17.8 2.6 1.3 1 0 0 1 1 1 1 LRRFIP family HAP1_N PF04849.13 GAX18726.1 - 0.0076 15.5 2.6 0.014 14.6 2.6 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF3336 PF11815.8 GAX18726.1 - 0.011 15.5 0.0 0.011 15.5 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3336) DUF4763 PF15960.5 GAX18726.1 - 0.013 14.8 2.8 0.025 13.9 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) AATF-Che1 PF13339.6 GAX18726.1 - 0.038 14.7 4.4 0.36 11.5 2.1 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Plk4_PB2 PF18409.1 GAX18726.1 - 0.04 14.6 0.1 0.12 13.0 0.1 1.8 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 bZIP_2 PF07716.15 GAX18726.1 - 0.11 12.7 3.1 0.24 11.5 3.1 1.6 1 0 0 1 1 1 0 Basic region leucine zipper YabA PF06156.13 GAX18726.1 - 0.88 10.2 4.0 2.8 8.7 4.0 1.8 1 0 0 1 1 1 0 Initiation control protein YabA GIT_CC PF16559.5 GAX18726.1 - 0.94 9.4 6.6 2.3 8.2 6.6 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4191 PF13829.6 GAX18726.1 - 1.2 8.4 4.7 2.5 7.4 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) E2F_CC-MB PF16421.5 GAX18726.1 - 1.7 9.1 8.7 72 3.8 0.0 3.5 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain TLD PF07534.16 GAX18727.1 - 4.9e-21 75.4 0.0 8.3e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 TLD S6PP_C PF08472.10 GAX18727.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal PAS PF00989.25 GAX18728.1 - 4.9e-06 26.5 0.0 9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold bZIP_1 PF00170.21 GAX18728.1 - 8.7e-06 25.7 6.7 1.9e-05 24.7 6.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor PAS_4 PF08448.10 GAX18728.1 - 0.00011 22.4 0.0 0.00034 20.8 0.0 1.8 2 1 1 3 3 3 1 PAS fold PAS_9 PF13426.7 GAX18728.1 - 0.00027 21.1 0.0 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain bZIP_2 PF07716.15 GAX18728.1 - 0.00031 20.8 9.8 0.00076 19.5 9.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PGA2 PF07543.12 GAX18728.1 - 0.0053 16.7 1.2 0.0053 16.7 1.2 1.8 2 0 0 2 2 2 1 Protein trafficking PGA2 PAS_3 PF08447.12 GAX18728.1 - 0.018 15.3 0.0 0.051 13.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 GAX18728.1 - 0.032 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 PAS domain Aminotran_5 PF00266.19 GAX18729.1 - 6.6e-60 203.0 0.1 7.8e-60 202.8 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAX18729.1 - 1.2e-08 34.6 0.2 2.1e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 GAX18729.1 - 0.00019 20.3 0.0 0.00029 19.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 GAX18729.1 - 0.00024 20.5 0.2 0.00044 19.7 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 GAX18729.1 - 0.0037 16.2 0.1 0.007 15.2 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 GAX18729.1 - 0.022 13.3 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DPRP PF04244.13 GAX18729.1 - 0.036 13.9 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein Arena_nucleocap PF00843.17 GAX18729.1 - 0.094 11.6 0.1 4.8 6.0 0.1 2.1 2 0 0 2 2 2 0 Arenavirus nucleocapsid N-terminal domain Rhodanese PF00581.20 GAX18730.1 - 1.6e-07 31.8 0.0 2.6e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 GAX18730.1 - 0.0093 16.0 0.0 0.042 13.8 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAX18730.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 GAX18730.1 - 0.045 13.8 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Aminotran_1_2 PF00155.21 GAX18731.1 - 1.4e-47 162.7 0.0 1.9e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PPC PF04151.15 GAX18732.1 - 0.00031 21.8 0.1 0.00078 20.5 0.1 1.6 1 1 0 1 1 1 1 Bacterial pre-peptidase C-terminal domain Rhomboid PF01694.22 GAX18737.1 - 2.4e-18 66.6 11.3 2.4e-18 66.6 11.3 2.4 2 1 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 GAX18737.1 - 0.34 11.5 10.3 0.1 13.2 2.3 2.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) STIMATE PF12400.8 GAX18738.1 - 0.056 14.0 2.0 0.42 11.2 1.0 2.7 3 0 0 3 3 3 0 STIMATE family Cir_N PF10197.9 GAX18738.1 - 0.96 9.7 7.5 4.5 7.6 6.2 2.7 1 1 1 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF423 PF04241.15 GAX18738.1 - 9.3 6.5 17.0 0.5 10.6 0.1 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF423) TPR_12 PF13424.6 GAX18739.1 - 1e-24 86.6 1.3 3.9e-08 33.5 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18739.1 - 1.3e-15 56.6 2.0 0.0002 21.1 0.2 4.6 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18739.1 - 1.6e-15 56.2 0.7 0.0015 18.3 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18739.1 - 1.3e-14 53.0 0.1 0.0058 16.7 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18739.1 - 2.2e-11 43.0 8.8 0.0014 18.6 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX18739.1 - 3.5e-11 42.3 0.0 0.0019 18.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18739.1 - 1.8e-06 28.3 0.1 0.96 10.4 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 GAX18739.1 - 7.1e-06 25.8 0.5 0.054 13.2 0.4 2.6 1 1 1 2 2 2 2 26S proteasome subunit RPN7 TPR_MalT PF17874.1 GAX18739.1 - 1.2e-05 24.9 0.1 2.3e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 MalT-like TPR region SPO22 PF08631.10 GAX18739.1 - 6.1e-05 22.6 0.5 0.25 10.8 0.1 2.3 1 1 1 2 2 2 2 Meiosis protein SPO22/ZIP4 like TPR_17 PF13431.6 GAX18739.1 - 0.00038 20.7 0.2 2.1 8.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX18739.1 - 0.00058 20.0 0.0 1.5 9.1 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 GAX18739.1 - 0.0006 19.3 2.8 0.0032 17.0 1.4 2.2 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 GAX18739.1 - 0.0011 19.5 0.7 5.7 7.5 0.0 3.6 2 1 1 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.9 GAX18739.1 - 0.0053 16.5 2.5 0.011 15.5 0.9 2.2 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.20 GAX18739.1 - 0.014 15.6 0.1 18 5.8 0.1 3.5 3 0 0 3 3 3 0 PPR repeat DUF627 PF04781.12 GAX18739.1 - 0.015 15.3 1.8 0.027 14.5 0.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF627) DUF4810 PF16068.5 GAX18739.1 - 0.018 15.6 1.7 4.3 8.0 0.0 3.6 3 1 1 4 4 3 0 Domain of unknown function (DUF4810) TPR_6 PF13174.6 GAX18739.1 - 0.019 15.6 5.1 3.2 8.6 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18739.1 - 0.06 14.0 0.0 28 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PAS_9 PF13426.7 GAX18740.1 - 2.9e-16 59.6 0.0 6.6e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 GAX18740.1 - 1.8e-06 27.9 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold bZIP_2 PF07716.15 GAX18740.1 - 2.5e-06 27.5 8.9 5e-06 26.5 8.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX18740.1 - 9.7e-05 22.4 6.7 9.7e-05 22.4 6.7 1.5 1 1 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 GAX18740.1 - 0.00022 21.5 0.0 0.00043 20.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold CASP_C PF08172.12 GAX18740.1 - 0.1 11.9 2.1 0.14 11.5 2.1 1.2 1 0 0 1 1 1 0 CASP C terminal Chloroa_b-bind PF00504.21 GAX18741.1 - 6.4e-23 82.0 0.1 8.9e-23 81.6 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HMG_box PF00505.19 GAX18746.1 - 2.1e-11 44.1 2.4 2.1e-11 44.1 2.4 2.7 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX18746.1 - 3.3e-11 43.6 2.0 3.3e-11 43.6 2.0 2.0 2 1 0 2 2 2 1 HMG-box domain Fe_hyd_lg_C PF02906.14 GAX18747.1 - 7.9e-43 146.9 0.0 1.4e-42 146.1 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain RHH_4 PF13467.6 GAX18747.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain Retrotrans_gag PF03732.17 GAX18747.1 - 0.24 11.7 3.3 0.21 11.9 0.9 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein TPR_2 PF07719.17 GAX18748.1 - 1.2e-09 37.6 11.1 5.8e-05 22.9 0.8 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18748.1 - 1.6e-07 30.8 7.8 5.8e-05 22.7 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18748.1 - 4.2e-05 23.1 8.0 0.022 14.4 0.6 2.8 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 GAX18748.1 - 0.00027 20.8 4.3 0.72 10.0 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18748.1 - 0.00035 20.5 12.2 0.012 15.7 0.5 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX18748.1 - 0.0046 17.2 8.9 1.1 9.6 2.6 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18748.1 - 0.037 14.9 1.5 30 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX18748.1 - 0.15 12.8 3.8 3 8.7 0.7 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4407 PF14362.6 GAX18748.1 - 9.5 5.5 21.0 1.3 8.3 14.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 GAX18749.1 - 1.4e-37 129.1 0.6 1.9e-37 128.6 0.6 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like T3SS_basalb_I PF17001.5 GAX18749.1 - 2.7 8.7 7.3 2.8 8.6 4.9 2.2 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI RVT_2 PF07727.14 GAX18752.1 - 9.3e-31 107.3 0.3 1.8e-30 106.4 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRAM PF01938.20 GAX18754.1 - 0.046 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 TRAM domain DUF4379 PF14311.6 GAX18754.1 - 0.16 12.3 0.1 4.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Probable Zinc-ribbon domain YqzL PF14006.6 GAX18754.1 - 0.25 11.8 1.8 7.1 7.1 0.3 2.4 2 0 0 2 2 2 0 YqzL-like protein RVT_2 PF07727.14 GAX18755.1 - 5.8e-30 104.7 1.7 1.9e-24 86.7 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX18755.1 - 1.4e-08 34.9 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 GAX18755.1 - 0.017 15.0 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 GAG-pre-integrase domain Lyx_isomer PF07385.12 GAX18756.1 - 0.058 12.7 0.2 0.094 12.0 0.2 1.3 1 0 0 1 1 1 0 D-lyxose isomerase Cyclin_C_2 PF16899.5 GAX18757.1 - 1e-12 48.4 2.4 4.2e-09 36.7 0.1 2.8 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 GAX18757.1 - 1.2e-08 34.8 0.1 3.7e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain ShK PF01549.24 GAX18758.1 - 5.8e-14 52.3 23.6 1.4e-07 31.9 7.1 2.3 2 0 0 2 2 2 2 ShK domain-like Paramecium_SA PF01508.16 GAX18758.1 - 1 9.9 13.1 1.2 9.6 2.3 2.3 2 0 0 2 2 2 0 Paramecium surface antigen domain RCC1 PF00415.18 GAX18759.1 - 1.3e-39 134.6 18.6 3.9e-11 43.4 0.0 7.9 7 2 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX18759.1 - 2.7e-32 109.9 15.0 1.9e-07 30.7 0.0 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 GAX18759.1 - 0.15 12.3 5.0 3.5 7.9 0.6 3.8 3 3 0 3 3 3 0 Putative heavy-metal chelation Mpv17_PMP22 PF04117.12 GAX18760.1 - 1.2e-14 54.3 10.8 3.1e-14 52.9 10.8 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family TetR_C_30 PF17939.1 GAX18760.1 - 0.0016 18.7 0.1 0.0032 17.7 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Mpv17_PMP22 PF04117.12 GAX18761.1 - 2.2e-17 63.0 1.5 4e-17 62.2 1.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribonuc_red_sm PF00268.21 GAX18762.1 - 6.4e-119 396.5 0.1 7.7e-119 396.3 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1978 PF09321.10 GAX18762.1 - 0.14 11.4 0.7 3.9 6.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Zn_ribbon_SprT PF17283.2 GAX18763.1 - 0.031 14.2 3.1 4.3 7.3 0.0 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Keratin_2_head PF16208.5 GAX18763.1 - 0.043 14.0 0.2 0.58 10.3 0.0 2.5 2 0 0 2 2 2 0 Keratin type II head Sorting_nexin PF03700.13 GAX18763.1 - 0.1 13.1 3.3 0.32 11.6 3.3 1.9 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain Rsm1 PF08600.10 GAX18763.1 - 0.13 12.4 0.3 0.82 9.9 0.0 2.4 2 1 0 2 2 2 0 Rsm1-like zf-CHY PF05495.12 GAX18763.1 - 0.17 12.4 6.3 0.23 12.0 0.4 3.1 3 0 0 3 3 3 0 CHY zinc finger Defensin_beta_2 PF13841.6 GAX18764.1 - 0.18 12.3 0.1 0.36 11.4 0.1 1.5 1 0 0 1 1 1 0 Beta defensin YqfQ PF14181.6 GAX18764.1 - 3.8 7.7 7.3 7.5 6.7 7.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein UPF0047 PF01894.17 GAX18765.1 - 5.1e-36 123.3 0.0 7.6e-36 122.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RHD3 PF05879.12 GAX18766.1 - 0.0011 17.3 8.9 0.0014 16.9 8.9 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) ASD1 PF08688.10 GAX18766.1 - 0.87 10.0 6.2 0.33 11.3 0.3 2.5 1 1 1 2 2 2 0 Apx/Shroom domain ASD1 YbjQ_1 PF01906.17 GAX18766.1 - 1.4 9.6 4.3 4.7 7.9 0.1 2.7 3 0 0 3 3 3 0 Putative heavy-metal-binding CobT PF06213.12 GAX18767.1 - 0.045 13.1 6.7 0.17 11.2 6.7 2.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IBR PF01485.21 GAX18768.1 - 2.8e-09 37.0 20.7 5.6e-07 29.7 0.7 5.2 4 2 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GAX18768.1 - 5.8e-08 32.6 6.9 5.8e-08 32.6 6.9 5.3 5 1 0 5 5 5 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX18768.1 - 2.4e-07 30.5 3.4 2.4e-07 30.5 3.4 5.8 4 2 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX18768.1 - 9.7e-07 29.0 5.2 9.7e-07 29.0 5.2 6.1 4 1 2 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX18768.1 - 3.8e-05 23.4 1.1 3.8e-05 23.4 1.1 6.2 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX18768.1 - 0.0004 20.3 4.0 0.0004 20.3 4.0 5.5 4 1 1 5 5 5 1 zinc-RING finger domain zf-ribbon_3 PF13248.6 GAX18768.1 - 0.074 12.5 0.2 0.074 12.5 0.2 7.9 7 1 0 7 7 7 0 zinc-ribbon domain Prominin PF05478.11 GAX18768.1 - 0.12 10.3 6.4 0.17 9.8 6.4 1.1 1 0 0 1 1 1 0 Prominin Corona_S2 PF01601.16 GAX18768.1 - 0.6 8.5 5.2 0.88 8.0 5.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ecm29 PF13001.7 GAX18769.1 - 3.3e-28 98.6 3.8 4.1e-24 85.1 0.7 3.7 3 1 0 3 3 3 2 Proteasome stabiliser HEAT PF02985.22 GAX18769.1 - 0.032 14.5 31.0 0.9 10.0 1.3 10.5 11 0 0 11 11 11 0 HEAT repeat SLBB PF10531.9 GAX18769.1 - 0.21 11.5 0.0 0.66 9.9 0.0 1.8 1 0 0 1 1 1 0 SLBB domain Lipase_GDSL_2 PF13472.6 GAX18771.1 - 6.5e-06 26.7 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family LCIB_C_CA PF18599.1 GAX18772.1 - 6.5e-70 234.9 0.0 7.7e-70 234.6 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SMC_Nse1 PF07574.13 GAX18773.1 - 5.8e-11 42.6 0.3 4e-08 33.4 0.3 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex SMC_ScpB PF04079.16 GAX18773.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB PDDEXK_1 PF12705.7 GAX18775.1 - 3.8e-24 86.0 1.8 5.2e-24 85.6 1.8 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Dna2 PF08696.11 GAX18775.1 - 2.2e-05 24.4 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 DUF2800 PF10926.8 GAX18775.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2800) Phage_BR0599 PF09356.10 GAX18775.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage conserved hypothetical protein BR0599 zf-RanBP PF00641.18 GAX18776.1 - 0.012 14.9 1.4 0.012 14.9 1.4 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-C3HC PF07967.13 GAX18776.1 - 0.098 12.7 3.2 0.48 10.5 0.1 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like zf-Sec23_Sec24 PF04810.15 GAX18776.1 - 0.47 10.6 5.3 12 6.0 0.1 3.5 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger NMO PF03060.15 GAX18777.1 - 1.1e-11 44.7 0.1 2.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase AMP-binding PF00501.28 GAX18779.1 - 1e-92 311.0 0.0 1.4e-92 310.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RNA_pol_Rpb5_C PF01191.19 GAX18779.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain EFG_IV PF03764.18 GAX18780.1 - 6.2e-31 106.7 0.0 3.9e-30 104.1 0.0 2.2 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.24 GAX18780.1 - 1.2e-21 76.5 0.0 2.6e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 GAX18780.1 - 9.6e-21 74.2 0.6 1.9e-20 73.2 0.6 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAX18780.1 - 3.2e-15 56.3 0.1 4.4e-14 52.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAX18780.1 - 6.9e-14 51.7 0.1 1.9e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II RF3_C PF16658.5 GAX18780.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Ank_2 PF12796.7 GAX18781.1 - 3e-12 46.9 0.0 0.00032 21.2 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX18781.1 - 2.9e-07 30.9 0.3 0.43 11.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX18781.1 - 1.6e-06 28.3 1.1 0.16 12.3 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX18781.1 - 2.6e-06 27.3 4.7 3.1 8.7 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 GAX18781.1 - 3.1e-05 24.2 7.4 2 9.0 0.1 6.1 7 0 0 7 7 7 2 Ankyrin repeat SCAB_CC PF16712.5 GAX18781.1 - 0.053 13.4 1.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Ras PF00071.22 GAX18782.1 - 1.5e-11 44.2 0.1 1.4e-10 41.0 0.1 2.2 1 1 0 1 1 1 1 Ras family EF_assoc_2 PF08356.12 GAX18782.1 - 1.3e-09 37.9 0.0 3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF-hand_1 PF00036.32 GAX18782.1 - 6.4e-08 31.6 1.7 0.0028 17.1 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX18782.1 - 1.1e-07 31.2 2.2 0.016 15.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAX18782.1 - 1.2e-07 32.0 2.7 1.9e-06 28.2 0.9 2.9 2 1 1 3 3 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX18782.1 - 3.2e-07 29.5 5.5 0.00099 18.5 0.2 3.1 3 0 0 3 3 3 2 EF hand Roc PF08477.13 GAX18782.1 - 8.2e-06 26.0 0.0 0.092 13.0 0.0 3.1 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_8 PF13833.6 GAX18782.1 - 0.0026 17.6 0.5 0.89 9.4 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair Arf PF00025.21 GAX18782.1 - 0.0028 17.1 0.1 0.2 11.1 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX18782.1 - 0.016 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX18782.1 - 0.028 14.3 0.1 0.84 9.5 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase EF-hand_10 PF14788.6 GAX18782.1 - 0.12 12.2 0.3 30 4.6 0.0 3.0 3 0 0 3 3 3 0 EF hand MTBP_C PF14920.6 GAX18783.1 - 0.087 12.6 2.7 0.15 11.8 2.7 1.3 1 0 0 1 1 1 0 MDM2-binding Peptidase_C14 PF00656.22 GAX18784.1 - 2.6e-43 148.8 0.2 1.9e-36 126.3 0.0 2.1 2 0 0 2 2 2 2 Caspase domain Cytomega_UL84 PF06284.11 GAX18784.1 - 0.0013 17.3 0.2 0.0022 16.6 0.2 1.2 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein F-protein PF00469.20 GAX18784.1 - 0.045 13.3 0.4 0.079 12.5 0.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef WD40 PF00400.32 GAX18785.1 - 0.0015 19.3 7.0 0.59 11.1 0.1 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Peptidase_S8 PF00082.22 GAX18787.1 - 1.1e-40 139.8 4.1 4.3e-40 137.8 4.1 1.7 1 1 0 1 1 1 1 Subtilase family Peptidase_M43 PF05572.13 GAX18788.1 - 2.5e-16 59.9 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX18788.1 - 0.0003 21.0 0.0 0.00063 19.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX18788.1 - 0.0014 18.3 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX18788.1 - 0.026 15.0 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX18788.1 - 0.043 13.7 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 GAX18788.1 - 0.15 11.0 1.1 0.25 10.2 1.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Kinesin PF00225.23 GAX18789.1 - 2.3e-89 299.6 0.0 4.7e-89 298.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX18789.1 - 3.4e-20 72.5 0.0 2.7e-19 69.6 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding JIP_LZII PF16471.5 GAX18789.1 - 0.00048 20.2 5.4 0.00048 20.2 5.4 4.4 4 0 0 4 4 4 1 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 GAX18789.1 - 0.0016 18.5 5.5 0.0016 18.5 5.5 4.9 3 2 1 4 4 4 2 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 GAX18789.1 - 0.0051 16.5 9.1 0.0051 16.5 9.1 4.2 3 2 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 GAX18789.1 - 0.041 13.3 35.2 0.042 13.3 16.7 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 YabA PF06156.13 GAX18789.1 - 0.045 14.4 24.2 0.19 12.4 4.6 4.7 3 1 1 4 4 4 0 Initiation control protein YabA YlqD PF11068.8 GAX18789.1 - 0.18 12.2 23.9 0.16 12.3 6.5 4.0 4 0 0 4 4 4 0 YlqD protein PRKG1_interact PF15898.5 GAX18789.1 - 2 9.3 37.9 0.3 12.0 6.5 4.8 4 0 0 4 4 4 0 cGMP-dependent protein kinase interacting domain PP2C PF00481.21 GAX18790.1 - 1.2e-35 123.4 0.6 3.4e-20 72.8 0.0 2.8 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAX18790.1 - 0.0004 20.1 0.0 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX18790.1 - 0.0009 19.2 0.0 0.0049 16.8 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) tRNA_synthFbeta PF17759.1 GAX18791.1 - 1.3e-39 135.8 0.0 1.9e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 GAX18791.1 - 1e-35 121.8 0.2 1.4e-33 115.0 0.0 2.7 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 GAX18791.1 - 3e-22 79.1 0.0 5.5e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 GAX18791.1 - 7.4e-16 58.2 0.0 4.1e-14 52.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetase B5 domain Blt1 PF12754.7 GAX18792.1 - 0.026 14.8 4.2 0.029 14.7 0.2 2.6 2 1 0 2 2 2 0 Blt1 N-terminal domain Mrr_N PF14338.6 GAX18792.1 - 0.093 12.9 1.2 0.21 11.7 0.4 2.0 2 0 0 2 2 2 0 Mrr N-terminal domain FbpA PF05833.11 GAX18793.1 - 2e-13 50.0 2.4 2e-13 50.0 2.4 2.0 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_2 PF18297.1 GAX18793.1 - 7.4e-07 29.3 0.0 1.9e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_1 PF05670.13 GAX18793.1 - 1.4e-06 28.9 0.0 5.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain PLAC8 PF04749.17 GAX18795.1 - 8.8e-07 29.9 9.7 1.7e-06 28.9 9.7 1.5 1 1 0 1 1 1 1 PLAC8 family RNA_pol_Rpb1_5 PF04998.17 GAX18796.1 - 1.6e-93 313.0 0.0 2.6e-93 312.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAX18796.1 - 4.4e-73 245.0 0.0 1e-72 243.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 GAX18796.1 - 5e-73 246.2 0.0 1e-72 245.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_6 PF04992.14 GAX18796.1 - 3.8e-58 196.5 0.1 6.7e-58 195.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 GAX18796.1 - 4.2e-42 143.4 0.9 1.1e-41 141.9 0.9 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 GAX18796.1 - 7.9e-42 142.8 0.1 2.3e-41 141.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAX18796.1 - 7.2e-36 122.4 0.2 2e-35 121.0 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 GAX18796.1 - 4.4e-12 45.7 194.6 0.019 15.3 14.0 12.1 11 1 0 11 11 11 7 RNA polymerase Rpb1 C-terminal repeat DUF2524 PF10732.9 GAX18796.1 - 0.086 13.2 0.2 0.4 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) FliJ PF02050.16 GAX18796.1 - 0.13 12.5 0.5 0.27 11.5 0.5 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein GP38 PF05268.11 GAX18796.1 - 5.4 6.6 6.8 9.4 5.8 6.8 1.3 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 FG-GAP_2 PF14312.6 GAX18797.1 - 5e-54 180.3 14.9 2.7e-13 49.9 6.3 7.1 7 0 0 7 7 7 6 FG-GAP repeat HisK_sensor PF18698.1 GAX18797.1 - 0.0012 19.3 0.2 1.4 9.3 0.0 4.1 4 0 0 4 4 4 1 Histidine kinase sensor domain Kelch_3 PF13415.6 GAX18797.1 - 0.0035 17.6 0.1 1.9 8.9 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Imm31 PF15591.6 GAX18797.1 - 0.36 10.7 3.1 25 4.8 0.1 3.9 3 1 0 4 4 4 0 Immunity protein 31 FG-GAP PF01839.23 GAX18797.1 - 1.7 8.9 20.3 7.1 6.9 0.2 5.5 6 0 0 6 6 6 0 FG-GAP repeat ABC_tran PF00005.27 GAX18798.1 - 3.7e-49 166.8 0.7 4.7e-26 91.9 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAX18798.1 - 1.3e-14 54.8 4.0 3.1e-05 23.9 0.0 4.5 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 GAX18798.1 - 3.1e-12 46.3 2.7 3.1e-12 46.3 2.7 2.9 2 1 1 3 3 2 1 ABC transporter ABC_tran_CTD PF16326.5 GAX18798.1 - 9.3e-09 35.4 11.1 4.1e-08 33.4 11.1 2.1 1 0 0 1 1 1 1 ABC transporter C-terminal domain AAA_15 PF13175.6 GAX18798.1 - 2.2e-07 30.9 1.4 0.058 13.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 GAX18798.1 - 5.9e-07 30.2 6.9 0.081 13.4 0.0 3.7 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 GAX18798.1 - 2.1e-06 27.8 0.5 0.012 15.6 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX18798.1 - 8.4e-06 25.4 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX18798.1 - 9.7e-06 25.6 2.2 0.052 13.5 0.1 2.7 3 0 0 3 3 2 2 RsgA GTPase TsaE PF02367.17 GAX18798.1 - 1.2e-05 25.3 0.1 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 GAX18798.1 - 4.7e-05 23.8 1.5 0.29 11.6 0.0 3.5 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 GAX18798.1 - 6.8e-05 22.4 8.1 0.37 10.2 0.0 4.4 4 1 0 5 5 4 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 GAX18798.1 - 6.9e-05 23.4 1.7 0.14 12.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 GAX18798.1 - 7e-05 23.0 0.5 0.13 12.5 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 GAX18798.1 - 9.2e-05 22.4 0.9 0.29 11.1 0.2 2.7 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 GAX18798.1 - 0.00015 21.6 7.0 0.2 11.3 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 GAX18798.1 - 0.00038 20.7 2.3 0.17 12.1 0.3 3.6 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAX18798.1 - 0.0004 20.7 0.2 0.98 9.8 0.1 2.6 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 GAX18798.1 - 0.00045 20.2 1.0 0.15 12.1 0.1 3.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 GAX18798.1 - 0.00053 18.8 7.7 0.33 9.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 GAX18798.1 - 0.00062 19.7 2.2 4 7.3 0.0 3.9 3 1 0 3 3 3 0 NTPase AAA_33 PF13671.6 GAX18798.1 - 0.0015 18.7 8.0 0.047 13.9 0.5 4.0 4 1 0 4 4 4 1 AAA domain ATP-synt_ab PF00006.25 GAX18798.1 - 0.0019 17.9 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 GAX18798.1 - 0.002 17.8 0.3 0.74 9.4 0.1 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain dNK PF01712.19 GAX18798.1 - 0.0023 17.8 1.4 0.85 9.4 0.2 2.7 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_25 PF13481.6 GAX18798.1 - 0.0025 17.4 7.8 0.26 10.9 0.0 4.3 5 0 0 5 5 4 1 AAA domain AAA_28 PF13521.6 GAX18798.1 - 0.0089 16.3 10.9 0.23 11.7 0.1 3.9 4 0 0 4 4 3 2 AAA domain SbcCD_C PF13558.6 GAX18798.1 - 0.011 15.9 0.1 9.9 6.5 0.0 3.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 GAX18798.1 - 0.011 15.2 0.2 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 GAX18798.1 - 0.012 15.4 0.2 1.1 8.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 GAX18798.1 - 0.02 14.5 1.1 3 7.4 0.2 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 GAX18798.1 - 0.022 13.9 0.1 1.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 GAX18798.1 - 0.025 15.0 4.5 0.26 11.7 0.6 2.9 2 2 0 2 2 2 0 AAA ATPase domain kleA_kleC PF17383.2 GAX18798.1 - 0.028 14.7 1.9 0.12 12.7 1.9 2.1 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A FeoB_N PF02421.18 GAX18798.1 - 0.052 13.1 0.1 12 5.4 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B SOAR PF16533.5 GAX18798.1 - 0.059 13.4 8.7 0.19 11.7 8.7 1.8 1 0 0 1 1 1 0 STIM1 Orai1-activating region RuvB_N PF05496.12 GAX18798.1 - 0.071 12.9 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 GAX18798.1 - 0.098 12.4 1.0 6.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1510 PF07423.11 GAX18798.1 - 0.11 12.7 1.0 5.1 7.3 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) TolA_bind_tri PF16331.5 GAX18798.1 - 0.37 10.9 6.6 2.8 8.1 6.3 2.4 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF4164 PF13747.6 GAX18798.1 - 0.58 10.5 8.1 2.1 8.7 8.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Dynamin_N PF00350.23 GAX18798.1 - 0.85 9.7 6.8 5.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.15 GAX18798.1 - 0.96 9.0 6.4 0.21 11.1 2.4 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Zeta_toxin PF06414.12 GAX18798.1 - 1 8.6 10.2 0.88 8.8 0.0 3.8 4 0 0 4 4 4 0 Zeta toxin MeaB PF03308.16 GAX18798.1 - 1 8.3 7.2 6.2 5.7 0.0 3.2 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TBCC_N PF16752.5 GAX18798.1 - 1.5 9.3 9.6 4.1 7.9 9.6 1.7 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain DivIC PF04977.15 GAX18798.1 - 1.6 8.6 9.4 4.5 7.1 4.8 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF1043 PF06295.12 GAX18798.1 - 1.9 8.5 7.2 0.51 10.3 3.5 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF1043) TMF_DNA_bd PF12329.8 GAX18798.1 - 1.9 8.5 13.5 0.27 11.2 7.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 GAX18798.1 - 2.8 6.4 6.9 4.3 5.8 6.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 GAX18798.1 - 2.9 8.0 11.8 0.24 11.5 7.0 1.8 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus KLRAQ PF10205.9 GAX18798.1 - 2.9 8.2 11.1 11 6.4 11.1 2.0 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.9 GAX18798.1 - 6.1 5.8 15.0 0.15 11.2 8.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 GAX18798.1 - 6.4 6.0 11.6 5.1 6.4 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 GAX18798.1 - 7.6 7.1 9.2 27 5.3 8.8 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 GAX18798.1 - 9.1 6.3 8.8 2.4 8.2 5.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) Sina PF03145.16 GAX18800.1 - 1.4e-05 25.1 1.3 3e-05 24.1 1.3 1.4 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_2 PF13923.6 GAX18800.1 - 1.4e-05 24.8 10.1 4.1e-05 23.3 10.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX18800.1 - 1.6e-05 25.1 10.2 4.4e-05 23.7 10.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAX18800.1 - 2.3e-05 24.2 8.9 4.3e-05 23.3 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 GAX18800.1 - 6.2e-05 23.6 3.8 0.00015 22.4 3.8 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 GAX18800.1 - 0.015 15.1 10.3 0.038 13.9 10.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.12 GAX18800.1 - 0.078 12.7 7.9 0.03 14.0 5.2 1.6 1 1 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_UBOX PF13445.6 GAX18800.1 - 0.11 12.5 8.1 0.035 14.2 3.2 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAX18800.1 - 0.26 11.3 11.0 0.56 10.2 11.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GAX18800.1 - 1.1 9.2 8.2 3.6 7.5 8.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 GAX18800.1 - 1.7 8.5 15.0 0.13 12.1 9.5 2.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-TRAF_2 PF15965.5 GAX18800.1 - 6.7 7.2 12.7 0.05 14.1 3.7 2.0 1 1 1 2 2 2 0 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 GAX18800.1 - 7.6 6.8 18.6 0.34 11.1 12.4 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4611 PF15387.6 GAX18801.1 - 0.5 10.6 11.6 3 8.1 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GAX18801.1 - 0.63 9.3 11.8 0.089 12.1 4.4 2.0 2 0 0 2 2 2 0 NOA36 protein DUF3246 PF11596.8 GAX18801.1 - 0.9 8.9 9.8 1.9 7.9 9.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 GAX18801.1 - 1.5 9.2 18.8 0.94 9.9 8.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 GAX18801.1 - 2 8.8 14.0 9.5 6.7 0.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.12 GAX18801.1 - 2.3 8.2 5.1 6.6 6.7 1.9 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 BUD22 PF09073.10 GAX18801.1 - 2.6 7.3 5.9 3.5 6.9 5.9 1.1 1 0 0 1 1 1 0 BUD22 Glyco_trans_1_4 PF13692.6 GAX18802.1 - 0.00013 22.4 0.0 0.025 15.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX18802.1 - 0.00035 20.2 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 LPD39 PF18858.1 GAX18802.1 - 0.045 13.8 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 Glyco_trans_1_2 PF13524.6 GAX18802.1 - 0.046 14.1 0.1 0.19 12.1 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferases group 1 ShK PF01549.24 GAX18804.1 - 0.014 15.9 5.2 0.014 15.9 5.2 3.9 4 0 0 4 4 4 0 ShK domain-like Pilin_N PF07790.11 GAX18806.1 - 0.08 13.9 0.0 0.19 12.6 0.0 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF3410 PF11890.8 GAX18806.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) HemolysinCabind PF00353.19 GAX18807.1 - 6.9e-13 48.3 78.4 7.5e-07 29.0 12.2 22.8 23 3 2 25 25 25 10 RTX calcium-binding nonapeptide repeat (4 copies) LRR_8 PF13855.6 GAX18808.1 - 0.0062 16.3 5.0 0.0062 16.3 5.0 1.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX18808.1 - 0.012 16.0 1.8 0.03 14.7 1.8 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX18808.1 - 0.02 15.2 1.5 0.02 15.2 1.5 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Glycos_transf_1 PF00534.20 GAX18809.1 - 0.0094 15.5 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX18809.1 - 0.046 14.2 0.0 0.63 10.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Diphthamide_syn PF01866.17 GAX18810.1 - 1.9e-106 355.9 0.0 2.3e-106 355.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein zinc_ribbon_4 PF13717.6 GAX18811.1 - 0.17 11.8 0.8 0.39 10.7 0.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Amidohydro_1 PF01979.20 GAX18812.1 - 1.1e-56 192.6 0.0 1.5e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAX18812.1 - 2.7e-09 37.0 0.0 7.2e-07 29.0 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 GAX18812.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase HSF_DNA-bind PF00447.17 GAX18813.1 - 1.7e-14 54.2 0.1 3.4e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding PD40 PF07676.12 GAX18813.1 - 0.018 15.0 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Pro_isomerase PF00160.21 GAX18814.1 - 0.0016 18.8 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Catalase-rel PF06628.12 GAX18815.1 - 0.018 15.2 1.7 0.83 9.9 0.1 2.6 2 0 0 2 2 2 0 Catalase-related immune-responsive Phostensin_N PF13916.6 GAX18815.1 - 0.06 13.7 0.5 0.11 12.9 0.5 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal TPR_14 PF13428.6 GAX18815.1 - 0.15 12.9 3.3 5 8.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX18815.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HLH PF00010.26 GAX18816.1 - 0.0012 18.7 0.2 0.0031 17.4 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ERM PF00769.19 GAX18816.1 - 0.002 18.0 9.2 0.084 12.7 0.1 2.3 2 0 0 2 2 2 2 Ezrin/radixin/moesin family RRM PF10378.9 GAX18816.1 - 1.4 8.7 7.7 2.4 7.9 2.9 2.9 2 0 0 2 2 2 0 Putative RRM domain UPF0449 PF15136.6 GAX18816.1 - 3.6 8.1 11.0 2.3 8.7 1.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 COMM_domain PF07258.14 GAX18816.1 - 3.7 7.7 5.7 0.87 9.8 0.2 2.6 3 0 0 3 3 3 0 COMM domain Peptidase_M6 PF05547.11 GAX18817.1 - 0.00041 18.8 4.5 0.0013 17.2 4.5 1.9 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 Neocarzinostat PF00960.18 GAX18817.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Neocarzinostatin family PP2C PF00481.21 GAX18819.1 - 4.7e-59 200.1 0.0 4.6e-57 193.6 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX18819.1 - 0.0005 19.8 0.0 0.0012 18.5 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C adh_short PF00106.25 GAX18820.1 - 8.6e-21 74.3 0.0 3.4e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX18820.1 - 1.1e-09 38.2 0.0 3.9e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAX18820.1 - 4.9e-07 29.4 0.0 7.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAX18820.1 - 0.0005 20.0 0.0 0.00069 19.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF5507 PF17612.2 GAX18821.1 - 0.00087 19.0 1.0 7 6.4 0.0 3.4 1 1 3 4 4 4 3 Family of unknown function (DUF5507) VPS11_C PF12451.8 GAX18821.1 - 0.022 15.0 1.6 1.4e+02 2.8 0.0 4.5 4 1 1 5 5 5 0 Vacuolar protein sorting protein 11 C terminal ATP-grasp_6 PF18419.1 GAX18821.1 - 5.6 6.7 11.8 51 3.6 0.2 4.5 2 1 3 5 5 5 0 ATP-grasp-like domain Arena_ncap_C PF17290.2 GAX18821.1 - 5.8 6.2 9.8 6.2 6.1 0.5 3.2 1 1 2 3 3 3 0 Arenavirus nucleocapsid C-terminal domain Conotoxin PF02950.17 GAX18822.1 - 0.25 12.4 0.1 0.65 11.1 0.1 1.8 1 1 0 1 1 1 0 Conotoxin Vpu PF00558.19 GAX18822.1 - 0.51 10.2 2.2 51 3.7 0.0 2.3 2 1 0 2 2 2 0 Vpu protein CobT PF06213.12 GAX18824.1 - 0.44 9.9 15.4 0.58 9.5 15.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CRAL_TRIO PF00650.20 GAX18826.1 - 3.9e-36 124.2 0.0 5.4e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX18826.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain TPR_8 PF13181.6 GAX18827.1 - 2.7e-10 39.6 10.5 0.0012 18.9 1.1 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX18827.1 - 1.3e-09 38.2 15.9 8.6e-05 22.7 1.0 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18827.1 - 1.6e-09 37.1 21.0 0.0014 18.6 1.9 5.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18827.1 - 8.1e-08 31.8 12.7 0.03 14.1 2.7 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18827.1 - 3.5e-05 24.4 11.0 0.68 10.6 0.2 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18827.1 - 8.1e-05 23.1 11.0 0.08 13.8 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18827.1 - 0.00011 22.0 15.4 0.12 12.3 0.2 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 GAX18827.1 - 0.0002 21.4 0.7 2.6 8.1 0.0 4.1 4 0 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_MalT PF17874.1 GAX18827.1 - 0.00022 20.7 10.2 0.076 12.4 0.2 3.2 2 1 0 2 2 2 2 MalT-like TPR region TPR_11 PF13414.6 GAX18827.1 - 0.0015 18.2 13.2 0.76 9.5 3.8 5.2 4 1 0 4 4 4 2 TPR repeat SHNi-TPR PF10516.9 GAX18827.1 - 0.0092 15.4 3.4 0.2 11.2 0.3 2.9 2 0 0 2 2 2 1 SHNi-TPR SNAP PF14938.6 GAX18827.1 - 0.018 14.5 0.6 0.018 14.5 0.6 3.2 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP GP70 PF17429.2 GAX18827.1 - 0.034 14.0 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Gene product 70 TPR_7 PF13176.6 GAX18827.1 - 0.048 13.7 9.0 7.4 6.8 1.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX18827.1 - 0.055 13.6 6.0 0.62 10.3 0.1 3.3 3 1 1 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.9 GAX18827.1 - 0.19 11.4 2.7 16 5.2 0.1 2.9 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 GAX18827.1 - 0.62 10.6 17.3 2.1 8.9 2.9 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX18827.1 - 1.3 9.8 16.8 5.6 7.8 1.4 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GAX18827.1 - 2.5 8.4 6.8 0.25 11.7 0.5 2.5 4 0 0 4 4 3 0 Retrotransposon gag protein TPR_21 PF09976.9 GAX18827.1 - 6.4 6.4 9.5 1.1 9.0 0.1 3.4 4 1 1 5 5 4 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 GAX18828.1 - 1e-05 25.7 13.2 0.16 12.3 0.1 5.4 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18828.1 - 0.00013 21.8 14.5 0.027 14.6 0.3 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAX18828.1 - 0.0003 20.9 0.2 3.3 8.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TOM20_plant PF06552.12 GAX18828.1 - 0.0025 17.6 0.3 0.52 10.0 0.2 2.5 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 Vir_act_alpha_C PF10400.9 GAX18828.1 - 0.0066 17.1 3.0 0.062 14.0 0.1 2.7 2 0 0 2 2 2 1 Virulence activator alpha C-term BTAD PF03704.17 GAX18828.1 - 0.011 16.2 0.1 0.011 16.2 0.1 2.7 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Phenyl_P_gamma PF09662.10 GAX18828.1 - 0.011 15.9 0.1 0.039 14.1 0.1 2.0 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) TPR_1 PF00515.28 GAX18828.1 - 0.014 15.2 10.5 0.69 9.8 0.6 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18828.1 - 0.016 16.0 15.1 16 6.6 0.7 6.7 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX18828.1 - 0.085 13.5 0.4 1.8e+02 3.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18828.1 - 0.55 10.6 10.3 2.7 8.4 0.4 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18828.1 - 0.85 9.6 14.5 27 4.8 0.2 5.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAX18828.1 - 2.6 8.1 10.1 42 4.3 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat YnfE PF17452.2 GAX18828.1 - 5.4 7.4 7.7 11 6.4 2.8 2.6 2 0 0 2 2 2 0 Uncharacterized YnfE-like TPR_12 PF13424.6 GAX18829.1 - 0.00051 20.3 21.1 0.018 15.3 3.5 6.0 4 3 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18829.1 - 0.00079 19.4 3.7 4.3 7.8 0.1 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 GAX18829.1 - 0.0015 19.0 13.1 0.32 11.4 0.2 3.9 4 0 0 4 4 4 2 Bacterial transcriptional activator domain TPR_1 PF00515.28 GAX18829.1 - 0.0025 17.6 9.0 0.069 13.0 0.2 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18829.1 - 0.0039 17.2 20.0 0.01 15.8 0.2 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat Halo_GVPC PF05465.13 GAX18829.1 - 0.0063 16.7 3.7 2 8.8 0.1 3.5 3 0 0 3 3 3 2 Halobacterial gas vesicle protein C (GVPC) repeat Methyltransf_4 PF02390.17 GAX18829.1 - 0.022 14.2 0.4 0.045 13.2 0.1 1.8 2 0 0 2 2 2 0 Putative methyltransferase TPR_7 PF13176.6 GAX18829.1 - 0.067 13.2 6.2 3.6 7.8 0.1 5.1 3 1 1 4 4 4 0 Tetratricopeptide repeat GatB_Yqey PF02637.18 GAX18829.1 - 0.1 12.5 1.4 0.42 10.5 0.6 2.4 3 0 0 3 3 3 0 GatB domain DUF3906 PF13046.6 GAX18829.1 - 0.11 12.6 0.9 11 6.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) TPR_14 PF13428.6 GAX18829.1 - 0.12 13.2 21.8 2.1 9.4 0.4 7.3 6 3 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX18829.1 - 0.17 12.6 8.8 4.1 8.2 0.9 5.3 5 1 0 5 5 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX18829.1 - 0.92 9.0 4.7 0.82 9.2 0.3 3.2 3 0 0 3 3 3 0 SHNi-TPR TPR_16 PF13432.6 GAX18829.1 - 0.97 10.1 16.7 0.88 10.3 0.3 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat Phage_HK97_TLTM PF06120.11 GAX18829.1 - 1.3 8.1 12.2 0.21 10.8 1.5 3.3 3 1 0 3 3 3 0 Tail length tape measure protein TPR_11 PF13414.6 GAX18829.1 - 1.4 8.6 6.1 20 5.0 0.3 4.0 4 0 0 4 4 4 0 TPR repeat TPR_12 PF13424.6 GAX18830.1 - 2.6e-16 59.7 32.4 7.1e-06 26.2 5.4 5.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18830.1 - 1.1e-15 56.6 13.7 0.00082 19.1 1.8 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18830.1 - 2.3e-12 46.0 24.8 0.00084 19.3 1.4 8.4 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18830.1 - 1.6e-09 37.2 21.6 0.00045 20.2 1.4 7.5 7 1 1 8 8 7 2 Tetratricopeptide repeat SNAP PF14938.6 GAX18830.1 - 4.9e-08 32.7 17.0 0.0071 15.8 1.8 3.4 3 1 0 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 GAX18830.1 - 4.6e-07 29.4 14.9 0.064 13.0 1.1 6.5 6 1 0 6 6 6 3 TPR repeat TPR_MalT PF17874.1 GAX18830.1 - 4.7e-07 29.5 28.2 3.5e-05 23.3 0.4 4.0 1 1 3 5 5 5 2 MalT-like TPR region TPR_19 PF14559.6 GAX18830.1 - 1.7e-05 25.2 29.3 0.037 14.6 9.6 6.0 4 2 1 5 5 5 3 Tetratricopeptide repeat DUF3856 PF12968.7 GAX18830.1 - 4.3e-05 23.6 3.5 0.00019 21.5 0.2 3.1 4 0 0 4 4 3 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 GAX18830.1 - 7.7e-05 22.8 13.4 0.59 10.6 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18830.1 - 0.00013 22.5 30.7 0.0039 17.8 0.8 6.1 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX18830.1 - 0.00023 20.9 22.7 0.75 9.7 0.2 7.9 7 1 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX18830.1 - 0.0045 17.7 26.2 0.81 10.7 0.9 7.7 4 3 4 8 8 7 1 Tetratricopeptide repeat DUF4248 PF14053.6 GAX18830.1 - 0.011 15.8 3.8 0.021 14.8 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) TPR_4 PF07721.14 GAX18830.1 - 0.018 15.6 9.7 3.8 8.4 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX18830.1 - 0.087 13.5 32.9 0.3 11.8 2.6 7.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX18830.1 - 0.11 12.6 25.2 0.33 11.1 0.9 7.4 6 2 1 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 GAX18830.1 - 2.2 8.0 6.3 1.1 9.0 0.3 3.1 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_9 PF13371.6 GAX18830.1 - 2.7 8.2 22.5 0.29 11.3 1.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX18831.1 - 8.2e-06 25.6 16.7 0.063 13.4 1.6 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX18831.1 - 4.4e-05 23.1 13.3 0.11 12.4 1.8 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX18831.1 - 0.00014 22.1 18.2 0.28 11.5 1.3 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX18831.1 - 0.021 15.0 2.0 0.021 15.0 2.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat OTU PF02338.19 GAX18831.1 - 0.033 14.7 0.2 0.12 12.9 0.2 1.9 1 0 0 1 1 1 0 OTU-like cysteine protease TPR_19 PF14559.6 GAX18831.1 - 0.05 14.1 5.5 0.18 12.3 1.7 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX18831.1 - 0.26 11.4 2.6 1.5 9.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX18831.1 - 0.34 11.6 11.1 11 6.8 0.1 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat DUF2407_C PF13373.6 GAX18831.1 - 0.55 10.4 1.9 1.3 9.2 0.0 2.5 3 0 0 3 3 3 0 DUF2407 C-terminal domain RPN7 PF10602.9 GAX18831.1 - 1.2 8.8 6.7 2.7 7.7 0.2 3.4 3 1 0 3 3 3 0 26S proteasome subunit RPN7 Uso1_p115_C PF04871.13 GAX18831.1 - 1.9 8.8 9.7 0.49 10.8 4.6 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_11 PF13414.6 GAX18831.1 - 5.3 6.8 6.9 20 5.0 0.1 4.1 4 0 0 4 4 4 0 TPR repeat Cyt-b5 PF00173.28 GAX18832.1 - 6.9e-14 51.8 0.1 2.1e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain CDC27 PF09507.10 GAX18832.1 - 0.16 11.3 26.0 0.26 10.6 26.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Phos_pyr_kin PF08543.12 GAX18834.1 - 7.8e-17 61.5 0.0 1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 GAX18834.1 - 2.7e-06 26.9 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Branch PF02485.21 GAX18835.1 - 0.00088 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Picorna_P3A PF06363.11 GAX18836.1 - 0.08 12.8 0.3 0.11 12.4 0.3 1.2 1 0 0 1 1 1 0 Picornaviridae P3A protein DUF2612 PF11041.8 GAX18838.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) Terpene_synth PF01397.21 GAX18843.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain ArlS_N PF18719.1 GAX18851.1 - 0.08 13.2 0.0 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 ArlS sensor domain ATP_bind_1 PF03029.17 GAX18852.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Serinc PF03348.15 GAX18853.1 - 0.64 8.9 1.1 0.93 8.3 1.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SIR2 PF02146.17 GAX18854.1 - 2.2e-35 122.2 0.1 1.2e-34 119.8 0.1 2.0 1 1 0 1 1 1 1 Sir2 family HscB_4_cys PF18256.1 GAX18854.1 - 2.2 8.1 4.6 6.2 6.7 1.7 2.4 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif MSP PF01716.18 GAX18855.1 - 7.2e-88 293.8 0.2 8.3e-88 293.6 0.2 1.0 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide ATP-synt_S1 PF05827.12 GAX18856.1 - 0.0024 17.7 0.2 0.0083 16.0 0.0 1.9 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) UxaC PF02614.14 GAX18856.1 - 0.029 13.3 0.6 0.034 13.0 0.6 1.1 1 0 0 1 1 1 0 Glucuronate isomerase EMC3_TMCO1 PF01956.16 GAX18856.1 - 0.81 9.4 5.4 0.14 11.9 1.6 1.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PsbQ PF05757.11 GAX18857.1 - 0.0039 17.0 12.5 0.072 12.8 12.5 2.5 1 1 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) TPP_enzyme_C PF02775.21 GAX18857.1 - 0.47 10.2 3.4 0.25 11.1 0.5 2.0 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain LRR_8 PF13855.6 GAX18858.1 - 3.1e-50 167.8 119.9 4.7e-08 32.7 2.6 21.9 19 4 5 24 24 24 18 Leucine rich repeat LRR_4 PF12799.7 GAX18858.1 - 1.8e-39 133.1 111.2 0.00016 22.0 0.1 26.1 22 7 4 27 27 27 15 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX18858.1 - 3.3e-05 24.1 27.7 0.062 13.6 0.6 6.0 5 0 0 5 5 5 3 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GAX18858.1 - 0.00011 22.3 99.5 1.9 9.4 0.1 26.0 30 0 0 30 30 30 2 Leucine Rich Repeat DUF3338 PF11819.8 GAX18858.1 - 0.00012 22.0 2.3 2 8.4 0.0 5.4 6 0 0 6 6 6 1 Domain of unknown function (DUF3338) LRR_6 PF13516.6 GAX18858.1 - 0.12 12.5 69.0 28 5.1 0.0 22.1 27 0 0 27 27 27 0 Leucine Rich repeat INSIG PF07281.12 GAX18859.1 - 0.00036 20.3 0.1 0.00098 18.8 0.1 1.6 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Na_Pi_cotrans PF02690.15 GAX18860.1 - 5.3e-36 123.8 37.4 1.1e-20 74.2 11.0 3.0 2 1 0 2 2 2 2 Na+/Pi-cotransporter DUF953 PF06110.11 GAX18860.1 - 0.06 13.0 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) PDR_assoc PF08370.11 GAX18860.1 - 0.12 12.1 1.0 0.51 10.1 1.0 2.1 1 0 0 1 1 1 0 Plant PDR ABC transporter associated DUF4886 PF16227.5 GAX18861.1 - 2.6e-10 39.9 0.0 5.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4886) DUF4519 PF15012.6 GAX18861.1 - 0.0056 16.8 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF2370 PF10176.9 GAX18861.1 - 0.068 12.8 0.2 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) SurA_N_2 PF13623.6 GAX18861.1 - 0.072 12.9 0.1 0.072 12.9 0.1 2.0 3 0 0 3 3 3 0 SurA N-terminal domain Lipase_GDSL_2 PF13472.6 GAX18861.1 - 0.076 13.4 0.1 0.19 12.1 0.0 1.8 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Tad PF13400.6 GAX18861.1 - 0.09 13.1 1.7 1.1 9.7 0.2 2.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF4448 PF14610.6 GAX18861.1 - 0.099 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Cystatin PF00031.21 GAX18861.1 - 0.19 12.0 0.5 0.35 11.2 0.5 1.4 1 0 0 1 1 1 0 Cystatin domain Copine PF07002.16 GAX18862.1 - 4e-48 163.8 0.0 5.7e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX18862.1 - 2.7e-15 56.5 0.0 2.7e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX18862.1 - 1.6e-06 28.3 0.1 2.9e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus ketoacyl-synt PF00109.26 GAX18862.1 - 0.017 14.7 0.1 0.044 13.4 0.0 1.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain VWA_2 PF13519.6 GAX18863.1 - 0.078 13.6 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Par3_HAL_N_term PF12053.8 GAX18864.1 - 0.2 11.9 1.4 0.31 11.3 0.4 1.8 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins Pyr_redox_2 PF07992.14 GAX18865.1 - 1.3e-30 106.6 0.0 2.1e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX18865.1 - 5.9e-10 39.6 0.0 2.4e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX18865.1 - 0.0011 19.0 0.0 25 4.8 0.0 4.1 3 1 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAX18865.1 - 0.026 14.7 0.1 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAX18865.1 - 0.037 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Sacchrp_dh_NADP PF03435.18 GAX18865.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 GAX18865.1 - 0.068 12.7 0.0 5.8 6.4 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Thiolase_N PF00108.23 GAX18866.1 - 6.9e-81 271.4 0.2 1.3e-80 270.5 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAX18866.1 - 9.6e-47 157.7 1.7 3.1e-46 156.0 0.3 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAX18866.1 - 0.0026 17.4 0.9 0.0046 16.6 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 GAX18866.1 - 0.0045 17.2 0.2 0.057 13.7 0.0 2.6 3 0 0 3 3 3 1 Dodecin ACP_syn_III_C PF08541.10 GAX18866.1 - 0.014 15.6 0.1 0.84 9.9 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Podoplanin PF05808.11 GAX18867.1 - 0.0045 17.1 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 Podoplanin AgrB PF04647.15 GAX18867.1 - 0.11 11.8 0.6 0.17 11.1 0.6 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Podoplanin PF05808.11 GAX18868.1 - 0.031 14.4 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Podoplanin DUF4514 PF14986.6 GAX18868.1 - 0.088 12.8 1.1 0.25 11.4 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) DEC-1_N PF04625.13 GAX18870.1 - 0.017 14.2 3.2 0.026 13.6 3.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Cation_ATPase PF13246.6 GAX18871.1 - 9.6e-06 25.6 0.0 6.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAX18871.1 - 0.00052 20.4 0.0 1.5 9.1 0.0 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAX18872.1 - 2.9e-21 75.8 1.2 1.4e-20 73.5 0.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 GAX18872.1 - 1.3e-06 28.0 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Glucosamine_iso PF01182.20 GAX18874.1 - 3.8e-34 118.5 0.0 4.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 5_nucleotid_C PF02872.18 GAX18875.1 - 1.2e-29 103.6 0.1 2e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 GAX18875.1 - 1.8e-09 38.4 0.0 3.2e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TALPID3 PF15324.6 GAX18875.1 - 6.4 4.3 7.5 9.3 3.8 7.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target 4HBT_2 PF13279.6 GAX18876.1 - 4.8e-13 49.7 0.0 6.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAX18876.1 - 0.00062 20.1 0.1 0.0016 18.7 0.1 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 GAX18876.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-ACP thioesterase Glyoxalase_3 PF13468.6 GAX18878.1 - 1.4e-27 96.9 0.0 1.9e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 GAX18878.1 - 0.00015 22.0 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AA_kinase PF00696.28 GAX18879.1 - 7.2e-13 48.7 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 GAX18879.1 - 5.7e-05 23.3 0.1 0.00013 22.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX18879.1 - 0.00017 21.5 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX18879.1 - 0.00047 20.5 0.2 0.0011 19.3 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4585 PF15232.6 GAX18880.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Proteasome PF00227.26 GAX18881.1 - 3e-32 111.6 0.0 4.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit NifU PF01106.17 GAX18882.1 - 0.03 14.5 0.1 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 NifU-like domain Aa_trans PF01490.18 GAX18883.1 - 3.5e-62 210.4 17.6 5.4e-62 209.8 17.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 GAX18883.1 - 1.2 9.6 13.4 28 5.3 3.0 4.6 3 2 1 4 4 4 0 Domain of unknown function (DUF202) DUF916 PF06030.12 GAX18884.1 - 0.049 13.7 3.1 0.22 11.6 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) Mito_carr PF00153.27 GAX18886.1 - 2e-50 168.7 1.8 7.1e-18 64.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M61 PF05299.12 GAX18886.1 - 0.027 14.9 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 M61 glycyl aminopeptidase Romo1 PF10247.9 GAX18886.1 - 0.062 13.7 1.0 1.8 9.0 0.1 2.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Cnd1 PF12717.7 GAX18887.1 - 1.3e-50 171.6 6.1 8.8e-46 155.9 0.3 4.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX18887.1 - 7.3e-05 22.7 3.1 10 6.7 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 GAX18887.1 - 0.00064 20.2 0.2 1.6 9.3 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 GAX18887.1 - 0.048 13.8 4.5 3.9 7.7 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 GRIP PF01465.20 GAX18887.1 - 0.066 13.1 0.2 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 GRIP domain Guanylate_cyc PF00211.20 GAX18888.1 - 1.6e-08 34.4 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain hnRNP_Q_AcD PF18360.1 GAX18889.1 - 4.7e-32 109.8 0.0 3e-16 59.1 0.0 3.3 3 0 0 3 3 3 3 Heterogeneous nuclear ribonucleoprotein Q acidic domain WD40 PF00400.32 GAX18890.1 - 1.1e-18 67.2 17.6 9e-05 23.2 0.1 7.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Hira PF07569.11 GAX18890.1 - 2.8e-13 50.1 0.0 1.6e-12 47.6 0.0 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 GAX18890.1 - 1.9e-10 40.9 0.1 0.08 13.3 0.0 6.9 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain DHFR_2 PF06442.11 GAX18890.1 - 0.015 15.1 0.0 0.059 13.2 0.0 2.0 1 0 0 1 1 1 0 R67 dihydrofolate reductase DUF3403 PF11883.8 GAX18890.1 - 0.31 11.2 2.1 1.5 9.0 2.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) Thioredoxin PF00085.20 GAX18891.1 - 6.7e-24 83.9 0.0 1.1e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin SAP PF02037.27 GAX18891.1 - 5.5e-06 26.0 0.7 0.05 13.4 0.0 3.8 4 0 0 4 4 4 2 SAP domain Thioredoxin_2 PF13098.6 GAX18891.1 - 1.2e-05 25.7 1.0 0.00011 22.6 0.1 2.6 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX18891.1 - 0.00015 21.9 0.1 0.00053 20.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like TraF PF13728.6 GAX18891.1 - 0.00039 20.3 0.1 0.00079 19.3 0.1 1.5 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 GAX18891.1 - 0.0014 18.9 0.0 0.098 13.0 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAX18891.1 - 0.0097 15.9 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 GAX18891.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 GAX18891.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 GAX18891.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 GAX18891.1 - 0.046 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family RNA_pol_Rpb2_7 PF04560.20 GAX18891.1 - 0.16 12.4 0.1 0.51 10.8 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 Aa_trans PF01490.18 GAX18892.1 - 2.2e-08 33.3 4.0 2.2e-08 33.3 4.0 3.2 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 GAX18892.1 - 0.07 13.1 2.4 0.088 12.8 1.0 1.9 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Ank_4 PF13637.6 GAX18893.1 - 1.1e-05 25.8 0.3 0.018 15.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX18893.1 - 0.00019 21.7 0.4 0.0011 19.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX18893.1 - 0.00093 19.7 0.0 0.0025 18.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX18893.1 - 0.009 16.5 0.1 6.7 7.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat TFIIA PF03153.13 GAX18893.1 - 7 6.5 14.5 13 5.6 14.5 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rad52_Rad22 PF04098.15 GAX18894.1 - 6.5e-33 113.8 0.0 1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein SOG2 PF10428.9 GAX18894.1 - 0.44 9.7 8.0 0.55 9.4 8.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MADF_DNA_bdg PF10545.9 GAX18895.1 - 0.41 11.0 1.8 0.6 10.5 0.2 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MSC PF09402.10 GAX18895.1 - 2.5 7.5 9.4 0.48 9.8 1.5 2.3 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Pyr_redox_2 PF07992.14 GAX18896.1 - 5.2e-52 176.9 3.4 6.9e-52 176.5 3.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX18896.1 - 1.8e-28 99.0 0.4 1e-27 96.5 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX18896.1 - 4.5e-13 49.6 1.7 1.1e-12 48.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX18896.1 - 2e-05 23.9 7.5 5.2e-05 22.5 1.8 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAX18896.1 - 4.2e-05 22.8 4.8 0.04 13.0 1.5 2.7 2 1 1 3 3 3 2 FAD binding domain 3HCDH_N PF02737.18 GAX18896.1 - 0.00017 21.5 1.1 0.28 11.0 0.0 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAX18896.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 GAX18896.1 - 0.11 11.9 2.2 0.19 11.0 2.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX18896.1 - 0.24 11.6 6.4 32 4.9 4.5 3.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain zf-RING_6 PF14835.6 GAX18898.1 - 0.0043 16.9 8.2 0.0091 15.9 8.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 GAX18898.1 - 0.0056 16.6 17.5 0.0099 15.8 17.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF1272 PF06906.11 GAX18898.1 - 0.011 15.8 14.0 0.024 14.7 14.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) ATG16 PF08614.11 GAX18898.1 - 0.088 13.0 1.0 0.15 12.3 1.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-RING_2 PF13639.6 GAX18898.1 - 0.38 11.1 16.8 0.7 10.3 16.2 1.8 2 0 0 2 2 2 0 Ring finger domain Rtf2 PF04641.12 GAX18898.1 - 0.99 8.7 3.9 1.7 7.9 3.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 GAX18898.1 - 1 9.3 16.1 0.22 11.4 12.7 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF5428 PF17493.2 GAX18901.1 - 0.1 13.0 0.5 0.1 13.0 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5428) Hamartin PF04388.12 GAX18902.1 - 5.5 5.5 30.6 6.7 5.3 30.6 1.1 1 0 0 1 1 1 0 Hamartin protein CBM_6 PF03422.15 GAX18903.1 - 7.7e-75 249.2 13.1 4e-23 82.1 0.0 5.4 5 0 0 5 5 5 5 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX18903.1 - 8.2e-40 135.4 6.7 4.7e-08 33.2 0.0 5.4 5 0 0 5 5 5 5 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX18903.1 - 1.6e-15 57.5 10.6 0.0013 18.9 0.1 5.7 5 0 0 5 5 5 5 Carbohydrate binding module (family 35) Gly_acyl_tr_C PF08444.10 GAX18903.1 - 0.055 13.7 0.7 34 4.8 0.1 3.9 4 0 0 4 4 4 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Bac_rhamnosid_C PF17390.2 GAX18903.1 - 0.12 12.2 0.1 5.6 6.8 0.1 3.6 3 1 1 4 4 4 0 Bacterial alpha-L-rhamnosidase C-terminal domain Acyltransferase PF01553.21 GAX18904.1 - 2.1e-12 46.8 0.0 3.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CBM_6 PF03422.15 GAX18905.1 - 9.2e-40 135.8 9.0 6.4e-18 65.2 0.0 4.1 4 0 0 4 4 4 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX18905.1 - 2.5e-20 72.7 2.4 3.1e-08 33.7 0.1 3.9 3 1 1 4 4 4 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX18905.1 - 8.2e-07 29.3 0.5 0.057 13.7 0.0 3.7 3 1 0 3 3 3 3 Carbohydrate binding module (family 35) CBM_6 PF03422.15 GAX18906.1 - 2.3e-38 131.3 1.7 2.9e-14 53.4 0.3 3.1 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX18906.1 - 9.4e-20 70.8 0.7 2.9e-08 33.8 0.1 3.3 3 0 0 3 3 3 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX18906.1 - 2.3e-08 34.3 1.4 0.025 14.8 0.0 3.9 3 1 0 3 3 3 3 Carbohydrate binding module (family 35) Rib PF08428.10 GAX18906.1 - 0.0059 16.6 0.4 5 7.2 0.1 3.3 4 0 0 4 4 4 2 Rib/alpha-like repeat PH_14 PF17787.1 GAX18909.1 - 0.093 12.6 0.1 0.41 10.5 0.0 2.0 3 0 0 3 3 3 0 PH domain TIM PF00121.18 GAX18910.1 - 1.6e-82 276.5 0.0 2.4e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase Gp_dh_C PF02800.20 GAX18910.1 - 1e-68 229.9 0.0 2.9e-68 228.4 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX18910.1 - 6.4e-34 116.3 0.0 1.6e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX18910.1 - 0.013 15.6 0.0 0.049 13.8 0.0 2.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 GAX18910.1 - 0.031 13.6 0.0 0.091 12.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Response_reg PF00072.24 GAX18912.1 - 1.2e-25 89.8 0.6 9.6e-20 70.8 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 GAX18912.1 - 9.3e-07 28.8 0.2 3.1e-06 27.1 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 GAX18912.1 - 3.3e-06 27.6 0.0 1.1e-05 25.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 GAX18912.1 - 0.11 13.2 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 GAF domain HMG_box_2 PF09011.10 GAX18913.1 - 4.8e-08 33.5 5.7 1.2e-07 32.2 5.7 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 GAX18913.1 - 5.6e-08 33.1 10.8 9.1e-06 26.0 10.8 2.7 1 1 0 1 1 1 1 HMG (high mobility group) box DEAD PF00270.29 GAX18915.1 - 1.5e-14 54.1 0.0 5.2e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4471 PF14740.6 GAX18915.1 - 0.002 17.4 1.7 0.002 17.4 1.7 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4471) Helicase_C PF00271.31 GAX18915.1 - 0.057 13.8 0.1 0.46 10.8 0.1 2.6 1 1 0 1 1 1 0 Helicase conserved C-terminal domain RNase_PH PF01138.21 GAX18916.1 - 7.6e-32 110.6 0.1 1.3e-31 109.8 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TAL_FSA PF00923.19 GAX18917.1 - 8.4e-28 97.5 0.0 3.1e-27 95.7 0.0 1.7 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Carb_kinase PF01256.17 GAX18918.1 - 9.2e-44 149.7 0.0 1.3e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase PIP5K PF01504.18 GAX18919.1 - 6.8e-63 212.5 0.0 1.7e-62 211.2 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase RPAP1_C PF08620.10 GAX18919.1 - 0.13 12.4 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 RPAP1-like, C-terminal Kinocilin PF15033.6 GAX18919.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Kinocilin protein Acetyltransf_1 PF00583.25 GAX18920.1 - 1.9e-11 44.2 0.0 2.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX18920.1 - 4.9e-10 39.4 0.0 6.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX18920.1 - 1.3e-08 35.1 0.0 1.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX18920.1 - 5.8e-06 26.2 0.0 9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAX18920.1 - 0.0034 17.5 0.1 0.0062 16.6 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAX18920.1 - 0.03 14.4 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 GAX18920.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 GAX18920.1 - 0.09 12.2 0.5 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Rol_Rep_N PF18106.1 GAX18922.1 - 0.02 15.2 0.1 0.045 14.1 0.1 1.6 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain Luciferase_3H PF10284.9 GAX18922.1 - 0.2 11.9 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Luciferase helical bundle domain CENP-Q PF13094.6 GAX18922.1 - 0.77 9.9 21.3 0.035 14.3 11.0 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit OmpH PF03938.14 GAX18922.1 - 8.6 6.7 18.9 0.41 11.0 5.7 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) UPF0016 PF01169.19 GAX18925.1 - 3e-45 152.4 16.5 6.4e-24 84.1 3.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 EF-hand_5 PF13202.6 GAX18925.1 - 1e-07 31.1 0.2 2e-07 30.2 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GAX18925.1 - 3.2e-06 26.3 0.1 5.7e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX18925.1 - 1.1e-05 24.9 0.2 2.4e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAX18925.1 - 8.9e-05 22.9 0.3 0.00023 21.5 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair OFeT_1 PF16955.5 GAX18925.1 - 0.00025 20.8 0.5 0.00082 19.1 0.6 1.8 1 1 1 2 2 2 1 Ferrous iron uptake permease, iron-lead transporter EF-hand_8 PF13833.6 GAX18925.1 - 0.00092 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair SpoIIM PF01944.17 GAX18925.1 - 0.0012 18.9 0.9 0.0032 17.5 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein M EF-hand_7 PF13499.6 GAX18926.1 - 2.6e-06 27.8 0.2 0.24 11.9 0.0 5.3 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX18926.1 - 2.7e-05 23.7 1.9 0.32 11.0 0.0 6.0 7 0 0 7 7 7 1 EF-hand domain EF-hand_1 PF00036.32 GAX18926.1 - 0.00017 20.9 0.8 0.28 10.8 0.0 4.9 4 0 0 4 4 4 1 EF hand RelA_SpoT PF04607.17 GAX18927.1 - 2.8e-17 63.1 0.0 1.7e-16 60.6 0.0 2.2 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 GAX18927.1 - 0.0008 19.2 0.1 0.0019 18.0 0.1 1.6 1 0 0 1 1 1 1 HD domain Ribosomal_L6 PF00347.23 GAX18928.1 - 7.8e-27 93.8 0.2 1.2e-11 45.2 0.1 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 VIT1 PF01988.19 GAX18929.1 - 2.1e-59 201.0 0.1 2.6e-59 200.7 0.1 1.1 1 0 0 1 1 1 1 VIT family Bromodomain PF00439.25 GAX18931.1 - 1e-14 54.4 0.0 5.2e-14 52.1 0.0 2.3 3 0 0 3 3 3 1 Bromodomain TPR_17 PF13431.6 GAX18932.1 - 0.00055 20.1 0.1 0.61 10.6 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX18932.1 - 0.0041 16.8 0.0 0.045 13.4 0.0 2.5 2 0 0 2 2 2 1 TPR repeat DUF4321 PF14209.6 GAX18932.1 - 0.13 12.2 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4321) PAS_4 PF08448.10 GAX18933.1 - 0.0018 18.5 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 GAX18933.1 - 0.039 14.2 0.0 0.099 12.9 0.0 1.7 2 0 0 2 2 2 0 PAS domain DUF927 PF06048.11 GAX18933.1 - 0.058 13.0 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF927) PAS PF00989.25 GAX18933.1 - 0.078 13.0 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 PAS fold HATPase_c PF02518.26 GAX18934.1 - 7.3e-30 103.8 0.0 1.2e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX18934.1 - 3.3e-24 85.2 0.1 5.4e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX18934.1 - 5.3e-16 58.4 0.0 1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX18934.1 - 0.044 13.6 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FleQ PF06490.11 GAX18934.1 - 0.094 13.1 0.1 2 8.8 0.0 2.6 2 1 0 2 2 2 0 Flagellar regulatory protein FleQ Pkinase PF00069.25 GAX18935.1 - 4.5e-41 141.0 0.0 1.7e-30 106.3 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX18935.1 - 5e-17 62.0 0.0 1.7e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX18935.1 - 0.0019 17.6 0.6 0.67 9.2 0.3 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 GAX18935.1 - 0.015 15.2 0.1 0.18 11.7 0.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family HTH_37 PF13744.6 GAX18935.1 - 0.16 12.0 0.1 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Proteasome PF00227.26 GAX18936.1 - 2e-10 40.5 0.1 1.2e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit VHP PF02209.19 GAX18937.1 - 8.5e-14 51.3 4.4 8.5e-14 51.3 4.4 2.8 3 0 0 3 3 3 1 Villin headpiece domain HEAT_2 PF13646.6 GAX18938.1 - 1.4e-05 25.3 0.2 0.0019 18.5 0.1 3.1 2 1 0 2 2 2 1 HEAT repeats DUF3385 PF11865.8 GAX18938.1 - 0.026 14.5 6.3 0.23 11.3 0.0 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) DUF4253 PF14062.6 GAX18938.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) DICT PF10069.9 GAX18939.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system Importin_rep_6 PF18829.1 GAX18939.1 - 0.27 11.4 1.8 0.53 10.4 1.8 1.4 1 0 0 1 1 1 0 Importin repeat 6 OTU PF02338.19 GAX18940.1 - 7.6e-18 65.2 0.0 1.3e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease SEC-C PF02810.15 GAX18940.1 - 4.4e-08 32.9 5.4 8.9e-08 31.9 5.4 1.5 1 0 0 1 1 1 1 SEC-C motif RRM_1 PF00076.22 GAX18941.1 - 7.2e-78 256.4 0.5 5.5e-21 74.2 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAX18941.1 - 7.4e-32 109.4 0.3 2.9e-30 104.3 0.5 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAX18941.1 - 1.9e-05 24.2 0.0 0.66 9.6 0.0 3.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 GAX18941.1 - 9e-05 22.4 0.0 10 6.2 0.0 3.8 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAX18941.1 - 0.00093 19.3 0.2 16 5.7 0.0 4.0 3 1 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 GAX18941.1 - 0.0029 17.6 0.1 8.2 6.5 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RGP PF03214.13 GAX18941.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide KH_1 PF00013.29 GAX18942.1 - 3.6e-44 148.4 11.0 3.4e-15 55.6 1.9 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAX18942.1 - 2e-11 43.6 9.1 0.00053 19.8 0.1 3.6 4 0 0 4 4 4 3 KH domain WW PF00397.26 GAX18942.1 - 6.6e-10 38.9 2.5 1.6e-09 37.7 2.5 1.7 1 0 0 1 1 1 1 WW domain KH_4 PF13083.6 GAX18942.1 - 3.2e-08 33.3 7.0 0.046 13.6 0.7 3.6 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 GAX18942.1 - 5e-06 26.4 0.1 0.025 14.6 0.0 2.7 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 GAX18942.1 - 0.1 12.7 4.6 5.9 7.0 0.2 3.3 3 0 0 3 3 3 0 NusA-like KH domain PQQ PF01011.21 GAX18942.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat SASP PF00269.20 GAX18942.1 - 0.16 12.0 4.7 5.3 7.1 0.0 3.3 3 0 0 3 3 3 0 Small, acid-soluble spore proteins, alpha/beta type PAP_assoc PF03828.19 GAX18943.1 - 3.5e-12 46.3 0.7 8.2e-12 45.2 0.7 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAX18943.1 - 4.2e-11 43.0 0.1 1.3e-10 41.4 0.1 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAX18943.1 - 8.2e-05 22.6 0.0 0.00022 21.2 0.0 1.7 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Herpes_UL92 PF03048.14 GAX18943.1 - 0.23 11.2 0.1 0.39 10.5 0.1 1.3 1 0 0 1 1 1 0 UL92 family IQ PF00612.27 GAX18944.1 - 4.2e-19 66.5 34.4 0.002 17.8 0.3 7.6 7 0 0 7 7 7 7 IQ calmodulin-binding motif Cytokin_check_N PF10407.9 GAX18944.1 - 0.18 11.8 0.1 0.47 10.5 0.1 1.7 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Gemini_V2 PF01524.17 GAX18944.1 - 0.67 10.2 3.3 1 9.6 0.1 3.0 3 0 0 3 3 3 0 Geminivirus V2 protein 7TMR-HDED PF07697.11 GAX18945.1 - 0.0088 16.2 4.5 0.017 15.2 4.5 1.5 1 0 0 1 1 1 1 7TM-HD extracellular DUF4616 PF15394.6 GAX18945.1 - 0.01 14.9 0.5 0.016 14.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) SPATA24 PF15175.6 GAX18945.1 - 0.021 14.7 10.1 0.056 13.3 10.0 1.8 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4071 PF13281.6 GAX18945.1 - 0.17 10.9 2.0 0.26 10.3 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Tho2 PF11262.8 GAX18945.1 - 0.69 9.1 5.5 1.1 8.4 5.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 GAX18945.1 - 2.2 7.8 7.4 5 6.6 7.4 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_Nu1 PF07471.12 GAX18945.1 - 4.7 6.9 8.3 2.3 8.0 5.8 1.7 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Fez1 PF06818.15 GAX18945.1 - 4.9 7.6 16.5 9.4 6.6 16.5 1.4 1 0 0 1 1 1 0 Fez1 Gastrin PF00918.17 GAX18945.1 - 8.6 7.3 7.9 2.8 8.9 1.6 2.9 2 1 1 3 3 3 0 Gastrin/cholecystokinin family Fea1 PF07692.11 GAX18946.1 - 2.5e-07 30.1 5.9 6.8e-06 25.4 0.8 2.4 2 1 0 2 2 2 2 Low iron-inducible periplasmic protein Vpu PF00558.19 GAX18947.1 - 0.075 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Vpu protein Fea1 PF07692.11 GAX18948.1 - 0.0011 18.1 5.5 0.77 8.7 0.0 2.7 2 1 0 2 2 2 2 Low iron-inducible periplasmic protein PGF-CTERM PF18204.1 GAX18948.1 - 2.1 8.4 5.2 10 6.3 5.2 2.2 1 1 0 1 1 1 0 PGF-CTERM motif C2 PF00168.30 GAX18949.1 - 2.4e-05 24.6 0.0 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 C2 domain PCRF PF03462.18 GAX18950.1 - 6.9e-39 133.7 2.3 8e-39 133.5 0.7 1.9 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAX18950.1 - 3.1e-34 117.4 1.1 3.1e-34 117.4 1.1 2.2 2 0 0 2 2 2 1 RF-1 domain YabA PF06156.13 GAX18950.1 - 5.2 7.8 8.7 1.9 9.1 4.8 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF1515 PF07439.11 GAX18950.1 - 5.2 7.1 5.7 0.8 9.7 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Jnk-SapK_ap_N PF09744.9 GAX18950.1 - 8.8 6.5 13.9 1.4 9.2 6.4 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 HA2 PF04408.23 GAX18951.1 - 1.8e-23 82.9 0.0 3.6e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX18951.1 - 6.9e-18 64.8 0.1 1.8e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX18951.1 - 5e-10 39.7 0.0 9.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX18951.1 - 2.3e-06 27.5 0.0 5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX18951.1 - 3.5e-06 27.3 0.0 8.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX18951.1 - 0.0039 16.9 0.0 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAX18951.1 - 0.0045 17.3 0.1 0.011 16.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 GAX18951.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 GAX18951.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GAX18951.1 - 0.024 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 GAX18951.1 - 0.097 12.0 0.0 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 GAX18951.1 - 0.11 11.9 0.0 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 GAX18951.1 - 0.16 11.9 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Ribosomal_S13 PF00416.22 GAX18952.1 - 1e-47 161.7 0.5 1.1e-47 161.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 GAX18952.1 - 0.099 13.1 0.7 0.17 12.4 0.7 1.3 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 IMS_HHH PF11798.8 GAX18952.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif UVR PF02151.19 GAX18952.1 - 0.12 12.1 1.2 0.21 11.4 1.2 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif MRP-S33 PF08293.11 GAX18953.1 - 3.8e-06 27.0 0.5 5.3e-06 26.6 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 HSF_DNA-bind PF00447.17 GAX18954.1 - 1.8e-19 70.1 0.0 3.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding URO-D PF01208.17 GAX18955.1 - 1.5e-94 317.1 0.0 1.7e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) HSF_DNA-bind PF00447.17 GAX18957.1 - 1.1e-19 70.8 0.0 2.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 GAX18958.1 - 2.8e-20 72.7 0.0 4.3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ovate PF04844.13 GAX18960.1 - 0.11 12.5 0.2 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 Transcriptional repressor, ovate RRM_1 PF00076.22 GAX18961.1 - 9e-07 28.6 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smr PF01713.21 GAX18962.1 - 4e-12 46.3 0.4 1.1e-11 44.9 0.1 2.0 2 0 0 2 2 2 1 Smr domain CsgE PF10627.9 GAX18962.1 - 0.74 10.1 5.7 0.17 12.1 1.6 2.1 2 0 0 2 2 2 0 Curli assembly protein CsgE RTP PF02334.16 GAX18962.1 - 2.6 8.7 6.7 0.36 11.5 1.5 2.2 2 0 0 2 2 2 0 Replication terminator protein DUF2358 PF10184.9 GAX18963.1 - 1.3e-15 57.6 0.0 3.3e-15 56.3 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SOUL PF04832.12 GAX18963.1 - 3.1e-14 53.5 0.1 6.6e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 SOUL heme-binding protein TerB PF05099.13 GAX18964.1 - 0.0084 16.1 1.3 0.014 15.3 1.3 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TerB Thioredoxin PF00085.20 GAX18964.1 - 0.025 14.6 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Phosducin PF02114.16 GAX18964.1 - 0.027 13.4 0.2 0.037 13.0 0.2 1.4 1 1 0 1 1 1 0 Phosducin zf-RING_2 PF13639.6 GAX18965.1 - 5.5e-10 39.4 12.2 8.7e-10 38.8 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAX18965.1 - 9.8e-08 31.7 11.9 1.5e-07 31.1 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX18965.1 - 1.1e-07 32.0 8.3 1.9e-07 31.2 8.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX18965.1 - 4.1e-06 26.5 11.0 7.1e-06 25.8 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX18965.1 - 1.6e-05 24.7 12.0 2.3e-05 24.1 12.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX18965.1 - 8.5e-05 22.3 12.3 0.00015 21.6 12.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAX18965.1 - 0.0019 18.1 14.3 0.0029 17.5 14.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX18965.1 - 0.0029 17.6 12.1 0.0062 16.5 12.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAX18965.1 - 0.015 15.4 5.9 0.015 15.4 5.9 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAX18965.1 - 0.078 13.0 5.0 0.14 12.3 5.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 GAX18965.1 - 0.31 11.2 5.3 0.68 10.1 5.3 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 GAX18965.1 - 0.44 10.3 7.8 0.79 9.5 7.8 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 GAX18965.1 - 0.82 9.6 7.6 1.7 8.6 7.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 GAX18965.1 - 4 7.1 10.1 6.2 6.5 10.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type MTHFR PF02219.17 GAX18966.1 - 1.2e-98 330.0 0.0 2.1e-98 329.2 0.0 1.3 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase DHC_N1 PF08385.12 GAX18966.1 - 0.28 9.8 0.0 1.8 7.1 0.0 1.9 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 F420_oxidored PF03807.17 GAX18967.1 - 2.2e-14 53.8 0.0 4.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAX18967.1 - 8.7e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAX18967.1 - 0.00015 21.9 0.0 0.00023 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase P5CR_dimer PF14748.6 GAX18967.1 - 0.00059 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Shikimate_DH PF01488.20 GAX18967.1 - 0.0026 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 GAX18967.1 - 0.0044 17.5 0.0 0.0063 16.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PDH PF02153.17 GAX18967.1 - 0.0056 15.7 0.1 0.01 14.8 0.0 1.5 2 0 0 2 2 2 1 Prephenate dehydrogenase Rossmann-like PF10727.9 GAX18967.1 - 0.017 15.0 0.1 0.043 13.7 0.1 1.6 1 1 1 2 2 2 0 Rossmann-like domain DUF937 PF06078.11 GAX18967.1 - 0.026 15.1 0.6 0.093 13.3 0.8 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) NAD_binding_3 PF03447.16 GAX18967.1 - 0.074 13.7 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 GAX18967.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_Gly3P_dh_N PF01210.23 GAX18967.1 - 0.11 12.5 0.2 0.22 11.5 0.2 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ank_5 PF13857.6 GAX18968.1 - 3.6e-13 49.4 0.0 9.6e-08 32.2 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX18968.1 - 5.6e-13 49.3 0.0 6.8e-10 39.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX18968.1 - 1.7e-12 47.6 0.8 2.1e-05 24.9 0.1 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX18968.1 - 3.5e-07 30.0 0.0 0.0029 18.0 0.0 4.2 5 1 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 GAX18968.1 - 6.4e-07 29.5 0.0 0.36 11.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat MIF PF01187.18 GAX18969.1 - 9e-22 77.5 0.0 1e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 GAX18969.1 - 0.17 11.9 0.0 17 5.4 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme PGM_PMM_I PF02878.16 GAX18970.1 - 7e-17 61.4 0.0 1.4e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 GAX18970.1 - 1.7e-09 37.7 0.0 4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Luteo_coat PF00894.18 GAX18970.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Luteovirus coat protein PGM_PMM_II PF02879.16 GAX18970.1 - 1.9 9.1 5.2 3.3 8.4 0.5 3.5 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PC-Esterase PF13839.6 GAX18973.1 - 6e-05 22.9 0.4 0.021 14.6 0.0 2.2 1 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF2586 PF10758.9 GAX18973.1 - 0.12 11.5 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) TraL PF07178.11 GAX18974.1 - 0.13 12.7 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 TraL protein adh_short PF00106.25 GAX18975.1 - 2.2e-21 76.2 2.5 4.3e-20 72.0 2.5 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX18975.1 - 1.2e-11 44.6 0.6 3.5e-11 43.1 0.6 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX18975.1 - 8e-09 35.7 0.3 1.2e-08 35.1 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX18975.1 - 7.7e-07 28.8 0.1 1.2e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 GAX18975.1 - 0.00039 19.8 0.1 0.00054 19.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAX18975.1 - 0.0014 18.1 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAX18975.1 - 0.0052 17.0 0.2 0.0099 16.1 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 GAX18975.1 - 0.0088 15.2 0.3 0.013 14.6 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SPACA9 PF15120.6 GAX18975.1 - 0.0094 15.7 0.3 0.014 15.2 0.3 1.2 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 3HCDH_N PF02737.18 GAX18975.1 - 0.015 15.2 0.5 0.026 14.4 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 GAX18975.1 - 0.042 14.5 1.8 0.14 12.8 1.3 2.0 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX18975.1 - 0.16 12.1 1.6 0.68 10.0 1.6 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HEM4 PF02602.15 GAX18976.1 - 3.2e-42 144.5 0.0 3.9e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Hydrolase_4 PF12146.8 GAX18977.1 - 2.3e-13 50.0 0.0 4e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX18977.1 - 5e-11 42.7 0.2 4.3e-10 39.7 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX18977.1 - 4.9e-10 40.4 0.0 1.1e-09 39.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 GAX18977.1 - 0.0028 17.2 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 GAX18977.1 - 0.01 15.7 0.0 0.039 13.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 GAX18977.1 - 0.014 15.2 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 GAX18977.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 GAX18977.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF726 PF05277.12 GAX18977.1 - 0.046 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Esterase PF00756.20 GAX18977.1 - 0.11 12.2 0.0 0.27 10.8 0.0 1.7 1 1 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 GAX18977.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) TcdB_N PF12918.7 GAX18979.1 - 0.035 14.4 0.9 15 6.0 0.1 3.5 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain RNase_T PF00929.24 GAX18980.1 - 3.2e-09 37.6 0.0 4.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Arm-DNA-bind_2 PF12167.8 GAX18981.1 - 0.038 13.9 5.5 0.15 12.0 0.2 3.7 3 1 1 4 4 4 0 Arm DNA-binding domain NAPRTase_N PF17767.1 GAX18981.1 - 0.2 12.1 3.7 0.19 12.2 0.3 2.6 2 1 1 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain IL31 PF15209.6 GAX18981.1 - 0.65 9.8 5.0 6.8 6.5 0.2 3.2 1 1 2 3 3 3 0 Interleukin 31 Methyltransf_23 PF13489.6 GAX18983.1 - 8.2e-22 77.8 0.0 1.1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX18983.1 - 8.1e-18 64.9 0.0 1.9e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX18983.1 - 6.2e-15 55.7 0.0 5.3e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX18983.1 - 3.4e-13 49.5 0.0 5.1e-13 48.9 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX18983.1 - 1.2e-11 45.2 0.0 3.5e-11 43.7 0.0 1.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX18983.1 - 1.4e-11 44.4 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAX18983.1 - 0.0018 17.9 0.0 0.0038 16.8 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 GAX18983.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.8 GAX18983.1 - 0.02 14.0 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Lactamase_B PF00753.27 GAX18984.1 - 4.2e-11 43.2 0.1 1.4e-10 41.6 0.1 1.9 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAX18984.1 - 5.8e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain cNMP_binding PF00027.29 GAX18984.1 - 0.0024 17.9 0.0 0.052 13.6 0.0 3.1 3 1 0 3 3 3 1 Cyclic nucleotide-binding domain REF PF05755.12 GAX18985.1 - 0.069 13.0 0.1 0.087 12.6 0.1 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Sulfotransfer_3 PF13469.6 GAX18986.1 - 2e-06 28.3 0.3 5.6e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 GAX18986.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain DUF1640 PF07798.11 GAX18986.1 - 0.09 12.8 2.4 0.18 11.8 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CN_hydrolase PF00795.22 GAX18987.1 - 2.7e-65 220.3 0.0 3.1e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BTHB PF18410.1 GAX18988.1 - 0.0045 16.8 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 Basic tilted helix bundle domain Ribosomal_L24e PF01246.20 GAX18989.1 - 4.4e-09 36.4 0.1 4.4e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e HAD_SAK_2 PF18143.1 GAX18989.1 - 0.15 12.4 1.0 0.2 12.0 1.0 1.2 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins HMGL-like PF00682.19 GAX18990.1 - 2.7e-86 289.4 0.0 3.9e-86 288.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 GAX18990.1 - 7e-34 116.6 0.1 1.3e-33 115.7 0.1 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4225 PF13988.6 GAX18990.1 - 0.073 12.6 0.0 0.35 10.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4225) 2TM PF13239.6 GAX18991.1 - 0.028 14.7 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 2TM domain CUTL PF16557.5 GAX18992.1 - 9.9 6.4 6.0 2.8 8.2 0.4 2.7 3 0 0 3 3 3 0 CUT1-like DNA-binding domain of SATB SKIP_SNW PF02731.15 GAX18993.1 - 2.2e-63 212.7 2.2 2.2e-63 212.7 2.2 2.5 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.12 GAX18993.1 - 0.0029 17.4 14.1 0.0029 17.4 14.1 1.9 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein PALP PF00291.25 GAX18994.1 - 1.6e-80 270.6 3.8 2e-80 270.4 3.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 GAX18994.1 - 3.6e-41 138.8 0.0 6.6e-23 80.3 0.0 2.9 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Pantoate_ligase PF02569.15 GAX18995.1 - 4e-103 344.3 0.1 4.6e-103 344.1 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase RRM_1 PF00076.22 GAX18996.1 - 1.8e-11 43.7 0.0 6.2e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med26 PF08711.11 GAX18996.1 - 0.00011 22.2 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RRM_5 PF13893.6 GAX18996.1 - 0.00072 19.1 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 GAX18997.1 - 1.4e-101 339.8 0.0 1.4e-101 339.8 0.0 2.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX18997.1 - 3.3e-27 95.2 0.0 2.1e-26 92.6 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding Rotamase PF00639.21 GAX18997.1 - 0.033 15.1 16.9 0.064 14.2 0.1 5.5 5 0 0 5 5 5 0 PPIC-type PPIASE domain Taq-exonuc PF09281.10 GAX18997.1 - 0.66 10.0 4.4 0.22 11.5 0.4 2.3 2 0 0 2 2 2 0 Taq polymerase, exonuclease Kinesin_assoc PF16183.5 GAX18997.1 - 3.9 7.6 29.6 0.12 12.6 2.0 5.4 2 1 1 4 4 4 0 Kinesin-associated XLF PF09302.11 GAX18997.1 - 8.8 6.5 16.2 0.55 10.4 2.9 4.3 2 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Cyclin_N PF00134.23 GAX18998.1 - 8.7e-17 61.1 0.5 1.5e-16 60.3 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX18998.1 - 2.2e-05 24.5 1.2 7.6e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain MBOAT_2 PF13813.6 GAX18999.1 - 8.6e-12 45.2 0.1 2.5e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT PF03062.19 GAX18999.1 - 5.9e-07 29.1 6.2 1.2e-06 28.2 6.2 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF410 PF04190.13 GAX19000.1 - 2.9e-40 138.7 0.0 3.8e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF1541 PF07563.11 GAX19000.1 - 0.079 12.8 0.4 0.27 11.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Exo_endo_phos PF03372.23 GAX19001.1 - 0.00091 18.8 0.0 0.0021 17.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LON_substr_bdg PF02190.16 GAX19002.1 - 1.5e-10 41.3 0.0 3.3e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain Rb_C PF08934.10 GAX19002.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Rb C-terminal domain V-ATPase_C PF03223.15 GAX19003.1 - 2.8e-88 296.8 0.0 3.5e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C MukB_hinge PF16330.5 GAX19003.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 MukB hinge domain Kri1 PF05178.12 GAX19003.1 - 0.097 13.2 1.6 0.14 12.7 0.0 2.1 3 0 0 3 3 3 0 KRI1-like family FG-GAP_2 PF14312.6 GAX19004.1 - 5.2e-89 292.3 33.5 2.3e-17 62.9 1.4 7.1 7 0 0 7 7 7 7 FG-GAP repeat HisK_sensor PF18698.1 GAX19004.1 - 4.6e-05 23.8 3.0 0.037 14.4 0.0 3.8 4 0 0 4 4 4 2 Histidine kinase sensor domain AnfO_nitrog PF09582.10 GAX19004.1 - 0.041 13.2 0.0 30 3.9 0.0 3.4 4 0 0 4 4 4 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DsbC PF11412.8 GAX19004.1 - 0.069 13.2 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Disulphide bond corrector protein DsbC Kelch_3 PF13415.6 GAX19004.1 - 0.17 12.2 9.2 1.9 8.9 0.5 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Pro_Al_protease PF02983.14 GAX19004.1 - 1.1 9.4 5.4 2.5 8.2 0.0 3.9 5 0 0 5 5 5 0 Alpha-lytic protease prodomain FG-GAP PF01839.23 GAX19004.1 - 3 8.0 30.1 0.18 12.0 0.4 6.8 7 0 0 7 7 7 0 FG-GAP repeat PA PF02225.22 GAX19005.1 - 2.1e-07 30.8 0.1 3.5e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 PA domain DZR PF12773.7 GAX19005.1 - 0.0028 17.6 2.9 0.0054 16.7 2.9 1.5 1 0 0 1 1 1 1 Double zinc ribbon ZNRF_3_ecto PF18212.1 GAX19005.1 - 0.0067 16.4 0.2 0.028 14.4 0.1 2.1 2 1 0 2 2 2 1 ZNRF-3 Ectodomain BBP1_C PF15272.6 GAX19005.1 - 0.1 12.4 0.4 0.17 11.7 0.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Chisel PF15355.6 GAX19006.1 - 0.092 13.0 0.6 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel PBP1_TM PF14812.6 GAX19006.1 - 1.8 9.0 47.3 13 6.3 0.5 6.9 1 1 4 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_primase_S PF01896.19 GAX19007.1 - 9.9e-47 159.2 0.0 2.4e-46 158.0 0.0 1.6 1 1 0 1 1 1 1 DNA primase small subunit P53 PF00870.18 GAX19007.1 - 0.028 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 P53 DNA-binding domain GTP1_OBG PF01018.22 GAX19009.1 - 1.7e-33 115.4 8.7 2.3e-33 115.0 8.7 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 GAX19009.1 - 3.8e-23 81.8 0.0 6.2e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX19009.1 - 1.6e-10 40.7 0.0 5.7e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 GAX19009.1 - 2.4e-05 24.3 0.0 0.00069 19.5 0.0 2.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 GAX19009.1 - 7.4e-05 22.4 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAX19009.1 - 0.00013 21.1 0.2 0.039 12.9 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAX19009.1 - 0.00047 20.2 0.0 0.55 10.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Arf PF00025.21 GAX19009.1 - 0.0043 16.5 0.1 0.48 9.9 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 GAX19009.1 - 0.063 13.8 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 GAX19009.1 - 0.098 12.6 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA PF00004.29 GAX19010.1 - 8.2e-89 294.8 0.0 2.4e-43 147.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX19010.1 - 2.3e-24 84.9 2.4 1.1e-12 47.5 0.4 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 GAX19010.1 - 6.7e-14 51.9 0.0 1.7e-05 24.6 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX19010.1 - 2.6e-13 50.7 0.6 0.00025 21.5 0.2 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 GAX19010.1 - 3.1e-10 40.4 0.0 7.9e-05 22.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAX19010.1 - 5e-10 39.7 0.0 0.00016 21.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAX19010.1 - 1.9e-09 37.6 0.0 3.1e-05 24.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 GAX19010.1 - 5.1e-09 36.5 0.0 0.0037 17.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_22 PF13401.6 GAX19010.1 - 5.2e-09 36.5 0.5 0.00055 20.2 0.1 3.9 2 2 0 3 3 3 2 AAA domain AAA_5 PF07728.14 GAX19010.1 - 8.3e-09 35.6 0.1 0.00079 19.4 0.1 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAX19010.1 - 5.5e-08 32.4 0.1 0.01 15.1 0.0 2.8 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 GAX19010.1 - 5.5e-07 30.2 0.0 0.063 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAX19010.1 - 6.3e-07 29.5 0.2 0.26 11.2 0.0 3.6 3 0 0 3 3 3 2 NACHT domain Viral_helicase1 PF01443.18 GAX19010.1 - 1.2e-06 28.4 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 GAX19010.1 - 1.4e-06 28.2 0.2 0.1 12.3 0.0 2.8 2 1 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.6 GAX19010.1 - 3.1e-06 27.6 0.1 0.096 13.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 GAX19010.1 - 3.2e-06 27.1 0.0 0.076 13.0 0.0 3.1 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAX19010.1 - 3.6e-06 26.5 3.0 0.05 13.0 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAX19010.1 - 5.6e-06 26.7 0.0 0.029 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 GAX19010.1 - 1.2e-05 25.3 0.0 0.13 12.1 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain CDC48_N PF02359.18 GAX19010.1 - 1.6e-05 25.0 0.8 4.9e-05 23.4 0.8 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_7 PF12775.7 GAX19010.1 - 1.7e-05 24.4 0.0 0.093 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 GAX19010.1 - 1.9e-05 24.1 0.0 0.098 12.0 0.0 2.8 2 1 0 2 2 2 2 KaiC Zeta_toxin PF06414.12 GAX19010.1 - 2.1e-05 23.9 0.0 0.012 14.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 GAX19010.1 - 3.6e-05 24.3 0.0 0.45 11.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ATPase_2 PF01637.18 GAX19010.1 - 7.8e-05 22.7 0.0 1.4 8.7 0.0 3.4 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Vps4_C PF09336.10 GAX19010.1 - 8e-05 22.6 0.2 0.00064 19.7 0.0 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 GAX19010.1 - 0.00018 20.7 0.2 0.064 12.3 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 GAX19010.1 - 0.00029 20.5 0.2 2.5 7.6 0.1 3.7 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 GAX19010.1 - 0.00037 20.2 0.1 0.94 9.2 0.0 3.0 3 1 0 3 3 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 GAX19010.1 - 0.00043 19.6 0.0 0.99 8.5 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activ_2 PF14532.6 GAX19010.1 - 0.00054 20.1 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 GAX19010.1 - 0.00099 18.9 0.0 1.3 8.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 GAX19010.1 - 0.0014 18.5 0.0 0.71 9.7 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein PhoH PF02562.16 GAX19010.1 - 0.0017 17.9 0.1 2 7.8 0.0 2.8 3 0 0 3 3 2 1 PhoH-like protein AAA_3 PF07726.11 GAX19010.1 - 0.0024 17.7 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 GAX19010.1 - 0.0028 17.5 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 GAX19010.1 - 0.0051 17.0 0.0 8.6 6.4 0.0 3.4 4 0 0 4 4 3 0 Cytidylate kinase-like family DUF2075 PF09848.9 GAX19010.1 - 0.0069 15.7 0.0 0.8 8.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GAX19010.1 - 0.0074 15.4 0.0 1.3 8.0 0.0 2.9 2 1 0 2 2 2 1 Type II/IV secretion system protein Hydin_ADK PF17213.3 GAX19010.1 - 0.0097 16.2 1.7 9.7 6.4 0.0 3.3 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF815 PF05673.13 GAX19010.1 - 0.016 14.4 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Molydop_binding PF01568.21 GAX19010.1 - 0.022 14.8 0.2 0.07 13.2 0.1 1.8 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_19 PF13245.6 GAX19010.1 - 0.038 14.3 0.4 13 6.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain SH3_2 PF07653.17 GAX19010.1 - 0.047 13.4 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain AAA_30 PF13604.6 GAX19010.1 - 0.047 13.4 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 GAX19010.1 - 0.062 13.3 0.1 14 5.7 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 GAX19010.1 - 0.066 13.1 0.0 24 4.8 0.0 3.2 2 0 0 2 2 2 0 NTPase Arteri_nsp7a PF16749.5 GAX19010.1 - 0.1 12.8 0.0 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha ADK PF00406.22 GAX19010.1 - 0.11 12.7 0.1 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase PduV-EutP PF10662.9 GAX19010.1 - 0.11 12.3 0.0 19 5.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAX19010.1 - 0.12 11.8 0.0 4.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IPT PF01745.16 GAX19010.1 - 0.15 11.4 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Glyco_transf_90 PF05686.12 GAX19011.1 - 1.2e-14 54.0 0.0 6.2e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 GHMP_kinases_C PF08544.13 GAX19012.1 - 4.1e-05 23.9 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAX19012.1 - 0.00012 22.2 0.2 0.00024 21.3 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain zf-RanBP PF00641.18 GAX19014.1 - 1.1e-09 37.4 17.9 2.5e-08 33.1 4.9 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 GAX19014.1 - 0.34 10.9 10.2 0.73 9.9 10.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Cytochrom_CIII PF02085.16 GAX19014.1 - 0.76 10.2 7.3 1.5 9.2 7.3 1.4 1 0 0 1 1 1 0 Class III cytochrome C family zf-UBR PF02207.20 GAX19014.1 - 0.81 9.9 4.6 1.4 9.2 0.5 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) V-SNARE_C PF12352.8 GAX19015.1 - 1.4e-09 38.1 1.8 1.4e-09 38.1 1.8 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus TSNAXIP1_N PF15739.5 GAX19015.1 - 0.0066 16.8 0.1 0.051 13.9 0.0 2.1 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus HeLo PF14479.6 GAX19015.1 - 0.018 14.9 1.2 0.25 11.2 1.2 2.0 1 1 0 1 1 1 0 Prion-inhibition and propagation kleA_kleC PF17383.2 GAX19015.1 - 0.063 13.6 2.1 0.1 13.0 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Rotamase PF00639.21 GAX19015.1 - 0.091 13.7 1.2 0.7 10.9 0.1 2.4 2 1 1 3 3 3 0 PPIC-type PPIASE domain Laminin_II PF06009.12 GAX19015.1 - 0.11 12.5 1.5 6.6 6.8 0.2 2.9 2 1 0 2 2 2 0 Laminin Domain II DASH_Dad1 PF08649.10 GAX19015.1 - 0.11 12.7 0.4 7.1 6.9 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad1 Esterase PF00756.20 GAX19016.1 - 1.1e-45 156.3 0.0 1.8e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 GAX19016.1 - 0.019 14.3 0.0 0.067 12.5 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 GAX19016.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 GAX19016.1 - 0.071 12.0 0.0 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Ipi1_N PF12333.8 GAX19017.1 - 0.0028 18.2 3.7 0.017 15.7 0.0 3.8 4 1 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.7 GAX19017.1 - 0.019 15.0 1.5 0.099 12.7 0.1 2.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX19017.1 - 0.022 15.0 1.9 2 8.9 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat DEAD PF00270.29 GAX19018.1 - 5.7e-38 130.4 0.1 2.5e-37 128.3 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX19018.1 - 4.6e-24 84.9 0.1 1.3e-23 83.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX19018.1 - 1.7e-05 24.9 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SAM_2 PF07647.17 GAX19019.1 - 4.4e-06 26.7 0.8 6.2e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) FKBP_C PF00254.28 GAX19019.1 - 3.3e-05 24.1 0.0 7e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SAM_1 PF00536.30 GAX19019.1 - 0.01 16.3 0.2 0.027 14.9 0.2 1.8 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) URO-D PF01208.17 GAX19020.1 - 2.8e-108 362.1 0.0 3.3e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PGDH_C PF16896.5 GAX19020.1 - 0.12 12.3 0.2 6.2 6.8 0.0 2.3 1 1 1 2 2 2 0 Phosphogluconate dehydrogenase (decarboxylating) C-term Lipase_3 PF01764.25 GAX19021.1 - 1.9e-11 44.0 0.0 3.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PC_rep PF01851.22 GAX19021.1 - 0.067 13.7 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Proteasome/cyclosome repeat COPI_assoc PF08507.10 GAX19022.1 - 3e-09 37.0 4.3 3.8e-09 36.7 4.3 1.1 1 0 0 1 1 1 1 COPI associated protein DUF3817 PF12823.7 GAX19022.1 - 1.1 10.1 11.4 0.31 11.9 8.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) WW PF00397.26 GAX19023.1 - 3.2e-126 411.0 67.3 1.1e-10 41.4 0.4 13.7 13 0 0 13 13 13 13 WW domain Sec16_C PF12931.7 GAX19023.1 - 4.6e-32 111.9 0.1 7.6e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Glyco_hyd_101C PF17451.2 GAX19023.1 - 1.5e-13 51.1 38.5 0.01 16.1 0.2 13.2 13 0 0 13 13 13 5 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 GAX19023.1 - 2.7e-08 33.3 3.8 5.5 7.1 0.0 8.1 8 0 0 8 8 8 2 PQQ enzyme repeat PQQ_2 PF13360.6 GAX19023.1 - 6e-08 32.6 23.7 0.059 13.0 0.3 6.9 5 3 0 6 6 6 5 PQQ-like domain Sec16 PF12932.7 GAX19023.1 - 0.035 14.7 2.2 0.083 13.5 0.2 2.7 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region WW_1 PF18507.1 GAX19023.1 - 0.65 9.7 0.0 0.65 9.7 0.0 5.2 6 0 0 6 6 6 0 WW domain HMG_box PF00505.19 GAX19024.1 - 2.6e-08 34.2 5.4 0.00066 20.0 2.0 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX19024.1 - 5.3e-07 30.1 4.2 0.0041 17.7 1.5 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 GAX19024.1 - 0.084 12.9 5.3 0.077 13.0 3.8 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Silic_transp PF03842.13 GAX19025.1 - 3.9e-172 573.1 23.7 4.4e-172 572.9 23.7 1.0 1 0 0 1 1 1 1 Silicon transporter MORN PF02493.20 GAX19026.1 - 4.2e-07 29.5 0.3 5.3e-06 26.0 0.1 2.5 2 0 0 2 2 2 1 MORN repeat MORN PF02493.20 GAX19027.1 - 6.4e-36 120.1 49.5 7e-07 28.8 0.1 8.4 8 0 0 8 8 8 8 MORN repeat DUF1325 PF07039.11 GAX19027.1 - 0.066 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 SGF29 tudor-like domain MORN PF02493.20 GAX19028.1 - 9.8e-77 248.5 153.0 1.2e-05 24.9 2.1 22.4 22 0 0 22 22 22 20 MORN repeat DUF4124 PF13511.6 GAX19028.1 - 1.5 9.2 12.9 0.11 12.9 0.4 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4124) MORN PF02493.20 GAX19029.1 - 7.1e-30 101.1 39.8 4e-07 29.6 1.0 7.6 7 0 0 7 7 7 7 MORN repeat Nucleoporin_FG2 PF15967.5 GAX19029.1 - 0.11 11.0 5.7 0.16 10.4 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region MPS2 PF17060.5 GAX19029.1 - 0.27 10.5 4.7 0.48 9.6 4.7 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF489 PF04356.12 GAX19029.1 - 0.31 11.0 4.2 0.46 10.5 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) XhlA PF10779.9 GAX19029.1 - 2 8.6 5.1 11 6.3 0.2 2.5 1 1 1 2 2 2 0 Haemolysin XhlA V_ATPase_I PF01496.19 GAX19029.1 - 3.9 5.3 6.8 5.3 4.8 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HMG_box PF00505.19 GAX19030.1 - 2.1e-15 56.9 6.1 2.1e-15 56.9 6.1 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX19030.1 - 4.6e-10 40.0 7.0 4.6e-10 40.0 7.0 1.8 1 1 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 GAX19030.1 - 0.12 12.4 8.2 0.61 10.1 8.2 2.2 1 1 0 1 1 1 0 HMG (high mobility group) box 5 PSI_PsaF PF02507.15 GAX19030.1 - 0.85 9.4 3.4 1.5 8.6 3.4 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Hep_59 PF07052.11 GAX19031.1 - 4.1e-06 27.5 0.6 4.1e-06 27.5 0.6 2.5 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF2378 PF09536.10 GAX19031.1 - 0.018 14.9 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) DUF2922 PF11148.8 GAX19031.1 - 0.047 13.4 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) PBP1_TM PF14812.6 GAX19031.1 - 0.31 11.4 4.1 1.1 9.6 4.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mpv17_PMP22 PF04117.12 GAX19032.1 - 0.00022 21.4 0.1 0.00022 21.4 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Tim44 PF04280.15 GAX19033.1 - 1.1e-25 90.5 0.1 2.7e-25 89.2 0.1 1.6 1 0 0 1 1 1 1 Tim44-like domain HMG_box PF00505.19 GAX19033.1 - 0.062 13.7 0.3 0.2 12.1 0.3 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box Ribosomal_S21 PF01165.20 GAX19033.1 - 0.076 12.7 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 GlutR_dimer PF00745.20 GAX19033.1 - 0.34 11.4 3.3 14 6.2 1.4 3.3 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain YtxH PF12732.7 GAX19033.1 - 0.49 11.0 2.7 5.1 7.7 0.1 2.5 2 0 0 2 2 2 0 YtxH-like protein XhlA PF10779.9 GAX19033.1 - 2.1 8.6 5.8 1.7 8.9 1.0 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Fe_bilin_red PF05996.12 GAX19034.1 - 5.5e-45 153.8 0.3 7e-45 153.5 0.3 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Fe_bilin_red PF05996.12 GAX19035.1 - 1.5e-57 194.9 2.4 2e-57 194.5 2.4 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase ADH_zinc_N PF00107.26 GAX19036.1 - 5e-17 62.1 0.1 9.6e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAX19036.1 - 1.3e-16 61.9 0.0 2.9e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX19036.1 - 1.1e-07 31.7 0.1 9.3e-07 28.7 0.1 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAX19036.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase IMS PF00817.20 GAX19036.1 - 0.092 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 impB/mucB/samB family MBD PF01429.19 GAX19037.1 - 0.015 15.0 4.3 37 4.1 0.0 5.2 6 0 0 6 6 6 0 Methyl-CpG binding domain NopRA1 PF16201.5 GAX19038.1 - 1e-29 103.6 0.4 4.6e-29 101.5 0.1 2.4 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 PPR_2 PF13041.6 GAX19039.1 - 3.7e-14 52.6 1.3 1.4e-06 28.4 0.0 4.8 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.6 GAX19039.1 - 4e-12 46.0 0.0 5.9e-08 32.7 0.0 3.5 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX19039.1 - 1.4e-11 44.2 0.5 1.9e-05 24.1 0.0 2.9 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX19039.1 - 5.1e-05 23.2 11.3 0.077 13.3 0.1 5.2 4 1 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 GAX19039.1 - 0.024 14.3 0.2 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 PPR repeat zf-met2 PF12907.7 GAX19039.1 - 0.067 13.3 0.1 0.067 13.3 0.1 2.3 3 0 0 3 3 3 0 Zinc-binding Helo_like_N PF17111.5 GAX19039.1 - 0.14 11.5 0.0 2.5 7.4 0.0 2.5 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins Eapp_C PF10238.9 GAX19040.1 - 1.3e-42 145.4 11.9 5.8e-42 143.3 11.9 2.0 1 1 0 1 1 1 1 E2F-associated phosphoprotein Peptidase_C6 PF00851.18 GAX19040.1 - 0.0053 15.7 0.4 0.007 15.3 0.4 1.1 1 0 0 1 1 1 1 Helper component proteinase CSN8_PSD8_EIF3K PF10075.9 GAX19041.1 - 0.0061 16.5 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family EF-hand_6 PF13405.6 GAX19042.1 - 2.4e-09 36.4 0.8 0.00049 19.8 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 GAX19042.1 - 1.6e-08 33.5 1.1 0.0024 17.3 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAX19042.1 - 1.1e-06 27.8 1.3 0.002 17.5 0.7 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAX19042.1 - 1.4e-06 28.7 0.5 5.5e-06 26.7 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX19042.1 - 0.0004 20.2 0.6 0.6 10.0 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair Myc_N PF01056.18 GAX19044.1 - 0.011 15.6 0.2 0.011 15.6 0.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF819 PF05684.12 GAX19045.1 - 2.6e-67 227.5 17.5 3.1e-67 227.3 17.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF819) Dicer_N PF17895.1 GAX19045.1 - 0.013 15.3 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain Romo1 PF10247.9 GAX19045.1 - 0.21 11.9 4.3 0.73 10.2 4.3 2.0 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 ABC1 PF03109.16 GAX19046.1 - 1.3e-25 89.8 0.0 2.4e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GAX19046.1 - 0.00017 21.0 0.1 0.059 12.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GAX19046.1 - 0.00048 20.1 0.2 0.0078 16.2 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 GAX19046.1 - 0.0036 16.9 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PI3_PI4_kinase PF00454.27 GAX19046.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Pkinase_Tyr PF07714.17 GAX19046.1 - 0.11 11.8 0.0 6.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase AA_kinase PF00696.28 GAX19047.1 - 2.4e-07 30.6 0.0 4.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family SelA PF03841.13 GAX19047.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Peptidase_S8 PF00082.22 GAX19048.1 - 1.1e-27 97.1 2.1 1.5e-26 93.3 0.9 2.0 2 0 0 2 2 2 2 Subtilase family WAP PF00095.21 GAX19049.1 - 0.26 11.7 23.9 2.2 8.7 0.4 4.5 4 0 0 4 4 4 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF5543 PF17697.1 GAX19049.1 - 4.5 7.6 10.6 0.18 12.1 1.7 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5543) PAN_4 PF14295.6 GAX19049.1 - 8.9 6.3 14.9 12 5.9 0.1 4.7 4 0 0 4 4 4 0 PAN domain LRR_8 PF13855.6 GAX19050.1 - 7.6e-09 35.2 9.0 4.6e-05 23.1 1.4 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAX19050.1 - 9.1e-07 29.1 6.8 0.00048 20.5 0.7 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAX19050.1 - 0.017 15.1 4.3 3.8 7.8 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich repeat WAP PF00095.21 GAX19050.1 - 0.031 14.6 2.3 0.031 14.6 2.3 3.6 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' LRR_1 PF00560.33 GAX19050.1 - 0.061 13.9 11.8 8.4 7.4 0.2 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat Prokineticin PF06607.11 GAX19050.1 - 0.063 13.6 5.2 3.1 8.2 0.7 2.5 2 0 0 2 2 2 0 Prokineticin PAN_4 PF14295.6 GAX19050.1 - 0.07 13.0 0.1 0.07 13.0 0.1 3.4 3 0 0 3 3 3 0 PAN domain RRM_1 PF00076.22 GAX19051.1 - 1.5e-50 168.8 0.9 4e-15 55.4 0.1 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAX19051.1 - 1.1e-07 31.7 0.4 0.0059 16.6 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 GAX19051.1 - 0.0059 16.4 0.3 0.45 10.3 0.1 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) TFIIA PF03153.13 GAX19051.1 - 0.027 14.5 36.4 0.2 11.6 21.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_7 PF16367.5 GAX19051.1 - 0.073 13.2 0.3 3.4 7.9 0.0 3.7 4 1 0 4 4 4 0 RNA recognition motif adh_short PF00106.25 GAX19052.1 - 1.1e-28 100.0 0.0 1.4e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX19052.1 - 6.8e-19 68.4 0.0 8.8e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX19052.1 - 3.2e-09 37.0 0.0 4.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX19052.1 - 0.0027 17.2 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAX19052.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) XPC-binding PF09280.11 GAX19052.1 - 0.27 11.0 1.9 13 5.6 0.1 3.2 3 0 0 3 3 3 0 XPC-binding domain Patched PF02460.18 GAX19053.1 - 3.7e-100 336.3 0.1 5.6e-100 335.7 0.1 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 GAX19053.1 - 1.9e-37 128.5 18.5 2.5e-37 128.0 1.3 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 GAX19053.1 - 1.6e-06 27.3 19.3 0.00017 20.7 2.6 2.5 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.19 GAX19053.1 - 2.9e-06 25.3 9.9 9.9e-05 20.2 8.1 2.3 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family Lin0512_fam PF09585.10 GAX19054.1 - 1.5e-36 124.9 1.3 1.7e-36 124.7 1.3 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) Lin0512_fam PF09585.10 GAX19055.1 - 6.3e-36 122.9 0.1 7.3e-36 122.7 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) DUF2292 PF10055.9 GAX19055.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) Alpha_kinase PF02816.18 GAX19056.1 - 8.1e-44 150.0 1.1 1e-43 149.6 1.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family Proteasome PF00227.26 GAX19057.1 - 9.9e-18 64.3 0.6 3.2e-17 62.6 0.6 1.8 1 1 0 1 1 1 1 Proteasome subunit Suf PF05843.14 GAX19059.1 - 2.3e-20 73.8 20.7 5.5e-09 36.4 1.5 7.5 3 2 4 7 7 7 6 Suppressor of forked protein (Suf) HAT PF02184.16 GAX19059.1 - 9.3e-20 70.3 42.7 0.00015 21.7 0.0 12.0 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 GAX19059.1 - 1.1e-18 66.3 31.7 0.0096 16.7 0.1 12.2 5 3 8 13 13 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAX19059.1 - 7.4e-16 58.4 10.1 0.021 15.3 0.0 7.2 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX19059.1 - 0.00032 20.7 14.0 24 5.5 0.1 8.2 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX19059.1 - 0.00056 20.0 9.9 0.24 11.5 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX19059.1 - 0.0011 19.6 21.6 0.065 13.9 0.2 6.9 7 2 1 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX19059.1 - 0.0021 18.1 31.4 1.7 9.0 0.1 9.7 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAX19059.1 - 0.0027 18.0 3.3 6 7.5 0.0 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAX19059.1 - 0.0083 16.1 22.0 1.9 8.5 0.2 6.2 5 2 1 6 6 6 3 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 GAX19059.1 - 0.016 15.8 25.6 15 6.5 0.0 10.3 12 1 0 12 12 11 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX19059.1 - 0.11 12.4 5.1 27 4.8 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX19059.1 - 0.28 11.5 19.8 0.47 10.8 1.4 7.0 7 1 1 8 8 7 0 Tetratricopeptide repeat MIT PF04212.18 GAX19059.1 - 0.39 10.8 8.1 1.6 8.9 1.9 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain 3HCDH_N PF02737.18 GAX19060.1 - 3.6e-60 202.9 1.4 7.2e-60 201.9 1.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 GAX19060.1 - 2.8e-38 131.7 1.2 4.8e-38 130.9 0.1 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 GAX19060.1 - 9.6e-27 93.5 0.0 7.5e-18 64.9 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 GAX19060.1 - 4.1e-25 89.0 0.5 1.1e-24 87.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Sacchrp_dh_NADP PF03435.18 GAX19060.1 - 0.00016 22.0 1.9 0.00019 21.7 0.3 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 GAX19060.1 - 0.00082 19.9 0.2 0.003 18.1 0.2 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAX19060.1 - 0.0039 17.4 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_31 PF13847.6 GAX19060.1 - 0.0086 15.9 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAD_Gly3P_dh_N PF01210.23 GAX19060.1 - 0.0096 15.9 0.2 0.023 14.7 0.2 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 GAX19060.1 - 0.016 14.9 0.1 0.037 13.7 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 GAX19060.1 - 0.021 15.1 0.2 0.058 13.7 0.2 1.8 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 GAX19060.1 - 0.042 14.4 0.1 0.14 12.8 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX19060.1 - 0.042 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase PglD_N PF17836.1 GAX19060.1 - 0.051 14.2 0.5 0.28 11.9 0.5 2.3 1 1 0 1 1 1 0 PglD N-terminal domain Shikimate_DH PF01488.20 GAX19060.1 - 0.072 13.1 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 GAX19060.1 - 0.12 12.1 0.5 0.22 11.2 0.2 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAP_epimerase PF01678.19 GAX19061.1 - 4.7e-68 226.9 0.0 1.7e-35 121.8 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 GAX19061.1 - 0.0009 18.8 0.0 0.0015 18.0 0.0 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Complex1_LYR PF05347.15 GAX19062.1 - 5.1e-05 23.2 0.7 7.9e-05 22.6 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Silic_transp PF03842.13 GAX19063.1 - 1.9e-174 580.7 24.2 2.2e-174 580.5 24.3 1.0 1 0 0 1 1 1 1 Silicon transporter TMEM192 PF14802.6 GAX19063.1 - 0.86 8.7 11.4 0.77 8.8 0.8 3.3 2 1 1 3 3 3 0 TMEM192 family Silic_transp PF03842.13 GAX19064.1 - 1.3e-171 571.4 22.8 1.4e-171 571.3 22.8 1.0 1 0 0 1 1 1 1 Silicon transporter RRM_2 PF04059.12 GAX19065.1 - 5.5e-37 125.9 0.2 8.9e-37 125.2 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 GAX19065.1 - 5.5e-11 42.1 0.1 0.00044 20.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 GAX19065.1 - 0.0026 17.8 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family DUF4523 PF15023.6 GAX19065.1 - 0.22 11.3 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) His_biosynth PF00977.21 GAX19066.1 - 4.7e-41 140.7 1.3 5.5e-39 134.0 1.1 3.6 1 1 1 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 GAX19066.1 - 3e-22 79.3 0.0 6.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GAX19066.1 - 7.1e-09 35.5 0.0 1.9e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 GAX19066.1 - 5e-08 33.0 0.0 0.0014 18.6 0.0 2.8 3 0 0 3 3 3 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 GAX19066.1 - 0.013 15.2 0.2 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 Peptidase C26 ABC_tran PF00005.27 GAX19067.1 - 1.3e-26 93.7 0.0 2.1e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAX19067.1 - 2.9e-11 43.2 16.4 4.9e-11 42.4 16.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GAX19067.1 - 6.4e-08 32.8 0.0 6.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 GAX19067.1 - 0.00019 20.6 14.3 0.00027 20.2 14.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 GAX19067.1 - 0.00076 19.9 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAX19067.1 - 0.00098 18.6 0.1 0.032 13.7 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAX19067.1 - 0.0014 19.2 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAX19067.1 - 0.0018 18.2 0.4 0.0089 15.9 0.1 2.3 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 GAX19067.1 - 0.0022 18.3 0.1 0.0071 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX19067.1 - 0.035 13.4 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 GAX19067.1 - 0.038 13.2 0.1 0.54 9.4 0.1 2.2 1 1 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 GAX19067.1 - 0.041 13.4 0.2 0.087 12.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX19067.1 - 0.043 13.6 0.2 0.093 12.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 GAX19067.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAX19067.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 GAX19067.1 - 0.18 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ist1 PF03398.14 GAX19068.1 - 1.4e-50 171.4 4.2 1.6e-50 171.2 4.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ank_2 PF12796.7 GAX19069.1 - 6.9e-31 106.7 0.1 3.5e-11 43.5 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 GAX19069.1 - 7.4e-23 81.1 7.6 7.4e-23 81.1 7.6 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 GAX19069.1 - 5.2e-20 71.5 5.0 7.3e-07 29.6 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX19069.1 - 3.4e-15 55.9 0.1 0.0004 20.6 0.0 4.9 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX19069.1 - 5.5e-14 51.9 1.9 0.0045 17.4 0.0 5.9 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 GAX19069.1 - 7.3e-12 44.4 0.1 0.088 13.4 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat LPMO_10 PF03067.15 GAX19070.1 - 4.3e-29 102.6 0.3 4.3e-29 102.6 0.3 1.7 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Sulfotransfer_3 PF13469.6 GAX19074.1 - 1.4e-20 74.7 3.7 4.6e-20 72.9 0.3 3.1 2 2 0 2 2 2 1 Sulfotransferase family TPR_11 PF13414.6 GAX19074.1 - 0.00095 18.8 0.0 0.01 15.5 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 GAX19074.1 - 0.0028 17.6 0.0 12 6.3 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat BORCS8 PF10167.9 GAX19074.1 - 0.0067 16.3 0.2 0.76 9.7 0.1 2.6 3 0 0 3 3 3 1 BLOC-1-related complex sub-unit 8 TPR_17 PF13431.6 GAX19074.1 - 0.007 16.7 0.1 0.068 13.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 GAX19074.1 - 0.0098 14.8 0.2 0.015 14.2 0.2 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Sulfotransfer_1 PF00685.27 GAX19074.1 - 0.01 15.4 0.2 0.03 13.8 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase domain TPR_14 PF13428.6 GAX19074.1 - 0.033 15.0 0.1 1.1 10.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX19074.1 - 0.091 12.9 0.1 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat IQ PF00612.27 GAX19075.1 - 4.6e-55 178.3 152.5 0.0011 18.6 0.0 29.1 29 0 0 29 29 29 26 IQ calmodulin-binding motif UPF0182 PF03699.13 GAX19077.1 - 0.15 10.1 1.4 0.3 9.2 1.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Choline_transpo PF04515.12 GAX19078.1 - 1.1e-56 192.4 22.3 1.1e-56 192.4 22.3 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter zf-C3HC4_3 PF13920.6 GAX19079.1 - 5.5e-07 29.4 6.1 9.9e-07 28.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX19079.1 - 9.2e-06 25.4 6.4 1.8e-05 24.5 6.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAX19079.1 - 0.0052 17.1 7.0 0.0097 16.2 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 GAX19079.1 - 0.082 12.8 4.7 0.17 11.7 4.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 GAX19079.1 - 0.55 10.1 7.4 1 9.3 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 GAX19079.1 - 1.1 9.4 6.1 2.3 8.4 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) ABC_tran PF00005.27 GAX19080.1 - 5.7e-54 182.3 0.0 9.3e-33 113.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAX19080.1 - 3e-47 161.5 26.2 2.4e-28 99.6 8.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAX19080.1 - 2.6e-09 36.8 0.6 0.071 12.5 0.0 4.5 4 1 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAX19080.1 - 5e-07 30.3 0.2 0.046 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAX19080.1 - 3.1e-06 27.2 0.0 0.2 11.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAX19080.1 - 4e-06 27.5 0.4 0.0098 16.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 GAX19080.1 - 6.9e-06 26.4 0.0 0.12 12.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAX19080.1 - 1.5e-05 24.6 0.1 0.27 11.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX19080.1 - 2.6e-05 24.2 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAX19080.1 - 2.8e-05 24.2 0.0 0.018 15.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 GAX19080.1 - 5.1e-05 23.5 0.3 0.0091 16.1 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain NACHT PF05729.12 GAX19080.1 - 0.00065 19.7 0.5 2.4 8.1 0.0 3.2 3 0 0 3 3 3 2 NACHT domain AAA_30 PF13604.6 GAX19080.1 - 0.0015 18.2 0.0 0.32 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 GAX19080.1 - 0.0032 16.9 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 GAX19080.1 - 0.0038 16.8 3.0 10 5.7 0.1 3.9 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 GAX19080.1 - 0.0042 17.1 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 GAX19080.1 - 0.017 14.7 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 GAX19080.1 - 0.033 13.4 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAX19080.1 - 0.039 13.5 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAX19080.1 - 0.044 14.2 0.0 18 5.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 GAX19080.1 - 0.059 13.6 0.0 8 6.7 0.0 3.3 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 GAX19080.1 - 0.064 12.5 0.1 12 5.1 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 GAX19080.1 - 0.073 12.0 0.1 0.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 GAX19080.1 - 0.087 12.9 0.1 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain VirJ PF06057.11 GAX19080.1 - 0.093 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Pox_A32 PF04665.12 GAX19080.1 - 0.17 11.3 0.7 30 4.0 0.0 3.0 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_33 PF13671.6 GAX19080.1 - 0.18 11.9 0.4 38 4.4 0.1 3.0 2 2 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAX19080.1 - 1.1 9.3 3.3 15 5.6 0.3 2.8 3 0 0 3 3 2 0 Dynamin family Prominin PF05478.11 GAX19081.1 - 0.029 12.4 3.5 0.043 11.8 3.5 1.2 1 0 0 1 1 1 0 Prominin ptaRNA1_toxin PF12703.7 GAX19081.1 - 0.035 14.1 0.5 0.035 14.1 0.5 2.0 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system DUF2509 PF10713.9 GAX19081.1 - 0.081 13.0 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) PIN_2 PF10130.9 GAX19081.1 - 0.13 12.4 1.7 0.25 11.6 0.3 2.2 2 1 0 2 2 2 0 PIN domain DUF948 PF06103.11 GAX19081.1 - 3.3 8.0 5.9 14 6.0 1.1 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF525 PF04379.14 GAX19082.1 - 9.2e-08 32.2 3.1 1.6e-07 31.5 0.0 2.6 3 0 0 3 3 3 1 ApaG domain Elongin_A PF06881.11 GAX19082.1 - 0.14 12.7 0.9 0.26 11.8 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ank_5 PF13857.6 GAX19083.1 - 7.3e-15 54.8 1.2 5.3e-06 26.6 0.1 3.9 2 1 2 4 4 3 3 Ankyrin repeats (many copies) AAA PF00004.29 GAX19083.1 - 9e-15 55.3 0.1 1e-13 51.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.7 GAX19083.1 - 1.9e-12 47.6 0.1 1.7e-05 25.3 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19083.1 - 7.9e-10 39.1 0.1 0.00076 20.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19083.1 - 3.5e-09 36.1 1.1 0.06 13.9 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX19083.1 - 2.8e-05 24.4 4.4 1.2 9.7 0.7 4.9 4 1 0 4 4 3 1 Ankyrin repeat AAA_22 PF13401.6 GAX19083.1 - 4.6e-05 23.7 0.0 0.014 15.6 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 GAX19083.1 - 0.0079 16.4 0.5 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX19083.1 - 0.0093 16.4 0.1 0.052 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain YbaB_DNA_bd PF02575.16 GAX19083.1 - 0.015 15.5 0.7 0.043 14.1 0.1 2.1 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family AAA_5 PF07728.14 GAX19083.1 - 0.019 15.0 0.4 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX19083.1 - 0.037 13.4 0.0 0.075 12.4 0.0 1.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAX19083.1 - 0.038 13.7 0.2 0.13 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX19083.1 - 0.045 14.3 0.0 0.16 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAX19083.1 - 0.08 12.6 0.1 2.4 7.8 0.1 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 GAX19083.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 GAX19083.1 - 0.12 12.5 0.0 0.68 10.1 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 GAX19083.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Ank_5 PF13857.6 GAX19084.1 - 9.2e-18 64.1 4.5 6.3e-09 35.9 1.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX19084.1 - 1.4e-11 44.8 1.9 3.3e-07 30.8 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19084.1 - 5.1e-10 39.7 0.4 0.0023 18.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19084.1 - 1.9e-07 30.8 0.8 0.15 12.7 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 GAX19084.1 - 5.5e-07 29.7 1.9 1 9.9 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat AAA PF00004.29 GAX19084.1 - 0.00042 20.8 0.0 0.00087 19.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX19084.1 - 0.0081 16.6 2.9 0.03 14.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAX19084.1 - 0.036 14.1 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX19084.1 - 0.07 12.3 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CDC45 PF02724.14 GAX19085.1 - 1.2e-117 393.9 9.0 5e-116 388.5 9.0 2.5 1 1 0 1 1 1 1 CDC45-like protein Rho_N PF07498.12 GAX19085.1 - 0.063 13.2 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Apt1 PF10351.9 GAX19085.1 - 0.34 9.7 6.6 0.55 9.0 6.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 GAX19085.1 - 0.38 10.1 33.5 0.59 9.5 33.5 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GAX19085.1 - 6 5.5 11.0 8.9 5.0 11.0 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GAX19085.1 - 9.2 4.3 31.8 16 3.6 31.8 1.3 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 GAX19086.1 - 5.2e-59 199.8 0.0 7.3e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19086.1 - 1.3e-30 106.6 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX19086.1 - 0.005 16.2 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAX19086.1 - 0.0061 15.9 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX19086.1 - 0.033 14.1 0.1 0.56 10.1 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 GAX19087.1 - 6e-23 81.3 26.3 1.2e-17 63.8 6.1 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 GAX19087.1 - 0.044 12.1 0.1 0.093 11.0 0.1 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PT-VENN PF04829.13 GAX19087.1 - 0.093 12.8 1.0 0.26 11.4 1.0 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Rhomboid PF01694.22 GAX19088.1 - 9.9e-33 113.3 9.5 9.9e-33 113.3 9.5 1.9 2 0 0 2 2 2 1 Rhomboid family 4HBT PF03061.22 GAX19089.1 - 4.1e-07 30.3 0.0 0.00059 20.1 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_3 PF13622.6 GAX19089.1 - 1e-05 25.9 0.0 0.00033 21.0 0.0 2.1 2 0 0 2 2 2 1 Thioesterase-like superfamily ADH_zinc_N_2 PF13602.6 GAX19090.1 - 4.8e-06 27.6 0.0 1.1e-05 26.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAX19090.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Retinal PF15449.6 GAX19090.1 - 1.3 6.7 7.7 1.8 6.2 7.7 1.1 1 0 0 1 1 1 0 Retinal protein SR-25 PF10500.9 GAX19090.1 - 3 7.4 17.0 6.1 6.4 17.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GTP_EFTU PF00009.27 GAX19092.1 - 2.2e-31 108.9 0.0 5.7e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAX19092.1 - 3.8e-16 59.1 0.0 1.8e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 GAX19092.1 - 1.5e-06 28.3 0.4 9.1e-06 25.7 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAX19092.1 - 3.6e-06 27.3 3.2 0.058 13.8 0.1 3.1 2 1 0 2 2 2 2 Elongation factor Tu domain 2 Roc PF08477.13 GAX19092.1 - 0.00022 21.4 1.9 0.11 12.7 0.0 3.2 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX19092.1 - 0.019 14.5 0.0 0.069 12.7 0.0 2.0 1 1 1 2 2 2 0 Ras family SRPRB PF09439.10 GAX19092.1 - 1.1 8.7 4.4 2.3 7.6 0.1 2.9 2 1 0 3 3 3 0 Signal recognition particle receptor beta subunit Peptidase_M24 PF00557.24 GAX19093.1 - 1.4e-52 178.4 0.0 1.9e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_21 PF05050.12 GAX19094.1 - 9.8e-08 32.2 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Thioredoxin PF00085.20 GAX19095.1 - 4.3e-23 81.3 0.0 5.1e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 GAX19095.1 - 4.2e-06 26.5 0.0 5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX19095.1 - 6.5e-06 26.6 0.1 0.00033 21.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GAX19095.1 - 4.5e-05 23.0 0.0 5.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAX19095.1 - 0.00013 22.3 0.0 0.0029 17.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.6 GAX19095.1 - 0.00065 19.6 0.0 0.00066 19.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 GAX19095.1 - 0.0034 17.3 0.1 0.0047 16.9 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 GAX19095.1 - 0.0051 17.0 0.1 0.012 15.9 0.1 1.7 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 GAX19095.1 - 0.0089 16.2 0.1 0.021 15.0 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAX19095.1 - 0.017 15.1 0.0 0.048 13.7 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin domain DUF1947 PF09183.10 GAX19095.1 - 0.03 14.6 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Redoxin PF08534.10 GAX19095.1 - 0.057 13.1 0.1 0.12 12.1 0.1 1.5 1 1 1 2 2 2 0 Redoxin HMG_box_2 PF09011.10 GAX19098.1 - 3.5e-05 24.3 0.1 0.12 13.0 0.0 2.7 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.19 GAX19098.1 - 0.00031 21.1 0.1 0.22 12.0 0.0 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box LRR_1 PF00560.33 GAX19099.1 - 0.0029 17.9 0.8 3.7 8.5 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich Repeat LRRNT_2 PF08263.12 GAX19099.1 - 0.051 13.9 0.5 0.097 13.0 0.5 1.4 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 GAX19099.1 - 0.12 12.8 3.2 0.45 11.0 2.5 2.2 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX19099.1 - 0.23 11.2 1.8 3.6 7.4 1.4 2.6 2 1 1 3 3 3 0 Leucine rich repeat 2-oxoacid_dh PF00198.23 GAX19100.1 - 1.3e-44 152.4 0.0 1.6e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX19100.1 - 2.1e-14 53.1 0.2 4.7e-14 52.0 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAX19100.1 - 4e-13 49.5 0.3 1e-12 48.2 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain Metallophos PF00149.28 GAX19101.1 - 2.9e-11 44.3 0.0 5.5e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase rRNA_methylase PF06962.12 GAX19102.1 - 7.6e-22 77.8 0.0 1.7e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_25 PF13649.6 GAX19102.1 - 0.0033 18.1 0.0 0.0082 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX19102.1 - 0.0086 15.9 0.1 0.025 14.3 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain SAM_MT PF04445.13 GAX19102.1 - 0.01 15.3 0.2 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 Putative SAM-dependent methyltransferase Methyltransf_32 PF13679.6 GAX19102.1 - 0.032 14.2 0.7 0.082 12.9 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain NIR_SIR PF01077.22 GAX19104.1 - 1.1e-50 171.2 0.0 1.5e-43 148.1 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 GAX19104.1 - 4.8e-27 93.6 0.0 3.3e-14 52.5 0.0 2.8 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Peptidase_S8 PF00082.22 GAX19105.1 - 7.7e-38 130.4 7.7 8.2e-37 127.1 7.7 2.1 1 1 0 1 1 1 1 Subtilase family Phosphonate-bd PF12974.7 GAX19105.1 - 0.034 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Inhibitor_I9 PF05922.16 GAX19105.1 - 0.085 13.5 0.1 2 9.1 0.1 2.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 LPMO_10 PF03067.15 GAX19106.1 - 9.9e-32 111.2 0.8 1.4e-31 110.6 0.8 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Toxin_12 PF07740.12 GAX19106.1 - 0.0024 18.5 10.3 0.0024 18.5 10.3 3.0 2 1 1 3 3 3 1 Ion channel inhibitory toxin Cwf_Cwc_15 PF04889.12 GAX19107.1 - 0.38 10.5 6.2 0.56 9.9 6.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EF-hand_4 PF12763.7 GAX19108.1 - 2e-14 53.4 0.0 3.6e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Atg14 PF10186.9 GAX19108.1 - 0.68 9.0 19.8 0.1 11.7 3.9 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 GAX19108.1 - 0.73 9.0 20.0 0.42 9.8 5.1 2.3 2 0 0 2 2 2 0 TMPIT-like protein Herpes_BLRF2 PF05812.12 GAX19108.1 - 0.79 9.9 11.3 0.067 13.3 6.1 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein APG6_N PF17675.1 GAX19108.1 - 8.4 6.9 42.6 0.17 12.4 12.4 3.6 3 1 1 4 4 4 0 Apg6 coiled-coil region DUF4407 PF14362.6 GAX19108.1 - 9.9 5.4 23.4 2.4 7.4 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SHMT PF00464.19 GAX19111.1 - 3.2e-170 566.0 0.0 4e-170 565.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase FliT PF05400.13 GAX19111.1 - 0.009 16.8 4.1 0.053 14.3 0.5 2.9 3 0 0 3 3 3 1 Flagellar protein FliT DUF1297 PF06973.12 GAX19111.1 - 0.086 12.4 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1297) RNA_pol_Rpb1_2 PF00623.20 GAX19112.1 - 1.3e-21 77.6 0.0 1.5e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 GAX19112.1 - 2e-08 34.0 0.1 2.5e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 CX9C PF16860.5 GAX19113.1 - 1.3 9.1 34.2 0.85 9.7 0.4 5.8 5 0 0 5 5 5 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 GAX19114.1 - 0.004 17.2 1.4 1.1 9.5 0.2 3.1 2 1 0 2 2 2 2 CHCH domain CHCH PF06747.13 GAX19115.1 - 0.00013 22.0 4.7 0.033 14.3 1.5 2.7 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 GAX19115.1 - 0.052 13.6 13.1 0.093 12.8 1.5 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, LRR_8 PF13855.6 GAX19118.1 - 5.5e-26 90.1 49.1 2.3e-06 27.3 3.9 7.9 4 3 3 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 GAX19118.1 - 2e-18 66.1 47.2 0.00096 19.5 2.8 9.4 4 2 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX19118.1 - 4.5e-09 35.6 33.3 4.2 8.3 0.0 12.7 13 1 0 13 13 13 3 Leucine Rich Repeat COX5B PF01215.19 GAX19118.1 - 0.093 12.4 0.0 26 4.5 0.0 3.3 2 1 1 3 3 3 0 Cytochrome c oxidase subunit Vb LRR_9 PF14580.6 GAX19118.1 - 1.1 8.8 7.5 3.3 7.2 0.0 3.7 3 1 2 5 5 5 0 Leucine-rich repeat LRR_6 PF13516.6 GAX19118.1 - 1.3 9.3 0.0 1.3 9.3 0.0 9.7 12 0 0 12 12 12 0 Leucine Rich repeat NUP50 PF08911.11 GAX19119.1 - 1.7e-10 41.4 5.8 1.7e-10 41.4 5.8 3.9 4 0 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 GAX19119.1 - 1.7e-05 25.1 0.2 7.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 RanBP1 domain Glyco_hydro_79C PF16862.5 GAX19119.1 - 7.8 7.5 9.4 0.57 11.1 0.1 3.2 3 1 0 3 3 3 0 Glycosyl hydrolase family 79 C-terminal beta domain Bac_globin PF01152.21 GAX19120.1 - 0.0042 17.2 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial-like globin CX9C PF16860.5 GAX19121.1 - 0.002 18.1 0.7 0.002 18.1 0.7 7.8 7 0 0 7 7 7 5 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SAM_decarbox PF01536.16 GAX19122.1 - 1.6e-92 310.3 0.0 2e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase AdoMet_dc PF02675.15 GAX19122.1 - 0.0097 16.1 0.0 0.035 14.4 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine decarboxylase 5_nucleotid PF05761.14 GAX19123.1 - 1.2e-146 489.2 1.6 1.5e-146 489.0 1.6 1.0 1 0 0 1 1 1 1 5' nucleotidase family CheY-binding PF09078.11 GAX19123.1 - 0.039 14.1 0.5 0.085 13.0 0.5 1.5 1 0 0 1 1 1 0 CheY binding PGP_phosphatase PF09419.10 GAX19123.1 - 0.16 11.6 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase LPMO_10 PF03067.15 GAX19124.1 - 1.5e-27 97.5 1.2 2.4e-27 96.9 1.2 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Toxin_7 PF05980.12 GAX19124.1 - 2.2e-06 27.8 26.5 0.0014 18.8 9.2 3.1 2 0 0 2 2 2 2 Toxin 7 Toxin_12 PF07740.12 GAX19124.1 - 0.0021 18.7 7.1 0.0021 18.7 7.1 3.4 3 0 0 3 3 3 2 Ion channel inhibitory toxin ubiquitin PF00240.23 GAX19125.1 - 3e-13 49.3 0.0 5.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX19125.1 - 0.0044 16.8 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Jagunal PF07086.12 GAX19125.1 - 0.051 13.6 0.1 0.092 12.8 0.1 1.4 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis GST_N_2 PF13409.6 GAX19126.1 - 7.9e-10 38.9 0.1 2.9e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX19126.1 - 7.7e-09 35.5 0.1 1.5e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX19126.1 - 1.2e-06 28.9 0.0 3.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAX19126.1 - 1.3e-05 25.3 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAX19126.1 - 0.0016 18.7 0.5 0.044 14.1 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAX19126.1 - 0.0017 18.5 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain eIF2_C PF09173.11 GAX19127.1 - 4.5e-36 123.0 0.1 1.2e-35 121.6 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GAX19127.1 - 7.8e-24 84.3 1.2 6.4e-23 81.3 1.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAX19127.1 - 2.2e-10 40.8 1.3 2.2e-10 40.8 1.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX19127.1 - 0.00077 19.5 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase CxC7 PF18866.1 GAX19127.1 - 0.0033 17.5 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 2 CxC7 like cysteine cluster associated with KDZ transposases RsgA_GTPase PF03193.16 GAX19127.1 - 0.0076 16.2 0.3 0.4 10.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GAX19127.1 - 0.14 12.2 0.1 0.42 10.7 0.1 1.9 1 1 0 1 1 1 0 Dynamin family PduV-EutP PF10662.9 GAX19127.1 - 0.14 11.9 0.3 11 5.8 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Cyclin_N PF00134.23 GAX19128.1 - 2.3e-07 30.6 0.1 5.2e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Grg1 PF11034.8 GAX19128.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.7 3 0 0 3 3 3 0 Glucose-repressible protein Grg1 GTP_EFTU PF00009.27 GAX19129.1 - 6.7e-47 159.6 0.2 1.2e-46 158.8 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX19129.1 - 3e-15 56.0 0.0 6.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX19129.1 - 2.1e-09 37.6 0.0 5.8e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX19129.1 - 0.0001 22.4 0.1 0.00027 21.0 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 GAX19129.1 - 0.0094 16.0 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II FeoB_N PF02421.18 GAX19129.1 - 0.0095 15.5 0.1 0.049 13.2 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 GAX19129.1 - 0.076 13.2 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX19129.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Ribosomal_L10 PF00466.20 GAX19130.1 - 1.5e-21 76.3 0.0 3.1e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 GAX19130.1 - 2.7e-21 75.3 0.3 4.7e-21 74.6 0.3 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 GAX19130.1 - 7.3e-10 39.3 1.7 7.3e-10 39.3 1.7 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein HTH_Tnp_Tc3_1 PF11427.8 GAX19130.1 - 0.022 14.6 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Tc3 transposase Pro_isomerase PF00160.21 GAX19131.1 - 1.2e-08 35.4 0.1 2.4e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FapA PF03961.13 GAX19131.1 - 0.013 14.2 2.1 0.018 13.7 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DNA_pack_N PF02500.15 GAX19131.1 - 0.054 13.3 1.3 0.081 12.7 1.3 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus zf-C4H2 PF10146.9 GAX19131.1 - 0.058 13.7 1.4 0.087 13.1 1.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein CALCOCO1 PF07888.11 GAX19131.1 - 0.11 11.4 8.2 0.15 10.9 8.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 GAX19131.1 - 0.12 12.4 9.1 0.2 11.7 9.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 GAX19131.1 - 0.2 11.4 3.3 0.6 9.9 2.9 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF4446 PF14584.6 GAX19131.1 - 0.24 11.4 2.7 0.28 11.2 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4600 PF15372.6 GAX19131.1 - 0.36 11.3 8.8 0.98 9.9 8.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) UPF0242 PF06785.11 GAX19131.1 - 0.43 10.6 7.3 0.67 10.0 7.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 GAX19131.1 - 0.45 11.0 8.4 0.23 11.9 3.5 2.3 1 1 1 2 2 2 0 Snapin/Pallidin HIP1_clath_bdg PF16515.5 GAX19131.1 - 0.65 10.6 9.7 1.3 9.7 9.7 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 GAX19131.1 - 1.1 9.6 12.6 2.4 8.5 12.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 GAX19131.1 - 2.1 8.4 11.8 12 6.0 5.3 2.2 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Tub PF01167.18 GAX19132.1 - 5.1e-16 59.2 0.0 1.4e-15 57.7 0.0 1.7 1 1 0 1 1 1 1 Tub family GDPD PF03009.17 GAX19133.1 - 9.7e-12 45.2 0.0 5.7e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ribosomal_60s PF00428.19 GAX19134.1 - 8.1e-07 29.6 4.1 1.2e-06 29.0 4.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein MIT PF04212.18 GAX19135.1 - 0.0035 17.4 1.3 0.0046 17.0 0.1 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Baculo_VP91_N PF08475.10 GAX19135.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal RR_TM4-6 PF06459.12 GAX19136.1 - 0.15 11.8 2.4 0.19 11.5 2.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pap_E4 PF02711.14 GAX19136.1 - 0.43 11.6 3.0 0.78 10.7 0.2 2.1 2 0 0 2 2 2 0 E4 protein EF-hand_7 PF13499.6 GAX19137.1 - 4e-08 33.6 2.9 0.0034 17.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX19137.1 - 9.9e-07 27.9 5.6 0.00011 21.5 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAX19137.1 - 1.6e-06 27.3 1.5 0.00074 18.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX19137.1 - 2.2e-06 27.2 1.6 0.0049 16.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAX19137.1 - 0.00038 20.2 2.2 0.02 14.7 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair DUF1664 PF07889.12 GAX19137.1 - 0.03 14.4 1.1 0.05 13.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 GAX19137.1 - 0.58 8.7 2.9 0.84 8.2 2.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4897 PF16238.5 GAX19137.1 - 1.5 8.6 7.1 1.1 9.1 5.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4897) Endonuc_Holl PF10107.9 GAX19137.1 - 1.6 8.6 4.3 3.1 7.7 4.3 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Cor1 PF04803.12 GAX19137.1 - 4.8 7.4 16.6 1.3 9.2 12.9 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region UPF0449 PF15136.6 GAX19137.1 - 9.4 6.8 9.4 1.5 9.3 5.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Ank_4 PF13637.6 GAX19139.1 - 1.8e-10 41.2 0.0 3.2e-05 24.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX19139.1 - 1e-06 29.2 0.0 2.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX19139.1 - 4e-05 23.8 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19139.1 - 6.1e-05 23.1 0.0 0.063 13.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAX19139.1 - 0.00043 20.6 0.0 1.7 9.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GAX19140.1 - 8.5e-05 23.1 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX19140.1 - 0.063 13.9 0.1 7.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 GAX19140.1 - 0.18 12.4 0.1 1.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) YL1 PF05764.13 GAX19140.1 - 1 9.4 8.6 2.7 8.1 8.6 1.6 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GAX19140.1 - 3.7 6.8 11.3 5.5 6.2 11.3 1.2 1 0 0 1 1 1 0 BUD22 FMN_dh PF01070.18 GAX19141.1 - 8.8e-119 396.6 0.0 1.1e-118 396.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 GAX19141.1 - 6.2e-06 25.4 0.8 1.2e-05 24.5 0.8 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 GAX19141.1 - 1.9e-05 24.0 0.1 3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 GAX19141.1 - 0.00099 18.6 0.2 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 GAX19141.1 - 0.011 15.1 0.3 0.081 12.2 0.2 2.0 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAX19141.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 GAX19141.1 - 0.068 12.4 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF1485 PF07364.12 GAX19141.1 - 0.21 10.8 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M81 DAO PF01266.24 GAX19142.1 - 1.9e-49 169.1 0.2 2.3e-49 168.9 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX19142.1 - 3e-06 26.6 1.6 0.00014 21.1 1.2 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAX19142.1 - 1.6e-05 24.3 0.4 0.0014 18.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX19142.1 - 0.00085 19.5 0.6 0.0019 18.4 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX19142.1 - 0.0019 17.5 1.4 0.0022 17.3 0.4 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 GAX19142.1 - 0.0019 18.2 0.8 0.33 10.9 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAX19142.1 - 0.0023 18.4 1.0 0.017 15.7 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX19142.1 - 0.0029 16.8 1.7 0.23 10.5 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAX19142.1 - 0.0031 16.8 1.2 0.66 9.2 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 GAX19142.1 - 0.014 14.4 1.0 0.39 9.7 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 GAX19142.1 - 0.051 12.4 0.8 1.4 7.7 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase IlvN PF07991.12 GAX19142.1 - 0.11 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HI0933_like PF03486.14 GAX19142.1 - 0.15 10.7 4.2 0.26 9.9 1.6 2.0 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 GAX19142.1 - 0.15 11.9 0.8 0.36 10.7 0.8 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 GAX19142.1 - 0.84 8.9 3.5 1.4 8.2 0.7 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pho88 PF10032.9 GAX19144.1 - 1.1e-25 90.0 0.1 1.6e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ank_2 PF12796.7 GAX19144.1 - 6.7e-10 39.4 0.1 9.9e-08 32.5 0.0 2.8 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19144.1 - 1.2e-06 28.9 0.1 0.0019 18.7 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX19144.1 - 7.1e-05 23.0 0.0 0.0016 18.7 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19144.1 - 0.00012 22.2 0.0 1.8 9.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAX19144.1 - 0.00036 20.8 0.5 0.82 10.2 0.0 3.9 5 0 0 5 5 5 2 Ankyrin repeat Aminotran_1_2 PF00155.21 GAX19145.1 - 2.1e-44 152.2 0.0 3.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAX19145.1 - 0.0099 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase PNK3P PF08645.11 GAX19146.1 - 2.1e-22 79.5 0.0 4.6e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 GAX19146.1 - 3.8e-17 62.8 0.2 3.7e-16 59.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX19146.1 - 0.00011 22.8 2.5 0.00052 20.6 0.2 2.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX19146.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 GAX19146.1 - 0.0002 21.6 0.0 0.00078 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAX19146.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 GAX19146.1 - 0.019 14.7 0.2 0.076 12.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain tRNA_lig_kinase PF08303.11 GAX19146.1 - 0.022 14.9 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain VirE PF05272.11 GAX19146.1 - 0.032 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_25 PF13481.6 GAX19146.1 - 0.038 13.6 0.1 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX19146.1 - 0.04 13.3 0.1 0.42 9.9 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 GAX19146.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_14 PF13173.6 GAX19146.1 - 0.12 12.4 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Oxidored_FMN PF00724.20 GAX19147.1 - 1.2e-75 254.9 0.0 1.4e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ubiquitin PF00240.23 GAX19147.1 - 0.051 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family TGT PF01702.18 GAX19148.1 - 2e-121 405.4 0.0 2.6e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pirin PF02678.16 GAX19149.1 - 5.3e-23 81.1 0.2 5e-20 71.5 0.0 2.3 2 0 0 2 2 2 2 Pirin Pirin_C PF05726.13 GAX19149.1 - 1.6e-16 60.5 0.0 2.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain COX7a PF02238.15 GAX19150.1 - 0.027 14.9 0.1 0.04 14.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII 2-oxoacid_dh PF00198.23 GAX19151.1 - 1.8e-78 263.2 0.1 2.3e-78 262.8 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX19151.1 - 6e-16 58.0 3.5 1.1e-15 57.2 3.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAX19151.1 - 0.027 14.3 0.7 0.027 14.3 0.7 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 GAX19151.1 - 0.032 14.9 3.2 1.7 9.4 0.2 2.5 1 1 1 2 2 2 0 HlyD family secretion protein Ndc1_Nup PF09531.10 GAX19151.1 - 0.79 8.3 1.8 0.96 8.1 1.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup OTCace PF00185.24 GAX19152.1 - 4.7e-56 189.2 0.4 6.1e-54 182.3 0.1 2.4 3 0 0 3 3 3 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 GAX19152.1 - 7.2e-46 155.9 0.0 1.7e-45 154.6 0.0 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DnaJ PF00226.31 GAX19153.1 - 1.8e-05 24.8 0.7 4.7e-05 23.4 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain tRNA_bind PF01588.20 GAX19154.1 - 1.3e-26 92.5 0.0 3.4e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain PHD PF00628.29 GAX19155.1 - 1.1e-16 60.4 19.4 1.2e-09 37.9 8.6 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 GAX19155.1 - 0.00011 21.7 14.1 0.0015 18.0 4.3 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING_2 PF13639.6 GAX19155.1 - 0.0012 19.1 8.7 0.0012 19.1 8.7 3.2 3 0 0 3 3 3 1 Ring finger domain C1_1 PF00130.22 GAX19155.1 - 0.13 12.2 0.2 0.13 12.2 0.2 3.3 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 GAX19155.1 - 1.2 9.5 9.7 2.3 8.6 2.4 2.7 2 0 0 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.6 GAX19155.1 - 2.5 8.4 14.8 0.092 13.0 2.6 3.0 2 1 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 GAX19155.1 - 6.3 6.8 14.4 12 5.9 0.3 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L27A PF00828.19 GAX19156.1 - 2.8e-26 92.7 0.1 4e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 GAX19156.1 - 0.011 15.2 0.1 0.034 13.6 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein 60S L18 and 50S L18e MORN PF02493.20 GAX19157.1 - 5.3e-27 92.1 49.0 6.3e-07 28.9 0.9 8.8 7 1 0 7 7 7 7 MORN repeat RDD PF06271.12 GAX19159.1 - 8.2e-11 42.3 2.5 1.1e-10 41.9 2.5 1.2 1 0 0 1 1 1 1 RDD family Dzip-like_N PF13815.6 GAX19159.1 - 0.38 10.7 1.8 0.61 10.1 1.8 1.3 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Bac_globin PF01152.21 GAX19160.1 - 7.7e-10 39.0 0.5 2.2e-09 37.5 0.5 1.7 1 1 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 GAX19160.1 - 0.0037 17.2 0.0 0.0064 16.4 0.0 1.6 1 1 0 1 1 1 1 Protoglobin Acetyltransf_19 PF18015.1 GAX19160.1 - 0.021 15.0 0.1 0.05 13.8 0.1 1.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.6 GAX19162.1 - 3.3e-12 46.5 6.5 6.8e-12 45.5 6.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX19162.1 - 6e-12 45.1 2.3 1.5e-11 43.8 2.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX19162.1 - 2.7e-06 27.2 3.9 6e-06 26.0 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX19162.1 - 2e-05 24.3 7.0 0.00012 21.8 7.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX19162.1 - 5.1e-05 23.5 7.6 0.00031 21.0 7.6 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX19162.1 - 8.9e-05 22.4 4.6 0.00023 21.0 4.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX19162.1 - 0.00012 22.0 2.5 0.00012 22.0 2.5 1.8 2 0 0 2 2 1 1 RING-type zinc-finger FANCL_C PF11793.8 GAX19162.1 - 0.0032 17.6 5.1 0.0092 16.1 5.1 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAX19162.1 - 0.031 14.1 5.2 0.06 13.2 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX19162.1 - 0.05 13.5 7.4 0.12 12.2 7.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 GAX19162.1 - 0.11 12.6 0.7 0.27 11.4 0.7 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-ANAPC11 PF12861.7 GAX19162.1 - 0.14 12.2 10.5 1.9 8.6 10.2 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX19162.1 - 0.17 11.5 5.4 0.45 10.2 5.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 GAX19162.1 - 0.7 10.1 4.2 2.1 8.6 4.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAX19162.1 - 4 7.4 6.5 9.7 6.2 5.2 2.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DUF89 PF01937.19 GAX19164.1 - 2.8e-79 266.7 0.3 3.2e-79 266.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF1155 PF06633.11 GAX19164.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) MCD PF05292.11 GAX19165.1 - 5.2e-65 219.6 0.0 1.9e-64 217.7 0.0 1.9 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain XH PF03469.14 GAX19165.1 - 0.035 14.0 0.4 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 XH domain MCD_N PF17408.2 GAX19165.1 - 0.07 13.3 0.7 0.36 11.0 0.3 2.4 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain MAGSP PF03082.14 GAX19166.1 - 0.076 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein Glyco_transf_8 PF01501.20 GAX19167.1 - 1.8e-05 24.4 0.2 0.0092 15.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 8 Amino_oxidase PF01593.24 GAX19168.1 - 8.7e-12 45.1 0.1 2.9e-10 40.1 0.0 2.9 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX19168.1 - 1e-08 35.3 0.2 2.8e-08 33.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX19168.1 - 6.6e-05 22.3 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 GAX19168.1 - 0.0062 15.8 0.3 0.012 14.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAX19168.1 - 0.0088 15.7 0.2 0.21 11.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX19168.1 - 0.017 14.2 0.2 0.047 12.8 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 GAX19168.1 - 0.18 11.1 0.2 0.29 10.5 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase bZIP_2 PF07716.15 GAX19169.1 - 0.86 9.7 14.8 2.8 8.1 14.8 1.9 1 0 0 1 1 1 0 Basic region leucine zipper CRAL_TRIO_2 PF13716.6 GAX19170.1 - 0.0028 17.8 1.5 0.82 9.8 0.0 3.0 3 0 0 3 3 3 2 Divergent CRAL/TRIO domain Abhydrolase_1 PF00561.20 GAX19172.1 - 1.2e-31 110.3 0.2 3.2e-30 105.6 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX19172.1 - 0.00064 20.4 0.1 0.0014 19.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 GAX19172.1 - 0.00097 19.2 0.0 0.0031 17.6 0.0 1.9 1 0 0 1 1 1 1 TAP-like protein AAA_2 PF07724.14 GAX19174.1 - 3.2e-48 164.1 0.0 1.4e-41 142.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAX19174.1 - 3.3e-28 98.7 0.0 6.6e-14 52.5 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_9 PF17871.1 GAX19174.1 - 2e-24 85.5 0.0 5.4e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 GAX19174.1 - 1.4e-17 64.0 0.0 2e-11 44.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX19174.1 - 1.5e-11 44.9 11.0 3.7e-07 30.7 0.1 5.8 5 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 GAX19174.1 - 3.1e-11 43.7 2.7 2.1e-05 24.8 0.2 4.9 3 2 0 3 3 3 2 AAA domain ClpB_D2-small PF10431.9 GAX19174.1 - 9.2e-11 41.6 0.1 3.6e-10 39.8 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 GAX19174.1 - 6.4e-10 39.0 0.0 1e-06 28.6 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 GAX19174.1 - 2.2e-08 33.7 0.2 0.031 13.7 0.2 3.7 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX19174.1 - 2.8e-07 30.2 0.0 0.016 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAX19174.1 - 1.1e-06 28.5 0.0 0.0092 15.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 GAX19174.1 - 2.7e-06 26.9 0.0 0.034 13.5 0.0 3.8 3 1 0 3 3 2 1 Bacterial TniB protein RuvB_N PF05496.12 GAX19174.1 - 2.7e-05 24.0 0.0 1.9 8.2 0.0 4.6 5 0 0 5 5 5 1 Holliday junction DNA helicase RuvB P-loop domain Torsin PF06309.11 GAX19174.1 - 8.2e-05 22.7 0.0 0.00057 20.0 0.0 2.3 2 0 0 2 2 2 1 Torsin ResIII PF04851.15 GAX19174.1 - 0.0001 22.3 0.0 0.14 12.2 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 GAX19174.1 - 0.00011 22.8 0.2 0.82 10.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 GAX19174.1 - 0.00027 21.3 0.0 0.48 10.8 0.0 3.1 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 GAX19174.1 - 0.00031 20.7 0.0 0.54 10.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 GAX19174.1 - 0.00046 20.0 0.2 1.9 8.2 0.0 3.9 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.6 GAX19174.1 - 0.00048 20.2 0.0 0.1 12.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 GAX19174.1 - 0.00049 20.0 0.4 0.21 11.4 0.1 3.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAX19174.1 - 0.00064 19.9 0.0 0.67 10.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAX19174.1 - 0.00068 20.0 1.6 0.039 14.3 0.0 3.6 4 1 0 4 4 2 1 AAA domain AAA_24 PF13479.6 GAX19174.1 - 0.0011 18.7 0.0 0.7 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 GAX19174.1 - 0.0019 17.4 0.0 0.56 9.3 0.0 2.9 2 1 0 2 2 2 1 MCM P-loop domain PhoH PF02562.16 GAX19174.1 - 0.0025 17.3 0.0 0.8 9.1 0.0 2.8 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.12 GAX19174.1 - 0.0036 17.3 0.1 0.37 10.7 0.0 3.1 3 0 0 3 3 2 1 NACHT domain T2SSE PF00437.20 GAX19174.1 - 0.0036 16.4 0.0 0.066 12.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 GAX19174.1 - 0.0042 16.7 0.1 6.1 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 GAX19174.1 - 0.0088 15.3 0.0 1.6 8.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 GAX19174.1 - 0.011 16.0 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 GAX19174.1 - 0.012 14.8 0.0 0.31 10.2 0.0 2.8 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_28 PF13521.6 GAX19174.1 - 0.012 15.8 0.1 3.2 8.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAX19174.1 - 0.015 15.8 0.0 1.9 9.0 0.0 2.9 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.13 GAX19174.1 - 0.018 14.2 0.2 2.8 7.0 0.0 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 GAX19174.1 - 0.026 14.2 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 GAX19174.1 - 0.029 13.5 0.1 7.3 5.6 0.0 3.0 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 GAX19174.1 - 0.048 14.2 0.0 16 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAX19174.1 - 0.057 13.0 0.2 3 7.4 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain phage_tail_N PF08400.10 GAX19174.1 - 0.11 12.5 0.6 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Prophage tail fibre N-terminal DNA_pol3_delta2 PF13177.6 GAX19174.1 - 0.12 12.2 0.0 8 6.2 0.0 3.0 4 0 0 4 4 2 0 DNA polymerase III, delta subunit Clp_N PF02861.20 GAX19174.1 - 0.12 12.5 0.1 11 6.3 0.2 2.8 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component ATPase PF06745.13 GAX19174.1 - 0.13 11.6 0.0 9.2 5.5 0.0 2.9 3 0 0 3 3 3 0 KaiC NTPase_1 PF03266.15 GAX19174.1 - 0.13 12.2 0.2 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 NTPase DEAD PF00270.29 GAX19174.1 - 0.2 11.4 0.6 35 4.1 0.1 3.1 2 2 0 2 2 2 0 DEAD/DEAH box helicase DUF1765 PF08578.10 GAX19175.1 - 0.13 12.8 0.1 0.21 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) SporV_AA PF12164.8 GAX19177.1 - 0.15 12.4 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Stage V sporulation protein AA TTSSLRR PF12468.8 GAX19177.1 - 0.73 10.1 17.9 0.72 10.1 5.0 3.5 3 0 0 3 3 3 0 Type III secretion system leucine rich repeat protein Molybdopterin_N PF18364.1 GAX19178.1 - 0.0044 17.0 0.4 0.48 10.5 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin oxidoreductase N-terminal domain NMU PF02070.15 GAX19178.1 - 0.16 11.9 0.1 17 5.4 0.1 2.8 2 0 0 2 2 2 0 Neuromedin U ExbD PF02472.16 GAX19178.1 - 0.18 12.0 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR zf_CCCH_5 PF18384.1 GAX19179.1 - 0.13 12.4 0.0 7.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) Myotub-related PF06602.14 GAX19182.1 - 3.8e-109 364.8 0.2 4.9e-109 364.5 0.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 GAX19182.1 - 0.0015 18.5 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAX19182.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MGAT2 PF05060.14 GAX19183.1 - 1e-32 113.6 0.4 6.3e-30 104.4 0.4 2.7 1 1 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) GST_C PF00043.25 GAX19184.1 - 3.1e-13 49.8 0.2 4.9e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX19184.1 - 1.3e-05 25.1 0.0 3.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX19184.1 - 2.5e-05 24.4 0.0 4.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 GAX19184.1 - 0.0013 19.0 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX19184.1 - 0.026 14.9 0.0 0.059 13.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAX19184.1 - 0.058 13.2 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAX19184.1 - 0.084 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 GAX19184.1 - 0.16 12.4 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.19 GAX19185.1 - 2.2e-15 57.0 8.3 2.8e-15 56.6 8.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein GHMP_kinases_N PF00288.26 GAX19185.1 - 0.013 15.7 3.6 0.013 15.7 3.6 2.0 2 0 0 2 2 2 0 GHMP kinases N terminal domain Ank_5 PF13857.6 GAX19186.1 - 6.2e-12 45.5 0.1 1.1e-06 28.8 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX19186.1 - 8.3e-12 45.5 0.0 2.3e-05 24.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19186.1 - 1.4e-06 28.7 0.1 0.0019 18.7 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX19186.1 - 4.2e-06 27.0 0.1 0.056 13.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAX19186.1 - 0.00044 20.5 0.7 3.3 8.6 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Spectrin PF00435.21 GAX19186.1 - 0.39 11.2 19.8 0.11 13.0 2.0 3.2 1 1 2 3 3 3 0 Spectrin repeat BNIP2 PF12496.8 GAX19186.1 - 0.88 10.0 6.9 0.24 11.8 0.3 2.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ADP_ribosyl_GH PF03747.14 GAX19187.1 - 5e-33 115.1 0.1 1.2e-32 113.8 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase HCV_NS5a_C PF12941.7 GAX19187.1 - 0.016 15.0 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Methyltransf_23 PF13489.6 GAX19190.1 - 2e-07 31.0 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX19190.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAX19190.1 - 0.0068 16.2 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 GAX19190.1 - 0.0089 16.7 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX19190.1 - 0.049 13.4 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAX19190.1 - 0.11 13.2 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX19190.1 - 0.14 13.0 0.0 0.67 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain ACC_epsilon PF13822.6 GAX19191.1 - 0.027 15.1 1.7 0.046 14.4 1.7 1.3 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit LCAT PF02450.15 GAX19192.1 - 2.5e-71 240.9 0.0 3.7e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Guanylate_cyc PF00211.20 GAX19193.1 - 8.5e-23 80.9 0.0 1.3e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_12 PF13424.6 GAX19194.1 - 2.7e-05 24.3 13.8 0.012 15.8 0.6 4.5 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX19194.1 - 0.037 14.8 16.0 0.27 12.2 0.4 5.0 2 2 2 5 5 5 0 Tetratricopeptide repeat Cep57_CLD_2 PF14197.6 GAX19194.1 - 0.11 12.6 1.5 0.3 11.2 1.5 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TPR_2 PF07719.17 GAX19194.1 - 0.2 11.9 9.9 0.75 10.1 0.4 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX19194.1 - 0.36 10.7 3.2 4.4 7.3 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX19194.1 - 0.37 10.9 6.7 4.5 7.5 0.4 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 GAX19194.1 - 0.62 9.4 6.8 1.4 8.3 0.1 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 GAX19194.1 - 10 6.2 8.0 21 5.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Epimerase PF01370.21 GAX19195.1 - 8.9e-19 67.9 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX19195.1 - 4.3e-15 55.5 0.0 5.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX19195.1 - 6.7e-09 35.3 0.0 1.1e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAX19195.1 - 5.2e-07 29.7 0.0 1.6e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAX19195.1 - 4.3e-06 26.4 0.0 5.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 GAX19195.1 - 0.04 13.8 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 GAX19196.1 - 1.8e-23 83.4 0.0 2.5e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX19196.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-RING_2 PF13639.6 GAX19197.1 - 3.6e-09 36.8 8.4 7.5e-09 35.8 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAX19197.1 - 3.3e-08 33.3 4.9 6.2e-08 32.4 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX19197.1 - 7e-07 29.1 5.8 1.7e-06 27.8 5.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX19197.1 - 1.1e-06 28.5 3.8 1.1e-06 28.5 3.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX19197.1 - 1.4e-06 28.0 6.2 2.8e-06 27.1 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX19197.1 - 1.6e-06 27.9 8.8 4.6e-06 26.4 8.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX19197.1 - 7.8e-06 25.7 7.4 0.00024 20.9 2.0 2.6 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX19197.1 - 7e-05 22.8 3.7 0.00026 21.0 3.7 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAX19197.1 - 0.00019 21.1 5.4 0.0014 18.4 5.5 2.2 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GAX19197.1 - 0.00048 20.4 7.4 0.0018 18.5 7.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 GAX19197.1 - 0.011 15.8 7.1 0.011 15.8 7.1 2.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 GAX19197.1 - 0.2 11.6 2.5 0.39 10.7 2.5 1.5 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 GAX19197.1 - 0.37 10.8 4.6 0.97 9.5 4.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon Rad10 PF03834.14 GAX19198.1 - 2.9e-42 143.3 0.1 5.1e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.7 GAX19198.1 - 0.00018 21.6 0.0 0.00039 20.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GAX19198.1 - 0.041 14.5 0.0 0.16 12.6 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain CDK2AP PF09806.9 GAX19198.1 - 0.75 9.8 7.0 0.052 13.6 1.2 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Hydin_ADK PF17213.3 GAX19198.1 - 6.9 6.9 8.2 0.62 10.3 2.2 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DENN PF02141.21 GAX19199.1 - 1.5e-22 80.4 1.0 3.8e-22 79.1 1.0 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain PDZ PF00595.24 GAX19199.1 - 1.2e-06 28.8 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain dbPDZ_assoc PF16610.5 GAX19199.1 - 0.037 14.3 3.0 0.16 12.2 3.0 2.1 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Pkinase PF00069.25 GAX19200.1 - 9.5e-50 169.4 0.0 1.2e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19200.1 - 6.2e-23 81.4 0.0 9.1e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX19200.1 - 4.9e-05 22.8 0.0 7.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX19200.1 - 0.0015 18.5 0.1 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX19200.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 GAX19200.1 - 0.097 12.0 0.0 2.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 GAX19200.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Glyco_trans_2_3 PF13632.6 GAX19201.1 - 6.5e-17 62.1 1.2 6.5e-17 62.1 1.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 SIR2 PF02146.17 GAX19202.1 - 1.8e-12 47.6 0.4 9.5e-10 38.7 0.4 2.6 1 1 0 1 1 1 1 Sir2 family MscS_porin PF12795.7 GAX19202.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Motile_Sperm PF00635.26 GAX19204.1 - 9.3e-15 54.4 0.0 3.8e-14 52.5 0.0 2.0 2 1 0 2 2 2 1 MSP (Major sperm protein) domain DUF4407 PF14362.6 GAX19204.1 - 0.029 13.7 0.2 0.035 13.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 GAX19204.1 - 0.1 11.5 2.7 0.13 11.2 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4265 PF14085.6 GAX19204.1 - 0.13 12.2 0.0 1.8 8.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4265) DNA_ligase_A_M PF01068.21 GAX19205.1 - 0.028 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Methyltransf_31 PF13847.6 GAX19208.1 - 2.7e-29 101.9 0.0 4.1e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX19208.1 - 1.5e-17 64.1 0.1 3.2e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX19208.1 - 1.6e-15 57.5 0.1 4.2e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX19208.1 - 6.6e-13 48.8 0.0 9.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX19208.1 - 2.2e-12 47.6 0.1 5.7e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX19208.1 - 2.7e-11 43.2 0.0 4.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 GAX19208.1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX19208.1 - 0.00013 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAX19208.1 - 0.00087 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.26 GAX19208.1 - 0.0011 19.0 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMAS PF02353.20 GAX19208.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 GAX19208.1 - 0.016 15.4 0.0 0.058 13.5 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 GAX19208.1 - 0.03 13.2 0.0 0.1 11.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 GAX19208.1 - 0.042 13.8 0.5 0.07 13.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 GAX19208.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 GAX19208.1 - 0.19 11.5 0.4 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase ADK_lid PF05191.14 GAX19208.1 - 0.27 11.2 2.2 0.83 9.7 2.2 1.9 1 0 0 1 1 1 0 Adenylate kinase, active site lid Fer2 PF00111.27 GAX19209.1 - 5.3e-08 32.7 0.5 4.9e-06 26.4 0.2 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 GAX19209.1 - 0.04 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ank_2 PF12796.7 GAX19210.1 - 9.5e-06 26.1 0.0 2.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX19210.1 - 1.9e-05 24.8 0.0 5.6e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX19210.1 - 0.036 14.7 0.0 0.19 12.4 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DEDD_Tnp_IS110 PF01548.17 GAX19210.1 - 0.11 12.3 4.7 0.19 11.6 0.0 3.2 3 1 0 3 3 3 0 Transposase CALCOCO1 PF07888.11 GAX19210.1 - 0.9 8.3 44.6 0.013 14.4 25.3 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF16 PF01519.16 GAX19210.1 - 3.1 8.3 27.1 0.22 12.0 2.6 4.6 2 1 3 5 5 5 0 Protein of unknown function DUF16 Spc7 PF08317.11 GAX19210.1 - 7.3 5.4 44.8 0.52 9.1 4.1 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein Homez PF11569.8 GAX19211.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Ank_5 PF13857.6 GAX19212.1 - 1.1e-05 25.7 0.1 8.7e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX19212.1 - 0.098 13.3 0.1 4.3 8.0 0.2 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19212.1 - 0.15 12.7 0.4 6.2 7.7 0.1 2.9 2 0 0 2 2 2 0 Ankyrin repeat Borealin PF10512.9 GAX19212.1 - 4.4 7.3 9.6 4.7 7.2 0.9 3.9 3 0 0 3 3 3 0 Cell division cycle-associated protein 8 Ank_5 PF13857.6 GAX19215.1 - 9.5e-06 25.8 0.0 0.00054 20.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX19215.1 - 0.0014 19.1 0.0 0.0037 17.8 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX19215.1 - 0.0015 18.8 0.0 3.3 8.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF1819 PF08849.11 GAX19215.1 - 0.16 11.8 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Maf1 PF09174.10 GAX19216.1 - 6.1e-33 114.4 0.0 4.7e-25 88.7 0.0 2.3 2 1 0 2 2 2 2 Maf1 regulator Gal-bind_lectin PF00337.22 GAX19217.1 - 8.6e-07 28.6 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin RRM_1 PF00076.22 GAX19217.1 - 0.0018 18.1 0.0 0.0051 16.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Utp14 PF04615.13 GAX19217.1 - 0.092 11.3 22.8 0.14 10.7 22.8 1.2 1 0 0 1 1 1 0 Utp14 protein NOA36 PF06524.12 GAX19217.1 - 0.34 10.2 9.8 0.61 9.4 9.8 1.4 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 GAX19217.1 - 0.39 10.6 9.0 0.59 10.0 9.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region SWIRM-assoc_2 PF16496.5 GAX19217.1 - 8.9 5.1 19.7 15 4.3 19.7 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Kinesin PF00225.23 GAX19218.1 - 2e-77 260.4 0.2 2e-77 260.4 0.2 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAX19218.1 - 4.6e-14 52.6 2.1 7.6e-14 51.9 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding bZIP_1 PF00170.21 GAX19218.1 - 0.0007 19.6 3.8 0.0007 19.6 3.8 4.8 5 1 1 6 6 4 1 bZIP transcription factor ZapB PF06005.12 GAX19218.1 - 0.0014 19.0 4.1 0.0014 19.0 4.1 3.4 2 2 0 2 2 2 1 Cell division protein ZapB DUF4363 PF14276.6 GAX19218.1 - 0.01 16.0 8.0 0.01 15.9 5.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4363) FlxA PF14282.6 GAX19218.1 - 0.1 12.6 18.9 1 9.4 11.4 3.0 2 0 0 2 2 2 0 FlxA-like protein ADIP PF11559.8 GAX19218.1 - 0.19 11.8 29.6 0.02 15.0 9.5 3.5 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 GAX19218.1 - 0.32 11.1 8.3 1.1 9.3 1.5 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 GAX19218.1 - 0.37 10.6 15.2 0.021 14.6 3.9 3.1 2 1 1 3 3 3 0 Septum formation initiator TcpS PF17456.2 GAX19218.1 - 0.39 10.8 10.5 3.9 7.5 4.4 3.3 2 1 0 3 3 3 0 Toxin-coregulated pilus protein S HALZ PF02183.18 GAX19218.1 - 0.49 10.6 3.9 0.62 10.3 0.8 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper TSC22 PF01166.18 GAX19218.1 - 0.54 10.6 11.8 1.9 8.8 0.7 4.0 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF4709 PF15821.5 GAX19218.1 - 0.67 10.3 14.5 0.18 12.1 2.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) DUF641 PF04859.12 GAX19218.1 - 1.2 9.5 19.8 4.2 7.7 7.2 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Apolipoprotein PF01442.18 GAX19218.1 - 1.5 8.6 18.7 6.3 6.6 18.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain dCache_2 PF08269.11 GAX19218.1 - 3.1 6.9 11.1 0.51 9.5 6.4 1.9 1 1 0 2 2 2 0 Cache domain DUF3450 PF11932.8 GAX19218.1 - 3.6 6.8 25.8 1.7 7.9 11.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 GAX19218.1 - 3.8 7.9 25.0 1.2 9.6 7.3 4.7 2 1 2 4 4 4 0 Csm1 N-terminal domain DUF883 PF05957.13 GAX19218.1 - 4.1 8.1 12.7 0.58 10.8 2.5 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) TolA_bind_tri PF16331.5 GAX19218.1 - 5.7 7.1 21.4 4 7.6 9.5 3.0 2 2 0 2 2 2 0 TolA binding protein trimerisation WXG100 PF06013.12 GAX19218.1 - 9.2 6.6 10.6 0.23 11.7 2.3 2.6 3 1 1 4 4 3 0 Proteins of 100 residues with WXG Spc7 PF08317.11 GAX19218.1 - 9.8 4.9 28.4 0.7 8.7 12.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-RING_2 PF13639.6 GAX19219.1 - 1.6e-10 41.1 3.9 3.4e-10 40.1 3.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX19219.1 - 9.9e-07 29.0 4.5 2.7e-06 27.6 4.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX19219.1 - 3.7e-06 26.7 3.2 3.7e-06 26.7 3.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX19219.1 - 5e-06 26.1 1.1 1.3e-05 24.8 1.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX19219.1 - 3.1e-05 23.8 2.5 7.5e-05 22.5 2.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX19219.1 - 0.00023 21.1 0.7 0.00061 19.8 0.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX19219.1 - 0.0014 18.5 1.5 0.0014 18.5 1.5 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX19219.1 - 0.002 18.1 2.8 0.002 18.1 2.8 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAX19219.1 - 0.0034 17.5 4.0 0.0089 16.2 4.0 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAX19219.1 - 0.0044 16.9 1.9 0.0044 16.9 1.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 GAX19219.1 - 0.031 14.3 4.8 0.087 12.9 4.8 1.8 1 1 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 GAX19219.1 - 0.038 13.6 5.2 0.097 12.3 5.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FBP_C PF16571.5 GAX19219.1 - 0.065 12.8 0.2 0.15 11.6 0.2 1.6 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger zf-RING-like PF08746.11 GAX19219.1 - 0.45 10.9 3.6 1.4 9.3 3.6 1.8 1 0 0 1 1 1 0 RING-like domain Aldo_ket_red PF00248.21 GAX19220.1 - 4.4e-73 246.1 0.0 5.1e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SAM_LFY PF01698.16 GAX19220.1 - 0.094 12.7 0.0 8.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain PH PF00169.29 GAX19221.1 - 3.5e-17 62.8 0.1 7.4e-07 29.6 0.0 3.8 3 1 1 4 4 4 2 PH domain PH_9 PF15410.6 GAX19221.1 - 0.028 14.8 0.2 8.4 6.8 0.0 3.5 3 0 0 3 3 3 0 Pleckstrin homology domain AAA_28 PF13521.6 GAX19223.1 - 4.2e-27 95.4 0.0 6.7e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Pestivirus_E2 PF16329.5 GAX19223.1 - 0.021 13.7 0.0 0.044 12.6 0.0 1.4 2 0 0 2 2 2 0 Pestivirus envelope glycoprotein E2 NTPase_1 PF03266.15 GAX19223.1 - 0.046 13.6 0.0 0.29 11.0 0.0 2.2 1 1 0 1 1 1 0 NTPase AAA_33 PF13671.6 GAX19223.1 - 0.14 12.4 0.1 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3275 PF11679.8 GAX19225.1 - 0.16 12.0 1.2 0.16 12.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DapH_N PF08503.10 GAX19225.1 - 8.1 6.7 8.0 2e+02 2.3 7.2 2.7 1 1 1 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal Aldo_ket_red PF00248.21 GAX19226.1 - 1.7e-15 57.0 0.0 2.9e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family PolyA_pol PF01743.20 GAX19227.1 - 7.9e-26 90.9 0.1 2.7e-21 76.3 0.1 2.5 1 1 1 2 2 2 2 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAX19227.1 - 7e-05 22.5 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A TRAM_LAG1_CLN8 PF03798.16 GAX19228.1 - 2e-06 27.7 19.6 2.3e-06 27.5 19.6 1.1 1 0 0 1 1 1 1 TLC domain YL1 PF05764.13 GAX19229.1 - 0.00066 19.9 2.1 0.00077 19.7 2.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SpaA PF17802.1 GAX19229.1 - 0.0084 16.4 0.8 0.011 16.0 0.8 1.2 1 0 0 1 1 1 1 Prealbumin-like fold domain IFT57 PF10498.9 GAX19229.1 - 0.026 13.5 1.8 0.029 13.3 1.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Arm PF00514.23 GAX19230.1 - 9e-41 136.7 13.3 2.9e-10 39.8 0.3 7.3 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAX19230.1 - 6.4e-14 52.1 6.2 9.1e-07 29.3 0.0 5.2 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 GAX19230.1 - 2.2e-09 37.6 4.1 0.00065 20.0 0.1 4.3 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.22 GAX19230.1 - 1.1e-06 28.4 5.0 0.2 12.0 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.20 GAX19230.1 - 0.00028 19.6 1.3 0.023 13.3 1.4 3.1 1 1 0 1 1 1 1 Adaptin N terminal region Atx10homo_assoc PF09759.9 GAX19230.1 - 0.0027 17.7 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm_3 PF16186.5 GAX19230.1 - 0.01 15.4 1.8 0.026 14.1 1.8 1.6 1 0 0 1 1 1 1 Atypical Arm repeat Tubulin PF00091.25 GAX19231.1 - 5.7e-68 229.0 0.0 1.3e-67 227.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAX19231.1 - 7.6e-43 145.7 0.0 1.6e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAX19231.1 - 9e-05 22.8 0.0 0.028 14.7 0.0 2.4 2 0 0 2 2 2 2 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GAX19231.1 - 0.0086 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin like WD40 PF00400.32 GAX19233.1 - 4.4e-09 36.8 6.0 0.17 12.8 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.6 GAX19233.1 - 0.012 16.0 4.5 0.38 11.3 0.1 4.4 4 1 1 5 5 5 0 PQQ-like domain WD40_like PF17005.5 GAX19233.1 - 0.015 14.6 0.1 0.26 10.6 0.1 2.2 1 1 0 2 2 2 0 WD40-like domain BBS2_Mid PF14783.6 GAX19233.1 - 0.099 12.7 0.0 12 6.0 0.0 2.9 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region TRAM_LAG1_CLN8 PF03798.16 GAX19234.1 - 8.7e-11 41.9 23.1 1.1e-10 41.6 23.1 1.1 1 0 0 1 1 1 1 TLC domain DUF493 PF04359.14 GAX19235.1 - 5.1e-18 65.4 0.1 9.1e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF493) ACT_4 PF13291.6 GAX19235.1 - 0.15 12.7 0.0 0.25 12.0 0.0 1.3 1 0 0 1 1 1 0 ACT domain MatE PF01554.18 GAX19236.1 - 2.2e-13 50.2 19.9 1.9e-11 43.9 4.6 3.3 3 1 1 4 4 4 2 MatE Polysacc_synt_C PF14667.6 GAX19236.1 - 5.1e-07 29.8 6.8 5.1e-07 29.8 6.8 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain SET PF00856.28 GAX19237.1 - 1.4e-05 25.5 0.0 5.7e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 GAX19237.1 - 0.024 15.3 0.0 0.046 14.4 0.0 1.5 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding tRNA-synt_2b PF00587.25 GAX19238.1 - 9.5e-45 152.7 0.0 2e-44 151.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAX19238.1 - 1.4e-16 60.4 0.2 5.9e-16 58.4 0.2 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 GAX19238.1 - 8.6e-13 48.2 0.0 1.9e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Cyclin PF08613.11 GAX19239.1 - 3.7e-35 121.7 1.7 8.8e-35 120.5 1.6 1.6 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAX19239.1 - 1.1e-11 44.6 0.2 1.8e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PEX11 PF05648.14 GAX19240.1 - 5.6e-21 75.0 0.9 6.7e-13 48.6 0.1 3.1 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF3395 PF11875.8 GAX19241.1 - 7.1e-21 74.7 0.1 6.3e-20 71.6 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) Terminase_5 PF06056.12 GAX19241.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) MEIOC PF15189.6 GAX19241.1 - 0.18 11.4 1.2 0.33 10.6 1.2 1.3 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC Efg1 PF10153.9 GAX19242.1 - 8.8e-14 51.8 12.5 8.8e-14 51.8 12.5 3.0 3 1 0 3 3 3 1 rRNA-processing protein Efg1 DUF5499 PF17603.2 GAX19242.1 - 0.019 15.5 0.7 0.082 13.5 0.7 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5499) Pkinase PF00069.25 GAX19243.1 - 1.6e-23 83.5 0.0 2.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19243.1 - 4.8e-09 35.9 0.0 3.8e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX19243.1 - 0.00057 19.3 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like L-fibroin PF05849.11 GAX19243.1 - 0.11 11.8 0.2 4.2 6.6 0.0 2.2 1 1 1 2 2 2 0 Fibroin light chain (L-fibroin) FGGY_C PF02782.16 GAX19244.1 - 1.3e-60 204.5 4.7 1.1e-59 201.6 2.0 2.7 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAX19244.1 - 1.7e-57 194.8 0.1 2.7e-57 194.2 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DHR-2 PF06920.13 GAX19245.1 - 3.5e-17 62.3 0.0 3.1e-07 29.4 0.0 3.3 3 0 0 3 3 3 3 Dock homology region 2 DDHD PF02862.17 GAX19246.1 - 5.6e-21 75.7 0.0 7.4e-19 68.8 0.0 2.3 1 1 0 1 1 1 1 DDHD domain DUF676 PF05057.14 GAX19246.1 - 0.017 14.7 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) CIA30 PF08547.12 GAX19247.1 - 4.8e-14 52.7 0.0 7.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 GAX19247.1 - 0.056 13.4 0.7 0.11 12.5 0.7 1.8 1 1 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain UBA_e1_thiolCys PF10585.9 GAX19248.1 - 2.7e-05 24.3 0.9 2.8e-05 24.2 0.9 1.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site GUCT PF08152.12 GAX19248.1 - 0.066 13.5 0.0 0.14 12.4 0.0 1.6 1 1 1 2 2 2 0 GUCT (NUC152) domain DUF2009 PF09418.10 GAX19249.1 - 6.6e-190 632.0 0.0 8.9e-190 631.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) HATPase_c PF02518.26 GAX19249.1 - 0.00043 20.8 0.0 0.17 12.4 0.0 3.0 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX19249.1 - 0.00051 19.9 0.0 0.037 13.8 0.0 3.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4637 PF15470.6 GAX19249.1 - 0.17 11.6 3.2 0.49 10.1 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Kelch_1 PF01344.25 GAX19250.1 - 1.9e-40 136.2 13.2 1.2e-08 34.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAX19250.1 - 7e-34 115.5 17.6 1.7e-10 40.9 0.4 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAX19250.1 - 1.2e-28 98.6 17.9 2.4e-05 24.2 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAX19250.1 - 6.2e-27 92.9 16.6 2.3e-05 24.5 0.1 6.3 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAX19250.1 - 2.8e-26 90.5 14.6 6.5e-05 22.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAX19250.1 - 1.8e-24 85.4 16.9 3.5e-06 26.9 0.2 6.4 5 1 1 6 6 6 4 Galactose oxidase, central domain BTB PF00651.31 GAX19250.1 - 2.5e-24 85.6 1.0 2.5e-24 85.6 1.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 GAX19250.1 - 4e-05 23.6 1.5 0.00026 21.1 0.2 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Cu-oxidase_2 PF07731.14 GAX19250.1 - 0.04 13.6 0.3 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Multicopper oxidase DUF3342 PF11822.8 GAX19250.1 - 0.16 12.2 0.2 0.37 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) SET PF00856.28 GAX19251.1 - 3.3e-12 47.1 0.1 1.1e-07 32.5 0.0 2.2 1 1 1 2 2 2 2 SET domain Viral_DNA_Zn_bi PF03728.13 GAX19251.1 - 0.0071 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Viral DNA-binding protein, zinc binding domain NAD_binding_10 PF13460.6 GAX19253.1 - 4.6e-29 101.6 0.0 1.5e-28 100.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 GAX19253.1 - 0.0031 17.6 0.0 0.0078 16.3 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 GAX19253.1 - 0.0077 15.8 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.24 GAX19253.1 - 0.016 15.6 0.0 0.037 14.5 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 GAX19253.1 - 0.023 13.8 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAX19253.1 - 0.055 12.9 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX19253.1 - 0.074 12.0 0.0 7 5.6 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acetyltransf_1 PF00583.25 GAX19254.1 - 7.9e-12 45.4 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAX19254.1 - 1.8e-07 31.0 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 GAX19254.1 - 7e-07 29.6 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX19254.1 - 0.00031 20.7 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX19254.1 - 0.17 12.0 0.1 1.3 9.1 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF5465 PF17553.2 GAX19255.1 - 0.036 14.5 0.3 0.13 12.8 0.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5465) DNA_pol_E_B PF04042.16 GAX19255.1 - 0.11 11.9 0.6 1.7 8.0 0.0 2.6 2 1 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B Ras PF00071.22 GAX19256.1 - 1.5e-46 157.9 0.0 1.9e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX19256.1 - 5.9e-27 94.3 0.1 1.2e-26 93.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX19256.1 - 2.7e-14 53.0 0.0 3.6e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAX19256.1 - 3.3e-07 30.4 0.0 0.0044 16.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAX19256.1 - 7.6e-06 25.5 0.0 9.7e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX19256.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAX19256.1 - 8.4e-05 22.4 0.0 0.00019 21.2 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 GAX19256.1 - 0.00068 19.1 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 GAX19256.1 - 0.0033 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX19256.1 - 0.011 16.3 0.0 0.022 15.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 GAX19256.1 - 0.014 15.8 0.2 0.042 14.2 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 GAX19256.1 - 0.024 13.5 0.2 0.42 9.4 0.1 2.2 1 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_28 PF13521.6 GAX19256.1 - 0.032 14.5 0.0 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX19256.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX19256.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PhetRS_B1 PF18262.1 GAX19256.1 - 0.15 12.3 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain TFIIS_C PF01096.18 GAX19257.1 - 6.4e-15 54.7 1.0 6.4e-15 54.7 1.0 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-TFIIB PF13453.6 GAX19257.1 - 0.0034 16.7 3.1 0.31 10.4 1.0 2.4 2 0 0 2 2 2 2 Transcription factor zinc-finger RNA_POL_M_15KD PF02150.16 GAX19257.1 - 0.004 17.0 1.8 0.3 11.0 0.2 2.6 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 GAX19257.1 - 0.0088 16.0 7.9 0.1 12.6 0.3 2.9 2 1 0 2 2 2 1 Double zinc ribbon zinc_ribbon_4 PF13717.6 GAX19257.1 - 0.049 13.6 10.0 0.45 10.5 0.1 3.7 3 1 1 4 4 4 0 zinc-ribbon domain RPA_interact_C PF14768.6 GAX19257.1 - 0.12 13.0 2.1 0.19 12.3 2.1 1.4 1 1 0 1 1 1 0 Replication protein A interacting C-terminal C1_1 PF00130.22 GAX19257.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.13 GAX19257.1 - 0.41 10.4 8.8 0.38 10.5 0.5 3.0 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit LRV_FeS PF05484.11 GAX19257.1 - 0.46 10.5 3.4 17 5.5 0.1 2.9 3 0 0 3 3 3 0 LRV protein FeS4 cluster Zn_Tnp_IS1595 PF12760.7 GAX19257.1 - 0.66 10.0 7.0 3.5 7.7 0.9 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 GAX19257.1 - 0.7 10.1 6.8 22 5.2 0.0 3.8 4 0 0 4 4 4 0 Zinc ribbon domain PHD PF00628.29 GAX19257.1 - 0.79 9.7 7.9 0.25 11.3 0.6 2.5 2 1 0 2 2 2 0 PHD-finger Elf1 PF05129.13 GAX19257.1 - 0.88 9.7 6.5 7.5 6.7 0.1 3.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.12 GAX19257.1 - 0.89 9.6 6.4 2.2 8.3 0.2 2.6 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_5 PF13719.6 GAX19257.1 - 0.9 9.3 7.1 2.5 8.0 0.2 3.7 3 1 1 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 GAX19257.1 - 4.6 7.2 6.2 5.9 6.9 0.7 2.3 2 1 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.9 GAX19257.1 - 8.7 6.5 11.8 4.7 7.4 0.2 3.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 C1_4 PF07975.12 GAX19257.1 - 9.5 6.6 9.5 0.48 10.7 0.5 2.9 2 2 0 2 2 2 0 TFIIH C1-like domain Pkinase_Tyr PF07714.17 GAX19258.1 - 0.0035 16.7 0.0 0.055 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GAX19258.1 - 0.0069 15.8 0.1 0.027 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Mg_chelatase_C PF13335.6 GAX19258.1 - 0.075 13.7 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Ank_2 PF12796.7 GAX19259.1 - 6.7e-16 58.7 0.0 9.5e-13 48.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAX19259.1 - 2.8e-13 49.7 0.0 0.015 15.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 GAX19259.1 - 4.5e-12 46.2 0.0 1.1e-06 29.0 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX19259.1 - 5.8e-11 42.4 0.0 0.00067 19.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19259.1 - 5e-09 35.7 0.0 0.018 15.5 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat Pkinase PF00069.25 GAX19260.1 - 4.8e-08 32.7 0.2 2.9e-07 30.1 0.1 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19260.1 - 3.6e-05 23.2 0.1 8.9e-05 21.9 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Tweety PF04906.13 GAX19261.1 - 0.00013 20.8 1.9 0.0017 17.1 1.9 2.1 1 1 0 1 1 1 1 Tweety DUF5305 PF17231.2 GAX19261.1 - 2.6 7.4 4.8 1.7 8.0 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Yip1 PF04893.17 GAX19261.1 - 3.2 7.5 18.8 7.5 6.2 7.5 3.8 4 0 0 4 4 4 0 Yip1 domain DUF4131 PF13567.6 GAX19262.1 - 9.3 5.9 10.5 4.6 6.9 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Glu_cyclase_2 PF05096.12 GAX19263.1 - 4e-73 246.0 0.3 5.2e-73 245.6 0.3 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase ATP-synt_8 PF00895.20 GAX19263.1 - 0.054 14.0 0.8 0.11 13.0 0.8 1.5 1 0 0 1 1 1 0 ATP synthase protein 8 ADH_N PF08240.12 GAX19265.1 - 1.5e-31 108.5 0.2 1.5e-31 108.5 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAX19265.1 - 6.2e-27 94.1 1.4 7.6e-27 93.9 0.5 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAX19265.1 - 3.9e-05 24.7 0.0 7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAX19265.1 - 9.5e-05 22.0 0.2 0.00015 21.3 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 GAX19265.1 - 0.0031 16.8 0.6 0.0048 16.2 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 GAX19265.1 - 0.0033 17.0 0.5 0.0049 16.5 0.5 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 GAX19265.1 - 0.01 16.4 0.2 0.024 15.3 0.2 1.6 1 0 0 1 1 1 0 PglD N-terminal domain 2-Hacid_dh_C PF02826.19 GAX19265.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ysc84 PF04366.12 GAX19266.1 - 3.8e-32 110.7 1.4 1.6e-31 108.7 0.1 2.6 3 0 0 3 3 3 1 Las17-binding protein actin regulator PDZ_6 PF17820.1 GAX19266.1 - 0.15 11.9 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 PDZ domain NAP PF00956.18 GAX19267.1 - 6.8e-74 248.4 1.7 8.3e-74 248.1 1.7 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) FCH PF00611.23 GAX19267.1 - 0.033 14.5 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain ING PF12998.7 GAX19267.1 - 0.17 12.5 2.9 0.26 11.9 0.3 2.5 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Myb_DNA-binding PF00249.31 GAX19268.1 - 3.4e-25 88.0 3.9 3.1e-13 49.7 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX19268.1 - 1.3e-18 67.0 4.4 4.5e-12 46.0 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX19268.1 - 6.6e-09 35.5 0.7 4.5e-08 32.9 0.3 2.4 2 0 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 GAX19268.1 - 9.8e-05 22.6 4.5 0.051 13.9 0.0 2.7 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GAX19268.1 - 9.9e-05 22.7 12.0 0.00017 21.9 1.1 2.8 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAX19268.1 - 0.0033 17.6 0.5 0.15 12.3 0.3 2.3 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 FtsJ PF01728.19 GAX19269.1 - 5.4e-64 215.5 0.0 7.7e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase FBPase PF00316.20 GAX19270.1 - 3.5e-42 144.0 1.3 5.4e-29 101.0 0.1 2.3 1 1 0 2 2 2 2 Fructose-1-6-bisphosphatase, N-terminal domain WD40 PF00400.32 GAX19271.1 - 2e-10 41.1 13.1 0.0048 17.7 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX19271.1 - 4.5e-08 33.3 0.2 0.075 13.3 0.0 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome PF00227.26 GAX19272.1 - 0.0052 16.3 0.0 0.42 10.1 0.0 2.3 2 1 0 2 2 2 2 Proteasome subunit DUF2046 PF09755.9 GAX19273.1 - 1.8e-11 43.8 20.1 2.5e-11 43.4 20.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF2570 PF10828.8 GAX19273.1 - 3.9 7.3 11.0 0.59 10.0 4.7 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) Yae1_N PF09811.9 GAX19274.1 - 0.00074 19.2 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Phage_pRha PF09669.10 GAX19274.1 - 0.041 14.4 0.0 0.067 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) ABC_ATPase PF09818.9 GAX19276.1 - 1.4e-100 337.2 0.1 2.1e-81 274.0 0.2 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 GAX19276.1 - 0.27 11.7 0.0 0.27 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain TIC20 PF16166.5 GAX19278.1 - 2.4e-14 53.5 0.0 2.9e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like bZIP_1 PF00170.21 GAX19279.1 - 7.8e-06 25.9 9.9 2.3e-05 24.4 9.9 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX19279.1 - 0.0033 17.5 3.0 0.0033 17.5 3.0 3.8 3 1 1 4 4 4 2 Basic region leucine zipper GAF_2 PF13185.6 GAX19279.1 - 0.042 14.2 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 GAF domain SLC12 PF03522.15 GAX19279.1 - 8.1 5.3 9.3 12 4.8 9.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 NDUFB10 PF10249.9 GAX19280.1 - 5.7e-06 26.9 0.5 6.4e-06 26.7 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF676 PF05057.14 GAX19281.1 - 8.7e-27 94.1 0.0 2.9e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAX19281.1 - 0.00032 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 GAX19281.1 - 0.00038 20.4 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 GAX19281.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 3) Cys_Met_Meta_PP PF01053.20 GAX19282.1 - 3.5e-125 417.5 0.0 4e-125 417.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAX19282.1 - 2.2e-08 33.7 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAX19282.1 - 1.6e-06 27.7 0.1 2.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAX19282.1 - 1.8e-05 23.9 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MatE PF01554.18 GAX19284.1 - 1.6e-25 89.6 21.8 2.7e-21 75.9 7.3 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAX19284.1 - 2.8e-06 27.4 6.7 2.8e-06 27.4 6.7 3.9 4 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF2208 PF09973.9 GAX19284.1 - 0.56 9.8 2.2 8.6 5.9 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) EF-hand_1 PF00036.32 GAX19285.1 - 8.2e-10 37.5 1.9 2.6e-05 23.4 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX19285.1 - 1.8e-09 36.7 0.6 0.00032 20.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX19285.1 - 6.9e-08 31.6 6.5 0.0003 20.1 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 GAX19285.1 - 6.8e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX19285.1 - 2.5e-05 24.0 0.9 0.00044 20.0 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair G10 PF01125.17 GAX19287.1 - 4.8e-21 75.1 0.4 4.8e-21 75.1 0.4 1.6 2 0 0 2 2 2 1 G10 protein Trypan_PARP PF05887.11 GAX19287.1 - 0.35 10.9 9.2 0.51 10.3 9.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SURF2 PF05477.11 GAX19287.1 - 4.2 7.0 10.5 5.6 6.6 10.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Adeno_E3_CR2 PF02439.15 GAX19288.1 - 0.015 15.1 0.5 0.033 14.0 0.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pelovaterin PF17859.1 GAX19288.1 - 0.092 13.0 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Pelovaterin Methyltransf_11 PF08241.12 GAX19289.1 - 2.4e-15 57.0 0.0 8.7e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX19289.1 - 1.4e-13 51.3 0.0 1.1e-12 48.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX19289.1 - 3.1e-09 36.9 0.0 8.9e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX19289.1 - 4.9e-08 33.6 0.0 2e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX19289.1 - 2.9e-07 30.4 0.0 0.00036 20.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_8 PF05148.15 GAX19289.1 - 1.1e-05 25.4 0.0 0.0039 17.1 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase Ubie_methyltran PF01209.18 GAX19289.1 - 1.2e-05 24.8 0.0 4.2e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAX19289.1 - 0.00038 19.8 0.0 0.009 15.3 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 GAX19289.1 - 0.00058 19.4 0.0 0.051 13.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 GAX19289.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 GAX19289.1 - 0.11 12.0 0.0 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.6 GAX19289.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mem_trans PF03547.18 GAX19290.1 - 2.6e-12 45.8 6.2 1.5e-11 43.4 6.2 2.0 1 1 0 1 1 1 1 Membrane transport protein Sec8_exocyst PF04048.14 GAX19291.1 - 0.00028 20.8 5.1 0.0019 18.1 0.6 3.2 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain NUDIX PF00293.28 GAX19292.1 - 1.2e-08 35.1 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain AGOG PF09171.10 GAX19293.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 N-glycosylase/DNA lyase TBCC PF07986.12 GAX19294.1 - 7.8e-19 67.6 0.1 1.5e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF728 PF05304.12 GAX19294.1 - 0.05 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF728) PY_rept_46 PF09689.10 GAX19294.1 - 6.6 7.4 9.2 0.92 10.1 4.0 2.3 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Laminin_G_3 PF13385.6 GAX19295.1 - 0.027 14.6 0.0 0.09 12.9 0.0 2.0 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily LrgB PF04172.16 GAX19296.1 - 8.1e-42 143.2 15.6 8.1e-42 143.2 15.6 2.2 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 GAX19296.1 - 0.00052 19.9 1.9 0.00052 19.9 1.9 3.8 4 0 0 4 4 4 2 LrgA family OMPdecase PF00215.24 GAX19297.1 - 2.1e-30 106.0 0.0 2.5e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Macro PF01661.21 GAX19298.1 - 5.3e-26 91.0 0.0 7.8e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Macro domain Ank_4 PF13637.6 GAX19299.1 - 1.3e-11 44.8 0.3 5.6e-11 42.8 0.1 2.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX19299.1 - 1e-10 42.1 0.0 1.8e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX19299.1 - 1e-10 41.6 1.3 1.5e-08 34.7 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19299.1 - 3.4e-09 36.2 0.1 4.4e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAX19299.1 - 2.8e-05 24.3 0.0 0.00016 22.0 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeat DUF2672 PF10878.8 GAX19299.1 - 0.13 12.3 0.1 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) zinc_ribbon_16 PF17034.5 GAX19300.1 - 8.6e-24 84.1 13.3 3.3e-23 82.2 13.3 2.0 1 1 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 GAX19300.1 - 0.0029 17.2 8.6 0.0029 17.2 8.6 2.4 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type Pex26 PF07163.12 GAX19300.1 - 0.022 14.1 0.9 0.031 13.6 0.1 1.6 2 0 0 2 2 2 0 Pex26 protein Baculo_LEF-11 PF06385.12 GAX19300.1 - 0.12 12.9 0.1 0.31 11.6 0.1 1.6 1 0 0 1 1 1 0 Baculovirus LEF-11 protein His_Phos_1 PF00300.22 GAX19301.1 - 6.1e-27 94.6 0.0 2.6e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) CDK5_activator PF03261.15 GAX19302.1 - 5.1 6.5 20.1 9.8 5.6 20.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein G-patch_2 PF12656.7 GAX19303.1 - 8.2e-16 57.8 0.1 8.2e-16 57.8 0.1 2.2 2 0 0 2 2 2 1 G-patch domain KN17_SH3 PF18131.1 GAX19303.1 - 4.5e-06 26.7 0.3 1.4e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain PALP PF00291.25 GAX19304.1 - 7.9e-53 179.8 0.0 1.1e-52 179.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PDH PF02153.17 GAX19304.1 - 0.053 12.5 0.0 0.18 10.8 0.0 1.8 1 1 1 2 2 2 0 Prephenate dehydrogenase FdhD-NarQ PF02634.15 GAX19304.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 FdhD/NarQ family Homoserine_dh PF00742.19 GAX19305.1 - 1.6e-51 174.7 0.0 3e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GAX19305.1 - 4.9e-15 56.2 0.0 8.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 GAX19305.1 - 0.00057 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain GFO_IDH_MocA PF01408.22 GAX19305.1 - 0.073 13.9 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Utp12 PF04003.12 GAX19306.1 - 5.3e-08 33.1 0.5 2.1e-07 31.2 0.4 2.1 2 0 0 2 2 2 1 Dip2/Utp12 Family AAA_11 PF13086.6 GAX19306.1 - 0.0051 16.6 0.2 0.0087 15.9 0.2 1.3 1 0 0 1 1 1 1 AAA domain PQQ_3 PF13570.6 GAX19306.1 - 0.15 12.6 0.5 0.39 11.3 0.5 1.7 1 0 0 1 1 1 0 PQQ-like domain YedD PF13987.6 GAX19308.1 - 0.053 13.3 0.2 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 YedD-like protein Shisa PF13908.6 GAX19308.1 - 0.19 11.9 0.2 0.19 11.9 0.2 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Glyco_hydro_38N PF01074.22 GAX19309.1 - 4.5e-92 308.5 7.2 5.9e-92 308.1 7.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 GAX19309.1 - 2.3e-19 69.3 0.0 6.4e-19 67.9 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 GAX19309.1 - 2e-15 57.5 0.0 4.3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Peroxin-3 PF04882.12 GAX19310.1 - 3.8e-10 39.4 7.7 0.0091 15.0 0.0 4.1 2 2 1 3 3 3 3 Peroxin-3 Dev_Cell_Death PF10539.9 GAX19311.1 - 1.5e-29 102.4 0.0 2.7e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Development and cell death domain zf-CCCH PF00642.24 GAX19311.1 - 2.2e-16 59.3 25.9 1.5e-09 37.6 3.6 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) YTH PF04146.15 GAX19311.1 - 2.1e-14 53.8 0.3 8.5e-14 51.8 0.3 1.9 1 1 0 1 1 1 1 YT521-B-like domain zf_CCCH_4 PF18345.1 GAX19311.1 - 2.4e-11 43.3 40.8 4.2e-06 26.6 4.4 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 GAX19311.1 - 1.9e-08 35.0 13.1 0.017 15.8 0.4 3.6 2 1 1 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 GAX19311.1 - 2.2e-07 30.5 7.8 1.1e-06 28.3 3.4 4.4 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAX19311.1 - 0.00052 20.4 37.1 0.0011 19.4 4.5 4.4 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 GAX19311.1 - 1.3 9.3 21.0 0.73 10.1 3.2 3.5 3 1 1 4 4 4 0 Zinc-finger containing family TPR_12 PF13424.6 GAX19312.1 - 5.1e-21 74.7 19.6 7.7e-08 32.5 0.2 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX19312.1 - 1.4e-16 59.8 24.9 2.2e-07 30.5 0.1 6.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX19312.1 - 0.00083 19.1 8.5 0.023 14.5 0.2 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX19312.1 - 0.0032 17.1 0.9 0.35 10.6 0.1 3.4 2 1 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 GAX19312.1 - 0.017 15.2 0.3 0.017 15.2 0.3 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat VirC2 PF07181.11 GAX19312.1 - 0.074 12.5 0.4 0.074 12.5 0.4 1.7 2 0 0 2 2 2 0 VirC2 protein DUF5344 PF17279.2 GAX19312.1 - 0.54 10.9 0.0 0.54 10.9 0.0 4.0 4 2 2 6 6 6 0 Family of unknown function (DUF5344) TPR_6 PF13174.6 GAX19312.1 - 1.4 9.8 11.0 30 5.5 0.1 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 GAX19313.1 - 2e-41 142.1 0.5 1.2e-34 119.9 0.7 2.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX19313.1 - 2.6e-05 23.8 0.3 0.001 18.5 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Zip PF02535.22 GAX19314.1 - 0.0048 16.2 3.1 0.0086 15.3 0.4 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter MNHE PF01899.16 GAX19314.1 - 3.1 7.5 14.4 1.2 8.9 0.1 3.6 2 2 2 4 4 4 0 Na+/H+ ion antiporter subunit Nucleoside_tran PF01733.18 GAX19315.1 - 7.8e-32 110.9 7.4 9.7e-30 104.0 0.5 2.9 3 0 0 3 3 3 2 Nucleoside transporter DUF2407_C PF13373.6 GAX19316.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain UT PF03253.14 GAX19318.1 - 1.9e-65 220.9 26.6 2.1e-65 220.7 26.6 1.0 1 0 0 1 1 1 1 Urea transporter Transket_pyr PF02779.24 GAX19320.1 - 1.1e-64 217.4 0.0 1.9e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 GAX19320.1 - 1.2e-59 201.7 0.0 2.1e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 GAX19320.1 - 7.6e-52 175.0 0.0 1.3e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 GAX19320.1 - 4.9e-16 58.0 2.1 8.3e-16 57.3 0.5 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Peptidase_M24_C PF16188.5 GAX19320.1 - 0.1 12.7 0.1 3 8.0 0.1 2.6 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 DUF1451 PF07295.11 GAX19320.1 - 0.14 12.2 0.2 0.32 11.0 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF3119 PF11317.8 GAX19321.1 - 8.9e-34 116.5 0.0 1.2e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) cNMP_binding PF00027.29 GAX19322.1 - 3.9e-16 58.9 0.0 1.1e-15 57.5 0.0 1.7 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Thioredoxin PF00085.20 GAX19322.1 - 1.3e-11 44.4 0.1 2.2e-10 40.5 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin EF-hand_7 PF13499.6 GAX19322.1 - 2.5e-08 34.2 2.7 0.00061 20.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX19322.1 - 1.5e-07 30.5 9.2 0.0001 21.6 0.1 4.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 GAX19322.1 - 2.2e-07 30.3 2.2 0.039 13.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GAX19322.1 - 1.4e-05 24.3 6.2 0.00048 19.5 0.2 3.0 3 0 0 3 3 3 2 EF hand Thioredoxin_2 PF13098.6 GAX19322.1 - 0.02 15.4 0.2 0.31 11.5 0.2 2.5 1 1 0 1 1 1 0 Thioredoxin-like domain EF-hand_8 PF13833.6 GAX19322.1 - 1.9 8.4 5.0 16 5.5 0.1 3.4 4 1 1 5 5 5 0 EF-hand domain pair FA_hydroxylase PF04116.13 GAX19323.1 - 1.9e-21 76.8 21.3 1.9e-21 76.8 21.3 2.1 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily SNAPc19 PF15497.6 GAX19324.1 - 2.6 8.6 10.2 0.25 11.8 3.0 3.2 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Pkinase PF00069.25 GAX19326.1 - 7.4e-34 117.3 0.0 8.2e-24 84.4 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19326.1 - 4.4e-28 98.3 0.0 1.8e-27 96.3 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase GTP_EFTU_D3 PF03143.17 GAX19327.1 - 3.1e-16 59.7 0.0 4.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAX19327.1 - 3.8e-09 36.8 0.6 7e-09 36.0 0.6 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAX19327.1 - 6.7e-07 29.1 2.3 2e-06 27.6 1.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 UQ_con PF00179.26 GAX19329.1 - 1.5e-40 138.1 0.0 1.7e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 GAX19329.1 - 0.059 13.0 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.25 GAX19330.1 - 1.4e-36 126.2 0.0 2e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19330.1 - 1.5e-28 99.8 0.0 2.3e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Chloroa_b-bind PF00504.21 GAX19331.1 - 2.7e-05 24.8 0.0 4.6e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Chlorophyll A-B binding protein MMR_HSR1 PF01926.23 GAX19332.1 - 4.3e-18 65.5 0.0 6.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX19332.1 - 2.5e-06 27.5 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAX19332.1 - 3.8e-06 26.5 0.0 1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAX19332.1 - 0.00012 21.7 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 GAX19332.1 - 0.0016 18.6 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 GAX19332.1 - 0.0019 17.2 0.0 0.0051 15.8 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAX19332.1 - 0.0021 18.1 0.4 0.012 15.7 0.2 2.0 1 1 1 2 2 2 1 Dynamin family Septin PF00735.18 GAX19332.1 - 0.008 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_29 PF13555.6 GAX19332.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX19332.1 - 0.068 13.7 0.0 0.14 12.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 GAX19332.1 - 0.13 12.6 0.0 0.83 10.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Ras PF00071.22 GAX19332.1 - 0.14 11.8 0.0 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Ras family AAA_22 PF13401.6 GAX19332.1 - 0.15 12.3 0.0 2.5 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.31 GAX19333.1 - 9.2e-19 67.3 2.6 2.2e-18 66.1 1.0 2.5 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 GAX19333.1 - 4.2e-17 62.1 0.3 1.6e-07 31.4 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX19333.1 - 8.6e-12 45.1 1.2 1.5e-05 25.2 0.1 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain RAC_head PF16717.5 GAX19333.1 - 1.7e-07 32.1 4.5 1.7e-07 32.1 4.5 3.1 2 0 0 2 2 2 1 Ribosome-associated complex head domain Nop53 PF07767.11 GAX19333.1 - 0.0028 17.1 25.2 0.0028 17.1 25.2 2.7 2 1 1 3 3 3 1 Nop53 (60S ribosomal biogenesis) DUP PF00674.18 GAX19333.1 - 0.13 12.4 0.1 0.57 10.3 0.1 2.1 2 0 0 2 2 2 0 DUP family Glutaredoxin PF00462.24 GAX19334.1 - 2.8e-16 59.5 0.0 3.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 GAX19334.1 - 0.00067 19.9 0.0 0.00083 19.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAX19334.1 - 0.0011 19.4 0.0 0.0013 19.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Inositol_P PF00459.25 GAX19335.1 - 9.2e-54 182.8 0.3 1.1e-53 182.5 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 GAX19335.1 - 0.074 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain zf-RING_2 PF13639.6 GAX19336.1 - 4.7e-12 46.0 7.3 4.7e-12 46.0 7.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GAX19336.1 - 1.9e-09 37.1 1.7 4.9e-09 35.8 1.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX19336.1 - 1.5e-08 34.3 7.7 3.6e-08 33.1 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX19336.1 - 6.9e-07 29.0 6.2 1.9e-06 27.7 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX19336.1 - 3.5e-06 27.2 12.0 3.8e-05 23.9 12.0 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX19336.1 - 5.6e-05 23.0 5.5 5.6e-05 23.0 5.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX19336.1 - 0.00049 20.1 2.3 0.00049 20.1 2.3 2.4 2 1 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 GAX19336.1 - 0.00056 20.0 4.8 0.0029 17.8 4.8 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAX19336.1 - 0.0015 18.3 4.1 0.0046 16.8 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX19336.1 - 0.0037 17.3 5.3 0.013 15.5 5.3 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 GAX19336.1 - 0.019 15.2 4.7 0.056 13.8 4.7 1.8 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 GAX19336.1 - 0.05 13.2 3.4 0.13 11.9 3.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX19336.1 - 0.74 9.7 11.3 5.6 6.9 10.1 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 GAX19336.1 - 1.1 9.2 6.0 2.1 8.3 3.5 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 GAX19336.1 - 1.3 9.2 10.7 2.2 8.5 7.7 2.8 2 1 0 2 2 2 0 RING-variant domain tRNA-synt_1g PF09334.11 GAX19337.1 - 2.8e-111 372.0 0.4 4.1e-66 223.3 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAX19337.1 - 2.4e-29 102.1 1.3 7.7e-16 57.5 0.0 3.6 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 GAX19337.1 - 2.8e-18 66.3 0.0 3.4e-10 39.8 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 GAX19337.1 - 0.068 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Methyltransf_16 PF10294.9 GAX19339.1 - 1.1e-18 67.5 0.0 1.6e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 GAX19339.1 - 0.00037 21.1 0.1 0.0015 19.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 GAX19339.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 GAX19339.1 - 0.0029 17.4 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX19339.1 - 0.032 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 GAX19339.1 - 0.042 14.5 0.4 0.12 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX19339.1 - 0.11 13.2 0.6 0.25 12.1 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain adh_short_C2 PF13561.6 GAX19339.1 - 0.19 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 GAX19339.1 - 0.21 11.4 0.3 0.65 9.8 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.27 GAX19340.1 - 2e-37 127.0 0.1 2.4e-16 59.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Bestrophin PF01062.21 GAX19341.1 - 3.2e-36 125.3 0.5 4.6e-36 124.7 0.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PPV_E1_N PF00524.18 GAX19341.1 - 0.04 14.3 0.2 0.56 10.6 0.1 2.1 2 0 0 2 2 2 0 E1 Protein, N terminal domain Trypsin PF00089.26 GAX19342.1 - 2.1e-37 129.1 0.0 3.7e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin DsbD PF02683.15 GAX19343.1 - 7.7e-34 117.4 7.3 1.9e-33 116.2 7.2 1.6 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 GAX19343.1 - 3e-10 40.4 8.3 3e-10 40.4 8.3 1.7 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region F_bP_aldolase PF01116.20 GAX19344.1 - 7.6e-92 307.7 0.0 8.9e-92 307.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ABC_sub_bind PF04392.12 GAX19344.1 - 0.12 11.6 0.1 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter substrate binding protein Lipase_GDSL_2 PF13472.6 GAX19344.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Cation_ATPase_C PF00689.21 GAX19345.1 - 5.8e-40 136.9 4.4 1.5e-39 135.6 4.4 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAX19345.1 - 1.2e-35 122.6 0.8 1.2e-35 122.6 0.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 GAX19345.1 - 7.6e-11 41.5 0.0 2.5e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 GAX19345.1 - 5.9e-06 26.7 0.6 0.0081 16.5 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAX19345.1 - 0.00038 20.3 1.2 0.00059 19.7 0.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX19345.1 - 0.0021 18.1 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) RibD_C PF01872.17 GAX19346.1 - 2.7e-18 66.5 0.2 8.4e-18 64.9 0.2 1.7 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 GAX19346.1 - 0.00092 18.9 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Cation_ATPase_C PF00689.21 GAX19347.1 - 6.5e-39 133.5 6.2 1.7e-38 132.2 6.2 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAX19347.1 - 3.7e-35 121.1 0.8 3.7e-35 121.1 0.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 GAX19347.1 - 1.8e-10 40.4 0.0 6e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 GAX19347.1 - 3.5e-06 27.5 1.2 0.01 16.1 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAX19347.1 - 0.00032 20.5 1.2 0.00061 19.6 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX19347.1 - 0.0034 17.4 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Lactamase_B_2 PF12706.7 GAX19348.1 - 9.5e-20 71.0 0.0 3.4e-19 69.2 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX19348.1 - 3.3e-05 24.0 0.0 7.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RPN7 PF10602.9 GAX19349.1 - 4.1e-20 72.2 5.4 1e-19 70.9 5.4 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAX19349.1 - 4.4e-06 27.2 0.5 1.6e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 PCI domain adh_short PF00106.25 GAX19350.1 - 4.7e-29 101.2 0.4 1.4e-25 89.9 0.6 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX19350.1 - 1.2e-15 57.7 0.2 7.8e-15 55.1 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX19350.1 - 1.1e-05 25.4 0.1 2.1e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX19350.1 - 0.00015 21.3 0.1 0.00044 19.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX19350.1 - 0.0014 18.5 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 GAX19350.1 - 0.0036 17.4 0.1 0.011 15.8 0.0 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 GAX19350.1 - 0.055 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Edc3_linker PF16598.5 GAX19350.1 - 0.06 14.0 0.4 0.15 12.8 0.4 1.6 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 NUDIX PF00293.28 GAX19351.1 - 1.1e-09 38.4 0.1 1.3e-08 34.9 0.1 2.2 1 1 0 1 1 1 1 NUDIX domain AAA PF00004.29 GAX19352.1 - 2.1e-36 125.2 0.0 1.6e-35 122.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAX19352.1 - 4.4e-08 33.0 1.4 4.6e-06 26.5 0.1 3.8 4 0 0 4 4 4 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 GAX19352.1 - 3.7e-06 26.6 0.0 3.2e-05 23.6 0.0 2.5 1 1 1 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 GAX19352.1 - 9.9e-06 26.0 1.6 0.00047 20.6 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 GAX19352.1 - 2.2e-05 23.7 0.0 4.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAX19352.1 - 3.7e-05 24.0 2.1 0.00039 20.7 0.0 3.1 2 2 1 3 3 3 1 AAA domain RuvB_N PF05496.12 GAX19352.1 - 3.8e-05 23.5 0.0 8.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAX19352.1 - 0.00025 21.2 0.3 0.00087 19.4 0.0 2.1 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX19352.1 - 0.00026 21.0 1.5 0.0012 18.8 0.0 2.9 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 GAX19352.1 - 0.00044 19.7 0.0 0.062 12.7 0.0 2.6 1 1 0 2 2 2 1 Bacterial TniB protein ResIII PF04851.15 GAX19352.1 - 0.00049 20.1 0.2 0.0029 17.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 GAX19352.1 - 0.00055 19.7 0.0 0.0026 17.5 0.0 2.1 1 1 1 2 2 2 1 IstB-like ATP binding protein MCM PF00493.23 GAX19352.1 - 0.00092 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MIT PF04212.18 GAX19352.1 - 0.0013 18.8 1.6 0.003 17.6 0.3 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_19 PF13245.6 GAX19352.1 - 0.004 17.5 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 GAX19352.1 - 0.0042 16.5 0.1 0.12 11.6 0.0 2.6 2 1 1 3 3 3 1 KaiC AAA_7 PF12775.7 GAX19352.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 GAX19352.1 - 0.0077 16.2 0.1 0.086 12.8 0.0 2.5 1 1 2 3 3 3 1 NACHT domain AAA_24 PF13479.6 GAX19352.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAX19352.1 - 0.011 15.1 0.7 0.22 10.8 0.0 2.9 3 1 0 3 3 3 0 Zeta toxin AAA_11 PF13086.6 GAX19352.1 - 0.011 15.6 0.0 0.011 15.6 0.0 2.9 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 GAX19352.1 - 0.014 14.8 0.0 0.014 14.8 0.0 2.1 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAX19352.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAX19352.1 - 0.014 14.6 0.0 0.067 12.4 0.0 1.9 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_33 PF13671.6 GAX19352.1 - 0.017 15.3 0.0 0.066 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX19352.1 - 0.021 14.5 0.0 0.075 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX19352.1 - 0.022 15.3 0.6 0.069 13.7 0.0 2.2 3 0 0 3 3 1 0 AAA domain TsaE PF02367.17 GAX19352.1 - 0.027 14.5 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAX19352.1 - 0.028 14.7 1.1 0.16 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX19352.1 - 0.049 13.2 0.1 0.37 10.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX19352.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase DUF572 PF04502.13 GAX19352.1 - 8.5 5.9 11.4 13 5.3 11.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CENP-O PF09496.10 GAX19353.1 - 1.4e-13 51.4 0.4 1.4e-13 51.4 0.4 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component AAA PF00004.29 GAX19354.1 - 2.5e-43 147.6 0.0 1.9e-41 141.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX19354.1 - 7.2e-05 22.6 0.0 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX19354.1 - 0.00068 20.1 0.3 0.011 16.1 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 GAX19354.1 - 0.0023 17.9 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 GAX19354.1 - 0.0049 16.6 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAX19354.1 - 0.0061 17.1 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAX19354.1 - 0.0061 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAX19354.1 - 0.0087 16.1 0.0 0.059 13.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAX19354.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX19354.1 - 0.015 15.6 0.2 0.81 10.0 0.1 2.7 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAX19354.1 - 0.024 14.5 0.0 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 GAX19354.1 - 0.047 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAX19354.1 - 0.049 12.8 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 GAX19354.1 - 0.078 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM_lid PF17855.1 GAX19354.1 - 0.092 13.2 0.0 0.49 10.9 0.0 2.2 2 0 0 2 2 2 0 MCM AAA-lid domain AAA_2 PF07724.14 GAX19354.1 - 0.14 12.3 0.0 0.62 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 GAX19354.1 - 0.2 11.6 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sulfotransfer_4 PF17784.1 GAX19355.1 - 8.2e-39 133.7 0.0 9.8e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX19355.1 - 0.0075 16.7 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family SET PF00856.28 GAX19357.1 - 1e-05 26.0 0.3 0.0042 17.5 0.1 3.3 2 1 0 2 2 2 2 SET domain Pkinase PF00069.25 GAX19358.1 - 1.4e-58 198.4 0.0 1.6e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19358.1 - 8.1e-46 156.4 0.0 9.7e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX19358.1 - 3.3e-05 23.3 0.0 0.00013 21.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAX19358.1 - 3.5e-05 23.3 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX19358.1 - 0.00072 18.4 0.0 0.00096 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAX19358.1 - 0.0028 16.7 0.1 0.0071 15.3 0.0 1.6 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAX19358.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 GAX19358.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RIO1 PF01163.22 GAX19358.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Sigma70_r2 PF04542.14 GAX19359.1 - 2.4e-16 59.3 0.0 6.3e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 GAX19359.1 - 4e-14 52.5 0.0 3.5e-13 49.4 0.1 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 GAX19359.1 - 8.7e-08 31.6 0.6 4.9e-07 29.2 0.3 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 GAX19359.1 - 0.027 14.1 1.5 5.1 6.9 0.0 3.1 2 1 0 2 2 2 0 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 GAX19359.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 RPAP1_N PF08621.10 GAX19360.1 - 0.62 9.9 12.5 3.7 7.4 2.2 2.7 2 0 0 2 2 2 0 RPAP1-like, N-terminal DUF4460 PF14687.6 GAX19361.1 - 1.9e-05 24.7 0.5 4e-05 23.6 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) Ribosomal_L27A PF00828.19 GAX19362.1 - 8.9e-23 81.4 0.2 8.9e-23 81.4 0.2 1.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 GAX19362.1 - 0.094 12.8 0.6 0.16 12.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) PCIF1_WW PF12237.8 GAX19363.1 - 1.7e-38 132.0 0.0 3.4e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain KNOX2 PF03791.13 GAX19363.1 - 0.12 11.9 0.2 14 5.3 0.0 2.7 2 0 0 2 2 2 0 KNOX2 domain PseudoU_synth_2 PF00849.22 GAX19364.1 - 2.6e-14 53.6 0.1 5.7e-14 52.5 0.1 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase adh_short PF00106.25 GAX19365.1 - 1.2e-22 80.4 0.0 2.7e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX19365.1 - 1.3e-11 44.5 0.0 2.5e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX19365.1 - 3.2e-06 27.2 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX19365.1 - 0.064 12.7 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Adenine_deam_C PF13382.6 GAX19365.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain Pribosyltran_N PF13793.6 GAX19366.1 - 4.3e-50 168.5 0.1 1.7e-49 166.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAX19366.1 - 5.6e-26 91.7 0.1 2.5e-25 89.6 0.1 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAX19366.1 - 9.2e-13 48.0 0.2 2e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAX19366.1 - 0.056 12.9 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase BSD PF03909.17 GAX19367.1 - 0.0016 18.4 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 BSD domain Metallophos PF00149.28 GAX19368.1 - 9.8e-12 45.8 0.2 1.3e-11 45.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX19368.1 - 0.016 15.4 0.0 6.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Ion_trans_2 PF07885.16 GAX19369.1 - 9.8e-31 105.6 12.8 7.1e-18 64.4 7.3 2.3 2 0 0 2 2 2 2 Ion channel EF-hand_5 PF13202.6 GAX19369.1 - 5.6e-10 38.3 2.0 3.5e-06 26.3 0.0 3.4 2 1 1 3 3 3 2 EF hand EF-hand_1 PF00036.32 GAX19369.1 - 4.4e-09 35.2 2.1 0.00016 21.0 0.1 3.2 2 1 1 3 3 3 2 EF hand EF-hand_7 PF13499.6 GAX19369.1 - 1.3e-08 35.2 0.1 0.0016 18.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX19369.1 - 4.3e-07 29.4 1.2 0.012 15.5 0.0 2.8 1 1 2 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GAX19369.1 - 0.0028 17.4 0.4 0.028 14.3 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain pair Ion_trans PF00520.31 GAX19369.1 - 0.0043 16.3 2.0 0.088 12.0 0.7 2.3 2 1 0 2 2 2 1 Ion transport protein Dockerin_1 PF00404.18 GAX19369.1 - 0.18 12.0 0.0 0.67 10.2 0.0 1.9 2 0 0 2 2 2 0 Dockerin type I domain ATP-synt_DE PF00401.20 GAX19369.1 - 1.9 8.8 6.7 1.7 9.0 5.2 1.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain FAD_binding_3 PF01494.19 GAX19370.1 - 2.5e-19 69.7 0.0 2.5e-10 40.2 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX19370.1 - 4.8e-08 33.0 0.1 2e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX19370.1 - 1.6e-05 24.1 0.1 2.4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 GAX19370.1 - 6.1e-05 22.2 0.0 0.0025 16.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 GAX19370.1 - 0.00016 21.8 0.3 0.0021 18.2 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAX19370.1 - 0.00036 19.1 0.0 0.00049 18.6 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAX19370.1 - 0.001 18.4 0.0 0.0021 17.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX19370.1 - 0.0017 17.7 0.0 0.0072 15.6 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAX19370.1 - 0.0079 15.6 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX19370.1 - 0.016 13.9 0.3 0.029 13.1 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 GAX19370.1 - 0.038 13.1 0.1 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAX19370.1 - 0.051 12.4 0.2 5.7 5.7 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.18 GAX19370.1 - 0.069 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAX19371.1 - 1.3e-11 44.4 0.0 1.1e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX19371.1 - 0.011 15.6 0.0 0.04 13.8 0.0 2.0 2 1 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAX19371.1 - 0.045 12.8 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Kelch_1 PF01344.25 GAX19372.1 - 1.9e-25 88.2 4.1 8.8e-08 31.6 0.3 6.7 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAX19372.1 - 1.3e-19 69.9 10.8 5.7e-06 26.2 0.1 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX19372.1 - 9.7e-18 63.8 11.3 2.5e-05 24.4 0.1 6.7 4 2 2 6 6 6 4 Kelch motif Kelch_5 PF13854.6 GAX19372.1 - 5.7e-14 51.7 6.2 9.3e-05 22.3 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 GAX19372.1 - 1.6e-13 50.5 14.7 0.001 19.3 0.3 5.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAX19372.1 - 3.5e-07 29.9 3.3 0.097 12.7 0.1 6.1 6 1 0 6 6 6 3 Kelch motif DUF4995 PF16386.5 GAX19373.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DEAD PF00270.29 GAX19374.1 - 8.2e-38 129.9 0.9 2.7e-37 128.2 0.2 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX19374.1 - 1.4e-19 70.5 0.0 4.7e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX19374.1 - 4.8e-05 23.4 0.6 0.00013 22.0 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAX19374.1 - 0.076 11.8 0.3 1.7 7.3 0.2 2.5 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 2OG-FeII_Oxy_2 PF13532.6 GAX19375.1 - 1.6e-16 61.1 0.0 1e-15 58.4 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 GAX19375.1 - 4.1e-11 43.4 0.0 1.1e-10 42.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX19375.1 - 1.1e-09 38.8 0.0 6.8e-09 36.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX19375.1 - 0.00022 21.9 0.0 0.00051 20.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX19375.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Prim-Pol PF09250.11 GAX19375.1 - 0.012 15.9 0.0 0.06 13.7 0.0 2.0 2 1 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal Aminotran_5 PF00266.19 GAX19376.1 - 1.5e-37 129.5 0.0 1e-28 100.4 0.0 2.6 2 1 1 3 3 3 2 Aminotransferase class-V TTL PF03133.15 GAX19376.1 - 4e-20 72.1 0.0 7.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAX19376.1 - 0.0017 17.6 0.0 0.0064 15.8 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp Aa_trans PF01490.18 GAX19377.1 - 4.9e-50 170.4 9.6 5.8e-50 170.2 9.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAX19377.1 - 1.1e-10 41.1 1.8 1.1e-10 41.1 1.8 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family HMG_box PF00505.19 GAX19378.1 - 2.3e-40 136.8 21.7 2.2e-21 76.0 3.0 2.6 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX19378.1 - 2.4e-26 92.1 17.2 7.3e-16 58.5 2.9 2.7 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.12 GAX19378.1 - 4.2e-06 26.6 0.0 0.068 13.1 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain HMG_box_5 PF14887.6 GAX19378.1 - 2.7e-05 24.0 10.5 0.0016 18.3 0.5 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box 5 YABBY PF04690.13 GAX19378.1 - 7.4e-05 23.4 11.7 0.059 13.9 0.7 2.3 1 1 1 2 2 2 2 YABBY protein RR_TM4-6 PF06459.12 GAX19378.1 - 0.0017 18.2 12.8 0.039 13.8 8.9 2.1 1 1 0 2 2 2 2 Ryanodine Receptor TM 4-6 NACHT PF05729.12 GAX19378.1 - 0.028 14.4 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain HTH_WhiA PF02650.14 GAX19378.1 - 0.03 14.7 0.1 15 6.0 0.0 2.8 2 1 1 3 3 3 0 WhiA C-terminal HTH domain Ccdc124 PF06244.12 GAX19378.1 - 0.73 10.4 15.1 1.7 9.2 0.8 3.5 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 Peptidase_C97 PF05903.14 GAX19379.1 - 2.3e-29 102.2 0.0 3.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain HD_4 PF13328.6 GAX19381.1 - 0.05 13.3 0.1 0.079 12.7 0.1 1.3 1 0 0 1 1 1 0 HD domain BRCA-2_OB3 PF09104.10 GAX19381.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF1995 PF09353.10 GAX19383.1 - 1.6e-39 136.0 0.0 1.9e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Acyl-CoA_dh_1 PF00441.24 GAX19384.1 - 6.3e-45 153.0 4.3 1.1e-44 152.2 4.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX19384.1 - 3.6e-36 124.3 0.1 2.2e-35 121.7 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAX19384.1 - 7.1e-27 93.5 0.1 1.4e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAX19384.1 - 3.1e-19 69.6 4.1 4.5e-19 69.1 4.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAX19384.1 - 0.012 15.3 0.2 0.032 13.9 0.0 1.8 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.6 GAX19384.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal DUF3228 PF11539.8 GAX19385.1 - 7.3e-80 267.1 0.0 8.5e-80 266.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) IFP_35_N PF07334.13 GAX19386.1 - 0.2 11.8 2.9 0.8 9.8 2.9 2.1 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TFA2_Winged_2 PF18121.1 GAX19387.1 - 3.1e-08 33.2 0.1 1.9e-07 30.7 0.0 2.4 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 GAX19387.1 - 0.0026 18.0 0.0 0.016 15.4 0.0 2.4 2 0 0 2 2 2 1 TFIIE beta subunit core domain FmiP_Thoc5 PF09766.9 GAX19388.1 - 3.4e-23 82.5 7.6 6.9e-19 68.4 3.2 3.3 3 1 0 3 3 3 2 Fms-interacting protein/Thoc5 COesterase PF00135.28 GAX19390.1 - 5.2e-104 348.9 0.1 1.5e-96 324.3 0.0 3.5 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAX19390.1 - 7.3e-08 32.5 0.1 8.9e-07 29.0 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX19390.1 - 0.014 14.9 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_U32 PF01136.19 GAX19390.1 - 0.07 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase family U32 RRM_1 PF00076.22 GAX19391.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF438 PF04282.13 GAX19391.1 - 0.22 11.5 1.0 0.4 10.7 0.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF438) HMA PF00403.26 GAX19392.1 - 0.0024 18.3 0.3 0.016 15.6 0.3 2.1 1 1 0 1 1 1 1 Heavy-metal-associated domain MerT PF02411.15 GAX19392.1 - 0.006 16.6 1.1 0.012 15.7 1.1 1.5 1 0 0 1 1 1 1 MerT mercuric transport protein DUF294 PF03445.13 GAX19392.1 - 0.099 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 CD52 PF15116.6 GAX19392.1 - 0.12 12.5 1.4 3.2 7.9 0.0 2.8 2 0 0 2 2 2 0 CAMPATH-1 antigen CLP_protease PF00574.23 GAX19393.1 - 9.7e-80 266.7 0.1 1.3e-79 266.4 0.1 1.1 1 0 0 1 1 1 1 Clp protease Lipase_3 PF01764.25 GAX19394.1 - 3.3e-12 46.5 0.0 6.1e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PRK PF00485.18 GAX19395.1 - 7.3e-36 123.8 0.0 9.2e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAX19395.1 - 8.6e-06 26.3 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX19395.1 - 0.00011 22.4 0.0 0.00023 21.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAX19395.1 - 0.00019 21.8 2.9 0.0045 17.4 2.9 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX19395.1 - 0.00031 20.1 0.0 0.00071 18.9 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 GAX19395.1 - 0.00095 19.4 0.0 0.72 10.1 0.0 2.4 1 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase dNK PF01712.19 GAX19395.1 - 0.0012 18.7 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_22 PF13401.6 GAX19395.1 - 0.0016 18.7 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 GAX19395.1 - 0.0018 18.0 1.6 0.23 11.1 0.0 2.3 2 1 0 2 2 2 1 Dephospho-CoA kinase ABC_tran PF00005.27 GAX19395.1 - 0.0019 18.7 0.0 0.0028 18.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 GAX19395.1 - 0.0039 17.1 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytidylate_kin PF02224.18 GAX19395.1 - 0.0058 16.4 0.3 0.81 9.4 0.0 2.2 1 1 0 2 2 2 1 Cytidylate kinase T2SSE PF00437.20 GAX19395.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 GAX19395.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 GAX19395.1 - 0.0073 16.2 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 GAX19395.1 - 0.0084 16.4 0.0 0.019 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAX19395.1 - 0.0085 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 GAX19395.1 - 0.012 15.5 0.1 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 GAX19395.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.27 GAX19395.1 - 0.024 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain APS_kinase PF01583.20 GAX19395.1 - 0.041 13.8 0.0 0.091 12.7 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.9 GAX19395.1 - 0.046 12.9 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 GAX19395.1 - 0.074 13.1 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 GAX19395.1 - 0.079 13.0 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ADK PF00406.22 GAX19395.1 - 0.093 12.8 0.5 6.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase KAP_NTPase PF07693.14 GAX19395.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain TsaE PF02367.17 GAX19395.1 - 0.11 12.5 0.4 0.19 11.7 0.4 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAX19395.1 - 0.12 12.7 0.1 0.35 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 GAX19395.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.5 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX19395.1 - 0.15 11.5 0.0 0.4 10.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ATG11 PF10377.9 GAX19396.1 - 1.6e-18 67.0 0.0 1.1e-17 64.3 0.0 2.3 2 1 1 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.12 GAX19396.1 - 9.8e-07 28.2 19.9 1.2e-05 24.6 15.9 3.1 2 1 0 2 2 2 1 Autophagy protein Apg17 LXG PF04740.12 GAX19396.1 - 0.00053 19.8 9.6 0.001 18.8 8.7 2.0 1 1 0 1 1 1 1 LXG domain of WXG superfamily AbiH PF14253.6 GAX19396.1 - 0.023 14.6 1.7 0.039 13.8 1.7 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH GCP_C_terminal PF04130.13 GAX19396.1 - 0.032 13.7 2.3 0.061 12.8 2.3 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal Prominin PF05478.11 GAX19396.1 - 0.035 12.1 5.1 0.067 11.2 5.1 1.4 1 0 0 1 1 1 0 Prominin DUF812 PF05667.11 GAX19396.1 - 0.067 12.1 13.7 0.054 12.4 8.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 GAX19396.1 - 0.078 13.2 13.7 0.077 13.2 6.9 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V-ATPase_G PF03179.15 GAX19396.1 - 0.11 13.1 5.6 0.32 11.6 5.6 1.9 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF773 PF05600.12 GAX19396.1 - 0.18 10.5 8.8 0.22 10.2 8.1 1.5 1 1 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF2458 PF10454.9 GAX19396.1 - 0.19 11.4 8.7 0.97 9.1 4.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) Syntaxin_2 PF14523.6 GAX19396.1 - 0.21 12.0 14.5 0.42 11.0 0.8 3.0 2 1 1 3 3 3 0 Syntaxin-like protein LMBR1 PF04791.16 GAX19396.1 - 0.21 10.4 7.4 0.39 9.6 7.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ku_PK_bind PF08785.11 GAX19396.1 - 0.31 11.2 4.5 1.1 9.5 3.0 2.6 1 1 0 1 1 1 0 Ku C terminal domain like AAA_13 PF13166.6 GAX19396.1 - 0.41 9.2 8.9 0.016 13.9 3.3 1.5 2 0 0 2 2 2 0 AAA domain ING PF12998.7 GAX19396.1 - 2.6 8.7 7.2 2.8 8.6 2.4 3.1 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding ApoLp-III PF07464.11 GAX19396.1 - 4.2 7.4 10.9 0.17 11.9 4.4 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Seryl_tRNA_N PF02403.22 GAX19396.1 - 6.5 7.0 12.8 0.78 10.0 2.3 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 GAX19396.1 - 8.2 6.5 10.5 3.9 7.5 0.7 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 GAX19396.1 - 8.6 6.7 10.4 62 3.9 4.7 3.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Peptidase_C54 PF03416.19 GAX19397.1 - 1.2e-72 244.6 0.0 1.7e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 GAX19397.1 - 0.027 14.0 0.1 0.051 13.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C78 Ank_5 PF13857.6 GAX19398.1 - 1.3e-18 66.8 0.0 4.2e-08 33.3 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX19398.1 - 1.7e-16 60.6 0.0 9.8e-08 32.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX19398.1 - 1.6e-13 49.5 0.3 0.17 12.5 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 GAX19398.1 - 7.4e-12 45.6 0.4 0.17 12.5 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAX19398.1 - 2.1e-10 40.5 2.5 1.1 9.9 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ion_trans PF00520.31 GAX19398.1 - 6.8e-08 32.0 18.4 1.2e-07 31.2 18.4 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GAX19398.1 - 0.0064 15.2 1.4 0.0064 15.2 1.4 2.9 2 1 1 3 3 3 1 Polycystin cation channel DUF1350 PF07082.11 GAX19400.1 - 2.2e-24 86.2 0.0 3.4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1350) XendoU PF09412.10 GAX19401.1 - 4.6e-90 301.4 0.2 7.6e-90 300.7 0.2 1.3 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 GAX19401.1 - 0.066 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial EndoU nuclease MCM PF00493.23 GAX19402.1 - 8.9e-70 234.3 0.0 5.2e-65 218.7 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 GAX19402.1 - 2.5e-22 79.1 2.5 4.3e-22 78.3 0.5 2.3 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 GAX19402.1 - 7.4e-19 68.0 0.4 7.4e-19 68.0 0.4 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAX19402.1 - 4.2e-08 32.8 0.1 3.9e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX19402.1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX19402.1 - 0.0072 16.7 0.4 0.087 13.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain MCM_N PF14551.6 GAX19402.1 - 0.019 15.6 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain AAA_22 PF13401.6 GAX19402.1 - 0.04 14.2 0.2 0.13 12.5 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 GAX19402.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 GAX19402.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 GAX19402.1 - 0.089 12.5 0.0 0.85 9.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 GAX19402.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 GAX19402.1 - 0.15 11.8 0.1 0.4 10.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain ANAPC1 PF12859.7 GAX19404.1 - 1.8e-07 31.8 0.3 0.013 16.1 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 GAX19404.1 - 0.084 13.3 0.1 0.084 13.3 0.1 5.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat zf-RING_11 PF17123.5 GAX19406.1 - 2e-06 27.4 6.3 0.00092 18.9 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 GAX19406.1 - 2e-05 24.3 5.5 2.4e-05 24.1 1.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX19406.1 - 2.8e-05 24.0 0.1 0.00012 21.9 0.1 2.2 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX19406.1 - 4.9e-05 23.3 1.4 0.00017 21.6 0.2 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX19406.1 - 9.7e-05 22.6 15.9 0.0033 17.7 8.2 3.6 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 GAX19406.1 - 0.00011 22.4 14.0 0.0019 18.5 14.0 2.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX19406.1 - 0.00024 20.9 4.4 0.005 16.7 0.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 GAX19406.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 GAX19406.1 - 0.0031 17.5 5.2 0.62 10.2 5.8 3.0 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_C25_C PF03785.14 GAX19406.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain Zn_ribbon_17 PF17120.5 GAX19406.1 - 0.085 12.5 0.2 0.085 12.5 0.2 2.1 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type bMG5 PF17972.1 GAX19406.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain zf-C3H2C3 PF17122.5 GAX19406.1 - 0.16 12.0 1.7 2 8.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger Prok-RING_4 PF14447.6 GAX19406.1 - 0.22 11.4 3.4 1.1 9.2 0.1 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 GAX19406.1 - 0.24 11.6 8.4 6.8 6.9 8.4 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 GAX19406.1 - 0.4 10.6 0.1 0.4 10.6 0.1 2.8 3 0 0 3 3 3 0 PHD-finger zf-C3HC4_3 PF13920.6 GAX19406.1 - 0.89 9.5 5.8 1.4 8.8 0.4 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAX19406.1 - 1 9.6 9.5 16 5.8 0.6 3.7 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING Tmpp129 PF10272.9 GAX19406.1 - 1.7 7.9 10.1 1.4 8.1 5.3 2.7 3 0 0 3 3 3 0 Putative transmembrane protein precursor Adipogenin PF15202.6 GAX19406.1 - 3.3 7.8 5.3 33 4.6 1.1 2.7 3 0 0 3 3 3 0 Adipogenin RINGv PF12906.7 GAX19406.1 - 7.2 6.8 9.4 1.2e+02 3.0 9.4 2.9 1 1 0 1 1 1 0 RING-variant domain peroxidase PF00141.23 GAX19407.1 - 2.9e-44 151.5 0.0 3.7e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Redoxin PF08534.10 GAX19408.1 - 8.2e-15 54.8 0.0 2e-14 53.6 0.0 1.6 1 1 1 2 2 2 1 Redoxin Utp11 PF03998.13 GAX19409.1 - 4.6e-64 216.7 30.5 5.8e-64 216.4 30.5 1.1 1 0 0 1 1 1 1 Utp11 protein DUF357 PF04010.13 GAX19409.1 - 0.17 12.0 2.3 0.18 11.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF357) Nic96 PF04097.14 GAX19410.1 - 1e-31 110.1 0.0 2.4e-31 108.9 0.0 1.6 1 1 0 1 1 1 1 Nup93/Nic96 Pro_isomerase PF00160.21 GAX19411.1 - 1.5e-38 132.6 1.0 4.9e-38 130.9 0.0 2.2 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 GAX19411.1 - 8.8e-13 49.0 22.0 8.4e-12 45.8 22.0 2.2 1 1 0 1 1 1 1 SYF2 splicing factor Acyl-CoA_dh_1 PF00441.24 GAX19411.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DNA_pol_phi PF04931.13 GAX19411.1 - 2.7 6.0 16.4 3.9 5.4 16.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi TPR_2 PF07719.17 GAX19413.1 - 1.2e-09 37.5 0.0 0.33 11.2 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX19413.1 - 4.2e-06 26.9 3.2 0.091 13.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX19413.1 - 6.2e-06 26.3 0.3 0.094 12.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX19413.1 - 0.00071 19.3 0.1 0.047 13.5 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX19413.1 - 0.00072 19.6 0.0 0.1 12.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX19413.1 - 0.071 13.2 0.5 57 4.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX19413.1 - 0.093 13.4 0.0 58 4.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 GAX19413.1 - 0.096 12.8 0.0 0.39 10.8 0.0 2.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain C1_2 PF03107.16 GAX19414.1 - 0.00025 21.3 6.6 0.00045 20.5 6.6 1.4 1 0 0 1 1 1 1 C1 domain ZZ PF00569.17 GAX19414.1 - 0.81 9.6 9.9 0.1 12.5 5.3 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-B_box PF00643.24 GAX19414.1 - 2 8.6 5.2 4.8 7.4 5.2 1.6 1 0 0 1 1 1 0 B-box zinc finger Tnp_zf-ribbon_2 PF13842.6 GAX19414.1 - 3.1 8.7 5.2 6.2 7.7 5.2 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Abhydrolase_6 PF12697.7 GAX19415.1 - 3.2e-18 67.2 0.0 4.3e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX19415.1 - 8.3e-16 58.0 0.0 3.7e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX19415.1 - 2e-12 47.3 0.1 5.6e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX19415.1 - 6.4e-05 22.5 0.0 0.00022 20.8 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 GAX19415.1 - 0.0013 18.6 0.0 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase DTC PF18102.1 GAX19415.1 - 0.0024 18.0 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Deltex C-terminal domain Abhydrolase_5 PF12695.7 GAX19415.1 - 0.1 12.3 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Spermine_synth PF01564.17 GAX19416.1 - 2.2e-62 209.9 0.0 3.1e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GAX19416.1 - 1.3e-23 82.6 0.1 2.3e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAX19416.1 - 1.3e-05 25.8 0.0 5.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX19416.1 - 9.5e-05 22.2 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX19416.1 - 0.03 15.1 0.0 0.078 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF1517 PF07466.11 GAX19417.1 - 7.7e-42 143.5 0.2 1e-41 143.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) TF_Zn_Ribbon PF08271.12 GAX19418.1 - 2.1e-11 43.1 0.5 4.3e-11 42.1 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 GAX19418.1 - 0.076 12.7 1.1 0.17 11.6 1.1 1.7 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF2935 PF11155.8 GAX19418.1 - 0.26 11.6 2.9 1.1 9.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) CCDC92 PF14916.6 GAX19418.1 - 9.9 6.0 10.8 0.14 12.0 3.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DEAD PF00270.29 GAX19419.1 - 4.8e-32 111.1 0.9 1.6e-31 109.4 0.4 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX19419.1 - 4.7e-26 91.3 0.4 2.8e-22 79.1 0.1 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAX19419.1 - 5.1e-07 29.9 0.0 1.9e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 GAX19419.1 - 0.00037 19.3 0.0 0.00068 18.5 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.14 GAX19419.1 - 0.0011 18.4 0.0 0.3 10.3 0.0 2.3 2 0 0 2 2 2 2 SecA DEAD-like domain SWI2_SNF2 PF18766.1 GAX19419.1 - 0.0027 17.4 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 GAX19419.1 - 0.039 13.7 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 GAX19419.1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Helicase_C_2 PF13307.6 GAX19419.1 - 0.088 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Ion_trans PF00520.31 GAX19420.1 - 4.3e-37 127.7 31.4 8.7e-19 67.7 9.1 2.5 2 1 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 GAX19420.1 - 1.4e-07 30.6 8.5 1.4e-07 30.6 8.5 3.3 2 1 1 3 3 3 2 Polycystin cation channel EF-hand_7 PF13499.6 GAX19420.1 - 0.0047 17.4 0.0 0.0086 16.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair DUF2663 PF10864.8 GAX19420.1 - 0.014 15.8 2.4 0.069 13.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) RVT_2 PF07727.14 GAX19421.1 - 3.5e-19 69.4 0.0 1.9e-18 67.0 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HATPase_c PF02518.26 GAX19422.1 - 3.9e-17 62.8 0.0 9.7e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 GAX19422.1 - 0.012 16.2 0.1 0.034 14.8 0.1 1.7 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.6 GAX19422.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 GAF domain GAF_2 PF13185.6 GAX19422.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 GAF domain DUF2660 PF10859.8 GAX19422.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) HisKA PF00512.25 GAX19422.1 - 0.12 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX19422.1 - 0.25 11.2 0.6 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2OG-FeII_Oxy_2 PF13532.6 GAX19423.1 - 8e-17 62.1 0.1 1.3e-16 61.4 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX19423.1 - 0.00056 20.3 0.0 0.00098 19.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Vps54_N PF10475.9 GAX19423.1 - 0.16 11.2 0.0 0.38 10.0 0.0 1.5 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Pre-PUA PF17832.1 GAX19424.1 - 7.4e-22 77.8 0.1 1e-21 77.4 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 GAX19424.1 - 5.5e-16 58.3 0.0 1.2e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 PUA domain Sulfate_transp PF00916.20 GAX19425.1 - 3.3e-25 88.7 15.2 5.3e-25 88.0 15.2 1.3 1 0 0 1 1 1 1 Sulfate permease family B277 PF17623.2 GAX19426.1 - 0.18 10.9 0.4 0.43 9.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function Aminotran_5 PF00266.19 GAX19427.1 - 2.3e-27 95.9 0.0 7.2e-27 94.3 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAX19427.1 - 0.0067 15.6 0.0 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II ATP_bind_3 PF01171.20 GAX19427.1 - 0.0088 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 PP-loop family Attractin PF08037.11 GAX19427.1 - 0.07 13.1 0.4 0.22 11.5 0.4 1.8 1 0 0 1 1 1 0 Attractin family Nucleoporin_N PF08801.11 GAX19428.1 - 6.5e-42 143.8 0.4 4.3e-25 88.4 0.0 2.5 2 1 0 2 2 2 2 Nup133 N terminal like Nucleoporin_C PF03177.14 GAX19428.1 - 8.8e-17 61.1 2.6 1.4e-16 60.4 2.6 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal BT1 PF03092.16 GAX19429.1 - 5.9e-31 107.3 18.5 1.7e-19 69.5 9.0 3.4 2 2 1 3 3 3 2 BT1 family PUCC PF03209.15 GAX19429.1 - 1.1e-10 41.1 0.2 1.1e-10 41.1 0.2 1.8 2 0 0 2 2 2 1 PUCC protein DUF3852 PF12963.7 GAX19429.1 - 0.044 14.1 0.3 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) Acyltransferase PF01553.21 GAX19430.1 - 6.1e-27 93.9 0.0 9.5e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase MS_channel PF00924.18 GAX19432.1 - 1.5e-25 89.9 0.0 2.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel MS_channel PF00924.18 GAX19433.1 - 2.5e-27 95.8 0.0 3.3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel VID27_PH PF17747.1 GAX19434.1 - 0.024 14.9 0.1 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 VID27 PH-like domain DUF2854 PF11016.8 GAX19435.1 - 1.1e-45 155.1 0.0 1.5e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) Peptidase_M43 PF05572.13 GAX19436.1 - 9.9e-16 58.0 0.1 1.3e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 GAX19436.1 - 4e-05 23.3 0.1 6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX19436.1 - 0.0009 19.4 0.2 0.0009 19.4 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 GAX19436.1 - 0.005 16.7 0.2 0.0093 15.8 0.2 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 GAX19436.1 - 0.0053 15.8 0.3 0.0071 15.3 0.3 1.2 1 0 0 1 1 1 1 Peptidase M66 DUF4953 PF16313.5 GAX19436.1 - 0.0082 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Met-zincin Reprolysin_3 PF13582.6 GAX19436.1 - 0.011 16.3 0.2 0.016 15.7 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX19436.1 - 0.012 15.5 0.1 0.012 15.5 0.1 1.2 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 GAX19436.1 - 0.025 13.2 0.2 0.033 12.8 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase family Surfac_D-trimer PF09006.11 GAX19436.1 - 0.06 13.2 0.3 0.094 12.6 0.3 1.3 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Peptidase_M54 PF07998.11 GAX19436.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 Pkinase PF00069.25 GAX19437.1 - 1.6e-31 109.6 0.0 5.6e-31 107.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19437.1 - 4.3e-27 95.0 0.0 6.1e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX19437.1 - 0.035 12.9 0.0 0.072 11.8 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Spc7 PF08317.11 GAX19440.1 - 0.28 10.0 13.4 0.69 8.7 13.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 GAX19440.1 - 0.34 11.0 5.0 0.62 10.1 5.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 GAX19440.1 - 1.2 8.2 13.4 2.4 7.2 13.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRP7 PF12923.7 GAX19441.1 - 1.5e-26 92.9 10.9 1.5e-26 92.9 10.9 2.1 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 GAX19441.1 - 8.5e-07 28.9 1.2 3.6e-06 26.9 0.0 2.4 2 1 0 2 2 2 1 Rrp7 RRM-like N-terminal domain Ribosomal_L14e PF01929.17 GAX19441.1 - 0.012 16.1 1.1 0.11 13.0 0.9 2.6 2 0 0 2 2 2 0 Ribosomal protein L14 DUF4347 PF14252.6 GAX19441.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Vps39_1 PF10366.9 GAX19441.1 - 0.38 11.1 3.5 0.21 11.9 1.1 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Pkinase PF00069.25 GAX19443.1 - 3.9e-27 95.3 0.0 1.1e-26 93.8 0.0 1.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19443.1 - 1.7e-24 86.5 0.0 2e-23 83.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase BMP2K_C PF15282.6 GAX19444.1 - 0.1 12.5 0.6 0.16 11.8 0.6 1.2 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus 7tm_4 PF13853.6 GAX19444.1 - 0.25 11.0 1.6 0.35 10.5 0.3 1.8 2 0 0 2 2 2 0 Olfactory receptor SET PF00856.28 GAX19445.1 - 4.2e-10 40.3 0.1 4.2e-05 24.0 0.0 3.9 3 1 0 3 3 3 2 SET domain SAF PF08666.12 GAX19445.1 - 0.094 13.4 0.0 42 4.9 0.0 3.4 3 0 0 3 3 3 0 SAF domain DnaJ-X PF14308.6 GAX19446.1 - 1.2e-32 113.1 0.2 1.2e-32 113.1 0.2 2.8 4 0 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAX19446.1 - 4.4e-22 78.0 4.5 5.6e-22 77.6 2.9 2.2 2 0 0 2 2 2 1 DnaJ domain ATG_C PF09333.11 GAX19446.1 - 8.1e-07 29.3 1.4 2.1e-06 28.0 0.2 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain TPR_2 PF07719.17 GAX19447.1 - 7.4e-07 28.8 10.2 0.012 15.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX19447.1 - 1.2e-06 28.1 4.0 0.00011 21.9 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX19447.1 - 9.7e-06 26.1 4.5 0.042 14.5 4.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX19447.1 - 1.1e-05 25.0 8.9 0.001 18.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX19447.1 - 4.7e-05 23.9 7.6 1.7 9.7 0.0 5.1 3 2 1 4 4 3 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GAX19447.1 - 0.00012 22.0 0.8 0.00012 22.0 0.8 3.0 4 0 0 4 4 4 1 Putative TPR-like repeat TPR_6 PF13174.6 GAX19447.1 - 0.00076 20.0 6.6 0.024 15.3 0.7 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1635 PF07795.11 GAX19447.1 - 0.0013 18.7 6.9 0.0013 18.7 6.9 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1635) TPR_12 PF13424.6 GAX19447.1 - 0.0017 18.6 8.6 0.55 10.6 0.1 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX19447.1 - 0.0066 16.6 8.0 0.14 12.5 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX19447.1 - 0.008 16.7 13.2 0.36 11.4 2.6 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat SRP72 PF08492.12 GAX19447.1 - 0.016 15.6 6.1 0.016 15.6 6.1 3.4 3 1 0 3 3 2 0 SRP72 RNA-binding domain MIT PF04212.18 GAX19447.1 - 0.017 15.2 2.1 2.1 8.5 0.0 3.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 GAX19447.1 - 0.023 14.9 13.5 0.86 9.9 1.2 4.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GAX19447.1 - 0.28 11.4 3.8 0.58 10.3 0.0 3.2 3 1 1 4 4 3 0 Tetratricopeptide repeat HemY_N PF07219.13 GAX19447.1 - 0.29 11.3 1.6 2.6 8.3 0.5 2.7 2 0 0 2 2 2 0 HemY protein N-terminus TPR_10 PF13374.6 GAX19447.1 - 0.32 10.9 5.3 1 9.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TraT PF05818.12 GAX19449.1 - 0.01 15.5 0.0 0.01 15.5 0.0 2.3 2 1 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF3439 PF11921.8 GAX19449.1 - 1.2 9.2 7.6 0.11 12.4 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4746 PF15928.5 GAX19449.1 - 2.3 7.6 6.9 4.2 6.7 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PrmA PF06325.13 GAX19450.1 - 8.1e-10 38.6 0.1 1.4e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX19450.1 - 9e-05 23.1 0.1 0.00048 20.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX19450.1 - 0.00077 19.0 0.1 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX19450.1 - 0.0016 18.2 0.0 0.0035 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX19450.1 - 0.0021 18.0 0.2 0.0041 17.1 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX19450.1 - 0.0023 17.8 0.0 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX19450.1 - 0.0025 18.4 0.0 0.0083 16.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAX19450.1 - 0.0063 17.5 0.0 0.016 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX19450.1 - 0.02 14.2 0.8 0.031 13.6 0.2 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 GAX19450.1 - 0.028 13.8 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 GAX19450.1 - 0.06 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GCD14 PF08704.10 GAX19450.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PRMT5 PF05185.16 GAX19450.1 - 0.094 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 GAX19450.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 GAX19450.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Coq4 PF05019.13 GAX19451.1 - 5.3e-68 228.7 0.0 6.4e-68 228.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GyrI-like PF06445.15 GAX19451.1 - 0.012 15.9 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 GyrI-like small molecule binding domain Pkinase PF00069.25 GAX19452.1 - 5e-33 114.6 0.0 4.3e-32 111.5 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19452.1 - 1.7e-29 102.9 0.0 9.7e-28 97.1 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase TPR_12 PF13424.6 GAX19453.1 - 2e-28 98.5 17.3 8.7e-11 42.0 0.1 6.5 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX19453.1 - 6.4e-23 79.6 10.0 0.00064 19.4 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX19453.1 - 7e-22 75.7 19.1 0.00085 19.3 0.8 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAX19453.1 - 7.7e-16 56.9 14.3 0.039 14.0 0.5 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAX19453.1 - 2.2e-13 49.6 17.3 0.022 14.6 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX19453.1 - 2.7e-11 42.7 11.1 0.012 15.8 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX19453.1 - 2.6e-10 39.8 7.3 0.0055 16.4 0.1 7.2 7 2 1 8 8 7 2 TPR repeat TPR_16 PF13432.6 GAX19453.1 - 7.9e-10 39.2 0.8 4.9e-06 27.1 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX19453.1 - 1.4e-08 34.6 9.6 2.3e-06 27.3 0.0 3.2 2 1 0 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 GAX19453.1 - 5.4e-06 26.7 3.9 24 5.8 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat SNAP PF14938.6 GAX19453.1 - 7.4e-06 25.6 3.1 0.024 14.1 0.0 3.5 3 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 GAX19453.1 - 2.6e-05 24.7 14.6 9.6 7.3 0.2 7.5 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX19453.1 - 4.8e-05 23.2 0.1 0.0042 16.8 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GAX19453.1 - 0.00017 21.7 4.2 0.76 10.0 1.4 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX19453.1 - 0.0015 17.8 3.9 0.12 11.6 0.0 3.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX19453.1 - 0.0074 16.8 11.8 1 9.9 0.2 5.4 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX19453.1 - 0.012 16.0 0.0 12 6.6 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX19453.1 - 0.014 15.5 1.1 9.2 6.4 0.1 3.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 GAX19453.1 - 0.021 14.9 9.4 0.48 10.5 0.2 5.2 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 GAX19453.1 - 0.026 14.0 0.2 14 5.2 0.2 3.9 3 0 0 3 3 3 0 SHNi-TPR LamB_YcsF PF03746.16 GAX19453.1 - 0.034 13.8 0.3 0.085 12.5 0.1 1.6 1 1 1 2 2 2 0 LamB/YcsF family DUF5344 PF17279.2 GAX19453.1 - 0.056 14.0 3.1 1.9 9.1 0.1 3.9 4 1 0 4 4 4 0 Family of unknown function (DUF5344) ComR_TPR PF18710.1 GAX19453.1 - 0.067 12.7 3.5 1.9 8.0 0.0 3.2 2 1 1 3 3 3 0 ComR tetratricopeptide Latarcin PF10279.9 GAX19453.1 - 0.08 13.3 0.1 5.7 7.4 0.1 3.0 1 1 0 1 1 1 0 Latarcin precursor ANAPC3 PF12895.7 GAX19453.1 - 0.082 13.1 8.5 5.1 7.4 0.1 4.8 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Lipoprotein_2 PF00921.17 GAX19453.1 - 0.091 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Borrelia lipoprotein ApbE PF02424.15 GAX19453.1 - 0.16 11.5 0.3 0.47 9.9 0.0 1.8 2 1 0 2 2 2 0 ApbE family TPR_20 PF14561.6 GAX19453.1 - 0.18 12.2 3.8 5 7.5 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Cas_DxTHG PF09455.10 GAX19453.1 - 0.3 10.6 5.0 0.85 9.1 4.7 1.8 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family E1-E2_ATPase PF00122.20 GAX19454.1 - 1.2e-47 161.8 7.2 1e-45 155.5 5.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX19454.1 - 5.7e-34 117.4 3.3 5.7e-34 117.4 3.3 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAX19454.1 - 3.8e-26 92.7 0.2 2e-20 74.0 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX19454.1 - 7.4e-17 60.8 0.1 7.4e-17 60.8 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAX19454.1 - 7.1e-16 58.1 0.0 3.5e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAX19454.1 - 0.00049 19.9 1.3 0.0024 17.7 1.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX19454.1 - 0.025 15.0 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 GAX19455.1 - 2.2e-50 171.6 46.1 1.9e-38 132.3 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX19455.1 - 7.5e-08 31.6 30.6 1.7e-05 23.9 14.5 3.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 GAX19455.1 - 1.4e-07 30.7 9.2 0.0011 17.9 2.6 3.0 2 1 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 GAX19455.1 - 1.8e-07 30.0 25.8 9.5e-06 24.3 16.0 2.7 1 1 1 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 GAX19455.1 - 7.9e-05 21.6 6.7 0.0024 16.7 2.3 2.5 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_4 PF06779.14 GAX19455.1 - 0.00011 21.7 9.6 0.00011 21.7 9.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 GAX19455.1 - 0.028 12.7 14.8 1.8 6.8 7.6 3.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family COX14 PF14880.6 GAX19456.1 - 0.07 13.0 0.6 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Globin PF00042.22 GAX19457.1 - 8.1e-09 36.0 0.0 2.9e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Globin Clat_adaptor_s PF01217.20 GAX19458.1 - 1.1e-50 171.2 4.0 1.7e-50 170.6 4.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Guanylate_cyc PF00211.20 GAX19459.1 - 2e-47 161.2 0.0 3.5e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX19459.1 - 9.1e-27 94.3 0.3 9.1e-27 94.3 0.3 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDZ_6 PF17820.1 GAX19459.1 - 3.6e-07 29.9 0.0 8.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX19459.1 - 1.6e-05 25.2 0.1 4.1e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain TMEM126 PF07114.11 GAX19459.1 - 0.084 12.3 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 126 GAF_2 PF13185.6 GAX19459.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 GAF domain PDZ_2 PF13180.6 GAX19459.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Arrestin_N PF00339.29 GAX19461.1 - 1.8e-05 24.9 0.0 0.0061 16.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Gp_dh_C PF02800.20 GAX19462.1 - 5.4e-57 191.8 0.1 8.2e-57 191.2 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX19462.1 - 3.3e-32 110.8 0.0 8e-32 109.6 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain adh_short PF00106.25 GAX19466.1 - 3.9e-32 111.3 0.7 2e-23 82.8 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX19466.1 - 1.3e-21 77.3 0.2 1.1e-14 54.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX19466.1 - 7.6e-07 29.2 1.7 1.6e-06 28.2 0.1 2.1 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 GAX19466.1 - 0.0016 18.0 0.1 0.0056 16.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAX19466.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_trans_1_2 PF13524.6 GAX19467.1 - 6.5e-11 42.5 0.0 1.7e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Galactosyl_T PF01762.21 GAX19467.1 - 0.085 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Galactosyltransferase Fringe PF02434.16 GAX19467.1 - 0.12 11.7 0.4 0.78 9.1 0.4 2.0 1 1 0 1 1 1 0 Fringe-like Glyco_trans_1_2 PF13524.6 GAX19468.1 - 8.9e-13 48.5 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 XH PF03469.14 GAX19470.1 - 0.12 12.3 1.3 8 6.4 0.4 2.3 2 0 0 2 2 2 0 XH domain Pkinase PF00069.25 GAX19471.1 - 1.4e-32 113.1 0.0 1.7e-31 109.6 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19471.1 - 2.9e-27 95.6 0.0 1.2e-26 93.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase zf-CW PF07496.15 GAX19472.1 - 4.7e-29 100.1 26.5 1.7e-16 60.0 8.9 2.6 2 0 0 2 2 2 2 CW-type Zinc Finger NTP_transf_2 PF01909.23 GAX19474.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Pollen_allerg_1 PF01357.21 GAX19475.1 - 0.0014 18.6 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.17 GAX19475.1 - 0.098 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Barwin family Pollen_allerg_1 PF01357.21 GAX19476.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Pollen allergen Barwin PF00967.17 GAX19477.1 - 0.0076 16.1 0.4 0.015 15.2 0.4 1.5 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.21 GAX19477.1 - 0.015 15.3 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 Pollen allergen Cerato-platanin PF07249.12 GAX19477.1 - 0.069 13.3 0.9 0.89 9.7 0.0 2.6 3 0 0 3 3 3 0 Cerato-platanin Isochorismatase PF00857.20 GAX19478.1 - 6.3e-18 65.6 0.0 1.1e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.6 GAX19478.1 - 0.0046 17.2 0.3 0.022 14.9 0.1 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FA_desaturase PF00487.24 GAX19479.1 - 1.8e-30 106.6 26.2 1.8e-30 106.6 26.2 2.5 3 0 0 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAX19479.1 - 4.4e-12 46.0 0.0 8.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3792 PF12670.7 GAX19479.1 - 0.32 11.2 7.7 14 5.8 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) WD40 PF00400.32 GAX19481.1 - 2.4e-08 34.5 5.1 0.00036 21.3 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 GAX19481.1 - 0.2 10.6 0.0 0.5 9.3 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region Ank PF00023.30 GAX19482.1 - 2.3e-06 27.8 1.0 0.094 13.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 GAX19482.1 - 4.2e-06 27.3 0.0 0.08 13.5 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19482.1 - 0.00073 20.1 0.7 0.27 11.8 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19482.1 - 0.0025 18.2 2.8 0.46 11.2 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat HSP70 PF00012.20 GAX19483.1 - 9.6e-77 258.5 7.1 9.6e-77 258.5 7.1 3.0 1 1 1 3 3 3 2 Hsp70 protein Methyltrn_RNA_4 PF09936.9 GAX19483.1 - 0.076 12.9 0.6 0.19 11.6 0.6 1.6 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase DUF563 PF04577.14 GAX19485.1 - 3.6e-19 69.8 0.2 6.2e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Gln-synt_N PF03951.19 GAX19485.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Me-amine-dh_L PF02975.14 GAX19486.1 - 6.7 7.3 8.9 4.1 7.9 0.1 4.1 4 0 0 4 4 4 0 Methylamine dehydrogenase, L chain PfkB PF00294.24 GAX19488.1 - 4.9e-70 236.2 6.5 6.4e-70 235.8 6.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Glyco_hydro_16 PF00722.21 GAX19489.1 - 5.8e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 O-FucT PF10250.9 GAX19490.1 - 8.1e-47 160.5 0.0 1.1e-46 160.1 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase eIF-3c_N PF05470.12 GAX19491.1 - 1e-138 463.3 34.0 1.7e-97 327.2 5.8 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 GAX19491.1 - 1.5e-10 41.5 0.0 3.9e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain FAS_N PF17828.1 GAX19491.1 - 0.009 16.0 1.0 0.33 11.0 0.5 2.6 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta DUF4195 PF13836.6 GAX19491.1 - 0.11 12.7 19.5 0.27 11.3 19.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) GEMIN8 PF15348.6 GAX19491.1 - 0.75 10.0 17.2 0.11 12.8 12.3 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 LRR_8 PF13855.6 GAX19492.1 - 2.3e-24 84.9 21.7 4.6e-07 29.5 3.2 5.9 3 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 GAX19492.1 - 1.1e-19 70.1 17.1 0.0019 18.5 0.1 6.8 3 1 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX19492.1 - 7.3e-08 31.9 14.0 3.4 8.6 0.0 10.0 13 0 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.6 GAX19492.1 - 0.34 11.1 22.2 37 4.7 0.0 8.4 10 0 0 10 10 10 0 Leucine Rich repeat LRR_8 PF13855.6 GAX19493.1 - 0.00015 21.5 3.5 0.044 13.6 0.6 3.6 3 1 1 4 4 4 2 Leucine rich repeat GIT_CC PF16559.5 GAX19493.1 - 0.0002 21.2 1.9 0.00051 19.8 1.9 1.7 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Fungal_TACC PF12709.7 GAX19493.1 - 0.00035 21.0 0.7 0.00069 20.0 0.7 1.4 1 0 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_1 PF00170.21 GAX19493.1 - 0.0071 16.4 2.4 0.015 15.4 2.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor Cep57_CLD_2 PF14197.6 GAX19493.1 - 0.015 15.4 0.1 0.041 14.0 0.1 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ADIP PF11559.8 GAX19493.1 - 0.029 14.5 2.3 0.06 13.4 2.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 GAX19493.1 - 0.038 13.4 2.0 0.062 12.7 2.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 GAX19493.1 - 0.052 14.0 1.1 0.11 13.0 1.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF3450 PF11932.8 GAX19493.1 - 0.054 12.8 2.3 0.087 12.1 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 GAX19493.1 - 0.081 13.4 1.7 0.15 12.5 1.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4200 PF13863.6 GAX19493.1 - 0.11 12.9 1.3 0.24 11.8 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 GAX19493.1 - 0.31 11.5 1.6 0.59 10.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DivIC PF04977.15 GAX19493.1 - 0.73 9.6 3.1 0.75 9.6 1.7 1.7 1 1 0 1 1 1 0 Septum formation initiator LRR_4 PF12799.7 GAX19493.1 - 1.4 9.4 4.0 51 4.5 0.0 3.7 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) Pep1_7 PF17232.2 GAX19494.1 - 0.051 14.0 1.5 5.2 7.6 0.1 2.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 DUF817 PF05675.12 GAX19495.1 - 0.032 13.9 1.8 0.059 13.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF817) SesA PF17107.5 GAX19496.1 - 0.052 13.7 1.4 0.12 12.6 1.4 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases GIT_CC PF16559.5 GAX19496.1 - 0.13 12.1 2.1 0.38 10.7 2.1 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 GAX19496.1 - 1.6 8.5 4.7 9.5 6.1 1.1 2.5 2 1 0 2 2 2 0 Septum formation initiator Rab3-GTPase_cat PF13890.6 GAX19497.1 - 8.3e-39 132.8 0.2 3.6e-38 130.8 0.0 2.3 3 0 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit AAA_16 PF13191.6 GAX19498.1 - 0.0064 16.9 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain Guanylate_kin PF00625.21 GAX19498.1 - 0.18 11.5 0.6 9.1 5.9 0.0 2.4 2 1 0 2 2 2 0 Guanylate kinase Methyltransf_32 PF13679.6 GAX19499.1 - 2.9e-05 24.1 0.1 8.6e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF2208 PF09973.9 GAX19500.1 - 0.00054 19.6 0.3 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2208) Gaa1 PF04114.14 GAX19500.1 - 0.0058 15.7 3.3 0.66 8.9 0.3 2.1 2 0 0 2 2 2 2 Gaa1-like, GPI transamidase component TctB PF07331.11 GAX19500.1 - 0.0093 16.2 3.2 0.0093 16.2 3.2 2.1 3 0 0 3 3 3 1 Tripartite tricarboxylate transporter TctB family HATPase_c PF02518.26 GAX19500.1 - 0.01 16.4 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rdx PF10262.9 GAX19501.1 - 0.017 15.3 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 Rdx family Transketolase_N PF00456.21 GAX19502.1 - 1.1e-146 488.0 0.0 3.1e-146 486.6 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAX19502.1 - 2.4e-38 131.6 0.0 1.1e-37 129.4 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX19502.1 - 9.3e-09 35.2 0.0 3e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAX19502.1 - 0.0016 17.7 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Terpene_synth PF01397.21 GAX19502.1 - 0.067 12.9 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain DUF1295 PF06966.12 GAX19503.1 - 2.5e-22 79.6 0.1 4.2e-22 78.8 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 GAX19503.1 - 4.9e-05 23.7 0.4 0.00022 21.6 0.1 2.3 1 1 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 GAX19503.1 - 0.0019 18.2 0.2 0.0031 17.5 0.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 GAX19503.1 - 0.0027 18.1 0.1 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2975 PF11188.8 GAX19503.1 - 0.26 11.2 2.1 0.36 10.7 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Pkinase PF00069.25 GAX19504.1 - 3.6e-45 154.4 0.0 1.2e-25 90.4 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19504.1 - 1.1e-17 64.2 0.6 9.7e-15 54.5 0.0 3.2 4 0 0 4 4 4 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAX19504.1 - 0.033 13.2 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UQ_con PF00179.26 GAX19505.1 - 8.5e-52 174.5 0.0 9.5e-52 174.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX19505.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 GAX19505.1 - 0.025 14.9 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 GAX19505.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain Octopine_DH PF02317.17 GAX19506.1 - 3.5e-33 114.8 0.0 6e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.17 GAX19506.1 - 0.0022 18.5 0.8 0.015 15.9 0.8 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAX19506.1 - 0.0028 17.0 0.0 0.0081 15.5 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAX19506.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 GAX19506.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TetR_N PF00440.23 GAX19506.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Epimerase PF01370.21 GAX19507.1 - 2.7e-55 187.5 0.0 3.8e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX19507.1 - 1.2e-16 61.0 0.0 2.6e-16 60.0 0.0 1.3 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX19507.1 - 2.8e-06 26.7 1.0 7.6e-06 25.3 0.0 1.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX19507.1 - 0.00019 20.6 0.0 0.00041 19.5 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX19507.1 - 0.064 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein DUF5561 PF17716.1 GAX19507.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5561) BRO1 PF03097.18 GAX19509.1 - 3.9e-49 167.5 1.3 4.4e-49 167.3 1.3 1.1 1 0 0 1 1 1 1 BRO1-like domain Cys_rich_FGFR PF00839.17 GAX19509.1 - 0.84 9.9 5.5 1.2 9.4 0.0 3.2 4 0 0 4 4 4 0 Cysteine rich repeat GDP_Man_Dehyd PF16363.5 GAX19510.1 - 9.6e-62 209.3 0.0 2.8e-61 207.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX19510.1 - 2.3e-55 187.7 0.0 2.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX19510.1 - 3.4e-18 65.6 0.0 5.1e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAX19510.1 - 3.2e-15 56.0 0.0 2.9e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX19510.1 - 3.2e-12 46.2 0.0 4.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX19510.1 - 1.1e-09 37.9 0.0 1.9e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 GAX19510.1 - 6.4e-06 26.2 0.0 9.2e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 GAX19510.1 - 0.00017 21.1 0.0 0.0086 15.6 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GAX19510.1 - 0.001 19.0 0.0 0.0048 16.8 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox PF00070.27 GAX19510.1 - 0.017 15.7 0.1 0.033 14.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAX19510.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAX19510.1 - 0.11 12.8 0.0 0.39 11.0 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 GAX19510.1 - 0.14 11.7 0.0 1.2 8.6 0.0 2.3 3 0 0 3 3 3 0 NmrA-like family GFO_IDH_MocA PF01408.22 GAX19511.1 - 0.11 13.4 0.1 0.19 12.6 0.1 1.6 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pardaxin PF07425.11 GAX19513.1 - 0.28 10.8 1.9 2.1 8.1 0.5 2.5 2 0 0 2 2 2 0 Pardaxin Glyco_transf_20 PF00982.21 GAX19516.1 - 1.3e-98 330.7 0.0 2.4e-98 329.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAX19516.1 - 1e-28 100.1 0.0 2.2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase HC2 PF07382.11 GAX19517.1 - 0.18 11.9 26.9 0.43 10.6 26.9 1.6 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 PhzC-PhzF PF02567.16 GAX19517.1 - 7 6.0 9.0 1.1 8.6 1.8 2.2 1 1 1 2 2 2 0 Phenazine biosynthesis-like protein CENP-N PF05238.13 GAX19518.1 - 0.33 10.2 8.5 0.054 12.8 2.7 2.1 1 1 1 2 2 2 0 Kinetochore protein CHL4 like HATPase_c PF02518.26 GAX19519.1 - 6e-29 100.8 0.1 1.1e-28 99.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX19519.1 - 6e-21 74.7 1.8 1.1e-20 73.9 0.3 2.3 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 GAX19519.1 - 4.7e-16 58.6 0.0 2e-15 56.6 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Parvo_NS1 PF01057.17 GAX19519.1 - 0.0081 15.3 0.1 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Methyltr_RsmB-F PF01189.17 GAX19519.1 - 0.038 13.6 0.4 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PAS_4 PF08448.10 GAX19519.1 - 0.079 13.2 0.1 13 6.1 0.0 2.6 2 0 0 2 2 2 0 PAS fold PAS_8 PF13188.7 GAX19519.1 - 0.11 12.5 0.0 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 PAS domain SUI1 PF01253.22 GAX19520.1 - 1.5e-15 57.5 0.1 3.6e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.18 GAX19520.1 - 0.00025 20.9 0.1 0.00053 19.8 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain PUA PF01472.20 GAX19520.1 - 0.0023 17.8 0.0 0.0078 16.2 0.0 1.9 1 0 0 1 1 1 1 PUA domain NAD_binding_1 PF00175.21 GAX19521.1 - 1.7e-21 76.9 0.0 3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX19521.1 - 2.8e-17 62.9 0.0 4.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAX19521.1 - 0.032 14.4 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain HSF_DNA-bind PF00447.17 GAX19522.1 - 1.7e-20 73.4 0.0 3.3e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding NAD_binding_8 PF13450.6 GAX19523.1 - 5e-12 45.9 0.0 9.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX19523.1 - 6.8e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX19523.1 - 4.2e-05 22.4 0.0 0.00086 18.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 GAX19523.1 - 7.7e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAX19523.1 - 0.00042 19.7 0.0 0.0011 18.4 0.0 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAX19523.1 - 0.00097 18.3 0.0 0.0038 16.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GAX19523.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GAX19523.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAX19523.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 GAX19523.1 - 0.059 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAX19523.1 - 0.079 13.5 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX19523.1 - 0.25 10.4 0.1 0.36 9.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CxC7 PF18866.1 GAX19524.1 - 0.0056 16.8 2.3 0.016 15.3 0.2 2.2 2 0 0 2 2 2 1 CxC7 like cysteine cluster associated with KDZ transposases PT PF04886.12 GAX19524.1 - 0.0076 15.8 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 PT repeat Peptidase_C11 PF03415.14 GAX19525.1 - 2e-30 106.4 0.2 3.1e-30 105.8 0.1 1.3 1 1 0 1 1 1 1 Clostripain family PT PF04886.12 GAX19526.1 - 1.3e-06 27.8 70.7 0.11 12.0 2.1 9.1 7 3 0 7 7 7 7 PT repeat Rhodanese PF00581.20 GAX19527.1 - 0.00026 21.5 0.0 0.00054 20.4 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain DLH PF01738.18 GAX19528.1 - 2.2e-30 105.8 0.0 3.6e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX19528.1 - 0.0034 16.9 0.0 0.0092 15.5 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1100 PF06500.11 GAX19528.1 - 0.021 13.6 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) GT87 PF09594.10 GAX19528.1 - 0.058 13.1 0.3 0.84 9.3 0.2 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 87 AXE1 PF05448.12 GAX19528.1 - 0.08 11.6 0.0 0.14 10.8 0.0 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF285 PF03382.14 GAX19528.1 - 0.19 11.5 0.6 1 9.1 0.1 2.1 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 RAP PF08373.10 GAX19530.1 - 9.3e-14 51.3 0.0 2.8e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 RAP domain FAST_1 PF06743.15 GAX19530.1 - 5.8e-08 32.6 7.0 1.3 9.0 0.0 8.0 7 3 3 10 10 10 4 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 GAX19530.1 - 0.039 14.1 1.1 33 4.8 0.0 4.0 4 0 0 4 4 4 0 REase_MTES_1575 HMG_box PF00505.19 GAX19531.1 - 1.3e-10 41.6 5.9 7.7e-08 32.7 2.6 2.9 2 1 1 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX19531.1 - 4.7e-07 30.3 4.9 4.1e-05 24.1 2.0 2.5 1 1 1 2 2 2 2 HMG-box domain YABBY PF04690.13 GAX19531.1 - 0.017 15.7 0.4 0.043 14.4 0.0 2.0 1 1 1 2 2 2 0 YABBY protein HMG_box_5 PF14887.6 GAX19531.1 - 0.059 13.3 2.9 0.066 13.2 0.8 2.0 1 1 1 2 2 2 0 HMG (high mobility group) box 5 HEPN_Swt1 PF18731.1 GAX19531.1 - 0.28 11.6 6.1 0.53 10.6 3.9 2.4 2 1 0 2 2 2 0 Swt1-like HEPN AAA_21 PF13304.6 GAX19531.1 - 0.34 10.7 7.0 0.18 11.6 3.9 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AF-4 PF05110.13 GAX19533.1 - 1.4 6.9 40.4 1.8 6.6 40.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC45 PF02724.14 GAX19533.1 - 2.5 6.3 19.6 4.4 5.5 19.6 1.5 1 0 0 1 1 1 0 CDC45-like protein MAGE PF01454.19 GAX19535.1 - 1.3e-25 90.4 0.0 2.1e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 MAGE family GTP_EFTU PF00009.27 GAX19536.1 - 9.6e-53 178.6 0.1 1.5e-52 178.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 GAX19536.1 - 4.1e-27 94.5 0.0 9.9e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 GAX19536.1 - 4.3e-21 74.7 0.0 1.1e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX19536.1 - 1e-10 41.9 0.1 1.9e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX19536.1 - 1.5e-05 25.1 0.0 3.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 GAX19536.1 - 0.0011 19.0 0.0 0.0041 17.2 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 GAX19536.1 - 0.0017 18.0 0.1 0.0052 16.4 0.0 1.8 2 0 0 2 2 2 1 Ras family RF3_C PF16658.5 GAX19536.1 - 0.0066 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 GAX19536.1 - 0.0073 15.7 0.1 0.16 11.4 0.0 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 GAX19536.1 - 0.11 12.5 0.1 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 GAX19536.1 - 0.2 11.9 0.0 0.98 9.6 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sel1 PF08238.12 GAX19537.1 - 1.4e-16 60.6 21.7 0.013 16.2 1.9 9.5 9 0 0 9 9 9 7 Sel1 repeat Choline_kinase PF01633.20 GAX19539.1 - 1.2e-44 152.4 0.0 2e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAX19539.1 - 2.8e-12 47.1 1.5 6.1e-12 46.0 1.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAX19539.1 - 0.0024 17.3 0.1 0.0042 16.4 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 GAX19539.1 - 0.027 13.9 0.1 0.076 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 GAX19539.1 - 0.032 13.6 0.1 0.08 12.3 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2777 PF10949.8 GAX19539.1 - 0.083 12.6 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) DUF1995 PF09353.10 GAX19540.1 - 1.7e-20 73.9 0.0 2.2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Glyco_tranf_2_4 PF13704.6 GAX19541.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2606 PF10794.9 GAX19541.1 - 0.22 11.3 1.1 1 9.2 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2606) PPR_2 PF13041.6 GAX19542.1 - 1.1e-49 166.4 0.0 2.4e-08 34.1 0.0 9.4 7 2 2 9 9 9 8 PPR repeat family PPR_3 PF13812.6 GAX19542.1 - 2.4e-41 139.6 0.0 2e-08 34.2 0.0 6.9 5 2 1 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.20 GAX19542.1 - 4.2e-40 133.2 3.9 8.3e-05 22.6 0.0 11.9 13 0 0 13 13 12 8 PPR repeat PPR_1 PF12854.7 GAX19542.1 - 6.8e-33 112.1 14.4 1.5e-07 31.0 0.0 10.9 10 1 1 11 11 11 7 PPR repeat PPR_long PF17177.4 GAX19542.1 - 5.7e-20 71.6 0.4 7.6e-09 35.2 0.0 4.9 2 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GAX19542.1 - 0.006 17.3 18.8 0.12 13.3 2.6 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat Gal11_ABD1 PF18535.1 GAX19542.1 - 0.009 16.1 0.1 1.6 8.9 0.0 3.1 3 0 0 3 3 3 1 Gal11 activator-binding domain (ABD1) BTAD PF03704.17 GAX19542.1 - 0.079 13.4 6.6 0.14 12.6 1.5 3.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TetR_C_7 PF14246.6 GAX19542.1 - 0.15 12.1 0.6 0.46 10.5 0.6 1.9 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain TPR_4 PF07721.14 GAX19542.1 - 2.2 9.2 14.6 6.4 7.7 1.4 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX19542.1 - 2.5 8.7 12.1 12 6.4 0.0 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX19542.1 - 8.6 6.7 9.4 19 5.6 0.3 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C65 PF10275.9 GAX19543.1 - 2.8e-61 207.1 0.0 3.3e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 GAX19543.1 - 0.0032 18.0 0.1 0.26 11.8 0.1 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease TMEM223 PF14640.6 GAX19544.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 Cadherin_C_2 PF16492.5 GAX19544.1 - 0.066 14.0 0.0 28 5.6 0.0 2.7 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal PT PF04886.12 GAX19546.1 - 2.3e-05 23.8 44.7 0.0012 18.4 1.7 6.0 5 1 1 6 6 6 4 PT repeat CDC45 PF02724.14 GAX19546.1 - 0.11 10.7 0.2 0.16 10.2 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Planc_extracel PF07595.12 GAX19546.1 - 0.23 11.3 5.7 0.065 13.0 2.4 1.9 2 0 0 2 2 2 0 Planctomycete extracellular Remorin_C PF03763.13 GAX19547.1 - 0.005 16.7 1.5 0.005 16.7 1.5 2.3 2 0 0 2 2 2 1 Remorin, C-terminal region DUF4284 PF14112.6 GAX19547.1 - 0.059 14.3 0.0 0.1 13.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 22 Complex1_LYR PF05347.15 GAX19548.1 - 0.00029 20.8 0.1 0.00049 20.1 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF924 PF06041.11 GAX19548.1 - 0.048 13.8 0.1 0.065 13.4 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) UBA PF00627.31 GAX19549.1 - 1.3e-06 28.1 0.2 1.3e-06 28.1 0.2 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Peptidase_C21 PF05381.12 GAX19549.1 - 0.022 15.1 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Tymovirus endopeptidase UBA_4 PF14555.6 GAX19549.1 - 0.073 12.9 0.2 0.24 11.3 0.2 1.9 1 1 0 1 1 1 0 UBA-like domain HSF_DNA-bind PF00447.17 GAX19550.1 - 1.3e-19 70.6 0.2 2.3e-19 69.8 0.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding MFS_1 PF07690.16 GAX19551.1 - 1.2e-32 113.3 20.3 1.9e-32 112.5 20.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX19551.1 - 2.3e-06 26.8 6.7 2.3e-06 26.8 6.7 1.8 1 1 0 2 2 2 1 Sugar (and other) transporter Myb_DNA-binding PF00249.31 GAX19552.1 - 1.8e-08 34.4 1.9 8.6e-08 32.3 0.7 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX19552.1 - 2.2e-05 24.6 1.1 0.0012 19.1 0.5 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GAX19552.1 - 0.0024 18.2 0.7 0.0024 18.2 0.7 3.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GAX19552.1 - 0.013 15.5 0.5 0.013 15.5 0.5 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ORC6 PF05460.13 GAX19552.1 - 3.7 6.7 10.4 2.5 7.3 7.4 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) S1 PF00575.23 GAX19553.1 - 1.8e-14 53.8 1.4 5.4e-14 52.3 1.4 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Presenilin PF01080.17 GAX19553.1 - 1.5 7.5 19.3 2.2 7.0 19.3 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 GAX19553.1 - 2 6.9 20.2 2.5 6.5 20.2 1.1 1 0 0 1 1 1 0 Macoilin family PNISR PF15996.5 GAX19553.1 - 3.2 8.0 23.4 6.4 7.0 23.4 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR LRR_8 PF13855.6 GAX19557.1 - 2.3e-14 52.9 16.5 0.0052 16.5 0.2 5.9 3 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 GAX19557.1 - 1.1e-12 47.9 19.9 0.015 15.7 1.1 7.0 5 1 3 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX19557.1 - 1.1e-05 25.3 14.7 13 6.8 0.2 9.2 11 0 0 11 11 11 1 Leucine Rich Repeat LRRNT_2 PF08263.12 GAX19557.1 - 0.0019 18.4 6.4 0.003 17.8 3.5 2.7 2 1 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 GAX19557.1 - 0.074 12.5 0.4 10 5.6 0.0 2.6 3 0 0 3 3 3 0 Leucine-rich repeat LRR_4 PF12799.7 GAX19558.1 - 1.1e-13 51.1 18.1 0.00031 21.1 0.1 6.9 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX19558.1 - 2.6e-12 46.3 15.5 0.0007 19.3 0.2 6.3 3 2 2 7 7 7 4 Leucine rich repeat LRR_1 PF00560.33 GAX19558.1 - 1.9e-05 24.6 4.2 30 5.7 0.1 7.5 9 0 0 9 9 9 1 Leucine Rich Repeat DUF3272 PF11676.8 GAX19558.1 - 0.03 14.6 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) LRRNT_2 PF08263.12 GAX19558.1 - 4.3 7.7 7.9 0.85 10.0 3.6 2.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Hus1 PF04005.12 GAX19559.1 - 1.4e-24 86.8 0.0 9.2e-24 84.1 0.0 1.9 1 1 0 1 1 1 1 Hus1-like protein LRR_8 PF13855.6 GAX19560.1 - 8.2e-22 76.7 27.6 0.00016 21.4 0.1 6.8 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX19560.1 - 2.9e-12 46.6 23.1 0.00072 19.9 0.5 6.5 6 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX19560.1 - 0.0038 17.5 0.8 0.01 16.1 0.8 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GAX19560.1 - 0.07 13.7 22.8 4.8 8.1 0.0 8.9 11 1 1 12 12 12 0 Leucine Rich Repeat Gar1 PF04410.14 GAX19561.1 - 1.2e-28 99.9 0.0 1.4e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glycos_transf_1 PF00534.20 GAX19562.1 - 1.8e-31 109.0 0.0 3e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX19562.1 - 2.6e-13 50.3 0.1 6.2e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAX19562.1 - 1.4e-12 48.2 0.0 2.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAX19562.1 - 2.4e-07 31.3 1.3 6e-07 30.0 1.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX19562.1 - 3.6e-05 24.1 0.0 7.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Carboxyl_trans PF01039.22 GAX19563.1 - 8.8e-161 535.9 0.0 1.6e-160 535.0 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain ACC_central PF08326.12 GAX19563.1 - 5.5e-71 239.8 0.0 2.8e-68 230.8 0.0 3.0 1 1 1 2 2 2 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 GAX19563.1 - 3.2e-50 170.6 0.1 8e-50 169.3 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAX19563.1 - 1e-29 103.3 0.0 2.7e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAX19563.1 - 7e-23 80.8 0.0 1.7e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAX19563.1 - 6.2e-12 45.2 0.0 2.3e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 GAX19563.1 - 5.9e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 GAX19563.1 - 4.1e-05 23.2 0.0 9.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PNK3P PF08645.11 GAX19563.1 - 0.014 15.1 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Biotin_lipoyl_2 PF13533.6 GAX19563.1 - 0.033 14.0 0.0 0.95 9.3 0.0 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like Vac14_Fig4_bd PF11916.8 GAX19563.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding FAD_binding_4 PF01565.23 GAX19563.1 - 0.075 12.8 0.0 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain DUF3182 PF11379.8 GAX19563.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Phage_GP20 PF06810.11 GAX19563.1 - 0.99 9.2 4.0 2.1 8.1 0.0 3.2 4 0 0 4 4 4 0 Phage minor structural protein GP20 Hist_deacetyl PF00850.19 GAX19564.1 - 2.3e-61 207.9 0.0 4.1e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.7 GAX19564.1 - 8.7e-22 77.5 0.2 6.2e-07 29.9 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19564.1 - 4.9e-20 71.6 0.6 6e-05 23.5 0.0 5.9 4 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX19564.1 - 8.6e-20 70.5 1.3 1.6e-07 31.4 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX19564.1 - 1.4e-15 56.9 6.0 2.6e-06 27.6 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 GAX19564.1 - 1.4e-12 46.5 1.6 0.00031 20.9 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Kinesin PF00225.23 GAX19565.1 - 5.6e-98 327.9 0.0 5.6e-98 327.9 0.0 3.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAX19565.1 - 5.4e-20 71.8 0.5 6.2e-19 68.4 0.0 3.2 2 0 0 2 2 2 1 Microtubule binding GAS PF13851.6 GAX19565.1 - 0.0032 16.9 20.5 0.0032 16.9 20.5 15.1 2 1 11 15 15 15 4 Growth-arrest specific micro-tubule binding AIM24 PF01987.17 GAX19566.1 - 2.1e-38 132.2 0.1 2.5e-38 131.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Hexapep PF00132.24 GAX19567.1 - 5.9e-09 35.3 0.8 0.0014 18.3 0.2 4.6 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAX19567.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.5 1 1 0 1 1 1 1 L-fucokinase GTP_EFTU_D4 PF14578.6 GAX19567.1 - 0.037 13.9 0.2 0.081 12.8 0.1 1.6 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AIM24 PF01987.17 GAX19568.1 - 3.3e-46 157.6 1.4 3.9e-46 157.4 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 GAX19569.1 - 9.7e-41 139.8 0.0 1.1e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Prot_ATP_ID_OB PF16450.5 GAX19569.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain zf-rbx1 PF12678.7 GAX19570.1 - 4.4e-22 78.1 2.4 6.8e-22 77.5 2.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAX19570.1 - 3.4e-16 59.1 4.5 5.3e-16 58.5 4.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 GAX19570.1 - 2.3e-10 40.6 6.9 2e-09 37.6 6.9 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX19570.1 - 2.8e-10 39.9 2.7 1.9e-08 34.0 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX19570.1 - 4.5e-08 32.8 2.3 8.7e-08 31.9 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX19570.1 - 7.4e-08 32.3 0.7 1.7e-07 31.1 0.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX19570.1 - 1.2e-06 28.4 2.4 2.7e-06 27.2 2.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAX19570.1 - 2.4e-06 27.3 3.4 1.1e-05 25.2 0.3 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAX19570.1 - 3e-06 27.0 2.2 5.7e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX19570.1 - 1.6e-05 24.6 2.2 0.00036 20.2 0.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAX19570.1 - 7.8e-05 22.2 1.2 7.8e-05 22.2 1.2 2.1 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 GAX19570.1 - 0.00039 20.5 4.0 0.0027 17.8 1.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zinc_ribbon_16 PF17034.5 GAX19570.1 - 0.00089 19.5 3.4 0.0063 16.7 3.4 2.0 1 1 0 1 1 1 1 Zinc-ribbon like family zf-Nse PF11789.8 GAX19570.1 - 0.0028 17.4 0.2 0.005 16.6 0.2 1.4 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 GAX19570.1 - 0.0033 17.2 2.7 0.0036 17.1 0.1 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 GAX19570.1 - 0.0091 16.0 4.1 0.029 14.4 1.6 2.4 2 1 0 2 2 2 1 Zinc-finger TerY_C PF15616.6 GAX19570.1 - 0.011 15.8 1.1 0.014 15.5 0.1 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING-like PF08746.11 GAX19570.1 - 0.014 15.7 1.3 0.014 15.7 1.3 1.8 2 0 0 2 2 2 0 RING-like domain Rtf2 PF04641.12 GAX19570.1 - 0.016 14.6 1.3 0.024 14.0 0.1 1.7 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_10 PF16685.5 GAX19570.1 - 0.051 13.7 0.7 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Baculo_RING PF05883.11 GAX19570.1 - 0.069 13.1 1.8 0.25 11.3 1.8 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.7 GAX19570.1 - 0.1 12.8 2.2 0.1 12.8 2.2 2.3 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 GAX19570.1 - 0.89 9.8 7.5 7.8 6.8 7.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Methyltransf_4 PF02390.17 GAX19571.1 - 8.9e-08 31.8 0.0 1.3e-06 28.0 0.0 2.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 GAX19571.1 - 0.00038 20.3 0.0 0.0019 18.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX19571.1 - 0.00076 20.1 0.1 0.0034 18.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX19571.1 - 0.032 14.2 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain UAE_UbL PF14732.6 GAX19571.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Methyltransf_23 PF13489.6 GAX19571.1 - 0.11 12.3 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain IKI3 PF04762.12 GAX19572.1 - 4.9e-148 494.8 0.0 1.2e-140 470.3 0.0 2.1 1 1 1 2 2 2 2 IKI3 family SR-25 PF10500.9 GAX19572.1 - 0.05 13.2 2.2 0.084 12.5 2.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC24_OB1 PF17246.2 GAX19575.1 - 0.13 12.3 3.0 0.8 9.8 3.0 2.2 1 1 0 1 1 1 0 Cell division control protein 24, OB domain 1 SUIM_assoc PF16619.5 GAX19575.1 - 0.4 10.8 0.0 0.4 10.8 0.0 4.6 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 GAX19575.1 - 0.67 9.9 45.5 0.021 14.8 28.2 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.31 GAX19576.1 - 3.4e-14 52.7 1.0 7.3e-14 51.7 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 GAX19576.1 - 8.5e-05 22.3 19.1 0.053 13.2 14.5 3.6 3 1 0 3 3 3 2 Transmembrane Fragile-X-F protein Phospholamban PF04272.14 GAX19576.1 - 0.064 12.7 0.0 0.064 12.7 0.0 2.4 3 0 0 3 3 3 0 Phospholamban Chloroa_b-bind PF00504.21 GAX19577.1 - 2.1e-31 109.6 0.2 3e-31 109.1 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pollen_allerg_1 PF01357.21 GAX19578.1 - 0.08 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Pollen allergen DUF5421 PF17458.2 GAX19580.1 - 0.055 12.9 0.2 0.72 9.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5421) T2SSF PF00482.23 GAX19580.1 - 0.087 12.8 0.1 0.67 9.9 0.0 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F PgaD PF13994.6 GAX19580.1 - 0.13 12.3 0.0 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 PgaD-like protein MHB PF16525.5 GAX19580.1 - 0.24 11.7 3.5 0.65 10.3 0.3 2.5 2 0 0 2 2 2 0 Haemophore, haem-binding DMPK_coil PF08826.10 GAX19580.1 - 1.2 9.3 6.1 0.21 11.7 1.8 1.9 2 0 0 2 2 2 0 DMPK coiled coil domain like Thioredoxin PF00085.20 GAX19581.1 - 4.6e-10 39.4 0.0 6.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX19581.1 - 0.13 12.6 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like MFS_1 PF07690.16 GAX19583.1 - 8.6e-22 77.5 17.8 8.6e-22 77.5 17.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily AP3D1 PF06375.11 GAX19584.1 - 0.05 13.8 7.0 0.065 13.5 7.0 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 GAX19584.1 - 3.1 7.8 7.3 4 7.5 7.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NAD_binding_10 PF13460.6 GAX19585.1 - 7.2e-24 84.7 0.0 1.5e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX19585.1 - 9e-14 51.6 0.0 3.1e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAX19585.1 - 1.4e-11 44.3 0.0 2.6e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAX19585.1 - 2.1e-09 37.2 0.1 3.1e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX19585.1 - 2.2e-08 33.9 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 GAX19585.1 - 1.8e-06 27.6 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 GAX19585.1 - 5e-06 26.5 0.0 8.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 GAX19585.1 - 9.5e-05 21.5 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAX19585.1 - 0.043 12.9 0.0 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX19585.1 - 0.066 12.4 0.0 0.2 10.8 0.0 1.9 1 1 1 2 2 2 0 Male sterility protein UQ_con PF00179.26 GAX19587.1 - 5.6e-10 39.0 0.0 8.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX19587.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Topoisom_bac PF01131.20 GAX19589.1 - 9.9e-101 337.7 0.0 3.2e-92 309.7 0.0 2.3 2 0 0 2 2 2 2 DNA topoisomerase HMG_box PF00505.19 GAX19589.1 - 9e-40 134.9 5.1 4.9e-13 49.3 0.2 4.0 4 0 0 4 4 4 3 HMG (high mobility group) box Toprim_C_rpt PF13368.6 GAX19589.1 - 2.4e-29 101.1 0.3 7.9e-08 32.2 0.1 5.2 4 1 0 4 4 4 4 Topoisomerase C-terminal repeat HMG_box_2 PF09011.10 GAX19589.1 - 1.7e-25 89.4 7.6 1.1e-07 32.4 0.2 3.6 3 0 0 3 3 3 3 HMG-box domain Toprim PF01751.22 GAX19589.1 - 4.9e-23 81.3 0.0 1.2e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 GAX19589.1 - 0.0016 18.9 0.0 0.0038 17.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain MarR_2 PF12802.7 GAX19589.1 - 0.0056 16.5 0.1 0.022 14.6 0.1 2.0 1 0 0 1 1 1 1 MarR family DUF4107 PF13389.6 GAX19589.1 - 0.032 14.4 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) NuA4 PF09340.10 GAX19590.1 - 7.6e-10 38.5 0.1 2.8e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 AATF-Che1 PF13339.6 GAX19590.1 - 0.26 12.0 4.5 2.9 8.6 3.5 2.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor UAA PF08449.11 GAX19591.1 - 3.1e-48 164.6 15.8 7e-48 163.4 15.8 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX19591.1 - 7.2e-07 29.4 21.1 4.8e-06 26.8 11.6 2.6 2 1 1 3 3 3 2 EamA-like transporter family Glyco_trans_1_2 PF13524.6 GAX19593.1 - 1.3e-14 54.3 0.0 3.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_11 PF08241.12 GAX19593.1 - 0.00048 20.7 0.0 0.0013 19.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX19593.1 - 0.00048 20.0 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX19593.1 - 0.0042 17.8 0.0 0.017 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 GAX19593.1 - 0.033 13.6 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.14 GAX19593.1 - 0.037 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ELMO_CED12 PF04727.13 GAX19596.1 - 9.6e-13 48.6 0.0 1.7e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Chloroa_b-bind PF00504.21 GAX19597.1 - 0.00017 22.2 0.1 0.00034 21.2 0.1 1.6 1 1 0 1 1 1 1 Chlorophyll A-B binding protein VirB8 PF04335.13 GAX19598.1 - 0.023 14.6 0.2 5.3 6.8 0.1 2.1 2 0 0 2 2 2 0 VirB8 protein Sorting_nexin PF03700.13 GAX19598.1 - 0.035 14.7 0.0 0.039 14.5 0.0 1.1 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain Atg14 PF10186.9 GAX19599.1 - 0.34 9.9 6.0 0.5 9.4 6.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tho2 PF11262.8 GAX19599.1 - 1.9 7.6 4.4 2.7 7.1 4.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4337 PF14235.6 GAX19599.1 - 2.5 8.2 9.6 4.2 7.5 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ank_2 PF12796.7 GAX19600.1 - 1.2e-14 54.6 2.9 0.012 16.2 0.0 6.3 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 GAX19600.1 - 2.6e-09 36.9 0.0 0.001 18.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ank PF00023.30 GAX19600.1 - 4.2e-09 36.4 15.3 0.16 12.5 0.1 8.0 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 GAX19600.1 - 1.3e-07 32.0 2.5 0.098 13.3 0.1 5.9 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX19600.1 - 1.1e-06 28.7 6.3 0.59 10.5 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19600.1 - 1.4e-05 25.1 14.8 4.3 8.2 0.0 7.5 8 0 0 8 8 8 4 Ankyrin repeat Pkinase_Tyr PF07714.17 GAX19600.1 - 6.6e-05 22.3 0.0 0.0002 20.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase ELO PF01151.18 GAX19601.1 - 3.6e-60 203.6 21.5 4.5e-60 203.3 21.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 GAX19602.1 - 1.7e-64 217.8 21.2 2e-64 217.5 21.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 GAX19603.1 - 4e-67 226.4 23.0 5e-67 226.1 23.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family XRN_N PF03159.18 GAX19604.1 - 6.6e-88 294.2 0.0 9.7e-88 293.7 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 GAX19604.1 - 2.5e-87 293.7 3.4 2.5e-87 293.7 3.4 2.9 2 1 0 2 2 2 1 Xrn1 helical domain Proteasome PF00227.26 GAX19604.1 - 4.5e-42 143.7 0.0 1.2e-41 142.3 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit GFO_IDH_MocA PF01408.22 GAX19604.1 - 1.2e-18 68.0 0.0 2.8e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold XRN1_D1 PF18332.1 GAX19604.1 - 1.1e-15 57.9 0.0 3.2e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain Pribosyltran PF00156.27 GAX19605.1 - 1.3e-14 54.0 0.0 1.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAX19605.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DHHC PF01529.20 GAX19606.1 - 8.2e-31 106.9 13.9 8.2e-31 106.9 13.9 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase TolA_bind_tri PF16331.5 GAX19607.1 - 0.013 15.6 1.5 0.013 15.6 1.5 10.2 5 3 5 10 10 10 0 TolA binding protein trimerisation TSC22 PF01166.18 GAX19607.1 - 0.021 15.1 0.0 0.021 15.1 0.0 8.2 10 3 3 13 13 13 0 TSC-22/dip/bun family KASH_CCD PF14662.6 GAX19607.1 - 0.11 12.3 87.4 0.012 15.4 17.0 5.0 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF2461 PF09365.10 GAX19607.1 - 0.22 11.4 1.2 6.3 6.7 0.1 3.0 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) UPF0242 PF06785.11 GAX19607.1 - 0.46 10.6 86.8 0.29 11.2 12.3 5.2 3 2 2 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 GAX19607.1 - 0.72 8.7 92.9 0.16 10.8 13.3 5.5 2 2 2 5 5 5 0 Spc7 kinetochore protein Fez1 PF06818.15 GAX19607.1 - 7.2 7.0 84.0 0.32 11.4 12.8 4.9 1 1 2 4 4 4 0 Fez1 DUF3287 PF11690.8 GAX19608.1 - 3.5 7.4 8.8 1.1 8.9 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) Xpo1 PF08389.12 GAX19609.1 - 5.8e-06 26.4 4.8 0.0023 18.0 0.2 3.9 3 1 1 4 4 4 2 Exportin 1-like protein HMG_box PF00505.19 GAX19610.1 - 9.1e-12 45.2 2.9 6.9e-07 29.6 0.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX19610.1 - 1.9e-06 28.4 4.5 6.7e-05 23.4 1.1 3.1 4 0 0 4 4 4 2 HMG-box domain YABBY PF04690.13 GAX19610.1 - 6.6e-05 23.5 0.2 6.6e-05 23.5 0.2 2.4 3 0 0 3 3 3 1 YABBY protein MORN PF02493.20 GAX19611.1 - 1.3e-30 103.4 36.9 1.5e-06 27.7 0.6 7.2 7 0 0 7 7 7 6 MORN repeat zf-ACC PF17848.1 GAX19611.1 - 0.51 10.5 0.0 0.51 10.5 0.0 1.9 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain AAA_25 PF13481.6 GAX19615.1 - 1.2e-20 74.0 0.0 2.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAX19615.1 - 5.1e-12 45.7 0.0 7.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 GAX19615.1 - 5e-07 30.1 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Toprim-like AAA_16 PF13191.6 GAX19615.1 - 8.7e-06 26.2 0.0 1.6e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX19615.1 - 3.9e-05 23.9 0.0 0.0001 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 GAX19615.1 - 8e-05 22.1 0.0 0.00022 20.6 0.0 1.7 1 1 0 1 1 1 1 KaiC Toprim_4 PF13662.6 GAX19615.1 - 0.00015 22.1 0.0 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 Toprim domain T2SSE PF00437.20 GAX19615.1 - 0.00036 19.7 0.0 0.00069 18.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 GAX19615.1 - 0.0067 16.2 0.1 0.019 14.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 GAX19615.1 - 0.0081 15.8 0.0 0.029 14.0 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Lar_restr_allev PF14354.6 GAX19615.1 - 0.0085 16.4 0.3 0.024 15.0 0.3 1.7 1 0 0 1 1 1 1 Restriction alleviation protein Lar NACHT PF05729.12 GAX19615.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAX19615.1 - 0.012 16.1 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 GAX19615.1 - 0.015 15.4 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 GAX19615.1 - 0.016 15.1 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 GAX19615.1 - 0.018 14.8 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX19615.1 - 0.02 15.4 1.8 0.024 15.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAX19615.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF853 PF05872.12 GAX19615.1 - 0.034 12.8 0.2 0.57 8.7 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF3854 PF12965.7 GAX19615.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Toprim_3 PF13362.6 GAX19615.1 - 0.053 13.9 0.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 Toprim domain ATP_bind_1 PF03029.17 GAX19615.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PhoH PF02562.16 GAX19615.1 - 0.094 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KIX_2 PF16987.5 GAX19615.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 KIX domain SRP54 PF00448.22 GAX19615.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain zf-CHC2 PF01807.20 GAX19615.1 - 0.17 11.7 0.1 0.52 10.1 0.1 1.8 1 0 0 1 1 1 0 CHC2 zinc finger Thioredoxin PF00085.20 GAX19616.1 - 7.3e-29 99.8 0.0 9e-29 99.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX19616.1 - 2.5e-08 34.3 0.1 3.2e-07 30.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAX19616.1 - 4.6e-07 29.7 0.0 5.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 GAX19616.1 - 4e-06 26.9 0.0 6.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX19616.1 - 5.1e-06 26.7 0.1 3.6e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 GAX19616.1 - 9.7e-06 25.1 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 GAX19616.1 - 0.00065 19.6 0.0 0.0015 18.4 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GAX19616.1 - 0.0057 16.4 0.0 0.057 13.1 0.0 1.9 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.24 GAX19616.1 - 0.008 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin HyaE PF07449.11 GAX19616.1 - 0.088 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 GAX19616.1 - 0.13 11.9 0.1 0.33 10.6 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TraF PF13728.6 GAX19616.1 - 0.22 11.3 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DOMON PF03351.17 GAX19617.1 - 1.1e-16 61.1 0.0 4.3e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 DOMON domain Cytochrom_B561 PF03188.16 GAX19617.1 - 3.1e-05 24.1 0.4 0.00011 22.3 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 GAX19617.1 - 0.0089 15.7 0.3 0.24 11.1 0.1 2.4 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 GAX19617.1 - 0.029 14.1 0.3 0.24 11.2 0.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Ank_4 PF13637.6 GAX19618.1 - 0.00034 21.1 0.4 0.018 15.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19618.1 - 0.00055 20.2 0.0 0.076 13.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 GAX19618.1 - 0.0039 17.7 0.0 0.0098 16.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX19618.1 - 0.035 14.4 0.1 2.8 8.4 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 GAX19618.1 - 0.14 12.7 0.4 0.53 10.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat DUF1336 PF07059.12 GAX19620.1 - 2.3e-50 171.8 0.0 4e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Neurexophilin PF06312.12 GAX19620.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Neurexophilin AAA PF00004.29 GAX19621.1 - 2.3e-15 57.2 0.0 5.4e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX19621.1 - 1.4e-09 38.3 0.0 5.4e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX19621.1 - 8.4e-06 26.3 0.0 2.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 GAX19621.1 - 5.3e-05 23.3 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 GAX19621.1 - 0.00015 21.7 0.0 0.00055 19.9 0.0 2.0 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 GAX19621.1 - 0.00029 20.8 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 GAX19621.1 - 0.0025 17.1 0.1 0.014 14.6 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 GAX19621.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAX19621.1 - 0.16 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.11 GAX19622.1 - 0.0029 17.7 28.9 0.0076 16.4 28.9 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 HemY_N PF07219.13 GAX19622.1 - 0.13 12.5 0.2 0.32 11.2 0.2 1.6 1 0 0 1 1 1 0 HemY protein N-terminus GAGA_bind PF06217.12 GAX19622.1 - 0.16 12.2 18.0 0.3 11.3 18.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family AP3D1 PF06375.11 GAX19622.1 - 0.26 11.5 23.8 0.74 10.0 23.8 1.8 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 MAP17 PF15807.5 GAX19622.1 - 0.92 9.8 20.9 0.78 10.0 0.1 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LapA_dom PF06305.11 GAX19622.1 - 1 9.2 0.0 1 9.2 0.0 2.4 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Coilin_N PF15862.5 GAX19622.1 - 1.1 9.1 19.6 2.2 8.1 19.6 1.6 1 0 0 1 1 1 0 Coilin N-terminus SR-25 PF10500.9 GAX19622.1 - 1.3 8.6 38.6 0.012 15.3 30.4 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4604 PF15377.6 GAX19622.1 - 3.3 8.1 29.5 7.8 6.9 29.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PTPRCAP PF15713.5 GAX19622.1 - 4.1 7.7 16.5 18 5.6 0.2 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DHHC PF01529.20 GAX19623.1 - 2.4e-27 95.7 8.6 6.6e-27 94.2 0.1 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase RRM_1 PF00076.22 GAX19624.1 - 3.5e-19 68.4 0.0 6.6e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAX19624.1 - 5.8e-05 23.1 0.2 0.00061 19.8 0.0 2.6 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 GAX19624.1 - 0.018 15.1 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 GAX19624.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF981 PF06168.11 GAX19625.1 - 0.0085 16.0 8.6 0.021 14.7 8.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF981) DUF2070 PF09843.9 GAX19625.1 - 0.68 8.1 10.2 1 7.6 10.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SBF PF01758.16 GAX19626.1 - 3e-32 111.9 18.8 6.6e-32 110.8 18.8 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 GAX19626.1 - 1.9e-14 53.7 25.4 2.7e-14 53.2 25.4 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Glycos_transf_N PF04413.16 GAX19626.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) DUF1065 PF06358.11 GAX19626.1 - 0.32 10.9 1.9 2.1 8.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1065) PhoD PF09423.10 GAX19627.1 - 1.8e-13 50.2 0.2 5.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase DUF3383 PF11863.8 GAX19627.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) RRM_1 PF00076.22 GAX19628.1 - 2.2e-17 62.6 0.0 3.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX19628.1 - 3.2e-06 26.7 0.0 6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_1 PF00685.27 GAX19629.1 - 1.9e-13 50.5 0.3 1.2e-12 47.9 0.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX19629.1 - 1.5e-08 35.3 1.0 6.9e-06 26.6 0.2 2.3 1 1 1 2 2 2 2 Sulfotransferase family Peptidase_C11 PF03415.14 GAX19630.1 - 4.2e-29 102.1 0.0 6.1e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Clostripain family Period_C PF12114.8 GAX19630.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Invasin_D3 PF09134.10 GAX19630.1 - 0.51 10.7 3.8 1.3 9.4 0.4 2.7 3 0 0 3 3 3 0 Invasin, domain 3 NmrA PF05368.13 GAX19631.1 - 2.4e-15 56.8 0.3 2.1e-14 53.7 0.3 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAX19631.1 - 5.2e-10 39.5 0.2 7.6e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding PALP PF00291.25 GAX19631.1 - 0.083 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Scramblase PF03803.15 GAX19632.1 - 6.9e-27 94.2 4.7 3.3e-13 49.5 1.5 2.1 1 1 1 2 2 2 2 Scramblase PPR_3 PF13812.6 GAX19633.1 - 1.9e-06 27.8 0.3 0.0018 18.3 0.0 4.3 3 2 2 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAX19633.1 - 4.3e-06 26.8 7.3 2.3 8.5 0.1 5.5 4 2 2 6 6 6 4 PPR repeat family PPR_1 PF12854.7 GAX19633.1 - 0.00058 19.5 5.4 1.6 8.5 0.0 5.3 4 1 0 4 4 4 1 PPR repeat PPR PF01535.20 GAX19633.1 - 0.0014 18.8 2.7 0.16 12.3 0.0 3.7 4 0 0 4 4 4 1 PPR repeat AvrPto PF11592.8 GAX19633.1 - 0.17 11.9 0.0 0.45 10.6 0.0 1.6 1 1 0 1 1 1 0 Central core of the bacterial effector protein AvrPto LRR_4 PF12799.7 GAX19634.1 - 3.3 8.3 10.6 12 6.5 0.1 5.0 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) Nuc_sug_transp PF04142.15 GAX19635.1 - 8.2e-26 90.9 8.4 1.3e-25 90.3 8.4 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAX19635.1 - 0.0011 19.2 10.2 0.0011 19.2 10.2 2.8 3 1 0 3 3 3 2 EamA-like transporter family ECF-ribofla_trS PF07155.12 GAX19635.1 - 0.97 9.4 8.2 1.1 9.2 2.3 3.1 3 0 0 3 3 3 0 ECF-type riboflavin transporter, S component 2OG-FeII_Oxy_3 PF13640.6 GAX19636.1 - 1.4e-12 48.3 0.0 2.6e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Flavi_capsid PF01003.19 GAX19636.1 - 0.084 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus capsid protein C Lactamase_B_3 PF13483.6 GAX19636.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_hydro_1 PF00232.18 GAX19637.1 - 1.6e-159 531.2 0.0 2.5e-91 306.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Lipase_GDSL_2 PF13472.6 GAX19638.1 - 2.3e-30 106.3 0.0 6.9e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX19638.1 - 3.8e-10 40.1 0.0 3.3e-05 23.9 0.0 2.9 2 2 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Attractin PF08037.11 GAX19638.1 - 0.35 10.9 1.7 0.69 10.0 0.4 2.0 2 0 0 2 2 2 0 Attractin family Lipase_GDSL_2 PF13472.6 GAX19639.1 - 6.2e-12 46.3 0.0 9.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX19639.1 - 0.0016 18.4 0.0 0.0043 17.1 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAX19640.1 - 7.7e-08 32.9 0.1 1.2e-07 32.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX19640.1 - 2e-06 27.9 0.1 4.4e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_1 PF00232.18 GAX19641.1 - 1.6e-139 465.2 0.0 6.8e-123 410.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Aa_trans PF01490.18 GAX19642.1 - 2.5e-48 164.8 9.5 3.5e-48 164.3 9.5 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAX19642.1 - 3.4e-07 29.7 8.4 3.4e-07 29.7 8.4 3.1 3 1 1 4 4 4 1 Tryptophan/tyrosine permease family Orthopox_35kD PF02250.15 GAX19642.1 - 0.045 13.4 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 35kD major secreted virus protein DUF992 PF06186.11 GAX19642.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF992) Peptidase_S9 PF00326.21 GAX19643.1 - 1.2e-19 70.6 0.0 1.3e-18 67.3 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF842 PF05811.13 GAX19644.1 - 0.1 12.3 1.3 0.69 9.6 0.3 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) CCB1 PF12046.8 GAX19645.1 - 3e-54 182.9 0.7 5.3e-54 182.1 0.2 1.6 2 0 0 2 2 2 1 Cofactor assembly of complex C subunit B DUF4131 PF13567.6 GAX19645.1 - 0.078 12.6 1.0 3.5 7.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Hist_deacetyl PF00850.19 GAX19646.1 - 3.7e-42 144.9 0.0 4.7e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Synaptobrevin PF00957.21 GAX19647.1 - 9.3e-15 54.2 1.6 1.6e-14 53.5 1.6 1.4 1 0 0 1 1 1 1 Synaptobrevin CorA PF01544.18 GAX19647.1 - 0.05 12.9 2.2 0.063 12.6 0.9 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2721 PF11026.8 GAX19647.1 - 0.55 10.1 3.3 0.61 10.0 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Spt5_N PF11942.8 GAX19647.1 - 0.55 11.2 4.0 3.1 8.8 0.6 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GGACT PF06094.12 GAX19648.1 - 1.4e-19 70.9 0.0 1.7e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Nitr_red_assoc PF09655.10 GAX19649.1 - 0.037 14.7 0.0 0.076 13.7 0.0 1.5 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Isochorismatase PF00857.20 GAX19650.1 - 2.3e-30 106.1 0.0 2.7e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Phage_holin_3_1 PF05106.12 GAX19651.1 - 0.018 15.5 2.7 0.039 14.4 0.2 2.7 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) MFS_MOT1 PF16983.5 GAX19651.1 - 1.4 9.3 16.6 1.1 9.7 4.7 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily CitMHS PF03600.16 GAX19652.1 - 2.2e-46 158.4 35.9 2.3e-36 125.5 9.9 2.3 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 GAX19652.1 - 3e-26 91.0 0.2 4.4e-09 36.1 0.0 6.1 5 1 0 5 5 5 4 TrkA-C domain ACT PF01842.25 GAX19652.1 - 0.021 14.6 0.0 0.07 12.9 0.0 1.9 1 0 0 1 1 1 0 ACT domain EbsA PF17255.2 GAX19652.1 - 3.8 7.9 6.9 0.76 10.1 3.0 1.8 2 0 0 2 2 2 0 EbsA-like protein VHL PF01847.16 GAX19653.1 - 2.1e-06 27.5 0.1 5.1e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 VHL beta domain PUB PF09409.10 GAX19653.1 - 3.8e-05 23.5 0.0 6.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 PUB domain DUF1365 PF07103.11 GAX19654.1 - 1.1e-66 224.9 5.1 1.3e-66 224.7 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Pyr_redox_2 PF07992.14 GAX19656.1 - 1.7e-44 152.3 0.0 1.3e-43 149.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX19656.1 - 5.9e-10 39.6 0.0 4.1e-06 27.3 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX19656.1 - 0.00033 20.8 0.0 0.0081 16.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX19656.1 - 0.011 14.8 0.0 0.19 10.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Mito_carr PF00153.27 GAX19657.1 - 4e-49 164.5 2.0 1.1e-15 57.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C11 PF03415.14 GAX19658.1 - 6.5e-24 85.0 0.0 8.8e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Clostripain family Period_C PF12114.8 GAX19658.1 - 0.23 11.0 0.0 0.42 10.2 0.0 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region ArsC PF03960.15 GAX19659.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 ArsC family Rhodanese_C PF12368.8 GAX19661.1 - 5.3e-14 52.3 4.1 1.5e-13 50.9 4.1 1.8 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 GAX19661.1 - 2.2e-09 37.5 0.0 5.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GAX19661.1 - 0.00022 21.7 1.7 0.00023 21.6 0.0 2.0 2 0 0 2 2 1 1 Rhodanese-like domain FYVE PF01363.21 GAX19661.1 - 0.00085 19.4 5.4 0.0027 17.8 5.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger RRM_1 PF00076.22 GAX19661.1 - 0.056 13.3 0.5 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NARP1 PF12569.8 GAX19661.1 - 0.59 9.0 18.7 0.89 8.4 18.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Bravo_FIGEY PF13882.6 GAX19661.1 - 2.9 9.3 12.5 3 9.3 9.9 2.2 2 0 0 2 2 2 0 Bravo-like intracellular region Red1 PF07964.11 GAX19661.1 - 3.4 5.8 17.2 4.7 5.3 17.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 DDRGK PF09756.9 GAX19661.1 - 4.8 6.7 22.7 0.72 9.4 16.3 2.1 2 0 0 2 2 2 0 DDRGK domain NPR3 PF03666.13 GAX19661.1 - 5.6 5.6 14.3 11 4.7 14.3 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rtf2 PF04641.12 GAX19661.1 - 6.8 6.0 21.2 20 4.5 19.3 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger AMP-binding PF00501.28 GAX19662.1 - 1.1e-62 212.0 0.0 1.7e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAX19662.1 - 1.3e-07 31.8 0.0 3.8e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAX19662.1 - 0.00011 23.1 1.0 0.003 18.5 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 GAX19662.1 - 0.0047 16.6 17.8 3.5 7.5 1.9 6.2 6 1 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAX19662.1 - 3.6 7.4 15.8 1.5 8.7 0.4 5.3 6 0 0 6 6 6 0 Hexapeptide repeat of succinyl-transferase AAA_26 PF13500.6 GAX19663.1 - 3e-39 134.9 0.0 4.5e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX19663.1 - 4e-06 26.9 0.0 9.5e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 GAX19663.1 - 0.0053 16.5 0.0 0.066 13.0 0.0 2.4 1 1 0 1 1 1 1 DRTGG domain Pkinase PF00069.25 GAX19664.1 - 7.2e-12 45.2 0.0 1.3e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19664.1 - 1.5e-10 40.8 0.0 2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 GAX19664.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase PF00069.25 GAX19665.1 - 2.1e-11 43.7 0.0 3.1e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19665.1 - 2.1e-09 37.0 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase E1-E2_ATPase PF00122.20 GAX19666.1 - 6.2e-49 166.0 2.2 6.2e-49 166.0 2.2 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX19666.1 - 1.5e-40 138.8 1.4 1.5e-40 138.8 1.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAX19666.1 - 1.7e-19 69.7 0.0 3.2e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAX19666.1 - 5e-19 69.4 1.2 1.2e-17 64.9 1.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX19666.1 - 1.1e-16 60.2 0.3 2.9e-16 58.9 0.3 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX19666.1 - 1.5e-05 24.8 0.6 6.8e-05 22.7 0.7 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX19666.1 - 0.061 13.7 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HRG PF16954.5 GAX19666.1 - 2.6 8.5 7.0 3.6 8.1 0.2 3.0 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Jag_N PF14804.6 GAX19667.1 - 0.16 12.4 0.1 0.42 11.0 0.0 1.8 2 0 0 2 2 2 0 Jag N-terminus DUF2407_C PF13373.6 GAX19668.1 - 1.8e-20 73.6 0.2 3.2e-20 72.7 0.2 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 GAX19668.1 - 4.9e-08 32.6 0.0 8.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GAX19668.1 - 2.6e-06 28.0 0.1 4.5e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX19668.1 - 0.011 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 GAX19668.1 - 0.04 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Globin PF00042.22 GAX19669.1 - 5.3e-14 52.7 0.0 8.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Globin Nudix_hydro PF18290.1 GAX19670.1 - 1.3e-21 76.4 0.3 2.7e-21 75.4 0.3 1.5 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 GAX19670.1 - 6.5e-19 68.3 0.1 1e-18 67.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain HTH_36 PF13730.6 GAX19670.1 - 0.16 12.0 0.9 0.71 9.9 0.6 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain GTP_EFTU PF00009.27 GAX19672.1 - 8.9e-32 110.2 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAX19672.1 - 4.1e-16 59.3 0.0 7.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 GAX19672.1 - 0.011 15.9 0.0 0.031 14.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 GAX19672.1 - 0.11 12.1 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PBP1_TM PF14812.6 GAX19672.1 - 1.2 9.6 6.6 2.5 8.5 6.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.11 GAX19672.1 - 3.6 6.3 5.2 5.2 5.8 5.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 tRNA_bind_3 PF17176.4 GAX19675.1 - 0.2 11.9 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA-binding domain UQ_con PF00179.26 GAX19676.1 - 1.5e-12 47.4 0.0 4.7e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX19676.1 - 0.0082 16.4 0.1 0.027 14.8 0.0 1.7 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 GAX19676.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B DsbD_2 PF13386.6 GAX19677.1 - 0.00017 21.6 5.0 0.00026 21.0 5.0 1.4 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region UPF0060 PF02694.15 GAX19678.1 - 1.4e-35 121.7 8.4 1.6e-35 121.5 8.4 1.1 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family DUF202 PF02656.15 GAX19678.1 - 0.36 11.3 6.4 34 5.0 6.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Chromate_transp PF02417.15 GAX19679.1 - 4.5e-66 221.8 32.6 2.5e-39 134.9 15.9 2.4 3 0 0 3 3 3 2 Chromate transporter 7tm_7 PF08395.12 GAX19679.1 - 0.99 8.5 2.7 1.3 8.2 0.5 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF285 PF03382.14 GAX19680.1 - 2.6e-29 101.4 3.0 5.4e-27 94.0 3.7 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 DUF285 PF03382.14 GAX19681.1 - 2.1e-38 130.8 8.9 1.5e-23 82.9 0.8 2.8 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Peptidase_M22 PF00814.25 GAX19682.1 - 1e-87 294.3 0.1 1.3e-87 293.9 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family DnaJ PF00226.31 GAX19683.1 - 8.4e-23 80.3 0.2 1.8e-22 79.2 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain SplA PF11132.8 GAX19683.1 - 0.028 14.2 0.2 0.54 10.1 0.0 2.5 2 1 0 2 2 2 0 Transcriptional regulator protein (SplA) DnaJ PF00226.31 GAX19684.1 - 3.3e-13 49.6 0.0 6.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Snf7 PF03357.21 GAX19686.1 - 3.3e-12 46.3 13.2 3.3e-12 46.3 13.2 1.8 2 0 0 2 2 2 1 Snf7 Exonuc_VII_S PF02609.16 GAX19686.1 - 0.0017 18.4 4.0 0.0075 16.3 0.2 2.7 2 0 0 2 2 2 1 Exonuclease VII small subunit DinB_2 PF12867.7 GAX19686.1 - 0.071 13.6 1.6 0.27 11.7 0.0 2.4 2 1 0 2 2 2 0 DinB superfamily MtrB PF05440.12 GAX19686.1 - 0.14 12.6 1.2 16 6.0 0.1 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF445 PF04286.12 GAX19686.1 - 0.45 10.3 6.5 0.64 9.8 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF802 PF05650.11 GAX19686.1 - 0.49 10.9 5.0 4.6 7.8 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Synaptobrevin PF00957.21 GAX19686.1 - 1.4 8.7 3.8 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Synaptobrevin CT_C_D PF02682.16 GAX19686.1 - 7.6 6.2 5.9 8.2 6.1 0.5 2.2 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D ATP-synt_C PF00137.21 GAX19687.1 - 2.3e-34 117.5 19.3 1.1e-19 70.5 6.9 2.7 2 1 0 2 2 2 2 ATP synthase subunit C TAT_signal PF10518.9 GAX19688.1 - 0.031 14.1 0.2 0.086 12.7 0.2 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 GAX19688.1 - 0.062 12.7 0.3 0.16 11.4 0.3 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PsbP PF01789.16 GAX19688.1 - 0.078 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 PsbP ATP-synt_C PF00137.21 GAX19689.1 - 8.7e-37 125.3 19.3 1.4e-23 83.0 4.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF5522 PF17653.1 GAX19689.1 - 0.095 12.7 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) MBOAT_2 PF13813.6 GAX19690.1 - 1.1e-09 38.4 0.8 1.1e-09 38.4 0.8 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RNA_pol_Rpb8 PF03870.15 GAX19691.1 - 9.8e-42 142.4 0.0 1.1e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 GAX19691.1 - 0.005 16.9 0.0 0.013 15.6 0.0 1.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase, subunit G DUF16 PF01519.16 GAX19692.1 - 0.023 15.2 4.2 0.043 14.3 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4238 PF14022.6 GAX19692.1 - 0.057 12.9 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) ADIP PF11559.8 GAX19692.1 - 0.11 12.5 7.2 0.22 11.6 7.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4763 PF15960.5 GAX19692.1 - 0.15 11.3 6.7 0.21 10.9 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) FlxA PF14282.6 GAX19692.1 - 0.53 10.3 7.4 1.1 9.3 7.4 1.5 1 0 0 1 1 1 0 FlxA-like protein SlyX PF04102.12 GAX19692.1 - 0.9 10.2 8.3 1.2 9.8 2.2 2.4 1 1 1 2 2 2 0 SlyX GrpE PF01025.19 GAX19692.1 - 1.3 8.6 4.5 3.4 7.3 4.0 1.8 2 0 0 2 2 2 0 GrpE DUF16 PF01519.16 GAX19693.1 - 1.3 9.5 6.3 1.3 9.5 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 XPG_N PF00752.17 GAX19694.1 - 2.1e-31 108.4 0.1 7.1e-31 106.7 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 GAX19694.1 - 6.7e-27 93.7 0.3 1.3e-26 92.7 0.3 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 GAX19694.1 - 6.2e-07 29.9 0.1 2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GAX19694.1 - 0.018 15.6 0.0 0.05 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Glycos_transf_3 PF00591.21 GAX19695.1 - 5.5e-28 98.2 0.0 1.1e-27 97.3 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 GAX19695.1 - 8.3e-18 64.0 0.0 2.9e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain PYNP_C PF07831.13 GAX19695.1 - 5.7e-17 61.1 0.0 1.4e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain SWIM PF04434.17 GAX19696.1 - 0.0013 18.3 1.8 0.0013 18.3 1.8 2.0 2 0 0 2 2 2 1 SWIM zinc finger zf-C3HC4_3 PF13920.6 GAX19697.1 - 5.8e-05 22.9 11.6 0.0001 22.1 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX19697.1 - 0.0018 18.6 13.0 0.0034 17.7 13.0 1.5 1 0 0 1 1 1 1 Ring finger domain UIM PF02809.20 GAX19697.1 - 0.0082 16.0 2.4 0.0082 16.0 2.4 3.7 3 0 0 3 3 3 1 Ubiquitin interaction motif zf-C3HC4_2 PF13923.6 GAX19697.1 - 0.038 13.8 12.6 0.079 12.8 12.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX19697.1 - 0.16 11.9 12.8 0.29 11.1 12.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3070 PF11270.8 GAX19697.1 - 0.6 10.4 0.0 0.6 10.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3070) DnaJ PF00226.31 GAX19698.1 - 9.4e-25 86.5 5.5 2.2e-24 85.4 5.5 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_6 PF13848.6 GAX19698.1 - 4.2e-06 26.8 0.1 4.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain zf-LITAF-like PF10601.9 GAX19699.1 - 2.5e-17 62.9 4.7 3.8e-17 62.3 4.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zinc_ribbon_4 PF13717.6 GAX19699.1 - 0.026 14.5 2.7 0.3 11.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.6 GAX19699.1 - 0.063 12.6 2.5 5 6.6 0.3 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf_C2H2_10 PF18414.1 GAX19699.1 - 0.18 11.3 3.5 0.7 9.5 0.2 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger zinc_ribbon_15 PF17032.5 GAX19699.1 - 1.7 9.4 8.7 0.31 11.8 0.8 2.2 1 1 1 2 2 2 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 GAX19699.1 - 1.9 8.5 9.2 7.6 6.6 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbons zf-LITAF-like PF10601.9 GAX19700.1 - 3e-17 62.6 5.8 4.7e-17 62.0 5.8 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.6 GAX19700.1 - 0.011 15.5 0.2 0.011 15.5 0.2 2.6 2 1 0 2 2 2 0 Cysteine-rich KTR zf-Di19 PF05605.12 GAX19700.1 - 0.019 15.3 2.0 4.7 7.6 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cortexin PF11057.8 GAX19700.1 - 0.05 13.5 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Cortexin of kidney zf-ISL3 PF14690.6 GAX19700.1 - 0.094 13.4 2.4 0.91 10.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 GAX19700.1 - 0.12 12.5 2.7 3.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 GAX19700.1 - 0.22 11.6 5.9 1.4 9.0 5.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon CpXC PF14353.6 GAX19700.1 - 0.43 10.6 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.6 GAX19700.1 - 0.59 10.1 0.2 0.59 10.1 0.2 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 GAX19700.1 - 0.65 10.0 5.3 4.4 7.3 0.0 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Rad50_zn_hook PF04423.14 GAX19700.1 - 1.3 8.9 3.4 1.6 8.7 0.3 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.12 GAX19700.1 - 2.3 8.3 6.5 14 5.7 6.5 2.0 1 1 0 1 1 1 0 zinc-ribbons DSBA PF01323.20 GAX19701.1 - 0.00014 21.7 1.4 0.0072 16.1 1.4 2.4 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 GAX19701.1 - 0.035 14.3 0.1 0.05 13.8 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin NDUF_B7 PF05676.13 GAX19701.1 - 0.49 10.2 0.0 0.49 10.2 0.0 2.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cupin_8 PF13621.6 GAX19702.1 - 1.8e-17 63.9 1.3 2.7e-17 63.3 1.3 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX19702.1 - 9e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 GAX19702.1 - 0.016 15.6 0.1 0.17 12.3 0.0 2.6 1 1 1 2 2 2 0 JmjC domain, hydroxylase STAR_dimer PF16544.5 GAX19702.1 - 0.034 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein CitMHS PF03600.16 GAX19705.1 - 6.4e-61 206.2 9.7 1.1e-47 162.7 0.0 2.1 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 GAX19705.1 - 3.3e-27 94.1 0.1 4.1e-10 39.3 0.0 6.2 5 1 1 6 6 6 5 TrkA-C domain Na_sulph_symp PF00939.19 GAX19705.1 - 1.1e-10 41.2 40.2 3.1e-07 29.8 17.3 3.1 2 1 1 3 3 3 3 Sodium:sulfate symporter transmembrane region ACT PF01842.25 GAX19705.1 - 0.0037 17.0 0.0 0.017 14.9 0.0 2.2 1 0 0 1 1 1 1 ACT domain Cupin_6 PF12852.7 GAX19705.1 - 0.026 14.3 0.3 0.094 12.4 0.2 1.9 2 0 0 2 2 2 0 Cupin DctM PF06808.12 GAX19705.1 - 0.14 10.9 31.1 0.064 12.1 16.7 2.5 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporter, DctM component CitMHS PF03600.16 GAX19706.1 - 1.2e-54 185.6 31.5 7.5e-47 160.0 4.8 2.4 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 GAX19706.1 - 1.8e-23 82.1 1.1 1.6e-09 37.5 0.0 6.0 6 1 0 6 6 6 3 TrkA-C domain ACT PF01842.25 GAX19706.1 - 0.0062 16.3 0.0 0.094 12.5 0.0 2.7 2 0 0 2 2 2 1 ACT domain Cupin_6 PF12852.7 GAX19706.1 - 0.031 14.0 0.6 0.38 10.5 0.2 2.7 3 0 0 3 3 3 0 Cupin vATP-synt_E PF01991.18 GAX19707.1 - 5.9e-48 162.9 6.7 7.3e-48 162.6 6.7 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Methyltr_RsmB-F PF01189.17 GAX19709.1 - 5.3e-21 75.2 0.0 1.3e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Sec34 PF04136.15 GAX19710.1 - 2.5e-09 37.2 3.6 4.3e-09 36.4 0.6 2.9 2 1 0 2 2 2 1 Sec34-like family TadF PF16964.5 GAX19710.1 - 0.0011 18.8 0.2 0.0011 18.8 0.2 2.0 2 0 0 2 2 2 1 Putative tight adherence pilin protein F MTHFR PF02219.17 GAX19710.1 - 0.43 9.8 10.3 0.011 15.1 3.5 1.7 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase DUF3361 PF11841.8 GAX19710.1 - 0.71 9.8 3.9 0.3 11.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Dicty_REP PF05086.12 GAX19710.1 - 5.8 4.8 8.8 9.5 4.1 8.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ALIX_LYPXL_bnd PF13949.6 GAX19711.1 - 1.8e-32 112.8 14.1 1.8e-32 112.8 14.1 3.6 4 1 0 4 4 4 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.18 GAX19711.1 - 3.7e-16 58.9 0.2 1.6e-15 56.8 0.1 2.0 2 0 0 2 2 2 1 BRO1-like domain UBA PF00627.31 GAX19711.1 - 4.4e-05 23.3 0.3 0.00013 21.8 0.3 1.9 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 GAX19711.1 - 0.0082 15.8 0.8 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 CUE domain SIR2 PF02146.17 GAX19711.1 - 0.21 11.5 0.6 16 5.3 0.1 2.7 2 0 0 2 2 2 0 Sir2 family CREPT PF16566.5 GAX19711.1 - 6 7.0 8.9 0.61 10.2 0.7 3.3 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour AKNA PF12443.8 GAX19711.1 - 7.9 7.2 7.8 12 6.7 0.7 3.9 4 0 0 4 4 4 0 AT-hook-containing transcription factor UreD PF01774.17 GAX19712.1 - 2.6e-45 154.9 0.5 5.6e-45 153.9 0.5 1.6 1 0 0 1 1 1 1 UreD urease accessory protein UreF PF01730.16 GAX19712.1 - 2.9e-14 53.8 0.2 2.9e-14 53.8 0.2 2.1 2 0 0 2 2 2 1 UreF DUF572 PF04502.13 GAX19713.1 - 0.024 14.3 0.5 0.031 13.9 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PhoU PF01895.19 GAX19713.1 - 0.055 13.9 1.2 0.43 11.1 1.2 2.1 1 1 0 1 1 1 0 PhoU domain Exonuc_VII_L PF02601.15 GAX19713.1 - 0.069 12.7 2.0 0.075 12.6 2.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Dam1 PF08653.10 GAX19713.1 - 0.074 12.9 0.3 0.22 11.4 0.3 1.9 1 0 0 1 1 1 0 DASH complex subunit Dam1 CMAS PF02353.20 GAX19714.1 - 1.1e-34 120.0 0.3 1.5e-34 119.5 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 GAX19714.1 - 1.1e-10 42.1 0.0 1.7e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX19714.1 - 1.4e-10 41.1 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX19714.1 - 8.9e-10 38.4 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX19714.1 - 9.5e-10 39.1 0.0 3.3e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX19714.1 - 4.1e-09 36.5 0.0 6.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX19714.1 - 7.6e-09 36.1 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAX19714.1 - 4.7e-05 22.9 0.1 0.0002 20.9 0.1 2.0 1 1 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 GAX19714.1 - 0.00023 21.0 0.0 0.0004 20.2 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA_U5-meth_tr PF05958.11 GAX19714.1 - 0.0019 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase FtsJ PF01728.19 GAX19714.1 - 0.0031 17.6 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase GidB PF02527.15 GAX19714.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G DOT1 PF08123.13 GAX19714.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 GAX19714.1 - 0.027 14.5 0.1 0.048 13.7 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 GAX19714.1 - 0.033 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 GAX19714.1 - 0.058 12.7 0.0 0.19 11.0 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 GAX19714.1 - 0.059 13.1 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NNMT_PNMT_TEMT PF01234.17 GAX19714.1 - 0.096 11.9 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family tRNA-synt_2c PF01411.19 GAX19716.1 - 1.2e-196 654.6 0.0 1.6e-196 654.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAX19716.1 - 2.5e-16 59.5 1.2 6.1e-16 58.2 1.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAX19716.1 - 4.3e-11 43.4 2.7 4.3e-11 43.4 2.7 2.1 2 0 0 2 2 2 1 DHHA1 domain DUF4375 PF14300.6 GAX19717.1 - 0.011 16.0 0.4 0.12 12.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) CMAS PF02353.20 GAX19718.1 - 1.2e-71 241.3 0.0 1.8e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Amino_oxidase PF01593.24 GAX19718.1 - 6.9e-16 58.6 0.0 2.8e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX19718.1 - 1.4e-15 57.2 0.1 3.7e-15 55.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_25 PF13649.6 GAX19718.1 - 2.8e-10 40.7 0.1 1.4e-09 38.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX19718.1 - 9.1e-09 35.9 0.0 2.4e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 GAX19718.1 - 3.3e-07 30.2 0.4 6.4e-07 29.3 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Methyltransf_31 PF13847.6 GAX19718.1 - 1.2e-06 28.4 0.0 4.9e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX19718.1 - 2.9e-06 27.2 0.0 7.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_9 PF13454.6 GAX19718.1 - 4.9e-05 23.4 0.4 0.00052 20.0 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAX19718.1 - 0.00021 20.6 0.1 0.00042 19.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX19718.1 - 0.0024 17.2 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAX19718.1 - 0.0044 16.2 0.1 0.0087 15.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DOT1 PF08123.13 GAX19718.1 - 0.005 16.4 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pyr_redox PF00070.27 GAX19718.1 - 0.012 16.1 0.0 0.034 14.7 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX19718.1 - 0.013 14.9 0.2 0.021 14.2 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX19718.1 - 0.014 14.1 0.1 0.022 13.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein MTS PF05175.14 GAX19718.1 - 0.014 14.9 0.0 0.038 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain MCRA PF06100.11 GAX19718.1 - 0.018 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 GAX19718.1 - 0.048 12.7 0.2 0.086 11.9 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 GAX19718.1 - 0.056 13.1 0.8 0.12 12.0 0.4 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FtsJ PF01728.19 GAX19718.1 - 0.078 13.1 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase ACP_syn_III_C PF08541.10 GAX19718.1 - 0.12 12.6 0.0 4.8 7.4 0.0 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ribosomal_L28 PF00830.19 GAX19720.1 - 0.096 12.9 0.0 0.63 10.3 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L28 family DUF21 PF01595.20 GAX19721.1 - 7.6e-22 77.8 0.2 1.7e-21 76.7 0.2 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 GAX19721.1 - 8.3e-17 61.0 0.1 4.5e-16 58.6 0.0 2.4 3 0 0 3 3 3 1 Transporter associated domain CBS PF00571.28 GAX19721.1 - 8.6e-16 58.1 3.7 1.1e-07 32.2 1.1 2.8 2 0 0 2 2 2 2 CBS domain UPF0492 PF15744.5 GAX19721.1 - 0.054 12.7 0.2 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0492 DUF4079 PF13301.6 GAX19722.1 - 1e-46 158.6 0.3 1.7e-46 157.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Lzipper-MIP1 PF14389.6 GAX19722.1 - 0.14 12.5 0.3 0.23 11.8 0.3 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Ank_2 PF12796.7 GAX19723.1 - 5.9e-08 33.2 0.0 2.8e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19723.1 - 4.6e-07 30.2 0.1 4.3e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX19723.1 - 4.3e-05 23.7 0.1 0.00067 19.9 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19723.1 - 0.0024 18.2 0.0 0.05 14.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX19723.1 - 0.0048 17.3 0.0 0.019 15.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Peptidase_M6 PF05547.11 GAX19724.1 - 0.0011 17.4 1.5 0.0024 16.3 1.5 1.5 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 Glyco_tran_WecB PF03808.13 GAX19724.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family HSP70 PF00012.20 GAX19725.1 - 8.5e-46 156.3 0.0 1.7e-42 145.5 0.0 3.4 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GAX19725.1 - 1.1e-10 40.8 0.1 2.3e-05 23.4 0.0 3.3 3 1 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GAX19725.1 - 0.039 13.7 0.1 0.095 12.4 0.1 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain AnmK PF03702.14 GAX19725.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase GRDP-like PF07173.12 GAX19726.1 - 8.5e-28 97.8 3.0 4.6e-22 79.2 0.1 3.2 3 0 0 3 3 3 3 Glycine-rich domain-containing protein-like GRDP-like PF07173.12 GAX19727.1 - 1.1e-24 87.6 6.8 4.6e-20 72.7 1.0 3.5 3 0 0 3 3 3 3 Glycine-rich domain-containing protein-like Abhydrolase_1 PF00561.20 GAX19728.1 - 4.8e-15 55.9 0.4 2.6e-14 53.5 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX19728.1 - 9.4e-11 42.7 0.5 1.3e-10 42.3 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX19728.1 - 8.6e-10 38.3 0.0 2.3e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAX19728.1 - 0.00015 22.0 0.0 0.00029 21.0 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain DUF915 PF06028.11 GAX19728.1 - 0.00035 20.0 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 GAX19728.1 - 0.00096 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein CLU_N PF15044.6 GAX19728.1 - 0.012 16.0 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term DUF3525 PF12039.8 GAX19728.1 - 0.044 12.5 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) DUF900 PF05990.12 GAX19728.1 - 0.046 13.2 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 GAX19728.1 - 0.12 12.2 0.0 1.8 8.3 0.0 2.5 2 1 1 3 3 3 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 GAX19728.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.15 GAX19728.1 - 0.25 10.5 0.0 0.34 10.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ank_5 PF13857.6 GAX19729.1 - 9.2e-09 35.4 0.1 3.4e-05 24.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX19729.1 - 3.6e-08 33.9 0.1 8.7e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19729.1 - 8.3e-07 29.4 0.0 0.00035 21.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19729.1 - 9.5e-06 25.6 0.3 0.022 15.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX19729.1 - 0.0046 17.3 0.2 9.7 6.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat AAA_12 PF13087.6 GAX19730.1 - 2.4e-54 184.0 0.0 6.2e-54 182.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX19730.1 - 1e-39 136.9 22.1 5.1e-25 88.7 0.9 4.3 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 GAX19730.1 - 9.5e-10 38.5 0.0 6.4e-09 35.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX19730.1 - 3.2e-09 37.3 0.0 6.2e-08 33.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX19730.1 - 0.0016 18.9 0.6 0.0082 16.5 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 GAX19730.1 - 0.0018 18.1 0.0 0.47 10.2 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 GAX19730.1 - 0.0041 16.4 0.0 0.0093 15.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 GAX19730.1 - 0.0071 16.3 0.0 0.02 14.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 GAX19730.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAX19730.1 - 0.015 14.9 0.0 0.045 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAX19730.1 - 0.016 14.5 0.0 0.016 14.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 GAX19730.1 - 0.019 14.8 1.4 0.99 9.2 0.0 3.0 2 0 0 2 2 2 0 Helicase PhoH PF02562.16 GAX19730.1 - 0.024 14.1 0.0 0.085 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 GAX19730.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC Ank_2 PF12796.7 GAX19732.1 - 1.1e-07 32.3 0.0 2.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX19732.1 - 1.6e-06 28.2 0.1 0.00027 21.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19732.1 - 1.2e-05 25.3 0.0 0.0095 16.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAX19732.1 - 0.00019 21.9 0.0 0.00052 20.5 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) NSP16 PF06460.12 GAX19732.1 - 0.052 12.6 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 Ank PF00023.30 GAX19732.1 - 0.13 12.8 0.0 0.56 10.7 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Astro_capsid_p PF12226.8 GAX19732.1 - 0.23 10.6 11.8 0.43 9.7 11.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Aminotran_3 PF00202.21 GAX19733.1 - 1.7e-107 359.6 0.2 2e-107 359.3 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NMDAR2_C PF10565.9 GAX19733.1 - 0.21 10.4 0.5 0.28 10.0 0.5 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Peptidase_S8 PF00082.22 GAX19736.1 - 2.1e-38 132.3 9.8 3.4e-38 131.6 9.8 1.3 1 0 0 1 1 1 1 Subtilase family Toxin_12 PF07740.12 GAX19736.1 - 0.19 12.4 10.6 0.43 11.3 10.6 1.6 1 0 0 1 1 1 0 Ion channel inhibitory toxin Mem_trans PF03547.18 GAX19737.1 - 3.7e-19 68.4 15.6 1e-10 40.6 8.2 2.1 1 1 1 2 2 2 2 Membrane transport protein zf-UBP PF02148.19 GAX19738.1 - 4.7e-18 65.3 5.2 4.7e-18 65.3 5.2 2.2 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 GAX19738.1 - 0.017 14.9 2.7 0.021 14.6 1.9 1.6 1 1 0 1 1 1 0 Variant UBP zinc finger DUF1192 PF06698.11 GAX19738.1 - 0.06 13.4 5.9 0.98 9.5 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) PEP-utilisers_N PF05524.13 GAX19738.1 - 0.1 12.8 9.9 0.15 12.2 9.5 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Connexin40_C PF16791.5 GAX19738.1 - 0.2 13.0 4.2 0.2 12.9 0.4 2.5 2 0 0 2 2 2 0 Connexin 40 C-terminal domain Fungal_TACC PF12709.7 GAX19738.1 - 4.7 7.7 9.5 0.24 11.9 1.3 2.9 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Iron_permease PF04120.12 GAX19738.1 - 9.4 6.0 7.5 0.81 9.5 1.5 2.3 2 1 1 3 3 3 0 Low affinity iron permease DAO PF01266.24 GAX19739.1 - 3.6e-51 174.8 0.5 4.3e-51 174.6 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX19739.1 - 3.3e-07 30.4 0.1 8.6e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX19739.1 - 4e-06 26.3 0.3 2.1e-05 23.9 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX19739.1 - 7.9e-06 26.4 0.3 2e-05 25.1 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX19739.1 - 6.3e-05 21.9 1.7 0.00099 17.9 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GAX19739.1 - 0.00014 21.2 0.2 0.00027 20.3 0.2 1.4 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 GAX19739.1 - 0.00015 22.0 0.1 0.00028 21.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 GAX19739.1 - 0.00022 20.6 0.1 0.00039 19.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX19739.1 - 0.00049 19.3 3.2 0.00086 18.5 3.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAX19739.1 - 0.00059 19.2 0.4 0.00086 18.6 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 GAX19739.1 - 0.00065 19.4 0.2 0.0011 18.7 0.2 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 GAX19739.1 - 0.00087 18.7 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAX19739.1 - 0.00088 18.6 0.1 0.0012 18.2 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 GAX19739.1 - 0.00098 18.3 0.7 0.028 13.5 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 GAX19739.1 - 0.0013 18.7 0.1 0.0025 17.7 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAX19739.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX19739.1 - 0.0075 15.6 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX19739.1 - 0.011 15.8 0.3 0.021 14.9 0.3 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GAX19739.1 - 0.017 15.7 0.5 0.033 14.8 0.5 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 GAX19739.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.25 GAX19739.1 - 0.032 13.7 0.9 0.049 13.1 0.2 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX19739.1 - 0.035 14.4 0.5 0.08 13.2 0.4 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 GAX19739.1 - 0.058 13.4 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 GAX19739.1 - 0.075 13.5 0.0 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 GAX19739.1 - 0.086 13.0 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDI PF00996.18 GAX19739.1 - 0.15 10.5 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Mqo PF06039.15 GAX19739.1 - 0.17 10.4 0.1 0.36 9.3 0.1 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 GAX19739.1 - 0.23 10.5 0.5 0.32 10.0 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HA PF03457.14 GAX19740.1 - 8.3e-34 115.7 9.4 4.4e-11 43.0 0.4 4.1 3 1 0 3 3 3 3 Helicase associated domain SPC25 PF06703.11 GAX19742.1 - 4.9e-34 117.5 0.0 6.6e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) STIL_N PF15253.6 GAX19742.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus UBM PF14377.6 GAX19743.1 - 0.02 14.4 0.1 0.054 13.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin binding region Stn1 PF10451.9 GAX19743.1 - 0.021 13.8 0.4 0.037 13.0 0.4 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Thioredoxin_16 PF18569.1 GAX19743.1 - 0.048 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Fea1 PF07692.11 GAX19744.1 - 1.5e-06 27.5 0.3 0.035 13.1 0.1 2.6 2 1 1 3 3 3 2 Low iron-inducible periplasmic protein Ank_2 PF12796.7 GAX19746.1 - 5.2e-10 39.8 0.4 2.8e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX19746.1 - 3e-07 30.9 0.4 0.0056 17.2 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX19746.1 - 7.9e-06 26.1 0.8 0.011 16.0 0.1 3.4 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX19746.1 - 9.8e-06 25.6 0.1 1.6 9.6 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAX19746.1 - 0.002 18.5 0.1 0.75 10.4 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Zn_Tnp_IS1595 PF12760.7 GAX19746.1 - 0.0086 16.0 1.6 0.028 14.4 1.6 1.9 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF551 PF04448.12 GAX19746.1 - 0.017 16.0 0.3 0.67 10.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF551) A2L_zn_ribbon PF08792.10 GAX19746.1 - 0.13 12.0 2.6 0.39 10.5 2.6 1.8 1 0 0 1 1 1 0 A2L zinc ribbon domain GATase_2 PF00310.21 GAX19747.1 - 4.6e-167 556.0 0.0 6.6e-167 555.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GAX19747.1 - 9.1e-156 518.6 0.7 2.6e-152 507.2 0.1 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GAX19747.1 - 6.7e-110 367.0 0.0 2.1e-108 362.1 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GAX19747.1 - 2.6e-81 271.8 3.2 4.5e-81 271.0 3.2 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 GAX19747.1 - 1.7 7.6 5.9 0.84 8.6 1.3 2.4 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Aldedh PF00171.22 GAX19748.1 - 8.7e-76 255.3 0.0 1.1e-75 255.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family XPC-binding PF09280.11 GAX19748.1 - 0.18 11.5 2.1 3 7.7 0.0 3.3 3 0 0 3 3 3 0 XPC-binding domain TBCC PF07986.12 GAX19749.1 - 2.1e-27 95.2 0.7 4.3e-27 94.2 0.7 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 GAX19749.1 - 1.2e-06 28.2 0.2 2.3e-06 27.3 0.2 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal AA_permease_2 PF13520.6 GAX19750.1 - 5.9e-38 130.8 40.3 5.9e-38 130.8 40.3 1.9 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAX19750.1 - 1.3e-18 66.8 36.6 2.3e-18 66.1 36.6 1.4 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GAX19750.1 - 1.2e-12 47.7 5.1 1.2e-12 47.7 5.1 3.3 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.13 GAX19750.1 - 0.00017 20.5 17.3 0.0012 17.8 10.0 3.1 2 1 0 2 2 2 1 Spore germination protein TMEM208_SND2 PF05620.11 GAX19750.1 - 5.2 6.8 6.0 18 5.1 1.7 2.6 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 ENT PF03735.14 GAX19751.1 - 0.037 14.1 0.1 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 ENT domain Bcl-2 PF00452.19 GAX19751.1 - 0.15 12.8 0.1 0.25 12.1 0.1 1.4 1 1 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family 2_5_RNA_ligase2 PF13563.6 GAX19752.1 - 0.08 12.8 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily DDRGK PF09756.9 GAX19753.1 - 3.5e-10 39.8 33.6 9.1e-09 35.2 33.6 2.2 1 1 0 1 1 1 1 DDRGK domain Neur_chan_memb PF02932.16 GAX19753.1 - 0.14 12.2 4.7 0.21 11.6 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 GAX19753.1 - 0.21 10.3 6.5 0.25 10.0 6.5 1.3 1 0 0 1 1 1 0 Presenilin DUF2868 PF11067.8 GAX19753.1 - 0.6 9.6 9.0 0.86 9.0 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) FAM60A PF15396.6 GAX19753.1 - 0.69 9.9 5.1 0.85 9.6 5.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 GAX19753.1 - 4.7 5.2 7.9 5.1 5.1 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2229 PF09989.9 GAX19753.1 - 5.5 6.6 8.9 32 4.1 8.9 2.0 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) MFS_1 PF07690.16 GAX19754.1 - 6.6e-21 74.6 23.3 6.6e-21 74.6 23.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 GAX19754.1 - 0.0072 15.6 1.8 0.0072 15.6 1.8 2.8 2 1 0 2 2 2 1 Sporulation factor SpoIIGA Spc7 PF08317.11 GAX19755.1 - 1 8.2 30.3 4.1 6.2 30.3 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 GAX19755.1 - 8.6 6.4 35.3 6.5 6.8 7.9 3.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nup192 PF11894.8 GAX19756.1 - 2.8e-32 111.0 11.4 7.1e-21 73.2 0.1 4.1 4 0 0 4 4 4 4 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nucleoporin_FG2 PF15967.5 GAX19756.1 - 1.4 7.4 13.1 3 6.3 13.1 1.5 1 0 0 1 1 1 0 Nucleoporin FG repeated region Glyco_transf_90 PF05686.12 GAX19757.1 - 5.7e-18 65.0 2.3 5.9e-16 58.4 0.9 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAX19757.1 - 0.006 16.9 0.8 0.052 13.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 MobA_MobL PF03389.15 GAX19757.1 - 0.078 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 MobA/MobL family Atx10homo_assoc PF09759.9 GAX19758.1 - 0.00019 21.4 0.7 0.01 15.9 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain SGTA_dimer PF16546.5 GAX19758.1 - 0.068 13.0 0.2 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Homodimerisation domain of SGTA McrBC PF10117.9 GAX19758.1 - 0.078 12.1 0.7 0.12 11.5 0.7 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component DFP PF04127.15 GAX19759.1 - 1e-15 58.0 0.0 4.2e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein ABC_tran PF00005.27 GAX19760.1 - 6.4e-48 162.7 0.0 1.5e-22 80.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX19760.1 - 6.8e-18 64.5 1.7 6.8e-18 64.5 1.7 4.5 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 GAX19760.1 - 4.6e-17 62.8 5.1 0.00045 20.1 0.1 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX19760.1 - 8.5e-11 41.7 5.8 0.021 14.2 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX19760.1 - 1.4e-08 34.3 0.0 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAX19760.1 - 2.8e-07 31.0 0.0 0.021 15.2 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GAX19760.1 - 2.8e-07 31.3 21.4 0.0024 18.4 0.1 5.3 4 1 0 5 5 4 2 AAA domain AAA_28 PF13521.6 GAX19760.1 - 1.6e-05 25.2 0.1 0.043 14.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX19760.1 - 3.1e-05 24.3 0.2 0.37 11.1 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX19760.1 - 4.1e-05 24.1 0.6 0.062 13.9 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.6 GAX19760.1 - 4.3e-05 24.0 0.4 0.063 13.6 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 GAX19760.1 - 7.9e-05 22.7 0.1 0.13 12.3 0.0 3.4 4 0 0 4 4 2 1 AAA domain MMR_HSR1 PF01926.23 GAX19760.1 - 0.0001 22.4 0.0 0.18 11.9 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 GAX19760.1 - 0.00012 22.2 0.1 0.39 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAX19760.1 - 0.00014 21.8 0.1 0.47 10.4 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 GAX19760.1 - 0.00014 21.4 0.0 0.51 9.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 GAX19760.1 - 0.00018 21.3 0.0 0.78 9.4 0.1 3.1 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 GAX19760.1 - 0.00022 21.6 0.1 0.6 10.5 0.0 2.9 3 0 0 3 3 2 1 RNA helicase NB-ARC PF00931.22 GAX19760.1 - 0.0003 20.1 0.0 0.34 10.0 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain AAA_15 PF13175.6 GAX19760.1 - 0.0004 20.2 10.6 0.024 14.3 2.6 3.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_30 PF13604.6 GAX19760.1 - 0.00091 19.0 0.0 1.8 8.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.17 GAX19760.1 - 0.0011 18.8 0.0 0.14 11.9 0.0 2.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_27 PF13514.6 GAX19760.1 - 0.0014 18.2 0.8 0.96 9.0 0.0 3.3 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAX19760.1 - 0.0017 18.3 0.8 0.11 12.3 0.0 2.8 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAX19760.1 - 0.0018 18.3 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 GAX19760.1 - 0.0046 16.9 0.1 2 8.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 GAX19760.1 - 0.0051 16.6 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein TsaE PF02367.17 GAX19760.1 - 0.0061 16.6 0.0 0.38 10.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 GAX19760.1 - 0.0098 15.6 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase PduV-EutP PF10662.9 GAX19760.1 - 0.024 14.4 0.0 2 8.1 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MukB PF04310.12 GAX19760.1 - 0.029 14.2 0.4 5.3 6.8 0.0 2.9 3 0 0 3 3 2 0 MukB N-terminal Rad17 PF03215.15 GAX19760.1 - 0.031 14.2 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Roc PF08477.13 GAX19760.1 - 0.041 14.1 0.0 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAX19760.1 - 0.056 12.9 0.4 0.32 10.4 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAX19760.1 - 0.06 12.5 0.1 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 GAX19760.1 - 0.069 12.5 0.0 6.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 GAX19760.1 - 0.085 12.4 0.1 4.6 6.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 GAX19760.1 - 0.092 12.3 0.0 11 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAX19760.1 - 0.1 12.5 0.9 5.5 6.9 0.2 2.8 2 1 0 2 2 2 0 NTPase RuvB_N PF05496.12 GAX19760.1 - 0.15 11.8 0.2 2.1 8.1 0.0 2.6 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF5446 PF17522.2 GAX19760.1 - 0.16 12.1 5.3 0.6 10.3 2.7 3.0 3 0 0 3 3 2 0 Family of unknown function (DUF5446) SRP54 PF00448.22 GAX19760.1 - 0.22 11.1 3.2 2.4 7.8 0.3 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 GAX19760.1 - 0.25 11.6 3.3 3.5 7.9 0.0 3.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit CENP-N PF05238.13 GAX19760.1 - 0.37 10.0 2.6 0.66 9.2 2.6 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF87 PF01935.17 GAX19760.1 - 0.96 9.5 4.9 37 4.3 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_17 PF13207.6 GAX19760.1 - 3.2 8.2 8.8 2.8 8.4 0.1 3.8 3 1 0 3 3 3 0 AAA domain PRK PF00485.18 GAX19761.1 - 8.1e-10 38.8 0.0 2.3e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAX19761.1 - 1.3e-08 35.5 0.0 3.3e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 GAX19761.1 - 7e-06 26.0 0.0 0.0051 16.7 0.0 2.4 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_17 PF13207.6 GAX19761.1 - 9.2e-05 22.9 0.4 0.029 14.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain Thymidylate_kin PF02223.17 GAX19761.1 - 0.00018 21.3 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase SKI PF01202.22 GAX19761.1 - 0.00087 19.4 0.0 0.57 10.3 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.6 GAX19761.1 - 0.0013 18.9 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX19761.1 - 0.0083 16.5 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 GAX19761.1 - 0.0088 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 GAX19761.1 - 0.017 14.7 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MeaB PF03308.16 GAX19761.1 - 0.023 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 GAX19761.1 - 0.059 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX19761.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 GAX19761.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ADK PF00406.22 GAX19761.1 - 0.15 12.2 0.3 2.1 8.4 0.1 2.6 2 1 1 3 3 3 0 Adenylate kinase AAA_30 PF13604.6 GAX19761.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain dCMP_cyt_deam_1 PF00383.23 GAX19762.1 - 1.7e-47 159.5 0.2 1.1e-26 92.7 0.2 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX19762.1 - 5.9e-23 81.1 0.1 5.7e-13 48.8 0.1 2.3 2 0 0 2 2 2 2 MafB19-like deaminase APOBEC4_like PF18774.1 GAX19762.1 - 6.3e-06 26.1 0.1 0.0026 17.7 0.1 2.3 2 0 0 2 2 2 2 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 GAX19762.1 - 0.00083 19.5 1.1 0.25 11.5 0.3 2.5 2 0 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 GAX19762.1 - 0.00085 19.4 0.6 1.1 9.4 0.1 2.6 2 0 0 2 2 2 2 Bd3614-like deaminase NAD1 PF18778.1 GAX19762.1 - 0.0015 18.7 1.0 0.5 10.4 0.5 2.5 2 0 0 2 2 2 2 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 GAX19762.1 - 0.005 16.7 0.9 1.2 9.1 0.2 2.5 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC2 PF18772.1 GAX19762.1 - 0.0059 16.7 0.8 1.1 9.3 0.3 2.4 2 0 0 2 2 2 2 APOBEC2 APOBEC3 PF18771.1 GAX19762.1 - 0.035 14.2 0.3 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 APOBEC3 APOBEC4 PF18775.1 GAX19762.1 - 0.29 11.3 1.2 33 4.7 0.3 2.7 2 1 0 2 2 2 0 APOBEC4 TAXi_N PF14543.6 GAX19764.1 - 6.7e-18 65.5 0.2 1.1e-17 64.8 0.2 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX19764.1 - 1.3e-12 47.8 0.0 2.1e-05 24.1 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX19764.1 - 0.026 14.3 0.0 12 5.7 0.0 2.8 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAX19764.1 - 0.13 12.9 0.1 15 6.3 0.0 3.1 4 0 0 4 4 4 0 Aspartyl protease DUF676 PF05057.14 GAX19765.1 - 0.00029 20.4 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 GAX19765.1 - 0.00042 19.9 0.0 0.00065 19.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 GAX19765.1 - 0.00073 19.2 0.8 0.023 14.3 0.8 2.1 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Cutinase PF01083.22 GAX19765.1 - 0.0014 18.6 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 GAX19765.1 - 0.0058 16.5 0.1 0.027 14.3 0.0 2.1 2 1 1 3 3 3 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAX19765.1 - 0.0068 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX19765.1 - 0.0084 16.7 0.0 0.016 15.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAX19765.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 GAX19765.1 - 0.012 15.5 0.1 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_8 PF06259.12 GAX19765.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF1749 PF08538.10 GAX19765.1 - 0.023 13.8 0.0 0.055 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Palm_thioest PF02089.15 GAX19765.1 - 0.033 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase FSH1 PF03959.13 GAX19765.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Chitin_synth_2 PF03142.15 GAX19765.1 - 0.13 10.9 0.7 0.17 10.4 0.7 1.1 1 0 0 1 1 1 0 Chitin synthase Abhydrolase_1 PF00561.20 GAX19765.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M43 PF05572.13 GAX19766.1 - 2.6e-16 59.9 0.0 7.2e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX19766.1 - 0.02 15.1 0.5 0.064 13.4 0.6 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 GAX19766.1 - 0.32 11.1 2.2 0.65 10.1 0.2 2.3 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Pkinase PF00069.25 GAX19767.1 - 7e-71 238.7 0.0 8.5e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19767.1 - 1.4e-33 116.3 0.0 1.7e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX19767.1 - 3.4e-06 27.2 0.2 4.9e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX19767.1 - 0.00016 21.1 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAX19767.1 - 0.00016 20.6 0.0 0.00023 20.1 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX19767.1 - 0.0047 16.3 0.3 0.0063 15.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAX19767.1 - 0.07 12.1 0.1 2.1 7.2 0.0 2.0 1 1 1 2 2 2 0 Haspin like kinase domain CCM2_C PF16545.5 GAX19767.1 - 0.16 12.5 0.2 15 6.2 0.1 2.4 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Filament PF00038.21 GAX19768.1 - 0.0057 16.3 14.8 0.0057 16.3 14.8 2.1 1 1 1 2 2 2 1 Intermediate filament protein ERM PF00769.19 GAX19768.1 - 0.75 9.6 49.5 0.3 10.9 19.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Bacillus_HBL PF05791.11 GAX19768.1 - 3.4 7.5 17.8 0.3 10.9 2.3 3.2 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 GAX19768.1 - 5.3 7.1 20.8 3.2 7.8 6.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 GAX19768.1 - 7.5 5.9 35.6 0.15 11.5 15.6 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal LSM PF01423.22 GAX19769.1 - 2.2e-10 40.1 0.2 7.7e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 LSM domain Pep_M12B_propep PF01562.19 GAX19769.1 - 0.0059 16.8 0.1 1.5 9.0 0.0 2.8 2 1 0 2 2 2 2 Reprolysin family propeptide SpoU_methylase PF00588.19 GAX19770.1 - 2e-23 83.1 0.0 4.6e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF3524 PF12038.8 GAX19770.1 - 1e-19 71.0 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 GAX19770.1 - 2.1e-13 50.2 0.0 3.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 RVT_2 PF07727.14 GAX19772.1 - 9.4e-16 58.2 0.2 3.9e-15 56.2 0.2 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCMA-Tall_bind PF09257.10 GAX19773.1 - 0.18 12.0 0.2 0.33 11.1 0.2 1.4 1 0 0 1 1 1 0 BCMA, TALL-1 binding Ank_2 PF12796.7 GAX19774.1 - 4.6e-32 110.5 0.0 3.2e-12 46.9 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 GAX19774.1 - 6.1e-23 81.4 6.5 6.1e-23 81.4 6.5 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 GAX19774.1 - 5.3e-22 77.9 5.2 3e-07 30.9 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX19774.1 - 1.1e-14 54.2 0.1 0.00021 21.5 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX19774.1 - 2.4e-14 53.0 2.1 0.0046 17.3 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 GAX19774.1 - 1.3e-13 49.7 0.1 0.071 13.7 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat LPMO_10 PF03067.15 GAX19775.1 - 1.2e-27 97.8 0.2 1.2e-27 97.8 0.2 1.6 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 GAX19776.1 - 2.2e-08 35.0 0.4 2.7e-08 34.7 0.4 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Cadherin_C PF01049.17 GAX19777.1 - 0.42 10.9 5.9 0.1 13.0 1.4 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic region Cupin_1 PF00190.22 GAX19778.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Cupin IQ PF00612.27 GAX19780.1 - 4.1e-59 190.8 154.2 0.0023 17.6 0.1 28.8 29 0 0 29 29 29 27 IQ calmodulin-binding motif ATP-synt_Z PF16594.5 GAX19782.1 - 5.1 6.7 7.7 0.17 11.4 0.6 2.2 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated Choline_transpo PF04515.12 GAX19783.1 - 1.4e-56 192.1 19.6 1.4e-56 192.1 19.6 2.1 1 1 0 2 2 2 1 Plasma-membrane choline transporter PAP2 PF01569.21 GAX19784.1 - 2e-07 30.8 0.2 7.3e-07 29.0 0.2 1.9 1 1 0 1 1 1 1 PAP2 superfamily CLP_protease PF00574.23 GAX19785.1 - 5.2e-79 264.4 0.0 6.2e-79 264.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease Chisel PF15355.6 GAX19785.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel W2 PF02020.18 GAX19786.1 - 3.9e-12 46.1 3.1 8.3e-12 45.1 3.1 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Ntox1 PF15500.6 GAX19786.1 - 0.15 12.4 3.5 4.3 7.7 0.2 2.9 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 BTP PF05232.12 GAX19787.1 - 0.091 12.8 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Chlorhexidine efflux transporter Glyoxalase_4 PF13669.6 GAX19789.1 - 0.0017 18.6 0.0 1.2 9.5 0.1 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FSIP2 PF15783.5 GAX19789.1 - 0.031 12.3 0.1 0.047 11.6 0.1 1.2 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 PMEI PF04043.15 GAX19789.1 - 0.41 11.0 5.5 1.3 9.4 0.4 3.1 2 1 1 3 3 3 0 Plant invertase/pectin methylesterase inhibitor zf-RING_2 PF13639.6 GAX19790.1 - 7.3e-11 42.2 14.4 2.7e-10 40.4 14.4 2.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX19790.1 - 3.5e-07 30.4 8.7 1e-06 28.9 8.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAX19790.1 - 1.6e-06 27.8 11.0 1.6e-06 27.8 11.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX19790.1 - 6.3e-06 25.9 12.8 6.3e-06 25.9 12.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX19790.1 - 6.1e-05 23.0 4.6 6.1e-05 23.0 4.6 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX19790.1 - 0.0001 22.1 12.6 0.00023 21.0 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX19790.1 - 0.00052 19.9 12.8 0.0011 18.9 12.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAX19790.1 - 0.00075 19.1 9.1 0.0018 17.8 9.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 GAX19790.1 - 0.0017 18.2 14.5 0.0021 17.9 12.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX19790.1 - 0.0071 16.4 4.8 0.017 15.1 4.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAX19790.1 - 0.017 15.0 11.2 0.047 13.6 11.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF998 PF06197.13 GAX19790.1 - 0.33 10.5 0.1 0.33 10.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF998) Prok-RING_1 PF14446.6 GAX19790.1 - 0.62 10.0 12.0 0.76 9.8 9.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 GAX19790.1 - 0.62 9.9 5.6 1.7 8.5 5.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 GAX19790.1 - 1.7 8.9 10.9 8.5 6.6 10.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Metallophos PF00149.28 GAX19791.1 - 8e-32 111.4 0.0 2.1e-31 110.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAX19791.1 - 2.9e-15 56.4 0.2 5.1e-15 55.6 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Aminotran_4 PF01063.19 GAX19792.1 - 4.9e-43 147.6 0.1 7e-43 147.1 0.1 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Sulfotransfer_3 PF13469.6 GAX19792.1 - 0.006 17.0 0.0 0.029 14.7 0.0 2.2 3 1 0 3 3 3 1 Sulfotransferase family Glyco_hydro_10 PF00331.20 GAX19793.1 - 9.7e-80 268.1 0.0 1.1e-79 267.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4252 PF14060.6 GAX19794.1 - 0.022 14.7 0.2 0.028 14.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) ATP-synt_B PF00430.18 GAX19794.1 - 0.39 10.8 7.4 0.6 10.2 6.8 1.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Leo1 PF04004.13 GAX19795.1 - 3e-35 121.5 0.1 3e-35 121.5 0.1 2.9 3 0 0 3 3 3 1 Leo1-like protein PCMT PF01135.19 GAX19796.1 - 1.6e-24 86.9 0.0 2.3e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_3_Rpc31 PF11705.8 GAX19796.1 - 0.021 15.1 8.6 0.033 14.5 8.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 KBP_C PF12309.8 GAX19796.1 - 0.04 13.4 4.4 0.056 13.0 4.4 1.2 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Fibrillarin PF01269.17 GAX19796.1 - 0.054 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Ubie_methyltran PF01209.18 GAX19796.1 - 0.094 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAX19796.1 - 0.11 13.2 0.0 0.38 11.5 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 GAX19796.1 - 0.23 11.0 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 GAX19796.1 - 0.24 12.1 0.6 0.96 10.1 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 GAX19796.1 - 0.24 11.4 0.8 0.84 9.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain FH2 PF02181.23 GAX19796.1 - 0.36 9.9 4.6 0.54 9.3 4.6 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Cwf_Cwc_15 PF04889.12 GAX19796.1 - 0.39 10.4 17.7 0.67 9.6 17.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAX19796.1 - 2.3 7.5 12.4 3.4 6.9 12.4 1.1 1 0 0 1 1 1 0 NOA36 protein V_ATPase_I PF01496.19 GAX19796.1 - 2.8 5.7 5.0 4.1 5.2 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRN3 PF05327.11 GAX19796.1 - 3.7 6.0 11.1 5.3 5.5 11.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GAX19796.1 - 9.2 4.2 17.3 15 3.6 17.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GAX19796.1 - 9.6 5.3 8.9 16 4.6 8.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit LRR_6 PF13516.6 GAX19797.1 - 0.062 13.4 20.3 0.21 11.7 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat RolB_RolC PF02027.17 GAX19797.1 - 0.081 12.6 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 RolB/RolC glucosidase family DUF3336 PF11815.8 GAX19798.1 - 4.7e-23 81.4 0.0 1.4e-22 79.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAX19798.1 - 8.4e-16 58.8 0.0 2.9e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Peptidase_M41 PF01434.18 GAX19799.1 - 1.6e-61 207.5 1.3 3.3e-61 206.5 1.3 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAX19799.1 - 1.6e-40 138.6 0.0 5.9e-40 136.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX19799.1 - 4.3e-07 29.6 0.0 9.4e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAX19799.1 - 4.4e-05 23.3 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX19799.1 - 4.4e-05 23.9 2.1 0.00057 20.3 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 GAX19799.1 - 8.9e-05 21.8 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 GAX19799.1 - 0.00024 21.1 0.1 0.0013 18.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX19799.1 - 0.0019 18.4 4.5 0.1 12.9 0.1 3.4 2 2 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAX19799.1 - 0.0021 18.6 0.0 0.024 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAX19799.1 - 0.003 17.3 0.0 0.0089 15.8 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 GAX19799.1 - 0.0038 17.2 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 GAX19799.1 - 0.015 15.5 0.0 0.047 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAX19799.1 - 0.015 14.7 0.2 0.037 13.4 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 GAX19799.1 - 0.018 15.5 0.0 0.053 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAX19799.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAX19799.1 - 0.035 14.3 0.8 0.21 11.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 GAX19799.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 GAX19799.1 - 0.057 13.1 0.2 0.34 10.6 0.0 2.5 3 1 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 GAX19799.1 - 0.065 12.6 0.3 0.23 10.8 0.1 2.0 2 0 0 2 2 2 0 KaiC IclR PF01614.18 GAX19799.1 - 0.092 12.6 0.2 0.32 10.8 0.1 1.9 1 1 0 1 1 1 0 Bacterial transcriptional regulator dsDNA_bind PF01984.20 GAX19799.1 - 0.096 13.0 5.1 0.33 11.2 5.1 1.9 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Peptidase_M50B PF13398.6 GAX19799.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Parvo_NS1 PF01057.17 GAX19799.1 - 0.32 10.0 0.0 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 GAX19799.1 - 0.45 10.4 3.8 0.45 10.4 0.0 2.7 3 0 0 3 3 3 0 NACHT domain SIP1 PF04938.12 GAX19799.1 - 1.4 8.6 8.4 2.5 7.7 8.4 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) AAA_25 PF13481.6 GAX19799.1 - 1.8 8.1 4.8 1 8.9 0.5 2.6 2 1 1 3 3 2 0 AAA domain FKBP_C PF00254.28 GAX19800.1 - 4.7e-27 94.1 0.0 6e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 GAX19801.1 - 1.1e-32 112.2 0.0 1.2e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sedlin_N PF04628.13 GAX19802.1 - 3.1e-36 124.4 0.8 3.5e-36 124.2 0.8 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAX19802.1 - 9.5e-09 35.3 0.3 1.3e-08 34.9 0.3 1.3 1 1 0 1 1 1 1 Sybindin-like family DUF1697 PF08002.11 GAX19802.1 - 0.085 13.3 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) ATP-synt_F PF01990.17 GAX19804.1 - 1.4e-33 115.1 0.1 1.6e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Pox_A_type_inc PF04508.12 GAX19806.1 - 0.29 11.0 0.0 0.29 11.0 0.0 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Tropomyosin_1 PF12718.7 GAX19807.1 - 0.011 15.9 9.2 0.016 15.4 9.2 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF4660 PF15559.6 GAX19807.1 - 0.046 14.0 1.5 0.11 12.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) RRF_GI PF12614.8 GAX19807.1 - 0.06 13.5 1.0 0.086 13.0 1.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Q_salvage PF10343.9 GAX19808.1 - 2.7e-62 210.9 0.2 3.9e-62 210.4 0.2 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 GAX19808.1 - 0.00012 21.0 0.1 0.0018 17.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1688) EnY2 PF10163.9 GAX19808.1 - 0.035 14.5 0.4 0.11 12.9 0.1 1.9 2 0 0 2 2 2 0 Transcription factor e(y)2 PNTB PF02233.16 GAX19811.1 - 8.5e-167 555.7 22.8 8.5e-167 555.7 22.8 2.9 3 0 0 3 3 3 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAX19811.1 - 2.5e-59 200.2 0.2 5.9e-59 199.0 0.2 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAX19811.1 - 2.2e-34 118.7 0.2 6.4e-34 117.2 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAX19811.1 - 3.8e-26 91.3 3.5 3.8e-26 91.3 3.5 4.2 2 1 1 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch ADH_zinc_N PF00107.26 GAX19811.1 - 0.00034 20.6 0.3 0.013 15.5 0.1 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.22 GAX19811.1 - 0.0015 18.3 0.8 0.22 11.3 0.2 3.5 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 GAX19811.1 - 0.0016 17.8 0.0 0.22 10.9 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 GAX19811.1 - 0.019 15.2 0.5 0.019 15.2 0.5 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX19811.1 - 0.035 13.4 0.1 0.078 12.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase POR_N PF01855.19 GAX19812.1 - 3.6e-70 236.3 0.2 5.5e-70 235.7 0.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.20 GAX19812.1 - 2.4e-24 86.2 0.0 6.3e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX19812.1 - 8.8e-23 81.1 0.0 1.9e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR PF01558.18 GAX19812.1 - 5.2e-16 59.2 0.0 9.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 GAX19812.1 - 8.3e-11 42.5 0.0 6.7e-10 39.6 0.0 2.6 3 0 0 3 3 1 1 Oxidoreductase NAD-binding domain EKR PF10371.9 GAX19812.1 - 1.5e-09 37.5 0.0 6e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function Fer4_16 PF13484.6 GAX19812.1 - 5.7e-08 33.6 7.5 1.8e-07 32.0 7.5 2.0 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 GAX19812.1 - 8.5e-08 32.7 8.2 2.8e-07 31.0 8.2 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 GAX19812.1 - 4e-07 29.6 21.0 8.5e-05 22.2 2.4 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 GAX19812.1 - 4.8e-07 29.8 8.8 8e-07 29.1 7.2 2.3 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAX19812.1 - 4e-06 26.7 23.7 1.3e-05 25.0 3.9 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain PFOR_II PF17147.4 GAX19812.1 - 8.4e-06 26.0 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_10 PF13237.6 GAX19812.1 - 1.2e-05 25.4 11.8 1.5e-05 25.0 10.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 GAX19812.1 - 1.9e-05 24.5 0.1 6e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_8 PF13183.6 GAX19812.1 - 3.7e-05 24.1 5.5 0.00012 22.5 5.5 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 GAX19812.1 - 0.00016 21.7 12.1 0.0038 17.3 12.0 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 GAX19812.1 - 0.00024 21.6 8.2 0.0014 19.1 8.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAX19812.1 - 0.0024 17.9 22.2 0.016 15.3 2.8 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 GAX19812.1 - 0.012 16.5 19.1 0.04 14.9 5.3 3.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 GAX19812.1 - 0.021 15.3 15.5 0.22 12.1 1.2 3.2 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 GAX19812.1 - 0.11 12.7 11.6 2.7 8.2 1.2 3.4 3 2 1 5 5 4 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 GAX19812.1 - 1.3 9.8 7.0 4 8.3 1.2 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain SIS PF01380.22 GAX19814.1 - 5.8e-32 110.3 1.2 4.1e-15 55.8 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAX19814.1 - 1.4e-23 83.6 0.1 2.9e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX19814.1 - 3.9e-15 55.8 0.0 1.1e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAX19814.1 - 9.4e-06 24.7 0.1 2.1e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II bact-PGI_C PF10432.9 GAX19814.1 - 0.02 14.9 0.0 0.4 10.7 0.0 3.0 2 1 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain Toprim_3 PF13362.6 GAX19814.1 - 0.28 11.5 3.0 3.4 8.1 0.6 3.6 4 0 0 4 4 4 0 Toprim domain Oxidored_q3 PF00499.20 GAX19815.1 - 0.0084 15.8 0.9 6 6.6 0.0 2.3 1 1 0 2 2 2 2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 BPD_transp_2 PF02653.16 GAX19815.1 - 1.7 7.7 6.8 3.3 6.8 6.8 1.6 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Peptidase_M8 PF01457.16 GAX19817.1 - 1.6e-23 83.2 0.0 1.2e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Leishmanolysin DUF2889 PF11136.8 GAX19817.1 - 0.0051 17.1 0.0 4.8 7.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2889) SprT-like PF10263.9 GAX19817.1 - 0.2 11.5 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 SprT-like family DUF3810 PF12725.7 GAX19817.1 - 0.26 10.6 0.3 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Peptidase_M8 PF01457.16 GAX19818.1 - 1.1e-07 30.9 0.0 2.3e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 GAX19819.1 - 1.4e-07 30.6 0.0 2.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin PI3K_1B_p101 PF10486.9 GAX19819.1 - 0.12 10.1 10.2 0.18 9.5 10.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SAPS PF04499.15 GAX19819.1 - 5.2 5.7 10.8 13 4.4 10.8 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_M8 PF01457.16 GAX19820.1 - 8.5e-11 41.2 0.0 1.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin RecA PF00154.21 GAX19821.1 - 7.4e-124 412.4 0.2 9.8e-124 412.0 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 GAX19821.1 - 5.5e-10 38.9 0.4 3.6e-09 36.3 0.4 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 GAX19821.1 - 2.4e-07 30.3 2.1 4.6e-06 26.2 0.5 2.9 2 1 0 2 2 2 1 KaiC AAA_24 PF13479.6 GAX19821.1 - 5.1e-06 26.4 0.0 8.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAX19821.1 - 3.8e-05 23.7 0.0 8.4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 GAX19821.1 - 0.00076 19.1 2.4 0.03 13.9 0.8 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX19821.1 - 0.0011 19.4 0.6 0.0043 17.5 0.2 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 GAX19821.1 - 0.0028 18.1 0.0 0.0061 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAX19821.1 - 0.036 14.1 0.0 0.68 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAX19821.1 - 0.055 14.0 0.1 0.39 11.2 0.1 2.3 1 1 0 1 1 1 0 ABC transporter AAA_35 PF14516.6 GAX19821.1 - 0.062 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.14 GAX19821.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_M8 PF01457.16 GAX19822.1 - 2.6e-10 39.6 0.0 4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 GAX19822.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Matrixin Peptidase_M8 PF01457.16 GAX19823.1 - 6.9e-14 51.4 0.0 1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 GAX19823.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 Matrixin UPF0016 PF01169.19 GAX19824.1 - 1.4e-35 121.4 27.1 2.9e-20 72.4 6.8 2.8 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 DSPn PF14671.6 GAX19828.1 - 1.1e-34 119.8 0.1 2.6e-27 96.0 0.0 2.7 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 GAX19828.1 - 1.3e-10 41.2 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX19828.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAX19828.1 - 0.0035 17.5 0.1 0.0075 16.4 0.0 1.5 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAX19828.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family NFRKB_winged PF14465.6 GAX19830.1 - 0.091 13.0 0.3 0.23 11.6 0.3 1.7 1 0 0 1 1 1 0 NFRKB Winged Helix-like DUF5494 PF17598.2 GAX19830.1 - 0.16 12.1 0.3 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5494) HhH-GPD PF00730.25 GAX19831.1 - 4.1e-19 69.0 0.0 8.5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 GAX19831.1 - 6.8e-14 51.8 2.4 3.2e-12 46.4 0.2 3.1 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.23 GAX19831.1 - 3.9e-07 29.6 0.0 1.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SAM_1 PF00536.30 GAX19831.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF3586 PF12131.8 GAX19834.1 - 0.024 14.9 1.3 0.13 12.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) RVT_2 PF07727.14 GAX19836.1 - 7.6e-14 51.9 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX19836.1 - 0.0013 18.9 0.0 0.0035 17.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Mem_trans PF03547.18 GAX19839.1 - 0.087 11.2 0.7 0.11 10.9 0.7 1.1 1 0 0 1 1 1 0 Membrane transport protein Chorion_2 PF03964.15 GAX19839.1 - 0.17 12.8 1.2 0.36 11.7 1.2 1.5 1 1 0 1 1 1 0 Chorion family 2 FAD_binding_7 PF03441.14 GAX19840.1 - 2.6e-43 147.9 1.7 4.2e-43 147.2 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAX19840.1 - 1.7e-27 96.4 0.4 3.1e-27 95.6 0.4 1.4 1 0 0 1 1 1 1 DNA photolyase Spermine_synth PF01564.17 GAX19841.1 - 2e-33 115.4 0.0 3.5e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 GAX19841.1 - 1.2e-19 70.5 0.0 4.5e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine decarboxylase Methyltransf_12 PF08242.12 GAX19841.1 - 7.3e-05 23.5 0.0 0.00026 21.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX19841.1 - 0.015 16.0 0.0 0.037 14.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Bromo_TP PF07524.13 GAX19842.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Sad1_UNC PF07738.13 GAX19843.1 - 2.1e-25 89.2 0.1 3.6e-25 88.5 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 GAX19843.1 - 1e-07 32.1 0.4 2.4e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain ACP PF06857.11 GAX19843.1 - 0.13 12.6 0.1 4 7.7 0.1 2.5 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) BCIP PF13862.6 GAX19843.1 - 0.27 11.0 0.9 8.7 6.1 0.1 2.2 2 0 0 2 2 2 0 p21-C-terminal region-binding protein HSF_DNA-bind PF00447.17 GAX19845.1 - 3.1e-19 69.4 0.0 5.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3909 PF13077.6 GAX19846.1 - 0.15 12.3 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) RVT_2 PF07727.14 GAX19847.1 - 1.2e-18 67.6 0.1 2.9e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Beta-Casp PF10996.8 GAX19850.1 - 4.6e-30 104.2 0.0 2.2e-29 102.0 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain CPSF73-100_C PF11718.8 GAX19850.1 - 6.8e-30 104.2 0.0 1.3e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_6 PF16661.5 GAX19850.1 - 3.7e-17 62.4 0.0 1.3e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX19850.1 - 9e-15 55.2 0.2 1.9e-14 54.1 0.2 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 GAX19850.1 - 1.4e-13 50.5 0.0 3.2e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 GAX19850.1 - 2.2e-08 33.9 0.1 6.7e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAX19850.1 - 4.4e-06 26.7 0.1 1.2e-05 25.2 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GAX19850.1 - 0.00016 21.0 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Gemin6 PF06372.12 GAX19850.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Gemin6 protein Copine PF07002.16 GAX19852.1 - 5.7e-53 179.6 0.0 7.8e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX19852.1 - 7e-18 64.8 0.0 2e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX19852.1 - 5.3e-07 30.0 0.0 1.4e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 vWA found in TerF C terminus UAE_UbL PF14732.6 GAX19852.1 - 0.089 13.4 0.2 0.21 12.2 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DapB_C PF05173.14 GAX19853.1 - 1.6e-19 70.1 0.2 3.3e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 GAX19853.1 - 5.6e-11 42.6 0.0 1.3e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Nucleoporin_C PF03177.14 GAX19853.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal Peptidase_S9 PF00326.21 GAX19854.1 - 5.7e-39 133.8 0.0 1.1e-38 132.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAX19854.1 - 5.2e-10 39.4 0.2 3.6e-07 30.1 0.3 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAX19854.1 - 3.7e-07 30.2 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 GAX19854.1 - 1e-06 28.5 0.0 1.1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAX19854.1 - 3.7e-06 26.4 0.0 0.00026 20.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 GAX19854.1 - 1.2e-05 24.2 0.0 2.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 GAX19854.1 - 0.00099 18.8 0.0 0.19 11.3 0.0 2.7 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 GAX19854.1 - 0.023 14.6 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ku PF02735.16 GAX19855.1 - 1.2e-21 77.4 0.0 2.7e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAX19855.1 - 4.5e-09 36.4 0.7 8.7e-09 35.4 0.7 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.6 GAX19855.1 - 1.3e-05 25.7 0.8 0.00015 22.3 0.8 2.6 1 1 0 1 1 1 1 von Willebrand factor type A domain PGK PF00162.19 GAX19856.1 - 6e-153 509.3 0.8 7.6e-153 508.9 0.8 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase HTH_24 PF13412.6 GAX19856.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 GAX19856.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain WD40 PF00400.32 GAX19857.1 - 5.8e-58 191.5 25.6 4.4e-08 33.6 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX19857.1 - 1.6e-15 57.1 3.1 0.033 14.5 0.0 6.1 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 GAX19857.1 - 4.9e-09 36.6 0.0 1.5e-08 35.0 0.0 1.8 1 1 1 2 2 2 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 GAX19857.1 - 5.1e-06 25.7 0.8 2.8 6.8 0.0 5.1 3 2 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAX19857.1 - 1.6e-05 23.8 7.2 0.038 12.6 0.3 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 GAX19857.1 - 4.1e-05 23.6 0.2 0.13 12.2 0.0 3.3 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A HMA PF00403.26 GAX19858.1 - 0.00085 19.7 0.7 0.0021 18.5 0.7 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Jas PF16135.5 GAX19858.1 - 1.7 8.9 0.0 1.7 8.9 0.0 3.1 3 0 0 3 3 3 0 TPL-binding domain in jasmonate signalling PIG-U PF06728.13 GAX19859.1 - 3.1e-47 161.5 28.7 4e-47 161.1 28.7 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U CtsR_C PF17727.1 GAX19861.1 - 0.027 14.6 0.5 0.038 14.1 0.5 1.3 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain Ran-binding PF05508.11 GAX19861.1 - 0.036 13.0 0.2 0.047 12.7 0.2 1.1 1 0 0 1 1 1 0 RanGTP-binding protein DUF1664 PF07889.12 GAX19862.1 - 0.018 15.0 0.3 0.027 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2570 PF10828.8 GAX19862.1 - 0.04 13.7 0.2 0.053 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Chordopox_RPO7 PF05864.12 GAX19862.1 - 0.1 12.9 0.3 0.8 10.0 0.1 2.3 2 1 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) FlaC_arch PF05377.11 GAX19862.1 - 0.12 12.8 0.3 1.2 9.5 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RraA-like PF03737.15 GAX19864.1 - 1.8e-40 138.5 0.1 2.7e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA Flavi_propep PF01570.17 GAX19864.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide Choline_transpo PF04515.12 GAX19865.1 - 1.5e-67 228.2 30.7 1.5e-67 228.2 30.7 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter 2OG-FeII_Oxy_3 PF13640.6 GAX19865.1 - 7.5e-10 39.6 0.0 1.9e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 GAX19866.1 - 1e-14 54.6 4.0 0.04 14.8 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX19866.1 - 0.00028 21.1 0.0 4.2 7.7 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RNB PF00773.19 GAX19867.1 - 1.6e-53 182.1 0.0 2.6e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 RNB domain EPSP_synthase PF00275.20 GAX19868.1 - 5.3e-133 443.7 0.0 6.1e-133 443.5 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Tcf25 PF04910.14 GAX19869.1 - 4.3e-37 128.0 0.0 6.7e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF3024 PF11225.8 GAX19869.1 - 0.098 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Sel1 PF08238.12 GAX19870.1 - 3.5e-16 59.3 4.1 6.2e-07 29.9 0.2 3.7 4 0 0 4 4 4 3 Sel1 repeat Pox_A_type_inc PF04508.12 GAX19870.1 - 0.16 11.9 0.6 0.3 11.0 0.6 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DEAD PF00270.29 GAX19871.1 - 4e-33 114.6 0.0 7.2e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX19871.1 - 6.7e-26 90.8 0.0 3.6e-25 88.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA PF00004.29 GAX19871.1 - 0.13 12.7 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps53_N PF04100.12 GAX19872.1 - 2.7e-58 197.7 11.3 1.5e-31 109.7 4.4 3.2 2 1 1 3 3 3 3 Vps53-like, N-terminal COG7 PF10191.9 GAX19872.1 - 4.5e-05 21.9 5.3 0.0026 16.1 0.1 2.6 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) DUF2451 PF10474.9 GAX19872.1 - 0.00025 20.9 0.7 0.002 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) COG5 PF10392.9 GAX19872.1 - 0.0043 17.2 5.3 0.0043 17.2 5.3 2.0 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Tropomyosin_1 PF12718.7 GAX19872.1 - 0.0054 16.9 5.0 0.021 15.0 5.0 2.0 1 0 0 1 1 1 1 Tropomyosin like COG2 PF06148.11 GAX19872.1 - 0.01 15.9 2.8 0.01 15.9 2.8 3.0 4 0 0 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 GAX19872.1 - 0.025 13.9 5.5 0.0086 15.4 2.6 1.6 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF1664 PF07889.12 GAX19872.1 - 0.15 12.1 12.7 0.96 9.5 6.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) FUSC PF04632.12 GAX19872.1 - 0.18 10.3 7.0 0.33 9.4 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRE1 PF08647.11 GAX19872.1 - 0.45 10.6 11.1 0.17 12.0 7.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase LXG PF04740.12 GAX19872.1 - 0.53 10.0 7.3 1.8 8.2 3.8 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily CENP-F_leu_zip PF10473.9 GAX19872.1 - 0.63 10.1 8.9 0.64 10.0 6.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MnmE_helical PF12631.7 GAX19872.1 - 0.68 10.1 3.6 2 8.5 1.9 2.4 2 0 0 2 2 2 0 MnmE helical domain Spc7 PF08317.11 GAX19872.1 - 1.2 7.9 10.3 0.23 10.3 6.5 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4337 PF14235.6 GAX19872.1 - 2.2 8.4 7.1 1.5 8.9 4.9 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) Laminin_II PF06009.12 GAX19872.1 - 2.2 8.3 9.9 5.7 7.0 5.0 2.5 2 0 0 2 2 2 0 Laminin Domain II KxDL PF10241.9 GAX19872.1 - 2.4 8.5 11.5 12 6.2 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein CREPT PF16566.5 GAX19872.1 - 4.5 7.4 8.7 2.2 8.5 5.4 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 GAX19872.1 - 4.8 7.4 7.4 3.7 7.7 4.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1690 PF07956.11 GAX19872.1 - 6.1 7.3 12.4 7.7 6.9 4.6 3.2 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) NPV_P10 PF05531.12 GAX19872.1 - 8.4 6.9 9.9 31 5.1 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein AP2 PF00847.20 GAX19873.1 - 0.00014 22.0 1.2 0.00014 22.0 1.2 2.2 3 0 0 3 3 3 1 AP2 domain HNH_3 PF13392.6 GAX19873.1 - 0.054 13.3 0.8 0.12 12.2 0.4 1.7 2 0 0 2 2 2 0 HNH endonuclease Cas_St_Csn2 PF16813.5 GAX19873.1 - 0.12 11.4 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St Sec6 PF06046.13 GAX19874.1 - 7.6e-08 31.2 2.5 7.6e-08 31.2 2.5 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 SRA1 PF07304.11 GAX19874.1 - 0.06 13.1 0.2 3.5 7.4 0.1 2.6 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Maf1 PF09174.10 GAX19874.1 - 0.075 13.2 0.5 0.21 11.7 0.2 1.8 1 1 1 2 2 2 0 Maf1 regulator YlqD PF11068.8 GAX19874.1 - 5.9 7.3 9.1 0.67 10.3 0.3 2.9 3 0 0 3 3 3 0 YlqD protein ADH_zinc_N PF00107.26 GAX19875.1 - 5.2e-17 62.0 0.0 9.1e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX19875.1 - 5.1e-08 32.8 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAX19875.1 - 2.1e-06 28.8 0.0 4.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DNA_pol3_delta2 PF13177.6 GAX19876.1 - 1e-09 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 GAX19876.1 - 3.5e-06 27.4 0.0 1.4e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 GAX19876.1 - 0.00046 20.2 0.0 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 GAX19876.1 - 0.0034 17.5 0.0 0.38 10.9 0.1 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 GAX19876.1 - 0.0062 17.0 0.2 0.021 15.3 0.2 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX19876.1 - 0.0094 16.3 0.0 0.039 14.3 0.0 2.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GAX19876.1 - 0.013 16.0 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 GAX19876.1 - 0.024 14.5 0.5 1.8 8.3 0.4 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein RuvB_N PF05496.12 GAX19876.1 - 0.025 14.3 0.0 0.89 9.3 0.0 2.8 2 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 GAX19876.1 - 0.026 14.4 0.0 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 GAX19876.1 - 0.045 14.3 0.0 0.079 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 GAX19876.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAX19876.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX19876.1 - 0.24 11.6 1.6 9.9 6.4 0.4 3.4 1 1 1 3 3 3 0 AAA domain ANAPC_CDC26 PF10471.9 GAX19877.1 - 2.4e-09 37.9 0.1 3e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 adh_short PF00106.25 GAX19879.1 - 3.7e-48 163.6 0.0 4.9e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX19879.1 - 8e-38 130.3 0.0 1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX19879.1 - 1.2e-14 54.7 0.0 1.7e-14 54.1 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX19879.1 - 2.9e-07 30.2 0.0 5.4e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAX19879.1 - 9.1e-07 29.4 0.1 2.1e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 GAX19879.1 - 4.3e-06 26.4 0.1 5.7e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 GAX19879.1 - 6.6e-05 22.9 0.3 0.00015 21.7 0.3 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX19879.1 - 0.00012 21.5 0.0 0.004 16.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 GAX19879.1 - 0.00014 21.9 0.9 0.0005 20.0 1.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAX19879.1 - 0.00015 22.0 0.1 0.00023 21.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 GAX19879.1 - 0.00039 19.6 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain ApbA PF02558.16 GAX19879.1 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 GAX19879.1 - 0.0021 18.2 0.2 0.0033 17.5 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 GAX19879.1 - 0.0022 17.2 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 GAX19879.1 - 0.0057 16.0 0.6 0.022 14.1 0.1 2.1 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_4 PF07993.12 GAX19879.1 - 0.0063 15.7 0.1 1.5 7.9 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein DFP PF04127.15 GAX19879.1 - 0.0084 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 GAX19879.1 - 0.016 14.8 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_2 PF03446.15 GAX19879.1 - 0.053 13.7 0.1 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 GAX19879.1 - 0.055 13.9 0.1 0.091 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DapB_N PF01113.20 GAX19879.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PHD PF00628.29 GAX19881.1 - 9.5e-10 38.2 8.7 2e-09 37.2 8.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAX19881.1 - 0.00096 18.7 1.3 0.0022 17.5 1.3 1.6 1 0 0 1 1 1 1 PHD-finger Cue1_U7BR PF18499.1 GAX19881.1 - 0.24 11.4 1.0 3.1 7.9 0.2 2.4 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 zf-HC5HC2H PF13771.6 GAX19881.1 - 0.41 10.9 7.5 1 9.6 7.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Adap_comp_sub PF00928.21 GAX19882.1 - 1.1e-08 34.7 0.2 1.7e-07 30.9 0.2 2.1 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Myco_19_kDa PF05481.12 GAX19882.1 - 0.14 12.5 0.1 0.55 10.5 0.0 2.0 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen H_lectin PF09458.10 GAX19883.1 - 0.2 11.9 0.1 0.31 11.3 0.1 1.3 1 0 0 1 1 1 0 H-type lectin domain Hydrolase_4 PF12146.8 GAX19884.1 - 9.7e-10 38.1 0.0 9.1e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX19884.1 - 1.1e-09 38.3 0.0 0.0025 17.5 0.0 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX19884.1 - 2e-08 35.1 0.4 4.3e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAX19884.1 - 5.7e-06 26.3 0.0 2.7e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 GAX19884.1 - 0.00013 22.0 0.0 0.12 12.3 0.0 2.5 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 GAX19884.1 - 0.00014 21.6 0.0 0.026 14.2 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 GAX19884.1 - 0.00069 19.1 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family UPF0227 PF05728.12 GAX19884.1 - 0.0024 17.8 0.0 0.0067 16.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DAGAT PF03982.13 GAX19884.1 - 0.0097 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GAX19884.1 - 0.031 13.9 0.0 0.26 10.9 0.0 2.2 1 1 0 1 1 1 0 Acyltransferase DLH PF01738.18 GAX19884.1 - 0.035 13.7 0.0 1.9 8.0 0.0 2.8 3 0 0 3 3 3 0 Dienelactone hydrolase family Ser_hydrolase PF06821.13 GAX19884.1 - 0.13 12.1 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.13 GAX19884.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Say1_Mug180 PF10340.9 GAX19884.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase WD40 PF00400.32 GAX19885.1 - 5.5e-26 90.3 11.3 2.8e-06 27.9 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX19885.1 - 2.2e-09 37.5 0.4 1.1e-05 25.6 0.0 4.1 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX19885.1 - 0.00012 21.6 3.1 0.0077 15.6 0.1 3.4 1 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 GAX19885.1 - 0.0025 16.8 1.0 0.13 11.2 0.0 3.1 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAX19885.1 - 0.007 15.1 1.4 1.8 7.1 0.0 3.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Frtz PF11768.8 GAX19885.1 - 0.017 13.4 0.4 0.98 7.7 0.0 2.6 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_C97 PF05903.14 GAX19886.1 - 6.6e-26 91.0 0.0 2.6e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 PPPDE putative peptidase domain ISN1 PF06437.11 GAX19887.1 - 3.2e-93 312.9 0.0 4.1e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase CDP-OH_P_transf PF01066.21 GAX19888.1 - 2.6e-15 56.9 0.1 2.6e-15 56.9 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SNF2_N PF00176.23 GAX19889.1 - 1.5e-71 241.0 0.7 1.5e-71 241.0 0.7 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAX19889.1 - 2.1e-34 118.0 0.3 2.1e-34 118.0 0.3 2.9 2 1 0 2 2 2 1 SLIDE Helicase_C PF00271.31 GAX19889.1 - 2.1e-18 66.7 0.0 8.3e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HMG_box PF00505.19 GAX19889.1 - 5.4e-12 45.9 8.1 2.3e-08 34.3 1.3 3.6 2 0 0 2 2 2 2 HMG (high mobility group) box ResIII PF04851.15 GAX19889.1 - 4.4e-11 43.1 0.0 4.4e-11 43.1 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HMG_box_2 PF09011.10 GAX19889.1 - 4.2e-08 33.7 2.7 4.2e-08 33.7 2.7 3.8 3 0 0 3 3 2 2 HMG-box domain DEAD PF00270.29 GAX19889.1 - 9e-06 25.6 0.0 4.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAX19889.1 - 0.008 15.4 0.0 0.008 15.4 0.0 2.9 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Mst1_SARAH PF11629.8 GAX19889.1 - 0.0096 16.0 0.5 0.034 14.2 0.5 1.9 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 PGK PF00162.19 GAX19889.1 - 0.1 11.5 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoglycerate kinase TssO PF17561.2 GAX19889.1 - 0.3 11.2 3.8 1.2 9.3 3.8 2.0 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF3782 PF12644.7 GAX19889.1 - 5.9 7.1 8.3 11 6.2 1.6 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) WW PF00397.26 GAX19890.1 - 1.5e-12 47.4 0.3 4.9e-12 45.7 0.3 2.0 1 0 0 1 1 1 1 WW domain Sec16_C PF12931.7 GAX19890.1 - 5.7e-12 45.9 1.6 2e-10 40.8 1.6 2.9 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 GAX19890.1 - 2e-07 31.6 11.4 0.043 14.7 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat TPR_1 PF00515.28 GAX19890.1 - 0.073 12.9 0.1 17 5.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat WHAMM-JMY_N PF15920.5 GAX19890.1 - 0.11 12.4 0.5 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 N-terminal of Junction-mediating and WASP homolog-associated DUF285 PF03382.14 GAX19891.1 - 4.7e-110 362.1 70.5 2.5e-30 104.7 8.4 5.2 2 2 3 5 5 5 5 Mycoplasma protein of unknown function, DUF285 CagS PF16707.5 GAX19893.1 - 0.018 15.0 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori DUF4080 PF13311.6 GAX19893.1 - 0.059 13.6 0.0 0.06 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) SAP PF02037.27 GAX19894.1 - 0.00041 20.0 0.4 0.00099 18.8 0.4 1.6 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 GAX19894.1 - 0.011 15.1 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 LETM1-like protein T4SS PF07996.11 GAX19894.1 - 0.017 15.5 1.9 0.063 13.7 0.3 2.3 2 1 0 2 2 2 0 Type IV secretion system proteins MCD_N PF17408.2 GAX19894.1 - 0.074 13.2 0.3 0.24 11.6 0.3 1.9 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain SlyX PF04102.12 GAX19894.1 - 2.9 8.6 10.4 2.7 8.7 0.9 3.9 3 1 0 3 3 3 0 SlyX Asn_synthase PF00733.21 GAX19895.1 - 9.1e-89 298.6 0.1 1.6e-54 185.9 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GAX19895.1 - 1e-37 128.8 0.0 1.6e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAX19895.1 - 3.2e-29 101.8 0.0 5e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAX19895.1 - 3.3e-12 46.4 0.0 6.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 GAX19895.1 - 0.0056 15.8 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD synthase UbiA PF01040.18 GAX19896.1 - 1.6e-31 109.5 12.1 1.6e-31 109.5 12.1 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family SPT16 PF08644.11 GAX19898.1 - 2.6e-51 173.8 0.1 2.6e-51 173.8 0.1 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 GAX19898.1 - 3.8e-37 127.6 0.0 1.3e-36 125.8 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 GAX19898.1 - 2.7e-28 99.1 0.0 5.7e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 GAX19898.1 - 3.9e-13 49.6 0.1 8.6e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like BP28CT PF08146.12 GAX19898.1 - 0.13 12.1 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 BP28CT (NUC211) domain NPR2 PF06218.11 GAX19899.1 - 2.6e-49 168.2 0.0 9.2e-47 159.8 0.0 3.1 1 1 0 1 1 1 1 Nitrogen permease regulator 2 AAA_26 PF13500.6 GAX19900.1 - 7.7e-36 123.8 0.0 1e-35 123.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX19900.1 - 9.2e-07 29.0 0.0 2.3e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 GAX19900.1 - 0.0076 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 DRTGG domain AAA_31 PF13614.6 GAX19900.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain CBP_BcsR PF10945.8 GAX19900.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR ArsA_ATPase PF02374.15 GAX19900.1 - 0.2 10.8 0.2 0.85 8.7 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase Vps51 PF08700.11 GAX19901.1 - 0.00014 21.9 0.7 0.00045 20.3 0.7 2.0 1 0 0 1 1 1 1 Vps51/Vps67 EF-hand_8 PF13833.6 GAX19901.1 - 0.0099 15.7 0.1 0.031 14.1 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX19901.1 - 0.02 14.4 0.2 0.078 12.6 0.2 2.1 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 GAX19901.1 - 0.18 11.8 0.2 0.64 10.1 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain YkyA PF10368.9 GAX19901.1 - 0.45 10.2 5.4 3 7.5 0.6 2.8 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein ER_lumen_recept PF00810.18 GAX19902.1 - 9.6e-34 117.3 2.3 1.9e-33 116.3 2.3 1.5 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 GAX19902.1 - 0.068 13.0 5.0 0.37 10.6 0.1 3.4 3 0 0 3 3 3 0 PQ loop repeat TB2_DP1_HVA22 PF03134.19 GAX19903.1 - 1.1e-29 102.2 7.4 1.6e-29 101.7 7.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 GAX19903.1 - 0.071 13.3 5.1 2.7 8.3 2.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Halogen_Hydrol PF10112.9 GAX19903.1 - 0.97 9.4 4.0 0.28 11.2 0.8 1.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RPA_C PF08784.11 GAX19904.1 - 3.7e-08 34.0 1.1 7.6e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 GAX19904.1 - 0.00013 21.8 0.1 0.00022 21.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2666 PF10869.8 GAX19904.1 - 0.016 15.4 0.0 0.042 14.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF4817 PF16087.5 GAX19904.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Keratin_2_head PF16208.5 GAX19904.1 - 5 7.2 26.6 2.1 8.5 21.3 2.2 2 0 0 2 2 2 0 Keratin type II head PCI PF01399.27 GAX19905.1 - 6.5e-23 81.3 0.6 1.6e-22 80.0 0.6 1.7 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 GAX19905.1 - 0.015 15.3 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_12 PF13424.6 GAX19905.1 - 0.068 13.5 0.6 0.78 10.1 0.1 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Rota_NS6 PF04866.12 GAX19905.1 - 0.46 10.7 2.1 2.3 8.5 0.0 2.9 4 0 0 4 4 4 0 Rotavirus non-structural protein 6 Arm PF00514.23 GAX19906.1 - 1.2e-41 139.5 23.6 3.2e-10 39.7 0.0 8.5 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAX19906.1 - 5.5e-13 49.1 0.9 1.6e-06 28.4 0.0 5.0 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 GAX19906.1 - 1.2e-11 43.9 1.8 0.52 10.7 0.0 6.5 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.6 GAX19906.1 - 7.3e-08 32.8 6.4 0.071 13.6 0.0 7.1 6 2 3 9 9 9 3 HEAT-like repeat Arm_3 PF16186.5 GAX19906.1 - 0.00059 19.3 0.0 0.083 12.5 0.0 2.7 2 0 0 2 2 2 1 Atypical Arm repeat SR-25 PF10500.9 GAX19906.1 - 0.008 15.8 12.3 0.008 15.8 12.3 2.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DDHD PF02862.17 GAX19906.1 - 0.036 14.2 7.4 0.13 12.4 3.7 2.5 2 0 0 2 2 2 0 DDHD domain DUF2098 PF09871.9 GAX19906.1 - 1.9 8.9 5.7 7.4 7.0 5.7 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) VHL PF01847.16 GAX19907.1 - 0.00029 20.7 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 VHL beta domain Flavoprotein PF02441.19 GAX19908.1 - 5.5e-40 136.7 0.0 8.4e-40 136.1 0.0 1.3 1 1 0 1 1 1 1 Flavoprotein Ribosomal_L30_N PF08079.12 GAX19908.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain LRR_6 PF13516.6 GAX19909.1 - 5.3e-26 88.4 10.5 0.0021 17.9 0.1 10.1 10 0 0 10 10 10 7 Leucine Rich repeat LRR_4 PF12799.7 GAX19909.1 - 1.4e-05 25.3 8.4 0.091 13.2 0.1 6.1 4 3 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX19909.1 - 0.014 15.1 18.3 2.7 7.8 0.1 6.6 4 2 3 7 7 7 0 Leucine rich repeat LRR_1 PF00560.33 GAX19909.1 - 0.029 14.9 6.1 1.5e+02 3.5 0.0 6.9 7 1 0 7 7 7 0 Leucine Rich Repeat UDPGP PF01704.18 GAX19910.1 - 2.1e-54 184.8 0.0 2.7e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 GAX19910.1 - 0.0025 18.2 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NARP1 PF12569.8 GAX19911.1 - 8e-132 440.8 12.6 2.9e-131 438.9 5.1 3.1 2 2 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 GAX19911.1 - 5.4e-16 58.9 1.6 0.00024 21.5 0.1 6.5 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX19911.1 - 2.5e-15 55.9 3.9 0.012 16.4 0.0 7.8 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX19911.1 - 1.3e-14 53.1 16.4 1.8e-06 27.6 0.2 8.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX19911.1 - 2.1e-11 43.1 1.7 1.3e-05 25.0 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX19911.1 - 8.8e-11 41.1 13.8 4.9e-06 26.1 0.3 7.2 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX19911.1 - 5.3e-09 36.6 1.8 0.12 13.0 0.0 6.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX19911.1 - 8.7e-09 35.6 3.8 0.074 13.3 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAX19911.1 - 5.3e-08 32.7 2.4 0.0076 16.6 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX19911.1 - 8.8e-08 31.7 2.4 5.3e-06 26.0 0.5 3.9 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 GAX19911.1 - 1.6e-05 25.0 7.4 0.049 13.9 0.7 4.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 GAX19911.1 - 2.1e-05 24.5 6.7 0.05 13.7 0.3 5.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 GAX19911.1 - 2.7e-05 24.2 0.1 0.48 10.6 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX19911.1 - 0.00026 21.4 14.7 3.7 8.4 0.1 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX19911.1 - 0.0003 20.6 2.2 0.01 15.8 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX19911.1 - 0.026 13.7 0.9 0.28 10.4 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAX19911.1 - 0.034 14.2 5.6 5.4 7.1 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat NADH5_C PF06455.11 GAX19911.1 - 0.14 11.8 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus TPR_10 PF13374.6 GAX19911.1 - 0.44 10.5 1.8 3.3 7.7 0.2 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat ANTH PF07651.16 GAX19912.1 - 2.5e-08 33.3 0.0 4.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 GAX19912.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 ENTH domain TP_methylase PF00590.20 GAX19913.1 - 6.2e-25 88.4 0.1 1.3e-24 87.3 0.1 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TLD PF07534.16 GAX19914.1 - 4.5e-22 78.8 0.0 6.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 TLD UFD1 PF03152.14 GAX19915.1 - 2.2e-21 76.1 0.0 2.4e-11 43.4 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 GAX19915.1 - 1.2e-13 51.1 0.1 2.6e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 UBX domain DHHC PF01529.20 GAX19916.1 - 4.4e-14 52.7 3.3 4.7e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase zinc_ribbon_2 PF13240.6 GAX19916.1 - 0.018 14.8 0.5 0.095 12.5 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF3464 PF11947.8 GAX19916.1 - 0.067 12.9 1.2 0.17 11.7 1.2 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SPX PF03105.19 GAX19917.1 - 4.7e-10 39.9 15.6 2.7e-09 37.4 0.9 2.8 2 1 1 3 3 3 2 SPX domain DUF3958 PF13125.6 GAX19917.1 - 0.062 13.5 1.0 0.18 12.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) WD40 PF00400.32 GAX19918.1 - 8.7e-14 51.7 5.4 2.6e-06 28.1 0.0 4.9 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX19918.1 - 3.5e-10 40.0 0.0 0.0056 17.0 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX19918.1 - 0.0057 17.1 0.0 1.5 9.4 0.0 3.7 4 1 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.11 GAX19918.1 - 0.0077 15.0 0.0 0.032 13.0 0.0 1.9 2 0 0 2 2 2 1 Nup133 N terminal like SpoU_methylase PF00588.19 GAX19919.1 - 7.2e-07 29.5 0.0 5.7e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 SpoU rRNA Methylase family Bac_globin PF01152.21 GAX19920.1 - 9.4e-07 29.0 0.0 1.7e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial-like globin DUF4420 PF14390.6 GAX19920.1 - 0.01 15.1 0.0 0.063 12.5 0.0 1.9 1 1 1 2 2 2 0 Putative PD-(D/E)XK family member, (DUF4420) PPR_2 PF13041.6 GAX19921.1 - 4.3e-07 30.0 0.1 2.2 8.6 0.0 5.9 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.6 GAX19921.1 - 2.7e-05 24.2 0.0 0.067 13.3 0.0 3.8 4 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX19921.1 - 3.4e-05 23.3 0.6 0.082 12.3 0.1 3.2 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP tRNA_synthFbeta PF17759.1 GAX19921.1 - 0.11 11.9 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain FAD_binding_3 PF01494.19 GAX19922.1 - 3.1e-51 174.7 0.0 5.8e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 GAX19922.1 - 3e-07 29.8 0.0 1.2e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 Squalene epoxidase zf-C3H1 PF10650.9 GAX19922.1 - 2.4e-06 27.1 0.9 4.4e-06 26.3 0.9 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain LRR_8 PF13855.6 GAX19922.1 - 0.00034 20.3 1.4 0.1 12.4 0.6 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX19922.1 - 0.0017 18.7 1.2 0.56 10.7 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Lycopene_cycl PF05834.12 GAX19922.1 - 0.0076 15.3 0.0 6.1 5.8 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAX19922.1 - 0.1 11.8 0.0 7.4 5.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pro_isomerase PF00160.21 GAX19923.1 - 4.5e-40 137.5 0.0 6.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD muHD PF10291.9 GAX19924.1 - 0.031 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 GAX19924.1 - 0.031 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Adaptor complexes medium subunit family KfrB PF18790.1 GAX19925.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 KfrB protein SNase PF00565.17 GAX19926.1 - 0.13 12.7 0.0 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Staphylococcal nuclease homologue ANAPC4_WD40 PF12894.7 GAX19928.1 - 0.00011 22.5 0.0 0.23 11.8 0.0 3.8 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 GAX19928.1 - 0.0013 18.5 0.1 0.84 9.3 0.0 3.1 2 1 1 3 3 3 1 TUP1-like enhancer of split BBS2_Mid PF14783.6 GAX19928.1 - 0.007 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 GAX19928.1 - 0.0097 15.3 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain WD40 PF00400.32 GAX19928.1 - 0.023 15.6 9.3 0.29 12.1 0.1 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat Flavokinase PF01687.17 GAX19929.1 - 2e-26 92.5 0.0 2.6e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PSII_BNR PF14870.6 GAX19930.1 - 8.1e-126 419.4 1.9 9.6e-126 419.1 1.9 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 GAX19930.1 - 2.9e-09 35.6 5.0 0.66 10.2 0.0 5.6 5 0 0 5 5 5 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 GAX19930.1 - 1.6e-06 27.2 0.1 0.0064 15.3 0.0 3.2 2 1 0 3 3 3 2 Sortilin, neurotensin receptor 3, DUF4185 PF13810.6 GAX19930.1 - 0.03 13.6 1.8 1.4 8.1 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4185) Fez1 PF06818.15 GAX19931.1 - 7.4e-05 23.3 12.2 7.4e-05 23.3 12.2 4.1 1 1 2 3 3 3 1 Fez1 DUF3391 PF11871.8 GAX19931.1 - 0.0062 17.1 0.5 0.0062 17.1 0.5 5.0 4 1 0 4 4 4 1 Domain of unknown function (DUF3391) UPF0242 PF06785.11 GAX19931.1 - 0.013 15.6 47.1 0.24 11.5 17.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Val_tRNA-synt_C PF10458.9 GAX19931.1 - 0.017 15.4 0.3 0.017 15.4 0.3 5.1 6 0 0 6 6 6 0 Valyl tRNA synthetase tRNA binding arm Golgin_A5 PF09787.9 GAX19931.1 - 0.047 13.2 53.1 0.013 15.0 8.7 3.2 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF4407 PF14362.6 GAX19931.1 - 1.4 8.2 42.7 0.083 12.2 7.7 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Ribosomal_L10 PF00466.20 GAX19931.1 - 2.2 8.4 8.8 11 6.3 0.2 3.3 3 1 0 3 3 3 0 Ribosomal protein L10 Spc7 PF08317.11 GAX19931.1 - 6 5.7 62.3 0.17 10.8 13.6 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein Gtr1_RagA PF04670.12 GAX19932.1 - 4.6e-51 173.4 0.0 1.1e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region NifT PF06988.11 GAX19932.1 - 0.00067 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 NifT/FixU protein AAA_14 PF13173.6 GAX19932.1 - 0.093 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.20 GAX19933.1 - 6.8e-16 58.1 0.0 1.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 GAX19933.1 - 4.4e-13 49.0 0.0 1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 PUB domain Thioredoxin_8 PF13905.6 GAX19933.1 - 0.00023 21.4 0.0 0.00054 20.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GAX19933.1 - 0.0077 16.4 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX19933.1 - 0.074 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 GAX19933.1 - 0.17 12.1 0.0 0.86 9.9 0.0 2.2 1 0 0 1 1 1 0 Glutaredoxin Glyco_trans_1_2 PF13524.6 GAX19934.1 - 3.1e-09 37.1 0.2 8.1e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 FAM209 PF15206.6 GAX19934.1 - 0.033 14.0 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 FAM209 family DnaJ PF00226.31 GAX19935.1 - 6.3e-10 39.0 0.1 1.5e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 GAX19936.1 - 1.3e-49 169.0 0.0 1.8e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19936.1 - 7.5e-25 87.7 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX19936.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L31e PF01198.19 GAX19937.1 - 3.2e-42 142.7 1.1 3.9e-42 142.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DHquinase_I PF01487.15 GAX19938.1 - 6.4e-23 82.2 0.0 1.8e-21 77.4 0.0 2.6 2 1 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 GAX19938.1 - 6.7e-23 80.8 0.3 3.7e-22 78.4 0.1 2.3 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 GAX19938.1 - 1.9e-11 43.5 0.5 4e-11 42.5 0.5 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain PALP PF00291.25 GAX19938.1 - 0.00018 21.0 0.0 0.014 14.8 0.0 2.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Shikimate_DH PF01488.20 GAX19938.1 - 0.0017 18.4 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAX19938.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAX19938.1 - 0.058 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3506 PF12014.8 GAX19940.1 - 8e-12 45.4 0.0 1.3e-08 34.9 0.0 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3506) DUF4398 PF14346.6 GAX19940.1 - 0.16 12.6 5.7 0.32 11.6 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF3506 PF12014.8 GAX19941.1 - 1e-13 51.5 0.0 9.3e-11 41.9 0.0 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) DEAD PF00270.29 GAX19942.1 - 7.8e-47 159.3 0.0 1.6e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX19942.1 - 7.1e-29 100.4 0.4 6.4e-28 97.3 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX19942.1 - 0.00026 21.0 0.0 0.00026 21.0 0.0 3.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAX19942.1 - 0.089 11.5 0.3 0.72 8.6 0.1 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Phosphodiest PF01663.22 GAX19943.1 - 8.3e-12 45.4 0.8 1.6e-11 44.4 0.2 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 GAX19943.1 - 2.5e-05 23.8 1.0 3.9e-05 23.1 1.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 GAX19943.1 - 0.0041 16.6 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase LTV PF04180.14 GAX19944.1 - 9.5e-10 38.8 12.8 3.7e-05 23.6 0.3 4.0 3 1 0 3 3 3 2 Low temperature viability protein TPR_8 PF13181.6 GAX19945.1 - 6.3 7.3 6.4 1.3 9.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 GAX19946.1 - 4.8e-25 88.2 39.8 4.8e-25 88.2 39.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily C2 PF00168.30 GAX19947.1 - 6.5e-28 97.1 0.0 3.5e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain DUF2229 PF09989.9 GAX19947.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Ribosomal_L20 PF00453.18 GAX19947.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.2 4 0 0 4 4 4 0 Ribosomal protein L20 EMC3_TMCO1 PF01956.16 GAX19947.1 - 1.1 9.0 7.1 2.9 7.6 2.9 2.8 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like COPIIcoated_ERV PF07970.12 GAX19949.1 - 4.9e-24 85.4 0.5 9.1e-24 84.5 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX19949.1 - 4.6e-13 49.3 0.0 1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) C2 PF00168.30 GAX19950.1 - 2e-12 47.3 0.0 5.3e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain PRT_C PF08372.10 GAX19950.1 - 0.0022 17.8 0.2 0.0067 16.2 0.2 1.8 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal AAA_3 PF07726.11 GAX19950.1 - 0.026 14.4 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIG-L PF02585.17 GAX19951.1 - 0.055 14.1 0.0 0.69 10.5 0.0 2.4 2 1 0 2 2 2 0 GlcNAc-PI de-N-acetylase ATG16 PF08614.11 GAX19952.1 - 0.00092 19.5 19.4 0.00092 19.5 19.4 4.1 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) DUF4472 PF14739.6 GAX19952.1 - 0.027 15.2 10.4 0.027 15.2 10.4 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4472) bZIP_1 PF00170.21 GAX19952.1 - 0.028 14.5 0.9 0.028 14.5 0.9 5.1 4 1 2 6 6 6 0 bZIP transcription factor NPV_P10 PF05531.12 GAX19952.1 - 0.12 12.8 16.0 6.2 7.4 0.8 4.9 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Shugoshin_N PF07558.11 GAX19952.1 - 0.57 10.1 0.1 0.57 10.1 0.1 3.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Bcr-Abl_Oligo PF09036.10 GAX19952.1 - 0.83 9.7 6.0 1 9.4 0.5 3.2 1 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain SLATT_5 PF18160.1 GAX19952.1 - 3 7.1 7.0 0.94 8.8 3.4 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 LOH1CR12 PF10158.9 GAX19952.1 - 6.1 6.9 12.5 2.9 7.9 5.9 3.0 2 1 0 3 3 3 0 Tumour suppressor protein DUF1993 PF09351.10 GAX19952.1 - 7.6 6.6 7.5 5.2 7.2 4.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) ABC_tran PF00005.27 GAX19953.1 - 6.8e-43 146.5 0.0 1.2e-21 77.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 GAX19953.1 - 5.9e-40 136.9 59.3 3.3e-28 98.5 21.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter AAA_29 PF13555.6 GAX19953.1 - 1.5e-08 34.2 0.2 0.0021 17.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX19953.1 - 1.7e-07 32.0 0.1 0.0019 18.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAX19953.1 - 3.4e-07 30.8 0.0 0.01 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAX19953.1 - 4.9e-06 26.6 0.0 0.96 9.2 0.0 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAX19953.1 - 4.8e-05 23.7 0.0 0.23 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAX19953.1 - 5e-05 23.3 0.1 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 GAX19953.1 - 6e-05 23.1 0.0 0.0059 16.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 GAX19953.1 - 0.00076 19.4 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 GAX19953.1 - 0.0012 18.6 0.2 1.2 8.8 0.0 2.5 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 GAX19953.1 - 0.0013 18.4 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 GAX19953.1 - 0.0019 17.6 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA PF00004.29 GAX19953.1 - 0.002 18.6 0.0 1.3 9.5 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 GAX19953.1 - 0.0022 17.9 0.7 0.23 11.4 0.0 2.9 4 0 0 4 4 2 1 NTPase DLIC PF05783.11 GAX19953.1 - 0.0035 16.2 0.2 0.09 11.6 0.0 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) TsaE PF02367.17 GAX19953.1 - 0.0052 16.8 0.3 0.85 9.6 0.1 2.9 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAX19953.1 - 0.0093 16.1 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX19953.1 - 0.0098 16.4 0.0 4.8 7.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 GAX19953.1 - 0.018 15.0 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 GAX19953.1 - 0.019 14.6 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 GAX19953.1 - 0.02 15.2 0.1 2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX19953.1 - 0.026 14.3 0.4 8.6 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAX19953.1 - 0.064 13.3 0.2 7.8 6.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 GAX19953.1 - 0.076 12.3 0.1 8.4 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 GAX19953.1 - 0.077 12.3 0.3 4.5 6.6 0.1 2.6 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 GAX19953.1 - 0.091 13.0 0.1 13 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAX19953.1 - 0.12 11.7 0.4 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 GAX19953.1 - 0.12 12.2 0.1 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 GAX19953.1 - 0.14 11.9 0.7 6 6.6 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 GAX19953.1 - 0.18 11.8 0.3 10 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 GAX19953.1 - 0.2 11.3 0.3 19 4.9 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain V_ATPase_I PF01496.19 GAX19954.1 - 6.8e-270 897.5 0.1 1.8e-205 684.5 0.0 2.3 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF1151 PF06625.11 GAX19954.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DR2241 PF18069.1 GAX19954.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 DR2241 stabilising domain AGTRAP PF06396.11 GAX19955.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) RRM_1 PF00076.22 GAX19956.1 - 0.084 12.7 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S1-P1_nuclease PF02265.16 GAX19957.1 - 3.8e-60 203.8 0.0 5.7e-60 203.3 0.0 1.3 1 1 0 1 1 1 1 S1/P1 Nuclease Stc1 PF12898.7 GAX19958.1 - 3.8e-05 24.1 1.7 9.8e-05 22.8 1.7 1.7 1 0 0 1 1 1 1 Stc1 domain TCP PF03634.13 GAX19958.1 - 3 8.4 18.5 0.48 11.0 8.1 2.5 2 0 0 2 2 2 0 TCP family transcription factor TFIIS_M PF07500.14 GAX19959.1 - 0.051 14.0 1.0 0.051 14.0 1.0 2.4 1 1 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain LCM PF04072.14 GAX19960.1 - 6.6e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Lipase_2 PF01674.18 GAX19960.1 - 0.023 14.2 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Lipase (class 2) Chloroa_b-bind PF00504.21 GAX19964.1 - 3.3e-25 89.5 1.1 4.5e-25 89.0 1.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Rit1_C PF17184.4 GAX19965.1 - 2.2e-69 233.9 0.3 2.8e-69 233.6 0.3 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain DUF4519 PF15012.6 GAX19965.1 - 0.23 11.7 0.8 0.5 10.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) FA_desaturase PF00487.24 GAX19967.1 - 1.5e-11 44.6 24.5 2.7e-11 43.8 24.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Methyltransf_31 PF13847.6 GAX19968.1 - 0.028 14.2 0.0 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 GAX19968.1 - 0.15 11.5 0.0 1 8.8 0.0 2.3 1 1 0 1 1 1 0 Putative methyltransferase zf-MYND PF01753.18 GAX19969.1 - 6e-09 35.8 15.3 6e-09 35.8 15.3 3.4 3 1 0 3 3 1 1 MYND finger zf-C3HC4_3 PF13920.6 GAX19969.1 - 5.8e-07 29.3 5.4 5.8e-07 29.3 5.4 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX19969.1 - 1.3e-06 28.7 8.6 1.3e-06 28.7 8.6 2.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAX19969.1 - 5.9e-06 26.1 8.7 5.9e-06 26.1 8.7 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX19969.1 - 0.00027 20.8 8.0 0.00027 20.8 8.0 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX19969.1 - 0.0006 19.8 6.9 0.0006 19.8 6.9 2.2 2 0 0 2 2 1 1 RING-type zinc-finger TPR_2 PF07719.17 GAX19969.1 - 0.00078 19.4 1.1 0.41 10.9 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX19969.1 - 0.0011 19.6 0.5 1.8 9.6 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_11 PF17123.5 GAX19969.1 - 0.0021 17.8 1.9 0.17 11.7 3.8 2.7 1 1 1 2 2 2 1 RING-like zinc finger TPR_12 PF13424.6 GAX19969.1 - 0.0036 17.6 0.8 14 6.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 GAX19969.1 - 0.0039 17.5 8.8 0.0039 17.5 8.8 3.1 3 1 1 4 4 2 1 zf-MYND-like zinc finger, mRNA-binding TPR_19 PF14559.6 GAX19969.1 - 0.0085 16.6 0.3 1.5 9.4 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GAX19969.1 - 0.0087 15.9 5.2 0.0087 15.9 5.2 2.6 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 TPR_1 PF00515.28 GAX19969.1 - 0.011 15.5 0.6 17 5.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 GAX19969.1 - 0.016 15.0 12.0 0.016 15.0 12.0 3.2 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) TPR_10 PF13374.6 GAX19969.1 - 0.018 14.9 1.3 1.5 8.8 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat N2227 PF07942.12 GAX19969.1 - 0.031 13.5 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Peptidase_C6 PF00851.18 GAX19969.1 - 0.037 12.9 0.2 0.054 12.4 0.2 1.2 1 0 0 1 1 1 0 Helper component proteinase TPR_9 PF13371.6 GAX19969.1 - 0.15 12.2 0.2 6.2 7.0 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX19969.1 - 2.3 8.7 6.5 33 5.1 0.2 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat FA_desaturase PF00487.24 GAX19970.1 - 1.6e-10 41.2 12.1 2.7e-10 40.5 12.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase V_ATPase_I PF01496.19 GAX19971.1 - 8.3e-271 900.5 2.6 7.6e-206 685.7 0.0 2.3 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family FlxA PF14282.6 GAX19971.1 - 0.16 12.0 0.6 0.27 11.2 0.6 1.3 1 0 0 1 1 1 0 FlxA-like protein UPF0176_N PF17773.1 GAX19972.1 - 7.2e-12 45.5 0.0 1.9e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAX19972.1 - 2.5e-10 40.5 9.4 2.5e-10 40.5 9.4 2.4 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 GAX19972.1 - 1.9e-08 34.7 0.0 4.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain MIB_HERC2 PF06701.13 GAX19972.1 - 0.032 14.5 0.7 0.093 13.0 0.3 2.0 2 0 0 2 2 2 0 Mib_herc2 GRIM-19 PF06212.12 GAX19973.1 - 1.1e-31 109.6 0.1 1.3e-31 109.3 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein TruD PF01142.18 GAX19974.1 - 1.4e-60 205.3 0.0 2.5e-57 194.6 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) PDT PF00800.18 GAX19976.1 - 2.5e-51 174.1 0.0 4.7e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 Prephenate dehydratase F420_oxidored PF03807.17 GAX19976.1 - 6e-12 46.0 0.0 1.7e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 GAX19976.1 - 6.7e-12 45.0 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 GAX19976.1 - 4.7e-06 26.1 0.0 9.7e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAX19976.1 - 4.4e-05 23.7 0.0 8.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 GAX19976.1 - 0.0017 18.6 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 GAX19976.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 GAX19976.1 - 0.018 14.9 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.16 GAX19976.1 - 0.036 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 GAX19976.1 - 0.086 13.7 0.0 1.1 10.1 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N PF00107.26 GAX19976.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Metallophos_2 PF12850.7 GAX19977.1 - 3.8e-09 37.0 1.0 0.00027 21.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GAX19977.1 - 3.1e-08 34.4 4.2 2.1e-07 31.7 4.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MbeB_N PF04837.12 GAX19979.1 - 0.17 12.2 5.1 0.53 10.6 0.0 3.1 2 0 0 2 2 2 0 MbeB-like, N-term conserved region CdiI_N PF18228.1 GAX19980.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 CdiI N-terminal domain 2-Hacid_dh_C PF02826.19 GAX19982.1 - 7.2e-28 97.1 0.1 1.5e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX19982.1 - 2.1e-18 66.3 0.1 3.4e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAX19982.1 - 4.4e-07 30.2 0.0 1.3e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 GAX19982.1 - 5.2e-05 22.9 0.1 9.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 GAX19982.1 - 0.00033 20.0 0.6 0.00088 18.6 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ACT_4 PF13291.6 GAX19982.1 - 0.0093 16.5 0.4 0.02 15.5 0.4 1.6 1 0 0 1 1 1 1 ACT domain F420_oxidored PF03807.17 GAX19982.1 - 0.02 15.5 0.1 0.059 14.0 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 GAX19982.1 - 0.037 13.9 0.2 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 GAX19982.1 - 0.073 13.1 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.21 GAX19982.1 - 0.084 12.6 1.2 0.22 11.2 0.1 2.1 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 GAX19983.1 - 2.5e-29 101.9 0.0 4.3e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX19983.1 - 1.4e-14 53.9 0.0 2.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 GAX19983.1 - 0.00037 20.2 0.1 0.00085 19.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 GAX19983.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_4 PF13291.6 GAX19983.1 - 0.024 15.2 0.2 0.052 14.1 0.2 1.5 1 0 0 1 1 1 0 ACT domain NUC153 PF08159.12 GAX19984.1 - 1.4e-10 40.8 4.0 2.8e-10 39.8 4.0 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 GAX19984.1 - 1.1e-05 26.1 0.6 0.07 14.0 0.2 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat SAM_adeno_trans PF01887.16 GAX19984.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Adaptin_N PF01602.20 GAX19985.1 - 8.6e-96 321.6 0.3 1.2e-95 321.1 0.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 GAX19985.1 - 5.6e-17 61.9 0.0 1.4e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 GAX19985.1 - 4.4e-09 36.6 1.3 3.3e-07 30.5 0.1 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Alpha_adaptinC2 PF02883.20 GAX19985.1 - 1.4e-08 35.0 0.0 3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.22 GAX19985.1 - 0.063 13.6 2.1 10 6.7 0.1 3.6 2 0 0 2 2 2 0 HEAT repeat EGF_2 PF07974.13 GAX19986.1 - 0.01 16.2 1.8 0.01 16.2 1.8 10.5 9 2 0 9 9 9 0 EGF-like domain GalKase_gal_bdg PF10509.9 GAX19986.1 - 0.05 13.2 0.3 2 8.0 0.1 3.3 3 0 0 3 3 3 0 Galactokinase galactose-binding signature EGF PF00008.27 GAX19987.1 - 0.00096 19.4 53.3 0.1 12.9 0.7 5.6 4 2 0 4 4 4 4 EGF-like domain EGF_2 PF07974.13 GAX19987.1 - 0.013 15.8 52.9 0.24 11.8 13.5 5.3 4 2 0 4 4 4 0 EGF-like domain hEGF PF12661.7 GAX19987.1 - 9.4 7.0 42.8 5.2 7.9 4.4 6.9 5 2 0 5 5 5 0 Human growth factor-like EGF DegT_DnrJ_EryC1 PF01041.17 GAX19988.1 - 1.6e-48 165.9 0.1 2e-48 165.6 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 GAX19988.1 - 6.2e-14 51.9 0.2 1.3e-13 50.8 0.2 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX19988.1 - 9.1e-05 21.2 0.0 0.00027 19.6 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAX19988.1 - 0.0022 17.0 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.19 GAX19988.1 - 0.0041 15.8 0.3 0.0053 15.4 0.3 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF4806 PF16064.5 GAX19988.1 - 0.08 13.2 0.2 8.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) TPR_17 PF13431.6 GAX19989.1 - 0.0068 16.7 3.4 0.36 11.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat RuBisCO_small PF00101.20 GAX19989.1 - 0.016 15.2 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain TPR_19 PF14559.6 GAX19989.1 - 0.016 15.7 1.2 0.038 14.5 1.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX19989.1 - 0.023 14.4 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 GAX19989.1 - 0.078 13.1 0.3 0.078 13.1 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX19989.1 - 0.081 13.2 0.6 0.26 11.6 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Porin_OmpG PF09381.10 GAX19989.1 - 0.16 11.7 0.2 0.25 11.1 0.2 1.1 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) DnaJ_C PF01556.18 GAX19990.1 - 1.1e-36 126.1 0.9 1.6e-36 125.6 0.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX19990.1 - 4.2e-27 94.0 2.2 7.9e-27 93.2 2.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2997 PF11211.8 GAX19991.1 - 3.9e-19 68.2 0.1 6.1e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2997) Synaptobrevin PF00957.21 GAX19992.1 - 1e-16 60.5 0.3 1.9e-16 59.6 0.3 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAX19992.1 - 1.3e-11 44.4 0.0 2.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain FAM163 PF15069.6 GAX19992.1 - 0.032 14.7 0.2 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 FAM163 family DUF2721 PF11026.8 GAX19992.1 - 0.048 13.6 0.5 0.082 12.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Pro-kuma_activ PF09286.11 GAX19992.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain Cytochrom_NNT PF03264.14 GAX19992.1 - 0.14 11.8 0.2 0.14 11.8 0.2 2.4 1 1 2 3 3 3 0 NapC/NirT cytochrome c family, N-terminal region CdiI_4 PF18624.1 GAX19992.1 - 0.51 10.8 3.3 0.28 11.7 0.5 2.0 2 1 0 2 2 2 0 CDI immunity protein Ly49 PF08391.10 GAX19992.1 - 0.72 10.2 3.1 25 5.3 0.9 3.0 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region adh_short PF00106.25 GAX19993.1 - 5.4e-23 81.5 0.0 1e-19 70.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX19993.1 - 7.2e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX19993.1 - 0.00065 19.7 0.5 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 GAX19993.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Vps5 PF09325.10 GAX19994.1 - 1.1e-32 113.5 4.2 1.5e-32 113.0 4.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 GAX19994.1 - 5.4e-20 71.5 0.0 1.2e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR PF03114.18 GAX19994.1 - 2.2e-11 43.9 3.9 3e-11 43.4 3.9 1.2 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.9 GAX19994.1 - 1.6e-05 24.5 3.1 0.0033 16.9 3.1 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Pil1 PF13805.6 GAX19994.1 - 0.0017 17.9 0.9 0.0026 17.3 0.9 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 EGF_2 PF07974.13 GAX19995.1 - 5.6e-17 61.8 68.3 0.00076 19.8 2.4 8.7 7 3 0 7 7 7 6 EGF-like domain EGF PF00008.27 GAX19995.1 - 1.8e-11 44.1 84.5 0.0061 16.8 5.0 9.7 8 1 0 8 8 8 7 EGF-like domain Pkinase PF00069.25 GAX19996.1 - 1.7e-73 247.3 0.0 1.9e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX19996.1 - 6.3e-46 156.8 0.0 7.7e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX19996.1 - 0.0027 16.5 0.0 0.0035 16.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAX19996.1 - 0.0098 15.2 0.0 0.064 12.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DSPc PF00782.20 GAX19997.1 - 6.6e-09 35.7 0.0 9.4e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX19997.1 - 0.00014 21.5 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAX19997.1 - 0.0016 18.6 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate SepRS_C PF18006.1 GAX19997.1 - 3 8.0 4.1 8.9 6.5 0.4 2.7 3 0 0 3 3 3 0 O-phosphoseryl-tRNA synthetase C-terminal domain HAT_KAT11 PF08214.11 GAX19998.1 - 2.6e-28 99.3 0.0 2.6e-28 99.3 0.0 2.7 3 0 0 3 3 3 1 Histone acetylation protein zf-TAZ PF02135.16 GAX19998.1 - 3.1e-19 69.2 43.5 1.1e-11 45.0 19.6 5.2 6 0 0 6 6 6 2 TAZ zinc finger Bromodomain PF00439.25 GAX19998.1 - 8.8e-18 64.2 0.0 3.2e-17 62.4 0.0 2.1 1 0 0 1 1 1 1 Bromodomain KIX_2 PF16987.5 GAX19998.1 - 3.2e-05 23.8 0.0 0.0002 21.3 0.0 2.5 1 0 0 1 1 1 1 KIX domain PHD PF00628.29 GAX19998.1 - 6.2e-05 22.8 4.5 6.2e-05 22.8 4.5 4.2 4 0 0 4 4 4 1 PHD-finger ZZ PF00569.17 GAX19998.1 - 0.00034 20.4 7.3 0.00034 20.4 7.3 3.0 5 0 0 5 5 5 1 Zinc finger, ZZ type DUF902 PF06001.13 GAX19998.1 - 0.017 15.6 0.7 0.042 14.3 0.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) PUF PF00806.19 GAX19999.1 - 0.00011 21.6 0.2 0.22 11.3 0.0 4.6 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat TPR_1 PF00515.28 GAX20000.1 - 1.3e-15 56.4 2.0 1.2e-05 24.9 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX20000.1 - 2.2e-14 52.3 10.9 0.009 16.1 0.0 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX20000.1 - 4.1e-11 42.7 4.1 2.6 9.1 0.0 8.0 5 3 3 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX20000.1 - 2.8e-10 40.3 8.2 0.18 12.1 0.3 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAX20000.1 - 8e-10 39.1 3.1 0.036 14.6 0.0 5.7 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20000.1 - 1.4e-08 34.3 7.1 0.76 10.1 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX20000.1 - 1.7e-07 31.7 0.2 6 7.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX20000.1 - 9.2e-07 28.4 2.5 0.17 11.6 0.0 5.7 7 0 0 7 7 7 1 TPR repeat TPR_12 PF13424.6 GAX20000.1 - 2.3e-06 27.8 10.3 0.0074 16.5 0.1 6.1 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX20000.1 - 8.1e-06 25.4 3.5 0.00071 19.0 2.3 2.8 2 2 0 2 2 2 1 MalT-like TPR region zf-RING_2 PF13639.6 GAX20000.1 - 1.3e-05 25.4 12.1 3e-05 24.3 12.1 1.7 1 0 0 1 1 1 1 Ring finger domain TPR_17 PF13431.6 GAX20000.1 - 0.00024 21.3 0.0 5.7 7.6 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 GAX20000.1 - 0.0013 18.7 5.1 0.0013 18.7 5.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX20000.1 - 0.0017 18.2 11.4 0.0035 17.2 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX20000.1 - 0.0029 17.4 11.0 0.0066 16.3 11.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX20000.1 - 0.0029 17.4 8.9 0.0059 16.4 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_9 PF13371.6 GAX20000.1 - 0.0038 17.3 0.3 0.36 11.0 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GAX20000.1 - 0.0054 16.6 10.0 0.012 15.4 10.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAX20000.1 - 0.007 16.3 9.9 0.014 15.3 9.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF1771 PF08590.10 GAX20000.1 - 0.025 15.0 6.5 2.4 8.6 0.1 3.5 4 0 0 4 4 2 0 Domain of unknown function (DUF1771) zf-C3HC4_4 PF15227.6 GAX20000.1 - 0.053 13.7 8.9 0.14 12.4 8.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_10 PF13374.6 GAX20000.1 - 0.053 13.4 7.5 8.6 6.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 GAX20000.1 - 0.059 13.7 8.9 0.15 12.3 8.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF3856 PF12968.7 GAX20000.1 - 0.1 12.7 3.8 30 4.7 0.0 4.3 3 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 GAX20000.1 - 0.15 12.1 3.5 0.79 9.8 0.0 3.6 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain zf-ANAPC11 PF12861.7 GAX20000.1 - 1 9.4 4.4 2.2 8.4 4.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger BTAD PF03704.17 GAX20000.1 - 2.4 8.6 14.9 5.1 7.5 0.2 4.5 2 1 3 5 5 4 0 Bacterial transcriptional activator domain YfdX PF10938.8 GAX20000.1 - 5 7.1 9.3 15 5.5 0.1 4.3 5 1 0 5 5 3 0 YfdX protein WD40 PF00400.32 GAX20004.1 - 1.2e-24 86.1 0.3 6.6e-05 23.6 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX20004.1 - 2e-12 47.2 0.0 0.00091 19.5 0.0 4.4 3 2 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX20004.1 - 0.0015 18.4 0.0 6.5 6.6 0.0 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 GAX20004.1 - 0.019 14.6 0.0 0.067 12.8 0.0 1.8 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Cnd3 PF12719.7 GAX20005.1 - 1.6e-27 96.5 0.0 1.6e-27 96.5 0.0 3.2 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GAX20005.1 - 4.7e-08 33.3 3.3 0.039 14.3 0.1 5.3 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.22 GAX20005.1 - 0.00094 19.2 5.0 6.8 7.2 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat GatB_Yqey PF02637.18 GAX20005.1 - 0.11 12.4 0.6 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 GatB domain HpcH_HpaI PF03328.14 GAX20006.1 - 6e-29 100.8 0.0 7.5e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DNA_gyraseB PF00204.25 GAX20007.1 - 3.3e-47 160.2 0.0 6.1e-47 159.3 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 GAX20007.1 - 7.9e-29 99.6 0.1 1.9e-28 98.4 0.1 1.7 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.22 GAX20007.1 - 4.5e-20 71.8 0.0 1e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.26 GAX20007.1 - 4.1e-17 62.7 0.1 1.9e-16 60.5 0.1 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX20007.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Se-cys_synth_N PF12390.8 GAX20007.1 - 0.072 13.3 0.3 0.26 11.5 0.3 2.0 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Pyr_redox_2 PF07992.14 GAX20008.1 - 1.5e-12 47.4 0.1 1.1e-10 41.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX20008.1 - 9.4e-06 26.1 0.0 0.22 12.1 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX20008.1 - 0.00065 19.7 0.0 0.0018 18.3 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GAX20008.1 - 0.0014 18.0 0.1 0.0097 15.2 0.5 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 GAX20008.1 - 0.003 17.8 0.0 0.003 17.8 0.0 2.4 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX20008.1 - 0.0031 16.8 0.1 0.38 10.0 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Trp_halogenase PF04820.14 GAX20008.1 - 0.019 13.8 0.1 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 GAX20008.1 - 0.051 12.8 0.1 0.95 8.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 GAX20008.1 - 0.12 11.7 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 GAX20008.1 - 0.15 12.1 0.0 9 6.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RPN7 PF10602.9 GAX20009.1 - 4e-41 140.6 0.8 6.4e-41 140.0 0.8 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAX20009.1 - 1.3e-13 51.3 0.0 3.2e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain Barstar PF01337.18 GAX20009.1 - 0.0073 16.3 0.0 0.62 10.1 0.0 2.8 2 1 0 2 2 2 1 Barstar (barnase inhibitor) DUF3209 PF11483.8 GAX20009.1 - 0.061 13.8 2.6 0.27 11.7 2.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3209) Peptidase_C14 PF00656.22 GAX20012.1 - 2.9e-22 79.8 0.1 5.6e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Caspase domain NMT PF01233.19 GAX20013.1 - 2.2e-73 245.4 0.0 1.1e-72 243.1 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 GAX20013.1 - 3.8e-73 245.5 0.0 5.2e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 GAX20013.1 - 0.0033 17.6 0.0 0.0063 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 GAX20013.1 - 0.004 17.2 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF760 PF05542.11 GAX20014.1 - 3e-27 94.8 0.0 3.7e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF760) EF-hand_7 PF13499.6 GAX20014.1 - 2.2e-10 40.9 4.3 5.7e-10 39.5 4.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX20014.1 - 2.9e-10 38.9 9.4 4.8e-05 22.6 0.6 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX20014.1 - 7.6e-10 37.9 7.1 8.5e-05 22.2 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX20014.1 - 5e-09 35.3 7.7 0.00067 19.0 2.7 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAX20014.1 - 3.8e-08 33.0 4.4 0.00077 19.3 1.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAX20014.1 - 0.18 12.1 0.2 0.39 11.1 0.2 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ATE_C PF04377.15 GAX20015.1 - 3e-45 154.1 0.3 1.2e-44 152.1 0.3 1.8 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Ras PF00071.22 GAX20016.1 - 5.7e-14 52.0 0.0 6.5e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 GAX20016.1 - 0.00058 19.4 0.0 0.0007 19.2 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B adh_short_C2 PF13561.6 GAX20016.1 - 0.072 12.6 0.0 0.087 12.4 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TAF6_C PF07571.13 GAX20017.1 - 0.16 12.3 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain zf-C2H2_8 PF15909.5 GAX20018.1 - 0.06 13.7 0.2 0.2 12.0 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon Acetyltransf_1 PF00583.25 GAX20020.1 - 2.7e-10 40.5 0.0 4.5e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAX20020.1 - 1.3e-05 25.1 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAX20020.1 - 2e-05 24.5 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX20020.1 - 6.5e-05 23.3 0.0 0.0002 21.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX20020.1 - 0.0018 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 GAX20020.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Pirin PF02678.16 GAX20021.1 - 1e-29 102.7 0.3 1.7e-29 101.9 0.3 1.3 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 GAX20021.1 - 7.7e-14 51.6 0.1 1.7e-13 50.5 0.0 1.6 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 GAX20021.1 - 5.4e-07 29.2 0.1 1.3e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Cupin domain Pirin_C PF05726.13 GAX20021.1 - 0.0076 16.6 0.1 0.1 13.0 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain MBOAT_2 PF13813.6 GAX20023.1 - 1.7e-11 44.2 0.5 4.2e-11 43.0 0.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PCI PF01399.27 GAX20024.1 - 3.5e-14 53.2 0.0 7.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 GAX20024.1 - 4e-08 32.8 3.8 6.7e-08 32.1 1.6 2.3 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix Cation_efflux PF01545.21 GAX20025.1 - 3e-07 30.4 10.4 4.1e-07 29.9 10.4 1.2 1 0 0 1 1 1 1 Cation efflux family UbiA PF01040.18 GAX20025.1 - 0.0018 17.6 9.7 0.0061 15.9 3.1 2.9 2 1 1 3 3 3 2 UbiA prenyltransferase family Tmemb_14 PF03647.13 GAX20025.1 - 0.0068 17.1 2.9 1.7 9.4 0.8 3.1 2 1 0 2 2 2 1 Transmembrane proteins 14C DUF872 PF05915.12 GAX20025.1 - 0.014 15.5 6.3 2.5 8.3 0.5 3.0 1 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) TssN PF17555.2 GAX20025.1 - 0.026 13.9 1.3 0.044 13.2 1.3 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN NCE101 PF11654.8 GAX20025.1 - 0.055 13.2 0.1 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 DPM3 PF08285.11 GAX20025.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.6 3 1 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TauE PF01925.19 GAX20025.1 - 0.14 11.8 11.4 0.033 13.8 5.2 2.2 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF2370 PF10176.9 GAX20025.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) TctB PF07331.11 GAX20025.1 - 0.24 11.7 10.0 0.41 10.9 9.6 1.7 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF202 PF02656.15 GAX20025.1 - 0.32 11.5 14.4 6 7.4 1.2 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4203 PF13886.6 GAX20025.1 - 0.35 10.5 10.8 0.14 11.8 6.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4203) Polysacc_synt_C PF14667.6 GAX20025.1 - 1.1 9.3 10.0 0.32 11.0 4.3 2.5 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain YfhO PF09586.10 GAX20025.1 - 1.2 7.2 3.9 1.6 6.8 3.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO YiaAB PF05360.14 GAX20025.1 - 2.3 8.5 0.0 2.3 8.5 0.0 4.0 5 0 0 5 5 4 0 yiaA/B two helix domain DUF1761 PF08570.10 GAX20025.1 - 2.8 8.2 10.3 0.78 10.0 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) DUF4212 PF13937.6 GAX20025.1 - 4.6 7.7 10.8 1.8 9.0 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4212) Nodulin-like PF06813.13 GAX20027.1 - 1.9e-13 50.5 11.0 5.1e-13 49.1 11.0 1.7 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 GAX20027.1 - 1.5e-05 24.1 8.0 1.5e-05 24.1 8.0 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily Sulfotransfer_2 PF03567.14 GAX20028.1 - 0.053 13.4 2.8 0.13 12.1 0.8 2.0 1 1 1 2 2 2 0 Sulfotransferase family DUF1681 PF07933.14 GAX20030.1 - 2.1e-28 98.9 0.0 2.6e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Exo84_C PF16528.5 GAX20031.1 - 1.3e-08 34.9 1.0 4e-05 23.5 1.1 3.3 2 1 0 2 2 2 1 Exocyst component 84 C-terminal COG2 PF06148.11 GAX20031.1 - 0.00028 21.0 0.8 0.0088 16.1 0.0 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 GAX20031.1 - 0.00051 20.1 0.6 0.008 16.2 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 PH PF00169.29 GAX20031.1 - 0.0022 18.5 0.0 0.0049 17.4 0.0 1.6 1 0 0 1 1 1 1 PH domain SGTA_dimer PF16546.5 GAX20031.1 - 0.029 14.1 0.1 0.081 12.7 0.1 1.7 1 0 0 1 1 1 0 Homodimerisation domain of SGTA VirD1 PF07328.11 GAX20032.1 - 0.007 16.3 0.1 1.3 9.0 0.0 2.8 2 1 1 3 3 3 1 T-DNA border endonuclease VirD1 DivIVA PF05103.13 GAX20032.1 - 0.013 15.6 24.8 0.091 12.8 1.1 4.7 2 1 0 4 4 4 0 DivIVA protein CorA PF01544.18 GAX20032.1 - 0.015 14.6 11.4 0.76 9.0 10.6 2.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein LtuB PF17455.2 GAX20032.1 - 0.02 15.5 5.6 1.9 9.2 1.0 3.1 1 1 1 2 2 2 0 Late transcription unit B Fzo_mitofusin PF04799.13 GAX20032.1 - 0.13 11.8 20.4 0.022 14.3 2.6 3.6 3 0 0 3 3 3 0 fzo-like conserved region DUF1024 PF06260.12 GAX20032.1 - 0.13 12.5 3.9 10 6.5 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1024) Strep_SA_rep PF06696.11 GAX20032.1 - 0.15 12.1 3.9 3.3 7.8 0.2 3.4 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Vps4_C PF09336.10 GAX20032.1 - 0.23 11.5 0.8 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DASH_Duo1 PF08651.10 GAX20032.1 - 0.38 10.6 14.2 0.68 9.7 0.7 4.1 4 1 0 4 4 4 0 DASH complex subunit Duo1 PikAIV_N PF18605.1 GAX20032.1 - 0.55 9.9 15.9 1.6 8.3 1.4 4.2 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain OmpH PF03938.14 GAX20032.1 - 1.2 9.5 27.0 38 4.6 2.7 4.3 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 GAX20032.1 - 2.6 8.3 16.8 0.24 11.7 2.4 4.0 3 2 0 3 3 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 GAX20032.1 - 6 6.2 41.5 1.1 8.5 0.4 4.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 GAX20032.1 - 6.9 7.4 32.9 0.78 10.4 6.1 4.3 2 1 2 4 4 4 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 GAX20032.1 - 8 6.7 41.7 1.5 9.1 16.2 4.1 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.12 GAX20032.1 - 8.3 7.0 12.3 0.91 10.0 1.5 3.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 GAX20033.1 - 0.00029 20.9 13.0 0.00029 20.9 13.0 4.5 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.11 GAX20033.1 - 0.00038 19.5 41.7 0.027 13.4 15.6 2.3 2 0 0 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like Stap_Strp_toxin PF01123.20 GAX20033.1 - 0.074 13.9 0.4 0.91 10.4 0.0 2.8 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain HTH_13 PF11972.8 GAX20033.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain DUF4407 PF14362.6 GAX20033.1 - 0.78 9.0 23.7 1.4 8.2 6.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SfsA PF03749.13 GAX20036.1 - 9e-24 83.9 0.1 5.8e-15 55.4 0.1 2.3 2 0 0 2 2 2 2 Sugar fermentation stimulation protein RE domain SpoU_methylase PF00588.19 GAX20037.1 - 1.4e-26 93.3 0.2 4.1e-20 72.4 0.0 2.7 3 0 0 3 3 3 2 SpoU rRNA Methylase family MCM PF00493.23 GAX20038.1 - 3.7e-95 317.3 0.0 6.1e-95 316.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX20038.1 - 1.1e-32 112.5 1.4 2.4e-32 111.4 0.4 2.1 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 GAX20038.1 - 1.4e-27 95.9 0.2 4.9e-27 94.2 0.2 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 GAX20038.1 - 8.7e-08 32.7 1.5 2.8e-06 27.9 1.5 2.5 1 1 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 GAX20038.1 - 0.00039 20.3 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAX20038.1 - 0.0004 19.8 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX20038.1 - 0.0089 16.0 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ArsA_ATPase PF02374.15 GAX20039.1 - 6.4e-117 390.1 0.0 1.1e-58 198.8 0.0 2.5 2 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 GAX20039.1 - 3.9e-22 78.7 0.0 1.4e-11 44.6 0.0 3.3 2 2 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX20039.1 - 9.1e-20 71.3 4.8 4.5e-10 39.7 0.1 4.6 3 2 0 3 3 3 2 AAA domain ParA PF10609.9 GAX20039.1 - 4.7e-14 52.4 9.1 7.2e-07 28.9 0.7 4.4 5 0 0 5 5 5 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 GAX20039.1 - 1.3e-08 34.6 1.5 0.00018 21.1 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 GAX20039.1 - 1.5e-07 31.2 1.9 0.025 14.2 0.1 3.9 4 0 0 4 4 4 2 AAA domain MeaB PF03308.16 GAX20039.1 - 3.2e-07 29.6 1.9 0.00015 20.8 0.0 3.0 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 GAX20039.1 - 5.5e-07 29.2 0.1 0.078 12.4 0.0 3.3 3 0 0 3 3 3 2 PhoH-like protein AAA_16 PF13191.6 GAX20039.1 - 5.6e-07 30.1 0.6 0.0047 17.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 GAX20039.1 - 7.4e-07 28.6 1.9 0.0011 18.3 0.1 2.7 2 1 1 3 3 3 2 Zeta toxin CBP_BcsQ PF06564.12 GAX20039.1 - 3.4e-06 26.7 0.5 0.074 12.5 0.0 2.6 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 GAX20039.1 - 6.7e-06 25.9 7.5 0.00078 19.1 0.2 3.9 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain AAA_18 PF13238.6 GAX20039.1 - 5e-05 23.9 1.3 0.064 13.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain VirC1 PF07015.11 GAX20039.1 - 0.00014 21.3 0.7 0.0033 16.7 0.2 2.6 2 0 0 2 2 2 1 VirC1 protein IstB_IS21 PF01695.17 GAX20039.1 - 0.00029 20.6 0.1 0.83 9.4 0.1 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein MipZ PF09140.11 GAX20039.1 - 0.00056 19.3 5.5 0.0012 18.2 0.4 3.1 3 0 0 3 3 3 1 ATPase MipZ AAA_24 PF13479.6 GAX20039.1 - 0.00057 19.7 0.2 0.33 10.6 0.0 2.7 2 2 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAX20039.1 - 0.0011 18.2 0.3 0.68 9.1 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DnaB_C PF03796.15 GAX20039.1 - 0.0012 18.2 0.5 1.9 7.7 0.0 2.8 3 0 0 3 3 3 2 DnaB-like helicase C terminal domain DUF1611 PF07755.11 GAX20039.1 - 0.003 16.9 0.8 0.0092 15.3 0.1 2.1 3 0 0 3 3 2 1 Domain of unknown function (DUF1611_C) P-loop domain AAA_30 PF13604.6 GAX20039.1 - 0.0031 17.3 3.3 0.26 11.0 0.2 3.4 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 GAX20039.1 - 0.0032 17.9 0.2 3.4 8.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 GAX20039.1 - 0.0042 16.6 0.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 GAX20039.1 - 0.0044 16.9 0.3 4.9 7.0 0.1 3.0 3 0 0 3 3 3 0 RsgA GTPase ATPase PF06745.13 GAX20039.1 - 0.0056 16.1 1.0 2.1 7.6 0.0 3.4 4 0 0 4 4 3 1 KaiC CLP1_P PF16575.5 GAX20039.1 - 0.0077 16.1 0.9 0.83 9.4 0.0 3.6 4 0 0 4 4 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop LpxK PF02606.14 GAX20039.1 - 0.02 14.0 1.2 1.1 8.3 0.1 2.9 3 0 0 3 3 3 0 Tetraacyldisaccharide-1-P 4'-kinase PIF1 PF05970.14 GAX20039.1 - 0.021 14.0 0.3 2.1 7.5 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase FtsK_SpoIIIE PF01580.18 GAX20039.1 - 0.024 14.0 0.9 0.17 11.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 GAX20039.1 - 0.037 13.9 1.8 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Mur_ligase_M PF08245.12 GAX20039.1 - 0.06 13.3 0.0 10 6.1 0.1 2.5 2 0 0 2 2 2 0 Mur ligase middle domain AAA PF00004.29 GAX20039.1 - 0.073 13.5 0.4 38 4.7 0.0 3.7 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 GAX20039.1 - 0.086 12.6 2.9 0.38 10.5 0.3 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 GAX20039.1 - 0.11 12.7 0.1 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_26 PF13500.6 GAX20039.1 - 0.14 12.0 2.5 14 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Peptidase_M15 PF01427.17 GAX20039.1 - 0.17 11.6 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase APS_kinase PF01583.20 GAX20039.1 - 0.28 11.1 0.8 29 4.5 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 GAX20039.1 - 0.35 11.1 2.2 4.1 7.6 0.8 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAX20039.1 - 0.42 9.8 2.3 0.94 8.6 0.0 2.4 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) CTP_synth_N PF06418.14 GAX20039.1 - 6.3 6.0 7.0 0.24 10.7 0.3 2.0 3 0 0 3 3 1 0 CTP synthase N-terminus GCD14 PF08704.10 GAX20040.1 - 2.3e-75 253.5 0.1 4.9e-75 252.4 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 GAX20040.1 - 9e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20040.1 - 2.6e-05 24.8 0.0 6.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAX20040.1 - 9.8e-05 23.3 0.0 0.00026 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX20040.1 - 0.0025 18.5 0.0 0.0066 17.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GAX20040.1 - 0.0038 16.6 0.0 0.0077 15.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14_N PF14801.6 GAX20040.1 - 0.0047 16.7 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_11 PF08241.12 GAX20040.1 - 0.011 16.3 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAX20040.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 GAX20040.1 - 0.027 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 GAX20040.1 - 0.04 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family WW PF00397.26 GAX20041.1 - 6e-07 29.4 3.0 1.8e-06 27.9 3.0 1.9 1 0 0 1 1 1 1 WW domain GSHPx PF00255.19 GAX20042.1 - 5.8e-21 74.1 0.6 1.1e-20 73.2 0.2 1.6 1 1 1 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.21 GAX20042.1 - 0.00036 20.5 0.1 0.00064 19.6 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX20042.1 - 0.0027 17.5 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin Methyltrans_RNA PF04452.14 GAX20043.1 - 1.4e-27 96.5 0.0 2e-26 92.8 0.0 2.0 1 1 0 1 1 1 1 RNA methyltransferase APG6 PF04111.12 GAX20043.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Apg6 BARA domain GCV_H PF01597.19 GAX20044.1 - 1.9e-43 147.3 0.1 2.2e-43 147.0 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 GAX20044.1 - 1.9e-05 24.5 0.1 3.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 GAX20044.1 - 0.00017 21.4 0.3 0.00037 20.3 0.2 1.7 1 1 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 GAX20044.1 - 0.021 14.6 0.3 0.042 13.6 0.2 1.5 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 AOC_like PF18678.1 GAX20044.1 - 0.021 14.4 0.0 6.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Allene oxide cyclase barrel like domain CMAS PF02353.20 GAX20044.1 - 0.051 12.9 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase zf-primase PF09329.11 GAX20045.1 - 2.2e-06 27.4 6.1 8.2e-06 25.5 6.1 2.0 1 1 0 1 1 1 1 Primase zinc finger Ribosomal_L25p PF01386.19 GAX20047.1 - 1.6e-10 41.3 0.0 4.2e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 GAX20047.1 - 1.5e-06 28.5 0.0 3.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain HisG PF01634.18 GAX20048.1 - 4.4e-54 182.8 0.3 6e-54 182.3 0.3 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 GAX20048.1 - 1.2e-21 76.6 0.1 2.9e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 GAX20048.1 - 0.0017 18.3 0.3 0.0047 16.9 0.2 1.7 1 1 0 1 1 1 1 NMT1/THI5 like P5CR_dimer PF14748.6 GAX20049.1 - 3e-43 146.3 1.8 5.2e-43 145.5 1.1 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAX20049.1 - 4.7e-13 49.5 1.9 4.7e-13 49.5 1.9 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAX20049.1 - 0.0001 22.5 1.0 0.00019 21.6 1.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 GAX20049.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L13 PF00572.18 GAX20050.1 - 3.8e-06 27.2 0.0 8.4e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 Nup88 PF10168.9 GAX20051.1 - 0.014 13.2 8.8 0.021 12.6 8.8 1.1 1 0 0 1 1 1 0 Nuclear pore component Endonuclea_NS_2 PF13930.6 GAX20051.1 - 0.073 13.2 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease DUF4790 PF16037.5 GAX20052.1 - 0.0042 17.5 0.0 0.0053 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4790) LapA_dom PF06305.11 GAX20052.1 - 0.0066 16.2 0.5 0.0085 15.9 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain BCCT PF02028.17 GAX20052.1 - 0.011 14.2 0.1 0.013 14.0 0.1 1.0 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter Sigma_reg_N PF13800.6 GAX20052.1 - 0.024 14.9 0.1 0.028 14.7 0.1 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Tmemb_9 PF05434.11 GAX20052.1 - 0.062 13.2 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 TMEM9 Metallophos PF00149.28 GAX20053.1 - 5.8e-14 53.1 0.2 9.4e-14 52.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L4 PF00573.22 GAX20054.1 - 1.2e-36 126.2 0.1 2.2e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAX20054.1 - 9e-19 67.3 2.5 2.1e-18 66.1 1.7 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain CEP44 PF15007.6 GAX20055.1 - 0.14 12.4 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Bromodomain PF00439.25 GAX20056.1 - 3.3e-15 55.9 0.0 7.3e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 GAX20056.1 - 0.00018 21.3 9.6 0.00018 21.3 9.6 3.6 2 1 1 3 3 3 1 PHD-finger Peptidase_U49 PF10463.9 GAX20056.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase U49 SNF5 PF04855.12 GAX20056.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 Thioredoxin_8 PF13905.6 GAX20058.1 - 4e-24 84.8 0.0 6.7e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 GAX20058.1 - 3.5e-09 36.6 0.1 4.3e-06 26.7 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 GAX20058.1 - 1.3e-06 28.9 0.0 4.4e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.10 GAX20058.1 - 0.0007 19.3 0.0 0.0034 17.1 0.0 2.0 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAX20058.1 - 0.00088 19.2 0.1 0.0024 17.8 0.0 1.8 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_9 PF14595.6 GAX20058.1 - 0.041 13.7 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin NADH_4Fe-4S PF10589.9 GAX20058.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Thioredoxin_7 PF13899.6 GAX20058.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Methyltransf_10 PF05971.12 GAX20059.1 - 3.2e-33 115.4 0.0 8.1e-33 114.0 0.0 1.7 1 1 0 1 1 1 1 RNA methyltransferase Ras PF00071.22 GAX20060.1 - 1.8e-57 193.5 0.0 2.3e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX20060.1 - 1e-36 125.8 0.1 1.4e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX20060.1 - 2.9e-15 56.2 0.0 3.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAX20060.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX20060.1 - 2.1e-05 24.1 0.0 6e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAX20060.1 - 0.00046 19.7 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX20060.1 - 0.0012 18.9 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX20060.1 - 0.0021 18.0 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 GAX20060.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 GAX20060.1 - 0.19 11.1 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein PGI PF00342.19 GAX20061.1 - 2.5e-142 474.9 0.0 2e-128 429.1 0.0 2.0 1 1 0 2 2 2 2 Phosphoglucose isomerase PGI PF00342.19 GAX20062.1 - 4.5e-238 790.7 0.1 5.1e-238 790.5 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase tRNA-synt_His PF13393.6 GAX20063.1 - 1.2e-43 149.6 0.0 1.7e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 GAX20063.1 - 1.2e-15 57.4 0.0 2.5e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAX20063.1 - 2.5e-07 30.8 0.0 4.7e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 GAX20063.1 - 0.019 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF2999 PF11212.8 GAX20063.1 - 0.12 12.7 0.1 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) Cation_efflux PF01545.21 GAX20064.1 - 1.3e-25 90.3 5.4 1.7e-25 89.9 5.4 1.1 1 0 0 1 1 1 1 Cation efflux family MRG PF05712.13 GAX20065.1 - 2.5e-28 98.8 0.1 8.1e-28 97.1 0.1 1.8 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 GAX20065.1 - 3.7e-05 23.5 0.5 8.3e-05 22.4 0.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF3440 PF11922.8 GAX20065.1 - 0.042 13.5 0.2 0.092 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) PWWP PF00855.17 GAX20065.1 - 0.048 14.1 1.8 0.26 11.7 0.1 2.4 2 0 0 2 2 2 0 PWWP domain SAP PF02037.27 GAX20066.1 - 2.3e-10 39.9 2.4 3.8e-10 39.3 2.4 1.4 1 0 0 1 1 1 1 SAP domain CS PF04969.16 GAX20066.1 - 1.8e-08 35.3 0.4 9.8e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 CS domain Telomere_Sde2_2 PF13297.6 GAX20066.1 - 0.0011 18.5 0.1 0.003 17.2 0.1 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal DIMCO_N PF16844.5 GAX20066.1 - 0.23 11.8 1.0 13 6.2 0.3 2.5 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Tir_receptor_M PF03549.14 GAX20066.1 - 1.9 8.9 5.2 24 5.3 0.3 3.0 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) intimin-binding domain RPN6_N PF18055.1 GAX20067.1 - 2.2e-22 79.6 0.3 2.2e-22 79.6 0.3 2.8 4 0 0 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 GAX20067.1 - 3.7e-22 78.8 0.8 2e-20 73.2 0.9 2.7 2 0 0 2 2 2 1 PCI domain TPR_MalT PF17874.1 GAX20067.1 - 0.0011 18.4 5.8 0.049 13.0 3.2 2.7 2 1 1 3 3 3 2 MalT-like TPR region DDRGK PF09756.9 GAX20067.1 - 0.0011 18.5 0.7 0.0024 17.5 0.7 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_12 PF13424.6 GAX20067.1 - 0.0084 16.4 8.0 0.028 14.7 1.4 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX20067.1 - 0.018 15.6 6.1 5.2 7.6 0.5 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DnaGprimase_HBD PF16730.5 GAX20067.1 - 0.024 14.7 1.7 0.052 13.6 0.4 2.2 2 1 1 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain TPR_2 PF07719.17 GAX20067.1 - 0.046 13.9 4.9 41 4.6 0.1 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat RPN6_C_helix PF18503.1 GAX20067.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Agenet PF05641.12 GAX20068.1 - 3.4e-06 27.4 0.3 1.2e-05 25.7 0.2 2.0 2 0 0 2 2 2 1 Agenet domain DUF3499 PF12005.8 GAX20068.1 - 0.018 15.7 1.1 0.04 14.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Tudor_4 PF18358.1 GAX20068.1 - 0.11 12.2 0.1 0.26 10.9 0.1 1.7 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain E2F_CC-MB PF16421.5 GAX20069.1 - 2.2e-22 79.2 0.0 3.7e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 GAX20069.1 - 2.3e-21 75.6 0.0 3.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain COMMD1_N PF17221.3 GAX20069.1 - 0.053 13.8 0.0 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 COMMD1 N-terminal domain VPS9 PF02204.18 GAX20070.1 - 3.9e-14 52.7 0.0 1.3e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain PDZ_6 PF17820.1 GAX20070.1 - 1.6e-07 31.1 0.4 3.9e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX20070.1 - 1.4e-05 25.3 0.0 3.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX20070.1 - 0.00014 22.1 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PX PF00787.24 GAX20070.1 - 0.011 15.6 0.0 0.04 13.9 0.0 1.9 2 0 0 2 2 2 0 PX domain Hydrolase_4 PF12146.8 GAX20071.1 - 5.1e-17 61.9 0.1 4e-13 49.2 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GAX20071.1 - 1.6e-09 37.8 0.2 2.6e-06 27.2 0.0 2.9 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAX20071.1 - 1.4e-07 31.4 0.1 6e-06 26.1 0.1 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX20071.1 - 1.4e-06 29.1 0.1 3.3e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX20071.1 - 1.8e-06 27.6 1.0 0.0015 18.0 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family FSH1 PF03959.13 GAX20071.1 - 1.2e-05 25.0 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 GAX20071.1 - 0.0018 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_M14 PF00246.24 GAX20072.1 - 7.9e-16 58.7 0.0 5.3e-14 52.7 0.0 2.4 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF4460 PF14687.6 GAX20072.1 - 0.038 14.0 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) RVT_2 PF07727.14 GAX20073.1 - 1.7e-17 63.9 0.0 2.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MazE_antitoxin PF04014.18 GAX20073.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin polyprenyl_synt PF00348.17 GAX20074.1 - 1.2e-96 322.7 0.0 1.5e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YhhN PF07947.14 GAX20074.1 - 0.022 14.4 0.6 0.043 13.4 0.6 1.4 1 0 0 1 1 1 0 YhhN family DUF1800 PF08811.11 GAX20075.1 - 4.6e-43 147.8 0.0 1.3e-25 90.4 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX20075.1 - 4.5e-32 111.6 0.0 8.5e-32 110.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX20075.1 - 5.5e-05 23.2 0.1 0.00035 20.7 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Dicty_CTDC PF00526.18 GAX20077.1 - 2.6e-07 30.4 5.0 2.6e-07 30.4 5.0 3.7 3 0 0 3 3 3 1 Dictyostelium (slime mold) repeat TraW_N PF12477.8 GAX20078.1 - 0.02 14.8 0.2 0.037 14.0 0.2 1.4 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal DUF1800 PF08811.11 GAX20079.1 - 1.5e-41 142.9 0.0 3.4e-26 92.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX20079.1 - 1.1e-33 116.9 0.0 1.8e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF4653 PF15546.6 GAX20079.1 - 0.11 12.1 0.0 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) DUF1800 PF08811.11 GAX20080.1 - 1.9e-48 165.6 0.1 4.5e-27 95.1 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX20080.1 - 1.6e-29 103.2 3.2 2.2e-28 99.4 3.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX20080.1 - 0.0011 19.1 0.0 0.0041 17.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1800 PF08811.11 GAX20082.1 - 6.9e-47 160.4 0.0 5.2e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX20082.1 - 1.8e-29 103.0 1.6 1.5e-28 100.0 1.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) NARG2_C PF10505.9 GAX20082.1 - 0.17 11.4 0.2 0.36 10.3 0.2 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus DUF1800 PF08811.11 GAX20083.1 - 5.5e-47 160.8 0.0 1e-27 97.3 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX20083.1 - 4.9e-29 101.6 2.0 4.5e-28 98.4 2.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX20083.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain FPL PF09758.9 GAX20084.1 - 1.6e-23 83.3 0.4 3.6e-22 78.9 0.4 2.4 1 1 0 1 1 1 1 Uncharacterised conserved protein DUF1800 PF08811.11 GAX20085.1 - 1.7e-42 146.0 0.0 1.5e-25 90.1 0.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX20085.1 - 4e-31 108.5 0.6 3.9e-30 105.2 0.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX20085.1 - 6.2e-05 23.1 0.0 0.00025 21.2 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DHHC PF01529.20 GAX20086.1 - 7e-25 87.7 0.6 7e-25 87.7 0.6 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase YL1 PF05764.13 GAX20087.1 - 0.0003 21.0 28.8 0.0003 21.0 28.8 2.2 1 1 1 2 2 1 1 YL1 nuclear protein Sporozoite_P67 PF05642.11 GAX20087.1 - 0.0034 15.6 21.3 0.019 13.1 11.4 2.1 2 0 0 2 2 2 2 Sporozoite P67 surface antigen RNase_H2_suC PF08615.11 GAX20087.1 - 0.0034 17.6 11.1 2.9e+02 1.6 11.1 3.3 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SpoIIIAH PF12685.7 GAX20087.1 - 0.021 14.6 17.9 0.047 13.5 11.7 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Rtf2 PF04641.12 GAX20087.1 - 0.14 11.5 17.2 0.038 13.4 13.1 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger Mpp10 PF04006.12 GAX20087.1 - 0.2 10.1 41.1 0.58 8.5 29.1 2.1 2 0 0 2 2 2 0 Mpp10 protein RNA_pol_Rpc4 PF05132.14 GAX20087.1 - 0.23 11.9 16.2 0.39 11.1 11.6 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 eIF3_subunit PF08597.10 GAX20087.1 - 0.25 11.2 39.8 0.15 11.9 28.5 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CPSF100_C PF13299.6 GAX20087.1 - 0.52 10.5 18.5 0.73 10.0 11.9 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 GAX20087.1 - 0.63 9.2 13.0 0.47 9.6 9.5 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter SDA1 PF05285.12 GAX20087.1 - 0.7 9.3 47.5 0.11 11.9 30.0 2.4 3 0 0 3 3 3 0 SDA1 Cwf_Cwc_15 PF04889.12 GAX20087.1 - 0.91 9.2 44.9 0.6 9.8 28.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TRAP_alpha PF03896.16 GAX20087.1 - 2 7.6 23.3 0.33 10.1 0.6 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ctr PF04145.15 GAX20087.1 - 4.7 7.8 9.1 0.64 10.6 0.1 3.0 2 1 0 2 2 2 0 Ctr copper transporter family Merozoite_SPAM PF07133.11 GAX20087.1 - 5.4 7.0 55.9 0.41 10.6 36.5 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) FAM163 PF15069.6 GAX20087.1 - 5.7 7.4 7.9 3 8.3 2.2 2.4 2 0 0 2 2 2 0 FAM163 family CobT PF06213.12 GAX20087.1 - 6.5 6.1 40.2 1.5 8.2 25.5 2.4 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GAX20087.1 - 9.4 4.4 50.2 0.028 12.7 29.0 2.1 1 1 1 2 2 2 0 CDC45-like protein RINGv PF12906.7 GAX20088.1 - 2.1e-11 43.8 7.9 4.2e-11 42.8 7.9 1.5 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 GAX20088.1 - 1.4e-09 38.1 0.0 6.6e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAX20088.1 - 0.00018 21.7 0.0 0.00063 20.0 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain EF-hand_7 PF13499.6 GAX20088.1 - 0.12 12.9 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-RING_2 PF13639.6 GAX20088.1 - 0.56 10.6 8.6 12 6.4 9.7 2.3 1 1 1 2 2 2 0 Ring finger domain FANCL_C PF11793.8 GAX20088.1 - 3 8.1 9.2 1.7 8.9 7.3 1.6 2 0 0 2 2 2 0 FANCL C-terminal domain zf-MYND PF01753.18 GAX20089.1 - 2.2e-09 37.3 18.2 4.8e-09 36.2 18.2 1.6 1 0 0 1 1 1 1 MYND finger Thioredoxin_5 PF13743.6 GAX20089.1 - 0.08 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin ThiF PF00899.21 GAX20089.1 - 0.093 12.1 0.1 0.095 12.0 0.1 1.2 1 0 0 1 1 1 0 ThiF family zf-Mss51 PF13824.6 GAX20089.1 - 1.7 8.8 13.6 1.2 9.3 11.5 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 GAX20089.1 - 2.5 8.2 10.3 7.9 6.6 10.3 1.9 1 1 0 1 1 1 0 Double zinc ribbon tRNA-synt_1d PF00750.19 GAX20090.1 - 1.7e-122 408.8 0.0 2.7e-122 408.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAX20090.1 - 9.8e-30 103.2 1.5 1.5e-29 102.6 0.1 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAX20090.1 - 1.4e-18 67.3 0.5 6.9e-18 65.0 0.2 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 GAX20090.1 - 0.00012 21.6 2.4 0.00015 21.3 0.0 2.3 3 1 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 GAX20090.1 - 0.0011 17.3 0.2 0.029 12.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) TFIIF_alpha PF05793.12 GAX20090.1 - 0.013 14.1 7.5 0.021 13.4 7.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rrp44_CSD1 PF17216.3 GAX20090.1 - 0.027 14.2 3.6 0.07 12.9 3.6 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain tRNA-synt_1g PF09334.11 GAX20090.1 - 0.043 12.6 0.1 0.084 11.6 0.1 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (M) POX PF07526.11 GAX20090.1 - 0.32 11.6 3.0 0.83 10.2 1.9 2.3 3 0 0 3 3 3 0 Associated with HOX FAM176 PF14851.6 GAX20090.1 - 0.38 10.4 3.7 1.1 9.0 3.7 1.7 1 0 0 1 1 1 0 FAM176 family DTHCT PF08070.11 GAX20090.1 - 0.68 10.7 12.8 1.5 9.6 6.5 2.9 3 0 0 3 3 3 0 DTHCT (NUC029) region RsmJ PF04378.13 GAX20091.1 - 7.3e-20 71.2 0.0 1.8e-19 70.0 0.0 1.6 1 1 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ TB2_DP1_HVA22 PF03134.19 GAX20092.1 - 3.9e-25 87.6 2.3 3.9e-25 87.6 2.3 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family zf-CGNR PF11706.8 GAX20093.1 - 0.048 13.5 0.8 0.048 13.5 0.8 2.3 2 0 0 2 2 2 0 CGNR zinc finger MscS_TM PF12794.7 GAX20093.1 - 0.98 8.2 2.1 1.6 7.5 2.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 CxxCxxCC PF03692.15 GAX20093.1 - 1.7 9.4 9.2 0.087 13.5 3.4 1.8 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain CxC6 PF18721.1 GAX20093.1 - 6.4 7.1 11.8 0.44 10.9 5.8 2.1 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases SUI1 PF01253.22 GAX20094.1 - 4.9e-25 87.9 1.7 5.9e-25 87.6 1.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Hydrophob_seed PF14547.6 GAX20094.1 - 0.023 14.9 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Hydrophobic seed protein Dus PF01207.17 GAX20094.1 - 0.069 12.2 0.2 0.1 11.6 0.2 1.4 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) TFIIF_alpha PF05793.12 GAX20095.1 - 0.0098 14.5 3.6 0.016 13.9 3.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ATAD4 PF15321.6 GAX20095.1 - 0.04 15.3 1.1 0.11 13.8 1.1 1.7 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 UCH PF00443.29 GAX20096.1 - 3.3e-69 233.3 0.3 3.3e-69 233.3 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX20096.1 - 1.8e-15 57.3 5.5 6.4e-15 55.6 0.1 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PriX PF18689.1 GAX20096.1 - 0.12 12.7 0.1 6.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Primase X CEBP_ZZ PF16366.5 GAX20096.1 - 0.83 9.9 0.0 0.83 9.9 0.0 3.2 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Erv26 PF04148.13 GAX20098.1 - 0.028 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 Tetraspanin PF00335.20 GAX20099.1 - 0.0029 17.4 0.5 0.017 14.8 0.0 2.2 1 1 0 2 2 2 1 Tetraspanin family DUF4229 PF14012.6 GAX20099.1 - 0.19 11.9 0.1 0.19 11.9 0.1 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) PIRT PF15099.6 GAX20100.1 - 0.43 10.2 4.5 0.38 10.3 0.9 2.4 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Xan_ur_permease PF00860.20 GAX20102.1 - 2.6e-25 89.0 29.2 4.4e-15 55.3 12.5 2.7 2 1 0 2 2 2 2 Permease family DUF5464 PF17552.2 GAX20102.1 - 0.0077 16.5 0.2 0.08 13.2 0.0 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5464) Wzy_C PF04932.15 GAX20102.1 - 0.053 13.2 12.5 0.14 11.8 0.7 2.9 2 1 0 2 2 2 0 O-Antigen ligase MFS_MOT1 PF16983.5 GAX20102.1 - 1.8 9.0 22.9 0.34 11.3 2.5 3.4 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily Pyr_redox_2 PF07992.14 GAX20104.1 - 9.1e-14 51.4 0.1 1.6e-13 50.6 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.6 GAX20104.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Glutaredoxin2_C PF04399.13 GAX20106.1 - 2.5e-29 101.7 0.0 1e-27 96.6 0.0 2.1 1 1 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 GAX20106.1 - 1.7e-05 25.1 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX20106.1 - 0.0032 17.7 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAX20106.1 - 0.053 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin RHD3 PF05879.12 GAX20108.1 - 0.076 11.1 0.1 0.1 10.7 0.1 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Sigma70_r3 PF04539.16 GAX20109.1 - 2.3e-18 66.1 2.0 9.7e-13 48.0 0.3 3.5 3 0 0 3 3 3 3 Sigma-70 region 3 Sigma70_r2 PF04542.14 GAX20109.1 - 2.3e-15 56.1 0.0 5.2e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GAX20109.1 - 1.3e-10 40.6 0.0 7.3e-10 38.2 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_15 PF12324.8 GAX20109.1 - 0.096 12.7 0.1 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase CbtA PF09490.10 GAX20110.1 - 1.4 8.6 4.1 2.1 8.0 4.1 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Coatomer_WDAD PF04053.14 GAX20111.1 - 1.6e-104 350.4 0.0 2.3e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 GAX20111.1 - 4.9e-93 312.1 0.0 7.2e-93 311.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 GAX20111.1 - 4.2e-41 138.2 16.8 1.6e-07 31.8 0.4 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX20111.1 - 5e-11 42.8 0.2 0.00014 22.1 0.1 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX20111.1 - 0.0023 16.6 1.6 0.16 10.6 0.0 3.1 1 1 2 3 3 3 1 Nucleoporin Nup120/160 CDP-OH_P_transf PF01066.21 GAX20112.1 - 5.3e-14 52.7 0.3 5.3e-14 52.7 0.3 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribosomal_L37ae PF01780.19 GAX20113.1 - 1.1e-40 137.6 8.2 1.3e-40 137.4 8.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 GAX20113.1 - 0.12 12.4 4.2 0.19 11.8 4.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain MerR_1 PF13411.6 GAX20114.1 - 0.035 14.2 0.1 5.7 7.1 0.0 2.2 2 0 0 2 2 2 0 MerR HTH family regulatory protein CDC45 PF02724.14 GAX20115.1 - 1.6 6.9 5.4 1.8 6.8 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Usp PF00582.26 GAX20115.1 - 2.1 8.8 4.6 4.9 7.6 4.6 1.7 1 1 0 1 1 1 0 Universal stress protein family DUF2370 PF10176.9 GAX20115.1 - 6.4 6.4 6.0 4.9 6.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) MMR_HSR1 PF01926.23 GAX20116.1 - 2e-21 76.2 0.0 4.4e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 GAX20116.1 - 5e-17 61.5 0.9 9.7e-17 60.6 0.9 1.5 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.23 GAX20116.1 - 1.8e-09 37.9 0.1 5.8e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 GAX20116.1 - 5.5e-09 35.7 0.1 1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAX20116.1 - 1.4e-06 28.0 0.0 0.0025 17.4 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX20116.1 - 4.2e-05 23.5 0.1 0.0074 16.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 GAX20116.1 - 0.00084 19.1 0.2 0.0051 16.6 0.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 GAX20116.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 GAX20116.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX20116.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arabinose_trans PF04602.12 GAX20116.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein SRPRB PF09439.10 GAX20116.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAX20116.1 - 0.15 12.4 0.0 0.68 10.3 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Clathrin PF00637.20 GAX20117.1 - 2.2e-155 510.7 19.9 6e-25 87.8 2.7 8.2 8 1 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 GAX20117.1 - 5.8e-27 93.4 0.9 2.7e-26 91.3 0.2 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 GAX20117.1 - 1.1e-08 34.9 0.9 0.0065 16.7 0.0 5.0 5 0 0 5 5 5 2 Clathrin propeller repeat Clathrin-link PF09268.10 GAX20117.1 - 2.8e-06 26.6 1.4 2.4e-05 23.6 0.7 2.6 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 GAX20117.1 - 0.00023 20.9 0.5 2.5 8.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX20117.1 - 0.0027 17.7 9.8 2.6 8.4 0.3 7.1 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF1512 PF07431.12 GAX20117.1 - 0.064 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF3440 PF11922.8 GAX20117.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) TPR_12 PF13424.6 GAX20117.1 - 0.12 12.7 1.1 53 4.2 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20117.1 - 0.25 11.6 5.7 22 5.6 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX20117.1 - 0.27 11.1 9.6 2.3 8.2 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX20117.1 - 2.8 8.2 15.0 1.8 8.8 0.6 5.5 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAX20117.1 - 9.3 7.1 6.6 1.1e+02 3.8 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat CTP_transf_like PF01467.26 GAX20118.1 - 9.4e-09 35.6 0.0 1.1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like PPR_long PF17177.4 GAX20119.1 - 0.0056 16.1 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Rieske PF00355.26 GAX20120.1 - 1.2e-09 38.0 0.0 8.6e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 GAX20120.1 - 2.8e-08 33.6 0.0 0.00012 21.9 0.0 2.4 1 1 1 2 2 2 2 Rieske-like [2Fe-2S] domain EGF PF00008.27 GAX20121.1 - 4.2e-05 23.7 36.4 0.0016 18.7 4.5 4.0 3 1 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 GAX20121.1 - 0.0029 17.9 6.1 0.0029 17.9 6.1 4.2 3 2 0 3 3 3 2 EGF-like domain EGF_alliinase PF04863.13 GAX20121.1 - 0.019 15.4 13.3 0.019 15.4 13.3 3.7 2 1 1 3 3 3 0 Alliinase EGF-like domain DotD PF16816.5 GAX20122.1 - 0.17 11.9 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 DotD protein WD40 PF00400.32 GAX20123.1 - 1.9e-19 69.6 15.3 0.0002 22.1 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-CCCH PF00642.24 GAX20123.1 - 1.8e-06 27.7 1.6 6.5e-06 25.9 0.6 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAX20123.1 - 2.1e-05 24.4 2.8 2.1e-05 24.4 2.8 1.9 2 0 0 2 2 2 1 Zinc finger domain ANAPC4_WD40 PF12894.7 GAX20123.1 - 2.9e-05 24.3 0.4 3.9 7.8 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-CCCH_4 PF18044.1 GAX20123.1 - 3.5e-05 23.5 1.6 8.9e-05 22.2 1.6 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger Nup160 PF11715.8 GAX20123.1 - 0.0028 16.4 0.5 0.17 10.5 0.0 3.0 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAX20123.1 - 0.0043 15.9 0.0 0.034 12.9 0.0 2.6 2 1 0 3 3 3 1 Nup133 N terminal like Torus PF16131.5 GAX20123.1 - 0.091 13.5 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 GAX20123.1 - 0.3 11.6 3.2 0.9 10.1 3.2 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF4392 PF14336.6 GAX20124.1 - 2e-84 283.6 0.0 2.4e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) ATPgrasp_N PF18130.1 GAX20124.1 - 0.0018 18.8 0.0 0.0077 16.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-synt_ab PF00006.25 GAX20125.1 - 9.3e-74 247.7 0.0 1.6e-73 246.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 GAX20125.1 - 5.8e-42 143.0 0.1 8.7e-42 142.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 GAX20125.1 - 5.2e-18 65.3 2.4 1e-17 64.4 2.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 GAX20125.1 - 0.0017 18.4 1.3 0.0048 17.0 1.3 1.8 1 0 0 1 1 1 1 HAS barrel domain Radical_SAM_C PF16199.5 GAX20125.1 - 0.033 14.2 0.0 0.089 12.8 0.0 1.7 2 0 0 2 2 2 0 Radical_SAM C-terminal domain BT1 PF03092.16 GAX20126.1 - 3e-86 289.8 11.2 4.5e-47 160.5 1.5 3.0 1 1 1 2 2 2 2 BT1 family MFS_1_like PF12832.7 GAX20126.1 - 7.7e-06 25.0 0.0 1.2e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 MFS_1 like family ATP19 PF11022.8 GAX20126.1 - 0.098 13.0 1.2 0.18 12.2 0.1 2.1 2 0 0 2 2 2 0 ATP synthase subunit K HHH_2 PF12826.7 GAX20127.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pkinase PF00069.25 GAX20128.1 - 4.3e-54 183.6 0.0 1.1e-53 182.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX20128.1 - 7.6e-52 176.2 0.0 1.2e-51 175.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NIT PF08376.10 GAX20128.1 - 1.4e-12 48.6 0.3 5.5e-05 23.8 0.2 2.4 2 0 0 2 2 2 2 Nitrate and nitrite sensing Pkinase_fungal PF17667.1 GAX20128.1 - 7.8e-08 31.5 0.0 3.6e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAX20128.1 - 0.052 12.9 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 GAX20128.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 GAX20128.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_2 PF07727.14 GAX20129.1 - 5.3e-21 75.4 0.3 1.8e-20 73.6 0.3 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX20129.1 - 0.027 14.5 0.9 0.063 13.4 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Diphthamide_syn PF01866.17 GAX20129.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative diphthamide synthesis protein PK PF00224.21 GAX20130.1 - 3.2e-115 384.8 0.4 4e-115 384.4 0.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAX20130.1 - 5e-11 42.9 0.2 1.9e-10 41.0 0.2 2.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAX20130.1 - 0.00032 19.9 0.6 0.00063 18.9 0.6 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Glyco_hydro_3_C PF01915.22 GAX20130.1 - 0.022 14.7 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain PixA PF12306.8 GAX20130.1 - 0.025 14.8 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Inclusion body protein DUF4838 PF16126.5 GAX20130.1 - 0.1 12.0 0.3 0.16 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Cuticle_3 PF11018.8 GAX20130.1 - 3.5 7.8 10.5 6.2 7.0 5.2 2.2 1 1 1 2 2 2 0 Pupal cuticle protein C1 Alg14 PF08660.11 GAX20131.1 - 4.2e-54 183.1 0.0 7.1e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Hum_adeno_E3A PF05393.11 GAX20131.1 - 0.041 13.9 1.0 0.08 12.9 0.5 1.8 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein DUF1995 PF09353.10 GAX20132.1 - 3.9e-27 95.6 0.0 5.5e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Pyrophosphatase PF00719.19 GAX20133.1 - 1.4e-52 177.7 0.2 1.7e-52 177.5 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF1180 PF06679.12 GAX20134.1 - 0.011 16.2 2.8 0.026 15.0 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SPX PF03105.19 GAX20134.1 - 1.2 9.0 7.2 1.3 8.8 7.2 1.2 1 0 0 1 1 1 0 SPX domain FAM199X PF15814.5 GAX20134.1 - 3.2 6.7 13.3 4.6 6.2 13.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Macoilin PF09726.9 GAX20134.1 - 8.9 4.7 6.3 8.8 4.7 6.3 1.1 1 0 0 1 1 1 0 Macoilin family Rad60-SLD PF11976.8 GAX20135.1 - 1e-07 31.7 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like GRDP-like PF07173.12 GAX20135.1 - 0.04 14.6 0.0 0.068 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like ubiquitin PF00240.23 GAX20135.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family zf-Tim10_DDP PF02953.15 GAX20137.1 - 2e-18 65.8 4.6 2.9e-18 65.3 4.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mito_carr PF00153.27 GAX20138.1 - 1.6e-15 56.8 1.9 0.0067 16.3 0.1 4.6 3 2 1 4 4 4 4 Mitochondrial carrier protein Arrestin_N PF00339.29 GAX20139.1 - 1.9e-11 44.3 0.1 7.4e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAX20139.1 - 1.8e-09 38.2 0.1 2e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 GAX20139.1 - 0.031 14.0 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like Ribosomal_S7 PF00177.21 GAX20140.1 - 3.4e-35 120.9 0.5 4.1e-35 120.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AAA PF00004.29 GAX20141.1 - 4.8e-33 114.4 0.0 1.2e-32 113.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX20141.1 - 1.1e-06 28.4 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAX20141.1 - 8.7e-05 22.8 0.3 0.002 18.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAX20141.1 - 0.00013 21.2 0.1 0.00027 20.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAX20141.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX20141.1 - 0.00085 19.3 0.1 0.0036 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAX20141.1 - 0.0011 19.5 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 GAX20141.1 - 0.0011 18.4 0.0 1.3 8.4 0.0 2.5 1 1 1 2 2 2 2 Bacterial TniB protein IstB_IS21 PF01695.17 GAX20141.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 GAX20141.1 - 0.0021 17.4 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 GAX20141.1 - 0.0068 15.8 0.3 0.027 13.8 0.2 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GAX20141.1 - 0.011 16.1 7.5 0.037 14.4 0.0 3.3 3 2 1 4 4 3 0 AAA ATPase domain AAA_7 PF12775.7 GAX20141.1 - 0.018 14.6 0.0 0.068 12.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 GAX20141.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 GAX20141.1 - 0.025 14.8 0.8 0.07 13.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAX20141.1 - 0.031 14.2 0.2 0.15 11.9 0.1 2.1 1 1 1 2 2 2 0 NACHT domain AAA_2 PF07724.14 GAX20141.1 - 0.04 14.0 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 GAX20141.1 - 0.046 14.1 0.0 0.24 11.8 0.0 2.3 2 1 0 2 2 2 0 RNA helicase AAA_3 PF07726.11 GAX20141.1 - 0.083 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAX20141.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 GAX20141.1 - 0.22 11.8 0.6 16 5.7 0.0 2.8 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain NmrA PF05368.13 GAX20142.1 - 4e-39 134.5 0.2 3.2e-22 79.2 0.4 3.2 3 0 0 3 3 3 3 NmrA-like family NAD_binding_10 PF13460.6 GAX20142.1 - 1.5e-11 44.6 0.2 2.9e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 GAX20142.1 - 1.4e-05 24.7 0.3 0.00018 21.1 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX20142.1 - 0.00014 21.0 0.7 0.036 13.1 0.1 2.5 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 GAX20142.1 - 0.0087 15.5 0.2 0.34 10.3 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PALP PF00291.25 GAX20142.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme SRP40_C PF05022.12 GAX20143.1 - 1.1e-21 77.5 1.7 4.9e-21 75.4 1.7 2.3 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.11 GAX20143.1 - 0.1 12.6 0.5 0.2 11.7 0.5 1.5 1 0 0 1 1 1 0 LisH Ribosomal_S10 PF00338.22 GAX20144.1 - 1.5e-27 95.7 0.1 1.8e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NnrU PF07298.11 GAX20145.1 - 2.3e-41 141.6 9.3 4.9e-41 140.6 9.3 1.5 1 0 0 1 1 1 1 NnrU protein PEMT PF04191.13 GAX20145.1 - 0.002 18.5 0.1 0.002 18.5 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF2105 PF09878.9 GAX20145.1 - 0.022 14.5 0.4 0.022 14.5 0.4 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2105) DUF1048 PF06304.11 GAX20145.1 - 0.11 12.9 0.0 8 7.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1048) Peptidase_S9_N PF02897.15 GAX20146.1 - 4.4e-74 249.7 0.1 6.5e-74 249.2 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 GAX20146.1 - 1.6e-12 47.4 0.0 3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family ATP12 PF07542.11 GAX20148.1 - 3.9e-28 98.1 1.0 9.7e-28 96.8 1.0 1.8 1 1 0 1 1 1 1 ATP12 chaperone protein SWIRM-assoc_2 PF16496.5 GAX20149.1 - 0.011 14.7 4.6 0.019 13.9 4.6 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF1769 PF08588.10 GAX20149.1 - 0.026 14.7 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CLP_protease PF00574.23 GAX20150.1 - 1e-79 266.6 0.0 1.3e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease PurA PF04845.13 GAX20150.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein NAD_binding_1 PF00175.21 GAX20151.1 - 2.8e-29 102.0 0.0 3.4e-28 98.5 0.0 2.1 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX20151.1 - 0.005 17.2 0.0 0.0095 16.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain tRNA-synt_1c PF00749.21 GAX20152.1 - 6.2e-97 324.3 0.0 2.1e-96 322.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_bind PF01588.20 GAX20152.1 - 1.4e-27 95.6 0.0 2.7e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain DUF4537 PF15057.6 GAX20152.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Cyto_heme_lyase PF01265.17 GAX20154.1 - 1.7e-43 149.3 17.8 4.1e-23 82.4 6.1 2.6 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase Ldh_1_C PF02866.18 GAX20155.1 - 3.7e-44 150.6 0.0 1.3e-43 148.9 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAX20155.1 - 4.2e-42 143.6 0.1 5.9e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAX20155.1 - 4.8e-05 22.5 0.0 8.4e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CPSase_L_D2 PF02786.17 GAX20156.1 - 3.5e-110 366.5 0.5 2.2e-80 269.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAX20156.1 - 1.5e-51 173.5 0.0 3.7e-51 172.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAX20156.1 - 8.2e-42 143.1 0.0 7.4e-41 140.0 0.0 2.6 3 0 0 3 3 3 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 GAX20156.1 - 2.9e-38 131.0 0.6 1e-37 129.2 0.6 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 GAX20156.1 - 1.3e-17 63.9 0.3 5.7e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAX20156.1 - 3.2e-17 62.7 0.4 1.3e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 GAX20156.1 - 6.2e-17 61.6 0.0 5.3e-16 58.6 0.0 2.8 3 0 0 3 3 2 1 MGS-like domain ATPgrasp_Ter PF15632.6 GAX20156.1 - 6.6e-12 45.3 0.0 2.2e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 GAX20156.1 - 2e-07 31.2 0.2 0.00062 19.9 0.0 3.4 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 GAX20156.1 - 0.0012 18.6 0.5 0.066 13.0 0.5 2.5 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 GAX20156.1 - 0.028 14.2 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain FTO_CTD PF12934.7 GAX20156.1 - 0.08 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 FTO C-terminal domain Peptidase_M17_N PF02789.17 GAX20156.1 - 0.099 12.5 0.2 0.34 10.8 0.0 2.0 2 0 0 2 2 1 0 Cytosol aminopeptidase family, N-terminal domain DUF5371 PF17341.2 GAX20156.1 - 0.13 12.5 0.1 0.79 10.0 0.0 2.4 2 0 0 2 2 1 0 Family of unknown function (DUF5371) UBA_6 PF18039.1 GAX20156.1 - 0.13 12.2 0.0 7.3 6.6 0.0 3.5 3 0 0 3 3 3 0 UBA-like domain ATP-grasp_5 PF13549.6 GAX20156.1 - 0.13 11.7 0.0 12 5.2 0.0 2.9 3 0 0 3 3 3 0 ATP-grasp domain DUF5333 PF17267.2 GAX20156.1 - 0.16 12.1 0.1 0.66 10.2 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5333) EF-hand_7 PF13499.6 GAX20157.1 - 6.6e-10 39.3 4.6 6.6e-10 39.3 4.6 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX20157.1 - 1e-08 34.1 3.3 4.6e-06 25.8 0.5 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX20157.1 - 1.4e-08 34.0 3.0 3.3e-05 23.5 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain Na_Ca_ex PF01699.24 GAX20157.1 - 2.9e-08 33.8 22.8 1.6e-06 28.1 9.8 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_8 PF13833.6 GAX20157.1 - 5.2e-07 29.4 2.8 6.4e-07 29.1 1.2 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GAX20157.1 - 1.7e-05 24.1 1.8 7.7e-05 22.0 0.5 2.4 2 0 0 2 2 2 1 EF hand Cyclin_N PF00134.23 GAX20158.1 - 7e-15 54.9 0.7 1.1e-14 54.2 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX20158.1 - 0.00054 20.0 0.1 0.0022 18.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain SF-assemblin PF06705.11 GAX20159.1 - 4.4e-23 81.9 28.1 5.4e-23 81.6 28.1 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 GAX20159.1 - 0.0006 19.9 10.1 0.038 14.0 1.1 3.0 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 GAX20159.1 - 0.0076 16.3 26.1 0.19 11.8 5.9 3.1 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) YlqD PF11068.8 GAX20159.1 - 0.0094 16.3 6.7 0.0094 16.3 6.7 3.3 1 1 2 3 3 3 1 YlqD protein DUF885 PF05960.11 GAX20159.1 - 0.22 11.1 13.7 0.31 10.6 13.7 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) SCP2 PF02036.17 GAX20159.1 - 0.33 11.5 2.9 2.9 8.4 0.1 2.5 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF3584 PF12128.8 GAX20159.1 - 0.71 7.3 34.7 1.2 6.5 34.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Fzo_mitofusin PF04799.13 GAX20159.1 - 2.3 7.8 18.7 0.034 13.7 5.0 3.3 1 1 4 5 5 5 0 fzo-like conserved region Borrelia_orfA PF02414.15 GAX20159.1 - 4.9 6.7 16.5 6.2 6.4 13.4 2.0 1 1 1 2 2 2 0 Borrelia ORF-A DUF1993 PF09351.10 GAX20159.1 - 8.7 6.5 11.8 3.5 7.7 0.5 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) DUF1674 PF07896.12 GAX20160.1 - 2e-10 41.0 6.1 6.3e-10 39.4 6.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) SNAD2 PF18745.1 GAX20160.1 - 0.068 12.9 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 DUF501 PF04417.12 GAX20161.1 - 1.2e-33 115.9 0.0 1.6e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Nop PF01798.18 GAX20162.1 - 7.9e-90 300.3 0.7 1.6e-89 299.3 0.7 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAX20162.1 - 8.5e-18 64.5 0.5 8.5e-18 64.5 0.5 2.9 3 1 0 3 3 3 1 NOP5NT (NUC127) domain DUF3245 PF11595.8 GAX20162.1 - 0.072 13.6 20.4 0.18 12.3 20.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) U79_P34 PF03064.16 GAX20162.1 - 0.61 9.4 20.9 0.9 8.8 20.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Cdh1_DBD_1 PF18196.1 GAX20162.1 - 1.2 9.5 14.1 3.2 8.1 14.1 1.7 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF4604 PF15377.6 GAX20162.1 - 3.5 8.0 29.4 7.2 7.0 29.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PBP1_TM PF14812.6 GAX20162.1 - 5.6 7.4 20.7 11 6.5 20.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DnaJ-X PF14308.6 GAX20164.1 - 1e-33 116.6 0.3 1e-33 116.6 0.3 2.8 2 2 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAX20164.1 - 5e-24 84.2 0.9 1.7e-23 82.5 0.9 2.0 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L15e PF00827.17 GAX20165.1 - 2e-91 304.9 7.2 2.3e-91 304.7 7.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L28e PF01778.17 GAX20166.1 - 1.9e-23 83.4 2.4 2.3e-23 83.1 2.4 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family 2OG-FeII_Oxy_3 PF13640.6 GAX20167.1 - 2.8e-15 57.0 0.1 7.9e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily LRR_6 PF13516.6 GAX20168.1 - 6.1e-06 25.9 2.4 1.1 9.5 0.0 6.0 7 0 0 7 7 7 3 Leucine Rich repeat AAA_2 PF07724.14 GAX20169.1 - 6.8e-40 137.0 0.1 4e-33 114.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAX20169.1 - 2.1e-15 57.3 0.1 2.5e-06 27.9 0.1 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX20169.1 - 1.2e-08 35.0 0.1 2.3e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX20169.1 - 2.2e-06 28.2 0.4 2.3e-05 24.8 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain ClpB_D2-small PF10431.9 GAX20169.1 - 4.7e-06 26.6 0.6 4.7e-06 26.6 0.6 1.9 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 GAX20169.1 - 1.5e-05 24.3 0.0 0.0041 16.2 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain G-alpha PF00503.20 GAX20169.1 - 2.2e-05 23.8 0.0 3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 GAX20169.1 - 5.4e-05 23.5 0.1 0.00044 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX20169.1 - 0.00037 20.7 0.2 0.0053 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAX20169.1 - 0.00066 19.1 0.3 0.014 14.8 0.0 2.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 GAX20169.1 - 0.0013 18.5 1.2 0.29 10.9 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 GAX20169.1 - 0.0015 18.3 0.0 0.042 13.5 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAX20169.1 - 0.0023 17.3 0.1 0.0065 15.8 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin SseC PF04888.12 GAX20169.1 - 0.0029 17.3 2.8 0.3 10.6 0.2 2.1 2 0 0 2 2 2 2 Secretion system effector C (SseC) like family TIP49 PF06068.13 GAX20169.1 - 0.0075 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 GAX20169.1 - 0.0096 15.3 0.1 0.059 12.8 0.0 2.3 2 1 0 2 2 2 1 Bacterial TniB protein SKI PF01202.22 GAX20169.1 - 0.0097 16.0 0.1 4.7 7.3 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase NACHT PF05729.12 GAX20169.1 - 0.022 14.7 0.1 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 GAX20169.1 - 0.023 15.0 0.7 0.16 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 GAX20169.1 - 0.025 14.3 0.1 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase Rad17 PF03215.15 GAX20169.1 - 0.027 14.4 0.0 0.17 11.8 0.0 2.0 1 1 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 GAX20169.1 - 0.031 14.3 0.1 7.5 6.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX20169.1 - 0.031 13.8 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 GAX20169.1 - 0.035 14.6 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 GAX20169.1 - 0.042 13.7 0.0 0.27 11.1 0.0 2.4 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein DUF2120 PF09893.9 GAX20169.1 - 0.061 13.4 1.7 1.4 9.1 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) TsaE PF02367.17 GAX20169.1 - 0.065 13.2 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAX20169.1 - 0.069 13.7 0.1 0.19 12.2 0.0 1.9 2 1 0 2 2 1 0 ABC transporter AAA_8 PF12780.7 GAX20169.1 - 0.095 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 RNA_helicase PF00910.22 GAX20169.1 - 0.11 12.9 0.0 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 GAX20169.1 - 0.57 10.5 4.0 0.5 10.7 0.2 2.4 2 1 0 2 2 2 0 AAA domain A_deaminase PF00962.22 GAX20170.1 - 1e-74 251.8 0.1 1.4e-74 251.4 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1168 PF06658.12 GAX20171.1 - 1.4e-25 89.7 13.9 1.7e-25 89.4 13.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DMRT-like PF15791.5 GAX20171.1 - 7.4 7.0 7.8 7.2 7.1 6.6 1.7 1 1 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 Presenilin PF01080.17 GAX20171.1 - 9.2 4.9 8.5 9.2 4.9 8.5 1.2 1 0 0 1 1 1 0 Presenilin HMG_box PF00505.19 GAX20172.1 - 5.5e-20 71.6 1.9 5.5e-20 71.6 1.9 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX20172.1 - 5.6e-07 30.1 3.6 1e-06 29.2 3.6 1.5 1 0 0 1 1 1 1 HMG-box domain Sec63 PF02889.16 GAX20173.1 - 3.2e-145 482.0 1.8 4.2e-78 262.1 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAX20173.1 - 7.4e-41 139.8 0.0 3.5e-25 88.8 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GAX20173.1 - 2.6e-25 88.7 1.5 2.6e-25 88.7 1.5 3.1 4 0 0 4 4 4 1 N-terminal helicase PWI domain ResIII PF04851.15 GAX20173.1 - 2.9e-20 73.0 0.0 2.1e-11 44.1 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX20173.1 - 2.5e-07 31.0 0.0 8e-06 26.2 0.0 3.2 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAX20173.1 - 0.0004 20.7 0.3 0.084 13.1 0.0 3.7 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAX20173.1 - 0.053 12.6 0.0 3.7 6.5 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 GAX20173.1 - 0.067 12.9 0.0 1.7 8.3 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF1149 PF06619.11 GAX20173.1 - 0.21 11.9 1.5 0.32 11.3 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1149) YL1 PF05764.13 GAX20173.1 - 0.47 10.5 13.6 1.1 9.3 13.6 1.6 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GAX20173.1 - 1.2 8.5 16.7 2.4 7.5 16.7 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GAX20173.1 - 2 7.7 12.9 3.7 6.8 12.9 1.4 1 0 0 1 1 1 0 BUD22 2OG-FeII_Oxy_2 PF13532.6 GAX20174.1 - 2.8e-08 34.2 0.0 3.2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CTD_bind PF04818.13 GAX20175.1 - 0.0026 18.6 1.5 0.0086 16.9 1.5 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Pyrophosphatase PF00719.19 GAX20176.1 - 1.1e-47 161.8 0.1 1.5e-47 161.4 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec66 PF09802.9 GAX20177.1 - 2.1e-12 47.0 9.8 2.4e-12 46.8 9.3 1.4 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 Gram_pos_anchor PF00746.21 GAX20177.1 - 0.093 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TRAP-gamma PF07074.12 GAX20177.1 - 3.2 7.3 4.2 6.7 6.2 4.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) CRT10 PF08728.10 GAX20177.1 - 4 5.5 6.3 5.2 5.1 6.3 1.1 1 0 0 1 1 1 0 CRT10 Stn1 PF10451.9 GAX20177.1 - 6.6 5.6 8.3 7.9 5.4 7.7 1.3 1 1 0 1 1 1 0 Telomere regulation protein Stn1 DUF726 PF05277.12 GAX20178.1 - 6.1e-76 255.6 6.5 8.3e-33 113.7 0.2 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF726) VirJ PF06057.11 GAX20178.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Strep_SA_rep PF06696.11 GAX20178.1 - 0.066 13.2 0.4 0.17 11.9 0.4 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Abhydrolase_6 PF12697.7 GAX20178.1 - 0.15 12.6 0.2 0.47 11.0 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4781 PF16013.5 GAX20178.1 - 6.1 5.6 5.0 11 4.7 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Yippee-Mis18 PF03226.14 GAX20179.1 - 5.8e-13 49.0 0.3 1.2e-12 48.0 0.3 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 GAX20179.1 - 0.033 14.4 0.7 0.057 13.7 0.7 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I FAM220 PF15487.6 GAX20179.1 - 0.036 13.7 0.9 0.045 13.4 0.9 1.1 1 0 0 1 1 1 0 FAM220 family zf_UBZ PF18439.1 GAX20179.1 - 0.11 12.1 1.4 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Roughex PF06020.11 GAX20180.1 - 2.9 6.9 10.1 0.046 12.8 1.4 1.9 2 0 0 2 2 2 0 Drosophila roughex protein Caskin-Pro-rich PF16907.5 GAX20180.1 - 3.6 8.2 8.9 41 4.8 8.9 2.4 1 1 0 1 1 1 0 Proline rich region of Caskin proteins Vta1 PF04652.16 GAX20181.1 - 3.1e-37 127.8 0.9 3.1e-37 127.8 0.9 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 GAX20181.1 - 0.0018 17.9 1.4 0.0018 17.9 1.4 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain DUF3090 PF11290.8 GAX20182.1 - 1.3 8.9 4.0 0.57 10.0 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3090) SOAR PF16533.5 GAX20182.1 - 4.9 7.2 7.4 0.47 10.4 0.8 2.7 3 1 1 4 4 4 0 STIM1 Orai1-activating region ArfGap PF01412.18 GAX20183.1 - 8.5e-32 109.7 0.1 1.3e-31 109.1 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf VitD-bind_III PF09164.10 GAX20183.1 - 0.084 12.9 0.2 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III 2-oxoacid_dh PF00198.23 GAX20184.1 - 4.4e-71 239.0 0.0 5.6e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX20184.1 - 7.1e-15 54.6 0.0 1.6e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAX20184.1 - 5.6e-12 45.8 0.1 1.3e-11 44.6 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain MgtE PF01769.16 GAX20185.1 - 1.7e-18 67.2 6.1 2.3e-18 66.7 6.1 1.2 1 0 0 1 1 1 1 Divalent cation transporter TPR_2 PF07719.17 GAX20186.1 - 6.9e-23 78.9 17.9 0.00029 20.7 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20186.1 - 4.4e-18 63.9 15.5 0.00061 19.8 0.0 9.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAX20186.1 - 1.5e-17 63.9 20.6 3.9e-08 33.7 4.6 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAX20186.1 - 3.1e-17 62.0 3.8 2.1e-05 24.1 0.0 6.6 5 1 1 6 6 6 3 TPR repeat TPR_17 PF13431.6 GAX20186.1 - 4.1e-16 58.1 9.6 0.023 15.0 0.2 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAX20186.1 - 7.2e-14 51.3 18.2 0.025 15.4 0.5 8.5 4 1 4 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX20186.1 - 2.6e-11 42.8 27.4 0.0058 16.4 0.0 8.9 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_21 PF09976.9 GAX20186.1 - 4.2e-10 39.7 4.5 4.2e-10 39.7 4.5 3.7 2 2 2 4 4 4 1 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 GAX20186.1 - 4.7e-10 39.9 21.4 0.0033 18.0 2.2 6.1 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAX20186.1 - 8.5e-06 25.8 11.2 0.0045 17.1 2.3 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 GAX20186.1 - 0.00092 19.2 2.2 1.5 9.0 0.1 4.3 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 GAX20186.1 - 0.0011 19.5 16.5 2.5 8.9 0.3 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX20186.1 - 0.0012 18.7 3.2 35 4.7 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 GAX20186.1 - 0.0018 17.2 10.4 0.078 11.9 0.0 3.5 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 GAX20186.1 - 0.0084 15.6 1.2 0.017 14.5 0.1 2.1 2 1 0 2 2 2 1 Coatomer epsilon subunit TPR_12 PF13424.6 GAX20186.1 - 0.036 14.3 20.3 1.6 9.1 0.2 6.3 4 3 2 6 6 5 0 Tetratricopeptide repeat SpoIIIAH PF12685.7 GAX20186.1 - 0.043 13.6 0.5 0.043 13.6 0.5 1.6 2 0 0 2 2 2 0 SpoIIIAH-like protein HrpB1_HrpK PF09613.10 GAX20186.1 - 0.057 13.1 2.0 0.26 10.9 1.9 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) HemY_N PF07219.13 GAX20186.1 - 0.12 12.6 2.5 16 5.8 0.0 3.7 2 1 2 4 4 4 0 HemY protein N-terminus TPR_4 PF07721.14 GAX20186.1 - 2.5 9.0 4.8 13 6.7 0.2 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat PTR2 PF00854.21 GAX20187.1 - 9.6e-41 139.9 15.4 2.2e-21 76.2 3.0 2.3 2 0 0 2 2 2 2 POT family DUF4490 PF14892.6 GAX20187.1 - 0.018 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) HSF_DNA-bind PF00447.17 GAX20188.1 - 1.6e-16 60.7 0.0 1.6e-16 60.7 0.0 2.0 2 1 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.22 GAX20188.1 - 0.0063 17.0 1.9 0.0097 16.4 0.1 2.1 2 0 0 2 2 2 1 Ets-domain NTF-like PF14540.6 GAX20188.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase-like Ribosomal_S15 PF00312.22 GAX20189.1 - 1.5e-30 105.2 0.5 1.5e-30 105.2 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 polyprenyl_synt PF00348.17 GAX20190.1 - 8.3e-58 195.4 0.0 1.1e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Proteasome PF00227.26 GAX20191.1 - 2.6e-58 196.6 0.1 3.5e-58 196.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX20191.1 - 7.6e-13 47.9 0.0 1.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DEAD PF00270.29 GAX20192.1 - 5e-33 114.3 0.1 3.8e-32 111.5 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX20192.1 - 2.7e-27 95.3 0.0 7.2e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX20192.1 - 0.00014 21.9 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAX20192.1 - 0.0024 18.2 0.5 0.006 16.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATP-grasp_6 PF18419.1 GAX20192.1 - 0.0039 16.8 0.2 0.034 13.8 0.1 2.5 2 0 0 2 2 2 1 ATP-grasp-like domain Peptidase_S41 PF03572.18 GAX20192.1 - 0.0078 15.8 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S41 tRNA-synt_1b PF00579.25 GAX20192.1 - 0.022 14.1 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AAA_30 PF13604.6 GAX20192.1 - 0.1 12.3 0.4 0.45 10.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain DUF1269 PF06897.12 GAX20192.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PKI PF02827.16 GAX20192.1 - 0.23 11.7 0.2 0.23 11.7 0.2 1.9 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor His_Phos_1 PF00300.22 GAX20193.1 - 1.1e-19 70.9 0.2 3.5e-19 69.3 0.0 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 GAX20197.1 - 7.7e-09 35.3 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 GAX20197.1 - 6.5e-07 30.0 0.2 2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 GAX20197.1 - 7.8e-05 22.6 3.7 7.8e-05 22.6 3.7 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 GAX20197.1 - 8e-05 22.4 3.7 8e-05 22.4 3.7 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) REC114-like PF15165.6 GAX20197.1 - 0.0026 17.6 0.5 0.0026 17.6 0.5 1.8 2 0 0 2 2 2 1 Meiotic recombination protein REC114-like zf-CCCH_3 PF15663.5 GAX20197.1 - 0.022 15.0 0.3 0.069 13.4 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger containing family FYVE PF01363.21 GAX20197.1 - 0.043 13.9 1.5 0.067 13.3 0.2 2.0 2 0 0 2 2 2 0 FYVE zinc finger Nup35_RRM_2 PF14605.6 GAX20197.1 - 0.11 12.6 0.1 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 GAX20197.1 - 0.47 10.3 5.7 0.18 11.6 2.5 2.1 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAX20197.1 - 1.9 9.1 6.4 0.33 11.5 2.0 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TauE PF01925.19 GAX20199.1 - 7.6e-23 81.4 44.0 3.4e-11 43.2 18.7 2.7 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE DUF3169 PF11368.8 GAX20199.1 - 0.032 13.7 3.0 0.048 13.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) PRP1_N PF06424.12 GAX20199.1 - 1.6 9.1 7.3 3 8.3 7.3 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Mpp10 PF04006.12 GAX20199.1 - 3.2 6.1 13.2 4.4 5.6 13.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Form_Nir_trans PF01226.17 GAX20200.1 - 2.3e-63 213.7 23.6 2.9e-63 213.4 23.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter LSM PF01423.22 GAX20201.1 - 2e-18 65.8 0.0 2.5e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX20201.1 - 7e-05 22.9 0.0 9.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1826 PF08856.11 GAX20202.1 - 7.6e-14 52.1 0.1 1.8e-13 50.8 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1826) DUF1841 PF08897.11 GAX20202.1 - 0.026 14.5 0.6 2.4 8.2 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1841) AAA_16 PF13191.6 GAX20203.1 - 1.6e-27 96.9 0.0 3.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX20203.1 - 0.00017 21.9 0.0 0.00093 19.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 GAX20203.1 - 0.0023 17.2 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.6 GAX20203.1 - 0.0052 16.8 0.3 3.1 7.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 GAX20203.1 - 0.0058 16.6 0.6 0.1 12.5 0.0 2.7 2 1 0 3 3 3 1 NACHT domain AAA_5 PF07728.14 GAX20203.1 - 0.0066 16.4 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX20203.1 - 0.01 15.0 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 GAX20203.1 - 0.011 15.1 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 GAX20203.1 - 0.042 13.1 0.0 0.067 12.4 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 GAX20203.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAX20203.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AdoHcyase PF05221.17 GAX20204.1 - 1.5e-140 467.5 0.0 1.7e-140 467.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GAX20204.1 - 1.3e-79 266.0 3.7 2e-79 265.3 3.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX20204.1 - 3.9e-09 36.1 0.2 6.9e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAX20204.1 - 1.6e-05 24.6 0.1 2.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 GAX20204.1 - 0.00016 21.0 1.4 0.00072 18.9 1.4 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 GAX20204.1 - 0.00049 20.2 0.2 0.0013 18.8 0.2 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 GAX20204.1 - 0.024 14.9 0.1 0.067 13.5 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 GAX20204.1 - 0.067 13.6 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding RNA_pol_Rpb5_C PF01191.19 GAX20205.1 - 6.4e-34 115.7 0.2 1.1e-33 114.9 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 GAX20205.1 - 1.2e-24 86.7 0.0 2.4e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain LSM PF01423.22 GAX20206.1 - 1.1e-08 34.6 0.1 1.5e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX20206.1 - 0.081 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Keratin_2_head PF16208.5 GAX20206.1 - 0.65 10.1 34.4 0.92 9.6 34.4 1.2 1 0 0 1 1 1 0 Keratin type II head TPR_12 PF13424.6 GAX20207.1 - 2.9e-24 85.2 16.5 1.2e-11 44.7 0.7 4.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX20207.1 - 1.2e-16 59.3 15.2 0.0014 18.5 0.0 6.6 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX20207.1 - 5.5e-13 48.1 9.4 0.0033 17.2 0.2 5.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX20207.1 - 5e-12 45.0 13.7 0.053 13.6 0.1 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20207.1 - 2.3e-10 39.8 5.1 0.0012 18.9 0.1 5.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX20207.1 - 2.7e-10 39.8 15.4 0.014 15.3 0.1 6.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAX20207.1 - 1.5e-07 31.9 1.3 0.32 11.5 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX20207.1 - 5.4e-05 23.6 8.9 0.16 12.6 0.0 5.0 6 0 0 6 6 4 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX20207.1 - 0.00016 21.4 5.0 0.0024 17.6 3.7 2.5 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.6 GAX20207.1 - 0.0002 21.9 8.7 8.4 7.5 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX20207.1 - 0.00079 19.6 3.4 0.38 11.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX20207.1 - 0.0018 18.9 13.7 3.4 8.4 1.4 4.7 4 2 0 4 4 4 3 Tetratricopeptide repeat MIT PF04212.18 GAX20207.1 - 0.0023 18.0 0.1 0.79 9.8 0.0 4.0 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 GAX20207.1 - 0.013 15.7 5.8 0.58 10.4 0.4 3.8 3 1 1 4 4 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAX20207.1 - 0.044 13.5 8.2 39 4.0 0.0 6.4 7 1 1 8 8 7 0 TPR repeat SHNi-TPR PF10516.9 GAX20207.1 - 0.064 12.7 0.1 0.74 9.3 0.0 2.8 3 0 0 3 3 3 0 SHNi-TPR TPR_4 PF07721.14 GAX20207.1 - 0.28 11.9 8.0 91 4.1 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat ABC1 PF03109.16 GAX20208.1 - 1e-21 77.3 0.8 6e-21 74.8 0.0 2.6 3 0 0 3 3 3 1 ABC1 family WaaY PF06176.11 GAX20208.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_M43 PF05572.13 GAX20209.1 - 8.9e-13 48.4 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX20209.1 - 0.00013 22.2 0.1 0.00055 20.1 0.0 2.1 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX20209.1 - 0.0034 17.9 0.0 0.0065 17.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX20209.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX20209.1 - 0.029 14.3 0.4 0.077 12.9 0.0 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX20209.1 - 0.051 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 GAX20209.1 - 0.056 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M43 PF05572.13 GAX20210.1 - 1e-15 58.0 0.0 2.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX20210.1 - 1.8e-06 28.3 0.1 4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX20210.1 - 0.0063 17.0 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX20210.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX20210.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX20210.1 - 0.053 13.4 0.3 0.15 11.9 0.3 1.9 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 GAX20210.1 - 0.11 11.4 0.4 0.2 10.6 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 GAX20210.1 - 0.26 10.5 0.1 0.41 9.8 0.1 1.2 1 0 0 1 1 1 0 Met-zincin AAA PF00004.29 GAX20211.1 - 2e-46 157.7 0.0 2.4e-31 108.9 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX20211.1 - 3.9e-09 37.1 0.0 0.012 16.1 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAX20211.1 - 6e-06 26.3 0.2 0.038 14.0 0.0 3.8 2 2 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 GAX20211.1 - 7.7e-06 25.6 0.2 2e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAX20211.1 - 4.1e-05 23.9 0.0 1.1 9.5 0.0 3.8 2 2 1 4 4 4 1 AAA domain RuvB_N PF05496.12 GAX20211.1 - 0.00027 20.7 0.0 0.22 11.2 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX20211.1 - 0.022 14.9 0.1 12 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAX20211.1 - 0.032 13.8 0.2 12 5.4 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 GAX20211.1 - 0.035 13.8 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX20211.1 - 0.036 13.8 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX20211.1 - 0.037 14.4 0.0 4.9 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 GAX20211.1 - 0.055 13.0 0.1 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAX20211.1 - 0.062 12.7 0.1 4 6.8 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 GAX20211.1 - 0.083 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Rad17 PF03215.15 GAX20211.1 - 0.09 12.7 0.1 12 5.7 0.0 2.7 2 1 1 3 3 3 0 Rad17 P-loop domain IstB_IS21 PF01695.17 GAX20211.1 - 0.091 12.5 0.2 14 5.3 0.1 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.6 GAX20211.1 - 0.15 12.4 0.0 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX20211.1 - 0.19 12.3 0.0 18 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain CBF PF03914.17 GAX20212.1 - 9.2e-26 90.9 2.4 9.2e-26 90.9 2.4 3.3 2 2 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 GAX20212.1 - 0.0078 16.6 0.1 0.032 14.7 0.1 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein ArfGap PF01412.18 GAX20213.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SCHIP-1 PF10148.9 GAX20213.1 - 0.0046 16.6 0.7 0.24 11.0 0.1 2.3 2 0 0 2 2 2 2 Schwannomin-interacting protein 1 IF3_C PF00707.22 GAX20214.1 - 1.2e-09 38.0 1.8 5.1e-08 32.8 0.3 2.9 3 1 1 4 4 4 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 GAX20214.1 - 2.6e-08 34.0 0.0 4.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain cwf18 PF08315.12 GAX20214.1 - 0.05 14.3 2.2 0.069 13.8 2.2 1.4 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor Gemin6 PF06372.12 GAX20214.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Gemin6 protein GPDPase_memb PF10110.9 GAX20217.1 - 0.38 9.5 37.5 24 3.6 37.5 2.6 1 1 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase OST_P2 PF18235.1 GAX20218.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase Peripheral 2 domain Ribosomal_S17 PF00366.20 GAX20221.1 - 8.1e-22 77.1 0.7 1.2e-21 76.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 p450 PF00067.22 GAX20222.1 - 1.3e-06 27.5 0.0 3.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 ARGLU PF15346.6 GAX20222.1 - 0.041 13.8 0.8 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Transcrip_reg PF01709.20 GAX20223.1 - 1.7e-67 227.3 3.6 2.1e-67 227.1 3.6 1.0 1 0 0 1 1 1 1 Transcriptional regulator Thioredoxin_6 PF13848.6 GAX20223.1 - 0.061 13.2 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain BATS PF06968.13 GAX20224.1 - 3.3e-18 65.6 0.3 1.2e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 GAX20224.1 - 3.7e-13 50.2 0.1 5.8e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Peptidase_M24 PF00557.24 GAX20224.1 - 0.0036 17.0 0.1 0.0054 16.4 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 RuvC_III PF18541.1 GAX20224.1 - 0.029 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 RuvC endonuclease subdomain 3 ZYG-11_interact PF05884.12 GAX20224.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 RVT_3 PF13456.6 GAX20225.1 - 1.4e-44 150.9 0.0 6.3e-27 93.8 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like PBP1_TM PF14812.6 GAX20225.1 - 2.2 8.7 5.5 4.6 7.7 0.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3172 PF11371.8 GAX20229.1 - 1.1e-58 196.9 0.3 1.4e-58 196.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) Cpn60_TCP1 PF00118.24 GAX20230.1 - 8e-138 460.1 1.8 9.4e-138 459.9 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZART1 PF12554.8 GAX20230.1 - 0.061 13.1 1.3 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Beta_helix_2 PF18835.1 GAX20230.1 - 0.13 12.0 1.1 3.5 7.5 0.0 3.2 3 0 0 3 3 3 0 Beta helix repeat of Inulin fructotransferase 2-Hacid_dh_C PF02826.19 GAX20232.1 - 2.4e-51 173.6 0.0 5.2e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 GAX20232.1 - 0.00023 21.3 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 GAX20232.1 - 0.0067 16.9 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 XdhC Rossmann domain NAD_binding_2 PF03446.15 GAX20232.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 GAX20232.1 - 0.024 14.3 0.0 0.088 12.5 0.0 2.0 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Exonuc_X-T_C PF08411.10 GAX20232.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal NAD_binding_10 PF13460.6 GAX20232.1 - 0.032 14.1 0.0 0.086 12.7 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding AlaDh_PNT_C PF01262.21 GAX20232.1 - 0.037 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 GAX20232.1 - 0.037 14.8 0.0 0.63 10.9 0.0 2.7 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ELFV_dehydrog PF00208.21 GAX20232.1 - 0.038 13.7 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.17 GAX20232.1 - 0.11 13.1 0.0 0.74 10.4 0.0 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.19 GAX20232.1 - 0.13 11.0 0.0 0.56 8.9 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase MIF4G PF02854.19 GAX20235.1 - 9.5e-31 107.1 8.4 1.6e-21 76.9 7.5 3.6 4 0 0 4 4 4 2 MIF4G domain MA3 PF02847.17 GAX20235.1 - 7e-08 32.5 0.6 4.2e-07 29.9 0.0 2.6 3 0 0 3 3 3 1 MA3 domain VASt PF16016.5 GAX20236.1 - 4.4e-17 62.9 0.0 7.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PGK PF00162.19 GAX20237.1 - 1.7e-155 517.6 0.8 2.1e-155 517.3 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase CAF1C_H4-bd PF12265.8 GAX20238.1 - 7.2e-13 48.6 0.0 1.2e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Peptidase_S10 PF00450.22 GAX20239.1 - 2.2e-80 271.1 0.2 4.8e-80 270.0 0.2 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase NmrA PF05368.13 GAX20240.1 - 1.8e-09 37.5 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAX20240.1 - 4.6e-08 33.2 0.0 1.7e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Amidase PF01425.21 GAX20240.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Amidase Epimerase PF01370.21 GAX20240.1 - 0.098 12.1 0.4 2.2 7.7 0.0 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Lipase_GDSL_2 PF13472.6 GAX20241.1 - 2.6e-08 34.5 0.0 1.2e-07 32.3 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Phage_Gp15 PF06854.11 GAX20241.1 - 0.0014 18.6 0.5 0.0027 17.7 0.2 1.5 2 0 0 2 2 2 1 Bacteriophage Gp15 protein Pyr_redox_2 PF07992.14 GAX20242.1 - 1e-52 179.2 1.2 1.8e-52 178.4 1.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX20242.1 - 1.4e-28 99.3 0.5 2.8e-28 98.4 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX20242.1 - 6.5e-17 61.9 3.6 2.3e-13 50.5 0.0 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX20242.1 - 2.9e-13 49.7 4.8 5e-05 22.6 0.6 3.4 3 0 0 3 3 3 3 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAX20242.1 - 2.7e-11 43.3 2.7 2.9e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX20242.1 - 1.2e-06 28.3 10.9 0.0093 15.6 1.4 3.8 3 1 1 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.17 GAX20242.1 - 3.7e-06 26.4 2.7 5.9e-06 25.7 0.5 2.3 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 GAX20242.1 - 8.9e-06 26.1 0.2 0.00038 20.9 0.0 2.7 3 0 0 3 3 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAX20242.1 - 1.7e-05 24.1 1.0 0.081 12.0 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 GAX20242.1 - 1.8e-05 24.3 5.1 0.002 17.5 0.2 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAX20242.1 - 2.9e-05 23.1 3.4 0.00023 20.1 0.3 2.5 2 1 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 GAX20242.1 - 6.3e-05 23.1 5.5 0.0037 17.5 0.6 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAX20242.1 - 0.00015 21.2 4.4 0.071 12.3 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 GAX20242.1 - 0.00035 19.8 9.4 0.013 14.6 1.1 4.0 4 0 0 4 4 4 2 FAD binding domain AlaDh_PNT_C PF01262.21 GAX20242.1 - 0.00035 19.9 0.5 0.83 8.9 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAX20242.1 - 0.00071 18.4 9.9 0.002 16.9 0.3 3.7 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 GAX20242.1 - 0.011 14.9 1.2 0.18 10.9 0.0 2.7 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 GAX20242.1 - 0.045 13.6 1.1 0.065 13.1 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAX20242.1 - 0.055 13.7 2.8 7 6.9 0.0 3.4 3 1 0 3 3 3 0 TrkA-N domain DFP PF04127.15 GAX20242.1 - 0.074 12.9 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Peptidase_C32 PF05411.12 GAX20242.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase HrpB_C PF08482.10 GAX20242.1 - 0.11 12.9 0.1 13 6.2 0.0 2.4 2 0 0 2 2 2 0 ATP-dependent helicase C-terminal ThiF PF00899.21 GAX20242.1 - 0.13 11.6 0.0 0.38 10.1 0.0 1.7 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.6 GAX20242.1 - 2.4 8.2 5.1 8.8 6.3 0.1 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding FGGY_N PF00370.21 GAX20243.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Sugar_tr PF00083.24 GAX20244.1 - 2e-84 284.1 28.3 2.6e-84 283.7 28.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX20244.1 - 1.4e-27 96.5 61.7 1.4e-24 86.7 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.22 GAX20245.1 - 4.8e-55 185.6 0.0 5.7e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX20245.1 - 1.1e-28 99.9 0.0 1.6e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX20245.1 - 5.2e-12 45.6 0.0 7.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX20245.1 - 0.00048 19.7 0.0 0.0014 18.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAX20245.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAX20245.1 - 0.0073 16.2 0.8 0.43 10.5 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 GAX20245.1 - 0.019 14.7 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 GAX20245.1 - 0.028 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.18 GAX20245.1 - 0.032 14.0 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TniB PF05621.11 GAX20245.1 - 0.049 13.0 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 GAX20245.1 - 0.056 12.9 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAX20245.1 - 0.057 13.8 0.0 0.071 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 GAX20245.1 - 0.21 10.7 0.1 1.1 8.4 0.0 2.1 2 1 1 3 3 3 0 G-protein alpha subunit Pkinase PF00069.25 GAX20246.1 - 8e-42 143.4 0.0 2.6e-29 102.4 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX20246.1 - 6.2e-25 88.0 0.0 2.8e-08 33.4 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Med9 PF07544.13 GAX20246.1 - 0.011 15.8 0.1 0.027 14.6 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 APH PF01636.23 GAX20246.1 - 0.1 12.5 1.8 0.39 10.6 0.1 2.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Flavodoxin_1 PF00258.25 GAX20247.1 - 1.8e-06 28.2 0.0 2.9e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin Pkinase PF00069.25 GAX20248.1 - 1.6e-54 185.0 0.0 2.5e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX20248.1 - 3.6e-32 110.3 0.0 2.9e-18 65.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX20248.1 - 3.2e-22 79.1 0.0 6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX20248.1 - 5e-14 52.5 4.0 4.8e-09 36.5 1.7 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX20248.1 - 6.7e-14 50.3 3.2 0.00021 20.6 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 GAX20248.1 - 5.7e-12 44.5 2.0 0.025 14.5 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 GAX20248.1 - 4e-09 36.2 2.8 0.00079 19.2 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX20248.1 - 1e-06 27.9 3.8 0.00034 20.0 0.3 3.1 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 GAX20248.1 - 7.4e-06 25.5 0.0 3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX20248.1 - 8.5e-06 25.3 0.0 3.7e-05 23.2 0.0 2.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 GAX20248.1 - 0.0035 17.3 0.1 0.0084 16.1 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_4 PF12763.7 GAX20248.1 - 0.037 14.0 1.9 3.1 7.8 0.2 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Fer2 PF00111.27 GAX20249.1 - 0.00064 19.6 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain LEAP-2 PF07359.11 GAX20250.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) PI-PLC-X PF00388.19 GAX20251.1 - 7.7e-50 168.3 0.0 1.8e-49 167.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAX20251.1 - 1.5e-36 125.2 0.0 3.9e-36 123.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 GAX20251.1 - 2.2e-08 34.3 0.0 9.7e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 C2 domain EF-hand_1 PF00036.32 GAX20251.1 - 0.037 13.6 2.1 0.042 13.4 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 GAX20251.1 - 0.051 14.0 0.3 0.36 11.3 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 GAX20251.1 - 0.12 12.4 0.0 0.94 9.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Fe_dep_repr_C PF02742.15 GAX20251.1 - 0.15 12.1 0.1 0.38 10.9 0.1 1.7 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Ank_2 PF12796.7 GAX20252.1 - 6.6e-25 87.5 2.7 1.3e-12 48.2 0.3 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) ACBP PF00887.19 GAX20252.1 - 2.3e-18 66.2 0.5 4.5e-18 65.2 0.5 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 GAX20252.1 - 3.3e-16 59.4 1.7 2.7e-08 34.2 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX20252.1 - 8.7e-14 51.4 0.3 4.5e-10 39.6 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX20252.1 - 1.3e-11 43.6 0.0 0.0012 19.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 GAX20252.1 - 7.6e-11 42.0 2.8 0.00044 20.6 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 GAX20253.1 - 7.6e-21 74.5 0.0 8.1e-06 26.3 0.1 5.3 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX20253.1 - 4.2e-11 43.1 0.1 6.3e-05 23.4 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX20253.1 - 1.6e-09 37.2 4.1 14 6.7 0.0 8.6 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 GAX20253.1 - 2.4e-06 27.7 2.4 4.5 7.7 0.0 5.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX20253.1 - 3e-05 24.3 1.7 1.1 9.8 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat BTB PF00651.31 GAX20253.1 - 0.00077 19.7 0.0 0.0023 18.2 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain DUF3246 PF11596.8 GAX20253.1 - 0.75 9.2 2.7 1.4 8.3 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TPD PF14811.6 GAX20254.1 - 2e-13 50.4 0.1 9.5e-13 48.2 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function TPD sequence-motif HNH_3 PF13392.6 GAX20255.1 - 4.9e-16 58.2 2.9 9e-07 28.6 1.1 2.7 2 0 0 2 2 2 2 HNH endonuclease Acetyltransf_2 PF00797.17 GAX20256.1 - 3.6e-35 121.9 0.0 1.8e-34 119.6 0.0 1.8 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 GAX20256.1 - 0.13 12.7 0.1 0.43 11.0 0.0 1.9 1 1 1 2 2 2 0 Transglutaminase-like superfamily Arg_repressor PF01316.21 GAX20256.1 - 0.14 12.0 0.3 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain G6PD_C PF02781.16 GAX20257.1 - 1e-82 277.6 0.0 1.4e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAX20257.1 - 9.9e-47 159.8 0.0 1.5e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF4512 PF14975.6 GAX20257.1 - 0.099 13.4 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Med6 PF04934.14 GAX20261.1 - 4.7e-24 84.7 0.0 6.7e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component PAS_9 PF13426.7 GAX20262.1 - 2.6e-17 63.0 0.0 5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 GAX20262.1 - 2.4e-07 30.7 11.7 4.5e-07 29.9 11.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX20262.1 - 7.2e-06 26.0 5.6 1.4e-05 25.1 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 GAX20262.1 - 1.4e-05 25.3 0.0 3.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GAX20262.1 - 0.056 13.7 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold Glyco_transf_7C PF02709.14 GAX20262.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase DUF3984 PF13136.6 GAX20262.1 - 0.79 9.1 3.2 0.28 10.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) ASL_C PF08328.11 GAX20263.1 - 0.03 14.4 0.3 0.041 14.0 0.3 1.3 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminal HEPN_SAV_6107 PF18726.1 GAX20263.1 - 0.072 13.6 0.2 0.073 13.6 0.2 1.1 1 0 0 1 1 1 0 SAV_6107-like HEPN Cadherin_C_2 PF16492.5 GAX20263.1 - 0.078 13.7 0.1 0.08 13.7 0.1 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RINT1_TIP1 PF04437.13 GAX20264.1 - 0.0087 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF4290 PF14123.6 GAX20264.1 - 0.021 14.4 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) DUF4771 PF15995.5 GAX20264.1 - 0.17 12.1 2.0 0.2 11.9 0.5 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4771) 2Fe-2S_thioredx PF01257.19 GAX20266.1 - 2.3e-55 186.5 0.4 2.7e-55 186.2 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Nuc_sug_transp PF04142.15 GAX20267.1 - 1.5e-84 283.9 17.5 1.8e-84 283.6 17.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAX20267.1 - 3.4e-15 56.0 16.2 5.4e-15 55.4 16.2 1.4 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 GAX20267.1 - 5.3e-06 25.9 18.0 6.6e-06 25.6 17.7 1.3 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 GAX20267.1 - 3.4e-05 23.0 5.1 3.4e-05 23.0 5.1 2.3 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAX20267.1 - 0.00017 21.7 23.7 0.004 17.3 9.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAX20267.1 - 0.48 9.7 15.7 0.67 9.3 14.2 2.0 1 1 1 2 2 2 0 Triose-phosphate Transporter family DMT_6 PF04342.12 GAX20267.1 - 1.4 9.2 12.4 0.19 12.0 0.6 3.9 2 2 1 4 4 4 0 Putative member of DMT superfamily (DUF486) GTP_EFTU PF00009.27 GAX20268.1 - 1.1e-49 168.7 0.0 3.8e-47 160.3 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX20268.1 - 8.6e-18 64.2 0.0 2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GAX20268.1 - 1.2e-15 57.4 0.0 2.5e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 GAX20268.1 - 3.1e-06 26.9 0.0 5.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 GAX20268.1 - 3.5e-06 27.3 0.1 9.4e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAX20268.1 - 0.00082 19.2 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 GAX20268.1 - 0.0031 18.0 0.0 0.065 13.7 0.0 2.5 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain Imm53 PF15580.6 GAX20268.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 53 SRPRB PF09439.10 GAX20268.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NOG1_N PF17835.1 GAX20269.1 - 3.8e-52 176.5 2.9 4.8e-52 176.2 0.1 2.3 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 GAX20269.1 - 1.4e-26 92.0 0.5 2.9e-26 91.0 0.5 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 GAX20269.1 - 2.6e-24 84.9 2.8 5.5e-24 83.9 2.8 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 GAX20269.1 - 4.7e-17 62.1 0.0 3.4e-16 59.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX20269.1 - 8.4e-09 35.1 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 GAX20269.1 - 0.0017 17.7 0.0 0.0048 16.3 0.0 1.8 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 GAX20269.1 - 0.0065 16.1 0.0 0.015 14.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAX20269.1 - 0.078 13.2 0.1 0.86 9.8 0.1 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAX20269.1 - 0.081 12.8 0.8 2.1 8.2 0.1 3.0 2 1 0 2 2 2 0 RsgA GTPase CTP_transf_like PF01467.26 GAX20271.1 - 4.7e-36 124.1 0.0 6.5e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 GAX20271.1 - 0.0091 15.9 0.2 3.2 7.6 0.1 3.3 2 1 0 2 2 2 2 FAD synthetase EutQ PF06249.12 GAX20271.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cyt-b5 PF00173.28 GAX20272.1 - 1.8e-07 31.2 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1682 PF07946.14 GAX20272.1 - 3.9 6.6 19.1 12 4.9 18.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) TPD PF14811.6 GAX20273.1 - 9.9e-37 125.8 0.0 1.8e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif DUF4268 PF14088.6 GAX20274.1 - 0.014 15.3 0.1 0.86 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) Kinesin PF00225.23 GAX20275.1 - 1e-85 287.6 0.8 1e-85 287.6 0.8 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX20275.1 - 1.2e-13 51.3 0.1 2.5e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding RNA_pol_3_Rpc31 PF11705.8 GAX20275.1 - 0.0029 17.9 3.6 0.0086 16.4 3.6 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 AAA_16 PF13191.6 GAX20275.1 - 0.038 14.4 0.1 0.13 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 GAX20275.1 - 0.046 13.2 0.1 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4559 PF15112.6 GAX20275.1 - 0.98 9.0 4.7 1.9 8.1 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF87 PF01935.17 GAX20275.1 - 1.8 8.6 4.3 3.4 7.7 2.7 2.5 1 1 1 2 2 2 0 Helicase HerA, central domain Dcc1 PF09724.9 GAX20276.1 - 2.7e-31 109.1 0.1 3.3e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 UAA PF08449.11 GAX20277.1 - 3.6e-55 187.3 23.3 5.8e-55 186.6 23.3 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX20277.1 - 6.8e-07 29.5 12.7 6.8e-07 29.5 12.7 3.1 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 GAX20277.1 - 0.17 11.2 19.2 0.066 12.6 16.3 1.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family Herpes_gE PF02480.16 GAX20277.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3727 PF12527.8 GAX20278.1 - 8.2e-08 32.4 17.1 0.0093 16.2 4.2 4.9 2 2 1 3 3 3 3 Protein of unknown function (DUF3727) Dynamin_N PF00350.23 GAX20278.1 - 0.15 12.1 1.0 0.44 10.6 1.0 1.8 1 1 0 1 1 1 0 Dynamin family ERp29 PF07749.12 GAX20278.1 - 0.36 11.8 3.1 37 5.3 0.2 3.4 4 0 0 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain PYC_OADA PF02436.18 GAX20279.1 - 0.01 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Conserved carboxylase domain RRM_1 PF00076.22 GAX20280.1 - 4.2e-08 32.9 0.0 0.0029 17.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF_2 PF14237.6 GAX20280.1 - 0.0013 18.5 0.1 0.0083 15.9 0.0 2.4 2 0 0 2 2 2 1 GYF domain 2 RRM_7 PF16367.5 GAX20280.1 - 0.023 14.8 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif DUF4523 PF15023.6 GAX20280.1 - 0.13 12.1 1.8 2 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Chorismate_bind PF00425.18 GAX20281.1 - 0.075 12.6 0.8 0.081 12.5 0.8 1.1 1 0 0 1 1 1 0 chorismate binding enzyme DUF3299 PF11736.8 GAX20281.1 - 0.19 11.7 0.5 0.22 11.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) DUF1206 PF06724.11 GAX20281.1 - 0.27 11.4 3.1 0.48 10.5 0.8 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) AAA_25 PF13481.6 GAX20282.1 - 4e-06 26.5 0.1 0.0021 17.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAX20282.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX20282.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAX20282.1 - 0.025 13.9 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_35 PF14516.6 GAX20282.1 - 0.17 10.7 0.0 0.36 9.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain HSF_DNA-bind PF00447.17 GAX20283.1 - 1.1e-16 61.2 0.0 3.1e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding RapA_C PF12137.8 GAX20283.1 - 0.0055 15.8 1.4 0.0079 15.2 1.4 1.2 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal GreA_GreB_N PF03449.15 GAX20283.1 - 0.14 12.3 0.1 0.5 10.6 0.1 1.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal TFIIA PF03153.13 GAX20283.1 - 8.4 6.3 13.2 13 5.6 13.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_13 PF13880.6 GAX20284.1 - 3.8e-22 78.0 0.0 8.5e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 GAX20284.1 - 1.6e-13 50.2 1.6 3.4e-13 49.2 1.6 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 GAX20284.1 - 1.6e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX20284.1 - 2.3e-05 24.7 0.0 4.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX20284.1 - 0.024 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 GAX20284.1 - 0.041 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX20284.1 - 0.058 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 GAX20284.1 - 0.066 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RhoGAP PF00620.27 GAX20286.1 - 2.9e-17 62.9 0.0 4.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 GAX20286.1 - 1.3e-09 37.9 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3638 PF12340.8 GAX20287.1 - 6.4e-24 84.5 0.1 2.2e-21 76.2 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 GAX20287.1 - 3.7e-13 48.6 0.1 9.4e-13 47.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.6 GAX20287.1 - 2.4e-11 43.9 2.2 8.6e-09 35.7 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX20287.1 - 1e-09 37.2 4.8 0.0003 20.1 0.2 4.4 4 0 0 4 4 4 2 EF hand Vps62 PF06101.11 GAX20287.1 - 7.1e-08 31.2 0.0 1.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 EF-hand_5 PF13202.6 GAX20287.1 - 8.1e-06 25.1 5.2 0.022 14.3 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GAX20287.1 - 1.4e-05 24.6 8.7 0.025 14.5 0.2 4.4 5 0 0 5 5 4 2 EF-hand domain SH3_9 PF14604.6 GAX20287.1 - 0.00033 20.5 0.1 0.001 18.9 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAX20287.1 - 0.004 16.8 0.1 0.0093 15.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAX20287.1 - 0.0054 16.3 0.4 0.015 14.9 0.4 1.8 1 0 0 1 1 1 1 SH3 domain DUF5563 PF17718.1 GAX20287.1 - 0.17 11.4 0.5 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5563) EF-hand_8 PF13833.6 GAX20287.1 - 0.57 10.1 5.6 1.2 9.1 0.9 3.2 3 1 1 4 4 3 0 EF-hand domain pair RR_TM4-6 PF06459.12 GAX20287.1 - 5.7 6.7 15.0 0.62 9.8 8.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 GAX20287.1 - 6.7 4.7 18.7 11 4.0 18.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GAX20287.1 - 9.2 4.3 25.3 1.1 7.4 17.7 2.4 3 0 0 3 3 3 0 Nop14-like family Kelch_5 PF13854.6 GAX20288.1 - 1.2e-10 41.1 7.0 0.004 17.1 0.2 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 GAX20288.1 - 1.1e-08 34.9 15.4 0.27 11.3 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GAX20288.1 - 6e-06 26.0 9.6 3.8 7.7 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 GAX20288.1 - 2.7e-05 24.3 19.2 0.24 11.8 0.0 7.3 7 0 0 7 7 7 2 Galactose oxidase, central domain F-box PF00646.33 GAX20288.1 - 0.0046 16.8 0.1 0.0089 15.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAX20288.1 - 0.12 12.3 0.5 0.28 11.1 0.5 1.7 1 0 0 1 1 1 0 F-box-like Kelch_1 PF01344.25 GAX20288.1 - 0.6 9.7 9.5 14 5.4 0.2 5.0 5 0 0 5 5 5 0 Kelch motif TPR_12 PF13424.6 GAX20290.1 - 5.6e-07 29.8 0.4 0.061 13.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX20290.1 - 1.2e-06 28.1 0.4 0.15 12.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX20290.1 - 4.2e-06 26.3 0.2 0.32 10.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX20290.1 - 6.6e-06 25.8 0.8 0.11 12.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX20290.1 - 0.0027 17.5 0.8 0.92 9.5 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX20290.1 - 0.0033 18.1 0.7 2.9 9.0 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20290.1 - 0.18 12.1 0.2 18 5.9 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Paf1 PF03985.13 GAX20291.1 - 6.9e-31 107.7 7.5 6.9e-31 107.7 7.5 3.4 2 1 0 2 2 2 1 Paf1 Lsr2 PF11774.8 GAX20291.1 - 1.7 8.8 8.9 0.074 13.2 1.6 2.4 2 0 0 2 2 2 0 Lsr2 FUSC PF04632.12 GAX20291.1 - 4.3 5.8 6.3 7.1 5.0 6.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 GAX20291.1 - 6.3 6.9 11.5 0.76 9.9 2.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Patatin PF01734.22 GAX20292.1 - 4e-08 33.7 0.3 2.3e-07 31.2 0.3 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Myco_arth_vir_N PF09610.10 GAX20292.1 - 2.3 8.4 3.9 3.8 7.7 3.9 1.3 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) ABC_tran PF00005.27 GAX20293.1 - 1.6e-15 57.9 0.4 1.7e-14 54.5 0.4 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAX20293.1 - 3.3e-11 43.6 5.3 4.3e-06 26.7 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX20293.1 - 0.00033 20.3 0.1 0.00081 19.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 GAX20293.1 - 0.0012 18.3 0.2 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 GAX20293.1 - 0.011 15.4 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAX20293.1 - 0.013 15.7 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 GAX20293.1 - 0.023 14.4 0.1 0.045 13.5 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 GAX20293.1 - 0.041 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 GAX20293.1 - 0.049 14.0 0.2 0.084 13.2 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 GAX20293.1 - 0.051 14.1 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX20293.1 - 0.053 13.4 0.3 0.22 11.4 0.0 2.1 2 1 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 GAX20293.1 - 0.057 13.7 0.6 0.32 11.2 0.6 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAX20293.1 - 0.079 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase CLP1_P PF16575.5 GAX20293.1 - 0.12 12.2 0.0 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CNOT11 PF10155.9 GAX20294.1 - 4.4e-47 159.3 2.3 5e-47 159.2 1.2 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Fanconi_A_N PF15865.5 GAX20294.1 - 0.056 12.8 0.4 0.13 11.6 0.4 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus MarR_2 PF12802.7 GAX20294.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 MarR family zf-C3HC PF07967.13 GAX20295.1 - 2.7e-18 66.3 0.1 1.4e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 GAX20295.1 - 0.012 15.8 2.6 0.14 12.3 0.2 2.7 2 1 0 2 2 2 0 Rsm1-like Rootletin PF15035.6 GAX20295.1 - 0.029 14.4 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4050 PF13259.6 GAX20296.1 - 0.00034 21.0 3.7 0.028 14.8 1.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) FAD_binding_3 PF01494.19 GAX20298.1 - 2.7e-22 79.5 0.0 3.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAX20298.1 - 6e-08 33.1 0.3 0.00048 20.6 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAX20298.1 - 8.8e-08 31.7 0.1 0.0024 17.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX20298.1 - 0.0012 19.1 0.1 0.0033 17.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAX20298.1 - 0.0086 15.0 0.1 0.016 14.1 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 GAX20298.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX20298.1 - 0.026 13.6 0.4 0.055 12.5 0.4 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAX20298.1 - 0.044 13.0 0.0 8.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAX20298.1 - 0.12 11.5 0.0 0.29 10.1 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 GAX20298.1 - 0.12 11.4 0.2 0.23 10.5 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAX20298.1 - 0.13 10.9 0.4 0.3 9.7 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 GAX20298.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Phage_tail_APC PF16778.5 GAX20298.1 - 0.35 10.8 1.1 1.5 8.7 1.1 2.1 1 1 0 1 1 1 0 Phage tail assembly chaperone protein DOT1 PF08123.13 GAX20299.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 GAX20299.1 - 0.14 12.8 0.0 0.76 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Trypsin PF00089.26 GAX20300.1 - 3e-22 79.5 0.0 5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin Mnd1 PF03962.15 GAX20301.1 - 5.8e-17 61.7 0.0 1.4e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 GAX20301.1 - 9.3e-17 60.9 0.2 2.8e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DUF919 PF06034.11 GAX20301.1 - 0.00036 20.3 3.1 0.00048 19.9 1.2 2.1 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF919) T3SS_needle_F PF09392.10 GAX20301.1 - 0.0053 16.9 0.6 0.03 14.5 0.6 2.2 1 1 0 1 1 1 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF GATase_4 PF13230.6 GAX20302.1 - 1.2e-19 70.3 0.5 6.7e-14 51.4 0.8 3.4 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAX20302.1 - 5.6e-13 49.2 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX20302.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Lipase_GDSL_2 PF13472.6 GAX20303.1 - 3.2e-17 63.5 0.0 4.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX20303.1 - 2.2e-09 37.6 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1358 PF07096.11 GAX20303.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) DUF4050 PF13259.6 GAX20304.1 - 0.00041 20.7 4.1 0.0022 18.4 1.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) LRR_1 PF00560.33 GAX20305.1 - 0.039 14.5 1.0 3.8e+02 2.4 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 GAX20305.1 - 0.074 13.5 14.9 0.21 12.1 0.3 4.7 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) RSN1_7TM PF02714.15 GAX20305.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate LRR_8 PF13855.6 GAX20305.1 - 0.34 10.7 10.3 0.25 11.1 3.3 3.5 2 1 1 4 4 4 0 Leucine rich repeat Peptidase_S8 PF00082.22 GAX20306.1 - 2.8e-43 148.3 6.9 4.8e-43 147.5 6.9 1.3 1 0 0 1 1 1 1 Subtilase family Phage_r1t_holin PF16945.5 GAX20306.1 - 0.009 16.2 0.9 0.45 10.7 0.0 2.8 2 0 0 2 2 2 1 Putative lactococcus lactis phage r1t holin FeS_assembly_P PF01883.19 GAX20307.1 - 5.5e-09 36.1 0.0 1.3e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Acid_PPase PF12689.7 GAX20307.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Peptidase_S8 PF00082.22 GAX20308.1 - 9.6e-39 133.4 6.4 4.9e-38 131.1 6.4 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAX20308.1 - 0.049 14.3 0.0 0.098 13.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I9 PT PF04886.12 GAX20309.1 - 0.0016 18.0 6.9 0.0016 18.0 6.9 3.8 1 1 1 2 2 2 1 PT repeat Dickkopf_N PF04706.12 GAX20309.1 - 0.021 15.3 7.5 0.025 15.1 5.5 2.0 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Trypsin PF00089.26 GAX20310.1 - 7.4e-34 117.5 0.0 1.1e-33 116.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1087 PF06465.13 GAX20310.1 - 0.073 13.1 0.4 0.29 11.2 0.4 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) DUF1986 PF09342.11 GAX20310.1 - 0.19 12.1 0.0 0.56 10.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Mpv17_PMP22 PF04117.12 GAX20311.1 - 3.3e-15 56.1 0.2 5.8e-15 55.3 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ABC_tran PF00005.27 GAX20312.1 - 2.5e-25 89.6 0.0 4.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAX20312.1 - 2.1e-11 43.7 19.2 3e-11 43.2 19.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GAX20312.1 - 3.2e-07 30.5 0.1 0.00029 20.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX20312.1 - 0.0011 18.4 0.1 0.05 13.0 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 GAX20312.1 - 0.003 17.3 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 GAX20312.1 - 0.0035 17.9 0.2 0.0065 17.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAX20312.1 - 0.0048 16.8 0.2 0.013 15.4 0.2 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAX20312.1 - 0.023 15.0 0.1 0.064 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX20312.1 - 0.034 14.5 0.0 0.08 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GAX20312.1 - 0.054 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAX20312.1 - 0.17 11.4 0.8 0.35 10.4 0.2 1.8 2 0 0 2 2 2 0 AAA domain RR_TM4-6 PF06459.12 GAX20313.1 - 2.4 7.9 6.6 3 7.6 6.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TERB2 PF15101.6 GAX20313.1 - 2.9 7.9 5.6 2.5 8.1 4.5 1.3 1 1 0 1 1 1 0 Telomere-associated protein TERB2 Ada3 PF10198.9 GAX20313.1 - 5 7.3 12.9 8.5 6.5 13.0 1.4 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 Peptidase_M43 PF05572.13 GAX20314.1 - 2.4e-14 53.5 0.0 4.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX20314.1 - 3.2e-05 24.5 0.1 7e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX20314.1 - 0.00039 20.6 2.3 0.00041 20.6 0.9 1.7 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX20314.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Herpes_capsid PF06112.11 GAX20314.1 - 0.045 13.8 1.1 0.074 13.1 1.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Folate_rec PF03024.14 GAX20315.1 - 2.3e-34 118.7 7.4 3.4e-28 98.7 7.0 2.1 2 0 0 2 2 2 2 Folate receptor family HSF_DNA-bind PF00447.17 GAX20316.1 - 2.8e-11 43.9 0.0 5.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Peptidase_M43 PF05572.13 GAX20317.1 - 5.4e-14 52.4 1.4 1e-13 51.5 0.0 2.2 2 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX20317.1 - 4.5e-05 23.7 0.1 4.5e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX20317.1 - 0.00064 20.2 0.1 0.0013 19.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX20317.1 - 0.028 14.1 0.1 0.054 13.1 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Folate_rec PF03024.14 GAX20318.1 - 6.4e-38 130.3 10.6 5.7e-32 110.9 9.5 2.1 2 0 0 2 2 2 2 Folate receptor family NPC1_N PF16414.5 GAX20318.1 - 0.004 16.7 2.7 0.0057 16.3 2.7 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus DUF3177 PF11375.8 GAX20318.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Sigma70_r2 PF04542.14 GAX20319.1 - 3.8e-08 33.0 0.6 1.4e-07 31.1 0.2 2.2 2 1 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 GAX20319.1 - 0.00082 19.4 0.1 0.002 18.2 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 GAX20319.1 - 0.0012 18.4 0.4 0.0052 16.3 0.2 2.3 2 1 0 2 2 2 1 Sigma-70, region 4 BCOR PF15808.5 GAX20319.1 - 0.048 13.9 1.6 0.075 13.2 1.6 1.3 1 0 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region Sigma70_r1_2 PF00140.20 GAX20319.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Sigma70_r4_2 PF08281.12 GAX20319.1 - 0.12 12.1 0.0 0.77 9.5 0.0 2.2 1 1 0 1 1 1 0 Sigma-70, region 4 Guanylate_cyc PF00211.20 GAX20320.1 - 2.9e-41 141.1 0.0 5.3e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX20320.1 - 2.7e-32 112.4 2.2 2.7e-32 112.4 2.2 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 GAX20320.1 - 4.3e-06 26.8 0.0 8.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 CHASE domain RPA PF10134.9 GAX20320.1 - 0.06 12.8 0.5 7.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Replication initiator protein A Claudin_3 PF06653.11 GAX20320.1 - 0.066 13.1 1.1 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Sigma_reg_N PF13800.6 GAX20320.1 - 0.36 11.1 1.3 10 6.5 0.0 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CSS-motif PF12792.7 GAX20321.1 - 0.11 11.9 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 CSS motif domain associated with EAL PDEase_I PF00233.19 GAX20322.1 - 2.9e-18 66.5 0.7 5.1e-18 65.7 0.7 1.3 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mei5_like PF17021.5 GAX20322.1 - 0.0038 17.3 0.3 0.0076 16.3 0.3 1.5 1 0 0 1 1 1 1 Putative double-strand recombination repair-like PDEase_I PF00233.19 GAX20323.1 - 3.2e-18 66.3 0.4 5.8e-18 65.5 0.4 1.3 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mei5_like PF17021.5 GAX20323.1 - 0.0034 17.4 0.2 0.0061 16.6 0.2 1.4 1 0 0 1 1 1 1 Putative double-strand recombination repair-like Hint PF01079.20 GAX20324.1 - 9.7e-16 57.9 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Hint module RNB PF00773.19 GAX20325.1 - 2e-23 83.2 0.0 3.8e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 RNB domain Multi_Drug_Res PF00893.19 GAX20326.1 - 3.8e-12 46.7 5.1 4.9e-12 46.4 5.1 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein Condensin2nSMC PF12422.8 GAX20327.1 - 1.3e-29 103.3 0.2 6.5e-29 101.0 0.2 2.3 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit Adaptin_N PF01602.20 GAX20327.1 - 1.9e-05 23.5 2.4 0.00017 20.3 0.8 2.9 3 0 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.22 GAX20327.1 - 0.00013 21.9 5.0 3.4 8.2 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 GAX20327.1 - 0.00098 19.6 4.4 0.039 14.5 0.5 4.2 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 GAX20327.1 - 0.0017 18.5 3.3 1.8 8.6 0.0 4.2 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 COX5B PF01215.19 GAX20328.1 - 1.1e-05 25.1 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF3984 PF13136.6 GAX20328.1 - 0.23 10.8 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) NAC PF01849.18 GAX20328.1 - 3.2 7.8 5.1 0.88 9.6 0.1 2.5 4 0 0 4 4 4 0 NAC domain Proteasome PF00227.26 GAX20330.1 - 9.4e-24 84.0 0.0 1.1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Thioredoxin PF00085.20 GAX20331.1 - 3e-27 94.6 0.1 3.6e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAX20331.1 - 0.00043 19.7 0.0 0.00045 19.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAX20331.1 - 0.00054 20.4 0.1 0.003 18.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX20331.1 - 0.0073 16.5 0.1 0.015 15.5 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX20331.1 - 0.0076 16.0 0.0 0.0085 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 GAX20331.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 AhpC-TSA PF00578.21 GAX20331.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 GAX20331.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like FKBP_N PF01346.18 GAX20332.1 - 0.017 16.0 0.0 0.035 15.1 0.0 1.5 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2083 PF09856.9 GAX20332.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Cupin_7 PF12973.7 GAX20333.1 - 1.4e-06 28.1 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 2 ChrR Cupin-like domain Cupin_2 PF07883.11 GAX20333.1 - 0.0012 18.6 0.0 0.0056 16.4 0.0 2.0 2 0 0 2 2 2 1 Cupin domain 7tm_1 PF00001.21 GAX20336.1 - 0.004 16.5 17.7 0.004 16.5 17.7 2.0 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF4064 PF13273.6 GAX20336.1 - 2.5 8.4 14.1 19 5.6 8.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DEAD PF00270.29 GAX20337.1 - 1.4e-49 168.2 0.0 2.3e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX20337.1 - 1.7e-32 112.0 0.0 8.9e-32 109.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX20337.1 - 0.00034 20.7 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX20337.1 - 0.063 12.5 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 GAX20337.1 - 0.25 10.1 0.0 0.77 8.5 0.0 1.8 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 GAX20337.1 - 0.27 10.6 0.0 0.54 9.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Globin PF00042.22 GAX20338.1 - 8.9e-13 48.8 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Globin Folate_rec PF03024.14 GAX20339.1 - 7.7e-36 123.5 16.2 7.3e-31 107.3 15.5 2.1 2 0 0 2 2 2 2 Folate receptor family NPC1_N PF16414.5 GAX20339.1 - 0.005 16.4 5.0 0.0071 15.9 5.0 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus SAGA-Tad1 PF12767.7 GAX20340.1 - 0.12 12.1 0.1 0.12 12.1 0.1 7.7 4 3 0 4 4 4 0 Transcriptional regulator of RNA polII, SAGA, subunit ELO PF01151.18 GAX20341.1 - 1e-54 185.8 30.1 1.2e-54 185.5 30.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RAMP4 PF06624.12 GAX20341.1 - 0.095 12.8 0.5 0.28 11.3 0.5 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Peptidase_M24 PF00557.24 GAX20342.1 - 1.2e-44 152.5 0.2 1.6e-44 152.1 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 GAX20342.1 - 7.3e-16 58.2 5.2 2e-15 56.8 5.2 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GAX20342.1 - 0.7 10.0 10.1 0.19 11.9 4.9 2.6 2 0 0 2 2 2 0 MYND finger DUF3565 PF12088.8 GAX20342.1 - 7.1 6.7 8.8 1.3 9.0 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3565) Peptidase_S28 PF05577.12 GAX20343.1 - 1.5e-56 192.1 0.0 1.9e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Mito_carr PF00153.27 GAX20344.1 - 3.1e-58 193.7 5.4 1.1e-18 67.0 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 GAX20346.1 - 1.4e-30 106.7 1.2 3.1e-30 105.5 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX20346.1 - 3.7e-15 56.3 4.2 3.7e-15 56.3 4.2 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase AgrD PF05931.11 GAX20347.1 - 0.056 13.5 0.5 0.31 11.1 0.1 2.3 2 0 0 2 2 2 0 Staphylococcal AgrD protein GMC_oxred_N PF00732.19 GAX20348.1 - 8.7e-32 110.7 0.0 4.1e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 GAX20348.1 - 5.4e-29 101.6 0.0 9.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAX20348.1 - 8.2e-06 26.0 0.4 6.9e-05 23.0 0.5 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX20348.1 - 0.00016 20.9 0.0 0.0045 16.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FYTT PF07078.11 GAX20348.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Forty-two-three protein HI0933_like PF03486.14 GAX20348.1 - 0.0037 16.0 0.0 0.0067 15.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAX20348.1 - 0.0064 15.8 0.0 0.025 13.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX20348.1 - 0.0066 15.6 0.2 0.13 11.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.16 GAX20348.1 - 0.0085 15.8 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 GAX20348.1 - 0.014 15.0 0.4 0.15 11.6 0.2 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX20348.1 - 0.04 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAX20348.1 - 0.042 13.1 0.0 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 GAX20349.1 - 1.8e-41 141.9 0.0 2.7e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 GAX20349.1 - 0.00027 19.8 0.0 0.041 12.6 0.0 2.5 3 0 0 3 3 3 2 SNF2 family N-terminal domain ResIII PF04851.15 GAX20349.1 - 0.00042 20.4 0.0 0.00073 19.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAX20349.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit GUCT PF08152.12 GAX20350.1 - 2.2e-09 37.5 0.3 3.8e-09 36.7 0.3 1.3 1 0 0 1 1 1 1 GUCT (NUC152) domain zf-C3HC4 PF00097.25 GAX20351.1 - 2.3e-09 37.0 1.1 6.6e-09 35.5 0.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX20351.1 - 2.6e-09 36.9 1.6 2.6e-09 36.9 1.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAX20351.1 - 1.3e-07 31.3 2.6 1.3e-07 31.3 2.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX20351.1 - 1.6e-07 31.2 2.5 1.6e-07 31.2 2.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX20351.1 - 1.6e-06 28.3 9.6 2.6e-05 24.5 9.6 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAX20351.1 - 1.7e-05 24.6 11.7 3.8e-05 23.4 9.3 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAX20351.1 - 5.3e-05 23.3 4.3 5.3e-05 23.3 4.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAX20351.1 - 0.0051 17.1 5.0 0.022 15.1 5.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAX20351.1 - 0.023 14.6 2.4 0.023 14.6 2.4 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 IBR PF01485.21 GAX20351.1 - 0.92 9.8 9.2 9.4 6.5 4.6 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DUF1658 PF07871.11 GAX20351.1 - 3.7 7.7 5.4 9.2 6.4 5.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1658) UCH PF00443.29 GAX20352.1 - 1.8e-42 145.6 0.1 3.4e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX20352.1 - 6.8e-21 75.2 5.9 9.4e-21 74.7 1.3 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAX20352.1 - 3e-07 30.7 9.4 3e-07 30.7 9.4 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein RPE65 PF03055.15 GAX20353.1 - 3.9e-68 230.7 0.0 4.8e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein ACPS PF01648.20 GAX20354.1 - 1.5e-14 54.1 0.0 2.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 GAX20354.1 - 6.5e-08 32.6 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain Solute_trans_a PF03619.16 GAX20355.1 - 2.2e-83 279.8 16.3 3e-83 279.4 16.3 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF423 PF04241.15 GAX20355.1 - 0.2 11.9 3.7 0.22 11.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF423) SLAC1 PF03595.17 GAX20355.1 - 3.3 6.9 13.7 0.65 9.2 3.2 2.4 2 1 0 2 2 2 0 Voltage-dependent anion channel DOT1 PF08123.13 GAX20356.1 - 3.3e-07 30.1 0.0 3.1e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 GAX20356.1 - 0.00034 21.3 0.0 0.00055 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX20356.1 - 0.00053 19.8 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX20356.1 - 0.00091 19.8 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAX20356.1 - 0.0015 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 GAX20356.1 - 0.0041 16.6 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 GAX20356.1 - 0.032 14.1 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cupin_8 PF13621.6 GAX20357.1 - 5.2e-20 72.2 1.4 7.6e-18 65.1 0.7 2.1 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 GAX20357.1 - 7.5e-09 36.0 0.7 3.8e-08 33.7 0.3 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 GAX20357.1 - 1.2e-05 25.0 0.0 3.4e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 GAX20357.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Bap31 PF05529.12 GAX20357.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Cupin_1 PF00190.22 GAX20357.1 - 0.17 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.6 GAX20358.1 - 6.3e-20 72.0 0.7 4e-17 62.8 0.4 2.1 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 GAX20358.1 - 1.3e-08 35.2 0.3 3.8e-08 33.8 0.3 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 GAX20358.1 - 0.00023 20.8 0.1 0.00099 18.8 0.0 2.0 3 0 0 3 3 3 1 Cupin domain Cupin_4 PF08007.12 GAX20358.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein TPMT PF05724.11 GAX20359.1 - 1.1e-42 146.2 0.2 1.4e-42 145.8 0.2 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 GAX20359.1 - 1.6e-07 32.0 0.0 2.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX20359.1 - 3.5e-07 30.1 0.1 7.9e-07 29.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20359.1 - 4.1e-06 27.4 0.0 1.1e-05 26.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX20359.1 - 0.00021 21.9 0.0 0.00043 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF1765 PF08578.10 GAX20359.1 - 0.013 15.9 0.1 0.025 15.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) Methyltransf_31 PF13847.6 GAX20360.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20360.1 - 0.057 14.1 0.0 0.13 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX20360.1 - 0.067 13.9 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DX PF01666.17 GAX20362.1 - 0.0087 16.5 9.5 0.054 14.0 1.9 2.4 2 0 0 2 2 2 2 DX module HMG_box PF00505.19 GAX20364.1 - 1.4e-11 44.6 12.4 4.6e-07 30.2 8.2 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX20364.1 - 3.1e-09 37.3 11.7 9.7e-08 32.5 11.7 2.4 1 1 0 1 1 1 1 HMG-box domain Patatin PF01734.22 GAX20365.1 - 2.6e-09 37.5 0.0 1.5e-07 31.8 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase ADH_N PF08240.12 GAX20366.1 - 3.9e-26 91.1 5.3 6.8e-26 90.3 5.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAX20366.1 - 1.8e-19 70.0 0.2 3.2e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAX20366.1 - 4.7e-06 26.1 0.2 7.7e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAX20366.1 - 0.0001 21.7 1.1 0.00016 21.1 1.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 GAX20366.1 - 0.00018 22.5 0.1 0.00086 20.4 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 GAX20366.1 - 0.00037 20.6 0.1 0.00066 19.8 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX20366.1 - 0.00093 19.5 0.2 0.0071 16.6 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 GAX20366.1 - 0.00094 18.7 0.3 0.0016 18.0 0.3 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_2 PF03446.15 GAX20366.1 - 0.012 15.8 1.2 0.029 14.5 0.6 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAX20366.1 - 0.13 12.9 0.2 0.26 11.9 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CAP_GLY PF01302.25 GAX20367.1 - 4.9e-16 58.5 3.4 7.8e-16 57.9 3.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 GAX20367.1 - 0.00058 20.3 0.0 0.0014 19.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain CoA_binding PF02629.19 GAX20368.1 - 7.4e-33 113.1 0.3 1.5e-32 112.1 0.3 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 GAX20368.1 - 1.7e-22 79.9 0.0 3.2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GAX20368.1 - 1.6e-07 31.2 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAX20368.1 - 7.3e-06 26.5 0.1 1.9e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Glyco_tran_WecB PF03808.13 GAX20368.1 - 0.072 13.0 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family GFO_IDH_MocA PF01408.22 GAX20368.1 - 0.093 13.6 0.0 0.22 12.4 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Jak1_Phl PF17887.1 GAX20369.1 - 0.0063 16.5 9.5 0.27 11.2 0.6 2.1 1 1 1 2 2 2 2 Jak1 pleckstrin homology-like domain EssA PF10661.9 GAX20369.1 - 0.19 11.6 14.4 0.057 13.3 2.0 2.2 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DUF3930 PF13067.6 GAX20369.1 - 0.33 11.3 3.6 51 4.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3930) Atg14 PF10186.9 GAX20369.1 - 0.34 9.9 13.3 0.39 9.7 13.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Usp PF00582.26 GAX20369.1 - 0.59 10.7 5.7 0.1 13.1 0.9 1.8 1 1 1 2 2 2 0 Universal stress protein family Duffy_binding PF05424.11 GAX20369.1 - 9.5 6.2 15.2 2.7 8.0 4.1 2.2 1 1 1 2 2 2 0 Duffy binding domain PP2C PF00481.21 GAX20370.1 - 6.6e-55 186.5 0.0 9.4e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX20370.1 - 3.3e-06 26.9 0.0 1.3e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3209 PF11483.8 GAX20370.1 - 0.087 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Heme_oxygenase PF01126.20 GAX20371.1 - 2.9e-60 203.6 0.2 6.1e-60 202.5 0.2 1.6 1 0 0 1 1 1 1 Heme oxygenase HNF-1B_C PF04812.13 GAX20371.1 - 0.067 13.0 2.0 0.93 9.3 0.7 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Peptidase_M18 PF02127.15 GAX20372.1 - 1.7e-153 511.5 0.0 2e-153 511.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAX20372.1 - 6.4e-05 22.1 0.1 0.028 13.4 0.2 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase TetR_C_12 PF16914.5 GAX20372.1 - 0.17 12.0 0.3 0.92 9.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal RAP80_UIM PF18282.1 GAX20373.1 - 0.81 9.5 8.4 1.3 8.8 7.9 1.7 1 1 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Cu2_monoox_C PF03712.15 GAX20374.1 - 2.1e-18 66.3 0.0 3.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 GAX20374.1 - 6.7e-11 42.5 0.1 2.4e-10 40.7 0.1 1.9 1 1 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain EamA PF00892.20 GAX20375.1 - 9.6e-26 90.6 25.1 2.7e-14 53.5 10.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF4191 PF13829.6 GAX20375.1 - 0.05 13.0 1.1 0.099 12.0 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PUNUT PF16913.5 GAX20375.1 - 0.075 12.2 4.3 0.042 13.1 1.1 2.0 3 0 0 3 3 3 0 Purine nucleobase transmembrane transport DUF4366 PF14283.6 GAX20375.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2070 PF09843.9 GAX20375.1 - 1.3 7.2 5.2 1.8 6.8 5.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1761 PF08570.10 GAX20375.1 - 7.2 6.9 14.2 0.041 14.1 1.8 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1761) Fez1 PF06818.15 GAX20377.1 - 0.024 15.1 0.5 0.035 14.6 0.5 1.2 1 0 0 1 1 1 0 Fez1 T_Ag_DNA_bind PF02217.16 GAX20377.1 - 0.16 12.6 0.3 0.4 11.3 0.3 1.7 1 1 0 1 1 1 0 Origin of replication binding protein Cpn60_TCP1 PF00118.24 GAX20379.1 - 2.9e-156 520.9 5.3 3.3e-156 520.8 5.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Adeno_E1A PF02703.14 GAX20379.1 - 0.031 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Early E1A protein SIR2 PF02146.17 GAX20380.1 - 6.2e-42 143.5 0.1 1.3e-27 96.9 0.0 2.1 2 0 0 2 2 2 2 Sir2 family zinc_ribbon_9 PF14369.6 GAX20380.1 - 0.026 14.8 0.5 3.5 8.0 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon Prok-RING_1 PF14446.6 GAX20380.1 - 0.14 12.1 4.7 0.17 11.8 0.1 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Lar_restr_allev PF14354.6 GAX20380.1 - 1.4 9.4 4.0 1.7 9.1 0.1 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar NCA2 PF08637.10 GAX20381.1 - 2.8e-19 69.4 0.2 4.3e-19 68.8 0.2 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Nop PF01798.18 GAX20381.1 - 0.23 10.9 2.5 0.36 10.3 2.5 1.2 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin CNDH2_M PF16869.5 GAX20382.1 - 0.025 15.3 3.4 0.32 11.7 0.0 2.4 2 0 0 2 2 2 0 PF16858 FH2 PF02181.23 GAX20383.1 - 5e-71 239.8 20.4 1.9e-69 234.5 20.4 2.5 1 1 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 GAX20383.1 - 5.5e-12 46.4 30.0 2.7e-09 37.6 0.1 8.2 6 3 0 6 6 6 2 Subunit CCDC53 of WASH complex DUF2730 PF10805.8 GAX20383.1 - 0.12 12.5 0.1 0.62 10.2 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) WYL_3 PF18488.1 GAX20385.1 - 0.15 12.5 0.2 0.31 11.4 0.2 1.4 1 0 0 1 1 1 0 WYL domain RNase_PH PF01138.21 GAX20386.1 - 2.9e-23 82.8 1.7 6.8e-23 81.6 0.4 2.2 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX20386.1 - 0.0011 18.9 0.2 0.002 18.1 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ACT_7 PF13840.6 GAX20387.1 - 3.3e-21 74.8 0.0 6.1e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain UreD PF01774.17 GAX20387.1 - 0.016 15.1 0.2 0.05 13.5 0.2 1.8 1 1 0 1 1 1 0 UreD urease accessory protein ACT PF01842.25 GAX20387.1 - 0.034 13.9 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 ACT domain Pim PF16765.5 GAX20391.1 - 0.093 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Pesticin immunity protein ATPgrasp_ST PF14397.6 GAX20392.1 - 6.2e-09 35.5 0.0 5.3e-08 32.4 0.0 2.2 1 1 1 2 2 2 1 Sugar-transfer associated ATP-grasp zf-NOSIP PF15906.5 GAX20394.1 - 7.4e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 GAX20394.1 - 0.0086 15.5 0.0 0.0086 15.5 0.0 2.5 2 1 1 3 3 3 1 Rtf2 RING-finger DUF5401 PF17380.2 GAX20394.1 - 0.012 13.8 3.9 0.015 13.4 3.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) GPCR_chapero_1 PF11904.8 GAX20394.1 - 0.016 14.6 0.2 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 GPCR-chaperone KOG2701 PF09762.9 GAX20394.1 - 0.3 11.3 5.2 0.53 10.5 5.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Telomere_reg-2 PF10193.9 GAX20395.1 - 3.5e-18 66.0 0.1 4.8e-17 62.4 0.0 2.6 2 0 0 2 2 2 1 Telomere length regulation protein DUF5610 PF18433.1 GAX20395.1 - 0.14 12.7 0.1 0.38 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) NPM1-C PF16276.5 GAX20396.1 - 0.11 12.5 0.2 0.56 10.2 0.1 2.0 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain UCH PF00443.29 GAX20398.1 - 7.8e-41 140.3 0.0 1.6e-40 139.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX20398.1 - 5.3e-21 75.5 0.0 8.8e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAX20399.1 - 1.1e-10 41.6 5.0 1.1e-10 41.6 5.0 2.5 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 GAX20399.1 - 9.2e-08 32.2 0.1 3.5e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 GAX20399.1 - 3.9e-07 30.3 9.5 3.9e-07 30.3 9.5 2.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX20399.1 - 3.7e-06 26.6 7.8 1.5e-05 24.6 7.8 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX20399.1 - 1.1e-05 25.2 9.9 1.1e-05 25.2 9.9 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX20399.1 - 1.4e-05 25.0 7.3 1.4e-05 25.0 7.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAX20399.1 - 4.8e-05 23.6 7.7 4.8e-05 23.6 7.7 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX20399.1 - 6.6e-05 22.7 8.3 6.6e-05 22.7 8.3 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX20399.1 - 0.0011 18.9 5.4 0.0042 17.1 4.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger AAA_23 PF13476.6 GAX20399.1 - 0.0053 17.3 2.2 0.0078 16.7 2.2 1.2 1 0 0 1 1 1 1 AAA domain APG6_N PF17675.1 GAX20399.1 - 0.018 15.5 11.5 0.035 14.6 11.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 GAX20399.1 - 0.022 14.8 7.8 0.068 13.2 7.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_3 PF13920.6 GAX20399.1 - 0.025 14.4 5.0 0.025 14.4 5.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Med9 PF07544.13 GAX20399.1 - 0.044 13.9 5.1 0.11 12.6 5.1 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PCRF PF03462.18 GAX20399.1 - 0.054 13.4 3.2 0.11 12.3 3.2 1.5 1 0 0 1 1 1 0 PCRF domain SseB_C PF14581.6 GAX20399.1 - 0.079 13.1 0.8 8.4 6.5 0.3 2.5 2 0 0 2 2 2 0 SseB protein C-terminal domain Macoilin PF09726.9 GAX20399.1 - 0.085 11.4 5.7 0.11 11.0 5.7 1.1 1 0 0 1 1 1 0 Macoilin family HAUS-augmin3 PF14932.6 GAX20399.1 - 0.12 11.9 14.5 0.18 11.4 13.8 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ZapB PF06005.12 GAX20399.1 - 0.14 12.6 18.0 0.07 13.6 10.9 2.9 1 1 1 2 2 2 0 Cell division protein ZapB DUF4164 PF13747.6 GAX20399.1 - 0.22 11.8 7.1 0.054 13.8 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FapA PF03961.13 GAX20399.1 - 0.22 10.1 2.6 0.3 9.7 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ly49 PF08391.10 GAX20399.1 - 0.22 11.9 4.9 0.6 10.5 4.9 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Seryl_tRNA_N PF02403.22 GAX20399.1 - 0.31 11.3 7.7 0.52 10.6 7.3 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 GAX20399.1 - 0.33 11.0 3.2 0.76 9.8 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 GAX20399.1 - 0.34 10.2 13.6 0.59 9.4 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 GAX20399.1 - 0.59 9.8 12.3 0.14 11.9 5.8 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 PHD PF00628.29 GAX20399.1 - 0.9 9.5 18.4 0.94 9.4 4.2 2.8 2 0 0 2 2 2 0 PHD-finger DUF2400 PF09674.10 GAX20399.1 - 1.1 9.2 4.3 1.8 8.5 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) V_ATPase_I PF01496.19 GAX20399.1 - 2 6.2 6.5 2.6 5.8 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 GAX20399.1 - 3 8.5 10.6 2.2 8.9 6.3 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Cep57_MT_bd PF06657.13 GAX20399.1 - 3.6 8.1 12.6 1.4 9.4 4.5 2.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PHF5 PF03660.14 GAX20399.1 - 3.7 7.8 10.2 1.6 9.0 6.9 2.0 1 1 1 2 2 2 0 PHF5-like protein zf-ANAPC11 PF12861.7 GAX20399.1 - 6.5 6.9 14.5 0.086 12.9 5.3 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exonuc_VII_L PF02601.15 GAX20399.1 - 7.2 6.1 12.6 13 5.2 12.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2205 PF10224.9 GAX20399.1 - 9.6 6.3 10.4 3.1 7.9 5.7 2.4 1 1 1 2 2 2 0 Short coiled-coil protein PX PF00787.24 GAX20400.1 - 0.11 12.4 2.5 0.15 12.1 0.3 2.1 2 0 0 2 2 2 0 PX domain LIM_bind PF01803.16 GAX20400.1 - 1 8.8 5.7 5.2 6.5 3.3 2.2 2 0 0 2 2 2 0 LIM-domain binding protein Mito_carr PF00153.27 GAX20401.1 - 2.3e-21 75.5 0.2 2.2e-09 37.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-binding PF00249.31 GAX20402.1 - 3.6e-53 177.5 16.4 6.4e-19 67.9 0.9 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX20402.1 - 1.7e-39 133.8 7.0 2.6e-15 56.4 1.0 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 GAX20402.1 - 3.4e-10 40.0 0.0 0.021 14.9 0.0 3.3 2 1 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 GAX20402.1 - 0.00034 20.4 0.4 0.19 11.7 0.0 2.6 3 0 0 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 GAX20402.1 - 0.0092 16.1 11.2 0.41 10.8 0.5 3.2 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 GAX20402.1 - 0.39 10.9 1.0 6.3 7.1 0.1 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 RVT_2 PF07727.14 GAX20404.1 - 7.7e-18 65.0 0.0 2.8e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX20404.1 - 0.0028 17.7 2.2 0.0061 16.6 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF1654 PF07867.11 GAX20404.1 - 0.17 11.6 0.1 0.64 9.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) zf-CCHC_2 PF13696.6 GAX20404.1 - 0.34 10.8 1.2 1.2 9.1 1.2 1.9 1 0 0 1 1 1 0 Zinc knuckle Pro_isomerase PF00160.21 GAX20406.1 - 5.3e-07 30.0 0.0 9.1e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DNA_pol_A_exo1 PF01612.20 GAX20409.1 - 1.6e-15 57.3 0.1 2.6e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease tRNA_edit PF04073.15 GAX20409.1 - 1.9e-12 47.3 0.0 3.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HBM PF16591.5 GAX20409.1 - 0.072 12.5 0.3 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain Form_Nir_trans PF01226.17 GAX20410.1 - 4.3e-70 235.7 17.4 4.9e-70 235.5 17.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2583 PF10762.9 GAX20410.1 - 0.017 15.6 6.4 0.019 15.3 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2583) RhodobacterPufX PF11511.8 GAX20410.1 - 4.1 7.1 6.4 0.34 10.6 0.6 2.2 2 1 0 2 2 2 0 Intrinsic membrane protein PufX Na_H_Exchanger PF00999.21 GAX20414.1 - 1.3e-43 149.3 34.7 1.5e-43 149.0 34.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PCRF PF03462.18 GAX20416.1 - 8.8e-69 231.3 0.4 2.8e-68 229.6 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAX20416.1 - 5e-38 129.6 1.1 5e-38 129.6 1.1 1.9 2 0 0 2 2 2 1 RF-1 domain Glyco_hydro_30 PF02055.16 GAX20420.1 - 2.9e-57 194.2 0.1 6e-57 193.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 GAX20420.1 - 1.1e-07 32.0 0.0 6.4e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 GAX20420.1 - 0.004 16.4 2.5 0.019 14.2 2.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Ricin_B_lectin PF00652.22 GAX20420.1 - 0.019 15.2 0.1 7.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 GAX20421.1 - 2.6e-10 40.4 0.0 7.4e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX20421.1 - 0.0003 20.8 0.0 0.0019 18.1 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Sulfotransfer_3 PF13469.6 GAX20421.1 - 0.024 15.0 0.8 0.049 14.0 0.8 1.5 1 0 0 1 1 1 0 Sulfotransferase family Cupin_8 PF13621.6 GAX20422.1 - 8.9e-20 71.5 3.9 5.8e-19 68.8 1.2 2.8 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 GAX20422.1 - 4.9e-10 39.8 0.5 5e-09 36.6 0.2 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase F-box-like PF12937.7 GAX20422.1 - 2.8e-05 23.9 1.4 0.00011 22.1 0.2 2.3 2 0 0 2 2 2 1 F-box-like Cupin_4 PF08007.12 GAX20422.1 - 4.7e-05 23.0 0.0 8.8e-05 22.1 0.0 1.4 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_1 PF00190.22 GAX20422.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Cupin Elongin_A PF06881.11 GAX20422.1 - 0.16 12.5 0.1 0.59 10.7 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Cupin_2 PF07883.11 GAX20422.1 - 0.19 11.5 0.3 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Methyltrans_SAM PF10672.9 GAX20423.1 - 2.5e-20 72.8 0.0 4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 GAX20423.1 - 2.5e-07 30.5 0.0 5.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 GAX20423.1 - 0.0016 18.1 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RPAP1_N PF08621.10 GAX20423.1 - 0.091 12.5 1.2 7.5 6.4 0.1 2.9 3 0 0 3 3 3 0 RPAP1-like, N-terminal AAA_25 PF13481.6 GAX20423.1 - 0.097 12.2 0.0 0.37 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain MBOAT PF03062.19 GAX20424.1 - 1.1e-29 103.9 7.5 1.1e-29 103.9 7.5 2.3 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PsbX PF06596.11 GAX20424.1 - 0.76 9.8 5.8 0.37 10.8 0.2 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) PT PF04886.12 GAX20425.1 - 0.00057 19.4 11.8 0.00057 19.4 11.8 33.9 20 9 8 28 28 28 11 PT repeat Yae1_N PF09811.9 GAX20427.1 - 9.5e-10 38.0 131.8 0.085 12.6 0.4 26.4 12 7 13 26 26 26 20 Essential protein Yae1, N terminal PT PF04886.12 GAX20428.1 - 7.1e-07 28.7 79.2 0.00014 21.3 14.7 26.1 18 6 8 26 26 26 13 PT repeat Cyclin_N PF00134.23 GAX20429.1 - 2e-49 166.5 2.4 9.8e-46 154.6 1.4 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX20429.1 - 2.3e-25 89.0 0.0 5.1e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Sugar_tr PF00083.24 GAX20430.1 - 1.2e-37 129.9 10.9 1.6e-37 129.5 10.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX20430.1 - 8.5e-33 113.7 47.7 1.5e-22 80.0 31.7 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily His_Phos_1 PF00300.22 GAX20431.1 - 2.1e-34 118.9 0.0 2.5e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HA PF03457.14 GAX20432.1 - 3.5e-09 36.9 0.1 7e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain Ham1p_like PF01725.16 GAX20433.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Ham1 family EamA PF00892.20 GAX20434.1 - 1.1e-20 74.2 29.8 1.2e-12 48.2 6.8 3.6 4 0 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.15 GAX20434.1 - 0.0051 16.0 0.2 0.47 9.6 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter MerC PF03203.14 GAX20434.1 - 0.11 13.0 4.6 0.53 10.8 0.9 2.9 2 0 0 2 2 2 0 MerC mercury resistance protein HSF_DNA-bind PF00447.17 GAX20436.1 - 1.2e-21 77.1 0.1 3.2e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Mpv17_PMP22 PF04117.12 GAX20437.1 - 9.7e-15 54.6 0.3 1.8e-14 53.7 0.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Trp_oprn_chp PF09534.10 GAX20440.1 - 5.1 6.9 10.4 1.4e+02 2.2 10.5 2.7 3 1 1 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Peptidase_U4 PF03419.13 GAX20440.1 - 9.4 5.4 12.5 1.3 8.3 1.7 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF2518 PF10726.9 GAX20441.1 - 0.017 14.8 7.5 0.27 10.9 0.5 2.4 2 0 0 2 2 2 0 Protein of function (DUF2518) MnhB PF04039.13 GAX20441.1 - 0.017 15.4 1.4 0.017 15.4 1.4 3.0 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter Peptidase_U4 PF03419.13 GAX20441.1 - 1.8 7.8 10.4 0.46 9.7 1.4 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Snf7 PF03357.21 GAX20443.1 - 1.3e-29 103.0 13.5 1.5e-29 102.8 13.5 1.1 1 0 0 1 1 1 1 Snf7 EPOP PF15223.6 GAX20443.1 - 0.076 12.4 1.0 0.11 11.8 0.7 1.5 1 1 1 2 2 2 0 Elongin BC and Polycomb repressive complex 2-associated protein DivIC PF04977.15 GAX20443.1 - 3.6 7.4 7.5 0.58 10.0 2.4 2.2 2 0 0 2 2 2 0 Septum formation initiator DNA_pol_B_palm PF14792.6 GAX20444.1 - 0.017 15.3 0.1 0.022 15.0 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase beta palm TPR_2 PF07719.17 GAX20445.1 - 0.043 13.9 0.3 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 GAX20446.1 - 3.3e-06 26.8 0.0 6.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nic96 PF04097.14 GAX20446.1 - 0.035 12.6 0.1 0.048 12.1 0.1 1.1 1 0 0 1 1 1 0 Nup93/Nic96 Ctr PF04145.15 GAX20447.1 - 6.7e-15 56.0 12.0 1.9e-12 48.0 12.0 2.2 1 1 0 1 1 1 1 Ctr copper transporter family RNA_pol_Rpc4 PF05132.14 GAX20448.1 - 0.017 15.6 2.1 0.025 15.0 2.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 GAX20448.1 - 0.063 12.1 1.8 0.069 11.9 1.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 GAX20448.1 - 0.13 12.1 11.8 0.16 11.7 11.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GAX20448.1 - 0.36 9.6 8.4 0.47 9.2 8.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1840 PF08895.11 GAX20448.1 - 1.1 9.6 7.0 2.4 8.5 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Spore_coat_CotO PF14153.6 GAX20448.1 - 1.2 9.1 13.3 1.5 8.7 13.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CPSF100_C PF13299.6 GAX20448.1 - 1.2 9.3 7.2 1.9 8.6 7.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 GAX20448.1 - 2.5 7.0 5.1 2.8 6.8 5.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 GAX20448.1 - 3.4 7.4 13.3 4.5 7.0 13.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Paf1 PF03985.13 GAX20448.1 - 4.4 6.2 28.3 6.2 5.7 28.3 1.1 1 0 0 1 1 1 0 Paf1 NPR3 PF03666.13 GAX20448.1 - 4.7 5.9 9.9 5.6 5.6 9.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 GAX20448.1 - 4.8 5.2 37.4 5.7 4.9 37.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 GAX20448.1 - 6.5 6.0 30.0 7.9 5.7 30.0 1.1 1 0 0 1 1 1 0 BUD22 Connexin PF00029.19 GAX20448.1 - 6.9 6.4 4.6 9.7 5.9 4.6 1.3 1 0 0 1 1 1 0 Connexin PPL5 PF18168.1 GAX20448.1 - 9.1 5.5 6.3 12 5.1 6.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Thioredoxin_16 PF18569.1 GAX20451.1 - 0.024 14.8 0.8 0.088 12.9 0.8 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain EBP PF05241.12 GAX20452.1 - 5.9e-29 100.8 7.7 1.2e-28 99.7 7.7 1.5 1 0 0 1 1 1 1 Emopamil binding protein Aminotran_5 PF00266.19 GAX20452.1 - 3.3e-21 75.7 0.0 9.5e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 GAX20452.1 - 1.9e-20 72.9 0.0 4.1e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 GAX20452.1 - 1.5e-15 57.4 0.1 3e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 MOSC domain CBM_14 PF01607.24 GAX20453.1 - 2.4e-06 27.6 5.6 2.4e-06 27.6 5.6 2.9 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Solute_trans_a PF03619.16 GAX20454.1 - 9e-71 238.5 12.8 9e-71 238.5 12.8 1.4 2 0 0 2 2 2 1 Organic solute transporter Ostalpha DUF4381 PF14316.6 GAX20454.1 - 0.046 13.9 3.1 0.35 11.1 1.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF2500 PF10694.9 GAX20454.1 - 0.15 12.5 1.7 0.21 12.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Glyco_trans_1_4 PF13692.6 GAX20455.1 - 6e-08 33.2 0.0 1.3e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX20455.1 - 4.4e-07 29.6 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Guanylate_kin PF00625.21 GAX20456.1 - 7.3e-58 195.2 0.0 8.3e-58 195.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 GAX20456.1 - 0.00026 20.9 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 GAX20456.1 - 0.00028 21.1 0.1 0.0026 17.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX20456.1 - 0.00066 20.2 0.0 0.0015 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain Methyltransf_25 PF13649.6 GAX20456.1 - 0.0012 19.5 0.1 0.075 13.7 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX20456.1 - 0.0015 19.1 0.0 0.064 13.9 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain AAA_7 PF12775.7 GAX20456.1 - 0.0044 16.5 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 GAX20456.1 - 0.0058 16.7 0.0 0.0092 16.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX20456.1 - 0.0065 16.9 0.0 0.01 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 GAX20456.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 GAX20456.1 - 0.011 16.0 0.0 0.026 14.9 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_5 PF07728.14 GAX20456.1 - 0.021 14.9 0.1 0.33 10.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_12 PF08242.12 GAX20456.1 - 0.026 15.3 0.0 0.13 13.0 0.0 2.1 1 1 0 2 2 2 0 Methyltransferase domain NTPase_1 PF03266.15 GAX20456.1 - 0.059 13.3 0.1 0.093 12.6 0.1 1.5 1 1 0 1 1 1 0 NTPase AAA_17 PF13207.6 GAX20456.1 - 0.059 13.8 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX20456.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 GAX20456.1 - 0.073 13.3 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 GAX20456.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PTS_IIB PF02302.17 GAX20456.1 - 0.11 13.2 0.2 9.7 7.0 0.0 2.9 1 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit ABC_tran PF00005.27 GAX20456.1 - 0.13 12.7 0.1 0.2 12.2 0.1 1.7 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 GAX20456.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 GAX20456.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 GAX20456.1 - 0.17 11.6 0.2 0.59 9.8 0.2 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein Acetyltransf_3 PF13302.7 GAX20457.1 - 1.4e-19 71.2 0.0 1.7e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX20457.1 - 0.0041 17.3 0.0 0.007 16.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Fringe PF02434.16 GAX20457.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Fringe-like TRAM_LAG1_CLN8 PF03798.16 GAX20458.1 - 8.7e-12 45.2 19.5 1.5e-11 44.5 19.5 1.5 1 1 0 1 1 1 1 TLC domain Methyltransf_25 PF13649.6 GAX20459.1 - 8.3e-16 58.5 0.1 2.1e-15 57.2 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX20459.1 - 2.3e-15 56.8 0.0 2.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX20459.1 - 5.2e-14 52.3 0.0 6.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX20459.1 - 1e-13 51.9 0.0 1.7e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX20459.1 - 7.8e-13 48.9 0.1 2.9e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX20459.1 - 1.6e-06 27.8 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.16 GAX20459.1 - 5.8e-06 25.6 0.0 6.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme FtsJ PF01728.19 GAX20459.1 - 6.6e-06 26.4 0.1 3.8e-05 23.9 0.1 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAX20459.1 - 7.1e-06 25.5 0.1 1.4e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 GAX20459.1 - 1.4e-05 24.9 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 GAX20459.1 - 2e-05 24.1 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 GAX20459.1 - 5e-05 22.5 0.1 6.8e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 GAX20459.1 - 0.00026 20.4 0.2 0.00037 19.9 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 GAX20459.1 - 0.00056 19.6 0.1 0.00078 19.2 0.1 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 GAX20459.1 - 0.00071 19.0 0.0 0.0016 17.9 0.0 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 GAX20459.1 - 0.0011 18.9 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 GAX20459.1 - 0.0016 17.6 0.0 0.0031 16.6 0.0 1.4 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_PK PF05891.12 GAX20459.1 - 0.0016 18.0 0.1 0.002 17.7 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 GAX20459.1 - 0.004 16.9 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DUF3419 PF11899.8 GAX20459.1 - 0.0046 16.2 0.0 0.0087 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) DUF1188 PF06690.11 GAX20459.1 - 0.053 13.1 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) AdoMet_MTase PF07757.13 GAX20459.1 - 0.076 13.4 0.1 0.13 12.6 0.1 1.5 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_9 PF08003.11 GAX20459.1 - 0.092 11.6 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CheR PF01739.18 GAX20459.1 - 0.093 12.2 0.0 0.87 9.0 0.0 2.2 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain MethyltransfD12 PF02086.15 GAX20459.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_18 PF12847.7 GAX20459.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_22 PF03901.17 GAX20461.1 - 2.2e-54 185.3 29.3 1.2e-53 182.8 29.3 2.1 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family TetR PF13972.6 GAX20461.1 - 0.064 13.0 0.6 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF4337 PF14235.6 GAX20461.1 - 0.19 11.9 0.0 0.83 9.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Ribosomal_S17e PF00833.18 GAX20462.1 - 6.2e-59 197.3 0.1 6.9e-59 197.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 bVLRF1 PF18826.1 GAX20463.1 - 4.8e-40 136.9 0.1 4.8e-40 136.9 0.1 2.3 2 0 0 2 2 1 1 bacteroidetes VLRF1 release factor Ank_4 PF13637.6 GAX20463.1 - 3.5e-08 33.8 0.0 2.9e-07 30.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX20463.1 - 8e-08 32.8 0.0 1.9e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) VATC PF18716.1 GAX20463.1 - 2.2e-07 30.6 4.0 5e-07 29.5 4.0 1.6 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_3 PF13606.6 GAX20463.1 - 7.4e-07 29.0 0.1 0.0038 17.6 0.0 2.9 3 0 0 3 3 2 2 Ankyrin repeat Ank PF00023.30 GAX20463.1 - 3.9e-06 27.1 0.1 0.0065 16.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAX20463.1 - 0.0014 18.9 0.2 0.21 12.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Presenilin PF01080.17 GAX20463.1 - 0.18 10.6 18.6 0.61 8.8 3.8 2.2 2 0 0 2 2 2 0 Presenilin Vfa1 PF08432.10 GAX20463.1 - 0.28 11.5 24.8 0.25 11.7 5.7 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SR-25 PF10500.9 GAX20463.1 - 0.35 10.4 30.0 0.23 11.1 9.2 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nop53 PF07767.11 GAX20463.1 - 0.55 9.6 39.9 0.46 9.8 16.6 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) MAP7 PF05672.11 GAX20463.1 - 0.55 9.9 43.1 0.15 11.7 19.0 2.5 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family PRP1_N PF06424.12 GAX20463.1 - 1.2 9.5 25.2 0.24 11.8 9.7 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Borrelia_P83 PF05262.11 GAX20463.1 - 2.6 6.4 28.3 0.16 10.4 7.8 2.3 2 0 0 2 2 2 0 Borrelia P83/100 protein Mpp10 PF04006.12 GAX20463.1 - 2.8 6.3 33.3 0.74 8.2 12.4 2.1 2 0 0 2 2 2 0 Mpp10 protein DUF2052 PF09747.9 GAX20463.1 - 3 7.9 26.5 1.4 9.1 6.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CCDC53 PF10152.9 GAX20463.1 - 3.8 7.9 18.8 0.095 13.1 0.5 2.8 3 0 0 3 3 2 0 Subunit CCDC53 of WASH complex CDC45 PF02724.14 GAX20463.1 - 3.9 5.7 29.4 3.4 5.8 14.5 2.1 2 0 0 2 2 2 0 CDC45-like protein SAPS PF04499.15 GAX20463.1 - 5.6 5.6 15.5 1.9 7.2 1.3 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 GAX20463.1 - 7.2 6.4 23.2 0.79 9.5 0.8 2.9 3 0 0 3 3 3 0 SpoIIIAH-like protein Hid1 PF12722.7 GAX20463.1 - 9 4.3 19.0 3.5 5.6 8.4 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 GAX20463.1 - 9.7 5.9 30.9 7.4 6.3 10.5 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 adh_short PF00106.25 GAX20464.1 - 7.2e-14 51.7 0.0 2.1e-11 43.6 0.0 2.7 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX20464.1 - 6.7e-07 29.1 0.0 2.9e-05 23.7 0.0 2.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX20464.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 GAX20464.1 - 0.068 12.6 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_16 PF10294.9 GAX20465.1 - 7.8e-21 74.6 0.1 1.7e-20 73.5 0.1 1.6 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAX20465.1 - 1.8e-05 24.3 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX20465.1 - 5.1e-05 22.9 0.0 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX20465.1 - 0.0002 22.0 0.0 0.00053 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX20465.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein NNMT_PNMT_TEMT PF01234.17 GAX20465.1 - 0.0044 16.2 0.0 0.0064 15.7 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 GAX20465.1 - 0.024 14.4 0.3 0.043 13.6 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase domain FMN_red PF03358.15 GAX20465.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DEDD_Tnp_IS110 PF01548.17 GAX20465.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Transposase HGTP_anticodon PF03129.20 GAX20466.1 - 9.1e-22 77.0 0.5 2.2e-21 75.8 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAX20466.1 - 1.4e-10 41.4 0.0 1.1e-09 38.6 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Auto_anti-p27 PF06677.12 GAX20467.1 - 1.9e-23 82.3 29.0 7.8e-13 48.4 4.5 4.4 4 0 0 4 4 4 3 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.14 GAX20467.1 - 0.007 16.7 7.1 1.2 9.5 0.0 4.3 3 1 1 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Phlebovirus_NSM PF07246.11 GAX20467.1 - 0.28 10.5 5.3 0.55 9.6 5.3 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DZR PF12773.7 GAX20467.1 - 9.3 6.4 15.6 8.5 6.5 0.5 4.1 4 0 0 4 4 4 0 Double zinc ribbon Ribosomal_S11 PF00411.19 GAX20468.1 - 9.4e-47 158.0 0.3 1.2e-46 157.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 GAX20468.1 - 0.13 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme ACT_6 PF13740.6 GAX20469.1 - 7.1e-19 67.6 0.3 2e-14 53.3 0.1 2.3 2 1 0 2 2 2 2 ACT domain ACT PF01842.25 GAX20469.1 - 9.7e-09 34.9 0.0 2.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 GAX20469.1 - 1.4e-08 35.1 0.0 0.0067 17.0 0.0 2.2 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 GAX20469.1 - 0.0077 16.0 1.7 0.012 15.4 0.0 2.1 3 0 0 3 3 3 1 ACT domain Hist_deacetyl PF00850.19 GAX20470.1 - 8.3e-44 150.3 0.0 1.9e-43 149.1 0.0 1.6 1 1 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 GAX20470.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 NIL domain Lipase_3 PF01764.25 GAX20471.1 - 1.8e-15 57.1 0.0 8.6e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAX20471.1 - 0.0038 16.5 0.0 0.01 15.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 GAX20471.1 - 0.0095 15.5 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 GAX20471.1 - 0.1 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX20471.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DDDD PF10161.9 GAX20471.1 - 0.18 11.6 0.1 0.49 10.2 0.1 1.7 2 0 0 2 2 2 0 Putative mitochondrial precursor protein RXT2_N PF08595.11 GAX20471.1 - 0.23 11.5 7.3 0.13 12.3 2.9 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Phage_Gp23 PF10669.9 GAX20471.1 - 0.54 10.6 8.2 1.7 9.0 8.2 1.8 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) U79_P34 PF03064.16 GAX20471.1 - 8.1 5.7 9.0 16 4.8 9.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Lipase_3 PF01764.25 GAX20472.1 - 3.5e-16 59.4 0.0 7.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAX20472.1 - 0.007 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX20472.1 - 0.085 13.4 0.0 0.24 12.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Nuc_deoxyri_tr2 PF15891.5 GAX20472.1 - 0.11 12.8 0.3 1.8 8.9 0.1 2.8 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase like PGAP1 PF07819.13 GAX20472.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein MEDS PF14417.6 GAX20472.1 - 0.18 11.6 0.7 2.1 8.2 0.2 2.7 3 0 0 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Sec7 PF01369.20 GAX20473.1 - 3.2e-59 199.7 0.3 5.5e-59 198.9 0.3 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAX20473.1 - 1.5e-24 86.7 0.6 5.2e-24 84.9 0.6 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Caerin_1 PF07440.12 GAX20473.1 - 0.25 11.4 7.5 0.8 9.9 0.7 2.8 3 0 0 3 3 3 0 Caerin 1 protein PseudoU_synth_1 PF01416.20 GAX20474.1 - 1.1e-33 115.9 0.0 2.5e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase CTP_transf_like PF01467.26 GAX20475.1 - 5.3e-06 26.7 0.0 1.3e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 GAX20475.1 - 0.17 11.4 0.0 0.35 10.3 0.0 1.5 2 0 0 2 2 2 0 ATP-sulfurylase DUF389 PF04087.14 GAX20476.1 - 2.1e-40 138.0 2.2 2.1e-40 138.0 2.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF389) PHO4 PF01384.20 GAX20476.1 - 0.0031 16.6 2.0 0.051 12.6 1.6 2.1 1 1 1 2 2 2 2 Phosphate transporter family PIG-F PF06699.11 GAX20476.1 - 0.0044 17.2 0.3 0.0075 16.4 0.3 1.4 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2157 PF09925.9 GAX20476.1 - 0.053 13.3 1.4 0.15 11.8 1.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF389 PF04087.14 GAX20477.1 - 3.5e-39 134.1 2.5 3.5e-39 134.1 2.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF389) DUF2157 PF09925.9 GAX20477.1 - 0.00096 19.0 1.9 0.0029 17.4 1.9 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) PHO4 PF01384.20 GAX20477.1 - 0.0066 15.5 0.9 0.058 12.4 0.8 1.9 1 1 1 2 2 2 1 Phosphate transporter family PIG-F PF06699.11 GAX20477.1 - 0.026 14.7 0.3 0.044 14.0 0.3 1.4 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F DUF2256 PF10013.9 GAX20478.1 - 3.2e-18 65.5 13.6 3.2e-18 65.5 13.6 2.8 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2256) Med2 PF11214.8 GAX20478.1 - 0.013 15.6 0.9 0.019 15.1 0.2 1.6 1 1 0 1 1 1 0 Mediator complex subunit 2 zf-NADH-PPase PF09297.11 GAX20478.1 - 0.065 12.9 0.2 0.065 12.9 0.2 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Cupin_4 PF08007.12 GAX20479.1 - 5.6e-53 180.5 0.6 1.1e-52 179.6 0.6 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 GAX20479.1 - 4.2e-08 33.2 7.7 2.9e-07 30.5 4.4 3.3 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.22 GAX20479.1 - 0.13 12.7 0.0 0.97 9.9 0.0 2.5 1 1 0 1 1 1 0 JmjC domain, hydroxylase HSF_DNA-bind PF00447.17 GAX20480.1 - 6e-19 68.5 2.1 1.6e-18 67.1 0.0 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding Mannitol_dh_C PF08125.13 GAX20481.1 - 5.7e-70 235.6 0.0 8e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 GAX20481.1 - 3e-36 124.9 0.0 5.2e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Ank_2 PF12796.7 GAX20482.1 - 9e-31 106.3 5.4 3.4e-16 59.6 0.4 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Methyltransf_16 PF10294.9 GAX20482.1 - 8e-29 100.6 0.0 1.3e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ank_4 PF13637.6 GAX20482.1 - 9.7e-17 61.1 0.3 1.7e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX20482.1 - 1e-15 56.2 0.2 7e-06 26.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX20482.1 - 1.8e-15 56.6 0.9 8.5e-07 29.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX20482.1 - 2e-14 53.4 3.3 2.9e-07 30.6 0.0 4.0 2 1 2 4 4 3 2 Ankyrin repeats (many copies) PrmA PF06325.13 GAX20482.1 - 2.6e-07 30.4 0.0 5.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX20482.1 - 2.9e-07 30.2 0.0 5.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX20482.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20482.1 - 9.1e-06 26.3 0.0 3.1e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX20482.1 - 4.9e-05 23.2 0.0 7.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein GidB PF02527.15 GAX20482.1 - 5.1e-05 22.7 0.0 0.00024 20.5 0.0 1.9 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 GAX20482.1 - 0.016 15.9 0.0 0.037 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAX20482.1 - 0.017 15.8 0.0 0.058 14.0 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX20482.1 - 0.024 14.3 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TRM PF02005.16 GAX20482.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 GAX20482.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Fasciclin PF02469.22 GAX20483.1 - 3.3e-47 159.9 0.0 2.6e-22 79.4 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain AP_endonuc_2 PF01261.24 GAX20485.1 - 0.00036 20.0 0.2 0.0033 16.9 0.0 2.3 2 1 1 3 3 3 1 Xylose isomerase-like TIM barrel CDC37_N PF03234.14 GAX20486.1 - 6.6 7.7 13.5 1.1 10.1 8.8 2.2 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding RCC1 PF00415.18 GAX20487.1 - 6.9e-39 132.2 11.6 3.6e-06 27.5 0.0 8.0 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX20487.1 - 4.3e-28 96.5 19.4 7.2e-07 28.9 0.4 7.7 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Cofac_haem_bdg PF04187.13 GAX20488.1 - 8.2e-43 146.9 0.1 1.8e-42 145.7 0.1 1.6 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN Methyltransf_31 PF13847.6 GAX20488.1 - 3.4e-25 88.6 0.0 7.7e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX20488.1 - 1.9e-21 76.5 0.0 3.9e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20488.1 - 3.5e-21 75.7 0.0 8.2e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX20488.1 - 3.5e-13 49.7 0.0 7.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX20488.1 - 6.9e-13 48.5 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX20488.1 - 1.3e-10 41.9 0.0 3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX20488.1 - 3.7e-09 36.6 0.0 6.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAX20488.1 - 8.7e-09 35.1 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAX20488.1 - 2.4e-06 27.2 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX20488.1 - 2.8e-06 26.9 0.0 6.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 GAX20488.1 - 8.6e-05 22.6 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAX20488.1 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 GAX20488.1 - 0.0038 17.3 0.0 0.0074 16.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 GAX20488.1 - 0.0039 16.5 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 GAX20488.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.12 GAX20488.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Erythro_esteras PF05139.14 GAX20488.1 - 0.014 15.2 2.5 0.073 12.9 0.0 2.5 2 1 0 2 2 2 0 Erythromycin esterase DUF366 PF04017.12 GAX20488.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF366) DOT1 PF08123.13 GAX20488.1 - 0.15 11.6 0.0 0.6 9.6 0.0 1.9 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 GAX20488.1 - 0.16 11.4 0.0 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Trypsin PF00089.26 GAX20489.1 - 1.1e-09 38.4 0.1 2.7e-09 37.2 0.1 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX20489.1 - 1.2e-08 35.9 0.0 2.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 GAX20489.1 - 0.11 11.1 0.1 5.8 5.4 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 DAO PF01266.24 GAX20490.1 - 3.6e-32 112.3 0.2 4.2e-32 112.1 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX20490.1 - 1.3e-05 25.2 1.1 3.5e-05 23.8 0.3 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAX20490.1 - 0.00023 21.4 0.2 0.00049 20.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX20490.1 - 0.014 14.5 0.4 0.022 13.8 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 GAX20490.1 - 0.014 14.2 0.6 0.31 9.8 0.2 2.5 3 0 0 3 3 3 0 MCRA family Cellulase PF00150.18 GAX20493.1 - 8.7e-37 127.1 7.4 1.5e-36 126.3 7.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_6 PF03422.15 GAX20493.1 - 1.1e-22 80.7 2.5 1.7e-22 80.0 2.5 1.3 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX20493.1 - 1.6e-10 41.1 1.5 2.9e-10 40.3 1.5 1.4 1 0 0 1 1 1 1 DUF5010 C-terminal domain tRNA-synt_2b PF00587.25 GAX20495.1 - 5e-30 104.8 0.0 3.9e-29 101.9 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAX20495.1 - 1.6e-12 47.6 6.8 3.1e-12 46.7 6.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 GAX20495.1 - 0.096 12.8 8.9 0.33 11.1 8.7 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Laminin_G_3 PF13385.6 GAX20496.1 - 5.2e-06 26.7 0.1 1e-05 25.7 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Prp18 PF02840.15 GAX20497.1 - 1.6e-59 200.0 0.2 1.6e-59 200.0 0.2 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 GAX20497.1 - 2e-09 36.8 0.7 4.4e-09 35.7 0.7 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like GEMIN8 PF15348.6 GAX20497.1 - 0.024 15.0 4.4 0.038 14.3 4.4 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DnaJ PF00226.31 GAX20498.1 - 3.8e-15 55.8 0.0 5.4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 GAX20498.1 - 2.5e-05 23.9 1.5 9.5e-05 22.1 1.5 1.9 1 1 0 1 1 1 1 CSL zinc finger Band_7 PF01145.25 GAX20499.1 - 1.2e-22 80.7 0.3 1.9e-22 80.1 0.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family TPR_2 PF07719.17 GAX20500.1 - 0.0035 17.3 0.9 0.028 14.5 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX20500.1 - 0.0037 17.7 0.1 0.0085 16.6 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX20500.1 - 0.0044 17.7 0.1 0.076 13.9 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX20500.1 - 0.0051 16.6 0.4 2.8 7.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX20500.1 - 0.0053 17.1 0.0 0.034 14.5 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX20500.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 GAX20500.1 - 0.12 12.7 0.5 1.2 9.5 0.4 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2530 PF10745.9 GAX20501.1 - 0.085 13.1 0.0 0.094 13.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) Laminin_G_3 PF13385.6 GAX20502.1 - 0.0015 18.7 0.0 0.0026 17.9 0.0 1.4 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily MOSC PF03473.17 GAX20502.1 - 0.11 12.5 0.0 0.71 9.9 0.0 2.0 1 1 0 1 1 1 0 MOSC domain DGF-1_C PF11040.8 GAX20504.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.4 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Cwf_Cwc_15 PF04889.12 GAX20504.1 - 8.8 6.0 8.4 19 4.9 8.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 GAX20505.1 - 0.0043 14.9 0.3 0.0055 14.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Tis11B_N PF04553.12 GAX20505.1 - 0.5 10.9 2.5 0.53 10.9 0.0 2.2 3 0 0 3 3 3 0 Tis11B like protein, N terminus HEAT PF02985.22 GAX20506.1 - 0.43 11.0 2.8 6.9 7.2 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat SpoVG PF04026.12 GAX20507.1 - 0.11 12.6 0.0 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 SpoVG zf-C2H2_jaz PF12171.8 GAX20507.1 - 0.12 12.7 0.9 0.4 11.0 0.9 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Leu_zip PF15294.6 GAX20507.1 - 0.17 11.4 2.2 11 5.5 0.1 2.2 2 0 0 2 2 2 0 Leucine zipper PsbP PF01789.16 GAX20508.1 - 9.5e-15 55.1 0.0 1.2e-13 51.5 0.0 2.3 1 1 0 1 1 1 1 PsbP Rib_recp_KP_reg PF05104.12 GAX20510.1 - 3.4 8.7 8.8 5 8.2 8.8 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region LPMO_10 PF03067.15 GAX20511.1 - 1.9e-22 80.9 0.5 2.5e-22 80.5 0.5 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Patatin PF01734.22 GAX20512.1 - 4.2e-12 46.7 1.0 1.8e-10 41.4 1.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase CBFB_NFYA PF02045.15 GAX20514.1 - 4.5e-23 81.6 9.4 7.8e-23 80.9 9.4 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MutL PF13941.6 GAX20514.1 - 0.087 11.4 0.1 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 MutL protein GET2 PF08690.10 GAX20514.1 - 5.5 6.6 8.5 1.3 8.6 5.6 1.5 1 1 1 2 2 2 0 GET complex subunit GET2 ABC1 PF03109.16 GAX20515.1 - 2.5e-31 108.3 0.0 4.2e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Latarcin PF10279.9 GAX20516.1 - 0.0061 16.9 0.9 0.017 15.5 0.3 2.2 2 1 0 2 2 2 1 Latarcin precursor ISG65-75 PF11727.8 GAX20516.1 - 0.29 10.3 9.4 0.15 11.2 7.1 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein PAP2 PF01569.21 GAX20517.1 - 0.012 15.4 0.4 0.12 12.1 0.1 2.3 1 1 1 2 2 2 0 PAP2 superfamily Scs3p PF10261.9 GAX20517.1 - 0.026 14.1 0.3 0.061 12.8 0.1 1.6 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM SIP1 PF04938.12 GAX20518.1 - 2.5e-29 102.6 0.1 3.2e-29 102.2 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) OsmC PF02566.19 GAX20519.1 - 8.8e-09 35.8 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein DUF1897 PF09005.10 GAX20519.1 - 0.05 13.1 0.3 0.1 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) ERO1 PF04137.15 GAX20520.1 - 2.4e-88 296.7 0.8 3.2e-88 296.3 0.8 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) FAD_binding_2 PF00890.24 GAX20520.1 - 1.3e-84 284.7 0.9 1.8e-84 284.3 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 GAX20520.1 - 1.7e-18 66.5 0.0 4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 GAX20520.1 - 5e-10 39.5 3.3 2.9e-08 33.7 3.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX20520.1 - 1.1e-06 28.1 0.3 4.9e-06 26.0 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX20520.1 - 3.2e-06 26.8 1.5 7.1e-06 25.6 1.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX20520.1 - 6.9e-06 26.2 0.4 3.4e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAX20520.1 - 0.00041 19.2 0.6 0.015 14.1 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 GAX20520.1 - 0.00058 19.3 2.4 0.042 13.1 0.2 2.6 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAX20520.1 - 0.0012 18.2 1.3 0.33 10.2 0.8 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX20520.1 - 0.003 16.7 0.7 0.062 12.4 0.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAX20520.1 - 0.0045 16.3 1.5 0.0099 15.2 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAX20520.1 - 0.0056 16.0 2.0 0.0094 15.2 0.1 2.3 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 GAX20520.1 - 0.011 16.2 0.9 1.2 9.8 0.2 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAX20520.1 - 0.024 13.5 0.1 0.097 11.4 0.1 1.8 2 0 0 2 2 2 0 MCRA family NAD_binding_9 PF13454.6 GAX20520.1 - 0.07 13.1 0.8 1.1 9.2 0.5 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding Laminin_G_3 PF13385.6 GAX20522.1 - 1.1e-05 25.6 0.0 4.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily GDNF PF02351.16 GAX20523.1 - 0.39 11.7 4.6 0.87 10.6 4.6 1.5 1 0 0 1 1 1 0 GDNF/GAS1 domain 3Beta_HSD PF01073.19 GAX20524.1 - 2.8e-35 121.7 0.0 3.5e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAX20524.1 - 4.3e-25 88.6 0.0 8.1e-25 87.7 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAX20524.1 - 1.4e-14 53.9 0.0 1.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 GAX20524.1 - 2.6e-11 43.2 0.0 4.6e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GAX20524.1 - 2.8e-11 43.4 0.0 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX20524.1 - 1.4e-10 40.8 0.0 2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAX20524.1 - 2.9e-05 24.0 0.0 5.6e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAX20524.1 - 7.6e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 GAX20524.1 - 0.0022 17.5 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 GAX20524.1 - 0.15 11.6 0.0 2.8 7.4 0.0 2.4 2 1 0 2 2 2 0 NmrA-like family DUF2358 PF10184.9 GAX20525.1 - 3.1e-06 27.4 0.4 6.7e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) HOOK PF05622.12 GAX20526.1 - 1.2e-12 46.8 63.2 5e-11 41.5 63.8 6.5 3 1 5 8 8 8 3 HOOK protein DUF3410 PF11890.8 GAX20526.1 - 0.036 13.9 3.4 0.22 11.3 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3410) ERM PF00769.19 GAX20527.1 - 0.0069 16.2 28.0 0.0069 16.2 28.0 3.1 1 1 2 3 3 3 1 Ezrin/radixin/moesin family DUF812 PF05667.11 GAX20527.1 - 0.046 12.6 38.7 0.076 11.9 38.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) zf-HC5HC2H PF13771.6 GAX20527.1 - 0.047 14.0 3.2 0.15 12.4 3.2 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain TPR_MLP1_2 PF07926.12 GAX20527.1 - 8.5 6.4 68.3 0.23 11.5 25.7 3.4 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Med3 PF11593.8 GAX20528.1 - 0.092 11.9 2.8 0.12 11.6 2.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DEAD PF00270.29 GAX20529.1 - 1.3e-43 148.8 0.0 3.4e-43 147.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX20529.1 - 4.1e-27 94.7 0.9 1.1e-26 93.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SOBP PF15279.6 GAX20529.1 - 2.4 8.7 8.6 5.1 7.6 8.6 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein SufE PF02657.15 GAX20530.1 - 8.7e-10 38.5 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain DUF1336 PF07059.12 GAX20531.1 - 1.5e-54 185.5 0.0 2.3e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 GAX20531.1 - 3.3e-15 56.1 0.0 5.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 START domain PH PF00169.29 GAX20531.1 - 0.00043 20.7 0.4 0.0031 18.0 0.0 2.4 2 0 0 2 2 2 1 PH domain DUF4781 PF16013.5 GAX20531.1 - 0.22 10.3 0.7 0.36 9.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) SufE PF02657.15 GAX20532.1 - 6.6e-14 51.8 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain Peptidase_M23 PF01551.22 GAX20533.1 - 6.1e-17 61.6 0.0 1.6e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M23 PLAC8 PF04749.17 GAX20534.1 - 1.1e-18 68.0 13.9 1.7e-18 67.4 13.9 1.2 1 0 0 1 1 1 1 PLAC8 family FA_desaturase PF00487.24 GAX20536.1 - 9.7e-26 91.1 18.6 1.4e-25 90.6 18.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase HMG_box PF00505.19 GAX20537.1 - 9.6e-10 38.7 0.9 2.3e-09 37.5 0.9 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX20537.1 - 4.8e-07 30.3 0.7 1.5e-06 28.7 0.7 2.0 1 0 0 1 1 1 1 HMG-box domain Ret2_MD PF18528.1 GAX20537.1 - 0.15 12.4 0.1 0.51 10.7 0.2 1.8 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain NLBH PF05211.12 GAX20537.1 - 0.79 9.2 7.7 5.1 6.6 0.3 2.3 2 0 0 2 2 2 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DUF4266 PF14086.6 GAX20537.1 - 1.8 9.6 3.3 31 5.6 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Hydrolase_6 PF13344.6 GAX20538.1 - 1.2e-29 102.4 0.0 2.2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX20538.1 - 1e-20 73.6 0.0 3.2e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX20538.1 - 3.9e-09 37.1 0.1 1.3e-08 35.4 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX20538.1 - 6.2e-08 32.9 0.1 0.0014 18.7 0.0 2.7 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAX20538.1 - 0.0028 17.3 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase HSF_DNA-bind PF00447.17 GAX20539.1 - 7.1e-20 71.4 0.1 1.4e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding CYTH PF01928.21 GAX20540.1 - 1.6e-19 70.5 0.0 2.7e-19 69.8 0.0 1.4 1 1 0 1 1 1 1 CYTH domain DUF4485 PF14846.6 GAX20540.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) Acetyltransf_1 PF00583.25 GAX20542.1 - 8.2e-10 38.9 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX20542.1 - 2.6e-08 34.2 0.0 3.8e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX20542.1 - 3.3e-07 30.3 0.0 6.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX20542.1 - 4.8e-07 29.6 0.0 9.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 GAX20542.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase COX5A PF02284.16 GAX20542.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Acetyltransf_3 PF13302.7 GAX20542.1 - 0.17 12.5 0.0 0.21 12.2 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF285 PF03382.14 GAX20543.1 - 4.1e-21 75.0 2.3 4.4e-21 74.9 2.3 1.0 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 CorA PF01544.18 GAX20544.1 - 5.8e-06 25.8 0.6 1.9e-05 24.1 0.3 1.9 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein Methyltransf_28 PF02636.17 GAX20545.1 - 2.1e-60 204.6 0.1 2.9e-60 204.1 0.1 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF4129 PF13559.6 GAX20546.1 - 0.074 13.3 7.9 0.054 13.8 5.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) UVR PF02151.19 GAX20546.1 - 0.13 12.1 2.3 0.28 11.0 2.3 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif 2OG-FeII_Oxy PF03171.20 GAX20547.1 - 0.00011 22.6 0.0 0.00025 21.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MtN3_slv PF03083.16 GAX20550.1 - 1.2e-24 86.2 5.6 4.2e-17 61.9 1.4 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF2561 PF10812.8 GAX20550.1 - 0.048 13.7 0.1 1.9 8.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) WD40 PF00400.32 GAX20551.1 - 2e-10 41.1 12.1 0.011 16.6 0.1 7.1 7 1 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX20551.1 - 0.00048 20.4 0.0 0.47 10.8 0.0 3.9 4 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX20551.1 - 0.05 12.6 0.1 8 5.3 0.1 2.7 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAX20551.1 - 0.098 12.6 1.2 5 7.2 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Olduvai PF06758.13 GAX20551.1 - 0.18 12.1 1.6 0.89 9.9 1.6 2.2 1 0 0 1 1 1 0 Olduvai domain KH_1 PF00013.29 GAX20552.1 - 2.3e-11 43.4 0.0 2.3e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 GAX20552.1 - 2.4e-05 24.1 0.1 0.0036 17.2 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 GAX20552.1 - 9.3e-05 22.2 0.0 0.0048 16.7 0.0 2.3 2 0 0 2 2 2 1 KH domain DUF2530 PF10745.9 GAX20552.1 - 0.022 15.0 1.2 0.25 11.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) PPR_2 PF13041.6 GAX20557.1 - 9e-37 125.0 0.2 5.6e-08 32.9 0.0 8.7 6 2 4 10 10 10 7 PPR repeat family PPR_3 PF13812.6 GAX20557.1 - 4.4e-29 100.3 0.5 5.4e-07 29.6 0.0 7.4 5 2 2 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.20 GAX20557.1 - 2.2e-23 80.8 0.0 0.0012 19.0 0.0 9.0 10 0 0 10 10 10 5 PPR repeat PPR_1 PF12854.7 GAX20557.1 - 1.1e-10 41.0 2.1 0.25 11.1 0.3 7.7 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 GAX20557.1 - 1.6e-10 40.7 3.3 1.9e-06 27.4 0.0 3.4 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP Smr PF01713.21 GAX20557.1 - 0.00028 21.2 0.0 0.00083 19.7 0.0 1.9 1 0 0 1 1 1 1 Smr domain tRNA_synt_1c_R1 PF04558.15 GAX20557.1 - 0.012 15.6 0.6 6.8 6.7 0.0 3.9 4 0 0 4 4 4 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 HrpB1_HrpK PF09613.10 GAX20557.1 - 5.3 6.7 13.4 4.5 6.9 0.5 5.2 2 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) MFS_1 PF07690.16 GAX20558.1 - 6.1e-09 35.3 13.1 6.1e-09 35.3 13.1 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily CIAPIN1 PF05093.13 GAX20559.1 - 1.6e-14 54.2 14.4 2.2e-14 53.8 3.5 2.8 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis GMC_oxred_C PF05199.13 GAX20560.1 - 1.1e-20 74.7 0.0 1.7e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 GAX20560.1 - 3.3e-18 66.1 0.0 4.8e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FmdA_AmdA PF03069.15 GAX20561.1 - 6.7e-28 97.6 0.0 3.7e-27 95.2 0.0 1.9 1 1 0 1 1 1 1 Acetamidase/Formamidase family SET PF00856.28 GAX20562.1 - 3.2e-14 53.7 0.0 4.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 GAX20562.1 - 3.4e-11 44.0 0.3 7.9e-11 42.8 0.1 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF819 PF05684.12 GAX20563.1 - 1.1e-31 110.3 17.6 1.1e-31 110.3 17.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF819) Glt_symporter PF03616.14 GAX20563.1 - 0.0019 17.0 8.4 0.0037 16.0 8.4 1.5 1 0 0 1 1 1 1 Sodium/glutamate symporter 5_3_exonuc_N PF02739.16 GAX20564.1 - 2.6e-49 167.2 0.0 4.9e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 GAX20564.1 - 1.4e-26 92.9 0.0 3.3e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GAX20564.1 - 0.0062 17.1 0.0 0.15 12.7 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 GAX20564.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif GREB1 PF15782.5 GAX20564.1 - 2.8 5.0 13.2 4 4.4 13.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NYN_YacP PF05991.11 GAX20564.1 - 5.1 7.0 7.1 2 8.3 0.0 3.2 4 0 0 4 4 4 0 YacP-like NYN domain Guanylate_cyc PF00211.20 GAX20567.1 - 6.5e-48 162.8 0.0 1.2e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX20567.1 - 2.1e-30 106.2 0.3 5.3e-30 104.9 0.3 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Prenyltrans PF00432.21 GAX20568.1 - 7.5e-22 76.8 8.9 3.2e-05 23.6 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat HNH_3 PF13392.6 GAX20569.1 - 1.2e-07 31.3 0.2 0.0056 16.4 0.2 2.6 2 0 0 2 2 2 2 HNH endonuclease AP2 PF00847.20 GAX20569.1 - 1.8e-05 24.8 0.8 1.8e-05 24.8 0.8 2.1 2 0 0 2 2 2 1 AP2 domain Zip PF02535.22 GAX20570.1 - 3.8e-24 85.5 0.6 5.3e-24 85.1 0.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.20 GAX20570.1 - 0.79 9.2 2.9 6.2 6.3 0.1 2.4 1 1 1 2 2 2 0 E1-E2 ATPase Pro_isomerase PF00160.21 GAX20573.1 - 5.2e-11 43.1 0.0 1.7e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sec1 PF00995.23 GAX20573.1 - 0.0066 15.7 2.9 0.0087 15.3 2.9 1.1 1 0 0 1 1 1 1 Sec1 family FapA PF03961.13 GAX20573.1 - 0.042 12.5 2.6 0.058 12.0 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A IL2 PF00715.17 GAX20573.1 - 0.18 11.7 2.4 0.28 11.1 2.4 1.3 1 0 0 1 1 1 0 Interleukin 2 FlaC_arch PF05377.11 GAX20573.1 - 1.3 9.5 4.3 1.7 9.1 0.5 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pro_isomerase PF00160.21 GAX20574.1 - 4.2e-10 40.1 0.0 7.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 GAX20575.1 - 5.9e-10 39.6 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Herpes_UL6 PF01763.16 GAX20575.1 - 0.044 12.3 4.3 0.18 10.3 3.9 1.9 2 0 0 2 2 2 0 Herpesvirus UL6 like Flu_M1_C PF08289.11 GAX20575.1 - 0.062 13.5 0.8 0.14 12.4 0.2 1.8 1 1 1 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain GPHR_N PF12537.8 GAX20575.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal SOGA PF11365.8 GAX20575.1 - 0.17 13.0 4.8 0.36 12.0 4.8 1.5 1 0 0 1 1 1 0 Protein SOGA Uso1_p115_C PF04871.13 GAX20575.1 - 1.9 8.9 6.9 3.8 7.9 6.9 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region NFACT-R_1 PF05670.13 GAX20576.1 - 4.7e-32 110.9 0.0 4.7e-32 110.9 0.0 2.6 3 0 0 3 3 3 1 NFACT protein RNA binding domain FbpA PF05833.11 GAX20576.1 - 2.3e-30 105.8 19.1 4.9e-23 81.6 0.0 3.1 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 GAX20576.1 - 1e-26 92.9 0.0 1e-26 92.9 0.0 4.5 6 0 0 6 6 6 1 NFACT protein C-terminal domain Rot1 PF10681.9 GAX20576.1 - 3.3 7.2 6.1 0.52 9.8 0.8 2.4 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal DUF3437 PF11919.8 GAX20577.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) EXS PF03124.14 GAX20578.1 - 3.3e-58 197.6 16.9 3.3e-58 197.6 16.9 1.6 2 0 0 2 2 2 1 EXS family Cyclin_N PF00134.23 GAX20579.1 - 7.6e-17 61.3 1.2 1.3e-16 60.5 1.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX20579.1 - 9.8e-06 25.7 0.0 6.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain PP2C PF00481.21 GAX20581.1 - 1.4e-27 96.9 1.7 5.3e-18 65.6 0.0 4.3 4 0 0 4 4 4 4 Protein phosphatase 2C RNase_T PF00929.24 GAX20582.1 - 9.3e-10 39.3 0.0 2.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease TPR_2 PF07719.17 GAX20583.1 - 0.013 15.5 1.7 6.9 7.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX20583.1 - 0.041 13.7 4.6 8.5 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX20583.1 - 0.28 11.1 3.1 12 5.9 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20583.1 - 0.77 10.1 3.7 2.2 8.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat IQ PF00612.27 GAX20584.1 - 7.9e-29 96.7 77.0 0.007 16.1 0.2 15.2 15 0 0 15 15 15 13 IQ calmodulin-binding motif Sulfatase PF00884.23 GAX20585.1 - 3.2e-58 197.6 0.0 2.2e-56 191.5 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 GAX20585.1 - 3.4e-12 47.2 0.0 6.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 GAX20585.1 - 6.7e-07 29.2 0.5 4.7e-06 26.4 0.5 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 GAX20585.1 - 5.9e-05 21.9 0.1 7.8e-05 21.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DER1 PF04511.15 GAX20587.1 - 2.2e-18 66.9 1.9 2.7e-18 66.6 1.9 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 GAX20587.1 - 0.00022 21.3 6.8 0.00035 20.6 6.8 1.4 1 0 0 1 1 1 1 Rhomboid family Chloroa_b-bind PF00504.21 GAX20588.1 - 2.7e-29 102.8 0.1 3.8e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Fascin PF06268.13 GAX20590.1 - 0.14 12.4 0.1 0.32 11.2 0.1 1.6 1 1 0 1 1 1 0 Fascin domain Syja_N PF02383.18 GAX20592.1 - 3.8e-72 243.3 0.0 7e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain MTTB PF06253.11 GAX20593.1 - 0.25 9.3 0.3 0.34 8.8 0.3 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) CDP-OH_P_transf PF01066.21 GAX20594.1 - 2.4e-14 53.9 0.6 2.4e-14 53.9 0.6 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4267 PF14087.6 GAX20594.1 - 0.14 12.2 3.3 0.46 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) LSM PF01423.22 GAX20595.1 - 1.5e-15 56.6 0.2 1.9e-15 56.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX20595.1 - 0.00024 21.2 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2715 PF10895.8 GAX20595.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) MAPKK1_Int PF08923.10 GAX20596.1 - 1.1e-09 38.2 0.0 1.3e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting PSCyt3 PF07627.11 GAX20597.1 - 0.2 12.0 1.3 0.43 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Laminin_II PF06009.12 GAX20597.1 - 0.29 11.1 29.4 0.24 11.4 1.8 3.4 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 GAX20597.1 - 1.2 9.2 28.1 0.074 13.1 2.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) OmpH PF03938.14 GAX20597.1 - 6.4 7.1 46.9 4 7.8 10.2 4.1 3 2 1 4 4 4 0 Outer membrane protein (OmpH-like) NAD_binding_10 PF13460.6 GAX20598.1 - 1.4e-42 145.7 0.3 2e-42 145.2 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX20598.1 - 1.4e-10 41.1 0.3 2.7e-10 40.2 0.3 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAX20598.1 - 8.9e-10 38.4 0.2 2.2e-09 37.1 0.1 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX20598.1 - 8.9e-05 21.6 0.3 0.00013 21.1 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAX20598.1 - 0.0004 19.9 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase MecA_N PF05223.11 GAX20598.1 - 0.074 13.3 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain DUF1773 PF08593.10 GAX20599.1 - 3.6 8.7 5.0 3.2 8.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function MRP-L28 PF09812.9 GAX20600.1 - 0.011 15.9 2.1 0.019 15.1 2.1 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 eIF-3c_N PF05470.12 GAX20600.1 - 0.017 13.5 0.1 0.021 13.2 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HA PF03457.14 GAX20601.1 - 1.3e-46 156.7 10.4 4.4e-18 65.4 0.3 3.8 4 0 0 4 4 4 3 Helicase associated domain DUF4936 PF16290.5 GAX20601.1 - 0.0087 16.7 4.8 0.3 11.8 0.1 4.0 2 1 0 3 3 3 1 Domain of unknown function (DUF4936) DCP1 PF06058.13 GAX20601.1 - 0.034 14.1 0.6 0.4 10.6 0.0 2.9 4 0 0 4 4 4 0 Dcp1-like decapping family DUF4960 PF16324.5 GAX20601.1 - 0.038 13.5 1.3 9.5 5.7 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4960) eIF-6 PF01912.18 GAX20602.1 - 3.5e-76 255.0 0.4 6e-76 254.2 0.4 1.4 2 0 0 2 2 2 1 eIF-6 family SecA_DEAD PF07517.14 GAX20603.1 - 1.4e-111 372.5 0.3 2.6e-111 371.5 0.3 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 GAX20603.1 - 3.8e-41 141.3 4.9 3.8e-41 141.3 4.9 1.8 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 GAX20603.1 - 4.4e-27 94.9 0.0 1.8e-26 93.0 0.0 2.1 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 GAX20603.1 - 2.7e-06 27.3 0.3 1.6e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX20603.1 - 0.077 13.3 0.3 1.9 8.8 0.0 2.9 3 0 0 3 3 3 0 Helicase conserved C-terminal domain DUF1664 PF07889.12 GAX20603.1 - 0.15 12.1 1.7 0.28 11.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) C2 PF00168.30 GAX20604.1 - 3.6e-12 46.5 0.0 2.1e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 C2 domain Ctr PF04145.15 GAX20605.1 - 1.7e-15 57.9 16.8 7.5e-12 46.1 16.8 2.5 1 1 0 1 1 1 1 Ctr copper transporter family Peptidase_M50 PF02163.22 GAX20606.1 - 0.15 11.3 2.0 2.2 7.5 2.0 2.5 1 1 0 1 1 1 0 Peptidase family M50 Chloroa_b-bind PF00504.21 GAX20607.1 - 7.5e-14 52.6 1.9 2.3e-08 34.7 0.4 2.1 1 1 1 2 2 2 2 Chlorophyll A-B binding protein GTP_CH_N PF12471.8 GAX20608.1 - 1.1e-77 260.1 0.0 1.6e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 GAX20608.1 - 2.3e-14 53.3 0.0 3.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II LETM1 PF07766.13 GAX20609.1 - 2.4e-92 309.1 6.6 2.4e-92 309.1 6.6 2.6 2 1 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 GAX20609.1 - 3.8e-09 36.9 0.6 1.6e-08 34.9 0.6 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX20609.1 - 3.1e-05 23.6 0.8 0.037 14.0 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 GAX20609.1 - 6.6e-05 22.2 0.2 0.061 12.9 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 GAX20609.1 - 0.0093 15.4 2.7 0.051 13.1 0.2 3.0 3 0 0 3 3 3 1 EF hand SAP PF02037.27 GAX20609.1 - 0.0095 15.7 0.1 0.04 13.7 0.1 2.2 1 0 0 1 1 1 1 SAP domain EF-hand_8 PF13833.6 GAX20609.1 - 0.024 14.5 0.6 0.26 11.2 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAX20609.1 - 0.1 12.9 4.7 0.1 12.9 0.4 3.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_M24 PF00557.24 GAX20610.1 - 2.5e-39 135.2 0.0 3.1e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 GAX20610.1 - 0.022 14.9 9.1 0.028 14.5 9.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 GAX20610.1 - 1.5 7.0 5.8 2 6.6 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4710 PF15828.5 GAX20610.1 - 4 7.6 11.1 10 6.3 11.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) UCH PF00443.29 GAX20611.1 - 3.4e-62 210.3 0.1 6e-62 209.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX20611.1 - 4e-06 26.7 3.6 0.00056 19.6 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAX20611.1 - 0.0046 17.5 0.0 0.034 14.8 0.0 2.5 1 1 0 1 1 1 1 DUSP domain RRP36 PF06102.12 GAX20612.1 - 0.14 12.2 0.4 0.23 11.4 0.4 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF3787 PF12655.7 GAX20613.1 - 0.076 13.0 0.4 0.47 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) SET PF00856.28 GAX20615.1 - 4.1e-05 24.0 0.0 7.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 SET domain IPP-2 PF04979.14 GAX20616.1 - 8.8e-22 78.3 11.7 8.8e-22 78.3 11.7 1.7 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) PMSR PF01625.21 GAX20617.1 - 5e-48 163.2 0.1 5.8e-48 162.9 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ist1 PF03398.14 GAX20617.1 - 0.053 13.5 0.1 0.071 13.0 0.1 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway T3SS_ATPase_C PF18269.1 GAX20619.1 - 0.02 14.7 0.5 0.04 13.8 0.5 1.5 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain BRE1 PF08647.11 GAX20619.1 - 0.3 11.2 9.2 0.042 13.9 4.5 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HA PF03457.14 GAX20620.1 - 1.3e-53 179.2 21.1 9.8e-17 61.1 0.2 4.5 4 0 0 4 4 4 4 Helicase associated domain TUDOR_5 PF18359.1 GAX20620.1 - 1.1 9.0 5.6 8.9 6.1 0.4 2.7 2 1 0 2 2 2 0 Histone methyltransferase Tudor domain 1 HA PF03457.14 GAX20621.1 - 1.6e-53 178.9 21.5 8.1e-16 58.1 0.6 4.5 4 0 0 4 4 4 4 Helicase associated domain HA PF03457.14 GAX20622.1 - 2.6e-60 200.6 11.9 2e-17 63.3 0.5 4.4 4 0 0 4 4 4 4 Helicase associated domain TUDOR_5 PF18359.1 GAX20622.1 - 0.0069 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Nitroreductase PF00881.24 GAX20623.1 - 9.5e-15 55.1 0.0 1.8e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 GAX20623.1 - 8.8e-05 22.2 0.0 0.00093 18.8 0.0 2.1 2 0 0 2 2 2 1 Putative TM nitroreductase DDE_Tnp_1_7 PF13843.6 GAX20624.1 - 1.3e-11 44.4 0.1 2.4e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Transposase IS4 FAD_binding_3 PF01494.19 GAX20625.1 - 4.2e-14 52.6 1.0 5.2e-07 29.2 0.2 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX20625.1 - 8.2e-05 22.3 2.5 0.12 11.9 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAX20625.1 - 0.00035 19.9 0.1 0.00087 18.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAX20625.1 - 0.00037 19.8 0.3 0.00058 19.2 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX20625.1 - 0.0012 17.8 0.2 1.1 8.1 0.0 2.5 2 1 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 GAX20625.1 - 0.0013 18.2 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX20625.1 - 0.0018 18.3 0.1 3.5 7.6 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAX20625.1 - 0.0077 16.4 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAX20625.1 - 0.02 14.0 0.2 0.03 13.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 GAX20625.1 - 0.025 13.3 0.1 0.039 12.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 GAX20625.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAX20625.1 - 0.11 13.1 0.1 0.34 11.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_1 PF00667.20 GAX20626.1 - 5.3e-52 176.6 0.0 7.8e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX20626.1 - 1.3e-25 90.2 0.1 2.9e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAX20626.1 - 2.3e-17 63.6 0.1 6.1e-17 62.2 0.1 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAX20626.1 - 0.17 12.0 0.0 7 6.8 0.0 2.7 2 1 0 3 3 3 0 Ferric reductase NAD binding domain RPE65 PF03055.15 GAX20627.1 - 3.7e-104 349.5 0.0 4.5e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Hydrolase_4 PF12146.8 GAX20628.1 - 0.00017 20.9 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GAX20628.1 - 0.0096 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 GAX20628.1 - 0.023 14.2 0.7 0.082 12.5 0.0 1.8 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 GAX20628.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 GAX20628.1 - 0.2 10.5 0.2 0.42 9.4 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family RRM_1 PF00076.22 GAX20629.1 - 9.4e-14 51.0 0.0 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GAX20629.1 - 4e-13 48.8 31.0 2.7e-07 30.3 0.6 4.4 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 GAX20629.1 - 7.6e-06 25.6 28.6 0.022 14.5 0.5 5.3 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.6 GAX20629.1 - 0.00038 20.3 11.3 0.89 9.6 0.9 4.3 3 1 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 GAX20629.1 - 1.1 9.2 35.4 0.17 11.8 2.6 5.3 5 0 0 5 5 5 0 Zinc knuckle Rad50_zn_hook PF04423.14 GAX20629.1 - 7.6 6.5 6.4 4.5 7.2 0.1 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Mss51 PF13824.6 GAX20629.1 - 9.8 6.4 19.9 0.84 9.8 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Cofac_haem_bdg PF04187.13 GAX20630.1 - 2e-13 50.8 0.0 5.4e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 Haem-binding uptake, Tiki superfamily, ChaN Dynamin_N PF00350.23 GAX20631.1 - 5.9e-22 78.5 0.6 3.1e-11 43.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 GAX20631.1 - 1.4e-12 47.7 0.0 3.7e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX20631.1 - 1.8e-08 34.2 0.1 1.3e-06 28.1 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX20631.1 - 4.5e-06 26.7 0.2 0.0062 16.5 0.0 3.0 3 1 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 GAX20631.1 - 0.00054 19.5 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B ABC_tran PF00005.27 GAX20631.1 - 0.073 13.6 0.0 0.75 10.3 0.0 2.7 2 1 1 3 3 3 0 ABC transporter ATP_bind_1 PF03029.17 GAX20631.1 - 0.11 12.2 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 GAX20631.1 - 0.13 11.5 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 Septin CBM_6 PF03422.15 GAX20632.1 - 1.2e-36 125.8 4.3 1.1e-13 51.6 0.1 3.4 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX20632.1 - 1.3e-18 67.4 0.0 1.3e-18 67.4 0.0 2.0 1 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX20632.1 - 2e-13 50.4 4.9 3.7e-07 30.3 0.0 3.7 3 0 0 3 3 3 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX20632.1 - 5.6e-10 39.5 3.6 0.0034 17.6 0.1 3.7 3 0 0 3 3 3 3 Carbohydrate binding module (family 35) Y_Y_Y PF07495.13 GAX20632.1 - 0.015 15.2 0.1 24 5.0 0.0 4.0 4 0 0 4 4 4 0 Y_Y_Y domain Iron_transport PF10634.9 GAX20632.1 - 0.017 15.3 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Fe2+ transport protein Peptidase_M43 PF05572.13 GAX20633.1 - 4.5e-14 52.6 0.0 7.6e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX20633.1 - 0.0004 20.6 0.1 0.00062 20.0 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX20633.1 - 0.004 16.8 0.0 0.011 15.4 0.0 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX20633.1 - 0.011 16.3 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 GAX20634.1 - 1.3e-26 93.4 0.2 1e-13 51.4 0.0 2.6 2 1 0 2 2 2 2 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX20634.1 - 5.2e-10 39.8 4.0 0.00011 22.4 0.1 2.4 2 1 0 2 2 2 2 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX20634.1 - 6.1e-10 39.7 1.0 0.00016 22.2 0.1 2.3 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX20634.1 - 2.3e-05 24.1 5.1 0.11 12.1 0.1 2.9 2 1 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 GAX20634.1 - 0.0001 22.0 0.1 0.33 10.5 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.6 GAX20634.1 - 0.0011 18.9 0.5 0.84 9.5 0.1 2.4 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX20634.1 - 0.002 18.0 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 2 Matrixin Peptidase_M48 PF01435.18 GAX20634.1 - 0.0079 16.0 0.3 1.2 8.9 0.1 2.2 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M7 PF02031.16 GAX20634.1 - 0.014 15.5 0.4 4.8 7.3 0.1 2.6 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family DUF551 PF04448.12 GAX20634.1 - 0.051 14.5 0.1 18 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF551) SprT-like PF10263.9 GAX20634.1 - 0.17 11.7 0.1 24 4.8 0.0 2.5 2 0 0 2 2 2 0 SprT-like family Metallopep PF12044.8 GAX20634.1 - 2.2 6.8 4.5 12 4.4 0.3 2.1 2 0 0 2 2 2 0 Putative peptidase family PIN_8 PF18476.1 GAX20635.1 - 0.085 12.7 3.2 0.088 12.6 3.2 1.0 1 0 0 1 1 1 0 PIN like domain PPP1R35_C PF15503.6 GAX20635.1 - 2.1 8.2 6.2 2.8 7.8 1.1 2.1 1 1 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus ATP_bind_3 PF01171.20 GAX20637.1 - 1.1e-35 123.1 0.0 2.3e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 PP-loop family DUF924 PF06041.11 GAX20637.1 - 3.3e-11 43.6 2.9 6.9e-11 42.6 2.9 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Asn_synthase PF00733.21 GAX20637.1 - 2.9e-05 23.9 0.0 7.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 GAX20637.1 - 8.9e-05 22.1 0.0 0.008 15.7 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 GAX20637.1 - 0.00031 19.9 0.0 0.00065 18.9 0.0 1.5 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 GAX20637.1 - 0.0043 15.9 0.0 0.0075 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Glyco_hydro_38N PF01074.22 GAX20637.1 - 0.02 14.3 3.0 0.063 12.6 3.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain TPP_enzyme_M_2 PF16582.5 GAX20637.1 - 0.059 13.1 2.2 0.88 9.2 1.6 2.5 2 0 0 2 2 2 0 Middle domain of thiamine pyrophosphate DUF4130 PF13566.6 GAX20637.1 - 0.29 11.2 2.2 5 7.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4130 PDZ_6 PF17820.1 GAX20638.1 - 1.5e-12 47.1 0.1 3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 GAX20638.1 - 3.2e-10 40.2 0.0 0.00023 21.4 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 GAX20638.1 - 4e-09 36.7 0.2 0.00026 21.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 GAX20638.1 - 0.00018 21.4 0.1 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain Ribosomal_S17 PF00366.20 GAX20638.1 - 0.061 13.4 0.1 2.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein S17 PK_C PF02887.16 GAX20638.1 - 0.15 12.3 0.3 0.52 10.5 0.2 1.9 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain AAA PF00004.29 GAX20639.1 - 3.6e-14 53.3 0.0 8.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX20639.1 - 9.8e-05 22.6 0.1 0.0014 18.9 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 GAX20639.1 - 0.00012 22.5 2.2 0.00034 21.0 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAX20639.1 - 0.00028 20.9 0.0 0.00073 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAX20639.1 - 0.0019 18.0 0.1 0.078 12.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAX20639.1 - 0.0025 17.2 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX20639.1 - 0.016 15.3 0.0 0.24 11.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 GAX20639.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 GAX20639.1 - 0.03 14.1 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX20639.1 - 0.045 14.3 0.0 0.84 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAX20639.1 - 0.072 13.4 0.1 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAX20639.1 - 0.1 13.1 0.3 0.49 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX20639.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_2 PF07724.14 GAX20639.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 GAX20639.1 - 0.15 12.0 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain FKBP_C PF00254.28 GAX20640.1 - 7.4e-25 87.1 0.0 1.1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 GAX20640.1 - 1.9e-06 28.7 0.1 5e-06 27.4 0.1 1.6 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TRAM_LAG1_CLN8 PF03798.16 GAX20641.1 - 6.7e-15 55.3 16.9 6.7e-15 55.3 16.9 1.4 1 1 0 1 1 1 1 TLC domain GST_N_3 PF13417.6 GAX20642.1 - 3.1e-06 27.5 0.1 1e-05 25.9 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX20642.1 - 9.4e-06 25.6 0.1 1.5e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX20642.1 - 0.00066 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX20642.1 - 0.0017 18.5 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAX20642.1 - 0.0031 17.8 0.0 0.0074 16.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX20642.1 - 0.037 14.4 0.0 0.093 13.1 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_M14 PF00246.24 GAX20643.1 - 5.9e-12 46.0 0.9 2.9e-11 43.7 0.9 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.8 GAX20643.1 - 0.008 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 GAX20643.1 - 0.014 14.5 0.7 3 6.8 0.0 2.2 1 1 1 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family AAA_2 PF07724.14 GAX20645.1 - 8.5e-51 172.5 0.0 1.5e-48 165.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAX20645.1 - 6e-34 116.1 2.3 6e-34 116.1 2.3 3.1 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 GAX20645.1 - 1.9e-25 89.8 0.0 2.3e-13 50.7 0.0 3.3 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAX20645.1 - 1.2e-17 63.7 0.0 6.8e-17 61.3 0.0 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAX20645.1 - 4e-16 59.3 2.1 9.2e-10 38.7 0.0 4.0 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX20645.1 - 6.4e-12 46.2 11.8 9.8e-07 29.3 0.1 5.9 4 2 2 6 6 6 2 AAA ATPase domain AAA_22 PF13401.6 GAX20645.1 - 9.7e-11 42.1 0.7 0.003 17.8 0.0 4.8 3 2 2 5 5 4 2 AAA domain Clp_N PF02861.20 GAX20645.1 - 1.4e-09 38.0 3.7 0.00033 20.7 1.5 3.6 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 GAX20645.1 - 3.5e-08 33.3 0.0 2.4e-05 24.1 0.0 2.9 2 2 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 GAX20645.1 - 9.1e-08 31.7 0.1 0.00026 20.5 0.1 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 GAX20645.1 - 1.2e-07 31.8 0.0 0.0053 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAX20645.1 - 2.5e-07 30.4 0.0 0.011 15.3 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAX20645.1 - 1.2e-06 28.4 0.0 0.0055 16.4 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 GAX20645.1 - 1.6e-06 28.5 0.2 0.026 14.8 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAX20645.1 - 8.3e-06 25.7 0.1 0.0026 17.5 0.2 3.2 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 GAX20645.1 - 3.1e-05 24.5 0.0 0.73 10.4 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 GAX20645.1 - 3.8e-05 23.6 0.0 0.0066 16.3 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 GAX20645.1 - 8.1e-05 22.6 5.7 0.69 9.8 0.1 4.5 3 2 1 4 4 3 2 ATPase domain predominantly from Archaea Roc PF08477.13 GAX20645.1 - 0.00013 22.2 0.0 0.62 10.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 GAX20645.1 - 0.00024 20.6 0.1 2.7 7.3 0.0 3.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 GAX20645.1 - 0.00026 20.9 0.1 3.5 7.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAX20645.1 - 0.00034 20.3 1.0 0.0034 17.0 0.1 2.9 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 GAX20645.1 - 0.0004 20.4 0.0 0.46 10.5 0.0 3.0 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAX20645.1 - 0.00044 20.4 0.0 2.7 8.1 0.0 3.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAX20645.1 - 0.00047 20.1 0.0 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 GAX20645.1 - 0.00051 19.8 1.0 2.8 7.7 0.0 4.1 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAX20645.1 - 0.00055 20.3 0.1 2.7 8.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase DUF815 PF05673.13 GAX20645.1 - 0.0006 19.1 0.0 0.15 11.2 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GAX20645.1 - 0.0011 18.9 0.1 2.4 8.0 0.0 3.2 2 1 1 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 GAX20645.1 - 0.0015 19.1 2.8 2.4 8.7 0.0 3.9 3 2 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.12 GAX20645.1 - 0.0023 17.3 0.0 1.6 8.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 GAX20645.1 - 0.0025 18.1 0.3 0.2 12.0 0.1 3.3 3 1 0 3 3 2 1 AAA domain ResIII PF04851.15 GAX20645.1 - 0.011 15.7 0.0 7.9 6.4 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 GAX20645.1 - 0.015 14.4 0.0 0.06 12.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 GAX20645.1 - 0.021 14.6 0.2 12 5.8 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain Torsin PF06309.11 GAX20645.1 - 0.028 14.5 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Torsin SpoVR PF04293.13 GAX20645.1 - 0.031 13.0 0.6 0.064 11.9 0.6 1.4 1 0 0 1 1 1 0 SpoVR like protein AAA_24 PF13479.6 GAX20645.1 - 0.042 13.6 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAX20645.1 - 0.047 12.9 0.0 5.8 6.0 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain APC_N_CC PF16689.5 GAX20645.1 - 0.067 13.3 1.5 0.24 11.5 1.5 2.0 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Ran-binding PF05508.11 GAX20645.1 - 0.12 11.4 4.6 0.048 12.6 1.3 2.0 2 0 0 2 2 2 0 RanGTP-binding protein MMR_HSR1 PF01926.23 GAX20645.1 - 0.14 12.2 0.0 22 5.1 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 GAX20645.1 - 0.18 11.8 6.7 0.31 11.1 0.0 3.6 3 1 0 3 3 3 0 Helicase HerA, central domain BLACT_WH PF17778.1 GAX20645.1 - 0.2 11.7 1.2 1.5 8.9 0.1 2.7 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Spc7 PF08317.11 GAX20645.1 - 0.27 10.1 11.2 0.5 9.2 11.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CorA PF01544.18 GAX20645.1 - 0.42 9.9 3.7 0.95 8.7 3.7 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V-SNARE PF05008.15 GAX20645.1 - 0.52 10.7 6.0 0.87 10.0 4.2 2.4 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus YlqD PF11068.8 GAX20645.1 - 0.87 10.0 13.0 0.17 12.2 6.4 2.4 1 1 1 2 2 2 0 YlqD protein AAA_11 PF13086.6 GAX20645.1 - 2.3 8.0 9.3 2.9 7.6 0.0 3.6 3 1 0 3 3 2 0 AAA domain AAA_23 PF13476.6 GAX20645.1 - 3.2 8.2 25.5 3.2 8.2 0.0 4.6 3 2 2 5 5 2 0 AAA domain V_ATPase_I PF01496.19 GAX20645.1 - 6.3 4.6 5.6 9.1 4.1 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DSPc PF00782.20 GAX20646.1 - 0.066 13.0 0.4 5.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain ALS2CR11 PF15729.5 GAX20647.1 - 0.13 11.4 0.5 0.22 10.6 0.5 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 AAA_2 PF07724.14 GAX20648.1 - 1.8e-48 164.9 0.0 1.4e-46 158.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAX20648.1 - 7e-26 90.2 5.7 1.2e-25 89.4 3.6 2.4 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 GAX20648.1 - 5.4e-22 78.6 0.0 1.1e-10 42.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAX20648.1 - 4.7e-19 68.2 0.1 2.1e-18 66.1 0.0 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAX20648.1 - 1.5e-14 54.2 0.0 3.9e-09 36.6 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX20648.1 - 3.4e-13 50.3 1.8 1.1e-06 29.2 0.3 4.6 3 1 0 3 3 3 2 AAA ATPase domain Clp_N PF02861.20 GAX20648.1 - 1.3e-09 38.1 0.6 0.00033 20.7 0.0 3.4 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 GAX20648.1 - 2e-09 37.8 0.1 0.004 17.4 0.0 3.8 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 GAX20648.1 - 8.1e-08 32.4 0.0 0.0072 16.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain TniB PF05621.11 GAX20648.1 - 1.7e-07 30.8 0.0 0.00023 20.7 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 GAX20648.1 - 4.5e-07 29.7 0.0 0.00034 20.4 0.0 3.2 2 2 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 GAX20648.1 - 1.2e-06 28.7 0.2 0.81 9.6 0.0 4.3 2 2 1 4 4 4 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 GAX20648.1 - 2.2e-06 27.3 0.0 0.028 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 GAX20648.1 - 4.4e-05 23.7 0.0 0.35 11.1 0.0 3.1 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 GAX20648.1 - 0.00025 20.8 0.0 0.94 9.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAX20648.1 - 0.00034 20.1 0.0 2.2 7.6 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAX20648.1 - 0.00047 19.9 0.1 0.45 10.2 0.1 3.5 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX20648.1 - 0.00054 20.5 0.6 0.61 10.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 GAX20648.1 - 0.00072 19.6 0.0 0.65 10.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 GAX20648.1 - 0.00074 19.4 0.0 0.049 13.5 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAX20648.1 - 0.00089 19.6 0.0 2.3 8.7 0.0 3.1 3 0 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 GAX20648.1 - 0.0011 18.9 0.1 2.1 8.2 0.0 3.6 3 0 0 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 GAX20648.1 - 0.0019 18.5 0.0 0.63 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX20648.1 - 0.0019 18.3 0.1 2 8.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 GAX20648.1 - 0.0037 17.6 0.0 0.14 12.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAX20648.1 - 0.0042 17.6 0.2 2 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.12 GAX20648.1 - 0.0052 16.7 0.0 1.7 8.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 GAX20648.1 - 0.009 15.8 1.6 3.5 7.3 0.0 3.8 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 GAX20648.1 - 0.0093 15.3 0.0 3.7 6.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 GAX20648.1 - 0.011 15.5 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.15 GAX20648.1 - 0.017 15.1 0.0 3.1 7.8 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 GAX20648.1 - 0.018 14.6 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX20648.1 - 0.039 13.7 0.0 4.3 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 GAX20648.1 - 0.044 12.8 0.0 0.23 10.5 0.0 2.2 2 1 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 GAX20648.1 - 0.13 12.3 1.0 0.82 9.7 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Acetyltransf_18 PF18014.1 GAX20648.1 - 0.14 12.0 0.0 20 5.0 0.0 3.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain AAA_11 PF13086.6 GAX20648.1 - 0.3 10.9 3.6 2.8 7.7 0.0 3.8 2 1 1 4 4 4 0 AAA domain ABC_tran_CTD PF16326.5 GAX20648.1 - 3.6 7.9 8.8 0.19 12.0 1.8 2.5 3 0 0 3 3 1 0 ABC transporter C-terminal domain AAA_23 PF13476.6 GAX20648.1 - 5.5 7.4 11.4 14 6.1 0.0 4.3 2 1 0 2 2 1 0 AAA domain CDC37_M PF08565.11 GAX20650.1 - 1.7e-22 79.6 2.8 1.7e-22 79.6 2.8 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 GAX20650.1 - 5.4e-12 45.7 0.0 5.4e-12 45.7 0.0 3.3 3 1 0 3 3 3 1 Cdc37 C terminal domain CDC37_N PF03234.14 GAX20650.1 - 7.5e-11 43.1 25.0 7.5e-11 43.1 25.0 3.1 2 2 0 2 2 2 1 Cdc37 N terminal kinase binding Cwf_Cwc_15 PF04889.12 GAX20650.1 - 0.00083 19.2 25.9 0.00083 19.2 25.9 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF4407 PF14362.6 GAX20650.1 - 7 5.9 14.0 2.6 7.3 9.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Homeobox_KN PF05920.11 GAX20651.1 - 2.9e-10 39.9 0.1 9e-10 38.3 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAX20651.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 GAX20651.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT TPR_1 PF00515.28 GAX20653.1 - 7.4e-21 73.0 30.4 9.8e-05 22.0 0.0 7.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX20653.1 - 1.3e-17 62.4 39.7 0.00011 22.0 0.2 9.1 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 GAX20653.1 - 1.4e-17 62.9 25.1 0.009 16.8 0.0 9.7 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAX20653.1 - 7.4e-17 61.6 20.3 0.03 14.8 0.1 7.6 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20653.1 - 1e-16 59.7 25.3 3.4e-05 23.7 0.0 7.4 8 0 0 8 8 6 4 Tetratricopeptide repeat ANAPC8 PF04049.13 GAX20653.1 - 2.1e-15 57.0 0.0 5.7e-13 49.1 0.0 3.0 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.6 GAX20653.1 - 5e-13 48.5 15.8 1.2e-07 31.2 0.1 6.3 4 3 3 7 7 7 4 TPR repeat TPR_17 PF13431.6 GAX20653.1 - 1.2e-11 44.1 15.6 0.017 15.5 0.1 8.3 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX20653.1 - 1.5e-10 40.3 19.6 0.0058 16.6 0.1 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX20653.1 - 3.7e-08 33.9 36.5 0.00082 20.0 0.2 8.4 6 2 3 9 9 8 2 Tetratricopeptide repeat ChAPs PF09295.10 GAX20653.1 - 8.5e-06 25.0 0.6 0.0001 21.5 0.1 2.5 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 GAX20653.1 - 9.2e-06 25.9 35.9 3.3e-05 24.1 3.9 7.5 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX20653.1 - 1.4e-05 25.4 29.8 6.7 7.6 0.1 9.4 9 1 0 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX20653.1 - 0.00032 20.9 17.5 2.1 8.6 0.3 5.8 4 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 GAX20653.1 - 0.013 15.8 4.7 2.9 8.3 0.6 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX20653.1 - 0.023 14.8 18.8 0.27 11.4 2.5 5.2 5 1 1 7 7 6 0 Tetratricopeptide repeat CCP_MauG PF03150.14 GAX20653.1 - 0.039 14.6 3.2 0.65 10.6 0.2 3.3 4 0 0 4 4 3 0 Di-haem cytochrome c peroxidase Fis1_TPR_C PF14853.6 GAX20653.1 - 0.077 13.1 4.5 1.1 9.3 0.0 3.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 GAX20653.1 - 0.13 12.7 8.7 1.2 9.6 1.3 3.7 2 1 1 3 3 3 0 Bacterial transcriptional activator domain DUF2225 PF09986.9 GAX20653.1 - 0.21 11.3 5.6 0.18 11.5 0.2 2.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.12 GAX20653.1 - 0.28 11.9 0.0 0.28 11.9 0.0 3.7 5 0 0 5 5 2 0 Sel1 repeat TPR_10 PF13374.6 GAX20653.1 - 1 9.3 26.0 1.3 9.0 0.3 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAX20653.1 - 1.2 9.2 4.5 1.6 8.8 0.4 2.9 2 1 1 3 3 2 0 Domain of Unknown Function (DUF3856) ESCRT-II PF05871.12 GAX20654.1 - 7.5e-43 146.1 0.0 9.2e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit SNARE PF05739.19 GAX20655.1 - 0.13 12.3 5.1 4.9 7.2 0.2 3.6 2 1 1 3 3 3 0 SNARE domain DUF4600 PF15372.6 GAX20655.1 - 0.2 12.1 16.7 0.24 11.8 4.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Apolipoprotein PF01442.18 GAX20655.1 - 0.45 10.4 24.5 2.5 7.9 4.1 2.0 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF45 PF01863.17 GAX20655.1 - 0.82 9.7 8.6 0.8 9.7 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF45 Styelin PF17562.2 GAX20655.1 - 1.2 9.5 4.4 2.1 8.7 0.1 2.6 2 0 0 2 2 2 0 Styelin DUF4606 PF15379.6 GAX20655.1 - 2.4 8.5 7.6 0.18 12.1 1.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4606) Lectin_N PF03954.14 GAX20655.1 - 3.8 7.3 6.0 4.4 7.0 2.3 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Arc_PepC_II PF06847.11 GAX20655.1 - 4.6 7.8 7.0 0.84 10.2 0.7 2.5 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II DUF2120 PF09893.9 GAX20655.1 - 5 7.2 19.6 0.13 12.4 10.2 2.4 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) TDRP PF15683.5 GAX20656.1 - 0.014 15.4 0.8 0.014 15.4 0.8 2.5 2 1 1 3 3 3 0 Testis development-related protein Frataxin_Cyay PF01491.16 GAX20657.1 - 2.6e-32 111.1 0.0 3.1e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Spore_II_R PF09551.10 GAX20657.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Mitofilin PF09731.9 GAX20659.1 - 1.2e-35 123.5 27.5 1.3e-35 123.4 26.9 1.4 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF1192 PF06698.11 GAX20659.1 - 0.016 15.3 0.1 0.016 15.3 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) SlyX PF04102.12 GAX20659.1 - 0.2 12.3 5.4 0.66 10.6 4.0 2.6 1 1 0 1 1 1 0 SlyX Baculo_PEP_C PF04513.12 GAX20659.1 - 1 9.4 6.1 6.7 6.8 5.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5585 PF17823.1 GAX20659.1 - 2.3 7.1 11.0 0.64 8.9 5.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5585) FAD-SLDH PF12318.8 GAX20659.1 - 4.2 7.4 6.4 3.4 7.7 3.2 2.4 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase MFS_MOT1 PF16983.5 GAX20660.1 - 5.3e-56 187.8 29.8 7.3e-30 103.6 4.3 4.0 4 0 0 4 4 4 3 Molybdate transporter of MFS superfamily Cation_ATPase_C PF00689.21 GAX20661.1 - 4.6e-40 137.3 0.3 4.6e-40 137.3 0.3 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAX20661.1 - 3.3e-37 127.8 3.0 3.3e-37 127.8 3.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAX20661.1 - 2.8e-23 83.3 0.0 1.4e-16 61.5 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX20661.1 - 6.5e-20 71.0 0.0 1.3e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAX20661.1 - 3e-17 62.0 0.5 2.3e-16 59.3 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX20661.1 - 6.9e-06 26.0 4.7 0.0023 17.7 1.7 3.2 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 GAX20661.1 - 0.0022 18.1 0.0 0.098 12.8 0.0 2.4 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 HAD PF12710.7 GAX20661.1 - 0.02 15.3 0.1 0.19 12.1 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase CobT PF06213.12 GAX20662.1 - 6.9 6.0 16.9 7.2 5.9 16.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT His_Phos_2 PF00328.22 GAX20663.1 - 1.7e-20 73.8 1.2 3.6e-19 69.4 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) KIAA1430 PF13879.6 GAX20663.1 - 0.04 14.7 0.1 0.04 14.7 0.1 1.7 2 0 0 2 2 2 0 KIAA1430 homologue YgaB PF14182.6 GAX20663.1 - 0.14 12.6 0.2 0.27 11.6 0.2 1.4 1 0 0 1 1 1 0 YgaB-like protein DIOX_N PF14226.6 GAX20664.1 - 6.6e-26 91.4 0.0 9.9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAX20664.1 - 5.1e-22 78.3 0.0 9.9e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COPIIcoated_ERV PF07970.12 GAX20665.1 - 1.9e-30 106.4 0.8 3.3e-30 105.6 0.8 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX20665.1 - 1.3e-25 89.6 0.5 2.6e-25 88.6 0.5 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 GAX20665.1 - 1.4e-20 73.2 0.1 4.7e-20 71.5 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin PRIMA1 PF16101.5 GAX20666.1 - 0.74 9.9 10.1 2.6 8.1 10.1 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TFIID-31kDa PF02291.15 GAX20667.1 - 7.9e-17 61.5 0.0 1.9e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit NAM-associated PF14303.6 GAX20667.1 - 0.013 16.2 12.4 0.013 16.2 12.4 3.0 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain Transposase_28 PF04195.12 GAX20667.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative gypsy type transposon FUN14 PF04930.15 GAX20668.1 - 2e-23 82.6 2.5 2.5e-23 82.3 2.5 1.1 1 0 0 1 1 1 1 FUN14 family EF-hand_1 PF00036.32 GAX20668.1 - 0.00049 19.4 0.0 0.00091 18.6 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 GAX20668.1 - 0.0024 17.3 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX20668.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF5320 PF17253.2 GAX20668.1 - 0.046 14.8 0.0 0.075 14.1 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5320) PPR PF01535.20 GAX20669.1 - 2.3e-05 24.3 0.3 0.0039 17.3 0.0 3.5 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 GAX20669.1 - 9.8e-05 22.5 0.3 3.9 7.8 0.0 4.0 3 1 1 4 4 4 2 PPR repeat family PPR_1 PF12854.7 GAX20669.1 - 0.011 15.4 0.0 2.8 7.7 0.0 3.6 4 0 0 4 4 4 0 PPR repeat Chalcone_3 PF16036.5 GAX20670.1 - 2e-06 28.0 0.0 3.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 GAX20670.1 - 0.0079 15.6 0.0 1.2 8.5 0.0 2.7 2 1 0 2 2 2 1 Chalcone-flavanone isomerase Chalcone_2 PF16035.5 GAX20670.1 - 0.038 13.8 0.2 3.6 7.3 0.3 2.6 1 1 1 2 2 2 0 Chalcone isomerase like UCH PF00443.29 GAX20671.1 - 4e-12 46.2 0.0 5.2e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PolyA_pol_arg_C PF12626.7 GAX20671.1 - 0.0025 17.9 0.2 0.0076 16.3 0.1 1.8 2 0 0 2 2 2 1 Polymerase A arginine-rich C-terminus CENP-H PF05837.12 GAX20671.1 - 0.052 14.0 0.5 0.052 14.0 0.5 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) RNA_POL_M_15KD PF02150.16 GAX20671.1 - 0.24 11.3 1.9 14 5.6 0.2 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit LRV_FeS PF05484.11 GAX20671.1 - 0.32 11.0 4.8 0.65 10.0 0.9 2.5 2 0 0 2 2 2 0 LRV protein FeS4 cluster Ank_2 PF12796.7 GAX20672.1 - 7.2e-10 39.3 0.2 0.00027 21.5 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX20672.1 - 7.9e-09 35.6 1.9 0.00082 19.6 0.0 4.8 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX20672.1 - 2.6e-08 34.2 1.2 0.093 13.3 0.0 4.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX20672.1 - 6.2e-05 23.1 1.3 7.3 7.5 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 GAX20672.1 - 0.013 16.0 5.4 15 6.2 0.0 5.1 6 0 0 6 6 6 0 Ankyrin repeat Rubis-subs-bind PF09273.11 GAX20673.1 - 0.086 13.5 0.3 0.19 12.4 0.3 1.7 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding GFO_IDH_MocA PF01408.22 GAX20674.1 - 3.8e-27 95.5 0.4 6.2e-27 94.8 0.4 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAX20674.1 - 3.2e-06 27.1 0.0 6.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 GAX20674.1 - 1.4e-05 25.4 0.1 3.7e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 GAX20674.1 - 0.00068 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 GAX20674.1 - 0.0074 16.9 0.1 0.013 16.2 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX20674.1 - 0.0088 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX20674.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 GAX20674.1 - 0.05 13.7 0.1 0.3 11.2 0.1 2.0 1 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NeuB PF03102.14 GAX20674.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 NeuB family Gp_dh_N PF00044.24 GAX20674.1 - 0.15 12.4 0.1 0.35 11.3 0.1 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain G-alpha PF00503.20 GAX20675.1 - 6.1e-13 48.6 0.0 8.7e-13 48.1 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit YfdX PF10938.8 GAX20675.1 - 0.036 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 YfdX protein Sec66 PF09802.9 GAX20676.1 - 0.081 12.5 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 DUF702 PF05142.12 GAX20678.1 - 1.4 9.4 6.0 8 6.9 6.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Peptidase_M4_C PF02868.15 GAX20679.1 - 0.098 12.5 0.2 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain RuvA_C PF07499.13 GAX20679.1 - 0.1 13.0 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain Chloroa_b-bind PF00504.21 GAX20681.1 - 1.6e-25 90.5 0.6 2.4e-25 89.9 0.0 1.5 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Tho2 PF11262.8 GAX20681.1 - 0.47 9.6 2.9 0.69 9.1 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GET2 PF08690.10 GAX20681.1 - 5.7 6.5 11.0 12 5.5 11.0 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 Nop14 PF04147.12 GAX20681.1 - 9.9 4.2 17.1 13 3.8 17.1 1.0 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L19e PF01280.20 GAX20682.1 - 1.8e-36 125.3 8.6 1.8e-36 125.3 8.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e COX4 PF02936.14 GAX20683.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV LRR_6 PF13516.6 GAX20684.1 - 0.14 12.2 0.1 0.46 10.7 0.1 1.9 1 0 0 1 1 1 0 Leucine Rich repeat DUF4140 PF13600.6 GAX20685.1 - 2.9 8.4 6.2 2.1 8.9 0.8 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FliT PF05400.13 GAX20686.1 - 0.014 16.2 2.6 0.014 16.2 2.6 2.9 3 0 0 3 3 3 0 Flagellar protein FliT RskA PF10099.9 GAX20686.1 - 0.03 14.6 3.5 0.048 14.0 3.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Alpha-E PF04168.12 GAX20686.1 - 0.13 12.1 1.0 0.28 10.9 1.0 1.5 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Baculo_PEP_C PF04513.12 GAX20686.1 - 0.14 12.2 4.8 0.34 11.0 4.8 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med3 PF11593.8 GAX20686.1 - 0.62 9.2 11.8 0.08 12.1 5.4 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Fzo_mitofusin PF04799.13 GAX20686.1 - 1.7 8.2 8.6 5.5 6.5 0.2 2.9 2 1 1 3 3 3 0 fzo-like conserved region HSCB_C PF07743.13 GAX20686.1 - 1.9 9.0 7.9 11 6.6 7.9 2.3 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Pkinase PF00069.25 GAX20688.1 - 3.7e-10 39.6 0.0 6.9e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX20688.1 - 2.2e-07 30.4 0.0 4.7e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Sigma70_ner PF04546.13 GAX20689.1 - 0.00011 22.1 1.2 0.00016 21.6 1.2 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Atg14 PF10186.9 GAX20689.1 - 0.013 14.7 5.6 0.016 14.3 5.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 GAX20689.1 - 0.054 13.8 11.6 0.094 13.0 11.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Herpes_U5 PF05999.11 GAX20689.1 - 0.062 12.0 0.0 0.17 10.6 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus U5-like family SgrT PF15894.5 GAX20689.1 - 0.11 12.5 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT Tho2 PF11262.8 GAX20689.1 - 0.31 10.2 7.4 0.47 9.6 7.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 BBP1_N PF15271.6 GAX20689.1 - 0.42 11.4 7.8 0.63 10.8 7.8 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein DUF4407 PF14362.6 GAX20689.1 - 2.1 7.7 6.8 3.3 7.0 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ras PF00071.22 GAX20690.1 - 4.6e-49 166.1 0.0 5.4e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX20690.1 - 2.3e-31 108.5 0.0 3.5e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX20690.1 - 2.5e-11 43.3 0.0 3.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX20690.1 - 6.1e-07 29.5 0.0 8.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX20690.1 - 0.00033 21.1 0.0 0.00067 20.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 GAX20690.1 - 0.00057 19.5 0.0 0.0093 15.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX20690.1 - 0.00072 19.5 0.2 0.0047 16.8 0.3 1.9 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 GAX20690.1 - 0.00093 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAX20690.1 - 0.011 15.5 0.1 0.036 13.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAX20690.1 - 0.011 15.6 0.0 0.16 11.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 GAX20690.1 - 0.02 14.9 0.1 0.052 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX20690.1 - 0.021 15.1 0.1 0.058 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 GAX20690.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein AAA_23 PF13476.6 GAX20690.1 - 0.022 15.3 0.0 0.053 14.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX20690.1 - 0.059 13.9 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 GAX20690.1 - 0.078 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 GAX20690.1 - 0.096 11.8 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Gtr1_RagA PF04670.12 GAX20690.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MCM PF00493.23 GAX20690.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain PT PF04886.12 GAX20691.1 - 0.024 14.2 10.1 0.039 13.5 10.1 1.3 1 0 0 1 1 1 0 PT repeat GDA1_CD39 PF01150.17 GAX20692.1 - 2.1e-66 224.4 0.0 2.7e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pkinase PF00069.25 GAX20693.1 - 8.2e-18 64.7 0.0 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SET PF00856.28 GAX20693.1 - 5.7e-16 59.4 0.0 3.3e-14 53.6 0.0 3.1 3 0 0 3 3 3 1 SET domain Cyclin_N PF00134.23 GAX20693.1 - 0.00011 21.9 0.2 0.00024 20.8 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Guanylate_cyc PF00211.20 GAX20694.1 - 1.2e-53 181.5 0.0 2.1e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 GAX20694.1 - 2.9e-33 115.1 0.0 5e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 GAX20694.1 - 1.7e-19 70.2 0.5 2.8e-09 36.7 0.6 2.4 1 1 1 2 2 2 2 Heme NO binding associated NAD_kinase PF01513.21 GAX20695.1 - 2.9e-49 167.8 0.0 1.4e-37 129.5 0.0 2.4 2 0 0 2 2 2 2 ATP-NAD kinase CRAL_TRIO PF00650.20 GAX20698.1 - 4.4e-31 107.8 0.1 5.6e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX20698.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PqiA PF04403.13 GAX20699.1 - 7.6e-07 29.1 16.5 0.00025 20.9 1.1 3.0 3 0 0 3 3 3 2 Paraquat-inducible protein A LBP_BPI_CETP PF01273.25 GAX20699.1 - 5.3e-05 22.9 0.7 0.00018 21.1 0.7 1.9 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain HTH_ABP1_N PF18107.1 GAX20700.1 - 0.077 12.7 0.2 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain YL1 PF05764.13 GAX20700.1 - 1.9 8.6 13.0 0.061 13.4 4.9 2.0 2 0 0 2 2 2 0 YL1 nuclear protein U3_assoc_6 PF08640.11 GAX20701.1 - 8e-19 67.5 8.0 2.8e-18 65.8 8.0 2.0 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 GAX20701.1 - 2.7e-08 34.0 9.3 0.0054 17.4 0.3 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX20701.1 - 0.0043 17.5 7.6 27 5.4 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TLP-20 PF06088.11 GAX20701.1 - 0.1 12.5 7.1 0.035 14.0 3.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CENP-B_dimeris PF09026.10 GAX20701.1 - 0.25 11.8 3.7 0.93 9.9 3.7 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NEMP PF10225.9 GAX20701.1 - 0.48 10.1 2.1 22 4.6 0.0 3.1 3 0 0 3 3 3 0 NEMP family Adaptin_binding PF10199.9 GAX20701.1 - 0.92 10.1 11.5 0.51 11.0 1.3 2.8 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 LRR_6 PF13516.6 GAX20702.1 - 9.3e-15 53.4 0.7 0.05 13.7 0.0 7.2 7 0 0 7 7 7 5 Leucine Rich repeat LRR_8 PF13855.6 GAX20702.1 - 9.4e-10 38.1 6.3 0.0056 16.4 0.1 5.4 5 1 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 GAX20702.1 - 3.2e-08 33.7 5.6 0.018 15.5 0.1 5.8 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX20702.1 - 2.4e-05 24.3 0.7 22 6.1 0.0 6.0 6 0 0 6 6 6 1 Leucine Rich Repeat 2OG-FeII_Oxy_3 PF13640.6 GAX20703.1 - 4.1e-12 46.8 0.0 8.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX20703.1 - 3.1e-05 24.4 0.0 8e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF4255 PF14065.6 GAX20703.1 - 0.0032 17.1 0.3 0.0055 16.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4255) DUF3328 PF11807.8 GAX20703.1 - 2.9 7.6 5.4 1.4 8.6 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) SNF2_N PF00176.23 GAX20704.1 - 1.4e-57 195.0 2.7 3.1e-39 134.7 1.3 2.6 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX20704.1 - 5.8e-20 71.7 0.1 3.3e-19 69.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 GAX20704.1 - 2e-08 34.4 10.3 2e-08 34.4 10.3 3.1 1 1 1 2 2 2 1 HSA F-box-like PF12937.7 GAX20704.1 - 0.00088 19.1 0.4 0.00088 19.1 0.4 2.5 3 0 0 3 3 3 1 F-box-like WW PF00397.26 GAX20704.1 - 0.0055 16.8 0.6 0.016 15.3 0.6 1.8 1 0 0 1 1 1 1 WW domain F-box_5 PF18511.1 GAX20704.1 - 0.0087 15.6 0.0 0.029 13.9 0.0 1.9 1 0 0 1 1 1 1 F-box F-box PF00646.33 GAX20704.1 - 0.1 12.5 0.1 0.34 10.8 0.1 1.9 1 0 0 1 1 1 0 F-box domain CCDC74_C PF14917.6 GAX20705.1 - 0.00052 20.5 0.9 0.00095 19.7 0.1 1.8 2 0 0 2 2 2 1 Coiled coil protein 74, C terminal Helo_like_N PF17111.5 GAX20705.1 - 0.017 14.5 1.8 0.019 14.3 0.4 1.7 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins KMP11 PF03037.16 GAX20705.1 - 0.043 14.6 0.2 0.079 13.8 0.2 1.4 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF5320 PF17253.2 GAX20705.1 - 0.33 12.1 1.5 5.3 8.2 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Mus7 PF09462.10 GAX20706.1 - 1.7 7.4 5.7 0.47 9.3 2.1 1.7 2 0 0 2 2 2 0 Mus7/MMS22 family FA_hydroxylase PF04116.13 GAX20707.1 - 2.5e-13 50.5 9.2 2.5e-13 50.5 9.2 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NAD_binding_10 PF13460.6 GAX20708.1 - 1.1e-16 61.3 0.0 1.3e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX20708.1 - 0.0011 18.0 0.2 0.0016 17.5 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GAX20708.1 - 0.0039 16.8 0.0 0.0071 15.9 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 GAX20708.1 - 0.0051 17.2 0.1 0.014 15.8 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAX20708.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAX20708.1 - 0.097 12.8 0.1 0.58 10.3 0.1 2.2 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus SHS2_Rpb7-N PF03876.17 GAX20709.1 - 4.3e-11 43.0 0.1 1.2e-10 41.5 0.2 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 GAX20709.1 - 2.6e-07 30.9 0.0 5.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 GAX20709.1 - 0.0055 16.9 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 FKBP_C PF00254.28 GAX20710.1 - 1e-28 99.4 0.0 1.9e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 GAX20710.1 - 6.4e-05 23.8 0.0 0.00012 23.0 0.0 1.4 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FTCD_N PF07837.12 GAX20712.1 - 2.6e-15 56.7 0.9 9.3e-15 54.8 0.9 1.8 1 1 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain Phasin_2 PF09361.10 GAX20712.1 - 0.0029 17.9 2.6 0.0048 17.1 0.7 2.1 2 0 0 2 2 2 1 Phasin protein DUF842 PF05811.13 GAX20712.1 - 0.033 13.9 0.1 0.065 12.9 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) 2-Hacid_dh_C PF02826.19 GAX20713.1 - 3.2e-49 166.7 0.0 5.7e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX20713.1 - 4.4e-23 81.4 0.0 9.3e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAX20713.1 - 7.6e-06 26.2 0.0 6.6e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase cNMP_binding PF00027.29 GAX20713.1 - 0.019 15.0 0.1 0.74 9.9 0.1 2.8 2 1 0 2 2 2 0 Cyclic nucleotide-binding domain UDPG_MGDP_dh_N PF03721.14 GAX20713.1 - 0.17 11.4 1.1 0.31 10.6 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Patched PF02460.18 GAX20714.1 - 6.2e-87 292.5 10.3 7.3e-87 292.3 10.3 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 GAX20714.1 - 4.3e-34 117.6 16.6 5.8e-33 113.9 9.0 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 GAX20714.1 - 0.00075 17.3 17.1 0.0083 13.8 9.7 2.3 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family HPIH PF13323.6 GAX20714.1 - 0.032 14.1 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain with HPIH motif MMPL PF03176.15 GAX20714.1 - 0.14 11.1 26.0 0.023 13.6 10.6 2.9 3 0 0 3 3 3 0 MMPL family zf-CCHC PF00098.23 GAX20715.1 - 4.5e-07 29.6 13.4 4.5e-05 23.3 2.8 2.7 2 0 0 2 2 2 2 Zinc knuckle Methyltransf_32 PF13679.6 GAX20715.1 - 0.00026 21.0 0.3 0.005 16.8 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain zf-CCHC_6 PF15288.6 GAX20715.1 - 0.001 18.8 6.0 0.081 12.8 0.7 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 GAX20715.1 - 0.016 14.9 5.2 1.2 8.9 1.3 2.5 2 0 0 2 2 2 0 Zinc knuckle Methyltransf_28 PF02636.17 GAX20715.1 - 0.21 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase zf-C2H2_10 PF16588.5 GAX20715.1 - 2.7 7.8 8.7 0.4 10.5 0.7 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger 2-Hacid_dh_C PF02826.19 GAX20717.1 - 5.4e-49 166.0 0.2 1.3e-48 164.8 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX20717.1 - 9.4e-24 83.6 0.1 1.7e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAX20717.1 - 3.1e-06 27.4 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase cNMP_binding PF00027.29 GAX20717.1 - 0.0046 17.0 0.1 0.093 12.8 0.1 2.6 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain UDPG_MGDP_dh_N PF03721.14 GAX20717.1 - 0.008 15.8 0.9 0.018 14.6 0.2 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.21 GAX20717.1 - 0.075 13.1 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 GAX20717.1 - 0.097 12.2 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UbiA PF01040.18 GAX20718.1 - 5.5e-24 84.8 5.0 8.2e-24 84.3 5.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 GAX20719.1 - 9.5e-18 64.4 5.3 1.1e-17 64.2 5.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Tetraspanin PF00335.20 GAX20720.1 - 0.057 13.1 2.4 0.1 12.3 0.1 2.3 2 1 0 2 2 2 0 Tetraspanin family Abhydrolase_1 PF00561.20 GAX20722.1 - 5e-07 29.6 0.0 1.8e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PrmA PF06325.13 GAX20724.1 - 1e-51 176.1 0.0 5.8e-37 127.7 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX20724.1 - 5.4e-05 22.8 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX20724.1 - 0.00021 21.1 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX20724.1 - 0.0034 17.1 0.1 0.0084 15.9 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 GAX20724.1 - 0.027 15.2 0.0 0.067 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3246 PF11596.8 GAX20725.1 - 0.0061 16.0 12.3 0.0097 15.4 12.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) YL1 PF05764.13 GAX20725.1 - 0.16 12.1 1.5 0.22 11.6 1.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.6 GAX20725.1 - 0.61 10.5 16.3 0.12 12.8 12.7 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 GAX20725.1 - 0.93 7.5 3.6 1.2 7.1 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 GAX20725.1 - 1.9 8.2 3.6 3.3 7.4 3.6 1.4 1 0 0 1 1 1 0 FAM176 family Mpv17_PMP22 PF04117.12 GAX20726.1 - 3e-05 24.2 0.3 7.3e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family PseudoU_synth_2 PF00849.22 GAX20730.1 - 3e-15 56.7 0.1 8.3e-15 55.2 0.1 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 GAX20730.1 - 0.0019 17.9 0.1 0.0039 16.9 0.1 1.6 1 0 0 1 1 1 1 S4 domain SPESP1 PF15754.5 GAX20730.1 - 0.024 13.8 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 PqiA PF04403.13 GAX20731.1 - 1.2e-09 38.1 24.6 7.9e-08 32.3 5.0 3.6 4 0 0 4 4 4 2 Paraquat-inducible protein A TMEM154 PF15102.6 GAX20731.1 - 5.8 6.8 7.6 2 8.3 0.2 3.2 2 1 1 3 3 3 0 TMEM154 protein family Chitin_synth_2 PF03142.15 GAX20732.1 - 7.2e-164 546.3 3.7 1e-163 545.7 3.7 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAX20732.1 - 1.5e-12 47.9 0.1 2.7e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAX20732.1 - 3.3e-11 43.5 6.0 8.8e-11 42.1 6.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAX20732.1 - 7.7e-08 32.3 0.0 0.00075 19.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX20732.1 - 3.9e-05 23.2 0.0 0.08 12.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 Cyt-b5 PF00173.28 GAX20732.1 - 0.00047 20.2 0.1 0.36 11.0 0.0 3.1 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain HAUS2 PF15003.6 GAX20732.1 - 0.066 12.9 5.6 0.06 13.1 3.8 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 Rhodanese PF00581.20 GAX20736.1 - 7.4e-07 29.7 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Med3 PF11593.8 GAX20736.1 - 0.17 11.1 0.4 0.2 10.8 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_72 PF03198.14 GAX20737.1 - 7.7e-50 169.9 0.0 1.1e-49 169.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 GAX20737.1 - 0.016 14.6 0.0 0.13 11.7 0.0 2.3 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Zn_ribbon_17 PF17120.5 GAX20739.1 - 5.3e-12 45.2 9.8 5.3e-12 45.2 9.8 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 GAX20739.1 - 0.00055 20.1 8.5 0.0016 18.7 8.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family DZR PF12773.7 GAX20739.1 - 0.47 10.5 11.5 1 9.4 11.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 GAX20739.1 - 2 7.9 6.3 0.24 10.9 1.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_S28 PF05577.12 GAX20740.1 - 8.3e-58 196.2 0.0 1e-57 195.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 GAX20740.1 - 0.02 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PrsW-protease PF13367.6 GAX20742.1 - 4.6e-08 32.7 9.4 2.5e-07 30.3 8.4 2.4 1 1 2 3 3 3 1 PrsW family intramembrane metalloprotease RseC_MucC PF04246.12 GAX20742.1 - 0.25 11.3 0.1 0.25 11.3 0.1 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC YrvL PF14184.6 GAX20742.1 - 9.7 6.3 16.5 0.15 12.1 0.4 3.3 3 1 0 3 3 3 0 Regulatory protein YrvL RibD_C PF01872.17 GAX20743.1 - 2.5e-25 89.5 0.1 3.6e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Asp PF00026.23 GAX20744.1 - 7e-35 121.0 0.0 1.3e-34 120.1 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAX20744.1 - 6.1e-06 26.6 0.5 0.0008 19.7 0.8 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Mad3_BUB1_I PF08311.12 GAX20745.1 - 3.3e-29 101.4 2.0 7.8e-29 100.2 2.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 GAX20745.1 - 4.9e-08 32.7 0.0 3.7e-07 29.8 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Cyclin_N2 PF16500.5 GAX20745.1 - 0.067 13.9 3.5 7.7 7.3 0.1 3.6 2 1 1 3 3 3 0 N-terminal region of cyclin_N DnaJ_C PF01556.18 GAX20746.1 - 2e-28 99.3 0.0 3.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX20746.1 - 8e-17 61.1 0.5 1.9e-16 59.9 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3818 PF12825.7 GAX20746.1 - 0.078 12.0 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Tuberin PF03542.16 GAX20746.1 - 0.17 10.9 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Tuberin SR-25 PF10500.9 GAX20746.1 - 0.25 10.9 10.4 0.44 10.1 10.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GET2 PF08690.10 GAX20746.1 - 1.8 8.1 5.2 2.9 7.5 5.2 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 LRR_8 PF13855.6 GAX20747.1 - 3.9e-20 71.4 7.7 6.4e-08 32.3 0.4 4.2 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GAX20747.1 - 9.3e-15 54.5 14.9 0.00043 20.6 0.3 6.1 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX20747.1 - 8.7e-08 31.7 6.7 3.2 8.6 0.0 6.8 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.6 GAX20747.1 - 1.7e-05 24.5 2.5 1.7 8.9 0.1 4.8 4 0 0 4 4 4 3 Leucine Rich repeat Mito_carr PF00153.27 GAX20749.1 - 4.2e-27 93.9 2.1 3.4e-11 42.9 0.0 4.4 3 2 1 4 4 4 4 Mitochondrial carrier protein PAP2 PF01569.21 GAX20749.1 - 0.68 9.7 3.7 2.6 7.8 0.5 2.6 1 1 1 2 2 2 0 PAP2 superfamily Sas10_Utp3 PF04000.15 GAX20750.1 - 1.9e-09 38.0 0.9 4.7e-09 36.7 0.2 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family TPR_1 PF00515.28 GAX20751.1 - 1e-21 75.8 7.8 2.1e-05 24.1 0.5 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX20751.1 - 1.4e-13 49.8 8.8 7.6e-06 25.7 0.4 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX20751.1 - 8.4e-12 44.6 1.1 2e-08 33.8 0.0 4.9 5 1 1 6 6 6 1 TPR repeat TPR_14 PF13428.6 GAX20751.1 - 9.8e-08 32.2 0.1 0.19 12.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX20751.1 - 2.7e-06 27.3 6.2 0.027 14.8 0.0 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX20751.1 - 1e-05 25.7 3.4 0.27 11.6 0.1 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20751.1 - 1e-05 25.3 12.8 0.14 12.5 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX20751.1 - 1.2e-05 25.7 0.5 1.2 9.7 0.1 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX20751.1 - 2.3e-05 24.9 0.4 0.0022 18.6 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX20751.1 - 0.00014 21.6 2.9 0.034 14.2 0.0 4.7 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX20751.1 - 0.0034 17.5 0.0 0.055 13.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX20751.1 - 0.01 16.4 2.8 5.1 8.0 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAX20751.1 - 0.014 15.4 2.7 5.5 7.0 0.0 3.9 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) FAT PF02259.23 GAX20751.1 - 0.017 14.4 1.8 0.024 13.9 0.3 1.9 1 1 1 2 2 2 0 FAT domain DUF1507 PF07408.11 GAX20751.1 - 0.041 13.8 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1507) Bap31_Bap29_C PF18035.1 GAX20751.1 - 0.075 13.1 0.6 0.28 11.2 0.6 2.0 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain PA28_beta PF02252.18 GAX20751.1 - 0.12 12.1 1.8 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Proteasome activator pa28 beta subunit YtxH PF12732.7 GAX20751.1 - 0.84 10.2 3.3 2.2 8.8 0.2 2.8 3 0 0 3 3 2 0 YtxH-like protein Alkyl_sulf_dimr PF14863.6 GAX20751.1 - 2.9 8.4 7.6 5.2 7.5 0.1 3.5 2 1 2 4 4 4 0 Alkyl sulfatase dimerisation MIT PF04212.18 GAX20752.1 - 0.00021 21.3 1.7 0.011 15.8 0.1 2.7 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 GAX20752.1 - 0.044 13.5 0.2 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 THUMP PF02926.17 GAX20752.1 - 0.068 13.3 0.1 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 THUMP domain Guanylate_cyc PF00211.20 GAX20753.1 - 1.1e-52 178.3 0.0 2.1e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 GAX20753.1 - 1.9e-21 76.6 0.4 3.8e-11 42.8 0.5 2.4 1 1 1 2 2 2 2 Heme NO binding associated Suv3_N PF18114.1 GAX20753.1 - 0.16 12.1 0.1 1.1 9.4 0.0 2.4 2 1 1 3 3 3 0 Suv3 helical N-terminal domain SurA_N_3 PF13624.6 GAX20753.1 - 0.23 11.2 0.7 0.61 9.9 0.1 1.9 2 0 0 2 2 2 0 SurA N-terminal domain Kelch_3 PF13415.6 GAX20754.1 - 2.3e-17 62.8 12.6 0.0023 18.2 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX20754.1 - 3.6e-17 62.0 3.1 0.0013 18.9 0.0 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 GAX20754.1 - 3.5e-14 52.1 2.3 0.011 15.3 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAX20754.1 - 6.2e-12 45.3 8.3 0.0098 15.9 0.3 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAX20754.1 - 0.00069 19.6 4.1 0.36 10.9 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAX20754.1 - 0.11 12.5 4.9 8.1 6.6 0.3 4.2 5 0 0 5 5 5 0 Kelch motif Cupin_8 PF13621.6 GAX20755.1 - 1.5e-57 195.2 4.0 4.1e-57 193.8 4.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Hjc PF01870.18 GAX20755.1 - 0.00062 19.7 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 2 Archaeal holliday junction resolvase (hjc) Transport_MerF PF11431.8 GAX20756.1 - 0.057 13.3 0.8 0.18 11.7 0.4 2.0 2 0 0 2 2 2 0 Membrane transport protein MerF Fer2 PF00111.27 GAX20758.1 - 6.6e-06 26.0 0.2 1.5e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1652 PF07865.11 GAX20758.1 - 0.14 12.0 0.0 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) Na_Ca_ex PF01699.24 GAX20759.1 - 3.1e-24 85.7 30.9 1.4e-14 54.3 19.8 3.2 2 1 1 3 3 3 3 Sodium/calcium exchanger protein Peptidase_S49 PF01343.18 GAX20760.1 - 2.3e-38 131.6 1.2 5.9e-38 130.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 Peptidase_S49_N PF08496.10 GAX20760.1 - 5.6e-21 75.2 1.4 3.9e-19 69.2 0.1 3.4 3 1 0 3 3 3 1 Peptidase family S49 N-terminal SDH_sah PF01972.16 GAX20760.1 - 0.0054 15.8 0.1 0.01 14.9 0.1 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase T3SchapCesA PF11439.8 GAX20760.1 - 0.094 12.9 0.1 4.3 7.5 0.1 2.7 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA Pkinase_Tyr PF07714.17 GAX20761.1 - 1e-20 74.1 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX20761.1 - 3.1e-16 59.5 0.0 6.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain FAD_binding_3 PF01494.19 GAX20762.1 - 7.6e-21 74.7 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAX20762.1 - 2.1e-06 27.8 0.1 5.3e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX20762.1 - 4.9e-06 26.0 0.1 0.0001 21.7 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX20762.1 - 6.8e-06 25.9 0.7 0.027 14.1 0.6 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX20762.1 - 0.00015 20.7 0.0 0.00065 18.5 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAX20762.1 - 0.0002 20.6 0.1 0.018 14.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAX20762.1 - 0.0016 17.5 0.3 0.0038 16.3 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 GAX20762.1 - 0.0023 17.3 0.0 0.55 9.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAX20762.1 - 0.013 14.7 0.0 0.09 12.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAX20762.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 GAX20762.1 - 0.03 14.3 0.5 0.13 12.2 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAX20762.1 - 0.032 14.8 0.0 0.28 11.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAX20762.1 - 0.074 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 GAX20762.1 - 0.091 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 GAX20762.1 - 0.18 10.6 0.1 14 4.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase SMK-1 PF04802.15 GAX20763.1 - 3.1e-41 141.3 0.0 2.8e-40 138.2 0.0 2.3 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 CDC45 PF02724.14 GAX20764.1 - 0.51 8.6 4.1 0.49 8.6 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein UQ_con PF00179.26 GAX20765.1 - 4.2e-38 130.2 0.0 4.7e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX20765.1 - 0.0045 17.3 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain Acyl-thio_N PF12590.8 GAX20766.1 - 0.13 12.8 5.2 0.18 12.3 0.1 2.7 3 0 0 3 3 3 0 Acyl-ATP thioesterase Acyl_transf_3 PF01757.22 GAX20768.1 - 8.1e-20 71.2 39.5 8.1e-20 71.2 39.5 1.7 2 0 0 2 2 2 1 Acyltransferase family Nop52 PF05997.12 GAX20769.1 - 0.03 14.1 5.3 0.5 10.1 0.6 2.4 1 1 1 2 2 2 0 Nucleolar protein,Nop52 End3 PF12761.7 GAX20769.1 - 0.19 11.9 10.9 0.31 11.2 10.9 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3287 PF11690.8 GAX20769.1 - 0.23 11.2 5.2 5.8 6.7 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Fib_alpha PF08702.10 GAX20769.1 - 0.24 11.6 10.3 0.13 12.4 7.7 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 GAX20769.1 - 0.43 10.9 15.9 7.2 6.9 10.3 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain PEP-utilisers_N PF05524.13 GAX20769.1 - 0.74 10.0 7.8 8.3 6.6 7.8 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal YabA PF06156.13 GAX20769.1 - 1.3 9.7 10.1 0.31 11.7 3.4 2.8 1 1 2 3 3 3 0 Initiation control protein YabA DUF5320 PF17253.2 GAX20769.1 - 1.3 10.1 6.0 6.3 7.9 0.3 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5320) LMBR1 PF04791.16 GAX20769.1 - 3.5 6.4 5.5 3.6 6.4 5.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 GAX20769.1 - 6.1 6.1 9.6 10 5.3 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 GAX20770.1 - 1.4e-79 267.2 0.0 2.1e-79 266.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX20770.1 - 1.7e-37 129.2 0.2 2.6e-37 128.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 GAX20770.1 - 0.0002 20.8 0.2 0.00056 19.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX20770.1 - 0.00057 18.8 0.0 0.00097 18.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF2135 PF09906.9 GAX20770.1 - 0.12 12.6 0.1 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) APH PF01636.23 GAX20770.1 - 0.17 11.8 0.0 1.2 9.0 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Hydrolase_4 PF12146.8 GAX20771.1 - 1.1e-07 31.4 0.0 3.8e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX20771.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PseudoU_synth_2 PF00849.22 GAX20772.1 - 2.1e-23 83.2 0.2 5.6e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 RNA pseudouridylate synthase UPF0176_N PF17773.1 GAX20772.1 - 7.2e-16 58.3 0.0 2.4e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAX20772.1 - 6.1e-12 45.7 11.6 6.1e-12 45.7 11.6 3.2 3 0 0 3 3 3 1 Rhodanase C-terminal Rhodanese PF00581.20 GAX20772.1 - 8.4e-08 32.7 0.1 2.3e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DUF932 PF06067.11 GAX20772.1 - 0.02 14.7 1.9 0.027 14.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF932) FAD_SOX PF18371.1 GAX20772.1 - 0.079 13.3 0.2 14 6.1 0.1 3.0 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase UBX PF00789.20 GAX20773.1 - 4.4e-10 39.6 0.0 9.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF4746 PF15928.5 GAX20773.1 - 0.23 10.8 3.4 1.4 8.2 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CENP-L PF13092.6 GAX20773.1 - 2.9 8.1 9.6 0.27 11.4 0.2 2.9 1 1 1 3 3 3 0 Kinetochore complex Sim4 subunit Fta1 CPBP PF02517.16 GAX20775.1 - 4.7e-13 49.3 11.6 4.7e-13 49.3 11.6 3.3 2 1 1 3 3 3 2 CPBP intramembrane metalloprotease Bee_toxin PF17454.2 GAX20775.1 - 0.1 12.6 0.5 0.22 11.6 0.5 1.5 1 0 0 1 1 1 0 Honey bee toxin adh_short PF00106.25 GAX20777.1 - 7.6e-36 123.4 0.1 4.3e-30 104.6 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX20777.1 - 1.5e-22 80.3 0.0 1e-17 64.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX20777.1 - 2.5e-10 40.6 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX20777.1 - 0.00091 18.7 0.2 0.0016 18.0 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX20777.1 - 0.063 13.2 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Sterol_MT_C PF08498.10 GAX20778.1 - 3.7e-21 75.2 0.1 6.8e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAX20778.1 - 3.3e-16 59.7 0.0 5.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20778.1 - 4.2e-14 53.0 0.0 7.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX20778.1 - 9.2e-12 45.0 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX20778.1 - 1.5e-10 41.2 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX20778.1 - 3.2e-09 36.5 0.0 4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 GAX20778.1 - 4.3e-07 30.6 0.0 1.2e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX20778.1 - 2.5e-06 27.0 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 GAX20778.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 GAX20778.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 GAX20779.1 - 9.5e-41 137.6 5.1 1.6e-13 50.4 0.1 4.2 3 2 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.21 GAX20781.1 - 4.9e-10 39.1 0.3 7e-08 32.0 0.3 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family ubiquitin PF00240.23 GAX20783.1 - 1.7e-09 37.3 0.0 3.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 GAX20783.1 - 4.5e-07 29.6 0.2 2.1e-06 27.5 0.2 2.3 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 GAX20783.1 - 5.5e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 GAX20783.1 - 0.0011 18.6 52.6 0.0056 16.4 13.2 4.8 2 2 1 3 3 3 3 XPC-binding domain Rad60-SLD PF11976.8 GAX20783.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAX20783.1 - 0.04 14.5 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CUE PF02845.16 GAX20783.1 - 0.11 12.2 1.4 0.34 10.7 0.0 2.4 2 0 0 2 2 2 0 CUE domain GlnE PF03710.15 GAX20783.1 - 0.15 11.5 7.5 0.56 9.6 1.4 2.4 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase Condensin2nSMC PF12422.8 GAX20783.1 - 0.37 11.0 1.6 0.86 9.8 1.6 1.5 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Bep_C_terminal PF17841.1 GAX20783.1 - 7.9 6.8 8.6 8.9 6.6 0.3 3.5 2 1 0 3 3 3 0 BID domain of Bartonella effector protein (Bep) zf-CXXC PF02008.20 GAX20784.1 - 0.0013 18.7 119.5 0.11 12.5 16.9 6.6 6 0 0 6 6 6 4 CXXC zinc finger domain TUDOR_5 PF18359.1 GAX20784.1 - 0.0014 18.3 0.1 0.0052 16.5 0.0 2.1 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 53-BP1_Tudor PF09038.10 GAX20784.1 - 0.0057 16.6 0.1 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 Tumour suppressor p53-binding protein-1 Tudor Tudor_3 PF18115.1 GAX20784.1 - 0.05 13.4 0.3 0.87 9.5 0.0 2.6 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain RXT2_N PF08595.11 GAX20784.1 - 0.057 13.5 3.8 0.55 10.2 4.0 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4537 PF15057.6 GAX20784.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF4484 PF14831.6 GAX20784.1 - 0.17 11.9 4.4 0.33 10.9 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Nop14 PF04147.12 GAX20784.1 - 0.42 8.8 13.2 0.67 8.1 13.2 1.2 1 0 0 1 1 1 0 Nop14-like family VIR_N PF15912.5 GAX20784.1 - 0.65 9.6 4.6 1.1 8.8 4.6 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal FAM176 PF14851.6 GAX20784.1 - 0.66 9.6 9.5 1.5 8.4 9.5 1.5 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 GAX20784.1 - 0.69 7.9 7.5 1.2 7.1 7.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_60s PF00428.19 GAX20784.1 - 1.6 9.4 9.9 5.1 7.7 9.9 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4746 PF15928.5 GAX20784.1 - 1.6 8.0 7.4 3.1 7.1 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP1_TM PF14812.6 GAX20784.1 - 1.8 9.0 8.8 7 7.1 8.8 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CPSF100_C PF13299.6 GAX20784.1 - 4.1 7.5 6.4 5.6 7.1 4.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 GAX20784.1 - 5.4 6.1 6.6 9.1 5.4 6.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-CXXC PF02008.20 GAX20785.1 - 1.9e-05 24.6 52.3 0.043 13.9 6.0 3.7 3 0 0 3 3 3 3 CXXC zinc finger domain DUF4537 PF15057.6 GAX20786.1 - 0.00087 19.3 0.0 0.035 14.1 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 GAX20786.1 - 0.0085 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 GAX20786.1 - 0.019 14.8 0.1 0.047 13.5 0.1 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 GAX20786.1 - 0.026 14.2 0.1 0.064 13.0 0.1 1.7 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 zf-CXXC PF02008.20 GAX20786.1 - 8.7 6.5 109.0 0.059 13.4 11.7 5.5 5 0 0 5 5 5 0 CXXC zinc finger domain Thioredoxin_8 PF13905.6 GAX20787.1 - 1e-20 73.9 0.0 1.9e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GAX20787.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 GAX20787.1 - 0.14 12.6 2.2 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain DUF5623 PF18536.1 GAX20787.1 - 0.27 11.5 4.3 0.47 10.7 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) FG-GAP_2 PF14312.6 GAX20788.1 - 4e-10 39.8 12.1 0.011 16.0 0.0 5.2 5 0 0 5 5 5 3 FG-GAP repeat FG-GAP_2 PF14312.6 GAX20789.1 - 2.2e-10 40.6 18.0 0.012 15.8 0.2 5.6 5 0 0 5 5 5 4 FG-GAP repeat Sporozoite_P67 PF05642.11 GAX20789.1 - 5.8 4.9 11.5 9.1 4.2 11.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-RING_2 PF13639.6 GAX20790.1 - 2.1e-11 44.0 11.2 5.8e-11 42.6 11.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX20790.1 - 2e-07 30.6 8.5 5.9e-07 29.1 8.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX20790.1 - 4.7e-06 26.3 11.0 1.3e-05 25.0 11.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX20790.1 - 0.00024 21.3 12.0 0.00092 19.5 12.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain SAP PF02037.27 GAX20790.1 - 0.0018 17.9 5.3 1.1 9.1 0.2 3.9 4 0 0 4 4 4 2 SAP domain Armet PF10208.9 GAX20790.1 - 0.0021 18.0 0.1 14 5.6 0.0 3.9 4 0 0 4 4 4 0 Degradation arginine-rich protein for mis-folding zf-C3HC4 PF00097.25 GAX20790.1 - 0.0021 17.9 10.2 0.0058 16.5 10.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX20790.1 - 0.0045 16.6 9.8 0.0094 15.6 9.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 GAX20790.1 - 0.013 15.4 11.6 0.029 14.2 11.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX20790.1 - 0.013 15.5 3.8 0.028 14.5 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf_C2H2_10 PF18414.1 GAX20790.1 - 0.063 12.8 4.0 1.3 8.6 0.8 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-RING_UBOX PF13445.6 GAX20790.1 - 0.068 13.2 10.3 0.58 10.2 10.2 2.5 1 1 1 2 2 2 0 RING-type zinc-finger Rho_N PF07498.12 GAX20790.1 - 0.076 13.0 2.4 1.9 8.5 0.0 3.2 4 0 0 4 4 4 0 Rho termination factor, N-terminal domain Prok-RING_4 PF14447.6 GAX20790.1 - 0.1 12.4 9.3 0.29 11.0 9.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.11 GAX20790.1 - 0.15 12.1 0.3 0.31 11.0 0.3 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_5 PF14634.6 GAX20790.1 - 0.25 11.3 11.5 0.64 10.0 11.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain GDPD PF03009.17 GAX20791.1 - 1.2e-23 84.2 0.0 5.4e-22 78.8 0.0 2.5 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family DUF957 PF06117.11 GAX20791.1 - 0.11 12.1 0.0 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) HNH_3 PF13392.6 GAX20792.1 - 2e-08 33.8 1.7 1.1e-06 28.3 0.3 2.5 2 0 0 2 2 2 2 HNH endonuclease AP2 PF00847.20 GAX20792.1 - 0.015 15.5 0.0 0.058 13.6 0.0 2.0 1 0 0 1 1 1 0 AP2 domain TFIIA PF03153.13 GAX20792.1 - 7.1 6.5 26.3 0.89 9.5 22.4 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3684 PF12449.8 GAX20795.1 - 5.8e-110 368.8 12.4 5.4e-78 262.9 2.0 4.9 2 2 2 4 4 4 4 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 GAX20795.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HNH_3 PF13392.6 GAX20799.1 - 9e-13 47.8 2.9 8.4e-07 28.7 0.3 2.4 2 0 0 2 2 2 2 HNH endonuclease Lipase_3 PF01764.25 GAX20800.1 - 1.5e-17 63.8 0.0 7.9e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAX20800.1 - 0.003 18.2 0.6 0.007 17.0 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FlgD PF03963.14 GAX20800.1 - 0.11 12.9 0.3 0.27 11.6 0.3 1.6 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region AAA_23 PF13476.6 GAX20801.1 - 2.6e-21 77.1 2.9 2.6e-21 77.1 2.9 6.3 3 2 1 4 4 1 1 AAA domain SMC_N PF02463.19 GAX20801.1 - 1.1e-16 60.9 49.0 7e-16 58.3 49.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX20801.1 - 1.5e-11 44.7 15.6 1.5e-11 44.7 15.6 3.6 2 1 1 3 3 1 1 AAA ATPase domain AAA_29 PF13555.6 GAX20801.1 - 8.1e-05 22.3 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GAX20801.1 - 0.00011 22.1 8.8 0.00067 19.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF948 PF06103.11 GAX20801.1 - 0.0072 16.6 0.2 0.0072 16.6 0.2 7.2 5 2 3 8 8 8 3 Bacterial protein of unknown function (DUF948) HrpB7 PF09486.10 GAX20801.1 - 0.0081 16.6 12.8 0.0081 16.6 12.8 5.8 3 2 2 5 5 5 2 Bacterial type III secretion protein (HrpB7) DivIC PF04977.15 GAX20801.1 - 0.0095 15.7 3.0 0.0095 15.7 3.0 10.0 6 4 6 12 12 12 1 Septum formation initiator SbcCD_C PF13558.6 GAX20801.1 - 0.025 14.8 0.2 0.13 12.5 0.0 2.3 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Nup54 PF13874.6 GAX20801.1 - 0.043 13.9 0.3 0.043 13.9 0.3 5.9 5 1 1 6 6 5 0 Nucleoporin complex subunit 54 Mce4_CUP1 PF11887.8 GAX20801.1 - 0.56 9.6 2.8 10 5.5 0.1 2.9 2 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative ABC_tran PF00005.27 GAX20801.1 - 0.93 10.0 0.0 0.93 10.0 0.0 5.8 3 2 0 3 3 1 0 ABC transporter DUF3584 PF12128.8 GAX20801.1 - 2.1 5.7 91.7 1.9 5.9 34.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Lip_prot_lig_C PF10437.9 GAX20801.1 - 4.2 7.4 6.1 3.1 7.9 0.9 3.6 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Laminin_II PF06009.12 GAX20801.1 - 8.8 6.4 68.7 0.032 14.2 2.1 7.2 4 2 4 8 8 8 0 Laminin Domain II Pkinase PF00069.25 GAX20802.1 - 3.7e-136 452.7 0.0 6.9e-70 235.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX20802.1 - 5e-59 199.7 0.0 4.7e-29 101.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX20802.1 - 1.8e-14 53.3 0.1 3.5e-06 26.1 0.0 3.3 4 0 0 4 4 4 2 Fungal protein kinase Kdo PF06293.14 GAX20802.1 - 3.4e-10 39.6 0.2 0.00071 19.0 0.1 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX20802.1 - 2e-09 37.8 0.6 0.14 12.0 0.0 4.6 3 2 2 5 5 5 4 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX20802.1 - 2.5e-07 30.3 0.0 0.002 17.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Imm7 PF15585.6 GAX20802.1 - 0.018 15.3 0.0 4.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 7 FTA2 PF13095.6 GAX20802.1 - 0.045 13.4 0.7 17 5.0 0.0 3.2 3 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 NOA36 PF06524.12 GAX20803.1 - 1.4 8.1 6.8 3.1 7.0 6.8 1.5 1 0 0 1 1 1 0 NOA36 protein CtaG_Cox11 PF04442.14 GAX20804.1 - 4.1e-56 189.2 0.1 5.2e-55 185.6 0.1 2.2 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 OSCP PF00213.18 GAX20806.1 - 2e-42 145.2 0.7 2.4e-42 145.0 0.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Pam16 PF03656.13 GAX20808.1 - 1.2e-20 73.8 2.9 1.7e-20 73.3 2.9 1.2 1 0 0 1 1 1 1 Pam16 Phage_holin_Dp1 PF16938.5 GAX20808.1 - 0.018 15.2 0.3 0.028 14.6 0.3 1.3 1 0 0 1 1 1 0 Putative phage holin Dp-1 IncD PF17628.2 GAX20808.1 - 0.026 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D RNA_polI_A14 PF08203.11 GAX20808.1 - 0.28 11.9 5.3 4.2 8.2 0.3 2.5 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Pkinase PF00069.25 GAX20809.1 - 3.3e-74 249.6 0.0 4.1e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX20809.1 - 2.8e-35 121.9 0.0 3.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX20809.1 - 0.00094 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mem_trans PF03547.18 GAX20810.1 - 1.7e-10 39.9 22.0 3.3e-09 35.6 22.0 2.6 1 1 0 1 1 1 1 Membrane transport protein FH2 PF02181.23 GAX20811.1 - 1.2e-61 208.9 3.0 1.2e-61 208.9 3.0 3.1 3 1 1 4 4 4 1 Formin Homology 2 Domain CCDC53 PF10152.9 GAX20811.1 - 1.4e-09 38.5 19.2 4.8e-05 23.8 1.2 9.5 6 3 2 8 8 8 4 Subunit CCDC53 of WASH complex IL7 PF01415.16 GAX20812.1 - 0.11 12.5 0.4 9 6.3 0.1 2.2 2 0 0 2 2 2 0 Interleukin 7/9 family YL1 PF05764.13 GAX20813.1 - 1.9e-25 90.4 8.5 1.9e-25 90.4 8.5 2.0 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 GAX20813.1 - 9.7e-14 50.8 0.2 1.8e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MRP-S34 PF16053.5 GAX20813.1 - 0.14 11.8 0.7 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S34 DEAD PF00270.29 GAX20815.1 - 2.9e-47 160.7 0.0 2.6e-46 157.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX20815.1 - 3.6e-31 107.8 0.0 7.3e-29 100.4 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX20815.1 - 0.0017 18.3 0.0 0.012 15.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF3240 PF11582.8 GAX20815.1 - 0.022 14.9 0.2 0.088 13.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) HARE-HTH PF05066.13 GAX20815.1 - 0.12 12.7 0.3 0.74 10.3 0.3 2.4 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain AAA_22 PF13401.6 GAX20815.1 - 0.36 11.1 2.8 1 9.7 0.3 2.9 3 1 0 3 3 3 0 AAA domain DUF2732 PF10809.8 GAX20815.1 - 1.5 8.7 4.2 0.72 9.8 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) GCP_C_terminal PF04130.13 GAX20816.1 - 3.7e-57 194.1 5.3 6.5e-57 193.3 5.3 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAX20816.1 - 1.7e-47 162.6 0.0 3.3e-47 161.6 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal FKBP_N_2 PF18023.1 GAX20816.1 - 0.13 12.4 0.4 1 9.5 0.0 2.3 2 0 0 2 2 2 0 BDBT FKBP like N-terminal THOC7 PF05615.13 GAX20817.1 - 1.3e-05 25.4 3.5 0.1 12.9 0.3 2.7 2 0 0 2 2 2 2 Tho complex subunit 7 RasGAP_C PF03836.15 GAX20817.1 - 0.0081 16.3 0.6 0.0081 16.3 0.6 2.4 2 0 0 2 2 2 1 RasGAP C-terminus DUF1664 PF07889.12 GAX20817.1 - 0.82 9.7 8.0 3.1 7.8 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CREPT PF16566.5 GAX20817.1 - 0.96 9.6 8.1 4.7 7.4 0.4 3.2 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Viral_env_E26 PF11050.8 GAX20817.1 - 1.2 8.4 5.0 0.61 9.4 0.3 2.1 2 0 0 2 2 2 0 Virus envelope protein E26 Lzipper-MIP1 PF14389.6 GAX20817.1 - 2.3 8.6 11.9 0.053 13.8 2.7 2.9 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Spc7 PF08317.11 GAX20817.1 - 8.7 5.1 14.9 3.6 6.4 4.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DHR10 PF18595.1 GAX20817.1 - 9 6.4 16.2 0.056 13.5 4.1 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Radical_SAM PF04055.21 GAX20818.1 - 1.1e-29 104.0 0.0 2.1e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 GAX20818.1 - 7.9e-28 96.4 0.1 1.8e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 GAX20818.1 - 1.6e-09 37.6 0.1 3.6e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 TRAM domain Rotamase PF00639.21 GAX20818.1 - 4.5e-05 24.3 0.0 0.00033 21.6 0.0 2.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX20818.1 - 0.00014 22.4 0.0 0.0021 18.6 0.0 2.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain TRAM_2 PF18693.1 GAX20818.1 - 0.0061 16.7 0.3 0.21 11.8 0.1 3.0 2 1 0 2 2 2 1 TRAM domain Myb_DNA-binding PF00249.31 GAX20819.1 - 4.5e-11 42.8 0.0 7.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX20819.1 - 0.013 15.4 0.2 0.023 14.6 0.2 1.5 1 1 0 1 1 1 0 Myb DNA-binding like DASH_Dad2 PF08654.10 GAX20819.1 - 0.14 12.6 0.1 0.27 11.7 0.0 1.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 Mg-por_mtran_C PF07109.11 GAX20820.1 - 1e-35 122.0 0.2 1.1e-34 118.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 GAX20820.1 - 3.8e-14 53.2 0.1 6.8e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX20820.1 - 8.9e-12 45.1 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX20820.1 - 4.2e-09 37.0 0.0 8.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX20820.1 - 3.8e-08 33.3 0.0 6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX20820.1 - 6.7e-08 33.1 0.1 1.4e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX20820.1 - 1.2e-07 31.4 0.1 1.6e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 GAX20820.1 - 8.7e-07 28.5 0.2 2.7e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 GAX20820.1 - 1e-06 28.7 0.4 0.00011 22.2 0.1 2.7 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 GAX20820.1 - 1.4e-06 27.9 0.1 2.1e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAX20820.1 - 3.4e-05 23.9 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX20820.1 - 0.00014 21.3 0.1 0.00026 20.4 0.1 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 GAX20820.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 GAX20820.1 - 0.00027 20.6 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_PK PF05891.12 GAX20820.1 - 0.00029 20.4 0.1 0.00048 19.7 0.1 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 GAX20820.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA_U5-meth_tr PF05958.11 GAX20820.1 - 0.0092 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase GidB PF02527.15 GAX20820.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G DUF1307 PF06998.11 GAX20820.1 - 0.039 14.0 1.2 0.054 13.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1307) DOT1 PF08123.13 GAX20820.1 - 0.07 12.6 0.1 0.17 11.4 0.1 1.6 1 1 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.18 GAX20820.1 - 0.13 12.0 0.2 0.26 10.9 0.2 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Mito_carr PF00153.27 GAX20822.1 - 1.9e-60 200.8 2.6 1.5e-19 69.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 GAX20822.1 - 0.032 14.3 0.0 28 4.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) Mt_ATP-synt_B PF05405.14 GAX20823.1 - 0.0032 17.1 0.1 0.0044 16.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TssO PF17561.2 GAX20823.1 - 0.014 15.5 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO Seryl_tRNA_N PF02403.22 GAX20823.1 - 0.024 14.9 2.0 0.03 14.6 2.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 GAX20823.1 - 0.039 14.5 0.3 0.042 14.4 0.3 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region Gram_pos_anchor PF00746.21 GAX20823.1 - 0.051 13.5 0.6 0.051 13.5 0.6 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif CcmD PF04995.14 GAX20823.1 - 0.8 9.8 6.1 12 6.1 0.0 3.0 2 1 1 3 3 3 0 Heme exporter protein D (CcmD) Methyltransf_8 PF05148.15 GAX20824.1 - 8.6e-77 257.9 0.2 1.1e-76 257.5 0.2 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 GAX20824.1 - 1.9e-07 31.7 0.1 9.8e-07 29.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20824.1 - 7.5e-06 26.6 0.1 0.00064 20.4 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX20824.1 - 7.9e-05 22.5 0.1 0.012 15.4 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX20824.1 - 0.0045 16.3 0.1 0.05 12.9 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GAX20824.1 - 0.032 14.2 0.0 0.032 14.2 0.0 2.8 2 2 0 2 2 2 0 Methyltransferase domain WD40 PF00400.32 GAX20825.1 - 4e-28 97.1 9.9 9.5e-07 29.4 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX20825.1 - 8.5e-13 48.4 0.1 0.036 14.4 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 GAX20825.1 - 0.037 13.1 0.1 0.2 10.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) PQQ_2 PF13360.6 GAX20825.1 - 0.038 13.6 1.2 0.095 12.3 0.0 2.2 3 0 0 3 3 3 0 PQQ-like domain BBS2_Mid PF14783.6 GAX20825.1 - 0.065 13.3 0.0 8.2 6.5 0.0 2.9 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 GAX20825.1 - 0.067 13.2 0.8 0.45 10.5 0.3 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat Gamma-thionin PF00304.20 GAX20827.1 - 0.19 12.0 2.9 0.76 10.1 0.1 2.5 2 0 0 2 2 2 0 Gamma-thionin family Thioredoxin PF00085.20 GAX20828.1 - 1.6e-08 34.4 0.0 2.2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 GAX20828.1 - 0.064 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin zf-nanos PF05741.13 GAX20828.1 - 0.068 13.4 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 Nanos RNA binding domain Met_10 PF02475.16 GAX20829.1 - 4.6e-51 173.4 0.0 9e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 GAX20829.1 - 0.0022 17.2 0.4 0.0049 16.1 0.4 1.7 1 1 1 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase CD34_antigen PF06365.12 GAX20830.1 - 0.38 10.3 0.1 0.38 10.3 0.1 2.4 2 0 0 2 2 2 0 CD34/Podocalyxin family Mucin PF01456.17 GAX20830.1 - 2 8.4 10.5 0.11 12.5 3.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein THEG PF14912.6 GAX20831.1 - 0.024 15.1 0.0 0.092 13.2 0.0 2.0 1 0 0 1 1 1 0 Testicular haploid expressed repeat Ribosomal_L37e PF01907.19 GAX20831.1 - 0.82 9.9 3.8 17 5.6 0.0 3.7 3 0 0 3 3 3 0 Ribosomal protein L37e Fer4 PF00037.27 GAX20831.1 - 1.7 8.6 4.2 16 5.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Exo_endo_phos PF03372.23 GAX20832.1 - 0.055 13.0 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CPP1-like PF11833.8 GAX20833.1 - 0.1 12.2 0.2 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PAS_9 PF13426.7 GAX20834.1 - 1e-19 70.7 0.1 3.6e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 PAS domain bZIP_2 PF07716.15 GAX20834.1 - 5.8e-08 32.7 12.6 1.3e-07 31.6 12.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PAS_3 PF08447.12 GAX20834.1 - 1.3e-07 31.8 0.0 2.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold bZIP_1 PF00170.21 GAX20834.1 - 2.9e-07 30.5 11.6 5.7e-07 29.5 11.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.25 GAX20834.1 - 1.4e-05 25.1 0.0 3.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 GAX20834.1 - 0.00021 21.2 0.0 0.25 11.4 0.0 3.3 4 1 0 4 4 4 2 PAS domain PAS_4 PF08448.10 GAX20834.1 - 0.0011 19.2 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold HAP1_N PF04849.13 GAX20834.1 - 0.017 14.3 7.1 0.025 13.8 7.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1840 PF08895.11 GAX20834.1 - 0.11 12.9 1.7 0.28 11.5 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) Cofilin_ADF PF00241.20 GAX20835.1 - 2.4e-36 124.2 0.0 2.8e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ORMDL PF04061.14 GAX20836.1 - 1.1e-25 90.0 4.4 1.6e-25 89.5 4.4 1.2 1 0 0 1 1 1 1 ORMDL family Cyt_bd_oxida_II PF02322.15 GAX20836.1 - 0.0052 16.2 2.0 0.0075 15.7 2.0 1.2 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II UAA PF08449.11 GAX20838.1 - 2.9e-55 187.6 16.5 3.4e-55 187.4 16.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX20838.1 - 3.3e-05 24.1 23.2 0.018 15.2 4.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAX20838.1 - 0.00043 19.7 12.7 0.00079 18.9 12.7 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 GAX20838.1 - 0.00058 18.9 1.4 0.00058 18.9 1.4 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TMEM51 PF15345.6 GAX20839.1 - 0.087 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CcmD PF04995.14 GAX20839.1 - 3.7 7.7 6.1 6 7.0 6.1 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PepSY_TM PF03929.16 GAX20840.1 - 0.066 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DENN PF02141.21 GAX20841.1 - 5.1e-34 117.8 1.4 8.6e-34 117.1 1.4 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain WD40 PF00400.32 GAX20841.1 - 6.5e-13 49.0 28.3 1.8e-05 25.4 1.0 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat SBF2 PF12335.8 GAX20841.1 - 0.00068 19.3 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 Myotubularin protein uDENN PF03456.18 GAX20841.1 - 0.0019 18.9 0.0 0.0054 17.5 0.0 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 GAX20841.1 - 0.019 14.9 0.3 0.072 13.1 0.3 2.0 1 0 0 1 1 1 0 dDENN domain zf-RING_2 PF13639.6 GAX20842.1 - 9.1e-09 35.5 10.3 9.1e-09 35.5 10.3 2.1 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX20842.1 - 5.6e-06 26.1 9.9 2e-05 24.3 9.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.17 GAX20842.1 - 1.8e-05 24.3 0.6 4.7e-05 23.0 0.6 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-C3HC4 PF00097.25 GAX20842.1 - 2.9e-05 23.9 9.8 8.5e-05 22.4 9.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX20842.1 - 4e-05 23.6 9.3 4e-05 23.6 9.3 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 GAX20842.1 - 0.0022 18.1 5.1 0.011 15.9 5.1 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAX20842.1 - 0.0031 17.8 15.4 0.017 15.4 15.4 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 GAX20842.1 - 0.008 15.9 7.8 0.02 14.7 7.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 GAX20842.1 - 0.011 15.9 9.6 0.011 15.9 9.6 2.9 3 1 0 3 3 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 GAX20842.1 - 0.011 15.8 9.1 0.03 14.3 9.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.6 GAX20842.1 - 0.025 14.5 3.7 0.025 14.5 3.7 2.4 2 1 1 3 3 2 0 Prokaryotic RING finger family 1 SAP PF02037.27 GAX20842.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 SAP domain zf-C3HC4_3 PF13920.6 GAX20842.1 - 0.037 13.9 9.7 0.11 12.4 9.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAX20842.1 - 0.061 13.4 9.5 0.17 12.0 9.5 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_11 PF17123.5 GAX20842.1 - 0.092 12.5 4.3 0.24 11.2 4.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger Zf_RING PF16744.5 GAX20842.1 - 0.094 12.8 5.4 0.22 11.6 5.4 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 GAX20842.1 - 0.41 11.0 18.1 0.15 12.3 13.9 2.5 2 1 1 3 3 3 0 RING-like domain NAD_binding_4 PF07993.12 GAX20844.1 - 6e-39 133.7 0.0 1.9e-38 132.1 0.0 1.9 3 0 0 3 3 3 1 Male sterility protein Epimerase PF01370.21 GAX20844.1 - 0.0032 17.0 0.0 0.02 14.4 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF512 PF04459.12 GAX20844.1 - 0.083 12.2 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF512) DUF5446 PF17522.2 GAX20844.1 - 0.11 12.6 0.0 22 5.3 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5446) DEAD PF00270.29 GAX20845.1 - 2.1e-35 122.1 0.0 3.4e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX20845.1 - 1.3e-25 89.9 0.0 2.4e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX20845.1 - 2.1e-05 24.6 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX20845.1 - 0.0047 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 GAX20845.1 - 0.19 10.9 0.0 0.52 9.5 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase BST2 PF16716.5 GAX20846.1 - 2.4 8.8 8.4 3.6 8.3 5.7 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4407 PF14362.6 GAX20847.1 - 0.00029 20.3 16.6 0.00081 18.8 9.9 2.7 1 1 2 3 3 3 3 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 GAX20847.1 - 0.00061 20.0 20.9 1.9 8.7 8.9 3.6 1 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding AIP3 PF03915.13 GAX20847.1 - 0.0014 17.8 17.6 0.0061 15.7 17.6 1.9 1 1 0 1 1 1 1 Actin interacting protein 3 ATG16 PF08614.11 GAX20847.1 - 0.0014 18.9 24.0 0.0061 16.8 7.6 2.4 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 GAX20847.1 - 0.0015 18.4 8.8 0.0015 18.4 8.8 2.7 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 GAX20847.1 - 0.0015 18.2 15.0 0.76 9.6 0.0 4.5 3 1 1 4 4 4 2 Septum formation initiator ZapB PF06005.12 GAX20847.1 - 0.0019 18.6 17.0 1.3 9.5 0.0 4.8 4 1 0 4 4 4 1 Cell division protein ZapB Spc7 PF08317.11 GAX20847.1 - 0.0034 16.3 4.0 0.0034 16.3 4.0 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF2203 PF09969.9 GAX20847.1 - 0.0035 18.1 8.8 0.42 11.3 0.8 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 GAX20847.1 - 0.0039 17.7 20.9 0.03 14.8 8.6 3.1 1 1 2 3 3 3 1 Apg6 coiled-coil region Ribosomal_L29 PF00831.23 GAX20847.1 - 0.0061 16.5 12.5 3.8 7.5 0.0 5.7 3 1 2 5 5 5 0 Ribosomal L29 protein PRKG1_interact PF15898.5 GAX20847.1 - 0.0067 17.3 5.6 0.0067 17.3 5.6 4.1 2 1 3 5 5 4 2 cGMP-dependent protein kinase interacting domain Golgin_A5 PF09787.9 GAX20847.1 - 0.0078 15.7 18.9 0.13 11.7 3.9 3.2 1 1 2 3 3 3 2 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 GAX20847.1 - 0.012 15.6 24.5 0.61 10.2 3.1 4.1 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein FlxA PF14282.6 GAX20847.1 - 0.014 15.3 20.0 0.038 14.0 1.8 3.8 2 2 1 3 3 3 0 FlxA-like protein TMPIT PF07851.13 GAX20847.1 - 0.017 14.4 14.2 0.035 13.3 1.2 2.5 3 0 0 3 3 2 0 TMPIT-like protein Phage_GP20 PF06810.11 GAX20847.1 - 0.02 14.7 17.5 0.026 14.4 1.3 3.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 GAX20847.1 - 0.024 15.0 9.7 4.1 7.9 0.3 4.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 GAX20847.1 - 0.024 14.8 1.4 0.024 14.8 1.4 2.9 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family HR1 PF02185.16 GAX20847.1 - 0.025 14.7 13.9 5.8 7.1 1.9 4.5 3 2 0 3 3 3 0 Hr1 repeat SOGA PF11365.8 GAX20847.1 - 0.026 15.7 13.0 0.62 11.2 4.5 3.5 1 1 3 4 4 4 0 Protein SOGA EHN PF06441.12 GAX20847.1 - 0.027 14.8 3.4 0.13 12.6 0.2 3.0 1 1 1 2 2 2 0 Epoxide hydrolase N terminus TMF_DNA_bd PF12329.8 GAX20847.1 - 0.028 14.4 23.2 0.25 11.3 0.1 4.7 2 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF1640 PF07798.11 GAX20847.1 - 0.029 14.4 20.3 0.18 11.9 8.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 GAX20847.1 - 0.03 14.4 12.6 0.12 12.4 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DASH_Dad2 PF08654.10 GAX20847.1 - 0.041 14.3 0.9 0.041 14.3 0.9 3.2 3 1 0 4 4 1 0 DASH complex subunit Dad2 Occludin_ELL PF07303.13 GAX20847.1 - 0.079 13.7 0.3 0.079 13.7 0.3 4.6 2 1 3 5 5 4 0 Occludin homology domain BRE1 PF08647.11 GAX20847.1 - 0.082 13.0 19.3 0.076 13.1 3.3 3.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 GAX20847.1 - 0.087 13.1 19.3 1.2 9.4 5.2 3.5 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4618 PF15397.6 GAX20847.1 - 0.1 12.0 16.9 0.19 11.1 4.7 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) TSC22 PF01166.18 GAX20847.1 - 0.11 12.8 7.9 0.65 10.3 0.1 4.3 3 2 0 3 3 3 0 TSC-22/dip/bun family CEP63 PF17045.5 GAX20847.1 - 0.13 12.1 13.8 0.72 9.7 14.0 2.0 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF5082 PF16888.5 GAX20847.1 - 0.13 12.5 15.7 0.28 11.5 7.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Cnn_1N PF07989.11 GAX20847.1 - 0.14 12.4 14.2 1.7 8.9 1.9 4.3 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 Fez1 PF06818.15 GAX20847.1 - 0.16 12.4 20.7 2.6 8.5 4.3 2.5 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 GAX20847.1 - 0.17 11.9 20.4 0.49 10.4 3.7 3.8 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 GAX20847.1 - 0.17 12.2 13.8 1.9 8.9 0.9 3.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliJ PF02050.16 GAX20847.1 - 0.18 12.1 13.1 0.46 10.7 0.3 2.7 2 0 0 2 2 2 0 Flagellar FliJ protein Rx_N PF18052.1 GAX20847.1 - 0.19 12.0 13.2 0.028 14.7 2.9 3.4 2 2 1 3 3 3 0 Rx N-terminal domain AAA_13 PF13166.6 GAX20847.1 - 0.21 10.2 14.1 0.57 8.8 14.1 1.6 1 1 0 1 1 1 0 AAA domain SPATA1_C PF15743.5 GAX20847.1 - 0.24 11.5 24.1 1.9 8.6 17.9 3.6 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus Csm1_N PF18504.1 GAX20847.1 - 0.31 11.4 17.6 4.4 7.7 0.6 5.4 1 1 4 6 6 6 0 Csm1 N-terminal domain DUF4988 PF16378.5 GAX20847.1 - 0.36 10.5 2.9 10 5.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function LPP PF04728.13 GAX20847.1 - 0.36 11.2 11.0 11 6.5 1.0 4.4 3 2 1 4 4 3 0 Lipoprotein leucine-zipper HALZ PF02183.18 GAX20847.1 - 0.4 10.9 18.4 9 6.6 2.3 6.5 5 3 1 6 6 6 0 Homeobox associated leucine zipper DUF724 PF05266.14 GAX20847.1 - 0.49 10.2 13.5 0.18 11.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4363 PF14276.6 GAX20847.1 - 0.55 10.4 5.5 0.79 9.9 0.4 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4363) Phage_GPO PF05929.11 GAX20847.1 - 0.6 9.7 14.2 2.1 7.9 1.2 2.2 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Fzo_mitofusin PF04799.13 GAX20847.1 - 0.6 9.6 10.4 1.9 8.0 2.2 2.7 2 1 0 2 2 2 0 fzo-like conserved region FAP206 PF12018.8 GAX20847.1 - 0.65 9.5 6.9 1.9 7.9 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function Uso1_p115_C PF04871.13 GAX20847.1 - 0.69 10.3 23.8 20 5.6 1.7 3.6 1 1 1 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4482 PF14818.6 GAX20847.1 - 0.7 10.8 15.0 0.66 10.8 6.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) CHD5 PF04420.14 GAX20847.1 - 0.72 9.7 8.2 0.92 9.3 1.1 2.8 1 1 0 2 2 2 0 CHD5-like protein bZIP_1 PF00170.21 GAX20847.1 - 0.84 9.8 17.1 4.2 7.5 1.3 5.0 4 1 0 4 4 4 0 bZIP transcription factor Prefoldin_3 PF13758.6 GAX20847.1 - 0.91 9.6 7.8 2.3 8.3 0.2 3.5 1 1 2 4 4 3 0 Prefoldin subunit DUF3450 PF11932.8 GAX20847.1 - 1.1 8.5 18.6 2.3 7.5 2.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 GAX20847.1 - 1.1 9.9 19.4 19 5.9 1.6 3.8 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 GAX20847.1 - 1.3 7.5 6.1 2 6.8 5.8 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 GAX20847.1 - 1.6 9.2 7.2 2.8 8.5 2.5 3.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3972 PF13118.6 GAX20847.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3972) Pox_A_type_inc PF04508.12 GAX20847.1 - 1.9 8.5 10.7 36 4.4 0.1 6.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF4201 PF13870.6 GAX20847.1 - 1.9 8.2 15.7 1.5 8.6 1.7 3.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Uds1 PF15456.6 GAX20847.1 - 2.3 8.4 18.2 14 5.9 1.5 3.8 1 1 1 2 2 2 0 Up-regulated During Septation zf-C4H2 PF10146.9 GAX20847.1 - 2.4 8.4 15.7 61 3.8 15.6 2.5 1 1 0 1 1 1 0 Zinc finger-containing protein Cytochrom_B562 PF07361.11 GAX20847.1 - 2.7 8.7 12.8 8.8 7.1 1.0 3.6 1 1 1 3 3 3 0 Cytochrome b562 Bacillus_HBL PF05791.11 GAX20847.1 - 3 7.6 13.1 6.9 6.5 2.8 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Phasin PF05597.11 GAX20847.1 - 3.1 7.8 13.7 0.67 10.0 3.5 3.1 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YabA PF06156.13 GAX20847.1 - 3.2 8.4 13.7 11 6.7 1.8 4.0 1 1 2 3 3 3 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 GAX20847.1 - 3.2 8.1 14.7 6.5 7.1 3.4 3.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain CorA PF01544.18 GAX20847.1 - 3.4 6.9 5.3 1.8 7.8 2.5 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cep57_MT_bd PF06657.13 GAX20847.1 - 3.8 8.0 13.5 3.5 8.2 1.1 4.0 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Prominin PF05478.11 GAX20847.1 - 4.1 5.2 9.6 5.4 4.9 8.8 1.4 1 1 1 2 2 2 0 Prominin DUF948 PF06103.11 GAX20847.1 - 4.4 7.6 9.1 3.4 8.0 0.8 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2408 PF10303.9 GAX20847.1 - 4.4 7.9 13.0 2.2e+03 -0.9 13.0 3.1 1 1 0 1 1 0 0 Protein of unknown function (DUF2408) Adaptin_binding PF10199.9 GAX20847.1 - 4.6 7.9 14.8 2.2e+02 2.4 12.9 3.8 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF3138 PF11336.8 GAX20847.1 - 4.6 5.7 5.4 9.8 4.7 5.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Syntaxin-6_N PF09177.11 GAX20847.1 - 5.2 7.7 15.7 9.3 6.9 5.3 3.4 1 1 1 3 3 3 0 Syntaxin 6, N-terminal Tup_N PF08581.10 GAX20847.1 - 5.3 7.4 12.9 12 6.3 2.7 4.3 2 2 1 3 3 3 0 Tup N-terminal Phage_HK97_TLTM PF06120.11 GAX20847.1 - 5.6 6.1 13.6 0.84 8.8 1.9 2.5 1 1 2 3 3 3 0 Tail length tape measure protein CheY-binding PF09078.11 GAX20847.1 - 5.8 7.1 5.8 6.3 7.0 0.2 3.4 4 0 0 4 4 3 0 CheY binding V_ATPase_I PF01496.19 GAX20847.1 - 7.1 4.4 11.0 1.4 6.7 0.9 2.1 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family CCDC106 PF15794.5 GAX20847.1 - 7.4 6.2 18.4 12 5.5 15.1 2.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 JIP_LZII PF16471.5 GAX20847.1 - 7.7 6.8 16.8 38 4.5 0.4 5.0 4 2 1 5 5 4 0 JNK-interacting protein leucine zipper II T2SSM PF04612.12 GAX20847.1 - 8.8 6.4 12.0 0.71 9.9 0.8 2.9 1 1 2 3 3 2 0 Type II secretion system (T2SS), protein M DUF5320 PF17253.2 GAX20847.1 - 9.1 7.4 6.3 52 5.0 0.4 3.4 1 1 1 3 3 3 0 Family of unknown function (DUF5320) Lzipper-MIP1 PF14389.6 GAX20847.1 - 9.4 6.6 12.6 1.7 9.0 4.8 3.5 2 2 2 4 4 3 0 Leucine-zipper of ternary complex factor MIP1 PAP_fibrillin PF04755.12 GAX20848.1 - 5e-05 23.3 2.8 0.027 14.4 0.1 2.1 2 0 0 2 2 2 2 PAP_fibrillin Cpn60_TCP1 PF00118.24 GAX20849.1 - 2.4e-139 465.2 5.5 2.7e-139 465.0 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ChiW_Ig_like PF18683.1 GAX20849.1 - 0.065 13.5 1.3 0.15 12.3 1.3 1.6 1 0 0 1 1 1 0 Chitinase W immunoglobulin-like domain zf-C2HC5 PF06221.13 GAX20850.1 - 2.4e-07 30.6 6.8 4.1e-07 29.9 6.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Leader_Erm PF08253.11 GAX20850.1 - 0.03 14.5 0.7 0.075 13.3 0.7 1.7 1 0 0 1 1 1 0 Erm Leader peptide 7tm_3 PF00003.22 GAX20851.1 - 2.5e-37 128.9 11.5 3.4e-37 128.4 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX20851.1 - 2.3e-32 112.6 0.0 3.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain 7tm_3 PF00003.22 GAX20852.1 - 1.3e-37 129.8 9.9 1.8e-37 129.3 9.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX20852.1 - 5.7e-35 121.1 0.0 8.2e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain FAD_binding_3 PF01494.19 GAX20853.1 - 4.5e-14 52.4 0.0 8.2e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAX20853.1 - 0.0021 18.6 0.1 0.0039 17.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX20853.1 - 0.0026 16.9 0.2 0.0044 16.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAX20853.1 - 0.0098 15.5 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX20853.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX20853.1 - 0.068 13.4 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LpxB PF02684.15 GAX20854.1 - 0.3 9.9 2.7 0.4 9.5 2.7 1.2 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Trypsin PF00089.26 GAX20855.1 - 2.2e-49 168.3 0.0 2.9e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX20855.1 - 0.0025 18.7 0.1 0.0086 17.0 0.1 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Helicase_C PF00271.31 GAX20856.1 - 8.9e-18 64.7 0.2 2.7e-16 59.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX20856.1 - 1.2e-16 61.0 0.0 6.7e-16 58.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase CarD_CdnL_TRCF PF02559.16 GAX20856.1 - 4.5e-15 56.1 0.0 2.6e-14 53.7 0.0 2.3 1 1 0 1 1 1 1 CarD-like/TRCF domain ResIII PF04851.15 GAX20856.1 - 0.00012 22.2 0.1 0.00057 19.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TRCF PF03461.15 GAX20856.1 - 0.023 15.1 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 TRCF domain MAPEG PF01124.18 GAX20857.1 - 1.9e-10 40.7 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 MAPEG family TMEM52 PF14979.6 GAX20858.1 - 0.0019 18.1 1.3 0.0026 17.7 0.9 1.5 1 1 0 1 1 1 1 Transmembrane 52 WBP-1 PF11669.8 GAX20858.1 - 0.14 12.8 2.4 0.17 12.5 0.5 2.1 1 1 1 2 2 2 0 WW domain-binding protein 1 LRR19-TM PF15176.6 GAX20858.1 - 0.22 11.5 4.0 3.2 7.8 0.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain Lactamase_B_2 PF12706.7 GAX20860.1 - 1.3e-10 41.2 0.0 9.3e-05 22.0 0.0 3.1 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX20860.1 - 7.6e-07 29.3 0.5 8.6e-06 25.9 0.1 2.7 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 GAX20860.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 tRNase Z endonuclease Mito_carr PF00153.27 GAX20861.1 - 4.2e-51 170.9 4.7 3.3e-16 59.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C48 PF02902.19 GAX20862.1 - 3.1e-24 86.0 1.2 5.2e-24 85.3 0.4 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain LRR_8 PF13855.6 GAX20863.1 - 2.1e-22 78.7 21.6 1.6e-05 24.6 0.2 5.3 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAX20863.1 - 5.4e-21 74.3 21.6 0.00049 20.4 1.2 5.3 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX20863.1 - 1.3e-09 37.3 23.5 2.5 9.0 0.1 9.5 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.6 GAX20863.1 - 0.32 11.2 17.6 2.7 8.3 0.2 6.8 8 0 0 8 8 8 0 Leucine Rich repeat DUF2110 PF09883.9 GAX20864.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) zf-GRF PF06839.12 GAX20865.1 - 7.2e-09 35.6 0.1 2.3e-08 34.0 0.1 2.0 1 0 0 1 1 1 1 GRF zinc finger E3_UbLigase_R4 PF13764.6 GAX20867.1 - 4.8e-88 296.3 0.0 5.1e-45 154.0 0.0 3.6 2 2 0 2 2 2 2 E3 ubiquitin-protein ligase UBR4 DUF3337 PF11816.8 GAX20867.1 - 0.017 15.0 0.1 0.057 13.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Radical_SAM PF04055.21 GAX20868.1 - 1.3e-21 77.7 0.0 3.2e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 GAX20868.1 - 8.6e-19 67.7 0.0 1.8e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 GAX20868.1 - 6e-10 39.5 0.0 6.7e-09 36.1 0.0 2.4 1 1 0 1 1 1 1 Flavodoxin GET2 PF08690.10 GAX20869.1 - 0.00014 21.7 2.7 0.00019 21.3 2.7 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 ABC2_membrane PF01061.24 GAX20870.1 - 7.1e-30 104.0 18.1 7.1e-30 104.0 18.1 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAX20870.1 - 5.4e-26 91.7 0.1 8.6e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX20870.1 - 1.2e-08 34.4 11.3 2.2e-08 33.6 11.3 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAX20870.1 - 0.00025 21.0 2.2 0.013 15.3 0.1 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAX20870.1 - 0.00025 21.0 0.0 0.00074 19.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GAX20870.1 - 0.0016 18.8 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAX20870.1 - 0.0021 17.5 0.5 0.06 12.8 0.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_35 PF14516.6 GAX20870.1 - 0.04 12.8 0.4 0.084 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain Rad17 PF03215.15 GAX20870.1 - 0.059 13.3 0.0 0.18 11.7 0.0 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 GAX20870.1 - 0.069 13.2 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 GAX20870.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX20870.1 - 0.11 12.8 0.2 0.26 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX20870.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAX20870.1 - 0.21 11.3 1.4 2 8.1 0.4 2.5 1 1 1 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 GAX20871.1 - 4e-58 195.8 0.0 1.4e-30 106.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 GAX20871.1 - 2.2e-51 175.0 24.0 2.4e-36 125.5 10.5 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 GAX20871.1 - 2.1e-15 57.3 0.0 0.00015 21.7 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAX20871.1 - 0.0003 21.3 4.4 0.0033 18.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAX20871.1 - 0.00079 19.8 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SRP54 PF00448.22 GAX20871.1 - 0.0011 18.7 6.4 0.23 11.1 0.2 3.1 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_22 PF13401.6 GAX20871.1 - 0.016 15.5 0.3 2.4 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 GAX20871.1 - 0.018 15.0 0.3 0.085 12.8 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 GAX20871.1 - 0.02 14.6 2.2 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 GAX20871.1 - 0.023 14.1 0.6 1.5 8.2 0.0 3.3 2 2 0 3 3 3 0 RecF/RecN/SMC N terminal domain MukB PF04310.12 GAX20871.1 - 0.027 14.3 3.4 1 9.1 0.5 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_29 PF13555.6 GAX20871.1 - 0.071 12.9 4.1 0.5 10.2 0.8 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.6 GAX20871.1 - 0.11 12.1 0.4 1.8 8.2 0.1 2.7 3 1 0 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.23 GAX20871.1 - 0.13 12.4 0.1 11 6.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 GAX20871.1 - 0.17 11.1 2.0 2.1 7.6 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin Glyco_hydro_3_C PF01915.22 GAX20872.1 - 4.2e-48 164.0 0.0 6.4e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAX20872.1 - 4.1e-41 141.4 0.0 6.2e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAX20872.1 - 2.2e-18 66.1 0.0 8.4e-18 64.3 0.0 2.1 1 0 0 1 1 1 1 Fibronectin type III-like domain Y_phosphatase3 PF13350.6 GAX20873.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Methyltransf_25 PF13649.6 GAX20874.1 - 0.011 16.4 0.0 0.02 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_17 PF12692.7 GAX20874.1 - 0.049 13.6 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_31 PF13847.6 GAX20874.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HYR PF02494.16 GAX20877.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.7 3 0 0 3 3 3 0 HYR domain Kinesin PF00225.23 GAX20878.1 - 3.3e-22 78.8 2.3 6.3e-22 77.9 0.0 2.6 3 1 0 3 3 3 1 Kinesin motor domain Phe_tRNA-synt_N PF02912.18 GAX20878.1 - 2.9 7.9 8.4 0.95 9.4 0.0 3.8 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF4455 PF14643.6 GAX20879.1 - 0.03 13.0 0.4 0.07 11.8 0.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) LRR_8 PF13855.6 GAX20880.1 - 5.9e-37 125.2 56.5 3.6e-06 26.6 1.2 12.7 9 4 5 15 15 15 13 Leucine rich repeat LRR_4 PF12799.7 GAX20880.1 - 3.3e-32 110.0 60.6 0.0084 16.5 0.1 15.6 10 5 5 17 17 17 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX20880.1 - 1.5e-10 40.1 36.4 3.7 8.5 0.1 15.8 17 1 0 17 17 17 4 Leucine Rich Repeat LRRNT_2 PF08263.12 GAX20880.1 - 0.00015 22.0 25.6 0.022 15.1 1.5 4.6 4 0 0 4 4 4 3 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 GAX20880.1 - 0.0097 15.9 42.1 3.3 8.0 0.1 13.3 15 0 0 15 15 15 4 Leucine Rich repeat ADH_zinc_N_2 PF13602.6 GAX20881.1 - 3.7e-15 57.1 0.0 2.7e-14 54.4 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAX20881.1 - 1e-10 41.7 0.0 2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX20881.1 - 0.0092 15.9 0.7 0.083 12.8 0.1 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAX20881.1 - 0.07 13.0 0.1 0.75 9.7 0.1 2.4 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase DUF2855 PF11017.8 GAX20881.1 - 0.092 12.5 0.0 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) FKBP_C PF00254.28 GAX20882.1 - 1.8e-17 63.4 0.0 2.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-C3HC4_3 PF13920.6 GAX20883.1 - 7.4e-10 38.5 7.7 7.4e-10 38.5 7.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX20883.1 - 1.5e-08 34.9 12.8 1.5e-08 34.9 12.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GAX20883.1 - 8.7e-08 31.9 11.5 8.7e-08 31.9 11.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX20883.1 - 1.1e-07 31.5 10.1 1.1e-07 31.5 10.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX20883.1 - 2.4e-07 30.9 9.5 2.4e-07 30.9 9.5 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAX20883.1 - 1.2e-06 28.2 8.0 1.2e-06 28.2 8.0 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAX20883.1 - 2e-06 27.7 5.8 5.3e-06 26.4 5.8 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX20883.1 - 1.8e-05 24.6 9.8 1.8e-05 24.6 9.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAX20883.1 - 0.0078 16.3 7.8 0.0078 16.3 7.8 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 GAX20883.1 - 0.075 13.2 6.3 0.42 10.8 4.6 2.5 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 GAX20883.1 - 0.1 12.7 7.4 0.28 11.2 6.4 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 GAX20883.1 - 0.16 12.1 7.1 0.07 13.3 4.3 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 GAX20883.1 - 0.21 11.4 15.2 0.048 13.5 10.9 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 GAX20883.1 - 0.38 10.4 14.2 0.2 11.3 10.0 2.4 2 1 0 2 2 2 0 P-11 zinc finger DZR PF12773.7 GAX20883.1 - 0.53 10.3 9.3 0.87 9.7 6.9 2.1 2 0 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 GAX20883.1 - 0.94 9.6 9.9 0.22 11.6 5.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) RAG1_imp_bd PF12560.8 GAX20883.1 - 4.4 6.8 12.0 1.1 8.7 8.7 1.6 1 1 1 2 2 2 0 RAG1 importin binding DUF1084 PF06454.11 GAX20884.1 - 0.001 18.5 12.6 0.0019 17.6 12.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) ABC2_membrane_3 PF12698.7 GAX20886.1 - 1.5e-55 188.7 23.9 1.4e-36 126.3 7.5 2.9 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 GAX20886.1 - 8.7e-53 178.5 0.0 2.5e-30 105.8 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAX20886.1 - 3.3e-15 56.7 0.0 3.9e-05 23.6 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX20886.1 - 0.00041 20.8 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 GAX20886.1 - 0.00067 19.1 1.2 0.94 8.9 0.0 3.7 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAX20886.1 - 0.01 15.7 0.4 0.023 14.6 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 GAX20886.1 - 0.012 16.1 0.1 0.012 16.1 0.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 GAX20886.1 - 0.022 15.1 0.1 2.9 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAX20886.1 - 0.025 14.6 0.0 0.33 11.1 0.1 2.5 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 GAX20886.1 - 0.064 13.0 0.7 0.82 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAX20886.1 - 0.2 11.4 1.0 0.83 9.4 0.4 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 GAX20886.1 - 0.38 10.4 3.8 3.7 7.1 1.4 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Amastin PF07344.11 GAX20887.1 - 1.3 8.9 15.0 0.14 12.0 9.9 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF2976 PF11190.8 GAX20887.1 - 7.6 6.4 7.9 2.7 7.9 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Myb_DNA-binding PF00249.31 GAX20888.1 - 9.3e-09 35.3 0.0 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain IL2 PF00715.17 GAX20888.1 - 0.14 12.1 1.6 0.3 11.0 1.6 1.6 1 0 0 1 1 1 0 Interleukin 2 Patatin PF01734.22 GAX20888.1 - 2 8.5 4.1 2.9 8.0 0.2 2.9 4 0 0 4 4 4 0 Patatin-like phospholipase AICARFT_IMPCHas PF01808.18 GAX20889.1 - 5e-83 279.0 2.0 6.2e-83 278.6 2.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 GAX20889.1 - 5.8e-24 84.1 0.0 1.2e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain zf-RING_2 PF13639.6 GAX20890.1 - 1.4e-10 41.3 11.2 2.5e-10 40.5 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX20890.1 - 1.4e-07 31.6 10.1 5e-07 29.9 10.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAX20890.1 - 4.5e-06 26.3 5.3 1.1e-05 25.1 5.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX20890.1 - 4.5e-05 23.2 9.8 4.5e-05 23.2 9.8 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX20890.1 - 8.6e-05 22.5 6.4 0.0002 21.3 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX20890.1 - 0.00014 21.6 8.3 0.00014 21.6 8.3 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX20890.1 - 0.0002 21.2 10.6 0.00029 20.6 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX20890.1 - 0.00038 20.0 5.9 0.00074 19.1 5.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAX20890.1 - 0.00046 20.1 8.9 0.001 19.0 8.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAX20890.1 - 0.0012 18.7 7.9 0.0021 17.9 7.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX20890.1 - 0.0027 17.7 6.2 0.0079 16.2 6.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAX20890.1 - 0.03 14.5 6.2 0.1 12.8 6.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 GAX20890.1 - 0.08 13.2 3.6 0.18 12.1 3.6 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_9 PF13901.6 GAX20890.1 - 0.14 12.1 5.8 0.29 11.1 5.8 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_6 PF14835.6 GAX20890.1 - 0.19 11.6 2.1 0.42 10.5 2.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF5531 PF17671.1 GAX20890.1 - 0.34 10.8 2.3 1 9.2 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5531) RINGv PF12906.7 GAX20890.1 - 0.45 10.7 10.1 0.95 9.6 10.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 GAX20890.1 - 4.2 7.5 6.9 0.39 10.8 2.1 1.8 2 0 0 2 2 1 0 Zinc-finger zf-RING-like PF08746.11 GAX20890.1 - 4.6 7.6 9.6 9.8 6.6 9.6 1.5 1 0 0 1 1 1 0 RING-like domain CxC6 PF18721.1 GAX20892.1 - 0.0015 18.8 18.5 0.17 12.2 3.2 3.7 1 1 2 3 3 3 3 CxC6 like cysteine cluster associated with KDZ transposases DnaJ PF00226.31 GAX20893.1 - 0.0014 18.7 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_C13 PF01650.18 GAX20894.1 - 8.1e-40 137.0 0.4 1.1e-39 136.5 0.4 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF924 PF06041.11 GAX20895.1 - 8.7e-40 136.8 0.0 1e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) FIN1 PF17300.2 GAX20897.1 - 0.12 11.8 1.1 0.46 10.0 0.1 1.8 2 0 0 2 2 2 0 Filaments in between nuclei protein-1 Abhydrolase_1 PF00561.20 GAX20898.1 - 4.7e-06 26.4 0.3 1.9e-05 24.4 0.2 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Endonuc-MspI PF09208.10 GAX20899.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease MspI 2TM PF13239.6 GAX20900.1 - 0.003 17.8 0.1 0.018 15.3 0.5 2.0 2 0 0 2 2 2 1 2TM domain TMEM171 PF15471.6 GAX20901.1 - 0.15 11.0 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Pkinase PF00069.25 GAX20902.1 - 5.8e-28 98.0 0.0 7.2e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX20902.1 - 2.6e-17 63.0 0.0 3.3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX20902.1 - 2.6e-09 36.3 0.1 3.6e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX20902.1 - 0.00067 19.6 0.0 0.005 16.8 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAX20902.1 - 0.12 11.4 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TLD PF07534.16 GAX20903.1 - 7.9e-13 48.8 0.0 1.5e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 TLD zf-UBR PF02207.20 GAX20904.1 - 3.8e-18 65.4 18.4 9.4e-18 64.2 18.4 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAX20904.1 - 0.00076 19.2 3.0 0.022 14.5 3.0 2.7 1 1 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF1484 PF07363.11 GAX20904.1 - 0.06 14.4 0.5 0.27 12.3 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Gly-zipper_YMGG PF13441.6 GAX20904.1 - 0.7 9.7 7.6 1.9 8.3 7.6 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper RRM_1 PF00076.22 GAX20905.1 - 4.4e-67 221.8 0.0 5.8e-18 64.5 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAX20905.1 - 1.5e-12 47.2 0.0 2.2e-05 24.2 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GAX20905.1 - 9.4e-10 38.4 1.0 0.12 12.4 0.0 4.4 4 0 0 4 4 4 3 Limkain b1 RRM_3 PF08777.11 GAX20905.1 - 8e-09 35.5 0.5 0.015 15.3 0.1 4.4 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 GAX20905.1 - 2e-06 27.7 0.3 7.2e-05 22.7 0.1 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAX20905.1 - 0.00088 19.4 0.0 3.2 7.9 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 GAX20905.1 - 0.0011 18.6 0.0 11 5.7 0.0 3.7 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 GAX20905.1 - 0.0016 18.2 0.0 0.53 10.1 0.0 3.5 4 0 0 4 4 4 1 Rrp7 RRM-like N-terminal domain DUF3343 PF11823.8 GAX20905.1 - 0.13 11.8 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) DUF2542 PF10808.8 GAX20906.1 - 0.1 13.1 0.4 0.35 11.4 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2542) Methyltransf_16 PF10294.9 GAX20907.1 - 1.4e-17 63.9 0.1 2.1e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAX20907.1 - 1.5e-05 25.6 0.2 2.8e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20907.1 - 5.9e-05 23.7 0.1 0.00017 22.3 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX20907.1 - 7.9e-05 23.2 0.2 0.00027 21.5 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX20907.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX20907.1 - 0.0008 19.0 0.2 0.0019 17.8 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX20907.1 - 0.0082 16.0 0.3 0.012 15.5 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX20907.1 - 0.0088 15.8 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 GAX20907.1 - 0.02 14.6 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 GAX20907.1 - 0.11 11.8 0.2 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Radical_SAM PF04055.21 GAX20908.1 - 6.7e-10 39.6 0.0 1.1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 GAX20908.1 - 9.1e-09 35.7 0.0 3.7e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Rubis-subs-bind PF09273.11 GAX20909.1 - 1.3e-08 35.6 1.5 3.4e-08 34.2 1.3 1.8 3 0 0 3 3 3 1 Rubisco LSMT substrate-binding SET PF00856.28 GAX20909.1 - 3.7e-07 30.7 0.0 2.4e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 SET domain DNA_ligase_OB PF03120.16 GAX20909.1 - 0.17 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain WHAMM-JMY_N PF15920.5 GAX20910.1 - 0.054 13.4 0.1 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated LRR_4 PF12799.7 GAX20910.1 - 0.26 11.8 3.0 19 5.9 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) GATase_6 PF13522.6 GAX20911.1 - 4.6e-11 43.0 0.1 1e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX20911.1 - 4.1e-10 39.6 0.0 1.1e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 GAX20911.1 - 5.4e-07 29.3 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TRM13 PF05206.14 GAX20912.1 - 4.9e-37 127.9 0.0 7.3e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 GAX20912.1 - 6.6e-11 41.8 5.1 1.3e-10 40.9 5.1 1.5 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 GAX20912.1 - 9.6e-08 31.8 0.4 9.6e-08 31.8 0.4 2.7 3 0 0 3 3 3 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 GAX20912.1 - 0.00034 20.7 0.2 0.00079 19.4 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fusion_gly_K PF01621.17 GAX20912.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Cell fusion glycoprotein K Methyltransf_16 PF10294.9 GAX20912.1 - 0.071 12.8 0.4 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Lysine methyltransferase MULE PF10551.9 GAX20913.1 - 1.5e-05 25.3 0.0 4.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Ribosomal_L32e PF01655.18 GAX20915.1 - 1.1e-45 154.4 0.3 1.4e-45 154.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 TPR_12 PF13424.6 GAX20916.1 - 3.3e-50 168.3 7.1 1.3e-10 41.4 0.1 6.2 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 GAX20916.1 - 2.7e-25 87.4 7.4 0.0038 17.0 0.2 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX20916.1 - 1.5e-19 68.4 24.2 4.2e-05 23.3 0.2 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20916.1 - 4.1e-16 57.8 23.0 0.0025 17.9 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX20916.1 - 6.3e-15 54.0 6.2 0.26 11.4 0.0 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX20916.1 - 9.6e-14 51.5 2.6 4e-07 29.7 0.4 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 GAX20916.1 - 1e-12 47.3 24.8 0.0013 18.5 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAX20916.1 - 9.2e-12 45.4 4.4 0.36 11.5 0.0 6.7 7 1 1 8 8 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAX20916.1 - 1.3e-11 44.2 12.9 0.016 16.0 0.1 8.1 8 2 2 10 10 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX20916.1 - 2.1e-09 37.8 8.7 0.04 14.4 0.2 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.6 GAX20916.1 - 8.3e-09 35.3 17.0 0.026 13.9 2.3 5.0 3 2 1 5 5 5 4 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 GAX20916.1 - 3.3e-08 33.3 1.6 0.7 10.4 0.0 6.6 8 0 0 8 8 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX20916.1 - 0.0014 18.1 0.5 0.84 9.1 0.0 3.3 3 0 0 3 3 3 1 SHNi-TPR TPR_15 PF13429.6 GAX20916.1 - 0.002 17.4 3.5 0.014 14.7 0.6 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX20916.1 - 0.0021 17.7 12.4 2.2 8.1 0.1 5.3 5 0 0 5 5 5 2 TPR repeat RPN7 PF10602.9 GAX20916.1 - 0.0027 17.4 9.5 0.99 9.1 4.1 4.8 2 2 1 3 3 3 1 26S proteasome subunit RPN7 BTAD PF03704.17 GAX20916.1 - 0.0029 18.1 0.2 18 5.8 0.0 3.8 4 0 0 4 4 3 0 Bacterial transcriptional activator domain DUF2225 PF09986.9 GAX20916.1 - 0.0043 16.8 9.0 2.7 7.7 0.1 4.1 1 1 2 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 GAX20916.1 - 0.0058 17.2 19.3 0.95 10.2 0.2 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF627 PF04781.12 GAX20916.1 - 0.042 13.9 14.1 4.4 7.4 0.3 5.0 3 2 1 4 4 4 0 Protein of unknown function (DUF627) TPR_4 PF07721.14 GAX20916.1 - 0.072 13.8 0.0 37 5.3 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_H7 PF04787.12 GAX20916.1 - 0.14 12.7 1.8 3 8.3 0.0 3.2 3 0 0 3 3 3 0 Late protein H7 PPR PF01535.20 GAX20916.1 - 0.27 11.5 1.2 12 6.4 0.0 4.1 5 0 0 5 5 2 0 PPR repeat ANAPC5 PF12862.7 GAX20916.1 - 0.49 10.5 5.9 18 5.5 0.0 3.8 5 0 0 5 5 4 0 Anaphase-promoting complex subunit 5 NRBF2_MIT PF17169.4 GAX20916.1 - 0.59 10.4 3.3 21 5.4 0.0 4.0 4 0 0 4 4 3 0 MIT domain of nuclear receptor-binding factor 2 Ribosomal_S19e PF01090.19 GAX20917.1 - 1.9e-53 179.8 0.0 2.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e BRX_N PF13713.6 GAX20917.1 - 0.011 15.4 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Aminotran_4 PF01063.19 GAX20918.1 - 8.4e-12 45.4 0.0 2.1e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV UCH PF00443.29 GAX20918.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HSP70 PF00012.20 GAX20919.1 - 2.4e-251 835.2 3.1 2.8e-251 835.0 3.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX20919.1 - 9.8e-20 70.6 0.3 1.8e-18 66.5 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 GAX20919.1 - 0.00064 19.1 4.2 0.0012 18.2 4.2 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 FtsA PF14450.6 GAX20919.1 - 0.022 15.2 2.9 4.7 7.7 0.0 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 GAX20919.1 - 0.036 13.3 0.1 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 GAX20919.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain TRAF_BIRC3_bd PF16673.5 GAX20919.1 - 2.6 7.9 5.6 1.2 9.0 1.5 2.5 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Aldo_ket_red PF00248.21 GAX20920.1 - 3e-39 135.0 0.0 4.8e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family PRAI PF00697.22 GAX20920.1 - 0.073 12.8 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase PAXNEB PF05625.11 GAX20922.1 - 2.9e-34 118.8 0.0 6.5e-33 114.4 0.0 2.6 1 1 0 1 1 1 1 PAXNEB protein DUF3648 PF12364.8 GAX20922.1 - 0.11 12.7 0.6 0.24 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) Acetyltransf_1 PF00583.25 GAX20923.1 - 4.2e-09 36.6 0.1 1.3e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX20923.1 - 1.4e-06 28.6 0.0 1.5e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX20923.1 - 0.00093 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SNase PF00565.17 GAX20924.1 - 1.3e-25 90.0 0.1 1.7e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Thioredoxin PF00085.20 GAX20925.1 - 2.4e-25 88.5 0.9 5.3e-25 87.4 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX20925.1 - 0.00036 21.0 0.0 0.00089 19.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 GAX20925.1 - 0.0043 17.0 0.0 0.056 13.4 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain CdiI_2 PF18593.1 GAX20925.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 CdiI immunity protein TraF PF13728.6 GAX20925.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein ERp29 PF07749.12 GAX20925.1 - 0.029 15.3 0.1 0.058 14.3 0.1 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.6 GAX20925.1 - 0.043 14.0 0.0 0.091 12.9 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 GAX20925.1 - 0.097 12.4 0.1 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Redoxin OST3_OST6 PF04756.13 GAX20925.1 - 0.097 12.0 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family AphA_like PF14557.6 GAX20925.1 - 0.29 10.8 0.8 0.35 10.6 0.1 1.5 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator HECT PF00632.25 GAX20926.1 - 6.7e-88 295.1 0.0 1.2e-87 294.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NUDIX PF00293.28 GAX20927.1 - 1.6e-11 44.3 0.4 3.5e-11 43.3 0.2 1.7 2 0 0 2 2 2 1 NUDIX domain Methyltransf_16 PF10294.9 GAX20928.1 - 3.8e-16 59.3 0.0 6.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAX20928.1 - 0.017 15.8 0.0 0.034 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAX20928.1 - 0.037 13.6 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX20928.1 - 0.15 12.8 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PI3_PI4_kinase PF00454.27 GAX20930.1 - 1.2e-24 87.5 0.0 2.2e-23 83.4 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PX PF00787.24 GAX20930.1 - 0.12 12.4 0.5 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 PX domain tRNA-synt_1 PF00133.22 GAX20931.1 - 7.6e-205 681.7 0.0 8.8e-204 678.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAX20931.1 - 8.9e-37 126.4 0.0 1.6e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAX20931.1 - 8.5e-24 84.0 0.0 1.2e-08 34.1 0.0 3.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 GAX20931.1 - 1.2e-18 67.2 6.5 2.6e-18 66.0 6.5 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 GAX20931.1 - 3.8e-13 49.4 0.0 5.9e-10 39.0 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAX20931.1 - 0.026 13.9 0.0 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GAX20931.1 - 0.053 12.4 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) ABC_tran_CTD PF16326.5 GAX20931.1 - 0.13 12.5 3.3 0.59 10.4 3.3 2.1 1 0 0 1 1 1 0 ABC transporter C-terminal domain tRNA-synt_1b PF00579.25 GAX20931.1 - 0.19 11.0 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF4140 PF13600.6 GAX20931.1 - 8.4 6.9 6.1 25 5.4 0.8 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SelR PF01641.18 GAX20932.1 - 0.0069 16.5 0.2 0.095 12.8 0.2 2.6 1 1 0 1 1 1 1 SelR domain EamA PF00892.20 GAX20933.1 - 1.7e-05 25.0 13.8 2.4e-05 24.5 13.8 1.2 1 0 0 1 1 1 1 EamA-like transporter family Fuseless PF15993.5 GAX20934.1 - 1e-13 51.2 1.4 3.4e-13 49.5 1.4 1.7 1 1 0 1 1 1 1 Fuseless Arginase PF00491.21 GAX20935.1 - 1.6e-76 257.5 0.0 2e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family Glyco_hydro81C PF17652.1 GAX20936.1 - 4.4e-65 220.2 1.4 6.8e-65 219.6 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAX20936.1 - 2.2e-30 106.0 0.1 9.9e-19 67.7 0.0 2.6 1 1 1 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain SLAC1 PF03595.17 GAX20936.1 - 0.014 14.7 0.2 0.022 14.0 0.2 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel Coatomer_E PF04733.14 GAX20937.1 - 3.3e-54 184.3 0.4 3.8e-54 184.1 0.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 GAX20937.1 - 0.00047 20.6 14.9 0.75 10.4 0.0 5.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX20937.1 - 0.00096 19.0 0.5 0.24 11.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX20937.1 - 0.005 16.8 7.5 0.053 13.6 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX20937.1 - 0.0081 16.9 11.3 1.2 10.2 0.1 5.4 2 2 4 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX20937.1 - 0.062 14.0 4.9 0.32 11.7 0.0 3.8 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX20937.1 - 0.24 11.3 6.3 4.1 7.4 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX20937.1 - 1.7 9.4 0.0 1.7 9.4 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX20937.1 - 2.4 8.6 7.7 42 4.7 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Rhomboid PF01694.22 GAX20938.1 - 3.5e-24 85.5 5.9 4.1e-24 85.3 5.9 1.1 1 0 0 1 1 1 1 Rhomboid family GHMP_kinases_N PF00288.26 GAX20939.1 - 9.5e-13 48.2 2.2 9.5e-13 48.2 2.2 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAX20939.1 - 4.1e-05 23.9 0.0 0.00014 22.1 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal DUF3523 PF12037.8 GAX20940.1 - 3.3e-86 288.9 27.0 5.8e-86 288.2 27.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 GAX20940.1 - 1.9e-21 76.9 0.0 4.9e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX20940.1 - 5.9e-05 22.9 0.0 0.0002 21.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX20940.1 - 0.00021 21.3 4.3 0.0035 17.3 0.2 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX20940.1 - 0.00072 19.8 2.9 0.012 15.9 0.0 3.3 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 GAX20940.1 - 0.0013 18.2 0.0 0.0038 16.6 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GAX20940.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 3.6 2 2 1 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 GAX20940.1 - 0.0033 17.6 0.0 0.0033 17.6 0.0 4.1 4 1 1 5 5 4 1 AAA domain NACHT PF05729.12 GAX20940.1 - 0.0076 16.2 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 GAX20940.1 - 0.008 16.7 2.7 0.077 13.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 GAX20940.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 GAX20940.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 GAX20940.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Borrelia_P83 PF05262.11 GAX20940.1 - 0.064 11.8 20.7 0.093 11.2 20.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_24 PF13479.6 GAX20940.1 - 0.072 12.8 1.6 0.11 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAX20940.1 - 0.091 12.5 0.0 0.091 12.5 0.0 2.9 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 GAX20940.1 - 0.19 12.1 0.0 0.57 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 GAX20940.1 - 0.24 10.9 0.1 0.24 10.9 0.1 2.4 2 1 0 2 2 2 0 AAA domain CDK5_activator PF03261.15 GAX20940.1 - 0.82 9.2 9.6 1.3 8.5 9.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein NMO PF03060.15 GAX20941.1 - 3.4e-55 187.7 5.6 2.8e-52 178.2 5.6 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAX20941.1 - 6.5e-14 51.7 3.1 1.8e-13 50.2 3.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAX20941.1 - 2e-11 43.5 4.1 2.7e-11 43.1 4.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 GAX20941.1 - 0.00044 19.6 7.0 0.0015 17.9 7.0 1.7 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAX20941.1 - 0.019 14.4 0.3 0.033 13.7 0.3 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.17 GAX20941.1 - 0.61 9.1 8.9 3.6 6.6 6.4 2.4 2 1 0 2 2 2 0 Conserved region in glutamate synthase PPR_2 PF13041.6 GAX20942.1 - 2.9e-10 40.2 1.4 1.7e-07 31.3 0.1 4.4 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.20 GAX20942.1 - 9.9e-08 31.7 11.7 0.0016 18.6 0.1 5.9 7 1 1 8 8 8 2 PPR repeat Methyltransf_4 PF02390.17 GAX20942.1 - 1.1e-07 31.5 0.0 2.8e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 Putative methyltransferase PPR_long PF17177.4 GAX20942.1 - 1.5e-05 24.4 4.6 0.0063 15.9 1.1 2.6 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GAX20942.1 - 3.1e-05 24.4 0.2 2.8 9.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR_1 PF12854.7 GAX20942.1 - 3.4e-05 23.4 11.2 0.26 11.0 0.0 4.8 6 0 0 6 6 6 3 PPR repeat TPR_19 PF14559.6 GAX20942.1 - 0.00077 19.9 3.1 0.44 11.1 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat PPR_3 PF13812.6 GAX20942.1 - 0.0091 16.1 0.1 0.033 14.3 0.1 1.9 1 1 1 2 2 2 1 Pentatricopeptide repeat domain TPR_2 PF07719.17 GAX20942.1 - 0.015 15.4 2.3 18 5.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX20942.1 - 0.024 15.2 0.3 2.3 9.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 GAX20942.1 - 0.027 14.9 0.5 0.7 10.3 0.5 2.6 1 1 0 1 1 1 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 GAX20942.1 - 3.9 7.8 6.1 10 6.5 0.3 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PRKG1_interact PF15898.5 GAX20942.1 - 9.1 7.2 16.0 0.29 12.1 5.6 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain tRNA-synt_1e PF01406.19 GAX20945.1 - 2.2e-83 280.1 0.0 2.9e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAX20945.1 - 0.00084 18.2 0.0 0.022 13.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (M) NPR1_interact PF15699.5 GAX20945.1 - 0.023 15.3 0.2 2.3 8.9 0.1 2.5 2 0 0 2 2 2 0 NPR1 interacting Cytochrom_C_2 PF01322.20 GAX20945.1 - 0.093 13.6 0.0 1.4 9.8 0.0 2.6 2 0 0 2 2 2 0 Cytochrome C' tRNA-synt_1 PF00133.22 GAX20945.1 - 0.12 10.6 0.0 0.2 9.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) HSF_DNA-bind PF00447.17 GAX20946.1 - 5e-15 55.9 0.1 8.7e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding TPR_19 PF14559.6 GAX20947.1 - 0.084 13.4 3.7 2.7 8.6 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX20947.1 - 0.1 12.3 0.4 6.4 6.5 0.1 2.9 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 GAX20947.1 - 0.66 10.9 6.1 23 6.2 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPMT PF05724.11 GAX20948.1 - 6.2e-43 147.0 0.0 7.7e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 GAX20948.1 - 0.00033 21.2 0.0 0.00063 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX20948.1 - 0.0011 19.6 0.0 0.0041 17.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX20948.1 - 0.002 18.0 0.0 0.0042 16.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX20948.1 - 0.08 13.7 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 GAX20948.1 - 0.098 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Rhomboid PF01694.22 GAX20949.1 - 5.1e-20 72.0 16.8 5.1e-20 72.0 16.8 1.5 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 GAX20949.1 - 0.0014 19.1 0.8 0.0042 17.6 0.2 2.1 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) ZYG-11_interact PF05884.12 GAX20949.1 - 0.06 12.8 7.7 0.096 12.1 5.1 2.1 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF1275 PF06912.11 GAX20949.1 - 0.18 11.7 10.7 1.3 9.0 10.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) DUF4149 PF13664.6 GAX20949.1 - 0.36 11.2 6.5 0.33 11.3 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) LapA_dom PF06305.11 GAX20949.1 - 3.7 7.4 0.0 3.7 7.4 0.0 3.3 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Peptidase_C1 PF00112.23 GAX20951.1 - 3.2e-36 125.5 0.1 3e-34 119.0 0.1 2.1 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAX20951.1 - 0.046 12.5 0.5 0.22 10.3 0.2 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Herpes_ICP4_N PF03584.15 GAX20951.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Chorismate_synt PF01264.21 GAX20952.1 - 2.3e-136 453.8 0.5 2.7e-136 453.6 0.5 1.0 1 0 0 1 1 1 1 Chorismate synthase ThiF PF00899.21 GAX20952.1 - 0.04 13.3 0.1 0.062 12.6 0.1 1.3 1 0 0 1 1 1 0 ThiF family DUF1573 PF07610.11 GAX20952.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) PH PF00169.29 GAX20954.1 - 0.0008 19.9 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 PH domain FAD_binding_3 PF01494.19 GAX20955.1 - 5.6e-18 65.3 0.0 1.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAX20955.1 - 0.00028 21.1 0.1 0.00061 20.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAX20955.1 - 0.0056 17.2 0.1 0.098 13.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX20955.1 - 0.016 14.5 0.7 0.098 11.9 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 GAX20955.1 - 0.017 14.4 0.1 0.07 12.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX20955.1 - 0.028 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pkinase PF00069.25 GAX20956.1 - 9.6e-64 215.3 0.2 1.1e-63 215.1 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX20956.1 - 6.4e-18 65.0 0.0 9.4e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX20956.1 - 4e-06 26.9 0.0 1.4e-05 25.2 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX20956.1 - 0.021 13.6 0.1 0.072 11.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 GAX20956.1 - 0.023 14.0 0.2 0.039 13.3 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAX20956.1 - 0.027 14.0 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.8 GAX20956.1 - 0.097 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain DUF2459 PF09601.10 GAX20956.1 - 0.099 12.4 0.0 0.93 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) TAP42 PF04177.12 GAX20957.1 - 3.2e-50 171.1 11.0 3.8e-50 170.8 11.0 1.0 1 0 0 1 1 1 1 TAP42-like family NOA36 PF06524.12 GAX20957.1 - 0.16 11.3 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 NOA36 protein NIF PF03031.18 GAX20958.1 - 1.4e-24 86.7 0.1 2.3e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 GAX20958.1 - 0.067 13.0 0.3 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin family NUDIX PF00293.28 GAX20959.1 - 1.8e-11 44.2 0.0 5.9e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Hydrolase_like PF13242.6 GAX20959.1 - 0.0099 15.9 0.0 0.028 14.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX20959.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2388 PF09498.10 GAX20960.1 - 1.3e-06 28.3 33.0 39 4.3 0.0 25.0 37 0 0 37 37 37 0 Protein of unknown function (DUF2388) DUF4620 PF15399.6 GAX20960.1 - 0.00012 22.4 6.6 9.9 6.5 0.0 10.4 12 1 1 13 13 13 1 Domain of unknown function (DUF4620) KIX_2 PF16987.5 GAX20960.1 - 0.00022 21.1 0.1 70 3.5 0.0 9.5 11 0 0 11 11 11 0 KIX domain hnRNP_Q_AcD PF18360.1 GAX20960.1 - 0.00085 19.2 0.0 74 3.4 0.0 9.8 12 0 0 12 12 12 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Maelstrom PF13017.6 GAX20960.1 - 0.00098 18.8 0.0 2.5 7.7 0.1 7.1 9 1 0 9 9 9 1 piRNA pathway germ-plasm component FGGY_C PF02782.16 GAX20960.1 - 0.022 14.5 0.0 57 3.4 0.0 6.8 4 0 0 4 4 4 0 FGGY family of carbohydrate kinases, C-terminal domain DUF3006 PF11213.8 GAX20960.1 - 0.07 13.4 1.0 0.35 11.1 1.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Slx4 PF09494.10 GAX20960.1 - 0.088 12.8 16.8 1.8e+02 2.2 0.0 15.1 22 0 0 22 22 22 0 Slx4 endonuclease Kinesin PF00225.23 GAX20961.1 - 4.2e-51 173.8 0.0 1.6e-50 171.9 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX20961.1 - 5.6e-17 62.0 0.0 2e-16 60.3 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Med30 PF11315.8 GAX20961.1 - 3 8.0 10.2 13 6.0 1.8 3.1 2 0 0 2 2 2 0 Mediator complex subunit 30 RRM_1 PF00076.22 GAX20962.1 - 9.5e-27 92.6 0.0 2.1e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX20962.1 - 4.4e-06 26.7 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 GAX20962.1 - 0.00024 21.4 0.7 0.00024 21.4 0.7 2.4 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 GAX20962.1 - 0.062 13.3 0.2 3 7.9 0.0 2.7 2 1 0 2 2 2 0 RL domain Rhodanese_C PF12368.8 GAX20963.1 - 3.4e-12 46.6 8.1 3.4e-12 46.6 8.1 1.9 2 0 0 2 2 2 1 Rhodanase C-terminal UPF0176_N PF17773.1 GAX20963.1 - 4.1e-06 27.1 0.0 1.2e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GAX20963.1 - 0.00013 22.4 0.0 0.00029 21.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-CCCH_2 PF14608.6 GAX20963.1 - 0.00027 21.3 3.4 0.00071 19.9 3.4 1.8 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger DUF5075 PF16825.5 GAX20963.1 - 0.075 12.7 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 IGP family C-type lectin domain MAS20 PF02064.15 GAX20963.1 - 0.5 10.5 3.1 5.4 7.1 1.6 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor FYVE PF01363.21 GAX20963.1 - 0.67 10.1 9.6 1.9 8.7 9.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger Pro_isomerase PF00160.21 GAX20964.1 - 0.031 14.6 0.0 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc82 PF05645.13 GAX20964.1 - 0.22 11.2 3.9 7.3 6.3 3.5 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Pannexin_like PF12534.8 GAX20964.1 - 0.32 10.0 3.4 0.44 9.6 2.9 1.4 1 1 0 1 1 1 0 Pannexin-like TM region of LRRC8 RNA_pol_A_bac PF01000.26 GAX20965.1 - 1.4e-23 83.3 0.0 4.4e-23 81.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAX20965.1 - 6.9e-21 73.5 0.0 9.5e-21 73.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain OB_RNB PF08206.11 GAX20965.1 - 0.029 14.0 0.1 0.62 9.8 0.0 2.7 3 0 0 3 3 3 0 Ribonuclease B OB domain RNA_pol_L_2 PF13656.6 GAX20965.1 - 0.049 13.4 0.1 0.95 9.3 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2312 PF10073.9 GAX20966.1 - 0.0023 17.5 2.9 0.0063 16.1 2.9 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) LETM1 PF07766.13 GAX20966.1 - 0.0023 17.3 4.2 0.009 15.4 0.1 2.2 1 1 1 2 2 2 1 LETM1-like protein FPP PF05911.11 GAX20966.1 - 0.0029 15.9 6.6 0.0037 15.5 6.6 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil MscS_porin PF12795.7 GAX20966.1 - 0.011 15.3 7.0 0.011 15.3 7.0 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain THOC7 PF05615.13 GAX20966.1 - 0.013 15.7 2.4 0.013 15.7 2.4 1.7 2 0 0 2 2 1 0 Tho complex subunit 7 GAS PF13851.6 GAX20966.1 - 0.014 14.8 4.9 0.026 13.9 4.9 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3899 PF13038.6 GAX20966.1 - 0.025 15.1 0.2 0.29 11.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) NUDE_C PF04880.13 GAX20966.1 - 0.034 14.6 1.9 0.045 14.2 1.9 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ANTH PF07651.16 GAX20966.1 - 0.053 12.5 2.1 0.093 11.7 1.3 1.6 1 1 0 2 2 2 0 ANTH domain Herpes_UL6 PF01763.16 GAX20966.1 - 0.063 11.8 1.7 0.077 11.5 1.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Mur_ligase PF01225.25 GAX20966.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, catalytic domain AAA_23 PF13476.6 GAX20966.1 - 0.27 11.7 2.9 0.44 11.0 2.9 1.4 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.11 GAX20966.1 - 0.28 11.6 4.4 13 6.3 3.0 3.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) KELK PF15796.5 GAX20966.1 - 0.45 11.0 7.6 1.5 9.3 7.6 2.0 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APG6_N PF17675.1 GAX20966.1 - 1.6 9.3 13.9 2.7 8.5 13.8 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4337 PF14235.6 GAX20966.1 - 2.3 8.3 5.9 0.4 10.8 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Lactamase_B_2 PF12706.7 GAX20967.1 - 7e-20 71.4 1.3 4.2e-17 62.3 0.2 3.2 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX20967.1 - 3.1e-10 40.4 1.1 0.0003 20.9 0.0 2.8 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 GAX20967.1 - 8.4e-09 35.0 0.0 3.1e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_6 PF16661.5 GAX20967.1 - 0.00015 21.3 0.0 0.51 9.7 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain DNA_pol_A_exo1 PF01612.20 GAX20968.1 - 1.9e-33 115.7 1.0 3.2e-33 114.9 1.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 GAX20968.1 - 5.2e-10 39.2 0.1 1.6e-09 37.6 0.1 1.9 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 GAX20968.1 - 7e-09 36.3 6.6 7.4e-09 36.2 0.3 3.4 3 0 0 3 3 3 1 PMC2NT (NUC016) domain Ribosomal_S9 PF00380.19 GAX20969.1 - 5.4e-43 146.4 0.0 8.3e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 IML1 PF12257.8 GAX20970.1 - 3.9e-87 292.0 0.0 6.4e-87 291.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DUF4279 PF14106.6 GAX20970.1 - 0.052 13.7 0.0 0.43 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) AalphaY_MDB PF04611.12 GAX20971.1 - 0.017 15.2 0.1 0.074 13.1 0.1 2.1 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region LRR_8 PF13855.6 GAX20972.1 - 1.7e-12 46.9 7.2 0.00023 20.8 0.1 4.1 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 GAX20972.1 - 4.4e-10 39.7 2.8 0.0023 18.3 0.1 4.4 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX20972.1 - 2.2e-05 24.4 2.0 0.89 10.3 0.1 5.6 5 1 1 6 6 6 1 Leucine Rich Repeat Glyco_hydr_30_2 PF14587.6 GAX20972.1 - 0.12 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 FtsK_4TM PF13491.6 GAX20973.1 - 0.53 10.0 3.7 0.14 11.8 0.6 1.6 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Nup54 PF13874.6 GAX20974.1 - 1e-21 77.5 6.3 1e-21 77.5 6.3 1.8 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 GAX20974.1 - 5e-07 30.5 47.7 11 7.0 47.7 3.1 1 1 0 1 1 1 1 Nucleoporin FG repeat region Nup88 PF10168.9 GAX20974.1 - 0.002 16.1 4.0 0.0028 15.5 4.0 1.1 1 0 0 1 1 1 1 Nuclear pore component Lge1 PF11488.8 GAX20974.1 - 0.083 13.1 0.5 0.25 11.5 0.5 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF4201 PF13870.6 GAX20974.1 - 0.59 9.9 6.8 0.3 10.8 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) BRE1 PF08647.11 GAX20974.1 - 2.8 8.1 6.7 1.5 9.0 1.9 2.6 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase LNS2 PF08235.13 GAX20975.1 - 2.5e-29 102.4 0.0 3.6e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) RSN1_7TM PF02714.15 GAX20976.1 - 7.2e-51 173.1 18.0 1.6e-50 172.0 18.0 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX20976.1 - 2.4e-28 98.8 2.5 2.4e-28 98.8 2.5 3.5 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX20976.1 - 1.4e-19 71.0 0.0 1.5e-12 48.1 0.0 2.9 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter DUF501 PF04417.12 GAX20977.1 - 8.3e-29 100.2 0.7 2e-28 98.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF501) MAGE_N PF12440.8 GAX20977.1 - 0.31 11.7 4.4 0.13 12.9 1.1 2.0 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Amidohydro_2 PF04909.14 GAX20979.1 - 2.3e-35 122.8 0.1 2.9e-35 122.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase THF_DHG_CYH PF00763.23 GAX20979.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain RRM_1 PF00076.22 GAX20980.1 - 9.7e-21 73.4 0.0 1.4e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 GAX20980.1 - 7.1e-09 36.2 8.1 1.6e-08 35.1 8.1 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 GAX20980.1 - 0.17 12.1 0.0 0.53 10.4 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif WD40 PF00400.32 GAX20981.1 - 9.8e-20 70.5 26.2 1.1e-06 29.2 1.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 GAX20981.1 - 4.8e-10 39.8 0.1 9.5e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 GAX20981.1 - 0.00041 20.6 1.6 0.42 10.9 0.3 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX20981.1 - 0.0071 16.8 0.3 3.4 8.3 0.0 3.8 4 0 0 4 4 4 1 PQQ-like domain VIT_2 PF13757.6 GAX20981.1 - 0.1 12.5 0.3 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Vault protein inter-alpha-trypsin domain PPR_2 PF13041.6 GAX20982.1 - 3.1e-06 27.3 0.0 0.0025 18.0 0.0 4.3 4 0 0 4 4 4 1 PPR repeat family Nop PF01798.18 GAX20983.1 - 1.3e-56 191.7 0.0 1.7e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 GAX20983.1 - 3.1e-16 60.4 1.1 7.3e-16 59.2 1.1 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain GST_C_3 PF14497.6 GAX20984.1 - 2.2e-15 56.7 0.5 3.9e-15 55.8 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX20984.1 - 0.00043 20.3 0.0 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX20984.1 - 0.021 15.1 0.2 0.039 14.2 0.2 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TIM PF00121.18 GAX20985.1 - 1.6e-66 224.2 0.0 1.9e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase GN3L_Grn1 PF08701.11 GAX20986.1 - 1.4e-17 63.5 12.6 1.4e-17 63.5 12.6 1.9 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 GAX20986.1 - 1.6e-16 60.4 0.1 3.4e-13 49.7 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX20986.1 - 6.6e-07 29.0 0.1 2.4e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX20986.1 - 0.0026 17.7 3.3 0.36 10.7 0.1 2.7 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 GAX20986.1 - 0.036 13.6 2.1 0.37 10.3 0.0 3.2 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 GAX20986.1 - 0.049 14.2 0.0 0.18 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain LcrG PF07216.12 GAX20986.1 - 0.53 10.2 8.7 0.073 13.0 3.1 2.4 2 0 0 2 2 2 0 LcrG protein MeaB PF03308.16 GAX20986.1 - 0.75 8.7 3.9 0.24 10.4 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4670 PF15709.5 GAX20986.1 - 1.5 8.1 23.2 2 7.6 23.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Dynamin_N PF00350.23 GAX20986.1 - 2.2 8.3 7.8 0.97 9.5 0.1 3.5 2 2 1 3 3 3 0 Dynamin family SET PF00856.28 GAX20987.1 - 1.5e-18 67.8 0.3 7.2e-18 65.5 0.3 2.2 1 1 0 1 1 1 1 SET domain Las1 PF04031.13 GAX20988.1 - 4e-37 127.7 1.6 4e-37 127.7 1.6 1.8 2 0 0 2 2 2 1 Las1-like DnaJ PF00226.31 GAX20989.1 - 1.9e-27 95.2 3.8 3e-27 94.5 3.8 1.3 1 0 0 1 1 1 1 DnaJ domain Cadherin-like PF12733.7 GAX20989.1 - 0.061 13.9 0.0 0.33 11.5 0.0 2.1 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain EF_TS PF00889.19 GAX20990.1 - 0.031 13.9 0.1 0.057 13.0 0.1 1.5 1 0 0 1 1 1 0 Elongation factor TS Hist_deacetyl PF00850.19 GAX20991.1 - 1.3e-27 97.1 0.0 1.7e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF1840 PF08895.11 GAX20991.1 - 0.14 12.5 1.2 0.61 10.5 2.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PRA1 PF03208.19 GAX20994.1 - 1.2e-14 54.2 10.0 3e-14 52.9 10.0 1.6 1 1 0 1 1 1 1 PRA1 family protein Phage_holin_3_6 PF07332.11 GAX20994.1 - 0.034 14.2 7.7 0.25 11.4 7.7 2.1 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Hydrolase_4 PF12146.8 GAX20996.1 - 5.4e-11 42.2 0.1 5.8e-05 22.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX20996.1 - 5e-08 32.9 0.2 0.005 16.5 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX20996.1 - 6.7e-07 29.0 0.0 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAX20996.1 - 0.00011 22.1 0.0 0.00096 19.0 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 GAX20996.1 - 0.0067 16.1 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 GAX20996.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_3 PF07859.13 GAX20996.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 GAX20996.1 - 0.029 13.9 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 GAX20996.1 - 0.038 13.8 0.0 0.12 12.1 0.0 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase family LIP PF03583.14 GAX20996.1 - 0.053 12.8 0.1 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase DUF1749 PF08538.10 GAX20996.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) ADK PF00406.22 GAX20997.1 - 6.1e-45 153.0 0.0 8e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX20997.1 - 5.5e-21 75.4 0.0 1.2e-20 74.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 GAX20997.1 - 6.4e-15 54.9 0.0 1.1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAX20997.1 - 2.1e-06 28.3 0.0 4.3e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX20997.1 - 0.0032 17.7 0.0 0.0079 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX20997.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAX20997.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 GAX20997.1 - 0.037 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 GAX20997.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_10 PF12846.7 GAX20997.1 - 0.13 11.2 0.0 0.55 9.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.21 GAX20997.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PCI PF01399.27 GAX20998.1 - 1.8e-14 54.1 0.2 3.9e-14 53.0 0.2 1.6 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 GAX20998.1 - 0.016 15.2 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family PX PF00787.24 GAX20999.1 - 0.00051 20.0 0.0 0.008 16.2 0.0 2.4 1 1 0 1 1 1 1 PX domain PTS_IIA PF02255.16 GAX20999.1 - 0.81 9.8 4.6 2.4 8.3 4.6 1.8 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit bHLH-MYC_N PF14215.6 GAX21000.1 - 0.00072 19.9 0.1 0.0039 17.5 0.0 2.1 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal CxC6 PF18721.1 GAX21000.1 - 1 9.7 44.8 0.36 11.1 4.4 5.9 2 1 4 6 6 6 0 CxC6 like cysteine cluster associated with KDZ transposases DEAD PF00270.29 GAX21001.1 - 1.8e-20 73.5 0.0 3.4e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 GAX21001.1 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 GAX21001.1 - 1.5e-16 60.7 0.0 5.2e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAX21001.1 - 2.1e-14 54.0 7.3 8.6e-14 52.0 7.3 2.2 1 0 0 1 1 1 1 RecQ zinc-binding zf-GRF PF06839.12 GAX21001.1 - 1.5e-13 50.6 1.4 3.6e-13 49.4 1.4 1.7 1 0 0 1 1 1 1 GRF zinc finger HRDC PF00570.23 GAX21001.1 - 4.9e-10 39.3 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 GAX21001.1 - 0.00017 21.7 0.0 0.00064 19.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 GAX21002.1 - 5.6e-70 235.7 0.0 8e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21002.1 - 2e-36 125.6 0.1 3.3e-36 124.9 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX21002.1 - 0.00022 20.3 0.3 0.00034 19.7 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAX21002.1 - 0.0046 16.3 0.1 0.0071 15.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LTXXQ PF07813.12 GAX21002.1 - 0.046 14.5 0.0 0.084 13.6 0.0 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein FTA2 PF13095.6 GAX21002.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAX21002.1 - 0.14 11.4 0.1 1.2 8.4 0.0 2.2 2 1 1 3 3 3 0 Kinase-like GlcNAc PF11397.8 GAX21004.1 - 3e-71 240.7 0.0 8.2e-70 236.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) RabGAP-TBC PF00566.18 GAX21005.1 - 0.0052 16.5 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 GAX21005.1 - 0.007 16.9 0.0 0.038 14.5 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain Activator-TraM PF11657.8 GAX21005.1 - 0.095 12.5 3.6 9.5 6.1 0.1 2.8 2 0 0 2 2 2 0 Transcriptional activator TraM Wound_ind PF08186.11 GAX21005.1 - 0.14 12.6 1.1 0.33 11.4 0.2 2.1 2 0 0 2 2 2 0 Wound-inducible basic protein family Pinin_SDK_memA PF04696.13 GAX21005.1 - 7.9 6.5 9.7 3.8 7.6 2.8 2.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Josephin PF02099.17 GAX21006.1 - 6.5e-40 136.9 0.4 2.3e-39 135.1 0.1 1.8 2 0 0 2 2 2 1 Josephin UBX PF00789.20 GAX21006.1 - 6.1e-13 48.8 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 GAX21006.1 - 0.085 12.8 1.3 0.71 9.9 1.3 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif MTHFR PF02219.17 GAX21007.1 - 2.6e-92 309.2 0.0 4.2e-92 308.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Zeta_toxin PF06414.12 GAX21008.1 - 2e-21 76.2 0.0 3.9e-09 36.1 0.0 2.9 2 1 1 3 3 3 2 Zeta toxin AAA_33 PF13671.6 GAX21008.1 - 0.0012 19.0 0.0 0.024 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Microtub_bd PF16796.5 GAX21008.1 - 0.016 15.2 0.0 0.052 13.5 0.0 1.9 1 0 0 1 1 1 0 Microtubule binding Kinesin PF00225.23 GAX21008.1 - 0.038 12.9 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain AAA_18 PF13238.6 GAX21008.1 - 0.074 13.6 0.0 0.23 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Tsg PF04668.12 GAX21008.1 - 0.14 12.8 0.1 0.49 11.1 0.0 1.9 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region CactinC_cactus PF09732.9 GAX21009.1 - 2.2e-57 192.4 9.0 4.6e-57 191.4 9.0 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 GAX21009.1 - 4.1e-45 153.9 9.5 4.1e-45 153.9 9.5 1.9 2 0 0 2 2 2 1 Conserved mid region of cactin DUF4692 PF15763.5 GAX21009.1 - 0.032 14.7 7.9 0.073 13.5 7.9 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) eIF-1a PF01176.19 GAX21010.1 - 7.1e-12 45.0 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Prefoldin PF02996.17 GAX21011.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit COPI_assoc PF08507.10 GAX21013.1 - 0.068 13.2 0.4 0.068 13.2 0.4 2.7 2 1 0 2 2 2 0 COPI associated protein HupE_UreJ_2 PF13795.6 GAX21013.1 - 0.72 9.5 12.1 0.14 11.8 2.5 2.9 2 1 1 3 3 3 0 HupE / UreJ protein MerE PF05052.12 GAX21013.1 - 0.77 9.7 7.5 0.081 12.9 1.8 2.2 2 1 0 2 2 2 0 MerE protein JmjC PF02373.22 GAX21014.1 - 2.4e-20 73.1 0.2 2.4e-20 73.1 0.2 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GAX21014.1 - 7.2e-18 65.2 0.1 1.5e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain His_Phos_1 PF00300.22 GAX21016.1 - 1.7e-34 119.2 0.0 9.5e-32 110.3 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FUN14 PF04930.15 GAX21017.1 - 1.1e-24 86.6 2.3 2.1e-24 85.8 2.3 1.4 1 0 0 1 1 1 1 FUN14 family EF-hand_5 PF13202.6 GAX21017.1 - 0.014 14.9 1.2 0.036 13.6 1.2 1.7 1 0 0 1 1 1 0 EF hand Rad21_Rec8_N PF04825.13 GAX21019.1 - 1.8e-38 131.1 0.0 3.1e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAX21019.1 - 7e-14 50.9 0.0 2.6e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SEP PF08059.13 GAX21020.1 - 1.7e-19 70.1 0.0 3.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 GAX21020.1 - 3e-08 33.8 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain LYTB PF02401.18 GAX21021.1 - 2.3e-76 256.6 0.6 2.9e-76 256.2 0.6 1.1 1 0 0 1 1 1 1 LytB protein DNA_pol3_gamma3 PF12169.8 GAX21021.1 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III HSF_DNA-bind PF00447.17 GAX21022.1 - 1.9e-21 76.4 0.1 3.7e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Pro_isomerase PF00160.21 GAX21023.1 - 4.8e-12 46.4 0.0 6.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aminotran_4 PF01063.19 GAX21024.1 - 2.9e-24 86.2 0.0 6.1e-24 85.1 0.0 1.5 1 1 0 1 1 1 1 Amino-transferase class IV RICTOR_V PF14668.6 GAX21025.1 - 0.0016 18.6 0.5 0.0071 16.6 0.2 2.0 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 HMA PF00403.26 GAX21025.1 - 0.061 13.8 0.6 1.2e+02 3.2 0.0 4.1 4 0 0 4 4 4 0 Heavy-metal-associated domain CBS PF00571.28 GAX21026.1 - 1.3e-25 89.6 0.0 2.7e-08 34.1 0.0 4.3 4 0 0 4 4 4 4 CBS domain Hpt PF01627.23 GAX21027.1 - 1.6e-08 34.7 1.2 2.3e-08 34.2 1.2 1.3 1 0 0 1 1 1 1 Hpt domain HSCB_C PF07743.13 GAX21027.1 - 0.009 16.5 2.4 0.0091 16.5 0.5 1.9 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain CALM_bind PF16025.5 GAX21027.1 - 0.061 13.8 0.5 0.098 13.1 0.5 1.3 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding INT_SG_DDX_CT_C PF15300.6 GAX21027.1 - 0.073 12.9 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus TPR_21 PF09976.9 GAX21027.1 - 0.081 12.6 2.0 0.11 12.2 1.7 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain tRNA-synt_1 PF00133.22 GAX21028.1 - 5.6e-37 127.3 0.0 1.9e-24 85.9 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAX21028.1 - 1.2e-17 63.8 0.2 1.2e-07 30.8 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAX21028.1 - 4.9e-14 52.5 0.2 1.1e-13 51.4 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GAX21028.1 - 1.8e-05 24.3 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain TPR_1 PF00515.28 GAX21029.1 - 1.1e-33 113.6 9.7 7.9e-06 25.5 0.2 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21029.1 - 3e-32 108.1 9.8 1.1e-05 25.2 0.3 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAX21029.1 - 8e-20 70.3 8.9 0.0041 16.8 0.0 6.4 4 2 2 6 6 6 5 TPR repeat TPR_8 PF13181.6 GAX21029.1 - 5.5e-15 54.3 11.7 0.01 16.0 0.1 7.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX21029.1 - 4.9e-14 51.2 2.0 0.0035 17.2 0.0 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX21029.1 - 4.3e-13 49.7 5.9 0.036 14.7 0.3 5.2 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21029.1 - 5.8e-12 45.7 9.1 0.004 17.4 0.4 4.9 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAX21029.1 - 1.7e-10 41.2 7.3 0.0024 18.3 0.0 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX21029.1 - 2.8e-09 37.0 4.9 0.00065 20.2 0.2 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX21029.1 - 4.2e-08 33.0 11.3 0.73 10.4 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_3 PF07720.12 GAX21029.1 - 2.2e-07 30.7 4.4 0.022 14.7 0.2 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX21029.1 - 1.3e-06 28.5 0.8 0.023 14.8 0.1 3.8 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX21029.1 - 1.8e-06 28.3 0.2 6.7 7.8 0.2 5.5 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX21029.1 - 0.00014 21.6 7.4 1.7 8.6 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX21029.1 - 0.015 15.4 1.6 4.1 7.6 0.4 3.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 GAX21029.1 - 0.017 14.6 2.9 3.8 7.0 0.0 4.2 5 0 0 5 5 5 0 SHNi-TPR DUF3856 PF12968.7 GAX21029.1 - 0.025 14.7 2.3 1.5 8.9 0.1 3.5 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 GAX21029.1 - 0.051 13.7 14.5 5.5 7.1 0.4 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Membralin PF09746.9 GAX21029.1 - 0.17 10.9 0.5 0.37 9.8 0.5 1.5 1 0 0 1 1 1 0 Tumour-associated protein DUF5113 PF17140.4 GAX21029.1 - 1.1 9.0 7.3 2.8 7.7 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) MAS20 PF02064.15 GAX21029.1 - 1.1 9.3 7.8 68 3.6 4.0 3.6 3 1 0 3 3 3 0 MAS20 protein import receptor ANAPC3 PF12895.7 GAX21029.1 - 3.7 7.8 9.8 1.6 9.0 0.3 3.8 2 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 GAX21029.1 - 4.8 7.6 7.7 9.8 6.6 0.2 3.6 4 0 0 4 4 4 0 Bacterial transcriptional activator domain OCD_Mu_crystall PF02423.15 GAX21031.1 - 7.4e-49 166.4 0.1 9.9e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 GAX21031.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_2 PF12796.7 GAX21032.1 - 5.3e-13 49.4 0.0 4.3e-05 24.0 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX21032.1 - 9.3e-10 37.9 1.7 0.022 15.2 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 GAX21032.1 - 3.1e-07 30.6 0.6 0.0029 17.9 0.1 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX21032.1 - 7.2e-06 26.2 3.9 0.44 11.1 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 GAX21032.1 - 9e-06 26.1 0.6 0.42 11.3 0.1 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) MOR2-PAG1_C PF14225.6 GAX21032.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Cell morphogenesis C-terminal Linker_histone PF00538.19 GAX21033.1 - 2.8e-17 62.8 2.5 2.8e-17 62.8 2.5 2.4 1 1 1 2 2 2 1 linker histone H1 and H5 family DUF356 PF04009.12 GAX21033.1 - 0.019 15.2 0.8 0.019 15.2 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF356) Ndc1_Nup PF09531.10 GAX21033.1 - 8.9 4.9 15.5 9.8 4.7 15.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAE2 PF08573.10 GAX21035.1 - 0.0023 19.0 1.0 0.0023 19.0 1.0 3.8 2 2 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus KilA-N PF04383.13 GAX21035.1 - 0.041 13.7 0.4 8.6 6.3 0.0 2.4 2 0 0 2 2 2 0 KilA-N domain zf-RanBP PF00641.18 GAX21036.1 - 0.00031 20.0 1.7 0.00063 19.0 1.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UPF0242 PF06785.11 GAX21036.1 - 0.052 13.6 3.1 0.083 13.0 3.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 GAX21036.1 - 0.072 13.7 0.3 0.16 12.6 0.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Sec10 PF07393.11 GAX21037.1 - 1.8e-19 69.7 0.0 4.7e-10 38.6 0.0 2.4 2 1 0 2 2 2 2 Exocyst complex component Sec10 RINT1_TIP1 PF04437.13 GAX21037.1 - 0.0064 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF3231 PF11553.8 GAX21037.1 - 0.034 13.8 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) Tricorn_C1 PF14684.6 GAX21037.1 - 0.06 13.4 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Tricorn protease C1 domain DUF1028 PF06267.12 GAX21037.1 - 0.061 13.1 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF1028) TCR PF03638.15 GAX21038.1 - 8.6e-22 77.2 49.5 9.5e-12 45.0 18.6 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.7 GAX21038.1 - 1.7e-05 24.6 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF5582 PF17819.1 GAX21038.1 - 0.021 15.3 0.1 0.021 15.3 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5582) F-box PF00646.33 GAX21038.1 - 0.032 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 F-box domain Orbi_NS1 PF01718.16 GAX21038.1 - 0.26 9.7 3.2 0.36 9.3 3.2 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein MSL2-CXC PF16682.5 GAX21038.1 - 0.61 10.3 37.1 0.82 9.8 14.8 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 EVI2A PF05399.11 GAX21038.1 - 0.62 9.6 6.6 0.18 11.4 0.8 2.5 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Mito_carr PF00153.27 GAX21040.1 - 5.4e-68 225.0 4.8 4.4e-24 84.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Polyketide_cyc2 PF10604.9 GAX21041.1 - 0.00033 20.9 0.0 0.00097 19.4 0.0 1.8 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX21041.1 - 0.00052 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport REV PF00424.18 GAX21041.1 - 0.11 12.5 0.6 0.35 10.9 0.6 1.9 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) ABC_tran PF00005.27 GAX21042.1 - 2.7e-44 151.0 5.9 2.8e-22 79.7 0.0 3.6 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 GAX21042.1 - 1.9e-13 50.9 15.4 7.8e-05 22.6 0.0 5.2 3 2 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX21042.1 - 6.6e-11 42.1 5.4 0.011 15.2 0.0 4.3 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX21042.1 - 3.7e-07 29.8 0.2 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX21042.1 - 3.8e-07 30.2 0.0 0.0017 18.3 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAX21042.1 - 5.4e-05 23.6 0.4 0.19 12.1 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 GAX21042.1 - 7.9e-05 23.1 0.1 0.39 11.2 0.1 3.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran_Xtn PF12848.7 GAX21042.1 - 0.00018 21.4 10.0 0.00018 21.4 10.0 6.6 6 1 0 6 6 4 1 ABC transporter RNA_helicase PF00910.22 GAX21042.1 - 0.00021 21.6 0.0 0.42 11.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase MMR_HSR1 PF01926.23 GAX21042.1 - 0.00038 20.5 4.8 0.027 14.5 0.0 4.0 4 1 0 4 4 4 1 50S ribosome-binding GTPase AAA_33 PF13671.6 GAX21042.1 - 0.00059 20.0 0.1 0.21 11.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 GAX21042.1 - 0.00097 19.4 6.4 0.39 11.0 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 GAX21042.1 - 0.0012 19.2 2.6 0.47 10.7 0.0 3.5 4 0 0 4 4 2 1 AAA domain AAA_15 PF13175.6 GAX21042.1 - 0.0015 18.3 0.0 0.011 15.4 0.1 5.7 4 1 2 6 6 5 2 AAA ATPase domain AAA_14 PF13173.6 GAX21042.1 - 0.0015 18.6 0.2 1.6 8.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 GAX21042.1 - 0.0034 17.3 0.1 0.94 9.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 GAX21042.1 - 0.0038 16.8 0.0 0.86 9.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 GAX21042.1 - 0.0058 17.1 2.5 0.0058 17.1 2.5 6.3 6 2 0 6 6 5 2 AAA domain AAA_5 PF07728.14 GAX21042.1 - 0.011 15.7 1.4 1 9.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX21042.1 - 0.024 14.0 0.1 15 4.9 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GAX21042.1 - 0.043 13.5 9.2 0.47 10.1 0.1 3.8 3 1 0 3 3 2 0 AAA domain ATPase PF06745.13 GAX21042.1 - 0.05 13.0 1.0 2.2 7.6 0.0 3.1 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.6 GAX21042.1 - 0.18 12.4 8.8 0.37 11.3 0.0 4.3 4 0 0 4 4 3 0 AAA domain Dynamin_N PF00350.23 GAX21042.1 - 0.93 9.5 0.0 0.93 9.5 0.0 4.9 4 1 0 4 4 4 0 Dynamin family DUF1281 PF06924.11 GAX21043.1 - 0.0037 16.8 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1281) tRNA-synt_1b PF00579.25 GAX21044.1 - 1.6e-79 267.3 0.0 2e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TPR_12 PF13424.6 GAX21046.1 - 3.1e-30 104.3 1.7 2.6e-11 43.7 0.2 4.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX21046.1 - 2.4e-27 94.0 1.1 1.2e-05 25.0 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21046.1 - 7.9e-22 75.6 1.0 0.0036 17.3 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX21046.1 - 9.2e-19 66.4 2.8 0.0016 18.2 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX21046.1 - 6.3e-10 38.5 10.5 0.068 13.4 0.0 5.7 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX21046.1 - 2.8e-09 37.0 4.5 0.77 10.7 0.1 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX21046.1 - 3.3e-07 30.8 2.6 0.34 11.6 0.3 5.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX21046.1 - 2.3e-06 27.2 3.2 0.012 15.5 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX21046.1 - 3.4e-06 26.4 1.0 0.028 13.9 0.0 3.8 4 0 0 4 4 4 1 SHNi-TPR TPR_19 PF14559.6 GAX21046.1 - 1.6e-05 25.3 3.3 0.53 10.8 0.1 4.6 3 2 1 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX21046.1 - 3e-05 24.0 0.5 0.67 10.1 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 GAX21046.1 - 6.8e-05 23.3 1.1 21 6.0 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX21046.1 - 7.4e-05 22.3 0.0 0.0027 17.2 0.0 2.3 2 0 0 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 GAX21046.1 - 0.00039 20.0 1.1 5 6.9 0.0 5.6 6 0 0 6 6 6 1 TPR repeat Coatomer_E PF04733.14 GAX21046.1 - 0.087 12.2 3.7 6.3 6.1 0.1 4.3 2 2 1 4 4 4 0 Coatomer epsilon subunit TPR_9 PF13371.6 GAX21046.1 - 0.84 9.8 2.8 3.2 8.0 0.6 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat CLP1_P PF16575.5 GAX21047.1 - 8.8e-46 156.1 0.0 2e-45 154.9 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 GAX21047.1 - 3.4e-24 85.5 0.1 5.8e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 GAX21047.1 - 1.8e-20 73.0 0.0 3.2e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 GAX21047.1 - 0.00088 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 GAX21047.1 - 0.0027 18.1 0.0 0.0062 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.7 GAX21047.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_35 PF14516.6 GAX21047.1 - 0.034 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.18 GAX21047.1 - 0.039 13.3 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 GAX21047.1 - 0.042 13.4 0.2 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 GAX21047.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAX21047.1 - 0.066 13.3 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase CbiA PF01656.23 GAX21047.1 - 0.068 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 GAX21047.1 - 0.09 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX21047.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Rpn9_C PF18261.1 GAX21047.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix DEAD PF00270.29 GAX21048.1 - 1.6e-23 83.4 0.0 3.4e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX21048.1 - 5.6e-05 23.5 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX21048.1 - 0.00059 19.9 0.0 0.0018 18.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SAP PF02037.27 GAX21048.1 - 0.0082 15.9 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 SAP domain AAA_19 PF13245.6 GAX21048.1 - 0.017 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cation_efflux PF01545.21 GAX21050.1 - 3e-28 98.9 7.5 3.7e-28 98.6 7.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAX21050.1 - 1.4e-09 38.0 0.1 3.2e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Chordopox_A13L PF05961.11 GAX21050.1 - 0.0019 18.4 0.0 0.054 13.7 0.0 2.4 2 0 0 2 2 2 1 Chordopoxvirus A13L protein DUF386 PF04074.12 GAX21050.1 - 0.084 12.8 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 YhcH/YjgK/YiaL MAPEG PF01124.18 GAX21050.1 - 0.12 12.3 0.9 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 MAPEG family PfkB PF00294.24 GAX21051.1 - 3e-47 161.4 6.1 9.5e-47 159.8 6.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GAX21051.1 - 1.2e-07 31.4 0.0 3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ABC1 PF03109.16 GAX21052.1 - 5.4e-30 104.0 0.0 1.2e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX21052.1 - 9.6e-05 22.4 1.0 0.001 19.1 0.5 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX21052.1 - 0.0059 16.0 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Mannosyl_trans2 PF04188.13 GAX21053.1 - 7.7e-37 127.6 22.1 2.1e-35 122.9 22.1 2.6 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Choline_transpo PF04515.12 GAX21054.1 - 2.1e-60 204.6 13.7 2.1e-60 204.6 13.7 2.3 1 1 1 2 2 2 1 Plasma-membrane choline transporter Pox_P21 PF05313.12 GAX21054.1 - 0.1 12.1 3.1 0.37 10.3 3.1 1.9 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Isy1 PF06246.12 GAX21055.1 - 2.9e-72 243.3 6.4 5e-71 239.3 6.4 1.9 1 1 0 1 1 1 1 Isy1-like splicing family DUF1751 PF08551.10 GAX21056.1 - 8.5e-07 29.5 3.3 1.9e-06 28.3 3.3 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 GAX21056.1 - 3.5e-05 23.8 8.7 6.5e-05 23.0 8.7 1.4 1 0 0 1 1 1 1 Rhomboid family SET PF00856.28 GAX21057.1 - 3.2e-20 73.2 4.1 4.1e-20 72.9 0.5 2.9 3 0 0 3 3 3 1 SET domain N-SET PF11764.8 GAX21057.1 - 2 8.5 7.9 0.17 12.0 2.1 2.0 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N DEAD PF00270.29 GAX21058.1 - 1.1e-47 162.1 0.0 8.1e-47 159.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX21058.1 - 3e-25 88.7 0.0 8.4e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAX21058.1 - 0.00012 21.4 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAX21058.1 - 0.0071 16.4 0.0 0.028 14.4 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 GAX21058.1 - 0.043 13.1 0.0 0.2 11.0 0.0 2.1 2 1 0 2 2 2 0 SecA DEAD-like domain C1_1 PF00130.22 GAX21059.1 - 3.3e-05 23.7 9.0 6.1e-05 22.8 9.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) But2 PF09792.9 GAX21059.1 - 0.012 16.0 2.9 0.29 11.5 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin 3 binding protein But2 C-terminal domain Reticulon PF02453.17 GAX21059.1 - 0.13 12.2 2.1 11 5.9 0.1 2.3 2 0 0 2 2 2 0 Reticulon Brr6_like_C_C PF10104.9 GAX21059.1 - 0.23 11.2 4.5 0.33 10.7 0.3 2.4 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain C1_2 PF03107.16 GAX21059.1 - 2.2 8.7 8.6 4.8 7.6 8.6 1.6 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 GAX21059.1 - 7.8 6.7 11.1 18 5.6 11.1 1.5 1 0 0 1 1 1 0 B-box zinc finger FAD_binding_8 PF08022.12 GAX21060.1 - 1.2e-11 44.7 0.0 4.5e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 GAX21060.1 - 2.9e-08 34.0 0.1 0.0037 17.4 0.1 2.6 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAX21060.1 - 1.3e-06 28.5 2.6 3.7e-06 27.1 2.6 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 GAX21060.1 - 0.0057 17.3 0.0 0.44 11.2 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SBP_bac_5 PF00496.22 GAX21061.1 - 3.6e-33 115.1 0.0 1.1e-27 97.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle YrhC PF14143.6 GAX21061.1 - 0.03 14.4 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 YrhC-like protein YajC PF02699.15 GAX21061.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit ABC_membrane PF00664.23 GAX21062.1 - 1.7e-59 201.8 22.1 4.7e-30 105.2 10.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX21062.1 - 4.8e-52 176.1 0.0 1.5e-30 106.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 GAX21062.1 - 4.8e-08 33.1 1.4 0.0053 16.8 0.3 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX21062.1 - 1.6e-07 31.4 1.5 0.00025 21.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAX21062.1 - 1e-06 28.3 0.8 0.027 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 GAX21062.1 - 2.9e-06 26.9 6.9 0.095 12.1 0.5 4.1 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 GAX21062.1 - 1.1e-05 25.6 3.9 0.001 19.1 1.1 2.7 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 GAX21062.1 - 0.00024 21.3 2.3 0.14 12.2 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_24 PF13479.6 GAX21062.1 - 0.00031 20.5 0.3 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Orai-1 PF07856.12 GAX21062.1 - 0.00038 20.2 0.6 0.11 12.2 0.1 3.1 2 0 0 2 2 2 1 Mediator of CRAC channel activity AAA_16 PF13191.6 GAX21062.1 - 0.00068 20.1 0.5 0.49 10.8 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX21062.1 - 0.00086 19.6 0.5 3.1 8.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAX21062.1 - 0.0014 19.2 2.2 1.4 9.3 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 GAX21062.1 - 0.0025 17.4 0.4 1.9 8.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 GAX21062.1 - 0.0034 17.2 0.1 1.3 8.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAX21062.1 - 0.0049 16.5 1.5 0.83 9.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 GAX21062.1 - 0.0055 16.0 0.7 2.7 7.2 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin cobW PF02492.19 GAX21062.1 - 0.0083 15.7 2.0 0.31 10.6 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 GAX21062.1 - 0.0099 15.0 0.0 3.1 6.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 GAX21062.1 - 0.012 15.4 3.9 0.2 11.3 0.4 3.6 3 1 0 3 3 3 0 AAA domain MeaB PF03308.16 GAX21062.1 - 0.018 14.0 0.8 3.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 GAX21062.1 - 0.025 14.5 0.1 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 GAX21062.1 - 0.035 13.4 4.3 0.076 12.3 0.4 2.5 2 0 0 2 2 2 0 AIG1 family NB-ARC PF00931.22 GAX21062.1 - 0.037 13.2 2.6 2 7.5 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 GAX21062.1 - 0.042 13.2 0.8 7.1 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAX21062.1 - 0.044 14.2 0.6 15 6.1 0.0 3.4 3 0 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.9 GAX21062.1 - 0.055 12.4 1.0 4.1 6.2 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain GTP_EFTU PF00009.27 GAX21062.1 - 0.055 13.0 0.1 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 GAX21062.1 - 0.056 13.2 0.5 4 7.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 GAX21062.1 - 0.079 12.9 0.2 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 GAX21062.1 - 0.085 12.9 0.5 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 GAX21062.1 - 0.12 12.6 1.0 41 4.5 0.0 3.7 4 0 0 4 4 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAX21062.1 - 0.15 12.6 0.3 5.5 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAX21062.1 - 0.17 11.7 0.4 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 GAX21062.1 - 0.19 11.5 1.0 15 5.2 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IIGP PF05049.13 GAX21062.1 - 0.24 10.4 2.1 8.4 5.3 0.2 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 GAX21062.1 - 0.26 11.5 5.0 5.8 7.1 0.1 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 GAX21062.1 - 0.35 10.8 1.3 25 4.8 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 GAX21062.1 - 1.4 8.8 4.8 22 4.9 0.1 3.2 3 0 0 3 3 3 0 NTPase TH1 PF04858.13 GAX21063.1 - 1.7e-45 155.8 0.3 2e-25 89.5 0.1 2.3 2 0 0 2 2 2 2 TH1 protein WW PF00397.26 GAX21063.1 - 5e-21 74.5 13.8 3e-11 43.2 3.7 2.6 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 GAX21063.1 - 0.28 11.5 7.0 4 7.8 2.5 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain PAP_fibrillin PF04755.12 GAX21064.1 - 0.0019 18.2 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin Lipase_3 PF01764.25 GAX21065.1 - 1.2e-21 77.1 0.0 1.9e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Proteasome PF00227.26 GAX21066.1 - 5.4e-49 166.3 0.2 6.2e-49 166.1 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit FaeA PF04703.12 GAX21066.1 - 0.11 12.8 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 FaeA-like protein Ribosomal_L11 PF00298.19 GAX21067.1 - 5.6e-22 78.0 0.0 7.7e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAX21067.1 - 9e-22 76.7 0.0 1.7e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribonuc_P_40 PF08584.11 GAX21068.1 - 0.052 12.8 1.0 0.95 8.7 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit PPR_2 PF13041.6 GAX21069.1 - 3.9e-28 97.4 5.6 0.003 17.7 0.1 8.9 8 1 1 9 9 9 8 PPR repeat family PPR_1 PF12854.7 GAX21069.1 - 7e-26 89.6 2.4 0.00029 20.5 0.0 10.5 11 2 0 11 11 11 6 PPR repeat PPR PF01535.20 GAX21069.1 - 2.9e-17 61.6 10.4 5e-06 26.4 0.0 9.3 10 2 0 10 10 10 4 PPR repeat PPR_3 PF13812.6 GAX21069.1 - 1.3e-16 60.4 0.0 0.0047 17.0 0.0 8.2 2 2 8 10 10 10 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX21069.1 - 8.2e-12 44.9 5.7 3.2e-06 26.7 0.1 4.3 2 1 3 5 5 5 2 Pentacotripeptide-repeat region of PRORP Annexin_like PF18411.1 GAX21069.1 - 0.00015 21.9 0.4 0.1 12.9 0.0 4.2 3 1 2 5 5 5 1 Annexin-like domain Wzy_C_2 PF11846.8 GAX21069.1 - 0.014 15.3 1.5 22 4.9 0.1 4.3 3 1 2 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal LPD11 PF18824.1 GAX21069.1 - 0.061 13.4 0.0 5.4 7.2 0.0 2.8 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 ChaB PF06150.12 GAX21069.1 - 3.1 8.4 7.1 45 4.7 0.1 4.3 5 0 0 5 5 5 0 ChaB Lipase_GDSL_2 PF13472.6 GAX21071.1 - 8.7e-07 29.5 0.0 3e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX21071.1 - 0.004 17.1 0.0 0.02 14.9 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Saf_2TM PF18303.1 GAX21071.1 - 0.068 12.8 0.5 1.7 8.2 0.4 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain eRF1_2 PF03464.15 GAX21072.1 - 5.5e-45 152.9 0.0 8.7e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAX21072.1 - 3.4e-36 124.1 0.2 8e-36 123.0 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 GAX21072.1 - 7e-22 77.8 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 GAX21072.1 - 3.4e-10 40.3 0.0 6.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 GAX21072.1 - 2.2e-07 31.2 0.0 3.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 PTSIIB_sorb PF03830.15 GAX21072.1 - 0.082 13.1 0.6 8.4 6.6 0.1 2.2 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component Gp45_2 PF17470.2 GAX21072.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Phage gene product 45.2 2-Hacid_dh_C PF02826.19 GAX21073.1 - 1.8e-52 177.2 0.0 3.1e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAX21073.1 - 0.00029 20.5 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_10 PF13460.6 GAX21073.1 - 0.031 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_2 PF03446.15 GAX21073.1 - 0.035 14.3 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 GAX21073.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH PF00763.23 GAX21074.1 - 2.7e-22 79.2 0.0 4.5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAX21074.1 - 3.1e-14 52.6 0.3 9e-13 47.8 0.3 2.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 GAX21074.1 - 0.018 14.4 0.0 0.066 12.6 0.0 1.8 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 GAX21075.1 - 1.1e-33 116.3 0.0 1.5e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX21075.1 - 1.4e-18 67.4 0.0 2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX21075.1 - 8.5e-14 51.9 0.0 1.6e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX21075.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PALP PF00291.25 GAX21075.1 - 0.0036 16.8 0.1 0.0055 16.2 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Eno-Rase_NADH_b PF12242.8 GAX21075.1 - 0.0062 16.3 0.2 0.015 15.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 GAX21075.1 - 0.012 15.9 0.6 0.021 15.1 0.6 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GAX21075.1 - 0.013 15.4 0.5 0.023 14.6 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 GAX21075.1 - 0.014 15.4 0.5 0.033 14.2 0.1 1.8 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 GAX21075.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GAX21075.1 - 0.034 14.0 0.3 0.052 13.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAX21075.1 - 0.12 12.7 0.3 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain Tmemb_55A PF09788.9 GAX21076.1 - 0.015 14.4 0.6 0.017 14.2 0.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A MRNIP PF15749.5 GAX21076.1 - 0.026 15.3 1.7 0.026 15.3 1.7 1.8 2 0 0 2 2 2 0 MRN-interacting protein DNA_primase_lrg PF04104.14 GAX21076.1 - 0.049 13.0 0.2 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit zf-CSL PF05207.13 GAX21076.1 - 0.05 13.3 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 CSL zinc finger Ribosomal_S27e PF01667.17 GAX21076.1 - 0.05 13.3 4.2 0.091 12.5 4.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 DUF2614 PF11023.8 GAX21076.1 - 0.07 13.2 0.7 0.094 12.8 0.2 1.5 2 0 0 2 2 2 0 Zinc-ribbon containing domain FANCD2OS PF15124.6 GAX21076.1 - 0.079 13.2 0.3 0.1 12.8 0.3 1.1 1 0 0 1 1 1 0 FANCD2 opposite strand protein C1_1 PF00130.22 GAX21076.1 - 0.17 11.8 1.4 0.31 10.9 1.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Auto_anti-p27 PF06677.12 GAX21076.1 - 0.19 11.9 2.1 0.38 11.0 2.1 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-U1 PF06220.12 GAX21076.1 - 0.36 10.6 0.1 0.36 10.6 0.1 2.9 4 0 0 4 4 4 0 U1 zinc finger RIO1 PF01163.22 GAX21077.1 - 1.4e-40 138.9 0.0 1.7e-30 106.0 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 GAX21077.1 - 1.8e-27 95.4 0.2 5.7e-27 93.8 0.1 2.0 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 GAX21077.1 - 0.0014 18.6 9.0 0.012 15.5 0.3 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 GAX21077.1 - 0.0024 17.2 0.2 0.15 11.4 0.1 2.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_23 PF13489.6 GAX21078.1 - 8e-06 25.8 0.0 2.8e-05 24.0 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX21078.1 - 3.7e-05 24.3 0.0 0.00063 20.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX21078.1 - 0.00016 22.3 0.0 0.00071 20.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX21078.1 - 0.00018 21.3 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAX21078.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 GAX21078.1 - 0.056 14.1 0.0 0.29 11.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain TEX13 PF15186.6 GAX21078.1 - 0.18 11.5 6.4 0.89 9.2 3.1 3.1 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family RRM_1 PF00076.22 GAX21079.1 - 1.1e-34 118.1 0.0 2.7e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX21079.1 - 1.2e-16 60.6 0.2 9.1e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 GAX21079.1 - 0.0029 17.6 0.0 1.4 9.0 0.0 2.5 2 1 0 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 GAX21079.1 - 0.08 13.2 0.1 24 5.1 0.0 3.2 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Laminin_G_1 PF00054.23 GAX21079.1 - 0.093 13.0 0.0 0.93 9.7 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain RRM_5 PF13893.6 GAX21079.1 - 0.14 11.7 0.0 0.44 10.1 0.0 1.7 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 GAX21080.1 - 9.9e-31 106.9 0.0 1.8e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX21080.1 - 2e-07 31.5 0.1 3.9e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX21080.1 - 3.6e-06 27.3 0.1 2.6e-05 24.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX21080.1 - 8.2e-06 25.8 0.8 3e-05 24.0 0.8 1.9 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 GAX21080.1 - 0.00025 21.6 0.0 0.00068 20.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 GAX21080.1 - 0.00048 20.2 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAX21080.1 - 0.00076 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAX21080.1 - 0.0018 17.5 0.0 0.0066 15.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAX21080.1 - 0.0024 18.2 0.0 0.0055 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 GAX21080.1 - 0.0026 17.6 0.0 0.0082 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAX21080.1 - 0.0033 17.2 0.0 0.03 14.1 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAX21080.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 GAX21080.1 - 0.0059 16.8 0.0 0.0095 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAX21080.1 - 0.0084 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 GAX21080.1 - 0.0089 15.8 0.1 0.023 14.4 0.1 1.9 1 1 0 1 1 1 1 Cytidylate kinase TsaE PF02367.17 GAX21080.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 GAX21080.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 GAX21080.1 - 0.02 14.6 0.0 0.052 13.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX21080.1 - 0.026 14.1 0.1 0.14 11.7 0.0 1.9 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAX21080.1 - 0.028 13.8 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAX21080.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 GAX21080.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 GAX21080.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 GAX21080.1 - 0.071 13.4 0.0 0.2 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 GAX21080.1 - 0.095 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 GAX21080.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 GAX21080.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_13 PF13166.6 GAX21080.1 - 0.18 10.4 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Antimicrobial_7 PF08102.11 GAX21081.1 - 0.019 15.2 0.0 6.5 7.1 0.0 3.3 3 0 0 3 3 3 0 Scorpion antimicrobial peptide DUF5500 PF17604.2 GAX21081.1 - 2.4 8.3 10.4 21 5.3 0.1 4.6 3 1 3 6 6 6 0 Family of unknown function (DUF5500) MIR PF02815.19 GAX21082.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 MIR domain zf-HIT PF04438.16 GAX21084.1 - 1.7e-07 31.0 12.3 3.4e-07 30.0 12.3 1.5 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 GAX21084.1 - 0.077 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 GAX21084.1 - 0.1 12.7 11.2 0.28 11.3 11.2 1.9 1 0 0 1 1 1 0 MYND finger Radical_SAM PF04055.21 GAX21085.1 - 6.4e-16 59.2 0.0 9.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 GAX21085.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Chloroa_b-bind PF00504.21 GAX21087.1 - 7e-34 117.7 0.0 9.3e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TLC PF03219.14 GAX21088.1 - 1.4e-05 24.1 8.1 3.2e-05 22.8 0.1 3.0 1 1 1 2 2 2 1 TLC ATP/ADP transporter ATP-synt PF00231.19 GAX21089.1 - 7.7e-74 248.9 0.9 8.7e-74 248.7 0.9 1.0 1 0 0 1 1 1 1 ATP synthase Spt5_N PF11942.8 GAX21089.1 - 0.12 13.4 0.1 0.25 12.4 0.1 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ras PF00071.22 GAX21089.1 - 0.24 11.0 2.8 0.55 9.8 0.8 2.1 1 1 1 2 2 2 0 Ras family PUF PF00806.19 GAX21091.1 - 5.4e-07 28.9 0.1 0.036 13.8 0.0 4.7 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat CPL PF08144.11 GAX21091.1 - 2e-06 28.2 2.5 0.00019 21.8 0.0 3.7 2 2 2 4 4 4 1 CPL (NUC119) domain DXP_synthase_N PF13292.6 GAX21091.1 - 0.051 12.8 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase AIM5 PF17050.5 GAX21091.1 - 4.5 8.2 5.6 12 6.7 1.1 3.2 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 PhoD PF09423.10 GAX21092.1 - 1.4e-14 53.9 0.0 1.2e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase 2OG-FeII_Oxy_2 PF13532.6 GAX21093.1 - 3.6e-13 50.1 0.0 4.8e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_S2 PF00318.20 GAX21094.1 - 1.3e-26 93.2 0.2 2.3e-14 53.1 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 TFIID_20kDa PF03847.13 GAX21095.1 - 1.2e-13 51.4 0.0 1.8e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 GAX21095.1 - 0.042 13.9 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Ribosomal_S24e PF01282.19 GAX21096.1 - 3.9e-32 110.0 0.0 7.2e-32 109.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Fes1 PF08609.10 GAX21097.1 - 1.3e-05 26.0 1.2 0.0022 18.8 0.2 2.5 2 0 0 2 2 2 2 Nucleotide exchange factor Fes1 RasGAP_C PF03836.15 GAX21097.1 - 0.035 14.3 1.0 0.08 13.1 1.0 1.5 1 0 0 1 1 1 0 RasGAP C-terminus Atx10homo_assoc PF09759.9 GAX21097.1 - 0.063 13.3 0.0 0.88 9.6 0.0 2.7 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain AAA_lid_7 PF17867.1 GAX21097.1 - 0.1 12.8 0.4 18 5.6 0.1 2.8 1 1 1 2 2 2 0 Midasin AAA lid domain TPR_1 PF00515.28 GAX21098.1 - 2.3e-09 36.7 8.2 0.019 14.7 0.0 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21098.1 - 9.3e-07 29.1 18.4 0.057 13.7 2.6 5.2 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21098.1 - 5.9e-06 26.0 9.2 2.5 8.4 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX21098.1 - 6.1e-05 22.6 4.1 1.5 8.6 0.0 3.9 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 GAX21098.1 - 0.0009 19.3 11.5 2.8 8.4 0.0 5.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 GAX21098.1 - 0.026 14.3 6.3 1.7 8.3 0.5 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain SNAP PF14938.6 GAX21098.1 - 0.075 12.4 6.9 0.83 9.0 3.9 2.5 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 GAX21098.1 - 0.12 13.1 0.2 0.12 13.1 0.2 4.5 4 2 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX21098.1 - 0.18 11.9 16.4 9.7 6.5 0.1 6.5 5 2 2 7 7 7 0 Tetratricopeptide repeat DUF148 PF02520.17 GAX21098.1 - 0.18 11.9 3.0 0.41 10.8 1.3 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF148 TPR_14 PF13428.6 GAX21098.1 - 0.24 12.3 22.3 12 7.1 0.6 6.8 3 2 4 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX21098.1 - 0.53 10.8 20.6 4.6 7.8 1.0 5.0 3 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 GAX21098.1 - 2.1 8.5 12.2 1.3 9.1 0.3 5.4 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain AATF-Che1 PF13339.6 GAX21098.1 - 4.7 7.9 8.0 0.57 10.9 0.4 3.0 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor DUF536 PF04394.14 GAX21098.1 - 9.4 6.2 13.6 0.4 10.6 6.7 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF536 YebG PF07130.12 GAX21099.1 - 0.012 15.5 2.4 0.17 11.8 0.1 2.6 2 0 0 2 2 2 0 YebG protein PhyH PF05721.13 GAX21100.1 - 1.7e-15 57.9 0.0 3.2e-15 57.0 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SET PF00856.28 GAX21101.1 - 0.00089 19.7 0.0 0.0026 18.2 0.0 1.7 1 1 0 1 1 1 1 SET domain Peptidase_S41 PF03572.18 GAX21102.1 - 5.7e-35 120.3 0.0 2.4e-34 118.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GAX21102.1 - 1e-08 34.9 0.1 2.6e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX21102.1 - 4.6e-05 23.7 0.1 0.00016 22.0 0.1 1.9 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX21102.1 - 0.0001 22.6 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Mito_carr PF00153.27 GAX21103.1 - 1.3e-44 150.0 2.6 2.9e-19 68.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1275 PF06912.11 GAX21103.1 - 0.07 13.0 0.4 0.23 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) Spexin PF15171.6 GAX21104.1 - 0.0082 16.3 3.8 1.2 9.4 0.2 3.1 3 0 0 3 3 3 2 Neuropeptide secretory protein family, NPQ, spexin ATC_hydrolase PF14196.6 GAX21104.1 - 0.019 15.7 0.5 1.7 9.4 0.6 2.6 2 1 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase TPR_1 PF00515.28 GAX21104.1 - 0.032 14.1 7.3 1 9.3 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4131 PF13567.6 GAX21104.1 - 0.056 13.1 0.3 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) GalBD_like PF17974.1 GAX21104.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Galactose-binding domain-like TPR_2 PF07719.17 GAX21104.1 - 0.58 10.4 14.1 7.5 6.9 1.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Rhamno_transf PF11316.8 GAX21105.1 - 2.4e-05 23.9 1.4 0.00042 19.8 0.1 2.2 1 1 1 2 2 2 2 Putative rhamnosyl transferase LRR_6 PF13516.6 GAX21107.1 - 0.013 15.5 11.1 0.16 12.1 0.2 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 GAX21107.1 - 0.025 15.0 0.7 1.5 9.3 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Ribosomal_S16 PF00886.19 GAX21108.1 - 1.6e-24 85.7 0.0 2.3e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 CTP_transf_like PF01467.26 GAX21109.1 - 8.7e-17 61.7 0.0 1.6e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Herpes_U15 PF05613.11 GAX21109.1 - 0.065 13.9 0.1 0.16 12.7 0.1 1.6 1 0 0 1 1 1 0 Human herpesvirus U15 protein ATXN-1_C PF12547.8 GAX21109.1 - 0.088 13.2 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator CDP-OH_P_transf PF01066.21 GAX21109.1 - 0.11 13.3 0.4 0.11 13.3 0.4 2.9 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase Metallophos PF00149.28 GAX21110.1 - 1e-06 29.4 0.6 2.1e-06 28.4 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase B PF02216.16 GAX21110.1 - 0.019 15.0 0.1 0.34 10.9 0.1 2.3 2 0 0 2 2 2 0 B domain IMS PF00817.20 GAX21111.1 - 1.6e-39 135.3 0.1 4.7e-39 133.8 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 GAX21111.1 - 2.6e-12 47.5 0.0 8.4e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 GAX21111.1 - 8.3e-10 38.9 0.0 2.1e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAX21111.1 - 2.4e-07 31.1 0.0 6.3e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAX21111.1 - 3.2e-07 30.2 0.0 6.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 GAX21111.1 - 2.8e-05 24.3 0.0 7.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 GAX21111.1 - 0.00044 20.4 0.3 0.0034 17.6 0.1 2.6 2 0 0 2 2 2 1 IMS family HHH motif FMN_dh PF01070.18 GAX21111.1 - 0.053 12.5 0.2 0.15 11.1 0.1 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Mito_carr PF00153.27 GAX21112.1 - 6.5e-61 202.3 1.0 2.9e-22 78.4 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX21112.1 - 0.063 12.4 0.0 0.2 10.8 0.0 1.8 1 0 0 1 1 1 0 Gammaproteobacterial serine protease TPR_1 PF00515.28 GAX21113.1 - 3.9e-19 67.6 6.5 3.8e-05 23.3 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21113.1 - 1.7e-16 58.9 13.3 0.00019 21.3 0.2 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX21113.1 - 1.8e-15 55.7 4.4 0.0001 22.2 0.2 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX21113.1 - 3.7e-13 49.1 13.1 8.6e-05 23.0 0.0 6.7 3 1 3 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAX21113.1 - 5.4e-12 46.1 8.7 2.9e-06 27.8 0.0 5.5 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX21113.1 - 9e-12 45.3 3.8 0.00058 20.3 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX21113.1 - 7.7e-10 38.1 7.5 0.0045 16.9 0.0 6.4 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX21113.1 - 3.7e-09 36.7 2.6 0.00071 19.7 0.1 4.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAX21113.1 - 2.1e-08 33.7 0.8 4.6e-05 23.0 0.0 4.3 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.6 GAX21113.1 - 6.9e-07 29.3 5.9 8e-06 25.9 0.1 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21113.1 - 3e-06 27.4 10.7 0.0055 17.0 0.1 6.3 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX21113.1 - 6.1e-06 26.3 1.9 1.3 9.6 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX21113.1 - 0.00011 22.7 5.9 0.27 11.9 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat RPN7 PF10602.9 GAX21113.1 - 0.04 13.6 0.8 2 8.1 0.2 3.4 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Clathrin PF00637.20 GAX21113.1 - 0.056 13.3 0.3 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_20 PF14561.6 GAX21113.1 - 0.056 13.8 0.1 0.056 13.8 0.1 3.0 4 0 0 4 4 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX21113.1 - 0.064 13.3 1.3 0.99 9.5 0.1 3.0 2 1 1 3 3 2 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 GAX21113.1 - 0.096 12.6 4.5 2.4 8.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 GAX21113.1 - 3.7 8.7 6.3 1.1e+02 4.4 0.6 5.0 5 0 0 5 5 3 0 Aromatic-di-Alanine (AdAR) repeat Spermine_synth PF01564.17 GAX21114.1 - 5.5e-15 55.3 0.1 2e-14 53.4 0.1 2.0 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 GAX21114.1 - 1.3e-08 35.0 2.2 5.9e-07 29.7 0.2 2.9 3 0 0 3 3 3 1 S-adenosylmethionine decarboxylase SET PF00856.28 GAX21114.1 - 4.5e-08 33.7 0.0 2e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 SET domain Apc13p PF05839.11 GAX21115.1 - 0.028 14.6 1.0 0.076 13.2 0.9 1.8 1 1 0 1 1 1 0 Apc13p protein Aldo_ket_red PF00248.21 GAX21116.1 - 5.6e-20 71.7 0.0 4.4e-18 65.5 0.0 2.8 1 1 0 1 1 1 1 Aldo/keto reductase family Ham1p_like PF01725.16 GAX21118.1 - 6.4e-53 179.5 0.0 7.7e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Ham1 family DUF4827 PF16109.5 GAX21118.1 - 0.14 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) MARVEL PF01284.23 GAX21119.1 - 0.011 15.7 0.3 0.021 14.9 0.3 1.4 1 0 0 1 1 1 0 Membrane-associating domain Chloroa_b-bind PF00504.21 GAX21120.1 - 7.9e-32 111.0 0.0 1e-31 110.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Lipase_GDSL_2 PF13472.6 GAX21121.1 - 0.001 19.5 0.0 2.2 8.6 0.0 2.8 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family SpoIISA_toxin PF14171.6 GAX21121.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system ubiquitin PF00240.23 GAX21122.1 - 6.3e-34 115.6 0.9 1.2e-33 114.7 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 GAX21122.1 - 3.4e-19 68.7 1.8 3.4e-19 68.7 1.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GAX21122.1 - 4e-16 58.6 3.4 5.3e-16 58.2 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX21122.1 - 1.3e-05 25.6 0.3 7.8e-05 23.1 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX21122.1 - 0.00068 19.7 0.3 0.0016 18.5 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 GAX21122.1 - 0.0036 17.2 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAX21122.1 - 0.012 15.9 0.1 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 GAX21122.1 - 0.015 15.9 0.5 0.021 15.4 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX21122.1 - 0.069 13.2 0.7 9 6.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Ribonuc_red_lgC PF02867.15 GAX21123.1 - 4.8e-184 612.8 0.0 5.7e-184 612.5 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAX21123.1 - 1.1e-20 73.4 0.2 5.7e-20 71.1 0.0 2.3 3 0 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain Ribosomal_L28 PF00830.19 GAX21124.1 - 1.8e-16 60.1 3.4 1.8e-16 60.1 3.4 1.7 2 1 0 2 2 2 1 Ribosomal L28 family Phage_lysozyme2 PF18013.1 GAX21124.1 - 0.099 12.6 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Phage tail lysozyme Ndufs5 PF10200.9 GAX21125.1 - 2.1e-05 24.7 0.4 2.4e-05 24.5 0.4 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 GAX21125.1 - 0.003 17.7 0.4 0.003 17.7 0.4 1.9 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb RL10P_insert PF17777.1 GAX21126.1 - 3.2e-21 75.1 0.0 4.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GAX21126.1 - 1.9e-07 31.2 0.1 3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 WD40 PF00400.32 GAX21127.1 - 2.5e-40 135.7 17.3 1e-09 38.8 0.2 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX21127.1 - 4.9e-17 62.0 0.4 0.00042 20.5 0.0 5.8 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 GAX21127.1 - 3.4e-09 36.3 0.1 7.2e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 GAX21127.1 - 2.4e-07 30.9 1.3 0.31 10.9 0.0 4.5 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAX21127.1 - 0.016 14.6 0.1 0.14 11.5 0.0 2.4 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 GAX21127.1 - 0.018 14.4 0.0 4.9 6.3 0.0 3.1 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2574 PF10836.8 GAX21127.1 - 0.08 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) WD40_like PF17005.5 GAX21127.1 - 0.093 12.0 0.0 13 5.0 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain Trypan_PARP PF05887.11 GAX21127.1 - 2.1 8.3 13.1 1.6 8.7 11.3 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3783 PF12646.7 GAX21128.1 - 0.0038 17.1 7.2 0.96 9.5 0.1 5.2 6 0 0 6 6 6 2 Domain of unknown function (DUF3783) Ribosomal_S13_N PF08069.12 GAX21128.1 - 0.019 15.0 0.1 0.14 12.2 0.0 2.6 2 2 1 3 3 3 0 Ribosomal S13/S15 N-terminal domain DUF4287 PF14117.6 GAX21128.1 - 0.044 13.9 0.1 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) PocR PF10114.9 GAX21128.1 - 0.88 9.3 4.1 2 8.2 0.3 3.0 1 1 2 3 3 3 0 Sensory domain found in PocR Ribosomal_L9_C PF03948.14 GAX21129.1 - 4.7e-14 52.6 1.5 4.7e-14 52.6 1.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 GAX21129.1 - 2.6e-07 30.1 0.7 6.2e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain DUF2547 PF10818.8 GAX21129.1 - 1 10.3 0.1 1 10.3 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2547) NAD_binding_10 PF13460.6 GAX21130.1 - 1.7e-14 54.1 0.0 4.1e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX21130.1 - 5.3e-14 52.3 0.0 4.8e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 GAX21130.1 - 0.0007 19.6 0.0 0.026 14.5 0.1 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAX21130.1 - 0.0016 18.0 0.1 0.0076 15.7 0.0 2.2 3 1 1 4 4 4 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAX21130.1 - 0.0037 16.8 0.0 0.53 9.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase TrkA_N PF02254.18 GAX21130.1 - 0.1 12.9 0.1 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 GAX21130.1 - 0.14 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX21130.1 - 0.15 11.2 0.1 0.41 9.7 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DEAD PF00270.29 GAX21131.1 - 2.2e-43 148.1 0.3 3.1e-43 147.6 0.3 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX21131.1 - 2.5e-29 101.9 2.2 3.5e-28 98.2 0.6 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX21131.1 - 3.3e-06 27.2 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX21131.1 - 0.00036 19.8 0.1 0.00053 19.3 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 GAX21131.1 - 0.029 14.7 0.1 0.05 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX21131.1 - 0.085 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 GAX21131.1 - 0.089 12.1 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit HIT PF01230.23 GAX21132.1 - 4.7e-24 85.0 0.0 5.4e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAX21132.1 - 2e-16 60.5 0.0 2.2e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Glyco_trans_1_4 PF13692.6 GAX21133.1 - 1.7e-08 35.0 0.0 2.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX21133.1 - 3e-07 30.2 0.0 7.4e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX21133.1 - 0.00015 21.8 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAX21133.1 - 0.00024 21.6 0.0 0.00051 20.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX21133.1 - 0.038 14.4 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 HAD_2 PF13419.6 GAX21134.1 - 6e-07 29.7 0.0 0.00016 21.8 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX21134.1 - 4.3e-05 23.9 0.0 9.5e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zinc_ribbon_2 PF13240.6 GAX21134.1 - 0.00021 20.9 3.7 0.00021 20.9 3.7 2.3 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 GAX21134.1 - 0.0047 16.9 0.7 0.0047 16.9 0.7 2.0 3 0 0 3 3 3 1 Double zinc ribbon Hydrolase_like PF13242.6 GAX21134.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like zinc_ribbon_15 PF17032.5 GAX21134.1 - 0.055 14.2 0.0 0.14 13.0 0.0 1.7 1 0 0 1 1 1 0 zinc-ribbon family Response_reg PF00072.24 GAX21134.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Response regulator receiver domain zf-ribbon_3 PF13248.6 GAX21134.1 - 0.2 11.1 1.5 0.42 10.1 1.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Peptidase_S51 PF03575.17 GAX21135.1 - 2.4e-24 86.2 0.0 7.8e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S51 tRNA_U5-meth_tr PF05958.11 GAX21136.1 - 0.023 13.7 0.0 12 4.8 0.0 3.1 3 1 1 4 4 4 0 tRNA (Uracil-5-)-methyltransferase HTH_1 PF00126.27 GAX21136.1 - 0.041 13.8 0.1 0.16 11.9 0.1 2.0 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Glyco_transf_64 PF09258.10 GAX21138.1 - 3.9e-46 157.3 0.0 5.2e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain GCP_C_terminal PF04130.13 GAX21139.1 - 6.6e-56 190.0 10.1 1.3e-55 189.0 10.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAX21139.1 - 2.9e-45 155.2 0.3 6.7e-45 154.0 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF309 PF03745.14 GAX21139.1 - 0.075 12.7 0.3 0.51 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF309) MAD PF05557.13 GAX21140.1 - 8.5e-21 74.0 27.6 8.5e-21 74.0 27.6 3.6 2 2 0 2 2 2 1 Mitotic checkpoint protein DUF4748 PF15932.5 GAX21140.1 - 0.14 11.9 1.0 0.57 10.0 1.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) TetR_C_15 PF17918.1 GAX21140.1 - 4.2 8.2 9.2 21 5.9 1.5 3.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CHASE PF03924.13 GAX21141.1 - 3.2e-25 89.2 0.1 5.1e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.26 GAX21141.1 - 1.1e-21 77.4 0.0 3.2e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX21141.1 - 1.6e-12 47.6 0.0 3.5e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX21141.1 - 0.00044 20.2 0.2 0.0016 18.4 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 GAX21141.1 - 0.0044 17.0 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain COX8 PF02285.15 GAX21141.1 - 0.32 10.9 0.7 0.86 9.5 0.7 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII CHASE PF03924.13 GAX21142.1 - 2.6e-21 76.4 0.1 4.2e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.26 GAX21142.1 - 2.5e-20 73.1 0.0 4.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX21142.1 - 1.1e-12 48.1 0.0 2.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 GAX21142.1 - 0.0061 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain RT_RNaseH_2 PF17919.1 GAX21143.1 - 6.8e-30 103.1 0.0 1.7e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAX21143.1 - 1.3e-26 92.9 0.0 3.1e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAX21143.1 - 5.2e-19 68.6 0.2 3.2e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX21143.1 - 2.6e-14 53.4 0.0 8.8e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GAX21143.1 - 7.3e-09 35.6 0.0 1.7e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GAX21143.1 - 0.00012 22.2 1.0 0.0013 18.9 0.4 2.8 2 0 0 2 2 2 1 H2C2 zinc finger adh_short PF00106.25 GAX21144.1 - 1.2e-25 90.1 0.0 1.6e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX21144.1 - 1.3e-13 51.1 0.0 1.7e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX21144.1 - 0.00027 20.9 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAX21144.1 - 0.0009 19.2 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 GAX21144.1 - 0.0012 18.3 0.2 0.011 15.1 0.2 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NepR PF18557.1 GAX21144.1 - 0.053 13.2 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Anti-sigma factor NepR Epimerase PF01370.21 GAX21144.1 - 0.078 12.4 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX21144.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SRP54 PF00448.22 GAX21145.1 - 8.3e-65 218.1 0.1 1.5e-64 217.3 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAX21145.1 - 2e-06 28.3 0.4 6.7e-06 26.6 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain SRP54_N PF02881.19 GAX21145.1 - 5.7e-06 26.5 0.2 1.7e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 GAX21145.1 - 0.00013 21.8 0.1 0.00028 20.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAX21145.1 - 0.00074 19.5 2.3 0.03 14.3 0.2 2.9 2 1 1 3 3 3 1 NACHT domain AAA_24 PF13479.6 GAX21145.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX21145.1 - 0.0025 18.2 0.1 0.0062 16.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 GAX21145.1 - 0.012 15.5 1.0 0.074 12.9 0.2 2.4 2 1 0 2 2 2 0 Helicase AAA_22 PF13401.6 GAX21145.1 - 0.013 15.8 2.2 0.03 14.6 0.1 2.5 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAX21145.1 - 0.028 14.9 0.0 0.076 13.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 GAX21145.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 GAX21145.1 - 0.036 14.1 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 GAX21145.1 - 0.037 14.3 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ORC3_N PF07034.11 GAX21145.1 - 0.043 12.9 0.1 0.064 12.4 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus AAA_17 PF13207.6 GAX21145.1 - 0.054 13.9 2.3 0.78 10.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 GAX21145.1 - 0.059 12.6 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 GAX21145.1 - 0.075 13.0 0.1 0.24 11.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 GAX21145.1 - 0.08 13.0 0.7 0.47 10.5 0.3 2.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX21145.1 - 0.089 12.7 0.5 1.6 8.6 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX21145.1 - 0.094 12.2 0.1 4.4 6.8 0.1 2.2 1 1 1 2 2 2 0 P-loop containing dynein motor region Herpes_Helicase PF02689.14 GAX21145.1 - 0.11 10.5 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Helicase NTPase_1 PF03266.15 GAX21145.1 - 0.12 12.3 0.2 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 NTPase PG_isomerase_N PF18353.1 GAX21145.1 - 0.14 12.5 0.5 3.3 8.1 0.2 2.4 2 0 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain Fer4_NifH PF00142.18 GAX21145.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF87 PF01935.17 GAX21145.1 - 0.19 11.8 2.1 0.77 9.8 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain SET PF00856.28 GAX21146.1 - 0.00043 20.7 0.0 0.011 16.1 0.0 3.1 2 1 1 3 3 3 1 SET domain SAF PF08666.12 GAX21146.1 - 0.045 14.4 0.1 22 5.8 0.0 3.3 4 0 0 4 4 4 0 SAF domain A_deaminase PF00962.22 GAX21147.1 - 2.9e-32 112.3 0.1 8.4e-31 107.5 0.1 2.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase SBDS PF01172.18 GAX21148.1 - 1.2e-11 44.5 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Alpha_kinase PF02816.18 GAX21149.1 - 2.3e-37 128.9 0.0 2.6e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.18 GAX21150.1 - 2e-48 165.0 0.0 2.7e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Aminotran_1_2 PF00155.21 GAX21151.1 - 2.4e-84 283.6 0.0 2.8e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.25 GAX21152.1 - 8.7e-30 104.0 0.0 1.8e-29 102.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21152.1 - 1e-26 93.8 0.0 2.3e-26 92.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX21152.1 - 0.0084 14.9 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX21152.1 - 0.073 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RHH_5 PF07878.11 GAX21152.1 - 0.15 12.0 0.0 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 SNase PF00565.17 GAX21153.1 - 5.2e-22 78.4 0.0 8.9e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PSI_PsaH PF03244.14 GAX21153.1 - 0.036 13.6 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI Kinesin PF00225.23 GAX21154.1 - 8.8e-97 324.0 0.1 5.4e-96 321.4 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX21154.1 - 2.1e-21 76.4 0.0 7.5e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Mvb12 PF09452.10 GAX21154.1 - 0.0035 17.7 0.5 0.011 16.1 0.5 1.8 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 EMP24_GP25L PF01105.24 GAX21154.1 - 0.028 14.3 0.3 0.028 14.3 0.3 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4201 PF13870.6 GAX21154.1 - 0.062 13.0 17.2 0.55 10.0 9.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 GAX21154.1 - 0.23 10.3 17.9 0.61 8.9 6.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF5631 PF18645.1 GAX21154.1 - 0.26 11.7 1.3 4.3 7.8 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5631) AAA_23 PF13476.6 GAX21154.1 - 0.26 11.7 9.4 1.6 9.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain NRBF2 PF08961.10 GAX21154.1 - 2.1 7.9 10.8 1.2 8.8 3.4 2.3 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator RPW8 PF05659.11 GAX21154.1 - 2.2 8.0 8.0 0.22 11.2 0.4 2.7 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CDC37_N PF03234.14 GAX21154.1 - 2.2 9.2 8.8 0.45 11.4 1.5 2.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Prefoldin PF02996.17 GAX21154.1 - 3.2 7.7 13.3 0.5 10.3 2.6 3.2 2 2 0 2 2 2 0 Prefoldin subunit DUF745 PF05335.13 GAX21154.1 - 8.7 6.0 15.5 9.4 5.9 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) UFD1 PF03152.14 GAX21155.1 - 9.5e-28 96.8 0.0 1.8e-27 95.9 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 S-methyl_trans PF02574.16 GAX21157.1 - 5e-53 180.6 0.0 5.7e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase CBM_6 PF03422.15 GAX21158.1 - 6.5e-43 146.0 5.9 5.1e-22 78.5 0.4 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX21158.1 - 4.7e-25 88.6 10.9 8.8e-25 87.7 10.9 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX21158.1 - 1.3e-18 67.2 4.4 6.3e-09 36.0 0.2 2.4 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX21158.1 - 0.0019 18.4 4.2 0.013 15.7 1.1 2.8 2 1 0 2 2 2 1 Carbohydrate binding module (family 35) DUF1719 PF08224.11 GAX21158.1 - 0.059 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) PWWP PF00855.17 GAX21159.1 - 0.042 14.2 0.5 0.1 13.0 0.5 1.6 1 0 0 1 1 1 0 PWWP domain DUF4638 PF15472.6 GAX21159.1 - 0.98 9.1 8.6 0.47 10.1 6.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4638) CesT PF05932.13 GAX21162.1 - 0.094 12.8 1.4 0.23 11.6 1.4 1.6 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family TFIIA PF03153.13 GAX21162.1 - 0.29 11.1 11.2 0.37 10.7 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDZ PF00595.24 GAX21163.1 - 9.2e-07 29.1 0.1 2.7e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX21163.1 - 0.00017 21.4 0.0 0.00047 19.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Peripla_BP_4 PF13407.6 GAX21165.1 - 4e-42 144.6 0.0 5.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain 7tm_3 PF00003.22 GAX21165.1 - 3.8e-37 128.3 15.7 5.1e-37 127.9 15.7 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_1 PF00532.21 GAX21165.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Radical_SAM PF04055.21 GAX21165.1 - 0.041 14.3 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily PucR PF07905.11 GAX21165.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Guanylate_cyc PF00211.20 GAX21166.1 - 9.5e-43 145.9 0.0 1.6e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX21166.1 - 7.4e-35 120.8 3.3 2.5e-34 119.0 1.2 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 GAX21166.1 - 7.2e-05 22.8 0.0 0.0002 21.3 0.0 1.8 1 0 0 1 1 1 1 CHASE domain DUF1624 PF07786.12 GAX21166.1 - 0.062 12.8 0.1 0.41 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1624) DHR-2 PF06920.13 GAX21167.1 - 0.00015 20.6 0.0 0.00031 19.5 0.0 1.5 1 0 0 1 1 1 1 Dock homology region 2 U-box PF04564.15 GAX21168.1 - 1.2e-20 73.5 0.1 1.9e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GAX21168.1 - 1.4e-07 31.2 1.2 2.1e-06 27.4 1.0 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 GAX21168.1 - 0.00053 20.2 1.2 0.0013 18.9 0.6 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX21168.1 - 0.00068 19.6 0.2 0.0017 18.4 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAX21168.1 - 0.00076 19.5 0.3 0.0017 18.4 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 GAX21168.1 - 0.0013 18.1 1.0 0.0022 17.4 1.0 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 GAX21168.1 - 0.0049 16.7 0.5 0.011 15.6 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 GAX21168.1 - 0.02 15.0 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Abhydrolase_6 PF12697.7 GAX21169.1 - 3.2e-07 31.2 0.2 4.1e-07 30.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAX21169.1 - 3.5e-06 26.9 0.0 6.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAX21169.1 - 2.8e-05 23.7 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 GAX21169.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 GAX21169.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 GAX21169.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 GAX21169.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Pox_I5 PF04713.12 GAX21170.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus protein I5 DUF4817 PF16087.5 GAX21172.1 - 0.085 12.7 0.0 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) DBD_HTH PF18430.1 GAX21174.1 - 0.0018 18.0 0.2 0.0039 16.9 0.2 1.5 1 0 0 1 1 1 1 Putative DNA-binding domain XK-related PF09815.9 GAX21176.1 - 0.026 13.6 1.4 0.31 10.1 0.3 2.2 2 0 0 2 2 2 0 XK-related protein DUF4131 PF13567.6 GAX21176.1 - 0.18 11.4 7.0 0.1 12.3 1.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Glyco_transf_49 PF13896.6 GAX21177.1 - 5e-41 141.1 0.1 7e-35 120.9 0.1 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.6 GAX21178.1 - 3.1e-44 151.7 0.4 7.6e-42 143.8 0.4 2.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAX21178.1 - 0.03 14.1 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Polysacc_deac_1 PF01522.21 GAX21179.1 - 0.0045 16.9 0.0 0.025 14.5 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide deacetylase DUF4366 PF14283.6 GAX21179.1 - 0.098 12.7 0.0 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) PPC PF04151.15 GAX21180.1 - 6.5 7.9 9.9 3.6 8.7 1.0 2.7 1 1 1 2 2 2 0 Bacterial pre-peptidase C-terminal domain Chloroa_b-bind PF00504.21 GAX21181.1 - 1.3e-37 129.8 0.2 2.2e-37 129.1 0.2 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4245 PF14030.6 GAX21181.1 - 0.077 13.0 1.3 0.12 12.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) rve PF00665.26 GAX21182.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.14 GAX21183.1 - 3.3e-13 49.8 0.0 5.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2748 PF10871.8 GAX21183.1 - 0.085 11.5 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) Retrotran_gag_2 PF14223.6 GAX21184.1 - 3.6e-06 26.7 0.0 5.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AAA_assoc_2 PF16193.5 GAX21184.1 - 0.12 12.8 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain DUF3452 PF11934.8 GAX21184.1 - 0.15 11.7 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) gag_pre-integrs PF13976.6 GAX21185.1 - 0.00087 19.1 0.1 0.0018 18.1 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UL17 PF17640.2 GAX21186.1 - 0.01 15.8 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized UL17 Dynamin_M PF01031.20 GAX21187.1 - 4.7e-23 81.8 0.4 1.4e-15 57.3 0.1 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 GAX21187.1 - 5.6e-17 62.3 0.0 1.3e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAX21187.1 - 6e-05 23.1 0.1 0.00026 21.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAX21187.1 - 0.004 17.7 0.5 0.025 15.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Alph_Pro_TM PF09608.10 GAX21188.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Sec23_trunk PF04811.15 GAX21190.1 - 4.4e-72 242.6 0.0 6.7e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX21190.1 - 2.7e-23 81.7 0.0 4.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAX21190.1 - 7.8e-19 68.2 0.1 1.3e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAX21190.1 - 6.2e-15 55.0 6.3 1.4e-14 53.8 6.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAX21190.1 - 1.5e-07 31.2 0.0 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Endothelin PF00322.17 GAX21190.1 - 0.53 9.9 2.4 1.2 8.8 2.4 1.6 1 0 0 1 1 1 0 Endothelin family MRNIP PF15749.5 GAX21190.1 - 1.1 10.0 2.3 1.9 9.3 2.3 1.3 1 0 0 1 1 1 0 MRN-interacting protein GFO_IDH_MocA PF01408.22 GAX21191.1 - 1.9e-11 44.8 1.7 5.4e-11 43.4 1.7 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Adaptin_N PF01602.20 GAX21192.1 - 2.1e-110 369.8 2.6 2.4e-110 369.6 2.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAX21192.1 - 4.1e-08 33.4 3.3 0.0047 17.0 0.5 3.0 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX21192.1 - 0.00045 20.7 2.7 0.25 11.9 0.0 5.9 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 GAX21192.1 - 0.0027 18.1 9.5 0.63 10.5 0.0 6.0 5 1 1 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 GAX21192.1 - 0.042 14.4 0.6 1.1 9.9 0.0 3.2 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region MOR2-PAG1_N PF14222.6 GAX21192.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Exo70 PF03081.15 GAX21192.1 - 0.12 11.4 0.3 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Exo70 exocyst complex subunit RTP1_C1 PF10363.9 GAX21192.1 - 0.12 12.5 1.8 3.9 7.7 0.0 3.8 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 GAX21192.1 - 0.23 11.6 1.0 39 4.4 0.0 3.4 3 0 0 3 3 3 0 V-ATPase subunit H HEAT PF02985.22 GAX21192.1 - 0.76 10.2 10.5 2.9 8.4 0.0 5.7 7 0 0 7 7 7 0 HEAT repeat ANAPC4_WD40 PF12894.7 GAX21193.1 - 1.2e-06 28.7 0.2 0.011 16.1 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 GAX21193.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term RAB3GAP2_N PF14655.6 GAX21193.1 - 0.0034 16.7 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 GAX21193.1 - 0.026 15.4 0.4 1.3 10.0 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat POTRA_2 PF08479.11 GAX21195.1 - 0.00026 20.8 0.3 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 1 POTRA domain, ShlB-type Bac_surface_Ag PF01103.23 GAX21195.1 - 0.083 12.4 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Surface antigen ArlS_N PF18719.1 GAX21197.1 - 0.00025 21.2 0.1 0.074 13.3 0.0 2.4 2 0 0 2 2 2 2 ArlS sensor domain SIR2 PF02146.17 GAX21198.1 - 2.4e-34 118.8 0.1 1.5e-33 116.2 0.1 2.1 1 1 0 1 1 1 1 Sir2 family RBM39linker PF15519.6 GAX21198.1 - 0.58 11.3 0.1 0.58 11.3 0.1 2.3 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein BET PF17035.5 GAX21198.1 - 0.67 10.2 3.4 2.7 8.3 1.5 2.5 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation MSP PF01716.18 GAX21199.1 - 1.6e-88 296.0 0.2 1.9e-88 295.8 0.2 1.0 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide SCO1-SenC PF02630.14 GAX21200.1 - 0.004 17.1 0.3 0.0084 16.0 0.3 1.6 1 0 0 1 1 1 1 SCO1/SenC DUF503 PF04456.12 GAX21200.1 - 0.0094 15.8 2.5 0.0094 15.8 2.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF503) ATP-synt_S1 PF05827.12 GAX21200.1 - 0.051 13.4 5.2 0.029 14.2 1.5 2.2 2 1 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) EMC3_TMCO1 PF01956.16 GAX21200.1 - 2.6 7.7 9.7 16 5.2 9.7 2.2 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like ClpS PF02617.17 GAX21200.1 - 3.7 7.4 7.5 1.4 8.7 1.7 2.5 1 1 1 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS PsbQ PF05757.11 GAX21201.1 - 0.0039 17.0 12.5 0.072 12.8 12.5 2.5 1 1 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) TPP_enzyme_C PF02775.21 GAX21201.1 - 0.47 10.2 3.4 0.25 11.1 0.5 2.0 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain LRR_8 PF13855.6 GAX21202.1 - 9.4e-41 137.4 124.7 1.4e-07 31.2 5.0 22.4 18 3 9 27 27 27 20 Leucine rich repeat LRR_4 PF12799.7 GAX21202.1 - 6.6e-37 124.9 118.4 0.00028 21.2 0.3 26.1 20 7 8 30 30 30 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX21202.1 - 5e-11 41.5 80.7 1.3 9.8 0.1 25.9 28 1 1 29 29 29 3 Leucine Rich Repeat LRR_6 PF13516.6 GAX21202.1 - 2.4e-07 30.3 55.5 22 5.4 0.0 22.6 25 0 0 25 25 25 1 Leucine Rich repeat DUF3338 PF11819.8 GAX21202.1 - 0.00092 19.2 0.2 5.1 7.1 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF3338) LRRNT_2 PF08263.12 GAX21202.1 - 0.017 15.5 0.4 0.017 15.5 0.4 6.5 8 0 0 8 8 8 0 Leucine rich repeat N-terminal domain COX5B PF01215.19 GAX21202.1 - 0.16 11.7 0.2 3.3 7.4 0.0 3.1 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Vb INSIG PF07281.12 GAX21203.1 - 5.7e-05 22.9 0.4 0.00017 21.3 0.2 1.9 1 1 0 2 2 2 1 Insulin-induced protein (INSIG) Na_Pi_cotrans PF02690.15 GAX21204.1 - 5e-36 123.9 38.3 1.1e-20 74.2 11.0 3.1 2 1 0 2 2 2 2 Na+/Pi-cotransporter PDR_assoc PF08370.11 GAX21204.1 - 0.00097 18.8 1.8 0.0039 16.9 1.8 2.0 1 0 0 1 1 1 1 Plant PDR ABC transporter associated DUF953 PF06110.11 GAX21204.1 - 0.062 12.9 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) TMEM213 PF15192.6 GAX21204.1 - 0.074 13.0 0.3 0.29 11.1 0.3 2.0 1 0 0 1 1 1 0 TMEM213 family FeoB_associated PF12669.7 GAX21204.1 - 0.26 11.7 1.6 0.73 10.3 0.0 2.7 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF4886 PF16227.5 GAX21205.1 - 2.8e-10 39.8 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4886) Tad PF13400.6 GAX21205.1 - 0.0084 16.4 1.5 0.1 12.9 0.2 2.3 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like DUF4448 PF14610.6 GAX21205.1 - 0.018 14.8 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4519 PF15012.6 GAX21205.1 - 0.04 14.1 0.2 0.083 13.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Lipase_GDSL_2 PF13472.6 GAX21205.1 - 0.088 13.2 0.1 0.28 11.6 0.0 1.7 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF1970 PF09301.10 GAX21205.1 - 0.13 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Copine PF07002.16 GAX21206.1 - 2.6e-48 164.3 0.0 3.6e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX21206.1 - 7.8e-07 29.3 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.9 GAX21206.1 - 1.1e-06 28.9 0.1 1.9e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.6 GAX21207.1 - 0.052 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Spore_III_AB PF09548.10 GAX21207.1 - 0.058 13.5 0.0 0.2 11.8 0.0 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Thiolase_N PF00108.23 GAX21209.1 - 4.1e-81 272.1 0.2 8.1e-81 271.2 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAX21209.1 - 2.7e-45 153.0 2.5 4.8e-45 152.2 0.6 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAX21209.1 - 0.0021 17.7 0.2 0.0047 16.5 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Podoplanin PF05808.11 GAX21210.1 - 0.00058 20.0 0.0 0.00097 19.3 0.0 1.4 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 GAX21210.1 - 0.0035 17.9 0.0 0.0071 16.9 0.0 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Myc_target_1 PF15179.6 GAX21210.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Myc target protein 1 Ribosomal_60s PF00428.19 GAX21211.1 - 3.9e-16 59.4 3.0 4.9e-16 59.1 3.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF563 PF04577.14 GAX21213.1 - 2.3e-06 27.9 0.0 5.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TatC PF00902.18 GAX21213.1 - 0.16 11.8 1.6 0.18 11.6 0.6 1.5 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) Pkinase_Tyr PF07714.17 GAX21214.1 - 5.7e-38 130.7 0.0 8.3e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX21214.1 - 6.5e-31 107.7 0.0 1.1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX21214.1 - 1.6e-06 27.2 0.0 2.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX21214.1 - 0.015 15.2 0.3 0.071 13.0 0.0 2.0 2 1 0 3 3 3 0 Phosphotransferase enzyme family PIP49_C PF12260.8 GAX21214.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 YrbL-PhoP_reg PF10707.9 GAX21214.1 - 0.06 12.9 0.1 0.2 11.1 0.0 1.8 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL LNP1 PF15419.6 GAX21214.1 - 0.11 12.7 2.9 0.22 11.8 2.9 1.5 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 DUF1435 PF07256.12 GAX21216.1 - 0.092 12.9 4.5 0.32 11.1 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) CENP-L PF13092.6 GAX21217.1 - 1.4e-10 41.6 0.0 2.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 TPR_8 PF13181.6 GAX21218.1 - 0.0062 16.7 8.4 0.14 12.4 0.7 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat FlhC PF05280.11 GAX21218.1 - 0.07 12.8 0.4 0.49 10.1 0.3 2.1 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) nsp8 PF08717.10 GAX21218.1 - 0.93 9.3 7.2 0.082 12.8 1.9 1.9 2 0 0 2 2 2 0 nsp8 replicase TPR_1 PF00515.28 GAX21218.1 - 6.6 6.7 9.2 1.3 8.9 0.9 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat SBDS PF01172.18 GAX21219.1 - 3.5e-12 46.2 0.0 4.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Alpha_kinase PF02816.18 GAX21220.1 - 5.4e-35 121.2 0.0 6.2e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Aminotran_1_2 PF00155.21 GAX21221.1 - 3e-84 283.3 0.0 3.5e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.25 GAX21222.1 - 4.6e-30 104.9 0.0 1.1e-29 103.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21222.1 - 2.7e-27 95.7 0.0 5e-27 94.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX21222.1 - 0.0032 16.3 0.0 0.0067 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RHH_5 PF07878.11 GAX21222.1 - 0.068 13.1 0.2 0.43 10.5 0.1 2.4 3 0 0 3 3 3 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 APH PF01636.23 GAX21222.1 - 0.088 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinesin PF00225.23 GAX21223.1 - 1.9e-96 322.9 0.1 1.1e-95 320.4 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX21223.1 - 3.1e-21 75.9 0.0 1.2e-20 73.9 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Mvb12 PF09452.10 GAX21223.1 - 0.0032 17.8 0.5 0.011 16.1 0.5 1.9 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 DUF4201 PF13870.6 GAX21223.1 - 0.014 15.2 17.6 0.13 12.0 9.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) EMP24_GP25L PF01105.24 GAX21223.1 - 0.028 14.3 0.3 0.028 14.3 0.3 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 GAX21223.1 - 0.064 12.1 18.0 0.15 10.9 6.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_23 PF13476.6 GAX21223.1 - 0.077 13.5 8.4 1.6 9.2 0.2 2.5 2 0 0 2 2 2 0 AAA domain RPW8 PF05659.11 GAX21223.1 - 2 8.1 8.2 0.22 11.2 0.4 2.8 3 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prefoldin PF02996.17 GAX21223.1 - 2.2 8.2 14.3 0.54 10.2 2.7 3.3 2 2 0 2 2 2 0 Prefoldin subunit CDC37_N PF03234.14 GAX21223.1 - 2.5 9.0 8.7 0.53 11.2 1.7 2.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding PRKG1_interact PF15898.5 GAX21223.1 - 4 8.4 16.4 16 6.5 7.6 2.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain NRBF2 PF08961.10 GAX21223.1 - 7.3 6.2 11.3 4 7.0 3.9 2.3 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator UFD1 PF03152.14 GAX21224.1 - 5.7e-28 97.5 0.0 1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 S-methyl_trans PF02574.16 GAX21226.1 - 1.4e-51 175.9 0.0 1.6e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase CBM_6 PF03422.15 GAX21227.1 - 4.2e-42 143.4 4.7 6e-21 75.0 0.3 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX21227.1 - 4.5e-26 91.9 13.5 1e-25 90.8 13.5 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX21227.1 - 1.1e-17 64.1 4.8 5.1e-09 36.2 0.3 2.5 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX21227.1 - 0.00013 22.3 2.6 0.0031 17.8 0.2 2.5 2 0 0 2 2 2 1 Carbohydrate binding module (family 35) G-gamma PF00631.22 GAX21227.1 - 0.1 12.6 0.0 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 GGL domain Pro_isomerase PF00160.21 GAX21228.1 - 1.6e-17 64.2 0.0 2.1e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD E1-E2_ATPase PF00122.20 GAX21229.1 - 1.2e-43 148.7 15.4 5.8e-43 146.5 4.3 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX21229.1 - 2e-29 102.6 5.4 2e-29 102.6 5.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAX21229.1 - 3.5e-19 69.9 0.5 9.8e-15 55.4 0.3 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX21229.1 - 1.4e-17 63.1 0.2 8.7e-17 60.6 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAX21229.1 - 2.7e-14 53.0 0.0 2.9e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAX21229.1 - 0.0043 16.8 1.1 0.0086 15.8 1.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX21229.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5453 PF17534.2 GAX21229.1 - 0.64 9.9 3.8 0.42 10.5 0.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Sulfotransfer_1 PF00685.27 GAX21230.1 - 0.0021 17.6 0.5 0.0043 16.6 0.2 1.7 1 1 1 2 2 2 1 Sulfotransferase domain PAP_fibrillin PF04755.12 GAX21231.1 - 1.2e-14 54.7 0.0 9.9e-14 51.7 0.0 2.1 1 1 0 1 1 1 1 PAP_fibrillin DDHD PF02862.17 GAX21231.1 - 0.13 12.4 2.2 0.18 12.0 2.2 1.3 1 0 0 1 1 1 0 DDHD domain EIIBC-GUT_N PF03612.14 GAX21231.1 - 4.6 6.9 6.1 7.5 6.3 4.9 2.0 2 1 1 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus Ank_2 PF12796.7 GAX21232.1 - 6.4e-07 29.9 0.0 1.6e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX21232.1 - 0.00046 20.4 0.0 0.017 15.4 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX21232.1 - 0.00059 20.3 0.0 0.63 10.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21232.1 - 0.003 17.9 0.0 1 10.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAX21232.1 - 0.12 12.9 0.0 5.8 7.5 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 GAX21233.1 - 1.5e-192 637.6 0.0 1.1e-67 228.2 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21233.1 - 1.6e-78 263.6 0.0 4e-28 98.4 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 GAX21233.1 - 4.3e-13 49.2 0.0 0.0051 16.2 0.0 4.7 5 1 0 5 5 5 3 Kinase-like Pkinase_fungal PF17667.1 GAX21233.1 - 4e-09 35.7 0.0 0.00033 19.5 0.0 2.7 3 0 0 3 3 3 2 Fungal protein kinase Kdo PF06293.14 GAX21233.1 - 7.3e-06 25.5 0.2 0.017 14.5 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 GAX21233.1 - 0.0071 15.4 0.8 1.6 7.6 0.1 2.3 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase APH PF01636.23 GAX21233.1 - 0.067 13.1 0.2 12 5.8 0.0 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX21233.1 - 0.13 11.8 0.1 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase NPBW PF15180.6 GAX21234.1 - 0.9 9.4 5.0 0.27 11.1 0.4 2.4 2 0 0 2 2 2 0 Neuropeptides B and W PAS_6 PF08348.11 GAX21234.1 - 2.3 8.1 10.1 5.1 7.0 0.2 3.5 3 0 0 3 3 3 0 YheO-like PAS domain Pectate_lyase_3 PF12708.7 GAX21235.1 - 0.0032 17.3 0.0 1.4 8.7 0.0 3.2 3 1 0 3 3 3 2 Pectate lyase superfamily protein GTP_cyclohydro2 PF00925.20 GAX21235.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II Gaa1 PF04114.14 GAX21236.1 - 9.7e-23 80.9 10.3 1.8e-21 76.8 10.3 2.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component DGF-1_C PF11040.8 GAX21237.1 - 0.0036 17.3 0.3 0.02 14.8 0.3 2.3 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus MMtag PF10159.9 GAX21237.1 - 0.12 12.6 0.1 0.12 12.6 0.1 4.1 5 0 0 5 5 5 0 Multiple myeloma tumor-associated PIG-P PF08510.12 GAX21238.1 - 1.6e-08 34.5 3.2 2.7e-08 33.7 3.2 1.4 1 1 0 1 1 1 1 PIG-P DUF3149 PF11346.8 GAX21238.1 - 0.016 14.8 1.5 0.031 13.9 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) TMEM208_SND2 PF05620.11 GAX21238.1 - 0.25 11.1 0.6 0.41 10.4 0.2 1.6 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Mito_carr PF00153.27 GAX21240.1 - 1.2e-49 166.1 4.6 7.1e-18 64.3 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 GAX21241.1 - 0.0002 21.1 0.1 1.5 8.5 0.0 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Toxin_38 PF14866.6 GAX21241.1 - 0.059 13.7 0.7 0.13 12.5 0.7 1.5 1 0 0 1 1 1 0 Potassium channel toxin Aa_trans PF01490.18 GAX21242.1 - 2.8e-30 105.3 21.8 3.7e-30 105.0 21.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_holin_2_4 PF16082.5 GAX21242.1 - 1.7 8.4 3.8 11 5.8 0.3 2.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF2976 PF11190.8 GAX21242.1 - 8.4 6.3 8.2 0.49 10.2 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) CaMKII_AD PF08332.10 GAX21243.1 - 5.8e-76 252.8 0.0 1.6e-19 70.4 0.0 4.1 4 0 0 4 4 4 4 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 GAX21243.1 - 3.3e-49 165.7 0.4 3.6e-12 46.6 0.0 4.2 4 0 0 4 4 4 4 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 GAX21243.1 - 1.4e-45 154.4 0.0 9.8e-10 38.8 0.0 4.8 4 1 0 4 4 4 4 SnoaL-like domain SnoaL_2 PF12680.7 GAX21243.1 - 6.6e-30 103.8 0.0 2.5e-07 31.2 0.0 4.2 4 0 0 4 4 4 4 SnoaL-like domain SnoaL_4 PF13577.6 GAX21243.1 - 2.3e-17 63.3 13.7 5.4e-05 23.3 0.1 6.8 4 4 0 4 4 4 4 SnoaL-like domain DUF3225 PF11533.8 GAX21243.1 - 9.2e-07 28.6 0.3 2.3 8.0 0.0 4.8 4 2 0 4 4 4 2 Protein of unknown function (DUF3225) DUF959 PF06121.14 GAX21243.1 - 8.9e-05 22.8 0.7 8.2 6.6 0.0 4.1 4 0 0 4 4 4 1 Domain of Unknown Function (DUF959) MecA_N PF05223.11 GAX21243.1 - 0.00072 19.8 0.8 46 4.3 0.0 4.9 5 0 0 5 5 5 0 NTF2-like N-terminal transpeptidase domain Herpes_gE PF02480.16 GAX21243.1 - 0.00094 18.0 0.0 5 5.8 0.0 3.8 1 1 0 4 4 4 1 Alphaherpesvirus glycoprotein E DUF3692 PF12469.8 GAX21243.1 - 0.0029 17.8 0.0 48 4.2 0.0 4.2 4 0 0 4 4 4 0 CRISPR-associated protein Endopep_inhib PF16800.5 GAX21243.1 - 0.0044 17.0 2.2 16 5.4 0.1 4.1 4 0 0 4 4 4 0 IseA DL-endopeptidase inhibitor DUF4101 PF13355.6 GAX21243.1 - 0.021 15.3 5.2 27 5.2 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4101) Skp1 PF01466.19 GAX21243.1 - 0.021 14.9 0.0 27 5.0 0.0 4.3 4 0 0 4 4 4 0 Skp1 family, dimerisation domain FB_lectin PF07367.11 GAX21243.1 - 0.023 14.6 0.1 32 4.4 0.0 3.5 3 0 0 3 3 3 0 Fungal fruit body lectin NTF2 PF02136.20 GAX21243.1 - 0.032 14.8 0.0 36 4.9 0.0 4.0 4 1 0 4 4 4 0 Nuclear transport factor 2 (NTF2) domain PilJ_C PF18223.1 GAX21243.1 - 0.16 12.4 7.5 40 4.8 0.2 4.3 4 0 0 4 4 4 0 Pili PilJ C-terminal domain EpoR_lig-bind PF09067.10 GAX21243.1 - 0.18 12.0 0.0 1.7e+02 2.4 0.0 3.8 4 0 0 4 4 4 0 Erythropoietin receptor, ligand binding Dynactin_p62 PF05502.13 GAX21244.1 - 0.0001 21.3 15.2 0.00028 19.8 0.0 3.3 1 1 1 2 2 2 1 Dynactin p62 family CaMKII_AD PF08332.10 GAX21245.1 - 1e-59 200.3 0.0 4e-19 69.0 0.0 3.1 3 0 0 3 3 3 3 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 GAX21245.1 - 5.3e-38 129.7 0.0 1.9e-12 47.6 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 GAX21245.1 - 2.8e-33 114.7 0.0 1.5e-09 38.1 0.0 3.6 3 1 0 3 3 3 3 SnoaL-like domain SnoaL_2 PF12680.7 GAX21245.1 - 5.2e-25 88.1 0.0 3.3e-08 34.1 0.0 3.2 3 0 0 3 3 3 3 SnoaL-like domain SnoaL_4 PF13577.6 GAX21245.1 - 3.3e-13 49.9 7.3 0.00058 20.0 0.3 5.6 4 2 0 4 4 4 3 SnoaL-like domain DUF3225 PF11533.8 GAX21245.1 - 1.1e-05 25.1 0.2 2.1 8.1 0.0 4.0 4 1 0 4 4 4 2 Protein of unknown function (DUF3225) DUF959 PF06121.14 GAX21245.1 - 9.2e-05 22.8 0.5 9.4 6.4 0.0 3.2 3 0 0 3 3 3 2 Domain of Unknown Function (DUF959) Herpes_gE PF02480.16 GAX21245.1 - 0.0046 15.8 0.0 14 4.3 0.0 3.0 1 1 0 3 3 3 0 Alphaherpesvirus glycoprotein E MecA_N PF05223.11 GAX21245.1 - 0.017 15.4 1.4 13 6.1 0.0 3.9 5 0 0 5 5 4 0 NTF2-like N-terminal transpeptidase domain NTF2 PF02136.20 GAX21245.1 - 0.024 15.2 0.0 7.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Nuclear transport factor 2 (NTF2) domain Anth_synt_I_N PF04715.13 GAX21245.1 - 0.033 14.4 0.0 36 4.6 0.0 3.2 3 0 0 3 3 3 0 Anthranilate synthase component I, N terminal region Mvb12 PF09452.10 GAX21245.1 - 0.033 14.6 0.0 25 5.4 0.0 3.3 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 PilJ_C PF18223.1 GAX21245.1 - 0.047 14.2 2.1 26 5.4 0.0 3.4 3 0 0 3 3 3 0 Pili PilJ C-terminal domain DUF3692 PF12469.8 GAX21245.1 - 0.053 13.7 0.0 29 4.9 0.0 3.2 2 1 1 3 3 3 0 CRISPR-associated protein Endopep_inhib PF16800.5 GAX21245.1 - 0.11 12.4 0.4 28 4.6 0.0 3.0 3 0 0 3 3 3 0 IseA DL-endopeptidase inhibitor DUF4101 PF13355.6 GAX21245.1 - 0.12 12.9 1.3 67 4.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4101) SinI PF08671.10 GAX21245.1 - 0.58 10.0 1.6 1.5 8.7 0.1 2.6 3 0 0 3 3 3 0 Anti-repressor SinI Lon_C PF05362.13 GAX21246.1 - 2e-73 246.3 0.0 5e-73 245.0 0.0 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 GAX21246.1 - 2.5e-25 89.6 0.2 1.3e-24 87.2 0.0 2.3 3 0 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GAX21246.1 - 5.2e-22 78.7 0.0 1.5e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX21246.1 - 4.4e-08 33.2 0.0 4.1e-07 30.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 GAX21246.1 - 6.4e-08 32.5 0.0 1.7e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 GAX21246.1 - 5.5e-06 26.6 0.0 1.9e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 GAX21246.1 - 0.0001 21.3 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 GAX21246.1 - 0.00031 21.0 0.8 0.02 15.1 0.0 3.4 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 GAX21246.1 - 0.0011 18.8 0.0 0.0036 17.1 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 GAX21246.1 - 0.0026 17.5 0.2 0.019 14.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 GAX21246.1 - 0.004 16.4 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 GAX21246.1 - 0.0078 16.6 2.2 0.018 15.4 0.0 2.6 3 1 0 3 3 1 1 AAA ATPase domain AAA_18 PF13238.6 GAX21246.1 - 0.011 16.3 0.0 0.037 14.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 GAX21246.1 - 0.013 15.6 0.4 0.062 13.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_7 PF12775.7 GAX21246.1 - 0.014 14.9 0.2 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Phage_connect_1 PF05135.13 GAX21246.1 - 0.014 15.8 0.3 0.057 13.9 0.3 2.1 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein NTPase_1 PF03266.15 GAX21246.1 - 0.022 14.7 1.3 0.95 9.4 0.0 3.4 3 1 1 4 4 4 0 NTPase MCM PF00493.23 GAX21246.1 - 0.024 13.7 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain IstB_IS21 PF01695.17 GAX21246.1 - 0.028 14.2 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 GAX21246.1 - 0.046 14.0 0.1 0.22 11.8 0.1 2.1 1 0 0 1 1 1 0 AAA domain DUF3235 PF11574.8 GAX21246.1 - 0.056 14.3 0.0 0.16 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Exonuc_VII_L PF02601.15 GAX21246.1 - 0.066 12.8 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_3 PF07726.11 GAX21246.1 - 0.073 12.9 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAX21246.1 - 0.076 13.0 0.0 0.3 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAX21246.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 GAX21246.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAX21246.1 - 0.15 11.8 0.3 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAX21246.1 - 0.39 10.5 5.6 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAX21246.1 - 1.2 9.6 10.7 2 8.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain Fib_alpha PF08702.10 GAX21246.1 - 1.6 8.9 5.5 4.1 7.6 5.5 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SRR1 PF07985.12 GAX21247.1 - 1.9e-11 43.8 0.0 3.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 SRR1 PfUIS3 PF11567.8 GAX21247.1 - 0.018 15.4 0.1 0.03 14.7 0.1 1.3 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein zf-RING_9 PF13901.6 GAX21247.1 - 0.12 12.4 0.3 0.16 11.9 0.3 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon ALAD PF00490.21 GAX21249.1 - 5.1e-141 469.4 0.0 6e-141 469.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase BatA PF07584.11 GAX21250.1 - 0.0085 16.4 2.2 0.031 14.6 0.2 2.4 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal ZapB PF06005.12 GAX21250.1 - 0.072 13.5 0.1 0.072 13.5 0.1 2.2 3 0 0 3 3 3 0 Cell division protein ZapB Voltage_CLC PF00654.20 GAX21250.1 - 0.094 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Glycos_transf_4 PF00953.21 GAX21251.1 - 1.5e-35 122.5 13.0 1.5e-35 122.5 13.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 YfhO PF09586.10 GAX21251.1 - 0.018 13.3 0.4 0.038 12.3 0.4 1.5 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pkinase PF00069.25 GAX21252.1 - 7.8e-41 140.2 0.0 1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21252.1 - 1.4e-21 77.0 0.0 5.2e-21 75.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX21252.1 - 5e-05 23.3 0.4 0.00022 21.2 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX21252.1 - 0.036 12.8 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 GAX21252.1 - 0.041 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 GAX21252.1 - 0.045 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 GAX21252.1 - 0.3 10.0 0.1 0.44 9.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain BolA PF01722.18 GAX21254.1 - 3.4e-13 49.7 0.0 4.9e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein Mg_chelatase PF01078.21 GAX21255.1 - 2.9e-13 49.7 0.6 1.2e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 GAX21255.1 - 7.9e-13 49.0 0.1 3e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_lid_2 PF17863.1 GAX21255.1 - 6.2e-12 45.2 1.9 6.5e-12 45.1 0.2 2.0 2 0 0 2 2 1 1 AAA lid domain VWA PF00092.28 GAX21255.1 - 1.1e-07 32.3 0.0 2.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activat PF00158.26 GAX21255.1 - 1.7e-06 27.8 0.0 0.0068 16.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain MCM PF00493.23 GAX21255.1 - 2.4e-06 26.8 0.0 5.8e-05 22.3 0.0 2.5 2 1 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 GAX21255.1 - 0.00037 20.5 0.1 0.072 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mito_fiss_reg PF05308.11 GAX21255.1 - 0.00093 19.4 3.8 0.0015 18.6 3.8 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator Sigma54_activ_2 PF14532.6 GAX21255.1 - 0.0039 17.3 0.1 1.8 8.7 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 GAX21255.1 - 0.0073 16.7 0.2 0.16 12.3 0.2 2.8 1 1 0 1 1 1 1 AAA ATPase domain VWA_CoxE PF05762.14 GAX21255.1 - 0.024 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CAP_N PF01213.19 GAX21255.1 - 0.035 13.6 5.9 0.057 12.9 5.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_7 PF12775.7 GAX21255.1 - 0.056 13.0 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_Ag35 PF03286.14 GAX21255.1 - 0.12 12.2 4.1 0.27 11.0 4.1 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.13 GAX21255.1 - 0.37 10.6 5.9 1.7 8.5 4.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region PAXIP1_C PF15364.6 GAX21255.1 - 2.5 8.4 14.7 6.9 7.0 14.7 1.7 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein FAM176 PF14851.6 GAX21255.1 - 7.1 6.3 7.0 5.1 6.7 4.9 1.8 2 0 0 2 2 2 0 FAM176 family PTPS PF01242.19 GAX21256.1 - 3.8e-20 72.1 0.0 8.8e-20 70.9 0.0 1.6 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase ATPase-cat_bd PF12156.8 GAX21256.1 - 0.013 16.2 1.6 0.16 12.7 0.3 2.3 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase TPT PF03151.16 GAX21257.1 - 3.4e-56 190.7 14.5 3.8e-56 190.6 14.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX21257.1 - 1.6e-09 38.0 15.3 5.8e-08 33.0 2.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX21257.1 - 0.00073 18.9 9.5 0.0011 18.3 9.5 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 GAX21257.1 - 0.0018 17.6 8.9 0.0022 17.3 8.3 1.5 1 1 0 1 1 1 1 UAA transporter family Chloroa_b-bind PF00504.21 GAX21258.1 - 6e-34 117.9 0.1 8e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein COPI_assoc PF08507.10 GAX21260.1 - 0.00016 21.7 12.2 0.0008 19.5 12.1 1.8 1 1 0 1 1 1 1 COPI associated protein HlyIII PF03006.20 GAX21260.1 - 0.0027 17.5 2.8 0.0038 17.0 2.8 1.3 1 0 0 1 1 1 1 Haemolysin-III related DUF3995 PF13160.6 GAX21260.1 - 0.048 14.0 2.8 0.14 12.5 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) DUF4870 PF09685.10 GAX21260.1 - 3 8.0 10.5 0.4 10.8 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4870) bZIP_1 PF00170.21 GAX21261.1 - 1.6e-09 37.7 10.6 2.8e-09 36.9 10.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX21261.1 - 1.6e-07 31.2 9.9 3e-07 30.4 9.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper MCC-bdg_PDZ PF10506.9 GAX21261.1 - 0.032 14.2 0.9 9.6 6.3 0.0 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_Maf PF03131.17 GAX21261.1 - 0.047 14.2 5.6 0.1 13.1 5.6 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor VWA_2 PF13519.6 GAX21262.1 - 6e-08 33.3 0.2 4.2e-07 30.6 0.0 2.5 4 0 0 4 4 4 1 von Willebrand factor type A domain Het-C PF07217.11 GAX21262.1 - 4.7e-05 22.1 0.0 0.00011 20.9 0.0 1.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C VWA PF00092.28 GAX21262.1 - 9.3e-05 22.7 0.0 0.00039 20.7 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Hydrolase_4 PF12146.8 GAX21263.1 - 7.8e-14 51.5 0.0 1.2e-08 34.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX21263.1 - 1.5e-09 37.9 0.3 2.3e-07 30.7 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX21263.1 - 1.3e-07 31.3 0.0 5.2e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAX21263.1 - 7.4e-07 30.0 0.3 0.00025 21.7 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF818 PF05677.12 GAX21263.1 - 1.9e-06 27.1 0.0 2.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 GAX21263.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAX21263.1 - 0.0043 16.9 0.0 0.031 14.1 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1749 PF08538.10 GAX21263.1 - 0.0057 15.8 0.0 0.0092 15.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) DLH PF01738.18 GAX21263.1 - 0.011 15.2 0.0 0.054 13.0 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 GAX21263.1 - 0.053 13.2 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 GAX21263.1 - 0.16 11.3 0.1 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase Proteasome PF00227.26 GAX21264.1 - 1.8e-42 145.0 0.0 2e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SNF2_N PF00176.23 GAX21265.1 - 2.9e-70 236.7 0.2 2.9e-70 236.7 0.2 3.7 4 0 0 4 4 4 1 SNF2 family N-terminal domain Bromodomain PF00439.25 GAX21265.1 - 1.1e-19 70.3 0.0 3.6e-19 68.6 0.0 2.0 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 GAX21265.1 - 1.6e-18 67.0 0.0 1.6e-18 67.0 0.0 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.6 GAX21265.1 - 0.0018 18.8 0.0 0.0018 18.8 0.0 4.6 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex AhpC-TSA_2 PF13911.6 GAX21266.1 - 1.1e-12 48.0 0.0 1.9e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme RRM_3 PF08777.11 GAX21267.1 - 8.7e-13 48.2 9.4 1.2e-11 44.6 1.6 2.9 2 1 0 2 2 2 2 RNA binding motif La PF05383.17 GAX21267.1 - 1.3e-10 41.1 0.1 2.6e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GAX21267.1 - 9.3e-07 28.6 0.1 7.8e-06 25.6 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSN1_7TM PF02714.15 GAX21268.1 - 1.5e-09 37.5 8.5 1.2e-08 34.6 8.4 2.3 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Anoctamin PF04547.12 GAX21268.1 - 9.8e-05 21.4 3.0 9.8e-05 21.4 3.0 2.1 2 1 0 2 2 2 1 Calcium-activated chloride channel Rsm22 PF09243.10 GAX21269.1 - 1.2e-31 110.0 0.1 3.7e-22 78.9 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 GAX21269.1 - 0.00024 21.0 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAX21269.1 - 0.013 16.5 0.0 0.051 14.6 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain RIG-I_C PF18119.1 GAX21269.1 - 0.016 15.2 0.1 0.051 13.6 0.1 1.8 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain Methyltransf_12 PF08242.12 GAX21269.1 - 0.018 15.7 0.0 0.067 13.9 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Urb2 PF10441.9 GAX21271.1 - 2.8e-15 56.8 3.6 2.8e-15 56.8 3.6 3.9 4 1 0 4 4 4 1 Urb2/Npa2 family Imm8 PF15586.6 GAX21271.1 - 0.14 12.3 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 8 NDK PF00334.19 GAX21272.1 - 4.8e-05 23.4 0.0 0.0097 15.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase TPP_enzyme_N PF02776.18 GAX21273.1 - 2.2e-39 134.8 0.0 5.7e-39 133.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAX21273.1 - 1.8e-34 118.8 0.0 3.7e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAX21273.1 - 6.2e-34 116.7 0.0 1.1e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain RRM_1 PF00076.22 GAX21274.1 - 1.1e-15 57.2 0.1 4.2e-11 42.5 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lyase_1 PF00206.20 GAX21275.1 - 8.2e-21 74.7 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 GAX21275.1 - 2.7e-19 69.5 0.1 1.2e-18 67.4 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HMG_box PF00505.19 GAX21276.1 - 1.6e-17 63.7 0.1 3e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX21276.1 - 1.9e-16 60.4 0.0 5.8e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 GAX21276.1 - 0.36 11.4 2.2 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 YABBY protein M16C_assoc PF08367.11 GAX21277.1 - 2.6e-61 207.0 0.7 3.7e-61 206.4 0.7 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GAX21277.1 - 1.2e-24 87.4 0.0 1.1e-21 77.7 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAX21277.1 - 9.4e-08 32.2 0.2 1e-06 28.8 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) HisK_N PF09385.10 GAX21277.1 - 0.21 11.6 0.3 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Histidine kinase N terminal DUF4423 PF14394.6 GAX21277.1 - 0.35 10.6 2.6 0.28 10.9 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) WHIM1 PF15612.6 GAX21278.1 - 0.22 11.1 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Mor PF08765.11 GAX21278.1 - 1.6 8.8 6.5 0.13 12.3 0.4 2.3 3 0 0 3 3 3 0 Mor transcription activator family DUF4140 PF13600.6 GAX21278.1 - 6.7 7.2 7.5 8.8 6.8 0.4 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) HEAT PF02985.22 GAX21279.1 - 3.2e-29 98.5 38.7 0.0001 22.2 0.1 13.8 14 0 0 14 14 14 7 HEAT repeat HEAT_2 PF13646.6 GAX21279.1 - 2.1e-21 76.1 29.1 2.3e-05 24.7 1.4 7.4 1 1 4 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 GAX21279.1 - 1.8e-13 50.7 14.0 0.0036 17.8 0.1 8.3 7 1 1 8 8 8 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAX21279.1 - 2.4e-12 47.3 2.1 0.012 16.2 0.0 5.9 4 2 2 6 6 6 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAX21279.1 - 1.1e-07 32.1 9.8 0.016 15.3 0.2 5.1 3 3 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAX21279.1 - 0.00073 18.2 1.9 0.0014 17.3 0.6 2.2 3 1 0 3 3 3 1 Adaptin N terminal region Arm PF00514.23 GAX21279.1 - 0.0031 17.5 0.9 19 5.5 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 GAX21279.1 - 0.013 15.1 1.0 2.1 7.9 0.0 3.9 4 1 0 4 4 4 0 CLASP N terminal TetR_C_16 PF17920.1 GAX21279.1 - 0.018 15.3 3.1 0.9 9.8 0.4 4.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CitMHS PF03600.16 GAX21279.1 - 0.026 13.7 0.5 7.4 5.7 0.3 2.6 2 1 1 3 3 3 0 Citrate transporter IFRD PF05004.13 GAX21279.1 - 0.028 13.5 4.5 3.3 6.7 0.0 4.7 3 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Caudo_TAP PF02413.17 GAX21280.1 - 0.19 11.9 2.6 0.43 10.7 0.7 2.3 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK cobW PF02492.19 GAX21281.1 - 2.4e-45 154.3 1.0 3.4e-45 153.8 1.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX21281.1 - 1.2e-19 70.1 0.0 3.8e-19 68.4 0.0 1.9 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 GAX21281.1 - 0.0037 17.2 1.0 0.64 9.9 0.3 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 GAX21281.1 - 0.0046 16.9 0.6 0.61 10.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 GAX21281.1 - 0.015 15.8 0.6 0.041 14.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX21281.1 - 0.025 15.0 0.1 0.063 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 GAX21281.1 - 0.038 14.0 0.1 0.087 12.8 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 GAX21281.1 - 0.039 14.2 0.1 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAX21281.1 - 0.04 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 GAX21281.1 - 0.08 13.4 0.2 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.12 GAX21281.1 - 0.085 11.4 0.3 0.17 10.5 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PIF1 PF05970.14 GAX21281.1 - 0.093 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase T2SSE PF00437.20 GAX21281.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 GAX21281.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 GAX21281.1 - 0.28 10.4 4.6 0.4 9.9 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.25 GAX21282.1 - 5.3e-45 153.8 0.0 5.2e-29 101.4 0.1 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21282.1 - 2.5e-30 105.6 0.0 6.9e-22 78.0 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 GAX21282.1 - 0.01 15.2 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 GAX21282.1 - 0.037 12.8 0.0 0.037 12.8 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 GAX21282.1 - 0.041 13.8 0.4 0.77 9.6 0.5 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Viral_P18 PF04521.13 GAX21282.1 - 0.13 12.0 0.5 0.73 9.6 0.2 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein PRP1_N PF06424.12 GAX21282.1 - 0.43 11.0 4.8 0.46 10.9 0.4 2.5 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Ribosomal_S20p PF01649.18 GAX21282.1 - 0.74 10.5 9.4 0.36 11.5 1.3 2.7 2 0 0 2 2 2 0 Ribosomal protein S20 SepRS_C PF18006.1 GAX21284.1 - 0.42 10.7 5.6 1.3 9.2 0.2 3.7 5 0 0 5 5 5 0 O-phosphoseryl-tRNA synthetase C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 GAX21285.1 - 9.7e-14 52.0 0.0 3.7e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_C1_2 PF03051.15 GAX21285.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family BTB PF00651.31 GAX21286.1 - 6.7e-06 26.3 0.0 1.9e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain HicB_lk_antitox PF15919.5 GAX21286.1 - 0.029 14.5 0.2 0.066 13.3 0.2 1.6 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system ThiF PF00899.21 GAX21287.1 - 1.5e-08 34.3 0.0 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 2 ThiF family SLBP_RNA_bind PF15247.6 GAX21291.1 - 1.5e-22 79.5 1.8 4e-22 78.1 1.8 1.8 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain bZIP_1 PF00170.21 GAX21291.1 - 0.02 15.0 3.1 0.038 14.1 3.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF685 PF05085.12 GAX21291.1 - 0.032 13.6 0.4 0.042 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF685) Ion_trans_2 PF07885.16 GAX21292.1 - 8.5e-29 99.3 22.5 7.9e-16 57.8 11.8 2.3 2 0 0 2 2 2 2 Ion channel EF-hand_6 PF13405.6 GAX21292.1 - 1.9e-07 30.4 0.1 0.0064 16.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAX21292.1 - 2.7e-06 27.7 0.1 0.1 13.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX21292.1 - 3.3e-06 26.3 1.4 0.029 13.9 0.1 2.7 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 GAX21292.1 - 9.6e-06 24.9 1.2 0.022 14.3 0.2 2.5 2 0 0 2 2 2 2 EF hand Ion_trans PF00520.31 GAX21292.1 - 0.00077 18.8 13.4 0.0015 17.8 8.2 2.5 2 0 0 2 2 2 1 Ion transport protein EF-hand_8 PF13833.6 GAX21292.1 - 0.0034 17.2 2.6 0.65 9.9 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 GAX21292.1 - 0.19 12.0 0.9 1.2 9.4 0.8 2.2 1 1 1 2 2 2 0 Dockerin type I domain EMC3_TMCO1 PF01956.16 GAX21292.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.2 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like UPF0242 PF06785.11 GAX21292.1 - 0.32 11.1 2.6 5.3 7.1 0.1 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DIOX_N PF14226.6 GAX21293.1 - 1.8e-25 89.9 0.0 2.6e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAX21293.1 - 1.3e-20 73.8 0.0 2.2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TLD PF07534.16 GAX21294.1 - 1.2e-20 74.2 0.0 2.4e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 TLD Nicastrin PF05450.15 GAX21295.1 - 1.2e-21 77.2 0.2 8.9e-21 74.4 0.2 2.1 1 1 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 GAX21295.1 - 1.7e-14 54.2 0.0 3.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 GAX21295.1 - 1.4e-06 28.1 0.1 5.7e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.25 GAX21296.1 - 3.9e-48 164.1 0.0 2.1e-32 112.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21296.1 - 2e-30 106.0 0.0 8.2e-24 84.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.6 GAX21296.1 - 5.4e-07 29.4 0.5 0.0097 15.5 0.0 2.7 1 1 1 2 2 2 2 PQQ-like domain Kinase-like PF14531.6 GAX21296.1 - 7.3e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PQQ PF01011.21 GAX21296.1 - 0.026 14.5 0.2 8.4 6.5 0.0 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat DUF1971 PF09313.11 GAX21296.1 - 0.049 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Kdo PF06293.14 GAX21296.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.21 GAX21297.1 - 1.3e-24 87.2 0.0 2.5e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DJ-1_PfpI PF01965.24 GAX21298.1 - 5.5e-38 130.4 0.0 6.2e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family UPF0160 PF03690.13 GAX21299.1 - 4.5e-113 378.1 0.0 5.2e-113 377.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rad17 PF03215.15 GAX21300.1 - 3.6e-20 72.7 0.0 6.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 GAX21300.1 - 3.9e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 GAX21300.1 - 0.00037 20.9 1.4 0.0087 16.5 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 GAX21300.1 - 0.0011 19.3 0.0 0.004 17.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAX21300.1 - 0.0016 18.6 0.0 0.0063 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 GAX21300.1 - 0.002 17.6 0.0 0.53 9.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein AAA_22 PF13401.6 GAX21300.1 - 0.0039 17.5 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX21300.1 - 0.02 15.4 0.6 0.068 13.7 0.0 2.2 3 0 0 3 3 2 0 ABC transporter MMR_HSR1 PF01926.23 GAX21300.1 - 0.022 14.8 0.0 0.057 13.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 GAX21300.1 - 0.023 14.0 0.1 0.09 12.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 GAX21300.1 - 0.028 13.6 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 GAX21300.1 - 0.03 14.7 0.4 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 GAX21300.1 - 0.035 13.3 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAX21300.1 - 0.037 13.6 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 GAX21300.1 - 0.046 14.1 0.0 0.29 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAX21300.1 - 0.087 12.7 0.2 0.39 10.6 0.2 2.0 1 1 0 1 1 1 0 NACHT domain Ploopntkinase3 PF18751.1 GAX21300.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 TPR_1 PF00515.28 GAX21301.1 - 1.4e-08 34.2 7.0 0.0022 17.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX21301.1 - 9.2e-07 28.4 2.8 0.0027 17.4 0.2 3.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 GAX21301.1 - 2.4e-06 27.2 18.3 0.014 15.5 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21301.1 - 7.1e-06 26.2 10.6 0.059 13.7 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX21301.1 - 2.4e-05 24.0 0.1 0.074 13.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX21301.1 - 6.4e-05 22.9 14.9 0.043 14.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX21301.1 - 0.00023 21.6 4.3 1.4 9.7 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX21301.1 - 0.0015 19.1 9.7 1 10.3 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 GAX21301.1 - 0.0037 17.3 4.3 2.5 8.2 2.1 3.4 2 1 2 4 4 4 2 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 GAX21301.1 - 0.004 17.8 4.6 0.23 12.1 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX21301.1 - 1.4 9.5 5.7 70 4.0 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX21301.1 - 1.7 8.6 11.5 0.49 10.3 0.2 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.22 GAX21302.1 - 2.3e-76 257.4 0.0 2.8e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAX21303.1 - 2.9e-12 46.2 21.4 2.9e-12 46.2 21.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX21303.1 - 4.4e-06 25.8 13.3 8.8e-06 24.8 13.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltr_RsmB-F PF01189.17 GAX21304.1 - 1.4e-66 224.0 0.0 2.4e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 GAX21304.1 - 3.1e-08 34.0 0.0 7.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 GAX21304.1 - 0.0021 18.2 0.1 0.0036 17.4 0.1 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 GAX21304.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAX21304.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mg_chelatase_C PF13335.6 GAX21304.1 - 0.042 14.5 0.1 0.14 12.8 0.1 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Methyltransf_16 PF10294.9 GAX21305.1 - 1.6e-12 47.5 0.0 1.7e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 GAX21305.1 - 0.026 13.9 0.0 0.079 12.3 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Copine PF07002.16 GAX21306.1 - 2.8e-36 125.0 0.0 5e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX21306.1 - 1.7e-10 41.1 0.0 2.7e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX21306.1 - 0.012 15.7 0.0 0.032 14.4 0.0 1.7 2 0 0 2 2 2 0 vWA found in TerF C terminus Spt20 PF12090.8 GAX21306.1 - 0.41 10.2 7.5 0.74 9.4 7.5 1.4 1 0 0 1 1 1 0 Spt20 family Copine PF07002.16 GAX21307.1 - 2.5e-49 167.7 0.0 3.4e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX21307.1 - 1.1e-18 67.4 0.0 1.1e-08 35.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX21307.1 - 8.7e-05 22.7 0.0 0.00021 21.5 0.0 1.6 1 1 0 1 1 1 1 vWA found in TerF C terminus WD40 PF00400.32 GAX21308.1 - 1.4e-35 120.7 35.1 2.6e-07 31.2 0.0 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.12 GAX21308.1 - 4e-07 30.3 0.5 8e-07 29.3 0.5 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 GAX21308.1 - 0.012 14.3 3.1 4.6 5.8 0.0 4.2 4 1 0 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 GAX21308.1 - 0.13 11.6 0.2 0.75 9.1 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain Hira PF07569.11 GAX21308.1 - 0.26 11.0 0.8 3.7 7.2 0.2 3.0 3 0 0 3 3 3 0 TUP1-like enhancer of split PTPA PF03095.15 GAX21310.1 - 2.8e-92 309.4 0.0 3.3e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DNA_topoisoIV PF00521.20 GAX21313.1 - 6.1e-109 364.7 0.0 8.8e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAX21313.1 - 7e-38 129.8 0.1 1.3e-37 128.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAX21313.1 - 5.7e-14 52.0 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GAX21313.1 - 6.7e-10 39.5 0.0 1.5e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAX21313.1 - 7.4e-07 29.3 0.0 1.9e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain FTCD PF02971.14 GAX21314.1 - 0.071 13.2 0.1 0.083 12.9 0.1 1.2 1 0 0 1 1 1 0 Formiminotransferase domain CbiG_mid PF11761.8 GAX21314.1 - 0.089 12.9 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis central region Gly-zipper_OmpA PF13436.6 GAX21315.1 - 3.2e-11 42.8 21.0 3.2e-11 42.8 21.0 2.0 2 0 0 2 2 2 1 Glycine-zipper domain SAM_1 PF00536.30 GAX21315.1 - 1.2e-08 35.3 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Gly-zipper_YMGG PF13441.6 GAX21315.1 - 2.1e-08 33.8 23.1 2.1e-08 33.8 23.1 2.2 2 0 0 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 GAX21315.1 - 7.3e-06 25.9 21.2 7.3e-06 25.9 21.2 2.2 2 0 0 2 2 2 1 Glycine zipper SAM_2 PF07647.17 GAX21315.1 - 2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1269 PF06897.12 GAX21315.1 - 0.0069 16.6 7.3 0.014 15.7 7.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) Romo1 PF10247.9 GAX21315.1 - 0.037 14.4 5.1 1.4 9.3 1.3 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 bZIP_1 PF00170.21 GAX21315.1 - 0.046 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor SOGA PF11365.8 GAX21315.1 - 0.15 13.2 0.0 0.22 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein SOGA EII-Sor PF03609.14 GAX21315.1 - 0.29 10.5 2.9 0.41 10.0 2.9 1.1 1 0 0 1 1 1 0 PTS system sorbose-specific iic component SAP PF02037.27 GAX21316.1 - 0.13 12.0 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 SAP domain MAP70 PF07058.11 GAX21317.1 - 4.1 6.0 9.5 7.4 5.2 9.5 1.3 1 0 0 1 1 1 0 Microtubule-associated protein 70 GFO_IDH_MocA PF01408.22 GAX21318.1 - 0.025 15.4 0.0 0.067 14.0 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DEAD PF00270.29 GAX21319.1 - 5.1e-39 133.8 0.3 1.1e-38 132.7 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX21319.1 - 5.1e-20 71.9 0.0 2.1e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX21319.1 - 0.005 16.9 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Asp_Arg_Hydrox PF05118.15 GAX21321.1 - 2.4e-28 98.9 0.1 5.6e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Prefoldin_2 PF01920.20 GAX21322.1 - 0.071 13.1 0.4 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Prefoldin subunit T2SSK PF03934.13 GAX21322.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Pkinase PF00069.25 GAX21323.1 - 1.7e-38 132.5 0.0 2.5e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21323.1 - 4.5e-20 72.0 0.0 3.3e-19 69.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX21323.1 - 5.3e-07 29.8 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX21323.1 - 0.0067 15.8 0.0 0.018 14.4 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX21323.1 - 0.018 14.3 0.1 0.31 10.3 0.0 2.5 2 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 GAX21323.1 - 0.038 12.8 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 GAX21323.1 - 0.039 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 GAX21323.1 - 0.079 12.5 2.8 0.19 11.3 2.8 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 GAX21323.1 - 0.12 11.6 0.1 0.24 10.7 0.1 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase SOUL PF04832.12 GAX21324.1 - 5.9e-44 150.2 0.4 1.3e-43 149.1 0.4 1.6 1 0 0 1 1 1 1 SOUL heme-binding protein Bap31_Bap29_C PF18035.1 GAX21324.1 - 0.058 13.4 0.8 0.058 13.4 0.8 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain SPOR PF05036.13 GAX21324.1 - 0.062 13.7 0.4 0.72 10.3 0.0 2.4 2 0 0 2 2 2 0 Sporulation related domain DUF4806 PF16064.5 GAX21324.1 - 0.062 13.6 0.1 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) Rnk_N PF14760.6 GAX21324.1 - 0.094 13.2 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Rnk N-terminus RuvX PF03652.15 GAX21325.1 - 2e-22 80.0 3.1 1.6e-21 77.1 0.0 2.8 3 0 0 3 3 3 1 Holliday junction resolvase Tombus_P19 PF03220.13 GAX21325.1 - 0.047 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Tombusvirus P19 core protein Trypsin_2 PF13365.6 GAX21326.1 - 0.12 13.2 0.0 0.26 12.2 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain adh_short PF00106.25 GAX21327.1 - 2.7e-26 92.3 0.1 4.5e-25 88.2 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX21327.1 - 4.8e-15 55.8 0.0 3.9e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX21327.1 - 3.5e-08 33.6 0.2 5.5e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX21327.1 - 0.02 14.4 0.3 0.029 13.8 0.3 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX21327.1 - 0.021 14.3 0.2 0.11 11.9 0.2 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAX21327.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family DUF4079 PF13301.6 GAX21328.1 - 1.4e-20 73.8 7.6 1.8e-20 73.5 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 GAX21328.1 - 0.00013 21.6 6.6 0.0033 17.0 1.6 2.1 1 1 1 2 2 2 2 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 GAX21328.1 - 0.21 11.7 6.8 2.7 8.1 0.5 2.6 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 SpoIIM PF01944.17 GAX21328.1 - 0.35 10.9 4.8 0.85 9.6 0.3 2.3 1 1 1 2 2 2 0 Stage II sporulation protein M DUF4405 PF14358.6 GAX21328.1 - 3.4 8.3 11.0 1.4 9.5 3.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4405) EMP70 PF02990.16 GAX21329.1 - 8.1e-157 523.0 7.1 1.2e-156 522.5 7.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Tocopherol_cycl PF14249.6 GAX21330.1 - 1.3e-120 402.6 3.7 1.6e-120 402.3 3.7 1.0 1 0 0 1 1 1 1 Tocopherol cyclase RNA_pol_3_Rpc31 PF11705.8 GAX21331.1 - 0.00016 22.0 0.1 0.0003 21.1 0.1 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2939 PF11159.8 GAX21331.1 - 0.11 12.9 0.2 2.9 8.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) MFS_1 PF07690.16 GAX21332.1 - 4.7e-25 88.3 23.6 6.2e-25 87.9 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX21332.1 - 1.3e-07 30.9 5.8 1.3e-07 30.9 5.8 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter ZYG-11_interact PF05884.12 GAX21332.1 - 0.00078 18.9 0.5 0.00078 18.9 0.5 1.8 2 0 0 2 2 2 1 Interactor of ZYG-11 Elong_Iki1 PF10483.9 GAX21333.1 - 0.0003 20.4 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 ELP6 PF09807.9 GAX21333.1 - 0.0097 15.3 0.0 0.028 13.8 0.0 1.7 2 1 0 2 2 2 1 Elongation complex protein 6 SUIM_assoc PF16619.5 GAX21333.1 - 0.11 12.6 7.5 0.26 11.4 7.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 IF4E PF01652.18 GAX21334.1 - 7.3e-49 165.6 1.8 8.7e-49 165.4 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_M48 PF01435.18 GAX21335.1 - 1.2e-34 119.8 0.1 2.2e-34 119.0 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M48 RuvA_N PF01330.21 GAX21335.1 - 0.042 14.0 0.0 0.58 10.3 0.0 2.3 2 0 0 2 2 2 0 RuvA N terminal domain Polysacc_deac_3 PF15421.6 GAX21335.1 - 0.13 10.7 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase Beach PF02138.18 GAX21336.1 - 6.4e-103 343.9 0.0 8.8e-103 343.5 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAX21336.1 - 2.1e-09 37.4 0.0 7.7e-05 22.7 0.0 3.6 2 1 1 3 3 3 2 PH domain associated with Beige/BEACH WD40 PF00400.32 GAX21336.1 - 0.00043 21.0 13.9 0.068 14.1 0.5 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat GRAM PF02893.20 GAX21336.1 - 0.0059 16.5 0.0 0.67 9.9 0.0 2.6 2 0 0 2 2 2 1 GRAM domain BIR PF00653.21 GAX21336.1 - 0.054 14.1 0.1 0.15 12.7 0.1 1.7 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain Methyltransf_4 PF02390.17 GAX21338.1 - 7.3e-25 87.4 0.0 2.1e-23 82.7 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAX21338.1 - 0.092 13.5 0.1 0.58 10.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF1445 PF07286.12 GAX21339.1 - 1.9e-57 193.2 0.0 2.9e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) NRD1_2 PF01995.16 GAX21339.1 - 2.7e-05 23.6 0.0 0.008 15.5 0.0 2.8 2 1 0 2 2 2 2 NrpR regulatory domains NRD1 and 2 Polyketide_cyc PF03364.20 GAX21341.1 - 1.2e-14 54.7 0.0 2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAX21341.1 - 2.6e-06 27.8 0.0 4.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3689 PF12463.8 GAX21342.1 - 7.5e-68 229.1 2.7 1.7e-51 175.4 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3689) ABC1 PF03109.16 GAX21344.1 - 3.2e-20 72.5 0.0 8.3e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.17 GAX21344.1 - 2.2e-08 33.7 0.0 0.00094 18.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 GAX21344.1 - 0.00019 21.1 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 GAX21344.1 - 0.0002 20.8 0.0 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GAX21344.1 - 0.021 14.7 0.1 0.06 13.3 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 GAX21344.1 - 0.037 13.2 0.0 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase Glyoxalase PF00903.25 GAX21345.1 - 7.1e-08 32.7 0.0 9.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TAL_FSA PF00923.19 GAX21346.1 - 1.7e-76 257.3 0.0 2e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF3493 PF11998.8 GAX21347.1 - 1.4e-23 82.8 0.1 2.7e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 HLH PF00010.26 GAX21349.1 - 9.6e-09 35.1 2.6 1.2e-08 34.8 0.3 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 GAX21349.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 GAX21349.1 - 0.1 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain CDC45 PF02724.14 GAX21349.1 - 2.3 6.4 5.9 3 6.0 4.9 1.6 2 0 0 2 2 2 0 CDC45-like protein ERO1 PF04137.15 GAX21350.1 - 1.6e-48 165.7 1.1 2.3e-47 161.9 1.1 2.0 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Mg296 PF09644.10 GAX21350.1 - 0.11 12.7 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Mg296 protein Hexapep PF00132.24 GAX21351.1 - 6.6e-13 47.8 14.6 3e-05 23.6 0.4 4.5 3 1 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAX21351.1 - 0.00012 21.7 9.5 0.0094 15.7 1.3 3.7 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Imm70 PF15601.6 GAX21351.1 - 0.047 13.2 0.0 0.19 11.3 0.0 1.9 1 1 1 2 2 2 0 Immunity protein 70 DUF4954 PF16314.5 GAX21351.1 - 0.11 10.5 0.5 0.16 10.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CKS PF01111.19 GAX21352.1 - 2.3e-35 120.7 0.6 2.9e-35 120.3 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit His_Phos_1 PF00300.22 GAX21353.1 - 0.0072 16.0 0.1 0.31 10.7 0.0 2.8 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) DUF2140 PF09911.9 GAX21355.1 - 0.17 11.4 0.0 23 4.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Methyltransf_16 PF10294.9 GAX21357.1 - 8.4e-27 94.0 0.1 1.8e-26 92.9 0.1 1.5 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX21357.1 - 3.5e-06 26.7 0.0 6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX21357.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 GAX21357.1 - 0.0012 19.6 0.2 0.0031 18.2 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX21357.1 - 0.0032 17.3 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX21357.1 - 0.0053 16.5 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GAX21357.1 - 0.023 15.4 0.4 0.26 12.0 0.2 2.6 1 1 1 2 2 2 0 Methyltransferase domain Ribosomal_S7e PF01251.18 GAX21358.1 - 1.3e-69 233.6 0.2 1.5e-69 233.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DNA_pol_E_B PF04042.16 GAX21359.1 - 1.5e-36 125.8 0.7 2.5e-36 125.0 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 GAX21359.1 - 3.3e-06 27.3 1.0 5.9e-06 26.4 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.6 GAX21359.1 - 0.2 11.0 0.0 10 5.3 0.0 2.1 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily TruB_N PF01509.18 GAX21360.1 - 8.9e-47 159.2 0.0 1.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAX21360.1 - 5e-06 26.6 0.0 1.5e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Ank_2 PF12796.7 GAX21361.1 - 2.3e-62 207.6 16.6 7.2e-17 61.8 0.1 5.5 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX21361.1 - 4.3e-42 137.3 4.8 5.3e-05 23.3 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 GAX21361.1 - 4.8e-40 135.4 4.7 9.9e-09 35.6 0.0 7.6 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 GAX21361.1 - 9.1e-35 117.6 9.6 0.00011 22.4 0.1 8.4 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 GAX21361.1 - 4.5e-32 109.7 8.5 2.1e-07 31.1 0.0 8.0 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Cation_ATPase_N PF00690.26 GAX21361.1 - 0.027 14.1 0.0 0.099 12.3 0.0 1.9 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus PhyH PF05721.13 GAX21362.1 - 2.6e-09 37.6 2.4 2.7e-09 37.6 0.2 2.1 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) SMC_N PF02463.19 GAX21363.1 - 1e-65 221.3 16.7 3e-64 216.5 16.7 3.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAX21363.1 - 1.5e-21 76.8 0.7 4.4e-21 75.4 0.7 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAX21363.1 - 5.1e-10 39.6 7.1 4.7e-05 23.3 0.7 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAX21363.1 - 1.7e-05 25.4 34.5 1.7e-05 25.4 34.5 6.5 2 2 0 2 2 2 1 AAA domain FPP PF05911.11 GAX21363.1 - 4.9e-05 21.7 26.2 4.9e-05 21.7 26.2 3.8 3 1 1 4 4 4 2 Filament-like plant protein, long coiled-coil AAA_29 PF13555.6 GAX21363.1 - 7.2e-05 22.4 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX21363.1 - 0.01 16.3 0.0 0.01 16.3 0.0 5.7 4 2 0 4 4 4 0 ABC transporter CooC_C PF15976.5 GAX21363.1 - 0.028 14.5 0.9 0.15 12.1 0.2 2.7 3 0 0 3 3 3 0 CS1-pili formation C-terminal LacI PF00356.21 GAX21363.1 - 0.053 13.3 1.7 3.5 7.5 0.1 3.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family BATS PF06968.13 GAX21365.1 - 2.7e-18 65.9 0.0 7.2e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 GAX21365.1 - 5e-13 49.8 0.1 8.1e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Peptidase_M24 PF00557.24 GAX21365.1 - 0.0055 16.4 0.1 0.0083 15.8 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Transcrip_reg PF01709.20 GAX21366.1 - 8.4e-67 225.1 3.2 1e-66 224.8 3.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator Thioredoxin_6 PF13848.6 GAX21366.1 - 0.062 13.2 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain p450 PF00067.22 GAX21367.1 - 9.7e-07 27.9 0.0 1.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L12 PF00542.19 GAX21367.1 - 0.12 12.8 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Ribosomal_S17 PF00366.20 GAX21368.1 - 8e-22 77.1 0.7 1.2e-21 76.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 RVT_2 PF07727.14 GAX21369.1 - 6.6e-38 130.7 0.0 1.3e-37 129.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX21369.1 - 0.001 19.2 0.3 0.0029 17.8 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 GAX21369.1 - 0.02 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain zf-CCHC PF00098.23 GAX21370.1 - 2e-07 30.8 5.0 4e-07 29.8 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GAX21370.1 - 0.042 13.8 1.9 0.083 12.9 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3558 PF12079.8 GAX21372.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) IF3_C PF00707.22 GAX21375.1 - 4.8e-10 39.3 1.2 5.6e-08 32.6 0.3 3.3 3 1 1 4 4 4 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 GAX21375.1 - 2e-08 34.4 0.1 3.6e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain cwf18 PF08315.12 GAX21375.1 - 0.086 13.5 3.9 0.18 12.4 3.9 1.6 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor YwqJ-deaminase PF14431.6 GAX21376.1 - 0.086 13.0 0.3 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 YwqJ-like deaminase zf-CCHC PF00098.23 GAX21376.1 - 0.2 11.8 4.0 0.35 11.0 4.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Fasciclin PF02469.22 GAX21379.1 - 5.2e-44 149.6 4.2 2.9e-14 53.4 0.5 4.2 4 0 0 4 4 4 4 Fasciclin domain Dehydratase_hem PF13816.6 GAX21379.1 - 0.055 12.9 0.6 0.088 12.2 0.6 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase Ank_2 PF12796.7 GAX21380.1 - 5.9e-23 81.3 0.0 6.3e-09 36.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX21380.1 - 1.7e-16 60.0 2.0 9.8e-05 22.6 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21380.1 - 1.1e-14 53.0 3.7 0.071 13.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 GAX21380.1 - 1.7e-09 38.1 0.3 7.2e-06 26.4 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX21380.1 - 9.1e-08 32.2 4.5 0.31 11.6 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat PBP_like_2 PF12849.7 GAX21381.1 - 1.7e-31 110.0 1.0 2.5e-31 109.4 0.1 1.6 2 0 0 2 2 2 1 PBP superfamily domain DUF1515 PF07439.11 GAX21381.1 - 0.011 15.7 3.1 1.7 8.7 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) ABC_tran_CTD PF16326.5 GAX21381.1 - 0.019 15.2 0.3 0.056 13.7 0.3 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain GET2 PF08690.10 GAX21381.1 - 0.032 13.9 0.9 0.047 13.4 0.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 CENP-F_leu_zip PF10473.9 GAX21381.1 - 0.11 12.5 0.9 0.19 11.7 0.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 GAX21381.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Fasciclin PF02469.22 GAX21382.1 - 5e-41 139.9 2.7 8.9e-20 71.2 0.2 2.7 3 0 0 3 3 3 2 Fasciclin domain Chalcone PF02431.15 GAX21382.1 - 0.035 13.5 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Chalcone-flavanone isomerase Fasciclin PF02469.22 GAX21384.1 - 5.8e-37 126.8 0.1 4.2e-24 85.2 0.1 2.6 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 GAX21386.1 - 6.4e-47 159.0 0.1 3.6e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain MSP1_C PF07462.11 GAX21386.1 - 8.6 4.9 6.7 12 4.4 6.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Fasciclin PF02469.22 GAX21387.1 - 4.3e-30 104.6 0.0 4.2e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 GAX21388.1 - 4e-66 221.1 0.0 6.6e-16 58.7 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain HMD PF03201.16 GAX21388.1 - 0.76 10.0 4.9 2.1 8.7 0.1 3.6 4 0 0 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Fasciclin PF02469.22 GAX21389.1 - 2.5e-27 95.6 0.0 8.2e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain SAP25 PF15476.6 GAX21393.1 - 0.003 17.2 0.2 0.0049 16.6 0.2 1.3 1 0 0 1 1 1 1 Histone deacetylase complex subunit SAP25 BPL_C PF02237.17 GAX21393.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain PT PF04886.12 GAX21395.1 - 0.0099 15.4 4.2 0.0099 15.4 4.2 1.9 2 0 0 2 2 2 1 PT repeat Conotoxin_I2 PF17557.2 GAX21395.1 - 0.091 12.9 7.6 0.37 10.9 7.6 2.1 1 0 0 1 1 1 0 I2-superfamily conotoxins HAD_2 PF13419.6 GAX21400.1 - 1.2e-12 48.3 0.0 2.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX21400.1 - 9.8e-11 42.3 0.0 9.7e-10 39.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX21400.1 - 2e-09 37.4 0.0 4.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GAX21400.1 - 3.9e-06 27.4 0.1 5.8e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Gly_reductase PF09338.11 GAX21400.1 - 0.081 11.3 0.2 0.12 10.8 0.2 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits Acid_PPase PF12689.7 GAX21400.1 - 0.49 10.2 3.4 1.3 8.8 0.0 2.4 1 1 0 2 2 2 0 Acid Phosphatase RVT_2 PF07727.14 GAX21402.1 - 1.5e-16 60.8 0.0 8.4e-16 58.3 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acetyltransf_7 PF13508.7 GAX21406.1 - 0.0027 18.1 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX21406.1 - 0.081 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family LAP1C PF05609.12 GAX21407.1 - 0.0062 15.7 6.5 0.0071 15.5 6.5 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Pacs-1 PF10254.9 GAX21407.1 - 0.073 12.0 5.3 0.097 11.6 5.3 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein DOT1 PF08123.13 GAX21408.1 - 4.9e-11 42.6 0.0 9.6e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Histone methylation protein DOT1 EF-hand_1 PF00036.32 GAX21409.1 - 3.8e-22 76.1 4.7 8.7e-11 40.6 1.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAX21409.1 - 6.9e-19 68.1 1.3 8.4e-19 67.8 1.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX21409.1 - 1e-18 66.9 5.1 4.2e-17 61.7 0.9 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX21409.1 - 2.4e-15 55.1 1.2 2.3e-09 36.4 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX21409.1 - 4.7e-14 51.2 1.9 1.1e-06 27.8 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 GAX21409.1 - 1.9e-05 24.5 0.3 2.3e-05 24.3 0.3 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 GAX21409.1 - 2.5e-05 25.1 0.0 2.5e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain EFhand_Ca_insen PF08726.10 GAX21409.1 - 3.4e-05 23.9 0.2 5.8e-05 23.1 0.2 1.5 1 1 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.6 GAX21409.1 - 4.5e-05 23.7 0.0 5.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GAX21409.1 - 0.00034 20.9 0.1 0.00039 20.7 0.1 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GAX21409.1 - 0.0044 17.2 0.3 0.0094 16.1 0.3 1.5 1 1 1 2 2 2 1 Dockerin type I domain UPF0154 PF03672.13 GAX21409.1 - 0.072 13.1 0.3 0.51 10.4 0.0 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF5580 PF17743.1 GAX21409.1 - 0.097 11.2 0.0 0.097 11.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) MotA_activ PF09114.10 GAX21409.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription factor MotA, activation domain PseudoU_synth_1 PF01416.20 GAX21410.1 - 1e-17 64.5 0.0 1.6e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 tRNA pseudouridine synthase TMEM51 PF15345.6 GAX21411.1 - 0.081 12.8 5.3 0.15 11.9 5.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 PROL5-SMR PF15621.6 GAX21411.1 - 3.4 8.3 16.5 2.6 8.6 8.9 2.5 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Transglut_core PF01841.19 GAX21413.1 - 2.1e-12 47.5 2.7 2.9e-12 47.0 0.8 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.12 GAX21413.1 - 0.0057 16.2 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like domain RRM_1 PF00076.22 GAX21414.1 - 1.2e-20 73.0 0.1 3.9e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_4 PF13717.6 GAX21414.1 - 1.6e-05 24.7 0.5 3e-05 23.8 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.6 GAX21414.1 - 0.0092 15.7 1.8 0.012 15.3 0.2 2.0 2 0 0 2 2 2 1 zinc-ribbon domain zf-CSL PF05207.13 GAX21414.1 - 0.09 12.5 1.1 0.24 11.1 0.6 2.0 2 0 0 2 2 2 0 CSL zinc finger zinc_ribbon_12 PF11331.8 GAX21414.1 - 0.54 10.1 5.4 1.3 8.9 0.5 2.6 2 1 1 3 3 3 0 Probable zinc-ribbon domain RNA_POL_M_15KD PF02150.16 GAX21414.1 - 3 7.8 5.1 5.1 7.1 0.1 2.6 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit GLTP PF08718.11 GAX21415.1 - 0.12 12.7 1.1 29 4.9 0.0 4.1 4 0 0 4 4 4 0 Glycolipid transfer protein (GLTP) TAF6_C PF07571.13 GAX21415.1 - 0.21 11.9 0.9 6.7 7.1 0.1 3.5 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain RRN3 PF05327.11 GAX21415.1 - 0.45 9.0 7.4 0.1 11.1 0.6 2.7 2 2 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Endonuc-BsobI PF09194.10 GAX21416.1 - 0.089 12.0 0.4 0.43 9.7 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease BsobI TPR_1 PF00515.28 GAX21416.1 - 0.22 11.4 0.3 4.5 7.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HMG_box PF00505.19 GAX21417.1 - 3.4e-31 107.5 21.4 1.5e-18 66.9 5.1 2.7 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX21417.1 - 2.1e-23 82.7 18.1 6.6e-12 45.9 5.9 2.5 2 0 0 2 2 2 2 HMG-box domain Sec10 PF07393.11 GAX21417.1 - 0.1 11.0 0.2 0.17 10.3 0.2 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec10 CinA PF02464.17 GAX21417.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Competence-damaged protein MATalpha_HMGbox PF04769.12 GAX21417.1 - 0.13 11.5 1.4 0.22 10.8 1.4 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box VitD-bind_III PF09164.10 GAX21417.1 - 0.18 11.9 0.8 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Condensin2nSMC PF12422.8 GAX21417.1 - 0.24 11.6 0.7 4 7.6 0.1 2.1 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit RNase_PH PF01138.21 GAX21418.1 - 1e-06 29.3 0.0 3.7e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX21418.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 AAA PF00004.29 GAX21419.1 - 4.1e-41 140.5 0.0 6.6e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 GAX21419.1 - 8.6e-19 67.4 4.7 8.6e-19 67.4 4.7 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 GAX21419.1 - 4e-16 58.7 0.0 1.5e-15 57.0 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 GAX21419.1 - 4.3e-07 30.3 0.2 0.017 15.4 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_lid_3 PF17862.1 GAX21419.1 - 5.7e-07 29.2 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX21419.1 - 2.5e-05 24.7 0.1 0.00011 22.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAX21419.1 - 3.4e-05 23.7 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 GAX21419.1 - 8.4e-05 22.4 0.1 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX21419.1 - 0.00014 21.9 0.1 0.0012 18.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX21419.1 - 0.00014 21.1 0.0 0.00034 19.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 GAX21419.1 - 0.00017 21.7 0.0 0.00045 20.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 GAX21419.1 - 0.00022 21.3 0.0 0.00059 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAX21419.1 - 0.00027 20.7 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 GAX21419.1 - 0.0025 17.6 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 GAX21419.1 - 0.0026 17.9 0.0 0.0069 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX21419.1 - 0.0026 18.3 0.0 0.008 16.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 GAX21419.1 - 0.0078 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 GAX21419.1 - 0.0091 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.26 GAX21419.1 - 0.02 14.6 0.0 0.13 12.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 GAX21419.1 - 0.034 14.6 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAX21419.1 - 0.036 13.4 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX21419.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 GAX21419.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 GAX21419.1 - 0.072 12.7 0.2 0.71 9.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain Zn_ribbon_SprT PF17283.2 GAX21419.1 - 0.095 12.6 1.9 0.28 11.1 1.9 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain AFG1_ATPase PF03969.16 GAX21419.1 - 0.097 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase PhoH PF02562.16 GAX21419.1 - 0.11 12.0 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 GAX21419.1 - 0.11 12.4 0.0 0.85 9.5 0.0 2.1 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 GAX21419.1 - 0.11 12.4 0.0 3.1 7.6 0.0 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TPR_1 PF00515.28 GAX21419.1 - 0.16 11.9 0.7 0.42 10.5 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat KAP_NTPase PF07693.14 GAX21419.1 - 0.18 11.0 0.0 2.7 7.1 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain TPR_7 PF13176.6 GAX21419.1 - 0.54 10.4 1.9 0.93 9.7 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21419.1 - 0.62 10.3 2.9 0.49 10.6 0.3 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat WW PF00397.26 GAX21420.1 - 2.7e-21 75.3 6.1 2.5e-11 43.5 0.3 2.5 2 0 0 2 2 2 2 WW domain FYVE PF01363.21 GAX21420.1 - 1.3e-16 60.5 7.4 1.3e-16 60.5 7.4 2.3 3 0 0 3 3 3 1 FYVE zinc finger Adaptin_N PF01602.20 GAX21420.1 - 0.0087 14.7 6.7 0.63 8.5 0.0 3.6 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 GAX21420.1 - 0.08 13.5 28.8 3.4 8.3 0.1 8.5 7 1 0 7 7 7 0 HEAT-like repeat HEAT PF02985.22 GAX21420.1 - 0.29 11.5 11.0 27 5.4 0.0 8.0 7 0 0 7 7 7 0 HEAT repeat HSF_DNA-bind PF00447.17 GAX21421.1 - 1.5e-15 57.6 0.0 2.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding p450 PF00067.22 GAX21422.1 - 1.6e-77 261.2 0.0 2.7e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DnaGprimase_HBD PF16730.5 GAX21422.1 - 0.035 14.2 0.8 0.063 13.4 0.3 1.6 2 0 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain Cnl2_NKP2 PF09447.10 GAX21422.1 - 0.1 12.8 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 Cnl2/NKP2 family protein FAST_1 PF06743.15 GAX21423.1 - 0.0024 17.8 0.1 0.58 10.1 0.0 4.1 3 1 1 4 4 4 1 FAST kinase-like protein, subdomain 1 RdRP_1 PF00680.20 GAX21423.1 - 0.22 10.0 0.5 2.8 6.4 0.0 2.4 3 0 0 3 3 3 0 RNA dependent RNA polymerase Pro_isomerase PF00160.21 GAX21424.1 - 3.3e-14 53.4 0.0 7.8e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FlgN PF05130.12 GAX21424.1 - 0.067 13.7 0.3 0.14 12.7 0.3 1.5 1 0 0 1 1 1 0 FlgN protein Mito_carr PF00153.27 GAX21425.1 - 3.6e-19 68.5 1.9 6e-07 29.3 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DEK_C PF08766.11 GAX21426.1 - 0.0078 16.1 0.2 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 DEK C terminal domain Ribosomal_L7Ae PF01248.26 GAX21426.1 - 0.019 14.7 0.1 0.66 9.7 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family THF_DHG_CYH PF00763.23 GAX21428.1 - 3.4e-14 53.1 0.0 5.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAX21428.1 - 4.6e-11 42.3 0.3 4.3e-09 35.9 0.3 3.4 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CMD PF02627.20 GAX21429.1 - 0.00018 21.5 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family NUC173 PF08161.12 GAX21429.1 - 0.00049 19.8 0.0 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 NUC173 domain CTD_bind PF04818.13 GAX21430.1 - 4.6e-15 56.2 0.0 2.4e-14 53.9 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase II-binding domain. BAG PF02179.16 GAX21430.1 - 0.018 15.5 2.8 0.078 13.4 2.8 2.3 1 1 0 1 1 1 0 BAG domain MSP1a PF11670.8 GAX21430.1 - 0.76 9.0 2.0 1.5 8.1 2.0 1.4 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) baeRF_family10 PF18854.1 GAX21431.1 - 0.035 14.4 0.0 0.04 14.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 TraL PF07178.11 GAX21431.1 - 0.26 11.8 0.3 1.1 9.8 0.0 1.9 2 0 0 2 2 2 0 TraL protein TYW3 PF02676.14 GAX21432.1 - 4.7e-39 134.0 0.0 7.9e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.16 GAX21432.1 - 7.8e-21 74.7 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTP18 PF10558.9 GAX21433.1 - 2.2e-16 60.3 2.5 1e-14 54.9 2.5 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) CENP-N PF05238.13 GAX21434.1 - 3.7e-08 33.1 0.5 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Kinetochore protein CHL4 like HATPase_c PF02518.26 GAX21436.1 - 1.5e-20 73.8 0.0 3.7e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX21436.1 - 2.4e-20 72.8 0.2 5.3e-20 71.7 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX21436.1 - 1.4e-15 57.0 0.7 5.1e-15 55.3 0.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX21436.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Erp_C PF06780.11 GAX21436.1 - 0.11 12.5 0.4 0.27 11.3 0.4 1.7 1 0 0 1 1 1 0 Erp protein C-terminus CENP-X PF09415.10 GAX21436.1 - 0.15 12.4 0.6 0.57 10.5 0.1 2.4 3 0 0 3 3 3 0 CENP-S associating Centromere protein X ABC2_membrane_2 PF12679.7 GAX21436.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC1 PF03109.16 GAX21437.1 - 4.1e-31 107.6 0.0 8.7e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX21437.1 - 2.2e-06 27.8 0.0 7e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX21437.1 - 3.7e-05 23.2 0.0 0.001 18.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Glyco_transf_10 PF00852.19 GAX21438.1 - 8.3e-33 113.6 0.0 1.6e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Ank_2 PF12796.7 GAX21439.1 - 1.1e-13 51.5 1.1 2e-07 31.5 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX21439.1 - 6.4e-12 45.7 0.4 9.8e-07 29.2 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21439.1 - 7.6e-05 22.8 0.0 0.00035 20.8 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 GAX21439.1 - 0.00024 21.3 0.0 0.00093 19.5 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX21439.1 - 0.0015 18.9 0.0 0.033 14.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Shigella_OspC PF06128.11 GAX21439.1 - 0.043 13.5 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Shigella flexneri OspC protein WD40 PF00400.32 GAX21441.1 - 0.021 15.7 2.6 15 6.7 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat WD40_like PF17005.5 GAX21441.1 - 0.042 13.2 0.2 0.18 11.1 0.1 2.0 2 1 1 3 3 3 0 WD40-like domain PT PF04886.12 GAX21442.1 - 0.12 12.0 0.2 0.12 12.0 0.2 5.4 6 1 1 7 7 7 0 PT repeat Pkinase PF00069.25 GAX21443.1 - 5.3e-31 107.9 0.0 1.4e-30 106.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21443.1 - 3e-30 105.4 0.0 1.1e-29 103.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX21443.1 - 0.0024 16.7 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX21443.1 - 0.0038 17.2 2.3 0.011 15.7 2.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3042 PF11240.8 GAX21443.1 - 0.063 13.3 1.3 0.83 9.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Thymidylate_kin PF02223.17 GAX21444.1 - 3.3e-46 157.3 0.0 4e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 GAX21444.1 - 0.027 15.0 0.1 0.084 13.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 GAX21444.1 - 0.035 14.1 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAX21444.1 - 0.058 13.8 0.0 0.94 9.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX21444.1 - 0.078 13.3 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX21444.1 - 0.081 13.3 0.2 0.11 12.9 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 GAX21444.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2524 PF10732.9 GAX21444.1 - 0.2 12.0 4.5 0.28 11.5 2.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Gtr1_RagA PF04670.12 GAX21445.1 - 1.1e-91 306.3 0.0 1.4e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAX21445.1 - 8.6e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAX21445.1 - 2.6e-07 30.4 0.0 5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX21445.1 - 3.9e-07 30.3 0.0 1.2e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAX21445.1 - 0.00065 19.8 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAX21445.1 - 0.072 12.2 2.5 2.3 7.3 0.0 2.8 1 1 2 3 3 3 0 G-protein alpha subunit SRPRB PF09439.10 GAX21445.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 GAX21445.1 - 0.2 11.4 0.6 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.16 GAX21446.1 - 2.7e-26 92.3 42.8 6.2e-20 71.4 20.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX21446.1 - 6.7e-08 31.8 6.3 6.7e-08 31.8 6.3 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 GAX21446.1 - 0.00041 18.7 1.4 0.00041 18.7 1.4 1.7 2 0 0 2 2 2 1 BT1 family OATP PF03137.20 GAX21446.1 - 0.0081 14.5 5.1 0.024 12.9 0.8 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Ldr_toxin PF13940.6 GAX21446.1 - 0.075 13.1 0.2 6.7 6.9 0.1 2.7 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system YL1 PF05764.13 GAX21447.1 - 0.00017 21.8 24.2 0.00017 21.8 24.2 7.6 3 2 2 5 5 5 1 YL1 nuclear protein Hexapep PF00132.24 GAX21448.1 - 2.4e-14 52.4 8.5 3.5e-05 23.4 0.0 4.3 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAX21448.1 - 2e-05 24.2 7.7 0.00098 18.8 0.1 3.9 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase DUF4988 PF16378.5 GAX21449.1 - 0.082 12.6 1.7 0.31 10.7 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function MatE PF01554.18 GAX21450.1 - 5.4e-23 81.4 30.8 1.1e-20 74.0 8.5 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAX21450.1 - 5.8e-06 26.4 7.8 5.8e-06 26.4 7.8 3.2 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DUF3341 PF11821.8 GAX21450.1 - 2.2 7.9 5.8 1.1 8.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) Ribosomal_L3 PF00297.22 GAX21451.1 - 2.5e-169 563.1 10.4 2.9e-169 562.9 10.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NCBP3 PF10309.9 GAX21452.1 - 1.3e-12 47.4 0.0 2.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 GAX21452.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain Methyltransf_FA PF12248.8 GAX21452.1 - 0.088 13.1 0.0 2.5 8.5 0.0 2.8 3 0 0 3 3 3 0 Farnesoic acid 0-methyl transferase HHV-5_US34A PF17087.5 GAX21452.1 - 0.096 12.8 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus US34A protein family Ank_2 PF12796.7 GAX21453.1 - 1e-08 35.6 0.0 5.1e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX21453.1 - 5.2e-07 30.1 0.0 3.3e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21453.1 - 4.3e-06 26.6 0.0 0.00026 21.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX21453.1 - 0.00058 20.2 0.0 0.002 18.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 GAX21453.1 - 0.018 15.4 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 GAX21453.1 - 0.04 14.8 0.0 0.13 13.2 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily HhH-GPD PF00730.25 GAX21454.1 - 2.7e-05 24.6 0.0 5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein zf-MYND PF01753.18 GAX21455.1 - 7.3e-08 32.4 17.6 1.6e-07 31.3 17.6 1.6 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 GAX21456.1 - 7.4e-08 32.9 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX21456.1 - 2.3e-06 28.0 0.0 0.0021 18.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21456.1 - 2.7e-05 24.2 0.1 0.00026 21.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX21456.1 - 0.0015 18.9 0.0 0.0066 16.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GAX21456.1 - 0.028 14.7 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 GAX21456.1 - 0.041 14.8 0.0 0.086 13.7 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 GAX21457.1 - 7.5e-07 29.7 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX21457.1 - 2e-05 24.6 0.0 0.0052 17.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 GAX21457.1 - 0.011 16.3 0.0 0.1 13.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 GAX21457.1 - 0.095 13.2 0.0 0.69 10.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 GAX21457.1 - 0.1 13.5 0.0 0.19 12.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 GAX21458.1 - 7.6e-11 42.5 1.2 8.7e-09 35.9 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX21458.1 - 1e-09 38.7 0.5 3e-07 30.8 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21458.1 - 8.9e-09 34.9 0.9 9.1e-06 25.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 GAX21458.1 - 2.2e-07 31.0 1.3 0.00013 22.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAX21458.1 - 3.6e-05 24.0 0.2 0.00021 21.5 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 GAX21458.1 - 0.057 14.3 0.0 0.16 12.9 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF155 PF02582.14 GAX21459.1 - 7.5e-23 81.5 0.1 1e-22 81.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2773 PF10971.8 GAX21460.1 - 0.037 14.2 0.8 0.069 13.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) SAM_LFY PF01698.16 GAX21460.1 - 0.13 12.2 0.4 0.28 11.1 0.4 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein SAM domain SNARE PF05739.19 GAX21461.1 - 1.5e-15 56.9 0.1 4.2e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GAX21461.1 - 2.1e-05 24.3 8.8 0.0004 20.1 0.2 2.5 3 0 0 3 3 3 2 Syntaxin Syntaxin_2 PF14523.6 GAX21461.1 - 0.016 15.5 3.4 0.044 14.1 0.4 2.3 2 1 0 2 2 2 0 Syntaxin-like protein DLP_helical PF18709.1 GAX21461.1 - 0.021 14.0 3.1 0.021 14.1 1.2 1.8 1 1 0 1 1 1 0 Dynamin-like helical domain Mit_KHE1 PF10173.9 GAX21461.1 - 0.1 12.6 1.2 0.78 9.8 1.2 2.3 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related APP_E2 PF12925.7 GAX21461.1 - 0.13 11.9 1.8 0.14 11.9 0.3 1.8 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein AdoHcyase PF05221.17 GAX21461.1 - 0.15 11.2 0.7 0.27 10.4 0.2 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase zf-C4H2 PF10146.9 GAX21461.1 - 0.22 11.8 2.3 0.37 11.1 0.1 1.9 1 1 0 2 2 2 0 Zinc finger-containing protein DUF1043 PF06295.12 GAX21461.1 - 0.54 10.3 4.5 1 9.4 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Synaptobrevin PF00957.21 GAX21461.1 - 1.4 8.8 5.6 0.74 9.6 0.7 2.4 2 0 0 2 2 2 0 Synaptobrevin DUF16 PF01519.16 GAX21461.1 - 1.8 9.1 5.9 1.5 9.4 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Semialdhyde_dh PF01118.24 GAX21462.1 - 1.1e-08 35.5 0.2 5.1e-08 33.4 0.1 2.2 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain UCR_hinge PF02320.16 GAX21463.1 - 0.033 14.4 0.2 0.078 13.2 0.2 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein SDP_N PF12278.8 GAX21463.1 - 0.25 11.5 3.5 0.45 10.7 3.5 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal Hydrolase_like PF13242.6 GAX21464.1 - 1.2e-16 60.5 0.0 1.4e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 GAX21464.1 - 1.4e-14 54.0 0.0 5.5e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX21464.1 - 2.8e-12 47.4 0.1 4.3e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX21464.1 - 1.8e-09 37.9 0.0 1.8e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase STI1 PF17830.1 GAX21465.1 - 0.0043 16.9 5.4 0.76 9.8 0.1 3.4 3 0 0 3 3 3 2 STI1 domain Epimerase PF01370.21 GAX21466.1 - 7.6e-18 64.9 0.0 6.8e-17 61.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX21466.1 - 2e-10 40.6 0.0 0.00014 21.4 0.0 2.7 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAX21466.1 - 2.8e-10 40.4 0.0 7.7e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX21466.1 - 0.022 14.3 0.0 0.083 12.4 0.0 1.8 1 1 0 1 1 1 0 NmrA-like family Cupin_4 PF08007.12 GAX21467.1 - 2.4e-17 63.4 0.0 4.6e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 GAX21467.1 - 0.00071 19.4 0.0 0.0051 16.6 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Tudor_3 PF18115.1 GAX21467.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Pkinase PF00069.25 GAX21468.1 - 7.1e-59 199.3 0.9 4.4e-57 193.5 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21468.1 - 1.7e-26 93.0 0.1 1.7e-25 89.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 GAX21468.1 - 2.5e-24 83.0 11.4 1.7e-07 30.3 0.4 4.8 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAX21468.1 - 3.9e-22 77.8 11.3 2.9e-10 39.8 0.7 4.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 GAX21468.1 - 6.4e-22 77.8 10.9 6.4e-10 39.3 3.0 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAX21468.1 - 6.4e-19 66.2 10.1 1.3e-06 27.9 0.3 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAX21468.1 - 5.7e-13 47.7 11.1 0.00019 20.8 0.4 4.5 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 GAX21468.1 - 3.2e-08 33.9 0.9 0.0046 17.3 0.1 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAX21468.1 - 2.4e-06 27.4 1.5 0.037 14.0 0.1 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 GAX21468.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX21468.1 - 8.4e-05 21.5 0.2 0.00015 20.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 GAX21468.1 - 0.00058 19.6 0.7 1 9.0 0.1 3.1 3 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GAX21468.1 - 0.001 18.7 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family EF-hand_11 PF08976.11 GAX21468.1 - 0.0016 19.3 1.8 0.23 12.4 0.1 2.7 2 1 1 3 3 2 1 EF-hand domain APH PF01636.23 GAX21468.1 - 0.0087 16.0 0.0 0.19 11.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX21468.1 - 0.0094 15.3 0.1 0.097 12.0 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAX21468.1 - 0.016 14.1 0.2 0.036 13.0 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain DUF3037 PF11236.8 GAX21468.1 - 0.036 14.5 0.1 2.7 8.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Caleosin PF05042.13 GAX21468.1 - 0.073 13.0 1.4 0.68 9.8 0.2 2.6 1 1 2 3 3 3 0 Caleosin related protein DUF2666 PF10869.8 GAX21468.1 - 0.075 13.2 0.1 0.53 10.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Nod1 PF17114.5 GAX21468.1 - 0.15 12.2 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 HP0268 PF18618.1 GAX21468.1 - 0.17 12.3 1.3 2.2 8.7 0.1 3.0 3 0 0 3 3 3 0 HP0268 Pkinase PF00069.25 GAX21469.1 - 2.6e-58 197.4 3.9 2.7e-58 197.4 1.3 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21469.1 - 2.8e-34 118.6 0.3 5.1e-34 117.7 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX21469.1 - 1.3e-14 54.4 4.2 3.7e-06 27.3 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX21469.1 - 1.1e-12 46.7 3.1 0.00015 21.5 0.2 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 GAX21469.1 - 2.4e-11 42.3 1.6 0.017 14.6 0.0 4.5 4 0 0 4 4 4 3 EF hand Pkinase_fungal PF17667.1 GAX21469.1 - 1.8e-07 30.3 0.0 2.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_8 PF13833.6 GAX21469.1 - 3.6e-07 29.9 2.6 0.17 11.8 0.0 4.7 2 1 2 4 4 4 3 EF-hand domain pair Kdo PF06293.14 GAX21469.1 - 0.00023 20.6 0.1 0.00047 19.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HrpB1_HrpK PF09613.10 GAX21469.1 - 0.0028 17.3 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) YrbL-PhoP_reg PF10707.9 GAX21469.1 - 0.057 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 GAX21469.1 - 0.076 12.6 0.4 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2420 PF10336.9 GAX21469.1 - 0.1 12.6 2.0 0.31 11.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2420) His_Phos_2 PF00328.22 GAX21470.1 - 1.6e-71 241.7 0.0 2.9e-71 240.9 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 GAX21470.1 - 2.1e-38 130.3 0.1 4.7e-38 129.2 0.1 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GAX21470.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF2254 PF10011.9 GAX21471.1 - 1.7e-64 218.0 0.7 2.2e-64 217.6 0.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) DUF4239 PF14023.6 GAX21471.1 - 0.062 13.0 3.2 0.068 12.9 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) CobN-Mg_chel PF02514.16 GAX21472.1 - 0 1120.2 0.0 0 1119.9 0.0 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 GAX21472.1 - 1.2e-52 178.3 1.3 3.2e-52 176.9 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) DUF3958 PF13125.6 GAX21473.1 - 0.38 11.0 2.9 0.87 9.8 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) HA PF03457.14 GAX21474.1 - 7.4e-86 282.5 27.9 5e-18 65.2 0.3 5.4 5 0 0 5 5 5 5 Helicase associated domain DUF4936 PF16290.5 GAX21474.1 - 0.19 12.4 2.2 30 5.4 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4936) zf-MYND PF01753.18 GAX21476.1 - 2.5e-08 33.9 14.2 4.7e-08 33.0 14.2 1.5 1 0 0 1 1 1 1 MYND finger ASTN_2_hairpin PF18577.1 GAX21476.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Astrotactin-2 C-terminal beta-hairpin domain zf-MYND PF01753.18 GAX21477.1 - 4.9e-08 32.9 13.3 1e-07 31.9 13.3 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 GAX21479.1 - 2.7e-08 33.8 13.8 8e-08 32.3 13.8 1.8 1 0 0 1 1 1 1 MYND finger HycA_repressor PF11046.8 GAX21479.1 - 0.1 12.8 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional repressor of hyc and hyp operons zf-HIT PF04438.16 GAX21479.1 - 1.4 8.8 8.9 0.25 11.2 4.1 2.3 2 0 0 2 2 2 0 HIT zinc finger zf-Mss51 PF13824.6 GAX21479.1 - 2.2 8.4 9.5 0.13 12.4 3.8 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_1 PF00515.28 GAX21480.1 - 2.1e-09 36.8 0.3 0.21 11.5 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21480.1 - 8.2e-09 34.9 1.1 0.73 10.1 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21480.1 - 7.3e-07 29.4 3.1 0.022 15.0 0.8 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX21480.1 - 7.4e-07 28.9 0.4 8.4 6.9 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX21480.1 - 1e-05 25.9 4.8 1 9.9 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX21480.1 - 3.2e-05 24.5 2.9 0.29 11.8 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX21480.1 - 0.0002 21.5 2.5 5.6 7.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX21480.1 - 0.00095 19.0 0.6 1.4 9.1 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX21480.1 - 0.004 17.7 5.6 2.5 8.9 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX21480.1 - 0.032 15.0 5.9 4.9 8.2 0.0 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX21480.1 - 0.034 14.0 2.5 12 5.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX21480.1 - 0.047 13.4 0.1 10 5.9 0.0 2.9 2 1 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 GAX21480.1 - 0.089 13.0 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DnaJ PF00226.31 GAX21481.1 - 5.7e-23 80.8 0.9 5.7e-23 80.8 0.9 1.6 2 0 0 2 2 2 1 DnaJ domain NYN_YacP PF05991.11 GAX21482.1 - 0.00081 19.4 0.1 0.0015 18.5 0.1 1.4 1 1 0 1 1 1 1 YacP-like NYN domain DUF3626 PF12294.8 GAX21482.1 - 0.16 11.0 0.0 0.19 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) DUF1349 PF07081.11 GAX21483.1 - 3e-38 131.3 0.1 5.6e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) RmlD_sub_bind PF04321.17 GAX21483.1 - 3.9e-26 91.8 0.2 3.3e-25 88.8 0.2 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAX21483.1 - 2.1e-21 76.5 0.0 2.8e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX21483.1 - 4.3e-15 55.9 0.0 6.2e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX21483.1 - 2e-08 33.7 0.0 1.8e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAX21483.1 - 2.2e-05 23.8 0.0 0.041 13.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GH43_C2 PF17851.1 GAX21483.1 - 0.005 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain 3Beta_HSD PF01073.19 GAX21483.1 - 0.0063 15.6 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 GAX21483.1 - 0.034 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain ANAPC4_WD40 PF12894.7 GAX21484.1 - 0.0034 17.6 0.2 24 5.3 0.0 5.4 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AA_kinase PF00696.28 GAX21485.1 - 3.3e-36 125.1 0.0 6.8e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 GAX21485.1 - 1.3e-10 40.4 1.7 3.2e-09 35.8 1.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family WD40 PF00400.32 GAX21486.1 - 1.3e-08 35.3 4.6 0.028 15.3 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 GAX21486.1 - 2.5e-07 30.2 7.9 2.5e-07 30.2 7.9 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 GAX21486.1 - 0.08 13.2 7.8 0.18 12.0 7.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family QVR PF17064.5 GAX21486.1 - 0.22 11.8 4.3 0.52 10.6 4.3 1.6 1 0 0 1 1 1 0 Sleepless protein DZR PF12773.7 GAX21486.1 - 6.7 6.8 11.0 78 3.4 11.0 2.6 1 1 0 1 1 1 0 Double zinc ribbon SBF PF01758.16 GAX21487.1 - 5e-29 101.4 14.3 8.9e-29 100.5 14.3 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 GAX21487.1 - 2.5e-13 50.0 19.8 3e-13 49.8 19.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SRP54 PF00448.22 GAX21488.1 - 4.6e-76 254.8 0.6 7.4e-76 254.2 0.0 1.7 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAX21488.1 - 2.8e-26 92.0 0.8 2.8e-26 92.0 0.8 3.6 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 GAX21488.1 - 4.6e-14 52.4 2.9 1.3e-13 51.0 2.9 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 GAX21488.1 - 2.1e-07 30.5 0.7 9.2e-07 28.3 0.0 2.2 2 1 1 3 3 3 1 Zeta toxin AAA_16 PF13191.6 GAX21488.1 - 9.7e-07 29.3 0.0 4.1e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 GAX21488.1 - 1.9e-06 27.6 0.4 0.00012 21.7 0.3 3.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAX21488.1 - 1.6e-05 24.7 0.1 7.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX21488.1 - 5.1e-05 23.5 0.1 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Med8 PF10232.9 GAX21488.1 - 0.00059 19.5 0.0 0.27 10.8 0.0 2.6 2 1 1 3 3 3 1 Mediator of RNA polymerase II transcription complex subunit 8 CbiA PF01656.23 GAX21488.1 - 0.00097 19.2 0.0 0.0038 17.3 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Arf PF00025.21 GAX21488.1 - 0.007 15.8 0.2 0.075 12.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family APS_kinase PF01583.20 GAX21488.1 - 0.0073 16.2 0.6 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_22 PF13401.6 GAX21488.1 - 0.0074 16.6 0.4 0.057 13.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAX21488.1 - 0.0083 16.5 0.0 0.027 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 GAX21488.1 - 0.011 14.7 0.0 0.011 14.7 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 GAX21488.1 - 0.014 15.7 0.1 0.038 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 GAX21488.1 - 0.015 15.3 0.6 0.14 12.1 0.4 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 GAX21488.1 - 0.017 15.2 0.9 0.075 13.1 0.1 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 GAX21488.1 - 0.017 15.5 0.1 0.18 12.2 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 GAX21488.1 - 0.028 13.3 0.8 4.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 GAX21488.1 - 0.034 14.0 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 GAX21488.1 - 0.054 13.3 0.8 6.5 6.5 0.0 2.6 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cys_Met_Meta_PP PF01053.20 GAX21488.1 - 0.056 12.0 0.0 0.089 11.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Thymidylate_kin PF02223.17 GAX21488.1 - 0.082 12.6 0.1 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase ATPase PF06745.13 GAX21488.1 - 0.085 12.2 1.1 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 GAX21488.1 - 0.092 12.5 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain RasGAP_C PF03836.15 GAX21488.1 - 0.2 11.8 2.6 0.55 10.4 0.3 2.3 2 0 0 2 2 2 0 RasGAP C-terminus GTP_EFTU PF00009.27 GAX21488.1 - 0.28 10.7 5.1 0.098 12.2 0.2 2.6 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.6 GAX21488.1 - 7.8 6.9 8.1 0.49 10.8 0.1 3.1 3 2 0 3 3 2 0 AAA domain Cwf_Cwc_15 PF04889.12 GAX21489.1 - 3.1e-58 197.4 17.5 3.5e-58 197.2 17.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 GAX21489.1 - 0.022 14.6 24.7 0.02 14.8 23.5 1.5 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing YL1 PF05764.13 GAX21489.1 - 1.3 9.0 29.8 0.27 11.3 26.2 1.6 1 1 1 2 2 2 0 YL1 nuclear protein DNA_pol_phi PF04931.13 GAX21489.1 - 3.2 5.7 24.6 3.2 5.7 24.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GAX21489.1 - 6.7 4.9 15.2 7.4 4.7 15.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GAX21489.1 - 9.6 4.9 12.6 12 4.5 12.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nas2_N PF18265.1 GAX21490.1 - 2.7e-20 72.1 0.1 6.1e-20 70.9 0.1 1.6 1 1 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 GAX21490.1 - 3.9e-06 26.6 0.2 1.8e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX21490.1 - 0.00012 22.3 0.0 0.00029 21.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 GAX21490.1 - 0.00064 20.0 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 GAX21490.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 PDZ domain TLE_N PF03920.15 GAX21490.1 - 0.12 12.5 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain FAM131 PF15010.6 GAX21490.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative cell signalling OB_NTP_bind PF07717.16 GAX21491.1 - 0.094 13.1 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAX21492.1 - 4.8e-20 71.8 0.0 4.8e-20 71.8 0.0 4.1 5 1 0 5 5 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX21492.1 - 7.6e-14 51.8 0.0 2.8e-13 50.0 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX21492.1 - 3.6e-13 49.8 0.0 8.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX21492.1 - 1.7e-06 28.0 0.0 4.8e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX21492.1 - 0.0005 20.3 0.1 0.0024 18.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX21492.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAX21492.1 - 0.021 13.9 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 GAX21492.1 - 0.04 14.4 0.1 0.17 12.4 0.0 2.1 2 0 0 2 2 1 0 ABC transporter CPP1-like PF11833.8 GAX21492.1 - 0.052 13.2 3.0 0.21 11.2 3.0 2.0 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AAA_23 PF13476.6 GAX21492.1 - 0.059 13.9 0.1 0.059 13.9 0.1 3.9 3 2 1 4 4 4 0 AAA domain SRP54 PF00448.22 GAX21492.1 - 0.092 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 GAX21492.1 - 0.092 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 GAX21492.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 GAX21492.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAX21492.1 - 0.38 10.7 1.8 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 GAX21492.1 - 1.3 8.5 3.6 0.31 10.5 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region ABC1 PF03109.16 GAX21494.1 - 2.4e-32 111.6 0.0 7e-32 110.1 0.0 1.9 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX21494.1 - 0.0083 16.1 0.1 0.048 13.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX21494.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Phytochelatin PF05023.14 GAX21495.1 - 4.4e-83 277.7 0.0 5.8e-83 277.3 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase NAD_binding_10 PF13460.6 GAX21496.1 - 5.4e-26 91.6 0.1 2.5e-25 89.5 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX21496.1 - 6.4e-07 29.2 0.0 1.6e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family DapB_N PF01113.20 GAX21496.1 - 1.8e-05 24.8 0.6 9.8e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAX21496.1 - 0.00058 20.3 0.5 0.0023 18.3 0.1 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GAX21496.1 - 0.00058 19.1 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Shikimate_DH PF01488.20 GAX21496.1 - 0.0029 17.7 0.1 0.0073 16.4 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 GAX21496.1 - 0.0044 16.5 0.1 0.035 13.6 0.1 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAX21496.1 - 0.01 16.1 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 GAX21496.1 - 0.027 14.4 0.0 0.2 11.6 0.1 2.2 2 1 1 3 3 3 0 KR domain Polysacc_synt_2 PF02719.15 GAX21496.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABC_tran PF00005.27 GAX21497.1 - 6.2e-47 159.6 0.0 1e-23 84.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAX21497.1 - 1.8e-19 70.7 6.7 8.8e-09 35.6 0.0 4.7 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX21497.1 - 4.8e-06 26.2 0.0 0.57 9.6 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX21497.1 - 0.00032 20.5 0.0 3.2 7.3 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAX21497.1 - 0.00037 20.2 2.2 0.072 12.8 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX21497.1 - 0.0049 17.4 2.8 0.62 10.5 0.5 2.2 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 GAX21497.1 - 0.012 16.3 1.1 0.25 12.1 0.0 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF4162) AAA_33 PF13671.6 GAX21497.1 - 0.075 13.2 0.2 19 5.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAX21497.1 - 0.11 12.5 0.5 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 GAX21497.1 - 0.16 11.2 0.1 29 3.9 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 GAX21497.1 - 0.18 11.3 1.5 15 5.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAX21497.1 - 0.2 11.6 2.5 7.5 6.6 0.4 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 GAX21497.1 - 0.7 8.5 5.6 0.17 10.5 0.1 2.3 3 0 0 3 3 3 0 AAA domain PHD PF00628.29 GAX21498.1 - 3.4e-11 42.8 8.7 6.6e-11 41.9 8.7 1.5 1 0 0 1 1 1 1 PHD-finger PWWP PF00855.17 GAX21498.1 - 1.6e-09 38.0 0.1 4.2e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 GAX21498.1 - 0.062 12.9 2.8 0.12 11.9 2.8 1.5 1 0 0 1 1 1 0 PHD-finger ADK_lid PF05191.14 GAX21498.1 - 0.46 10.5 2.5 1.1 9.3 2.5 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 GAX21498.1 - 0.76 9.7 7.8 0.089 12.7 3.3 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Mito_carr PF00153.27 GAX21499.1 - 1.9e-44 149.5 7.0 6.5e-20 70.9 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DIRP PF06584.13 GAX21500.1 - 3.1e-10 40.2 0.2 2.2e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 DIRP OGG_N PF07934.12 GAX21501.1 - 1.9e-19 70.0 0.0 3.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 GAX21501.1 - 1e-12 48.5 0.0 1.8e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAX21501.1 - 0.0045 16.8 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_23 PF13476.6 GAX21502.1 - 1.3e-10 42.2 0.1 1.3e-10 42.2 0.1 3.1 3 1 0 3 3 3 1 AAA domain Metallophos PF00149.28 GAX21502.1 - 1.5e-08 35.4 0.1 2.8e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX21502.1 - 1.1e-05 25.8 0.4 0.00033 20.9 0.0 2.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain eIF-1a PF01176.19 GAX21502.1 - 0.011 15.5 0.0 0.064 13.1 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 SMC_N PF02463.19 GAX21502.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF3656 PF12392.8 GAX21502.1 - 0.75 10.5 5.7 0.29 11.8 0.7 2.9 3 0 0 3 3 3 0 Collagenase Exonuc_VII_L PF02601.15 GAX21502.1 - 2.5 7.6 20.2 0.94 9.0 9.2 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit zf-RING_11 PF17123.5 GAX21504.1 - 1.8e-07 30.8 1.2 6.1e-07 29.1 1.2 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAX21504.1 - 2.8e-07 30.8 6.9 6.5e-07 29.6 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX21504.1 - 0.00015 21.5 4.8 0.0011 18.8 5.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX21504.1 - 0.00076 19.3 4.5 0.00076 19.3 4.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX21504.1 - 0.0011 19.0 6.0 0.0027 17.7 6.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX21504.1 - 0.0027 17.5 6.9 0.0063 16.4 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sec2p PF06428.11 GAX21504.1 - 0.0061 16.5 0.9 0.0061 16.5 0.9 3.6 4 1 0 4 4 4 1 GDP/GTP exchange factor Sec2p TPR_MLP1_2 PF07926.12 GAX21504.1 - 0.014 15.5 21.8 0.014 15.5 21.8 3.2 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein zf-ANAPC11 PF12861.7 GAX21504.1 - 0.13 12.3 5.6 0.28 11.3 5.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAX21504.1 - 0.23 11.3 9.9 0.28 11.1 8.1 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAX21504.1 - 1 9.7 16.8 0.22 11.8 11.8 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX21504.1 - 1.2 9.2 8.5 3.6 7.6 8.5 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Csm1_N PF18504.1 GAX21504.1 - 1.8 8.9 21.4 0.13 12.7 4.1 4.2 4 0 0 4 4 4 0 Csm1 N-terminal domain zf-C3HC4_4 PF15227.6 GAX21504.1 - 1.9 8.7 9.3 5.6 7.2 8.0 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prefoldin PF02996.17 GAX21504.1 - 2.9 7.8 15.5 1.9 8.4 2.4 3.4 2 2 1 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 GAX21504.1 - 3.3 7.9 16.1 6.9 6.8 3.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Zn_ribbon_17 PF17120.5 GAX21504.1 - 9.2 6.0 15.9 0.45 10.2 9.9 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Spermine_synth PF01564.17 GAX21505.1 - 2.1e-26 92.5 0.0 4e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 GAX21505.1 - 1.3e-22 80.1 0.0 2.7e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase SET PF00856.28 GAX21505.1 - 0.087 13.2 0.0 5.2 7.4 0.0 2.6 1 1 0 1 1 1 0 SET domain FAT PF02259.23 GAX21506.1 - 3e-31 108.9 7.2 6.3e-31 107.9 7.2 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 GAX21506.1 - 2e-18 67.1 0.0 4.8e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GAX21506.1 - 0.015 15.1 0.0 0.051 13.4 0.0 1.9 1 0 0 1 1 1 0 FATC domain Cse1 PF08506.10 GAX21506.1 - 0.13 11.0 0.1 5.9 5.6 0.0 2.9 3 0 0 3 3 3 0 Cse1 DEAD PF00270.29 GAX21507.1 - 1.7e-39 135.4 0.0 3.9e-38 131.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX21507.1 - 1.2e-18 67.5 0.0 3.7e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX21507.1 - 7.7e-07 29.3 0.0 4.3e-06 26.8 0.0 2.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX21507.1 - 0.025 13.8 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DNA_pol_E_B PF04042.16 GAX21508.1 - 1.3e-26 93.3 0.0 1.9e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 GAX21508.1 - 3.2e-21 75.8 0.0 2.9e-20 72.7 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Rubredoxin_2 PF18073.1 GAX21509.1 - 0.041 13.6 1.2 0.073 12.8 1.2 1.4 1 0 0 1 1 1 0 Rubredoxin metal binding domain Copine PF07002.16 GAX21510.1 - 1e-47 162.4 0.0 1.5e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX21510.1 - 1e-11 45.0 0.0 7.5e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX21510.1 - 8e-05 22.8 0.0 0.00029 21.0 0.0 1.9 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.28 GAX21510.1 - 0.00095 19.5 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TPR_12 PF13424.6 GAX21511.1 - 7.2e-31 106.3 0.5 2e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX21511.1 - 7.5e-20 69.9 4.4 6.9e-07 28.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX21511.1 - 1.2e-19 69.5 0.3 1.7e-06 27.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21511.1 - 9.4e-17 59.7 5.7 0.00099 19.0 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX21511.1 - 1.2e-11 43.8 0.1 0.00067 19.5 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX21511.1 - 1.4e-11 43.6 3.2 0.0014 18.7 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX21511.1 - 6.1e-05 22.6 4.7 1.2 8.9 0.0 5.0 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 GAX21511.1 - 0.00014 21.9 0.1 0.024 14.8 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX21511.1 - 0.00027 21.5 2.0 10 6.9 0.1 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX21511.1 - 0.0016 17.9 2.3 0.0016 17.9 2.3 1.9 2 0 0 2 2 2 1 MalT-like TPR region PPR PF01535.20 GAX21511.1 - 0.0025 17.9 0.3 3.5 8.1 0.0 3.9 4 1 1 5 5 5 1 PPR repeat TPR_6 PF13174.6 GAX21511.1 - 0.0032 18.0 3.2 0.96 10.2 0.0 4.3 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX21511.1 - 0.0049 17.1 0.3 8.5 7.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF5113 PF17140.4 GAX21511.1 - 0.024 14.5 0.4 0.054 13.3 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5113) TPR_14 PF13428.6 GAX21511.1 - 0.03 15.1 5.8 29 5.9 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat SPO22 PF08631.10 GAX21511.1 - 0.073 12.6 0.1 0.99 8.8 0.0 2.2 2 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like MatE PF01554.18 GAX21513.1 - 5.5e-30 104.1 21.0 3.3e-18 65.8 3.6 3.0 3 0 0 3 3 3 2 MatE VPS13_mid_rpt PF16910.5 GAX21514.1 - 0.0041 16.6 0.5 0.27 10.6 0.1 2.4 2 0 0 2 2 2 2 Repeating coiled region of VPS13 TPR_2 PF07719.17 GAX21515.1 - 0.00046 20.1 0.4 0.22 11.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX21515.1 - 0.0039 16.9 0.4 0.18 11.7 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21515.1 - 0.032 14.5 2.2 2.5 8.4 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 GAX21516.1 - 3.1e-07 30.9 0.0 6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Syntaxin PF00804.25 GAX21517.1 - 5.9e-07 29.4 8.2 0.00029 20.6 1.6 2.3 2 0 0 2 2 2 2 Syntaxin SNARE PF05739.19 GAX21517.1 - 1.5e-05 24.9 9.8 4.5e-05 23.3 2.6 2.4 2 0 0 2 2 2 1 SNARE domain Apolipoprotein PF01442.18 GAX21517.1 - 0.00028 20.8 2.9 0.00028 20.8 2.9 2.4 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain AAA_13 PF13166.6 GAX21517.1 - 0.0057 15.4 7.4 0.019 13.6 1.4 2.0 2 0 0 2 2 2 2 AAA domain Dynamin_M PF01031.20 GAX21517.1 - 0.0058 15.9 0.6 0.0058 15.9 0.6 1.5 2 0 0 2 2 2 1 Dynamin central region Tom5 PF10642.9 GAX21517.1 - 0.0095 15.9 0.0 0.055 13.5 0.0 2.3 2 0 0 2 2 1 1 Mitochondrial import receptor subunit or translocase SF-assemblin PF06705.11 GAX21517.1 - 0.015 14.6 8.1 0.099 12.0 1.1 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin ApoLp-III PF07464.11 GAX21517.1 - 0.02 15.0 8.3 0.23 11.5 2.5 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Filament PF00038.21 GAX21517.1 - 0.037 13.6 10.6 0.53 9.8 1.5 2.2 2 0 0 2 2 2 0 Intermediate filament protein RsbU_N PF08673.10 GAX21517.1 - 0.088 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Syntaxin_2 PF14523.6 GAX21517.1 - 0.095 13.1 8.8 1.1 9.7 2.6 2.8 2 1 1 3 3 3 0 Syntaxin-like protein Borrelia_lipo_1 PF05714.11 GAX21517.1 - 0.2 11.4 3.4 0.15 11.8 0.6 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein YtxH PF12732.7 GAX21517.1 - 0.33 11.5 3.0 0.4 11.3 0.9 2.2 2 0 0 2 2 2 0 YtxH-like protein CSN5_C PF18323.1 GAX21517.1 - 0.41 11.6 4.3 0.28 12.1 1.7 2.0 2 0 0 2 2 1 0 Cop9 signalosome subunit 5 C-terminal domain Latarcin PF10279.9 GAX21517.1 - 0.55 10.7 6.7 1.1 9.8 0.2 2.9 2 1 0 2 2 2 0 Latarcin precursor Allexi_40kDa PF05549.11 GAX21517.1 - 0.93 9.0 6.9 0.69 9.4 0.5 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Nup88 PF10168.9 GAX21517.1 - 1.1 7.0 9.4 0.023 12.5 2.7 1.5 2 0 0 2 2 2 0 Nuclear pore component SKA1 PF07160.12 GAX21517.1 - 1.1 9.0 8.2 2.8 7.7 1.3 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4047 PF13256.6 GAX21517.1 - 1.5 9.1 5.6 0.99 9.6 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF724 PF05266.14 GAX21517.1 - 1.7 8.4 7.7 2.2 8.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF16 PF01519.16 GAX21517.1 - 2 9.0 9.6 1.2 9.6 1.5 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Baculo_p24 PF05073.12 GAX21517.1 - 2.6 7.8 6.7 1.9 8.2 0.9 2.3 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Laminin_II PF06009.12 GAX21517.1 - 3.5 7.6 9.7 3.9 7.5 1.0 3.2 2 1 1 3 3 3 0 Laminin Domain II BST2 PF16716.5 GAX21517.1 - 4.9 7.8 10.2 2.5 8.7 1.2 2.6 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Tup_N PF08581.10 GAX21517.1 - 6.3 7.2 13.1 1.5 9.2 2.2 3.4 2 1 1 3 3 3 0 Tup N-terminal UPF0242 PF06785.11 GAX21517.1 - 7.1 6.7 10.9 9.4 6.3 1.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Utp21 PF04192.12 GAX21518.1 - 1.6e-36 126.0 0.0 2.7e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 GAX21518.1 - 1.1e-15 57.7 8.3 4.1e-05 24.3 0.0 7.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX21518.1 - 1.5e-11 44.4 0.0 3.2e-05 24.1 0.0 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX21518.1 - 0.011 16.2 0.4 5.3 7.7 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain Cytochrom_D1 PF02239.16 GAX21518.1 - 0.019 13.5 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 GAX21518.1 - 0.038 12.9 0.0 0.081 11.9 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Inhibitor_I29 PF08246.12 GAX21519.1 - 8.5e-05 22.9 13.6 0.023 15.1 1.9 3.3 3 0 0 3 3 3 2 Cathepsin propeptide inhibitor domain (I29) Nucleoporin_FG PF13634.6 GAX21519.1 - 0.02 15.7 18.7 0.092 13.6 13.0 3.6 2 2 0 2 2 2 0 Nucleoporin FG repeat region DUF3449 PF11931.8 GAX21520.1 - 2.5e-63 213.2 0.0 4.2e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 GAX21520.1 - 7.6e-20 70.3 3.7 9.1e-20 70.1 2.4 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal SF3A3 PF16837.5 GAX21520.1 - 1.7e-12 47.7 0.3 4.5e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Abhydrolase_1 PF00561.20 GAX21521.1 - 1.4e-18 67.5 0.0 2e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX21521.1 - 8.1e-17 62.6 0.1 1.2e-16 62.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX21521.1 - 8.6e-15 54.6 0.0 5.2e-14 52.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 GAX21521.1 - 5e-08 32.8 0.0 8.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 GAX21521.1 - 1.7e-05 24.6 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 GAX21521.1 - 9.5e-05 22.3 0.0 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.7 GAX21521.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GAX21521.1 - 0.0018 18.5 0.1 0.0044 17.2 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 GAX21521.1 - 0.0025 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 GAX21521.1 - 0.003 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 GAX21521.1 - 0.021 14.2 0.0 0.089 12.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 GAX21521.1 - 0.025 13.3 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF2048 PF09752.9 GAX21521.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 UPF0227 PF05728.12 GAX21521.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) NUMOD1 PF07453.13 GAX21522.1 - 1.7e-06 28.1 0.0 0.00043 20.4 0.0 2.7 2 0 0 2 2 2 2 NUMOD1 domain PDZ PF00595.24 GAX21522.1 - 0.00044 20.6 0.0 0.31 11.4 0.0 3.7 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 GAX21522.1 - 0.0034 17.2 0.2 0.26 11.1 0.0 3.4 3 0 0 3 3 3 1 PDZ domain HTH_28 PF13518.6 GAX21522.1 - 0.24 11.6 1.2 3.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain tRNA_U5-meth_tr PF05958.11 GAX21523.1 - 4.8e-10 39.0 0.0 1.4e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 GAX21523.1 - 2.5e-07 31.3 0.3 9.9e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX21523.1 - 2.6e-07 30.6 0.1 4.9e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX21523.1 - 2.7e-07 30.3 0.2 7.4e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 GAX21523.1 - 6.5e-05 22.5 1.9 7.9e-05 22.2 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 GAX21523.1 - 7.2e-05 23.5 0.1 0.00025 21.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX21523.1 - 0.0008 20.0 0.1 0.0025 18.4 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX21523.1 - 0.0012 18.7 0.3 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX21523.1 - 0.0039 16.6 0.1 0.0067 15.8 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.8 GAX21523.1 - 0.0048 16.4 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_32 PF13679.6 GAX21523.1 - 0.0052 16.8 0.1 0.018 15.1 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX21523.1 - 0.021 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.16 GAX21523.1 - 0.079 12.1 0.7 0.2 10.7 0.0 1.9 3 0 0 3 3 3 0 mRNA capping enzyme Cyclin_N PF00134.23 GAX21525.1 - 3e-15 56.1 0.0 4.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX21525.1 - 9.3e-06 25.7 0.2 1.9e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain PEMT PF04191.13 GAX21526.1 - 0.00065 20.1 1.8 0.00065 20.1 1.8 2.8 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF962 PF06127.11 GAX21526.1 - 6.3 7.0 12.8 1.6 8.8 5.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Cyclin_N PF00134.23 GAX21527.1 - 4.9e-18 65.1 1.1 7e-18 64.6 0.4 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX21527.1 - 0.006 16.7 2.4 0.015 15.4 0.1 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain FliMN_C PF01052.20 GAX21527.1 - 0.079 13.0 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term Exo_endo_phos PF03372.23 GAX21528.1 - 6e-13 48.8 0.0 5.7e-12 45.6 0.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAX21528.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BpuSI_N PF15516.6 GAX21528.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 BpuSI N-terminal domain Metallopep PF12044.8 GAX21529.1 - 0.0031 16.2 0.0 0.0031 16.2 0.0 1.7 2 0 0 2 2 2 1 Putative peptidase family Reprolysin_5 PF13688.6 GAX21529.1 - 0.0075 16.4 0.2 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX21529.1 - 0.012 16.1 0.9 0.038 14.5 0.0 2.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.8 GAX21529.1 - 0.034 13.8 0.5 0.36 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Peptidase_M10 PF00413.24 GAX21529.1 - 0.039 13.8 0.0 0.072 12.9 0.0 1.4 1 1 0 1 1 1 0 Matrixin DUF2207 PF09972.9 GAX21529.1 - 0.064 12.0 0.0 0.064 12.0 0.0 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Reprolysin_4 PF13583.6 GAX21529.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 GAX21529.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A EMP24_GP25L PF01105.24 GAX21529.1 - 3.8 7.4 7.8 2 8.3 0.1 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Metallophos PF00149.28 GAX21530.1 - 2.3e-14 54.4 0.9 1.7e-13 51.6 0.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4329 PF14220.6 GAX21530.1 - 0.021 14.8 0.2 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) CN_hydrolase PF00795.22 GAX21531.1 - 6.4e-46 156.8 0.0 8.4e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MOZ_SAS PF01853.18 GAX21532.1 - 1.1e-79 266.2 0.9 1.6e-79 265.7 0.9 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAX21532.1 - 5.4e-21 73.9 5.1 5.4e-21 73.9 5.1 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 GAX21532.1 - 4.5e-12 45.7 2.1 9.9e-12 44.6 2.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pkinase PF00069.25 GAX21533.1 - 0.00021 20.8 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPT PF03151.16 GAX21534.1 - 5e-13 49.0 11.7 7.2e-13 48.5 11.7 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAX21534.1 - 0.0034 16.6 4.2 0.0034 16.6 4.2 2.7 3 1 0 3 3 3 1 UAA transporter family EamA PF00892.20 GAX21534.1 - 0.0035 17.5 23.5 0.015 15.5 7.2 3.1 2 2 0 2 2 2 2 EamA-like transporter family DUF707 PF05212.12 GAX21534.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF707) Lipase_GDSL_2 PF13472.6 GAX21535.1 - 9.7e-09 35.9 0.1 1.3e-08 35.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX21535.1 - 0.00046 20.2 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAX21536.1 - 4.5e-09 37.0 0.2 5.8e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX21536.1 - 0.00046 20.2 0.0 0.00078 19.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CENP-I PF07778.11 GAX21537.1 - 0.5 9.0 2.2 3.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Mis6 EndoU_bacteria PF14436.6 GAX21537.1 - 2.1 8.7 6.0 3.4 8.0 0.2 2.5 2 0 0 2 2 2 0 Bacterial EndoU nuclease Lactamase_B_6 PF16661.5 GAX21538.1 - 1.2e-25 90.1 0.0 2.5e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 GAX21538.1 - 1.7e-13 50.8 0.0 4.2e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain CPSF100_C PF13299.6 GAX21538.1 - 1e-10 42.1 0.6 3.9e-10 40.2 0.0 2.3 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta_lactamase3 PF17030.5 GAX21538.1 - 0.049 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family RabGAP-TBC PF00566.18 GAX21539.1 - 0.0012 18.6 0.4 0.0047 16.6 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Galactosyl_T PF01762.21 GAX21540.1 - 4.9e-08 33.0 0.2 7.3e-08 32.5 0.2 1.3 1 0 0 1 1 1 1 Galactosyltransferase PS_pyruv_trans PF04230.13 GAX21541.1 - 7.8e-16 58.8 0.2 3.2e-15 56.8 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase Galactosyl_T PF01762.21 GAX21542.1 - 2.4e-07 30.8 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Aa_trans PF01490.18 GAX21543.1 - 1.2e-39 136.2 29.0 4e-39 134.5 29.0 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PhoR PF11808.8 GAX21543.1 - 0.19 12.1 0.0 0.19 12.1 0.0 3.8 4 0 0 4 4 4 0 Phosphate regulon sensor protein PhoR zf-RING_2 PF13639.6 GAX21545.1 - 2.9e-11 43.5 13.1 6.6e-11 42.4 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX21545.1 - 2.5e-07 30.4 11.4 6.6e-07 29.1 11.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX21545.1 - 2e-06 27.4 7.3 5.9e-06 25.9 7.3 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAX21545.1 - 4.1e-06 27.0 14.9 4.1e-06 27.0 14.9 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAX21545.1 - 8.1e-05 22.4 6.8 0.00019 21.2 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX21545.1 - 0.00046 20.0 11.7 0.00046 20.0 11.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX21545.1 - 0.00095 19.1 5.3 0.00095 19.1 5.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAX21545.1 - 0.0025 17.8 9.2 0.0063 16.5 8.5 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAX21545.1 - 0.0079 16.1 10.1 0.0079 16.1 10.1 2.2 2 1 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.8 GAX21545.1 - 0.12 12.6 13.3 1.1 9.5 11.9 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX21545.1 - 1.5 8.5 13.0 0.39 10.4 9.3 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 GAX21545.1 - 2.8 7.8 7.9 17 5.3 7.9 2.1 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Draxin PF15550.6 GAX21546.1 - 0.08 12.8 1.2 0.11 12.4 1.2 1.4 1 0 0 1 1 1 0 Draxin DUF4647 PF15504.6 GAX21546.1 - 0.63 9.1 8.1 1 8.4 7.6 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4647) DUF5305 PF17231.2 GAX21548.1 - 0.05 13.0 0.1 0.083 12.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4856 PF16148.5 GAX21548.1 - 0.051 12.6 0.3 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4856) Globin PF00042.22 GAX21550.1 - 7.1e-11 42.6 0.0 1.2e-10 41.9 0.0 1.3 2 0 0 2 2 2 1 Globin Lactamase_B PF00753.27 GAX21553.1 - 8.7e-07 29.1 0.8 8.9e-06 25.8 0.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAX21553.1 - 0.03 13.8 0.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase superfamily domain CBM_6 PF03422.15 GAX21554.1 - 2.9e-40 137.4 8.4 6.6e-24 84.6 0.5 3.3 3 0 0 3 3 3 2 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX21554.1 - 9.1e-29 100.8 12.0 1.5e-28 100.1 12.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX21554.1 - 3.9e-12 46.3 5.7 1.6e-05 25.0 0.1 3.7 4 0 0 4 4 4 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX21554.1 - 2.3e-05 24.6 3.4 0.11 12.8 0.2 2.5 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) CopC PF04234.12 GAX21554.1 - 0.0099 16.9 0.1 10 7.2 0.0 2.8 3 0 0 3 3 3 2 CopC domain DUF5011 PF16403.5 GAX21554.1 - 0.048 13.8 0.5 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) DEC-1_N PF04625.13 GAX21554.1 - 0.12 11.3 1.4 0.19 10.7 1.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SOBP PF15279.6 GAX21554.1 - 9.6 6.7 9.5 15 6.0 9.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PXA PF02194.15 GAX21558.1 - 0.086 12.8 0.6 0.17 11.9 0.6 1.4 1 0 0 1 1 1 0 PXA domain C2 PF00168.30 GAX21560.1 - 1.3e-07 31.8 0.0 9.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 C2 domain TerD PF02342.18 GAX21560.1 - 3.4e-06 26.7 0.0 0.0086 15.6 0.0 2.8 2 1 0 2 2 2 2 TerD domain LAP1C PF05609.12 GAX21561.1 - 0.87 8.6 6.6 0.52 9.3 5.4 1.3 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TerD PF02342.18 GAX21562.1 - 0.23 10.9 0.0 3.1 7.2 0.0 2.6 2 1 0 2 2 2 0 TerD domain TerD PF02342.18 GAX21563.1 - 1.1e-15 57.7 0.0 2.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 TerD domain C2 PF00168.30 GAX21563.1 - 2.9e-10 40.3 0.0 5.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain TerD PF02342.18 GAX21564.1 - 1.4e-13 50.8 0.0 9.2e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 TerD domain C2 PF00168.30 GAX21564.1 - 8.2e-07 29.3 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Glyco_transf_8 PF01501.20 GAX21565.1 - 3.4e-07 30.1 0.3 0.00026 20.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAX21565.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative S10_plectin PF03501.15 GAX21567.1 - 1.5e-37 127.5 0.1 1.7e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF4687 PF15747.5 GAX21567.1 - 0.082 13.4 0.3 0.12 12.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) Glyco_transf_8 PF01501.20 GAX21568.1 - 0.00034 20.3 0.7 1.1 8.8 0.1 2.9 2 1 1 3 3 3 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAX21568.1 - 0.00071 19.0 0.1 0.0023 17.3 0.1 1.7 2 0 0 2 2 2 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 GAX21569.1 - 5.2e-06 26.2 0.1 0.011 15.4 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAX21569.1 - 0.0033 16.8 0.1 0.006 16.0 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative ThiF PF00899.21 GAX21570.1 - 1.8e-88 296.0 0.0 1.6e-67 227.4 0.0 2.5 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAX21570.1 - 9.9e-78 261.5 0.5 2.2e-77 260.4 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GAX21570.1 - 3e-28 98.4 0.2 7.2e-28 97.1 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GAX21570.1 - 9.6e-20 70.6 0.8 2.5e-19 69.2 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 GAX21570.1 - 1.4e-17 63.6 0.4 2.8e-17 62.7 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain Zip PF02535.22 GAX21574.1 - 0.42 9.8 2.6 0.46 9.6 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 GAX21574.1 - 0.58 9.5 11.4 0.66 9.3 11.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PBP1_TM PF14812.6 GAX21574.1 - 3.5 8.0 11.2 4.4 7.8 11.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PBP1_TM PF14812.6 GAX21575.1 - 0.0083 16.5 5.3 0.0083 16.5 5.3 2.4 2 1 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 GAX21575.1 - 0.02 14.9 0.8 0.033 14.2 0.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sulfotransfer_2 PF03567.14 GAX21577.1 - 3e-06 27.3 1.7 8.8e-06 25.8 1.7 1.8 1 1 0 1 1 1 1 Sulfotransferase family Gp_dh_C PF02800.20 GAX21581.1 - 2.8e-68 228.5 0.0 4.8e-68 227.7 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX21581.1 - 2.4e-35 120.9 0.2 4.9e-35 119.9 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX21581.1 - 0.0012 18.9 0.3 0.006 16.7 0.3 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TgMIC1 PF11476.8 GAX21581.1 - 0.086 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 ADH_zinc_N PF00107.26 GAX21581.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ank_4 PF13637.6 GAX21582.1 - 3.3e-10 40.3 0.1 5.1e-05 23.7 0.0 3.5 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX21582.1 - 7.6e-10 39.2 0.0 2.4e-09 37.6 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX21582.1 - 4.4e-09 36.4 0.0 0.00026 21.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21582.1 - 0.0012 19.1 0.0 0.066 13.8 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat MRP-L20 PF12824.7 GAX21582.1 - 0.0039 17.4 0.4 0.0069 16.6 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Ank PF00023.30 GAX21582.1 - 0.042 14.3 0.0 15 6.3 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat XPC-binding PF09280.11 GAX21582.1 - 0.089 12.5 0.2 0.88 9.4 0.0 2.7 3 0 0 3 3 3 0 XPC-binding domain XRCC4 PF06632.12 GAX21582.1 - 0.43 9.4 3.7 0.64 8.8 3.2 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Endotoxin_C2 PF18449.1 GAX21584.1 - 0.053 13.9 1.6 0.94 9.9 0.5 2.4 2 0 0 2 2 2 0 Delta endotoxin Baculo_F PF12259.8 GAX21584.1 - 0.28 9.6 3.5 0.35 9.4 3.5 1.0 1 0 0 1 1 1 0 Baculovirus F protein DUF737 PF05300.11 GAX21584.1 - 0.95 9.8 12.0 0.97 9.7 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Metal_resist PF13801.6 GAX21584.1 - 4.4 7.5 7.8 0.37 11.0 1.5 2.2 2 1 0 2 2 2 0 Heavy-metal resistance Trypsin PF00089.26 GAX21586.1 - 4.4e-49 167.3 1.7 5.1e-49 167.1 1.7 1.0 1 0 0 1 1 1 1 Trypsin DUF1180 PF06679.12 GAX21587.1 - 0.15 12.5 1.6 0.17 12.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Abhydrolase_5 PF12695.7 GAX21588.1 - 1.2e-11 44.7 0.0 3.3e-07 30.2 0.0 2.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX21588.1 - 0.00058 19.2 0.0 0.0024 17.2 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX21588.1 - 0.0075 16.9 2.5 0.011 16.4 0.4 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX21588.1 - 0.06 13.0 0.0 0.93 9.1 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 GAX21588.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 GAX21588.1 - 0.12 11.9 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Peptidase_M8 PF01457.16 GAX21589.1 - 8.7e-13 47.8 0.0 1.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 GAX21589.1 - 0.0084 16.0 0.0 0.036 13.9 0.0 1.9 1 1 0 1 1 1 1 Matrixin Peptidase_M8 PF01457.16 GAX21590.1 - 2.3e-11 43.1 0.0 3.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 GAX21590.1 - 0.12 12.3 0.1 0.4 10.5 0.1 1.9 1 1 0 1 1 1 0 Matrixin TPR_2 PF07719.17 GAX21591.1 - 0.00047 20.0 1.8 2.1 8.7 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX21591.1 - 0.0019 18.7 6.3 1.3 9.6 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21591.1 - 0.0034 17.6 10.5 0.077 13.3 1.2 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX21591.1 - 0.005 17.0 5.1 2.6 8.3 0.3 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 GAX21591.1 - 0.005 17.3 8.1 18 6.3 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX21591.1 - 0.0086 16.8 8.0 16 6.7 0.1 4.7 4 2 2 6 6 6 2 Tetratricopeptide repeat FAA_hydrolase_N PF09298.11 GAX21592.1 - 0.027 14.7 0.2 0.12 12.5 0.1 2.2 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal COPIIcoated_ERV PF07970.12 GAX21593.1 - 4.6e-69 232.7 0.0 7.4e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX21593.1 - 4.5e-20 71.8 0.4 1.1e-19 70.5 0.4 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TPR_MLP1_2 PF07926.12 GAX21594.1 - 0.013 15.5 7.1 0.23 11.5 0.5 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.13 GAX21594.1 - 0.089 13.5 1.6 6.9 7.5 0.2 2.6 2 0 0 2 2 2 0 Occludin homology domain L6_membrane PF05805.12 GAX21594.1 - 0.096 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 L6 membrane protein CCDC85 PF10226.9 GAX21594.1 - 0.12 12.1 0.9 16 5.1 0.1 2.4 2 0 0 2 2 2 0 CCDC85 family Strep_SA_rep PF06696.11 GAX21594.1 - 0.4 10.7 16.1 0.058 13.4 5.7 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Prefoldin PF02996.17 GAX21594.1 - 0.55 10.2 6.3 6.2 6.8 1.1 2.5 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin_2 PF01920.20 GAX21594.1 - 0.56 10.2 11.1 1 9.4 1.2 3.3 3 0 0 3 3 3 0 Prefoldin subunit LEM PF03020.15 GAX21594.1 - 0.69 9.5 7.2 1.2 8.8 0.1 3.4 4 0 0 4 4 4 0 LEM domain FliD_N PF02465.18 GAX21594.1 - 1.4 9.7 9.1 2.7 8.7 0.1 3.4 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Abhydrolase_6 PF12697.7 GAX21596.1 - 9.8e-06 26.3 7.1 9.8e-06 26.3 7.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX21596.1 - 3.9e-05 23.4 0.3 0.2 11.3 0.3 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX21596.1 - 0.00015 21.1 0.2 0.0044 16.3 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Img2 PF05046.14 GAX21598.1 - 4.3e-18 65.4 0.0 6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Str_synth PF03088.16 GAX21599.1 - 3.9e-12 46.1 0.0 7.2e-11 42.1 0.0 2.5 1 1 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 GAX21599.1 - 1.6e-05 24.6 0.0 0.00012 21.7 0.0 2.6 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 GAX21599.1 - 0.0024 18.0 0.0 0.13 12.5 0.0 3.2 4 0 0 4 4 4 1 Arylesterase Pkinase_fungal PF17667.1 GAX21599.1 - 0.16 10.7 0.3 0.29 9.9 0.3 1.4 1 1 0 1 1 1 0 Fungal protein kinase HMG_box PF00505.19 GAX21600.1 - 2.7e-44 149.4 16.0 9.9e-23 80.3 2.4 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX21600.1 - 2.7e-33 114.4 16.3 1.1e-16 61.2 2.8 2.6 2 0 0 2 2 2 2 HMG-box domain Rtt106 PF08512.12 GAX21600.1 - 4.8e-26 91.0 0.0 1.3e-25 89.6 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like POB3_N PF17292.2 GAX21600.1 - 3.1e-13 49.9 0.0 1e-10 41.9 0.0 2.7 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 GAX21600.1 - 1.2e-12 47.6 0.1 9.4e-12 44.7 0.0 2.6 2 1 1 3 3 3 1 Structure-specific recognition protein (SSRP1) YABBY PF04690.13 GAX21600.1 - 0.57 10.7 13.5 0.093 13.3 1.5 2.8 1 1 2 3 3 3 0 YABBY protein LtrA PF06772.11 GAX21601.1 - 9.5e-07 28.3 14.5 2.5e-06 27.0 3.5 2.6 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) FAM176 PF14851.6 GAX21601.1 - 0.061 13.0 0.3 0.49 10.1 0.1 2.1 1 1 1 2 2 2 0 FAM176 family Fer4_7 PF12838.7 GAX21601.1 - 0.11 13.1 0.3 0.22 12.1 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA PF00004.29 GAX21603.1 - 2.4e-28 99.2 0.0 8.5e-28 97.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX21603.1 - 6e-08 32.4 0.1 1.4e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 GAX21603.1 - 0.00033 20.1 0.0 0.00098 18.6 0.0 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX21603.1 - 0.0032 17.5 0.1 0.033 14.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX21603.1 - 0.008 16.3 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAX21603.1 - 0.029 14.7 3.3 0.082 13.2 0.6 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX21603.1 - 0.03 14.7 0.1 0.03 14.7 0.1 3.0 4 0 0 4 4 4 0 AAA ATPase domain AAA_33 PF13671.6 GAX21603.1 - 0.073 13.2 0.1 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX21603.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 GAX21603.1 - 0.19 11.0 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 GAX21603.1 - 0.36 11.3 2.0 1.4 9.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Oxidored_molyb PF00174.19 GAX21604.1 - 2.9e-53 180.0 0.0 4.7e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAX21604.1 - 1.6e-26 93.0 1.1 6.3e-26 91.0 0.5 2.1 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 GAX21604.1 - 3.1e-12 46.4 0.0 6.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HSF_DNA-bind PF00447.17 GAX21605.1 - 1e-11 45.3 0.0 2.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding BPL_LplA_LipB PF03099.19 GAX21606.1 - 2.9e-11 43.4 0.0 4.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HSF_DNA-bind PF00447.17 GAX21607.1 - 9.7e-13 48.6 0.2 1.5e-12 47.9 0.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Tho2 PF11262.8 GAX21608.1 - 4.2e-73 246.2 0.0 4.2e-73 246.2 0.0 2.6 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 GAX21608.1 - 1.2e-38 133.1 14.1 1.5e-20 73.4 3.0 3.6 3 1 0 3 3 3 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 GAX21608.1 - 7.2e-27 93.3 0.0 1.7e-26 92.1 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit CBP4 PF07960.11 GAX21608.1 - 0.027 14.3 2.2 0.081 12.8 2.2 1.8 1 0 0 1 1 1 0 CBP4 DUF1978 PF09321.10 GAX21608.1 - 5.8 6.2 12.5 0.066 12.5 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Histone_HNS PF00816.21 GAX21608.1 - 8.9 7.2 11.2 7.4 7.5 8.7 2.2 2 0 0 2 2 2 0 H-NS histone family CHCH PF06747.13 GAX21609.1 - 0.0016 18.5 0.3 0.0032 17.6 0.3 1.6 1 0 0 1 1 1 1 CHCH domain CLZ PF16526.5 GAX21609.1 - 0.41 11.0 6.2 0.76 10.2 6.2 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 GAX21609.1 - 0.43 11.1 10.9 0.47 10.9 9.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF2570 PF10828.8 GAX21610.1 - 0.013 15.3 2.4 0.046 13.5 2.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) MCM_N PF14551.6 GAX21610.1 - 0.074 13.6 1.5 16 6.1 0.1 3.3 3 0 0 3 3 3 0 MCM N-terminal domain Tetraspanin PF00335.20 GAX21610.1 - 0.086 12.5 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Tetraspanin family Oxidored_q3 PF00499.20 GAX21610.1 - 0.093 12.4 0.6 1 9.1 0.0 2.4 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Pkinase PF00069.25 GAX21611.1 - 2.7e-37 128.6 0.1 5.6e-37 127.5 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21611.1 - 1.1e-13 51.1 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 GAX21611.1 - 0.00041 20.0 0.1 0.001 18.7 0.0 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 GAX21611.1 - 0.00099 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 GAX21611.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PqiA PF04403.13 GAX21612.1 - 1.6e-07 31.2 16.2 1.3e-06 28.4 3.0 3.2 3 0 0 3 3 3 2 Paraquat-inducible protein A zf-ACC PF17848.1 GAX21612.1 - 0.012 15.7 0.8 0.023 14.7 0.8 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Glyco_transf_22 PF03901.17 GAX21613.1 - 2.5e-38 132.4 16.8 3.3e-38 132.0 16.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Eapp_C PF10238.9 GAX21614.1 - 0.094 12.8 0.8 0.78 9.8 0.8 2.0 1 1 0 1 1 1 0 E2F-associated phosphoprotein AAA PF00004.29 GAX21615.1 - 1.4e-35 122.6 0.0 2.6e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX21615.1 - 9.1e-06 26.0 0.0 0.00018 21.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 GAX21615.1 - 2.4e-05 24.0 0.0 6.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX21615.1 - 2.8e-05 24.6 0.0 0.00014 22.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 GAX21615.1 - 0.00014 22.0 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX21615.1 - 0.00018 21.5 0.0 0.00078 19.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX21615.1 - 0.00094 18.6 0.1 0.0031 16.9 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 GAX21615.1 - 0.0013 18.5 0.1 0.0078 16.0 0.0 2.0 1 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 GAX21615.1 - 0.0014 18.6 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 GAX21615.1 - 0.0032 18.0 0.2 0.022 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAX21615.1 - 0.0052 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 GAX21615.1 - 0.0078 15.9 0.0 0.062 13.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAX21615.1 - 0.0096 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 GAX21615.1 - 0.02 15.3 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Adeno_IVa2 PF02456.15 GAX21615.1 - 0.024 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_25 PF13481.6 GAX21615.1 - 0.033 13.8 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAX21615.1 - 0.042 13.8 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 GAX21615.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAX21615.1 - 0.071 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAX21615.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 GAX21615.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 GAX21615.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Syntaxin-6_N PF09177.11 GAX21616.1 - 0.038 14.5 0.5 25 5.5 0.0 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Ntox15 PF15604.6 GAX21616.1 - 0.13 12.4 0.1 0.47 10.6 0.0 1.8 1 1 0 1 1 1 0 Novel toxin 15 CTK3_C PF12350.8 GAX21616.1 - 1 9.5 2.8 25 5.1 0.2 2.6 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus TspO_MBR PF03073.15 GAX21617.1 - 4.1e-12 46.3 13.0 4.1e-12 46.3 13.0 1.8 1 1 1 2 2 2 1 TspO/MBR family DUF5541 PF17695.1 GAX21619.1 - 0.04 14.3 0.0 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5541) Pkinase_Tyr PF07714.17 GAX21620.1 - 3.2e-15 56.1 0.0 4.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX21620.1 - 1.1e-14 54.5 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 GAX21620.1 - 0.032 13.9 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 SURF4 PF02077.15 GAX21620.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 SURF4 family Cation_efflux PF01545.21 GAX21622.1 - 9.4e-16 58.1 7.1 1.3e-15 57.6 7.1 1.2 1 0 0 1 1 1 1 Cation efflux family SRTM1 PF15872.5 GAX21622.1 - 0.0069 16.5 2.5 1.2 9.3 0.1 2.9 2 0 0 2 2 2 2 Serine-rich and transmembrane domain-containing protein 1 Ribosomal_L22e PF01776.17 GAX21623.1 - 9.7e-40 135.3 0.2 1.3e-39 134.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family T4_Gp59_N PF08993.10 GAX21623.1 - 0.032 14.7 0.6 0.06 13.8 0.3 1.5 1 1 1 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase Fasciclin PF02469.22 GAX21623.1 - 0.035 14.3 0.3 0.16 12.2 0.2 1.9 1 1 1 2 2 2 0 Fasciclin domain Thr_synth_N PF14821.6 GAX21624.1 - 5.2e-27 93.9 0.0 3.2e-26 91.4 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 GAX21624.1 - 3.4e-14 52.9 0.0 1.7e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trypsin PF00089.26 GAX21625.1 - 1.5e-30 106.7 0.0 3e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX21625.1 - 0.0087 17.0 0.0 0.022 15.7 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain RR_TM4-6 PF06459.12 GAX21625.1 - 3.2 7.5 6.4 4.5 7.0 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NHL PF01436.21 GAX21626.1 - 0.27 11.3 3.6 2.3 8.4 0.0 3.9 3 0 0 3 3 3 0 NHL repeat Cation_efflux PF01545.21 GAX21627.1 - 1.2e-16 61.0 0.0 4e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 Cation efflux family GHMP_kinases_C PF08544.13 GAX21628.1 - 6.3e-16 58.5 0.3 1.6e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAX21628.1 - 2.6e-08 34.0 1.1 2.6e-08 34.0 1.1 2.4 2 1 0 2 2 2 1 GHMP kinases N terminal domain Ntox34 PF15606.6 GAX21628.1 - 0.029 14.5 0.1 0.087 13.0 0.1 1.8 1 1 1 2 2 2 0 Bacterial toxin 34 CSN8_PSD8_EIF3K PF10075.9 GAX21629.1 - 0.055 13.4 0.0 0.07 13.1 0.0 1.1 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family DUF4336 PF14234.6 GAX21631.1 - 1.2e-14 54.2 0.0 2.6e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) TPR_2 PF07719.17 GAX21633.1 - 0.007 16.4 0.5 0.029 14.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX21633.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21633.1 - 0.051 13.9 0.3 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2140 PF09911.9 GAX21633.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) TPR_10 PF13374.6 GAX21633.1 - 0.13 12.2 1.5 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat UbiA PF01040.18 GAX21634.1 - 7.4e-26 91.0 15.5 7.4e-26 91.0 15.5 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family PPR_2 PF13041.6 GAX21635.1 - 1.5e-34 118.0 0.2 6.1e-08 32.7 0.0 7.8 6 1 1 7 7 7 6 PPR repeat family PPR_3 PF13812.6 GAX21635.1 - 3e-21 75.3 1.1 2.5e-06 27.5 0.0 7.7 5 2 3 8 8 8 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX21635.1 - 4.4e-20 71.1 0.0 4.5e-06 26.3 0.0 9.3 8 1 1 9 9 9 3 PPR repeat PPR PF01535.20 GAX21635.1 - 5.7e-20 70.1 5.3 0.00019 21.4 0.0 9.5 11 1 0 11 11 11 4 PPR repeat PPR_long PF17177.4 GAX21635.1 - 1.7e-07 30.8 2.1 0.028 13.8 0.1 4.5 3 2 1 5 5 5 2 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 GAX21635.1 - 0.0027 17.6 0.0 0.31 10.9 0.0 3.8 3 1 0 3 3 3 1 Region in Clathrin and VPS TPR_14 PF13428.6 GAX21635.1 - 0.054 14.3 0.1 2.2 9.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ENT PF03735.14 GAX21635.1 - 0.08 13.0 0.5 27 4.9 0.0 3.6 4 1 1 5 5 5 0 ENT domain Ank_2 PF12796.7 GAX21636.1 - 1.3e-17 64.2 0.7 7.6e-06 26.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX21636.1 - 4.5e-16 58.7 1.4 6e-06 26.4 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21636.1 - 1.1e-10 40.7 5.3 0.037 14.6 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 GAX21636.1 - 1.6e-10 41.3 1.8 2.8e-05 24.6 0.1 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 GAX21636.1 - 9.5e-10 38.1 14.0 9.5e-10 38.1 14.0 1.7 2 0 0 2 2 2 1 Ion transport protein Ank PF00023.30 GAX21636.1 - 9.5e-09 35.3 8.3 0.036 14.5 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat DUF4618 PF15397.6 GAX21636.1 - 0.017 14.5 4.9 0.03 13.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CemA PF03040.14 GAX21636.1 - 0.019 14.9 0.4 0.019 14.9 0.4 1.7 2 0 0 2 2 2 0 CemA family PAP2_C PF14360.6 GAX21637.1 - 1.7e-18 66.9 3.7 1.7e-18 66.9 3.7 4.0 3 1 1 4 4 4 1 PAP2 superfamily C-terminal PAP2 PF01569.21 GAX21637.1 - 0.00046 20.0 0.4 0.00046 20.0 0.4 3.8 4 1 1 5 5 5 1 PAP2 superfamily PAP2_3 PF14378.6 GAX21637.1 - 0.0014 18.3 7.3 0.0014 18.3 7.3 4.3 3 2 2 5 5 5 1 PAP2 superfamily DUF2207 PF09972.9 GAX21637.1 - 4.2 6.0 8.6 0.91 8.2 1.9 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Response_reg PF00072.24 GAX21638.1 - 3.2e-20 72.4 0.0 1.9e-17 63.4 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 GAX21638.1 - 4.2e-07 29.9 0.1 1.4e-06 28.3 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 GAX21638.1 - 4.4e-05 23.9 0.0 9.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M43 PF05572.13 GAX21639.1 - 6.9e-14 52.0 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 GAX21639.1 - 0.0013 18.4 0.1 0.0026 17.5 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX21639.1 - 0.0018 18.8 0.1 0.0034 17.9 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX21639.1 - 0.0019 18.1 0.1 0.003 17.4 0.1 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 GAX21639.1 - 0.002 18.3 1.1 0.005 17.0 1.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 GAX21639.1 - 0.012 14.6 2.0 0.025 13.6 2.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 GAX21639.1 - 0.021 14.5 0.9 0.042 13.5 0.9 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 GAX21639.1 - 0.21 11.2 1.5 0.38 10.3 1.5 1.6 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.5 GAX21639.1 - 0.68 9.1 3.4 1.2 8.3 3.4 1.3 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 GAX21639.1 - 0.83 8.2 3.3 1.3 7.5 2.9 1.5 2 0 0 2 2 2 0 Putative peptidase family IF-2B PF01008.17 GAX21640.1 - 3e-63 213.7 0.0 3.6e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 GAX21640.1 - 0.014 15.3 0.1 3.3 7.6 0.1 2.4 2 0 0 2 2 2 0 DeoR C terminal sensor domain RraA-like PF03737.15 GAX21641.1 - 1.2e-29 103.4 0.1 1.7e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA PaREP1 PF05942.11 GAX21643.1 - 0.069 13.1 1.3 3.9 7.4 0.1 2.5 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family Drc1-Sld2 PF11719.8 GAX21645.1 - 1.9e-10 40.9 6.2 6.6e-05 22.6 0.9 3.8 3 0 0 3 3 3 3 DNA replication and checkpoint protein GAS PF13851.6 GAX21645.1 - 2.8 7.2 10.4 0.72 9.2 0.5 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Ribosomal_L6e PF01159.19 GAX21646.1 - 6.4e-37 126.5 0.1 8.4e-37 126.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.29 GAX21646.1 - 0.055 13.4 0.2 0.29 11.1 0.3 2.1 2 0 0 2 2 2 0 KOW motif MFS_1 PF07690.16 GAX21647.1 - 1.8e-17 63.3 21.3 1.8e-17 63.3 21.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX21647.1 - 8.7e-06 24.9 0.6 8.7e-06 24.9 0.6 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Vasohibin PF14822.6 GAX21647.1 - 0.033 13.4 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Vasohibin HH_signal PF01085.18 GAX21647.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain UCR_Fe-S_N PF10399.9 GAX21647.1 - 0.35 10.3 2.7 1.5 8.2 0.6 3.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF1129 PF06570.11 GAX21647.1 - 0.96 8.9 8.6 0.32 10.5 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) NAD_kinase PF01513.21 GAX21649.1 - 5.7e-11 42.2 0.0 2.4e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 GAX21649.1 - 0.0089 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain AhpC-TSA PF00578.21 GAX21650.1 - 8.4e-27 93.6 0.0 1.3e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX21650.1 - 8.9e-10 38.4 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAX21650.1 - 8.4e-06 25.5 0.4 4.9e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin DUF1989 PF09347.10 GAX21651.1 - 6.6e-56 188.5 0.1 8.3e-56 188.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) HD_4 PF13328.6 GAX21653.1 - 7.6e-46 155.7 0.1 1.7e-45 154.6 0.1 1.6 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 GAX21653.1 - 1.6e-25 89.6 0.0 5.8e-25 87.9 0.0 2.0 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins TGS PF02824.21 GAX21653.1 - 9.8e-15 54.4 0.0 5.1e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 TGS domain ACT_4 PF13291.6 GAX21653.1 - 6.2e-10 39.5 1.9 9e-10 39.0 0.7 2.0 2 0 0 2 2 2 1 ACT domain HD PF01966.22 GAX21653.1 - 1.5e-08 34.9 0.1 4.6e-08 33.3 0.1 1.9 1 0 0 1 1 1 1 HD domain Ub-Mut7C PF14451.6 GAX21653.1 - 0.0015 18.4 0.2 0.012 15.4 0.0 2.7 3 0 0 3 3 3 1 Mut7-C ubiquitin ThiS PF02597.20 GAX21653.1 - 0.0016 19.0 0.0 0.014 16.0 0.0 2.7 2 1 1 3 3 3 1 ThiS family HMG_box PF00505.19 GAX21654.1 - 1.8e-27 95.5 10.0 9.3e-16 58.0 0.2 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX21654.1 - 4.8e-18 65.5 9.3 6.5e-09 36.3 0.2 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 GAX21654.1 - 0.00034 20.5 6.6 0.0087 16.0 2.8 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box 5 Ccdc124 PF06244.12 GAX21654.1 - 0.05 14.2 10.6 0.64 10.6 0.2 3.4 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 Abhydrolase_6 PF12697.7 GAX21655.1 - 6.1e-05 23.7 1.1 0.00014 22.6 1.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 GAX21655.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 GAX21655.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 3) Granulin PF00396.18 GAX21655.1 - 0.093 13.1 6.9 0.23 11.9 6.9 1.6 1 0 0 1 1 1 0 Granulin Palm_thioest PF02089.15 GAX21655.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Kelch_1 PF01344.25 GAX21655.1 - 0.39 10.4 2.9 0.64 9.6 0.2 2.6 3 0 0 3 3 3 0 Kelch motif Peptidase_M11 PF05548.11 GAX21656.1 - 1.2e-12 47.6 4.7 1.8e-11 43.8 4.7 2.1 1 1 0 1 1 1 1 Gametolysin peptidase M11 Metallopep PF12044.8 GAX21656.1 - 1.5e-05 23.9 1.4 2.7e-05 23.0 1.4 1.3 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 GAX21656.1 - 0.00046 20.7 0.1 0.0016 19.0 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX21656.1 - 0.013 15.7 0.2 0.031 14.4 0.2 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 GAX21656.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 GAX21656.1 - 0.097 11.6 3.9 0.18 10.7 3.9 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 GAX21656.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Met-zincin FAM176 PF14851.6 GAX21656.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Reprolysin_4 PF13583.6 GAX21656.1 - 0.34 10.5 3.0 0.15 11.7 0.4 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Pup PF05639.11 GAX21656.1 - 0.96 10.4 2.7 0.63 11.0 0.4 1.8 2 0 0 2 2 2 0 Pup-like protein Pkinase PF00069.25 GAX21657.1 - 4.1e-54 183.7 0.0 4.7e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21657.1 - 2.2e-26 92.7 0.0 2.8e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX21657.1 - 9.3e-07 28.4 0.0 8.3e-06 25.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAX21657.1 - 0.039 12.9 0.0 0.075 12.0 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 GAX21657.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Imm7 PF15585.6 GAX21657.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 7 RIO1 PF01163.22 GAX21657.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 GAX21658.1 - 4.1e-48 161.9 3.8 1.6e-13 51.0 0.3 5.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX21658.1 - 1.4e-39 133.9 8.8 1.3e-06 28.9 0.0 8.2 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX21658.1 - 1.8e-38 126.1 7.1 0.00011 22.4 0.1 10.6 11 1 1 12 12 12 9 Ankyrin repeat Ank PF00023.30 GAX21658.1 - 3.7e-31 106.2 13.3 0.00049 20.4 0.0 10.5 9 2 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 GAX21658.1 - 3.5e-28 97.3 12.7 5.7e-09 36.1 0.1 7.8 1 1 7 9 9 9 9 Ankyrin repeats (many copies) INTS5_C PF14838.6 GAX21658.1 - 0.054 12.1 0.1 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus zf-MYND PF01753.18 GAX21659.1 - 2.9e-06 27.3 16.7 5.7e-06 26.3 16.7 1.5 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.25 GAX21660.1 - 5.9e-59 199.6 0.0 9.4e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX21660.1 - 7.6e-33 112.5 0.0 1.6e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX21660.1 - 6.4e-26 91.2 0.0 1.1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX21660.1 - 5.7e-07 29.7 0.0 0.0086 16.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family EF-hand_7 PF13499.6 GAX21660.1 - 7.6e-07 29.5 0.9 0.21 12.1 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain pair Kinase-like PF14531.6 GAX21660.1 - 1.3e-05 24.6 0.0 4.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAX21660.1 - 0.00027 20.4 0.0 0.00063 19.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.21 GAX21661.1 - 1.5e-05 25.3 2.2 0.0027 18.0 0.0 3.3 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD V_ATPase_I PF01496.19 GAX21661.1 - 3 5.7 11.4 3.6 5.4 11.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family P16-Arc PF04699.14 GAX21661.1 - 6 7.3 10.3 0.36 11.3 0.7 2.5 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Cob_adeno_trans PF01923.18 GAX21661.1 - 8 6.6 8.3 1.2 9.2 3.4 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase TauE PF01925.19 GAX21662.1 - 6.7e-43 147.0 23.7 8.7e-43 146.6 23.7 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2076 PF09849.9 GAX21662.1 - 0.036 14.1 1.1 0.19 11.8 0.9 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) LRR_1 PF00560.33 GAX21664.1 - 0.096 13.3 0.3 0.62 10.8 0.1 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat Abhydrolase_6 PF12697.7 GAX21666.1 - 3.7e-08 34.2 0.2 6e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX21666.1 - 0.13 11.5 0.0 4.1 6.6 0.0 2.6 2 1 0 2 2 2 0 Serine aminopeptidase, S33 GSDH PF07995.11 GAX21668.1 - 0.00013 21.4 0.3 0.00054 19.4 0.3 2.1 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase HMG_box PF00505.19 GAX21669.1 - 2e-30 105.0 16.0 4.1e-19 68.8 3.4 2.7 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX21669.1 - 1.1e-21 77.2 15.0 1.3e-11 44.9 3.5 2.5 2 1 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 GAX21669.1 - 2.4 8.2 18.0 0.68 9.9 3.1 3.7 3 1 1 4 4 4 0 HMG (high mobility group) box 5 Ccdc124 PF06244.12 GAX21669.1 - 4 8.0 18.7 0.23 12.0 6.4 3.4 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 VitD-bind_III PF09164.10 GAX21669.1 - 5 7.2 5.8 3 7.9 0.1 3.0 2 1 0 3 3 3 0 Vitamin D binding protein, domain III DUF726 PF05277.12 GAX21670.1 - 7.9e-81 271.6 1.4 2e-31 109.2 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF726) G_glu_transpept PF01019.21 GAX21670.1 - 0.054 12.3 2.0 0.08 11.7 2.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Halogen_Hydrol PF10112.9 GAX21670.1 - 0.8 9.7 3.3 29 4.6 0.0 3.2 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DDR PF08841.10 GAX21670.1 - 0.89 8.5 3.4 1.6 7.7 3.4 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Phage_holin_3_6 PF07332.11 GAX21670.1 - 2 8.5 13.1 2.4 8.2 10.8 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HMG_box PF00505.19 GAX21671.1 - 4e-28 97.6 12.2 1.4e-17 63.9 1.1 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX21671.1 - 2.5e-16 60.0 12.3 7.1e-08 32.9 1.1 2.4 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 GAX21671.1 - 0.075 13.0 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 CHDNT (NUC034) domain PAP_fibrillin PF04755.12 GAX21672.1 - 4.6e-15 56.1 0.1 1e-12 48.4 0.1 2.1 1 1 0 1 1 1 1 PAP_fibrillin PQQ_2 PF13360.6 GAX21673.1 - 0.00046 19.8 0.5 0.011 15.3 0.1 2.7 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 GAX21673.1 - 0.01 15.7 0.3 0.076 13.0 0.0 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 GAX21673.1 - 2.7 8.6 15.2 0.59 10.7 0.2 4.4 5 1 0 5 5 5 0 PQQ-like domain KH_dom-like PF14714.6 GAX21674.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.4 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal E1-E2_ATPase PF00122.20 GAX21675.1 - 6.3e-40 136.6 4.1 6.3e-40 136.6 4.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAX21675.1 - 1.4e-38 133.3 0.5 2.6e-38 132.4 0.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAX21675.1 - 1.3e-09 38.3 0.0 4.7e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAX21675.1 - 0.06 13.1 1.1 0.48 10.1 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sep15_SelM PF08806.11 GAX21676.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Sep15/SelM redox domain PsbP PF01789.16 GAX21677.1 - 4.3e-15 56.2 0.0 5.4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 PsbP Peptidase_S41 PF03572.18 GAX21681.1 - 3.6e-40 137.2 0.0 9.2e-40 135.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GAX21681.1 - 2.1e-08 33.9 0.1 6e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX21681.1 - 5.4e-06 26.6 0.1 1.6e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX21681.1 - 0.0035 17.7 0.0 0.0091 16.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain LSDAT_prok PF18171.1 GAX21681.1 - 0.092 12.0 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote DUF1176 PF06674.11 GAX21682.1 - 0.075 12.5 0.2 0.09 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Yip1 PF04893.17 GAX21683.1 - 2.7e-11 43.5 7.7 4.3e-11 42.8 7.7 1.4 1 0 0 1 1 1 1 Yip1 domain Ycf34 PF10718.9 GAX21683.1 - 0.84 10.4 4.4 9.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 adh_short PF00106.25 GAX21684.1 - 1.1e-29 103.3 0.0 1.1e-25 90.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX21684.1 - 1.4e-17 64.1 0.0 2.5e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX21684.1 - 9.3e-07 28.9 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Sec66 PF09802.9 GAX21684.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 adh_short PF00106.25 GAX21685.1 - 1.6e-29 102.7 0.0 2.6e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX21685.1 - 2.8e-18 66.3 0.0 1.7e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX21685.1 - 4.3e-05 23.5 0.0 6.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2344 PF10105.9 GAX21685.1 - 0.011 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Epimerase PF01370.21 GAX21685.1 - 0.071 12.6 0.0 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAX21686.1 - 1.2e-31 109.7 0.0 5.3e-23 81.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX21686.1 - 5.4e-22 78.5 0.0 8e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX21686.1 - 0.0003 20.8 0.0 0.00043 20.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF4477 PF14780.6 GAX21688.1 - 0.064 12.9 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) TALPID3 PF15324.6 GAX21689.1 - 0.69 7.5 9.3 0.89 7.1 9.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Med13_C PF06333.12 GAX21690.1 - 0.46 9.7 5.9 0.64 9.2 5.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Rib_recp_KP_reg PF05104.12 GAX21690.1 - 1.2 10.2 13.4 2 9.5 13.4 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region PT PF04886.12 GAX21691.1 - 4.1e-05 23.0 48.4 4.1e+02 0.6 0.9 4.3 2 1 0 2 2 2 0 PT repeat SET PF00856.28 GAX21693.1 - 1.5e-13 51.5 0.1 6.9e-07 29.8 0.0 4.3 2 2 0 2 2 2 2 SET domain SET PF00856.28 GAX21694.1 - 9.7e-14 52.1 0.0 5.1e-07 30.2 0.0 3.3 2 1 0 2 2 2 2 SET domain SAF PF08666.12 GAX21694.1 - 0.16 12.6 0.3 9.6 6.9 0.0 3.1 3 0 0 3 3 3 0 SAF domain Kinesin PF00225.23 GAX21696.1 - 2.1e-103 345.8 0.1 1e-102 343.5 0.1 2.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX21696.1 - 6e-30 104.2 13.6 3.9e-29 101.5 0.0 4.2 3 1 1 4 4 4 2 Microtubule binding TPR_MLP1_2 PF07926.12 GAX21696.1 - 0.012 15.7 3.0 0.012 15.7 3.0 10.6 6 2 3 10 10 10 0 TPR/MLP1/MLP2-like protein DUF846 PF05832.12 GAX21697.1 - 1.2e-47 161.4 10.3 1.5e-47 161.1 10.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Phage_holin_2_4 PF16082.5 GAX21697.1 - 0.081 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4191 PF13829.6 GAX21697.1 - 2 7.7 6.6 0.2 11.0 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) SpoU_methylase PF00588.19 GAX21698.1 - 1.1e-05 25.6 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family PC-Esterase PF13839.6 GAX21698.1 - 0.034 13.9 0.5 0.072 12.8 0.5 1.4 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p NmrA PF05368.13 GAX21699.1 - 6.4e-24 84.8 0.0 8.2e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAX21699.1 - 7.7e-11 42.2 0.1 1.6e-10 41.1 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAX21699.1 - 0.0052 17.1 0.0 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAX21699.1 - 0.048 13.1 0.1 0.092 12.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 GAX21699.1 - 0.06 12.3 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 GAX21699.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 GAX21699.1 - 0.11 12.9 0.1 0.27 11.7 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DENN PF02141.21 GAX21700.1 - 4e-26 92.1 2.0 1.6e-25 90.2 2.0 2.0 1 1 0 1 1 1 1 DENN (AEX-3) domain ENTH PF01417.20 GAX21700.1 - 5.1e-12 45.9 0.0 2e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 ENTH domain dDENN PF03455.19 GAX21700.1 - 0.0023 17.9 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 dDENN domain PUB PF09409.10 GAX21701.1 - 7.5e-12 45.0 0.0 2.4e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 PUB domain ECH_2 PF16113.5 GAX21701.1 - 0.0019 17.8 1.3 0.0032 17.0 1.3 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF445 PF04286.12 GAX21701.1 - 0.017 15.0 2.0 0.023 14.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Z1 PF10593.9 GAX21701.1 - 0.15 11.6 1.0 0.23 10.9 1.0 1.3 1 0 0 1 1 1 0 Z1 domain Fig1 PF12351.8 GAX21701.1 - 0.18 11.7 0.5 0.63 9.9 0.6 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 SPACA9 PF15120.6 GAX21701.1 - 0.47 10.2 6.3 0.8 9.5 6.3 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 HIP1_clath_bdg PF16515.5 GAX21701.1 - 1.7 9.3 15.0 3.8 8.2 15.0 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4404 PF14357.6 GAX21701.1 - 6.3 7.5 12.1 0.29 11.8 1.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) CRCB PF02537.15 GAX21702.1 - 2.6e-21 75.7 8.3 5.7e-10 39.4 5.1 3.3 3 0 0 3 3 3 3 CrcB-like protein, Camphor Resistance (CrcB) GDPD_2 PF13653.6 GAX21702.1 - 0.15 12.6 0.2 9.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family ArfGap PF01412.18 GAX21703.1 - 2.7e-32 111.3 0.0 6.2e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 GAX21703.1 - 2.8e-13 50.3 0.0 5.9e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 PH domain BAR_3 PF16746.5 GAX21703.1 - 1.6e-11 44.4 0.2 1.1e-06 28.6 0.1 2.4 2 0 0 2 2 2 2 BAR domain of APPL family SBP PF03110.14 GAX21703.1 - 0.08 13.3 0.0 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 SBP domain DUF2780 PF11075.8 GAX21704.1 - 1.6 8.9 0.0 1.6 8.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function VcgC/VcgE (DUF2780) AIM5 PF17050.5 GAX21704.1 - 2.4 9.1 7.2 1.8 9.4 0.0 4.5 4 0 0 4 4 4 0 Altered inheritance of mitochondria 5 TelA PF05816.11 GAX21705.1 - 0.00099 18.3 1.3 0.0053 15.9 0.0 1.9 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) HBM PF16591.5 GAX21705.1 - 0.011 15.2 2.1 0.026 13.9 0.2 1.9 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF948 PF06103.11 GAX21705.1 - 0.029 14.6 0.9 0.029 14.6 0.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 GAX21705.1 - 0.033 13.1 9.1 0.15 10.9 9.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2564 PF10819.8 GAX21705.1 - 0.048 14.1 0.5 0.048 14.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) SRP54_N PF02881.19 GAX21705.1 - 0.066 13.4 1.5 0.42 10.9 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain DUF1664 PF07889.12 GAX21705.1 - 0.071 13.2 4.5 0.079 13.0 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SPACA9 PF15120.6 GAX21705.1 - 0.093 12.5 0.2 0.15 11.8 0.2 1.4 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 MukF_M PF17192.4 GAX21705.1 - 0.12 12.2 0.6 0.16 11.7 0.6 1.3 1 1 0 1 1 1 0 MukF middle domain DUF1666 PF07891.12 GAX21705.1 - 0.14 11.9 0.6 0.2 11.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) DUF1759 PF03564.15 GAX21705.1 - 0.14 12.1 1.5 0.26 11.2 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) TMPIT PF07851.13 GAX21705.1 - 0.25 10.6 2.8 0.19 11.0 1.4 1.4 1 1 0 1 1 1 0 TMPIT-like protein Tektin PF03148.14 GAX21705.1 - 0.28 9.9 4.1 1.9 7.1 0.5 2.1 2 0 0 2 2 2 0 Tektin family Laminin_II PF06009.12 GAX21705.1 - 0.34 10.9 8.1 1.7 8.7 4.4 2.6 1 1 1 2 2 2 0 Laminin Domain II IZUMO PF15005.6 GAX21705.1 - 0.39 11.2 2.0 0.29 11.7 0.5 1.5 2 0 0 2 2 1 0 Izumo sperm-egg fusion, Ig domain-associated AAA_13 PF13166.6 GAX21705.1 - 0.42 9.2 8.7 0.021 13.5 1.5 1.7 1 1 1 2 2 2 0 AAA domain ISG65-75 PF11727.8 GAX21705.1 - 0.64 9.2 11.2 0.99 8.6 2.2 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein BRE1 PF08647.11 GAX21705.1 - 0.68 10.0 10.4 0.12 12.5 2.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase KxDL PF10241.9 GAX21705.1 - 0.76 10.1 4.3 0.25 11.6 1.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF2959 PF11172.8 GAX21705.1 - 0.89 9.7 7.2 1.1 9.4 0.6 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF2959) DUF724 PF05266.14 GAX21705.1 - 0.94 9.3 4.8 0.87 9.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) YvbH_ext PF11724.8 GAX21705.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.2 2 1 1 3 3 3 0 YvbH-like oligomerisation region TMF_DNA_bd PF12329.8 GAX21705.1 - 1.4 8.9 15.0 0.11 12.5 4.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 GAX21705.1 - 4.5 7.8 12.0 35 4.9 11.7 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 GAX21705.1 - 5.5 6.2 8.2 1.6 8.0 2.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Goodbye PF17109.5 GAX21705.1 - 8.3 6.9 8.1 39 4.7 0.2 3.6 2 1 2 4 4 4 0 fungal STAND N-terminal Goodbye domain SH3_12 PF18129.1 GAX21706.1 - 0.014 15.5 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Xrn1 SH3-like domain Lycopene_cycl PF05834.12 GAX21707.1 - 4.6e-60 203.7 0.0 6.3e-59 199.9 0.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAX21707.1 - 0.081 12.2 0.0 7.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Mito_carr PF00153.27 GAX21708.1 - 4.1e-68 225.4 0.3 5.6e-24 83.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX21708.1 - 0.001 18.3 0.1 7.4 5.6 0.0 3.5 3 0 0 3 3 3 3 Gammaproteobacterial serine protease Met_10 PF02475.16 GAX21709.1 - 1.2e-25 90.4 0.0 1.7e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GAX21709.1 - 1.2e-05 26.0 0.0 2.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX21709.1 - 1.9e-05 24.2 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 GAX21709.1 - 7.4e-05 22.5 0.0 0.00019 21.1 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PrmA PF06325.13 GAX21709.1 - 0.00056 19.4 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 GAX21709.1 - 0.0076 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 GAX21709.1 - 0.0076 16.0 0.0 0.017 15.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX21709.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 GAX21709.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_11 PF08241.12 GAX21709.1 - 0.013 16.1 0.0 0.058 14.0 0.0 2.1 2 0 0 2 2 1 0 Methyltransferase domain DNA_methylase PF00145.17 GAX21709.1 - 0.048 13.0 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF604 PF04646.12 GAX21709.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 DUF3598 PF12204.8 GAX21710.1 - 9.8e-08 31.8 0.3 1.2e-05 25.0 0.0 2.7 4 0 0 4 4 4 2 Domain of unknown function (DUF3598) PhoLip_ATPase_C PF16212.5 GAX21711.1 - 9.6e-50 169.7 8.8 9.6e-50 169.7 8.8 2.3 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAX21711.1 - 1.6e-13 50.2 0.2 1.6e-13 50.2 0.2 3.2 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAX21711.1 - 2e-10 41.3 0.2 0.0002 21.7 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX21711.1 - 3.3e-05 23.9 0.0 0.00019 21.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAX21711.1 - 8.1e-05 22.2 0.4 0.0099 15.4 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAX21711.1 - 0.028 14.2 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FoP_duplication PF13865.6 GAX21714.1 - 6.1e-15 55.5 18.0 6.1e-15 55.5 18.0 2.2 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 MAJIN PF15077.6 GAX21714.1 - 3.5 7.4 13.4 4.7 6.9 13.4 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Zip PF02535.22 GAX21714.1 - 9.7 5.3 5.5 12 5.0 5.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GalKase_gal_bdg PF10509.9 GAX21715.1 - 1.7e-19 69.1 0.8 4e-19 67.9 0.2 1.9 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 GAX21715.1 - 4e-14 52.7 0.1 6e-13 49.0 0.0 2.6 3 0 0 3 3 3 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAX21715.1 - 1.8e-09 37.7 0.5 5.7e-09 36.1 0.4 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain TLD PF07534.16 GAX21716.1 - 1.2e-17 64.4 0.0 3.6e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 TLD PP2C PF00481.21 GAX21717.1 - 4.8e-45 154.2 0.3 6.5e-45 153.8 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX21717.1 - 2.9e-08 33.6 0.4 6.4e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C Kinesin PF00225.23 GAX21718.1 - 1.5e-99 333.1 0.0 1.5e-99 333.1 0.0 2.8 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAX21718.1 - 4.7e-26 91.5 0.0 1.9e-25 89.5 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding CP12 PF02672.15 GAX21718.1 - 2.2 9.1 10.6 3.7 8.4 4.5 4.5 1 1 2 3 3 3 0 CP12 domain DUF5384 PF17358.2 GAX21719.1 - 0.011 15.8 3.2 0.011 15.8 3.2 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5384) FGAR-AT_N PF18076.1 GAX21719.1 - 0.042 13.8 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal AidB_N PF18158.1 GAX21719.1 - 0.07 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Adaptive response protein AidB N-terminal domain Phytochelatin PF05023.14 GAX21720.1 - 1.8e-78 262.6 0.0 2.3e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase LRR_6 PF13516.6 GAX21721.1 - 1.2e-12 46.8 5.6 0.043 13.9 0.0 7.6 7 0 0 7 7 7 5 Leucine Rich repeat LRR_8 PF13855.6 GAX21721.1 - 0.2 11.4 10.1 4.2 7.2 0.4 4.8 4 1 1 5 5 5 0 Leucine rich repeat ROK PF00480.20 GAX21722.1 - 1.8e-42 145.8 0.0 2.1e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 GAX21722.1 - 0.0014 17.7 1.6 0.0094 15.0 0.4 2.5 3 0 0 3 3 3 1 Glucokinase Creb_binding PF09030.10 GAX21722.1 - 0.042 14.5 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Creb binding baeRF_family10 PF18854.1 GAX21722.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Polyketide_cyc PF03364.20 GAX21723.1 - 1.8e-08 34.7 0.4 1.3e-07 31.9 0.4 2.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAX21723.1 - 0.0007 19.9 0.0 0.023 14.9 0.0 2.6 3 0 0 3 3 3 1 Polyketide cyclase / dehydrase and lipid transport 2OG-FeII_Oxy_3 PF13640.6 GAX21724.1 - 9.8e-10 39.2 0.0 2.5e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RVT_thumb PF06817.14 GAX21724.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase thumb domain bMG3 PF11974.8 GAX21725.1 - 9.9e-07 28.7 0.3 0.058 13.4 0.1 2.8 2 0 0 2 2 2 2 Bacterial alpha-2-macroglobulin MG3 domain SdrD_B PF17210.3 GAX21725.1 - 3.5e-05 24.0 5.6 0.065 13.5 0.1 3.6 3 0 0 3 3 3 2 SdrD B-like domain CarboxypepD_reg PF13620.6 GAX21725.1 - 0.0013 18.9 1.7 0.22 11.8 0.1 3.1 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain Big_6 PF17936.1 GAX21725.1 - 0.0026 18.0 2.0 0.081 13.2 0.2 3.0 2 0 0 2 2 2 1 Bacterial Ig domain Noelin-1 PF12308.8 GAX21726.1 - 0.03 14.3 0.2 0.03 14.3 0.2 1.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein Acetyltransf_1 PF00583.25 GAX21728.1 - 7.9e-14 51.9 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX21728.1 - 1.4e-07 31.5 0.3 1.7e-07 31.2 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX21728.1 - 1.6e-07 31.6 0.0 2.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX21728.1 - 8.8e-06 25.6 0.1 1.8e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAX21728.1 - 0.0002 21.4 0.2 0.00039 20.5 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAX21728.1 - 0.034 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 GAX21728.1 - 0.036 13.5 1.5 0.059 12.8 1.5 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase DUF2511 PF10709.9 GAX21728.1 - 0.15 12.3 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2511) Cyclin_N PF00134.23 GAX21729.1 - 2.8e-15 56.2 0.3 4.9e-15 55.4 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX21729.1 - 9.3e-07 29.0 1.0 9.3e-07 29.0 1.0 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain UL16 PF17622.2 GAX21730.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral unique long protein 16 Dak1 PF02733.17 GAX21731.1 - 8e-99 330.4 1.7 8e-99 330.4 1.7 1.8 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 GAX21731.1 - 7.4e-38 130.2 4.0 7.4e-38 130.2 4.0 2.5 3 0 0 3 3 3 1 DAK2 domain Pox_MCEL PF03291.16 GAX21735.1 - 4.1e-41 141.2 0.0 9e-20 71.0 0.0 3.2 3 0 0 3 3 3 3 mRNA capping enzyme Methyltransf_25 PF13649.6 GAX21735.1 - 4.5e-10 40.1 0.0 4.2e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GAX21735.1 - 9.6e-09 35.2 0.0 1.6e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX21735.1 - 1.4e-08 35.3 0.3 0.0018 18.9 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAX21735.1 - 1.4e-08 35.4 0.1 1.5e-07 32.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX21735.1 - 4.4e-05 23.4 0.0 9.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX21735.1 - 0.042 13.2 0.1 5.7 6.2 0.0 2.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FTR1 PF03239.14 GAX21736.1 - 2.9e-06 26.7 8.0 1.6e-05 24.2 8.0 2.3 1 1 0 1 1 1 1 Iron permease FTR1 family Phage_holin_8 PF16931.5 GAX21736.1 - 0.58 10.1 6.0 1.5 8.8 0.6 2.5 2 0 0 2 2 2 0 Putative phage holin Pribosyl_synth PF14572.6 GAX21737.1 - 3.8e-07 30.3 0.0 5.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAX21737.1 - 2e-06 27.4 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SecE PF00584.20 GAX21738.1 - 2.5e-14 52.9 0.0 3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF5312 PF17239.2 GAX21738.1 - 0.13 10.6 0.0 0.14 10.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5312) PAP2 PF01569.21 GAX21739.1 - 1.6e-08 34.4 1.8 1.6e-08 34.4 1.8 1.9 1 1 1 2 2 2 1 PAP2 superfamily SRP14 PF02290.15 GAX21739.1 - 0.14 12.6 0.1 0.32 11.4 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Glug PF07581.12 GAX21739.1 - 6.4 7.4 7.8 8.9 7.0 0.0 3.2 4 0 0 4 4 4 0 The GLUG motif Mannitol_dh_C PF08125.13 GAX21740.1 - 8.1e-84 280.9 0.0 1.2e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 GAX21740.1 - 3.2e-37 128.0 0.0 4.7e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain LPMO_10 PF03067.15 GAX21741.1 - 2.4e-28 100.1 1.1 3.3e-28 99.7 1.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Toxin_12 PF07740.12 GAX21741.1 - 0.0017 19.0 5.5 0.0038 17.9 5.5 1.7 1 0 0 1 1 1 1 Ion channel inhibitory toxin Sugar_tr PF00083.24 GAX21742.1 - 2.9e-83 280.2 11.5 3.5e-83 280.0 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX21742.1 - 8e-25 87.5 30.9 4.3e-19 68.6 7.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF456 PF04306.13 GAX21743.1 - 5.7 7.2 8.8 0.18 12.1 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF456) COG6 PF06419.11 GAX21744.1 - 1.5e-55 188.6 17.2 2.1e-54 184.9 17.2 2.3 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 Exo70 PF03081.15 GAX21744.1 - 0.0052 15.9 6.6 0.0081 15.3 0.1 3.0 4 1 0 4 4 4 2 Exo70 exocyst complex subunit DUF713 PF05218.14 GAX21744.1 - 0.052 13.3 3.6 6.6 6.4 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF713) FKBP_C PF00254.28 GAX21745.1 - 5.5e-21 74.7 0.0 9.5e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 GAX21745.1 - 0.002 19.1 0.0 0.0053 17.7 0.0 1.7 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FemAB_like PF04339.12 GAX21746.1 - 7.4e-108 361.0 0.0 1.2e-107 360.3 0.0 1.3 1 1 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 GAX21746.1 - 8.3e-09 35.7 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain M157 PF11624.8 GAX21746.1 - 0.11 11.8 0.2 1.8 7.8 0.0 2.4 3 0 0 3 3 3 0 MHC class I-like protein M157 Varsurf_PPLC PF03490.13 GAX21747.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C Peptidase_S49 PF01343.18 GAX21748.1 - 4.4e-56 189.1 0.0 6.3e-41 139.9 0.0 3.3 2 1 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 GAX21748.1 - 0.00012 22.0 0.5 0.074 12.9 0.0 3.4 4 0 0 4 4 4 2 Clp protease SDH_sah PF01972.16 GAX21748.1 - 0.0049 15.9 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase DUF4770 PF15994.5 GAX21750.1 - 8.6 6.6 7.1 88 3.3 7.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4770) Thioredoxin PF00085.20 GAX21751.1 - 4.1e-26 91.0 0.0 2.3e-25 88.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 GAX21751.1 - 2.1e-08 34.3 0.0 5.4e-05 23.2 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX21751.1 - 4.2e-05 23.8 0.1 0.16 12.3 0.0 4.1 3 1 1 4 4 4 1 Thioredoxin-like TraF PF13728.6 GAX21751.1 - 0.0025 17.6 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GAX21751.1 - 0.018 14.8 0.1 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.6 GAX21751.1 - 0.037 14.2 0.1 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Redoxin PF08534.10 GAX21751.1 - 0.08 12.7 1.2 3.4 7.4 0.0 2.2 1 1 1 2 2 2 0 Redoxin Thioredoxin_2 PF13098.6 GAX21751.1 - 0.12 12.9 0.2 1.8 9.1 0.1 2.9 3 1 0 3 3 3 0 Thioredoxin-like domain TPR_1 PF00515.28 GAX21752.1 - 7.2e-45 149.0 18.0 3.7e-08 32.8 0.4 10.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21752.1 - 2.1e-43 143.0 25.8 7.9e-07 28.7 0.0 11.7 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_8 PF13181.6 GAX21752.1 - 8.3e-31 103.6 3.9 0.00019 21.3 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAX21752.1 - 4.5e-30 104.0 15.8 3.8e-07 30.7 0.0 8.2 5 3 3 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAX21752.1 - 1.1e-28 99.5 18.4 6.5e-07 29.8 0.0 8.5 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAX21752.1 - 7.5e-26 89.6 0.2 0.00014 21.4 0.1 9.1 5 2 4 9 9 9 7 TPR repeat ANAPC3 PF12895.7 GAX21752.1 - 1.5e-25 89.2 26.6 7e-18 64.6 3.0 6.2 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAX21752.1 - 2.4e-24 83.9 18.6 0.0033 18.1 0.0 10.4 4 2 7 11 11 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21752.1 - 2.1e-21 76.0 20.4 0.001 19.3 0.5 8.9 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 GAX21752.1 - 2.5e-19 68.2 12.6 0.033 14.6 0.2 10.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX21752.1 - 2.8e-16 58.3 6.0 0.002 18.0 0.0 7.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAX21752.1 - 1.7e-13 50.5 14.6 0.053 13.7 0.1 7.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX21752.1 - 1.6e-09 37.8 21.4 7.7 7.4 0.2 10.8 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAX21752.1 - 0.00015 21.1 5.5 0.067 12.4 0.0 4.9 3 1 2 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAX21752.1 - 0.00041 20.6 0.6 1.2 9.5 0.2 4.9 3 2 4 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX21752.1 - 0.00046 20.0 18.6 0.2 11.6 0.1 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAX21752.1 - 0.0011 19.4 6.2 6.1 7.8 0.2 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 GAX21752.1 - 0.0012 18.8 9.9 0.11 12.6 0.8 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.10 GAX21752.1 - 0.003 16.6 0.3 0.21 10.5 0.0 3.1 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 GAX21752.1 - 0.013 15.1 0.2 0.67 9.6 0.0 3.1 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) SRP_TPR_like PF17004.5 GAX21752.1 - 0.029 14.4 2.3 3.6 7.7 0.4 3.4 3 0 0 3 3 3 0 Putative TPR-like repeat Sel1 PF08238.12 GAX21752.1 - 0.14 12.9 6.8 55 4.6 0.8 4.5 4 0 0 4 4 4 0 Sel1 repeat Fis1_TPR_C PF14853.6 GAX21752.1 - 0.15 12.1 13.6 26 5.0 0.0 6.5 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 GAX21752.1 - 0.2 12.1 5.2 19 5.7 0.7 4.0 4 1 0 4 4 3 0 Bacterial transcriptional activator domain TPR_21 PF09976.9 GAX21752.1 - 0.41 10.3 7.1 0.41 10.3 0.2 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain PPR PF01535.20 GAX21752.1 - 1.7 9.1 3.2 50 4.5 0.1 3.9 5 0 0 5 5 2 0 PPR repeat SUIM_assoc PF16619.5 GAX21752.1 - 5.8 7.1 14.8 5.6 7.1 12.4 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HSF_DNA-bind PF00447.17 GAX21753.1 - 5.4e-20 71.8 0.0 8.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_S9 PF00380.19 GAX21754.1 - 7.5e-31 107.2 0.2 8.4e-31 107.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Metallophos PF00149.28 GAX21755.1 - 1.8e-31 110.3 0.1 2.8e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 GAX21755.1 - 2.5e-20 72.5 0.0 4.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 GAX21755.1 - 6.4e-15 54.3 5.7 0.00047 19.9 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21755.1 - 7.7e-13 47.5 11.4 0.00052 19.9 0.1 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX21755.1 - 6.3e-09 35.4 1.4 0.026 14.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX21755.1 - 8.3e-08 31.8 6.6 4.9e-05 22.9 0.4 3.2 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 GAX21755.1 - 2.4e-07 30.8 5.2 2.7e-05 24.2 0.9 3.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX21755.1 - 2.2e-06 28.2 6.6 0.0046 17.6 4.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX21755.1 - 7e-05 23.3 1.2 1.2 10.1 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX21755.1 - 0.00022 21.7 3.4 0.035 14.6 0.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX21755.1 - 0.00041 20.5 8.2 0.29 11.6 0.2 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX21755.1 - 0.0026 18.0 5.6 0.02 15.2 1.6 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX21755.1 - 0.046 13.8 0.8 2.7 8.2 0.2 2.6 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 GAX21755.1 - 0.11 11.8 1.3 0.27 10.6 0.1 2.0 2 1 0 2 2 2 0 MalT-like TPR region TPR_10 PF13374.6 GAX21755.1 - 1.4 8.9 3.3 42 4.2 1.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonuc_red_sm PF00268.21 GAX21756.1 - 5.2e-109 364.0 0.0 6.8e-109 363.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HAD PF12710.7 GAX21756.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA-synt_1c PF00749.21 GAX21758.1 - 3.4e-102 341.6 0.2 6e-102 340.7 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAX21758.1 - 2.1e-34 118.9 0.4 4.7e-34 117.8 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain WHEP-TRS PF00458.20 GAX21758.1 - 1.3e-07 31.7 0.6 1.3e-07 31.7 0.6 2.3 2 0 0 2 2 2 1 WHEP-TRS domain GST_C_3 PF14497.6 GAX21758.1 - 2e-06 27.9 0.1 0.0028 17.8 0.0 3.0 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX21758.1 - 1.6e-05 25.0 2.2 1.8e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 GAX21758.1 - 0.014 14.7 0.3 0.014 14.7 0.3 2.2 2 1 1 3 3 3 0 tRNA synthetases class I (C) catalytic domain Spt20 PF12090.8 GAX21758.1 - 0.072 12.7 8.5 2.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Spt20 family RIFIN PF02009.16 GAX21758.1 - 5.1 6.9 7.9 13 5.5 7.9 1.6 1 0 0 1 1 1 0 Rifin TPT PF03151.16 GAX21760.1 - 3e-29 102.3 13.4 6.4e-29 101.2 13.4 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF3245 PF11595.8 GAX21760.1 - 0.66 10.4 2.7 1.2 9.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Dimerisation2 PF16864.5 GAX21761.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain NOT2_3_5 PF04153.18 GAX21762.1 - 1.1e-22 80.5 3.4 1.1e-22 80.5 3.4 1.6 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Transglycosylas PF06737.14 GAX21762.1 - 0.12 13.1 2.8 0.31 11.7 2.8 1.7 1 0 0 1 1 1 0 Transglycosylase-like domain SHMT PF00464.19 GAX21763.1 - 4.8e-197 654.4 0.0 5.6e-197 654.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 GAX21763.1 - 0.18 11.1 0.0 0.45 9.8 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Synaptobrevin PF00957.21 GAX21764.1 - 8.3e-31 105.6 0.3 1.2e-30 105.2 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAX21764.1 - 2.9e-21 75.3 0.1 4.5e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.8 GAX21764.1 - 0.0066 17.5 0.1 0.029 15.4 0.0 1.9 2 0 0 2 2 2 1 SpoIIAA-like YxiJ PF14176.6 GAX21764.1 - 0.025 15.1 0.2 0.043 14.3 0.2 1.4 1 0 0 1 1 1 0 YxiJ-like protein Phage_Mu_Gam PF07352.12 GAX21764.1 - 0.053 13.4 0.6 0.073 13.0 0.6 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Rieske_2 PF13806.6 GAX21765.1 - 4e-21 74.9 0.0 5.3e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 GAX21765.1 - 6.6e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Methyltransf_11 PF08241.12 GAX21766.1 - 2.4e-11 44.1 0.3 5.5e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX21766.1 - 2.9e-08 34.3 0.1 6.3e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX21766.1 - 1.9e-06 28.5 0.3 5e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX21766.1 - 9.6e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAX21766.1 - 0.00099 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 GAX21766.1 - 0.0034 17.2 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX21766.1 - 0.0051 16.4 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 GAX21766.1 - 0.006 15.8 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 GAX21766.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAX21766.1 - 0.018 16.1 0.1 0.34 11.9 0.0 2.4 1 1 1 2 2 2 0 Zinc-binding dehydrogenase YueH PF14166.6 GAX21767.1 - 0.025 14.5 1.1 0.056 13.3 1.1 1.6 1 0 0 1 1 1 0 YueH-like protein LRR_4 PF12799.7 GAX21768.1 - 3.6e-10 39.9 2.4 0.31 11.5 0.1 5.3 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX21768.1 - 5.9e-07 29.2 0.6 0.12 12.2 0.1 4.3 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 GAX21768.1 - 3.8e-05 23.7 7.6 57 4.8 0.0 6.9 6 1 0 6 6 6 1 Leucine Rich Repeat 2OG-FeII_Oxy_3 PF13640.6 GAX21769.1 - 2.5e-13 50.7 0.0 5.3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PTPLA PF04387.14 GAX21769.1 - 2.3e-12 47.0 3.4 8.5e-10 38.6 1.0 2.4 1 1 1 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA 2OG-FeII_Oxy_4 PF13661.6 GAX21769.1 - 1.6e-09 38.3 0.0 4.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FeS PF04060.13 GAX21769.1 - 0.062 13.0 0.4 0.16 11.7 0.4 1.7 1 0 0 1 1 1 0 Putative Fe-S cluster RNA_pol_L_2 PF13656.6 GAX21770.1 - 1.8e-27 94.9 0.0 3.2e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAX21770.1 - 2.6e-07 30.0 0.0 4.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MbeD_MobD PF04899.12 GAX21770.1 - 0.033 14.3 0.2 0.053 13.6 0.2 1.3 1 0 0 1 1 1 0 MbeD/MobD like NinB PF05772.12 GAX21770.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 NinB protein RINGv PF12906.7 GAX21771.1 - 1.4e-13 50.7 5.6 2.8e-13 49.8 5.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 GAX21771.1 - 0.23 11.8 5.9 0.41 11.0 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain FAM176 PF14851.6 GAX21771.1 - 7.6 6.2 6.3 8 6.1 3.4 2.1 2 0 0 2 2 2 0 FAM176 family TCR PF03638.15 GAX21773.1 - 3e-22 78.6 53.9 3.7e-11 43.1 20.3 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain 2OG-FeII_Oxy_3 PF13640.6 GAX21775.1 - 3.4e-10 40.7 0.0 6.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CesT PF05932.13 GAX21775.1 - 0.042 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family Med3 PF11593.8 GAX21776.1 - 0.025 13.8 3.4 0.034 13.3 3.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pox_Ag35 PF03286.14 GAX21776.1 - 0.057 13.2 13.3 0.096 12.5 13.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 GAX21776.1 - 0.15 10.8 9.2 0.16 10.7 9.2 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 GAX21776.1 - 0.41 10.2 17.8 1.5 8.3 18.6 1.5 2 0 0 2 2 2 0 Spt20 family BSP_II PF05432.11 GAX21776.1 - 4.5 6.9 22.2 8.2 6.0 22.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM60A PF15396.6 GAX21776.1 - 8.2 6.4 9.8 13 5.8 9.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Arrestin_N PF00339.29 GAX21778.1 - 4.4e-06 26.8 0.0 0.00066 19.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MmgE_PrpD PF03972.14 GAX21778.1 - 0.05 12.1 0.1 0.069 11.7 0.1 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Mannitol_dh_C PF08125.13 GAX21780.1 - 0.011 15.3 0.4 0.61 9.5 0.4 2.3 1 1 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain NAD_binding_10 PF13460.6 GAX21782.1 - 1.5e-24 86.9 0.0 1.2e-23 83.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX21782.1 - 1.1e-11 44.7 0.0 1.9e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAX21782.1 - 0.00022 20.8 0.0 0.00053 19.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAX21782.1 - 0.0023 17.9 0.7 0.0044 17.0 0.0 1.8 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 GAX21782.1 - 0.0024 17.0 0.0 0.013 14.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAX21782.1 - 0.024 14.1 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 GAX21782.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus COX6B PF02297.17 GAX21783.1 - 5.6e-09 36.1 2.3 9.8e-09 35.3 2.3 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UQ_con PF00179.26 GAX21784.1 - 1.7e-26 92.5 0.0 2.5e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX21784.1 - 5.1e-07 29.5 0.0 8.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Prok-E2_A PF14457.6 GAX21784.1 - 0.024 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A RWD PF05773.22 GAX21784.1 - 0.11 12.8 3.4 0.26 11.6 3.4 1.6 1 1 0 1 1 1 0 RWD domain TPR_12 PF13424.6 GAX21785.1 - 1.1e-10 41.7 6.6 1.2e-07 31.9 1.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX21785.1 - 0.00055 19.8 1.6 0.89 9.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX21785.1 - 0.0022 17.8 2.0 1.3 8.9 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 GAX21785.1 - 0.013 15.0 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 GAX21785.1 - 0.02 14.9 3.6 0.36 11.0 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX21785.1 - 0.098 12.6 1.4 25 4.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 GAX21786.1 - 1.3e-46 158.8 0.0 1.5e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX21786.1 - 7.4e-11 43.1 0.0 8.9e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX21786.1 - 2.2e-09 37.3 0.1 6.7e-07 29.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 GAX21786.1 - 1.2e-06 28.2 0.0 0.0012 18.4 0.0 2.4 1 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 GAX21786.1 - 4.3e-06 26.7 0.1 1.6e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 GAX21786.1 - 0.0012 18.5 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 GAX21786.1 - 0.017 14.8 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 GAX21786.1 - 0.022 14.5 0.2 0.049 13.4 0.1 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 GAX21786.1 - 0.033 14.1 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 GAX21786.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Cu_amine_oxidN1 PF07833.11 GAX21787.1 - 0.073 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain FBPase PF00316.20 GAX21788.1 - 1.1e-32 113.0 0.0 2.7e-32 111.8 0.0 1.6 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain RSN1_7TM PF02714.15 GAX21789.1 - 7.7e-34 117.3 10.6 7.7e-34 117.3 10.6 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX21789.1 - 3e-31 108.3 2.2 3e-31 108.3 2.2 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX21789.1 - 4.8e-16 59.5 0.0 8.9e-11 42.3 0.0 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter TetR_C_35 PF18556.1 GAX21789.1 - 0.072 13.2 0.1 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain RSN1_TM PF13967.6 GAX21790.1 - 2.3e-33 115.2 1.7 2.3e-33 115.2 1.7 1.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX21790.1 - 2.2e-20 73.6 0.0 7.4e-14 52.4 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 GAX21790.1 - 1.3e-17 64.0 2.3 1.3e-17 64.0 2.3 1.8 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PsbU PF06514.11 GAX21791.1 - 7.7e-33 112.4 0.2 1e-32 112.0 0.2 1.2 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 GAX21791.1 - 3.3e-05 24.0 0.0 6.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Aconitase_2_N PF06434.13 GAX21792.1 - 4.2e-91 304.1 0.0 6.9e-91 303.4 0.0 1.4 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 GAX21792.1 - 5.1e-57 192.3 0.5 9.4e-57 191.4 0.5 1.5 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 GAX21792.1 - 3.9e-42 144.8 0.0 2.9e-40 138.7 0.0 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Glyco_transf_90 PF05686.12 GAX21793.1 - 1.6e-14 53.6 0.8 2.3e-14 53.1 0.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAX21793.1 - 0.019 15.3 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 RSN1_7TM PF02714.15 GAX21794.1 - 7.2e-46 156.7 19.1 7.2e-46 156.7 19.1 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX21794.1 - 1.1e-34 119.4 1.5 1.1e-34 119.4 1.5 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX21794.1 - 6.3e-17 62.4 0.0 2.8e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 GAX21795.1 - 5.5e-47 160.4 18.3 5.5e-47 160.4 18.3 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX21795.1 - 7.4e-32 110.3 1.4 7.4e-32 110.3 1.4 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX21795.1 - 4.3e-19 69.4 1.4 3.3e-11 43.7 0.2 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter ProRS-C_1 PF09180.11 GAX21795.1 - 0.094 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal DUF563 PF04577.14 GAX21796.1 - 2.5e-16 60.5 0.0 3.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF5098 PF17023.5 GAX21796.1 - 1.8 7.4 6.6 1.2 8.1 2.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5098) DUF563 PF04577.14 GAX21797.1 - 7.1e-16 59.0 0.0 1.3e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PT PF04886.12 GAX21799.1 - 0.014 14.9 12.4 0.014 14.9 12.4 3.4 3 0 0 3 3 3 0 PT repeat DUF2561 PF10812.8 GAX21799.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Pterin_bind PF00809.22 GAX21802.1 - 1.2e-76 257.7 0.0 1.5e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 GAX21802.1 - 2e-36 124.9 0.0 4.3e-35 120.6 0.0 2.4 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ACOX PF01756.19 GAX21803.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA oxidase PDZ PF00595.24 GAX21804.1 - 0.0089 16.4 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Apyrase PF06079.11 GAX21805.1 - 1.3e-97 326.5 0.1 1.6e-97 326.2 0.1 1.1 1 0 0 1 1 1 1 Apyrase Abhydrolase_2 PF02230.16 GAX21806.1 - 1.1e-51 175.7 0.0 1.5e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAX21806.1 - 5.5e-09 35.6 2.1 0.054 12.8 0.0 3.3 2 1 1 3 3 3 3 Serine aminopeptidase, S33 FSH1 PF03959.13 GAX21806.1 - 4.9e-08 32.9 0.0 2e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 GAX21806.1 - 3.4e-06 26.8 0.0 1.1e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX21806.1 - 4.8e-06 26.2 0.5 0.00016 21.3 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAX21806.1 - 0.00012 22.8 0.0 0.00015 22.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 GAX21806.1 - 0.00034 20.2 0.0 0.0008 19.0 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.7 GAX21806.1 - 0.00058 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX21806.1 - 0.0006 19.5 0.4 0.098 12.3 0.2 3.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 GAX21806.1 - 0.00087 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 GAX21806.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 GAX21806.1 - 0.037 14.0 0.4 2.1 8.2 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 GAX21806.1 - 0.041 13.2 0.3 0.093 12.0 0.3 1.7 1 1 0 1 1 1 0 Secretory lipase pPIWI_RE_REase PF18154.1 GAX21806.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 REase associating with pPIWI_RE Pkinase PF00069.25 GAX21807.1 - 5.5e-24 85.0 0.0 6.6e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21807.1 - 2.2e-14 53.4 0.0 2.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX21807.1 - 8.1e-06 24.9 0.0 1.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX21807.1 - 1.9e-05 24.7 0.1 0.0017 18.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAX21807.1 - 0.025 14.2 0.0 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 GAX21807.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_1 PF00561.20 GAX21808.1 - 3.2e-27 95.8 0.0 1.2e-25 90.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX21808.1 - 1.7e-19 71.3 1.9 2.6e-19 70.7 1.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX21808.1 - 8.4e-12 44.9 0.3 4.3e-11 42.5 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAX21808.1 - 4.5e-08 33.1 0.0 3.6e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 GAX21808.1 - 4.3e-05 23.7 0.0 6.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 GAX21808.1 - 0.00012 21.8 0.0 0.00031 20.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase DUF676 PF05057.14 GAX21808.1 - 0.0002 20.9 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 GAX21808.1 - 0.0004 20.2 0.0 0.0018 18.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 GAX21808.1 - 0.0007 18.4 0.0 0.0017 17.2 0.0 1.6 2 0 0 2 2 2 1 Ndr family Lipase_3 PF01764.25 GAX21808.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 GAX21808.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 GAX21808.1 - 0.031 13.8 0.0 4 6.9 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family EHN PF06441.12 GAX21808.1 - 0.047 14.1 0.1 0.14 12.6 0.0 1.8 2 0 0 2 2 1 0 Epoxide hydrolase N terminus Chlorophyllase2 PF12740.7 GAX21808.1 - 0.047 12.6 0.0 0.072 12.0 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.11 GAX21808.1 - 0.053 12.8 0.0 0.89 8.8 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydro_lipase PF04083.16 GAX21808.1 - 0.058 13.0 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 1 0 Partial alpha/beta-hydrolase lipase region Palm_thioest PF02089.15 GAX21808.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF2974 PF11187.8 GAX21808.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.11 GAX21808.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 1 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.16 GAX21808.1 - 0.12 12.1 0.0 2.8 7.7 0.0 2.9 4 0 0 4 4 4 0 Phospholipase/Carboxylesterase WbqC PF08889.11 GAX21811.1 - 0.0029 17.6 0.6 0.0048 16.8 0.6 1.2 1 0 0 1 1 1 1 WbqC-like protein family RHH_1 PF01402.21 GAX21811.1 - 0.086 12.8 0.3 0.45 10.5 0.3 2.2 1 1 0 1 1 1 0 Ribbon-helix-helix protein, copG family YL1 PF05764.13 GAX21811.1 - 3 7.9 13.9 0.28 11.3 0.5 2.6 2 0 0 2 2 2 0 YL1 nuclear protein zf-CDGSH PF09360.10 GAX21812.1 - 6.4e-09 35.9 0.2 1.1e-08 35.2 0.0 1.6 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type Acid_PPase PF12689.7 GAX21813.1 - 3.7e-25 88.7 0.0 7.6e-25 87.7 0.0 1.5 1 1 0 1 1 1 1 Acid Phosphatase Sec6 PF06046.13 GAX21814.1 - 8.6e-09 34.3 1.0 1.4e-08 33.6 0.7 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec6 ATP_bind_1 PF03029.17 GAX21814.1 - 0.1 12.4 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PhoU PF01895.19 GAX21814.1 - 0.64 10.5 3.8 3 8.4 0.7 3.0 2 0 0 2 2 2 0 PhoU domain ATP-synt_C PF00137.21 GAX21816.1 - 1.5e-34 118.1 37.3 5.5e-23 81.1 16.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ETF PF01012.21 GAX21817.1 - 1.2e-43 149.1 0.1 1.6e-43 148.7 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Exo_endo_phos PF03372.23 GAX21818.1 - 2e-08 34.0 0.0 1.5e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5122 PF17164.4 GAX21818.1 - 0.008 16.4 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5122) beta-propeller DUF4238 PF14022.6 GAX21818.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) Adaptin_N PF01602.20 GAX21819.1 - 1.5e-71 241.6 0.3 2.4e-66 224.4 0.2 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GAX21819.1 - 5.4e-19 68.8 0.2 2.4e-18 66.7 0.1 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAX21819.1 - 2.3e-06 27.9 2.4 0.00012 22.4 0.3 3.6 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 GAX21819.1 - 3.3e-05 23.8 14.6 0.007 16.5 0.1 6.7 7 0 0 7 7 7 2 HEAT repeat AP3B1_C PF14796.6 GAX21819.1 - 0.0002 21.7 0.2 0.00083 19.6 0.0 2.2 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_EZ PF13513.6 GAX21819.1 - 0.0017 18.8 2.9 0.0037 17.7 0.1 3.2 3 0 0 3 3 3 1 HEAT-like repeat Apt1 PF10351.9 GAX21819.1 - 0.74 8.6 17.0 1.2 7.9 17.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_L34 PF00468.17 GAX21820.1 - 3.4e-14 52.5 10.4 5e-14 52.0 10.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 GP120 PF00516.18 GAX21821.1 - 0.022 13.4 0.1 0.045 12.4 0.1 1.4 1 1 0 1 1 1 0 Envelope glycoprotein GP120 Enterotoxin_ST PF02048.16 GAX21821.1 - 0.14 12.6 1.5 31 5.1 0.0 3.3 3 0 0 3 3 3 0 Heat-stable enterotoxin ST DnaJ PF00226.31 GAX21822.1 - 0.011 15.8 3.0 0.029 14.5 0.2 2.6 2 0 0 2 2 2 0 DnaJ domain DUF1682 PF07946.14 GAX21822.1 - 0.013 14.8 3.8 0.025 13.8 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3584 PF12128.8 GAX21822.1 - 0.019 12.5 3.4 0.027 12.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_32 PF13654.6 GAX21822.1 - 0.019 13.8 2.3 0.029 13.2 2.3 1.2 1 0 0 1 1 1 0 AAA domain DUF2497 PF10691.9 GAX21822.1 - 0.043 14.2 1.6 0.21 12.0 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) DUF3450 PF11932.8 GAX21822.1 - 1.6 8.0 7.4 0.54 9.5 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) MCU PF04678.13 GAX21822.1 - 7.2 6.7 6.1 7.5 6.6 4.7 1.7 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Hid1 PF12722.7 GAX21822.1 - 8.2 4.4 6.3 12 3.9 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Enterotoxin_ST PF02048.16 GAX21823.1 - 0.6 10.6 3.3 37 4.9 0.0 3.2 3 0 0 3 3 3 0 Heat-stable enterotoxin ST HhH-GPD PF00730.25 GAX21825.1 - 2.7e-07 31.0 0.0 5.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UL20 PF17582.2 GAX21825.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20 UBA_4 PF14555.6 GAX21826.1 - 1.7e-14 53.3 0.0 3.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 GAX21826.1 - 5.7e-14 52.1 0.0 1.3e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 GAX21826.1 - 7.6e-11 42.1 0.0 6.7e-10 39.0 0.0 2.5 3 1 1 4 4 4 1 UBX domain UIM PF02809.20 GAX21826.1 - 0.0035 17.1 3.2 0.0035 17.1 3.2 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif RAP80_UIM PF18282.1 GAX21826.1 - 0.018 14.8 1.7 0.026 14.3 0.1 2.2 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif RXT2_N PF08595.11 GAX21826.1 - 0.78 9.8 5.1 1.3 9.0 1.9 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4611 PF15387.6 GAX21826.1 - 2.9 8.2 10.4 6 7.2 5.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 GAX21826.1 - 8.6 6.8 14.6 10 6.6 7.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal E1_dh PF00676.20 GAX21827.1 - 1.5e-88 296.7 0.0 1.7e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GAX21827.1 - 3.6e-08 33.3 0.5 4.5e-07 29.8 0.1 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 GAX21827.1 - 0.0016 17.7 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DUF2229 PF09989.9 GAX21828.1 - 0.026 14.2 0.1 0.034 13.8 0.1 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2383 PF09537.10 GAX21828.1 - 0.034 14.5 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) zf-FCS PF06467.14 GAX21828.1 - 0.045 13.7 0.1 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HisKA_3 PF07730.13 GAX21828.1 - 0.059 13.9 0.2 0.098 13.2 0.2 1.4 1 0 0 1 1 1 0 Histidine kinase Zn-ribbon_8 PF09723.10 GAX21828.1 - 0.06 13.5 1.0 0.14 12.3 1.0 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Chloroa_b-bind PF00504.21 GAX21829.1 - 5.2e-33 114.8 0.4 7.3e-33 114.4 0.4 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX21830.1 - 7.2e-30 104.6 0.0 9.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4334 PF14232.6 GAX21830.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) BtpA PF03437.15 GAX21830.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 BtpA family RNA_pol_Rpb2_6 PF00562.28 GAX21831.1 - 6.9e-112 374.4 0.0 1.7e-111 373.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAX21831.1 - 1.2e-28 100.1 0.0 1.8e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 GAX21831.1 - 1.5e-27 95.5 0.0 3.6e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 GAX21831.1 - 1.6e-16 60.1 0.0 4.5e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 GAX21831.1 - 4.8e-15 55.7 0.1 3.3e-14 53.1 0.1 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GAX21831.1 - 1.4e-11 44.4 0.0 1.1e-10 41.4 0.0 2.5 3 1 0 3 3 3 1 RNA polymerase Rpb2, domain 2 zf-C3HC4_3 PF13920.6 GAX21832.1 - 1e-07 31.6 8.1 1.9e-07 30.8 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX21832.1 - 0.00011 22.1 9.8 0.00022 21.1 9.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAX21832.1 - 0.00043 20.0 2.1 0.0012 18.6 2.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAX21832.1 - 0.0011 18.9 7.9 0.0035 17.3 7.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX21832.1 - 0.0014 18.9 8.8 0.0034 17.7 8.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAX21832.1 - 0.023 14.5 8.7 0.054 13.4 8.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAX21832.1 - 0.073 13.2 6.1 0.47 10.7 6.1 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAX21832.1 - 0.66 9.9 8.9 1.5 8.7 8.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_ab PF00006.25 GAX21834.1 - 4.4e-68 229.1 0.0 6.4e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAX21834.1 - 3.8e-12 46.5 0.4 7.3e-12 45.6 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_tranf_2_4 PF13704.6 GAX21836.1 - 1.1e-06 29.1 1.8 2.7e-06 27.8 1.8 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX21836.1 - 0.00061 19.5 0.3 0.00096 18.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 MARVEL PF01284.23 GAX21838.1 - 0.00099 19.2 17.6 0.026 14.6 3.0 3.3 1 1 3 4 4 4 2 Membrane-associating domain Ribosomal_L27e PF01777.18 GAX21840.1 - 3.3e-26 91.5 12.6 4.9e-26 90.9 12.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 GAX21840.1 - 2.7e-05 24.0 0.8 2.7e-05 24.0 0.8 2.5 2 1 0 2 2 2 1 KOW motif MAP65_ASE1 PF03999.12 GAX21841.1 - 3e-61 207.9 33.6 3.5e-60 204.4 34.0 1.9 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) DUF1818 PF08848.11 GAX21841.1 - 0.034 14.2 5.6 0.13 12.3 3.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) ApoLp-III PF07464.11 GAX21841.1 - 0.052 13.6 5.7 1.4 9.0 0.8 3.4 3 1 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) zf-met2 PF12907.7 GAX21842.1 - 1.2e-12 47.7 0.3 2e-12 47.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding zf-C2H2_4 PF13894.6 GAX21842.1 - 0.15 13.0 0.1 0.26 12.2 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger HAD_2 PF13419.6 GAX21843.1 - 1e-24 87.6 0.0 5.1e-24 85.3 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX21843.1 - 1.2e-10 41.2 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX21843.1 - 5.9e-10 39.8 0.0 1.8e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX21843.1 - 0.00014 22.3 0.0 0.00027 21.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FKS1_dom1 PF14288.6 GAX21844.1 - 2.2e-20 73.3 3.9 1.2e-19 71.0 3.9 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glucan_synthase PF02364.15 GAX21844.1 - 1.8e-13 49.6 0.0 3.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Glucan_synthase PF02364.15 GAX21845.1 - 2.4e-33 115.4 4.6 2.4e-33 115.4 4.6 1.5 1 1 0 2 2 2 1 1,3-beta-glucan synthase component Vma12 PF11712.8 GAX21845.1 - 0.19 11.8 2.2 2.2 8.4 0.2 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DHHC PF01529.20 GAX21846.1 - 1.9e-36 125.1 11.1 3.7e-36 124.2 11.1 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Sec15 PF04091.12 GAX21847.1 - 4.4e-15 55.9 0.0 1.9e-14 53.8 0.0 2.0 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Ribosomal_L37 PF08561.10 GAX21848.1 - 1.4e-09 38.5 5.1 2.8e-07 31.1 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 PNRC PF15365.6 GAX21849.1 - 1.4e-06 27.9 3.3 1.4e-06 27.9 3.3 4.1 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif DUF648 PF04890.13 GAX21849.1 - 0.13 12.0 3.4 0.16 11.7 3.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DGF-1_C PF11040.8 GAX21849.1 - 1.8 8.6 5.0 3.7 7.6 0.8 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Macoilin PF09726.9 GAX21849.1 - 1.9 6.9 19.8 2.4 6.6 19.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF1387 PF07139.11 GAX21849.1 - 2.4 7.8 20.4 3.2 7.4 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) MIP PF00230.20 GAX21850.1 - 6e-17 62.1 8.5 6.8e-16 58.7 4.0 2.1 1 1 1 2 2 2 2 Major intrinsic protein DUF4148 PF13663.6 GAX21851.1 - 0.1 12.8 1.1 0.35 11.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Peptidase_M50 PF02163.22 GAX21853.1 - 1e-53 182.2 0.1 1.5e-53 181.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 GAX21853.1 - 2.6e-05 24.5 0.0 6.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX21853.1 - 7.8e-05 22.4 0.3 0.00021 21.1 0.3 1.8 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX21853.1 - 0.00023 21.5 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 GAX21853.1 - 0.13 12.2 0.1 1.1 9.2 0.0 2.5 1 1 1 2 2 2 0 Tricorn protease PDZ domain YjgF_endoribonc PF14588.6 GAX21854.1 - 8.4e-22 77.9 0.0 9.5e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 GAX21854.1 - 1.5e-15 57.3 0.0 2.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP HpaB_N PF11794.8 GAX21854.1 - 0.076 12.7 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal HECT PF00632.25 GAX21855.1 - 2.5e-81 273.5 0.0 3.3e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) 2OG-FeII_Oxy_3 PF13640.6 GAX21856.1 - 1.6e-15 57.8 0.1 1.6e-15 57.8 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX21856.1 - 8.1e-05 23.0 0.0 0.00026 21.4 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1599 PF07659.11 GAX21856.1 - 0.092 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 MBD PF01429.19 GAX21857.1 - 9.2e-08 31.7 0.0 2.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain EMP70 PF02990.16 GAX21858.1 - 9.8e-191 634.9 7.6 1.4e-190 634.4 7.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF1043 PF06295.12 GAX21858.1 - 0.035 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) zf-MYND PF01753.18 GAX21860.1 - 7.2e-13 48.4 34.7 7.9e-09 35.5 16.6 2.9 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 GAX21860.1 - 6.3 7.0 22.1 0.21 11.7 1.5 3.2 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_pol_phi PF04931.13 GAX21861.1 - 0.096 10.8 10.7 0.17 10.0 10.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi Cytomega_UL84 PF06284.11 GAX21861.1 - 0.4 9.1 6.2 0.63 8.4 6.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Pox_Ag35 PF03286.14 GAX21861.1 - 1.3 8.8 10.6 0.32 10.7 5.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1754 PF08555.10 GAX21861.1 - 2.9 8.8 9.7 2.6 8.9 4.6 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Nop14 PF04147.12 GAX21861.1 - 2.9 6.0 12.1 0.33 9.1 6.6 1.9 2 0 0 2 2 2 0 Nop14-like family FAM176 PF14851.6 GAX21861.1 - 3 7.5 9.7 1.5 8.5 5.2 2.2 2 0 0 2 2 2 0 FAM176 family DUF2284 PF10050.9 GAX21862.1 - 0.051 13.3 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) DDE_Tnp_4 PF13359.6 GAX21863.1 - 7.7e-13 48.4 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAX21863.1 - 0.00047 19.9 0.0 0.0009 18.9 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain DUF3493 PF11998.8 GAX21864.1 - 2.3e-21 75.8 0.3 4e-21 75.0 0.3 1.4 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 DnaB PF00772.21 GAX21864.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Phage_T7_Capsid PF05396.11 GAX21864.1 - 0.17 12.3 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 Phage T7 capsid assembly protein Abhydrolase_1 PF00561.20 GAX21865.1 - 0.00034 20.3 0.1 0.00085 19.0 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX21865.1 - 0.031 13.5 0.4 0.27 10.5 0.4 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S51 PF03575.17 GAX21866.1 - 2.4e-12 47.0 0.0 2.4e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S51 CbiA PF01656.23 GAX21867.1 - 0.18 11.8 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DNA_methylase PF00145.17 GAX21868.1 - 8.6e-08 31.9 0.4 0.00063 19.2 0.0 4.0 3 1 1 4 4 4 3 C-5 cytosine-specific DNA methylase zf-MYND PF01753.18 GAX21869.1 - 4.3e-09 36.3 13.0 4.3e-09 36.3 13.0 1.8 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 GAX21870.1 - 3.4e-07 30.2 16.9 7.5e-07 29.1 16.9 1.6 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 GAX21870.1 - 6.2 7.3 8.6 14 6.1 8.6 1.5 1 0 0 1 1 1 0 Rhodanase C-terminal HSP70 PF00012.20 GAX21871.1 - 4.8e-156 520.4 0.1 6.7e-97 325.1 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GAX21871.1 - 1.3e-09 37.4 0.2 7e-08 31.7 0.1 2.5 3 0 0 3 3 3 2 MreB/Mbl protein DDR PF08841.10 GAX21871.1 - 0.05 12.6 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain EF-hand_13 PF17958.1 GAX21872.1 - 3.6e-35 119.7 2.6 2.1e-34 117.2 0.2 3.4 5 0 0 5 5 5 1 EF-hand domain EF-hand_7 PF13499.6 GAX21872.1 - 4e-16 59.2 7.3 8.6e-14 51.7 0.9 3.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX21872.1 - 2.3e-06 26.7 0.9 0.018 14.6 0.0 4.9 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 GAX21872.1 - 1.6e-05 24.4 0.2 0.62 10.2 0.0 4.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 GAX21872.1 - 0.00035 19.9 3.0 0.0019 17.6 0.0 3.6 4 0 0 4 4 4 1 EF hand DUF4187 PF13821.6 GAX21872.1 - 0.031 14.1 0.3 0.073 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) EF-hand_8 PF13833.6 GAX21872.1 - 0.14 12.0 2.6 1.3 8.9 0.1 3.3 2 1 0 3 3 3 0 EF-hand domain pair RCC1_2 PF13540.6 GAX21874.1 - 1.6e-27 94.6 8.7 1.8e-06 27.5 0.1 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAX21874.1 - 5.7e-26 90.9 12.1 6.2e-10 39.6 0.2 6.4 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 GAX21874.1 - 0.0026 18.0 0.2 0.013 15.7 0.0 2.3 3 0 0 3 3 3 1 Putative heavy-metal chelation SNRNP27 PF08648.12 GAX21875.1 - 6.3e-26 90.2 3.0 1.7e-25 88.9 2.3 2.0 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Fer4 PF00037.27 GAX21876.1 - 1.8e-14 52.8 17.1 1.6e-08 34.0 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 GAX21876.1 - 4.7e-13 49.5 11.0 7.1e-13 48.9 11.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAX21876.1 - 4.9e-11 43.4 5.3 3.3e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 GAX21876.1 - 2.3e-09 37.2 21.2 4.9e-07 29.8 12.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 GAX21876.1 - 3.3e-09 36.7 31.9 1.6e-06 28.1 11.8 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAX21876.1 - 9e-09 35.4 10.7 1.4e-08 34.7 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAX21876.1 - 9.7e-09 35.6 3.4 0.00038 20.9 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAX21876.1 - 3e-07 30.1 12.7 0.0025 17.8 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 GAX21876.1 - 3.5e-07 30.0 18.0 0.00037 20.4 5.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 GAX21876.1 - 1.2e-05 25.4 11.7 0.00048 20.4 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GAX21876.1 - 0.00024 21.6 12.4 0.069 13.7 3.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 GAX21876.1 - 0.0094 16.2 5.5 0.84 9.9 0.4 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 GAX21876.1 - 0.025 15.1 15.2 0.65 10.6 2.7 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 GAX21876.1 - 0.044 13.9 4.6 0.25 11.5 0.3 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 GAX21876.1 - 0.1 12.8 8.5 2.4 8.4 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 GAX21876.1 - 0.11 13.5 17.2 0.32 12.0 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 GAX21876.1 - 0.73 10.7 11.3 2.6 9.0 1.8 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain TPT PF03151.16 GAX21877.1 - 2.6e-09 36.8 22.3 3e-09 36.6 22.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX21877.1 - 5.1e-07 29.9 26.7 7.6e-07 29.4 11.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family Op_neuropeptide PF08035.11 GAX21877.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.1 3 0 0 3 3 3 0 Opioids neuropeptide PSII_Pbs27 PF13326.6 GAX21878.1 - 6.3e-36 123.8 0.8 8e-36 123.5 0.1 1.4 2 0 0 2 2 2 1 Photosystem II Pbs27 Peptidase_M3 PF01432.20 GAX21879.1 - 2.3e-138 462.3 0.0 3.1e-138 461.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 GAX21879.1 - 0.015 14.9 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like PPR_long PF17177.4 GAX21880.1 - 1.8e-35 122.2 1.1 1.7e-27 96.2 0.1 2.1 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PRORP PF16953.5 GAX21880.1 - 2.4e-25 89.5 0.3 4e-25 88.7 0.3 1.3 1 0 0 1 1 1 1 Protein-only RNase P PPR_2 PF13041.6 GAX21880.1 - 1.1e-07 31.9 0.5 0.36 11.1 0.0 4.0 4 0 0 4 4 4 3 PPR repeat family RNase_Zc3h12a PF11977.8 GAX21880.1 - 5.3e-06 26.3 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_3 PF13812.6 GAX21880.1 - 8e-06 25.8 0.0 0.022 14.8 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 GAX21880.1 - 5.3e-05 23.2 0.0 2.8 8.4 0.0 4.5 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.7 GAX21880.1 - 0.0018 17.9 0.1 1.9 8.3 0.1 3.2 3 0 0 3 3 3 2 PPR repeat Homez PF11569.8 GAX21880.1 - 0.041 13.3 0.5 1.6 8.3 0.1 2.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez TPR_MalT PF17874.1 GAX21880.1 - 0.056 12.8 2.1 0.12 11.8 1.7 1.7 2 0 0 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 GAX21880.1 - 0.4 11.6 2.1 25 6.0 0.8 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Skp1 PF01466.19 GAX21881.1 - 2.6e-27 94.7 0.1 5e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAX21881.1 - 4.2e-18 65.3 0.3 8.5e-18 64.3 0.3 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 GAX21881.1 - 0.0023 18.1 1.4 0.021 15.0 0.2 2.1 1 1 1 2 2 2 1 BTB/POZ domain RMI1_C PF16099.5 GAX21881.1 - 0.032 14.1 0.3 0.07 13.0 0.2 1.6 1 1 1 2 2 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold DUF1450 PF07293.11 GAX21881.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) GRIP PF01465.20 GAX21883.1 - 1.7e-14 53.5 1.1 3e-14 52.6 0.2 2.0 2 0 0 2 2 2 1 GRIP domain SH3BGR PF04908.15 GAX21883.1 - 1.8e-05 24.8 0.3 0.00017 21.7 0.0 2.9 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein ADIP PF11559.8 GAX21883.1 - 0.00034 20.7 9.7 0.00034 20.7 9.7 7.6 2 1 6 8 8 8 3 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 GAX21883.1 - 0.00076 18.3 20.6 0.00076 18.3 20.6 3.5 1 1 2 3 3 3 2 AAA domain Imm42 PF15593.6 GAX21883.1 - 0.017 15.6 0.1 0.082 13.4 0.1 2.3 1 0 0 1 1 1 0 Immunity protein 42 HALZ PF02183.18 GAX21883.1 - 3.1 8.1 8.0 2.2 8.6 0.0 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF285 PF03382.14 GAX21884.1 - 1.7e-50 169.9 27.8 1.5e-24 86.0 10.2 3.3 2 1 1 3 3 3 3 Mycoplasma protein of unknown function, DUF285 6PF2K PF01591.18 GAX21885.1 - 1.7e-63 214.0 0.0 2.4e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAX21885.1 - 2.5e-29 102.4 0.0 1.7e-28 99.7 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAX21885.1 - 1.4e-10 41.5 0.0 3.9e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAX21885.1 - 0.029 14.8 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAX21885.1 - 0.066 12.9 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 GAX21885.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAX21885.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF285 PF03382.14 GAX21886.1 - 4.5e-49 165.2 16.9 4.9e-26 90.9 6.4 2.4 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 DUF3899 PF13038.6 GAX21886.1 - 0.12 12.9 0.0 1 9.9 0.0 2.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF285 PF03382.14 GAX21887.1 - 4.4e-50 168.5 28.3 1.5e-27 95.7 12.8 2.5 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 NUDIX PF00293.28 GAX21888.1 - 2.2e-16 60.1 0.0 2.5e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 GAX21888.1 - 0.0026 17.7 0.6 0.0074 16.3 0.6 1.7 1 1 0 1 1 1 1 NUDIX domain VP9 PF09625.10 GAX21890.1 - 0.14 12.3 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 VP9 protein EF-hand_7 PF13499.6 GAX21892.1 - 1.6e-12 47.7 2.3 9.6e-07 29.2 0.1 2.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAX21892.1 - 9.1e-12 43.6 0.4 6.8e-06 25.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX21892.1 - 5.2e-09 35.3 0.0 0.00028 20.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX21892.1 - 1.9e-08 33.4 0.1 0.0082 15.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 GAX21892.1 - 7.5e-05 22.6 1.8 0.16 11.9 0.0 2.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 GAX21892.1 - 0.0001 22.0 1.2 0.0025 17.6 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAX21892.1 - 0.12 12.8 0.0 0.38 11.1 0.0 1.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Tmemb_14 PF03647.13 GAX21894.1 - 2.5e-25 89.1 10.5 3e-25 88.8 10.5 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3918 PF13056.6 GAX21894.1 - 0.072 12.7 0.0 0.072 12.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) DUF2157 PF09925.9 GAX21894.1 - 0.085 12.6 1.2 0.12 12.1 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF5518 PF17647.1 GAX21894.1 - 0.94 9.6 11.9 12 6.1 11.8 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5518) PITH PF06201.13 GAX21895.1 - 1.3e-33 116.3 0.0 1.6e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain SQS_PSY PF00494.19 GAX21896.1 - 5.5e-24 85.1 0.6 7.2e-24 84.7 0.6 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Gasdermin_C PF17708.1 GAX21896.1 - 0.02 15.0 2.7 0.14 12.3 1.7 2.0 1 1 1 2 2 2 0 Gasdermin PUB domain LRR_8 PF13855.6 GAX21897.1 - 1.4e-17 63.2 32.8 7.9e-07 28.7 1.3 6.9 5 2 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 GAX21897.1 - 2.5e-09 37.3 34.0 0.00011 22.5 0.8 8.1 3 3 8 11 11 11 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAX21897.1 - 0.0018 18.2 14.4 0.31 11.2 0.6 8.1 8 0 0 8 8 8 1 Leucine Rich repeat LRR_1 PF00560.33 GAX21897.1 - 0.0027 18.0 29.8 4.1 8.3 0.1 11.1 12 2 0 12 12 12 3 Leucine Rich Repeat DUF3246 PF11596.8 GAX21899.1 - 0.003 17.0 4.1 0.0046 16.4 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Dicty_CAD PF05720.12 GAX21899.1 - 0.11 12.5 0.5 0.39 10.7 0.1 2.1 1 1 1 2 2 2 0 Cell-cell adhesion domain MRI PF15325.6 GAX21899.1 - 0.6 11.2 6.0 0.63 11.1 4.2 1.8 1 1 1 2 2 2 0 Modulator of retrovirus infection Pox_Ag35 PF03286.14 GAX21899.1 - 4.3 7.1 7.7 7.8 6.2 4.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein EphA2_TM PF14575.6 GAX21900.1 - 0.064 14.1 1.5 3.8 8.4 0.0 3.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Macoilin PF09726.9 GAX21900.1 - 0.16 10.5 3.8 0.2 10.2 3.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF4834 PF16118.5 GAX21900.1 - 9.4 7.3 0.0 9.4 7.3 0.0 3.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM100 PF16311.5 GAX21901.1 - 0.23 11.0 1.1 0.42 10.2 1.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 DUF4381 PF14316.6 GAX21902.1 - 0.0052 17.0 0.3 0.0094 16.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF3328 PF11807.8 GAX21902.1 - 0.048 13.4 0.3 0.12 12.2 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF2207 PF09972.9 GAX21902.1 - 0.17 10.6 0.2 0.23 10.2 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 GAX21903.1 - 0.047 13.8 0.5 0.095 12.8 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2561 PF10812.8 GAX21903.1 - 0.05 13.6 0.1 0.05 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF1467 PF07330.12 GAX21904.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) SWIRM-assoc_2 PF16496.5 GAX21904.1 - 1.6 7.5 9.5 3.3 6.5 9.5 1.5 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ank_2 PF12796.7 GAX21905.1 - 0.00049 20.6 0.1 0.04 14.5 0.1 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX21905.1 - 0.014 15.8 0.4 65 4.6 0.0 4.8 4 0 0 4 4 4 0 Ankyrin repeat Fer2_4 PF13510.6 GAX21905.1 - 0.18 11.8 0.2 0.35 11.0 0.2 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Methyltransf_21 PF05050.12 GAX21906.1 - 1.8e-08 34.6 0.1 2e-07 31.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase FkbM domain SAND PF01342.21 GAX21906.1 - 0.12 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 SAND domain BBL5 PF07289.11 GAX21908.1 - 0.015 14.3 0.7 0.019 14.0 0.0 1.4 2 0 0 2 2 2 0 Bardet-Biedl syndrome 5 protein Acetyltransf_3 PF13302.7 GAX21908.1 - 0.092 13.4 0.0 0.15 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PDDEXK_4 PF14281.6 GAX21909.1 - 0.0094 16.1 0.0 0.26 11.4 0.0 2.5 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Acetyltransf_1 PF00583.25 GAX21909.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TK PF00265.18 GAX21909.1 - 0.16 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Endonuclease_1 PF04231.13 GAX21910.1 - 1.8e-14 54.0 0.4 4.3e-14 52.8 0.1 1.8 2 0 0 2 2 2 1 Endonuclease I IMP2_C PF18591.1 GAX21911.1 - 0.096 12.6 0.0 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 Immune Mapped Protein 2 (IMP2) C-terminal domain DUF2786 PF10979.8 GAX21911.1 - 0.19 11.7 0.4 96 3.0 0.9 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2786) DUF5522 PF17653.1 GAX21912.1 - 3.1e-21 75.1 6.4 6.8e-21 74.0 6.4 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 GAX21912.1 - 2.2e-06 27.3 0.0 3.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Diphthamide synthase Peripla_BP_2 PF01497.18 GAX21912.1 - 0.00039 20.1 0.0 0.0064 16.1 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein Radical_SAM PF04055.21 GAX21912.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Radical SAM superfamily Oxidored-like PF09791.9 GAX21912.1 - 0.21 11.3 2.3 0.52 10.0 2.3 1.6 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal Abhydrolase_6 PF12697.7 GAX21913.1 - 8.5e-10 39.6 0.4 1.2e-09 39.1 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAX21913.1 - 2.9e-05 24.0 0.0 0.00054 19.9 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 GAX21913.1 - 3.9e-05 23.4 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 GAX21913.1 - 0.00013 21.5 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 GAX21913.1 - 0.00014 21.2 0.0 0.00044 19.6 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 GAX21913.1 - 0.0014 18.6 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GAX21913.1 - 0.0065 16.0 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 GAX21913.1 - 0.02 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain RE_HpaII PF09561.10 GAX21913.1 - 0.042 13.2 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 HpaII restriction endonuclease Esterase PF00756.20 GAX21913.1 - 0.046 13.4 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Say1_Mug180 PF10340.9 GAX21913.1 - 0.27 10.0 0.0 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF5325 PF17259.2 GAX21914.1 - 0.21 11.5 0.2 0.35 10.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5325) UPF0061 PF02696.14 GAX21915.1 - 2.3e-62 211.3 0.3 2.7e-32 112.2 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family APOC4 PF15119.6 GAX21915.1 - 0.053 13.8 0.3 6.3 7.1 0.1 2.6 2 0 0 2 2 2 0 Apolipoprotein C4 TMEM208_SND2 PF05620.11 GAX21917.1 - 1.4e-10 41.2 5.8 2.3e-10 40.5 5.8 1.3 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 HATPase_c PF02518.26 GAX21918.1 - 2.6e-24 85.9 0.0 1.3e-23 83.7 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX21918.1 - 1.9e-23 82.8 0.2 3.5e-23 81.9 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX21918.1 - 2.7e-10 40.2 0.0 1.1e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX21918.1 - 0.0021 17.9 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF308 PF03729.13 GAX21918.1 - 0.16 12.3 5.3 0.35 11.2 5.3 1.5 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) HATPase_c PF02518.26 GAX21919.1 - 4.1e-23 82.0 0.1 1.3e-22 80.4 0.0 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX21919.1 - 5e-23 81.4 0.3 9.8e-23 80.5 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX21919.1 - 2.3e-09 37.2 0.0 8.1e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX21919.1 - 0.0014 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF308 PF03729.13 GAX21919.1 - 0.094 13.1 2.7 0.21 11.9 2.7 1.5 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Pkinase PF00069.25 GAX21920.1 - 1.2e-37 129.8 0.1 2.9e-36 125.2 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX21920.1 - 9.4e-27 93.9 0.1 9.3e-26 90.7 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX21920.1 - 0.00062 19.2 0.0 0.00092 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX21920.1 - 0.0079 15.0 0.0 0.017 13.9 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX21920.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 GAX21920.1 - 0.072 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 GAX21920.1 - 0.099 12.2 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1798 PF08807.10 GAX21920.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF3134 PF11332.8 GAX21920.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Glyco_tranf_2_3 PF13641.6 GAX21921.1 - 3.6e-15 56.5 0.0 7.5e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX21921.1 - 1e-11 44.9 0.0 3.7e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Peptidase_M43 PF05572.13 GAX21922.1 - 4.7e-16 59.1 0.0 8.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX21922.1 - 0.00017 21.8 2.2 0.00027 21.2 0.0 2.4 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX21922.1 - 0.0039 16.9 0.9 0.0095 15.6 0.0 2.0 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX21922.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAX21922.1 - 0.06 12.3 0.4 0.11 11.4 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 GAX21922.1 - 0.085 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 GAX21922.1 - 0.097 12.6 1.3 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 GAX21922.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Met-zincin DnaJ PF00226.31 GAX21924.1 - 1e-18 67.2 0.9 1.8e-18 66.4 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 GAX21924.1 - 3.8e-05 23.5 6.0 3.8e-05 23.5 6.0 3.1 2 2 1 3 3 3 2 Transmembrane Fragile-X-F protein TetR_C_35 PF18556.1 GAX21928.1 - 0.028 14.6 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain Biotin_lipoyl PF00364.22 GAX21930.1 - 1.2e-16 60.3 3.7 1.7e-16 59.8 3.7 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 GAX21930.1 - 0.0048 17.6 4.2 0.26 12.0 1.1 2.3 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 GAX21930.1 - 0.0076 16.1 1.4 0.013 15.4 1.2 1.5 1 1 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 GAX21930.1 - 0.021 14.1 1.9 0.69 9.1 0.2 2.1 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 GAX21930.1 - 0.029 14.2 3.5 1.1 9.1 0.6 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like DUF1179 PF06678.11 GAX21930.1 - 0.87 9.6 5.1 0.27 11.3 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) WD40 PF00400.32 GAX21931.1 - 6.1e-27 93.3 17.1 2.2e-06 28.3 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Bromodomain PF00439.25 GAX21931.1 - 1.5e-24 85.9 1.0 2.2e-12 46.9 0.0 2.6 2 0 0 2 2 2 2 Bromodomain Ge1_WD40 PF16529.5 GAX21931.1 - 0.088 11.8 0.0 13 4.6 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_21 PF13304.6 GAX21931.1 - 2.7 7.7 9.7 0.031 14.1 0.5 2.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system HATPase_c PF02518.26 GAX21932.1 - 1.1e-27 96.8 0.0 1.9e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX21932.1 - 1.2e-22 80.2 0.1 2e-21 76.2 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAX21932.1 - 3.2e-21 75.1 0.1 6.7e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 GAX21932.1 - 0.13 12.3 0.1 5.7 7.0 0.0 2.5 2 0 0 2 2 2 0 PAS fold TPX2_importin PF12214.8 GAX21933.1 - 1.7e-13 51.1 4.4 3.5e-07 30.6 0.2 2.9 3 0 0 3 3 3 2 Cell cycle regulated microtubule associated protein MFS_1 PF07690.16 GAX21934.1 - 8.2e-22 77.6 24.8 8.2e-22 77.6 24.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Haemadin PF09065.10 GAX21934.1 - 0.12 12.2 0.6 0.24 11.2 0.6 1.5 1 0 0 1 1 1 0 Haemadin DUF1146 PF06612.11 GAX21934.1 - 4.2 7.5 9.9 5.1 7.2 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) MFS_1 PF07690.16 GAX21935.1 - 1.2e-16 60.7 11.3 1.2e-16 60.7 11.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1538 PF07556.11 GAX21935.1 - 0.0033 16.7 3.5 0.0033 16.7 3.5 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1538) LapA_dom PF06305.11 GAX21935.1 - 0.5 10.2 9.2 0.17 11.8 0.6 3.4 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain HSF_DNA-bind PF00447.17 GAX21936.1 - 2.2e-17 63.5 0.6 3.5e-17 62.8 0.6 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 GAX21936.1 - 0.0028 18.1 0.1 0.0051 17.2 0.1 1.4 1 0 0 1 1 1 1 Ets-domain ABC1 PF03109.16 GAX21937.1 - 1.6e-30 105.7 0.0 3.4e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GAX21937.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain SIS PF01380.22 GAX21939.1 - 6.6e-22 77.8 0.5 9.8e-08 31.9 0.2 3.8 3 1 0 3 3 3 3 SIS domain GATase_6 PF13522.6 GAX21939.1 - 6.9e-18 65.1 0.1 1.7e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX21939.1 - 3.4e-11 43.1 0.1 1.1e-10 41.5 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAX21939.1 - 0.017 14.0 0.1 0.03 13.2 0.1 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DSPc PF00782.20 GAX21939.1 - 0.096 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain bact-PGI_C PF10432.9 GAX21939.1 - 0.13 12.3 0.1 1.8 8.6 0.0 2.9 2 1 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain Glyco_transf_8C PF08437.10 GAX21939.1 - 0.2 11.7 1.0 0.38 10.9 0.2 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal BTD PF09270.10 GAX21940.1 - 0.066 13.4 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain wnt PF00110.19 GAX21940.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 wnt family IQ PF00612.27 GAX21944.1 - 3.1e-86 275.1 265.5 0.00054 19.5 0.4 41.7 40 2 2 42 42 42 38 IQ calmodulin-binding motif UDPG_MGDP_dh_C PF03720.15 GAX21944.1 - 0.11 12.9 1.7 4.5 7.7 0.3 4.0 3 1 1 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ANAPC4 PF12896.7 GAX21945.1 - 1.6e-14 53.9 1.8 2.8e-14 53.1 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 GAX21945.1 - 4.4e-07 30.1 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain RVT_2 PF07727.14 GAX21949.1 - 3.2e-33 115.4 0.0 6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GAX21950.1 - 9.2e-11 41.8 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SAICAR_synt PF01259.18 GAX21951.1 - 1.7e-75 253.9 0.0 2.2e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase DUF3592 PF12158.8 GAX21952.1 - 0.078 13.0 0.2 0.099 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) DUF883 PF05957.13 GAX21952.1 - 3.8 8.2 6.9 24 5.6 6.9 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) NAD_synthase PF02540.17 GAX21953.1 - 0.00027 20.1 0.1 0.00068 18.8 0.1 1.6 1 1 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 GAX21953.1 - 0.00078 18.3 0.0 0.0066 15.3 0.0 2.2 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 GAX21953.1 - 0.0053 16.5 0.2 0.013 15.2 0.1 1.7 1 1 0 1 1 1 1 Asparagine synthase QueC PF06508.13 GAX21953.1 - 0.024 14.1 1.6 4.9 6.6 0.0 2.7 2 1 0 3 3 3 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 GAX21953.1 - 0.99 9.1 5.1 0.47 10.2 0.2 3.0 2 1 1 3 3 3 0 PP-loop family Polysacc_deac_1 PF01522.21 GAX21954.1 - 1.2e-10 41.3 0.2 0.001 19.0 0.0 3.2 3 1 0 3 3 3 2 Polysaccharide deacetylase CXCXC PF03128.14 GAX21954.1 - 0.0076 16.6 14.3 0.038 14.4 3.0 3.2 2 0 0 2 2 2 2 CXCXC repeat DUF2922 PF11148.8 GAX21954.1 - 0.14 11.9 0.0 19 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) DUF2517 PF10725.9 GAX21954.1 - 0.14 11.9 0.3 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) SNF2_N PF00176.23 GAX21955.1 - 8.2e-60 202.4 0.0 2.2e-59 200.9 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX21955.1 - 1.1e-17 64.4 0.0 2.7e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 GAX21955.1 - 7.3e-12 45.0 2.6 9.7e-05 22.2 0.2 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 GAX21955.1 - 6.9e-08 32.7 0.0 4e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX21955.1 - 1.2e-05 25.2 1.0 0.0002 21.2 0.0 3.3 3 1 0 3 3 3 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAX21955.1 - 0.00015 21.0 0.0 0.00043 19.5 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 GAX21955.1 - 0.004 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF218 PF02698.17 GAX21957.1 - 0.0072 16.4 0.8 4.9 7.2 0.0 3.1 3 0 0 3 3 3 2 DUF218 domain ING PF12998.7 GAX21957.1 - 0.06 13.9 0.2 0.06 13.9 0.2 3.0 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding TMF_TATA_bd PF12325.8 GAX21957.1 - 0.37 11.0 19.5 0.0075 16.5 7.9 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Med10 PF09748.9 GAX21957.1 - 0.63 10.0 2.8 2.3 8.2 2.8 2.0 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex TPT PF03151.16 GAX21958.1 - 2.4e-14 53.4 4.6 3.1e-14 53.0 4.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX21958.1 - 4.1e-12 46.4 21.2 2.5e-10 40.7 8.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAX21958.1 - 7.2e-08 32.0 7.6 1.2e-07 31.3 7.6 1.3 1 1 0 1 1 1 1 UAA transporter family Dus PF01207.17 GAX21959.1 - 7.2e-53 179.7 0.0 3e-52 177.7 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) VanW PF04294.13 GAX21959.1 - 0.18 11.5 1.0 0.34 10.6 1.0 1.4 1 0 0 1 1 1 0 VanW like protein MIP PF00230.20 GAX21960.1 - 7.7e-58 195.9 15.0 1e-57 195.5 15.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Carb_anhydrase PF00194.21 GAX21962.1 - 3.3e-18 66.2 0.2 9.5e-14 51.5 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase Rpn9_C PF18261.1 GAX21962.1 - 0.078 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix tRNA_int_endo PF01974.17 GAX21963.1 - 0.00013 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SKN1 PF03935.15 GAX21964.1 - 9.2e-67 225.5 10.6 9.8e-53 179.3 2.1 3.2 3 0 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 GAX21964.1 - 0.0022 18.2 1.5 0.0022 18.2 1.5 2.2 2 0 0 2 2 2 1 EB module EGF_2 PF07974.13 GAX21964.1 - 0.011 16.1 12.6 0.011 16.1 12.6 2.6 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_16 PF00722.21 GAX21964.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 CN_hydrolase PF00795.22 GAX21964.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase 2-Hacid_dh_C PF02826.19 GAX21965.1 - 0.026 13.9 0.0 0.11 11.8 0.0 2.0 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FIST PF08495.10 GAX21965.1 - 0.09 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 FIST N domain HYR PF02494.16 GAX21966.1 - 2.7e-17 62.8 15.5 4.8e-09 36.4 1.0 3.9 4 0 0 4 4 4 2 HYR domain VWA_2 PF13519.6 GAX21966.1 - 1.9e-08 34.9 0.1 4.3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAX21966.1 - 8.5e-07 29.4 1.0 1.6e-06 28.5 0.4 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GAX21966.1 - 0.0014 18.1 0.4 0.0029 17.0 0.4 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein LTD PF00932.19 GAX21967.1 - 1.1e-05 25.7 0.1 5.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Lamin Tail Domain Exo_endo_phos PF03372.23 GAX21967.1 - 0.012 15.1 0.9 0.026 14.0 0.9 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF2193 PF09959.9 GAX21967.1 - 0.15 10.4 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) CytochromB561_N PF09786.9 GAX21968.1 - 0.0083 15.2 2.0 0.0092 15.0 2.0 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal RVT_2 PF07727.14 GAX21971.1 - 3.9e-13 49.6 0.0 6.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.15 GAX21973.1 - 0.043 13.9 0.7 0.32 11.1 0.7 2.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Amino_oxidase PF01593.24 GAX21974.1 - 1.7e-14 54.0 0.0 2.6e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX21974.1 - 1.5e-13 50.8 0.0 3.2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX21974.1 - 1.5e-12 47.8 3.1 1.1e-05 25.2 1.6 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX21974.1 - 5.3e-10 39.0 1.0 2.1e-05 23.8 1.3 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 GAX21974.1 - 1.6e-07 30.4 0.6 0.0047 15.7 0.4 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 GAX21974.1 - 1.4e-05 24.5 2.0 0.00048 19.5 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX21974.1 - 2.2e-05 23.8 0.2 4.1e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 GAX21974.1 - 2.3e-05 24.9 0.2 0.022 15.3 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX21974.1 - 0.00012 21.5 1.0 0.00028 20.4 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAX21974.1 - 0.0015 17.8 0.1 0.0065 15.8 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain GDI PF00996.18 GAX21974.1 - 0.0031 16.1 0.0 0.06 11.9 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor MCRA PF06100.11 GAX21974.1 - 0.088 11.6 0.0 0.19 10.5 0.1 1.5 2 0 0 2 2 2 0 MCRA family Lycopene_cycl PF05834.12 GAX21974.1 - 0.24 10.4 1.3 4.4 6.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 GAX21974.1 - 0.49 9.4 3.9 0.57 9.2 1.7 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A PDZ PF00595.24 GAX21976.1 - 4.7e-07 30.1 0.1 1e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX21976.1 - 0.00041 20.6 0.3 0.001 19.3 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX21976.1 - 0.00077 19.3 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 GAX21976.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Podoplanin PF05808.11 GAX21976.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.7 1 1 2 3 3 3 0 Podoplanin DUF2064 PF09837.9 GAX21980.1 - 5.3e-10 39.2 0.0 1.7e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2064) zf-RING_2 PF13639.6 GAX21981.1 - 8.9e-10 38.7 11.2 1.5e-09 38.0 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX21981.1 - 5.1e-07 29.3 3.6 1.3e-06 28.0 3.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GAX21981.1 - 2.1e-05 24.5 6.1 2.1e-05 24.5 6.1 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX21981.1 - 0.00012 22.0 6.6 0.00018 21.5 4.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 GAX21981.1 - 0.0005 20.2 8.9 0.0015 18.7 8.9 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 GAX21981.1 - 0.0011 18.8 8.7 0.0021 17.9 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX21981.1 - 0.0012 19.0 12.5 0.0044 17.3 12.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX21981.1 - 0.0034 17.2 10.5 0.007 16.2 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SseB PF07179.12 GAX21981.1 - 0.036 14.3 0.5 0.058 13.6 0.5 1.3 1 0 0 1 1 1 0 SseB protein N-terminal domain zf-Nse PF11789.8 GAX21981.1 - 0.2 11.5 2.2 0.42 10.5 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 GAX21981.1 - 0.27 11.2 8.3 0.55 10.2 8.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAX21981.1 - 0.44 10.2 8.8 0.92 9.2 8.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAX21981.1 - 0.89 9.7 9.5 1.9 8.7 9.5 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 GAX21981.1 - 4.4 7.3 9.6 12 5.9 0.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L30 PF00327.20 GAX21982.1 - 7.4e-21 73.8 0.8 1.4e-20 72.9 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 GAX21982.1 - 1e-15 57.7 14.6 1.9e-15 56.9 14.6 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain NAPRTase_N PF17767.1 GAX21983.1 - 9e-34 116.5 0.0 2.1e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 GAX21983.1 - 3.7e-26 91.7 0.0 6.1e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 GAX21983.1 - 1.9e-08 34.3 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family E1-E2_ATPase PF00122.20 GAX21984.1 - 1.9e-43 148.1 0.1 4.6e-43 146.8 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAX21984.1 - 4.6e-35 121.8 0.0 8.9e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAX21984.1 - 6.1e-11 42.6 4.5 3.2e-07 30.7 0.2 3.0 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAX21984.1 - 1.6e-06 28.1 1.3 0.0019 18.0 0.5 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX21984.1 - 0.00086 19.8 0.7 0.0022 18.5 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GARS_C PF02843.16 GAX21984.1 - 0.31 11.4 1.1 7.4 6.9 0.0 3.8 4 1 1 5 5 5 0 Phosphoribosylglycinamide synthetase, C domain S1 PF00575.23 GAX21985.1 - 3.5e-24 84.9 5.2 9.7e-08 32.2 0.4 7.0 6 0 0 6 6 6 4 S1 RNA binding domain DUF2573 PF10835.8 GAX21985.1 - 0.71 10.2 2.1 23 5.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2573) Aminotran_1_2 PF00155.21 GAX21986.1 - 2.1e-20 73.2 0.0 2.8e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GST_C PF00043.25 GAX21988.1 - 2.8e-09 37.1 0.0 4.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX21988.1 - 7.5e-08 32.7 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAX21988.1 - 1.6e-07 31.4 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAX21988.1 - 1.9e-05 24.9 0.0 3.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX21988.1 - 0.0064 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX21988.1 - 0.0067 16.4 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF1336 PF07059.12 GAX21989.1 - 8.6e-10 39.0 0.0 1.2e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Mcm10 PF09332.11 GAX21989.1 - 0.028 13.9 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Methyltransf_11 PF08241.12 GAX21990.1 - 1.4e-07 32.0 0.1 2.3e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX21990.1 - 1.5e-06 28.8 0.1 2.4e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX21990.1 - 3.8e-06 26.8 0.0 5.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX21990.1 - 0.023 15.4 0.0 0.033 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 GAX21992.1 - 2.3e-29 101.0 17.6 4.6e-06 27.3 0.5 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX21992.1 - 1.3e-11 44.6 0.3 0.015 15.6 0.0 5.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX21992.1 - 0.00042 19.8 0.1 0.0088 15.4 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 GAX21992.1 - 0.00047 18.9 0.7 0.6 8.7 0.0 2.6 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX21992.1 - 0.00049 19.2 0.1 4.3 6.2 0.0 3.5 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 GAX21992.1 - 0.0039 17.6 2.8 0.055 14.0 0.0 4.0 5 2 0 5 5 5 1 PQQ-like domain WD40 PF00400.32 GAX21995.1 - 1.6e-31 107.9 14.8 6.8e-10 39.4 0.1 7.9 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX21995.1 - 3.4e-15 56.1 0.0 0.00089 19.5 0.0 5.3 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX21995.1 - 0.00019 21.4 0.0 0.0055 16.6 0.0 2.8 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAX21995.1 - 0.00039 19.2 1.0 0.067 11.8 0.1 3.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX21995.1 - 0.069 12.1 0.0 11 4.9 0.0 3.4 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 GAX21996.1 - 0.0047 16.0 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region bZIP_1 PF00170.21 GAX21997.1 - 1.4e-06 28.3 13.2 1.4e-06 28.3 13.2 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX21997.1 - 0.0002 21.4 16.0 0.00023 21.2 14.1 2.1 2 0 0 2 2 2 1 Basic region leucine zipper OrfB_IS605 PF01385.19 GAX21997.1 - 9.1 6.5 10.9 3 8.1 7.7 1.9 2 0 0 2 2 2 0 Probable transposase SBP_bac_3 PF00497.20 GAX21998.1 - 1e-07 31.6 0.0 5.2e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 EF-hand_8 PF13833.6 GAX21998.1 - 7.5e-05 22.5 0.4 0.00019 21.2 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX21998.1 - 0.0019 18.0 0.1 0.28 11.2 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GAX21998.1 - 0.017 14.6 0.2 0.33 10.6 0.1 2.5 2 0 0 2 2 2 0 EF hand EF-hand_11 PF08976.11 GAX21998.1 - 0.024 15.5 0.0 0.048 14.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain LapA_dom PF06305.11 GAX21998.1 - 1 9.2 3.9 0.22 11.3 0.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2061 PF09834.9 GAX22001.1 - 5e-24 84.5 10.1 1.6e-14 54.2 4.0 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2061) GOLGA2L5 PF15070.6 GAX22001.1 - 0.034 12.8 0.4 0.046 12.4 0.4 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 IncD PF17628.2 GAX22001.1 - 0.56 10.0 5.1 7.6 6.3 0.4 2.2 1 1 0 2 2 2 0 Inclusion membrane protein D Cupin_3 PF05899.12 GAX22002.1 - 3.6e-29 100.3 2.0 5e-29 99.8 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GAX22002.1 - 2.7e-05 23.8 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 GAX22002.1 - 0.0093 15.7 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Sel1 PF08238.12 GAX22003.1 - 4.5e-12 46.2 0.6 0.24 12.1 0.0 7.2 7 0 0 7 7 7 3 Sel1 repeat DNA_alkylation PF08713.11 GAX22003.1 - 0.041 13.6 0.6 0.082 12.6 0.6 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme SET PF00856.28 GAX22004.1 - 3.5e-08 34.0 0.0 2.1e-07 31.5 0.0 2.2 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 GAX22004.1 - 0.065 13.4 0.0 22 5.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RXT2_N PF08595.11 GAX22004.1 - 0.077 13.0 2.3 1.2 9.2 0.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 GAX22004.1 - 0.77 9.4 5.6 1.4 8.6 5.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAX22004.1 - 1.3 8.3 3.2 2.2 7.5 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein TPR_4 PF07721.14 GAX22004.1 - 1.5 9.7 4.4 43 5.2 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C78 PF07910.13 GAX22005.1 - 2e-29 102.6 0.4 3e-29 102.0 0.4 1.3 1 0 0 1 1 1 1 Peptidase family C78 Guanylate_cyc_2 PF09778.9 GAX22005.1 - 0.024 14.0 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Guanylylate cyclase Clat_adaptor_s PF01217.20 GAX22006.1 - 5.4e-36 123.6 2.5 1e-35 122.7 2.5 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain CobT PF06213.12 GAX22007.1 - 0.26 10.7 9.6 0.39 10.1 9.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 GAX22008.1 - 0.028 13.8 15.4 0.036 13.4 15.4 1.1 1 0 0 1 1 1 0 BUD22 Ank_4 PF13637.6 GAX22008.1 - 0.073 13.7 0.0 3.5 8.3 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Mpp10 PF04006.12 GAX22008.1 - 0.076 11.4 12.3 0.11 11.0 12.3 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GAX22009.1 - 5.8 6.2 8.2 7.2 5.9 8.2 1.2 1 0 0 1 1 1 0 SDA1 DUF4239 PF14023.6 GAX22012.1 - 4e-20 72.5 1.0 1.1e-19 71.0 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4239) HSP70 PF00012.20 GAX22013.1 - 3.3e-77 260.1 16.1 4.1e-63 213.5 0.0 4.2 2 2 2 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 GAX22013.1 - 5.6e-12 45.1 4.0 1.9e-09 36.8 0.2 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GAX22013.1 - 2.6e-05 24.0 0.5 8.1e-05 22.4 0.2 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Snf7 PF03357.21 GAX22013.1 - 0.042 13.4 8.2 0.082 12.5 8.2 1.5 1 0 0 1 1 1 0 Snf7 FtsA PF14450.6 GAX22013.1 - 0.17 12.4 1.8 10 6.6 0.0 3.5 3 1 0 3 3 3 0 Cell division protein FtsA ATG_C PF09333.11 GAX22015.1 - 1.6e-15 57.2 0.0 3.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 GAX22015.1 - 2.1e-06 27.8 0.0 8.7e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 GAX22015.1 - 6.9e-05 22.7 0.1 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 GAX22015.1 - 0.0032 17.2 0.1 0.0099 15.6 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Cdh1_DBD_1 PF18196.1 GAX22016.1 - 1.6 9.0 7.6 0.14 12.5 0.8 2.1 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 CENP-C_C PF11699.8 GAX22018.1 - 9.5e-06 25.7 2.3 0.0062 16.7 0.0 3.0 3 0 0 3 3 3 2 Mif2/CENP-C like Cupin_2 PF07883.11 GAX22018.1 - 0.055 13.2 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 Cupin domain Methyltransf_11 PF08241.12 GAX22019.1 - 1.3e-16 61.0 0.0 4.2e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22019.1 - 2.6e-14 53.4 0.0 5.2e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX22019.1 - 2.9e-12 47.1 0.0 8e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22019.1 - 1.4e-10 41.8 0.0 3.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX22019.1 - 5.3e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX22019.1 - 1.3e-06 27.9 0.0 3.2e-06 26.7 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 GAX22019.1 - 0.00034 19.3 0.0 0.00053 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_7 PF03492.15 GAX22019.1 - 0.043 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase N6_N4_Mtase PF01555.18 GAX22019.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA methylase DUF2710 PF10921.8 GAX22020.1 - 0.028 14.8 0.4 0.58 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) Unstab_antitox PF09720.10 GAX22020.1 - 0.03 14.4 0.3 0.15 12.2 0.1 2.3 2 0 0 2 2 2 0 Putative addiction module component Peptidase_M32 PF02074.15 GAX22020.1 - 0.1 11.3 0.9 0.17 10.6 0.1 1.6 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase YabA PF06156.13 GAX22020.1 - 0.11 13.1 6.2 0.69 10.6 3.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA ERM PF00769.19 GAX22020.1 - 0.33 10.7 6.2 0.17 11.7 2.2 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SlyX PF04102.12 GAX22020.1 - 9.8 6.9 11.0 32 5.2 5.8 2.4 2 0 0 2 2 2 0 SlyX PseudoU_synth_2 PF00849.22 GAX22021.1 - 3.3e-20 72.8 0.0 5.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Dna2 PF08696.11 GAX22022.1 - 5.9e-40 137.3 0.0 1.1e-39 136.4 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 GAX22022.1 - 7.2e-34 117.8 0.3 3.6e-16 59.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 GAX22022.1 - 2e-22 79.8 0.0 4.8e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX22022.1 - 6e-17 62.0 0.1 3.2e-16 59.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 GAX22022.1 - 2.1e-10 40.9 0.0 7.7e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.6 GAX22022.1 - 4.7e-10 40.0 0.0 1.4e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 GAX22022.1 - 2.8e-05 24.1 0.0 0.00014 21.8 0.0 2.1 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 GAX22022.1 - 0.0013 18.3 1.4 0.059 12.9 0.0 2.7 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain Cas_Cas4 PF01930.17 GAX22022.1 - 0.0016 18.6 0.0 0.0059 16.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 GAX22022.1 - 0.0026 17.5 0.1 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 GAX22022.1 - 0.018 14.7 0.2 0.57 9.8 0.1 2.3 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAX22022.1 - 0.023 15.1 0.0 0.097 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 GAX22022.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 GAX22022.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 GAX22022.1 - 0.15 12.0 0.0 1.5 8.8 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit GTP1_OBG PF01018.22 GAX22023.1 - 1.6e-36 125.3 0.8 1.3e-27 96.4 0.7 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 GAX22023.1 - 1e-22 80.3 0.0 3.3e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX22023.1 - 2e-07 30.7 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 GAX22023.1 - 4.9e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family cobW PF02492.19 GAX22023.1 - 0.048 13.3 0.0 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GAX22023.1 - 0.11 13.0 0.1 1.3 9.5 0.0 2.5 3 0 0 3 3 3 0 ABC transporter AAA_18 PF13238.6 GAX22023.1 - 0.18 12.3 1.1 4.5 7.8 0.0 3.1 3 1 0 3 3 3 0 AAA domain DBR1 PF05011.13 GAX22024.1 - 4.9e-25 88.6 0.0 2.7e-24 86.2 0.0 2.1 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain FoP_duplication PF13865.6 GAX22024.1 - 4.9 7.8 5.3 9.6 6.8 5.3 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RNase_HII PF01351.18 GAX22026.1 - 5e-28 98.3 0.1 1.4e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII RuBisCO_large PF00016.20 GAX22026.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Sec1 PF00995.23 GAX22027.1 - 3.4e-106 356.8 0.0 3.8e-106 356.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family VapB_antitoxin PF09957.9 GAX22027.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB Tox-REase-7 PF15649.6 GAX22027.1 - 0.16 12.3 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 CRAL_TRIO PF00650.20 GAX22028.1 - 1.2e-14 54.4 0.0 1.7e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Exosortase_EpsH PF09721.10 GAX22028.1 - 0.042 13.4 0.6 0.071 12.6 0.6 1.3 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) COPI_assoc PF08507.10 GAX22029.1 - 0.62 10.1 14.7 0.084 12.9 9.4 2.2 2 1 1 3 3 3 0 COPI associated protein Rad51 PF08423.11 GAX22030.1 - 8.5e-24 84.2 0.1 6.8e-22 77.9 0.1 2.1 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 GAX22030.1 - 7.2e-08 32.2 0.1 3.2e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 GAX22030.1 - 1.3e-07 31.2 0.1 5.3e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 GAX22030.1 - 2e-06 27.5 0.1 6.5e-06 25.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAX22030.1 - 1.1e-05 24.9 0.2 0.00014 21.3 0.2 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ABC_tran PF00005.27 GAX22030.1 - 0.00061 20.3 0.0 0.00094 19.7 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 GAX22030.1 - 0.0009 19.0 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 GAX22030.1 - 0.0014 17.6 0.2 0.0021 17.0 0.2 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.16 GAX22030.1 - 0.0061 16.0 0.3 0.01 15.3 0.3 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.6 GAX22030.1 - 0.013 15.7 0.1 0.031 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX22030.1 - 0.026 14.4 0.0 0.064 13.2 0.1 1.6 2 0 0 2 2 2 0 NACHT domain CP_ATPgrasp_1 PF04174.13 GAX22030.1 - 0.035 13.1 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 A circularly permuted ATPgrasp AAA_16 PF13191.6 GAX22030.1 - 0.058 13.8 0.1 0.096 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 GAX22030.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 GAX22030.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 GAX22030.1 - 0.12 12.0 0.1 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein LOR PF04525.12 GAX22031.1 - 0.0046 16.6 0.0 0.0083 15.7 0.0 1.4 1 1 0 1 1 1 1 LURP-one-related Aa_trans PF01490.18 GAX22033.1 - 3.6e-46 157.7 22.2 5e-46 157.2 22.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF677 PF05055.12 GAX22033.1 - 0.11 11.4 0.2 0.18 10.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) PRAI PF00697.22 GAX22035.1 - 0.0091 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Metallophos_2 PF12850.7 GAX22036.1 - 5.3e-19 69.0 0.1 6.7e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GAX22036.1 - 0.00032 21.3 0.0 0.98 9.9 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase HYR PF02494.16 GAX22037.1 - 0.0013 19.0 22.8 1.3 9.4 1.4 5.2 4 1 0 4 4 4 4 HYR domain TMEM52 PF14979.6 GAX22037.1 - 4.2 7.3 6.8 22 5.0 0.2 3.3 3 0 0 3 3 3 0 Transmembrane 52 ABC_tran PF00005.27 GAX22038.1 - 9.4e-36 123.3 0.0 4.3e-17 62.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 GAX22038.1 - 1.9e-12 46.8 5.0 4.8e-12 45.5 5.0 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 GAX22038.1 - 1e-11 45.2 3.4 0.033 14.0 0.0 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX22038.1 - 1.3e-11 44.3 0.5 0.00022 20.7 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX22038.1 - 5.1e-07 29.7 0.0 0.0059 16.4 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 GAX22038.1 - 6.9e-07 29.8 0.0 0.0018 18.7 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.27 GAX22038.1 - 1.5e-06 27.7 3.9 1.5e-06 27.7 3.9 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 GAX22038.1 - 1.2e-05 25.7 0.0 0.055 13.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX22038.1 - 3.1e-05 24.3 0.0 0.0094 16.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX22038.1 - 3.5e-05 23.8 1.2 0.0059 16.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 GAX22038.1 - 3.7e-05 23.4 0.2 0.29 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.7 GAX22038.1 - 5.3e-05 23.1 3.0 5.3e-05 23.1 3.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 GAX22038.1 - 5.4e-05 23.2 0.1 0.28 11.1 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_24 PF13479.6 GAX22038.1 - 0.00013 21.7 1.0 0.13 12.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 GAX22038.1 - 0.00017 22.1 7.1 0.00097 19.7 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.22 GAX22038.1 - 0.00037 20.2 1.8 0.084 12.5 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 GAX22038.1 - 0.00072 20.1 0.9 0.053 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 GAX22038.1 - 0.00073 19.6 11.5 0.0017 18.5 11.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 GAX22038.1 - 0.00081 19.4 0.1 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 GAX22038.1 - 0.0016 18.4 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 GAX22038.1 - 0.0016 18.8 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 GAX22038.1 - 0.0018 18.3 0.3 0.093 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_2 PF12797.7 GAX22038.1 - 0.0025 17.8 1.1 0.0025 17.8 1.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 GAX22038.1 - 0.0028 17.8 1.5 0.0028 17.8 1.5 1.9 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAX22038.1 - 0.0035 18.2 6.5 0.013 16.5 0.2 2.7 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_18 PF13238.6 GAX22038.1 - 0.0039 17.7 0.0 4.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAX22038.1 - 0.004 17.4 0.2 1.5 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX22038.1 - 0.0059 16.3 2.8 0.37 10.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 GAX22038.1 - 0.007 16.6 0.1 1.3 9.3 0.0 3.2 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit Fer4_10 PF13237.6 GAX22038.1 - 0.0089 16.1 1.7 0.0089 16.1 1.7 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_33 PF13671.6 GAX22038.1 - 0.011 15.8 0.4 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 GAX22038.1 - 0.013 15.3 0.0 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E AAA_7 PF12775.7 GAX22038.1 - 0.031 13.8 0.3 3 7.3 0.0 3.3 4 0 0 4 4 3 0 P-loop containing dynein motor region NB-ARC PF00931.22 GAX22038.1 - 0.035 13.3 0.1 4.4 6.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Thymidylate_kin PF02223.17 GAX22038.1 - 0.04 13.6 0.1 13 5.4 0.1 2.6 2 0 0 2 2 2 0 Thymidylate kinase Fer4_17 PF13534.6 GAX22038.1 - 0.041 14.4 0.3 0.041 14.4 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 GAX22038.1 - 0.042 13.7 1.4 0.94 9.4 0.0 2.8 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 GAX22038.1 - 0.087 12.9 0.1 20 5.3 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 GAX22038.1 - 0.091 12.8 0.0 13 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_13 PF13166.6 GAX22038.1 - 0.1 11.2 0.2 0.2 10.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAX22038.1 - 0.11 12.9 0.7 0.76 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 GAX22038.1 - 0.14 11.4 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain DUF815 PF05673.13 GAX22038.1 - 0.16 11.1 0.1 7.6 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 GAX22038.1 - 0.17 10.9 0.6 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 GAX22038.1 - 0.2 11.9 1.2 1.6 9.0 0.0 2.6 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Fer4_8 PF13183.6 GAX22038.1 - 2.9 8.4 12.4 0.56 10.7 1.5 2.6 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 GAX22038.1 - 3.6 8.3 16.7 0.49 11.0 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain SH3_3 PF08239.11 GAX22040.1 - 0.0025 18.0 0.5 0.02 15.2 0.2 2.7 3 0 0 3 3 3 1 Bacterial SH3 domain SCNM1_acidic PF15805.5 GAX22040.1 - 0.18 11.6 1.5 2.1 8.2 0.4 2.5 2 0 0 2 2 2 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 2OG-FeII_Oxy PF03171.20 GAX22041.1 - 1.5e-09 38.3 0.0 2.9e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAX22041.1 - 1.7e-09 38.4 0.0 4.4e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Mac PF12464.8 GAX22041.1 - 0.11 12.7 0.0 3.5 7.9 0.0 2.7 2 0 0 2 2 2 0 Maltose acetyltransferase FG-GAP_2 PF14312.6 GAX22042.1 - 5.9 7.2 23.7 0.65 10.3 0.7 6.4 6 1 0 6 6 6 0 FG-GAP repeat N2227 PF07942.12 GAX22043.1 - 8.3e-76 254.7 0.0 1.1e-36 126.5 0.0 2.2 2 0 0 2 2 2 2 N2227-like protein Methyltransf_23 PF13489.6 GAX22043.1 - 5.3e-05 23.1 0.0 0.0002 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22043.1 - 8.5e-05 23.1 0.0 0.015 15.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22043.1 - 9.7e-05 23.0 0.0 0.00052 20.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Pex26 PF07163.12 GAX22043.1 - 0.063 12.6 0.4 0.09 12.1 0.4 1.2 1 0 0 1 1 1 0 Pex26 protein B5 PF03484.15 GAX22043.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetase B5 domain PDZ PF00595.24 GAX22044.1 - 1.2e-09 38.4 0.0 2.7e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 GAX22044.1 - 1.3e-09 37.7 0.0 2.9e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX22044.1 - 8.6e-05 22.8 0.0 0.0037 17.6 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PT-HINT PF07591.11 GAX22044.1 - 0.028 14.7 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Pretoxin HINT domain PPR_2 PF13041.6 GAX22045.1 - 3.2e-12 46.4 5.0 0.18 12.0 0.0 7.2 6 2 2 8 8 8 5 PPR repeat family PPR_3 PF13812.6 GAX22045.1 - 4.1e-10 39.6 0.2 0.01 15.9 0.0 6.4 4 3 1 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX22045.1 - 3.9e-05 23.3 0.0 1.3 8.8 0.0 5.5 5 0 0 5 5 5 2 PPR repeat PPR PF01535.20 GAX22045.1 - 0.0089 16.2 15.5 8.8 6.8 0.0 8.8 10 2 0 10 10 10 1 PPR repeat IcmF-related PF06761.12 GAX22045.1 - 0.013 15.0 0.9 7.4 5.9 0.0 3.5 3 1 1 4 4 4 0 Intracellular multiplication and human macrophage-killing TipAS PF07739.13 GAX22045.1 - 0.25 11.9 5.4 1.3 9.6 0.9 3.5 2 2 1 3 3 3 0 TipAS antibiotic-recognition domain RsbRD_N PF14361.6 GAX22045.1 - 7.9 7.2 6.3 12 6.6 0.0 3.8 4 1 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain ECH_2 PF16113.5 GAX22046.1 - 0.018 14.5 3.9 0.019 14.5 3.9 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Peptidase_M22 PF00814.25 GAX22047.1 - 2.4e-79 266.8 0.0 2.9e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 GAX22047.1 - 1.5e-06 28.1 0.0 3.3e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus Hydrolase_4 PF12146.8 GAX22049.1 - 1.2e-33 116.3 0.0 3.8e-33 114.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX22049.1 - 6.2e-14 53.1 0.1 8.9e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX22049.1 - 2.6e-08 33.8 0.0 6.5e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAX22049.1 - 0.00011 22.1 0.0 1.2 8.9 0.0 3.3 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAX22049.1 - 0.00058 19.4 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAX22049.1 - 0.0008 19.1 0.0 0.0034 17.0 0.0 2.0 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 GAX22049.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1539 PF07560.11 GAX22051.1 - 0.039 14.0 4.5 0.74 9.9 0.6 3.5 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) Peptidase_S64 PF08192.11 GAX22051.1 - 8.2 4.8 7.2 2.5 6.5 0.4 2.0 2 0 0 2 2 2 0 Peptidase family S64 RNA_pol_Rpc4 PF05132.14 GAX22052.1 - 1.3e-16 61.4 0.3 1.3e-16 61.4 0.3 3.5 3 1 0 3 3 3 1 RNA polymerase III RPC4 Peptidase_C1 PF00112.23 GAX22053.1 - 3.3e-39 135.2 2.1 4.4e-39 134.8 2.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAX22053.1 - 0.012 14.4 0.8 0.027 13.2 0.5 1.6 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 GAX22055.1 - 3e-39 135.3 1.7 4.8e-39 134.7 1.7 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAX22055.1 - 0.0062 15.4 0.8 0.011 14.5 0.5 1.5 2 0 0 2 2 2 1 Peptidase C1-like family Maf PF02545.14 GAX22057.1 - 2e-28 99.4 0.0 2.6e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Aldo_ket_red PF00248.21 GAX22058.1 - 8.5e-16 58.0 0.0 1.3e-11 44.2 0.0 2.2 1 1 1 2 2 2 2 Aldo/keto reductase family XPC-binding PF09280.11 GAX22058.1 - 0.066 12.9 0.1 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 XPC-binding domain tRNA_int_endo PF01974.17 GAX22059.1 - 8.2e-21 73.9 0.5 1.4e-20 73.1 0.1 1.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain Mrr_cat PF04471.12 GAX22059.1 - 0.014 15.5 0.1 0.66 10.0 0.0 2.0 1 1 1 2 2 2 0 Restriction endonuclease RPE65 PF03055.15 GAX22060.1 - 2.3e-71 241.4 0.0 2.7e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein HA PF03457.14 GAX22061.1 - 3.3e-86 283.6 31.8 1.6e-19 70.0 0.1 6.2 6 0 0 6 6 6 6 Helicase associated domain Glyco_trans_4_5 PF16994.5 GAX22061.1 - 0.11 12.1 1.9 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Glycosyl-transferase family 4 DnaJ PF00226.31 GAX22062.1 - 2e-26 91.9 0.9 4.6e-26 90.7 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3485 PF11984.8 GAX22062.1 - 0.15 11.7 0.4 6 6.5 0.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3485) HMG_box PF00505.19 GAX22063.1 - 2.8e-10 40.5 0.3 1.1e-06 28.9 0.6 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX22063.1 - 5.5e-06 26.9 0.4 0.00015 22.3 0.5 2.4 2 0 0 2 2 2 1 HMG-box domain Ank_2 PF12796.7 GAX22064.1 - 4.3e-10 40.0 1.0 5.6e-05 23.7 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX22064.1 - 2e-09 37.5 1.6 0.0006 20.0 0.2 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX22064.1 - 1.1e-08 34.6 0.5 0.54 11.0 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 GAX22064.1 - 1.3e-07 32.0 0.1 0.023 15.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX22064.1 - 5.3e-06 26.6 2.6 1.8 9.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Phage_tail_X PF05489.12 GAX22064.1 - 0.0054 16.4 0.2 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 Phage Tail Protein X BAT PF15915.5 GAX22064.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 GAF and HTH_10 associated domain CS PF04969.16 GAX22065.1 - 4.6e-11 43.6 0.1 7.6e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 CS domain SGS PF05002.15 GAX22065.1 - 0.0059 16.7 1.6 0.014 15.5 1.6 1.6 1 0 0 1 1 1 1 SGS domain Hc1 PF07432.13 GAX22065.1 - 0.014 15.8 0.4 0.014 15.8 0.4 1.8 2 0 0 2 2 2 0 Histone H1-like protein Hc1 MRP-S22 PF10245.9 GAX22066.1 - 0.018 14.8 2.0 0.022 14.5 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 Phlebovirus_NSM PF07246.11 GAX22066.1 - 0.14 11.6 3.0 0.16 11.3 3.0 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Mito_carr PF00153.27 GAX22067.1 - 4.5e-67 222.0 3.2 2.3e-21 75.5 0.0 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein EutK_C PF16365.5 GAX22067.1 - 0.0012 18.8 0.0 0.15 12.1 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilization protein EutK C-terminus Serine_protease PF18405.1 GAX22067.1 - 0.022 13.9 0.6 1.8 7.7 0.0 3.1 2 1 0 3 3 3 0 Gammaproteobacterial serine protease RebB PF11747.8 GAX22067.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Killing trait DUF3082 PF11282.8 GAX22069.1 - 1.2e-20 73.5 6.6 1.9e-20 72.9 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) BON PF04972.17 GAX22069.1 - 0.065 13.5 1.2 0.1 12.9 0.3 1.7 2 0 0 2 2 2 0 BON domain CS PF04969.16 GAX22070.1 - 1.8e-15 57.7 0.0 4.7e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 GAX22070.1 - 3.1e-12 46.3 0.0 6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Trp_syntA PF00290.20 GAX22071.1 - 1e-83 280.2 0.2 1.9e-83 279.3 0.2 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 GAX22071.1 - 1.5e-46 159.2 4.4 1.5e-46 159.2 2.4 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 GAX22071.1 - 0.0018 17.8 0.0 0.0089 15.5 0.0 2.1 2 1 0 3 3 3 1 Histidine biosynthesis protein DUF1971 PF09313.11 GAX22071.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) DUF2547 PF10818.8 GAX22072.1 - 0.054 14.4 0.0 0.06 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Skp1_POZ PF03931.15 GAX22073.1 - 3.7e-10 39.8 0.3 6.4e-10 39.1 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 GAX22073.1 - 2.5e-08 33.9 0.0 5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain PUA_3 PF17785.1 GAX22073.1 - 0.061 13.1 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 PUA-like domain Skp1_POZ PF03931.15 GAX22074.1 - 2.7e-07 30.7 0.2 9.1e-07 29.0 0.2 1.9 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 GAX22074.1 - 0.011 15.8 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 0 Skp1 family, dimerisation domain PT PF04886.12 GAX22075.1 - 3.5e-06 26.5 50.0 3.5e-05 23.3 17.3 3.9 2 1 1 3 3 3 2 PT repeat Dicty_CTDC PF00526.18 GAX22075.1 - 0.0047 16.8 0.2 0.0047 16.8 0.2 4.3 5 0 0 5 5 5 1 Dictyostelium (slime mold) repeat DUF4585 PF15232.6 GAX22075.1 - 9.4 6.4 6.9 4.1 7.5 2.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4585) Pkinase PF00069.25 GAX22076.1 - 4.7e-24 85.2 0.0 8.1e-24 84.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22076.1 - 1.3e-08 34.5 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAF-AH_p_II PF03403.13 GAX22077.1 - 7.8e-07 27.9 0.2 0.00011 20.9 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GAX22077.1 - 9e-06 24.8 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 GAX22077.1 - 3.8e-05 24.4 0.3 5.6e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 GAX22077.1 - 0.00014 21.0 0.0 0.0003 19.9 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase PLAC8 PF04749.17 GAX22078.1 - 1.4e-12 48.5 10.4 2.7e-12 47.6 10.4 1.5 1 0 0 1 1 1 1 PLAC8 family Prenyltrans PF00432.21 GAX22078.1 - 8.3 6.2 9.9 16 5.4 3.0 2.7 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Ribonuclease_3 PF00636.26 GAX22080.1 - 1.5e-16 60.9 0.0 7.8e-08 32.9 0.0 3.1 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAX22080.1 - 4.1e-10 39.9 0.0 0.00018 21.7 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease-III-like PAZ PF02170.22 GAX22080.1 - 6.6e-10 38.9 0.1 1.9e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 PAZ domain Dicer_dimer PF03368.14 GAX22080.1 - 0.1 12.8 0.0 0.75 10.0 0.0 2.3 2 0 0 2 2 2 0 Dicer dimerisation domain Metallophos PF00149.28 GAX22081.1 - 1.1e-31 110.9 0.0 1.8e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 GAX22081.1 - 5.7e-07 29.9 0.4 1.3e-06 28.7 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX22081.1 - 0.00015 21.1 0.2 0.032 13.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX22081.1 - 0.00026 20.7 0.6 0.065 13.2 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 GAX22081.1 - 0.0032 17.3 0.2 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 GAX22081.1 - 0.0047 17.2 0.0 0.0087 16.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain THB PF18362.1 GAX22081.1 - 0.06 13.0 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Tri-helix bundle domain Itfg2 PF15907.5 GAX22082.1 - 0.13 11.3 0.1 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 zf-C3HC4_3 PF13920.6 GAX22083.1 - 4.1e-08 32.9 10.8 7e-08 32.2 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX22083.1 - 0.0036 17.0 0.4 0.0082 15.9 0.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger YopD PF05844.12 GAX22083.1 - 0.037 13.0 0.3 0.059 12.4 0.3 1.2 1 0 0 1 1 1 0 YopD protein zf-RING_UBOX PF13445.6 GAX22083.1 - 0.042 13.9 10.1 0.086 12.9 10.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF4072 PF13284.6 GAX22083.1 - 0.071 13.6 0.8 3.1 8.3 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) DUF2913 PF11140.8 GAX22083.1 - 0.078 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) WD40 PF00400.32 GAX22084.1 - 8.6e-17 61.2 20.5 0.0055 17.5 0.7 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX22084.1 - 1.4e-08 34.9 3.7 0.0061 16.8 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX22084.1 - 0.00093 18.2 0.1 3.3 6.6 0.0 3.3 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Elongin_A PF06881.11 GAX22085.1 - 0.0033 17.9 4.2 0.23 12.0 2.8 2.5 2 0 0 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 GAX22085.1 - 0.065 13.3 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 TFIIS helical bundle-like domain DEAD PF00270.29 GAX22086.1 - 5.7e-49 166.3 0.0 9.2e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX22086.1 - 1.4e-30 105.9 0.0 6e-30 103.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX22086.1 - 2.2e-07 31.1 0.0 4.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 GAX22089.1 - 6.7e-70 235.5 0.0 8.5e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22089.1 - 3e-30 105.4 0.0 4.3e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAX22089.1 - 1.9e-07 31.7 0.3 6.1e-07 30.0 0.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAX22089.1 - 1.2e-05 24.8 0.0 0.019 14.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like PX PF00787.24 GAX22089.1 - 9.9e-05 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 PX domain FTA2 PF13095.6 GAX22089.1 - 0.0046 16.6 0.0 0.069 12.8 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAX22089.1 - 0.03 13.3 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GAX22089.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Methyltransf_25 PF13649.6 GAX22090.1 - 9.8e-13 48.6 0.0 1.8e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22090.1 - 9.3e-10 39.1 0.0 1.5e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22090.1 - 1.6e-09 37.8 0.0 2.8e-09 37.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22090.1 - 1.6e-09 38.3 0.0 2.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX22090.1 - 2.7e-06 26.9 0.1 5.1e-06 26.0 0.1 1.4 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAX22090.1 - 8.5e-06 25.6 0.1 1.2e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 GAX22090.1 - 0.0025 17.0 0.0 0.0034 16.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme NodS PF05401.11 GAX22090.1 - 0.035 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) P_C10 PF14974.6 GAX22091.1 - 1.1e-06 28.7 1.0 1.3e-05 25.2 0.1 2.4 2 1 0 2 2 2 1 Protein C10 EGF_CA PF07645.15 GAX22092.1 - 6.4e-10 39.1 16.1 1.1e-08 35.1 2.0 7.5 6 2 1 7 7 7 2 Calcium-binding EGF domain EGF_3 PF12947.7 GAX22092.1 - 1.3e-08 34.9 22.8 7.7e-05 22.8 0.9 6.9 9 0 0 9 9 9 3 EGF domain EGF PF00008.27 GAX22092.1 - 8.7e-05 22.7 54.5 0.0017 18.6 2.4 7.2 6 1 0 6 6 6 3 EGF-like domain cEGF PF12662.7 GAX22092.1 - 0.00031 20.6 0.4 0.00031 20.6 0.4 6.9 8 0 0 8 8 8 1 Complement Clr-like EGF-like hEGF PF12661.7 GAX22092.1 - 0.00036 21.1 11.0 0.00057 20.4 1.8 7.4 7 0 0 7 7 7 3 Human growth factor-like EGF FXa_inhibition PF14670.6 GAX22092.1 - 0.023 15.0 1.6 0.023 15.0 1.6 7.3 8 1 1 9 9 9 0 Coagulation Factor Xa inhibitory site DUF5011 PF16403.5 GAX22092.1 - 0.078 13.1 0.8 1.4 9.0 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5011) TraP PF07296.11 GAX22092.1 - 0.43 9.7 3.7 0.092 11.9 0.1 1.6 2 0 0 2 2 2 0 TraP protein CCDC50_N PF15295.6 GAX22093.1 - 0.0023 18.1 3.7 0.42 10.8 0.5 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 50 N-terminus Lectin_N PF03954.14 GAX22093.1 - 0.0074 16.0 0.2 5.1 6.8 0.2 2.3 2 0 0 2 2 2 2 Hepatic lectin, N-terminal domain CUE PF02845.16 GAX22093.1 - 0.025 14.3 0.0 0.13 11.9 0.0 2.3 1 1 0 1 1 1 0 CUE domain His_Phos_2 PF00328.22 GAX22094.1 - 5.9e-15 55.5 0.0 1.8e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Transcrip_act PF04949.13 GAX22095.1 - 0.023 14.6 1.0 0.039 13.8 1.0 1.3 1 0 0 1 1 1 0 Transcriptional activator DD_K PF12121.8 GAX22095.1 - 0.54 10.4 6.7 0.32 11.2 0.4 2.5 2 0 0 2 2 2 0 Dermaseptin GPS2_interact PF15784.5 GAX22095.1 - 1.2 9.7 3.3 1.8 9.1 0.0 2.9 4 0 0 4 4 4 0 G-protein pathway suppressor 2-interacting domain NAD_binding_5 PF07994.12 GAX22096.1 - 1.5e-58 198.7 0.0 2.3e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAX22096.1 - 4.2e-24 84.9 0.0 7.8e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase PfkB PF00294.24 GAX22096.1 - 6.5e-13 48.7 0.7 8.7e-12 44.9 0.7 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HMG_box PF00505.19 GAX22096.1 - 0.00013 22.3 1.1 0.00041 20.7 0.7 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX22096.1 - 0.0021 18.6 1.1 0.0043 17.6 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain CARDB PF07705.11 GAX22097.1 - 0.14 12.4 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 CARDB HLH PF00010.26 GAX22098.1 - 0.00072 19.5 2.6 0.0023 17.9 2.8 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.6 GAX22098.1 - 0.033 14.6 1.7 0.061 13.7 1.7 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 eIF3_subunit PF08597.10 GAX22098.1 - 0.046 13.6 1.0 0.074 13.0 1.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FXR_C1 PF16096.5 GAX22098.1 - 7.5 6.8 9.9 8.3 6.7 2.8 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 bZIP_1 PF00170.21 GAX22099.1 - 1.2e-09 38.1 13.7 3.2e-09 36.7 13.7 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX22099.1 - 8.1e-06 25.8 17.3 2.5e-05 24.3 17.3 1.9 1 0 0 1 1 1 1 Basic region leucine zipper DUF3584 PF12128.8 GAX22099.1 - 0.035 11.7 12.6 0.066 10.7 12.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ANAPC15 PF15243.6 GAX22099.1 - 0.079 13.4 2.9 0.56 10.6 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Atg14 PF10186.9 GAX22099.1 - 0.085 11.9 5.5 0.23 10.5 5.5 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIA PF03153.13 GAX22099.1 - 0.26 11.3 18.6 0.37 10.7 18.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HemX PF04375.14 GAX22099.1 - 7.9 5.7 18.4 0.065 12.5 8.2 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Lipase_3 PF01764.25 GAX22100.1 - 1.3e-16 60.8 0.0 3.6e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Pheromone PF08015.11 GAX22100.1 - 0.066 14.3 0.0 0.31 12.1 0.0 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Bromodomain PF00439.25 GAX22101.1 - 1.7e-12 47.2 0.0 4.3e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 GAX22101.1 - 7.8e-06 26.2 0.1 7.8e-06 26.2 0.1 2.9 2 1 0 2 2 2 1 PWWP domain Chloroa_b-bind PF00504.21 GAX22102.1 - 5.1e-40 137.6 0.0 6.7e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ABC2_membrane PF01061.24 GAX22103.1 - 4e-35 121.2 19.9 6.8e-35 120.4 19.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX22103.1 - 4.4e-23 82.3 0.0 6.6e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX22103.1 - 5.2e-08 32.4 15.6 7.4e-08 31.9 15.6 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAX22103.1 - 0.00012 22.0 0.1 0.73 9.6 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAX22103.1 - 0.00029 20.8 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GAX22103.1 - 0.0033 17.5 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX22103.1 - 0.0034 17.8 0.0 0.0062 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GAX22103.1 - 0.048 13.4 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 GAX22103.1 - 0.084 12.3 0.0 0.7 9.3 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 GAX22103.1 - 0.097 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.6 GAX22103.1 - 0.099 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX22103.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX22103.1 - 0.22 12.0 0.0 0.34 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Nop16 PF09420.10 GAX22104.1 - 7e-19 68.7 7.5 2.5e-12 47.3 0.3 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Dor1 PF04124.12 GAX22105.1 - 5.9e-33 114.0 14.8 4.5e-32 111.1 12.1 2.5 2 1 0 2 2 2 1 Dor1-like family Sec5 PF15469.6 GAX22105.1 - 2e-05 24.5 0.0 4.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Exo84_C PF16528.5 GAX22105.1 - 0.0033 17.3 4.1 0.11 12.3 0.3 3.1 2 1 1 3 3 3 2 Exocyst component 84 C-terminal Baculo_PEP_C PF04513.12 GAX22105.1 - 0.078 13.0 2.7 0.63 10.1 0.1 3.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SIR2 PF02146.17 GAX22106.1 - 5.1e-34 117.7 0.0 7.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAX22106.1 - 8.4e-06 25.6 0.0 0.15 11.8 0.0 2.5 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain CutC PF03932.14 GAX22106.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 CutC family zf-NADH-PPase PF09297.11 GAX22106.1 - 6.6 6.5 7.2 11 5.8 0.3 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Presenilin PF01080.17 GAX22107.1 - 1.8e-111 372.8 1.9 9.2e-72 242.0 3.2 2.0 2 0 0 2 2 2 2 Presenilin CitMHS PF03600.16 GAX22107.1 - 0.028 13.6 3.4 0.31 10.2 3.5 2.5 1 1 0 1 1 1 0 Citrate transporter FAM60A PF15396.6 GAX22107.1 - 0.063 13.3 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A FAM177 PF14774.6 GAX22107.1 - 0.43 11.0 2.0 4.2 7.8 0.7 2.7 3 1 0 3 3 3 0 FAM177 family SUIM_assoc PF16619.5 GAX22107.1 - 5.4 7.2 9.8 67 3.7 0.0 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 UPF0029 PF01205.19 GAX22108.1 - 3e-28 98.2 0.0 4.1e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 EFG_C PF00679.24 GAX22108.1 - 0.00044 20.2 0.0 0.00069 19.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF1949 PF09186.11 GAX22108.1 - 0.034 14.0 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) Chloroa_b-bind PF00504.21 GAX22109.1 - 1e-28 100.9 0.1 1.6e-28 100.2 0.0 1.4 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Ribosomal_S3Ae PF01015.18 GAX22110.1 - 2.6e-40 138.2 1.5 3e-40 138.0 1.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 GAX22110.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region CRAL_TRIO PF00650.20 GAX22111.1 - 9.7e-16 57.9 0.2 1.4e-15 57.4 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX22111.1 - 2.8e-07 30.8 0.0 1.6e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RsfS PF02410.15 GAX22112.1 - 7.3e-16 58.4 1.7 1.8e-15 57.2 0.0 2.4 3 0 0 3 3 3 1 Ribosomal silencing factor during starvation PrsW-protease PF13367.6 GAX22113.1 - 0.18 11.2 2.2 0.15 11.5 0.2 1.8 2 1 0 2 2 2 0 PrsW family intramembrane metalloprotease Hid1 PF12722.7 GAX22113.1 - 6.2 4.8 13.3 11 4.0 13.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 GAX22113.1 - 9 5.0 12.2 14 4.3 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TerY_C PF15616.6 GAX22115.1 - 0.17 12.0 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain tRNA-synt_2d PF01409.20 GAX22116.1 - 1.5e-90 303.0 0.1 2.1e-90 302.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_bind PF01588.20 GAX22116.1 - 4.4e-22 78.0 0.0 9.2e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Phe_tRNA-synt_N PF02912.18 GAX22116.1 - 1.1e-16 60.5 2.8 1.5e-16 60.0 1.1 2.1 1 1 1 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain Mst1_SARAH PF11629.8 GAX22116.1 - 0.12 12.4 0.6 0.43 10.7 0.1 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 FlgN PF05130.12 GAX22116.1 - 1.5 9.4 5.4 0.54 10.8 0.3 2.1 2 0 0 2 2 2 0 FlgN protein SIR2 PF02146.17 GAX22117.1 - 2.3e-48 164.5 0.0 2.1e-46 158.1 0.0 2.9 1 1 0 1 1 1 1 Sir2 family ZZ PF00569.17 GAX22117.1 - 4e-10 39.3 9.0 4e-10 39.3 9.0 2.0 2 0 0 2 2 2 1 Zinc finger, ZZ type Skp1_POZ PF03931.15 GAX22118.1 - 1.7e-17 63.4 1.5 3.7e-17 62.2 1.5 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 GAX22118.1 - 5.2e-16 58.5 0.1 5.2e-16 58.5 0.1 2.4 2 1 0 2 2 2 1 Skp1 family, dimerisation domain BTB PF00651.31 GAX22118.1 - 6.7e-05 23.1 0.1 0.0063 16.7 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain IFT46_B_C PF12317.8 GAX22118.1 - 0.013 15.2 0.3 0.018 14.8 0.3 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF3246 PF11596.8 GAX22118.1 - 0.05 13.0 1.1 0.058 12.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SLM4 PF16818.5 GAX22118.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein SLM4 DUF4611 PF15387.6 GAX22118.1 - 0.19 11.9 4.1 0.16 12.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AMP-binding PF00501.28 GAX22119.1 - 8.4e-93 311.3 0.0 1.1e-92 310.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAX22119.1 - 1.4e-07 32.4 0.0 3.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TP6A_N PF04406.14 GAX22120.1 - 5.4e-21 74.3 0.1 1.1e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Pkinase PF00069.25 GAX22121.1 - 2.2e-60 204.2 0.1 5.2e-60 203.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 GAX22121.1 - 9.7e-53 176.2 0.1 2.6e-19 69.1 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX22121.1 - 5.7e-28 97.9 0.0 9.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX22121.1 - 0.0023 17.9 0.4 0.007 16.3 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX22121.1 - 0.0078 15.6 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAX22121.1 - 0.039 12.7 0.2 1.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 GAX22121.1 - 0.17 11.2 0.1 0.36 10.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cupin_2 PF07883.11 GAX22121.1 - 0.2 11.4 2.4 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Cupin domain DUF2201_N PF13203.6 GAX22121.1 - 0.25 10.9 1.5 0.39 10.3 1.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain ALMT PF11744.8 GAX22121.1 - 4.9 5.9 5.1 7.1 5.3 5.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Tim17 PF02466.19 GAX22122.1 - 2e-30 105.4 6.0 2.7e-30 105.0 6.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HSP70 PF00012.20 GAX22123.1 - 1.1e-264 879.2 4.1 1.3e-264 879.0 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAX22123.1 - 1.7e-16 60.0 0.1 1.5e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 GAX22123.1 - 0.015 14.3 0.1 0.063 12.3 0.1 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain PilM_2 PF11104.8 GAX22123.1 - 0.017 14.2 0.1 2.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.18 GAX22123.1 - 0.061 12.6 0.2 0.13 11.5 0.2 1.6 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase LRR_6 PF13516.6 GAX22124.1 - 5.7e-24 82.1 15.7 0.0068 16.4 0.1 11.1 11 0 0 11 11 11 6 Leucine Rich repeat Response_reg PF00072.24 GAX22124.1 - 9.2e-18 64.5 0.1 3.2e-17 62.7 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 GAX22124.1 - 3.3e-06 27.3 0.0 9.4e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold LRR_1 PF00560.33 GAX22124.1 - 4.8e-06 26.4 7.9 4.6 8.2 0.0 7.1 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 GAX22124.1 - 0.033 14.6 15.8 0.24 11.9 1.1 5.3 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX22124.1 - 0.053 13.3 9.3 0.55 10.0 1.5 5.1 3 1 2 5 5 5 0 Leucine rich repeat PAP_fibrillin PF04755.12 GAX22126.1 - 3.8e-09 36.8 0.1 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 2 PAP_fibrillin FA_desaturase_2 PF03405.14 GAX22127.1 - 4.5e-131 436.6 0.0 5.2e-131 436.3 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 GAX22127.1 - 0.0056 17.1 0.1 0.49 10.8 0.0 2.7 3 0 0 3 3 3 1 Rubrerythrin Mito_carr PF00153.27 GAX22128.1 - 9.3e-37 124.8 5.9 9.6e-18 63.9 0.1 3.7 2 1 2 4 4 4 3 Mitochondrial carrier protein TTL PF03133.15 GAX22129.1 - 6.9e-19 68.1 0.0 2.9e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAX22129.1 - 1.3e-07 31.2 0.0 0.00078 18.8 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.11 GAX22129.1 - 0.00016 21.3 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 GAX22129.1 - 0.011 15.0 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 GAX22129.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAX22129.1 - 0.15 11.7 0.1 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Amino_oxidase PF01593.24 GAX22130.1 - 7.4e-36 124.4 0.0 9.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAX22130.1 - 1.1e-13 51.5 0.1 2.7e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX22130.1 - 1.2e-10 40.7 3.6 0.00013 20.8 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 GAX22130.1 - 1.6e-10 41.1 0.0 3.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX22130.1 - 1.7e-08 34.0 1.0 0.00035 19.8 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAX22130.1 - 2.4e-07 30.3 0.5 0.0091 15.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX22130.1 - 7.5e-07 28.8 0.2 4.5e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX22130.1 - 1.6e-06 28.2 0.2 0.018 15.0 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAX22130.1 - 2.7e-06 26.9 0.4 0.00055 19.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX22130.1 - 4.5e-05 23.9 0.4 0.44 11.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX22130.1 - 8.9e-05 21.7 1.1 0.032 13.3 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 GAX22130.1 - 0.00013 21.3 0.1 0.00024 20.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 GAX22130.1 - 0.0011 18.3 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 GAX22130.1 - 0.0041 16.0 1.3 0.047 12.5 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 GAX22130.1 - 0.029 13.5 0.2 0.06 12.4 0.2 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Peripla_BP_3 PF13377.6 GAX22130.1 - 0.11 12.8 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein-like domain TMEM52 PF14979.6 GAX22133.1 - 0.037 14.0 0.2 0.062 13.2 0.2 1.4 1 0 0 1 1 1 0 Transmembrane 52 Mito_carr PF00153.27 GAX22134.1 - 2e-16 59.7 5.2 5.7e-07 29.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Aconitase PF00330.20 GAX22135.1 - 9.6e-158 526.0 0.1 1.2e-157 525.7 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAX22135.1 - 1.7e-35 122.2 0.0 3.2e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 GAX22135.1 - 0.029 14.0 0.0 0.41 10.3 0.0 2.3 1 1 0 1 1 1 0 Aconitate hydratase 2 N-terminus UDG PF03167.19 GAX22137.1 - 4.3e-22 78.8 0.0 6.4e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily AA_kinase PF00696.28 GAX22138.1 - 8.1e-39 133.6 0.1 1e-38 133.3 0.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family SNF2_N PF00176.23 GAX22139.1 - 2e-27 95.9 0.0 8.9e-27 93.7 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 GAX22139.1 - 6e-18 65.3 0.3 2.6e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 GAX22139.1 - 8.4e-05 22.9 0.0 0.00023 21.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Shugoshin_C PF07557.11 GAX22139.1 - 0.16 11.8 0.9 0.38 10.6 0.9 1.7 1 0 0 1 1 1 0 Shugoshin C terminus zf-RING_5 PF14634.6 GAX22139.1 - 1 9.3 15.1 5.5 7.0 15.1 2.4 1 0 0 1 1 1 0 zinc-RING finger domain SWIB PF02201.18 GAX22140.1 - 9.6e-55 182.4 0.1 2.9e-27 94.3 0.0 2.4 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 GAX22140.1 - 2.2e-07 30.7 0.1 3.5e-05 23.6 0.2 3.3 3 0 0 3 3 3 1 DEK C terminal domain DUF5134 PF17197.4 GAX22142.1 - 0.17 11.8 0.0 1.1 9.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) A_deamin PF02137.18 GAX22143.1 - 1.6e-48 165.8 3.0 5.1e-48 164.2 3.0 1.8 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain eRF1_1 PF03463.15 GAX22144.1 - 7.1e-46 155.4 0.4 2e-45 154.0 0.1 1.9 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 GAX22144.1 - 1.3e-28 100.0 0.3 2.2e-28 99.2 0.3 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAX22144.1 - 1.5e-24 86.6 0.0 3.5e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 CoaE PF01121.20 GAX22145.1 - 1.5e-34 119.2 0.3 3.3e-33 114.8 0.3 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 GAX22145.1 - 0.002 18.6 0.1 0.02 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAX22145.1 - 0.0032 17.9 0.4 1.6 9.1 0.1 2.4 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX22145.1 - 0.0083 16.4 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX22145.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAX22145.1 - 0.049 12.9 0.1 0.53 9.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 GAX22145.1 - 0.11 12.2 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase PRK PF00485.18 GAX22145.1 - 0.16 11.7 0.1 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF825 PF05695.12 GAX22145.1 - 0.26 8.4 0.0 0.28 8.3 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Bestrophin PF01062.21 GAX22146.1 - 8.3e-12 45.1 0.4 1.9e-11 43.9 0.4 1.5 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF4355 PF14265.6 GAX22146.1 - 4.9 7.4 14.6 22 5.3 7.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Alpha_kinase PF02816.18 GAX22147.1 - 1.9e-30 106.4 0.4 5.2e-17 62.6 0.3 2.6 2 0 0 2 2 2 2 Alpha-kinase family VWA_2 PF13519.6 GAX22147.1 - 0.00035 21.2 0.0 0.0011 19.6 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF4258 PF14076.6 GAX22147.1 - 0.049 14.0 0.5 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Maf PF02545.14 GAX22148.1 - 3.8e-54 183.0 0.1 4.5e-54 182.8 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein Ribosomal_S5_C PF03719.15 GAX22149.1 - 4.8e-19 67.6 0.0 8.3e-19 66.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 GAX22149.1 - 3.2e-17 62.3 0.0 5.9e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Evr1_Alr PF04777.13 GAX22150.1 - 8.9e-15 55.0 0.8 8.9e-15 55.0 0.8 1.9 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 GAX22150.1 - 1.6e-14 53.7 0.7 3.4e-14 52.7 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX22150.1 - 0.0028 18.1 0.3 0.0082 16.6 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX22150.1 - 0.022 15.1 0.0 0.068 13.5 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Zn_Tnp_IS1595 PF12760.7 GAX22150.1 - 0.045 13.7 6.1 2.9 7.9 0.2 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DUF3795 PF12675.7 GAX22150.1 - 1 9.8 3.9 20 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3795) DUF616 PF04765.13 GAX22151.1 - 2e-07 30.6 0.0 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF616) PSI_PsaE PF02427.17 GAX22151.1 - 0.076 12.7 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE Glyco_transf_90 PF05686.12 GAX22152.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 Exostosin PF03016.15 GAX22152.1 - 0.038 13.2 0.0 0.14 11.4 0.0 1.9 2 1 0 2 2 2 0 Exostosin family WD40 PF00400.32 GAX22153.1 - 2.7e-30 103.9 16.3 9.3e-07 29.5 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX22153.1 - 2.4e-08 34.1 0.8 0.54 10.6 0.0 5.4 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 GAX22155.1 - 3e-49 167.8 7.2 3e-49 167.8 7.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX22155.1 - 4.9e-19 68.5 4.2 3.1e-18 65.9 4.5 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 GAX22155.1 - 1.7e-06 27.6 4.1 0.0001 21.7 0.0 2.7 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 GAX22155.1 - 9.6e-05 20.9 0.0 0.0094 14.3 0.0 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 GAX22155.1 - 0.0062 15.4 1.6 0.31 9.8 0.3 2.6 1 1 1 2 2 2 2 MFS_1 like family Folate_carrier PF01770.18 GAX22155.1 - 0.049 12.4 0.0 0.65 8.7 0.0 2.0 2 0 0 2 2 2 0 Reduced folate carrier Beta_helix PF13229.6 GAX22156.1 - 6.6e-08 32.6 1.7 0.00018 21.4 0.9 2.3 2 0 0 2 2 2 2 Right handed beta helix region DUF5123 PF17161.4 GAX22156.1 - 0.0002 22.4 3.1 0.038 15.1 0.1 3.4 4 0 0 4 4 4 2 Domain of unknown function (DUF5123) Pentapeptide_3 PF13576.6 GAX22156.1 - 0.011 15.9 3.7 9.2 6.5 0.2 4.0 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) HMG_box PF00505.19 GAX22157.1 - 4e-33 113.6 11.6 2.9e-21 75.7 0.9 2.7 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX22157.1 - 3.2e-19 69.3 14.4 6.8e-11 42.6 3.4 2.6 2 0 0 2 2 2 2 HMG-box domain Peroxin-13_N PF04088.13 GAX22157.1 - 0.23 11.7 0.7 9.7 6.5 0.1 2.3 2 1 0 2 2 2 0 Peroxin 13, N-terminal region Catalase-rel PF06628.12 GAX22157.1 - 0.49 10.6 3.1 36 4.7 0.1 3.0 2 1 1 3 3 3 0 Catalase-related immune-responsive NST1 PF13945.6 GAX22157.1 - 1.9 8.5 15.2 0.47 10.5 0.4 3.0 1 1 1 3 3 3 0 Salt tolerance down-regulator DUF3106 PF11304.8 GAX22157.1 - 3 8.4 12.5 17 5.9 5.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) DUF1289 PF06945.13 GAX22157.1 - 7.7 6.4 8.3 37 4.2 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) RRM_1 PF00076.22 GAX22158.1 - 9.4e-19 67.0 0.0 9.8e-08 31.7 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX22158.1 - 2.7e-08 33.8 0.0 0.0011 19.0 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif DNA_topoisoIV PF00521.20 GAX22159.1 - 1.1e-138 462.8 0.0 1.4e-138 462.4 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 GAX22159.1 - 1e-57 191.4 6.7 1.1e-12 47.2 0.1 6.4 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Borrelia_REV PF03978.13 GAX22159.1 - 0.00044 20.3 2.1 0.001 19.1 2.1 1.5 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein KHA PF11834.8 GAX22159.1 - 0.0064 16.6 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel HIP1_clath_bdg PF16515.5 GAX22159.1 - 0.75 10.4 7.6 2 9.1 7.6 1.7 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 GAX22159.1 - 3 6.9 6.3 5.3 6.0 6.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4815 PF16075.5 GAX22160.1 - 0.015 13.7 0.0 0.024 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) Ge1_WD40 PF16529.5 GAX22162.1 - 0.00047 19.2 0.0 0.32 9.9 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 GAX22162.1 - 0.7 10.9 11.5 4.7 8.3 0.1 6.6 9 1 0 9 9 9 0 WD domain, G-beta repeat Glyco_hydro_1 PF00232.18 GAX22163.1 - 1.9e-30 105.7 0.0 2e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 GAX22164.1 - 5.5e-84 282.2 0.0 6.1e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Aa_trans PF01490.18 GAX22165.1 - 5.7e-49 166.9 11.7 8.6e-49 166.3 11.7 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAX22165.1 - 1.6e-07 30.7 7.9 1.6e-07 30.7 7.9 3.0 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family DUF992 PF06186.11 GAX22165.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF992) 7TMR-DISM_7TM PF07695.11 GAX22165.1 - 4.2 7.2 13.3 1.2 9.0 3.3 3.1 3 0 0 3 3 3 0 7TM diverse intracellular signalling Peptidase_S9 PF00326.21 GAX22166.1 - 4.6e-20 72.0 0.1 1.4e-18 67.2 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Rotamase PF00639.21 GAX22167.1 - 0.032 15.2 0.4 0.5 11.4 0.1 2.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain Senescence PF06911.12 GAX22167.1 - 0.68 10.2 6.0 3 8.1 0.1 2.6 3 0 0 3 3 3 0 Senescence-associated protein CCB1 PF12046.8 GAX22168.1 - 1.7e-54 183.6 0.1 2.1e-54 183.4 0.1 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B DUF4131 PF13567.6 GAX22168.1 - 0.0074 15.9 1.4 2.3 7.8 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4131) Hist_deacetyl PF00850.19 GAX22169.1 - 1.2e-41 143.2 0.1 1.4e-41 143.0 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain B12-binding PF02310.19 GAX22169.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Synaptobrevin PF00957.21 GAX22170.1 - 3.2e-15 55.7 1.7 5.9e-15 54.8 1.7 1.4 1 0 0 1 1 1 1 Synaptobrevin CorA PF01544.18 GAX22170.1 - 0.069 12.4 2.3 0.058 12.7 1.0 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein 4F5 PF04419.14 GAX22171.1 - 1.7e-05 25.6 8.8 1.7e-05 25.6 8.8 2.6 1 1 1 2 2 2 1 4F5 protein family Isochorismatase PF00857.20 GAX22172.1 - 9.3e-46 156.2 0.0 1.1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family 12TM_1 PF09847.9 GAX22173.1 - 0.28 10.2 0.7 0.36 9.9 0.7 1.1 1 0 0 1 1 1 0 Membrane protein of 12 TMs Isochorismatase PF00857.20 GAX22174.1 - 5.1e-44 150.5 0.0 6.8e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF4022 PF13214.6 GAX22174.1 - 0.00023 21.3 0.5 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4022) Phage_holin_3_1 PF05106.12 GAX22175.1 - 0.01 16.3 2.3 0.03 14.8 0.2 2.6 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) MFS_MOT1 PF16983.5 GAX22175.1 - 0.094 13.1 16.6 0.88 10.0 4.7 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily CitMHS PF03600.16 GAX22176.1 - 3.1e-45 154.7 37.8 4.4e-35 121.3 13.2 2.2 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 GAX22176.1 - 4.6e-26 90.4 0.1 1.5e-09 37.5 0.0 5.9 5 1 0 5 5 5 4 TrkA-C domain Na_sulph_symp PF00939.19 GAX22176.1 - 3e-15 56.2 36.8 1.2e-08 34.5 14.1 3.1 2 1 1 3 3 3 3 Sodium:sulfate symporter transmembrane region ACT PF01842.25 GAX22176.1 - 0.0034 17.1 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain Cupin_6 PF12852.7 GAX22176.1 - 0.0052 16.5 0.2 0.19 11.4 0.2 3.0 3 0 0 3 3 3 1 Cupin EbsA PF17255.2 GAX22176.1 - 0.69 10.2 3.0 1.8 8.9 3.0 1.7 1 0 0 1 1 1 0 EbsA-like protein VHL PF01847.16 GAX22177.1 - 6.8e-07 29.1 0.3 1.3e-06 28.2 0.3 1.4 1 0 0 1 1 1 1 VHL beta domain PUB PF09409.10 GAX22177.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 PUB domain DUF1365 PF07103.11 GAX22178.1 - 7.4e-65 219.0 6.7 8.9e-65 218.7 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) TMEM154 PF15102.6 GAX22178.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family DUF4381 PF14316.6 GAX22178.1 - 0.2 11.9 0.8 0.39 11.0 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pyr_redox_2 PF07992.14 GAX22180.1 - 8.4e-45 153.2 0.0 7.6e-44 150.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX22180.1 - 3.1e-10 40.5 0.0 1.9e-06 28.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX22180.1 - 0.00028 21.0 0.0 0.0083 16.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX22180.1 - 0.016 14.3 0.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 GAX22180.1 - 0.03 13.5 0.0 4.8 6.2 0.0 2.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Mito_carr PF00153.27 GAX22181.1 - 1.9e-50 168.7 0.7 9.2e-16 57.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SUIM_assoc PF16619.5 GAX22181.1 - 0.02 14.9 0.7 0.036 14.1 0.7 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 GAX22181.1 - 0.11 11.3 3.9 0.19 10.5 3.9 1.5 1 0 0 1 1 1 0 Androgen receptor Peptidase_C11 PF03415.14 GAX22182.1 - 1.9e-25 90.0 0.0 2.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Clostripain family Period_C PF12114.8 GAX22182.1 - 0.25 10.9 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF4461 PF14688.6 GAX22183.1 - 5.8e-24 85.5 0.9 7.9e-24 85.0 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) Kindlin_2_N PF18124.1 GAX22183.1 - 0.0037 17.4 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 1 Kindlin-2 N-terminal domain ArsC PF03960.15 GAX22183.1 - 0.021 14.8 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 ArsC family Rhodanese_C PF12368.8 GAX22185.1 - 6.4e-14 52.1 4.0 1.4e-13 51.0 4.0 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 GAX22185.1 - 1.8e-09 37.8 0.0 5.3e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GAX22185.1 - 0.00052 20.5 1.5 0.001 19.5 0.0 2.4 2 1 0 2 2 2 1 Rhodanese-like domain FYVE PF01363.21 GAX22185.1 - 0.0015 18.6 6.3 0.0039 17.3 6.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger RRM_1 PF00076.22 GAX22185.1 - 0.1 12.4 0.2 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 GAX22186.1 - 4.6e-63 213.3 0.0 6.6e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAX22186.1 - 1.1e-07 32.1 0.0 3.4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAX22186.1 - 7.3e-05 23.7 1.0 0.0024 18.8 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 GAX22186.1 - 0.022 14.5 12.4 2.9 7.7 1.9 4.9 4 0 0 4 4 4 0 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAX22186.1 - 0.55 10.0 10.3 1.2 8.9 0.4 4.7 5 0 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase AAA_26 PF13500.6 GAX22187.1 - 1.5e-39 135.9 0.0 2.3e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX22187.1 - 3.6e-06 27.1 0.0 8.8e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 GAX22187.1 - 0.014 15.1 0.0 0.17 11.7 0.0 2.4 1 1 0 1 1 1 0 DRTGG domain Pkinase PF00069.25 GAX22188.1 - 1.6e-10 40.8 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22188.1 - 1.5e-05 24.4 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase E1-E2_ATPase PF00122.20 GAX22189.1 - 2.1e-48 164.2 3.3 2.1e-48 164.2 3.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX22189.1 - 2.2e-41 141.6 1.4 2.2e-41 141.6 1.4 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAX22189.1 - 2.3e-19 69.3 0.0 4.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAX22189.1 - 3.3e-19 70.0 1.2 7.6e-18 65.6 1.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX22189.1 - 9.3e-17 60.5 0.1 2.4e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX22189.1 - 1.7e-05 24.7 0.9 7e-05 22.7 1.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX22189.1 - 0.064 13.6 0.0 0.21 12.0 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HRG PF16954.5 GAX22189.1 - 5.3 7.5 7.8 4.1 7.9 0.3 2.9 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF2407_C PF13373.6 GAX22191.1 - 1.1e-20 74.3 0.2 1.7e-20 73.6 0.2 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 GAX22191.1 - 8.2e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GAX22191.1 - 1.4e-05 25.6 0.1 2.4e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Globin PF00042.22 GAX22192.1 - 5.2e-14 52.7 0.0 8.6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Globin Nudix_hydro PF18290.1 GAX22193.1 - 6.8e-21 74.1 0.3 1.3e-20 73.2 0.3 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 GAX22193.1 - 4.5e-18 65.6 0.0 7.4e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain GTP_EFTU PF00009.27 GAX22195.1 - 6.7e-33 113.9 0.0 8.8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAX22195.1 - 3.1e-18 66.1 0.0 1e-17 64.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 GAX22195.1 - 0.0075 16.3 0.0 0.031 14.3 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 GAX22195.1 - 0.07 12.7 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PCO_ADO PF07847.12 GAX22196.1 - 0.03 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 PCO_ADO tRNA_bind_3 PF17176.4 GAX22197.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 tRNA-binding domain UQ_con PF00179.26 GAX22198.1 - 1.7e-12 47.2 0.0 5.8e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX22198.1 - 0.009 16.3 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 GAX22198.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B Adeno_E3 PF06040.11 GAX22199.1 - 0.042 14.0 0.2 0.12 12.5 0.2 1.8 1 0 0 1 1 1 0 Adenovirus E3 protein UPF0060 PF02694.15 GAX22200.1 - 1.3e-36 125.0 7.3 1.6e-36 124.8 7.3 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family VKG_Carbox PF05090.14 GAX22200.1 - 0.037 12.9 0.6 0.046 12.5 0.6 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase EamA PF00892.20 GAX22200.1 - 0.051 13.7 4.6 0.1 12.7 4.6 1.5 1 1 0 1 1 1 0 EamA-like transporter family DUF202 PF02656.15 GAX22200.1 - 0.067 13.6 3.9 1 9.8 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) MerC PF03203.14 GAX22200.1 - 2.8 8.4 7.1 5.9 7.4 7.1 1.7 1 1 0 1 1 1 0 MerC mercury resistance protein Chromate_transp PF02417.15 GAX22201.1 - 5.6e-65 218.3 34.3 2.5e-39 134.9 15.9 2.5 3 0 0 3 3 3 2 Chromate transporter DUF285 PF03382.14 GAX22202.1 - 2.7e-29 101.4 3.9 3.6e-27 94.5 3.2 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 DUF285 PF03382.14 GAX22203.1 - 1.1e-40 138.2 12.6 8.3e-24 83.7 1.8 2.8 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Glyco_tranf_2_2 PF10111.9 GAX22203.1 - 0.018 14.5 0.2 0.027 14.0 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Peptidase_M22 PF00814.25 GAX22204.1 - 7e-88 294.8 0.2 8.8e-88 294.5 0.2 1.0 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.20 GAX22204.1 - 0.17 11.4 0.2 1.1 8.7 0.2 2.3 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DnaJ PF00226.31 GAX22205.1 - 5.4e-23 80.9 0.2 1.2e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1299 PF06975.11 GAX22205.1 - 3.1 7.9 5.0 5.3 7.2 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) DnaJ PF00226.31 GAX22206.1 - 2.1e-11 43.8 0.7 7.9e-11 41.9 0.7 2.0 1 1 0 1 1 1 1 DnaJ domain EcKinase PF02958.20 GAX22206.1 - 0.026 13.9 1.1 0.04 13.2 1.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Snf7 PF03357.21 GAX22208.1 - 5.9e-15 55.3 11.3 1.1e-14 54.5 11.3 1.3 1 0 0 1 1 1 1 Snf7 VSG_B PF13206.6 GAX22208.1 - 0.066 12.5 1.5 0.099 11.9 1.5 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Imm5 PF14423.6 GAX22208.1 - 2.9 8.1 6.3 0.53 10.5 1.8 2.0 2 1 0 2 2 2 0 Immunity protein Imm5 ATP-synt_C PF00137.21 GAX22209.1 - 8e-33 112.6 25.6 1.3e-17 63.9 13.2 3.0 2 1 0 2 2 2 2 ATP synthase subunit C DUF4577 PF15145.6 GAX22209.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) ATP-synt_C PF00137.21 GAX22210.1 - 8.7e-37 125.3 19.3 1.4e-23 83.0 4.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF5522 PF17653.1 GAX22210.1 - 0.095 12.7 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) MBOAT_2 PF13813.6 GAX22211.1 - 5.4e-10 39.4 0.5 5.4e-10 39.4 0.5 2.2 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Cytochrom_B_C PF00032.17 GAX22211.1 - 0.17 12.2 0.3 0.17 12.2 0.3 2.9 3 1 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD RNA_pol_Rpb8 PF03870.15 GAX22212.1 - 1.8e-42 144.8 0.0 2e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 GAX22212.1 - 0.0015 18.6 0.0 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase, subunit G DUF16 PF01519.16 GAX22213.1 - 0.0049 17.3 3.9 0.01 16.3 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 ADIP PF11559.8 GAX22213.1 - 0.027 14.5 4.8 0.058 13.5 4.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YlqD PF11068.8 GAX22213.1 - 0.047 14.1 4.4 0.2 12.1 3.1 2.4 3 0 0 3 3 3 0 YlqD protein DUF4763 PF15960.5 GAX22213.1 - 0.062 12.6 4.7 0.12 11.6 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) FliD_C PF07195.12 GAX22213.1 - 0.11 11.9 0.8 0.21 11.0 0.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus GrpE PF01025.19 GAX22213.1 - 0.24 11.1 4.8 1.6 8.4 3.7 2.1 2 0 0 2 2 2 0 GrpE SlyX PF04102.12 GAX22213.1 - 0.71 10.5 7.0 6 7.6 7.0 2.4 1 1 0 1 1 1 0 SlyX Sec2p PF06428.11 GAX22213.1 - 1.7 8.6 6.5 4.4 7.3 6.5 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cortex-I_coil PF09304.10 GAX22213.1 - 3.1 8.1 7.9 1.9 8.8 2.6 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil XPG_N PF00752.17 GAX22215.1 - 2.1e-31 108.4 0.1 7.2e-31 106.7 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 GAX22215.1 - 6.1e-27 93.8 0.2 1.3e-26 92.8 0.2 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 GAX22215.1 - 5e-07 30.2 0.1 1.5e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GAX22215.1 - 0.019 15.6 0.0 0.051 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Fe_dep_repr_C PF02742.15 GAX22215.1 - 0.026 14.6 0.1 8.4 6.6 0.0 3.0 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain Glycos_transf_3 PF00591.21 GAX22216.1 - 3e-29 102.4 0.0 6.2e-29 101.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 GAX22216.1 - 5.7e-17 61.3 0.1 1.6e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain PYNP_C PF07831.13 GAX22216.1 - 1.5e-16 59.8 0.0 3.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain SWIM PF04434.17 GAX22217.1 - 0.0007 19.2 2.1 0.0017 18.0 2.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-C3HC4_3 PF13920.6 GAX22218.1 - 5.8e-05 22.9 11.6 0.0001 22.1 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX22218.1 - 0.0018 18.5 13.0 0.0034 17.7 13.0 1.5 1 0 0 1 1 1 1 Ring finger domain UIM PF02809.20 GAX22218.1 - 0.013 15.3 2.8 0.013 15.3 2.8 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif zf-C3HC4_2 PF13923.6 GAX22218.1 - 0.037 13.9 12.6 0.078 12.8 12.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX22218.1 - 0.16 11.9 12.8 0.28 11.1 12.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3070 PF11270.8 GAX22218.1 - 0.6 10.4 0.0 0.6 10.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3070) DnaJ PF00226.31 GAX22219.1 - 9.5e-25 86.5 5.5 2.2e-24 85.4 5.5 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_6 PF13848.6 GAX22219.1 - 2.7e-06 27.4 0.1 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain zf-LITAF-like PF10601.9 GAX22220.1 - 8.9e-05 22.7 1.3 0.00014 22.0 1.3 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DSBA PF01323.20 GAX22221.1 - 3.3e-05 23.8 1.2 0.00028 20.7 1.2 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 GAX22221.1 - 0.0013 19.0 0.5 0.0059 16.8 0.5 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 GAX22221.1 - 0.023 14.7 0.0 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain NDUF_B7 PF05676.13 GAX22221.1 - 0.24 11.1 3.7 1.7 8.5 0.0 2.5 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Rotamase PF00639.21 GAX22222.1 - 1.6e-18 67.4 0.0 2.9e-18 66.6 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX22222.1 - 2.1e-16 60.5 0.0 3.4e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAX22222.1 - 0.0027 18.6 0.0 0.0033 18.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF1376 PF07120.11 GAX22222.1 - 0.024 15.0 0.0 0.034 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) Cupin_8 PF13621.6 GAX22223.1 - 7.6e-18 65.1 0.7 1.1e-17 64.7 0.7 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX22223.1 - 0.00025 20.6 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 GAX22223.1 - 0.0081 16.6 0.1 0.15 12.5 0.0 2.8 1 1 1 2 2 2 1 JmjC domain, hydroxylase CitMHS PF03600.16 GAX22224.1 - 2.4e-54 184.6 0.1 5.2e-47 160.5 0.0 2.3 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 GAX22224.1 - 2.5e-28 97.7 0.0 3e-10 39.8 0.0 6.3 5 1 0 5 5 5 4 TrkA-C domain Na_sulph_symp PF00939.19 GAX22224.1 - 4.1e-10 39.3 40.9 6.9e-07 28.7 17.3 3.1 2 1 1 3 3 3 3 Sodium:sulfate symporter transmembrane region DctM PF06808.12 GAX22224.1 - 0.00029 19.8 11.3 0.00029 19.8 11.3 2.4 2 0 0 2 2 2 2 Tripartite ATP-independent periplasmic transporter, DctM component ACT PF01842.25 GAX22224.1 - 0.0029 17.3 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 ACT domain Cupin_6 PF12852.7 GAX22224.1 - 0.039 13.7 0.2 0.14 11.8 0.2 1.9 2 0 0 2 2 2 0 Cupin CitMHS PF03600.16 GAX22225.1 - 2.5e-42 145.1 42.6 2e-34 119.2 14.8 2.5 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 GAX22225.1 - 1.4e-26 92.1 0.7 6.2e-10 38.8 0.0 6.2 6 1 0 6 6 6 4 TrkA-C domain ACT PF01842.25 GAX22225.1 - 0.033 14.0 0.0 0.094 12.5 0.0 1.8 1 0 0 1 1 1 0 ACT domain vATP-synt_E PF01991.18 GAX22226.1 - 5e-48 163.2 6.4 6.1e-48 162.9 6.4 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phage_holin_T PF11031.8 GAX22226.1 - 0.036 13.6 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage T holin Methyltr_RsmB-F PF01189.17 GAX22228.1 - 2.6e-20 72.9 0.0 9.9e-20 71.0 0.0 2.0 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Sec34 PF04136.15 GAX22229.1 - 2.9e-09 37.0 5.3 3.2e-09 36.8 1.8 2.9 2 1 0 2 2 2 1 Sec34-like family MTHFR PF02219.17 GAX22229.1 - 0.012 15.0 0.9 0.012 15.0 0.9 1.7 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase Pil1 PF13805.6 GAX22229.1 - 0.56 9.7 6.3 0.073 12.6 0.5 2.5 3 0 0 3 3 3 0 Eisosome component PIL1 ALIX_LYPXL_bnd PF13949.6 GAX22230.1 - 1e-32 113.6 18.1 1e-32 113.6 18.1 3.3 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.18 GAX22230.1 - 1.2e-17 63.8 0.1 6e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 BRO1-like domain UBA PF00627.31 GAX22230.1 - 0.0002 21.2 0.2 0.00059 19.7 0.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 GAX22230.1 - 0.0081 15.8 0.7 0.043 13.5 0.0 2.4 2 0 0 2 2 2 1 CUE domain EAP30 PF04157.16 GAX22230.1 - 2.3 7.4 7.2 0.13 11.5 0.7 2.2 2 1 0 2 2 2 0 EAP30/Vps36 family DUF5082 PF16888.5 GAX22230.1 - 5 7.4 7.9 12 6.2 2.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) UreD PF01774.17 GAX22231.1 - 7.5e-44 150.2 0.2 1.6e-43 149.1 0.2 1.6 1 0 0 1 1 1 1 UreD urease accessory protein UreF PF01730.16 GAX22231.1 - 3.4e-14 53.6 0.3 3.4e-14 53.6 0.3 2.1 2 0 0 2 2 2 1 UreF CMAS PF02353.20 GAX22232.1 - 5.2e-35 121.1 0.3 7.6e-35 120.5 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 GAX22232.1 - 6.4e-11 42.9 0.0 1e-10 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX22232.1 - 2e-09 37.2 0.0 3.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX22232.1 - 2.2e-09 37.9 0.0 5.1e-09 36.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX22232.1 - 2.6e-09 37.1 0.0 4.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22232.1 - 1.5e-08 35.1 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22232.1 - 4.9e-08 33.0 0.0 8.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAX22232.1 - 3.8e-05 23.2 0.1 0.00016 21.2 0.1 2.0 1 1 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 GAX22232.1 - 0.00035 20.4 0.0 0.00064 19.5 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA_U5-meth_tr PF05958.11 GAX22232.1 - 0.0036 16.4 0.0 0.0064 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase FtsJ PF01728.19 GAX22232.1 - 0.0078 16.3 0.1 0.019 15.0 0.1 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase DOT1 PF08123.13 GAX22232.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.14 GAX22232.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB GidB PF02527.15 GAX22232.1 - 0.021 14.1 0.0 0.068 12.5 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 GAX22232.1 - 0.046 13.7 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 GAX22232.1 - 0.056 12.7 0.0 0.18 11.1 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase domain tRNA-synt_2c PF01411.19 GAX22234.1 - 2.3e-188 627.2 0.0 3.2e-188 626.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAX22234.1 - 2.2e-15 56.4 1.3 5.6e-15 55.2 1.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAX22234.1 - 2.3e-12 47.5 2.9 7.4e-12 45.9 2.9 2.0 1 0 0 1 1 1 1 DHHA1 domain DUF4866 PF16160.5 GAX22235.1 - 0.098 12.0 0.2 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) CMAS PF02353.20 GAX22236.1 - 7.1e-72 242.0 0.0 9.8e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Amino_oxidase PF01593.24 GAX22236.1 - 2.4e-17 63.4 0.0 7.4e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX22236.1 - 7.8e-15 54.9 0.0 2.1e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_25 PF13649.6 GAX22236.1 - 6.5e-10 39.6 0.1 2.8e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22236.1 - 8.3e-09 36.0 0.0 2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 GAX22236.1 - 3.7e-07 30.1 0.1 7.5e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Methyltransf_31 PF13847.6 GAX22236.1 - 2.1e-06 27.6 0.0 4.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22236.1 - 8.4e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_9 PF13454.6 GAX22236.1 - 2.9e-05 24.1 0.5 0.0015 18.5 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAX22236.1 - 5.2e-05 22.6 0.0 9.6e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAX22236.1 - 0.001 18.4 0.1 0.0022 17.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DOT1 PF08123.13 GAX22236.1 - 0.004 16.7 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 FAD_binding_2 PF00890.24 GAX22236.1 - 0.0074 15.4 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain MTS PF05175.14 GAX22236.1 - 0.011 15.3 0.0 0.059 12.9 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase small domain FtsJ PF01728.19 GAX22236.1 - 0.03 14.4 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase HI0933_like PF03486.14 GAX22236.1 - 0.036 12.8 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 GAX22236.1 - 0.096 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ACP_syn_III_C PF08541.10 GAX22236.1 - 0.18 12.0 0.0 4.6 7.5 0.0 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal GIDA PF01134.22 GAX22236.1 - 0.26 10.3 0.1 0.45 9.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribosomal_L28 PF00830.19 GAX22238.1 - 0.14 12.4 0.7 0.98 9.7 0.0 2.5 3 0 0 3 3 3 0 Ribosomal L28 family DUF21 PF01595.20 GAX22239.1 - 7.3e-22 77.9 0.2 1.7e-21 76.7 0.2 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 GAX22239.1 - 1e-16 60.7 0.9 4.5e-16 58.6 0.0 2.6 3 0 0 3 3 3 1 Transporter associated domain CBS PF00571.28 GAX22239.1 - 8.6e-16 58.1 3.7 1.1e-07 32.2 1.1 2.8 2 0 0 2 2 2 2 CBS domain DUF4079 PF13301.6 GAX22240.1 - 9.8e-47 158.7 0.3 1.6e-46 157.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Lzipper-MIP1 PF14389.6 GAX22240.1 - 0.11 12.8 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Ank_2 PF12796.7 GAX22241.1 - 6.8e-12 45.8 0.0 4.4e-06 27.2 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX22241.1 - 3.5e-06 27.5 0.1 0.00019 21.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX22241.1 - 0.00039 20.6 0.3 0.047 14.3 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 GAX22241.1 - 0.0014 18.9 0.1 0.0067 16.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX22241.1 - 0.0038 17.6 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Peptidase_M6 PF05547.11 GAX22242.1 - 2.1e-05 23.1 0.2 4.2e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Glyco_tran_WecB PF03808.13 GAX22242.1 - 0.21 11.6 0.0 0.48 10.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family HSP70 PF00012.20 GAX22243.1 - 7.5e-46 156.5 0.0 1.2e-42 146.0 0.0 3.4 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GAX22243.1 - 3.4e-11 42.6 0.5 2.2e-06 26.7 0.0 3.3 3 1 0 3 3 3 2 MreB/Mbl protein MutL PF13941.6 GAX22243.1 - 0.12 11.0 0.1 0.2 10.2 0.1 1.3 1 0 0 1 1 1 0 MutL protein SOSSC PF15925.5 GAX22244.1 - 0.082 14.2 0.0 0.12 13.7 0.0 1.2 1 0 0 1 1 1 0 SOSS complex subunit C GRDP-like PF07173.12 GAX22245.1 - 2.2e-33 115.9 1.1 1.8e-23 83.8 0.2 3.2 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like Abhydrolase_1 PF00561.20 GAX22246.1 - 2.5e-14 53.6 0.2 4.3e-13 49.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX22246.1 - 1.6e-10 41.9 0.9 2.2e-10 41.5 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX22246.1 - 9.3e-10 38.2 0.0 1.7e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAX22246.1 - 0.00018 21.7 0.1 0.00035 20.8 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 GAX22246.1 - 0.0022 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 GAX22246.1 - 0.0025 17.2 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 GAX22246.1 - 0.051 13.1 0.0 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 GAX22246.1 - 0.13 12.1 0.0 2.2 8.0 0.0 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 GAX22246.1 - 0.19 10.2 0.0 0.33 9.4 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ank_4 PF13637.6 GAX22247.1 - 9.6e-09 35.6 0.1 0.00015 22.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX22247.1 - 2.9e-08 33.8 0.1 2.1e-05 24.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX22247.1 - 7e-08 33.0 0.1 1.6e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX22247.1 - 1.7e-06 27.9 0.1 0.023 15.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAX22247.1 - 0.0034 17.8 0.1 2.2 8.9 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat AAA_12 PF13087.6 GAX22248.1 - 1.9e-54 184.4 0.0 5.6e-54 182.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAX22248.1 - 2.5e-39 135.6 2.6 3.8e-25 89.1 0.8 4.3 4 1 1 5 5 5 2 AAA domain AAA_19 PF13245.6 GAX22248.1 - 2.4e-10 40.9 0.2 5.8e-08 33.2 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAX22248.1 - 5.2e-09 36.1 3.3 7e-09 35.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 GAX22248.1 - 0.00075 19.3 0.0 0.44 10.2 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 GAX22248.1 - 0.0013 19.2 0.0 0.0079 16.6 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 GAX22248.1 - 0.0028 16.9 4.2 0.016 14.5 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 GAX22248.1 - 0.0037 16.5 0.0 0.0087 15.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 GAX22248.1 - 0.0054 16.7 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 GAX22248.1 - 0.0092 16.4 0.0 0.029 14.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAX22248.1 - 0.016 14.8 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 GAX22248.1 - 0.023 14.2 0.0 0.085 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 GAX22248.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC Helicase_RecD PF05127.14 GAX22248.1 - 0.14 12.0 4.0 1.1 9.1 0.0 3.0 2 1 1 3 3 3 0 Helicase Ank_5 PF13857.6 GAX22250.1 - 1.4e-09 38.1 0.2 8.9e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX22250.1 - 1.1e-07 32.3 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX22250.1 - 8.5e-06 25.7 0.0 0.0049 17.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 GAX22250.1 - 9.3e-05 22.9 0.1 0.00029 21.3 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX22250.1 - 0.012 16.0 0.1 0.42 11.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Cwf_Cwc_15 PF04889.12 GAX22250.1 - 0.41 10.4 6.5 0.56 9.9 6.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tom22 PF04281.13 GAX22250.1 - 0.95 9.3 4.6 1.6 8.5 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Astro_capsid_p PF12226.8 GAX22250.1 - 1.2 8.2 10.3 2.2 7.4 10.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Aminotran_3 PF00202.21 GAX22251.1 - 2.8e-109 365.5 0.1 3.4e-109 365.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 GAX22251.1 - 0.077 11.9 0.2 1.1 8.2 0.2 2.5 2 1 1 3 3 3 0 Aminotransferase class-V Peptidase_S8 PF00082.22 GAX22254.1 - 3.2e-39 135.0 10.0 4.9e-39 134.4 10.0 1.3 1 0 0 1 1 1 1 Subtilase family Toxin_12 PF07740.12 GAX22254.1 - 0.23 12.2 10.6 0.47 11.2 10.6 1.6 1 0 0 1 1 1 0 Ion channel inhibitory toxin Mem_trans PF03547.18 GAX22255.1 - 2.7e-20 72.1 16.6 3.7e-11 42.0 9.0 2.1 1 1 0 2 2 2 2 Membrane transport protein Rad51 PF08423.11 GAX22257.1 - 2.9e-42 144.7 0.0 5.4e-42 143.8 0.0 1.4 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAX22257.1 - 1.6e-09 37.6 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAX22257.1 - 6.3e-06 25.7 0.1 3e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 GAX22257.1 - 0.012 15.0 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RecA PF00154.21 GAX22257.1 - 0.016 14.7 0.1 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein Vps8 PF12816.7 GAX22258.1 - 1.6e-46 158.3 2.8 1.8e-46 158.2 1.0 2.1 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 GAX22258.1 - 2.1e-06 27.7 1.8 1.5e-05 24.9 0.6 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS Sulfotransfer_2 PF03567.14 GAX22259.1 - 9.7e-10 38.8 0.1 1.5e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family RsbU_N PF08673.10 GAX22260.1 - 0.0026 17.8 0.4 0.35 11.0 0.0 2.7 1 1 1 2 2 2 1 Phosphoserine phosphatase RsbU, N-terminal domain TPR_16 PF13432.6 GAX22260.1 - 0.0084 16.7 10.0 0.029 15.0 1.7 4.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX22260.1 - 0.039 14.2 21.0 0.15 12.4 2.1 6.4 7 1 1 8 8 8 0 Tetratricopeptide repeat Inv-AAD PF18785.1 GAX22260.1 - 0.068 13.0 0.2 0.48 10.3 0.0 2.3 3 0 0 3 3 3 0 Invertebrate-AID/APOBEC-deaminase Bacillus_PapR PF05968.11 GAX22260.1 - 0.15 12.0 0.1 0.4 10.6 0.1 1.7 1 0 0 1 1 1 0 Bacillus PapR protein TPR_4 PF07721.14 GAX22260.1 - 0.2 12.4 2.6 62 4.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat YlbD_coat PF14071.6 GAX22260.1 - 0.43 10.8 2.7 0.57 10.5 0.7 2.1 2 0 0 2 2 2 0 Putative coat protein TPR_1 PF00515.28 GAX22260.1 - 0.78 9.7 7.3 17 5.4 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX22260.1 - 3 8.2 15.0 4.8 7.6 0.5 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat NOG1 PF06858.14 GAX22261.1 - 1.3e-17 63.3 0.0 3.2e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GAX22261.1 - 1.9e-15 56.9 0.0 5.2e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1_N PF17835.1 GAX22261.1 - 3.7e-10 40.0 0.3 6.3e-10 39.2 0.3 1.4 1 0 0 1 1 1 1 NOG1 N-terminal helical domain FeoB_N PF02421.18 GAX22261.1 - 8.1e-06 25.4 0.1 2.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAX22261.1 - 0.00095 19.6 0.1 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF4733 PF15878.5 GAX22261.1 - 0.0018 18.7 0.2 0.16 12.4 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4733) AAA_18 PF13238.6 GAX22261.1 - 0.0055 17.2 0.0 0.53 10.8 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_15 PF13175.6 GAX22261.1 - 0.01 15.6 0.1 0.094 12.4 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain TniB PF05621.11 GAX22261.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 GAX22261.1 - 0.061 13.4 0.2 7.5 6.6 0.1 2.6 1 1 0 2 2 2 0 Dynamin family AAA_5 PF07728.14 GAX22261.1 - 0.094 12.7 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 GAX22261.1 - 0.18 12.0 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase COPIIcoated_ERV PF07970.12 GAX22262.1 - 1.5e-22 80.5 0.2 3.7e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX22262.1 - 7.6e-22 77.5 1.0 1.6e-21 76.5 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 GAX22262.1 - 8.3e-20 70.7 0.1 2.3e-11 43.6 0.2 2.5 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAX22262.1 - 0.00049 20.5 0.1 0.0015 19.0 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX22262.1 - 0.0012 19.2 0.5 0.051 13.9 0.0 3.2 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GAX22262.1 - 0.0041 17.3 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX22262.1 - 0.065 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin WD40 PF00400.32 GAX22263.1 - 0.0035 18.2 0.5 7.5 7.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat CAF1 PF04857.20 GAX22264.1 - 1.2e-18 67.4 1.2 6.5e-10 38.7 0.0 2.7 2 1 0 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 GAX22264.1 - 0.11 12.1 0.0 15 5.3 0.0 2.4 2 1 0 2 2 2 0 3'-5' exonuclease Glyco_transf_92 PF01697.27 GAX22267.1 - 8.9e-19 68.1 0.2 1.4e-18 67.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GAX22267.1 - 9e-09 35.7 0.0 2.4e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Rft-1 PF04506.13 GAX22268.1 - 4.6e-90 302.8 11.8 6.9e-90 302.2 11.8 1.1 1 0 0 1 1 1 1 Rft protein TAXi_N PF14543.6 GAX22269.1 - 6.1e-13 49.4 1.0 1.5e-12 48.1 1.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX22269.1 - 2.7e-11 43.5 0.6 0.00031 20.3 0.0 3.2 2 2 1 3 3 3 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX22269.1 - 0.0011 18.8 0.2 0.095 12.5 0.0 2.9 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Str_synth PF03088.16 GAX22270.1 - 4.9e-13 49.0 0.0 1.1e-12 47.8 0.0 1.6 1 1 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 GAX22270.1 - 0.0099 15.5 0.0 1.3 8.6 0.0 2.5 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 GAX22270.1 - 0.081 13.1 0.0 5.9 7.2 0.0 2.8 3 0 0 3 3 3 0 Arylesterase RHINO PF15319.6 GAX22272.1 - 0.013 15.6 2.6 0.028 14.5 2.6 1.6 1 1 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Nitroreductase PF00881.24 GAX22273.1 - 3.7e-11 43.4 0.2 3.7e-11 43.4 0.2 1.7 2 1 0 2 2 2 1 Nitroreductase family Inhibitor_Mig-6 PF11555.8 GAX22273.1 - 0.12 12.5 4.2 0.14 12.3 2.6 2.0 1 1 1 2 2 2 0 EGFR receptor inhibitor Mig-6 IU_nuc_hydro PF01156.19 GAX22275.1 - 2.3e-28 99.6 0.0 2.9e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Dam PF05869.11 GAX22275.1 - 0.071 12.7 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Bul1_C PF04426.12 GAX22276.1 - 6.5 6.1 10.5 0.04 13.3 1.2 2.0 2 0 0 2 2 2 0 Bul1 C terminus SprT-like PF10263.9 GAX22277.1 - 1.5e-23 82.8 0.0 3.1e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 GAX22277.1 - 8.2e-08 32.0 4.3 1.9e-07 30.9 4.3 1.7 1 0 0 1 1 1 1 SprT-like zinc ribbon domain YABBY PF04690.13 GAX22277.1 - 0.018 15.6 0.0 0.018 15.6 0.0 2.8 2 1 0 2 2 2 0 YABBY protein HMG_box_2 PF09011.10 GAX22277.1 - 0.091 13.4 0.5 0.091 13.4 0.5 2.0 2 0 0 2 2 2 0 HMG-box domain HMG_box PF00505.19 GAX22277.1 - 0.29 11.6 1.9 0.32 11.4 0.2 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box SdpI PF13630.6 GAX22278.1 - 0.022 14.9 4.3 1.3 9.2 1.0 2.6 3 0 0 3 3 3 0 SdpI/YhfL protein family MARVEL PF01284.23 GAX22278.1 - 0.027 14.5 7.4 0.063 13.3 7.4 1.7 1 1 0 1 1 1 0 Membrane-associating domain DUF4064 PF13273.6 GAX22279.1 - 0.029 14.6 0.4 0.99 9.7 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) COPI_assoc PF08507.10 GAX22279.1 - 0.037 14.1 0.5 0.98 9.5 0.9 2.2 2 0 0 2 2 2 0 COPI associated protein Aldo_ket_red PF00248.21 GAX22280.1 - 1.5e-35 122.9 0.0 1.9e-34 119.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Transglut_core PF01841.19 GAX22282.1 - 2.3e-12 47.4 0.1 6.4e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Ank_2 PF12796.7 GAX22283.1 - 1.2e-30 105.9 0.6 3.8e-09 37.0 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX22283.1 - 1.6e-25 89.1 4.6 3.3e-08 33.9 0.0 5.4 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX22283.1 - 2.9e-25 88.0 0.1 5.8e-07 29.7 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX22283.1 - 6.1e-20 69.2 2.3 2.8e-06 27.2 0.1 5.5 5 0 0 5 5 4 3 Ankyrin repeat Ank PF00023.30 GAX22283.1 - 1.7e-13 50.3 5.3 8.3e-05 22.9 0.1 5.3 7 0 0 7 7 5 3 Ankyrin repeat Use1 PF09753.9 GAX22283.1 - 3.8e-08 33.4 2.4 6.4e-08 32.6 2.4 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 Fib_alpha PF08702.10 GAX22283.1 - 0.00031 20.9 5.2 0.00079 19.6 5.2 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Apolipoprotein PF01442.18 GAX22283.1 - 0.026 14.4 10.0 1.5 8.7 5.8 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 GAX22283.1 - 0.029 12.4 1.5 0.048 11.6 1.5 1.3 1 0 0 1 1 1 0 Prominin Mce4_CUP1 PF11887.8 GAX22283.1 - 0.033 13.6 0.3 0.065 12.7 0.3 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Yuri_gagarin PF15934.5 GAX22283.1 - 0.04 13.8 2.1 0.081 12.8 2.1 1.4 1 0 0 1 1 1 0 Yuri gagarin CHAD PF05235.14 GAX22283.1 - 0.055 13.4 3.6 0.19 11.7 3.6 2.0 1 1 0 1 1 1 0 CHAD domain LMBR1 PF04791.16 GAX22283.1 - 0.12 11.3 0.3 0.17 10.7 0.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 GAX22283.1 - 0.14 12.8 2.5 0.35 11.5 0.6 2.3 2 0 0 2 2 2 0 Initiation control protein YabA AI-2E_transport PF01594.16 GAX22283.1 - 0.26 10.4 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 AI-2E family transporter HBS1_N PF08938.10 GAX22283.1 - 0.53 10.6 3.1 0.79 10.1 1.2 2.3 2 1 0 2 2 1 0 HBS1 N-terminus DUF4446 PF14584.6 GAX22283.1 - 1.2 9.1 3.5 2.5 8.1 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF1664 PF07889.12 GAX22283.1 - 1.2 9.2 7.3 0.67 10.0 5.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 GAX22283.1 - 2.2 8.1 10.3 0.35 10.7 4.4 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 NPV_P10 PF05531.12 GAX22283.1 - 2.5 8.6 6.5 12 6.5 6.5 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.6 GAX22283.1 - 9.9 6.5 8.7 36 4.7 4.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Sec5 PF15469.6 GAX22286.1 - 8.8e-16 58.3 0.1 3.5e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 GAX22286.1 - 0.00016 20.5 0.6 0.00039 19.2 0.6 1.6 1 0 0 1 1 1 1 Dor1-like family Zw10 PF06248.13 GAX22286.1 - 0.48 8.9 4.6 0.072 11.6 0.3 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 HAD_2 PF13419.6 GAX22287.1 - 4.5e-20 72.5 0.0 1.4e-19 70.9 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX22287.1 - 5.6e-12 46.4 0.0 8.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX22287.1 - 1.7e-06 28.0 0.1 3.5e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 GAX22287.1 - 0.00034 20.4 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAX22287.1 - 0.02 15.3 0.0 0.055 13.9 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Myosin_head PF00063.21 GAX22288.1 - 6.1e-205 682.4 0.0 9e-183 609.1 0.0 2.5 3 0 0 3 3 3 2 Myosin head (motor domain) Ank_2 PF12796.7 GAX22288.1 - 6.4e-13 49.1 4.5 0.00042 20.9 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 GAX22288.1 - 6.1e-12 45.5 0.0 4.2e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 GAX22288.1 - 2.3e-11 43.7 7.9 0.016 15.5 0.3 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX22288.1 - 2.5e-06 27.9 1.3 0.00031 21.3 0.0 4.7 4 2 1 5 5 5 2 Ankyrin repeats (many copies) IQ PF00612.27 GAX22288.1 - 0.00036 20.1 24.0 0.086 12.7 0.6 5.7 6 0 0 6 6 6 3 IQ calmodulin-binding motif ATPase PF06745.13 GAX22288.1 - 0.0056 16.0 1.5 0.083 12.2 0.0 3.0 4 0 0 4 4 4 1 KaiC AAA_16 PF13191.6 GAX22288.1 - 0.041 14.3 1.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Ank_3 PF13606.6 GAX22288.1 - 0.09 13.4 10.0 19 6.2 0.0 6.7 7 0 0 7 7 7 0 Ankyrin repeat AAA_22 PF13401.6 GAX22288.1 - 0.11 12.8 0.6 1 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ank PF00023.30 GAX22288.1 - 0.26 11.8 2.6 28 5.4 0.1 4.3 3 1 0 3 3 3 0 Ankyrin repeat ABC2_membrane PF01061.24 GAX22290.1 - 1.2e-39 135.9 16.3 1.2e-39 135.9 16.3 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAX22290.1 - 7.4e-20 71.9 0.0 1.3e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX22290.1 - 1.4e-12 47.4 8.0 2e-12 46.9 8.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAX22290.1 - 0.00018 21.4 0.1 0.00036 20.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GAX22290.1 - 0.0076 16.3 0.2 0.016 15.3 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 GAX22290.1 - 0.041 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GAX22290.1 - 0.05 13.4 0.0 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX22290.1 - 0.053 13.9 0.1 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 GAX22290.1 - 0.12 12.1 0.2 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 GAX22290.1 - 0.16 11.4 0.3 5.8 6.3 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 GAX22290.1 - 1.4 8.9 4.8 2.4 8.2 1.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2569 PF10754.9 GAX22290.1 - 7 7.1 8.1 1.2 9.6 3.8 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2569) CIA30 PF08547.12 GAX22291.1 - 3.4e-19 69.4 0.0 4.3e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) adh_short PF00106.25 GAX22292.1 - 6.9e-26 90.9 0.1 8.8e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX22292.1 - 6.7e-21 74.9 0.0 8.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Oxidored_nitro PF00148.19 GAX22292.1 - 0.0006 18.6 0.0 0.00086 18.1 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase KR PF08659.10 GAX22292.1 - 0.0042 17.0 1.0 0.0085 16.0 0.7 1.7 1 1 1 2 2 2 1 KR domain ADH_zinc_N PF00107.26 GAX22292.1 - 0.0044 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UCH_C PF18031.1 GAX22292.1 - 0.093 12.6 0.9 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases RmlD_sub_bind PF04321.17 GAX22292.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 GAX22292.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 GAX22293.1 - 4.5e-83 279.2 0.0 5.9e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAX22293.1 - 5.8e-23 81.7 0.1 1.1e-22 80.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAX22293.1 - 7.3e-21 73.8 0.4 3e-20 71.9 0.4 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Aldo_ket_red PF00248.21 GAX22294.1 - 3.6e-38 131.4 0.0 3.1e-36 125.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Lactamase_B PF00753.27 GAX22296.1 - 2.1e-15 57.2 0.4 5.7e-15 55.8 0.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAX22296.1 - 4.5e-06 26.3 0.0 6.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_5 PF12695.7 GAX22297.1 - 7.9e-20 71.3 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX22297.1 - 0.00014 21.2 2.8 2.5 7.3 0.1 3.3 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 GAX22297.1 - 0.057 13.1 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase zf-UBR PF02207.20 GAX22299.1 - 1.2e-17 63.8 13.8 1.2e-17 63.8 13.8 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ABC_tran PF00005.27 GAX22300.1 - 8.5e-45 152.6 0.0 1.8e-26 93.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAX22300.1 - 6.2e-39 134.3 34.9 1.8e-24 86.9 17.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAX22300.1 - 1.2e-10 41.3 5.3 0.0033 16.9 0.1 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX22300.1 - 9.9e-08 32.1 0.2 0.078 12.8 0.0 4.3 4 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAX22300.1 - 5.6e-05 23.2 0.2 0.025 14.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX22300.1 - 0.00023 20.9 0.6 0.61 9.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAX22300.1 - 0.00074 19.9 0.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAX22300.1 - 0.0035 17.3 0.1 0.52 10.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GAX22300.1 - 0.009 16.1 1.8 3.2 7.8 0.1 2.7 3 0 0 3 3 3 2 Dynamin family SbcCD_C PF13558.6 GAX22300.1 - 0.016 15.4 0.0 6.3 7.1 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAX22300.1 - 0.022 15.3 0.1 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX22300.1 - 0.048 13.2 0.1 9.9 5.6 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAX22300.1 - 0.051 13.3 0.3 4 7.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 GAX22300.1 - 0.064 12.5 0.1 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 GAX22300.1 - 0.15 11.6 0.1 17 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX22300.1 - 0.19 12.0 0.2 9.1 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 GAX22300.1 - 0.23 10.2 1.7 0.87 8.3 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Beta_helix PF13229.6 GAX22301.1 - 0.16 11.8 14.2 0.28 11.0 2.5 2.6 3 0 0 3 3 3 0 Right handed beta helix region GLTT PF01744.20 GAX22301.1 - 0.48 10.2 38.4 3.7 7.4 2.5 5.6 2 1 1 5 5 5 0 GLTT repeat (6 copies) Mito_carr PF00153.27 GAX22302.1 - 7.3e-60 198.9 0.0 4.8e-20 71.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_8 PF13833.6 GAX22302.1 - 1.2e-10 41.1 0.1 9.2e-07 28.6 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX22302.1 - 3e-07 29.5 0.0 0.004 16.6 0.0 4.8 4 0 0 4 4 4 2 EF hand cNMP_binding PF00027.29 GAX22302.1 - 1.3e-06 28.3 0.0 4.7e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain EF-hand_6 PF13405.6 GAX22302.1 - 4.9e-06 26.0 0.6 0.018 14.9 0.0 4.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 GAX22302.1 - 7.1e-06 26.4 2.0 0.0047 17.3 0.0 3.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 GAX22302.1 - 0.0051 16.3 0.3 0.15 11.6 0.0 3.4 3 0 0 3 3 3 1 EF hand AAA_18 PF13238.6 GAX22304.1 - 3.9e-05 24.2 0.0 0.00011 22.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 GAX22304.1 - 0.0008 19.2 0.0 0.0021 17.8 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 GAX22304.1 - 0.0031 16.8 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin2 PF13189.6 GAX22304.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.6 GAX22304.1 - 0.0057 16.9 3.3 0.011 16.0 0.2 2.9 2 2 0 2 2 2 1 AAA domain DnaB_C PF03796.15 GAX22304.1 - 0.0087 15.4 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAX22304.1 - 0.0088 16.3 0.1 0.032 14.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 GAX22304.1 - 0.0092 15.2 0.2 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 GAX22304.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GAX22304.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 GAX22304.1 - 0.014 15.1 0.2 0.059 13.1 0.1 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_16 PF13191.6 GAX22304.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 GAX22304.1 - 0.022 15.2 0.1 0.083 13.3 0.1 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 GAX22304.1 - 0.05 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GAX22304.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 GAX22304.1 - 0.073 12.8 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 GAX22304.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX22304.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX22304.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAX22304.1 - 0.13 12.7 0.1 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 GAX22304.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 GAX22304.1 - 0.14 12.0 0.2 1.3 8.9 0.0 2.2 1 1 1 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.6 GAX22304.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAX22304.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 GAX22304.1 - 0.52 10.1 1.7 1.5 8.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain JHD PF17811.1 GAX22305.1 - 9.2e-11 42.2 0.1 2.5e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 GAX22305.1 - 5.1e-08 33.3 0.1 3.6e-07 30.6 0.0 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GAX22305.1 - 2.9e-06 27.2 0.0 7.1e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain CheR_N PF03705.15 GAX22305.1 - 0.032 14.0 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain Tim17 PF02466.19 GAX22306.1 - 3.6e-13 49.9 1.9 1.2e-12 48.2 1.9 1.9 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NmrA PF05368.13 GAX22307.1 - 6.3e-24 84.8 0.0 8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAX22307.1 - 1.6e-11 44.4 0.0 3e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX22307.1 - 0.0016 17.5 0.1 0.0022 17.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 GAX22307.1 - 0.0019 18.4 0.1 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAX22307.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 GAX22307.1 - 0.027 14.4 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 GAX22307.1 - 0.031 14.7 0.2 0.058 13.8 0.2 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX22307.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAX22307.1 - 0.1 12.1 0.3 0.17 11.3 0.2 1.5 1 1 0 1 1 1 0 short chain dehydrogenase RINGv PF12906.7 GAX22309.1 - 1.7e-06 28.1 4.0 1.7e-06 28.1 4.0 3.0 3 0 0 3 3 3 1 RING-variant domain zf-MYND PF01753.18 GAX22309.1 - 3.7e-05 23.7 16.6 3.7e-05 23.7 16.6 2.2 2 0 0 2 2 2 1 MYND finger TPR_2 PF07719.17 GAX22310.1 - 1.2e-22 78.2 11.9 0.00082 19.3 0.0 9.0 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAX22310.1 - 1.9e-18 65.0 0.6 0.0074 16.4 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX22310.1 - 1.3e-17 62.8 2.1 0.00015 21.5 0.0 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX22310.1 - 7.3e-10 38.8 21.5 6.3 7.9 1.1 10.0 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX22310.1 - 8.6e-09 34.8 6.3 0.08 13.0 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX22310.1 - 5.1e-08 32.5 3.1 0.14 11.9 0.0 5.7 6 1 1 7 7 7 2 TPR repeat TPR_12 PF13424.6 GAX22310.1 - 1.1e-07 32.1 12.8 0.00085 19.6 0.9 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX22310.1 - 2e-07 31.5 6.1 0.053 14.2 0.0 5.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX22310.1 - 1.3e-06 28.1 7.5 0.057 13.3 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX22310.1 - 2e-06 28.2 2.8 6.8 7.3 0.0 6.3 5 1 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX22310.1 - 0.00027 21.1 19.9 0.00083 19.5 0.7 5.6 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAX22310.1 - 0.00077 19.7 0.3 12 6.5 0.0 5.9 7 1 0 7 7 6 0 Tetratricopeptide repeat Mod_r PF07200.13 GAX22310.1 - 0.024 14.7 1.4 0.055 13.6 1.4 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TPR_9 PF13371.6 GAX22310.1 - 0.12 12.5 9.7 18 5.5 0.5 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat DDT PF02791.17 GAX22310.1 - 0.16 12.3 0.3 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 DDT domain TPR_MalT PF17874.1 GAX22310.1 - 0.69 9.2 10.7 5.4 6.3 0.8 3.5 3 0 0 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 GAX22310.1 - 0.81 10.5 5.6 72 4.3 0.0 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat PI-PLC-X PF00388.19 GAX22311.1 - 1.2e-46 157.9 0.0 2.9e-46 156.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAX22311.1 - 1.3e-37 128.6 0.2 3e-37 127.5 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 GAX22311.1 - 2.5e-12 47.0 0.0 6.4e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain Filament_head PF04732.14 GAX22311.1 - 5.7 7.9 9.4 1.1 10.1 1.5 2.7 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Pyr_redox_2 PF07992.14 GAX22312.1 - 3.7e-52 177.4 0.1 4.8e-52 177.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX22312.1 - 1.4e-17 63.9 0.0 2.6e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX22312.1 - 1e-13 51.7 4.3 1.9e-12 47.6 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 GAX22312.1 - 3.1e-08 34.1 0.0 1.3e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 GAX22312.1 - 3e-05 23.4 0.1 0.00026 20.3 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX22312.1 - 0.0004 20.6 0.3 0.15 12.3 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 GAX22312.1 - 0.0084 16.5 0.1 0.31 11.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAX22312.1 - 0.092 11.8 1.2 2.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAX22312.1 - 0.65 10.0 5.2 4.3 7.3 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 GAX22312.1 - 5 5.7 4.9 49 2.5 0.4 3.0 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.29 GAX22313.1 - 9.3e-32 110.2 0.0 3e-28 98.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX22313.1 - 2e-08 33.9 0.1 5.3e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX22313.1 - 1.1e-07 32.4 0.3 0.0026 18.1 0.0 3.8 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAX22313.1 - 4.5e-07 30.2 0.1 0.0019 18.5 0.0 4.4 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 GAX22313.1 - 3e-05 24.0 0.0 0.0017 18.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX22313.1 - 0.00014 21.3 0.0 0.00039 19.9 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAX22313.1 - 0.00036 20.9 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 GAX22313.1 - 0.00041 20.1 1.0 0.022 14.5 0.1 3.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 GAX22313.1 - 0.00076 19.4 0.6 0.05 13.5 0.0 3.1 3 1 0 3 3 2 1 NACHT domain TsaE PF02367.17 GAX22313.1 - 0.00089 19.3 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GAX22313.1 - 0.001 19.6 0.0 0.027 15.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAX22313.1 - 0.0031 18.0 0.0 0.1 13.1 0.0 2.7 2 1 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 GAX22313.1 - 0.0046 16.7 0.8 0.011 15.5 0.1 2.2 2 1 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 GAX22313.1 - 0.0048 17.1 0.2 1.1 9.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 GAX22313.1 - 0.0064 16.1 0.3 0.45 10.0 0.0 3.6 4 1 0 4 4 4 1 AAA domain TIP49 PF06068.13 GAX22313.1 - 0.013 14.8 0.1 0.028 13.6 0.1 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 GAX22313.1 - 0.017 15.5 0.2 0.67 10.3 0.0 3.1 2 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 GAX22313.1 - 0.02 14.6 0.2 0.089 12.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 GAX22313.1 - 0.022 13.8 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 GAX22313.1 - 0.026 14.0 0.2 0.43 10.1 0.0 2.7 2 1 1 3 3 3 0 P-loop containing dynein motor region AAA_28 PF13521.6 GAX22313.1 - 0.035 14.4 0.1 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAX22313.1 - 0.037 13.8 0.7 0.74 9.6 0.0 3.0 3 1 1 4 4 3 0 AAA domain AAA_14 PF13173.6 GAX22313.1 - 0.04 14.0 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAX22313.1 - 0.043 13.7 0.0 2.2 8.2 0.0 2.8 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 GAX22313.1 - 0.052 13.2 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 GAX22313.1 - 0.088 12.6 0.1 1.6 8.6 0.1 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_24 PF13479.6 GAX22313.1 - 0.13 11.9 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 GAX22313.1 - 0.15 12.2 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 GAX22313.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 GAX22313.1 - 0.16 11.4 0.0 0.54 9.7 0.0 1.8 2 0 0 2 2 1 0 PhoH-like protein PIN_6 PF17146.4 GAX22314.1 - 5.8e-29 100.4 0.1 1.8e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 GAX22314.1 - 9.4e-23 80.2 0.3 2.2e-22 79.0 0.3 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Carboxyl_trans PF01039.22 GAX22315.1 - 1.3e-152 508.9 0.0 1.9e-152 508.3 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 GAX22315.1 - 4.4e-126 422.0 0.0 5.5e-126 421.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 GAX22315.1 - 6.8e-51 172.8 0.1 1.6e-50 171.6 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAX22315.1 - 8.6e-25 87.4 0.1 3e-24 85.7 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAX22315.1 - 2e-21 76.1 0.0 4.3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAX22315.1 - 4.3e-11 42.5 0.0 1.4e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 GAX22315.1 - 0.00013 21.6 0.8 0.00081 19.0 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAX22315.1 - 0.00055 19.5 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAX22315.1 - 0.0016 18.5 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Abhydrolase_5 PF12695.7 GAX22315.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family LAL_C2 PF18603.1 GAX22315.1 - 0.12 12.6 0.1 0.73 10.0 0.0 2.4 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Biotin_lipoyl_2 PF13533.6 GAX22315.1 - 0.13 12.1 0.0 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like DAO PF01266.24 GAX22316.1 - 2.8e-40 139.0 0.1 1.5e-39 136.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 GAX22316.1 - 3.4e-35 120.7 0.1 1.1e-34 119.0 0.0 2.0 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 GAX22316.1 - 1.2e-10 41.1 3.6 6e-10 38.8 3.6 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAX22316.1 - 0.00043 19.6 0.2 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX22316.1 - 0.00075 18.9 0.3 0.047 12.9 0.2 2.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAX22316.1 - 0.0087 15.5 1.0 0.0087 15.5 1.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX22316.1 - 0.016 15.7 1.6 0.17 12.5 0.2 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX22316.1 - 0.017 14.4 0.0 0.045 13.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX22316.1 - 0.025 13.7 1.7 1.3 8.0 0.8 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAX22316.1 - 0.041 12.9 0.1 0.11 11.6 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 GAX22316.1 - 0.045 13.6 0.0 0.045 13.6 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 GAX22316.1 - 0.074 13.3 0.8 0.29 11.4 0.8 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX22316.1 - 0.086 12.1 0.4 0.53 9.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Hydrolase_2 PF07486.12 GAX22316.1 - 5.8 7.8 6.0 4.7 8.1 0.0 3.3 3 0 0 3 3 2 0 Cell Wall Hydrolase HI0933_like PF03486.14 GAX22316.1 - 7.4 5.2 7.5 0.14 10.8 0.5 1.6 2 0 0 2 2 2 0 HI0933-like protein FliS PF02561.14 GAX22317.1 - 0.23 11.7 1.8 0.42 10.9 1.8 1.4 1 0 0 1 1 1 0 Flagellar protein FliS Corona_M PF01635.18 GAX22318.1 - 0.0036 16.6 0.4 0.0056 16.0 0.4 1.2 1 0 0 1 1 1 1 Coronavirus M matrix/glycoprotein Peptidase_C14 PF00656.22 GAX22319.1 - 2.5e-45 155.4 1.2 4.8e-36 125.0 0.3 2.0 2 0 0 2 2 2 2 Caspase domain Raptor_N PF14538.6 GAX22319.1 - 0.15 12.0 0.1 4 7.4 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain tRNA-synt_1 PF00133.22 GAX22320.1 - 6.9e-70 236.0 0.9 6.5e-45 153.5 0.0 3.6 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 GAX22320.1 - 1.2e-69 233.5 0.0 2e-69 232.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 GAX22320.1 - 7.8e-26 90.7 0.0 7.3e-17 61.2 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAX22320.1 - 2.7e-15 56.6 0.1 1.1e-14 54.6 0.1 2.0 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GAX22320.1 - 1.1e-05 24.9 0.0 0.0065 15.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 GAX22320.1 - 0.014 14.3 0.1 0.24 10.3 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.25 GAX22320.1 - 0.034 13.5 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 GAX22320.1 - 0.076 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Drf_GBD PF06371.13 GAX22321.1 - 0.12 12.0 1.0 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain HEAT_2 PF13646.6 GAX22321.1 - 0.2 12.1 0.8 2.3 8.7 0.1 2.9 2 1 0 2 2 2 0 HEAT repeats Arm PF00514.23 GAX22321.1 - 0.76 9.9 8.2 5.8 7.1 0.2 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4147 PF13660.6 GAX22322.1 - 6.5e-74 248.3 0.1 9.1e-74 247.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 GAX22322.1 - 6.2e-19 68.2 1.5 1e-18 67.5 0.4 2.0 2 0 0 2 2 2 1 MOFRL family Methyltr_RsmB-F PF01189.17 GAX22323.1 - 1.3e-38 132.7 0.0 2.4e-37 128.5 0.0 2.3 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GAX22323.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase NAM PF02365.15 GAX22323.1 - 0.017 16.1 0.3 1.8 9.5 0.0 2.6 2 0 0 2 2 2 0 No apical meristem (NAM) protein Methyltransf_25 PF13649.6 GAX22324.1 - 1.1e-05 26.0 0.1 5.8e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22324.1 - 0.0014 18.5 0.0 0.0047 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22324.1 - 0.02 15.6 0.0 0.076 13.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22324.1 - 0.076 13.7 0.0 0.24 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain HTH_32 PF13565.6 GAX22325.1 - 1.9 9.2 5.8 5.4 7.7 5.8 1.9 1 1 0 1 1 1 0 Homeodomain-like domain Pkinase PF00069.25 GAX22326.1 - 2.8e-50 171.1 0.0 3.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22326.1 - 2.3e-31 109.0 0.0 3.1e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX22326.1 - 1.4e-06 28.4 0.5 0.00024 21.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAX22326.1 - 5.5e-05 22.8 0.2 0.0011 18.6 0.1 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 GAX22326.1 - 0.00017 21.0 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX22326.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 GAX22326.1 - 0.027 14.1 0.1 0.066 12.8 0.1 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 GAX22326.1 - 0.058 12.4 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF826 PF05696.11 GAX22326.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF826) DUF3347 PF11827.8 GAX22327.1 - 3.1 7.9 19.2 5.4 7.2 19.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF948 PF06103.11 GAX22327.1 - 8.9 6.6 11.2 5.3 7.4 8.7 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF179 PF02622.15 GAX22328.1 - 2.6e-31 108.8 0.0 4.2e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ank_2 PF12796.7 GAX22329.1 - 1.2e-31 109.1 1.2 4.3e-14 52.9 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAX22329.1 - 4.8e-24 83.7 18.5 5.1e-07 29.8 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 GAX22329.1 - 2.4e-21 73.5 8.8 0.00026 21.2 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 GAX22329.1 - 4.3e-20 71.8 7.7 1.2e-09 38.5 0.1 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX22329.1 - 4.4e-19 68.3 14.5 4.4e-05 23.7 0.1 6.4 3 3 4 7 7 7 5 Ankyrin repeats (many copies) Ribosomal_L10 PF00466.20 GAX22330.1 - 5.9e-20 71.3 0.2 1.1e-19 70.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 WD40 PF00400.32 GAX22331.1 - 1e-08 35.7 8.1 2 9.4 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX22331.1 - 1.5e-05 25.2 0.0 0.1 12.9 0.0 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cyclin_N PF00134.23 GAX22332.1 - 1.9e-09 37.3 0.3 4.5e-09 36.1 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAX22332.1 - 3.7e-06 27.4 0.0 6.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin WW PF00397.26 GAX22332.1 - 7.5e-06 25.9 1.0 7.5e-06 25.9 1.0 2.4 2 0 0 2 2 2 1 WW domain 2OG-FeII_Oxy_3 PF13640.6 GAX22333.1 - 2.5e-14 53.9 0.0 7.6e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UspB PF10625.9 GAX22333.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein B (UspB) Pox_C4_C10 PF03336.13 GAX22333.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus C4/C10 protein VHL PF01847.16 GAX22333.1 - 0.12 12.3 0.0 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 VHL beta domain Methyltransf_4 PF02390.17 GAX22334.1 - 1.7e-30 105.8 0.0 1.8e-29 102.4 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 GAX22334.1 - 0.0077 16.9 0.0 0.38 11.5 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22334.1 - 0.058 14.0 0.1 19 6.0 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Get5_C PF18514.1 GAX22335.1 - 0.11 12.2 1.6 0.73 9.6 0.1 2.8 3 0 0 3 3 3 0 Get5 C-terminal domain Myb_DNA-binding PF00249.31 GAX22336.1 - 4.5e-26 90.8 7.1 1.7e-12 47.3 0.2 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX22336.1 - 4.4e-22 78.1 3.7 7.8e-12 45.3 0.4 3.7 2 2 1 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAX22336.1 - 0.00048 20.3 1.0 0.01 16.0 0.1 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 IRF PF00605.17 GAX22336.1 - 0.011 16.0 1.2 0.029 14.7 0.1 2.2 1 1 1 2 2 2 0 Interferon regulatory factor transcription factor Tn7_Tnp_TnsA_C PF08721.11 GAX22336.1 - 0.022 15.4 0.0 2.6 8.7 0.0 2.7 3 0 0 3 3 3 0 TnsA endonuclease C terminal RHH_4 PF13467.6 GAX22336.1 - 0.066 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain Myb_DNA-bind_7 PF15963.5 GAX22336.1 - 0.17 11.8 4.6 0.69 9.8 1.1 3.0 2 1 0 2 2 2 0 Myb DNA-binding like Prominin PF05478.11 GAX22336.1 - 0.19 9.6 0.1 0.23 9.4 0.1 1.0 1 0 0 1 1 1 0 Prominin Peptidase_A22B PF04258.13 GAX22337.1 - 1.3e-81 274.3 4.0 1.3e-81 274.3 4.0 1.3 2 0 0 2 2 2 1 Signal peptide peptidase SPP PF06550.11 GAX22337.1 - 0.26 10.7 17.4 0.0074 15.8 6.3 3.3 2 1 1 3 3 3 0 Signal-peptide peptidase, presenilin aspartyl protease VASt PF16016.5 GAX22338.1 - 2.5e-12 47.5 0.0 7.8e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DEAD PF00270.29 GAX22339.1 - 2.1e-24 86.2 0.0 3.8e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAX22339.1 - 6.4e-07 29.5 0.1 1.3e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 GAX22339.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.5 1 1 0 1 1 1 0 SecA DEAD-like domain Spore_coat_CotO PF14153.6 GAX22339.1 - 0.082 12.8 2.3 0.12 12.2 2.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF1524 PF07510.11 GAX22339.1 - 0.15 12.0 0.3 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) Pkinase PF00069.25 GAX22340.1 - 2.8e-53 181.0 0.0 1.3e-46 159.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22340.1 - 5.5e-52 176.6 0.0 2.2e-50 171.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 GAX22340.1 - 5.5e-25 87.8 0.2 1.4e-11 44.8 0.0 3.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX22340.1 - 1.3e-20 73.4 0.2 4.5e-08 33.5 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX22340.1 - 9.8e-15 54.4 0.2 5.4e-06 26.6 0.0 4.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX22340.1 - 8.3e-14 51.3 0.3 2e-05 24.8 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAX22340.1 - 1.7e-12 46.3 0.1 0.00034 20.8 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat APH PF01636.23 GAX22340.1 - 0.025 14.5 0.1 0.45 10.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX22340.1 - 0.025 13.4 0.6 0.059 12.1 0.0 1.8 3 0 0 3 3 3 0 Fungal protein kinase DUF1843 PF08898.10 GAX22340.1 - 0.074 13.6 0.7 10 6.7 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) AOX PF01786.17 GAX22341.1 - 2.3e-26 92.7 0.3 3.1e-26 92.3 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 GAX22341.1 - 0.11 12.3 0.2 0.44 10.3 0.2 2.0 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 SNAP PF14938.6 GAX22342.1 - 4.6e-11 42.7 10.8 5.7e-08 32.5 5.4 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Histone PF00125.24 GAX22342.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.2 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 TP2 PF01254.18 GAX22342.1 - 2.6 8.7 11.6 3.1 8.4 2.9 3.3 3 0 0 3 3 3 0 Nuclear transition protein 2 FGF-BP1 PF06473.12 GAX22342.1 - 5.5 6.8 9.8 0.87 9.4 2.0 2.6 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) ArfGap PF01412.18 GAX22343.1 - 9.1e-24 83.8 0.4 2e-23 82.7 0.4 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF4602 PF15375.6 GAX22344.1 - 7.6e-21 74.8 7.3 9e-21 74.6 7.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) PhyH PF05721.13 GAX22345.1 - 2e-08 34.8 2.2 1.2e-06 28.9 0.3 2.7 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) Sulfotransfer_3 PF13469.6 GAX22345.1 - 0.057 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Sulfotransferase family DUF5325 PF17259.2 GAX22346.1 - 0.97 9.4 8.4 0.054 13.4 0.9 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5325) ABC1 PF03109.16 GAX22350.1 - 2.5e-24 85.7 0.0 5.9e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GAX22350.1 - 0.017 14.5 0.0 0.071 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain DUF1499 PF07386.11 GAX22351.1 - 5.4e-08 33.4 0.7 7.5e-08 32.9 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1499) DUF1499 PF07386.11 GAX22352.1 - 1.4e-10 41.8 0.8 2.4e-10 41.0 0.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1499) Rieske PF00355.26 GAX22353.1 - 2.5e-11 43.4 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 GAX22353.1 - 1.8e-09 37.4 1.7 1.8e-09 37.4 1.7 2.0 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit Sulf_transp PF04143.14 GAX22354.1 - 4.2e-11 43.0 31.0 4.5e-09 36.3 12.0 3.5 1 1 1 3 3 3 3 Sulphur transport FAM209 PF15206.6 GAX22354.1 - 0.07 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 FAM209 family AAA_23 PF13476.6 GAX22355.1 - 8.5e-25 88.4 3.9 8.5e-25 88.4 3.9 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GAX22355.1 - 4e-16 59.7 1.3 9.3e-16 58.5 1.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAX22355.1 - 1.3e-15 57.4 12.5 1.2e-14 54.3 12.4 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX22355.1 - 2.7e-05 23.8 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GAX22355.1 - 4.4e-05 23.5 0.2 0.00016 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Laminin_II PF06009.12 GAX22355.1 - 0.0011 19.1 1.3 0.0011 19.1 1.3 3.2 3 0 0 3 3 3 1 Laminin Domain II UvrA_DNA-bind PF17755.1 GAX22355.1 - 0.012 16.0 0.4 0.033 14.5 0.1 1.9 2 0 0 2 2 2 0 UvrA DNA-binding domain ABC_tran PF00005.27 GAX22355.1 - 0.31 11.6 0.0 0.31 11.6 0.0 3.3 2 1 0 2 2 2 0 ABC transporter Kelch_1 PF01344.25 GAX22356.1 - 1.5e-51 171.8 25.8 6.1e-11 41.7 1.9 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAX22356.1 - 1.7e-47 159.2 20.6 1.5e-09 37.7 0.1 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAX22356.1 - 1.4e-43 146.4 27.9 3e-10 40.1 0.1 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 GAX22356.1 - 4.3e-42 140.6 26.4 1.2e-09 37.7 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAX22356.1 - 1.5e-40 136.2 25.3 8.4e-09 35.4 1.4 6.3 4 1 2 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAX22356.1 - 2.8e-32 110.2 24.9 6.8e-07 29.1 0.9 6.5 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 GAX22356.1 - 7.8e-23 80.8 0.0 1.2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Phage_T4_gp36 PF03903.13 GAX22356.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Phage T4 tail fibre DNA_pol3_delta2 PF13177.6 GAX22357.1 - 3.3e-15 56.3 0.0 9.4e-15 54.8 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GAX22357.1 - 1.7e-13 51.1 0.0 7.5e-13 49.0 0.0 2.1 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 GAX22357.1 - 4e-12 46.4 0.2 2.9e-11 43.6 0.1 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 GAX22357.1 - 6.7e-07 29.7 0.0 2.3e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX22357.1 - 2.2e-06 28.2 0.2 8.8e-05 22.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain ResIII PF04851.15 GAX22357.1 - 1.7e-05 24.9 0.0 0.0034 17.4 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 GAX22357.1 - 1.9e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 GAX22357.1 - 6.1e-05 23.4 0.0 0.00021 21.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX22357.1 - 0.0001 22.3 0.0 0.062 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 GAX22357.1 - 0.00012 21.5 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 GAX22357.1 - 0.0004 20.1 0.0 0.0038 17.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 GAX22357.1 - 0.00048 20.1 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 GAX22357.1 - 0.00065 19.1 0.0 0.0038 16.6 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 GAX22357.1 - 0.0022 17.8 0.0 0.0065 16.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX22357.1 - 0.0034 17.1 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAX22357.1 - 0.0036 17.7 0.0 0.041 14.3 0.0 2.5 2 2 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 GAX22357.1 - 0.0068 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 GAX22357.1 - 0.0087 15.6 0.0 0.033 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 GAX22357.1 - 0.011 15.1 0.0 0.056 12.9 0.0 2.1 3 0 0 3 3 3 0 Bacterial TniB protein AAA_assoc_2 PF16193.5 GAX22357.1 - 0.012 15.9 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain IstB_IS21 PF01695.17 GAX22357.1 - 0.017 14.9 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 GAX22357.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DEAD PF00270.29 GAX22357.1 - 0.018 14.8 0.0 3.8 7.2 0.0 2.5 1 1 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 GAX22357.1 - 0.022 14.1 0.0 10 5.4 0.0 2.8 2 1 1 3 3 3 0 Zeta toxin PhoH PF02562.16 GAX22357.1 - 0.023 14.1 0.0 0.59 9.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activ_2 PF14532.6 GAX22357.1 - 0.034 14.3 0.0 1.6 8.8 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 GAX22357.1 - 0.036 14.2 0.0 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 GAX22357.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain MeaB PF03308.16 GAX22357.1 - 0.041 12.9 0.1 0.54 9.2 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 GAX22357.1 - 0.059 13.9 0.0 0.18 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX22357.1 - 0.073 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAX22357.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAX22357.1 - 0.19 11.2 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_L17 PF01196.19 GAX22358.1 - 5.6e-33 113.7 0.3 6.7e-33 113.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Acyltransferase PF01553.21 GAX22360.1 - 2.1e-17 63.0 0.0 3.7e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Mpv17_PMP22 PF04117.12 GAX22361.1 - 8e-21 74.0 0.2 1.5e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 GAX22362.1 - 1.4e-16 60.4 2.9 2.7e-16 59.5 2.9 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Glycolytic PF00274.19 GAX22363.1 - 6.8e-12 44.8 0.0 6.5e-11 41.6 0.0 1.9 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-I FBPase PF00316.20 GAX22364.1 - 2.7e-47 160.7 0.0 3.7e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain FBPase PF00316.20 GAX22365.1 - 1.5e-44 151.7 0.1 3e-44 150.8 0.1 1.5 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain FBPase PF00316.20 GAX22366.1 - 7.1e-32 110.4 0.0 1.2e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DUF3653 PF12375.8 GAX22366.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Phage protein zf-DNL PF05180.12 GAX22366.1 - 0.051 13.5 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 DNL zinc finger Coat_F PF07875.12 GAX22366.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Coat F domain MMR_HSR1 PF01926.23 GAX22367.1 - 3.3e-45 152.8 0.0 2.4e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 GAX22367.1 - 2.7e-31 107.7 0.0 6.5e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 GAX22367.1 - 9.5e-16 57.7 0.0 1.3e-06 28.0 0.0 2.5 2 1 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAX22367.1 - 2.1e-13 50.2 0.2 3.7e-08 33.1 0.0 4.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAX22367.1 - 1.5e-10 41.4 0.2 0.063 13.3 0.0 4.4 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 GAX22367.1 - 3.5e-10 39.6 0.1 6.4e-06 25.6 0.0 3.3 3 1 0 3 3 3 2 AIG1 family RsgA_GTPase PF03193.16 GAX22367.1 - 5.4e-07 29.7 0.1 0.27 11.1 0.0 3.8 4 0 0 4 4 4 2 RsgA GTPase ABC_tran PF00005.27 GAX22367.1 - 5.7e-06 26.9 0.0 0.15 12.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter TniB PF05621.11 GAX22367.1 - 2.4e-05 23.8 0.0 0.22 10.9 0.0 2.6 2 0 0 2 2 2 2 Bacterial TniB protein AAA_16 PF13191.6 GAX22367.1 - 3.9e-05 24.1 0.0 0.56 10.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain Roc PF08477.13 GAX22367.1 - 7.4e-05 23.0 0.0 0.88 9.8 0.0 3.5 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 GAX22367.1 - 0.00043 20.1 0.0 0.052 13.3 0.0 3.7 4 1 0 4 4 3 1 Ethanolamine utilisation - propanediol utilisation GBP PF02263.19 GAX22367.1 - 0.0067 15.7 0.0 0.79 8.9 0.0 2.2 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain AAA_29 PF13555.6 GAX22367.1 - 0.014 15.1 0.0 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 GAX22367.1 - 0.02 14.0 0.0 0.59 9.2 0.0 2.6 3 0 0 3 3 3 0 MCM P-loop domain cobW PF02492.19 GAX22367.1 - 0.027 14.1 0.1 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 GAX22367.1 - 0.031 13.9 0.1 16 5.1 0.0 3.5 3 1 0 3 3 3 0 Ras family AAA_15 PF13175.6 GAX22367.1 - 0.039 13.7 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GAX22367.1 - 0.042 14.1 0.0 7.1 6.9 0.0 3.1 2 2 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAX22367.1 - 0.048 13.6 0.3 19 5.1 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.6 GAX22367.1 - 0.055 13.2 0.0 2.2 8.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 GAX22367.1 - 0.057 14.0 0.0 3.8 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAX22367.1 - 0.072 12.3 0.0 8.2 5.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_21 PF13304.6 GAX22367.1 - 0.081 12.7 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 GAX22367.1 - 0.083 12.8 0.0 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 GAX22367.1 - 0.11 12.9 0.0 12 6.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 GAX22367.1 - 0.12 12.8 0.0 19 5.7 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SIS PF01380.22 GAX22367.1 - 0.15 11.9 0.0 0.54 10.1 0.0 1.9 1 0 0 1 1 1 0 SIS domain BAF PF02961.14 GAX22368.1 - 1.5e-05 25.3 0.0 2.7e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Barrier to autointegration factor HHH_5 PF14520.6 GAX22368.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain AAA PF00004.29 GAX22369.1 - 4.2e-39 134.0 0.0 9.4e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAX22369.1 - 5.1e-18 64.8 0.2 1.2e-17 63.6 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAX22369.1 - 1.4e-11 44.0 0.2 3.6e-11 42.7 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAX22369.1 - 1.3e-06 28.4 0.2 1.5e-05 25.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX22369.1 - 1.5e-06 28.4 0.0 6e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAX22369.1 - 1.3e-05 25.7 0.2 5.4e-05 23.6 0.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX22369.1 - 5.5e-05 23.5 0.1 0.0017 18.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAX22369.1 - 0.00015 21.5 0.2 0.00082 19.2 0.2 2.2 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 GAX22369.1 - 0.0015 18.4 1.4 0.097 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX22369.1 - 0.0018 18.4 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF812 PF05667.11 GAX22369.1 - 0.004 16.1 1.6 0.0063 15.5 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_3 PF07726.11 GAX22369.1 - 0.013 15.4 0.5 0.043 13.7 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAX22369.1 - 0.013 15.2 0.1 0.076 12.7 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 GAX22369.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 GAX22369.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Transcrip_act PF04949.13 GAX22369.1 - 0.027 14.3 1.6 0.027 14.3 1.6 1.9 2 0 0 2 2 2 0 Transcriptional activator Mg_chelatase PF01078.21 GAX22369.1 - 0.031 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 GAX22369.1 - 0.044 13.2 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Atg14 PF10186.9 GAX22369.1 - 0.074 12.1 3.5 0.13 11.3 3.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CPT PF07931.12 GAX22369.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 GAX22369.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 GAX22369.1 - 0.096 12.0 0.5 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 GAX22369.1 - 0.15 12.7 1.2 0.75 10.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 GAX22369.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAX22369.1 - 0.2 12.1 2.1 5 7.6 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Cwf_Cwc_15 PF04889.12 GAX22370.1 - 1.9 8.1 14.7 2.6 7.7 14.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_12 PF13424.6 GAX22371.1 - 3.6e-33 113.7 23.9 3e-10 40.2 0.3 8.7 8 2 1 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX22371.1 - 2.6e-27 93.5 15.5 1.8e-05 24.3 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX22371.1 - 2.9e-22 76.9 21.2 0.00086 19.2 0.1 9.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAX22371.1 - 2.3e-17 62.2 16.2 0.00017 21.3 0.0 9.1 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX22371.1 - 6e-17 60.4 16.9 0.00057 19.9 0.1 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAX22371.1 - 1e-14 53.4 12.0 1.5e-06 27.8 0.1 6.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX22371.1 - 2e-05 25.2 9.8 0.2 12.3 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX22371.1 - 3.3e-05 23.4 2.4 0.11 11.8 0.2 3.7 3 1 1 4 4 4 2 MalT-like TPR region TPR_6 PF13174.6 GAX22371.1 - 0.00011 22.5 6.5 1.2 10.0 0.0 6.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX22371.1 - 0.00042 20.9 8.2 14 6.8 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX22371.1 - 0.0028 17.9 6.9 56 4.4 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX22371.1 - 0.0045 17.1 3.9 31 4.8 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat PUFD PF16553.5 GAX22371.1 - 0.043 13.9 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain Med2 PF11214.8 GAX22371.1 - 0.045 13.9 0.1 0.16 12.1 0.1 1.9 1 0 0 1 1 1 0 Mediator complex subunit 2 TPR_11 PF13414.6 GAX22371.1 - 2.9 7.6 0.0 2.9 7.6 0.0 5.4 8 0 0 8 8 8 0 TPR repeat DUF760 PF05542.11 GAX22372.1 - 2e-39 133.8 0.4 8.7e-19 67.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) PP-binding PF00550.25 GAX22373.1 - 7.8e-14 51.8 0.4 1.1e-13 51.3 0.4 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAX22373.1 - 6e-05 23.2 0.3 8.2e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-carrier COPIIcoated_ERV PF07970.12 GAX22374.1 - 2e-64 217.5 0.2 3.2e-64 216.8 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX22374.1 - 2.8e-25 88.5 0.1 4.8e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Chloroa_b-bind PF00504.21 GAX22375.1 - 1.6e-20 74.3 0.0 2.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SDH_C PF18317.1 GAX22375.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain DUF572 PF04502.13 GAX22376.1 - 2.1e-23 83.5 13.6 4.9e-23 82.3 13.6 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) S1 PF00575.23 GAX22377.1 - 9.4e-12 45.1 0.0 2.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Rsd_AlgQ PF04353.13 GAX22378.1 - 0.024 14.6 0.2 0.039 13.9 0.2 1.4 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Mpv17_PMP22 PF04117.12 GAX22379.1 - 1.3e-12 47.8 0.4 2.1e-12 47.1 0.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pro_isomerase PF00160.21 GAX22380.1 - 4.7e-17 62.7 0.0 7.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3826 PF12875.7 GAX22381.1 - 0.051 13.7 0.2 0.094 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) zf-RING_UBOX PF13445.6 GAX22382.1 - 1.7e-08 34.3 8.3 4.7e-08 32.9 8.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX22382.1 - 4.8e-08 32.7 6.8 4.8e-08 32.7 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX22382.1 - 6.6e-08 32.3 8.2 6.6e-08 32.3 8.2 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX22382.1 - 8.6e-08 31.9 9.0 8.6e-08 31.9 9.0 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX22382.1 - 4.7e-07 29.7 8.0 4.7e-07 29.7 8.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAX22382.1 - 2e-06 28.0 8.3 2e-06 28.0 8.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAX22382.1 - 3.6e-05 23.8 8.6 3.6e-05 23.8 8.6 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAX22382.1 - 5.9e-05 22.9 5.3 0.00013 21.7 5.3 1.6 1 1 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 GAX22382.1 - 0.00019 21.2 6.3 0.00019 21.2 6.3 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAX22382.1 - 0.0013 18.9 5.6 0.0013 18.9 5.6 3.0 3 0 0 3 3 3 1 zinc RING finger of MSL2 SAP PF02037.27 GAX22382.1 - 0.0014 18.3 0.3 0.0014 18.3 0.3 1.8 2 0 0 2 2 1 1 SAP domain zf-rbx1 PF12678.7 GAX22382.1 - 0.0081 16.4 5.8 0.033 14.5 5.8 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 GAX22382.1 - 0.019 14.8 7.2 0.044 13.6 6.4 2.1 2 1 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2225 PF09986.9 GAX22382.1 - 0.032 13.9 2.8 0.14 11.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RanBP PF00641.18 GAX22382.1 - 0.25 10.7 12.7 0.042 13.2 7.0 2.7 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ANAPC11 PF12861.7 GAX22382.1 - 0.75 9.9 6.1 0.14 12.2 1.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spt4 PF06093.13 GAX22382.1 - 1.8 8.7 5.9 0.92 9.7 0.9 2.7 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger OrfB_Zn_ribbon PF07282.11 GAX22382.1 - 8.7 6.4 7.0 5 7.1 0.5 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RNase_PH PF01138.21 GAX22383.1 - 2.7e-11 44.1 1.3 8.4e-10 39.3 0.0 3.1 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX22383.1 - 0.0028 17.7 0.0 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Retinin_C PF04527.12 GAX22383.1 - 0.36 11.1 4.3 0.19 12.0 1.6 1.9 2 0 0 2 2 2 0 Drosophila Retinin like protein ETRAMP PF09716.10 GAX22383.1 - 0.93 9.6 2.5 1.9 8.6 2.5 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3533 PF12051.8 GAX22383.1 - 4.5 6.1 4.8 8 5.3 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MFS_1 PF07690.16 GAX22385.1 - 1.4e-27 96.5 43.6 1.4e-27 96.5 43.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAX22386.1 - 3.3e-28 98.6 36.4 3.3e-28 98.6 36.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily cNMP_binding PF00027.29 GAX22387.1 - 2.7e-05 24.1 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PK PF00224.21 GAX22388.1 - 6.6e-140 465.9 0.3 9.3e-140 465.4 0.3 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAX22388.1 - 1.3e-19 70.6 0.4 4.3e-19 68.9 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAX22388.1 - 0.0026 16.9 0.3 0.007 15.5 0.2 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Methyltransf_23 PF13489.6 GAX22389.1 - 0.00022 21.1 0.1 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ank_2 PF12796.7 GAX22390.1 - 3.2e-08 34.0 0.5 0.018 15.6 0.0 4.9 3 2 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX22390.1 - 3e-07 30.8 0.0 0.28 11.8 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX22390.1 - 8.6e-05 22.8 0.3 13 6.4 0.2 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 GAX22390.1 - 0.00036 20.7 0.1 22 6.0 0.0 5.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 GAX22390.1 - 0.003 17.8 1.4 3.3 8.1 0.0 4.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) HEAT_EZ PF13513.6 GAX22390.1 - 0.05 14.1 3.4 3.1 8.4 0.1 3.8 3 1 1 4 4 4 0 HEAT-like repeat Arm PF00514.23 GAX22390.1 - 0.76 9.9 2.9 4.1 7.6 0.2 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat XPG_I PF00867.18 GAX22391.1 - 2.3e-25 88.8 0.0 7.2e-25 87.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAX22391.1 - 2.5e-21 76.0 0.0 5.9e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_100 PF12899.7 GAX22391.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Alkaline and neutral invertase Tfb4 PF03850.14 GAX22392.1 - 0.1 12.0 2.3 0.15 11.5 1.9 1.5 1 1 0 1 1 1 0 Transcription factor Tfb4 eIF3g PF12353.8 GAX22392.1 - 7.2 7.0 11.3 1.3 9.4 1.3 3.1 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Spond_N PF06468.13 GAX22393.1 - 4.2e-20 72.7 0.0 5.6e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Spondin_N Spond_N PF06468.13 GAX22394.1 - 5.1e-25 88.7 0.0 6.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Spondin_N Metallophos PF00149.28 GAX22395.1 - 3e-13 50.7 4.6 5.6e-13 49.8 4.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAX22395.1 - 9.1e-13 48.9 1.6 3.5e-12 47.0 0.1 2.7 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAX22395.1 - 1.2e-05 25.8 2.0 1.2e-05 25.8 2.0 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PEPcase PF00311.17 GAX22396.1 - 1.3e-255 850.4 0.4 1.5e-255 850.2 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GAX22396.1 - 2.1e-06 26.5 0.0 4.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Methyltransf_16 PF10294.9 GAX22397.1 - 1.3e-27 96.6 0.2 1.6e-27 96.4 0.2 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX22397.1 - 1.3e-06 28.1 0.3 1.8e-06 27.6 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX22397.1 - 0.00023 20.6 1.2 0.00035 20.1 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAX22397.1 - 0.00026 20.8 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22397.1 - 0.00071 20.3 0.0 0.0011 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX22397.1 - 0.0013 19.4 0.1 0.0022 18.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22397.1 - 0.0022 17.8 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX22397.1 - 0.02 14.7 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAX22397.1 - 0.037 13.3 0.2 0.098 11.9 0.1 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase GidB PF02527.15 GAX22397.1 - 0.049 12.9 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 GAX22397.1 - 0.059 14.0 0.1 0.1 13.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Helicase_C PF00271.31 GAX22397.1 - 0.083 13.2 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain HSF_DNA-bind PF00447.17 GAX22399.1 - 5.4e-21 75.0 0.1 1e-20 74.1 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding VWD PF00094.25 GAX22400.1 - 0.0066 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain RGM_C PF06534.13 GAX22400.1 - 0.014 14.9 0.1 0.033 13.7 0.1 1.6 2 0 0 2 2 2 0 Repulsive guidance molecule (RGM) C-terminus IMP2_N PF18590.1 GAX22404.1 - 4.7e-21 75.1 0.0 1.1e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain UNC-93 PF05978.16 GAX22404.1 - 3.2e-12 46.5 6.7 3.2e-12 46.5 6.7 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 GAX22404.1 - 6.3e-11 41.8 26.3 4.5e-10 39.0 26.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Gypsy PF07253.11 GAX22405.1 - 0.1 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein FmrO PF07091.11 GAX22406.1 - 0.036 13.6 0.6 0.048 13.2 0.6 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RIX1 PF08167.12 GAX22406.1 - 0.099 12.4 0.1 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Glyco_transf_25 PF01755.17 GAX22410.1 - 4.7e-05 23.4 11.6 0.0055 16.6 0.2 4.4 3 2 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Tombus_P19 PF03220.13 GAX22410.1 - 0.63 9.7 2.5 9.7 5.9 0.6 2.4 2 0 0 2 2 2 0 Tombusvirus P19 core protein Mur_ligase_M PF08245.12 GAX22411.1 - 1.6e-05 25.0 0.0 8.7e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Sulfotransfer_4 PF17784.1 GAX22412.1 - 5e-51 173.6 0.1 6.9e-51 173.1 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX22412.1 - 0.00041 20.8 0.0 0.026 14.9 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family DUF3377 PF11857.8 GAX22412.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) GrpE PF01025.19 GAX22413.1 - 8.4e-48 162.2 4.6 1.1e-47 161.8 4.6 1.1 1 0 0 1 1 1 1 GrpE DUF3306 PF11748.8 GAX22413.1 - 2.1 9.2 8.0 3.1 8.7 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) EF-hand_7 PF13499.6 GAX22414.1 - 1.8e-34 118.0 15.0 2.3e-15 56.8 3.4 2.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAX22414.1 - 3.7e-32 107.5 17.6 1.7e-08 33.4 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GAX22414.1 - 9.5e-27 90.6 12.6 8.3e-08 31.6 0.3 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAX22414.1 - 6.7e-25 85.4 16.5 2.9e-06 26.5 1.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAX22414.1 - 3.2e-22 78.1 16.6 4.8e-12 45.5 2.7 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 GAX22414.1 - 6.8e-10 39.1 1.6 1.2e-05 25.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAX22414.1 - 4.8e-07 30.1 1.3 0.015 15.7 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAX22414.1 - 9.3e-07 28.8 7.4 0.018 15.0 0.3 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 GAX22414.1 - 1.2e-06 29.3 0.1 0.015 16.2 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain DUF3349 PF11829.8 GAX22414.1 - 0.00025 21.8 0.0 0.26 12.1 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 GAX22414.1 - 0.0005 20.2 1.9 0.41 10.9 0.1 3.6 1 1 2 3 3 3 2 Dockerin type I domain DUF2267 PF10025.9 GAX22414.1 - 0.0021 18.4 0.0 0.0064 16.8 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) FGAR-AT_linker PF18072.1 GAX22414.1 - 0.022 15.3 1.4 12 6.6 0.0 3.5 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain UPF0154 PF03672.13 GAX22414.1 - 0.12 12.4 0.0 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF533 PF04391.12 GAX22414.1 - 0.14 11.7 4.1 0.4 10.2 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF533) RNA_pol_Rpb4 PF03874.16 GAX22414.1 - 0.16 12.3 3.1 0.59 10.5 0.5 2.2 1 1 1 2 2 2 0 RNA polymerase Rpb4 SapB_1 PF05184.15 GAX22414.1 - 0.27 11.3 2.5 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 Cation_efflux PF01545.21 GAX22415.1 - 3.4e-36 124.8 25.3 5.9e-36 124.1 25.3 1.4 1 1 0 1 1 1 1 Cation efflux family NnrS PF05940.12 GAX22416.1 - 0.00031 20.2 1.4 0.00036 20.0 1.4 1.0 1 0 0 1 1 1 1 NnrS protein Connexin PF00029.19 GAX22416.1 - 0.0066 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Connexin DUF998 PF06197.13 GAX22416.1 - 0.0094 15.6 1.0 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF2427 PF10348.9 GAX22416.1 - 0.051 13.4 1.6 2.2 8.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) GPI2 PF06432.11 GAX22416.1 - 0.17 11.3 2.2 0.22 11.0 2.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF872 PF05915.12 GAX22416.1 - 0.91 9.7 3.5 0.5 10.6 0.8 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Corona_NS3b PF03053.14 GAX22416.1 - 1.4 8.6 5.5 3.4 7.4 5.1 1.8 1 1 1 2 2 2 0 ORF3b coronavirus protein DUF5317 PF17248.2 GAX22416.1 - 1.6 8.7 10.6 0.1 12.6 4.5 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5317) 7TMR-DISM_7TM PF07695.11 GAX22416.1 - 2.1 8.2 13.8 3.8 7.4 13.4 1.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF383 PF04063.14 GAX22417.1 - 1.2e-34 119.7 0.0 2e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 GAX22417.1 - 3.7e-10 39.5 0.2 3.9e-09 36.2 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) UPF0167 PF03691.14 GAX22417.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Cas_APE2256 PF09651.10 GAX22417.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Ribosomal_S5 PF00333.20 GAX22419.1 - 4.6e-26 90.6 0.3 1.1e-25 89.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GAX22419.1 - 8.3e-24 82.8 0.0 1.6e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 GAX22419.1 - 1.2 9.7 17.1 2.5 8.7 17.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RabGAP-TBC PF00566.18 GAX22420.1 - 9.7e-11 41.7 9.1 7.6e-10 38.8 7.0 3.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain SKG6 PF08693.10 GAX22420.1 - 0.012 15.0 1.2 0.027 13.9 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Apolipoprotein PF01442.18 GAX22420.1 - 0.53 10.1 7.0 0.14 12.1 3.4 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ribosomal_S17 PF00366.20 GAX22420.1 - 1 9.5 4.6 4.4 7.5 1.7 2.5 2 0 0 2 2 2 0 Ribosomal protein S17 ApoLp-III PF07464.11 GAX22420.1 - 6 6.9 8.1 1.8 8.6 3.6 2.5 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Lactamase_B PF00753.27 GAX22421.1 - 1.4e-11 44.8 1.5 4.8e-10 39.8 1.5 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4585 PF15232.6 GAX22421.1 - 0.54 10.3 0.1 0.54 10.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4585) DUF515 PF04415.12 GAX22421.1 - 7.4 4.8 6.7 10 4.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Utp13 PF08625.11 GAX22422.1 - 0.11 12.4 0.4 5.2 7.0 0.0 2.8 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain BTB_2 PF02214.22 GAX22423.1 - 4e-18 65.6 0.0 7.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22423.1 - 0.00022 21.3 0.0 0.00059 19.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain GlgX_C PF18390.1 GAX22423.1 - 0.13 12.1 0.4 0.37 10.6 0.2 1.8 2 0 0 2 2 2 0 Glycogen debranching enzyme C-terminal domain Peptidase_U32 PF01136.19 GAX22424.1 - 4.1e-85 284.7 0.0 8.3e-73 244.4 0.0 2.7 2 1 0 2 2 2 2 Peptidase family U32 DUF3656 PF12392.8 GAX22424.1 - 9.1e-17 61.7 0.0 3.4e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Collagenase DUF3605 PF12239.8 GAX22425.1 - 4.9e-19 69.2 1.1 6e-18 65.6 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) BTB_2 PF02214.22 GAX22426.1 - 7.6e-17 61.5 0.0 1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX22427.1 - 1.8e-12 47.4 0.0 4.2e-12 46.3 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 GAX22427.1 - 2.2e-05 24.5 0.0 4.4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX22428.1 - 3.5e-16 59.3 0.0 5.4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22428.1 - 0.00041 20.4 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX22429.1 - 7.4e-17 61.5 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF4781 PF16013.5 GAX22429.1 - 0.063 12.1 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) BTB_3 PF16017.5 GAX22429.1 - 0.085 13.0 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain DUF1408 PF07193.11 GAX22429.1 - 0.096 12.8 0.0 0.8 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) BTB_2 PF02214.22 GAX22430.1 - 8.9e-20 70.8 0.0 1.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22430.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX22431.1 - 8.4e-16 58.1 0.2 1.8e-15 57.1 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22431.1 - 3.8e-05 23.7 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TRAF_BIRC3_bd PF16673.5 GAX22431.1 - 0.012 15.3 0.7 0.025 14.4 0.7 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain BTB_2 PF02214.22 GAX22432.1 - 1.7e-14 53.9 0.0 3.9e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22432.1 - 0.00076 19.6 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain COesterase PF00135.28 GAX22432.1 - 0.054 12.4 0.1 1.8 7.3 0.0 2.0 1 1 1 2 2 2 0 Carboxylesterase family BTB_2 PF02214.22 GAX22433.1 - 1.7e-18 66.7 0.0 5e-18 65.2 0.0 1.7 1 1 1 2 2 2 1 BTB/POZ domain BTB_2 PF02214.22 GAX22434.1 - 3.7e-07 30.4 0.0 7.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX22435.1 - 1.1e-18 67.4 0.0 2.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22435.1 - 0.0024 17.9 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX22436.1 - 3.4e-17 62.6 0.0 4.3e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX22437.1 - 1e-13 51.4 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain UPF0542 PF15086.6 GAX22437.1 - 0.41 10.6 2.2 0.72 9.8 2.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 BTB_2 PF02214.22 GAX22438.1 - 1.3e-15 57.6 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain LRR_8 PF13855.6 GAX22439.1 - 6.8e-21 73.8 23.9 3.4e-06 26.7 0.1 6.9 3 1 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 GAX22439.1 - 4e-20 71.6 26.3 0.00091 19.6 0.3 7.3 2 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX22439.1 - 7e-10 38.1 12.3 0.94 10.3 0.4 9.5 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_9 PF14580.6 GAX22439.1 - 0.036 13.6 2.7 0.53 9.8 0.1 2.8 2 1 1 3 3 3 0 Leucine-rich repeat Spo7_2_N PF15407.6 GAX22439.1 - 0.088 12.5 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 LRR_6 PF13516.6 GAX22439.1 - 0.72 10.1 16.8 47 4.4 0.1 8.2 10 0 0 10 10 10 0 Leucine Rich repeat BTB_2 PF02214.22 GAX22440.1 - 7.3e-23 80.7 0.1 3.4e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB_3 PF16017.5 GAX22440.1 - 6.4e-09 35.9 0.1 0.0026 17.8 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain DUF4781 PF16013.5 GAX22440.1 - 0.0035 16.2 0.1 0.037 12.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4781) DUF4158 PF13700.6 GAX22440.1 - 0.15 11.9 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) BTB_2 PF02214.22 GAX22441.1 - 2.1e-24 85.7 0.0 1.1e-12 48.1 0.0 2.2 1 1 1 2 2 2 2 BTB/POZ domain BTB_3 PF16017.5 GAX22441.1 - 0.011 15.8 0.0 2.1 8.5 0.0 2.3 1 1 1 2 2 2 0 BTB/POZ domain DUF4781 PF16013.5 GAX22441.1 - 0.015 14.2 0.0 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) AvrM_N PF18247.1 GAX22441.1 - 0.15 12.0 0.2 3.2 7.8 0.0 2.4 2 1 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain BTB_2 PF02214.22 GAX22442.1 - 1.5e-12 47.7 0.0 2.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22442.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain XAF1_C PF18608.1 GAX22442.1 - 0.029 13.9 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain HTH_psq PF05225.16 GAX22442.1 - 0.088 12.6 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain BTB_2 PF02214.22 GAX22443.1 - 2.8e-15 56.4 0.0 5.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22443.1 - 0.0051 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ABC_tran_CTD PF16326.5 GAX22443.1 - 0.016 15.4 1.0 0.028 14.7 0.3 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 GAX22443.1 - 0.02 14.7 0.2 0.051 13.3 0.2 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF1717 PF05414.11 GAX22443.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) F-box PF00646.33 GAX22444.1 - 0.0012 18.6 0.6 0.0032 17.3 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box PF00646.33 GAX22445.1 - 8.7e-05 22.3 1.3 0.00015 21.5 1.3 1.4 1 0 0 1 1 1 1 F-box domain BTB_2 PF02214.22 GAX22446.1 - 5e-49 164.6 0.0 7.6e-16 58.3 0.0 3.7 4 0 0 4 4 4 3 BTB/POZ domain BTB_3 PF16017.5 GAX22446.1 - 2.2e-05 24.5 0.0 0.16 12.1 0.0 3.5 3 0 0 3 3 3 2 BTB/POZ domain THP2 PF09432.10 GAX22446.1 - 0.045 13.8 0.4 1.2 9.2 0.2 2.6 2 0 0 2 2 2 0 Tho complex subunit THP2 RuvA_N PF01330.21 GAX22446.1 - 0.057 13.5 0.0 11 6.2 0.0 3.4 3 0 0 3 3 3 0 RuvA N terminal domain Angiomotin_C PF12240.8 GAX22446.1 - 0.81 9.2 4.2 0.31 10.6 0.8 1.9 2 0 0 2 2 2 0 Angiomotin C terminal BTB_2 PF02214.22 GAX22447.1 - 3.3e-09 37.0 0.0 5.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22447.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 GAX22448.1 - 4e-16 59.1 0.0 7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX22449.1 - 1.1e-08 35.3 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_3 PF01596.17 GAX22449.1 - 0.07 12.3 1.1 1.3 8.2 0.3 2.2 1 1 1 2 2 2 0 O-methyltransferase DUF4952 PF16310.5 GAX22449.1 - 0.097 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) BTB_2 PF02214.22 GAX22450.1 - 3.5e-16 59.3 0.0 6.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22450.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 GAX22451.1 - 3e-15 56.4 0.0 4.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22451.1 - 0.02 15.0 0.0 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain Glyco_transf_8 PF01501.20 GAX22452.1 - 0.042 13.4 0.0 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 Viral_DNA_bp PF00747.17 GAX22452.1 - 0.18 8.9 0.0 0.26 8.4 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein PK PF00224.21 GAX22454.1 - 1.2e-103 346.7 0.0 1.6e-103 346.3 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAX22454.1 - 6.4e-32 110.2 0.0 1.5e-31 109.1 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 GAX22454.1 - 0.016 14.3 0.0 0.089 11.8 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain WW PF00397.26 GAX22455.1 - 3.7e-06 26.9 2.8 3.7e-06 26.9 2.8 2.2 3 0 0 3 3 3 1 WW domain TMEM154 PF15102.6 GAX22455.1 - 0.012 15.5 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family NYD-SP28 PF14772.6 GAX22455.1 - 0.074 13.1 1.3 0.15 12.1 1.3 1.5 1 0 0 1 1 1 0 Sperm tail FapA PF03961.13 GAX22456.1 - 0.0046 15.6 2.2 0.0046 15.6 2.2 1.8 2 0 0 2 2 2 1 Flagellar Assembly Protein A BLOC1_2 PF10046.9 GAX22456.1 - 2.1 8.7 12.0 1.1 9.6 5.2 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4164 PF13747.6 GAX22456.1 - 7 7.0 11.1 0.71 10.2 3.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CSRNP_N PF16019.5 GAX22457.1 - 8.2e-05 22.6 0.0 0.00018 21.5 0.0 1.5 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus Rgp1 PF08737.10 GAX22457.1 - 0.096 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Rgp1 Glyco_transf_18 PF15024.6 GAX22458.1 - 0.085 11.4 1.8 0.14 10.7 1.8 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 18 Aldo_ket_red PF00248.21 GAX22459.1 - 3.4e-09 36.3 0.2 1.1e-08 34.6 0.1 1.9 2 1 0 2 2 2 1 Aldo/keto reductase family RL PF17797.1 GAX22460.1 - 0.048 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 RL domain zf-C2H2_jaz PF12171.8 GAX22461.1 - 0.0035 17.6 0.1 0.016 15.5 0.1 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAX22461.1 - 0.0044 17.4 0.5 0.0044 17.4 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAX22461.1 - 0.0057 17.4 0.7 0.0057 17.4 0.7 3.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 GAX22461.1 - 0.06 13.8 1.0 0.23 12.0 1.0 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type UIM PF02809.20 GAX22463.1 - 0.0039 17.0 3.4 0.011 15.6 3.4 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif SAP PF02037.27 GAX22464.1 - 3e-11 42.8 0.6 8.1e-11 41.4 0.6 1.8 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 GAX22464.1 - 0.023 14.3 0.1 0.068 12.8 0.1 1.8 1 0 0 1 1 1 0 Telomere stability C-terminal TIP49 PF06068.13 GAX22466.1 - 1.4e-142 475.0 0.0 2.1e-142 474.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Semialdhyde_dhC PF02774.18 GAX22466.1 - 2.5e-46 158.1 0.0 4.9e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GAX22466.1 - 1.6e-27 96.3 0.8 5.6e-27 94.6 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TIP49_C PF17856.1 GAX22466.1 - 1.5e-21 76.3 0.7 3.9e-21 75.0 0.7 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAX22466.1 - 2.4e-08 34.4 0.7 1.2e-05 25.7 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX22466.1 - 9.2e-06 25.5 0.1 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain F420_oxidored PF03807.17 GAX22466.1 - 4.8e-05 23.9 2.8 0.00021 21.8 0.1 3.4 5 0 0 5 5 2 1 NADP oxidoreductase coenzyme F420-dependent AAA_16 PF13191.6 GAX22466.1 - 0.00015 22.2 1.1 0.00082 19.8 1.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 GAX22466.1 - 0.0011 18.4 0.9 0.078 12.3 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX22466.1 - 0.0012 18.9 0.1 0.88 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX22466.1 - 0.0012 19.1 0.1 0.3 11.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAX22466.1 - 0.0028 17.9 0.1 0.0082 16.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX22466.1 - 0.0028 17.8 0.3 0.016 15.3 0.0 2.4 3 0 0 3 3 2 1 AAA domain DnaB_C PF03796.15 GAX22466.1 - 0.0044 16.4 0.1 0.012 15.0 0.1 1.7 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 GAX22466.1 - 0.013 15.2 0.0 4.3 7.0 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 GAX22466.1 - 0.034 13.2 0.4 1.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 GAX22466.1 - 0.048 13.2 0.1 0.18 11.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain Gp_dh_C PF02800.20 GAX22466.1 - 0.049 13.2 0.2 0.32 10.6 0.1 2.4 3 0 0 3 3 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Zeta_toxin PF06414.12 GAX22466.1 - 0.052 12.8 0.2 0.25 10.6 0.0 2.1 2 1 1 3 3 3 0 Zeta toxin AAA_17 PF13207.6 GAX22466.1 - 0.059 13.8 1.1 0.2 12.1 0.1 2.4 2 1 0 2 2 1 0 AAA domain tRNA-synt_2 PF00152.20 GAX22467.1 - 2.5e-73 246.9 0.0 3.5e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX22467.1 - 6.6e-06 26.0 0.0 4e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX22467.1 - 3.4e-05 23.4 0.2 0.026 14.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FAD_binding_1 PF00667.20 GAX22468.1 - 1.4e-21 77.1 0.0 2.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX22468.1 - 9.5e-19 68.0 0.0 1.9e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAX22468.1 - 6.7e-10 39.6 0.0 1.5e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DNA_topoisoIV PF00521.20 GAX22469.1 - 3.3e-124 415.0 0.0 9.4e-123 410.3 0.0 2.2 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAX22469.1 - 1.2e-36 125.8 4.7 1.4e-34 119.2 4.7 2.9 1 1 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAX22469.1 - 4e-22 78.5 1.0 4e-22 78.5 1.0 2.0 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 GAX22469.1 - 8.8e-12 45.5 0.0 2.3e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAX22469.1 - 8.3e-08 32.4 0.0 3.7e-07 30.3 0.0 2.2 1 0 0 1 1 1 1 Toprim domain CHCH PF06747.13 GAX22470.1 - 0.0028 17.8 12.4 0.0038 17.3 12.4 1.2 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.17 GAX22470.1 - 0.065 13.5 4.1 0.096 12.9 4.1 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 GAX22470.1 - 0.072 13.1 8.3 0.11 12.5 8.3 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Na_K-ATPase PF00287.18 GAX22470.1 - 0.14 11.3 5.0 0.18 10.9 5.0 1.1 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain DUF2985 PF11204.8 GAX22471.1 - 8.3e-10 38.7 2.5 8.3e-10 38.7 2.5 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2985) F-box PF00646.33 GAX22473.1 - 0.04 13.8 0.2 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 GAX22473.1 - 0.075 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box NIF PF03031.18 GAX22473.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Ubiq_cyt_C_chap PF03981.12 GAX22474.1 - 3e-09 37.1 0.9 4.5e-09 36.5 0.9 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 GAX22474.1 - 4.6e-06 26.6 2.2 1e-05 25.5 2.2 1.6 1 0 0 1 1 1 1 WW domain Zn-ribbon_8 PF09723.10 GAX22475.1 - 7.8e-05 22.7 0.6 0.00014 21.9 0.6 1.4 1 0 0 1 1 1 1 Zinc ribbon domain A2L_zn_ribbon PF08792.10 GAX22475.1 - 0.00044 19.9 0.7 0.0057 16.3 0.2 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 GAX22475.1 - 0.0047 16.4 4.2 0.077 12.5 0.2 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding zf-trcl PF13451.6 GAX22475.1 - 0.0082 16.0 1.3 0.46 10.4 1.9 2.4 1 1 1 2 2 2 1 Probable zinc-ribbon domain HypA PF01155.19 GAX22475.1 - 0.0087 16.1 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 GAX22475.1 - 0.0089 15.9 0.2 0.016 15.1 0.2 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 GAX22475.1 - 0.023 14.1 5.4 0.94 9.0 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 GAX22475.1 - 0.027 14.6 4.7 0.65 10.1 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Nudix_N_2 PF14803.6 GAX22475.1 - 0.033 14.1 0.6 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal Mu-like_Com PF10122.9 GAX22475.1 - 0.043 13.3 0.3 0.073 12.5 0.3 1.3 1 0 0 1 1 1 0 Mu-like prophage protein Com zinc_ribbon_10 PF10058.9 GAX22475.1 - 0.059 13.1 0.2 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Auto_anti-p27 PF06677.12 GAX22475.1 - 0.1 12.8 0.7 2.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_ribbon_SprT PF17283.2 GAX22475.1 - 0.1 12.5 1.1 0.32 10.9 1.3 1.7 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Rubredoxin PF00301.20 GAX22475.1 - 0.14 12.2 8.6 1.1 9.3 1.4 2.5 1 1 1 2 2 2 0 Rubredoxin zf-HIT PF04438.16 GAX22475.1 - 0.43 10.5 4.1 4.1 7.4 0.9 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-H2C2_2 PF13465.6 GAX22475.1 - 2.1 8.9 6.1 12 6.6 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Rubredoxin_2 PF18073.1 GAX22475.1 - 3.1 7.6 9.1 0.51 10.1 0.3 2.9 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-C2H2 PF00096.26 GAX22475.1 - 5.3 7.7 8.5 0.87 10.2 1.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Transket_pyr PF02779.24 GAX22476.1 - 5.5e-44 150.0 0.1 7.7e-44 149.5 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX22476.1 - 5.4e-34 116.7 0.0 9.6e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain bZIP_1 PF00170.21 GAX22477.1 - 0.0021 18.1 15.5 0.01 15.9 15.0 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX22477.1 - 0.039 14.0 8.0 0.039 14.0 8.0 2.7 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 GAX22477.1 - 0.27 11.8 13.9 0.62 10.6 13.8 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor HNOBA PF07701.14 GAX22477.1 - 0.76 9.2 7.2 0.21 11.0 3.9 1.7 1 1 1 2 2 2 0 Heme NO binding associated GvpL_GvpF PF06386.11 GAX22477.1 - 0.96 9.3 7.0 1.3 8.9 7.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SlyX PF04102.12 GAX22477.1 - 1.4 9.6 8.1 6.8 7.4 8.1 2.2 1 1 0 1 1 1 0 SlyX DUF4140 PF13600.6 GAX22477.1 - 1.6 9.2 7.4 5.7 7.4 7.4 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MTD PF01993.18 GAX22479.1 - 0.15 11.4 0.2 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HAD_2 PF13419.6 GAX22480.1 - 1.3e-18 67.8 0.0 2.7e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX22480.1 - 1e-09 39.0 0.0 2.4e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX22480.1 - 1.6e-07 31.3 0.1 4.9e-07 29.7 0.1 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 GAX22480.1 - 0.0059 17.0 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ClpS PF02617.17 GAX22481.1 - 2.5e-08 33.6 0.6 4.6e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS DUF3591 PF12157.8 GAX22481.1 - 0.061 12.0 0.6 0.082 11.6 0.6 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3591) Kelch_5 PF13854.6 GAX22482.1 - 2.9e-30 103.7 0.1 5.1e-05 23.1 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 GAX22482.1 - 1.9e-29 101.4 9.8 3.7e-05 23.6 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAX22482.1 - 2.1e-23 82.1 18.7 1.8e-06 28.1 0.1 7.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GAX22482.1 - 8.8e-22 76.2 13.0 1.4e-05 24.8 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAX22482.1 - 8.7e-18 63.9 9.4 0.0065 16.7 0.1 5.7 4 1 1 5 5 5 5 Kelch motif Kelch_1 PF01344.25 GAX22482.1 - 1.1e-14 53.7 11.5 7.5e-07 28.6 0.2 5.6 5 1 0 5 5 5 3 Kelch motif GlyL_C PF12524.8 GAX22482.1 - 0.036 14.2 0.6 22 5.3 0.0 3.5 3 1 0 3 3 3 0 dsDNA virus glycoprotein L C terminal zf-C4H2 PF10146.9 GAX22482.1 - 0.19 12.0 4.2 0.29 11.4 4.2 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein FA_desaturase PF00487.24 GAX22486.1 - 0.0099 15.7 2.0 0.014 15.3 2.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF5313 PF17240.2 GAX22486.1 - 0.15 12.5 0.4 0.28 11.6 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Ank_2 PF12796.7 GAX22487.1 - 6.6e-29 100.3 0.0 2.1e-09 37.8 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX22487.1 - 8.7e-27 93.1 0.4 3.6e-10 40.2 0.0 5.1 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX22487.1 - 3.8e-19 68.5 2.6 3e-08 33.8 0.3 5.5 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX22487.1 - 7.9e-18 64.0 0.1 0.023 15.1 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 GAX22487.1 - 3.2e-17 60.8 0.0 0.028 14.9 0.0 7.5 7 0 0 7 7 7 3 Ankyrin repeat mTERF PF02536.14 GAX22487.1 - 1.3e-07 30.8 0.0 2.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 mTERF LPD39 PF18858.1 GAX22487.1 - 0.068 13.2 3.1 0.36 10.9 0.2 2.3 1 1 1 2 2 2 0 Large polyvalent protein associated domain 39 Na_H_Exchanger PF00999.21 GAX22488.1 - 1.4e-46 159.1 26.2 6.6e-38 130.5 17.3 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Cation_ATPase_C PF00689.21 GAX22489.1 - 7.8e-07 29.0 8.3 1.3e-06 28.2 0.6 3.4 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAX22489.1 - 0.016 14.8 0.9 0.051 13.1 0.0 2.2 2 0 0 2 2 2 0 E1-E2 ATPase PI-PLC-X PF00388.19 GAX22489.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain TraG_N PF07916.11 GAX22489.1 - 0.48 9.2 5.2 3.1 6.5 0.0 2.6 2 0 0 2 2 2 0 TraG-like protein, N-terminal region EMP70 PF02990.16 GAX22489.1 - 0.67 8.5 3.5 0.89 8.1 0.4 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 FA_desaturase PF00487.24 GAX22489.1 - 1.5 8.6 8.2 0.6 9.9 2.2 2.9 3 0 0 3 3 3 0 Fatty acid desaturase Peptidase_M43 PF05572.13 GAX22491.1 - 2.9e-13 50.0 0.0 4.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX22491.1 - 0.00067 20.2 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX22491.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX22491.1 - 0.0019 18.2 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX22491.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 GAX22491.1 - 0.028 14.6 0.0 0.054 13.6 0.0 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 GAX22491.1 - 0.036 13.3 0.1 0.06 12.5 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M43 PF05572.13 GAX22492.1 - 7.6e-13 48.6 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX22492.1 - 0.0016 19.0 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX22492.1 - 0.0024 18.0 0.1 0.0045 17.1 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX22492.1 - 0.0085 15.7 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 GAX22492.1 - 0.02 15.0 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_2 PF13574.6 GAX22492.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 GAX22492.1 - 0.069 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 GAX22492.1 - 0.077 12.8 0.7 0.13 12.1 0.7 1.4 1 1 0 1 1 1 0 Matrixin UcrQ PF02939.16 GAX22493.1 - 0.0025 17.7 0.2 0.004 17.0 0.2 1.3 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 GAX22493.1 - 0.0047 17.3 0.1 0.0065 16.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 FA_hydroxylase PF04116.13 GAX22494.1 - 3.6e-17 62.9 19.0 5e-17 62.5 16.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TrbC PF04956.13 GAX22494.1 - 0.068 13.4 0.4 0.068 13.4 0.4 2.1 3 0 0 3 3 3 0 TrbC/VIRB2 family HemY_N PF07219.13 GAX22494.1 - 0.078 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Cytotoxic PF09000.10 GAX22494.1 - 0.086 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytotoxic ORC2 PF04084.14 GAX22495.1 - 5.5e-49 166.9 0.1 7.9e-49 166.3 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MBD PF01429.19 GAX22495.1 - 0.07 12.8 0.1 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Methyl-CpG binding domain AdoMet_MTase PF07757.13 GAX22496.1 - 0.0031 17.8 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase OTU PF02338.19 GAX22496.1 - 0.049 14.1 0.0 0.057 13.9 0.0 1.1 1 0 0 1 1 1 0 OTU-like cysteine protease Prenyltrans PF00432.21 GAX22497.1 - 1.5e-51 171.8 16.1 6e-12 45.1 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAX22497.1 - 0.00049 19.3 0.0 0.0023 17.1 0.0 2.0 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain ketoacyl-synt PF00109.26 GAX22498.1 - 1.7e-55 188.4 0.9 2.7e-55 187.7 0.9 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAX22498.1 - 5.3e-32 110.3 1.6 1.3e-31 109.1 1.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAX22498.1 - 2.3e-05 23.9 1.8 4.2e-05 23.1 1.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAX22498.1 - 0.043 13.7 3.4 1.7 8.6 0.4 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CitMHS PF03600.16 GAX22499.1 - 5.9e-30 104.5 13.5 6.4e-30 104.4 12.6 1.5 1 1 0 1 1 1 1 Citrate transporter CBS PF00571.28 GAX22499.1 - 1.6e-10 41.3 0.1 0.00018 21.9 0.0 2.9 2 0 0 2 2 2 2 CBS domain PseudoU_synth_2 PF00849.22 GAX22501.1 - 4.9e-25 88.5 0.0 7.7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase CPSase_L_D2 PF02786.17 GAX22502.1 - 1.4e-105 351.4 0.4 6.2e-79 264.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAX22502.1 - 4.1e-49 165.6 0.0 9.1e-49 164.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAX22502.1 - 1.6e-42 145.4 0.0 1.1e-41 142.7 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 GAX22502.1 - 1.4e-38 131.9 0.0 3.6e-38 130.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 GAX22502.1 - 2.1e-14 53.5 0.5 3.2e-08 33.3 0.2 3.2 3 0 0 3 3 3 2 ATP-grasp domain MGS PF02142.22 GAX22502.1 - 2e-13 50.3 0.1 4.7e-12 45.9 0.0 3.2 3 0 0 3 3 3 1 MGS-like domain Dala_Dala_lig_C PF07478.13 GAX22502.1 - 5.3e-12 45.7 0.3 3.9e-05 23.3 0.2 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAX22502.1 - 1.4e-11 44.2 0.1 3.6e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 GAX22502.1 - 1.9e-05 24.5 0.1 0.00093 19.0 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_5 PF13549.6 GAX22502.1 - 0.00039 20.0 0.0 0.23 10.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 GAX22502.1 - 0.017 15.2 0.2 2.2 8.3 0.0 2.9 3 0 0 3 3 3 0 ATP-grasp domain RimK PF08443.11 GAX22502.1 - 0.036 13.7 0.0 0.83 9.2 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GARS_A PF01071.19 GAX22502.1 - 0.047 13.5 0.4 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-synt_Eps PF04627.13 GAX22503.1 - 4.4e-15 55.4 1.9 5.2e-15 55.1 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Exo_endo_phos PF03372.23 GAX22504.1 - 9.8e-06 25.2 0.0 4.8e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 GAX22505.1 - 1.6e-30 106.2 0.0 2.9e-29 102.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Corona_I PF03187.14 GAX22505.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Corona nucleocapsid I protein EGL-1 PF11430.8 GAX22505.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 Methyltransf_16 PF10294.9 GAX22506.1 - 1.1e-12 48.0 0.0 4.7e-12 46.0 0.0 2.0 1 1 0 2 2 2 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAX22506.1 - 4.1e-05 24.3 0.0 0.0001 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22506.1 - 0.00031 20.6 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX22506.1 - 0.00036 21.2 0.0 0.001 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22506.1 - 0.028 15.0 0.0 0.084 13.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF1741 PF08427.10 GAX22507.1 - 0.012 15.3 1.6 0.2 11.3 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1741) AKAP7_NLS PF10469.9 GAX22507.1 - 0.12 12.3 2.6 0.12 12.3 0.4 2.1 2 0 0 2 2 2 0 AKAP7 2'5' RNA ligase-like domain RmuC PF02646.16 GAX22507.1 - 0.82 8.7 8.5 0.11 11.6 0.3 3.4 4 0 0 4 4 4 0 RmuC family PQQ_2 PF13360.6 GAX22508.1 - 1.1e-05 25.1 0.0 0.12 11.9 0.2 2.5 2 1 0 2 2 2 2 PQQ-like domain Pfk_N PF18468.1 GAX22508.1 - 0.053 13.9 0.1 4 7.9 0.0 2.4 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast PD40 PF07676.12 GAX22508.1 - 0.056 13.4 0.5 7.3 6.7 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Peptidase_S8 PF00082.22 GAX22510.1 - 1.2e-74 251.3 0.0 2.2e-74 250.4 0.0 1.4 1 1 0 1 1 1 1 Subtilase family TPPII PF12580.8 GAX22510.1 - 7.1e-50 169.1 0.0 1.1e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II TPPII_N PF12583.8 GAX22510.1 - 0.097 13.3 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Rieske_3 PF18465.1 GAX22510.1 - 0.13 12.6 0.0 6 7.2 0.0 2.5 2 0 0 2 2 2 0 Rieske 3Fe-4S Peptidase_S8 PF00082.22 GAX22511.1 - 3.7e-31 108.5 5.3 6e-31 107.8 5.3 1.3 1 0 0 1 1 1 1 Subtilase family Dickkopf_N PF04706.12 GAX22511.1 - 0.015 15.8 1.9 0.015 15.8 1.9 3.1 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Toxin_12 PF07740.12 GAX22511.1 - 0.043 14.5 5.9 0.043 14.5 5.9 2.4 2 0 0 2 2 2 0 Ion channel inhibitory toxin Toxin_18 PF08087.11 GAX22511.1 - 1.2 9.2 10.2 1 9.4 1.6 2.9 2 0 0 2 2 2 0 Conotoxin O-superfamily Conotoxin_I2 PF17557.2 GAX22511.1 - 5.7 7.1 20.1 7.4 6.8 6.6 2.8 2 0 0 2 2 2 0 I2-superfamily conotoxins TRAPPC-Trs85 PF12739.7 GAX22513.1 - 3.8e-61 207.3 10.2 4.6e-60 203.7 8.8 2.7 2 1 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 GAX22513.1 - 0.0038 16.7 4.6 0.026 13.9 0.2 2.5 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TRAPPC9-Trs120 PF08626.11 GAX22513.1 - 0.0062 14.0 0.0 0.014 12.8 0.0 1.5 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 GAX22513.1 - 5.8 7.3 10.6 9.7 6.6 2.4 3.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Nucleopor_Nup85 PF07575.13 GAX22514.1 - 1.1e-14 54.0 1.6 1.2e-08 34.1 0.0 2.7 3 0 0 3 3 3 2 Nup85 Nucleoporin Asp_Arg_Hydrox PF05118.15 GAX22515.1 - 7.6e-44 149.3 0.8 1e-43 148.9 0.8 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase DUF739 PF05339.11 GAX22515.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF739) Peptidase_S8 PF00082.22 GAX22516.1 - 2.3e-30 105.9 6.2 4.1e-30 105.1 6.2 1.4 1 0 0 1 1 1 1 Subtilase family PT PF04886.12 GAX22516.1 - 3.5e-05 23.2 77.8 0.28 10.8 27.0 5.6 1 1 2 3 3 3 2 PT repeat Inhibitor_I9 PF05922.16 GAX22516.1 - 9.8e-05 23.0 0.2 0.00019 22.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Adhesin_P1_N PF18652.1 GAX22516.1 - 0.072 13.1 0.6 0.14 12.2 0.6 1.4 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain Toxin_12 PF07740.12 GAX22516.1 - 0.32 11.7 8.0 0.74 10.6 8.0 1.6 1 0 0 1 1 1 0 Ion channel inhibitory toxin S4 PF01479.25 GAX22517.1 - 2.2e-13 49.7 0.8 3.9e-13 48.9 0.8 1.4 1 0 0 1 1 1 1 S4 domain DUF1648 PF07853.11 GAX22518.1 - 0.036 13.7 0.1 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) TIR-like PF10137.9 GAX22521.1 - 0.041 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain DUF3398 PF11878.8 GAX22521.1 - 0.2 12.1 0.3 0.41 11.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) Fasciclin PF02469.22 GAX22522.1 - 7.1e-14 52.1 0.1 5.7e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain NodZ PF05830.11 GAX22524.1 - 1.4e-06 27.4 0.0 3.8e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Nodulation protein Z (NodZ) TB2_DP1_HVA22 PF03134.19 GAX22525.1 - 0.015 15.2 1.7 0.015 15.2 1.7 4.7 4 1 0 4 4 4 0 TB2/DP1, HVA22 family PI3_PI4_kinase PF00454.27 GAX22526.1 - 1.5e-30 106.9 0.0 5.9e-28 98.4 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 GAX22526.1 - 0.00014 22.3 0.0 0.00038 20.9 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4135 PF13575.6 GAX22526.1 - 0.036 13.4 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Exonuc_VII_L PF02601.15 GAX22527.1 - 0.0018 17.9 7.1 0.002 17.8 7.1 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 GAX22527.1 - 0.016 15.2 0.6 0.016 15.2 0.6 3.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding RE_TdeIII PF09520.10 GAX22527.1 - 0.018 14.7 2.7 0.027 14.1 2.7 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Yop-YscD_cpl PF16697.5 GAX22527.1 - 0.029 14.7 0.7 0.082 13.2 0.3 2.0 1 1 1 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain RPW8 PF05659.11 GAX22527.1 - 0.074 12.7 6.2 0.08 12.6 5.2 1.6 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Leu_zip PF15294.6 GAX22527.1 - 0.3 10.6 21.8 0.58 9.6 5.7 2.1 1 1 1 2 2 2 0 Leucine zipper Pinin_SDK_N PF04697.13 GAX22527.1 - 1.5 9.5 6.1 0.33 11.6 1.3 2.2 2 0 0 2 2 2 0 pinin/SDK conserved region Geminin PF07412.12 GAX22527.1 - 1.7 8.4 22.4 1.8 8.3 3.8 3.3 1 1 1 3 3 3 0 Geminin FAM76 PF16046.5 GAX22527.1 - 2.1 7.6 19.9 0.12 11.7 10.9 2.0 1 1 1 2 2 2 0 FAM76 protein Cytochrom_C552 PF02335.15 GAX22527.1 - 2.3 7.0 12.3 0.17 10.8 4.6 2.0 1 1 1 2 2 2 0 Cytochrome c552 MRPL52 PF18699.1 GAX22527.1 - 9.8 6.4 10.8 0.96 9.7 2.5 2.8 2 1 0 2 2 2 0 Mitoribosomal protein mL52 DUF4558 PF15104.6 GAX22528.1 - 0.027 14.5 0.3 0.19 11.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) HEAT PF02985.22 GAX22529.1 - 3.6e-30 101.4 23.4 0.0022 18.1 0.0 12.0 12 0 0 12 12 12 8 HEAT repeat HEAT_2 PF13646.6 GAX22529.1 - 5.2e-27 94.1 10.9 7.9e-05 23.0 0.0 7.4 4 2 2 7 7 7 6 HEAT repeats Cnd1 PF12717.7 GAX22529.1 - 5.8e-14 52.4 0.6 0.0077 16.3 0.0 5.2 3 1 4 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX22529.1 - 8.7e-10 38.9 16.1 0.00015 22.2 0.0 8.1 8 1 0 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.20 GAX22529.1 - 2.4e-07 29.7 0.0 0.036 12.6 0.0 4.0 2 1 2 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 GAX22529.1 - 0.00075 19.1 0.2 4.5 6.8 0.0 3.4 3 1 1 4 4 4 2 CLASP N terminal IFRD PF05004.13 GAX22529.1 - 0.0029 16.8 4.1 2.4 7.2 0.4 4.9 4 2 1 5 5 5 1 Interferon-related developmental regulator (IFRD) V-ATPase_H_N PF03224.14 GAX22529.1 - 0.0036 16.7 0.1 2.6 7.3 0.0 2.4 2 1 0 2 2 2 2 V-ATPase subunit H Gcn1_N PF12074.8 GAX22529.1 - 0.051 12.9 1.1 3.3 6.9 0.0 3.4 5 0 0 5 5 5 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DRIM PF07539.12 GAX22529.1 - 0.18 10.1 0.5 3.1 6.0 0.0 2.7 3 0 0 3 3 3 0 Down-regulated in metastasis HEAT_PBS PF03130.16 GAX22529.1 - 5.5 8.0 12.1 32 5.6 0.1 6.0 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat ECF_trnsprt PF12822.7 GAX22530.1 - 4.2 7.4 13.3 0.29 11.2 4.8 2.6 2 1 0 2 2 2 0 ECF transporter, substrate-specific component Myosin_head PF00063.21 GAX22532.1 - 6.3e-181 603.0 0.1 3.8e-180 600.5 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_22 PF13401.6 GAX22532.1 - 0.012 15.9 1.3 0.096 13.0 0.0 3.2 4 0 0 4 4 4 0 AAA domain Myosin_N PF02736.19 GAX22532.1 - 0.013 15.3 1.1 0.18 11.7 0.0 3.0 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 GAX22532.1 - 0.056 13.8 0.0 0.056 13.8 0.0 3.5 2 1 1 3 3 3 0 AAA ATPase domain Hpr_kinase_C PF07475.12 GAX22532.1 - 0.19 11.2 0.4 13 5.2 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IQ PF00612.27 GAX22532.1 - 0.84 9.6 29.6 1.2 9.1 0.9 5.7 5 0 0 5 5 5 0 IQ calmodulin-binding motif ABC_tran PF00005.27 GAX22532.1 - 3.9 8.0 0.0 3.9 8.0 0.0 3.3 3 1 1 4 4 4 0 ABC transporter DUF4383 PF14325.6 GAX22533.1 - 0.0067 16.7 8.0 0.0092 16.3 8.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) DUF4064 PF13273.6 GAX22533.1 - 0.015 15.5 4.6 0.57 10.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Got1 PF04178.12 GAX22533.1 - 0.2 12.1 10.4 0.3 11.5 10.4 1.2 1 0 0 1 1 1 0 Got1/Sft2-like family DSPc PF00782.20 GAX22534.1 - 2.1e-20 72.9 0.0 2.8e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAX22534.1 - 2.8e-06 27.5 0.0 3.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAX22534.1 - 0.0042 16.7 0.1 0.007 16.0 0.1 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 GAX22534.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Pkinase PF00069.25 GAX22535.1 - 2.3e-58 197.6 0.0 3.7e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22535.1 - 3.6e-41 141.2 0.0 5.4e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 GAX22535.1 - 5.3e-14 52.2 0.4 1.2e-13 51.1 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 GAX22535.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX22535.1 - 0.049 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family HBM PF16591.5 GAX22535.1 - 0.071 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Helical bimodular sensor domain MFS_1 PF07690.16 GAX22536.1 - 1e-12 47.7 34.1 1e-12 47.7 34.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CxC6 PF18721.1 GAX22537.1 - 0.0031 17.8 5.1 0.0063 16.8 5.1 1.5 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases HD_3 PF13023.6 GAX22538.1 - 0.09 12.7 0.1 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 HD domain VGCC_beta4Aa_N PF12052.8 GAX22538.1 - 0.61 10.2 3.9 0.28 11.3 0.7 2.0 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal GST_C PF00043.25 GAX22540.1 - 3.7e-09 36.7 0.0 5.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX22540.1 - 5.2e-09 36.2 0.0 7.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAX22540.1 - 2.3e-05 24.7 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX22540.1 - 2.5e-05 24.2 0.0 4.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX22540.1 - 0.012 16.0 0.1 0.038 14.4 0.0 1.8 2 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain XPG_I PF00867.18 GAX22541.1 - 2.4e-11 43.8 0.0 5.6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 GAX22541.1 - 0.0008 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 GAX22541.1 - 0.002 18.6 0.0 0.35 11.3 0.0 2.6 2 0 0 2 2 2 2 XPG N-terminal domain XRN_N PF03159.18 GAX22541.1 - 0.015 14.7 0.9 0.038 13.4 0.2 1.9 2 1 1 3 3 3 0 XRN 5'-3' exonuclease N-terminus Ribosomal_L21e PF01157.18 GAX22542.1 - 8.6e-44 147.5 5.6 1.6e-43 146.6 4.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e HAS-barrel PF09378.10 GAX22542.1 - 0.006 16.7 0.0 0.022 14.9 0.0 2.0 1 1 1 2 2 2 1 HAS barrel domain ZapB PF06005.12 GAX22542.1 - 0.047 14.1 0.6 0.076 13.5 0.6 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF2846 PF11008.8 GAX22542.1 - 0.049 13.7 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Ank_2 PF12796.7 GAX22543.1 - 7.5e-10 39.3 0.1 1.8e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX22543.1 - 6.5e-07 29.2 0.1 0.0031 17.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAX22543.1 - 2.9e-06 27.7 0.1 9.3e-05 22.9 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX22543.1 - 8e-06 26.0 0.3 6.6e-05 23.1 0.1 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX22543.1 - 2.4e-05 24.6 0.4 0.0018 18.6 0.1 3.5 4 0 0 4 4 4 1 Ankyrin repeat CSN7a_helixI PF18392.1 GAX22543.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Methyltransf_4 PF02390.17 GAX22543.1 - 0.083 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase VASt PF16016.5 GAX22544.1 - 8.9e-26 91.1 0.2 2.8e-25 89.5 0.1 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAX22544.1 - 3.7e-09 36.4 0.0 0.00037 20.3 0.0 2.6 2 0 0 2 2 2 2 GRAM domain PBP_N PF17093.5 GAX22546.1 - 0.072 13.3 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF350 PF03994.14 GAX22546.1 - 0.5 10.6 3.4 26 5.1 0.0 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) RNase_3_N PF18497.1 GAX22547.1 - 0.11 12.8 0.8 3.7 7.8 0.0 2.7 2 1 0 2 2 2 0 Ribonuclease III N-terminal domain Peptidase_M3 PF01432.20 GAX22548.1 - 2.6e-42 145.7 0.0 3.7e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Clathrin PF00637.20 GAX22548.1 - 0.044 13.7 0.1 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS VASt PF16016.5 GAX22549.1 - 1.3e-21 77.6 0.3 2.2e-21 76.9 0.3 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAX22549.1 - 2.8e-06 27.2 0.1 6.5e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 GRAM domain PPR PF01535.20 GAX22550.1 - 1.2e-46 153.7 19.1 9.5e-05 22.4 0.0 16.6 17 0 0 17 17 17 11 PPR repeat PPR_2 PF13041.6 GAX22550.1 - 3.7e-45 151.9 14.2 7.7e-08 32.4 0.1 14.0 9 4 6 15 15 15 10 PPR repeat family PPR_3 PF13812.6 GAX22550.1 - 1.3e-42 143.7 0.0 2.9e-11 43.3 0.0 10.2 6 3 3 10 10 10 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX22550.1 - 1.3e-30 106.4 5.8 1.8e-07 30.8 0.0 6.3 4 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAX22550.1 - 1e-25 89.1 16.9 9.2e-05 22.1 0.0 12.0 14 0 0 14 14 14 5 PPR repeat Smr PF01713.21 GAX22550.1 - 1.9e-06 28.1 0.1 6.7e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 Smr domain ATP13 PF12921.7 GAX22550.1 - 1.5e-05 24.8 0.0 0.22 11.4 0.0 5.7 6 1 0 6 6 6 1 Mitochondrial ATPase expression TPR_5 PF12688.7 GAX22550.1 - 3.5e-05 24.0 1.3 0.00087 19.5 0.0 3.7 3 1 1 4 4 4 1 Tetratrico peptide repeat TPR_19 PF14559.6 GAX22550.1 - 0.00033 21.1 8.2 9.6 6.8 0.2 7.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX22550.1 - 0.00034 20.3 2.4 6.7 6.7 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat Clathrin PF00637.20 GAX22550.1 - 0.00041 20.3 1.2 39 4.1 0.0 6.2 6 0 0 6 6 6 0 Region in Clathrin and VPS TPR_14 PF13428.6 GAX22550.1 - 0.00097 19.8 18.7 27 5.9 0.1 9.7 12 1 0 12 12 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX22550.1 - 0.0017 18.6 5.7 2.7 8.3 0.5 5.7 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAX22550.1 - 0.094 12.9 10.7 1.1e+02 3.3 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX22550.1 - 0.11 13.1 2.7 32 5.3 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX22550.1 - 0.14 12.5 11.6 28 5.1 0.0 6.6 8 1 2 10 10 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX22550.1 - 2.3 9.0 10.9 42 5.1 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat Pet100 PF09803.9 GAX22551.1 - 6 7.5 6.1 6.3 7.4 2.9 2.7 2 0 0 2 2 2 0 Pet100 Lipocalin_2 PF08212.12 GAX22552.1 - 6.4e-21 74.8 0.0 7.7e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain XH PF03469.14 GAX22552.1 - 0.057 13.3 0.1 0.56 10.1 0.0 2.3 3 0 0 3 3 3 0 XH domain DUF308 PF03729.13 GAX22553.1 - 3.6e-07 30.4 10.5 0.0052 17.1 0.2 3.3 2 1 1 3 3 3 2 Short repeat of unknown function (DUF308) DUF3098 PF11297.8 GAX22553.1 - 0.073 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DUF2207 PF09972.9 GAX22553.1 - 0.086 11.6 0.2 0.11 11.2 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PAP_fibrillin PF04755.12 GAX22554.1 - 9.8e-09 35.4 0.1 6.2e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 PAP_fibrillin ParE_toxin PF05016.15 GAX22554.1 - 0.027 15.1 0.0 0.15 12.7 0.0 2.2 3 0 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE Linker_histone PF00538.19 GAX22555.1 - 2.3e-14 53.5 0.5 2.3e-14 53.5 0.5 1.9 1 1 1 2 2 2 1 linker histone H1 and H5 family Recombinase PF07508.13 GAX22555.1 - 0.16 12.4 6.6 0.46 10.9 6.6 1.9 1 1 0 1 1 1 0 Recombinase vMSA PF00695.19 GAX22555.1 - 1.1 8.3 0.0 1.1 8.3 0.0 1.9 1 1 1 2 2 2 0 Major surface antigen from hepadnavirus KAR9 PF08580.10 GAX22555.1 - 2.8 6.4 17.2 3.1 6.2 17.2 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Dicty_REP PF05086.12 GAX22555.1 - 5.5 4.8 11.8 6.1 4.7 11.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF908 PF06012.12 GAX22555.1 - 8.8 5.6 12.9 12 5.2 12.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Histone PF00125.24 GAX22556.1 - 2.8e-19 69.8 0.4 3.6e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX22556.1 - 0.00095 19.4 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAX22556.1 - 0.0039 17.6 0.0 0.0068 16.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 GAX22556.1 - 0.0062 16.6 0.1 0.0069 16.4 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein Bt_P21 PF05560.11 GAX22556.1 - 0.046 13.3 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone_H2A_C PF16211.5 GAX22557.1 - 4.2e-20 71.2 1.9 8.8e-20 70.2 1.9 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAX22557.1 - 6.2e-15 55.7 0.0 7.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX22557.1 - 0.00038 20.7 0.0 0.00063 20.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Adap_comp_sub PF00928.21 GAX22558.1 - 2.9e-90 302.2 0.0 3.6e-90 301.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAX22558.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 GAX22558.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Na_H_Exchanger PF00999.21 GAX22559.1 - 2.1e-60 204.5 47.8 4.1e-60 203.6 47.8 1.4 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 GAX22559.1 - 7.6e-19 68.1 0.1 1.9e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain AdoHcyase_NAD PF00670.21 GAX22559.1 - 0.0084 16.2 0.2 0.016 15.3 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pirin PF02678.16 GAX22560.1 - 4.7e-32 110.2 0.9 1.8e-31 108.3 0.5 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 GAX22560.1 - 1.1e-22 80.3 0.0 6.4e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain ELMO_CED12 PF04727.13 GAX22561.1 - 0.15 12.2 1.6 0.44 10.6 0.8 2.0 1 1 1 2 2 2 0 ELMO/CED-12 family Histone_H2A_C PF16211.5 GAX22562.1 - 4.2e-20 71.2 1.9 8.8e-20 70.2 1.9 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAX22562.1 - 6.2e-15 55.7 0.0 7.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX22562.1 - 0.00038 20.7 0.0 0.00063 20.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX22563.1 - 6.9e-54 181.7 1.0 7.7e-54 181.6 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GAX22563.1 - 0.00011 22.7 1.1 0.00014 22.5 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GAX22563.1 - 0.00072 19.6 0.3 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX22563.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAX22563.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAX22563.1 - 0.045 13.8 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 GAX22565.1 - 6.8e-62 209.2 0.0 1.1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22565.1 - 9.3e-29 100.5 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX22565.1 - 9.7e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 GAX22565.1 - 0.01 16.5 0.2 0.01 16.5 0.2 2.4 2 1 0 2 2 2 0 Protein kinase C terminal domain APH PF01636.23 GAX22565.1 - 0.018 15.0 0.1 0.058 13.3 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX22565.1 - 0.2 10.4 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FAD-oxidase_C PF02913.19 GAX22566.1 - 1.9e-45 155.4 0.0 2.4e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAX22566.1 - 3.9e-36 123.8 0.9 8.3e-36 122.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain P3A PF08727.11 GAX22566.1 - 0.059 12.8 0.1 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Poliovirus 3A protein like Complex1_LYR PF05347.15 GAX22567.1 - 0.002 18.2 0.5 0.03 14.4 0.1 2.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) ASXH PF13919.6 GAX22567.1 - 0.036 14.1 0.3 0.1 12.6 0.2 1.8 1 1 0 1 1 1 0 Asx homology domain Lipocalin_2 PF08212.12 GAX22568.1 - 0.00056 19.9 0.0 0.014 15.3 0.0 2.3 1 1 0 1 1 1 1 Lipocalin-like domain Sulfotransfer_3 PF13469.6 GAX22569.1 - 1e-10 42.4 0.0 1.5e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 GAX22569.1 - 1.8e-09 37.8 1.1 7.2e-05 22.7 0.4 3.0 2 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_1 PF00685.27 GAX22569.1 - 6.9e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain WD40 PF00400.32 GAX22572.1 - 1.7e-47 158.4 27.2 5.3e-06 27.1 0.1 11.7 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp13 PF08625.11 GAX22572.1 - 1.2e-36 125.8 0.1 1.8e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 GAX22572.1 - 1.3e-14 54.2 6.5 0.0087 16.3 0.3 6.6 5 2 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX22572.1 - 2.1e-06 27.3 0.0 0.69 9.2 0.0 4.9 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 GAX22572.1 - 0.00015 20.6 7.2 0.36 9.4 0.0 5.5 5 3 2 7 7 7 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX22572.1 - 0.0053 15.8 0.3 7.9 5.3 0.0 4.6 4 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Mcl1_mid PF12341.8 GAX22572.1 - 0.085 12.2 0.1 14 4.9 0.0 2.4 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region SHMT PF00464.19 GAX22572.1 - 0.087 11.4 0.0 11 4.4 0.0 2.6 2 1 1 3 3 3 0 Serine hydroxymethyltransferase Cpn10 PF00166.21 GAX22573.1 - 4.3e-10 39.5 0.0 6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit BTB_2 PF02214.22 GAX22574.1 - 3.8e-16 59.2 0.0 7.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX22574.1 - 0.0069 16.5 0.0 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Spc7 PF08317.11 GAX22574.1 - 0.012 14.5 0.5 0.016 14.1 0.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GTP_EFTU PF00009.27 GAX22575.1 - 3.5e-37 127.8 0.0 5.9e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 GAX22575.1 - 3.8e-25 88.8 5.4 3.8e-25 88.8 5.4 1.9 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 GAX22575.1 - 3.8e-23 81.6 0.0 1.2e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 GAX22575.1 - 5e-21 74.5 0.0 1.4e-20 73.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX22575.1 - 2.1e-07 31.2 0.0 4.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAX22575.1 - 7.7e-06 25.9 0.0 2.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAX22575.1 - 0.00043 20.3 0.0 0.00084 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAX22575.1 - 0.14 11.6 0.0 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit TRAM_LAG1_CLN8 PF03798.16 GAX22576.1 - 1.7e-15 57.3 10.7 3e-15 56.5 10.7 1.3 1 0 0 1 1 1 1 TLC domain ATP-grasp_2 PF08442.10 GAX22577.1 - 8.4e-62 208.3 0.1 1.3e-61 207.7 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 GAX22577.1 - 1e-22 80.6 0.6 1.6e-22 80.0 0.6 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 GAX22577.1 - 1e-06 28.4 0.1 2.6e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAX22577.1 - 0.0093 15.7 0.9 0.071 12.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 GAX22577.1 - 0.051 13.4 0.2 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain FHA PF00498.26 GAX22578.1 - 2.2e-08 34.3 0.0 3.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAX22578.1 - 3.7e-05 24.0 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ax_dynein_light PF10211.9 GAX22578.1 - 0.033 14.1 0.5 0.046 13.7 0.5 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF778 PF05608.12 GAX22579.1 - 1.5e-30 106.9 3.7 1.5e-15 58.0 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) MatE PF01554.18 GAX22580.1 - 1.4e-31 109.3 19.9 3.5e-17 62.5 5.1 2.2 2 0 0 2 2 2 2 MatE Sulfate_transp PF00916.20 GAX22581.1 - 7.5e-27 94.1 14.5 9.8e-26 90.4 14.5 2.1 1 1 0 1 1 1 1 Sulfate permease family NDUF_B12 PF08122.12 GAX22581.1 - 3.6 7.7 5.4 30 4.8 0.7 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Lactamase_B_2 PF12706.7 GAX22582.1 - 8.8e-13 48.2 0.1 9.6e-05 22.0 0.0 3.2 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX22582.1 - 6.2e-11 42.7 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 GAX22582.1 - 1.6e-05 24.5 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Pkinase PF00069.25 GAX22583.1 - 7.2e-51 173.1 0.0 9.4e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22583.1 - 1.2e-22 80.5 0.4 3e-22 79.2 0.4 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX22583.1 - 2.1e-05 24.0 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAX22583.1 - 0.026 14.5 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAX22583.1 - 0.048 13.3 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family FeoB_Cyto PF17910.1 GAX22583.1 - 0.065 13.8 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 FeoB cytosolic helical domain DUF1230 PF06799.11 GAX22584.1 - 4.8e-47 159.7 0.1 6.5e-47 159.2 0.1 1.2 1 0 0 1 1 1 1 Conserved in the green lineage and diatoms 27 MBOAT PF03062.19 GAX22584.1 - 0.049 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family FKBP_C PF00254.28 GAX22585.1 - 4.1e-23 81.5 0.0 9.3e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 GAX22585.1 - 3.9e-06 27.7 0.0 5.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Peptidase_S28 PF05577.12 GAX22586.1 - 7.6e-43 146.9 0.2 1.2e-41 143.0 0.2 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Ank_3 PF13606.6 GAX22587.1 - 0.68 10.7 9.7 32 5.6 0.1 5.0 6 0 0 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 GAX22589.1 - 0.045 14.4 0.3 0.25 12.0 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX22589.1 - 0.8 10.5 2.8 74 4.4 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 GAX22590.1 - 0.032 14.5 0.0 5.2 7.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Nop14 PF04147.12 GAX22590.1 - 0.55 8.4 7.7 0.83 7.8 7.7 1.2 1 0 0 1 1 1 0 Nop14-like family MMR_HSR1 PF01926.23 GAX22591.1 - 2.4e-16 59.8 0.0 4.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX22591.1 - 1.9e-08 34.0 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX22591.1 - 2e-07 31.1 0.0 0.00025 21.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAX22591.1 - 1.9e-06 27.6 0.2 2.1e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GAX22591.1 - 0.00075 19.7 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAX22591.1 - 0.0089 16.1 1.3 0.26 11.3 0.2 2.6 2 1 1 3 3 3 1 Dynamin family SRPRB PF09439.10 GAX22591.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 GAX22591.1 - 0.053 13.1 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Ras family DNA_pol_phi PF04931.13 GAX22591.1 - 0.098 10.7 11.6 0.13 10.4 11.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 GAX22591.1 - 1.5 8.0 9.1 2.4 7.4 9.1 1.2 1 0 0 1 1 1 0 BUD22 Band_7 PF01145.25 GAX22592.1 - 1.1e-25 90.7 3.8 1.5e-25 90.3 3.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAX22592.1 - 0.0016 18.2 0.3 0.0026 17.5 0.3 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Lipoprotein_16 PF03923.13 GAX22592.1 - 0.044 13.4 1.7 0.15 11.7 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized lipoprotein Macoilin PF09726.9 GAX22595.1 - 3 6.3 24.9 3.5 6.1 24.9 1.0 1 0 0 1 1 1 0 Macoilin family ALMT PF11744.8 GAX22595.1 - 3.5 6.3 16.5 4.5 6.0 16.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter WDCP PF15390.6 GAX22595.1 - 3.5 5.9 19.3 4.4 5.6 19.3 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family 6PGD PF00393.19 GAX22597.1 - 2.9e-121 404.3 0.0 3.6e-121 404.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAX22597.1 - 2.1e-44 151.5 0.0 3.3e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 GAX22597.1 - 0.067 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 GAX22597.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TIC20 PF16166.5 GAX22598.1 - 2.1e-17 63.5 0.1 3.6e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like EF-hand_7 PF13499.6 GAX22598.1 - 1e-14 54.7 2.2 9.4e-10 38.8 0.4 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX22598.1 - 3.7e-12 44.9 0.2 2e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 GAX22598.1 - 4.3e-11 41.8 1.5 3.9e-07 29.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX22598.1 - 5e-10 38.5 0.3 1.8e-05 24.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAX22598.1 - 1.9e-08 34.0 0.9 5.9e-06 26.0 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 GAX22598.1 - 0.00044 20.5 0.0 0.00088 19.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GAX22598.1 - 0.0039 17.5 0.0 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region QCR10 PF09796.9 GAX22598.1 - 0.031 14.3 4.1 0.14 12.2 0.6 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4407 PF14362.6 GAX22598.1 - 0.12 11.7 5.1 0.22 10.8 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hpt PF01627.23 GAX22598.1 - 0.44 10.9 6.7 0.46 10.8 5.0 2.0 1 1 1 2 2 2 0 Hpt domain DUF4140 PF13600.6 GAX22598.1 - 3.3 8.2 5.8 1 9.9 0.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YejG PF13989.6 GAX22599.1 - 0.36 11.3 3.2 0.71 10.3 0.9 2.2 1 1 1 2 2 2 0 YejG-like protein Prefoldin PF02996.17 GAX22599.1 - 0.57 10.1 10.9 0.052 13.5 4.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit Atg14 PF10186.9 GAX22599.1 - 1.1 8.2 8.9 1.6 7.8 8.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Thioredoxin_4 PF13462.6 GAX22599.1 - 3.1 7.9 6.7 1.3 9.2 3.7 1.9 1 1 1 2 2 2 0 Thioredoxin Mis12 PF05859.12 GAX22599.1 - 6.7 6.8 14.7 1.5 8.9 9.2 2.5 2 1 0 2 2 2 0 Mis12 protein RRM_1 PF00076.22 GAX22600.1 - 1.7e-60 200.7 0.1 1.3e-20 72.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX22600.1 - 2.6e-11 43.5 0.0 0.001 19.2 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif DbpA PF03880.15 GAX22600.1 - 2e-06 27.7 0.0 0.43 10.6 0.0 3.5 3 0 0 3 3 3 2 DbpA RNA binding domain RRM_5 PF13893.6 GAX22600.1 - 9.4e-06 25.2 0.0 0.0008 19.0 0.0 3.0 2 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAX22600.1 - 0.0011 18.9 0.0 0.98 9.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 GAX22600.1 - 0.0019 18.2 0.3 0.88 9.7 0.1 3.4 3 1 0 3 3 3 1 Limkain b1 RRM_3 PF08777.11 GAX22600.1 - 0.0083 16.2 0.0 1.3 9.1 0.0 3.2 3 1 0 3 3 3 1 RNA binding motif ParA PF10609.9 GAX22601.1 - 4.8e-79 265.3 0.0 4.2e-72 242.6 0.3 2.0 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAX22601.1 - 4.2e-12 46.2 0.0 1.3e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX22601.1 - 5.3e-08 33.0 0.0 1.2e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAX22601.1 - 3.2e-06 26.6 3.9 0.0001 21.6 0.8 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 GAX22601.1 - 8.8e-06 25.2 0.4 4.8e-05 22.8 0.2 1.9 2 0 0 2 2 2 1 ATPase MipZ MeaB PF03308.16 GAX22601.1 - 1.8e-05 23.9 0.1 2.7e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 GAX22601.1 - 0.00022 21.1 1.2 0.16 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain VirC1 PF07015.11 GAX22601.1 - 0.00041 19.7 0.1 0.0026 17.1 0.1 2.0 2 0 0 2 2 2 1 VirC1 protein AAA_16 PF13191.6 GAX22601.1 - 0.00048 20.6 0.1 0.0011 19.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain CLP1_P PF16575.5 GAX22601.1 - 0.00048 20.0 0.1 0.0064 16.3 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 GAX22601.1 - 0.0006 19.7 0.1 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 GAX22601.1 - 0.00067 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAX22601.1 - 0.00078 18.7 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.20 GAX22601.1 - 0.0012 18.8 0.2 0.0022 17.9 0.2 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase SRP54 PF00448.22 GAX22601.1 - 0.0028 17.3 0.1 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 GAX22601.1 - 0.0069 16.3 0.4 0.016 15.2 0.2 1.7 2 0 0 2 2 2 1 NTPase Fer4_NifH PF00142.18 GAX22601.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NACHT PF05729.12 GAX22601.1 - 0.022 14.7 0.3 0.058 13.3 0.2 1.7 2 0 0 2 2 1 0 NACHT domain RNA_helicase PF00910.22 GAX22601.1 - 0.043 14.2 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 GAX22601.1 - 0.043 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAX22601.1 - 0.052 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 GAX22601.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Hpr_kinase_C PF07475.12 GAX22601.1 - 0.076 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain KTI12 PF08433.10 GAX22601.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DAP3 PF10236.9 GAX22601.1 - 0.086 12.0 0.3 0.15 11.2 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CBP_BcsQ PF06564.12 GAX22601.1 - 0.11 12.0 0.2 0.26 10.7 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MobB PF03205.14 GAX22601.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 GAX22601.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 GAX22601.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAX22601.1 - 0.19 11.0 0.2 0.65 9.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Tudor_3 PF18115.1 GAX22602.1 - 4.2e-11 42.5 0.1 6e-05 22.8 0.0 2.7 2 0 0 2 2 2 2 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 GAX22602.1 - 3.2e-07 30.7 0.8 0.036 14.5 0.1 3.4 3 0 0 3 3 3 2 Agenet domain TUDOR_5 PF18359.1 GAX22602.1 - 5.8e-06 25.9 0.1 0.083 12.6 0.0 3.3 3 0 0 3 3 3 2 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 GAX22602.1 - 0.00019 21.4 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 GAX22602.1 - 0.0071 16.0 0.0 0.31 10.8 0.0 2.7 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain DUF1325 PF07039.11 GAX22602.1 - 0.0077 16.3 0.0 0.86 9.7 0.0 2.5 2 0 0 2 2 2 1 SGF29 tudor-like domain LBR_tudor PF09465.10 GAX22602.1 - 0.063 13.1 0.2 13 5.7 0.0 2.9 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain TRAPPC9-Trs120 PF08626.11 GAX22603.1 - 7.3e-16 56.8 0.0 1e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Y_phosphatase3 PF13350.6 GAX22604.1 - 1.7e-42 146.0 0.1 2.9e-29 102.7 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAX22604.1 - 0.00036 20.2 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAX22604.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_L7Ae PF01248.26 GAX22604.1 - 0.15 11.9 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2_2 PF12756.7 GAX22605.1 - 0.045 14.1 0.8 1.4 9.3 0.3 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Trigger_N PF05697.13 GAX22606.1 - 0.0003 21.1 0.1 0.00049 20.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) Adap_comp_sub PF00928.21 GAX22607.1 - 3.6e-62 210.1 0.0 4.8e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family PCI PF01399.27 GAX22608.1 - 5.3e-14 52.6 0.1 1.4e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 PCI domain DUF1843 PF08898.10 GAX22608.1 - 1.6 9.3 8.8 3.7 8.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DDT PF02791.17 GAX22610.1 - 3.1e-14 53.0 0.1 9.4e-14 51.5 0.1 1.9 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 GAX22610.1 - 4.5e-09 36.7 0.1 4.5e-09 36.7 0.1 3.0 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF722 PF05263.11 GAX22610.1 - 0.3 11.3 7.2 14 5.9 3.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF722) AAA_15 PF13175.6 GAX22610.1 - 2.6 7.7 16.5 0.055 13.2 1.2 3.6 3 1 0 3 3 3 0 AAA ATPase domain Aldedh PF00171.22 GAX22611.1 - 1.2e-77 261.4 0.0 1.4e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Bestrophin PF01062.21 GAX22612.1 - 5.9e-28 98.1 3.4 8.3e-28 97.6 3.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FSH1 PF03959.13 GAX22613.1 - 5.2e-28 98.2 0.0 1.1e-27 97.1 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) RWD PF05773.22 GAX22613.1 - 2.3e-14 53.7 0.2 3.7e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 RWD domain MMR_HSR1 PF01926.23 GAX22613.1 - 1.1e-11 44.8 0.0 2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_C PF08438.10 GAX22613.1 - 3.2e-06 27.7 0.0 0.11 13.1 0.0 2.6 2 0 0 2 2 2 2 GTPase of unknown function C-terminal FeoB_N PF02421.18 GAX22613.1 - 0.0014 18.2 0.0 0.045 13.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Hydrolase_4 PF12146.8 GAX22613.1 - 0.0068 15.7 0.4 0.71 9.1 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAX22613.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase ATP_bind_1 PF03029.17 GAX22613.1 - 0.044 13.5 0.0 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 GAX22613.1 - 0.065 13.1 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 GAX22613.1 - 0.17 10.9 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mpv17_PMP22 PF04117.12 GAX22614.1 - 2.7e-10 40.3 0.9 5.9e-10 39.2 0.9 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Lactamase_B PF00753.27 GAX22615.1 - 0.0014 18.7 0.2 0.0014 18.7 0.2 1.8 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily FPRL1_inhibitor PF16104.5 GAX22615.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Formyl peptide receptor-like 1 inhibitory protein HTH_Tnp_Mu_1 PF02316.16 GAX22616.1 - 0.097 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain MFS_1 PF07690.16 GAX22618.1 - 1.3e-19 70.3 62.7 1.5e-15 57.0 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX22618.1 - 4e-05 22.7 37.8 0.033 13.1 14.3 3.1 1 1 0 2 2 2 2 Sugar (and other) transporter 60KD_IMP PF02096.20 GAX22618.1 - 0.14 12.1 4.7 4.7 7.1 0.5 2.9 2 1 0 2 2 2 0 60Kd inner membrane protein TMEM70 PF06979.12 GAX22618.1 - 0.43 11.0 2.9 23 5.4 0.2 2.9 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex EamA PF00892.20 GAX22619.1 - 1.4e-19 70.6 23.9 1.5e-10 41.4 11.3 3.4 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 GAX22619.1 - 0.0041 16.5 0.9 0.0076 15.6 0.3 1.7 1 1 1 2 2 2 1 Triose-phosphate Transporter family PT PF04886.12 GAX22620.1 - 4.8e-49 163.6 528.4 7.7e-05 22.2 13.8 33.2 15 5 15 30 30 30 22 PT repeat UVR PF02151.19 GAX22621.1 - 1.2 9.0 35.3 0.15 11.9 1.2 5.5 6 0 0 6 6 6 0 UvrB/uvrC motif Memo PF01875.17 GAX22622.1 - 4.6e-73 245.7 0.0 5.3e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein PP2C PF00481.21 GAX22623.1 - 2.2e-35 122.5 0.0 7.3e-35 120.8 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C cNMP_binding PF00027.29 GAX22623.1 - 2.4e-31 107.7 0.0 4.5e-16 58.7 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain SpoIIE PF07228.12 GAX22623.1 - 1.7e-06 28.1 0.0 0.00048 20.1 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) CoA_binding_2 PF13380.6 GAX22624.1 - 1.7e-37 128.5 0.2 2e-37 128.2 0.2 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 GAX22624.1 - 5.3e-08 33.5 0.1 8.6e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 CoA binding domain DeoC PF01791.9 GAX22624.1 - 0.01 15.5 0.1 0.017 14.7 0.1 1.4 1 1 0 1 1 1 0 DeoC/LacD family aldolase LRR_8 PF13855.6 GAX22625.1 - 3e-22 78.1 32.8 1.9e-08 33.9 3.0 5.5 1 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAX22625.1 - 1.9e-15 56.7 37.7 0.0008 19.8 0.1 7.4 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX22625.1 - 0.0017 18.6 28.0 6.8 7.7 0.1 10.1 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 GAX22625.1 - 0.5 10.6 30.6 6.6 7.1 0.1 8.5 9 0 0 9 9 9 0 Leucine Rich repeat LRR_9 PF14580.6 GAX22625.1 - 2.4 7.6 7.1 0.9 9.0 0.3 3.0 1 1 3 4 4 4 0 Leucine-rich repeat RCC_reductase PF06405.11 GAX22626.1 - 0.0022 17.2 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) VDE PF07137.11 GAX22627.1 - 5.9e-78 261.7 0.1 7.2e-78 261.4 0.1 1.1 1 0 0 1 1 1 1 VDE lipocalin domain WD40 PF00400.32 GAX22628.1 - 2.9e-21 75.4 9.8 0.00012 22.8 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX22628.1 - 1.1e-13 51.2 3.5 0.023 15.0 0.1 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX22628.1 - 0.00019 21.4 0.0 0.029 14.2 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAX22628.1 - 0.0014 17.6 0.1 0.0055 15.7 0.0 2.0 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 GAX22628.1 - 0.017 14.4 0.1 0.83 8.9 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PALB2_WD40 PF16756.5 GAX22628.1 - 0.03 13.3 3.5 0.16 10.8 0.2 2.5 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Pkinase PF00069.25 GAX22629.1 - 6.6e-59 199.4 0.0 1.1e-58 198.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22629.1 - 9.1e-28 97.2 0.0 1.5e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 GAX22629.1 - 3.3e-07 30.6 0.1 0.023 15.0 0.0 2.8 2 1 0 2 2 2 2 Regulator of G protein signaling domain Kinase-like PF14531.6 GAX22629.1 - 0.00018 21.0 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Aminotran_1_2 PF00155.21 GAX22630.1 - 1.1e-33 117.0 0.0 1.2e-33 116.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX22630.1 - 0.00023 19.8 0.0 0.00037 19.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAX22630.1 - 0.0023 17.0 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAX22630.1 - 0.0026 17.1 0.1 0.025 13.9 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAX22630.1 - 0.036 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Glyoxalase PF00903.25 GAX22631.1 - 4.6e-39 133.5 2.6 1.4e-21 77.0 0.2 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAX22631.1 - 1.5e-13 50.9 0.1 3.2e-05 24.2 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAX22631.1 - 0.00043 21.0 0.0 0.022 15.6 0.0 2.8 2 2 0 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.6 GAX22631.1 - 0.031 14.4 0.0 4.9 7.3 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal Glyoxalase_3 PF13468.6 GAX22631.1 - 0.11 12.6 0.0 1.6 8.8 0.0 2.7 2 1 0 2 2 2 0 Glyoxalase-like domain Med14 PF08638.11 GAX22632.1 - 0.0055 16.1 0.3 0.012 15.0 0.3 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 Aldo_ket_red PF00248.21 GAX22633.1 - 4.9e-25 88.3 0.0 7.3e-24 84.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Kin17_mid PF10357.9 GAX22634.1 - 2.8e-38 130.7 9.0 2.8e-38 130.7 9.0 2.5 2 1 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 GAX22634.1 - 4.9e-10 39.4 0.3 1.2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 GAX22634.1 - 4.8e-06 26.3 2.8 7.4e-06 25.7 0.5 2.3 2 0 0 2 2 2 1 KOW motif zf-C2H2_jaz PF12171.8 GAX22634.1 - 0.0034 17.6 2.4 0.0069 16.7 2.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding CAML PF14963.6 GAX22634.1 - 0.026 14.7 5.2 0.051 13.7 5.2 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand zf-met PF12874.7 GAX22634.1 - 0.027 14.9 4.2 0.056 13.8 4.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF2470 PF10615.9 GAX22634.1 - 0.035 14.8 0.0 0.12 13.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) zf-C2H2_2 PF12756.7 GAX22634.1 - 0.049 14.0 2.8 0.17 12.2 0.6 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pap_E4 PF02711.14 GAX22634.1 - 3.1 8.8 8.3 0.26 12.3 0.9 2.5 2 1 0 2 2 2 0 E4 protein Sacchrp_dh_NADP PF03435.18 GAX22635.1 - 1.7e-10 41.3 0.2 2.8e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 GAX22636.1 - 1.7e-26 93.0 34.9 1.7e-26 93.0 34.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily SMC_N PF02463.19 GAX22638.1 - 6.8e-09 35.5 0.9 0.0039 16.7 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAX22638.1 - 1.3e-06 29.1 0.6 4.3e-06 27.4 0.6 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAX22638.1 - 0.003 17.3 0.1 0.007 16.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX22638.1 - 0.0042 17.3 0.5 0.066 13.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAX22638.1 - 0.0065 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein IIGP PF05049.13 GAX22638.1 - 0.1 11.6 3.2 2.4 7.1 0.4 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 GAX22638.1 - 0.22 11.6 1.4 0.56 10.3 0.2 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 GAX22638.1 - 1.5 9.4 3.4 2.8 8.5 0.2 2.9 3 1 0 3 3 3 0 ABC transporter SPC22 PF04573.12 GAX22639.1 - 9.2e-47 158.7 0.0 1e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Pkinase_Tyr PF07714.17 GAX22640.1 - 7.6e-55 186.0 0.0 1.1e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX22640.1 - 2.9e-44 151.4 0.0 4.6e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAX22640.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX22640.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.7 GAX22641.1 - 1.8e-12 47.2 11.3 1.8e-05 25.0 0.2 5.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX22641.1 - 3.8e-10 39.4 9.9 5.1e-05 23.0 5.3 3.8 2 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 GAX22641.1 - 2.1e-07 30.6 0.5 1.4e-06 27.9 0.1 2.3 2 1 1 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 GAX22641.1 - 0.0065 16.4 2.2 39 4.7 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich repeat Ank_4 PF13637.6 GAX22642.1 - 1.6e-22 79.5 5.3 1e-07 32.4 0.0 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX22642.1 - 1.1e-20 74.0 0.2 1.9e-10 41.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX22642.1 - 3.9e-18 63.7 0.0 1.2e-05 25.2 0.1 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAX22642.1 - 1.4e-15 57.2 1.2 0.00026 21.2 0.3 5.3 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX22642.1 - 2.8e-13 49.6 0.0 0.00022 21.5 0.4 5.2 5 0 0 5 5 5 3 Ankyrin repeat DnaJ PF00226.31 GAX22642.1 - 1.9e-06 27.9 0.4 3.6e-06 27.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 GAX22643.1 - 1.1e-92 311.3 28.6 1.2e-71 241.9 15.0 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAX22643.1 - 4.5e-29 101.5 33.0 2.3e-28 99.2 18.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAX22643.1 - 0.0016 17.0 2.9 0.0016 17.0 2.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NADH-u_ox-rdase PF10785.9 GAX22643.1 - 2.4 8.9 6.5 34 5.2 0.0 4.0 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NAD_binding_10 PF13460.6 GAX22644.1 - 1.1e-06 28.7 0.0 0.0032 17.4 0.0 3.0 2 1 0 2 2 2 2 NAD(P)H-binding DapB_N PF01113.20 GAX22644.1 - 0.0016 18.5 0.1 0.0031 17.6 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 GAX22644.1 - 0.0019 17.7 0.0 0.0067 15.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAX22644.1 - 0.02 14.1 0.1 0.064 12.4 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Acyl-CoA_dh_1 PF00441.24 GAX22645.1 - 2.3e-30 105.8 0.1 3.9e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAX22645.1 - 3e-26 91.5 0.0 5.3e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAX22645.1 - 2.4e-21 76.5 0.0 5.4e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAX22645.1 - 4.1e-14 53.0 0.0 1.2e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HSF_DNA-bind PF00447.17 GAX22646.1 - 4.6e-09 36.8 0.5 8.8e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding EF-hand_7 PF13499.6 GAX22647.1 - 1.1e-05 25.8 3.4 0.74 10.3 0.0 4.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX22647.1 - 2.9e-05 23.6 4.1 2.4 8.3 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 GAX22647.1 - 0.015 14.8 6.1 53 3.7 0.2 5.0 5 0 0 5 5 5 0 EF hand EF-hand_8 PF13833.6 GAX22647.1 - 0.027 14.3 3.1 2.2 8.2 0.0 3.6 5 0 0 5 5 5 0 EF-hand domain pair DUF3695 PF12494.8 GAX22648.1 - 0.045 13.6 0.5 0.1 12.5 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3695) Pox_Ag35 PF03286.14 GAX22648.1 - 0.076 12.8 2.2 0.11 12.3 2.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RRM_1 PF00076.22 GAX22649.1 - 1.9e-16 59.6 0.0 2.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_LMP2 PF07415.11 GAX22649.1 - 5.4 5.7 3.8 7.7 5.2 3.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Ufd2P_core PF10408.9 GAX22651.1 - 6.3e-117 391.8 0.0 9.8e-117 391.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 GAX22651.1 - 4.8e-23 81.1 0.2 1.2e-22 79.8 0.2 1.7 1 0 0 1 1 1 1 U-box domain DUF2605 PF10792.9 GAX22651.1 - 0.39 10.7 2.0 0.79 9.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) PPR_2 PF13041.6 GAX22652.1 - 1.2e-16 60.6 2.9 3e-06 27.3 0.0 6.4 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.6 GAX22652.1 - 6.1e-09 35.8 6.0 0.012 15.6 0.5 5.9 5 2 1 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX22652.1 - 0.0023 17.4 1.8 0.29 10.4 0.3 3.0 2 2 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX22652.1 - 0.0079 16.4 10.5 0.16 12.2 0.0 5.5 5 1 0 5 5 5 1 PPR repeat MNE1 PF13762.6 GAX22652.1 - 0.023 14.7 0.5 0.1 12.6 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component PPR_1 PF12854.7 GAX22652.1 - 0.057 13.1 8.6 2.3 8.0 0.1 4.4 4 0 0 4 4 4 0 PPR repeat Rif1_N PF12231.8 GAX22652.1 - 0.061 12.3 1.9 0.25 10.3 0.3 2.6 3 0 0 3 3 3 0 Rap1-interacting factor 1 N terminal TPR_18 PF13512.6 GAX22652.1 - 0.12 12.5 0.1 6.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 GAX22653.1 - 9.6e-27 93.2 0.0 2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 GAX22653.1 - 5.8e-10 39.1 0.0 1.9e-07 31.0 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAX22653.1 - 3.7e-08 33.8 0.0 6.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 GAX22653.1 - 1.1e-05 25.3 0.0 4.4e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 GAX22653.1 - 3.6e-05 23.7 0.0 6.2e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX22653.1 - 5e-05 23.0 0.0 7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 GAX22653.1 - 0.00013 22.0 0.0 0.00029 21.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX22653.1 - 0.012 15.4 0.0 0.052 13.3 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin DUF953 PF06110.11 GAX22653.1 - 0.021 14.4 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 GAX22653.1 - 0.13 12.5 0.0 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 Glutaredoxin Thioredoxin_5 PF13743.6 GAX22653.1 - 0.13 11.9 0.0 2.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DUF929 PF06053.11 GAX22653.1 - 0.19 11.0 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) UPF0126 PF03458.13 GAX22655.1 - 0.22 11.4 7.9 2.5 8.0 0.1 3.1 2 1 1 3 3 3 0 UPF0126 domain Adaptin_N PF01602.20 GAX22656.1 - 1.9e-104 350.1 2.5 2.8e-104 349.6 2.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GAX22656.1 - 8.1e-46 155.9 0.2 4.5e-45 153.5 0.1 2.3 3 0 0 3 3 3 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 GAX22656.1 - 1.4e-34 118.6 0.0 5e-34 116.9 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GAX22656.1 - 4e-14 52.8 6.9 2.1e-06 28.0 0.4 5.1 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 GAX22656.1 - 1.2e-10 41.7 2.3 0.016 15.3 0.1 3.6 3 0 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX22656.1 - 0.00011 22.1 12.6 1 9.8 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 GAX22656.1 - 0.00014 22.3 10.3 0.03 14.8 2.8 3.8 2 1 1 3 3 3 2 HEAT-like repeat HEAT_PBS PF03130.16 GAX22656.1 - 0.068 13.9 2.9 25 5.9 0.3 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 GAX22656.1 - 0.38 10.5 4.9 26 4.5 0.3 4.1 4 2 1 5 5 5 0 rRNA processing/ribosome biogenesis PPR_2 PF13041.6 GAX22657.1 - 1.3e-09 38.1 1.9 0.31 11.3 0.0 5.7 5 1 0 5 5 5 3 PPR repeat family PPR_1 PF12854.7 GAX22657.1 - 1e-05 25.1 0.1 0.3 10.8 0.0 5.2 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 GAX22657.1 - 0.00076 19.5 0.3 2.3 8.4 0.0 4.6 3 1 2 5 5 5 1 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX22657.1 - 0.00078 18.9 1.3 0.46 9.8 0.1 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX22657.1 - 0.0071 16.5 6.9 0.066 13.5 0.0 5.0 6 0 0 6 6 6 1 PPR repeat UAA PF08449.11 GAX22658.1 - 3.6e-36 124.9 7.5 4.1e-36 124.7 7.5 1.0 1 0 0 1 1 1 1 UAA transporter family Ceramidase PF05875.12 GAX22658.1 - 0.0011 18.4 0.3 0.0017 17.8 0.3 1.3 1 0 0 1 1 1 1 Ceramidase EamA PF00892.20 GAX22658.1 - 0.003 17.7 7.1 0.003 17.7 7.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family WD40 PF00400.32 GAX22659.1 - 2e-40 136.0 19.3 2.3e-09 37.7 0.2 10.5 11 0 0 11 11 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX22659.1 - 3.1e-28 97.9 0.0 0.00028 21.1 0.0 7.8 5 3 2 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX22659.1 - 1.2e-07 31.0 0.0 0.069 12.1 0.0 4.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAX22659.1 - 5.2e-05 22.7 0.0 0.1 11.9 0.0 3.7 3 1 1 4 4 4 1 WD40-like domain DUF1513 PF07433.11 GAX22659.1 - 0.0044 16.2 1.6 1.5 7.8 0.0 3.3 3 1 1 4 4 4 2 Protein of unknown function (DUF1513) Lactonase PF10282.9 GAX22659.1 - 0.0054 16.0 0.0 26 4.0 0.0 4.0 4 1 0 4 4 4 0 Lactonase, 7-bladed beta-propeller ELYS-bb PF16687.5 GAX22659.1 - 0.013 14.2 0.0 1.2 7.7 0.0 3.0 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin Nucleoporin_N PF08801.11 GAX22659.1 - 0.026 13.3 0.2 20 3.8 0.0 4.1 4 2 1 6 6 6 0 Nup133 N terminal like CNH PF00780.22 GAX22659.1 - 0.036 13.7 0.0 4.5 6.8 0.0 3.0 2 1 0 2 2 2 0 CNH domain Frtz PF11768.8 GAX22659.1 - 0.041 12.2 0.0 12 4.1 0.0 3.2 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz CSTF_C PF14304.6 GAX22659.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal PALB2_WD40 PF16756.5 GAX22659.1 - 0.13 11.1 1.2 3.3 6.5 0.0 3.4 4 1 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Kelch_4 PF13418.6 GAX22659.1 - 0.2 11.7 0.6 32 4.6 0.2 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain WDCP PF15390.6 GAX22659.1 - 0.21 9.9 0.0 0.33 9.3 0.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family GlutR_N PF05201.15 GAX22661.1 - 3.3e-05 23.7 0.1 0.0023 17.7 0.1 2.2 2 0 0 2 2 2 2 Glutamyl-tRNAGlu reductase, N-terminal domain Methyltransf_31 PF13847.6 GAX22662.1 - 6.6e-10 39.0 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22662.1 - 4e-09 37.1 0.0 6.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX22662.1 - 5.6e-08 32.5 0.1 1.8e-07 30.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX22662.1 - 8e-08 32.9 0.0 1.6e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22662.1 - 2.1e-06 28.3 0.0 4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAX22662.1 - 1.9e-05 24.2 0.1 3.3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 GAX22662.1 - 0.00011 22.0 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAX22662.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX22662.1 - 0.042 13.2 0.0 0.086 12.2 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 GAX22662.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Met_10 PF02475.16 GAX22662.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_2 PF00891.18 GAX22662.1 - 0.15 11.4 0.0 0.33 10.2 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 GAX22662.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Hemerythrin PF01814.23 GAX22665.1 - 2.2e-07 31.5 0.5 2.7e-07 31.3 0.5 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Endonuc-dimeris PF09124.10 GAX22665.1 - 0.27 11.4 1.4 1.5 9.0 0.2 2.3 2 1 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation pXO2-34 PF17362.2 GAX22666.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function F-box-like PF12937.7 GAX22667.1 - 0.0082 16.0 0.4 0.049 13.5 0.4 2.3 1 1 0 1 1 1 1 F-box-like DUF3077 PF11275.8 GAX22667.1 - 0.029 14.6 0.1 0.071 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) F-box PF00646.33 GAX22667.1 - 0.056 13.3 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 F-box domain Peptidase_M20 PF01546.28 GAX22668.1 - 1.5e-36 126.1 0.0 2.5e-36 125.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAX22668.1 - 8.4e-15 54.6 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Kelch_4 PF13418.6 GAX22668.1 - 0.093 12.8 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain DnaJ PF00226.31 GAX22669.1 - 2e-16 59.9 0.0 8e-15 54.7 0.0 3.3 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 GAX22669.1 - 2.9e-10 39.5 9.9 0.0022 17.7 0.0 5.8 6 1 1 7 7 5 3 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 GAX22669.1 - 3.9e-10 39.4 9.6 3.9e-10 39.4 9.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX22669.1 - 3.4e-09 36.9 10.6 7e-09 35.9 10.6 1.6 1 0 0 1 1 1 1 Ring finger domain TPR_16 PF13432.6 GAX22669.1 - 3.7e-08 33.9 8.8 0.00051 20.6 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX22669.1 - 5.8e-08 32.3 15.9 0.0034 17.4 0.0 7.5 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX22669.1 - 9.6e-08 31.7 10.3 0.0045 17.1 0.1 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX22669.1 - 1.7e-07 31.4 19.1 0.015 15.6 0.2 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX22669.1 - 2.1e-07 31.2 17.1 1.6 9.8 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX22669.1 - 2.5e-07 30.6 3.1 0.48 10.9 0.0 5.9 7 0 0 7 7 4 1 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 GAX22669.1 - 2.9e-07 30.2 7.1 5.9e-07 29.2 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.6 GAX22669.1 - 3.4e-07 30.7 17.4 0.0018 18.8 0.2 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat zf-C3HC4 PF00097.25 GAX22669.1 - 9.5e-07 28.6 9.3 2.2e-06 27.4 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX22669.1 - 3.8e-06 26.7 8.4 7.8e-06 25.8 8.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAX22669.1 - 1.9e-05 24.8 8.7 5.9e-05 23.3 8.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX22669.1 - 0.00014 21.8 10.0 0.00039 20.4 10.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DUF3856 PF12968.7 GAX22669.1 - 0.00028 20.9 7.1 0.34 11.0 0.3 3.8 2 1 0 2 2 2 2 Domain of Unknown Function (DUF3856) Prok-RING_4 PF14447.6 GAX22669.1 - 0.00031 20.6 8.4 0.00031 20.6 8.4 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 Sina PF03145.16 GAX22669.1 - 0.00048 20.1 0.8 0.00088 19.3 0.2 1.7 1 1 0 1 1 1 1 Seven in absentia protein family ANAPC3 PF12895.7 GAX22669.1 - 0.0012 19.0 16.8 0.072 13.3 0.3 4.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAX22669.1 - 0.0059 17.2 15.9 0.012 16.2 0.2 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX22669.1 - 0.0088 15.7 3.7 9.9 5.9 0.0 4.9 4 1 1 5 5 5 0 TPR repeat RIP PF00161.19 GAX22669.1 - 0.013 15.1 0.1 0.033 13.8 0.1 1.7 1 0 0 1 1 1 0 Ribosome inactivating protein zf-ANAPC11 PF12861.7 GAX22669.1 - 0.018 15.1 5.0 0.035 14.2 5.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX22669.1 - 0.023 14.3 7.1 0.036 13.7 6.4 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 GAX22669.1 - 0.026 14.7 7.9 0.061 13.5 7.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 GAX22669.1 - 0.038 13.7 5.3 0.21 11.4 5.7 2.1 1 1 1 2 2 2 0 RING-like zinc finger TPR_7 PF13176.6 GAX22669.1 - 0.068 13.2 6.8 0.44 10.7 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TALPID3 PF15324.6 GAX22669.1 - 0.17 9.5 1.3 0.25 9.0 1.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target zf-RING_4 PF14570.6 GAX22669.1 - 0.21 11.4 6.4 0.43 10.4 6.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 GAX22669.1 - 0.71 9.6 5.7 1.7 8.4 5.7 1.7 1 0 0 1 1 1 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 GAX22669.1 - 0.86 9.6 8.3 2.1 8.4 8.3 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-C3HC4_4 PF15227.6 GAX22669.1 - 2.6 8.3 9.1 6.6 7.0 9.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 GAX22670.1 - 9.6e-63 212.0 0.0 2e-62 210.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22670.1 - 6.9e-34 117.3 0.0 1.6e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX22670.1 - 1.7e-08 34.1 0.0 4e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAX22670.1 - 0.00018 21.5 1.3 0.00093 19.2 1.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAX22670.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 EF-hand_like PF09279.11 GAX22670.1 - 0.53 10.8 2.7 1.6 9.3 2.7 1.9 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF87 PF01935.17 GAX22670.1 - 0.72 9.9 3.4 1.7 8.7 3.4 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain DEAD PF00270.29 GAX22671.1 - 2.5e-42 144.6 0.1 5.1e-42 143.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX22671.1 - 5e-30 104.1 0.0 2.4e-29 101.9 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX22671.1 - 1.3e-06 28.5 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAX22671.1 - 5.4e-06 25.9 1.4 7.4e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 GAX22671.1 - 0.0075 16.6 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX22671.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAX22671.1 - 0.014 15.8 0.1 0.027 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 GAX22671.1 - 0.067 12.6 0.1 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Headcase PF16002.5 GAX22671.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Headcase protein UTP25 PF06862.12 GAX22671.1 - 0.078 11.7 0.0 0.27 9.9 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DENN PF02141.21 GAX22673.1 - 6.9e-23 81.6 0.5 1.6e-22 80.4 0.5 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain PDZ PF00595.24 GAX22673.1 - 1.2e-06 28.7 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Glyco_trans_2_3 PF13632.6 GAX22674.1 - 9.6e-17 61.5 1.7 9.6e-17 61.5 1.7 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 SIR2 PF02146.17 GAX22675.1 - 1.2e-13 51.3 0.4 8.4e-11 42.1 0.4 2.7 1 1 0 1 1 1 1 Sir2 family MscS_porin PF12795.7 GAX22675.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Motile_Sperm PF00635.26 GAX22677.1 - 5.5e-15 55.2 0.0 2.3e-14 53.2 0.0 2.0 2 1 0 2 2 2 1 MSP (Major sperm protein) domain DUF4407 PF14362.6 GAX22677.1 - 0.034 13.5 0.2 0.042 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 GAX22677.1 - 0.079 11.8 2.4 0.1 11.5 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DNA_ligase_A_M PF01068.21 GAX22678.1 - 0.04 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain mRNA_cap_enzyme PF01331.19 GAX22678.1 - 0.094 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Methyltransf_31 PF13847.6 GAX22681.1 - 2.6e-29 102.0 0.0 3.9e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX22681.1 - 5.6e-18 65.4 0.1 1.1e-17 64.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX22681.1 - 3.3e-16 59.7 0.1 7.5e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22681.1 - 1.4e-13 51.0 0.0 2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22681.1 - 1.1e-12 48.6 0.1 2.3e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX22681.1 - 1.4e-11 44.2 0.0 2.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 GAX22681.1 - 3.2e-06 26.8 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX22681.1 - 3.6e-05 23.4 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAX22681.1 - 0.00056 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.26 GAX22681.1 - 0.0021 18.0 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMAS PF02353.20 GAX22681.1 - 0.0098 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 GAX22681.1 - 0.013 15.6 0.0 0.049 13.7 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 GAX22681.1 - 0.034 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 GAX22681.1 - 0.035 13.0 0.0 0.12 11.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) DOT1 PF08123.13 GAX22681.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.14 GAX22681.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 GAX22681.1 - 0.19 11.5 0.5 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase ADK_lid PF05191.14 GAX22681.1 - 0.3 11.1 2.2 0.83 9.7 2.2 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid Fer2 PF00111.27 GAX22682.1 - 2.8e-08 33.6 0.4 2.3e-06 27.4 0.2 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 GAX22682.1 - 0.04 14.0 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ank_5 PF13857.6 GAX22683.1 - 3.3e-06 27.3 0.1 2.2e-05 24.6 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX22683.1 - 4.1e-06 27.3 0.0 1.1e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX22683.1 - 0.0003 21.3 0.0 0.013 16.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) OTU PF02338.19 GAX22684.1 - 3.5e-20 72.8 0.9 5.7e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAX22684.1 - 0.00028 20.4 0.0 0.41 10.1 0.0 2.5 1 1 1 2 2 2 2 Peptidase C65 Otubain DUF4820 PF16091.5 GAX22684.1 - 0.16 11.3 6.0 0.23 10.8 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) GvpL_GvpF PF06386.11 GAX22684.1 - 2.4 8.0 8.3 3.7 7.4 8.3 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ank_5 PF13857.6 GAX22685.1 - 1.1e-05 25.6 0.0 8.7e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX22685.1 - 0.097 13.3 0.1 4.3 8.0 0.2 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX22685.1 - 0.15 12.7 0.4 6.2 7.7 0.1 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 GAX22688.1 - 9.9e-06 25.7 0.0 0.00054 20.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX22688.1 - 0.00059 20.1 0.2 3.3 8.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 GAX22688.1 - 0.0014 19.2 0.0 0.0036 17.8 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Maf1 PF09174.10 GAX22689.1 - 1.2e-32 113.5 0.0 9e-25 87.8 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator Gal-bind_lectin PF00337.22 GAX22690.1 - 7e-07 28.9 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin RRM_1 PF00076.22 GAX22690.1 - 0.00014 21.6 0.0 0.00057 19.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Utp14 PF04615.13 GAX22690.1 - 0.13 10.9 23.6 0.19 10.2 23.6 1.2 1 0 0 1 1 1 0 Utp14 protein NOA36 PF06524.12 GAX22690.1 - 1 8.6 10.6 1.7 7.9 10.6 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3295 PF11702.8 GAX22690.1 - 1.1 8.6 14.1 0.83 8.9 12.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3295) Myc_N PF01056.18 GAX22690.1 - 1.9 8.3 11.2 3 7.6 11.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Kinesin PF00225.23 GAX22691.1 - 1.8e-78 263.8 0.1 1.8e-78 263.8 0.1 2.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAX22691.1 - 1.7e-15 57.3 0.7 6.4e-15 55.4 0.0 2.4 3 0 0 3 3 2 1 Microtubule binding bZIP_1 PF00170.21 GAX22691.1 - 0.00056 20.0 2.9 0.00056 20.0 2.9 4.9 5 0 0 5 5 4 1 bZIP transcription factor ZapB PF06005.12 GAX22691.1 - 0.0022 18.4 5.1 0.0022 18.4 5.1 3.7 1 1 1 2 2 1 1 Cell division protein ZapB Filament PF00038.21 GAX22691.1 - 0.0026 17.4 25.2 0.0065 16.1 25.2 1.6 1 0 0 1 1 1 1 Intermediate filament protein ADIP PF11559.8 GAX22691.1 - 0.004 17.3 12.7 0.004 17.3 12.7 3.3 3 1 1 4 4 3 1 Afadin- and alpha -actinin-Binding DivIC PF04977.15 GAX22691.1 - 0.0097 15.7 3.1 0.0097 15.7 3.1 3.7 2 1 1 3 3 3 1 Septum formation initiator CENP-H PF05837.12 GAX22691.1 - 0.011 16.2 23.3 0.11 12.9 7.0 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Fez1 PF06818.15 GAX22691.1 - 0.019 15.5 32.1 0.097 13.1 9.3 3.4 2 1 1 3 3 3 0 Fez1 TPR_MLP1_2 PF07926.12 GAX22691.1 - 0.029 14.4 25.3 0.16 12.1 9.1 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 GAX22691.1 - 0.12 10.5 25.1 0.23 9.6 25.1 1.4 1 0 0 1 1 1 0 HOOK protein HALZ PF02183.18 GAX22691.1 - 0.21 11.9 5.6 0.25 11.6 0.6 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper dCache_1 PF02743.18 GAX22691.1 - 0.5 10.1 3.1 1.5 8.5 1.4 2.6 3 0 0 3 3 3 0 Cache domain DUF4709 PF15821.5 GAX22691.1 - 0.67 10.3 17.7 0.18 12.1 6.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) Csm1_N PF18504.1 GAX22691.1 - 1.2 9.5 30.2 0.41 11.0 6.1 4.8 2 1 2 4 4 4 0 Csm1 N-terminal domain Apolipoprotein PF01442.18 GAX22691.1 - 1.6 8.6 27.3 20 5.0 26.1 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3584 PF12128.8 GAX22691.1 - 2 5.8 26.0 5.8 4.3 26.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_Mu_Gam PF07352.12 GAX22691.1 - 2.4 8.1 20.5 0.73 9.7 10.0 2.7 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF4201 PF13870.6 GAX22691.1 - 2.6 7.7 24.5 0.17 11.6 3.4 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) ApoO PF09769.9 GAX22691.1 - 2.7 8.0 7.5 2.9 7.9 0.3 2.6 1 1 1 2 2 2 0 Apolipoprotein O WXG100 PF06013.12 GAX22691.1 - 4.3 7.6 14.0 0.07 13.4 3.5 3.1 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF489 PF04356.12 GAX22691.1 - 4.4 7.3 13.5 3.5 7.6 3.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF4407 PF14362.6 GAX22691.1 - 5 6.4 18.5 16 4.7 18.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 GAX22691.1 - 5.1 7.5 25.2 2.9 8.2 10.2 3.2 1 1 2 3 3 2 0 Plant protein of unknown function (DUF641) Seryl_tRNA_N PF02403.22 GAX22691.1 - 5.5 7.3 26.4 0.81 9.9 9.1 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 GAX22691.1 - 8.7 6.5 17.4 5.4 7.2 11.4 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-RING_2 PF13639.6 GAX22692.1 - 1.9e-10 40.9 4.2 4.3e-10 39.8 4.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX22692.1 - 1e-06 28.9 4.7 2.9e-06 27.5 4.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX22692.1 - 1.8e-06 27.7 3.6 4.5e-06 26.4 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX22692.1 - 3.2e-06 26.8 1.1 7.9e-06 25.5 1.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAX22692.1 - 6.1e-05 23.0 1.2 0.00017 21.6 1.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX22692.1 - 0.00024 20.9 2.8 0.00063 19.6 2.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX22692.1 - 0.0005 20.2 3.5 0.0013 18.8 3.5 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 GAX22692.1 - 0.0011 19.0 3.0 0.0028 17.6 3.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GAX22692.1 - 0.0042 16.9 1.9 0.0042 16.9 1.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX22692.1 - 0.009 16.0 1.6 0.009 16.0 1.6 1.9 2 0 0 2 2 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAX22692.1 - 0.018 14.7 5.0 0.048 13.3 5.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 GAX22692.1 - 0.059 13.4 5.7 0.19 11.8 5.7 2.0 1 0 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 GAX22692.1 - 0.61 10.1 4.5 3.1 7.8 1.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 GAX22692.1 - 1.2 9.4 7.1 0.85 10.0 3.7 2.4 2 0 0 2 2 2 0 RING-like domain Aldo_ket_red PF00248.21 GAX22693.1 - 2.9e-73 246.6 0.0 3.4e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PH PF00169.29 GAX22694.1 - 6.1e-18 65.3 0.0 6.6e-07 29.8 0.0 4.0 3 1 1 4 4 4 2 PH domain PH_9 PF15410.6 GAX22694.1 - 0.073 13.4 3.8 5.5 7.4 0.0 4.1 3 1 0 3 3 3 0 Pleckstrin homology domain CRAL_TRIO_N PF03765.15 GAX22694.1 - 0.09 13.0 0.1 0.69 10.1 0.1 2.4 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain AAA_28 PF13521.6 GAX22696.1 - 3.8e-27 95.5 0.0 6.1e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Pestivirus_E2 PF16329.5 GAX22696.1 - 0.021 13.7 0.0 0.044 12.6 0.0 1.4 2 0 0 2 2 2 0 Pestivirus envelope glycoprotein E2 NTPase_1 PF03266.15 GAX22696.1 - 0.036 14.0 0.0 0.43 10.5 0.0 2.3 1 1 1 2 2 2 0 NTPase AAA_33 PF13671.6 GAX22696.1 - 0.13 12.4 0.1 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3275 PF11679.8 GAX22698.1 - 0.14 12.1 2.1 0.15 12.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Hc1 PF07432.13 GAX22698.1 - 0.28 11.6 20.1 0.43 10.9 20.1 1.3 1 0 0 1 1 1 0 Histone H1-like protein Hc1 DUF4813 PF16072.5 GAX22698.1 - 1.3 8.6 12.1 2.1 8.0 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Aldo_ket_red PF00248.21 GAX22699.1 - 7.6e-16 58.1 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family PolyA_pol PF01743.20 GAX22700.1 - 2.5e-26 92.6 0.1 6e-24 84.9 0.1 2.5 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAX22700.1 - 7.3e-05 22.5 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A TRAM_LAG1_CLN8 PF03798.16 GAX22701.1 - 4.3e-06 26.6 20.5 5.2e-06 26.3 20.5 1.1 1 0 0 1 1 1 1 TLC domain Tubulin PF00091.25 GAX22702.1 - 4.5e-68 229.3 0.0 9.5e-68 228.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAX22702.1 - 7.5e-43 145.7 0.0 1.6e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAX22702.1 - 8.2e-05 22.9 0.4 0.0017 18.7 0.4 2.4 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GAX22702.1 - 0.0086 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin like WD40 PF00400.32 GAX22704.1 - 6.1e-10 39.5 4.0 0.18 12.7 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.6 GAX22704.1 - 0.00016 22.0 2.8 0.4 11.2 0.1 4.6 3 1 1 4 4 4 1 PQQ-like domain ANAPC4_WD40 PF12894.7 GAX22704.1 - 0.0018 18.6 0.0 25 5.2 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX22704.1 - 0.0066 15.8 0.0 0.06 12.7 0.0 2.2 2 1 0 2 2 2 1 WD40-like domain FliD_C PF07195.12 GAX22704.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TRAM_LAG1_CLN8 PF03798.16 GAX22705.1 - 9.3e-11 41.8 23.1 1.2e-10 41.5 23.1 1.1 1 0 0 1 1 1 1 TLC domain DUF493 PF04359.14 GAX22706.1 - 5.9e-18 65.2 0.1 1.3e-17 64.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF493) MatE PF01554.18 GAX22707.1 - 3.2e-14 52.9 20.8 4.3e-12 46.0 5.0 3.6 3 1 1 4 4 4 2 MatE Polysacc_synt_C PF14667.6 GAX22707.1 - 4.6e-07 30.0 6.7 4.6e-07 30.0 6.7 3.0 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain SET PF00856.28 GAX22708.1 - 4.5e-05 23.9 0.0 0.00021 21.7 0.0 2.0 1 1 0 1 1 1 1 SET domain tRNA-synt_2b PF00587.25 GAX22709.1 - 1.1e-44 152.5 0.0 2.2e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAX22709.1 - 1.4e-16 60.4 0.2 6.3e-16 58.3 0.2 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 GAX22709.1 - 1.2e-12 47.7 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Cyclin PF08613.11 GAX22710.1 - 7.3e-35 120.7 2.1 1.7e-34 119.5 2.0 1.6 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAX22710.1 - 1e-11 44.6 0.1 1.7e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PEX11 PF05648.14 GAX22711.1 - 2.5e-20 72.9 8.3 2.9e-13 49.8 0.2 3.1 3 1 0 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) Cys_rich_CPXG PF14255.6 GAX22711.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG DUF3395 PF11875.8 GAX22712.1 - 1.4e-22 80.3 1.7 1.2e-21 77.3 1.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) Terminase_5 PF06056.12 GAX22712.1 - 0.064 13.2 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF2937 PF11157.8 GAX22712.1 - 0.14 11.8 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Efg1 PF10153.9 GAX22713.1 - 4.6e-13 49.5 10.1 4.6e-13 49.5 10.1 3.0 2 1 0 2 2 2 1 rRNA-processing protein Efg1 DUF5499 PF17603.2 GAX22713.1 - 0.025 15.2 0.4 0.078 13.6 0.4 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5499) Pkinase PF00069.25 GAX22714.1 - 3.9e-22 78.9 0.0 5.3e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22714.1 - 6.1e-08 32.3 0.0 9.7e-07 28.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX22714.1 - 8.2e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UPF0225 PF17775.1 GAX22715.1 - 1.2e-17 64.5 0.0 1.6e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 GAX22715.1 - 0.00031 20.6 8.2 0.00061 19.7 8.2 1.5 1 0 0 1 1 1 1 SEC-C motif LEA_3 PF03242.13 GAX22715.1 - 0.052 14.3 0.0 0.24 12.2 0.0 2.0 3 0 0 3 3 3 0 Late embryogenesis abundant protein FGGY_C PF02782.16 GAX22716.1 - 8.6e-61 205.1 4.9 1.6e-59 201.0 2.0 2.7 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAX22716.1 - 8.9e-60 202.3 0.1 1.4e-59 201.7 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DHR-2 PF06920.13 GAX22717.1 - 4.8e-18 65.1 0.0 6.4e-08 31.7 0.0 3.2 3 0 0 3 3 3 3 Dock homology region 2 DDHD PF02862.17 GAX22718.1 - 1.3e-20 74.6 0.0 1.3e-18 68.0 0.0 2.5 1 1 0 1 1 1 1 DDHD domain DUF676 PF05057.14 GAX22718.1 - 0.053 13.0 0.1 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) CIA30 PF08547.12 GAX22719.1 - 3.4e-14 53.2 0.0 5.4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 GAX22719.1 - 0.057 13.4 0.2 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Surface glycan-binding protein B xyloglucan binding domain DUF2009 PF09418.10 GAX22720.1 - 1.3e-191 637.6 0.0 1.8e-191 637.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) HATPase_c PF02518.26 GAX22720.1 - 0.0001 22.7 0.0 0.04 14.4 0.0 2.9 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX22720.1 - 0.00081 19.2 0.0 0.041 13.7 0.0 3.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BNIP2 PF12496.8 GAX22720.1 - 0.92 9.9 5.9 0.34 11.4 1.8 2.1 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4637 PF15470.6 GAX22720.1 - 6.5 6.5 9.1 0.34 10.6 3.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Hydrolase_4 PF12146.8 GAX22721.1 - 6.7e-09 35.4 0.7 0.00023 20.5 0.1 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase PF00756.20 GAX22721.1 - 6.1e-05 22.8 0.1 0.00014 21.6 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.7 GAX22721.1 - 0.0001 23.0 1.6 0.00019 22.1 1.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 GAX22721.1 - 0.00036 19.5 0.0 0.00057 18.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 GAX22721.1 - 0.0064 16.2 0.1 0.045 13.4 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAX22721.1 - 0.054 13.3 0.1 30 4.3 0.1 3.1 3 1 0 3 3 3 0 Phospholipase/Carboxylesterase TYW3 PF02676.14 GAX22722.1 - 1.7e-51 174.6 0.0 2.6e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 Kelch_4 PF13418.6 GAX22722.1 - 5.4e-15 55.1 1.5 0.00033 20.6 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX22722.1 - 9.2e-07 28.9 1.5 2.1 8.8 0.0 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 GAX22722.1 - 5.4e-06 26.3 0.0 1 9.4 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 GAX22722.1 - 0.00014 22.0 2.4 0.039 14.3 0.0 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAX22724.1 - 8.7e-42 140.5 13.2 6.2e-09 35.3 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAX22724.1 - 6.7e-35 118.7 19.3 3.3e-11 43.2 0.8 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAX22724.1 - 3.7e-29 100.2 19.3 7.8e-05 22.6 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 GAX22724.1 - 1.1e-28 98.1 15.0 7.2e-07 28.9 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAX22724.1 - 1e-27 95.4 18.4 2.3e-05 24.5 0.1 6.4 4 2 2 6 6 6 5 Kelch motif BTB PF00651.31 GAX22724.1 - 2.5e-25 88.8 0.7 2.5e-25 88.8 0.7 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 GAX22724.1 - 9.5e-23 80.0 18.8 1.5e-06 28.1 0.3 6.4 5 1 1 6 6 6 4 Galactose oxidase, central domain BACK PF07707.15 GAX22724.1 - 2.7e-05 24.2 1.6 0.00014 22.0 0.2 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 GAX22724.1 - 0.058 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) SET PF00856.28 GAX22725.1 - 5.2e-12 46.5 0.1 7e-08 33.0 0.0 2.2 1 1 1 2 2 2 2 SET domain Viral_DNA_Zn_bi PF03728.13 GAX22725.1 - 0.015 15.8 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain NAD_binding_10 PF13460.6 GAX22727.1 - 6.6e-27 94.6 0.0 2.3e-26 92.8 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 GAX22727.1 - 0.0055 17.1 0.0 0.0091 16.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX22727.1 - 0.021 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 GAX22727.1 - 0.044 13.3 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 GAX22727.1 - 0.064 12.7 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX22727.1 - 0.19 10.7 0.0 0.78 8.7 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acetyltransf_1 PF00583.25 GAX22728.1 - 6.2e-11 42.6 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAX22728.1 - 1.1e-07 31.7 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 GAX22728.1 - 9.6e-07 29.2 0.0 1.7e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX22728.1 - 7e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX22728.1 - 0.028 14.5 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAX22728.1 - 0.046 13.9 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAX22728.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase DUF5465 PF17553.2 GAX22729.1 - 0.031 14.7 0.2 0.12 13.0 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5465) DNA_pol_E_B PF04042.16 GAX22729.1 - 0.048 13.0 0.0 0.67 9.3 0.0 2.3 1 1 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Ras PF00071.22 GAX22730.1 - 1.1e-46 158.4 0.0 1.3e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX22730.1 - 6e-27 94.3 0.1 1.2e-26 93.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX22730.1 - 2.5e-14 53.1 0.0 3.2e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAX22730.1 - 4.2e-07 30.0 0.0 0.0044 16.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAX22730.1 - 4.7e-06 26.2 0.0 5.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX22730.1 - 1.4e-05 25.1 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAX22730.1 - 8.4e-05 22.3 0.0 0.00019 21.2 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 GAX22730.1 - 0.0007 19.0 0.0 0.00091 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 GAX22730.1 - 0.0033 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX22730.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DLIC PF05783.11 GAX22730.1 - 0.016 14.1 0.1 0.27 10.0 0.1 2.2 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 GAX22730.1 - 0.02 15.3 0.1 0.047 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 GAX22730.1 - 0.032 14.5 0.0 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX22730.1 - 0.075 13.3 0.0 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX22730.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Pkinase PF00069.25 GAX22731.1 - 4.7e-32 111.4 0.0 1.8e-31 109.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22731.1 - 4.5e-31 108.1 0.0 6.5e-30 104.3 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 GAX22732.1 - 1.3e-16 60.9 0.0 9.2e-13 48.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX22732.1 - 1.4e-13 51.0 0.0 9.6e-07 29.2 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX22732.1 - 4.5e-13 49.0 0.0 0.0091 16.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 GAX22732.1 - 6.8e-11 42.2 0.0 3.1e-05 24.2 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX22732.1 - 2.8e-10 39.5 0.0 0.03 14.8 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat YfmQ PF10787.9 GAX22732.1 - 0.048 13.4 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Thioredoxin PF00085.20 GAX22733.1 - 1.1e-21 76.7 0.3 2.9e-21 75.4 0.0 1.8 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX22733.1 - 6.9e-05 23.3 0.1 0.00032 21.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX22733.1 - 0.0073 16.6 0.4 0.04 14.3 0.0 2.3 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GAX22733.1 - 0.012 15.8 0.0 0.072 13.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 GAX22733.1 - 0.039 13.9 0.6 0.12 12.3 0.1 2.1 2 1 0 2 2 2 0 AhpC/TSA family DUF932 PF06067.11 GAX22733.1 - 0.048 13.4 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) GDA1_CD39 PF01150.17 GAX22734.1 - 6.6e-58 196.3 0.0 3e-55 187.6 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Antibiotic_NAT PF02522.14 GAX22735.1 - 0.03 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase Cpn60_TCP1 PF00118.24 GAX22736.1 - 5.4e-149 497.0 7.7 6.4e-149 496.7 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 GAX22737.1 - 2.9e-44 151.4 0.0 8.1e-44 150.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22737.1 - 2.9e-21 75.9 0.0 6.1e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 GAX22737.1 - 4.3e-06 26.4 0.1 0.17 12.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 GAX22737.1 - 1.9e-05 23.7 0.0 1.9e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase TPR_12 PF13424.6 GAX22737.1 - 2.8e-05 24.3 2.8 0.00011 22.5 1.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat APH PF01636.23 GAX22737.1 - 7.5e-05 22.8 0.4 7.5e-05 22.8 0.4 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX22737.1 - 0.00073 18.9 0.4 0.0046 16.3 0.0 2.2 2 1 0 3 3 3 1 Kinase-like TPR_1 PF00515.28 GAX22737.1 - 0.0014 18.4 0.7 0.58 10.1 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Hydin_ADK PF17213.3 GAX22737.1 - 0.0024 18.2 3.6 0.005 17.1 3.6 1.6 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain RIO1 PF01163.22 GAX22737.1 - 0.0044 16.7 7.2 0.0097 15.5 0.3 2.4 1 1 0 2 2 2 1 RIO1 family Kdo PF06293.14 GAX22737.1 - 0.0049 16.2 2.0 0.0049 16.2 2.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HupH_C PF04809.13 GAX22737.1 - 0.014 15.1 0.1 0.063 13.0 0.0 2.0 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region FTA2 PF13095.6 GAX22737.1 - 0.03 14.0 0.5 0.66 9.6 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TPR_16 PF13432.6 GAX22737.1 - 0.054 14.2 0.4 5 7.8 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX22737.1 - 0.055 13.5 1.4 1.6 8.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 GAX22737.1 - 0.075 13.1 1.2 0.83 9.8 0.1 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 GAX22737.1 - 0.11 13.0 6.6 5.3 7.6 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Choline_kinase PF01633.20 GAX22737.1 - 0.66 9.5 9.2 0.14 11.7 4.7 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF3701 PF12482.8 GAX22738.1 - 0.0018 18.3 0.1 0.0046 17.0 0.1 1.7 1 0 0 1 1 1 1 Phage integrase protein CMD PF02627.20 GAX22738.1 - 0.016 15.2 0.4 0.07 13.2 0.0 2.2 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family Ssu72 PF04722.13 GAX22739.1 - 1.5e-52 177.9 0.0 1.7e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GBR_NSP5 PF17580.2 GAX22739.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 SKN1 PF03935.15 GAX22741.1 - 7.2e-57 192.9 9.5 5.6e-50 170.2 5.3 4.3 3 1 0 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAX22741.1 - 9.4e-05 22.0 0.2 0.36 10.3 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 EGF_2 PF07974.13 GAX22741.1 - 0.0044 17.3 6.3 0.0044 17.3 6.3 2.3 2 1 0 2 2 2 1 EGF-like domain PT PF04886.12 GAX22741.1 - 6.1 6.5 14.5 0.16 11.6 7.6 2.1 2 0 0 2 2 2 0 PT repeat TLC PF03219.14 GAX22742.1 - 1.3e-05 24.2 17.2 0.0035 16.1 9.4 3.4 2 1 0 2 2 2 2 TLC ATP/ADP transporter DUF5104 PF17117.5 GAX22744.1 - 0.081 13.4 1.2 0.14 12.6 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5104) Syntaxin-6_N PF09177.11 GAX22744.1 - 0.21 12.2 1.9 0.29 11.7 1.9 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal NFACT-R_1 PF05670.13 GAX22745.1 - 1.2e-08 35.6 0.0 6.2e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 NFACT protein RNA binding domain DAO PF01266.24 GAX22746.1 - 2.5e-46 158.9 0.3 2.9e-46 158.7 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX22746.1 - 6.6e-06 25.6 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX22746.1 - 7.2e-05 22.1 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAX22746.1 - 0.00013 22.1 0.4 0.00026 21.1 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX22746.1 - 0.0077 15.3 0.0 0.89 8.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAX22746.1 - 0.028 13.6 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 GAX22746.1 - 0.043 12.9 0.0 0.47 9.5 0.0 2.1 1 1 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAX22746.1 - 0.054 12.3 0.9 6.7 5.4 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 GAX22746.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAX22746.1 - 0.1 13.2 0.1 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PPR_2 PF13041.6 GAX22747.1 - 2e-22 79.1 0.0 8.8e-05 22.6 0.1 8.3 8 1 0 8 8 8 4 PPR repeat family Smr PF01713.21 GAX22747.1 - 9.7e-08 32.3 0.0 2.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Smr domain PPR PF01535.20 GAX22747.1 - 4.6e-07 29.6 17.2 0.032 14.5 0.0 8.7 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 GAX22747.1 - 5.6e-07 29.5 4.0 0.16 12.1 0.0 5.6 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX22747.1 - 1.1e-05 25.0 8.9 0.092 12.5 0.2 6.4 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 GAX22747.1 - 0.0084 15.5 0.3 0.0084 15.5 0.3 3.9 5 1 0 5 5 5 1 Pentacotripeptide-repeat region of PRORP Sulf_transp PF04143.14 GAX22748.1 - 4.8e-15 55.9 21.9 1.6e-10 41.1 3.3 3.6 4 0 0 4 4 4 3 Sulphur transport Ribosomal_L3 PF00297.22 GAX22749.1 - 6.4e-16 58.3 4.4 6.5e-15 55.0 0.4 2.4 2 1 1 3 3 3 2 Ribosomal protein L3 Ribosomal_L39 PF00832.20 GAX22751.1 - 0.16 11.7 0.5 0.28 10.9 0.5 1.4 1 0 0 1 1 1 0 Ribosomal L39 protein RT_RNaseH_2 PF17919.1 GAX22752.1 - 2.1e-32 111.1 0.1 9.5e-32 109.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAX22752.1 - 6.4e-28 97.1 0.0 4.7e-27 94.3 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAX22752.1 - 4.6e-21 75.4 0.0 1.1e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GAX22752.1 - 3.2e-16 59.2 3.3 3.2e-16 59.2 3.3 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GAX22752.1 - 9.8e-11 41.9 0.0 5.3e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GAX22752.1 - 0.00068 20.2 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GAX22752.1 - 0.0072 16.5 0.3 0.069 13.4 0.2 2.7 3 0 0 3 3 3 1 H2C2 zinc finger CLP_protease PF00574.23 GAX22753.1 - 5.2e-79 264.4 0.0 6.2e-79 264.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease Chisel PF15355.6 GAX22753.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel W2 PF02020.18 GAX22754.1 - 4.5e-13 49.1 2.2 9.7e-13 48.1 2.2 1.5 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Glyoxalase_4 PF13669.6 GAX22756.1 - 9.4e-05 22.7 0.1 0.57 10.5 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Prok-TraM PF09228.10 GAX22756.1 - 0.076 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM zf-RING_2 PF13639.6 GAX22757.1 - 1e-10 41.8 14.4 2.2e-10 40.7 14.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX22757.1 - 3.8e-07 30.3 8.9 1e-06 28.9 8.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAX22757.1 - 1.3e-06 28.0 11.0 1.3e-06 28.0 11.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX22757.1 - 2.8e-06 27.1 12.8 5.3e-06 26.2 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX22757.1 - 5.7e-05 23.1 4.7 5.7e-05 23.1 4.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX22757.1 - 0.0001 22.1 12.6 0.00019 21.2 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX22757.1 - 0.00051 19.9 12.8 0.00089 19.2 12.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAX22757.1 - 0.00067 19.2 9.1 0.0015 18.1 9.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 GAX22757.1 - 0.00092 19.0 12.8 0.0017 18.1 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX22757.1 - 0.0063 16.5 5.0 0.017 15.2 5.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAX22757.1 - 0.019 14.8 11.2 0.039 13.8 11.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF998 PF06197.13 GAX22757.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF998) Prok-RING_1 PF14446.6 GAX22757.1 - 0.54 10.2 12.0 0.64 10.0 9.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 GAX22757.1 - 0.7 9.8 5.6 1.5 8.7 5.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 GAX22757.1 - 2 8.6 11.0 7.7 6.8 11.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Metallophos PF00149.28 GAX22758.1 - 3.9e-28 99.4 0.0 4.9e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GAS PF13851.6 GAX22759.1 - 0.0044 16.4 4.5 0.0061 15.9 4.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CemA PF03040.14 GAX22759.1 - 0.014 15.3 0.9 0.019 14.9 0.9 1.1 1 0 0 1 1 1 0 CemA family DUF745 PF05335.13 GAX22759.1 - 0.095 12.4 5.2 1 9.1 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF948 PF06103.11 GAX22759.1 - 0.31 11.3 4.8 0.74 10.1 2.4 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TBCA PF02970.16 GAX22760.1 - 0.0079 16.5 0.1 2.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor A Aminotran_4 PF01063.19 GAX22762.1 - 1.4e-44 152.6 0.1 2.1e-44 152.0 0.1 1.3 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_hydro_10 PF00331.20 GAX22763.1 - 2.4e-63 214.2 0.0 2.9e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Remorin_C PF03763.13 GAX22764.1 - 0.19 11.6 5.4 0.19 11.6 2.2 2.0 1 1 1 2 2 2 0 Remorin, C-terminal region YtxH PF12732.7 GAX22764.1 - 1.6 9.3 5.5 2.3 8.8 1.8 2.1 2 0 0 2 2 2 0 YtxH-like protein Leo1 PF04004.13 GAX22765.1 - 1.4e-35 122.6 0.0 1.4e-35 122.6 0.0 2.5 3 0 0 3 3 3 1 Leo1-like protein BUD22 PF09073.10 GAX22765.1 - 6.1 6.1 34.8 0.77 9.0 23.1 2.2 2 0 0 2 2 2 0 BUD22 PCMT PF01135.19 GAX22766.1 - 1.1e-24 87.4 0.0 1.6e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_3_Rpc31 PF11705.8 GAX22766.1 - 0.012 15.9 7.2 0.018 15.3 7.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Fibrillarin PF01269.17 GAX22766.1 - 0.19 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin FH2 PF02181.23 GAX22766.1 - 0.42 9.7 3.7 0.62 9.1 3.7 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Cwf_Cwc_15 PF04889.12 GAX22766.1 - 1.4 8.6 20.3 2 8.1 20.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAX22766.1 - 2.4 7.4 12.2 3.5 6.9 12.2 1.1 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 GAX22766.1 - 3.2 6.7 12.5 4.4 6.2 12.5 1.2 1 0 0 1 1 1 0 Pes-10 V_ATPase_I PF01496.19 GAX22766.1 - 3.3 5.5 3.5 4.5 5.1 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRN3 PF05327.11 GAX22766.1 - 5.1 5.5 11.3 7 5.1 11.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FUSC PF04632.12 GAX22766.1 - 7.2 5.0 7.6 10 4.5 7.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DNA_pol_phi PF04931.13 GAX22766.1 - 9.3 4.2 16.9 14 3.6 16.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi LRR_6 PF13516.6 GAX22767.1 - 0.0017 18.3 14.4 0.79 9.9 0.0 5.5 5 0 0 5 5 5 3 Leucine Rich repeat DUF3336 PF11815.8 GAX22768.1 - 1e-23 83.6 0.0 3.3e-23 81.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAX22768.1 - 1.2e-14 55.0 1.6 1.2e-13 51.8 1.6 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase Peptidase_M41 PF01434.18 GAX22769.1 - 2.4e-61 206.9 1.1 4.5e-61 206.0 1.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAX22769.1 - 1.8e-40 138.4 0.0 5.6e-40 136.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX22769.1 - 4.1e-07 29.7 0.0 9e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAX22769.1 - 4.7e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAX22769.1 - 0.00012 21.4 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 GAX22769.1 - 0.00029 20.9 0.1 0.0012 18.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX22769.1 - 0.00038 20.7 3.7 0.064 13.5 0.5 3.7 2 2 1 3 3 3 1 AAA domain AAA_16 PF13191.6 GAX22769.1 - 0.00041 20.8 0.2 0.00041 20.8 0.2 3.4 3 2 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 GAX22769.1 - 0.0015 19.1 0.0 0.023 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAX22769.1 - 0.0017 18.4 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAX22769.1 - 0.0031 17.2 0.1 0.0088 15.8 0.0 2.0 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 GAX22769.1 - 0.011 16.0 0.2 0.045 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAX22769.1 - 0.016 15.6 0.0 0.051 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAX22769.1 - 0.018 14.5 0.2 0.036 13.5 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX22769.1 - 0.032 14.4 0.5 0.2 11.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 GAX22769.1 - 0.035 14.1 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAX22769.1 - 0.042 13.5 0.2 0.42 10.3 0.0 2.6 2 1 1 4 4 4 0 Sigma-54 interaction domain AAA_2 PF07724.14 GAX22769.1 - 0.045 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 GAX22769.1 - 0.059 12.7 0.2 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 KaiC Peptidase_M50B PF13398.6 GAX22769.1 - 0.085 12.5 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Parvo_NS1 PF01057.17 GAX22769.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 GAX22769.1 - 0.14 11.7 1.2 0.98 9.0 0.4 2.5 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 GAX22769.1 - 0.23 11.4 2.3 0.44 10.5 0.0 2.5 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 GAX22769.1 - 1.4 9.4 4.6 1.1 9.7 0.3 2.5 2 0 0 2 2 2 0 ABC transporter FKBP_C PF00254.28 GAX22770.1 - 3.9e-32 110.4 0.0 4.6e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 GAX22771.1 - 6.5e-33 112.9 0.0 7.6e-33 112.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sedlin_N PF04628.13 GAX22772.1 - 3.2e-36 124.3 0.6 3.6e-36 124.2 0.6 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAX22772.1 - 5.4e-09 36.1 0.3 8e-09 35.6 0.3 1.2 1 1 0 1 1 1 1 Sybindin-like family ATP-synt_F PF01990.17 GAX22774.1 - 5.7e-33 113.1 0.1 8.1e-33 112.6 0.1 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Tropomyosin_1 PF12718.7 GAX22776.1 - 0.0021 18.2 7.3 0.0033 17.6 7.3 1.3 1 0 0 1 1 1 1 Tropomyosin like DUF501 PF04417.12 GAX22776.1 - 0.11 12.3 1.4 0.2 11.5 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF3783 PF12646.7 GAX22776.1 - 0.15 12.1 0.3 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Q_salvage PF10343.9 GAX22777.1 - 6.6e-62 209.6 0.3 9.9e-62 209.1 0.3 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 GAX22777.1 - 8.1e-05 21.5 0.1 0.00036 19.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1688) EnY2 PF10163.9 GAX22777.1 - 0.024 15.0 1.7 0.041 14.3 0.6 2.0 2 0 0 2 2 2 0 Transcription factor e(y)2 CHASE6_C PF17150.4 GAX22777.1 - 0.11 13.2 1.8 0.21 12.2 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain YqzH PF14164.6 GAX22777.1 - 0.26 11.4 1.0 0.54 10.4 1.0 1.5 1 0 0 1 1 1 0 YqzH-like protein Phage_NinH PF06322.11 GAX22780.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Phage NinH protein PNTB PF02233.16 GAX22781.1 - 2.5e-167 557.5 22.4 2.5e-167 557.5 22.4 2.9 3 0 0 3 3 3 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAX22781.1 - 6.8e-59 198.7 0.1 1.8e-58 197.4 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAX22781.1 - 1.1e-32 113.2 0.2 3e-32 111.8 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAX22781.1 - 1e-25 90.0 4.1 1e-25 90.0 4.1 4.3 3 1 1 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 GAX22781.1 - 0.0018 17.6 0.1 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAX22781.1 - 0.0025 17.8 0.2 0.011 15.8 0.2 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.22 GAX22781.1 - 0.018 14.8 0.2 0.15 11.8 0.2 2.6 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.6 GAX22781.1 - 0.021 15.1 0.6 0.021 15.1 0.6 2.9 2 1 1 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX22781.1 - 0.028 13.7 0.1 0.067 12.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase POR_N PF01855.19 GAX22782.1 - 1.9e-69 233.9 0.2 2.9e-69 233.4 0.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.20 GAX22782.1 - 1.4e-27 96.7 0.0 2.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX22782.1 - 3.4e-22 79.2 0.1 7.4e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin POR PF01558.18 GAX22782.1 - 5.9e-17 62.3 0.0 1.1e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 GAX22782.1 - 3.2e-11 43.8 0.0 2.7e-10 40.9 0.0 2.6 3 0 0 3 3 2 1 Oxidoreductase NAD-binding domain EKR PF10371.9 GAX22782.1 - 1.4e-09 37.6 0.0 5.1e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function Fer4_16 PF13484.6 GAX22782.1 - 4.1e-08 34.0 7.3 1.5e-07 32.3 7.3 2.1 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 GAX22782.1 - 5.5e-08 33.3 7.6 1.9e-07 31.6 7.6 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 GAX22782.1 - 4.7e-07 29.4 20.1 0.00016 21.4 1.8 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 GAX22782.1 - 6.4e-06 26.2 12.3 9.7e-06 25.7 10.0 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 GAX22782.1 - 2.1e-05 24.4 0.1 5.9e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_10 PF13237.6 GAX22782.1 - 2.7e-05 24.2 12.7 3e-05 24.0 10.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAX22782.1 - 2.8e-05 24.5 5.1 9e-05 22.8 5.1 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAX22782.1 - 3.4e-05 23.7 22.7 0.00013 21.9 2.9 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain PFOR_II PF17147.4 GAX22782.1 - 5.4e-05 23.4 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_17 PF13534.6 GAX22782.1 - 0.00013 22.4 8.0 0.00071 20.1 7.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 GAX22782.1 - 0.00032 20.8 12.2 0.0072 16.4 12.1 2.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAX22782.1 - 0.002 18.1 20.8 0.013 15.6 2.4 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 GAX22782.1 - 0.012 16.5 19.1 0.04 14.9 5.3 3.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 GAX22782.1 - 0.023 15.2 15.6 0.2 12.2 1.2 3.2 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 GAX22782.1 - 0.079 13.2 10.4 0.49 10.6 5.2 3.3 2 2 2 4 4 4 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 GAX22782.1 - 2.2 9.1 7.6 4.9 8.0 1.5 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain FluMu_N PF17891.1 GAX22786.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Pox_F15 PF04596.12 GAX22787.1 - 0.12 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus protein F15 FA_desaturase PF00487.24 GAX22788.1 - 5.3e-23 82.2 27.6 9.9e-23 81.3 27.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 GAX22788.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) TP53IP5 PF15331.6 GAX22789.1 - 0.32 11.1 0.1 0.32 11.1 0.1 2.3 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Tyr-DNA_phospho PF06087.12 GAX22790.1 - 7.3e-69 232.7 0.0 8.8e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase IQ PF00612.27 GAX22791.1 - 0.0079 15.9 0.9 0.021 14.6 0.9 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif BTB PF00651.31 GAX22792.1 - 9.8e-13 48.3 0.2 2.3e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAX22793.1 - 1.1e-13 51.4 0.4 5.3e-13 49.2 0.1 2.2 2 1 0 2 2 2 1 BTB/POZ domain Cytochrome_CBB3 PF13442.6 GAX22794.1 - 1.1e-17 64.0 0.2 1.7e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAX22794.1 - 2.3e-09 37.1 0.1 4.7e-07 29.6 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c-550 domain Cytochrom_C PF00034.21 GAX22794.1 - 4.9e-09 37.2 0.9 1.4e-08 35.8 0.9 1.7 1 1 0 1 1 1 1 Cytochrome c 2OG-FeII_Oxy_3 PF13640.6 GAX22795.1 - 1e-05 26.3 0.0 1.8e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily aGPT-Pplase1 PF18723.1 GAX22796.1 - 1.1e-40 139.8 2.9 1.2e-26 93.8 0.2 2.1 2 0 0 2 2 2 2 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 T4BSS_DotI_IcmL PF11393.8 GAX22796.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component Tudor_4 PF18358.1 GAX22796.1 - 0.058 13.0 0.0 0.18 11.4 0.0 1.9 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain TraF PF13728.6 GAX22796.1 - 0.17 11.7 0.1 0.26 11.1 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein zf-RING_5 PF14634.6 GAX22796.1 - 0.42 10.6 19.8 0.13 12.3 11.1 2.9 3 0 0 3 3 3 0 zinc-RING finger domain PHD PF00628.29 GAX22796.1 - 1.5 8.8 15.3 0.64 10.0 11.8 2.2 2 0 0 2 2 2 0 PHD-finger Helicase_C PF00271.31 GAX22797.1 - 1.5e-14 54.3 0.0 3.3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX22797.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 GAX22797.1 - 3.7e-05 24.0 0.0 0.00015 22.0 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) XPG_I_2 PF12813.7 GAX22797.1 - 0.0073 15.8 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing DUF2480 PF10652.9 GAX22798.1 - 0.09 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) DEP PF00610.21 GAX22798.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TssO PF17561.2 GAX22798.1 - 0.15 12.1 0.0 0.15 12.1 0.0 2.7 4 0 0 4 4 4 0 Type VI secretion system, TssO DUF3602 PF12223.8 GAX22799.1 - 0.31 11.7 0.0 0.31 11.7 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3602) PC-Esterase PF13839.6 GAX22800.1 - 1e-05 25.4 0.1 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Eno-Rase_NADH_b PF12242.8 GAX22800.1 - 0.095 12.5 0.0 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pirin PF02678.16 GAX22801.1 - 4.5e-30 103.8 0.4 7.1e-30 103.2 0.4 1.2 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 GAX22801.1 - 5.5e-15 55.3 0.0 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 GAX22801.1 - 2.1e-07 30.6 0.2 7.6e-07 28.8 0.1 2.0 2 0 0 2 2 2 1 Cupin domain S4 PF01479.25 GAX22801.1 - 0.0094 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 1 S4 domain Pirin_C PF05726.13 GAX22801.1 - 0.015 15.6 0.0 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Pirin C-terminal cupin domain Amino_oxidase PF01593.24 GAX22802.1 - 8.7e-46 157.1 0.0 2.1e-45 155.9 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX22802.1 - 4.6e-09 36.4 0.2 1.4e-08 34.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAX22802.1 - 0.00019 21.5 0.1 0.0019 18.2 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 GAX22802.1 - 0.0016 18.1 0.0 0.0037 16.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX22802.1 - 0.0046 16.2 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAX22802.1 - 0.022 13.6 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 GAX22802.1 - 0.036 14.6 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX22802.1 - 0.041 12.6 0.0 0.074 11.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 GAX22802.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 GAX22802.1 - 0.22 10.7 0.1 0.34 10.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Annexin PF00191.20 GAX22803.1 - 1.6e-45 153.0 3.4 3.6e-12 46.2 0.0 4.2 4 0 0 4 4 4 4 Annexin Mob_Pre PF01076.19 GAX22803.1 - 0.011 15.5 0.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Plasmid recombination enzyme YlbE PF14003.6 GAX22803.1 - 0.075 13.5 0.1 17 6.0 0.0 3.4 3 0 0 3 3 3 0 YlbE-like protein Lipase_GDSL_2 PF13472.6 GAX22804.1 - 5.1e-14 53.1 0.0 1e-13 52.1 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX22804.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase UPF0054 PF02130.17 GAX22805.1 - 5.8e-26 90.8 0.5 4e-25 88.1 0.5 2.0 1 1 0 1 1 1 1 Uncharacterized protein family UPF0054 SPT2 PF08243.11 GAX22805.1 - 0.051 14.1 6.5 0.091 13.3 6.5 1.3 1 0 0 1 1 1 0 SPT2 chromatin protein Pkinase PF00069.25 GAX22806.1 - 1.1e-07 31.5 0.0 3.8e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22806.1 - 0.00017 21.0 0.0 0.001 18.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 GAX22807.1 - 5.4e-34 117.6 0.0 1.2e-33 116.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX22807.1 - 1.8e-30 106.2 0.0 2.8e-30 105.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX22807.1 - 0.00044 19.2 0.0 0.00094 18.1 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAX22807.1 - 0.099 12.2 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 GAX22807.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 GAX22808.1 - 2.7e-17 63.1 0.0 6.7e-06 26.6 0.0 5.9 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAX22808.1 - 4.1e-12 46.0 9.7 0.047 14.1 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 GAX22808.1 - 1.4e-10 40.4 7.1 1.4 9.7 0.0 9.0 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 GAX22808.1 - 1e-08 35.3 0.2 0.055 13.8 0.0 6.9 7 1 1 8 8 8 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX22808.1 - 4.2e-08 33.6 2.9 3.4 8.3 0.0 6.7 5 3 0 7 7 7 3 Ankyrin repeats (many copies) TPR_1 PF00515.28 GAX22809.1 - 6e-44 146.1 42.7 1.9e-06 27.4 0.1 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAX22809.1 - 4.1e-40 132.7 37.2 9.5e-06 25.4 0.3 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 GAX22809.1 - 2e-31 107.4 32.4 4.8e-09 35.7 0.4 9.3 4 3 5 10 10 10 6 TPR repeat STI1 PF17830.1 GAX22809.1 - 5e-28 96.8 21.5 5.5e-14 51.8 3.5 3.0 3 0 0 3 3 2 2 STI1 domain TPR_14 PF13428.6 GAX22809.1 - 8.2e-25 85.4 18.2 0.015 16.1 0.7 9.0 5 3 4 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAX22809.1 - 1.9e-24 83.8 33.4 0.002 18.2 2.3 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAX22809.1 - 9.6e-22 77.4 20.8 1.2e-05 25.9 1.8 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAX22809.1 - 1.4e-18 67.2 23.7 0.00019 21.9 0.2 6.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAX22809.1 - 3e-17 62.7 23.9 2.4e-06 27.7 0.9 6.5 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAX22809.1 - 1.9e-15 56.0 21.2 0.0015 18.7 0.1 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAX22809.1 - 1.7e-10 40.9 4.9 0.059 13.5 0.1 5.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX22809.1 - 9.3e-09 34.7 14.9 0.39 10.8 0.3 6.8 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX22809.1 - 1.2e-05 25.4 24.4 0.014 15.6 1.3 5.7 3 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAX22809.1 - 0.00018 21.3 29.7 0.16 11.9 1.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat XPC-binding PF09280.11 GAX22809.1 - 0.00035 20.2 11.3 0.007 16.1 1.8 2.5 2 0 0 2 2 2 2 XPC-binding domain TPR_3 PF07720.12 GAX22809.1 - 0.0064 16.5 17.4 0.99 9.5 0.3 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX22809.1 - 0.063 13.4 8.0 22 5.2 0.0 5.5 6 1 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 GAX22809.1 - 0.069 13.5 0.5 0.069 13.5 0.5 5.3 3 3 4 7 7 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX22809.1 - 0.19 11.2 7.5 0.82 9.2 0.0 4.1 4 0 0 4 4 4 0 SHNi-TPR DUF357 PF04010.13 GAX22809.1 - 0.2 11.8 7.6 0.14 12.2 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF357) TPR_6 PF13174.6 GAX22809.1 - 0.47 11.2 26.1 1.3 9.8 0.4 6.7 8 0 0 8 8 5 0 Tetratricopeptide repeat HTH_33 PF13592.6 GAX22809.1 - 0.62 9.7 4.0 4.3 7.1 0.1 3.3 3 0 0 3 3 3 0 Winged helix-turn helix Alkyl_sulf_dimr PF14863.6 GAX22809.1 - 0.84 10.1 15.6 12 6.4 1.9 3.8 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation BTAD PF03704.17 GAX22809.1 - 1.7 9.0 22.1 19 5.7 0.1 5.7 4 1 2 6 6 6 0 Bacterial transcriptional activator domain MIT PF04212.18 GAX22809.1 - 9.8 6.3 33.4 28 4.9 0.0 8.1 5 1 2 7 7 6 0 MIT (microtubule interacting and transport) domain Xpo1 PF08389.12 GAX22810.1 - 9.4e-06 25.8 7.1 3.7e-05 23.8 0.4 4.7 3 3 2 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 GAX22810.1 - 1.4e-05 24.9 0.1 4.2e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.11 GAX22810.1 - 0.015 14.5 0.1 0.042 13.0 0.1 1.7 1 0 0 1 1 1 0 CRM1 C terminal CRM1_repeat PF18777.1 GAX22810.1 - 0.024 14.1 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat UAA PF08449.11 GAX22811.1 - 5.4e-41 140.8 13.0 8.7e-41 140.1 13.0 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX22811.1 - 8.3e-08 32.5 26.5 1.1e-05 25.6 13.8 2.8 2 1 1 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 GAX22811.1 - 0.0012 17.9 2.5 0.0012 17.9 2.5 2.2 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 GAX22811.1 - 0.007 15.8 10.0 0.16 11.3 0.6 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family DNA_pol3_tau_5 PF12170.8 GAX22811.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha DAGAT PF03982.13 GAX22812.1 - 6.4e-15 54.8 0.0 8.6e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase AIM24 PF01987.17 GAX22813.1 - 7.4e-59 198.9 0.7 9.5e-59 198.6 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 dCMP_cyt_deam_1 PF00383.23 GAX22814.1 - 1.9e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Dala_Dala_lig_C PF07478.13 GAX22815.1 - 1e-17 64.4 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 GAX22815.1 - 1e-12 48.8 0.0 6.7e-11 42.9 0.0 2.8 2 1 0 2 2 2 1 SET domain LacAB_rpiB PF02502.18 GAX22815.1 - 0.044 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase CCDC106 PF15794.5 GAX22816.1 - 4.7e-06 26.5 7.2 1.1e-05 25.3 7.2 1.7 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 DUF4763 PF15960.5 GAX22816.1 - 0.13 11.5 5.5 0.53 9.5 5.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1664 PF07889.12 GAX22816.1 - 0.49 10.4 8.4 2.3 8.3 1.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 GAX22816.1 - 1.5 8.8 20.3 0.92 9.5 8.6 3.5 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 GAX22816.1 - 4.6 6.5 19.3 0.38 10.1 11.1 2.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 GAX22816.1 - 5 7.0 7.3 2 8.3 3.8 2.3 2 0 0 2 2 2 0 Septum formation initiator Z1 PF10593.9 GAX22816.1 - 5.7 6.4 8.8 8.3 5.8 0.1 2.9 3 0 0 3 3 3 0 Z1 domain VPS11_C PF12451.8 GAX22817.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Pkinase PF00069.25 GAX22818.1 - 1.9e-21 76.6 0.0 3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 GAX22818.1 - 1.8e-10 41.3 2.0 6.7e-08 33.0 0.0 2.9 2 1 1 3 3 3 2 Adenylate sensor of SNF1-like protein kinase KA1 PF02149.19 GAX22818.1 - 7.9e-08 32.0 0.0 2.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase_Tyr PF07714.17 GAX22818.1 - 1.6e-05 24.3 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX22818.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.20 GAX22819.1 - 3.4e-99 332.8 0.4 5.1e-99 332.2 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAX22819.1 - 3.9e-17 62.8 2.1 3.9e-15 56.3 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX22819.1 - 1.2e-08 34.4 0.2 0.35 11.2 0.1 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 GAX22819.1 - 1e-05 25.8 1.0 1.3 9.5 0.0 4.7 4 1 2 6 6 6 4 HEAT repeats RTP1_C1 PF10363.9 GAX22819.1 - 0.00044 20.4 0.2 1.9 8.7 0.0 3.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 GAX22819.1 - 0.0062 16.9 0.3 6.6 7.2 0.0 3.0 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cohesin_HEAT PF12765.7 GAX22819.1 - 0.021 15.1 0.2 0.39 11.1 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion NAD_binding_8 PF13450.6 GAX22820.1 - 1.4e-12 47.7 0.0 4.6e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAX22820.1 - 1.5e-12 47.6 0.0 2.9e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAX22820.1 - 9.2e-09 34.9 1.2 6.1e-05 22.3 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX22820.1 - 7.8e-07 29.0 0.2 0.0059 16.2 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase GDI PF00996.18 GAX22820.1 - 1.9e-06 26.7 0.2 0.0036 15.9 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Pyr_redox_2 PF07992.14 GAX22820.1 - 1.6e-05 24.3 0.6 0.0053 16.0 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX22820.1 - 0.00014 21.1 0.5 0.00028 20.2 0.5 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAX22820.1 - 0.00021 20.5 1.3 0.41 9.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 GAX22820.1 - 0.00023 20.0 1.6 0.019 13.7 0.5 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 GAX22820.1 - 0.00058 19.3 1.3 0.00084 18.8 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX22820.1 - 0.0088 16.6 1.0 2.2 8.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 GAX22820.1 - 0.066 12.6 0.0 0.34 10.3 0.0 2.2 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Pyr_redox_3 PF13738.6 GAX22820.1 - 0.12 11.6 0.4 0.32 10.2 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX22820.1 - 0.16 11.2 2.0 0.17 11.1 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain CAP18_C PF12153.8 GAX22820.1 - 0.28 11.1 1.0 0.53 10.2 1.0 1.4 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) DUF4502 PF14950.6 GAX22821.1 - 0.096 12.1 0.9 0.14 11.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) DENN PF02141.21 GAX22822.1 - 5e-41 140.7 2.4 5e-41 140.7 2.4 2.7 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 GAX22822.1 - 2.6e-09 37.7 1.3 2.6e-09 37.7 1.3 2.7 3 0 0 3 3 3 1 uDENN domain dDENN PF03455.19 GAX22822.1 - 5.4e-05 23.1 0.5 0.00028 20.8 0.2 2.5 1 1 0 1 1 1 1 dDENN domain ArfGap PF01412.18 GAX22822.1 - 0.0021 18.1 0.1 2 8.5 0.0 3.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf IQ PF00612.27 GAX22822.1 - 0.017 14.9 1.0 0.017 14.9 1.0 3.9 4 0 0 4 4 4 0 IQ calmodulin-binding motif His_Phos_1 PF00300.22 GAX22823.1 - 4.1e-30 104.9 1.0 5.1e-23 81.8 0.7 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ebp2 PF05890.12 GAX22824.1 - 3.3e-51 174.4 23.5 3.3e-51 174.4 23.5 2.4 1 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 AA_kinase PF00696.28 GAX22825.1 - 2.8e-47 161.4 2.4 3.3e-47 161.1 2.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family Methyltransf_21 PF05050.12 GAX22826.1 - 1.3e-06 28.5 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain eIF-5a PF01287.20 GAX22827.1 - 6.4e-16 58.2 0.1 8.4e-16 57.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Pantoate_transf PF02548.15 GAX22828.1 - 3.6e-104 347.7 0.6 4.8e-104 347.3 0.6 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 GAX22828.1 - 0.0014 18.2 0.1 0.003 17.0 0.1 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 GAX22828.1 - 0.012 15.5 0.0 0.085 12.7 0.0 2.3 3 0 0 3 3 3 0 Asp/Glu/Hydantoin racemase WD40 PF00400.32 GAX22829.1 - 1e-25 89.5 11.0 0.00013 22.6 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 GAX22829.1 - 1.3e-25 89.4 0.9 1.3e-25 89.4 0.9 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 GAX22829.1 - 5.8e-06 26.5 3.5 0.29 11.5 0.6 4.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX22829.1 - 0.016 13.9 3.1 2.7 6.5 0.3 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX22829.1 - 0.016 14.1 0.3 10 5.0 0.0 3.1 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD PF00270.29 GAX22830.1 - 1.2e-15 57.7 0.1 7.9e-15 55.1 0.1 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX22830.1 - 3.4e-10 40.2 0.0 9.3e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 GAX22830.1 - 0.026 13.6 0.1 0.047 12.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 GAX22830.1 - 0.031 14.5 0.4 2.7 8.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAX22830.1 - 0.11 11.7 0.2 16 4.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 GAX22830.1 - 0.13 11.5 1.0 3.7 6.8 0.2 2.2 2 0 0 2 2 2 0 KaiC Pox_A32 PF04665.12 GAX22830.1 - 0.22 10.9 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein PDZ_6 PF17820.1 GAX22831.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX22831.1 - 0.00083 19.7 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX22831.1 - 0.004 17.5 0.0 0.0068 16.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Nucleoporin_FG PF13634.6 GAX22831.1 - 1 10.3 11.6 2.3 9.1 1.0 3.5 3 2 1 4 4 4 0 Nucleoporin FG repeat region AAA_5 PF07728.14 GAX22832.1 - 0.14 12.1 0.2 16 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Leu_zip PF15294.6 GAX22833.1 - 0.0044 16.6 26.1 0.0044 16.6 26.1 9.6 1 1 8 9 9 9 2 Leucine zipper DUF1517 PF07466.11 GAX22834.1 - 1.5e-37 129.5 0.0 1.8e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1517 PF07466.11 GAX22835.1 - 1.1e-38 133.2 0.0 1.3e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) Epimerase PF01370.21 GAX22836.1 - 4.9e-13 49.1 0.0 1.1e-11 44.7 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX22836.1 - 1.4e-07 30.9 0.2 6.8e-06 25.4 0.2 2.9 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAX22836.1 - 1.2e-06 27.7 0.0 0.0087 15.1 0.1 2.6 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAX22836.1 - 1.5e-06 28.2 0.0 2.7e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAX22836.1 - 0.00029 20.1 1.8 0.96 8.6 0.1 3.2 2 1 1 3 3 3 2 Male sterility protein NmrA PF05368.13 GAX22836.1 - 0.00039 20.1 0.0 0.003 17.1 0.0 2.4 2 1 0 2 2 2 1 NmrA-like family PA PF02225.22 GAX22837.1 - 4.4e-09 36.2 0.0 1.9e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 PA domain Phage_holin_2_4 PF16082.5 GAX22837.1 - 0.0054 16.4 0.6 0.013 15.2 0.1 1.8 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like Thioredoxin_4 PF13462.6 GAX22837.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin PA PF02225.22 GAX22838.1 - 6.7e-10 38.9 0.0 2.3e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 PA domain Acetyltransf_10 PF13673.7 GAX22839.1 - 9.1e-14 51.5 0.2 1.2e-13 51.1 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX22839.1 - 1.1e-10 41.8 0.0 1.5e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX22839.1 - 1.7e-10 41.2 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX22839.1 - 1.9e-06 27.8 0.1 3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 GAX22839.1 - 0.0033 17.2 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 GAX22839.1 - 0.0075 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Cwf_Cwc_15 PF04889.12 GAX22840.1 - 0.008 15.9 2.4 0.008 15.9 2.4 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Tub_N PF16322.5 GAX22840.1 - 0.098 13.0 1.1 1.1 9.6 0.2 2.1 2 0 0 2 2 2 0 Tubby N-terminal FAM176 PF14851.6 GAX22840.1 - 0.31 10.7 4.5 2 8.0 1.2 2.3 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 GAX22840.1 - 0.44 10.9 19.1 2.8 8.4 0.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 GAX22840.1 - 0.96 9.9 19.5 1.9 8.9 0.5 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 GAX22840.1 - 1.9 8.5 8.6 2.6 8.0 4.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 GAX22840.1 - 2 8.2 6.5 17 5.2 2.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 GAX22840.1 - 9.4 5.7 10.1 1.3 8.5 2.5 2.1 2 0 0 2 2 2 0 PPP4R2 DUF2457 PF10446.9 GAX22840.1 - 9.9 5.2 15.0 0.62 9.2 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TGT PF01702.18 GAX22841.1 - 6.9e-97 324.7 0.0 3.9e-95 319.0 0.0 2.1 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF3439 PF11921.8 GAX22841.1 - 0.0018 18.3 13.3 0.0037 17.2 13.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Med13_C PF06333.12 GAX22841.1 - 0.2 10.9 6.6 0.3 10.3 6.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Dicty_REP PF05086.12 GAX22841.1 - 0.33 8.9 7.7 0.43 8.5 7.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.6 GAX22841.1 - 1.6 8.9 14.8 3.4 7.9 14.8 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus FSA_C PF10479.9 GAX22841.1 - 3.2 5.8 12.0 4.9 5.2 12.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 GAX22841.1 - 6.3 6.8 35.2 11 6.0 35.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein HAD_2 PF13419.6 GAX22843.1 - 2.4e-25 89.6 0.0 5.5e-25 88.5 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX22843.1 - 1.6e-19 71.1 0.0 1.1e-15 58.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX22843.1 - 2.9e-05 24.0 0.0 7.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GAX22843.1 - 0.00073 20.0 0.0 0.0016 18.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAX22843.1 - 0.056 13.6 0.1 0.93 9.6 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PhyH PF05721.13 GAX22844.1 - 2.2e-06 28.1 1.0 4.4e-06 27.1 0.4 1.9 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Csc2 PF18320.1 GAX22844.1 - 0.07 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Csc2 Crispr Sep15_SelM PF08806.11 GAX22845.1 - 0.16 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Sep15/SelM redox domain Band_7 PF01145.25 GAX22846.1 - 9.7e-27 94.1 2.5 1.4e-26 93.6 1.0 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.8 GAX22846.1 - 0.08 13.1 0.6 0.14 12.4 0.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 MRP-S27 PF10037.9 GAX22846.1 - 0.082 11.8 1.5 0.12 11.2 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF1104 PF06518.11 GAX22846.1 - 1.3 9.5 5.5 8.3 6.9 4.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) PNPase_C PF12111.8 GAX22848.1 - 1.1 8.8 4.8 2.2 7.8 4.8 1.4 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal FG-GAP_2 PF14312.6 GAX22849.1 - 1e-13 51.3 24.4 0.00016 21.9 0.3 6.0 6 0 0 6 6 6 5 FG-GAP repeat FG-GAP_2 PF14312.6 GAX22850.1 - 1.1e-23 83.2 54.1 0.0022 18.2 0.5 11.4 11 0 0 11 11 11 9 FG-GAP repeat WW PF00397.26 GAX22850.1 - 5.3e-12 45.6 2.5 5.3e-12 45.6 2.5 1.9 2 0 0 2 2 2 1 WW domain Glyco_hyd_101C PF17451.2 GAX22850.1 - 0.048 13.9 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain ubiquitin PF00240.23 GAX22851.1 - 1.6e-08 34.2 0.5 4e-08 32.9 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 GAX22851.1 - 0.00018 21.9 0.1 0.00032 21.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX22851.1 - 0.0038 17.2 0.7 0.45 10.6 0.7 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Glyoxalase_4 PF13669.6 GAX22851.1 - 0.0074 16.5 0.0 0.0082 16.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YukD PF08817.10 GAX22851.1 - 0.016 15.9 0.0 0.021 15.5 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD UCH_N PF16674.5 GAX22851.1 - 0.1 12.5 0.3 0.13 12.2 0.3 1.4 1 1 0 1 1 1 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 NAC PF01849.18 GAX22852.1 - 2e-22 78.9 0.6 4.4e-22 77.8 0.6 1.6 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 GAX22852.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Cpn60_TCP1 PF00118.24 GAX22854.1 - 2.5e-148 494.8 3.0 9.1e-148 492.9 3.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRRFIP PF09738.9 GAX22855.1 - 0.0072 15.8 11.3 0.013 15.0 10.8 1.5 1 1 0 1 1 1 1 LRRFIP family Telomere_reg-2 PF10193.9 GAX22855.1 - 0.024 15.1 0.7 0.035 14.5 0.7 1.3 1 0 0 1 1 1 0 Telomere length regulation protein FAM76 PF16046.5 GAX22855.1 - 0.067 12.5 9.1 0.066 12.6 8.1 1.5 1 1 1 2 2 2 0 FAM76 protein MPS2 PF17060.5 GAX22855.1 - 0.11 11.8 4.3 0.12 11.6 4.3 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Atg14 PF10186.9 GAX22855.1 - 0.27 10.3 5.6 0.36 9.9 5.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5394 PF17372.2 GAX22855.1 - 0.63 9.5 6.7 0.86 9.1 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5394) ZapB PF06005.12 GAX22855.1 - 2.3 8.7 15.2 3.2 8.3 13.2 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Peptidase_M50B PF13398.6 GAX22856.1 - 2.5e-48 164.4 11.7 3e-48 164.1 11.7 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 GAX22856.1 - 0.45 9.7 4.0 0.31 10.3 1.0 2.0 1 1 1 2 2 2 0 Peptidase family M50 Tfb2 PF03849.14 GAX22858.1 - 1.4e-81 274.3 0.0 1.6e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GAX22858.1 - 2.6e-10 40.6 2.1 6.2e-10 39.4 2.1 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 GAX22858.1 - 4.7e-05 23.5 0.0 0.0026 17.9 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain SQS_PSY PF00494.19 GAX22858.1 - 0.038 13.5 0.0 0.098 12.1 0.0 1.7 1 0 0 1 1 1 0 Squalene/phytoene synthase AA_permease_2 PF13520.6 GAX22859.1 - 9.1e-34 117.0 27.9 9.1e-34 117.0 27.9 1.4 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAX22859.1 - 1.3e-22 80.1 26.6 2.5e-22 79.1 26.5 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GAX22859.1 - 2.1e-06 27.7 7.9 2.1e-06 27.7 7.9 3.7 5 0 0 5 5 5 1 C-terminus of AA_permease UPF0242 PF06785.11 GAX22859.1 - 0.045 13.9 1.8 9.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus bPH_2 PF03703.14 GAX22860.1 - 2.7e-12 46.7 0.1 3.9e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial PH domain DUF1205 PF06722.12 GAX22860.1 - 0.049 13.7 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) bPH_3 PF14470.6 GAX22860.1 - 0.061 13.7 0.0 0.092 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain Ank_2 PF12796.7 GAX22861.1 - 1.2e-34 118.7 0.4 5.7e-09 36.4 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX22861.1 - 1.3e-27 95.8 8.0 4.5e-08 33.5 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX22861.1 - 1.4e-25 89.0 9.9 2.1e-06 27.9 0.0 8.1 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX22861.1 - 5.8e-23 78.5 12.7 0.069 13.7 0.0 10.3 11 0 0 11 11 11 8 Ankyrin repeat Ank PF00023.30 GAX22861.1 - 4.7e-21 74.2 5.8 0.046 14.2 0.0 9.5 8 2 1 9 9 9 6 Ankyrin repeat ThiC-associated PF13667.6 GAX22861.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 ThiC-associated domain TPR_12 PF13424.6 GAX22862.1 - 7.8e-25 87.0 0.6 4.6e-10 39.6 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX22862.1 - 1.4e-12 47.0 0.0 0.0035 17.2 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX22862.1 - 1.4e-09 37.3 1.1 0.064 13.4 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX22862.1 - 3.2e-08 33.0 0.7 0.95 9.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX22862.1 - 1.5e-05 24.8 0.2 0.26 11.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX22862.1 - 6e-05 22.8 0.1 6.2 7.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX22862.1 - 0.0016 19.1 0.5 36 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX22862.1 - 0.0022 18.5 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX22862.1 - 0.041 14.3 1.1 59 4.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX22862.1 - 0.072 13.7 1.4 1e+02 3.6 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat BING4CT PF08149.11 GAX22864.1 - 6.3e-31 106.0 0.0 8.5e-30 102.4 0.0 2.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 GAX22864.1 - 4.5e-08 33.6 0.0 0.00026 21.7 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX22864.1 - 0.00067 19.9 0.2 4.5 7.6 0.0 4.9 3 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PGM_PMM_I PF02878.16 GAX22865.1 - 5.3e-20 71.5 0.0 1.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 GAX22865.1 - 1.3e-19 70.8 0.0 3.2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAX22865.1 - 6.9e-12 45.6 0.1 1.2e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Diphthamide_syn PF01866.17 GAX22866.1 - 0.093 12.2 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein IstB_IS21_ATP PF08483.11 GAX22866.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal Cwf_Cwc_15 PF04889.12 GAX22867.1 - 0.002 17.9 4.5 0.0028 17.4 4.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GST_C PF00043.25 GAX22867.1 - 0.013 15.7 0.1 0.037 14.3 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Vfa1 PF08432.10 GAX22867.1 - 0.041 14.2 0.7 0.056 13.8 0.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.12 GAX22867.1 - 0.31 10.3 3.4 0.39 10.0 3.4 1.2 1 0 0 1 1 1 0 NOA36 protein SOR_SNZ PF01680.17 GAX22868.1 - 2.8e-100 334.3 7.7 4.4e-100 333.6 7.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 GAX22868.1 - 1.4e-07 31.1 6.9 6.8e-07 28.9 0.4 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 GAX22868.1 - 2.5e-05 23.5 0.2 0.021 13.9 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GAX22868.1 - 0.00057 19.4 0.1 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 GAX22868.1 - 0.0036 17.3 0.0 0.0095 16.0 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 GAX22868.1 - 0.0055 16.1 4.0 0.017 14.5 0.3 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase OMPdecase PF00215.24 GAX22868.1 - 0.0077 15.8 0.1 1.9 8.0 0.0 2.3 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family NanE PF04131.14 GAX22868.1 - 0.011 15.0 2.0 0.033 13.4 0.1 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 GAX22868.1 - 0.022 13.7 0.2 0.031 13.3 0.2 1.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 GAX22868.1 - 0.032 13.4 0.2 0.15 11.2 0.0 2.1 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase Carb_anhydrase PF00194.21 GAX22869.1 - 6.8e-26 91.3 0.5 3.3e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Exostosin PF03016.15 GAX22870.1 - 4e-16 59.1 0.7 7.2e-16 58.3 0.7 1.4 1 1 0 1 1 1 1 Exostosin family DUF4490 PF14892.6 GAX22870.1 - 0.035 14.2 0.1 0.077 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) Rtt106 PF08512.12 GAX22871.1 - 4.8e-15 55.7 0.0 8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like ORC6 PF05460.13 GAX22871.1 - 0.25 10.6 3.5 0.36 10.1 3.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CHCH PF06747.13 GAX22872.1 - 0.00054 20.0 3.4 0.00078 19.5 3.4 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 GAX22872.1 - 0.0013 19.0 2.9 0.0019 18.4 2.9 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 GAX22872.1 - 0.012 15.6 1.3 0.015 15.3 1.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 GAX22872.1 - 0.15 12.1 3.2 0.23 11.5 3.2 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pkinase PF00069.25 GAX22873.1 - 4.7e-26 91.7 0.0 7.7e-26 91.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX22873.1 - 1.9e-10 40.4 0.0 3.5e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RdRP PF05183.12 GAX22873.1 - 0.073 11.7 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase APH PF01636.23 GAX22873.1 - 0.094 12.6 0.9 0.21 11.5 0.2 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family RNA_pol_Rpb6 PF01192.22 GAX22874.1 - 6.2e-17 61.3 0.3 1.2e-16 60.3 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF1336 PF07059.12 GAX22875.1 - 2.8e-51 174.8 0.0 4.5e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) OSCP PF00213.18 GAX22875.1 - 0.049 13.8 0.2 0.15 12.2 0.4 1.7 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit UQ_con PF00179.26 GAX22876.1 - 5.7e-37 126.5 0.0 8.2e-37 126.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX22876.1 - 0.0026 18.0 0.0 0.003 17.8 0.0 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 GAX22876.1 - 0.034 14.0 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 GAX22876.1 - 0.092 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B TPR_2 PF07719.17 GAX22877.1 - 1.3e-18 65.5 3.4 5.8e-07 29.2 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX22877.1 - 5.9e-17 60.7 1.6 1.4e-06 27.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX22877.1 - 3.9e-14 52.0 5.6 5.9e-09 35.5 0.2 3.3 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 GAX22877.1 - 4.3e-10 39.6 2.0 0.0016 19.1 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.31 GAX22877.1 - 1.1e-09 38.3 1.7 3.8e-09 36.5 0.4 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 GAX22877.1 - 7.9e-09 35.9 3.0 1.1e-05 25.8 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX22877.1 - 1.6e-08 35.1 6.5 4.9e-05 23.9 1.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX22877.1 - 2.4e-07 30.3 0.8 0.0071 16.3 0.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX22877.1 - 3.1e-07 30.6 10.8 2.8e-05 24.3 1.8 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX22877.1 - 2.8e-06 27.1 2.3 0.016 15.4 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX22877.1 - 7.1e-06 26.1 1.7 0.043 14.0 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX22877.1 - 2e-05 24.3 2.6 0.09 12.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX22877.1 - 3.8e-05 23.8 2.3 0.041 14.3 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX22877.1 - 0.0003 20.8 0.5 0.028 14.5 0.1 3.0 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 GAX22877.1 - 0.00064 20.2 3.1 0.33 11.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 GAX22877.1 - 0.027 14.9 6.7 0.29 11.6 0.1 3.2 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Nuc_sug_transp PF04142.15 GAX22878.1 - 6.2e-59 199.7 21.6 7.6e-59 199.4 21.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAX22878.1 - 1.7e-09 37.3 18.4 2.6e-09 36.7 18.4 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX22878.1 - 2.1e-09 37.6 26.3 8e-05 22.8 9.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX22878.1 - 1.9e-07 30.7 19.6 2.2e-06 27.2 19.6 2.2 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 GAX22878.1 - 0.0003 20.2 18.0 0.00073 19.0 18.0 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF4131 PF13567.6 GAX22878.1 - 0.013 15.1 0.0 0.013 15.1 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) SLATT_1 PF18181.1 GAX22878.1 - 0.33 10.9 1.3 10 6.0 0.0 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 VIT1 PF01988.19 GAX22879.1 - 8.7e-12 45.4 8.2 2e-10 40.9 8.2 2.4 1 1 0 1 1 1 1 VIT family Glyco_hydro_cc PF11790.8 GAX22881.1 - 3.9e-52 177.2 2.3 5.2e-52 176.8 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.13 GAX22881.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 GFO_IDH_MocA PF01408.22 GAX22882.1 - 3e-12 47.4 0.0 2.6e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAX22882.1 - 5.2e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 GAX22882.1 - 0.0072 17.0 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DNA_III_psi PF03603.13 GAX22882.1 - 0.0094 16.2 0.2 0.016 15.5 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase III psi subunit ox_reductase_C PF08635.10 GAX22882.1 - 0.071 12.8 0.0 0.46 10.1 0.0 2.0 1 1 1 2 2 2 0 Putative oxidoreductase C terminal domain Nuc_sug_transp PF04142.15 GAX22883.1 - 3.8e-57 193.8 24.0 4.8e-57 193.5 24.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAX22883.1 - 1.1e-07 32.1 24.3 0.00017 21.8 7.1 2.5 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX22883.1 - 1e-06 28.3 24.1 1.7e-06 27.5 24.1 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 GAX22883.1 - 9.8e-05 21.7 19.7 0.00015 21.0 19.7 1.3 1 0 0 1 1 1 1 UAA transporter family NUDIX PF00293.28 GAX22885.1 - 5.6e-18 65.2 0.1 6.7e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain XPC-binding PF09280.11 GAX22885.1 - 0.12 12.2 2.3 0.18 11.5 2.3 1.3 1 0 0 1 1 1 0 XPC-binding domain SET PF00856.28 GAX22886.1 - 2e-11 44.6 0.0 7.4e-06 26.4 0.0 3.5 2 1 0 2 2 2 2 SET domain MoCF_biosynth PF00994.24 GAX22889.1 - 2.7e-28 98.5 0.0 5.3e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 GAX22889.1 - 2.7e-23 82.9 0.0 2.9e-22 79.5 0.0 2.5 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Asp_Arg_Hydrox PF05118.15 GAX22890.1 - 1.6e-32 112.5 0.0 2.3e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase F1F0-ATPsyn_F PF10791.9 GAX22891.1 - 0.066 13.7 1.1 0.11 13.0 0.4 1.7 1 1 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi LRR_4 PF12799.7 GAX22892.1 - 4e-26 90.7 43.4 0.00021 21.6 5.5 12.1 10 3 5 15 15 15 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX22892.1 - 4e-26 90.6 50.0 1.9e-06 27.5 0.1 10.2 3 2 13 16 16 16 11 Leucine rich repeat LRRNT_2 PF08263.12 GAX22892.1 - 1.8e-10 40.9 6.3 8.6e-05 22.8 0.1 3.7 3 0 0 3 3 3 2 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GAX22892.1 - 5.2e-09 35.4 40.4 2.1 9.2 0.7 16.1 16 2 1 17 17 17 2 Leucine Rich Repeat Ephrin_rec_like PF07699.13 GAX22892.1 - 0.00015 21.5 7.7 0.0016 18.2 1.8 2.4 2 0 0 2 2 2 2 Putative ephrin-receptor like LRR_9 PF14580.6 GAX22892.1 - 0.0012 18.4 0.4 0.23 11.0 0.1 3.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 GAX22892.1 - 0.0063 16.5 47.0 6.4 7.1 0.1 14.8 17 0 0 17 17 17 1 Leucine Rich repeat EF-hand_5 PF13202.6 GAX22892.1 - 0.14 11.7 0.4 1 9.0 0.0 2.5 2 0 0 2 2 2 0 EF hand TNFR_c6 PF00020.18 GAX22892.1 - 0.27 11.7 6.3 7.4 7.1 0.3 2.6 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region PseudoU_synth_2 PF00849.22 GAX22893.1 - 1.3e-24 87.1 0.0 2.1e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase zf-met PF12874.7 GAX22893.1 - 0.066 13.6 0.2 0.066 13.6 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4451 PF14616.6 GAX22893.1 - 0.097 12.9 0.0 0.3 11.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) zf-C2H2_jaz PF12171.8 GAX22893.1 - 0.44 10.9 0.1 0.44 10.9 0.1 2.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAX22893.1 - 3.9 8.1 7.7 1.2 9.7 0.2 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Atg14 PF10186.9 GAX22894.1 - 2.5e-09 36.7 11.0 1.2e-07 31.1 11.0 2.2 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sec8_exocyst PF04048.14 GAX22894.1 - 0.041 13.8 0.5 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain SlyX PF04102.12 GAX22894.1 - 0.74 10.5 3.8 2.6 8.7 0.2 2.9 2 1 1 3 3 3 0 SlyX Ribosomal_S17_N PF16205.5 GAX22895.1 - 0.055 13.9 0.0 0.087 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal EF-hand_1 PF00036.32 GAX22896.1 - 1.1e-07 30.9 1.3 2.4e-07 29.8 1.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX22896.1 - 1.9e-07 30.5 0.8 3.4e-07 29.7 0.8 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 GAX22896.1 - 1e-05 25.2 0.4 1.9e-05 24.4 0.4 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 GAX22896.1 - 2.3e-05 24.8 1.2 3.1e-05 24.3 1.2 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAX22896.1 - 3.2e-05 23.2 0.3 5.6e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 EF hand DUF4125 PF13526.6 GAX22896.1 - 0.45 10.1 2.3 10 5.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4125) Aminotran_5 PF00266.19 GAX22897.1 - 8.4e-12 44.7 0.0 2.7e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DUF3352 PF11832.8 GAX22897.1 - 0.19 10.3 0.0 0.31 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) JmjC PF02373.22 GAX22899.1 - 1.1e-16 61.3 0.0 2.6e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GAX22899.1 - 2.1e-14 53.9 0.0 8.2e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX22899.1 - 0.0063 16.0 0.0 0.024 14.1 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 GAX22899.1 - 0.044 13.4 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Cupin GATase_4 PF13230.6 GAX22900.1 - 1.7e-58 197.7 0.0 8.3e-51 172.5 0.0 2.0 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAX22900.1 - 0.00028 21.1 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Methyltransf_11 PF08241.12 GAX22901.1 - 3.9e-21 75.5 0.0 7.3e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX22901.1 - 9.5e-19 67.9 0.0 1.7e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX22901.1 - 2.6e-16 59.8 0.0 4.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAX22901.1 - 4.9e-15 55.6 0.0 6.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAX22901.1 - 3e-14 53.2 0.0 4.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22901.1 - 2.6e-12 47.3 0.0 5.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX22901.1 - 1.8e-09 37.3 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAX22901.1 - 9.7e-06 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 GAX22901.1 - 0.0094 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_20 PF12147.8 GAX22901.1 - 0.015 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 GAX22901.1 - 0.055 13.2 0.0 0.98 9.1 0.0 2.3 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 GAX22901.1 - 0.077 12.1 0.0 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 GAX22901.1 - 0.086 12.4 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 GAX22901.1 - 0.13 11.7 0.0 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase NAS PF03059.16 GAX22901.1 - 0.19 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Uds1 PF15456.6 GAX22902.1 - 0.045 13.9 0.8 0.08 13.1 0.8 1.6 1 1 0 1 1 1 0 Up-regulated During Septation LacI PF00356.21 GAX22903.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.0 2 1 0 2 2 2 0 Bacterial regulatory proteins, lacI family YchF-GTPase_C PF06071.13 GAX22904.1 - 1.6e-36 124.4 0.8 4.1e-36 123.0 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAX22904.1 - 1.9e-20 73.0 0.0 5.6e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX22904.1 - 1e-05 25.2 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF3390 PF11870.8 GAX22904.1 - 0.11 12.8 0.1 4.6 7.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3390) COPI_assoc PF08507.10 GAX22905.1 - 0.88 9.6 6.1 1.2 9.2 5.4 1.5 1 1 0 1 1 1 0 COPI associated protein Met_synt_B12 PF02965.17 GAX22907.1 - 1.4e-108 362.6 0.0 2.3e-108 361.8 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 GAX22907.1 - 2.3e-68 230.9 0.0 6.1e-68 229.5 0.0 1.8 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 GAX22907.1 - 4.9e-47 160.7 0.2 9.1e-47 159.8 0.2 1.5 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 GAX22907.1 - 4.2e-26 91.2 1.1 7e-26 90.5 0.1 2.0 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 GAX22907.1 - 8.1e-18 64.6 0.0 3.9e-16 59.2 0.1 2.8 2 0 0 2 2 2 1 B12 binding domain UQ_con PF00179.26 GAX22908.1 - 4.9e-33 113.7 0.0 6.4e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rep_4 PF05797.11 GAX22908.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) KH_1 PF00013.29 GAX22909.1 - 1.4e-27 95.3 0.0 1.5e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 GAX22909.1 - 6.9e-06 25.8 0.0 0.077 12.8 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 GAX22909.1 - 0.15 11.9 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 KH domain Solute_trans_a PF03619.16 GAX22910.1 - 2.4e-92 309.2 12.2 2.4e-92 309.2 12.2 1.6 2 0 0 2 2 2 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.16 GAX22911.1 - 1.9e-91 306.3 16.3 3.3e-91 305.5 16.3 1.4 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4407 PF14362.6 GAX22911.1 - 1.2 8.4 3.2 0.44 9.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cwf_Cwc_15 PF04889.12 GAX22911.1 - 3.4 7.3 16.5 0.2 11.3 3.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 GAX22912.1 - 0.049 13.8 4.4 0.13 12.5 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) EBV-NA3 PF05009.12 GAX22912.1 - 0.071 12.6 7.8 0.55 9.7 3.5 2.4 2 1 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FAM163 PF15069.6 GAX22912.1 - 0.12 12.8 4.4 0.12 12.9 3.3 1.5 1 1 0 1 1 1 0 FAM163 family DUF4778 PF16008.5 GAX22912.1 - 0.13 12.3 6.7 0.062 13.4 4.1 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4778) Dicty_REP PF05086.12 GAX22912.1 - 0.36 8.8 9.2 0.55 8.1 9.2 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAM176 PF14851.6 GAX22912.1 - 1.8 8.2 10.4 3.5 7.3 10.4 1.7 1 1 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GAX22912.1 - 4.9 6.4 7.9 7.9 5.7 7.9 1.2 1 0 0 1 1 1 0 NOA36 protein HbrB PF08539.11 GAX22912.1 - 6.2 6.8 8.1 0.25 11.3 0.9 2.1 1 1 1 2 2 2 0 HbrB-like Axin_b-cat_bind PF08833.10 GAX22912.1 - 7.6 6.7 7.9 13 6.0 0.7 3.1 3 0 0 3 3 3 0 Axin beta-catenin binding domain PBP1_TM PF14812.6 GAX22912.1 - 9.4 6.7 8.9 2.1 8.8 5.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MTS PF05175.14 GAX22913.1 - 2.8e-15 56.3 0.0 6.5e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 GAX22913.1 - 1.8e-08 34.1 0.0 2.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX22913.1 - 5.6e-06 27.0 0.0 1.7e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX22913.1 - 7.5e-05 22.4 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 GAX22913.1 - 7.9e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX22913.1 - 0.00043 20.2 0.0 0.0043 16.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 GAX22913.1 - 0.0006 19.2 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 GAX22913.1 - 0.001 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 GAX22913.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX22913.1 - 0.004 16.9 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 GAX22913.1 - 0.0054 16.3 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.16 GAX22913.1 - 0.023 13.9 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Ubie_methyltran PF01209.18 GAX22913.1 - 0.032 13.6 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GAX22913.1 - 0.11 13.1 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22913.1 - 0.16 12.7 0.1 0.43 11.3 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF3458_C PF17432.2 GAX22914.1 - 4.4e-99 331.9 2.0 8e-99 331.0 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 GAX22914.1 - 1.1e-54 185.3 0.7 1.9e-54 184.6 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain DUF3458 PF11940.8 GAX22914.1 - 2.2e-23 82.5 0.0 7.6e-23 80.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 GAX22914.1 - 1.1e-13 51.7 0.2 2.3e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain LcrR PF09621.10 GAX22914.1 - 0.042 13.3 0.6 4.7 6.7 0.0 2.7 2 1 0 2 2 2 0 Type III secretion system regulator (LcrR) Peptidase_M61 PF05299.12 GAX22914.1 - 0.088 13.2 0.2 0.39 11.1 0.2 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase CBM_X2 PF03442.14 GAX22914.1 - 0.27 11.4 2.6 0.52 10.5 0.4 2.6 3 0 0 3 3 3 0 Carbohydrate binding domain X2 RNA_pol_Rpc34 PF05158.12 GAX22915.1 - 2.6e-50 171.7 3.9 7.2e-44 150.5 0.5 2.2 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 GAX22915.1 - 0.0088 16.2 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DUF4527 PF15030.6 GAX22915.1 - 0.044 13.2 0.5 0.085 12.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) TFIIE_alpha PF02002.17 GAX22915.1 - 0.045 13.6 0.5 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit zf-TAZ PF02135.16 GAX22916.1 - 1.6e-06 28.4 19.2 7.9e-06 26.2 19.2 2.1 1 1 0 1 1 1 1 TAZ zinc finger DUF755 PF05501.11 GAX22916.1 - 7.5 6.9 11.3 0.55 10.5 5.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SET PF00856.28 GAX22917.1 - 1.6e-12 48.2 0.0 3.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 GAX22917.1 - 2.3e-10 41.2 0.1 1.6e-09 38.5 0.1 2.2 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Cu_amine_oxid PF01179.20 GAX22918.1 - 1.2e-152 508.6 0.0 1.7e-152 508.1 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAX22918.1 - 3.7e-11 43.3 0.2 2.4e-10 40.7 0.1 2.4 2 1 0 2 2 2 1 Copper amine oxidase, N3 domain RNA_pol_Rpb2_6 PF00562.28 GAX22919.1 - 9.6e-125 416.7 0.1 1.4e-124 416.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAX22919.1 - 4.5e-60 202.7 0.0 6.8e-60 202.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GAX22919.1 - 9.3e-48 162.4 0.0 1.6e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAX22919.1 - 6.7e-27 93.7 0.2 1.7e-26 92.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 GAX22919.1 - 2.3e-19 69.7 2.9 7e-19 68.2 2.9 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 GAX22919.1 - 5e-07 29.9 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 DUF4510 PF14971.6 GAX22921.1 - 0.00026 21.4 0.9 0.00032 21.1 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4510) JIP_LZII PF16471.5 GAX22921.1 - 0.00032 20.8 2.2 0.00032 20.8 2.2 2.5 2 1 0 2 2 2 1 JNK-interacting protein leucine zipper II Leu_zip PF15294.6 GAX22921.1 - 0.0015 18.1 8.5 0.0017 18.0 8.5 1.1 1 0 0 1 1 1 1 Leucine zipper HTH_21 PF13276.6 GAX22921.1 - 0.0032 17.6 0.1 0.011 15.8 0.0 2.1 2 1 1 3 3 2 1 HTH-like domain DivIVA PF05103.13 GAX22921.1 - 0.01 15.9 2.9 0.01 15.9 2.9 2.3 2 0 0 2 2 2 0 DivIVA protein NCA2 PF08637.10 GAX22921.1 - 0.027 13.6 4.5 0.029 13.5 4.5 1.0 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 DUF4618 PF15397.6 GAX22921.1 - 0.031 13.7 10.3 0.044 13.2 10.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) zf-C4H2 PF10146.9 GAX22921.1 - 0.033 14.5 9.7 0.035 14.4 9.7 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein FlaC_arch PF05377.11 GAX22921.1 - 0.071 13.5 8.0 0.29 11.5 2.1 2.7 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Herpes_UL6 PF01763.16 GAX22921.1 - 0.077 11.5 3.8 0.08 11.4 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4337 PF14235.6 GAX22921.1 - 0.16 12.0 6.2 0.19 11.8 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GED PF02212.18 GAX22921.1 - 0.3 11.3 9.2 0.11 12.7 4.0 2.0 2 0 0 2 2 2 0 Dynamin GTPase effector domain Paralemmin PF03285.15 GAX22921.1 - 0.31 10.6 8.4 0.4 10.2 8.4 1.3 1 1 0 1 1 1 0 Paralemmin Atg14 PF10186.9 GAX22921.1 - 0.4 9.7 9.2 0.45 9.6 9.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 GAX22921.1 - 0.41 11.1 18.3 0.44 11.0 9.7 2.9 1 1 1 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 GAX22921.1 - 0.51 9.2 12.4 0.65 8.8 12.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 GAX22921.1 - 0.53 9.5 9.3 0.96 8.7 9.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Cnn_1N PF07989.11 GAX22921.1 - 0.56 10.4 11.6 0.088 13.0 4.3 2.2 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 BLOC1_2 PF10046.9 GAX22921.1 - 0.88 9.9 12.5 0.32 11.3 5.7 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.6 GAX22921.1 - 0.92 9.6 9.2 2.3 8.3 9.2 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 NRBF2 PF08961.10 GAX22921.1 - 1.1 8.9 9.0 0.63 9.6 6.5 1.7 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator TMF_TATA_bd PF12325.8 GAX22921.1 - 2.5 8.4 15.9 5.3 7.3 15.9 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PikAIV_N PF18605.1 GAX22921.1 - 2.6 7.7 12.3 0.18 11.4 1.2 3.5 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain UPF0242 PF06785.11 GAX22921.1 - 3.1 7.8 12.9 9.9 6.2 12.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 GAX22921.1 - 6.2 6.7 14.9 0.15 11.9 3.3 2.9 1 1 1 2 2 2 0 Septum formation initiator KH_1 PF00013.29 GAX22922.1 - 4.8e-44 148.0 14.1 2.8e-15 55.9 0.3 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAX22922.1 - 2.3e-13 49.8 4.2 3.4e-05 23.6 0.1 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAX22922.1 - 2.3e-10 40.1 2.9 0.00023 20.9 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAX22922.1 - 0.0072 16.4 3.8 0.71 10.0 0.1 3.5 3 0 0 3 3 3 1 NusA-like KH domain SLS PF14611.6 GAX22922.1 - 0.017 15.0 0.4 0.35 10.7 0.0 2.9 2 2 2 4 4 4 0 Mitochondrial inner-membrane-bound regulator Remorin_N PF03766.13 GAX22922.1 - 0.046 13.8 0.5 0.046 13.8 0.5 2.5 3 0 0 3 3 3 0 Remorin, N-terminal region Peptidase_S10 PF00450.22 GAX22923.1 - 2e-94 317.4 0.0 3e-94 316.8 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase RSN1_7TM PF02714.15 GAX22924.1 - 2.8e-49 167.9 18.8 4.6e-49 167.2 18.8 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAX22924.1 - 9.8e-26 91.0 4.4 3.4e-17 63.2 0.8 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAX22924.1 - 2.2e-10 40.5 0.2 2.2e-10 40.5 0.2 3.0 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport UNC-93 PF05978.16 GAX22925.1 - 1.7e-05 24.6 7.4 1.7e-05 24.6 7.4 2.8 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 FAD_binding_1 PF00667.20 GAX22926.1 - 3.2e-28 98.8 0.0 5.9e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX22926.1 - 1.2e-27 96.9 0.0 2.6e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAX22926.1 - 4.9e-13 49.7 0.1 2e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain PIN_10 PF18478.1 GAX22926.1 - 0.11 12.7 0.0 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 PIN like domain rRNA_processing PF08524.11 GAX22927.1 - 2.9e-12 46.9 26.4 4.3e-12 46.3 26.3 1.3 1 1 0 1 1 1 1 rRNA processing Cdc6_C PF09079.11 GAX22927.1 - 0.06 13.3 1.2 1 9.4 0.1 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain CDC45 PF02724.14 GAX22927.1 - 3.7 5.7 14.2 4.5 5.5 14.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Homeobox_KN PF05920.11 GAX22928.1 - 5e-15 55.1 0.5 1.3e-14 53.7 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAX22928.1 - 1.1e-05 25.2 0.4 3.8e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 Homeodomain zf-C3HC4_2 PF13923.6 GAX22928.1 - 2.6e-05 23.9 7.6 4.8e-05 23.1 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX22928.1 - 0.00015 21.6 5.0 0.00026 20.8 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX22928.1 - 0.00025 21.3 5.9 0.00047 20.4 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX22928.1 - 0.0062 16.3 4.7 0.012 15.3 4.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAX22928.1 - 0.0068 16.2 4.6 0.01 15.6 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX22928.1 - 0.019 15.0 8.6 0.038 14.0 8.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX22928.1 - 0.02 14.7 5.5 0.037 13.9 5.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAX22928.1 - 0.039 13.9 4.1 0.082 12.9 4.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 GAX22928.1 - 0.039 14.2 4.7 0.095 13.0 4.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAX22928.1 - 1.2 9.3 4.5 2.6 8.2 4.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ras PF00071.22 GAX22929.1 - 9.7e-49 165.1 0.0 1.2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX22929.1 - 5.7e-30 104.0 0.0 1.5e-29 102.7 0.0 1.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX22929.1 - 1e-09 38.1 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX22929.1 - 9.5e-05 22.5 0.0 0.00026 21.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 GAX22929.1 - 0.00036 20.9 0.1 0.0013 19.1 0.1 1.9 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 GAX22929.1 - 0.0033 16.8 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ArgoMid PF16487.5 GAX22929.1 - 0.019 15.2 0.1 0.035 14.4 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute Septin PF00735.18 GAX22929.1 - 0.042 13.1 0.2 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 Septin SRPRB PF09439.10 GAX22929.1 - 0.05 13.0 0.0 0.081 12.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAX22929.1 - 0.057 13.1 0.1 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAX22929.1 - 0.059 13.3 0.1 1 9.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAX22929.1 - 0.072 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 GAX22929.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 GAX22929.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 GAX22929.1 - 0.088 12.0 1.5 2.1 7.4 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit TsaE PF02367.17 GAX22929.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAX22929.1 - 0.14 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAX22929.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 NTPase HEAT PF02985.22 GAX22930.1 - 2.9e-18 64.4 34.7 0.017 15.3 0.4 10.9 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 GAX22930.1 - 9.9e-11 41.9 22.1 0.016 15.5 0.1 7.5 5 3 2 7 7 7 5 HEAT repeats PDZ PF00595.24 GAX22930.1 - 2.3e-08 34.3 0.2 9.4e-08 32.3 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAX22930.1 - 4.2e-07 29.7 0.1 2.1e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Cnd1 PF12717.7 GAX22930.1 - 6.5e-06 26.3 8.4 0.39 10.7 0.1 5.6 5 2 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 PDZ_2 PF13180.6 GAX22930.1 - 1.7e-05 25.1 0.1 4.7e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Adaptin_N PF01602.20 GAX22930.1 - 6.5e-05 21.7 1.6 0.33 9.5 0.0 3.2 2 2 1 3 3 3 2 Adaptin N terminal region Arm PF00514.23 GAX22930.1 - 0.0017 18.3 5.9 0.48 10.5 0.2 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAX22930.1 - 0.023 15.2 21.0 3.2 8.4 0.1 6.9 7 1 1 8 8 7 0 HEAT-like repeat CLASP_N PF12348.8 GAX22930.1 - 0.029 13.9 1.1 9.4 5.7 0.0 4.4 5 0 0 5 5 5 0 CLASP N terminal TFCD_C PF12612.8 GAX22930.1 - 0.033 14.0 0.6 6 6.6 0.0 3.3 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal TraV PF09676.10 GAX22930.1 - 4.1 8.4 8.7 20 6.1 4.0 3.0 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) zf-HC5HC2H PF13771.6 GAX22931.1 - 0.015 15.5 2.1 0.047 13.9 2.1 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAX22931.1 - 0.045 13.9 1.5 0.12 12.6 1.5 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain GAS PF13851.6 GAX22931.1 - 2.8 7.2 57.1 1.3 8.3 16.5 3.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding HOOK PF05622.12 GAX22932.1 - 4.2e-13 48.4 58.7 2.5e-11 42.5 59.1 6.3 2 1 4 6 6 6 3 HOOK protein DUF3410 PF11890.8 GAX22932.1 - 0.18 11.6 0.1 0.18 11.6 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3410) DUF2358 PF10184.9 GAX22933.1 - 3.8e-06 27.1 0.1 1.2e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) 3Beta_HSD PF01073.19 GAX22934.1 - 4e-34 117.9 0.0 5e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAX22934.1 - 3.6e-25 88.8 0.0 5.1e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAX22934.1 - 8.3e-14 51.4 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 GAX22934.1 - 1.9e-11 43.6 0.0 4.2e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GAX22934.1 - 4.2e-11 42.8 0.0 9.1e-11 41.7 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX22934.1 - 5.2e-10 38.9 0.0 7.5e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAX22934.1 - 5.6e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAX22934.1 - 0.00026 20.9 0.0 0.0005 20.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 GAX22934.1 - 0.0023 17.4 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DprA_WH PF17782.1 GAX22935.1 - 0.013 15.6 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 DprA winged helix domain DUF3382 PF11862.8 GAX22935.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) ERO1 PF04137.15 GAX22936.1 - 3.7e-88 296.1 1.2 5.1e-88 295.6 1.2 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) FAD_binding_2 PF00890.24 GAX22936.1 - 3.3e-83 280.1 0.9 4.5e-83 279.6 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 GAX22936.1 - 1.4e-18 66.7 0.0 3.6e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 GAX22936.1 - 9.4e-10 38.6 3.1 2.6e-08 33.8 3.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX22936.1 - 2.6e-05 23.6 0.3 8.9e-05 21.9 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX22936.1 - 3.8e-05 23.8 0.6 0.00018 21.7 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAX22936.1 - 0.0005 19.5 1.8 0.001 18.5 1.8 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX22936.1 - 0.0031 16.3 0.6 0.087 11.5 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAX22936.1 - 0.007 15.7 1.7 0.47 9.7 0.7 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAX22936.1 - 0.014 14.8 0.3 0.27 10.4 0.1 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GAX22936.1 - 0.014 15.9 1.0 0.66 10.6 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX22936.1 - 0.016 14.5 1.3 0.033 13.4 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 GAX22936.1 - 0.061 12.6 0.1 0.061 12.6 0.1 3.0 4 1 0 4 4 4 0 Thi4 family NAD_binding_9 PF13454.6 GAX22936.1 - 0.071 13.1 0.9 0.6 10.1 0.4 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAX22936.1 - 0.23 10.5 0.5 0.39 9.7 0.5 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 GAX22936.1 - 0.7 8.9 2.9 1.4 7.9 0.3 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A OsmC PF02566.19 GAX22937.1 - 8.8e-09 35.8 0.1 2.3e-08 34.4 0.1 1.7 1 1 0 1 1 1 1 OsmC-like protein SIP1 PF04938.12 GAX22938.1 - 3.5e-31 108.6 0.1 4.3e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GCP_N_terminal PF17681.1 GAX22938.1 - 0.049 13.3 0.3 0.12 11.9 0.2 1.6 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal CAP_N PF01213.19 GAX22938.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PAP2 PF01569.21 GAX22939.1 - 0.006 16.4 0.5 0.078 12.7 0.0 2.2 1 1 1 2 2 2 1 PAP2 superfamily Scs3p PF10261.9 GAX22939.1 - 0.012 15.1 0.1 0.043 13.3 0.0 1.7 2 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM ABC1 PF03109.16 GAX22940.1 - 2.3e-31 108.4 0.0 4.2e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family SKA1 PF07160.12 GAX22940.1 - 0.16 11.8 1.2 0.33 10.8 1.2 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CBFB_NFYA PF02045.15 GAX22941.1 - 3.3e-23 82.1 8.9 4.7e-23 81.6 8.9 1.2 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Patatin PF01734.22 GAX22943.1 - 3.6e-13 50.2 0.3 2.9e-10 40.7 0.3 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase LPMO_10 PF03067.15 GAX22944.1 - 3.1e-22 80.2 1.1 4.1e-22 79.8 1.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PsbP PF01789.16 GAX22947.1 - 4.5e-15 56.1 0.0 4.3e-14 52.9 0.0 2.2 1 1 0 1 1 1 1 PsbP Pyrid_oxidase_2 PF13883.6 GAX22949.1 - 8.4e-30 104.0 0.1 6.9e-14 52.2 0.1 2.1 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase DUF285 PF03382.14 GAX22951.1 - 7.5e-61 203.2 30.1 1e-32 112.5 10.9 2.6 1 1 2 3 3 3 2 Mycoplasma protein of unknown function, DUF285 Phage_tail_L PF05100.12 GAX22951.1 - 0.022 14.1 0.2 0.033 13.5 0.2 1.3 1 0 0 1 1 1 0 Phage minor tail protein L DUF5030 PF16433.5 GAX22951.1 - 0.07 12.5 0.1 3.9 6.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5030) DUF285 PF03382.14 GAX22952.1 - 2.3e-67 224.3 20.8 7.2e-35 119.4 3.5 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 U5_2-snRNA_bdg PF10597.9 GAX22952.1 - 0.0041 17.2 1.2 0.038 14.1 0.3 2.6 1 1 3 4 4 4 1 U5-snRNA binding site 2 of PrP8 Fasciclin PF02469.22 GAX22953.1 - 9.5e-08 32.3 0.0 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain MPC PF03650.13 GAX22954.1 - 0.062 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers HemolysinCabind PF00353.19 GAX22955.1 - 2.3e-11 43.5 78.4 1.6e-06 27.9 12.4 23.5 22 4 3 25 25 25 13 RTX calcium-binding nonapeptide repeat (4 copies) Fer2 PF00111.27 GAX22957.1 - 1.3e-10 41.1 0.6 1.7e-10 40.7 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ABC_tran PF00005.27 GAX22958.1 - 1.1e-38 132.8 2.4 8.7e-22 78.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX22958.1 - 6.8e-18 64.5 4.8 1.6e-17 63.3 4.8 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAX22958.1 - 6.2e-17 61.8 1.7 3.3e-08 33.2 0.3 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX22958.1 - 2.9e-15 56.8 1.0 0.00028 20.8 0.0 4.4 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX22958.1 - 1.5e-09 37.4 0.1 0.00072 19.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 GAX22958.1 - 5.1e-08 33.2 0.8 0.00014 22.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 GAX22958.1 - 2.1e-07 31.7 4.3 0.015 15.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 GAX22958.1 - 2e-06 27.8 0.2 0.0038 17.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAX22958.1 - 6.8e-05 22.9 0.0 0.0081 16.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_27 PF13514.6 GAX22958.1 - 0.00016 21.4 0.9 0.44 10.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 GAX22958.1 - 0.00026 20.8 0.0 0.34 10.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 GAX22958.1 - 0.00026 21.4 3.1 0.58 10.5 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAX22958.1 - 0.00038 20.8 4.1 0.17 12.2 0.3 3.4 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GAX22958.1 - 0.00059 19.9 0.1 0.025 14.6 0.0 2.6 2 1 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 GAX22958.1 - 0.0018 18.0 0.2 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 GAX22958.1 - 0.0021 17.1 0.1 0.27 10.1 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain G-alpha PF00503.20 GAX22958.1 - 0.003 16.8 0.1 0.64 9.1 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_30 PF13604.6 GAX22958.1 - 0.0036 17.0 3.9 1 9.0 0.1 2.9 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 GAX22958.1 - 0.0037 16.6 4.6 0.21 10.9 0.0 3.4 4 0 0 4 4 4 1 Zeta toxin NACHT PF05729.12 GAX22958.1 - 0.0043 17.0 2.0 0.85 9.5 0.1 2.7 3 0 0 3 3 3 1 NACHT domain MutS_V PF00488.21 GAX22958.1 - 0.0051 16.9 0.5 2.9 7.9 0.0 3.1 3 0 0 3 3 3 1 MutS domain V AAA_18 PF13238.6 GAX22958.1 - 0.0092 16.5 0.1 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 GAX22958.1 - 0.01 15.3 0.5 1.1 8.7 0.1 2.8 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.19 GAX22958.1 - 0.022 14.3 1.4 2 8.0 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAX22958.1 - 0.023 15.1 0.1 12 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 GAX22958.1 - 0.03 14.1 0.3 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 GAX22958.1 - 0.033 13.2 0.5 2.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 GAX22958.1 - 0.041 13.5 0.2 2.1 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 GAX22958.1 - 0.042 14.1 0.5 1.2 9.4 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 GAX22958.1 - 0.053 13.0 0.3 5.9 6.4 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DAP3 PF10236.9 GAX22958.1 - 0.064 12.4 1.8 1.6 7.8 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 MukB PF04310.12 GAX22958.1 - 0.075 12.8 0.7 3.4 7.4 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_17 PF13207.6 GAX22958.1 - 0.11 13.0 4.8 1.8 9.0 0.2 3.2 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 GAX22958.1 - 0.11 13.0 0.2 6 7.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 GAX22958.1 - 0.13 12.3 0.1 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AIG1 PF04548.16 GAX22958.1 - 0.15 11.4 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_13 PF13166.6 GAX22958.1 - 0.16 10.6 1.6 32 3.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 GAX22958.1 - 0.19 11.6 0.1 0.5 10.3 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 GAX22958.1 - 0.22 10.9 5.4 3.3 7.0 0.1 3.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 GAX22958.1 - 0.26 11.2 1.6 17 5.3 0.1 2.5 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 GAX22958.1 - 0.79 9.6 3.0 1.9 8.3 0.1 2.7 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 GAX22958.1 - 1.5 9.0 4.8 24 5.1 0.7 3.0 3 1 0 3 3 3 0 AAA domain DZR PF12773.7 GAX22959.1 - 0.0079 16.2 4.0 0.011 15.8 4.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon Zn_Tnp_IS1 PF03811.13 GAX22959.1 - 0.013 15.2 0.7 0.013 15.2 0.7 2.4 3 0 0 3 3 3 0 InsA N-terminal domain zinc_ribbon_4 PF13717.6 GAX22959.1 - 0.019 14.8 2.7 0.019 14.8 2.7 2.1 2 1 0 2 2 2 0 zinc-ribbon domain zf-LSD1 PF06943.12 GAX22959.1 - 0.023 14.6 0.3 0.044 13.6 0.3 1.5 1 0 0 1 1 1 0 LSD1 zinc finger HypA PF01155.19 GAX22959.1 - 0.04 13.9 0.9 0.048 13.7 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C26 PF07722.13 GAX22960.1 - 2.1e-10 40.7 0.0 9.1e-09 35.4 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 GAX22960.1 - 9.7e-09 35.3 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 GAX22960.1 - 0.0005 20.0 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family HSF_DNA-bind PF00447.17 GAX22961.1 - 6.3e-12 45.9 0.0 9.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Rotamase PF00639.21 GAX22962.1 - 4.1e-16 59.7 0.0 6.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX22962.1 - 2.1e-12 47.6 0.0 3.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAX22962.1 - 0.00018 22.4 0.0 0.00029 21.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Asp_protease_2 PF13650.6 GAX22963.1 - 0.00031 21.3 0.0 0.13 12.9 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAX22963.1 - 0.053 14.1 0.0 2.5 8.7 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease ArsC PF03960.15 GAX22963.1 - 0.07 13.2 0.0 0.54 10.3 0.0 2.2 2 1 0 2 2 2 0 ArsC family Sigma70_r2 PF04542.14 GAX22964.1 - 2.8e-05 23.8 0.4 0.00037 20.2 0.1 2.6 2 1 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GAX22964.1 - 9e-05 21.9 0.5 0.0015 18.0 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 GAX22964.1 - 0.016 15.3 5.2 0.12 12.5 0.1 3.6 4 0 0 4 4 4 0 Sigma-70 region 3 Asn_synthase PF00733.21 GAX22964.1 - 0.034 13.8 3.8 0.053 13.2 3.8 1.4 1 1 0 1 1 1 0 Asparagine synthase CtsR PF05848.11 GAX22964.1 - 0.056 13.4 0.2 5.9 6.9 0.0 3.1 3 0 0 3 3 3 0 CtsR N-terminal HTH domain Ribosomal_L22 PF00237.19 GAX22965.1 - 1.4e-33 115.2 0.2 1.9e-33 114.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Amidohydro_3 PF07969.11 GAX22965.1 - 0.0025 17.4 0.1 0.0026 17.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family ubiquitin PF00240.23 GAX22966.1 - 5.5e-08 32.4 0.1 8.9e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX22966.1 - 4.2e-06 26.5 0.2 2.4e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 GAX22966.1 - 0.0099 16.6 0.4 0.029 15.1 0.4 1.9 1 1 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF4006 PF13179.6 GAX22966.1 - 0.18 11.8 0.5 0.46 10.4 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF4006) LRR_8 PF13855.6 GAX22969.1 - 8.8e-10 38.2 8.1 1.5e-06 27.8 5.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX22969.1 - 6.2e-07 29.6 8.0 0.00049 20.4 2.4 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX22969.1 - 8.5e-06 25.6 2.8 7.7 7.5 0.1 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX22969.1 - 0.042 13.9 3.6 5 7.4 0.5 3.0 2 0 0 2 2 2 0 Leucine Rich repeat Beta_helix PF13229.6 GAX22970.1 - 5e-10 39.4 1.5 9e-10 38.6 1.5 1.3 1 0 0 1 1 1 1 Right handed beta helix region HORMA PF02301.18 GAX22971.1 - 0.019 14.6 0.0 0.1 12.2 0.0 1.9 1 1 0 1 1 1 0 HORMA domain F-actin_cap_A PF01267.17 GAX22972.1 - 5.1e-21 75.3 1.9 2.4e-19 69.8 1.8 2.2 1 1 0 1 1 1 1 F-actin capping protein alpha subunit Arm PF00514.23 GAX22974.1 - 2.7e-97 316.2 15.8 2.3e-12 46.5 0.2 8.6 9 0 0 9 9 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAX22974.1 - 1.5e-34 118.0 3.0 3.6e-11 43.3 0.0 7.0 5 2 2 7 7 7 6 HEAT-like repeat HEAT_2 PF13646.6 GAX22974.1 - 5.9e-25 87.5 0.1 4.4e-08 33.4 0.0 5.8 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 GAX22974.1 - 4.1e-23 79.5 4.0 3.1e-05 23.9 0.0 8.1 8 0 0 8 8 8 4 HEAT repeat IBB PF01749.20 GAX22974.1 - 2.5e-19 69.5 0.7 1.2e-18 67.3 0.8 2.2 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 GAX22974.1 - 1.9e-18 65.8 0.8 3.1e-17 61.9 2.8 2.0 2 0 0 2 2 2 1 Atypical Arm repeat Arm_2 PF04826.13 GAX22974.1 - 4.8e-11 42.6 0.1 0.00076 19.0 0.0 3.8 1 1 3 5 5 5 2 Armadillo-like Cnd1 PF12717.7 GAX22974.1 - 2.5e-08 34.1 0.0 0.028 14.5 0.0 3.8 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAX22974.1 - 8.6e-08 31.2 0.0 0.0059 15.2 0.0 3.1 1 1 2 3 3 3 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 GAX22974.1 - 3.6e-07 30.3 0.0 3 8.0 0.0 4.3 3 1 2 5 5 5 4 V-ATPase subunit H RICTOR_V PF14668.6 GAX22974.1 - 3.7e-05 23.9 1.7 2.5 8.4 0.0 5.1 4 2 3 7 7 6 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 GAX22974.1 - 0.00015 22.1 0.1 1 10.2 0.0 5.5 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 GAX22974.1 - 0.00017 21.5 0.1 1.6 8.8 0.2 3.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain NopRA1 PF16201.5 GAX22974.1 - 0.00058 19.5 0.0 47 3.5 0.0 5.4 4 2 2 6 6 6 0 Nucleolar pre-ribosomal-associated protein 1 Mo25 PF08569.11 GAX22974.1 - 0.00067 19.1 0.0 0.029 13.7 0.0 2.4 1 1 1 2 2 2 1 Mo25-like Vps35 PF03635.17 GAX22974.1 - 0.016 13.7 0.0 0.026 13.1 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Nipped-B_C PF12830.7 GAX22974.1 - 0.19 11.7 0.0 1.4 8.8 0.0 2.3 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus Choline_transpo PF04515.12 GAX22975.1 - 2.2e-15 56.7 7.8 1.8e-14 53.7 7.8 2.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter Orn_Arg_deC_N PF02784.16 GAX22976.1 - 2.4e-65 220.4 0.0 7.1e-65 218.8 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAX22976.1 - 7.1e-13 48.6 0.0 2.9e-11 43.5 0.0 2.5 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain FBPase_2 PF06874.11 GAX22976.1 - 0.071 11.4 0.1 4.1 5.6 0.1 2.1 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase Filament PF00038.21 GAX22977.1 - 0.00037 20.2 35.7 0.00037 20.2 35.7 9.2 1 1 8 9 9 9 3 Intermediate filament protein Golgin_A5 PF09787.9 GAX22977.1 - 0.0014 18.2 22.9 0.0014 18.2 22.9 9.0 1 1 9 10 10 10 2 Golgin subfamily A member 5 KASH_CCD PF14662.6 GAX22977.1 - 0.0071 16.2 16.5 0.0071 16.2 16.5 9.6 1 1 9 10 10 10 3 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.5 GAX22977.1 - 0.0087 16.2 8.4 0.0087 16.2 8.4 15.9 15 5 4 19 19 19 1 JNK-interacting protein leucine zipper II ATG16 PF08614.11 GAX22977.1 - 0.01 16.1 16.2 0.01 16.1 16.2 11.4 2 2 7 11 11 11 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAX22977.1 - 0.1 11.5 211.4 0.049 12.5 25.0 10.0 1 1 9 11 11 11 0 Spc7 kinetochore protein Antimicrobial19 PF08225.11 GAX22977.1 - 1.5 8.5 3.5 5.1 6.8 0.1 2.7 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Asp_protease_2 PF13650.6 GAX22978.1 - 2.3e-19 69.8 0.4 1.8e-11 44.5 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAX22978.1 - 1e-14 54.9 0.0 2.8e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GAX22978.1 - 0.013 15.3 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease CitT PF12431.8 GAX22978.1 - 0.013 15.8 1.4 5.4 7.5 0.2 2.6 2 0 0 2 2 2 0 Transcriptional regulator DUF1758 PF05585.12 GAX22978.1 - 0.024 14.4 0.1 0.064 13.0 0.0 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF1758) SAP PF02037.27 GAX22978.1 - 0.073 12.9 0.9 0.25 11.1 0.9 1.8 1 1 0 1 1 1 0 SAP domain RVP PF00077.20 GAX22978.1 - 0.1 12.9 0.0 8.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease FlhE PF06366.13 GAX22978.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FlhE Ribosomal_L29 PF00831.23 GAX22978.1 - 0.48 10.4 2.3 0.43 10.6 0.4 1.8 2 0 0 2 2 2 0 Ribosomal L29 protein SLX9 PF15341.6 GAX22979.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 VPS11_C PF12451.8 GAX22979.1 - 0.2 11.9 0.7 0.35 11.1 0.7 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal ResIII PF04851.15 GAX22981.1 - 4.4e-22 78.9 0.0 1.2e-21 77.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX22981.1 - 2.5e-19 69.6 0.6 7e-19 68.2 0.6 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX22981.1 - 7.6e-16 58.4 0.0 1.7e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 GAX22981.1 - 3.3e-07 30.1 3.3 3.3e-07 30.1 3.3 3.3 4 0 0 4 4 4 1 PHD-finger PHD_2 PF13831.6 GAX22981.1 - 6.2e-06 25.7 1.4 6.2e-06 25.7 1.4 3.3 3 0 0 3 3 3 1 PHD-finger Val_tRNA-synt_C PF10458.9 GAX22981.1 - 0.088 13.1 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm DNA_mis_repair PF01119.19 GAX22982.1 - 5.2e-21 74.5 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 GAX22982.1 - 1.3e-19 70.5 0.0 5.3e-18 65.2 0.0 2.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 GAX22982.1 - 6.6e-05 23.4 0.0 0.00023 21.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX22982.1 - 7.3e-05 22.6 0.0 0.00022 21.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LRR_8 PF13855.6 GAX22984.1 - 3.3e-19 68.4 3.8 4.5e-08 32.7 0.1 4.4 2 1 2 4 4 4 3 Leucine rich repeat Pkinase PF00069.25 GAX22984.1 - 1.7e-11 44.0 0.0 2.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 GAX22984.1 - 5.4e-10 39.4 10.5 0.00018 21.8 0.4 4.9 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAX22984.1 - 4.7e-05 22.9 1.2 0.036 13.6 0.4 2.7 1 1 1 2 2 2 2 Leucine-rich repeat Pkinase_Tyr PF07714.17 GAX22984.1 - 5.4e-05 22.6 0.0 0.00015 21.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX22984.1 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX22984.1 - 0.0029 17.6 0.1 0.011 15.7 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family LRR_5 PF13306.6 GAX22984.1 - 0.035 14.1 0.2 0.074 13.0 0.2 1.5 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) RIO1 PF01163.22 GAX22984.1 - 0.18 11.4 0.0 0.75 9.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family LRR_1 PF00560.33 GAX22984.1 - 0.83 10.4 8.3 31 5.6 0.0 6.1 6 2 0 6 6 6 0 Leucine Rich Repeat Methyltransf_16 PF10294.9 GAX22985.1 - 6.1e-25 87.9 0.0 1.4e-22 80.3 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAX22985.1 - 0.00046 20.1 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAX22985.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 GAX22985.1 - 0.11 13.2 0.1 0.51 11.1 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX22985.1 - 0.12 13.1 0.0 0.76 10.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Cyclin_N PF00134.23 GAX22986.1 - 4e-07 29.8 2.2 0.00042 20.1 0.1 3.1 3 0 0 3 3 3 2 Cyclin, N-terminal domain 3HCDH_RFF PF18321.1 GAX22986.1 - 0.14 12.6 1.7 51 4.4 0.0 3.4 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Alk_phosphatase PF00245.20 GAX22987.1 - 1.7e-31 109.6 5.5 6.3e-16 58.3 0.0 3.2 3 0 0 3 3 3 3 Alkaline phosphatase GDPD PF03009.17 GAX22987.1 - 1.9e-18 67.1 0.0 4.7e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Metalloenzyme PF01676.18 GAX22987.1 - 0.00071 19.0 0.5 0.0035 16.7 0.0 2.1 2 1 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 GAX22987.1 - 0.0023 17.4 0.2 0.081 12.3 0.3 2.3 2 0 0 2 2 2 1 Sulfatase zf-MYND PF01753.18 GAX22988.1 - 1.3e-09 37.9 15.0 1.3e-09 37.9 15.0 2.7 2 1 0 2 2 2 1 MYND finger zf-C3HC4_3 PF13920.6 GAX22988.1 - 2.2e-08 33.8 3.5 2.2e-08 33.8 3.5 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX22988.1 - 6.5e-07 29.6 5.5 6.5e-07 29.6 5.5 2.5 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX22988.1 - 1.5e-06 28.1 4.5 1.6e-06 28.1 2.5 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX22988.1 - 2.5e-06 27.3 5.4 2.5e-06 27.3 5.4 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 GAX22988.1 - 2.5e-05 24.0 5.1 0.28 11.4 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 GAX22988.1 - 2.7e-05 24.0 5.8 2.7e-05 24.0 5.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain TPR_12 PF13424.6 GAX22988.1 - 0.00024 21.3 5.2 0.22 11.8 1.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 GAX22988.1 - 0.00038 20.2 9.0 0.00038 20.2 9.0 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 GAX22988.1 - 0.001 19.7 4.4 11 7.2 0.4 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX22988.1 - 0.0013 19.2 4.7 0.19 12.3 1.5 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GAX22988.1 - 0.0049 16.7 2.7 0.021 14.7 2.7 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TPR_6 PF13174.6 GAX22988.1 - 0.0068 17.0 8.6 0.15 12.7 0.4 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat FAM76 PF16046.5 GAX22988.1 - 0.017 14.5 0.8 0.017 14.5 0.8 2.2 2 0 0 2 2 2 0 FAM76 protein zf-Nse PF11789.8 GAX22988.1 - 0.056 13.3 1.3 0.13 12.1 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 GAX22988.1 - 0.066 13.0 6.5 0.16 11.8 6.5 1.7 1 0 0 1 1 1 0 RING-like zinc finger TPR_7 PF13176.6 GAX22988.1 - 0.068 13.2 2.1 44 4.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat YfiO PF13525.6 GAX22988.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_16 PF13432.6 GAX22988.1 - 0.076 13.7 1.5 4.1 8.1 0.0 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX22988.1 - 0.15 12.0 8.7 0.46 10.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX22988.1 - 0.18 11.6 8.2 10 6.1 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-MIZ PF02891.20 GAX22988.1 - 1.8 8.4 10.2 0.046 13.5 3.2 2.0 2 0 0 2 2 1 0 MIZ/SP-RING zinc finger TPR_14 PF13428.6 GAX22989.1 - 3.4e-13 49.2 18.4 0.0015 19.2 1.7 9.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX22989.1 - 1.8e-10 40.1 17.5 0.0014 18.5 0.1 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX22989.1 - 1.8e-08 33.8 2.3 0.12 12.4 0.0 5.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX22989.1 - 2.9e-07 30.0 7.3 0.00086 18.9 0.0 6.4 7 0 0 7 7 7 1 TPR repeat TPR_12 PF13424.6 GAX22989.1 - 8.6e-07 29.2 17.9 0.00068 19.9 0.0 7.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX22989.1 - 2.1e-06 27.5 6.2 2.1 8.8 0.2 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX22989.1 - 3.1e-06 27.2 3.7 2.1 8.9 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX22989.1 - 8.5e-05 22.2 13.3 0.16 11.9 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX22989.1 - 0.0006 20.4 26.3 1.8 9.3 2.5 6.7 6 1 0 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX22989.1 - 0.0013 19.2 24.1 0.036 14.6 1.8 7.5 7 1 2 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX22989.1 - 0.0065 17.0 12.1 20 6.1 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX22989.1 - 0.08 13.1 2.7 24 5.2 0.5 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1202 PF06717.11 GAX22990.1 - 0.0068 15.9 0.1 0.008 15.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1202) SKA2 PF16740.5 GAX22990.1 - 0.037 13.8 2.9 0.09 12.6 2.9 1.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 GAX22990.1 - 0.13 12.8 5.6 1.2 9.7 5.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 GAX22990.1 - 0.52 10.4 6.0 7.2 6.8 2.1 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 RNA_pol_A_CTD PF03118.15 GAX22991.1 - 0.0021 17.8 0.4 0.38 10.5 0.4 2.5 2 0 0 2 2 2 2 Bacterial RNA polymerase, alpha chain C terminal domain Urocanase PF01175.18 GAX22993.1 - 0.093 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain DUF4440 PF14534.6 GAX22994.1 - 5.9e-06 26.6 0.0 0.23 11.9 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4440) SnoaL PF07366.12 GAX22994.1 - 0.001 18.9 0.1 0.0042 16.9 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAX22994.1 - 0.04 14.5 0.0 0.23 12.1 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain Hamartin PF04388.12 GAX22994.1 - 1.2 7.7 34.4 1.6 7.3 34.4 1.1 1 0 0 1 1 1 0 Hamartin protein Borrelia_P83 PF05262.11 GAX22994.1 - 8.2 4.8 43.1 14 4.1 43.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_trans_2_3 PF13632.6 GAX22995.1 - 7.5e-24 84.7 0.6 7.5e-24 84.7 0.6 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX22995.1 - 1.9e-19 70.5 0.0 3.6e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX22995.1 - 1.1e-13 51.3 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX22995.1 - 5.5e-09 35.7 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 SPC25 PF06703.11 GAX22995.1 - 0.027 14.3 0.0 0.083 12.7 0.0 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Glyco_tranf_2_2 PF10111.9 GAX22995.1 - 0.14 11.6 0.0 0.41 10.1 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Acylphosphatase PF00708.18 GAX22996.1 - 1.4e-10 41.4 0.2 1.7e-10 41.2 0.2 1.1 1 0 0 1 1 1 1 Acylphosphatase Ribosomal_L44 PF00935.19 GAX22997.1 - 4.5e-32 110.4 12.6 6e-32 110.0 12.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Sar8_2 PF03058.14 GAX22997.1 - 0.79 10.3 5.7 1.5 9.4 5.7 1.6 1 1 0 1 1 1 0 Sar8.2 family HLH PF00010.26 GAX22998.1 - 1.3e-07 31.5 1.3 2.3e-07 30.7 1.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 GAX22998.1 - 0.0081 16.4 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 2 1 PAS domain DUF745 PF05335.13 GAX22998.1 - 8.6 6.0 9.9 0.8 9.4 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) HLH PF00010.26 GAX22999.1 - 1.4e-05 24.9 2.5 4.6e-05 23.3 1.5 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 GAX22999.1 - 0.0042 17.1 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAX22999.1 - 0.0061 16.8 0.2 0.024 14.9 0.0 2.1 2 1 0 2 2 2 1 PAS domain PAS_8 PF13188.7 GAX22999.1 - 0.0089 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain Mcm10 PF09332.11 GAX22999.1 - 0.013 15.0 5.3 0.013 15.0 5.3 1.5 2 0 0 2 2 2 0 Mcm10 replication factor DUF4778 PF16008.5 GAX22999.1 - 1.3 9.0 6.1 0.62 10.1 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) PIN_8 PF18476.1 GAX22999.1 - 5.2 6.9 7.9 4.2 7.2 6.3 1.6 2 0 0 2 2 2 0 PIN like domain Glyco_hydro_18 PF00704.28 GAX23000.1 - 7.3e-31 108.0 0.1 9.1e-31 107.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SBF PF01758.16 GAX23001.1 - 5.8e-25 88.1 8.3 5.8e-25 88.1 8.3 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 GAX23001.1 - 1.4e-10 41.0 18.2 2e-10 40.5 18.2 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 GAX23001.1 - 0.00012 20.6 11.3 0.00015 20.3 2.9 2.5 1 1 2 3 3 3 2 Membrane transport protein DUF445 PF04286.12 GAX23002.1 - 6.9e-16 59.0 1.3 0.00037 20.4 0.0 4.2 2 2 2 4 4 4 4 Protein of unknown function (DUF445) PRANC PF09372.10 GAX23002.1 - 0.051 13.9 0.5 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 PRANC domain adh_short PF00106.25 GAX23003.1 - 1.8e-31 109.2 0.1 3.3e-31 108.3 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX23003.1 - 2.2e-26 92.9 0.0 3.3e-26 92.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX23003.1 - 1.8e-05 24.7 0.1 2.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX23003.1 - 0.00011 21.8 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX23003.1 - 0.0009 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TMEM151 PF14857.6 GAX23004.1 - 4.6e-05 22.5 5.5 0.0069 15.4 1.0 2.3 2 0 0 2 2 2 2 TMEM151 family FKBP_C PF00254.28 GAX23005.1 - 1.4e-30 105.4 0.0 2.4e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Linker_histone PF00538.19 GAX23005.1 - 5.1e-08 33.2 0.5 8.8e-08 32.4 0.5 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family FA_desaturase PF00487.24 GAX23006.1 - 7.2e-26 91.5 21.2 2.1e-25 90.0 21.2 2.0 1 1 0 1 1 1 1 Fatty acid desaturase FA_hydroxylase PF04116.13 GAX23006.1 - 0.053 13.9 0.9 0.053 13.9 0.9 3.4 4 0 0 4 4 4 0 Fatty acid hydroxylase superfamily SBF PF01758.16 GAX23007.1 - 1.3e-25 90.3 9.8 1.3e-25 90.3 9.8 2.2 1 1 1 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 GAX23007.1 - 9.8e-05 20.9 10.4 0.00065 18.2 4.2 2.2 2 0 0 2 2 2 2 Membrane transport protein Holin_BlyA PF05102.12 GAX23007.1 - 3.2 7.8 4.9 5.9 6.9 0.2 2.7 3 0 0 3 3 3 0 holin, BlyA family GAF PF01590.26 GAX23008.1 - 1.1e-07 32.5 0.1 2.8e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 GAF domain DUF2461 PF09365.10 GAX23008.1 - 0.055 13.4 0.3 0.083 12.8 0.3 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Phage_GPD PF05954.11 GAX23008.1 - 0.14 11.4 0.4 0.33 10.2 0.1 1.7 1 1 1 2 2 2 0 Phage late control gene D protein (GPD) CLPTM1 PF05602.12 GAX23009.1 - 3.7e-66 223.9 1.3 1.7e-62 211.9 0.3 3.9 2 1 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 GAX23009.1 - 0.00013 21.7 0.8 0.22 11.3 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF3464 PF11947.8 GAX23009.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MNHE PF01899.16 GAX23009.1 - 0.64 9.8 3.1 0.41 10.4 0.1 2.2 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Cupin_2 PF07883.11 GAX23010.1 - 4.1e-05 23.2 0.2 0.00018 21.1 0.1 1.9 1 1 0 2 2 2 1 Cupin domain PRKCSH PF07915.13 GAX23011.1 - 2.4e-18 66.9 0.2 3.7e-10 40.7 0.0 2.8 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 GAX23011.1 - 1.2e-07 31.6 2.6 0.0023 17.6 0.3 4.6 4 1 0 4 4 4 2 Glucosidase II beta subunit-like protein GFA PF04828.14 GAX23013.1 - 1.2e-11 44.7 1.2 1.8e-11 44.2 1.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fer2_3 PF13085.6 GAX23013.1 - 0.0065 16.5 0.4 0.012 15.6 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DOT1 PF08123.13 GAX23014.1 - 0.032 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 GAX23014.1 - 0.096 13.4 0.0 0.32 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain EcKinase PF02958.20 GAX23015.1 - 5.4e-20 71.9 0.5 8.6e-20 71.2 0.5 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 GAX23015.1 - 8.4e-10 38.1 0.5 1.3e-09 37.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 GAX23015.1 - 7.8e-09 35.8 1.2 1.4e-08 34.9 1.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family SufE PF02657.15 GAX23017.1 - 9.3e-30 103.0 0.0 1.2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Fe-S metabolism associated domain SufE PF02657.15 GAX23018.1 - 3e-27 94.9 0.0 4e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Fe-S metabolism associated domain DUF1177 PF06675.11 GAX23018.1 - 0.067 12.0 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) SufE PF02657.15 GAX23019.1 - 1.8e-31 108.5 0.0 3.3e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 GAX23019.1 - 5.5e-26 90.7 0.1 9.5e-26 89.9 0.1 1.4 1 0 0 1 1 1 1 BolA-like protein UPF0020 PF01170.18 GAX23020.1 - 1.4e-26 93.4 0.0 1.9e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 GAX23020.1 - 2.1e-05 24.0 0.1 0.013 14.8 0.0 2.5 2 1 0 2 2 2 2 N-6 DNA Methylase N6_N4_Mtase PF01555.18 GAX23020.1 - 0.029 14.1 0.0 0.17 11.6 0.0 2.3 2 1 0 2 2 2 0 DNA methylase Kinetochor_Ybp2 PF08568.10 GAX23020.1 - 0.044 12.3 0.0 0.07 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Creb_binding PF09030.10 GAX23021.1 - 0.0045 17.7 0.0 0.0081 16.8 0.0 1.4 1 0 0 1 1 1 1 Creb binding Retro_M PF02813.14 GAX23021.1 - 0.048 14.1 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral M domain Peptidase_C48 PF02902.19 GAX23023.1 - 2.4e-33 115.8 1.2 2.4e-33 115.8 1.2 1.9 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain SWIB PF02201.18 GAX23026.1 - 8.3e-11 41.6 0.0 2.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain PhyH PF05721.13 GAX23027.1 - 8.4e-16 58.9 0.0 1.2e-15 58.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Hint_2 PF13403.6 GAX23027.1 - 0.05 13.9 0.1 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Hint domain PfkB PF00294.24 GAX23029.1 - 1.3e-08 34.6 0.0 8.1e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase EB1 PF03271.17 GAX23031.1 - 1.4e-11 44.5 0.7 3.4e-11 43.2 0.7 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 GAX23031.1 - 1.3e-06 28.6 0.4 9.3e-06 25.8 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain ERM PF00769.19 GAX23031.1 - 0.0027 17.6 2.9 0.004 17.0 2.9 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family JIP_LZII PF16471.5 GAX23031.1 - 0.0095 16.1 5.6 0.023 14.8 5.6 1.7 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II HALZ PF02183.18 GAX23031.1 - 0.018 15.2 5.1 0.19 12.0 2.4 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper CAMSAP_CH PF11971.8 GAX23031.1 - 0.031 14.1 0.1 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 CAMSAP CH domain APG6_N PF17675.1 GAX23031.1 - 0.044 14.3 8.6 0.084 13.4 8.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 GAX23031.1 - 0.061 13.8 9.6 4.9 7.7 9.6 2.5 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 GAX23031.1 - 0.061 13.4 4.3 0.13 12.3 2.5 2.3 2 1 1 3 3 3 0 bZIP transcription factor Mod_r PF07200.13 GAX23031.1 - 0.38 10.8 9.7 0.11 12.6 6.6 1.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 GAX23031.1 - 2.5 8.8 6.1 24 5.7 5.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF4954 PF16314.5 GAX23032.1 - 1.5e-23 82.8 0.0 7e-23 80.6 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) DUF924 PF06041.11 GAX23033.1 - 1.1e-40 139.7 0.0 1.3e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Sulfotransfer_4 PF17784.1 GAX23034.1 - 3.4e-42 144.7 0.0 5.5e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX23034.1 - 0.0016 18.9 0.1 0.041 14.2 0.1 2.5 1 1 0 1 1 1 1 Sulfotransferase family IRF-3 PF10401.9 GAX23034.1 - 0.0044 16.8 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 SURF1 PF02104.15 GAX23035.1 - 1e-32 113.8 0.1 2e-32 112.9 0.1 1.5 1 0 0 1 1 1 1 SURF1 family Cupin_3 PF05899.12 GAX23035.1 - 1.3e-31 108.1 4.5 2.7e-16 59.0 0.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GAX23035.1 - 1.1e-12 47.5 0.1 1.6e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 GAX23035.1 - 0.011 15.3 0.0 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Cupin AraC_binding PF02311.19 GAX23035.1 - 0.024 14.5 0.5 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain EutQ PF06249.12 GAX23035.1 - 0.044 13.5 0.0 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ TPR_2 PF07719.17 GAX23036.1 - 0.0003 20.7 0.0 0.0032 17.5 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23036.1 - 0.043 14.0 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23036.1 - 0.094 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat XhoI PF04555.13 GAX23037.1 - 0.043 13.7 0.1 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease XhoI Carboxyl_trans PF01039.22 GAX23039.1 - 1e-142 476.3 0.0 1.4e-142 475.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 GAX23039.1 - 0.0091 15.3 0.1 0.032 13.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Sdh_cyt PF01127.22 GAX23040.1 - 0.00027 20.9 7.5 0.0022 18.0 0.5 2.2 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Tmemb_18A PF09771.9 GAX23040.1 - 0.045 14.2 0.8 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 188 DUF4405 PF14358.6 GAX23040.1 - 0.21 12.2 0.3 0.21 12.2 0.3 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) Keratin_B2_2 PF13885.6 GAX23042.1 - 9.6e-05 22.3 0.0 0.64 10.0 0.0 3.0 2 1 1 3 3 3 2 Keratin, high sulfur B2 protein Sod_Cu PF00080.20 GAX23042.1 - 0.16 12.2 9.7 4.6 7.4 1.7 3.3 2 2 0 2 2 2 0 Copper/zinc superoxide dismutase (SODC) Keratin_B2 PF01500.17 GAX23042.1 - 0.43 10.5 7.4 0.2 11.6 1.9 2.9 2 1 0 2 2 2 0 Keratin, high sulfur B2 protein FAP PF07174.11 GAX23042.1 - 0.59 9.5 11.1 2.5 7.5 11.1 1.8 1 1 0 1 1 1 0 Fibronectin-attachment protein (FAP) AAA_2 PF07724.14 GAX23044.1 - 2.5e-38 131.9 0.0 4e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAX23044.1 - 9.3e-11 42.3 0.0 2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAX23044.1 - 5.9e-10 39.1 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 GAX23044.1 - 6.1e-05 22.2 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 GAX23044.1 - 8.5e-05 22.8 0.1 0.0014 18.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAX23044.1 - 0.00088 19.3 0.2 0.0029 17.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAX23044.1 - 0.003 18.1 0.0 0.0072 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX23044.1 - 0.004 17.6 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 GAX23044.1 - 0.0048 17.4 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Mg_chelatase PF01078.21 GAX23044.1 - 0.005 16.2 0.0 0.026 13.9 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 GAX23044.1 - 0.008 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TF_Zn_Ribbon PF08271.12 GAX23044.1 - 0.0098 15.4 0.3 0.023 14.2 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding AAA_29 PF13555.6 GAX23044.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 GAX23044.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Lar_restr_allev PF14354.6 GAX23044.1 - 0.021 15.2 0.8 0.047 14.1 0.8 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 GAX23044.1 - 0.059 13.3 2.3 0.11 12.5 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-TFIIB PF13453.6 GAX23044.1 - 0.061 12.7 0.4 0.16 11.3 0.4 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_7 PF12775.7 GAX23044.1 - 0.063 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 GAX23044.1 - 0.063 13.2 0.1 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 GAX23044.1 - 0.096 12.4 0.0 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 GAX23044.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 GAX23044.1 - 0.11 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-C4_Topoisom PF01396.19 GAX23044.1 - 0.11 12.3 0.9 0.2 11.5 0.9 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Sigma54_activ_2 PF14532.6 GAX23044.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 GAX23044.1 - 0.15 11.8 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Cir_N PF10197.9 GAX23044.1 - 0.22 11.8 1.6 0.53 10.5 1.6 1.6 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Cons_hypoth698 PF03601.14 GAX23045.1 - 4.5e-49 167.0 8.3 8.1e-49 166.1 8.3 1.4 1 1 0 1 1 1 1 Conserved hypothetical protein 698 Med21 PF11221.8 GAX23046.1 - 1.2e-10 41.9 3.1 1.8e-10 41.3 3.1 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex RINT1_TIP1 PF04437.13 GAX23046.1 - 0.0092 14.9 0.1 0.012 14.5 0.1 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Zea_mays_MuDR PF05928.11 GAX23046.1 - 0.021 14.5 0.8 0.072 12.7 0.3 2.0 1 1 1 2 2 2 0 Zea mays MURB-like protein (MuDR) Med9 PF07544.13 GAX23046.1 - 0.028 14.5 1.4 0.12 12.5 0.4 2.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Aa_trans PF01490.18 GAX23047.1 - 2.8e-61 207.4 14.4 3.3e-61 207.2 14.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAX23047.1 - 0.00087 18.4 1.3 0.00087 18.4 1.3 2.3 3 1 0 3 3 3 1 Tryptophan/tyrosine permease family Peptidase_M3 PF01432.20 GAX23048.1 - 5.7e-117 391.8 4.1 8.3e-117 391.2 4.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 DUF3138 PF11336.8 GAX23048.1 - 0.057 12.0 1.9 0.087 11.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) UPF0176_N PF17773.1 GAX23049.1 - 2.2e-16 60.0 0.0 2.6e-15 56.5 0.0 2.5 3 0 0 3 3 3 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GAX23049.1 - 3.4e-06 27.5 0.0 7.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 GAX23049.1 - 0.0002 21.7 0.7 0.00067 20.0 0.7 1.9 1 1 0 1 1 1 1 Rhodanase C-terminal SATase_N PF06426.14 GAX23051.1 - 0.071 13.5 3.5 0.074 13.4 1.7 1.9 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal DUF4998 PF16389.5 GAX23051.1 - 0.097 12.2 1.0 0.17 11.4 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function ISP3_C PF18045.1 GAX23051.1 - 0.35 10.7 5.2 3.2 7.7 0.5 2.4 1 1 1 2 2 2 0 ISP3 C-terminal Endotoxin_N PF03945.14 GAX23051.1 - 1.1 8.9 3.9 0.73 9.5 2.1 1.6 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain DUF2732 PF10809.8 GAX23051.1 - 1.3 8.9 16.6 0.52 10.2 1.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2732) V_ATPase_I PF01496.19 GAX23051.1 - 3.1 5.6 11.4 3.2 5.5 11.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_14 PF13428.6 GAX23052.1 - 0.93 10.5 5.9 0.53 11.2 0.5 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX23053.1 - 0.03 14.7 0.0 2.9 8.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PXA PF02194.15 GAX23054.1 - 3e-21 76.2 0.0 2.7e-16 60.1 0.0 2.6 2 0 0 2 2 2 2 PXA domain Nexin_C PF08628.12 GAX23054.1 - 9.9e-11 42.2 0.0 3.2e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 GAX23054.1 - 0.00023 21.1 0.0 0.00065 19.7 0.0 1.8 1 0 0 1 1 1 1 PX domain zf-MYND PF01753.18 GAX23055.1 - 0.63 10.2 15.3 0.031 14.4 7.4 2.6 2 0 0 2 2 2 0 MYND finger TPR_12 PF13424.6 GAX23056.1 - 4.8e-29 100.5 8.9 1.1e-09 38.5 0.1 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX23056.1 - 8.2e-20 70.0 9.1 1.1e-05 25.1 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23056.1 - 2.2e-18 65.2 13.0 7.5e-07 28.7 1.5 5.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23056.1 - 3e-18 64.4 11.6 0.00019 21.2 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX23056.1 - 8.9e-17 59.8 10.4 9.1e-07 28.5 0.8 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23056.1 - 2.5e-14 52.2 12.9 4.8e-05 23.2 0.2 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX23056.1 - 8.4e-13 48.0 1.4 0.0062 17.3 0.1 5.1 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23056.1 - 4.8e-10 39.4 9.1 0.12 13.1 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX23056.1 - 2.3e-07 30.5 12.0 0.00036 20.0 0.7 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_19 PF14559.6 GAX23056.1 - 3.9e-07 30.5 10.5 0.00072 20.0 0.4 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX23056.1 - 3e-06 26.8 0.3 3e-06 26.8 0.3 4.4 4 2 2 6 6 5 2 TPR repeat TPR_16 PF13432.6 GAX23056.1 - 1.2e-05 25.8 3.0 0.1 13.3 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX23056.1 - 2.1e-05 24.6 4.7 2.1 8.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.9 GAX23056.1 - 0.0011 18.7 5.5 0.13 12.0 0.1 3.6 2 2 2 4 4 4 2 26S proteasome subunit RPN7 TPR_4 PF07721.14 GAX23056.1 - 0.0018 18.7 0.0 19 6.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 GAX23056.1 - 0.0027 17.8 1.3 2.8 8.4 0.1 3.2 2 0 0 2 2 2 1 PPR repeat DUF4810 PF16068.5 GAX23056.1 - 0.028 14.9 8.6 1.9 9.1 0.2 4.2 3 1 2 5 5 5 0 Domain of unknown function (DUF4810) ApbE PF02424.15 GAX23056.1 - 0.05 13.1 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 ApbE family TPR_9 PF13371.6 GAX23056.1 - 0.088 13.0 1.7 1.1 9.4 0.0 3.1 3 1 1 4 4 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAX23056.1 - 0.095 12.7 2.8 0.73 9.8 0.2 2.9 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 BTAD PF03704.17 GAX23056.1 - 0.097 13.1 5.7 7.1 7.1 1.4 3.3 2 1 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.18 GAX23056.1 - 0.24 11.5 8.5 1.6 8.9 1.5 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 GAX23056.1 - 0.33 10.7 8.7 0.72 9.5 0.2 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain DUF5113 PF17140.4 GAX23056.1 - 0.49 10.2 5.7 14 5.5 0.0 4.1 2 1 1 4 4 4 0 Domain of unknown function (DUF5113) KxDL PF10241.9 GAX23057.1 - 0.29 11.5 12.4 2.1 8.6 6.5 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein Cep57_CLD_2 PF14197.6 GAX23057.1 - 0.32 11.1 12.2 30 4.8 12.1 2.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 BLOC1_2 PF10046.9 GAX23057.1 - 0.35 11.2 16.6 0.43 10.9 1.9 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0449 PF15136.6 GAX23057.1 - 5.8 7.4 13.3 21 5.6 8.5 3.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF1664 PF07889.12 GAX23057.1 - 8 6.5 14.1 3.2 7.8 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 GAX23057.1 - 8.6 5.5 10.9 4.5 6.4 8.8 1.5 1 1 0 1 1 1 0 TMPIT-like protein IQ PF00612.27 GAX23058.1 - 0.0078 15.9 2.5 0.019 14.7 2.5 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Exonuc_VII_L PF02601.15 GAX23058.1 - 1.1 8.8 8.5 1.9 8.0 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 GAX23058.1 - 2.4 8.3 19.9 0.028 14.6 7.8 2.6 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 ETRAMP PF09716.10 GAX23058.1 - 7.8 6.6 9.0 15 5.7 0.7 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MCR_C PF04609.12 GAX23059.1 - 0.0031 16.6 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyl-coenzyme M reductase operon protein C FSAP_sig_propep PF03032.15 GAX23059.1 - 1.4 9.0 12.6 3.5 7.7 12.6 1.7 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide bZIP_1 PF00170.21 GAX23060.1 - 0.001 19.1 14.0 0.073 13.2 2.3 3.5 2 1 0 3 3 3 2 bZIP transcription factor DUF812 PF05667.11 GAX23060.1 - 0.0011 17.9 14.1 0.0014 17.6 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GAS PF13851.6 GAX23060.1 - 0.0037 16.6 20.7 0.13 11.6 12.1 2.4 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 GAX23060.1 - 0.0039 17.1 15.5 0.0076 16.1 15.5 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 GAX23060.1 - 0.0047 16.3 9.9 0.0047 16.3 9.9 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3450) IQ PF00612.27 GAX23060.1 - 0.0086 15.8 1.5 0.025 14.4 1.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif CENP-F_leu_zip PF10473.9 GAX23060.1 - 0.0087 16.1 15.1 0.0087 16.1 15.1 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 GAX23060.1 - 0.011 14.6 2.5 0.011 14.6 2.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Hemerythrin PF01814.23 GAX23060.1 - 0.027 15.1 2.7 0.027 15.1 2.7 2.0 2 0 0 2 2 1 0 Hemerythrin HHE cation binding domain HOOK PF05622.12 GAX23060.1 - 0.028 12.6 19.0 0.0096 14.1 14.4 1.9 1 1 1 2 2 2 0 HOOK protein DUF3584 PF12128.8 GAX23060.1 - 0.041 11.4 20.7 0.055 11.0 20.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.8 GAX23060.1 - 0.042 13.8 11.8 0.077 13.0 8.8 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 GAX23060.1 - 0.047 14.1 6.7 0.047 14.1 6.7 3.3 1 1 2 3 3 3 0 Cell division protein ZapB Plk4_PB2 PF18409.1 GAX23060.1 - 0.051 14.3 6.2 0.051 14.2 0.5 3.0 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 SPATA1_C PF15743.5 GAX23060.1 - 0.059 13.4 22.0 0.37 10.9 13.1 2.4 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus Macoilin PF09726.9 GAX23060.1 - 0.06 11.9 12.9 0.076 11.6 12.9 1.1 1 0 0 1 1 1 0 Macoilin family Shugoshin_N PF07558.11 GAX23060.1 - 0.085 12.7 3.8 4.2 7.3 3.0 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NRBF2 PF08961.10 GAX23060.1 - 0.089 12.4 10.2 0.11 12.1 9.1 1.8 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TMF_TATA_bd PF12325.8 GAX23060.1 - 0.12 12.6 16.8 0.031 14.5 11.3 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mer2 PF09074.10 GAX23060.1 - 0.14 12.0 8.9 0.041 13.7 5.3 1.8 1 1 1 2 2 2 0 Mer2 ATG16 PF08614.11 GAX23060.1 - 0.18 12.0 21.8 1.3 9.2 21.8 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 GAX23060.1 - 0.26 11.6 9.4 0.27 11.6 0.8 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoO PF09769.9 GAX23060.1 - 0.27 11.2 4.5 0.95 9.4 0.4 2.5 1 1 0 2 2 2 0 Apolipoprotein O Rootletin PF15035.6 GAX23060.1 - 0.3 11.1 19.3 0.47 10.4 13.1 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Peptidase_S64 PF08192.11 GAX23060.1 - 0.31 9.5 7.7 0.46 8.9 7.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF1664 PF07889.12 GAX23060.1 - 0.32 11.0 10.0 0.17 11.9 3.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 GAX23060.1 - 0.37 11.4 14.4 1.3 9.7 0.9 3.3 2 1 1 3 3 3 0 SlyX DASH_Dam1 PF08653.10 GAX23060.1 - 0.38 10.6 5.4 1.2 9.0 0.6 2.7 2 1 1 3 3 2 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 GAX23060.1 - 0.39 10.9 12.8 0.93 9.7 0.5 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 GAX23060.1 - 0.4 11.1 7.7 11 6.5 0.5 3.8 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 GAX23060.1 - 0.47 10.8 16.2 0.66 10.3 8.0 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) YabA PF06156.13 GAX23060.1 - 0.66 10.7 14.1 3.8 8.2 5.0 3.2 2 1 2 4 4 3 0 Initiation control protein YabA UPF0242 PF06785.11 GAX23060.1 - 0.71 9.9 17.6 0.26 11.4 14.8 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF5082 PF16888.5 GAX23060.1 - 0.83 9.9 13.1 9.6 6.5 7.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Sec20 PF03908.13 GAX23060.1 - 0.99 9.4 5.3 0.77 9.7 1.3 2.6 2 1 1 3 3 2 0 Sec20 Wtap PF17098.5 GAX23060.1 - 1.1 9.2 13.9 9.4 6.1 13.9 2.4 1 1 0 1 1 1 0 WTAP/Mum2p family HALZ PF02183.18 GAX23060.1 - 1.2 9.4 7.9 1.6 9.0 3.3 3.0 1 1 2 3 3 3 0 Homeobox associated leucine zipper FliJ PF02050.16 GAX23060.1 - 1.4 9.1 25.8 7 6.9 13.5 3.5 1 1 1 2 2 2 0 Flagellar FliJ protein COG2 PF06148.11 GAX23060.1 - 1.5 9.0 11.1 0.24 11.5 4.2 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 USP8_interact PF08941.10 GAX23060.1 - 1.6 8.5 7.5 0.55 10.0 2.8 2.2 1 1 2 3 3 2 0 USP8 interacting Laminin_II PF06009.12 GAX23060.1 - 1.8 8.5 14.1 2.7 8.0 2.1 2.7 1 1 1 2 2 2 0 Laminin Domain II Phage_GP20 PF06810.11 GAX23060.1 - 1.9 8.2 18.2 0.82 9.5 10.7 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 TMPIT PF07851.13 GAX23060.1 - 2.3 7.4 15.0 0.043 13.1 5.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein Uso1_p115_C PF04871.13 GAX23060.1 - 2.4 8.6 23.3 9.4 6.6 8.8 3.3 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 GAX23060.1 - 2.7 7.8 21.7 0.16 11.7 5.9 3.5 2 1 2 4 4 4 0 Septum formation initiator APG6_N PF17675.1 GAX23060.1 - 3.6 8.1 23.8 29 5.2 23.8 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1640 PF07798.11 GAX23060.1 - 4.4 7.3 18.2 18 5.3 16.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF948 PF06103.11 GAX23060.1 - 4.9 7.5 8.4 2 8.7 3.0 2.8 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Cnn_1N PF07989.11 GAX23060.1 - 5.8 7.2 18.9 21 5.4 10.0 3.3 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 V_ATPase_I PF01496.19 GAX23060.1 - 9.9 3.9 11.9 13 3.5 11.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AcetylCoA_hyd_C PF13336.6 GAX23061.1 - 8.6e-47 158.9 0.0 1.3e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 GAX23061.1 - 7.3e-12 45.7 0.0 1.4e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Mal_decarbox_Al PF16957.5 GAX23061.1 - 0.17 10.2 0.0 0.26 9.6 0.0 1.1 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Heme_oxygenase PF01126.20 GAX23062.1 - 7.3e-55 185.9 0.1 9.5e-55 185.6 0.1 1.1 1 0 0 1 1 1 1 Heme oxygenase Apolipo_F PF15148.6 GAX23062.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein F Med15_fungi PF05397.12 GAX23062.1 - 0.1 12.9 0.0 5.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 15 Glyco_hydro_18 PF00704.28 GAX23063.1 - 1.3e-15 58.0 0.1 2.3e-15 57.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 GAX23063.1 - 1.9e-08 34.4 8.4 1.9e-08 34.4 8.4 2.6 3 0 0 3 3 3 1 Chitin binding Peritrophin-A domain BT1 PF03092.16 GAX23064.1 - 3.3e-57 193.9 8.3 6.4e-35 120.4 1.5 2.1 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 GAX23064.1 - 0.0011 18.0 0.5 0.0038 16.3 0.5 2.0 1 1 0 1 1 1 1 PUCC protein RWD PF05773.22 GAX23064.1 - 0.18 12.1 0.4 0.55 10.5 0.2 1.9 2 0 0 2 2 2 0 RWD domain PAS_9 PF13426.7 GAX23065.1 - 0.0031 17.8 0.0 0.0078 16.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 GAX23066.1 - 8.1e-05 22.6 0.4 0.0076 16.2 0.0 3.2 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 GAX23066.1 - 0.0038 17.5 0.0 0.075 13.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain RNA_pol_Rpb1_5 PF04998.17 GAX23067.1 - 1.3e-82 277.2 0.0 2.1e-82 276.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAX23067.1 - 1e-59 201.5 0.1 1.7e-59 200.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 GAX23067.1 - 1e-30 107.2 0.0 2.1e-30 106.1 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 GAX23067.1 - 5.6e-30 104.4 0.0 2.3e-29 102.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAX23067.1 - 9e-20 70.6 0.0 4.1e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 BUD22 PF09073.10 GAX23067.1 - 1.4 8.2 28.5 0.018 14.4 11.0 2.2 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 GAX23067.1 - 2.9 7.2 28.1 0.076 12.4 13.5 2.3 2 0 0 2 2 2 0 SDA1 SPT_ssu-like PF11779.8 GAX23068.1 - 0.0047 16.5 2.7 0.006 16.2 2.7 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Lactamase_B_2 PF12706.7 GAX23069.1 - 1.1e-28 100.2 0.5 5e-28 98.0 0.5 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAX23069.1 - 2e-12 47.3 0.0 2.1e-11 44.0 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Adaptin_N PF01602.20 GAX23070.1 - 1e-147 492.9 10.5 1.2e-147 492.7 10.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAX23070.1 - 2.3e-63 213.0 5.8 1.3e-62 210.6 0.0 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 GAX23070.1 - 2e-27 95.5 0.2 1.2e-26 93.0 0.0 2.3 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 GAX23070.1 - 2.9e-17 62.8 11.5 3.2e-06 27.4 0.1 5.7 3 1 2 5 5 5 5 HEAT repeats HEAT PF02985.22 GAX23070.1 - 1.4e-08 34.2 4.2 0.028 14.7 0.1 6.0 5 0 0 5 5 5 2 HEAT repeat Cnd3 PF12719.7 GAX23070.1 - 9.5e-05 21.7 1.6 0.028 13.6 0.2 3.2 2 1 2 4 4 4 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 GAX23070.1 - 0.00034 20.7 3.3 4.8 7.4 0.0 4.8 2 2 2 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 GAX23070.1 - 0.0012 18.7 1.8 0.0066 16.4 0.1 2.8 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal UNC45-central PF11701.8 GAX23070.1 - 0.0022 18.0 0.2 0.35 10.8 0.0 3.1 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Alpha_adaptinC2 PF02883.20 GAX23070.1 - 0.0024 18.2 1.4 0.0049 17.2 1.4 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_EZ PF13513.6 GAX23070.1 - 0.0074 16.8 7.0 40 4.9 0.0 5.9 6 0 0 6 6 6 0 HEAT-like repeat Arm_2 PF04826.13 GAX23070.1 - 0.02 14.4 0.0 0.02 14.4 0.0 3.1 4 0 0 4 4 4 0 Armadillo-like Arm PF00514.23 GAX23070.1 - 0.034 14.2 1.6 28 4.9 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 GAX23070.1 - 0.08 12.5 1.1 5.3 6.5 0.0 3.1 3 1 0 3 3 3 0 CLASP N terminal DHHC PF01529.20 GAX23071.1 - 1.7e-30 105.8 16.8 1.7e-30 105.8 16.8 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Zf_RING PF16744.5 GAX23071.1 - 0.076 13.1 4.2 0.2 11.8 4.2 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger PBP1_TM PF14812.6 GAX23071.1 - 0.56 10.6 6.5 1.3 9.4 6.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myosin_head PF00063.21 GAX23074.1 - 6.6e-154 513.7 0.0 1.1e-153 513.1 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 GAX23074.1 - 9e-06 25.1 23.7 0.052 13.4 0.1 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_16 PF13191.6 GAX23074.1 - 0.0022 18.4 0.1 0.0094 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX23074.1 - 0.021 15.1 0.0 0.077 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 GAX23074.1 - 0.097 11.6 0.2 0.27 10.1 0.0 1.8 3 0 0 3 3 3 0 AAA-like domain AAA_19 PF13245.6 GAX23074.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAX23074.1 - 0.18 11.1 1.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin HOOK PF05622.12 GAX23075.1 - 0.012 13.8 11.9 0.02 13.0 11.9 1.2 1 0 0 1 1 1 0 HOOK protein Cnn_1N PF07989.11 GAX23075.1 - 0.36 11.0 8.0 0.24 11.6 3.4 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 PPV_E1_N PF00524.18 GAX23075.1 - 0.59 10.6 5.9 1.2 9.6 1.5 3.3 2 1 1 3 3 3 0 E1 Protein, N terminal domain PRKG1_interact PF15898.5 GAX23075.1 - 0.83 10.6 11.9 5.5 7.9 11.9 2.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Acyl-CoA_ox_N PF14749.6 GAX23075.1 - 1 9.9 6.9 1.7 9.2 4.8 2.4 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Bcr-Abl_Oligo PF09036.10 GAX23075.1 - 1.4 8.9 9.5 0.19 11.8 0.5 3.4 4 0 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain DUF724 PF05266.14 GAX23075.1 - 2.2 8.1 12.0 0.73 9.6 8.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 GAX23075.1 - 7.1 6.7 20.1 2 8.5 4.6 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MIT PF04212.18 GAX23076.1 - 0.0054 16.8 2.5 0.075 13.1 0.0 3.4 2 2 1 3 3 3 1 MIT (microtubule interacting and transport) domain MEF2_binding PF09047.10 GAX23076.1 - 0.031 14.1 0.9 0.047 13.5 0.0 1.7 2 0 0 2 2 2 0 MEF2 binding tRNA-synt_1e PF01406.19 GAX23077.1 - 3.3e-96 322.2 0.2 3.3e-96 322.2 0.2 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAX23077.1 - 2.5e-12 46.3 0.6 3.7e-07 29.2 0.4 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 GAX23077.1 - 6.1e-07 29.8 0.9 1.7e-06 28.4 0.1 2.2 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.18 GAX23077.1 - 9.6e-06 24.7 0.1 0.032 13.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 GAX23077.1 - 8.7e-05 21.0 0.0 0.0006 18.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) FlaF PF07309.11 GAX23077.1 - 0.073 13.1 0.0 5.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Flagellar protein FlaF DUF1664 PF07889.12 GAX23077.1 - 0.68 10.0 3.5 0.5 10.4 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_M24 PF00557.24 GAX23078.1 - 1e-46 159.3 0.0 1.3e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.25 GAX23079.1 - 2.6e-31 109.0 0.0 3.5e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23079.1 - 4.5e-19 68.7 0.0 6.2e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX23079.1 - 0.00015 21.2 0.1 0.00031 20.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX23079.1 - 0.0031 17.5 0.1 0.0092 15.9 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX23079.1 - 0.0035 16.2 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DEAD PF00270.29 GAX23080.1 - 1.3e-45 155.3 0.0 2.3e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX23080.1 - 3.4e-28 98.2 0.0 3.1e-27 95.1 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX23080.1 - 0.00025 21.1 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAX23080.1 - 0.00068 18.5 0.0 0.64 8.7 0.0 2.6 2 1 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 GAX23080.1 - 0.018 14.2 0.1 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 GAX23080.1 - 0.15 12.3 0.7 0.8 10.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 GAX23081.1 - 2.9e-30 105.5 0.0 4.6e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23081.1 - 1.4e-29 103.2 0.0 3.3e-29 102.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX23081.1 - 0.00022 20.2 0.0 0.00041 19.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase SR-25 PF10500.9 GAX23081.1 - 1 9.0 7.9 2 8.0 7.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_tranf_2_4 PF13704.6 GAX23084.1 - 0.00096 19.6 0.0 0.0027 18.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 zf-RING_2 PF13639.6 GAX23085.1 - 0.011 16.1 13.0 0.02 15.2 13.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 GAX23085.1 - 0.013 15.5 6.2 0.019 15.0 5.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger Siva PF05458.12 GAX23085.1 - 0.24 11.0 5.8 0.44 10.2 5.8 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Ribosomal_S27e PF01667.17 GAX23085.1 - 0.59 9.9 6.8 4.4 7.1 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 zf-C3HC4 PF00097.25 GAX23085.1 - 1.7 8.5 14.4 3.3 7.7 14.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GAX23085.1 - 2 8.3 11.3 5 7.0 11.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 GAX23085.1 - 3 8.1 11.3 6.9 6.9 11.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger PHD_4 PF16866.5 GAX23085.1 - 7.4 6.7 11.6 13 6.0 10.3 2.1 2 1 0 2 2 2 0 PHD-finger Cupin_8 PF13621.6 GAX23087.1 - 1.6e-19 70.6 1.3 6.1e-18 65.4 0.2 2.4 2 1 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 GAX23087.1 - 0.0048 16.4 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Globin PF00042.22 GAX23088.1 - 3.4e-15 56.5 0.0 4.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Globin FGE-sulfatase PF03781.16 GAX23089.1 - 1.9e-41 142.4 14.3 1.9e-41 142.4 14.3 3.0 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 Zn_Tnp_IS1 PF03811.13 GAX23089.1 - 0.16 11.7 0.8 4.6 7.0 0.1 2.4 2 0 0 2 2 2 0 InsA N-terminal domain Med19 PF10278.9 GAX23089.1 - 9.4 6.1 7.4 8.3 6.3 4.2 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF2695 PF10905.8 GAX23090.1 - 0.018 15.3 0.4 0.15 12.3 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) Strep_SA_rep PF06696.11 GAX23090.1 - 0.037 14.0 1.3 0.14 12.2 0.1 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Peptidase_S10 PF00450.22 GAX23091.1 - 2.8e-118 396.0 2.1 2.8e-118 395.9 1.5 1.2 1 1 0 1 1 1 1 Serine carboxypeptidase TPR_1 PF00515.28 GAX23092.1 - 7.3e-07 28.8 0.2 0.0042 16.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23092.1 - 0.0028 17.9 2.4 0.36 11.1 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat SAM35 PF10806.8 GAX23092.1 - 0.009 16.3 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex TPR_2 PF07719.17 GAX23092.1 - 0.016 15.3 0.5 0.37 11.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX23092.1 - 0.11 13.0 4.0 2.2 8.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX23092.1 - 0.94 9.4 6.1 26 4.8 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Nrap_D3 PF17404.2 GAX23093.1 - 2.1e-32 112.4 0.0 2.1e-31 109.2 0.0 2.5 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D5 PF17406.2 GAX23093.1 - 1.4e-30 106.2 0.0 3.5e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 GAX23093.1 - 1.2e-27 96.7 0.1 3.2e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 GAX23093.1 - 2.2e-18 66.8 1.5 4.6e-18 65.7 1.5 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 GAX23093.1 - 5.6e-15 55.4 0.0 6.8e-10 38.9 0.0 3.2 3 0 0 3 3 3 2 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 GAX23093.1 - 7.3e-12 45.7 0.0 1.5e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 PAP_central PF04928.17 GAX23093.1 - 0.032 13.2 0.0 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain DnaJ PF00226.31 GAX23094.1 - 9.8e-29 99.3 4.1 4.1e-28 97.3 4.1 2.2 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 GAX23094.1 - 1.5e-23 81.0 30.6 1.8e-07 30.8 0.9 9.4 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23094.1 - 1.9e-22 78.1 24.4 2.8e-08 33.2 0.3 9.2 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23094.1 - 5.2e-18 63.7 14.5 8e-07 28.8 0.0 8.8 9 1 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23094.1 - 3.2e-17 61.2 22.1 0.00012 21.8 0.3 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23094.1 - 1e-16 61.0 20.9 0.00085 19.6 3.1 6.8 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAX23094.1 - 1.5e-15 57.5 27.9 0.00049 20.7 1.7 8.1 6 3 2 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX23094.1 - 1.4e-13 50.9 19.2 2.2e-07 31.0 0.4 5.4 4 2 1 5 5 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAX23094.1 - 5.3e-13 48.6 22.2 0.00056 20.5 0.1 8.4 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAX23094.1 - 3.6e-11 42.5 21.5 5.4e-05 22.8 0.0 8.0 6 2 2 8 8 8 4 TPR repeat TPR_19 PF14559.6 GAX23094.1 - 4e-10 40.0 16.4 0.006 17.1 0.4 6.5 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 GAX23094.1 - 1.3e-06 28.5 15.5 0.0028 17.7 0.5 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23094.1 - 2.5e-05 24.6 18.1 0.27 11.9 0.1 7.6 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAX23094.1 - 0.00012 22.3 12.7 0.31 11.8 0.8 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat PRAI PF00697.22 GAX23094.1 - 0.00044 20.1 2.5 0.00086 19.1 2.5 1.4 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF627 PF04781.12 GAX23094.1 - 0.0012 18.9 5.2 4.7 7.3 0.1 5.2 3 2 1 4 4 4 1 Protein of unknown function (DUF627) TPR_10 PF13374.6 GAX23094.1 - 0.0013 18.5 18.6 5.2 7.1 0.3 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX23094.1 - 0.0069 15.8 3.9 0.031 13.7 0.0 4.0 6 0 0 6 6 5 1 SHNi-TPR TPR_17 PF13431.6 GAX23094.1 - 0.021 15.2 12.4 0.081 13.3 0.1 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat MIT PF04212.18 GAX23094.1 - 0.029 14.4 22.9 0.7 10.0 0.9 6.5 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain SUKH-4 PF14435.6 GAX23094.1 - 0.044 13.8 0.3 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 SUKH-4 immunity protein DUF3627 PF12299.8 GAX23094.1 - 0.08 13.0 3.9 3.3 7.8 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) Sec23_trunk PF04811.15 GAX23094.1 - 0.13 11.9 0.5 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain TPR_3 PF07720.12 GAX23094.1 - 0.27 11.3 8.5 0.94 9.5 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.22 GAX23094.1 - 0.42 10.8 4.0 3.4 7.8 4.0 2.2 1 1 0 1 1 1 0 Ribosomal protein S8e DUF2330 PF10092.9 GAX23094.1 - 2.6 7.1 7.3 0.66 9.0 1.0 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2330) CorA PF01544.18 GAX23094.1 - 6.7 5.9 6.3 2 7.7 2.8 1.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein MscS_porin PF12795.7 GAX23095.1 - 0.0017 18.0 18.1 0.0017 18.0 18.1 9.2 2 2 7 9 9 9 3 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 GAX23095.1 - 0.0019 18.2 15.5 0.0019 18.2 15.5 11.3 3 3 8 11 11 11 3 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 GAX23095.1 - 0.0023 18.2 17.1 0.0023 18.2 17.1 10.9 1 1 7 9 9 9 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAX23095.1 - 0.0024 16.8 19.1 0.0024 16.8 19.1 10.2 1 1 7 10 10 10 5 Spc7 kinetochore protein KASH_CCD PF14662.6 GAX23095.1 - 0.0036 17.1 6.4 0.0036 17.1 6.4 9.4 1 1 6 9 9 9 1 Coiled-coil region of CCDC155 or KASH CHASE PF03924.13 GAX23096.1 - 0.014 15.3 0.7 0.91 9.4 0.2 2.6 2 0 0 2 2 2 0 CHASE domain Pox_A_type_inc PF04508.12 GAX23096.1 - 1.4 8.9 28.7 1.1 9.3 0.1 7.6 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat PAP_fibrillin PF04755.12 GAX23096.1 - 3.4 7.6 14.9 2.6 7.9 8.4 3.6 2 2 0 2 2 2 0 PAP_fibrillin MoaE PF02391.17 GAX23098.1 - 1.6e-35 121.8 0.1 2.3e-35 121.3 0.1 1.3 1 0 0 1 1 1 1 MoaE protein PAN_2 PF08276.11 GAX23098.1 - 0.11 12.6 1.0 0.22 11.7 0.8 1.5 1 1 0 1 1 1 0 PAN-like domain DRMBL PF07522.14 GAX23101.1 - 4.4e-24 84.8 0.3 1.1e-22 80.2 0.0 2.5 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GAX23101.1 - 2e-06 27.4 0.2 5.5e-06 26.0 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX23101.1 - 0.0055 16.7 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily C1_2 PF03107.16 GAX23101.1 - 0.54 10.6 3.0 8.8 6.7 0.3 3.3 3 0 0 3 3 3 0 C1 domain NOA36 PF06524.12 GAX23101.1 - 1.3 8.3 12.5 2.7 7.2 12.5 1.5 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 GAX23102.1 - 3.2e-63 213.6 0.0 6.1e-63 212.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23102.1 - 1.3e-30 106.6 0.0 2.1e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX23102.1 - 1.7e-05 24.3 0.0 6.1e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAX23102.1 - 0.00033 19.6 0.0 0.00033 19.6 0.0 2.4 3 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 GAX23102.1 - 0.00076 19.5 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX23102.1 - 0.0017 17.7 0.0 0.0051 16.2 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 GAX23102.1 - 0.031 15.0 7.6 0.034 14.9 0.3 3.6 3 0 0 3 3 3 0 Protein kinase C terminal domain FTA2 PF13095.6 GAX23102.1 - 0.055 13.1 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MORN PF02493.20 GAX23103.1 - 8.6e-34 113.4 31.6 2.9e-06 26.8 0.4 7.3 7 0 0 7 7 7 7 MORN repeat Response_reg PF00072.24 GAX23105.1 - 1e-18 67.5 0.1 6.1e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 GAX23105.1 - 0.0006 20.4 0.0 0.0015 19.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 GAX23105.1 - 0.0014 18.7 3.1 0.0016 18.4 1.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain RuvA_C PF07499.13 GAX23105.1 - 0.004 17.6 0.3 0.56 10.7 0.1 2.7 2 0 0 2 2 2 1 RuvA, C-terminal domain Sacchrp_dh_NADP PF03435.18 GAX23106.1 - 5.5e-12 46.1 0.0 9.1e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 GAX23106.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 KR domain UTP15_C PF09384.10 GAX23106.1 - 0.032 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 UTP15 C terminal Shikimate_DH PF01488.20 GAX23106.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RabGAP-TBC PF00566.18 GAX23107.1 - 4.1e-56 190.0 2.1 2.6e-48 164.5 0.2 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Bunya_NS-S PF01104.17 GAX23107.1 - 0.41 10.5 4.2 16 5.4 1.2 3.1 3 0 0 3 3 3 0 Bunyavirus non-structural protein NS-s TPR_12 PF13424.6 GAX23108.1 - 2.2e-11 43.9 0.7 2.3e-06 27.8 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23108.1 - 0.00029 20.6 1.0 0.99 9.6 0.3 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX23108.1 - 0.0023 18.4 0.0 0.19 12.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-ACC PF17848.1 GAX23108.1 - 0.011 15.8 2.1 0.02 14.9 0.2 2.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain TPR_12 PF13424.6 GAX23110.1 - 1.3e-29 102.3 24.8 1.9e-10 40.9 0.0 7.8 2 2 4 8 8 8 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAX23110.1 - 1.6e-12 46.9 13.8 0.0061 16.4 0.0 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX23110.1 - 2.7e-12 45.8 18.0 0.0057 16.7 0.1 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23110.1 - 1.2e-11 43.9 11.3 0.0004 20.1 0.2 7.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23110.1 - 9.9e-08 31.6 3.1 0.015 15.4 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX23110.1 - 4.1e-06 26.4 0.9 4.1e-06 26.4 0.9 3.1 2 2 1 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 GAX23110.1 - 4.7e-05 23.1 13.4 0.49 10.5 0.5 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat Ricin_B_lectin PF00652.22 GAX23110.1 - 0.0047 17.2 5.3 0.013 15.8 5.3 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain MIT PF04212.18 GAX23110.1 - 0.0092 16.0 14.4 2.1 8.5 0.2 6.4 6 1 1 7 7 7 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 GAX23110.1 - 0.016 14.9 7.5 2.7 7.7 0.2 4.7 5 0 0 5 5 5 0 TPR repeat DUF1824 PF08854.10 GAX23110.1 - 0.062 13.2 0.2 0.23 11.4 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) TPR_14 PF13428.6 GAX23110.1 - 0.21 12.5 14.8 6.4 7.9 0.3 6.1 5 2 2 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX23110.1 - 1.4 9.5 14.3 0.39 11.3 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX23110.1 - 1.9 9.2 9.5 46 4.8 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23110.1 - 2.7 8.8 23.6 4.4 8.1 0.0 7.8 8 1 0 8 8 8 0 Tetratricopeptide repeat MoaC PF01967.21 GAX23111.1 - 1.8e-44 151.1 4.3 3e-44 150.4 4.3 1.4 1 0 0 1 1 1 1 MoaC family MazG-like PF12643.7 GAX23111.1 - 1.1e-06 28.7 0.5 0.00029 21.0 0.0 2.5 2 0 0 2 2 2 2 MazG-like family MazG PF03819.17 GAX23111.1 - 0.055 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Zip PF02535.22 GAX23111.1 - 0.31 10.2 11.9 1.1 8.4 7.7 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2946 PF11162.8 GAX23111.1 - 6.9 7.4 9.0 1.6 9.4 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) GST_N_3 PF13417.6 GAX23112.1 - 8.8e-12 45.3 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX23112.1 - 2.6e-10 40.5 0.0 5.9e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX23112.1 - 3.1e-08 33.8 0.0 8.7e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAX23112.1 - 0.11 13.3 0.0 0.33 11.7 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain RT_RNaseH_2 PF17919.1 GAX23113.1 - 1e-30 105.7 0.1 3.4e-30 104.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAX23113.1 - 5.1e-29 100.6 0.1 1.3e-28 99.3 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GAX23113.1 - 7.3e-16 58.4 0.0 2.3e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GAX23113.1 - 1.1e-15 57.4 2.1 3.4e-15 55.9 2.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GAX23113.1 - 2.9e-15 56.4 0.0 5.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GAX23113.1 - 0.017 15.3 0.8 0.058 13.6 0.1 2.4 2 0 0 2 2 2 0 H2C2 zinc finger Phage_G PF02306.15 GAX23114.1 - 0.099 12.4 0.5 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 Major spike protein (G protein) CRAL_TRIO PF00650.20 GAX23115.1 - 5.7e-29 100.9 0.0 9e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAX23115.1 - 0.0051 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAX23115.1 - 0.026 14.7 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Cnn_1N PF07989.11 GAX23116.1 - 0.3 11.3 13.7 0.082 13.1 4.1 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 GAX23116.1 - 0.57 10.4 16.3 1 9.6 16.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 GAX23116.1 - 0.74 9.1 13.9 0.92 8.8 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2730 PF10805.8 GAX23116.1 - 0.76 9.9 7.4 1.6 8.8 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) FapA PF03961.13 GAX23116.1 - 1.4 7.4 8.1 1.5 7.3 8.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A IL2 PF00715.17 GAX23116.1 - 1.4 8.8 6.4 2.4 8.1 6.4 1.4 1 1 0 1 1 1 0 Interleukin 2 CaM-KIIN PF15170.6 GAX23116.1 - 1.8 8.7 5.2 0.98 9.6 0.3 2.5 1 1 2 3 3 3 0 Calcium/calmodulin-dependent protein kinase II inhibitor V_ATPase_I PF01496.19 GAX23116.1 - 2 6.2 9.4 2.2 6.1 9.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 GAX23116.1 - 4.3 7.2 18.9 0.24 11.2 4.8 2.3 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.12 GAX23116.1 - 5.1 7.5 15.5 17 5.9 15.5 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Spc24 PF08286.11 GAX23116.1 - 6.3 7.1 13.8 3.6 7.9 2.8 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FUSC PF04632.12 GAX23116.1 - 7.4 5.0 5.5 8.9 4.7 5.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cyt-b5 PF00173.28 GAX23117.1 - 1.4e-08 34.7 0.0 2.2e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyclin_N PF00134.23 GAX23118.1 - 3.5e-14 52.6 0.2 5e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4611 PF15387.6 GAX23120.1 - 3 8.1 7.3 0.9 9.8 3.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Mod_r PF07200.13 GAX23121.1 - 4.6e-25 88.4 10.8 8.6e-25 87.6 10.8 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 GAX23121.1 - 0.011 16.1 1.7 0.011 16.1 1.7 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain Mce4_CUP1 PF11887.8 GAX23121.1 - 0.11 12.0 0.3 0.23 10.9 0.3 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Sec34 PF04136.15 GAX23121.1 - 0.11 12.4 3.0 0.19 11.6 3.0 1.4 1 0 0 1 1 1 0 Sec34-like family Seryl_tRNA_N PF02403.22 GAX23121.1 - 0.46 10.7 3.3 0.95 9.7 3.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain STN1_2 PF09170.10 GAX23121.1 - 1 9.6 5.5 0.5 10.5 2.5 2.0 1 1 1 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 CENP-H PF05837.12 GAX23121.1 - 1.2 9.6 5.4 1.2 9.6 3.6 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CBM_6 PF03422.15 GAX23122.1 - 8.3e-26 90.7 0.1 1.1e-13 51.6 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) CBM_35 PF16990.5 GAX23122.1 - 1e-08 35.4 0.2 0.0002 21.6 0.1 2.2 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) DUF5010_C PF18099.1 GAX23122.1 - 3.5e-08 33.5 0.0 1.1e-05 25.6 0.0 2.4 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_6 PF03422.15 GAX23123.1 - 3.9e-22 78.9 0.1 3.5e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX23123.1 - 4e-05 23.7 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX23123.1 - 5.4e-05 23.4 0.2 0.12 12.6 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) PT PF04886.12 GAX23123.1 - 0.34 10.5 28.2 0.44 10.1 7.3 2.8 1 1 1 2 2 2 0 PT repeat DEAD PF00270.29 GAX23124.1 - 5.6e-29 101.1 0.1 1.5e-28 99.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX23124.1 - 3.3e-16 59.6 0.0 1.2e-15 57.8 0.0 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX23124.1 - 3e-06 27.3 0.0 6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 GAX23124.1 - 0.17 11.2 0.0 9.4 5.4 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain CBM_6 PF03422.15 GAX23125.1 - 5.3e-06 26.7 0.2 1.4e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Carb_anhydrase PF00194.21 GAX23126.1 - 6.1e-15 55.4 1.6 4.9e-06 26.3 0.0 3.4 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase DUF4744 PF15918.5 GAX23126.1 - 0.081 13.8 0.1 1.8 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) Arrestin_C PF02752.22 GAX23127.1 - 5.3e-10 39.9 0.1 3.3e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAX23127.1 - 2.6e-07 30.8 0.2 5e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAX23127.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Aminotran_5 PF00266.19 GAX23130.1 - 2.1e-88 296.8 0.0 2.7e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAX23130.1 - 3.1e-09 36.5 0.0 4.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAX23130.1 - 2e-05 24.1 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAX23130.1 - 0.0028 16.2 0.0 0.0048 15.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CTP_transf_like PF01467.26 GAX23131.1 - 5.9e-06 26.5 0.0 3e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Cytidylyltransferase-like CinA PF02464.17 GAX23131.1 - 0.0051 16.4 0.2 0.0092 15.6 0.2 1.3 1 0 0 1 1 1 1 Competence-damaged protein PLAC8 PF04749.17 GAX23133.1 - 5.8e-14 52.9 6.5 1.2e-13 51.9 6.5 1.5 1 1 0 1 1 1 1 PLAC8 family Renin_r PF07850.14 GAX23133.1 - 0.2 12.3 0.1 0.35 11.5 0.1 1.3 1 0 0 1 1 1 0 Renin receptor-like protein WD40 PF00400.32 GAX23134.1 - 2.2e-19 69.4 14.8 0.00014 22.6 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX23134.1 - 9.2e-14 51.5 0.5 0.00025 21.3 0.2 4.6 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX23134.1 - 1.8e-05 24.7 0.0 0.59 10.0 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAX23134.1 - 0.0092 15.0 0.0 0.074 12.0 0.0 2.1 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA PF00004.29 GAX23135.1 - 6.2e-16 59.0 0.0 9.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 GAX23135.1 - 6.7e-13 48.9 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAX23135.1 - 1.8e-11 44.1 0.0 2e-09 37.4 0.0 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 GAX23135.1 - 2.3e-07 30.9 0.0 4.9e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 GAX23135.1 - 1.1e-05 25.2 0.0 2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX23135.1 - 2e-05 24.9 0.7 0.26 11.6 0.1 2.7 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.6 GAX23135.1 - 4.3e-05 24.0 0.0 9.8e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAX23135.1 - 6.6e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 GAX23135.1 - 9.1e-05 22.7 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 GAX23135.1 - 0.00015 21.7 0.1 0.0003 20.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GAX23135.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAX23135.1 - 0.00023 21.0 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX23135.1 - 0.00029 21.4 0.0 0.028 15.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX23135.1 - 0.00057 19.7 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAX23135.1 - 0.00071 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GAX23135.1 - 0.00074 19.3 0.3 0.011 15.5 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GAX23135.1 - 0.00091 19.6 0.7 0.02 15.2 0.2 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GAX23135.1 - 0.0042 16.3 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 GAX23135.1 - 0.0062 16.6 0.0 0.64 10.0 0.0 2.2 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 GAX23135.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 GAX23135.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit MCM PF00493.23 GAX23135.1 - 0.034 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain TIP49 PF06068.13 GAX23135.1 - 0.063 12.5 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 GAX23135.1 - 0.063 13.2 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 GAX23135.1 - 0.11 11.9 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 GAX23135.1 - 0.12 11.7 0.2 0.42 10.0 0.1 1.7 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 GAX23135.1 - 0.14 11.5 0.0 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 GAX23135.1 - 0.16 11.7 0.2 0.34 10.7 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vps51 PF08700.11 GAX23137.1 - 4.2e-18 65.2 0.4 1.6e-17 63.3 0.4 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 GAX23137.1 - 1.5e-08 33.7 4.8 3.1e-08 32.7 4.8 1.5 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 GAX23137.1 - 4.2e-07 30.0 0.0 1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.11 GAX23137.1 - 8.4e-05 22.7 0.3 0.00028 21.0 0.3 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 GAX23137.1 - 0.00024 20.5 1.2 0.00064 19.1 1.2 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 GAX23137.1 - 0.00095 19.3 1.2 0.00095 19.3 1.2 3.0 3 0 0 3 3 3 1 Golgi transport complex subunit 5 PAF PF15715.5 GAX23137.1 - 0.0021 18.6 0.1 0.0045 17.6 0.1 1.5 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TetR_C_36 PF18598.1 GAX23137.1 - 0.01 15.8 0.3 0.035 14.1 0.3 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SDA1 PF05285.12 GAX23137.1 - 1.8 7.9 7.3 3.2 7.1 7.3 1.4 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 GAX23137.1 - 5.2 6.3 17.8 9 5.5 17.8 1.4 1 0 0 1 1 1 0 NOA36 protein Cas1_AcylT PF07779.12 GAX23138.1 - 1.2e-82 278.4 31.3 1.6e-82 277.9 31.3 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 GAX23138.1 - 8.5e-05 22.4 4.1 0.00025 20.9 0.0 3.1 2 1 1 3 3 3 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL_2 PF13472.6 GAX23138.1 - 0.019 15.4 0.1 0.034 14.5 0.1 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PriCT_2 PF08707.11 GAX23138.1 - 0.079 13.3 5.5 0.67 10.4 0.1 3.0 3 0 0 3 3 3 0 Primase C terminal 2 (PriCT-2) DUF3446 PF11928.8 GAX23138.1 - 0.45 10.9 11.1 2.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Phage_holin_2_3 PF16080.5 GAX23138.1 - 4.7 7.1 6.1 45 3.9 1.9 3.1 2 0 0 2 2 2 0 Bacteriophage holin family HP1 SBP_bac_5 PF00496.22 GAX23139.1 - 2.8e-43 148.3 0.0 4.6e-37 127.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle Carb_anhydrase PF00194.21 GAX23140.1 - 1.1e-15 57.9 2.5 1.8e-07 31.0 0.0 3.3 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Imm5 PF14423.6 GAX23140.1 - 0.066 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 Carb_anhydrase PF00194.21 GAX23141.1 - 5.4e-17 62.2 2.1 1.1e-07 31.7 1.0 3.1 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase WD40 PF00400.32 GAX23142.1 - 7.7e-22 77.2 1.9 1.8e-06 28.5 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX23142.1 - 4.7e-11 42.8 0.1 0.00023 21.4 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 GAX23142.1 - 1.6e-06 27.7 1.0 2.4e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 GAX23142.1 - 4.1e-05 22.7 0.7 0.26 10.2 0.0 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAX23142.1 - 0.00013 20.8 0.0 1.5 7.3 0.0 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Hira PF07569.11 GAX23142.1 - 0.0016 18.2 0.4 0.057 13.1 0.0 3.1 3 1 1 4 4 4 1 TUP1-like enhancer of split PQQ_2 PF13360.6 GAX23142.1 - 0.0035 17.0 1.2 0.77 9.3 0.2 2.5 1 1 1 2 2 2 2 PQQ-like domain PALB2_WD40 PF16756.5 GAX23142.1 - 0.0048 15.9 0.3 0.64 8.9 0.0 3.0 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain LisH PF08513.11 GAX23142.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 LisH Cofac_haem_bdg PF04187.13 GAX23142.1 - 0.015 15.3 0.5 0.028 14.4 0.5 1.4 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Lipase_3 PF01764.25 GAX23143.1 - 9.9e-17 61.1 0.0 1.8e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) HSF_DNA-bind PF00447.17 GAX23144.1 - 9.6e-16 58.2 0.1 1.6e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Suf PF05843.14 GAX23145.1 - 6e-18 65.9 1.1 1.3e-13 51.7 0.0 3.5 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) Aminotran_1_2 PF00155.21 GAX23146.1 - 3.1e-57 194.4 0.0 3.6e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAX23146.1 - 2.7e-05 23.1 0.0 4.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 GAX23146.1 - 0.0007 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAX23146.1 - 0.00073 18.9 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Beta-eliminating lyase Alliinase_C PF04864.13 GAX23146.1 - 0.0036 16.2 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Allinase Aminotran_3 PF00202.21 GAX23146.1 - 0.0048 15.6 0.0 0.0072 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DinB_2 PF12867.7 GAX23146.1 - 0.025 15.1 0.6 0.18 12.3 0.1 2.4 3 0 0 3 3 3 0 DinB superfamily SCAN PF02023.17 GAX23146.1 - 0.11 12.4 0.7 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 SCAN domain DnaB_2 PF07261.11 GAX23146.1 - 0.16 11.8 0.0 23 4.8 0.0 2.8 3 0 0 3 3 3 0 Replication initiation and membrane attachment AMP-binding PF00501.28 GAX23147.1 - 3.6e-85 286.1 0.1 5.7e-85 285.5 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme zf-CXXC PF02008.20 GAX23149.1 - 6.9e-06 26.0 5.7 1.6e-05 24.8 5.7 1.6 1 0 0 1 1 1 1 CXXC zinc finger domain MFS_1 PF07690.16 GAX23150.1 - 2.8e-31 108.7 31.7 4.2e-31 108.2 31.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX23150.1 - 5.7e-11 42.0 3.3 5.7e-11 42.0 3.3 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAX23150.1 - 2.2e-05 23.5 24.9 0.0001 21.3 10.5 3.2 2 2 1 3 3 3 2 MFS_1 like family OATP PF03137.20 GAX23150.1 - 0.00087 17.7 10.5 0.038 12.3 10.7 2.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family IATP PF04568.12 GAX23151.1 - 0.00032 21.1 0.5 0.00043 20.6 0.5 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP EIIBC-GUT_N PF03612.14 GAX23151.1 - 0.0075 16.0 1.2 0.0083 15.9 1.2 1.1 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II N-terminus DUF501 PF04417.12 GAX23151.1 - 0.017 14.9 0.7 0.02 14.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF2730 PF10805.8 GAX23151.1 - 0.04 14.0 0.4 0.052 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) LRR_6 PF13516.6 GAX23151.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Leucine Rich repeat Pkinase PF00069.25 GAX23152.1 - 1.3e-64 218.1 0.0 2.4e-64 217.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23152.1 - 4.1e-28 98.4 0.2 1.4e-13 50.7 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX23152.1 - 0.0001 21.4 0.1 0.00019 20.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAX23152.1 - 0.045 13.1 0.1 0.045 13.1 0.1 2.1 3 0 0 3 3 3 0 Kinase-like AAA_18 PF13238.6 GAX23153.1 - 0.0039 17.7 0.0 0.013 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAX23153.1 - 0.065 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain HSF_DNA-bind PF00447.17 GAX23154.1 - 1.1e-17 64.4 0.3 1.8e-17 63.8 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Peptidase_M43 PF05572.13 GAX23157.1 - 2.9e-10 40.3 0.3 1.4e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX23157.1 - 0.0015 19.0 0.1 0.0051 17.3 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAX23157.1 - 0.0055 15.7 0.3 0.022 13.7 0.3 1.8 2 0 0 2 2 2 1 Peptidase M66 Peptidase_M7 PF02031.16 GAX23157.1 - 0.0092 16.1 0.2 0.54 10.4 0.1 2.4 2 0 0 2 2 2 1 Streptomyces extracellular neutral proteinase (M7) family DUF4953 PF16313.5 GAX23157.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 GAX23157.1 - 0.019 15.1 4.7 0.019 15.1 1.7 2.4 2 1 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX23157.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 GAX23157.1 - 0.07 11.7 0.7 0.12 11.0 0.7 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.24 GAX23157.1 - 0.2 11.5 0.4 0.45 10.3 0.4 1.5 1 0 0 1 1 1 0 Matrixin TauE PF01925.19 GAX23160.1 - 2.9e-16 59.8 26.6 7.4e-08 32.3 3.0 2.8 1 1 0 2 2 2 2 Sulfite exporter TauE/SafE FemAB PF02388.16 GAX23160.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 FemAB family LYRIC PF15686.5 GAX23160.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family FTCD_C PF04961.12 GAX23160.1 - 0.091 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Ytca PF17090.5 GAX23160.1 - 1.9 9.1 7.4 1 9.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family TauE PF01925.19 GAX23161.1 - 1.5e-20 73.9 9.6 4.3e-09 36.4 12.1 2.4 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE FA_hydroxylase PF04116.13 GAX23162.1 - 3.4e-18 66.3 19.5 3.4e-18 66.3 19.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Wax2_C PF12076.8 GAX23162.1 - 2.2e-05 24.3 0.0 0.0001 22.0 0.0 2.1 2 0 0 2 2 2 1 WAX2 C-terminal domain DAO PF01266.24 GAX23163.1 - 0.0098 15.5 0.4 2 7.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX23163.1 - 0.029 13.4 0.0 0.51 9.3 0.1 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein Guanylate_cyc PF00211.20 GAX23164.1 - 7.8e-48 162.5 0.0 1.6e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX23164.1 - 8.8e-32 110.7 0.2 2.6e-31 109.2 0.2 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SET PF00856.28 GAX23165.1 - 1.4e-06 28.8 0.0 0.0078 16.6 0.0 2.2 1 1 1 2 2 2 2 SET domain He_PIG_assoc PF10632.9 GAX23165.1 - 1.9 8.2 4.9 0.54 10.0 0.2 2.4 3 0 0 3 3 3 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase PFU PF09070.11 GAX23166.1 - 3.1e-26 91.8 0.1 7e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 GAX23166.1 - 5e-23 81.7 5.1 9.4e-23 80.8 5.1 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 GAX23166.1 - 5.5e-20 71.3 7.4 4.9e-09 36.7 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX23166.1 - 0.026 14.8 2.5 1.7 9.0 0.1 3.7 2 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain MyTH4 PF00784.17 GAX23166.1 - 0.071 13.6 0.1 0.6 10.6 0.0 2.5 2 0 0 2 2 2 0 MyTH4 domain Peptidase_M50 PF02163.22 GAX23167.1 - 2.1e-05 23.9 4.6 0.016 14.5 0.5 2.4 2 0 0 2 2 2 2 Peptidase family M50 SlyX PF04102.12 GAX23167.1 - 0.093 13.4 2.1 0.23 12.1 2.1 1.7 1 0 0 1 1 1 0 SlyX DUF1043 PF06295.12 GAX23167.1 - 7 6.7 7.4 1.9 8.5 4.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DnaG_DnaB_bind PF08278.11 GAX23168.1 - 0.11 13.1 3.3 0.08 13.5 0.9 2.0 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Mit_ribos_Mrp51 PF11709.8 GAX23168.1 - 0.19 11.3 1.7 0.28 10.7 1.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Peptidase_M50 PF02163.22 GAX23168.1 - 4.2 6.6 6.0 12 5.0 0.1 3.1 2 1 0 3 3 3 0 Peptidase family M50 PI-PLC-X PF00388.19 GAX23169.1 - 4.7e-21 74.9 0.0 2.7e-20 72.5 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAX23169.1 - 5.4e-19 68.6 0.0 7.3e-18 65.0 0.0 2.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 GAX23169.1 - 0.0084 16.6 1.7 0.027 14.9 0.0 3.0 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 GAX23169.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.8 1 0 0 1 1 1 0 C2 domain zf-C3HC PF07967.13 GAX23169.1 - 0.24 11.4 2.6 2.7 8.0 1.3 2.9 2 0 0 2 2 2 0 C3HC zinc finger-like p450 PF00067.22 GAX23170.1 - 2.4e-80 270.5 0.0 5.3e-80 269.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 PQQ_3 PF13570.6 GAX23171.1 - 0.0094 16.4 6.0 15 6.2 0.0 6.1 7 1 0 7 7 7 1 PQQ-like domain Ge1_WD40 PF16529.5 GAX23171.1 - 0.12 11.3 0.0 0.87 8.5 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 GAX23171.1 - 1.2 10.1 12.2 11 7.1 0.2 6.8 9 0 0 9 9 9 0 WD domain, G-beta repeat DNA_topoisoIV PF00521.20 GAX23176.1 - 2.1e-138 461.8 0.0 2.6e-138 461.5 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 GAX23176.1 - 1e-57 191.4 6.7 1.1e-12 47.2 0.1 6.4 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Borrelia_REV PF03978.13 GAX23176.1 - 0.0088 16.0 1.4 0.02 14.8 1.4 1.5 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein KHA PF11834.8 GAX23176.1 - 0.021 14.9 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel AAA PF00004.29 GAX23177.1 - 1.1e-30 106.7 0.0 3.8e-30 105.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX23177.1 - 3.6e-08 33.1 0.2 9.1e-08 31.8 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 GAX23177.1 - 2.5e-05 23.8 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX23177.1 - 4.6e-05 23.4 0.0 0.00017 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 GAX23177.1 - 0.00015 21.2 0.0 0.0018 17.7 0.0 2.1 1 1 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 GAX23177.1 - 0.00018 21.8 0.1 0.0022 18.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAX23177.1 - 0.00047 19.5 0.0 0.023 13.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 GAX23177.1 - 0.00075 19.9 0.3 0.0032 17.9 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 GAX23177.1 - 0.00093 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAX23177.1 - 0.0012 19.3 0.0 0.004 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 GAX23177.1 - 0.0065 15.3 0.0 0.028 13.2 0.0 1.8 2 0 0 2 2 2 1 Adenovirus IVa2 protein RNA_helicase PF00910.22 GAX23177.1 - 0.008 16.6 0.1 0.024 15.0 0.0 2.0 2 1 0 2 2 1 1 RNA helicase Rad17 PF03215.15 GAX23177.1 - 0.0099 15.8 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 GAX23177.1 - 0.011 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX23177.1 - 0.013 15.7 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX23177.1 - 0.029 14.9 0.0 0.093 13.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 GAX23177.1 - 0.049 13.9 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX23177.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAX23177.1 - 0.12 12.0 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAX23177.1 - 0.13 12.6 0.1 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAX23177.1 - 0.15 12.0 0.0 0.8 9.6 0.0 2.2 1 1 0 1 1 1 0 NACHT domain RRM_1 PF00076.22 GAX23178.1 - 1.9e-18 66.0 0.1 6.1e-08 32.4 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX23178.1 - 6.9e-08 32.5 0.0 0.0032 17.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif HMG_box PF00505.19 GAX23179.1 - 8.3e-37 125.4 8.0 1.3e-22 80.0 1.5 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX23179.1 - 3.5e-21 75.6 10.3 5.7e-11 42.8 1.0 2.7 2 1 1 3 3 3 2 HMG-box domain Carbpep_Y_N PF05388.11 GAX23179.1 - 0.054 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide PH_4 PF15404.6 GAX23179.1 - 0.084 12.7 0.4 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain MlaC PF05494.12 GAX23179.1 - 0.15 11.8 0.6 4.4 7.0 0.0 2.6 2 1 0 2 2 2 0 MlaC protein EssA PF10661.9 GAX23179.1 - 0.56 10.0 3.5 1.2 9.0 3.5 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Beta_helix PF13229.6 GAX23180.1 - 2.7e-06 27.3 4.6 6.1e-05 22.9 0.7 2.2 2 0 0 2 2 2 2 Right handed beta helix region DUF5123 PF17161.4 GAX23180.1 - 2.3e-05 25.4 2.7 0.0025 18.9 0.5 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF5123) Pentapeptide_3 PF13576.6 GAX23180.1 - 0.006 16.7 4.1 4 7.7 0.4 4.1 3 1 0 3 3 3 2 Pentapeptide repeats (9 copies) MFS_1 PF07690.16 GAX23181.1 - 3.1e-50 171.1 5.1 3.1e-50 171.1 5.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX23181.1 - 1.3e-19 70.4 2.2 4e-19 68.8 1.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 GAX23181.1 - 8.7e-06 25.3 7.2 0.00014 21.3 0.1 3.0 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 GAX23181.1 - 2.9e-05 22.8 15.0 0.012 14.2 5.6 3.1 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 GAX23181.1 - 0.0001 20.7 0.0 0.0086 14.4 0.0 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 GAX23181.1 - 0.027 13.3 4.4 0.28 10.0 0.3 2.8 2 1 2 4 4 4 0 MFS_1 like family Folate_carrier PF01770.18 GAX23181.1 - 0.048 12.4 0.0 0.36 9.5 0.0 2.0 2 0 0 2 2 2 0 Reduced folate carrier ThrE PF06738.12 GAX23181.1 - 2.1 7.7 4.9 0.35 10.2 0.3 2.0 2 0 0 2 2 2 0 Putative threonine/serine exporter WD40 PF00400.32 GAX23183.1 - 5.9e-31 106.0 17.5 9.4e-07 29.5 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX23183.1 - 4.1e-08 33.4 1.5 1 9.7 0.0 5.5 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Exostosin PF03016.15 GAX23184.1 - 0.061 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Exostosin family DUF3198 PF11433.8 GAX23184.1 - 0.096 12.6 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) RVT_2 PF07727.14 GAX23185.1 - 6.7e-21 75.0 0.0 1.2e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF616 PF04765.13 GAX23186.1 - 4e-08 32.9 0.1 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF616) PSI_PsaE PF02427.17 GAX23186.1 - 0.12 12.0 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE Thioredoxin PF00085.20 GAX23187.1 - 9.4e-15 54.5 0.5 2.1e-14 53.3 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin Evr1_Alr PF04777.13 GAX23187.1 - 5e-14 52.6 0.8 5e-14 52.6 0.8 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin_2 PF13098.6 GAX23187.1 - 0.0018 18.7 0.1 0.0051 17.2 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAX23187.1 - 0.024 14.9 0.0 0.086 13.2 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like Zn_Tnp_IS1595 PF12760.7 GAX23187.1 - 0.16 12.0 4.9 6.2 6.9 0.3 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Ribosomal_S5_C PF03719.15 GAX23188.1 - 4.6e-19 67.7 0.0 8.3e-19 66.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 GAX23188.1 - 3.2e-17 62.2 0.0 5.9e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Maf PF02545.14 GAX23189.1 - 8.5e-56 188.4 0.0 1e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein NUC205 PF08168.11 GAX23189.1 - 0.019 14.5 0.0 0.06 12.9 0.0 1.9 1 0 0 1 1 1 0 NUC205 domain Alpha_kinase PF02816.18 GAX23190.1 - 6.8e-33 114.3 0.5 1.3e-17 64.5 0.3 2.3 2 0 0 2 2 2 2 Alpha-kinase family VWA_2 PF13519.6 GAX23190.1 - 0.00013 22.5 0.0 0.0004 21.0 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF4258 PF14076.6 GAX23190.1 - 0.04 14.3 3.0 0.057 13.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4258) WD40 PF00400.32 GAX23191.1 - 0.057 14.3 9.9 27 5.8 0.4 5.3 5 0 0 5 5 5 0 WD domain, G-beta repeat Bestrophin PF01062.21 GAX23193.1 - 2.8e-11 43.4 0.3 2.8e-11 43.4 0.3 1.5 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel ATP-synt_E PF05680.12 GAX23193.1 - 7.7 6.9 9.1 27 5.2 9.1 2.0 1 0 0 1 1 1 0 ATP synthase E chain CoaE PF01121.20 GAX23194.1 - 1.2e-33 116.3 0.1 1.7e-32 112.5 0.1 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase Herpes_Helicase PF02689.14 GAX23194.1 - 0.0082 14.1 0.0 0.011 13.7 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_18 PF13238.6 GAX23194.1 - 0.011 16.3 0.1 0.092 13.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAX23194.1 - 0.016 15.7 0.1 4.1 7.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX23194.1 - 0.032 14.5 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAX23194.1 - 0.086 13.0 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAX23194.1 - 0.093 12.0 0.1 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 GAX23194.1 - 0.13 11.9 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family eRF1_1 PF03463.15 GAX23195.1 - 1.5e-45 154.3 0.4 4.3e-45 152.9 0.1 1.9 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 GAX23195.1 - 7.4e-29 100.7 0.4 1.3e-28 100.0 0.4 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAX23195.1 - 1.6e-24 86.6 0.0 3.5e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 A_deamin PF02137.18 GAX23196.1 - 1.7e-48 165.8 4.7 2.1e-47 162.2 4.7 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain SWIB PF02201.18 GAX23199.1 - 1.2e-54 182.1 0.2 7.7e-27 93.0 0.1 2.3 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 GAX23199.1 - 5.2e-07 29.5 1.7 3.5e-05 23.6 0.2 3.5 4 0 0 4 4 4 1 DEK C terminal domain SNF2_N PF00176.23 GAX23200.1 - 1.1e-26 93.5 0.1 6.2e-26 90.9 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 GAX23200.1 - 1.9e-17 63.6 0.9 2.6e-16 59.9 0.0 2.5 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 GAX23200.1 - 0.00037 20.8 0.0 0.0009 19.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Shugoshin_C PF07557.11 GAX23200.1 - 0.071 12.9 1.2 0.19 11.6 1.2 1.8 1 0 0 1 1 1 0 Shugoshin C terminus zf-RING_5 PF14634.6 GAX23200.1 - 0.65 10.0 13.8 3.2 7.8 13.8 2.3 1 0 0 1 1 1 0 zinc-RING finger domain AA_kinase PF00696.28 GAX23201.1 - 6.3e-38 130.7 0.1 7.7e-38 130.5 0.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family UDG PF03167.19 GAX23202.1 - 1.1e-22 80.7 0.0 1.6e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily START PF01852.19 GAX23204.1 - 0.0014 18.1 0.0 0.0049 16.3 0.0 1.8 1 1 0 1 1 1 1 START domain TauE PF01925.19 GAX23205.1 - 2.1e-23 83.2 33.4 3.2e-13 49.9 6.3 2.9 2 1 0 3 3 3 2 Sulfite exporter TauE/SafE PBP1_TM PF14812.6 GAX23205.1 - 0.0039 17.5 1.6 0.0039 17.5 1.6 3.4 2 1 1 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 GAX23205.1 - 0.31 9.9 28.9 0.19 10.6 0.1 3.1 2 1 0 2 2 2 0 Major Facilitator Superfamily Wzy_C_2 PF11846.8 GAX23205.1 - 2.2 8.2 5.6 11 5.9 0.3 3.3 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Sid-5 PF17204.3 GAX23205.1 - 4 7.7 5.3 12 6.2 0.5 3.4 3 0 0 3 3 3 0 Sid-5 family Ac76 PF05814.11 GAX23205.1 - 5.8 7.0 9.1 2.2 8.4 0.2 3.1 3 1 1 4 4 4 0 Orf76 (Ac76) zf-CCHC PF00098.23 GAX23206.1 - 4e-08 33.0 1.9 6.6e-08 32.3 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle cwf21 PF08312.12 GAX23206.1 - 0.00013 22.0 9.6 0.00013 22.0 9.6 2.2 2 0 0 2 2 2 1 cwf21 domain zf-CCHC_3 PF13917.6 GAX23206.1 - 0.0077 16.2 0.1 0.0077 16.2 0.1 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GAX23206.1 - 0.1 12.5 1.9 0.17 11.8 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Adap_comp_sub PF00928.21 GAX23207.1 - 2.3e-86 289.5 0.2 3e-86 289.1 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAX23207.1 - 2.7e-05 24.1 0.2 5.5e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 GAX23207.1 - 0.0021 17.6 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DHHC PF01529.20 GAX23208.1 - 8.4e-35 119.8 6.3 8.4e-35 119.8 6.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Multi_Drug_Res PF00893.19 GAX23208.1 - 1.7 9.3 5.5 0.24 12.1 0.5 2.1 2 1 0 2 2 2 0 Small Multidrug Resistance protein DUF2183 PF09949.9 GAX23209.1 - 0.044 14.1 0.0 0.18 12.2 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) MORN PF02493.20 GAX23210.1 - 2.2e-24 83.9 33.4 5.7e-06 25.9 2.0 7.3 7 0 0 7 7 7 7 MORN repeat zf-NADH-PPase PF09297.11 GAX23210.1 - 0.021 14.5 0.3 0.057 13.1 0.3 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain MORN_2 PF07661.13 GAX23210.1 - 0.53 10.7 10.5 8.7 6.9 0.1 4.2 4 0 0 4 4 4 0 MORN repeat variant DUF4085 PF13315.6 GAX23211.1 - 0.011 15.4 0.2 0.024 14.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) PP2C PF00481.21 GAX23212.1 - 4.3e-36 124.9 0.0 5.7e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX23212.1 - 1.6e-07 31.2 0.1 1.7e-05 24.6 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 GAX23212.1 - 4.4e-05 23.5 0.2 0.00065 19.7 0.2 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) SWIRM PF04433.17 GAX23213.1 - 1.1e-14 54.5 0.0 2.8e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAX23213.1 - 8.9e-11 41.6 2.5 2.2e-10 40.3 2.5 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 MCCD1 PF15707.5 GAX23213.1 - 0.047 14.1 1.7 0.11 12.9 1.7 1.7 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 Ras PF00071.22 GAX23214.1 - 4.6e-59 198.6 0.0 5.2e-59 198.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX23214.1 - 2.6e-33 114.8 0.0 4e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX23214.1 - 3.8e-14 52.5 0.0 4.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX23214.1 - 0.0026 17.8 0.0 0.0044 17.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX23214.1 - 0.032 14.1 0.0 7.5 6.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 GAX23214.1 - 0.051 12.9 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 GAX23214.1 - 0.15 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF3079 PF11278.8 GAX23214.1 - 3.8 7.4 7.0 4.5 7.2 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3079) NOC3p PF07540.11 GAX23215.1 - 8.7e-24 83.8 1.9 1.3e-23 83.3 0.1 2.2 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 GAX23215.1 - 3.3e-19 69.5 0.1 3.3e-19 69.5 0.1 2.6 2 1 0 2 2 2 1 CBF/Mak21 family zf-RING_4 PF14570.6 GAX23216.1 - 2.5e-21 75.2 14.3 3.8e-21 74.6 14.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GAX23216.1 - 3.5e-06 26.8 10.4 6e-06 26.0 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 GAX23216.1 - 3.7e-06 26.7 0.0 9.1e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.6 GAX23216.1 - 0.012 15.7 4.2 0.025 14.7 4.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 GAX23216.1 - 1.8 8.5 6.1 3.5 7.6 6.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE_2 PF02318.16 GAX23216.1 - 3.5 7.9 7.1 6.7 7.0 7.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Acetyltransf_1 PF00583.25 GAX23217.1 - 6.6e-13 48.9 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX23217.1 - 4.4e-11 42.8 0.1 8.9e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX23217.1 - 1.2e-09 38.4 0.1 2.2e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX23217.1 - 3.6e-05 23.9 0.0 6.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAX23217.1 - 0.00024 21.3 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX23217.1 - 0.00063 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAX23217.1 - 0.0031 17.6 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 GAX23217.1 - 0.021 15.5 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATG22 PF11700.8 GAX23218.1 - 1.6e-15 56.7 25.8 3.9e-12 45.6 16.0 2.2 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAX23218.1 - 1.2e-10 40.8 28.3 1.2e-10 40.8 28.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily PGM_PMM_I PF02878.16 GAX23219.1 - 6.4e-30 103.7 0.0 9.3e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAX23219.1 - 2e-23 82.7 0.0 7.3e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAX23219.1 - 1e-10 42.1 0.0 3.4e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ShK PF01549.24 GAX23221.1 - 1.4e-05 25.5 4.3 1.4e-05 25.5 4.3 1.8 2 0 0 2 2 2 1 ShK domain-like Sushi_2 PF09014.10 GAX23221.1 - 0.11 12.4 0.8 0.68 9.9 0.4 2.1 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Hydrolase_3 PF08282.12 GAX23222.1 - 0.031 14.0 0.0 3.2 7.4 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase WW PF00397.26 GAX23223.1 - 7.2e-13 48.4 2.0 2.1e-12 46.9 2.0 1.9 1 0 0 1 1 1 1 WW domain Cyclin_N PF00134.23 GAX23224.1 - 2.3e-07 30.6 0.0 4.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX23224.1 - 0.018 15.1 0.8 0.048 13.7 0.8 1.9 1 1 0 1 1 1 0 Cyclin, C-terminal domain PAS_9 PF13426.7 GAX23225.1 - 3e-09 37.1 0.0 6.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 GAX23225.1 - 6.5e-08 32.6 0.0 1.3e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 GAX23225.1 - 0.00069 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 GAX23225.1 - 0.019 15.0 0.0 0.17 11.9 0.0 2.2 1 1 1 2 2 2 0 PAS domain PAS_3 PF08447.12 GAX23225.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF577 PF04510.12 GAX23225.1 - 0.23 11.4 0.2 0.56 10.1 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF577) Rhomboid PF01694.22 GAX23226.1 - 1.6e-17 63.9 14.4 3.2e-17 62.9 14.4 1.5 1 1 0 1 1 1 1 Rhomboid family DUF543 PF04418.12 GAX23226.1 - 0.011 15.7 0.3 0.6 10.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Peptidase_U4 PF03419.13 GAX23226.1 - 6 6.1 6.1 5.1 6.3 4.5 1.7 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Porphyrn_cat_1 PF18206.1 GAX23227.1 - 0.051 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Porphyranase catalytic subdomain 1 zf-MYND PF01753.18 GAX23228.1 - 5.7e-08 32.7 14.2 1e-07 31.9 14.2 1.4 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.28 GAX23228.1 - 2.5e-06 27.0 0.2 0.0025 17.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX23228.1 - 1.2e-05 25.7 0.9 9.4e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23228.1 - 0.00024 21.3 0.9 0.066 13.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23228.1 - 0.00042 20.1 0.1 0.72 10.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX23228.1 - 0.0016 18.4 2.4 0.097 12.8 0.0 3.9 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23228.1 - 0.0027 17.8 0.5 0.46 10.8 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX23228.1 - 0.0064 17.1 1.3 5.8 7.7 0.4 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX23228.1 - 0.0092 15.8 0.1 2 8.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX23228.1 - 0.017 15.4 1.3 75 4.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX23228.1 - 0.018 15.8 0.2 31 5.7 0.0 4.0 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23228.1 - 0.063 13.9 0.1 1.1 10.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ST7 PF04184.12 GAX23228.1 - 0.13 10.7 0.0 0.31 9.5 0.0 1.6 1 1 0 1 1 1 0 ST7 protein Spt4 PF06093.13 GAX23229.1 - 2.4e-28 98.1 0.1 3.1e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger PC-Esterase PF13839.6 GAX23230.1 - 0.049 13.4 0.3 0.13 12.0 0.2 1.8 1 1 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF3875 PF12991.7 GAX23230.1 - 0.12 12.4 0.0 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3875) Trp_Tyr_perm PF03222.13 GAX23231.1 - 8.7e-70 235.7 25.7 1.4e-69 235.0 25.7 1.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 GAX23231.1 - 7.3e-06 24.9 23.5 7.5e-05 21.6 23.5 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PseudoU_synth_2 PF00849.22 GAX23232.1 - 2.1e-25 89.7 0.0 7.7e-25 87.8 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_M20 PF01546.28 GAX23233.1 - 1.2e-33 116.6 0.0 1.8e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAX23233.1 - 1.4e-07 31.4 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAX23233.1 - 2.9e-05 23.9 0.0 0.00014 21.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Methyltransf_16 PF10294.9 GAX23236.1 - 7e-28 97.5 0.1 8.5e-28 97.2 0.1 1.0 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX23236.1 - 5.9e-06 25.9 0.0 7.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX23236.1 - 6.7e-05 23.5 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX23236.1 - 7.2e-05 22.6 0.0 9.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX23236.1 - 0.00064 19.6 0.0 0.00081 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 GAX23236.1 - 0.0014 17.7 0.0 0.0018 17.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.13 GAX23236.1 - 0.0066 15.9 0.0 0.0071 15.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAX23236.1 - 0.085 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 GAX23236.1 - 0.15 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Spermine/spermidine synthase domain GvpL_GvpF PF06386.11 GAX23237.1 - 0.26 11.2 1.9 0.37 10.7 1.9 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Metallophos PF00149.28 GAX23238.1 - 2e-10 41.5 0.1 3.9e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX23238.1 - 1.2e-06 28.8 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 GAX23238.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily MTS PF05175.14 GAX23239.1 - 4.4e-05 23.1 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX23239.1 - 0.00014 22.5 0.0 0.0004 21.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 GAX23239.1 - 0.00056 19.1 0.0 0.0011 18.2 0.0 1.4 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 GAX23239.1 - 0.0015 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GAX23239.1 - 0.0064 16.2 0.0 0.03 14.0 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 GAX23239.1 - 0.035 14.8 0.0 0.094 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX23239.1 - 0.069 13.9 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Guanylate_cyc PF00211.20 GAX23240.1 - 2e-15 56.9 0.2 1.4e-07 31.3 0.0 2.8 3 1 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 GAX23240.1 - 1.3e-12 48.4 0.2 2.4e-07 31.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAX23240.1 - 0.00027 21.2 0.0 0.0011 19.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAX23240.1 - 0.0021 17.3 0.6 0.017 14.3 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain NACHT PF05729.12 GAX23240.1 - 0.0026 17.7 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 GAX23240.1 - 0.0085 15.6 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein TPR_2 PF07719.17 GAX23240.1 - 0.027 14.6 0.0 0.34 11.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2075 PF09848.9 GAX23240.1 - 0.04 13.1 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 GAX23240.1 - 0.051 14.1 0.3 0.2 12.2 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 GAX23240.1 - 0.063 12.8 0.1 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region OKR_DC_1_N PF03709.15 GAX23240.1 - 0.064 13.5 0.1 1.4 9.2 0.0 3.0 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain TPR_12 PF13424.6 GAX23240.1 - 0.067 13.5 0.1 1.9 8.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_19 PF13245.6 GAX23240.1 - 0.11 12.8 0.0 3.9 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 GAX23240.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Presenilin PF01080.17 GAX23241.1 - 0.0034 16.2 6.6 0.0034 16.2 6.6 1.9 2 0 0 2 2 2 1 Presenilin DDHD PF02862.17 GAX23241.1 - 0.046 13.9 3.9 0.079 13.1 3.9 1.4 1 0 0 1 1 1 0 DDHD domain rRNA_processing PF08524.11 GAX23241.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 rRNA processing Tim54 PF11711.8 GAX23241.1 - 1.8 7.3 6.5 2.7 6.7 6.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 GAX23241.1 - 2.9 6.8 10.7 4.3 6.3 10.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 GAX23241.1 - 4.5 7.7 8.6 7.2 7.0 7.5 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 CDC45 PF02724.14 GAX23241.1 - 4.9 5.3 12.5 6.8 4.8 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Gti1_Pac2 PF09729.9 GAX23241.1 - 8.4 6.4 10.7 17 5.5 10.7 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Mitoc_mL59 PF18126.1 GAX23242.1 - 1.9e-07 31.4 5.7 2.9e-06 27.6 5.7 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Ni_hydr_CYTB PF01292.20 GAX23243.1 - 1.3e-15 57.4 6.0 1.8e-15 57.0 6.0 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 AIRC PF00731.20 GAX23244.1 - 5.1e-65 217.6 2.8 5.1e-65 217.6 2.8 2.3 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 GAX23244.1 - 5.7e-45 153.0 0.0 1.1e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 GAX23244.1 - 1.3e-18 66.4 0.1 2.6e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Jag_N PF14804.6 GAX23244.1 - 0.025 14.9 1.1 0.42 11.0 0.2 2.8 2 0 0 2 2 2 0 Jag N-terminus Dala_Dala_lig_C PF07478.13 GAX23244.1 - 0.087 12.3 0.0 0.28 10.7 0.0 1.8 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus PhyH PF05721.13 GAX23245.1 - 1.1e-25 91.2 0.9 2.1e-25 90.2 0.9 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Thioredoxin PF00085.20 GAX23246.1 - 4.6e-14 52.2 0.1 1.4e-13 50.7 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 GAX23246.1 - 2e-13 50.6 0.5 4.9e-13 49.4 0.5 1.7 1 0 0 1 1 1 1 Erv1 / Alr family DUF3343 PF11823.8 GAX23246.1 - 0.042 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Thioredoxin_8 PF13905.6 GAX23246.1 - 0.19 12.0 0.6 1.5 9.2 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin-like Thioredoxin PF00085.20 GAX23247.1 - 1.8e-14 53.6 0.0 3.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 GAX23247.1 - 1.3e-11 44.8 2.0 8.5e-11 42.2 0.1 2.8 3 0 0 3 3 3 1 Erv1 / Alr family OST3_OST6 PF04756.13 GAX23247.1 - 0.00046 19.6 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAX23247.1 - 0.0013 19.1 0.0 0.0035 17.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX23247.1 - 0.0029 17.8 0.0 0.0077 16.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX23247.1 - 0.0038 17.5 0.0 0.026 14.8 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like TniQ PF06527.11 GAX23247.1 - 0.23 12.2 1.9 23 5.7 0.7 2.6 2 0 0 2 2 2 0 TniQ DUF35_N PF12172.8 GAX23247.1 - 1.2 9.0 5.1 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_Tnp_IS1595 PF12760.7 GAX23247.1 - 3.9 7.5 7.2 23 5.0 0.1 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Sdh5 PF03937.16 GAX23248.1 - 5.2e-21 74.4 1.2 1.4e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase zf-RING_2 PF13639.6 GAX23249.1 - 4.4e-11 42.9 5.7 8.3e-11 42.1 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX23249.1 - 1.9e-07 30.8 5.8 3.6e-07 29.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX23249.1 - 4.1e-07 29.9 3.9 6.8e-07 29.2 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAX23249.1 - 4.5e-07 30.1 4.0 1e-06 28.9 4.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX23249.1 - 4.7e-07 29.7 0.7 1e-06 28.7 0.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAX23249.1 - 5.3e-07 29.3 2.4 5.3e-07 29.3 2.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX23249.1 - 1.9e-06 27.6 5.8 3.6e-06 26.7 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX23249.1 - 4.2e-06 26.5 4.2 7.3e-06 25.8 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX23249.1 - 9.7e-06 25.4 4.2 1.9e-05 24.4 4.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX23249.1 - 0.00079 19.4 1.9 0.0021 18.1 1.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX23249.1 - 0.016 14.8 5.4 0.029 14.0 4.5 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAX23249.1 - 0.091 12.9 6.0 0.22 11.7 6.0 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 GAX23249.1 - 0.11 12.6 0.9 0.28 11.3 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 GAX23249.1 - 0.32 10.8 4.4 1.6 8.6 4.9 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SAGA-Tad1 PF12767.7 GAX23249.1 - 1.5 8.5 4.9 1.4 8.6 2.6 2.1 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit FANCL_C PF11793.8 GAX23249.1 - 1.9 8.7 9.5 0.36 11.0 5.2 2.1 2 1 0 2 2 1 0 FANCL C-terminal domain ER_lumen_recept PF00810.18 GAX23249.1 - 2.1 9.1 11.1 4.1 8.2 11.1 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor EamA PF00892.20 GAX23250.1 - 1.1e-20 74.2 34.1 7.1e-11 42.4 10.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family SPC12 PF06645.13 GAX23251.1 - 4e-29 100.5 2.2 4.4e-29 100.4 2.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Mntp PF02659.15 GAX23251.1 - 0.017 14.9 1.2 0.02 14.7 1.2 1.1 1 0 0 1 1 1 0 Putative manganese efflux pump DUF1453 PF07301.11 GAX23251.1 - 0.027 14.5 0.5 0.035 14.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) DUF3087 PF11286.8 GAX23251.1 - 0.11 12.0 0.1 0.12 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Methyltransf_15 PF09445.10 GAX23253.1 - 5e-25 88.0 0.0 1.1e-24 86.9 0.0 1.6 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 GAX23253.1 - 0.00018 22.2 0.0 0.00047 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 GAX23253.1 - 0.00099 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRM PF02005.16 GAX23253.1 - 0.0015 17.8 0.1 0.0023 17.2 0.1 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase AviRa PF11599.8 GAX23253.1 - 0.0057 16.1 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 GAX23253.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 GAX23253.1 - 0.063 13.0 0.2 3 7.5 0.1 2.8 3 1 0 3 3 3 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 GAX23253.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 GAX23253.1 - 0.079 13.6 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF21 PF01595.20 GAX23254.1 - 1e-39 136.0 3.8 2.2e-39 135.0 2.8 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAX23254.1 - 2.5e-12 47.0 1.8 5.4e-06 26.8 0.2 2.9 2 1 0 3 3 3 2 CBS domain cNMP_binding PF00027.29 GAX23254.1 - 0.0005 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2116 PF09889.9 GAX23254.1 - 0.31 11.0 3.1 0.35 10.9 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DEAD PF00270.29 GAX23255.1 - 4.1e-15 56.0 0.0 1.6e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX23255.1 - 1.6e-13 50.9 0.0 7.3e-12 45.6 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-GRF PF06839.12 GAX23255.1 - 5.4e-12 45.6 3.8 1.2e-11 44.5 3.8 1.7 1 0 0 1 1 1 1 GRF zinc finger SAP PF02037.27 GAX23255.1 - 1.3e-07 31.2 0.3 2.8e-07 30.2 0.3 1.6 1 0 0 1 1 1 1 SAP domain ResIII PF04851.15 GAX23255.1 - 3.7e-07 30.3 0.0 9.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FANC_SAP PF18081.1 GAX23255.1 - 0.066 13.4 1.2 0.19 11.9 0.3 2.3 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain DUF1805 PF08827.11 GAX23255.1 - 0.11 12.9 0.0 7.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) RCC1 PF00415.18 GAX23256.1 - 4.7e-31 107.2 7.1 9.9e-09 35.7 0.4 6.9 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX23256.1 - 6.8e-13 48.0 17.4 0.033 14.0 0.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.22 GAX23258.1 - 7.3e-16 57.8 0.0 1.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.6 GAX23258.1 - 0.0026 17.6 3.3 0.021 14.7 3.3 2.1 1 1 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 GAX23258.1 - 0.086 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Nop52 PF05997.12 GAX23259.1 - 4e-44 151.0 2.2 1.6e-26 93.5 0.4 3.0 3 0 0 3 3 3 2 Nucleolar protein,Nop52 SDA1 PF05285.12 GAX23259.1 - 0.1 12.0 55.8 0.041 13.3 14.5 2.4 2 0 0 2 2 2 0 SDA1 ketoacyl-synt PF00109.26 GAX23260.1 - 1.4e-45 155.9 1.8 1.4e-45 155.9 1.8 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAX23260.1 - 2e-29 102.0 0.1 4.3e-29 100.9 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAX23260.1 - 0.0033 16.8 0.3 0.0063 15.9 0.3 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RRM_1 PF00076.22 GAX23262.1 - 1.7e-10 40.6 0.0 9.3e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Golgin_A5 PF09787.9 GAX23263.1 - 2.2e-10 40.5 14.5 2.2e-10 40.5 14.5 3.7 2 1 2 4 4 4 1 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 GAX23263.1 - 0.0039 17.2 27.6 0.0039 17.2 27.6 6.5 1 1 2 5 5 5 3 TPR/MLP1/MLP2-like protein Sas6_CC PF18594.1 GAX23263.1 - 0.11 12.3 6.0 11 5.9 0.1 3.5 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Spc7 PF08317.11 GAX23263.1 - 1.7 7.4 85.6 3.2 6.5 25.7 3.6 1 1 2 3 3 3 0 Spc7 kinetochore protein TPM_phosphatase PF04536.14 GAX23264.1 - 2.7e-10 40.5 0.0 3.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 TPM domain Glyco_trans_4_4 PF13579.6 GAX23264.1 - 0.094 13.2 0.0 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain BamHI PF02923.15 GAX23265.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease BamHI RNA_pol_N PF01194.17 GAX23266.1 - 2.4e-33 114.2 0.3 2.8e-33 114.0 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 GAX23266.1 - 0.037 14.3 0.5 0.068 13.4 0.5 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Arc_C PF18162.1 GAX23267.1 - 0.19 11.6 2.0 0.45 10.4 0.4 2.3 1 1 2 3 3 3 0 Arc C-lobe WDCP PF15390.6 GAX23267.1 - 0.25 9.7 6.5 0.31 9.4 6.5 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SAE2 PF08573.10 GAX23267.1 - 6.9 7.8 7.6 9.4 7.4 6.7 1.8 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus FUSC PF04632.12 GAX23267.1 - 7.7 4.9 7.3 9.2 4.7 7.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Kelch_4 PF13418.6 GAX23268.1 - 8.6e-30 102.5 1.1 4.7e-07 29.7 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX23268.1 - 5e-25 86.9 2.8 2.2e-06 27.7 0.1 5.9 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 GAX23268.1 - 7.9e-25 86.6 4.2 1.6e-06 28.3 0.1 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAX23268.1 - 3.7e-24 84.2 0.3 0.00045 20.1 0.2 6.5 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 GAX23268.1 - 9.2e-21 73.7 6.1 9.2e-21 73.7 6.1 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 GAX23268.1 - 4.8e-17 61.3 0.1 6.1e-05 22.5 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAX23268.1 - 3.1e-11 42.8 6.2 0.039 13.9 0.6 7.1 6 1 0 6 6 6 2 Kelch motif XPG_I PF00867.18 GAX23269.1 - 1.3e-18 67.1 0.1 3.3e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 XPG I-region Chromo_2 PF18704.1 GAX23269.1 - 2.2e-13 50.3 0.0 4.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 XPG_N PF00752.17 GAX23269.1 - 1.1e-07 32.3 0.0 3.6e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain MFS_1 PF07690.16 GAX23270.1 - 1.6e-37 129.2 53.8 8.4e-32 110.5 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX23270.1 - 1.6e-05 24.0 18.8 0.0021 17.0 16.1 3.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 GAX23270.1 - 7.5e-05 21.3 14.6 0.00017 20.2 14.6 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 GAX23270.1 - 0.00038 19.1 5.9 0.00073 18.2 4.6 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein BT1 PF03092.16 GAX23270.1 - 0.0013 17.0 0.7 0.0023 16.3 0.7 1.3 1 0 0 1 1 1 1 BT1 family MFS_1_like PF12832.7 GAX23270.1 - 0.0014 17.6 5.6 0.31 9.8 0.1 4.1 2 2 2 5 5 5 2 MFS_1 like family LacY_symp PF01306.19 GAX23270.1 - 0.0029 16.5 0.4 0.013 14.3 0.4 2.1 1 1 1 2 2 2 1 LacY proton/sugar symporter Fe-ADH PF00465.19 GAX23271.1 - 8.8e-113 376.8 0.5 1.8e-112 375.8 0.1 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 GAX23271.1 - 1.5e-27 96.3 2.1 2.4e-26 92.3 1.3 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 GAX23271.1 - 1.1e-19 71.2 2.5 2.5e-09 37.2 0.5 3.2 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Ribonuc_red_lgN PF00317.21 GAX23271.1 - 0.056 13.5 0.3 0.36 10.9 0.0 2.4 3 0 0 3 3 3 0 Ribonucleotide reductase, all-alpha domain YL1_C PF08265.11 GAX23272.1 - 4.6e-10 39.1 0.0 7.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain PaREP1 PF05942.11 GAX23272.1 - 0.12 12.3 0.3 0.23 11.4 0.3 1.5 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family YjeF_N PF03853.15 GAX23272.1 - 0.15 12.0 0.1 0.33 10.8 0.0 1.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus zf-HIT PF04438.16 GAX23272.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger zf-met PF12874.7 GAX23273.1 - 1.1e-05 25.6 3.3 1.9e-05 24.8 3.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAX23273.1 - 0.00014 22.1 4.2 0.00025 21.2 4.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Rad33 PF08730.10 GAX23273.1 - 0.00033 20.7 0.1 0.00052 20.1 0.1 1.2 1 0 0 1 1 1 1 Rad33 zf-U1 PF06220.12 GAX23273.1 - 0.01 15.6 3.2 0.02 14.6 3.2 1.4 1 0 0 1 1 1 0 U1 zinc finger Cas_Csy4 PF09618.10 GAX23273.1 - 1.7 8.8 13.6 0.031 14.4 4.4 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) AP3D1 PF06375.11 GAX23273.1 - 4.8 7.4 21.0 0.14 12.4 8.5 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF2514 PF10721.9 GAX23273.1 - 5.4 7.0 18.8 0.35 10.9 8.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Peptidase_M8 PF01457.16 GAX23274.1 - 9.8e-08 31.1 0.0 1.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Homeobox_KN PF05920.11 GAX23275.1 - 4.1e-15 55.4 0.1 8.5e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAX23275.1 - 3.5e-06 26.8 0.2 8e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain RCC1 PF00415.18 GAX23276.1 - 1.5e-61 204.8 15.0 5.6e-10 39.7 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX23276.1 - 3.8e-28 96.6 35.2 3.5e-08 33.0 0.8 7.6 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 GAX23276.1 - 0.0087 16.5 0.5 4.5 7.7 0.0 3.5 3 0 0 3 3 3 1 SUKH-3 immunity protein Peptidase_C25_C PF03785.14 GAX23276.1 - 0.43 10.5 1.9 16 5.4 0.0 3.5 3 1 1 4 4 4 0 Peptidase family C25, C terminal ig-like domain DUF4766 PF15973.5 GAX23276.1 - 6.2 7.4 11.1 7.3 7.2 1.2 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4766) tRNA-synt_2 PF00152.20 GAX23277.1 - 4.7e-71 239.4 0.0 9.1e-71 238.5 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX23277.1 - 7.9e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX23277.1 - 0.00049 19.7 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF2514 PF10721.9 GAX23277.1 - 0.019 15.0 3.1 0.045 13.8 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) tRNA_anti_2 PF13742.6 GAX23277.1 - 0.099 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SIMPL PF04402.14 GAX23277.1 - 0.12 12.8 4.5 0.04 14.4 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF541) Ribosomal_L36e PF01158.18 GAX23277.1 - 0.13 12.5 1.8 0.27 11.5 1.8 1.4 1 0 0 1 1 1 0 Ribosomal protein L36e DUF2203 PF09969.9 GAX23277.1 - 0.24 12.2 1.8 2.8 8.7 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) HisKA_2 PF07568.12 GAX23277.1 - 0.32 11.1 1.3 8.4 6.6 0.1 2.6 2 0 0 2 2 2 0 Histidine kinase GDP_Man_Dehyd PF16363.5 GAX23278.1 - 1.3e-68 231.9 0.0 1.5e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX23278.1 - 1.1e-53 182.2 0.0 1.5e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAX23278.1 - 8.7e-21 74.3 0.0 5.4e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAX23278.1 - 1.8e-19 69.8 0.0 2.6e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAX23278.1 - 1.4e-17 63.7 0.0 2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX23278.1 - 2.6e-17 62.8 0.0 3.5e-16 59.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAX23278.1 - 0.0068 16.3 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 GAX23278.1 - 0.032 13.7 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Mre11_DNA_bind PF04152.14 GAX23279.1 - 4.2e-38 131.3 0.1 4.2e-38 131.3 0.1 3.0 3 1 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 GAX23279.1 - 5.9e-12 46.5 0.2 1e-11 45.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX23279.1 - 0.00028 21.1 0.8 0.0046 17.2 0.1 3.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DNA_pol_B PF00136.21 GAX23280.1 - 3.5e-70 237.0 0.0 6.1e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAX23280.1 - 1e-05 24.8 0.0 0.013 14.7 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAX23280.1 - 0.00028 21.3 14.7 0.00095 19.6 14.7 2.0 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Glu_cyclase_2 PF05096.12 GAX23281.1 - 3.8e-67 226.3 0.1 4.9e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase SdiA-regulated PF06977.11 GAX23281.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 SdiA-regulated ThiC-associated PF13667.6 GAX23281.1 - 0.16 11.9 1.4 3.6 7.5 0.2 3.1 3 1 1 4 4 4 0 ThiC-associated domain PPR_long PF17177.4 GAX23282.1 - 0.00056 19.3 1.7 0.64 9.3 0.0 3.6 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GAX23282.1 - 0.00075 19.5 0.0 2 8.6 0.0 4.4 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAX23282.1 - 0.0029 17.8 0.0 1.2 9.4 0.0 4.7 5 0 0 5 5 5 1 PPR repeat family Clathrin PF00637.20 GAX23282.1 - 0.038 13.9 1.4 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS PPR PF01535.20 GAX23282.1 - 0.57 10.5 4.8 13 6.3 0.0 4.9 5 0 0 5 5 5 0 PPR repeat HA2 PF04408.23 GAX23285.1 - 3e-26 91.8 1.2 7.4e-26 90.6 0.1 2.3 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX23285.1 - 2e-23 82.5 0.0 4.9e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX23285.1 - 9e-12 45.3 0.0 3.4e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX23285.1 - 3.1e-06 27.1 0.0 7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX23285.1 - 0.0003 21.1 0.4 0.0017 18.7 0.4 2.2 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX23285.1 - 0.002 17.3 0.0 0.0065 15.6 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 GAX23285.1 - 0.0041 17.5 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain S1 PF00575.23 GAX23285.1 - 0.01 16.2 0.2 0.023 15.0 0.2 1.6 1 0 0 1 1 1 0 S1 RNA binding domain DUF2075 PF09848.9 GAX23285.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 GAX23285.1 - 0.033 13.6 0.1 0.074 12.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 GAX23285.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAX23285.1 - 0.041 13.9 0.5 0.93 9.5 0.3 2.8 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX23285.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 GAX23285.1 - 0.17 12.2 0.4 0.76 10.1 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF2109 PF09882.9 GAX23287.1 - 0.077 13.0 0.5 0.077 13.0 0.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Tetraspanin PF00335.20 GAX23287.1 - 6.5 6.4 7.3 9.2 5.9 2.1 2.2 2 0 0 2 2 2 0 Tetraspanin family MRP-L47 PF06984.13 GAX23288.1 - 3.2e-24 84.9 0.2 4.8e-24 84.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 GAX23288.1 - 0.0046 16.9 0.4 0.01 15.8 0.4 1.6 1 0 0 1 1 1 1 Ribosomal L29 protein SASA PF03629.18 GAX23289.1 - 1.6e-14 54.1 0.0 2.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Peptidase_M16 PF00675.20 GAX23290.1 - 1.4e-19 70.6 0.0 3.7e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M44 PF03410.13 GAX23290.1 - 0.079 11.5 0.0 0.21 10.1 0.0 1.6 2 0 0 2 2 2 0 Metallopeptidase from vaccinia pox Ras PF00071.22 GAX23291.1 - 9e-60 200.9 0.0 1.1e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX23291.1 - 6.4e-33 113.5 0.0 1e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX23291.1 - 1.3e-11 44.2 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX23291.1 - 4.2e-05 23.6 0.0 0.00026 21.0 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX23291.1 - 0.0027 17.1 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAX23291.1 - 0.0033 17.3 0.0 0.31 10.9 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAX23291.1 - 0.0084 15.7 0.0 0.054 13.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAX23291.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX23291.1 - 0.041 13.6 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 GAX23291.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Bcr-Abl_Oligo PF09036.10 GAX23292.1 - 0.033 14.2 0.2 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain PDZ_6 PF17820.1 GAX23292.1 - 0.091 12.6 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 PDZ domain Antimicrobial24 PF16049.5 GAX23292.1 - 5.1 7.2 8.2 12 6.0 8.2 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide SNF2_N PF00176.23 GAX23293.1 - 1.2e-54 185.3 0.0 2.1e-28 99.1 0.0 3.1 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX23293.1 - 9.6e-14 51.7 0.0 5.2e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 GAX23293.1 - 7.4e-09 36.3 0.0 2.9e-08 34.4 0.0 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_3 PF13920.6 GAX23293.1 - 0.00031 20.5 9.2 0.00031 20.5 9.2 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.6 GAX23293.1 - 0.27 11.2 6.6 0.99 9.4 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain AAA PF00004.29 GAX23294.1 - 1e-12 48.6 0.0 4.6e-12 46.5 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX23294.1 - 1.1e-07 31.9 0.1 4e-07 30.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX23294.1 - 5.4e-07 30.0 0.1 3.3e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX23294.1 - 3.6e-06 27.5 0.1 4.9e-05 23.8 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 GAX23294.1 - 7.4e-06 25.2 0.1 1.9e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 GAX23294.1 - 2.7e-05 24.0 0.0 2.7e-05 24.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 GAX23294.1 - 0.00019 21.5 0.3 0.00085 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX23294.1 - 0.001 19.0 0.1 0.0051 16.8 0.1 2.3 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 GAX23294.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 GAX23294.1 - 0.0033 17.2 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX23294.1 - 0.0052 17.0 0.0 0.0052 17.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 GAX23294.1 - 0.0054 17.1 2.7 0.0069 16.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX23294.1 - 0.0062 17.1 0.0 0.0062 17.1 0.0 2.3 3 0 0 3 3 1 1 AAA domain AAA_24 PF13479.6 GAX23294.1 - 0.0064 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAX23294.1 - 0.0069 16.6 0.0 0.024 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX23294.1 - 0.0075 16.1 0.1 0.0075 16.1 0.1 3.8 3 1 0 3 3 2 1 AAA domain Rad17 PF03215.15 GAX23294.1 - 0.011 15.7 0.3 0.076 12.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 GAX23294.1 - 0.017 14.7 0.0 0.047 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAX23294.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAX23294.1 - 0.017 15.6 0.2 1.3 9.6 0.0 3.8 4 0 0 4 4 3 0 ABC transporter AAA_7 PF12775.7 GAX23294.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAX23294.1 - 0.025 14.5 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 1 0 NTPase RsgA_GTPase PF03193.16 GAX23294.1 - 0.035 14.0 0.0 0.097 12.6 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 GAX23294.1 - 0.045 13.5 0.1 3.3 7.4 0.0 2.6 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_2 PF07724.14 GAX23294.1 - 0.061 13.4 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GAX23294.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 GAX23294.1 - 0.071 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC ECR1_N PF14382.6 GAX23295.1 - 2.6e-07 30.3 0.2 8.2e-07 28.7 0.1 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 GAX23295.1 - 3.4e-05 24.4 0.0 0.13 12.9 0.0 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 Calx-beta PF03160.14 GAX23295.1 - 0.11 12.6 0.1 21 5.4 0.0 2.2 2 0 0 2 2 2 0 Calx-beta domain PPP4R2 PF09184.11 GAX23296.1 - 9.3e-11 41.8 0.1 9.3e-11 41.8 0.1 3.4 3 1 0 3 3 3 1 PPP4R2 PQQ_2 PF13360.6 GAX23297.1 - 1.3e-05 24.9 0.1 0.037 13.6 0.0 2.9 3 0 0 3 3 3 2 PQQ-like domain VCBS PF13517.6 GAX23297.1 - 0.00023 21.7 0.0 1.5 9.5 0.0 3.7 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAX23297.1 - 0.016 15.3 4.7 2.3 8.5 0.4 3.3 3 0 0 3 3 3 0 FG-GAP repeat PQQ PF01011.21 GAX23297.1 - 0.13 12.2 0.1 0.83 9.7 0.1 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat zf-ZPR1 PF03367.13 GAX23299.1 - 1.1e-95 317.8 2.1 4.1e-48 163.2 0.4 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain LRR_4 PF12799.7 GAX23301.1 - 0.00014 22.2 2.3 0.14 12.6 0.0 4.4 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX23301.1 - 0.00051 19.8 0.0 0.48 10.2 0.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX23302.1 - 1.1e-08 35.2 0.6 0.091 13.2 0.0 5.2 5 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX23302.1 - 0.0035 17.1 0.1 0.3 10.9 0.0 2.8 3 0 0 3 3 3 2 Leucine rich repeat 2OG-FeII_Oxy_3 PF13640.6 GAX23303.1 - 1.4e-12 48.3 0.0 2.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ENTH PF01417.20 GAX23304.1 - 0.0093 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 ENTH domain CRF PF00473.17 GAX23304.1 - 0.047 13.8 0.1 0.19 11.8 0.1 2.2 1 0 0 1 1 1 0 Corticotropin-releasing factor family HSF_DNA-bind PF00447.17 GAX23305.1 - 4.1e-18 65.8 1.2 8.4e-18 64.8 1.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding GPI2 PF06432.11 GAX23306.1 - 6.1e-30 104.6 9.3 7.3e-30 104.4 9.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1622 PF07784.11 GAX23306.1 - 0.019 14.8 0.1 0.064 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) DUF202 PF02656.15 GAX23306.1 - 0.091 13.2 0.6 0.091 13.2 0.6 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF202) DUF5600 PF18150.1 GAX23307.1 - 2.9e-36 124.3 1.5 5.9e-36 123.3 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 GAX23307.1 - 2.7e-19 69.1 0.0 9.3e-19 67.3 0.0 2.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 GAX23307.1 - 7.8e-15 55.3 0.0 5.5e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin family EHD_N PF16880.5 GAX23307.1 - 2.4e-10 40.1 5.6 4.4e-10 39.3 5.6 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 GAX23307.1 - 6.8e-10 39.0 0.0 1.9e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 GAX23307.1 - 0.00025 20.8 0.7 0.0045 16.8 0.2 2.6 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX23307.1 - 0.0041 16.6 0.4 0.013 15.0 0.4 1.9 1 0 0 1 1 1 1 EF hand Roc PF08477.13 GAX23307.1 - 0.0065 16.7 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 GAX23307.1 - 0.0087 15.6 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B EF-hand_7 PF13499.6 GAX23307.1 - 0.015 15.7 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair AIG1 PF04548.16 GAX23307.1 - 0.051 12.9 0.0 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.27 GAX23307.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain EzrA PF06160.12 GAX23307.1 - 0.073 11.2 0.5 0.2 9.8 0.2 1.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Mito_carr PF00153.27 GAX23308.1 - 1.2e-17 63.6 3.9 2.2e-07 30.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 GAX23309.1 - 6e-08 32.7 0.2 2.9e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX23309.1 - 8.4e-06 26.1 0.1 3.4e-05 24.1 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX23309.1 - 0.00016 21.5 0.0 0.0006 19.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX23309.1 - 0.00019 21.8 0.5 0.0012 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAX23309.1 - 0.0015 17.6 0.0 0.0038 16.3 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 GAX23309.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAX23309.1 - 0.19 12.2 0.0 0.19 12.2 0.0 3.2 2 1 0 2 2 2 0 ABC transporter OB_NTP_bind PF07717.16 GAX23310.1 - 9.1e-22 77.2 0.0 1.8e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAX23310.1 - 1.9e-09 37.7 0.0 3.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Pkinase PF00069.25 GAX23311.1 - 4.6e-76 255.7 0.0 5.8e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23311.1 - 9.4e-33 113.6 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX23311.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX23311.1 - 5.4e-07 29.2 0.0 9.9e-07 28.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAX23311.1 - 0.00017 20.7 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 GAX23311.1 - 0.00063 19.4 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 GAX23311.1 - 0.00064 18.6 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX23311.1 - 0.0098 15.8 0.0 0.045 13.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAX23311.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RAMP4 PF06624.12 GAX23311.1 - 0.029 14.4 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 ubiquitin PF00240.23 GAX23312.1 - 1.1e-33 114.7 0.4 2.3e-33 113.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family Sod_Ni PF09055.11 GAX23312.1 - 9.1e-31 107.1 1.2 1.4e-30 106.4 1.2 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Rad60-SLD PF11976.8 GAX23312.1 - 5.1e-16 58.3 0.7 1e-15 57.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX23312.1 - 3e-05 24.4 0.1 0.00014 22.2 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX23312.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX23312.1 - 0.016 15.3 0.4 0.064 13.4 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAX23312.1 - 0.019 15.3 0.2 0.048 14.0 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 GAX23312.1 - 0.05 14.2 0.0 0.084 13.4 0.0 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX23312.1 - 0.12 12.4 1.3 14 5.8 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-like domain DUF952 PF06108.12 GAX23315.1 - 1.1e-07 31.8 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF952) EutQ PF06249.12 GAX23315.1 - 0.00086 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ hNIFK_binding PF12196.8 GAX23317.1 - 0.14 11.7 1.6 0.34 10.4 0.1 2.5 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK bZIP_1 PF00170.21 GAX23319.1 - 4.7e-07 29.8 6.5 4.7e-07 29.8 6.5 2.7 3 0 0 3 3 3 1 bZIP transcription factor Bap31_Bap29_C PF18035.1 GAX23319.1 - 0.083 12.9 2.4 0.27 11.3 2.4 1.9 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain SET PF00856.28 GAX23320.1 - 4.3e-05 24.0 0.0 0.00018 22.0 0.0 2.0 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.6 GAX23320.1 - 0.023 15.0 0.2 0.064 13.5 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 GAX23320.1 - 0.3 11.5 9.6 0.79 10.1 9.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Plasmid_RAQPRD PF09686.10 GAX23320.1 - 3.4 8.0 8.5 5.8 7.2 0.1 3.5 3 1 1 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) PBP1_TM PF14812.6 GAX23320.1 - 5.1 7.5 6.9 11 6.4 6.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DCP1 PF06058.13 GAX23321.1 - 2.2e-24 85.6 0.1 3.3e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 GAX23321.1 - 0.017 14.4 0.3 0.029 13.7 0.3 1.4 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus SSP160 PF06933.11 GAX23321.1 - 0.018 13.3 0.5 0.024 12.9 0.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 C2 PF00168.30 GAX23322.1 - 5.9e-11 42.6 0.0 1.2e-06 28.8 0.0 2.2 2 0 0 2 2 2 2 C2 domain NRDE-2 PF08424.10 GAX23322.1 - 0.047 12.8 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF4497 PF14924.6 GAX23322.1 - 0.084 13.4 0.0 0.9 10.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) Cupin_8 PF13621.6 GAX23324.1 - 7.6e-10 38.9 0.2 2.9e-09 37.0 0.2 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX23324.1 - 7.3e-05 22.4 3.3 0.00018 21.1 3.3 1.7 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 GAX23324.1 - 0.0047 16.6 0.1 0.0093 15.7 0.1 1.4 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 GAX23324.1 - 0.0071 16.8 2.2 0.065 13.7 0.8 2.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase PT PF04886.12 GAX23325.1 - 0.0025 17.3 75.9 0.11 12.1 11.5 4.8 2 2 2 4 4 4 4 PT repeat AAA PF00004.29 GAX23327.1 - 3.4e-47 160.2 0.0 7e-36 123.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX23327.1 - 6.2e-14 52.7 0.1 9.9e-07 29.3 0.0 3.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAX23327.1 - 1.2e-07 32.1 0.6 0.026 14.8 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX23327.1 - 2.2e-07 31.4 0.0 0.00015 22.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAX23327.1 - 3.9e-05 23.8 0.0 0.0037 17.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 GAX23327.1 - 7.8e-05 23.0 0.0 0.61 10.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 GAX23327.1 - 8.5e-05 22.4 0.0 0.046 13.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 GAX23327.1 - 0.00015 21.9 0.0 0.0085 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAX23327.1 - 0.0026 17.5 0.0 0.03 14.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 GAX23327.1 - 0.0046 16.7 0.0 0.61 9.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 GAX23327.1 - 0.0064 15.9 0.0 0.77 9.1 0.0 3.6 4 0 0 4 4 4 1 Bacterial TniB protein AAA_7 PF12775.7 GAX23327.1 - 0.0071 15.9 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAX23327.1 - 0.01 15.5 0.1 7.5 6.2 0.0 3.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 GAX23327.1 - 0.016 15.2 0.0 0.51 10.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 GAX23327.1 - 0.031 14.6 0.1 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAX23327.1 - 0.036 14.3 0.0 7.7 6.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain T2SSE PF00437.20 GAX23327.1 - 0.091 11.8 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 GAX23327.1 - 0.11 11.6 0.4 2.6 7.2 0.2 2.6 2 1 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 GAX23327.1 - 0.2 11.5 2.0 16 5.3 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAX23327.1 - 4.6 7.1 5.7 30 4.5 0.1 3.6 4 0 0 4 4 4 0 NACHT domain Methyltransf_32 PF13679.6 GAX23328.1 - 3.7e-16 59.5 2.2 3.1e-15 56.5 2.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX23328.1 - 2e-07 31.6 0.3 7e-07 29.9 0.3 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX23328.1 - 2.8e-07 30.4 0.1 7.3e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX23328.1 - 5.1e-05 23.8 0.1 0.00014 22.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX23328.1 - 0.00027 21.6 0.2 0.00077 20.2 0.2 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX23328.1 - 0.0027 17.3 0.3 0.0066 16.0 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAX23328.1 - 0.0029 17.5 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX23329.1 - 3.9e-09 36.5 0.0 6.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAX23329.1 - 1.4e-05 25.0 0.1 0.00033 20.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain RAP80_UIM PF18282.1 GAX23329.1 - 0.04 13.7 1.2 0.093 12.5 1.2 1.6 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Packaging_FI PF14000.6 GAX23329.1 - 0.16 12.4 0.3 0.26 11.8 0.3 1.3 1 0 0 1 1 1 0 DNA packaging protein FI HhH-GPD PF00730.25 GAX23330.1 - 9.9e-21 74.2 0.0 2.3e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAX23330.1 - 0.00018 21.2 0.0 0.00038 20.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif FAM176 PF14851.6 GAX23330.1 - 0.082 12.6 1.7 0.19 11.4 1.7 1.6 1 0 0 1 1 1 0 FAM176 family Sh_2 PF17512.2 GAX23330.1 - 0.16 11.7 0.9 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein Peptidase_S30 PF01577.16 GAX23330.1 - 0.46 10.0 7.0 1 8.9 7.0 1.5 1 0 0 1 1 1 0 Potyvirus P1 protease Tox-REase-2 PF15646.6 GAX23333.1 - 0.028 14.6 0.0 0.098 12.8 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 FAD_binding_7 PF03441.14 GAX23334.1 - 3.5e-59 199.7 1.1 5.4e-59 199.1 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAX23334.1 - 3.8e-33 114.8 0.6 1.3e-32 113.1 0.0 2.0 3 0 0 3 3 3 1 DNA photolyase RAM PF15320.6 GAX23334.1 - 1.8 9.2 5.9 1.5 9.5 0.8 2.5 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Alba PF01918.21 GAX23335.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Alba Cytidylate_kin2 PF13189.6 GAX23335.1 - 0.066 13.3 0.2 0.12 12.5 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase-like family bZIP_1 PF00170.21 GAX23336.1 - 7e-07 29.3 3.6 2e-06 27.8 3.6 1.8 1 0 0 1 1 1 1 bZIP transcription factor Phage_GPO PF05929.11 GAX23336.1 - 0.00054 19.7 1.9 0.00085 19.0 1.4 1.6 1 1 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase bZIP_2 PF07716.15 GAX23336.1 - 0.015 15.4 5.8 0.015 15.4 5.8 2.2 3 0 0 3 3 3 0 Basic region leucine zipper rpo30_N PF12410.8 GAX23336.1 - 0.066 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Tox-REase-9 PF15650.6 GAX23336.1 - 0.15 12.4 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 bZIP_1 PF00170.21 GAX23337.1 - 0.00025 21.1 9.2 0.00025 21.1 9.2 2.1 3 0 0 3 3 3 1 bZIP transcription factor Pyrid_oxidase_2 PF13883.6 GAX23338.1 - 2.1e-18 66.8 0.0 4.4e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 GAX23338.1 - 3.3e-13 50.1 0.0 6.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 GAX23338.1 - 2.2e-08 34.2 0.0 1e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase ubiquitin PF00240.23 GAX23339.1 - 2.7e-159 517.2 23.5 3.4e-13 49.1 0.0 14.6 14 1 0 14 14 14 14 Ubiquitin family Rad60-SLD PF11976.8 GAX23339.1 - 1.7e-89 293.7 15.4 2.5e-09 36.8 0.1 14.3 14 0 0 14 14 14 12 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX23339.1 - 6.1e-41 138.8 14.0 0.0056 17.1 0.2 13.9 13 0 0 13 13 13 9 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX23339.1 - 4.5e-28 97.0 0.0 0.012 15.5 0.0 11.7 11 1 1 12 12 12 5 TANK binding kinase 1 ubiquitin-like domain UN_NPL4 PF11543.8 GAX23339.1 - 7.6e-21 74.4 0.1 1.6 9.2 0.0 12.2 10 3 3 13 13 12 2 Nuclear pore localisation protein NPL4 Ubiquitin_4 PF18036.1 GAX23339.1 - 3.1e-16 59.2 19.9 0.085 12.9 0.0 14.9 13 4 0 13 13 13 2 Ubiquitin-like domain UBX PF00789.20 GAX23339.1 - 8.7e-12 45.1 0.0 1.9 8.7 0.0 10.3 11 2 2 13 13 13 2 UBX domain TUG-UBL1 PF11470.8 GAX23339.1 - 2.5e-11 43.6 0.0 2.2 8.6 0.0 9.8 11 0 0 11 11 11 1 TUG ubiquitin-like domain FERM_N PF09379.10 GAX23339.1 - 9.8e-08 31.8 1.1 1.1 9.3 0.0 8.6 10 0 0 10 10 10 1 FERM N-terminal domain RBD PF02196.15 GAX23339.1 - 1.9e-07 31.1 1.8 13 5.9 0.0 6.0 5 0 0 5 5 5 0 Raf-like Ras-binding domain GABP-alpha PF11620.8 GAX23339.1 - 4.8e-05 23.5 5.3 1.8 8.8 0.0 6.9 7 1 1 8 8 8 1 GA-binding protein alpha chain Coilin_N PF15862.5 GAX23339.1 - 0.0016 18.2 0.3 11 5.8 0.0 5.7 6 0 0 6 6 6 0 Coilin N-terminus Raf1_HTH PF18579.1 GAX23339.1 - 0.0046 16.6 1.9 29 4.5 0.0 5.4 6 0 0 6 6 6 0 Rubisco accumulation factor 1 helix turn helix domain Ubiquitin_5 PF18037.1 GAX23339.1 - 0.034 14.5 3.5 57 4.2 0.0 5.8 7 0 0 7 7 5 0 Ubiquitin-like domain Rootletin PF15035.6 GAX23339.1 - 0.063 13.3 3.1 0.18 11.8 3.1 1.7 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TmoB PF06234.12 GAX23339.1 - 0.1 12.7 4.1 66 3.7 0.0 5.7 6 0 0 6 6 6 0 Toluene-4-monooxygenase system protein B (TmoB) HMA PF00403.26 GAX23339.1 - 0.12 12.9 1.0 14 6.3 0.1 4.9 4 0 0 4 4 4 0 Heavy-metal-associated domain DUF2501 PF10696.9 GAX23339.1 - 0.19 12.0 1.9 8.7 6.7 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2501) F-box-like PF12937.7 GAX23340.1 - 0.24 11.3 1.6 0.51 10.3 1.6 1.6 1 0 0 1 1 1 0 F-box-like RB_B PF01857.20 GAX23341.1 - 1.5e-25 89.7 0.6 6.3e-25 87.7 0.0 2.3 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain RB_A PF01858.17 GAX23341.1 - 1.4e-20 74.0 0.4 4.2e-20 72.4 0.4 1.8 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain ROKNT PF08067.11 GAX23341.1 - 0.018 15.3 1.4 0.038 14.3 1.4 1.5 1 0 0 1 1 1 0 ROKNT (NUC014) domain LRR_8 PF13855.6 GAX23342.1 - 7.8e-29 99.2 54.9 6.7e-05 22.6 3.7 9.7 8 2 1 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 GAX23342.1 - 1.8e-23 82.2 57.0 2.4e-05 24.6 0.8 12.5 7 3 7 15 15 15 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX23342.1 - 4.5e-09 35.6 31.7 8.4 7.4 0.0 15.4 18 1 0 18 18 18 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX23342.1 - 0.0072 16.3 43.9 14 6.1 0.1 15.1 17 0 0 17 17 17 3 Leucine Rich repeat Ank_2 PF12796.7 GAX23344.1 - 0.0029 18.1 0.0 0.85 10.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX23344.1 - 0.14 12.8 0.0 3.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) UBA PF00627.31 GAX23344.1 - 0.87 9.6 3.9 1.8 8.6 0.0 2.7 3 0 0 3 3 3 0 UBA/TS-N domain CSRNP_N PF16019.5 GAX23345.1 - 1.5e-05 25.0 31.5 8.2e-05 22.6 0.0 5.9 3 2 2 5 5 5 1 Cysteine/serine-rich nuclear protein N-terminus Presenilin PF01080.17 GAX23345.1 - 0.74 8.5 3.1 1.2 7.8 3.1 1.3 1 0 0 1 1 1 0 Presenilin AP3D1 PF06375.11 GAX23345.1 - 1.1 9.5 14.9 0.16 12.2 10.3 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PH PF00169.29 GAX23346.1 - 5.9e-12 46.0 0.5 6.1e-11 42.8 0.5 2.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 GAX23346.1 - 0.014 15.8 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 GAX23346.1 - 0.063 13.6 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Patatin PF01734.22 GAX23347.1 - 8.7e-25 88.1 0.2 2.8e-24 86.4 0.2 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase His_Phos_1 PF00300.22 GAX23348.1 - 7.4e-59 198.7 0.0 2.7e-24 85.9 0.0 4.3 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) TPR_8 PF13181.6 GAX23349.1 - 2.4e-06 27.3 0.6 0.0001 22.2 0.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX23349.1 - 2.6e-05 24.0 1.4 0.00062 19.7 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23349.1 - 0.00032 20.4 0.1 0.014 15.2 0.5 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23349.1 - 0.0087 16.3 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23349.1 - 0.021 15.4 0.3 1.2 9.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PNKP-ligase_C PF16536.5 GAX23349.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, C-terminal region TPR_7 PF13176.6 GAX23349.1 - 0.1 12.7 0.0 0.38 10.9 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SURF1 PF02104.15 GAX23350.1 - 1.1e-33 116.9 0.1 1.4e-33 116.6 0.1 1.0 1 0 0 1 1 1 1 SURF1 family Cupin_3 PF05899.12 GAX23351.1 - 7.5e-31 105.7 5.6 2e-15 56.2 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GAX23351.1 - 2.7e-11 43.0 0.0 5.2e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.7 GAX23351.1 - 0.0038 17.0 0.3 2.6 7.7 0.0 2.3 2 0 0 2 2 2 2 Cupin EutQ PF06249.12 GAX23351.1 - 0.051 13.3 0.0 2.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 GAX23351.1 - 0.085 12.8 0.6 0.38 10.6 0.2 2.2 3 0 0 3 3 3 0 AraC-like ligand binding domain Sulfotransfer_4 PF17784.1 GAX23352.1 - 8.7e-42 143.4 0.0 1.4e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX23352.1 - 0.0067 16.8 0.2 0.5 10.7 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family DUF924 PF06041.11 GAX23353.1 - 4.4e-40 137.7 0.0 5.2e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF4954 PF16314.5 GAX23354.1 - 2.6e-23 82.1 0.0 1.1e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) EB1 PF03271.17 GAX23355.1 - 1e-11 44.9 0.4 2.4e-11 43.7 0.4 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 GAX23355.1 - 1.5e-06 28.3 0.4 1e-05 25.7 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain ERM PF00769.19 GAX23355.1 - 0.00037 20.4 1.5 0.00055 19.8 1.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2353 PF09789.9 GAX23355.1 - 0.0014 18.1 1.0 0.0026 17.2 1.0 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) JIP_LZII PF16471.5 GAX23355.1 - 0.044 14.0 5.7 0.082 13.1 5.7 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II CAMSAP_CH PF11971.8 GAX23355.1 - 0.06 13.2 0.1 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 CAMSAP CH domain HALZ PF02183.18 GAX23355.1 - 0.069 13.4 6.6 1.1 9.6 3.0 3.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GAX23355.1 - 0.19 11.8 2.6 0.41 10.8 2.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor APG6_N PF17675.1 GAX23355.1 - 0.32 11.5 7.1 0.59 10.7 7.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 GAX23355.1 - 0.92 10.0 8.3 2.9 8.4 8.3 1.9 1 1 0 1 1 1 0 Cell division protein ZapB PfkB PF00294.24 GAX23357.1 - 9.9e-10 38.2 0.0 7.6e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PhyH PF05721.13 GAX23359.1 - 1.2e-12 48.6 0.0 1.6e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SWIB PF02201.18 GAX23360.1 - 7.2e-11 41.8 0.0 2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Peptidase_C48 PF02902.19 GAX23363.1 - 1.4e-32 113.3 1.5 1.4e-32 113.3 1.5 2.0 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Ead_Ea22 PF13935.6 GAX23363.1 - 0.051 14.2 1.0 0.12 13.0 1.0 1.6 1 0 0 1 1 1 0 Ead/Ea22-like protein TIP_N PF12457.8 GAX23364.1 - 0.08 13.3 2.2 0.15 12.4 2.2 1.4 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal GatD_N PF18195.1 GAX23364.1 - 0.13 11.6 0.1 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 GatD N-terminal domain Creb_binding PF09030.10 GAX23365.1 - 0.0018 18.9 0.0 0.0031 18.2 0.0 1.3 1 0 0 1 1 1 1 Creb binding DUF3181 PF11378.8 GAX23365.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) UPF0020 PF01170.18 GAX23366.1 - 4e-27 95.2 0.0 5.8e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 GAX23366.1 - 4.6e-06 26.1 0.1 0.0019 17.5 0.0 2.5 2 1 0 2 2 2 2 N-6 DNA Methylase N6_N4_Mtase PF01555.18 GAX23366.1 - 0.081 12.6 0.4 0.39 10.4 0.0 2.2 3 0 0 3 3 3 0 DNA methylase SufE PF02657.15 GAX23367.1 - 2.9e-31 107.9 0.0 4.6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 GAX23367.1 - 1.9e-25 88.9 0.0 3.3e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein SufE PF02657.15 GAX23368.1 - 5.6e-28 97.2 0.0 7.4e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Fe-S metabolism associated domain Adaptin_binding PF10199.9 GAX23369.1 - 0.0056 17.3 0.0 0.13 12.9 0.0 2.4 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 EcKinase PF02958.20 GAX23370.1 - 2.2e-17 63.3 0.3 3.2e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 GAX23370.1 - 1e-07 32.1 3.7 2.1e-07 31.1 3.7 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAX23370.1 - 1.3e-06 27.6 0.0 2.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 GAX23370.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF436 PF04260.12 GAX23370.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Methyltransf_25 PF13649.6 GAX23371.1 - 0.026 15.2 0.0 0.12 13.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAX23371.1 - 0.036 13.9 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAX23371.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GFA PF04828.14 GAX23373.1 - 1.4e-11 44.5 1.2 2e-11 44.0 1.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fer2_3 PF13085.6 GAX23373.1 - 0.24 11.4 2.5 0.34 10.9 2.5 1.4 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PRKCSH PF07915.13 GAX23375.1 - 2.1e-18 67.1 0.3 8.2e-10 39.6 0.0 2.7 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 GAX23375.1 - 5.8e-07 29.3 3.1 0.012 15.3 0.3 4.1 3 1 0 3 3 3 2 Glucosidase II beta subunit-like protein Cupin_2 PF07883.11 GAX23376.1 - 0.00013 21.6 0.1 0.0006 19.5 0.1 1.9 1 1 0 2 2 2 1 Cupin domain CLPTM1 PF05602.12 GAX23377.1 - 2.6e-63 214.5 0.8 5.4e-59 200.3 0.3 4.1 2 1 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 GAX23377.1 - 6.6e-05 22.6 0.9 0.22 11.3 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat GAF PF01590.26 GAX23378.1 - 3.7e-07 30.9 0.0 1e-06 29.4 0.0 1.7 2 0 0 2 2 2 1 GAF domain DUF2461 PF09365.10 GAX23378.1 - 0.06 13.3 0.2 0.086 12.8 0.2 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) SBF PF01758.16 GAX23379.1 - 2.3e-25 89.5 10.2 2.3e-25 89.5 10.2 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 GAX23379.1 - 0.00098 17.6 13.1 0.0042 15.5 7.0 2.2 2 0 0 2 2 2 2 Membrane transport protein Holin_BlyA PF05102.12 GAX23379.1 - 0.79 9.7 2.9 5.9 6.9 0.1 2.7 3 0 0 3 3 3 0 holin, BlyA family FA_desaturase PF00487.24 GAX23380.1 - 1.4e-25 90.6 22.1 5.7e-25 88.6 22.1 2.3 1 1 0 1 1 1 1 Fatty acid desaturase FA_hydroxylase PF04116.13 GAX23380.1 - 0.051 13.9 0.9 0.051 13.9 0.9 3.3 3 1 1 4 4 4 0 Fatty acid hydroxylase superfamily FKBP_C PF00254.28 GAX23381.1 - 3.5e-30 104.2 0.0 6.5e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Linker_histone PF00538.19 GAX23381.1 - 2.3e-09 37.5 0.7 3e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 linker histone H1 and H5 family PDZ_2 PF13180.6 GAX23381.1 - 0.063 13.6 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 PDZ domain TMEM151 PF14857.6 GAX23382.1 - 6.3e-06 25.4 3.6 0.0033 16.4 1.2 2.3 2 0 0 2 2 2 2 TMEM151 family adh_short PF00106.25 GAX23383.1 - 6.6e-31 107.3 0.1 1.2e-30 106.4 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX23383.1 - 5.9e-26 91.5 0.0 8.4e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX23383.1 - 3.2e-05 23.9 0.1 4.5e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX23383.1 - 0.00019 21.0 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX23383.1 - 0.004 16.6 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF445 PF04286.12 GAX23384.1 - 7.4e-15 55.6 1.6 0.00025 21.0 0.1 4.2 2 2 2 4 4 4 4 Protein of unknown function (DUF445) PRANC PF09372.10 GAX23384.1 - 0.086 13.2 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 PRANC domain EnY2 PF10163.9 GAX23384.1 - 0.18 12.2 0.3 7.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Transcription factor e(y)2 SBF PF01758.16 GAX23385.1 - 5.2e-24 85.0 9.1 5.2e-24 85.0 9.1 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 GAX23385.1 - 2.7e-10 40.1 17.7 4.1e-10 39.5 17.7 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 GAX23385.1 - 5.4e-05 21.8 2.7 5.4e-05 21.8 2.7 2.3 1 1 1 2 2 2 1 Membrane transport protein DUF4231 PF14015.6 GAX23385.1 - 1.5 9.3 13.5 2.8 8.5 4.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) HLH PF00010.26 GAX23386.1 - 7.1e-05 22.7 3.7 7.8e-05 22.5 1.4 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 GAX23386.1 - 0.008 16.4 0.2 0.038 14.2 0.1 2.2 2 1 0 2 2 2 1 PAS domain PAS_8 PF13188.7 GAX23386.1 - 0.012 15.6 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 GAX23386.1 - 0.014 15.4 0.0 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 PAS fold Dsh_C PF12316.8 GAX23386.1 - 0.45 10.9 4.2 0.88 9.9 4.2 1.6 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Mcm10 PF09332.11 GAX23386.1 - 3.7 6.9 13.9 0.031 13.7 5.6 1.7 2 0 0 2 2 2 0 Mcm10 replication factor HLH PF00010.26 GAX23387.1 - 1.4e-07 31.4 1.0 2.9e-07 30.3 1.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 GAX23387.1 - 0.031 14.5 0.0 0.099 12.9 0.0 1.8 1 0 0 1 1 1 0 PAS domain Ribosomal_L44 PF00935.19 GAX23388.1 - 4.5e-32 110.4 12.6 6e-32 110.0 12.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Sar8_2 PF03058.14 GAX23388.1 - 0.79 10.3 5.7 1.5 9.4 5.7 1.6 1 1 0 1 1 1 0 Sar8.2 family Acylphosphatase PF00708.18 GAX23389.1 - 4e-10 40.0 0.2 5.7e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Acylphosphatase RIBIOP_C PF04950.12 GAX23389.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Glyco_trans_2_3 PF13632.6 GAX23390.1 - 1.4e-24 87.1 0.7 4e-24 85.6 0.7 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX23390.1 - 1.5e-19 70.8 0.0 2.2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX23390.1 - 1.3e-14 54.4 0.0 2.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX23390.1 - 1.2e-09 37.9 0.0 2.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 SPC25 PF06703.11 GAX23390.1 - 0.013 15.3 0.0 0.013 15.3 0.0 2.2 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4440 PF14534.6 GAX23391.1 - 5.8e-05 23.5 0.0 0.36 11.2 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4440) SnoaL PF07366.12 GAX23391.1 - 0.06 13.1 0.1 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Urocanase PF01175.18 GAX23392.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain RNA_pol_A_CTD PF03118.15 GAX23393.1 - 0.053 13.3 0.2 8.8 6.2 0.3 2.4 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain MreD PF04093.12 GAX23394.1 - 0.18 11.9 0.2 0.18 11.9 0.2 1.7 2 0 0 2 2 2 0 rod shape-determining protein MreD TPR_2 PF07719.17 GAX23395.1 - 8.4e-12 44.2 9.6 0.0035 17.3 0.1 7.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAX23395.1 - 4e-11 42.8 21.5 0.0018 19.0 1.6 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX23395.1 - 1.3e-08 34.4 1.1 0.0028 17.3 0.0 6.5 5 2 1 6 6 6 1 TPR repeat TPR_12 PF13424.6 GAX23395.1 - 7.5e-08 32.6 12.0 0.00064 20.0 0.0 6.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23395.1 - 8e-07 28.8 4.2 4.5 7.8 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX23395.1 - 1.6e-06 28.7 23.5 0.39 11.4 0.1 7.3 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23395.1 - 9.6e-06 25.2 5.4 0.78 9.7 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23395.1 - 2.3e-05 24.1 2.1 1 9.6 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX23395.1 - 0.00024 21.2 0.7 50 4.6 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX23395.1 - 0.00054 20.4 20.3 0.03 14.8 1.8 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23395.1 - 0.025 15.2 11.2 11 6.8 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Sel1 PF08238.12 GAX23395.1 - 0.25 12.1 1.8 14 6.6 0.1 4.2 5 0 0 5 5 3 0 Sel1 repeat TPR_9 PF13371.6 GAX23395.1 - 0.76 10.0 9.2 7 6.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.18 GAX23396.1 - 4.6e-10 39.4 14.7 4.6e-10 39.4 14.7 2.7 2 1 0 2 2 2 1 MYND finger zf-C3HC4_3 PF13920.6 GAX23396.1 - 3.1e-08 33.3 4.4 3.1e-08 33.3 4.4 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX23396.1 - 1.6e-06 28.3 6.3 1.6e-06 28.3 6.3 2.5 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX23396.1 - 1.7e-06 28.0 4.1 1.9e-06 27.8 2.3 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX23396.1 - 2.2e-06 27.4 6.4 2.2e-06 27.4 6.4 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 GAX23396.1 - 3.3e-06 26.8 6.1 0.86 9.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23396.1 - 3.1e-05 24.2 6.1 0.099 12.9 0.9 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 GAX23396.1 - 7.8e-05 22.6 6.8 7.8e-05 22.6 6.8 2.5 2 0 0 2 2 1 1 zinc-RING finger domain TPR_14 PF13428.6 GAX23396.1 - 9.6e-05 22.9 6.5 1.2 10.2 0.3 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX23396.1 - 0.00037 20.9 4.3 0.023 15.2 1.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 GAX23396.1 - 0.00089 19.1 9.7 0.00089 19.1 9.7 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.6 GAX23396.1 - 0.0011 19.6 0.9 1.9 9.2 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat FAM76 PF16046.5 GAX23396.1 - 0.0067 15.8 0.6 0.0067 15.8 0.6 2.1 2 0 0 2 2 1 1 FAM76 protein TPR_7 PF13176.6 GAX23396.1 - 0.015 15.3 0.7 29 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23396.1 - 0.035 14.7 8.3 0.84 10.4 0.7 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-MIZ PF02891.20 GAX23396.1 - 0.038 13.8 3.7 0.14 12.0 3.7 2.0 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 GAX23396.1 - 0.048 13.4 6.1 0.12 12.2 6.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 GAX23396.1 - 0.097 12.5 2.6 0.22 11.3 2.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_4 PF07721.14 GAX23396.1 - 0.11 13.2 9.0 1.3 9.8 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23396.1 - 0.85 9.5 6.3 73 3.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX23396.1 - 6.2 6.8 10.5 21 5.2 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GAX23396.1 - 6.8 6.6 12.9 0.04 13.8 3.5 2.2 2 1 0 2 2 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAX23396.1 - 7 7.0 13.0 0.045 14.0 3.5 2.4 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-C2H2_3 PF13878.6 GAX23396.1 - 9.8 6.1 8.8 1.3 8.9 3.6 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Alk_phosphatase PF00245.20 GAX23397.1 - 7e-31 107.6 6.1 1.1e-15 57.5 0.1 3.2 3 0 0 3 3 3 3 Alkaline phosphatase GDPD PF03009.17 GAX23397.1 - 3.6e-18 66.2 0.0 9.4e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Metalloenzyme PF01676.18 GAX23397.1 - 0.00063 19.2 0.7 0.0031 16.9 0.0 2.2 2 1 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 GAX23397.1 - 0.0072 15.7 0.3 0.079 12.3 0.4 2.2 2 0 0 2 2 2 1 Sulfatase Cyclin_N PF00134.23 GAX23398.1 - 2e-05 24.3 1.9 0.0021 17.8 0.1 3.1 3 0 0 3 3 3 1 Cyclin, N-terminal domain Tcf25 PF04910.14 GAX23398.1 - 0.12 11.4 0.4 0.18 10.8 0.1 1.5 2 0 0 2 2 2 0 Transcriptional repressor TCF25 Methyltransf_16 PF10294.9 GAX23399.1 - 2.6e-25 89.1 0.0 1.5e-16 60.6 0.0 2.2 1 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 GAX23399.1 - 0.0025 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX23399.1 - 0.028 15.1 0.0 0.15 12.8 0.0 2.1 1 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX23399.1 - 0.041 14.6 0.0 0.17 12.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 GAX23399.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 GAX23399.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain LRR_8 PF13855.6 GAX23400.1 - 2.7e-22 78.3 9.1 6.1e-07 29.1 0.0 4.0 1 1 3 4 4 4 4 Leucine rich repeat Pkinase PF00069.25 GAX23400.1 - 1.4e-11 44.3 0.0 2.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 GAX23400.1 - 3.9e-10 39.8 10.2 0.001 19.4 1.1 5.1 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 GAX23400.1 - 1.3e-05 24.7 0.0 4.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_9 PF14580.6 GAX23400.1 - 0.00015 21.3 2.5 0.23 11.0 0.5 2.7 1 1 1 2 2 2 2 Leucine-rich repeat Kdo PF06293.14 GAX23400.1 - 0.00033 20.1 0.2 0.00056 19.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX23400.1 - 0.0036 17.3 0.1 0.011 15.7 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family LRR_5 PF13306.6 GAX23400.1 - 0.1 12.6 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 GAX23400.1 - 1.7 9.5 8.7 66 4.7 0.1 5.8 5 2 0 5 5 5 0 Leucine Rich Repeat START PF01852.19 GAX23401.1 - 0.00019 20.9 0.0 0.00033 20.1 0.0 1.5 1 1 0 1 1 1 1 START domain DNA_mis_repair PF01119.19 GAX23402.1 - 1.8e-21 76.0 0.0 3.7e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 GAX23402.1 - 2.6e-19 69.4 0.0 1.6e-17 63.7 0.0 2.7 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 GAX23402.1 - 7.8e-05 23.2 0.0 0.00021 21.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX23402.1 - 9.1e-05 22.3 0.0 0.00035 20.4 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ResIII PF04851.15 GAX23403.1 - 7e-22 78.2 0.0 1.8e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX23403.1 - 3.2e-19 69.3 1.5 6.3e-19 68.4 0.7 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX23403.1 - 1.1e-15 57.8 0.0 2.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 GAX23403.1 - 8.8e-06 25.5 8.2 8.8e-06 25.5 8.2 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 GAX23403.1 - 2.6e-05 23.7 5.0 7.2e-05 22.3 5.0 1.8 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 GAX23403.1 - 0.057 13.6 4.7 0.45 10.7 0.0 2.9 3 0 0 3 3 3 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 GAX23403.1 - 0.8 10.1 4.2 2.8 8.3 4.2 2.0 1 0 0 1 1 1 0 RING-like domain Asp_protease_2 PF13650.6 GAX23406.1 - 8.5e-20 71.2 1.7 5.2e-12 46.2 0.2 2.7 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAX23406.1 - 3.6e-15 56.3 0.5 1.2e-07 32.2 0.0 3.1 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease RVP PF00077.20 GAX23406.1 - 0.0044 17.3 0.0 2 8.8 0.0 2.6 3 0 0 3 3 3 2 Retroviral aspartyl protease RVP_2 PF08284.11 GAX23406.1 - 0.017 14.9 0.0 4.7 7.0 0.0 2.7 3 0 0 3 3 3 0 Retroviral aspartyl protease DUF1758 PF05585.12 GAX23406.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF5011 PF16403.5 GAX23406.1 - 0.2 11.8 0.0 0.89 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Spc7 PF08317.11 GAX23407.1 - 0.0022 16.9 208.5 0.14 11.0 25.0 10.1 1 1 9 10 10 10 7 Spc7 kinetochore protein Tup_N PF08581.10 GAX23407.1 - 0.0039 17.5 9.4 0.0039 17.5 9.4 16.1 10 8 5 15 15 15 3 Tup N-terminal Nup54 PF13874.6 GAX23407.1 - 0.0045 17.1 14.3 0.0045 17.1 14.3 10.6 3 3 4 9 9 9 1 Nucleoporin complex subunit 54 Fib_alpha PF08702.10 GAX23407.1 - 0.0049 17.0 4.5 0.0049 17.0 4.5 11.5 3 2 8 12 12 12 3 Fibrinogen alpha/beta chain family KASH_CCD PF14662.6 GAX23407.1 - 0.0055 16.6 12.6 0.0055 16.6 12.6 9.8 3 2 6 10 10 10 1 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 GAX23407.1 - 0.0055 16.3 37.3 0.0055 16.3 37.3 8.5 1 1 8 9 9 9 3 Intermediate filament protein JIP_LZII PF16471.5 GAX23407.1 - 0.0059 16.8 8.5 0.0059 16.8 8.5 16.7 13 4 5 19 19 19 2 JNK-interacting protein leucine zipper II DUF4200 PF13863.6 GAX23407.1 - 0.0091 16.4 16.2 0.0091 16.4 16.2 13.6 3 2 10 13 13 13 1 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 GAX23407.1 - 0.015 15.3 0.8 0.015 15.3 0.8 18.7 9 6 10 19 19 19 0 TATA element modulatory factor 1 DNA binding Orn_Arg_deC_N PF02784.16 GAX23408.1 - 2.6e-65 220.2 0.0 7.9e-65 218.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAX23408.1 - 9.4e-13 48.2 0.0 2.9e-11 43.5 0.0 2.5 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Choline_transpo PF04515.12 GAX23409.1 - 1.7e-14 53.8 14.1 2.2e-13 50.2 14.1 2.4 1 1 0 1 1 1 1 Plasma-membrane choline transporter Arm PF00514.23 GAX23410.1 - 3e-97 316.1 15.8 2.3e-12 46.5 0.2 8.5 9 0 0 9 9 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAX23410.1 - 1.5e-34 117.9 3.0 3.6e-11 43.3 0.0 7.0 5 2 2 7 7 7 6 HEAT-like repeat HEAT_2 PF13646.6 GAX23410.1 - 7e-25 87.2 0.1 4.4e-08 33.4 0.0 5.7 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 GAX23410.1 - 4.1e-23 79.5 4.0 3.1e-05 23.9 0.0 8.1 8 0 0 8 8 8 4 HEAT repeat IBB PF01749.20 GAX23410.1 - 2e-19 69.8 1.0 1.1e-18 67.5 1.2 2.2 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 GAX23410.1 - 4.7e-18 64.5 1.1 9e-17 60.4 3.3 2.0 2 0 0 2 2 2 1 Atypical Arm repeat Arm_2 PF04826.13 GAX23410.1 - 4.8e-11 42.6 0.1 0.00075 19.0 0.0 3.8 1 1 4 5 5 5 2 Armadillo-like Cnd1 PF12717.7 GAX23410.1 - 2.5e-08 34.1 0.0 0.022 14.8 0.0 3.8 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAX23410.1 - 8.4e-08 31.2 0.0 0.0052 15.4 0.0 3.1 1 1 2 3 3 3 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 GAX23410.1 - 3.6e-07 30.3 0.0 3 8.0 0.0 4.3 3 1 2 5 5 5 4 V-ATPase subunit H RICTOR_V PF14668.6 GAX23410.1 - 3.6e-05 23.9 1.7 2.5 8.4 0.0 5.1 4 2 3 7 7 6 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 GAX23410.1 - 0.00013 22.3 0.1 1 10.2 0.0 5.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 GAX23410.1 - 0.00017 21.6 0.1 1.6 8.8 0.2 3.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain NopRA1 PF16201.5 GAX23410.1 - 0.00063 19.4 0.0 47 3.5 0.0 5.4 4 2 2 6 6 6 0 Nucleolar pre-ribosomal-associated protein 1 Mo25 PF08569.11 GAX23410.1 - 0.00069 19.1 0.0 0.031 13.6 0.0 2.4 1 1 1 2 2 2 1 Mo25-like Vps35 PF03635.17 GAX23410.1 - 0.017 13.7 0.0 0.053 12.0 0.0 1.3 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Nipped-B_C PF12830.7 GAX23410.1 - 0.18 11.7 0.0 1.4 8.8 0.0 2.3 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus F-actin_cap_A PF01267.17 GAX23412.1 - 7.5e-20 71.5 1.6 3.7e-18 65.9 1.6 2.1 1 1 0 1 1 1 1 F-actin capping protein alpha subunit DUF1993 PF09351.10 GAX23412.1 - 0.1 12.7 3.5 0.21 11.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Beta_helix PF13229.6 GAX23413.1 - 1.5e-09 37.9 2.3 3.8e-09 36.6 2.3 1.6 1 1 0 1 1 1 1 Right handed beta helix region LRR_8 PF13855.6 GAX23414.1 - 1.5e-09 37.5 8.2 3.2e-05 23.6 6.9 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAX23414.1 - 1.2e-06 28.7 10.0 0.00088 19.6 2.1 3.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX23414.1 - 1.1e-05 25.3 3.3 0.59 10.9 0.1 5.9 5 1 0 5 5 5 1 Leucine Rich Repeat HHV-5_US34A PF17087.5 GAX23414.1 - 0.18 11.9 0.1 0.28 11.4 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus US34A protein family LRR_6 PF13516.6 GAX23414.1 - 0.57 10.4 4.2 10 6.5 0.9 3.1 2 0 0 2 2 2 0 Leucine Rich repeat ubiquitin PF00240.23 GAX23417.1 - 8.7e-08 31.8 0.1 1.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX23417.1 - 5.3e-06 26.2 0.2 3.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 GAX23417.1 - 0.011 16.5 0.4 0.03 15.0 0.4 1.9 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ribosomal_L22 PF00237.19 GAX23418.1 - 1.4e-33 115.2 0.2 1.9e-33 114.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Amidohydro_3 PF07969.11 GAX23418.1 - 0.0025 17.4 0.1 0.0026 17.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Sigma70_r2 PF04542.14 GAX23419.1 - 1.5e-05 24.7 0.4 0.00025 20.7 0.1 2.7 2 1 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GAX23419.1 - 0.0021 17.5 0.1 0.054 13.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Asn_synthase PF00733.21 GAX23419.1 - 0.0078 15.9 1.2 0.011 15.4 1.2 1.4 1 0 0 1 1 1 1 Asparagine synthase Sigma70_r3 PF04539.16 GAX23419.1 - 0.031 14.4 5.5 0.1 12.7 0.1 3.6 4 0 0 4 4 4 0 Sigma-70 region 3 Asp_protease_2 PF13650.6 GAX23421.1 - 0.0068 17.0 0.0 5.2 7.8 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease Rotamase PF00639.21 GAX23422.1 - 4.9e-16 59.5 0.0 7.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX23422.1 - 1.2e-12 48.4 0.0 1.7e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAX23422.1 - 0.0002 22.2 0.0 0.00032 21.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain HSF_DNA-bind PF00447.17 GAX23423.1 - 1.4e-12 48.1 0.0 2.1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Peptidase_C26 PF07722.13 GAX23424.1 - 6.9e-11 42.3 0.0 2.4e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 GAX23424.1 - 7.4e-09 35.7 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 GAX23424.1 - 0.00086 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family NmrA PF05368.13 GAX23424.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Zn_Tnp_IS1 PF03811.13 GAX23425.1 - 0.013 15.2 0.7 0.013 15.2 0.7 2.3 3 0 0 3 3 3 0 InsA N-terminal domain DZR PF12773.7 GAX23425.1 - 0.017 15.1 4.0 0.024 14.6 4.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 GAX23425.1 - 0.019 14.8 2.7 0.019 14.8 2.7 2.1 2 1 0 2 2 2 0 zinc-ribbon domain zf-LSD1 PF06943.12 GAX23425.1 - 0.023 14.6 0.3 0.044 13.6 0.3 1.5 1 0 0 1 1 1 0 LSD1 zinc finger Rubredoxin_2 PF18073.1 GAX23425.1 - 0.041 13.6 0.2 0.041 13.6 0.2 2.3 3 0 0 3 3 3 0 Rubredoxin metal binding domain HypA PF01155.19 GAX23425.1 - 0.052 13.6 0.7 0.061 13.3 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_10 PF10058.9 GAX23425.1 - 1.3 8.8 6.4 12 5.7 6.5 2.1 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ABC_tran PF00005.27 GAX23426.1 - 1.5e-39 135.7 2.5 8.3e-22 78.2 0.1 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAX23426.1 - 4.3e-22 78.6 0.6 4.7e-08 32.7 0.3 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX23426.1 - 6.6e-18 65.5 0.2 0.00039 20.3 0.0 4.6 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 GAX23426.1 - 2.2e-17 62.8 4.8 2.2e-17 62.8 4.8 3.0 3 0 0 3 3 3 1 ABC transporter ABC_tran_CTD PF16326.5 GAX23426.1 - 6.5e-11 42.3 6.3 6.5e-11 42.3 6.3 3.0 3 0 0 3 3 2 1 ABC transporter C-terminal domain AAA_29 PF13555.6 GAX23426.1 - 4.3e-09 36.0 0.3 0.0045 16.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 GAX23426.1 - 7.9e-07 29.3 0.8 0.0012 19.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 GAX23426.1 - 1.5e-06 28.9 14.9 0.003 18.1 3.7 3.8 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 GAX23426.1 - 8e-06 25.9 0.3 0.018 15.0 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAX23426.1 - 0.00012 22.1 0.0 0.016 15.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 GAX23426.1 - 0.00041 20.2 2.5 1.2 8.8 0.1 3.9 4 0 0 4 4 4 1 AAA ATPase domain AAA_16 PF13191.6 GAX23426.1 - 0.00044 20.7 2.8 1 9.7 0.2 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_27 PF13514.6 GAX23426.1 - 0.00072 19.2 2.0 0.57 9.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 GAX23426.1 - 0.00087 19.6 2.6 0.6 10.4 0.4 3.7 2 2 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GAX23426.1 - 0.0023 18.0 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 GAX23426.1 - 0.0059 15.6 0.5 0.29 10.1 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 GAX23426.1 - 0.0092 15.2 0.2 3 6.9 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 GAX23426.1 - 0.01 15.8 1.7 2.4 8.0 0.1 2.7 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 GAX23426.1 - 0.013 15.2 0.9 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 GAX23426.1 - 0.013 14.9 1.3 0.91 8.9 0.1 3.0 3 0 0 3 3 2 0 ADP-ribosylation factor family AAA_30 PF13604.6 GAX23426.1 - 0.014 15.1 5.4 1.1 8.9 0.1 3.0 2 2 0 2 2 2 0 AAA domain MutS_V PF00488.21 GAX23426.1 - 0.015 15.3 0.6 4.3 7.3 0.0 3.0 3 0 0 3 3 3 0 MutS domain V AAA_18 PF13238.6 GAX23426.1 - 0.018 15.6 0.3 3.4 8.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 GAX23426.1 - 0.039 14.2 1.1 1.9 8.7 0.2 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 GAX23426.1 - 0.04 14.3 0.1 17 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 GAX23426.1 - 0.07 12.7 1.5 5.3 6.6 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.7 GAX23426.1 - 0.085 11.8 0.1 4.8 6.0 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.29 GAX23426.1 - 0.095 13.1 0.1 11 6.5 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAX23426.1 - 0.2 11.1 0.8 6 6.3 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 GAX23426.1 - 0.26 10.8 1.7 12 5.4 0.1 3.5 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 GAX23426.1 - 0.27 10.5 9.1 0.74 9.1 1.1 3.5 3 1 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 GAX23426.1 - 0.37 10.7 3.5 15 5.4 0.1 3.2 3 0 0 3 3 3 0 NTPase AAA_17 PF13207.6 GAX23426.1 - 1.8 9.0 10.1 1.5 9.2 0.3 4.0 4 0 0 4 4 4 0 AAA domain Ploopntkinase3 PF18751.1 GAX23426.1 - 2.7 7.9 4.7 2.7 7.9 0.1 3.0 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 MIP-T3_C PF17749.1 GAX23426.1 - 3.2 7.7 8.0 0.45 10.5 0.2 2.8 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region FtsK_SpoIIIE PF01580.18 GAX23426.1 - 3.2 7.0 6.5 5.4 6.3 0.1 2.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family Fer2 PF00111.27 GAX23427.1 - 6.2e-08 32.5 0.5 7.6e-08 32.2 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ubiquitin PF00240.23 GAX23428.1 - 5.7e-34 115.7 0.4 7.4e-34 115.3 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GAX23428.1 - 7.1e-29 99.5 10.6 1.1e-28 98.9 10.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GAX23428.1 - 2.5e-16 59.3 0.7 3.3e-16 58.9 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX23428.1 - 1.3e-05 25.6 0.1 5.1e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX23428.1 - 0.0028 17.5 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX23428.1 - 0.0079 16.3 0.0 0.017 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAX23428.1 - 0.012 16.0 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 GAX23428.1 - 0.034 14.7 0.0 0.041 14.4 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX23428.1 - 0.062 13.4 1.7 6.6 6.8 0.0 2.4 3 0 0 3 3 3 0 Ubiquitin-like domain DUF2031 PF09592.10 GAX23429.1 - 0.056 13.0 0.5 0.12 11.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF2828 PF11443.8 GAX23429.1 - 0.088 10.9 6.1 0.11 10.5 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Transformer PF06495.11 GAX23429.1 - 0.82 9.7 19.2 1.2 9.2 19.2 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein RR_TM4-6 PF06459.12 GAX23429.1 - 0.98 9.2 12.1 1.6 8.5 12.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Use1 PF09753.9 GAX23429.1 - 3.8 7.2 19.3 8.5 6.0 19.3 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF4407 PF14362.6 GAX23429.1 - 7.8 5.8 8.9 11 5.2 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AA_kinase PF00696.28 GAX23430.1 - 8.2e-49 166.4 0.1 1.4e-48 165.6 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 GAX23430.1 - 4.5e-10 39.1 0.1 1.5e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 GAX23430.1 - 5.2e-05 22.9 0.4 0.0038 17.0 0.1 2.7 2 0 0 2 2 2 1 ACT domain CT_C_D PF02682.16 GAX23430.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Mito_carr PF00153.27 GAX23431.1 - 4.1e-43 145.2 2.9 2.2e-17 62.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DsbD_2 PF13386.6 GAX23431.1 - 0.013 15.4 1.2 1.4 8.8 0.1 2.5 2 1 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region ResB PF05140.14 GAX23431.1 - 0.074 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 ResB-like family BPD_transp_2 PF02653.16 GAX23431.1 - 1.1 8.3 6.9 1.2 8.2 0.1 2.5 3 0 0 3 3 3 0 Branched-chain amino acid transport system / permease component MPC PF03650.13 GAX23432.1 - 7.4e-43 145.2 1.4 3.7e-24 85.0 0.0 3.1 3 1 0 3 3 3 2 Mitochondrial pyruvate carriers TatD_DNase PF01026.21 GAX23433.1 - 5.2e-43 147.3 0.0 6.1e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase LMBR1 PF04791.16 GAX23434.1 - 4.4e-55 187.6 23.7 1.3e-36 126.6 0.3 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein Peptidase_S10 PF00450.22 GAX23435.1 - 4.7e-93 312.9 0.0 5.9e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase stn_TNFRSF12A PF12191.8 GAX23435.1 - 0.0065 16.7 0.2 0.017 15.3 0.2 1.7 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Herpes_gE PF02480.16 GAX23435.1 - 0.074 11.8 0.4 0.11 11.2 0.4 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3404 PF11884.8 GAX23435.1 - 0.21 10.8 3.1 2.7 7.1 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3404) RdRP PF05183.12 GAX23436.1 - 2.7e-26 92.4 0.0 2.1e-12 46.5 0.1 2.2 1 1 1 2 2 2 2 RNA dependent RNA polymerase Chromo PF00385.24 GAX23436.1 - 0.19 11.7 4.2 4.8 7.2 1.0 3.0 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain Steroid_dh PF02544.16 GAX23437.1 - 7e-43 146.2 1.1 7e-43 146.2 1.1 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 GAX23437.1 - 5.9e-05 22.7 1.2 0.00018 21.1 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 GAX23437.1 - 0.0041 17.5 2.9 0.0043 17.4 0.6 2.3 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1325 PF07039.11 GAX23440.1 - 3.1e-27 95.2 0.0 4.2e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain SAP30_Sin3_bdg PF13867.6 GAX23440.1 - 1.9e-07 31.3 0.0 3.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 HSF_DNA-bind PF00447.17 GAX23441.1 - 3.9e-14 53.0 0.0 6.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding AAA_16 PF13191.6 GAX23442.1 - 1.4e-24 87.4 0.3 6.1e-24 85.3 0.3 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX23442.1 - 0.00028 21.2 2.1 0.0035 17.6 0.4 2.8 2 1 0 2 2 2 1 AAA domain GvpD PF07088.11 GAX23442.1 - 0.015 14.0 0.1 0.027 13.1 0.1 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein ATPase PF06745.13 GAX23442.1 - 0.07 12.5 0.8 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 GAX23442.1 - 0.097 11.7 0.0 0.27 10.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 GAX23442.1 - 0.099 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Myosin_head PF00063.21 GAX23442.1 - 0.11 10.7 0.0 0.2 9.8 0.0 1.3 1 0 0 1 1 1 0 Myosin head (motor domain) ATPase_2 PF01637.18 GAX23442.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF1910 PF08928.10 GAX23442.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) PDZ_6 PF17820.1 GAX23443.1 - 3.8e-09 36.3 0.0 7.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX23443.1 - 1.2e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX23443.1 - 0.00048 20.4 0.1 0.00093 19.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_1 PF12812.7 GAX23443.1 - 0.0034 17.4 0.0 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 PDZ-like domain Tricorn_PDZ PF14685.6 GAX23443.1 - 0.016 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain DIM1 PF02966.16 GAX23444.1 - 6.3e-67 223.4 0.4 7.1e-67 223.2 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 GlcNAc-1_reg PF18440.1 GAX23444.1 - 0.06 13.6 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF3192 PF11399.8 GAX23444.1 - 0.11 12.4 0.2 0.15 12.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) SF3b10 PF07189.11 GAX23445.1 - 2.3e-33 114.1 0.0 3.3e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Ribosomal_S8 PF00410.19 GAX23446.1 - 0.00016 21.6 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L35Ae PF01247.18 GAX23447.1 - 5.2e-35 119.5 0.1 7.1e-35 119.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae CTP_synth_N PF06418.14 GAX23448.1 - 3.2e-119 397.1 0.0 4.1e-119 396.8 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 GAX23448.1 - 1.5e-50 171.7 0.0 2.1e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAX23448.1 - 0.00044 20.1 0.1 0.0021 17.9 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 CopG_antitoxin PF12441.8 GAX23448.1 - 0.012 16.1 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system CbiA PF01656.23 GAX23448.1 - 0.033 14.2 0.0 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 GAX23448.1 - 0.046 12.7 1.7 0.099 11.6 0.8 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LMBR1 PF04791.16 GAX23450.1 - 1.2e-55 189.4 19.5 8.7e-54 183.3 19.5 2.0 1 1 0 1 1 1 1 LMBR1-like membrane protein LRR19-TM PF15176.6 GAX23450.1 - 0.63 10.1 0.1 0.63 10.1 0.1 1.8 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain FAD_binding_2 PF00890.24 GAX23451.1 - 1.2e-72 245.3 3.3 1.7e-72 244.8 3.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAX23451.1 - 1e-06 28.7 0.4 3.2e-06 27.1 0.1 1.9 2 1 0 2 2 2 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 GAX23451.1 - 0.00013 21.3 0.2 0.14 11.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX23451.1 - 0.011 15.3 2.4 0.075 12.6 1.8 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GAX23451.1 - 0.068 12.2 0.2 0.65 9.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_1 PF00232.18 GAX23452.1 - 5.4e-157 522.8 0.6 2.4e-156 520.7 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 1 DUF2722 PF10846.8 GAX23452.1 - 1e-06 28.0 9.4 1.4e-06 27.5 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 GAX23452.1 - 0.0068 17.3 6.4 0.013 16.4 6.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) CLN3 PF02487.17 GAX23452.1 - 0.011 14.8 0.6 0.016 14.3 0.6 1.1 1 0 0 1 1 1 0 CLN3 protein DDHD PF02862.17 GAX23452.1 - 0.015 15.4 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 DDHD domain TssO PF17561.2 GAX23452.1 - 0.02 15.0 2.1 0.034 14.3 2.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO MecA PF05389.12 GAX23452.1 - 0.023 14.3 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) RskA PF10099.9 GAX23452.1 - 0.031 14.6 0.9 0.048 13.9 0.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FAM176 PF14851.6 GAX23452.1 - 0.036 13.7 0.3 0.068 12.8 0.3 1.3 1 0 0 1 1 1 0 FAM176 family eIF-3_zeta PF05091.12 GAX23452.1 - 0.044 12.8 7.0 0.064 12.2 7.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OATP PF03137.20 GAX23452.1 - 0.057 11.7 1.2 0.083 11.2 1.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SpoIIP PF07454.11 GAX23452.1 - 0.076 12.5 2.6 0.11 11.9 2.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 GAX23452.1 - 0.092 11.5 3.1 0.16 10.7 3.1 1.3 1 0 0 1 1 1 0 Presenilin EphA2_TM PF14575.6 GAX23452.1 - 0.094 13.6 0.6 0.21 12.5 0.6 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SHR3_chaperone PF08229.11 GAX23452.1 - 0.11 11.5 1.1 0.16 10.9 1.1 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 Folate_carrier PF01770.18 GAX23452.1 - 0.13 11.0 1.3 0.18 10.5 1.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier TMEM51 PF15345.6 GAX23452.1 - 0.15 11.9 7.7 0.24 11.2 7.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EPL1 PF10513.9 GAX23452.1 - 0.15 12.4 4.7 0.25 11.7 4.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like O-antigen_lig PF13425.6 GAX23452.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ABC2_membrane_2 PF12679.7 GAX23452.1 - 0.21 10.8 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein FHIPEP PF00771.20 GAX23452.1 - 0.27 9.7 2.9 0.38 9.1 2.9 1.1 1 0 0 1 1 1 0 FHIPEP family HemX PF04375.14 GAX23452.1 - 0.42 9.9 16.5 0.59 9.4 16.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2973 PF11189.8 GAX23452.1 - 0.45 10.6 1.8 1 9.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) EIIBC-GUT_N PF03612.14 GAX23452.1 - 0.49 10.1 3.4 0.77 9.5 3.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.8 GAX23452.1 - 0.53 9.9 32.5 5.5 6.5 34.7 1.4 2 0 0 2 2 1 0 Spt20 family CobT PF06213.12 GAX23452.1 - 0.59 9.5 10.5 1.2 8.4 10.0 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Ctr PF04145.15 GAX23452.1 - 0.7 10.5 3.8 1.2 9.7 3.8 1.5 1 1 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.13 GAX23452.1 - 0.78 9.7 25.0 1.1 9.2 25.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 GAX23452.1 - 0.84 9.6 13.2 1.3 9.0 13.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Asparaginase_2 PF01112.18 GAX23452.1 - 0.92 8.5 2.2 2.1 7.3 1.9 1.6 2 0 0 2 2 2 0 Asparaginase DivIC PF04977.15 GAX23452.1 - 1.1 9.1 15.0 2.3 8.1 15.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Jak1_Phl PF17887.1 GAX23452.1 - 1.3 9.0 9.9 2.1 8.3 9.9 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain MTABC_N PF16185.5 GAX23452.1 - 1.9 8.0 5.1 4.2 6.8 2.6 2.1 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region GRIP PF01465.20 GAX23454.1 - 1.9e-12 46.9 0.0 4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 GRIP domain IMUP PF15761.5 GAX23454.1 - 0.66 10.7 6.1 0.37 11.5 1.6 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein CaMKII_AD PF08332.10 GAX23455.1 - 5e-32 110.7 1.5 1.5e-15 57.5 0.5 2.1 1 1 1 2 2 2 2 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 GAX23455.1 - 9.9e-05 22.6 0.9 0.034 14.4 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like domain Alpha-amylase PF00128.24 GAX23455.1 - 0.0033 17.1 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain AMP-binding PF00501.28 GAX23456.1 - 1.1e-32 113.2 0.1 2e-32 112.3 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Ank_3 PF13606.6 GAX23456.1 - 4.9e-16 57.2 0.2 0.0038 17.6 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 GAX23456.1 - 4.9e-15 55.9 0.0 4.2e-07 30.5 0.0 3.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX23456.1 - 5.1e-14 52.4 2.8 1.5e-06 28.6 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX23456.1 - 3.8e-13 49.4 0.3 0.00028 21.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX23456.1 - 1.5e-10 41.1 2.3 0.035 14.6 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat AMP-binding_C PF13193.6 GAX23456.1 - 0.00059 20.8 0.1 0.0038 18.2 0.0 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain ESX-1_EspG PF14011.6 GAX23456.1 - 0.0033 17.1 0.0 0.0092 15.6 0.0 1.7 1 0 0 1 1 1 1 EspG family PP-binding PF00550.25 GAX23456.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site SAP PF02037.27 GAX23457.1 - 1.1e-07 31.4 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain TPR_2 PF07719.17 GAX23457.1 - 6.7e-05 22.7 10.2 0.015 15.4 0.7 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23457.1 - 0.00084 19.1 2.2 1.1 9.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1965 PF09248.10 GAX23457.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) TPR_8 PF13181.6 GAX23457.1 - 0.03 14.5 0.4 3.6 8.0 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Dicty_REP PF05086.12 GAX23457.1 - 0.58 8.1 6.3 0.82 7.6 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cpn60_TCP1 PF00118.24 GAX23458.1 - 7e-93 311.9 17.6 2.3e-92 310.2 17.6 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family MGAT2 PF05060.14 GAX23458.1 - 0.23 10.5 0.3 0.37 9.8 0.3 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) DUF373 PF04123.13 GAX23458.1 - 2.5 7.5 5.6 0.76 9.2 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF373) AAA PF00004.29 GAX23459.1 - 3.4e-32 111.6 0.1 2e-31 109.2 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX23459.1 - 2e-06 27.9 0.2 0.0031 17.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX23459.1 - 4.7e-06 27.1 0.2 3.2e-05 24.4 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_lid_3 PF17862.1 GAX23459.1 - 9.3e-06 25.4 0.1 2.6e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_24 PF13479.6 GAX23459.1 - 7.1e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAX23459.1 - 0.00015 21.5 0.0 0.0013 18.5 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAX23459.1 - 0.00019 21.8 0.0 0.0038 17.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 GAX23459.1 - 0.00025 20.4 0.0 0.0004 19.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 GAX23459.1 - 0.00058 20.1 0.1 0.0029 17.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX23459.1 - 0.0015 19.1 0.0 0.0074 16.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAX23459.1 - 0.0018 18.4 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAX23459.1 - 0.0024 18.0 0.0 0.01 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX23459.1 - 0.0048 17.4 0.0 0.012 16.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.17 GAX23459.1 - 0.0056 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 GAX23459.1 - 0.0057 16.6 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAX23459.1 - 0.0063 16.8 0.1 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAX23459.1 - 0.0092 15.4 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 GAX23459.1 - 0.0094 15.2 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 GAX23459.1 - 0.0098 15.5 0.1 0.066 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAX23459.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAX23459.1 - 0.031 14.7 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 GAX23459.1 - 0.036 13.2 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 GAX23459.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 GAX23459.1 - 0.047 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 GAX23459.1 - 0.096 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 GAX23459.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAX23459.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Hydin_ADK PF17213.3 GAX23459.1 - 1.3 9.3 4.9 1.6 8.9 1.8 2.5 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain PPK2 PF03976.14 GAX23460.1 - 6e-05 22.7 0.0 0.19 11.2 0.0 2.6 2 1 0 2 2 2 2 Polyphosphate kinase 2 (PPK2) Mito_carr PF00153.27 GAX23461.1 - 1.7e-34 117.6 7.6 2.3e-12 46.7 0.0 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein SNARE_assoc PF09335.11 GAX23462.1 - 8.6e-16 58.5 10.3 8.6e-16 58.5 10.3 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein Arteri_Gl PF00951.18 GAX23462.1 - 2.7 7.8 11.6 0.16 11.8 5.6 2.1 2 1 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF996 PF06195.13 GAX23462.1 - 3.7 7.8 13.9 1.2 9.5 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF996) Robl_LC7 PF03259.17 GAX23463.1 - 0.0021 17.8 0.2 0.0053 16.5 0.2 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain Profilin PF00235.19 GAX23463.1 - 0.023 15.0 0.0 0.042 14.1 0.0 1.5 1 1 0 1 1 1 0 Profilin Endonuclease_5 PF04493.14 GAX23464.1 - 1.9e-46 158.2 0.0 2e-45 154.9 0.0 2.0 1 1 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 GAX23464.1 - 0.0019 17.6 0.2 0.0051 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF99 LRR_8 PF13855.6 GAX23465.1 - 0.00015 21.4 6.9 0.00045 19.9 6.9 1.8 1 1 0 1 1 1 1 Leucine rich repeat LRRNT_2 PF08263.12 GAX23465.1 - 0.0025 18.1 2.1 0.009 16.3 2.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 GAX23465.1 - 0.0074 16.7 8.9 0.33 11.4 2.9 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) zf-RING_6 PF14835.6 GAX23465.1 - 0.17 11.7 2.9 0.36 10.7 2.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LRR_1 PF00560.33 GAX23465.1 - 1.1 10.1 4.1 30 5.7 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 GAX23466.1 - 9.5e-08 31.7 2.2 1.6e-07 31.0 2.2 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GAX23466.1 - 4.5e-06 26.9 4.7 0.00014 22.1 0.3 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX23466.1 - 0.0003 21.0 1.1 0.00057 20.1 1.1 1.4 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GAX23466.1 - 0.00096 19.4 0.1 3.8 8.4 0.1 3.7 3 0 0 3 3 3 1 Leucine Rich Repeat Nbl1_Borealin_N PF10444.9 GAX23467.1 - 1.8e-05 24.3 8.1 0.00011 21.8 4.3 2.3 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Borealin PF10512.9 GAX23467.1 - 0.002 18.1 4.6 0.0048 16.9 0.1 2.9 3 1 0 3 3 3 1 Cell division cycle-associated protein 8 DUF4509 PF14970.6 GAX23467.1 - 0.059 13.3 1.2 0.11 12.4 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) DUF3905 PF13045.6 GAX23467.1 - 0.12 12.4 0.1 0.52 10.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3905) LMBR1 PF04791.16 GAX23467.1 - 0.66 8.8 2.0 0.82 8.5 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein COPI_assoc PF08507.10 GAX23468.1 - 1.5e-09 38.0 1.2 1.9e-09 37.7 1.2 1.2 1 0 0 1 1 1 1 COPI associated protein DUF5336 PF17270.2 GAX23468.1 - 0.22 11.1 2.7 0.36 10.4 2.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF4282 PF14110.6 GAX23468.1 - 1.1 10.0 5.2 2.9 8.7 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) SPRY PF00622.28 GAX23470.1 - 2.8e-08 33.9 0.1 0.0011 19.1 0.0 2.7 3 0 0 3 3 3 2 SPRY domain IGPS PF00218.21 GAX23471.1 - 2.1e-67 227.0 0.2 5.9e-67 225.5 0.2 1.7 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 GAX23471.1 - 5e-43 147.1 0.2 1.7e-36 125.8 0.0 2.6 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.19 GAX23471.1 - 0.0068 16.2 0.0 0.37 10.5 0.0 2.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain DUF948 PF06103.11 GAX23471.1 - 0.18 12.1 4.8 3.6 7.9 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) NPL4 PF05021.15 GAX23472.1 - 3.2e-06 26.7 0.1 0.00045 19.7 0.1 2.8 2 1 0 2 2 2 2 NPL4 family PHD PF00628.29 GAX23473.1 - 0.0086 15.9 6.3 0.0086 15.9 6.3 1.8 2 0 0 2 2 2 1 PHD-finger POTRA_1 PF08478.10 GAX23473.1 - 0.12 12.7 0.7 1.2 9.5 0.4 2.4 2 0 0 2 2 2 0 POTRA domain, FtsQ-type 2OG-FeII_Oxy_3 PF13640.6 GAX23474.1 - 3.5e-05 24.6 0.0 6.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG6_N PF17675.1 GAX23474.1 - 0.022 15.3 1.6 0.035 14.7 0.7 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region PLAC8 PF04749.17 GAX23476.1 - 4.5e-13 50.0 9.4 8.7e-13 49.1 9.4 1.5 1 0 0 1 1 1 1 PLAC8 family LLC1 PF14945.6 GAX23476.1 - 0.11 13.1 1.4 0.42 11.2 0.3 2.4 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein EMG1 PF03587.14 GAX23477.1 - 4e-66 222.4 0.0 5.1e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase FAD_binding_3 PF01494.19 GAX23478.1 - 0.00032 20.1 2.7 1.6 7.9 0.6 3.4 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 GAX23478.1 - 0.03 13.9 4.4 0.041 13.5 1.3 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 GAX23478.1 - 0.096 11.7 0.0 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 GAX23478.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX23478.1 - 0.3 10.1 1.0 0.64 9.0 1.0 1.5 1 0 0 1 1 1 0 FAD binding domain UQ_con PF00179.26 GAX23479.1 - 7.9e-48 161.7 0.1 8.7e-48 161.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAX23479.1 - 0.017 15.4 0.2 0.023 15.0 0.2 1.4 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 GAX23479.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 TPR_2 PF07719.17 GAX23480.1 - 0.0063 16.5 0.1 0.0063 16.5 0.1 2.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23480.1 - 0.012 15.4 0.1 0.012 15.4 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23480.1 - 0.021 15.1 0.2 0.021 15.1 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PAS_9 PF13426.7 GAX23481.1 - 3.1e-06 27.4 0.1 4.4e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 PAS domain bZIP_1 PF00170.21 GAX23481.1 - 0.00012 22.1 6.2 0.00049 20.1 6.2 2.1 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.25 GAX23481.1 - 0.029 14.4 0.2 0.098 12.7 0.0 2.0 2 0 0 2 2 2 0 PAS fold bZIP_2 PF07716.15 GAX23481.1 - 0.11 12.6 8.3 0.36 10.9 8.3 2.0 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_2 PF07716.15 GAX23482.1 - 1.8e-14 53.6 26.3 2.7e-08 33.7 4.3 2.5 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 GAX23482.1 - 2.7e-11 43.4 19.9 2e-05 24.6 1.2 2.4 2 0 0 2 2 2 2 bZIP transcription factor Ino80_Iec3 PF14612.6 GAX23482.1 - 0.0014 19.4 1.4 0.0014 19.4 1.4 2.1 2 1 0 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling bZIP_Maf PF03131.17 GAX23482.1 - 0.12 12.9 18.8 2.1 8.9 9.1 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor CRT-like PF08627.10 GAX23483.1 - 8.6e-79 264.9 11.3 1e-40 139.8 2.4 2.0 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 GAX23483.1 - 9.1e-06 25.4 3.5 9.1e-06 25.4 3.5 1.9 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 GAX23483.1 - 0.00056 20.1 30.0 0.0066 16.6 7.9 3.8 3 1 0 3 3 3 3 EamA-like transporter family UAA PF08449.11 GAX23483.1 - 0.93 8.6 12.9 8.4 5.5 12.9 2.2 1 1 0 1 1 1 0 UAA transporter family Polysacc_deac_1 PF01522.21 GAX23484.1 - 2.9e-07 30.4 0.0 6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Toxin_12 PF07740.12 GAX23484.1 - 0.023 15.4 7.8 0.023 15.4 7.8 4.7 4 0 0 4 4 4 0 Ion channel inhibitory toxin HSP70 PF00012.20 GAX23485.1 - 1.6e-09 36.5 0.0 2.5e-05 22.7 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein Actin PF00022.19 GAX23485.1 - 0.042 12.5 0.0 0.1 11.2 0.0 1.6 1 1 0 1 1 1 0 Actin Ppx-GppA PF02541.16 GAX23485.1 - 0.086 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Med3 PF11593.8 GAX23487.1 - 0.45 9.6 4.6 0.49 9.5 4.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MDM10 PF12519.8 GAX23487.1 - 0.8 8.5 4.2 1.1 8.0 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF1275 PF06912.11 GAX23488.1 - 1.7e-14 54.2 16.6 2.9e-14 53.5 15.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) HCO3_cotransp PF00955.21 GAX23489.1 - 1.6e-88 297.8 12.4 1.7e-51 175.7 0.0 2.0 1 1 1 2 2 2 2 HCO3- transporter family Dioxygenase_C PF00775.21 GAX23490.1 - 2.3e-09 37.0 0.2 4.5e-07 29.5 0.2 2.4 1 1 0 1 1 1 1 Dioxygenase Tyr-DNA_phospho PF06087.12 GAX23491.1 - 3.4e-24 85.5 0.0 7.8e-24 84.3 0.0 1.5 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PfkB PF00294.24 GAX23492.1 - 4.9e-32 111.4 0.0 4.4e-24 85.3 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase AP_endonuc_2 PF01261.24 GAX23492.1 - 1.7e-17 63.6 0.1 4.4e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel TPR_6 PF13174.6 GAX23492.1 - 0.12 13.1 1.2 13 6.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat OmpH PF03938.14 GAX23492.1 - 0.22 11.9 5.3 0.26 11.6 0.5 2.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) PPR_2 PF13041.6 GAX23493.1 - 1.6e-09 37.8 0.3 0.0011 19.1 0.1 4.8 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 GAX23493.1 - 5.5e-07 29.6 0.0 0.066 13.3 0.0 3.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX23493.1 - 2.6e-05 23.7 1.1 0.097 12.0 0.0 3.5 2 2 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX23493.1 - 0.029 14.6 1.6 44 4.6 0.0 5.1 6 0 0 6 6 6 0 PPR repeat PPR_1 PF12854.7 GAX23493.1 - 0.09 12.5 6.6 14 5.5 0.1 4.2 4 0 0 4 4 4 0 PPR repeat SET PF00856.28 GAX23494.1 - 2.7e-12 47.4 0.0 4.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 SET domain AAA PF00004.29 GAX23495.1 - 5.4e-45 153.0 0.4 2.3e-44 151.0 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX23495.1 - 9.3e-09 35.4 0.1 3.1e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 GAX23495.1 - 1e-08 35.0 0.1 5.7e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 GAX23495.1 - 2.4e-08 34.3 0.1 8.8e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 GAX23495.1 - 1.2e-07 31.4 0.1 2.9e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX23495.1 - 9.6e-07 29.3 0.5 0.00036 20.9 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 GAX23495.1 - 4e-05 22.9 0.0 9.2e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAX23495.1 - 0.00011 22.4 2.4 0.011 16.0 0.6 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAX23495.1 - 0.00016 21.4 0.0 0.0006 19.6 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 GAX23495.1 - 0.00017 21.2 0.0 0.00067 19.2 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 GAX23495.1 - 0.00017 22.1 0.6 0.00078 20.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 GAX23495.1 - 0.00028 20.2 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain NTPase_1 PF03266.15 GAX23495.1 - 0.0012 18.8 0.3 0.086 12.7 0.0 3.0 3 0 0 3 3 3 1 NTPase Mg_chelatase PF01078.21 GAX23495.1 - 0.002 17.5 0.1 0.0046 16.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAX23495.1 - 0.0021 17.8 0.0 0.0044 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAX23495.1 - 0.0023 18.3 0.0 0.0057 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 GAX23495.1 - 0.0047 17.2 0.1 0.016 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 GAX23495.1 - 0.006 16.3 0.1 0.022 14.5 0.1 2.0 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 GAX23495.1 - 0.0067 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GAX23495.1 - 0.0069 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Parvo_NS1 PF01057.17 GAX23495.1 - 0.01 14.9 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 GAX23495.1 - 0.011 15.8 0.2 0.074 13.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAX23495.1 - 0.021 14.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 GAX23495.1 - 0.023 14.1 0.9 0.21 10.9 0.0 2.4 3 0 0 3 3 2 0 KaiC AAA_17 PF13207.6 GAX23495.1 - 0.03 14.8 0.1 0.075 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 GAX23495.1 - 0.052 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAX23495.1 - 0.053 13.4 0.3 0.18 11.7 0.0 2.1 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAX23495.1 - 0.085 12.3 0.0 1.5 8.2 0.0 2.3 1 1 0 2 2 2 0 Bacterial TniB protein AAA_11 PF13086.6 GAX23495.1 - 0.085 12.6 0.6 0.29 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX23495.1 - 0.09 12.3 0.4 0.3 10.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 GAX23495.1 - 0.095 12.6 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 GAX23495.1 - 0.098 12.5 0.1 2.2 8.1 0.0 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Torsin PF06309.11 GAX23495.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Guanylate_kin PF00625.21 GAX23495.1 - 0.19 11.4 1.7 2 8.1 0.0 3.0 2 1 1 4 4 3 0 Guanylate kinase CENP-Q PF13094.6 GAX23495.1 - 1.5 9.0 6.8 14 5.9 5.0 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit PX PF00787.24 GAX23496.1 - 5.3e-13 48.9 0.2 1.2e-12 47.8 0.2 1.6 2 0 0 2 2 2 1 PX domain OCD_Mu_crystall PF02423.15 GAX23497.1 - 5.7e-38 130.6 0.1 1.2e-37 129.6 0.1 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 GAX23497.1 - 2e-05 24.6 0.3 0.00023 21.2 0.3 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Brix PF04427.18 GAX23498.1 - 7.9e-30 104.4 0.1 1.1e-29 103.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain RNB PF00773.19 GAX23499.1 - 2.5e-89 299.8 0.0 3.6e-89 299.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAX23499.1 - 0.00011 22.2 0.0 0.00043 20.3 0.0 2.1 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) OB_RNB PF08206.11 GAX23499.1 - 0.0027 17.3 0.1 0.007 16.0 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain STPPase_N PF16891.5 GAX23499.1 - 0.0051 17.2 0.4 0.014 15.9 0.0 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain CSD2 PF17876.1 GAX23499.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Cold shock domain Dis3l2_C_term PF17877.1 GAX23499.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Peptidase_S8 PF00082.22 GAX23500.1 - 3.9e-46 157.7 0.2 6.1e-46 157.0 0.2 1.3 1 0 0 1 1 1 1 Subtilase family ShK PF01549.24 GAX23500.1 - 0.0087 16.6 11.0 0.033 14.7 1.3 2.7 2 0 0 2 2 2 2 ShK domain-like Ribosomal_L31 PF01197.18 GAX23500.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L31 Actin PF00022.19 GAX23501.1 - 5.1e-67 226.3 0.0 1e-66 225.2 0.0 1.5 1 1 0 1 1 1 1 Actin MCM3AP_GANP PF16769.5 GAX23501.1 - 0.36 9.0 2.9 0.48 8.6 2.9 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Arm PF00514.23 GAX23502.1 - 3.3e-14 52.4 20.3 1.1e-05 25.3 0.3 7.5 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 GAX23502.1 - 0.0039 17.2 3.9 2.1 8.4 0.0 3.7 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain KAP PF05804.12 GAX23502.1 - 0.04 12.1 4.4 0.061 11.5 0.8 2.0 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) Arm_2 PF04826.13 GAX23502.1 - 0.058 12.8 0.2 0.058 12.8 0.2 3.3 1 1 3 4 4 4 0 Armadillo-like OCRL_clath_bd PF16726.5 GAX23502.1 - 0.071 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Inositol polyphosphate 5-phosphatase clathrin binding domain HEAT_EZ PF13513.6 GAX23502.1 - 0.2 12.2 3.0 56 4.4 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat PLAC8 PF04749.17 GAX23504.1 - 9.4e-15 55.4 8.7 1.4e-14 54.8 8.7 1.3 1 0 0 1 1 1 1 PLAC8 family DUF5337 PF17272.2 GAX23504.1 - 0.21 11.5 0.3 0.47 10.3 0.2 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5337) MA3 PF02847.17 GAX23505.1 - 4.3e-23 81.5 0.1 1.2e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 GAX23505.1 - 1.1e-15 57.9 0.0 1.1e-14 54.6 0.0 2.3 2 0 0 2 2 2 1 MIF4G domain CENP-B_dimeris PF09026.10 GAX23505.1 - 0.061 13.7 9.0 0.21 12.0 9.0 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SPX PF03105.19 GAX23505.1 - 0.097 12.6 24.1 0.42 10.5 22.1 2.2 2 0 0 2 2 2 0 SPX domain Arm_2 PF04826.13 GAX23506.1 - 0.0075 15.8 0.4 0.0075 15.8 0.4 1.9 2 1 0 3 3 3 1 Armadillo-like Ank_2 PF12796.7 GAX23507.1 - 2e-10 41.1 0.0 0.86 10.2 0.0 6.1 3 3 3 6 6 6 3 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 GAX23507.1 - 5.5e-09 35.8 9.0 9.7e-09 35.0 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX23507.1 - 2.7e-08 33.6 9.9 5e-08 32.7 9.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank_5 PF13857.6 GAX23507.1 - 4.1e-08 33.3 0.1 0.019 15.3 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX23507.1 - 1.9e-06 28.1 4.9 6.3 7.4 0.0 6.9 8 0 0 8 8 8 2 Ankyrin repeat Ank_3 PF13606.6 GAX23507.1 - 2.1e-06 27.6 2.5 13 6.8 0.0 7.2 7 0 0 7 7 7 1 Ankyrin repeat zf-RING_2 PF13639.6 GAX23507.1 - 0.0057 17.0 9.9 0.012 15.9 9.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAX23507.1 - 0.16 12.0 7.8 0.34 10.9 7.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RMI1_N PF08585.12 GAX23508.1 - 8.5e-20 71.4 2.5 2.8e-19 69.8 0.4 2.6 2 1 0 2 2 2 1 RecQ mediated genome instability protein B12D PF06522.11 GAX23509.1 - 7.7e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GCV_T PF01571.21 GAX23510.1 - 1.3e-08 34.5 0.0 2.1e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain Mito_carr PF00153.27 GAX23511.1 - 2.1e-34 117.3 2.3 3.7e-14 52.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.11 GAX23512.1 - 1.7e-10 40.5 0.0 2.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PspA_IM30 PF04012.12 GAX23513.1 - 8.1e-45 153.1 25.4 1.3e-44 152.4 25.4 1.3 1 0 0 1 1 1 1 PspA/IM30 family Spc7 PF08317.11 GAX23513.1 - 0.0071 15.3 28.5 0.35 9.7 3.3 2.8 1 1 1 2 2 2 2 Spc7 kinetochore protein Pox_F11 PF04943.12 GAX23513.1 - 0.03 13.4 4.7 0.036 13.2 4.7 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein NPV_P10 PF05531.12 GAX23513.1 - 0.099 13.1 10.3 10 6.7 0.0 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 GAX23513.1 - 0.26 11.5 14.9 1.2 9.3 7.8 3.3 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PYC_OADA PF02436.18 GAX23513.1 - 1.8 8.2 6.1 0.38 10.5 0.7 2.4 1 1 1 2 2 2 0 Conserved carboxylase domain Lebercilin PF15619.6 GAX23513.1 - 2.7 7.6 24.2 0.097 12.3 15.6 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cob_adeno_trans PF01923.18 GAX23513.1 - 3.7 7.7 11.6 21 5.2 5.7 3.1 1 1 0 2 2 2 0 Cobalamin adenosyltransferase UPF0242 PF06785.11 GAX23513.1 - 7 6.7 20.7 0.13 12.4 10.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_hydro_4C PF11975.8 GAX23514.1 - 0.061 13.4 0.1 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Radical_SAM PF04055.21 GAX23515.1 - 4.4e-29 102.0 0.0 1.1e-28 100.7 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 GAX23515.1 - 3e-27 94.5 0.4 9.6e-27 92.9 0.2 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 GAX23515.1 - 5.3e-06 26.3 0.2 5.4e-05 23.1 0.2 2.3 1 1 0 1 1 1 1 TRAM domain DUF2326 PF10088.9 GAX23515.1 - 0.074 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) GlnD_UR_UTase PF08335.11 GAX23516.1 - 0.012 15.7 1.5 0.02 15.0 1.5 1.5 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase HMGL-like PF00682.19 GAX23516.1 - 0.029 13.9 0.4 0.037 13.6 0.4 1.3 1 0 0 1 1 1 0 HMGL-like CENP-C_mid PF15620.6 GAX23516.1 - 0.73 9.8 7.9 0.11 12.5 3.2 1.8 1 1 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region PDEase_I PF00233.19 GAX23517.1 - 4.8e-33 114.9 4.7 5.3e-33 114.7 3.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 GAX23517.1 - 1.6e-19 70.2 0.1 3.1e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.13 GAX23517.1 - 0.0022 17.9 0.0 0.012 15.5 0.0 2.2 1 1 0 1 1 1 1 CHASE domain MHC2-interact PF09307.10 GAX23517.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting MutS_V PF00488.21 GAX23518.1 - 5.8e-78 261.3 0.4 1.6e-77 259.8 0.4 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 GAX23518.1 - 1.4e-19 71.1 1.6 3.3e-19 69.9 1.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAX23518.1 - 8.5e-05 22.8 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 GAX23518.1 - 0.011 15.3 0.1 0.047 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX23518.1 - 0.018 15.3 0.0 0.067 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX23518.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX23518.1 - 0.83 10.1 0.0 0.83 10.1 0.0 2.2 2 1 1 3 3 3 0 AAA domain PDEase_I PF00233.19 GAX23519.1 - 8.3e-34 117.3 2.2 2e-33 116.1 2.2 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 GAX23519.1 - 2.1e-31 109.0 0.0 3.7e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Carbpep_Y_N PF05388.11 GAX23519.1 - 0.063 13.8 0.1 0.29 11.7 0.1 2.2 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide MORN PF02493.20 GAX23520.1 - 5e-26 89.0 82.9 6.6e-05 22.6 0.9 12.3 12 0 0 12 12 12 11 MORN repeat Glycos_transf_2 PF00535.26 GAX23521.1 - 1.9e-31 109.2 0.0 2.3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX23521.1 - 1.9e-16 60.7 0.0 2.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAX23521.1 - 2.4e-05 23.9 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 GAX23521.1 - 0.0048 16.4 0.0 0.006 16.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 GAX23521.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 G-patch PF01585.23 GAX23522.1 - 9e-06 25.5 1.2 2.5e-05 24.1 1.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAX23522.1 - 0.0015 18.6 1.7 0.0015 18.6 1.7 2.1 2 0 0 2 2 2 1 G-patch domain zf-C2H2_4 PF13894.6 GAX23522.1 - 0.0057 17.4 0.2 0.011 16.6 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAX23522.1 - 0.035 14.4 0.2 0.055 13.8 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAX23522.1 - 0.041 14.2 0.1 0.087 13.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 GAX23522.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 GAX23522.1 - 6.7 6.6 9.3 0.31 10.9 1.6 2.8 3 1 0 3 3 3 0 Rad50 zinc hook motif DnaJ PF00226.31 GAX23523.1 - 1.9e-22 79.2 2.0 3.5e-22 78.3 2.0 1.5 1 0 0 1 1 1 1 DnaJ domain MPM1 PF17234.2 GAX23523.1 - 0.0031 17.8 0.4 0.0031 17.8 0.4 2.3 2 0 0 2 2 2 1 Mitochondrial peculiar membrane protein 1 Rod_C PF10493.9 GAX23523.1 - 0.42 9.0 1.2 0.86 7.9 0.4 1.7 2 0 0 2 2 2 0 Rough deal protein C-terminal region FA_desaturase PF00487.24 GAX23524.1 - 3.5e-28 99.1 7.5 5.1e-28 98.6 7.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 GAX23524.1 - 1.8e-21 75.3 0.4 5.6e-21 73.7 0.1 1.9 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Ribosomal_TL5_C PF14693.6 GAX23525.1 - 0.042 14.2 0.1 0.085 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain Cyclin_N PF00134.23 GAX23526.1 - 6.3e-14 51.8 0.2 1.3e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cren7 PF11520.8 GAX23526.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin protein Cren7 Kdo PF06293.14 GAX23527.1 - 4.8e-11 42.4 0.0 6.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAX23527.1 - 2.9e-08 33.4 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 GAX23527.1 - 4.2e-08 33.0 0.1 8.7e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 GAX23527.1 - 1.6e-07 31.5 0.3 0.0036 17.3 0.1 2.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GAX23527.1 - 1.4e-05 24.5 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2939 PF11159.8 GAX23527.1 - 0.00094 19.5 0.1 0.0037 17.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2939) EcKinase PF02958.20 GAX23527.1 - 0.027 13.8 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_fungal PF17667.1 GAX23527.1 - 0.047 12.5 0.1 0.066 12.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase STAG PF08514.11 GAX23528.1 - 0.075 12.9 0.8 0.14 12.0 0.8 1.4 1 0 0 1 1 1 0 STAG domain KBP_C PF12309.8 GAX23528.1 - 0.11 12.1 0.5 0.17 11.4 0.5 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal BUD22 PF09073.10 GAX23528.1 - 1.8 7.8 15.9 2.7 7.2 15.9 1.2 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 GAX23529.1 - 0.0055 15.7 1.1 0.0095 15.0 1.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) CPT_N PF16484.5 GAX23529.1 - 0.2 11.7 0.0 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus SAPS PF04499.15 GAX23529.1 - 1.5 7.5 11.0 2.4 6.9 11.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein mTERF PF02536.14 GAX23530.1 - 0.0079 15.2 0.0 0.072 12.0 0.0 2.2 2 0 0 2 2 2 1 mTERF DUF4502 PF14950.6 GAX23530.1 - 0.29 10.5 4.3 0.39 10.1 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Sororin PF09666.10 GAX23532.1 - 3.2 8.0 5.8 7.6 6.8 5.8 1.9 1 1 0 1 1 1 0 Sororin protein Cyclin_N PF00134.23 GAX23533.1 - 3.5e-12 46.2 0.0 6.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX23533.1 - 7.2e-06 26.1 0.0 8.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain FXR_C1 PF16096.5 GAX23533.1 - 1.2 9.4 6.6 0.13 12.5 2.1 1.6 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Abhydrolase_6 PF12697.7 GAX23534.1 - 7.6e-13 49.6 4.6 1e-12 49.1 4.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX23534.1 - 8.9e-10 38.2 0.0 1.8e-08 34.0 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX23534.1 - 1.1e-06 28.5 0.1 0.065 12.9 0.0 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 GAX23534.1 - 0.018 14.7 0.0 0.17 11.5 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 GAX23534.1 - 0.045 13.9 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein Thioesterase PF00975.20 GAX23534.1 - 0.12 12.4 0.0 0.63 10.1 0.0 1.9 1 1 0 1 1 1 0 Thioesterase domain STI1 PF17830.1 GAX23535.1 - 6.9e-08 32.3 5.2 0.00091 19.1 2.3 2.8 2 1 1 3 3 3 2 STI1 domain SAP PF02037.27 GAX23535.1 - 5.7e-06 26.0 2.4 0.12 12.2 0.4 3.9 4 0 0 4 4 4 2 SAP domain Armet PF10208.9 GAX23535.1 - 0.00017 21.6 0.1 0.12 12.3 0.1 2.2 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding SR-25 PF10500.9 GAX23535.1 - 0.0013 18.4 8.3 0.002 17.8 8.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Snf7 PF03357.21 GAX23535.1 - 0.0054 16.4 2.5 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Snf7 HeH PF12949.7 GAX23535.1 - 0.048 13.4 0.1 11 5.9 0.0 2.6 3 0 0 3 3 3 0 HeH/LEM domain Rho_N PF07498.12 GAX23535.1 - 0.072 13.0 2.9 0.56 10.2 0.1 2.6 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain GerD PF17898.1 GAX23535.1 - 0.082 12.9 0.4 0.082 12.9 0.4 2.8 3 1 0 3 3 3 0 Spore germination GerD central core domain BCNT PF07572.12 GAX23535.1 - 0.4 10.8 3.9 2.3 8.3 1.0 2.8 3 0 0 3 3 3 0 Bucentaur or craniofacial development GA-like PF17573.2 GAX23535.1 - 0.65 10.0 4.0 27 4.8 1.1 3.0 2 1 0 2 2 2 0 GA-like domain WDCP PF15390.6 GAX23535.1 - 0.9 7.8 4.7 1.2 7.4 4.7 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family CENP-R PF06729.12 GAX23535.1 - 1 9.3 10.9 3 7.8 9.4 2.3 1 1 1 2 2 2 0 Kinetochore component, CENP-R DER1 PF04511.15 GAX23536.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Der1-like family HPP PF04982.13 GAX23536.1 - 0.086 13.0 0.2 0.086 13.0 0.2 2.2 3 0 0 3 3 3 0 HPP family PP2C PF00481.21 GAX23537.1 - 4.6e-56 190.3 0.0 1e-55 189.2 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 GAX23537.1 - 6.2e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain PP2C_2 PF13672.6 GAX23537.1 - 7.8e-06 25.7 0.1 3.6e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Yop-YscD_cpl PF16697.5 GAX23537.1 - 0.00017 21.8 0.0 0.00085 19.6 0.0 2.2 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF543 PF04418.12 GAX23538.1 - 1.2e-13 50.8 1.1 1.4e-13 50.6 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ApoO PF09769.9 GAX23538.1 - 0.2 11.6 1.1 0.22 11.5 1.1 1.2 1 0 0 1 1 1 0 Apolipoprotein O CLASP_N PF12348.8 GAX23539.1 - 1.7e-13 50.7 0.0 2.7e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 GAX23539.1 - 0.002 18.2 2.6 1.2 9.6 0.0 3.8 4 0 0 4 4 4 2 HEAT repeat DoxX PF07681.12 GAX23540.1 - 1e-12 48.4 4.7 1e-12 48.4 4.7 1.7 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 GAX23540.1 - 0.0002 21.3 0.2 0.001 19.0 0.2 1.9 1 1 0 1 1 1 1 TQO small subunit DoxD DoxX_2 PF13564.6 GAX23540.1 - 0.0019 18.2 0.6 0.0019 18.2 0.6 1.8 2 0 0 2 2 2 1 DoxX-like family Rhomboid PF01694.22 GAX23542.1 - 0.0027 17.7 1.2 0.0027 17.7 1.2 2.3 3 0 0 3 3 3 1 Rhomboid family Cad PF03596.13 GAX23542.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Cadmium resistance transporter Peptidase_U4 PF03419.13 GAX23542.1 - 0.18 11.1 2.1 0.76 9.0 0.5 2.1 1 1 1 2 2 2 0 Sporulation factor SpoIIGA NST1 PF13945.6 GAX23543.1 - 0.11 12.6 4.0 0.12 12.5 3.3 1.4 1 1 0 1 1 1 0 Salt tolerance down-regulator THOC2_N PF16134.5 GAX23543.1 - 0.66 8.5 2.8 0.79 8.3 2.8 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus TSGP1 PF07771.11 GAX23543.1 - 8.5 6.6 8.2 0.99 9.6 4.0 1.6 2 0 0 2 2 2 0 Tick salivary peptide group 1 HCO3_cotransp PF00955.21 GAX23544.1 - 1.9e-86 290.9 12.1 6.6e-52 177.0 0.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family Fumerase_C PF05683.12 GAX23545.1 - 1.1e-85 286.2 0.0 2.2e-85 285.1 0.0 1.6 2 0 0 2 2 2 1 Fumarase C-terminus Fumerase PF05681.14 GAX23545.1 - 1e-84 284.2 0.0 1.4e-84 283.7 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) RuvX PF03652.15 GAX23546.1 - 0.079 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction resolvase CDC50 PF03381.15 GAX23547.1 - 1.6e-66 224.7 0.1 2.1e-66 224.3 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 GAX23547.1 - 0.15 12.1 0.9 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF998 PF06197.13 GAX23548.1 - 0.22 11.1 20.6 0.014 15.0 4.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF998) Amino_oxidase PF01593.24 GAX23549.1 - 3.9e-20 72.6 0.0 8e-20 71.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX23549.1 - 1.4e-13 50.9 0.0 3.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX23549.1 - 9.2e-10 38.2 0.2 4e-06 26.2 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX23549.1 - 9.8e-06 25.4 2.0 0.00016 21.4 1.9 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAX23549.1 - 1e-05 24.9 0.1 2.2e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAX23549.1 - 0.00049 19.2 0.6 0.0047 16.0 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAX23549.1 - 0.00052 19.4 0.0 0.00082 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.18 GAX23549.1 - 0.0016 17.0 0.0 0.33 9.4 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor HI0933_like PF03486.14 GAX23549.1 - 0.0021 16.8 0.1 0.057 12.1 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAX23549.1 - 0.0025 17.1 0.0 0.0079 15.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX23549.1 - 0.007 15.7 0.1 0.033 13.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX23549.1 - 0.02 15.4 0.4 0.12 13.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX23549.1 - 0.02 14.2 0.6 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAX23549.1 - 0.037 13.1 0.5 3.5 6.6 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A MCRA PF06100.11 GAX23549.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family DUF305 PF03713.13 GAX23550.1 - 2.9e-09 37.2 4.1 1.5e-05 25.2 0.9 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF305) Bestrophin PF01062.21 GAX23551.1 - 7e-37 127.4 0.0 9.2e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel F-box PF00646.33 GAX23552.1 - 0.03 14.2 3.1 1.9 8.5 0.1 2.9 2 0 0 2 2 2 0 F-box domain A2L_zn_ribbon PF08792.10 GAX23552.1 - 0.67 9.7 0.0 0.67 9.7 0.0 3.9 3 1 0 3 3 3 0 A2L zinc ribbon domain adh_short PF00106.25 GAX23553.1 - 6e-33 113.9 0.5 7.7e-33 113.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX23553.1 - 3.2e-23 82.5 0.2 4.4e-23 82.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX23553.1 - 0.012 15.5 1.5 0.028 14.3 1.5 1.6 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 GAX23553.1 - 0.048 12.8 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAX23553.1 - 0.05 13.1 0.3 0.07 12.6 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 GAX23554.1 - 0.0015 19.1 0.0 0.026 15.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX23554.1 - 0.0093 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PBP1_TM PF14812.6 GAX23554.1 - 0.043 14.2 12.2 2.4 8.6 0.0 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RelA_SpoT PF04607.17 GAX23555.1 - 3e-24 85.5 0.0 5.8e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 GAX23555.1 - 8.5e-13 48.3 2.4 2e-12 47.1 0.4 2.6 2 1 1 3 3 3 1 HD domain PseudoU_synth_1 PF01416.20 GAX23556.1 - 3.3e-14 53.3 0.1 4.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ribosomal_L22 PF00237.19 GAX23557.1 - 2.8e-21 75.7 0.0 5.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GPP34 PF05719.11 GAX23557.1 - 0.016 15.3 1.2 0.016 15.2 0.0 1.6 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) DUF515 PF04415.12 GAX23557.1 - 0.3 9.4 2.7 0.4 9.0 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1995 PF09353.10 GAX23561.1 - 7.6e-39 133.8 0.1 8.9e-39 133.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Aminotran_1_2 PF00155.21 GAX23562.1 - 2.1e-47 162.0 0.0 2.7e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1071 PF06378.11 GAX23562.1 - 0.0053 16.3 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1071) Aminotran_3 PF00202.21 GAX23562.1 - 0.19 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Glyco_trans_4_4 PF13579.6 GAX23562.1 - 0.31 11.5 3.2 13 6.2 3.2 2.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Acetyltransf_1 PF00583.25 GAX23563.1 - 2.8e-17 63.0 0.0 3.6e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX23563.1 - 7.4e-12 45.3 0.1 9.1e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX23563.1 - 2.4e-10 40.7 0.1 3.4e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX23563.1 - 3.1e-06 27.3 0.0 4.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX23563.1 - 0.00026 20.9 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 GAX23563.1 - 0.00056 19.6 0.0 0.00074 19.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX23563.1 - 0.00085 19.4 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 GAX23563.1 - 0.02 14.6 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ SASA PF03629.18 GAX23564.1 - 4.3e-15 56.0 0.0 5.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase NCE101 PF11654.8 GAX23564.1 - 0.061 13.0 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 Nop PF01798.18 GAX23565.1 - 4.7e-83 278.2 0.4 4.7e-83 278.2 0.4 1.9 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAX23565.1 - 1.4e-18 67.1 0.9 1.4e-18 67.1 0.9 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SAPS PF04499.15 GAX23565.1 - 5.5 5.7 10.8 9.3 4.9 10.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pro_isomerase PF00160.21 GAX23566.1 - 9.1e-14 52.0 0.0 1.4e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HAUS2 PF15003.6 GAX23566.1 - 0.04 13.6 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 ABC_tran_CTD PF16326.5 GAX23566.1 - 0.05 13.9 0.6 0.092 13.0 0.6 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain HemX PF04375.14 GAX23566.1 - 0.054 12.8 0.4 0.079 12.2 0.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase YvfG PF09628.10 GAX23566.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 YvfG protein Response_reg PF00072.24 GAX23567.1 - 0.015 15.5 0.0 0.031 14.4 0.0 1.6 1 1 0 1 1 1 0 Response regulator receiver domain Fib_alpha PF08702.10 GAX23568.1 - 0.0019 18.4 7.5 0.0019 18.4 7.5 1.7 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF724 PF05266.14 GAX23568.1 - 0.089 12.6 2.0 0.2 11.5 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 GAX23568.1 - 0.12 12.6 1.7 0.27 11.5 0.4 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Csm1_N PF18504.1 GAX23568.1 - 0.65 10.4 7.1 1.7 9.0 7.1 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 GAX23568.1 - 2.4 8.0 9.2 0.41 10.4 5.2 1.9 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 GAX23568.1 - 2.9 8.6 11.0 1.3 9.6 5.5 3.0 2 1 2 4 4 4 0 SlyX MAT1 PF06391.13 GAX23569.1 - 1.1e-27 97.3 15.4 1.5e-27 96.8 15.4 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.25 GAX23569.1 - 3.6e-07 29.9 5.2 8.6e-07 28.7 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX23569.1 - 3.1e-06 27.4 5.2 6.1e-06 26.5 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX23569.1 - 9.1e-06 25.6 2.7 2.1e-05 24.5 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAX23569.1 - 1.5e-05 25.1 2.5 1.5e-05 25.1 2.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAX23569.1 - 5.8e-05 22.8 9.5 0.00024 20.9 9.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX23569.1 - 0.0001 22.2 8.9 0.00036 20.4 8.9 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX23569.1 - 0.00018 21.3 7.7 0.00073 19.3 7.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX23569.1 - 0.0005 20.3 4.0 0.0012 19.1 4.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain UvrD-helicase PF00580.21 GAX23569.1 - 0.0012 18.5 2.5 0.0015 18.1 2.5 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain EFG_C PF00679.24 GAX23569.1 - 0.0028 17.6 0.0 0.0064 16.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Prok-RING_4 PF14447.6 GAX23569.1 - 0.0033 17.2 5.4 0.01 15.7 5.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 GAX23569.1 - 0.016 15.3 5.2 0.04 14.0 5.2 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 GAX23569.1 - 0.052 13.4 7.8 0.042 13.7 4.8 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GAX23569.1 - 0.069 13.0 3.3 0.19 11.6 3.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4148 PF13663.6 GAX23569.1 - 0.16 12.2 1.5 0.32 11.2 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) FHIPEP PF00771.20 GAX23569.1 - 0.22 9.9 3.7 0.28 9.6 3.7 1.1 1 0 0 1 1 1 0 FHIPEP family zf-FPG_IleRS PF06827.14 GAX23569.1 - 0.68 9.8 0.1 0.68 9.8 0.1 3.9 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Acetone_carb_G PF08882.11 GAX23569.1 - 0.89 9.7 8.4 2.9 8.1 0.2 3.8 1 1 2 4 4 4 0 Acetone carboxylase gamma subunit TSP_3 PF02412.18 GAX23570.1 - 0.00029 20.4 121.8 0.012 15.3 6.9 13.1 5 2 7 12 12 12 9 Thrombospondin type 3 repeat Sulfotransfer_3 PF13469.6 GAX23571.1 - 0.00094 19.6 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Ribosomal_L1 PF00687.21 GAX23572.1 - 6.1e-43 146.9 1.9 7.6e-43 146.6 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pkinase PF00069.25 GAX23573.1 - 8.1e-65 218.8 0.0 9.1e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23573.1 - 2.6e-26 92.5 0.0 3.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX23573.1 - 3e-05 23.5 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAX23573.1 - 0.008 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX23573.1 - 0.054 12.4 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAX23573.1 - 0.059 12.7 0.1 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2012 PF09430.10 GAX23574.1 - 3.6e-24 85.2 0.0 5.2e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 GAX23574.1 - 0.0027 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 GAX23574.1 - 0.15 12.3 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain NifU PF01106.17 GAX23575.1 - 2.1e-23 82.2 0.9 1.9e-21 76.0 0.1 2.4 2 0 0 2 2 2 2 NifU-like domain Pkinase PF00069.25 GAX23577.1 - 5.5e-39 134.1 0.0 9.7e-39 133.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23577.1 - 1.6e-18 66.9 0.0 9.6e-17 61.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX23577.1 - 1.6e-05 24.9 0.0 4.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX23577.1 - 0.00016 20.6 0.0 0.00022 20.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX23577.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAX23577.1 - 0.006 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 GAX23577.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cofilin_ADF PF00241.20 GAX23578.1 - 4.1e-07 29.8 0.0 5.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Thymidylat_synt PF00303.19 GAX23579.1 - 7.2e-119 395.8 0.0 9.8e-119 395.4 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 GAX23579.1 - 2.3e-46 157.4 0.0 6.7e-46 155.9 0.0 1.7 2 0 0 2 2 2 1 Dihydrofolate reductase DEAD PF00270.29 GAX23581.1 - 2.1e-34 118.8 0.0 3.4e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX23581.1 - 1.8e-25 89.4 0.3 2.2e-24 86.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX23581.1 - 3.2e-06 27.2 0.1 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TPR_19 PF14559.6 GAX23582.1 - 1.4e-07 31.9 1.9 5.2 7.6 0.0 6.2 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX23582.1 - 1.1e-06 28.9 21.7 0.0068 17.1 0.6 8.8 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23582.1 - 0.00027 21.2 13.6 0.095 13.0 0.1 5.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX23582.1 - 0.057 14.1 8.1 0.19 12.4 0.3 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX23582.1 - 0.085 12.6 0.0 26 4.6 0.0 3.6 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.17 GAX23582.1 - 0.88 9.8 14.9 0.24 11.6 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23582.1 - 2 8.8 7.2 3.7 8.0 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PfkB PF00294.24 GAX23585.1 - 1.4e-28 100.1 0.2 2.1e-16 60.1 0.0 3.1 3 0 0 3 3 3 3 pfkB family carbohydrate kinase Phage_GP20 PF06810.11 GAX23585.1 - 0.0039 17.0 0.9 0.011 15.5 0.9 1.7 1 0 0 1 1 1 1 Phage minor structural protein GP20 Phage_term_smal PF05944.12 GAX23585.1 - 0.032 14.2 0.1 0.079 12.9 0.1 1.6 1 0 0 1 1 1 0 Phage small terminase subunit HGTP_anticodon PF03129.20 GAX23585.1 - 0.059 13.5 0.3 4.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Anticodon binding domain Dus PF01207.17 GAX23586.1 - 3e-51 174.4 0.0 5.5e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Symplekin_C PF12295.8 GAX23586.1 - 3e-37 128.5 0.0 6.8e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 GAX23586.1 - 9.8e-13 48.3 0.0 4.1e-10 39.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3453) zf-CCCH PF00642.24 GAX23586.1 - 0.00063 19.6 10.0 0.039 13.9 0.3 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAX23586.1 - 0.00082 19.4 10.0 0.038 14.1 0.7 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 GAX23586.1 - 0.3 11.8 0.0 0.3 11.8 0.0 2.4 3 0 0 3 3 3 0 Torus domain UQ_con PF00179.26 GAX23587.1 - 1e-18 67.4 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aldo_ket_red PF00248.21 GAX23588.1 - 8.1e-63 212.3 0.0 1.1e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M16 PF00675.20 GAX23589.1 - 0.0012 18.8 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX23589.1 - 0.031 14.3 0.0 0.091 12.8 0.0 1.7 1 1 1 2 2 2 0 Peptidase M16 inactive domain Inhibitor_I53 PF11714.8 GAX23589.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin HORMA PF02301.18 GAX23590.1 - 1.2e-20 74.0 0.1 1.5e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 HORMA domain NifU_N PF01592.16 GAX23591.1 - 1.6e-54 183.5 0.1 2e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DNA_pol_B PF00136.21 GAX23592.1 - 2.4e-139 465.0 0.6 3.1e-139 464.6 0.6 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAX23592.1 - 5.3e-70 236.2 0.0 7.8e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAX23592.1 - 6.6e-09 36.1 0.9 1.6e-08 34.9 0.9 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 GAX23592.1 - 4.1e-05 22.7 4.1 0.0025 16.8 0.3 2.4 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 GAX23592.1 - 0.038 13.7 0.1 0.08 12.7 0.1 1.6 1 0 0 1 1 1 0 3'-5' exonuclease Lung_7-TM_R PF06814.13 GAX23593.1 - 8.8e-45 153.2 9.9 1.1e-44 152.9 9.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3566 PF12089.8 GAX23593.1 - 0.023 15.0 2.3 0.055 13.8 2.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) DUF2207 PF09972.9 GAX23593.1 - 1.2 7.8 5.3 2.3 6.9 5.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Histone PF00125.24 GAX23594.1 - 9.5e-54 181.3 2.2 1.1e-53 181.1 2.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GAX23594.1 - 0.00014 22.5 1.6 0.00016 22.3 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GAX23594.1 - 0.00037 20.6 0.5 0.00057 20.0 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX23594.1 - 0.00044 20.6 0.0 0.00068 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAX23594.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAX23594.1 - 0.086 12.9 0.1 0.16 12.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Lar_N PF09861.9 GAX23595.1 - 1.9e-10 40.3 0.2 3.5e-05 23.1 0.0 3.0 2 1 0 2 2 2 2 Lactate racemase N-terminal domain MMR_HSR1 PF01926.23 GAX23596.1 - 6.1e-24 84.3 0.0 2.6e-23 82.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX23596.1 - 2.1e-08 33.9 0.1 7.9e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.13 GAX23596.1 - 2.3e-08 34.1 0.5 2.3e-08 34.1 0.5 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF933) Dynamin_N PF00350.23 GAX23596.1 - 0.018 15.1 0.1 11 6.1 0.0 2.9 3 1 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 GAX23596.1 - 0.038 13.9 0.1 0.72 9.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 GAX23596.1 - 0.041 14.4 0.1 1.1 9.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 GAX23596.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Toprim_3 PF13362.6 GAX23596.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Toprim domain AAA_23 PF13476.6 GAX23596.1 - 0.087 13.3 0.1 8.5 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 GAX23596.1 - 0.092 12.4 0.0 0.12 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GAX23596.1 - 0.094 13.2 0.2 0.48 10.9 0.0 2.1 3 0 0 3 3 3 0 ABC transporter AAA_22 PF13401.6 GAX23596.1 - 0.16 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Asp_Arg_Hydrox PF05118.15 GAX23597.1 - 1.1e-36 126.0 0.0 2e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Acetyltransf_1 PF00583.25 GAX23598.1 - 3.9e-11 43.2 0.0 9.5e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX23598.1 - 5.3e-07 29.6 0.0 8.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX23598.1 - 3.2e-06 27.5 0.0 5.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX23598.1 - 0.0016 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAX23598.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HA PF03457.14 GAX23599.1 - 8.7e-25 86.8 1.7 9.4e-09 35.5 0.0 4.4 4 1 0 4 4 4 4 Helicase associated domain RRM_1 PF00076.22 GAX23600.1 - 3e-11 43.0 0.0 1.2e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC3_N PF07034.11 GAX23600.1 - 0.00056 19.1 2.3 0.00093 18.4 2.3 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF5619 PF18505.1 GAX23600.1 - 0.035 14.1 0.8 0.087 12.8 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) SmAKAP PF15127.6 GAX23600.1 - 2.9 9.1 7.1 1.2 10.4 0.1 3.2 2 1 1 3 3 3 0 Small membrane A-kinase anchor protein RST PF12174.8 GAX23602.1 - 0.023 14.6 0.3 0.05 13.5 0.3 1.6 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain DUF3987 PF13148.6 GAX23602.1 - 9.7 5.1 11.8 8.5 5.3 11.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4407 PF14362.6 GAX23602.1 - 10 5.4 10.7 11 5.3 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEAD PF00270.29 GAX23603.1 - 3.8e-39 134.3 0.2 5.7e-39 133.7 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX23603.1 - 1.3e-24 86.6 0.0 7.9e-24 84.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAX23603.1 - 6.8e-11 42.2 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 GAX23603.1 - 0.00054 19.2 0.0 0.00089 18.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAX23603.1 - 0.0022 18.0 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAX23603.1 - 0.1 11.9 1.2 0.31 10.4 0.0 2.3 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit LON_substr_bdg PF02190.16 GAX23604.1 - 6.4e-09 36.0 0.0 7.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Adap_comp_sub PF00928.21 GAX23605.1 - 8.4e-65 218.8 0.0 1e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAX23605.1 - 0.0012 18.8 0.0 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Longin PF13774.6 GAX23605.1 - 0.0044 17.0 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Chlorosome_CsmC PF11098.8 GAX23605.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C Gemini_AL2 PF01440.16 GAX23606.1 - 0.74 10.3 3.2 5.8 7.4 1.4 2.6 2 0 0 2 2 2 0 Geminivirus AL2 protein TPR_2 PF07719.17 GAX23607.1 - 3.2e-28 95.5 23.8 5.5e-05 23.0 0.1 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 GAX23607.1 - 1.3e-26 91.0 29.6 0.0022 18.7 0.0 10.6 6 2 5 11 11 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 GAX23607.1 - 1.9e-23 82.8 14.6 3.5e-05 24.2 0.1 7.2 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23607.1 - 5.2e-22 76.2 5.8 0.0071 16.5 0.1 10.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23607.1 - 6.6e-22 77.6 24.6 0.00042 20.5 0.9 8.3 3 2 4 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23607.1 - 6.7e-22 76.4 10.1 0.00018 21.2 0.1 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAX23607.1 - 1.3e-21 76.9 31.7 4.4e-08 33.6 0.3 8.4 7 3 2 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAX23607.1 - 1.3e-19 69.1 2.0 0.046 14.1 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23607.1 - 1.7e-12 46.4 17.0 0.11 12.6 0.0 10.1 9 2 2 11 11 10 4 Tetratricopeptide repeat TPR_15 PF13429.6 GAX23607.1 - 1.8e-09 37.2 17.6 1.6e-05 24.3 0.1 6.2 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23607.1 - 1.6e-08 34.7 21.6 8.5 7.3 0.0 10.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX23607.1 - 1.2e-07 31.7 14.7 0.17 12.0 0.1 7.0 6 2 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX23607.1 - 1.5e-07 31.5 0.1 0.4 11.0 0.0 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAX23607.1 - 1e-06 28.3 6.6 0.00062 19.4 0.0 6.0 7 0 0 7 7 7 1 TPR repeat Suf PF05843.14 GAX23607.1 - 7e-06 26.2 0.2 0.67 9.9 0.1 3.8 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_10 PF13374.6 GAX23607.1 - 0.00027 20.7 23.4 0.38 10.7 0.3 7.3 9 0 0 9 9 9 3 Tetratricopeptide repeat PPR PF01535.20 GAX23607.1 - 0.00042 20.4 3.3 3.4 8.1 0.3 6.1 7 0 0 7 7 7 1 PPR repeat Mad3_BUB1_I PF08311.12 GAX23607.1 - 0.059 13.3 7.1 58 3.7 0.0 6.3 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 HAGH_C PF16123.5 GAX23607.1 - 0.1 13.1 0.0 0.46 11.0 0.0 2.1 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus TPR_4 PF07721.14 GAX23607.1 - 0.11 13.1 17.7 17 6.4 0.3 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 GAX23607.1 - 0.16 12.0 7.6 34 4.6 0.2 6.1 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain NAC PF01849.18 GAX23608.1 - 2.3e-24 85.1 0.1 4.2e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain ATP11 PF06644.11 GAX23609.1 - 7.7e-23 81.6 0.1 9.2e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein Tex_N PF09371.10 GAX23609.1 - 0.056 13.1 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain zf-RanBP PF00641.18 GAX23610.1 - 9.6e-07 28.0 1.7 2.2e-06 26.8 1.7 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others EF-hand_7 PF13499.6 GAX23610.1 - 0.0067 16.9 0.7 0.04 14.4 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX23610.1 - 0.5 10.4 1.5 19 5.5 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain PilJ PF13675.6 GAX23611.1 - 0.0049 16.9 2.1 0.49 10.4 0.0 3.0 2 1 1 3 3 3 2 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1648 PF07853.11 GAX23611.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Syntaxin_2 PF14523.6 GAX23611.1 - 1.2 9.6 5.2 1.4 9.3 1.3 2.5 2 0 0 2 2 2 0 Syntaxin-like protein SF1-HH PF16275.5 GAX23612.1 - 4.9e-17 62.3 0.9 4.9e-17 62.3 0.9 2.3 2 1 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 GAX23612.1 - 2.3e-10 40.1 0.8 4.8e-10 39.1 0.8 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 GAX23612.1 - 0.00094 19.1 8.1 0.001 19.1 1.9 2.6 2 0 0 2 2 2 1 Zinc knuckle PHD_4 PF16866.5 GAX23612.1 - 0.0019 18.2 2.3 0.0046 17.0 2.3 1.6 1 0 0 1 1 1 1 PHD-finger zf-CCHC_3 PF13917.6 GAX23612.1 - 0.0073 16.3 2.4 0.012 15.6 1.2 1.9 1 1 1 2 2 2 1 Zinc knuckle SlyX PF04102.12 GAX23612.1 - 3 8.5 6.4 0.65 10.7 1.5 2.5 2 0 0 2 2 2 0 SlyX zf-CCHC_4 PF14392.6 GAX23612.1 - 4.4 7.1 4.9 3.5 7.4 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Methyltr_RsmB-F PF01189.17 GAX23613.1 - 1.5e-12 47.6 0.1 2.8e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 GAX23613.1 - 4.5e-05 23.3 1.1 0.0001 22.2 1.1 1.6 1 1 0 1 1 1 1 PUA domain FtsJ PF01728.19 GAX23613.1 - 0.04 14.0 0.1 0.095 12.8 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 GAX23613.1 - 0.056 14.1 0.0 0.19 12.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF892 PF05974.12 GAX23613.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) MMR_HSR1 PF01926.23 GAX23614.1 - 3.8e-18 65.6 0.0 1e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX23614.1 - 0.0002 21.3 0.1 0.023 14.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 GAX23614.1 - 0.00075 19.1 0.2 0.0085 15.6 0.2 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF4674 PF15719.5 GAX23614.1 - 0.0096 16.0 4.8 0.021 14.8 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) Dynamin_N PF00350.23 GAX23614.1 - 0.035 14.2 3.5 1.3 9.0 0.2 3.1 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.22 GAX23614.1 - 0.11 12.9 0.3 28 5.2 0.0 2.7 3 0 0 3 3 3 0 RNA helicase Mem_trans PF03547.18 GAX23614.1 - 0.2 10.0 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein Mpp10 PF04006.12 GAX23615.1 - 5.1e-109 365.5 82.1 1.9e-98 330.5 34.8 2.1 1 1 0 2 2 2 2 Mpp10 protein GFO_IDH_MocA PF01408.22 GAX23616.1 - 1.6e-20 74.1 0.0 2.7e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 GAX23616.1 - 0.013 15.6 0.0 0.045 13.8 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 GAX23616.1 - 0.029 15.0 0.0 0.048 14.3 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF1336 PF07059.12 GAX23617.1 - 2.4e-46 158.6 0.0 3.6e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 GAX23617.1 - 0.00054 20.4 0.0 0.01 16.4 0.0 2.6 1 1 0 1 1 1 1 PH domain DUF4886 PF16227.5 GAX23618.1 - 4.5e-07 29.3 0.0 7.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4886) DUF4886 PF16227.5 GAX23619.1 - 7.6e-05 22.0 0.2 0.00038 19.7 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4886) ABC_membrane PF00664.23 GAX23620.1 - 0.061 13.0 0.3 0.17 11.5 0.3 1.6 2 0 0 2 2 2 0 ABC transporter transmembrane region DRMBL PF07522.14 GAX23621.1 - 8.1e-22 77.5 0.0 2e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase UBA PF00627.31 GAX23621.1 - 7e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Lactamase_B_2 PF12706.7 GAX23621.1 - 0.0001 21.9 0.7 0.00018 21.1 0.7 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX23621.1 - 0.0017 18.4 1.8 0.0029 17.6 1.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 GAX23621.1 - 0.0047 16.8 0.1 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain CIA30 PF08547.12 GAX23622.1 - 1e-12 48.4 0.2 1.3e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RPN1_RPN2_N PF17781.1 GAX23623.1 - 4.2e-107 358.1 0.4 9.2e-107 357.0 0.4 1.6 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 GAX23623.1 - 5e-31 106.5 0.1 1.1e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 GAX23623.1 - 2.6e-23 81.2 25.9 3.3e-05 24.1 0.2 8.9 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAX23623.1 - 7.5e-07 29.5 2.5 0.87 10.0 0.0 5.4 3 2 1 5 5 5 3 HEAT repeats TPR_15 PF13429.6 GAX23623.1 - 0.00066 19.0 0.1 0.0017 17.6 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 GAX23623.1 - 0.0014 19.0 1.2 0.31 11.6 0.1 3.7 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 GAX23623.1 - 0.39 11.1 1.4 13 6.3 0.0 4.1 5 0 0 5 5 5 0 HEAT repeat PseudoU_synth_2 PF00849.22 GAX23624.1 - 7.9e-22 78.0 0.0 1.6e-21 77.1 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase Sec62 PF03839.16 GAX23625.1 - 2.8e-29 102.2 3.8 2.8e-29 102.2 3.8 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 SAC3_GANP PF03399.16 GAX23626.1 - 4.7e-21 75.4 0.5 2.4e-11 43.6 0.1 2.1 2 0 0 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAX23626.1 - 0.00028 20.9 0.1 0.00049 20.1 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Cactin_mid PF10312.9 GAX23626.1 - 0.097 12.4 0.9 0.25 11.1 0.6 1.8 2 0 0 2 2 2 0 Conserved mid region of cactin DUF759 PF05537.11 GAX23626.1 - 0.37 9.6 2.7 0.38 9.6 1.4 1.6 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) Rad9 PF04139.13 GAX23628.1 - 8.7e-23 81.0 0.2 1.1e-22 80.7 0.2 1.2 1 0 0 1 1 1 1 Rad9 DUF3666 PF12408.8 GAX23628.1 - 0.23 10.7 1.4 3.2 7.0 0.2 2.4 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase Prefoldin PF02996.17 GAX23629.1 - 2.1e-24 85.7 1.2 2.7e-24 85.4 1.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF5082 PF16888.5 GAX23629.1 - 0.061 13.6 0.4 0.12 12.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) UPF0020 PF01170.18 GAX23630.1 - 1.6e-05 24.7 0.1 0.00063 19.5 0.0 2.4 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 GAX23630.1 - 2.5e-05 24.2 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX23630.1 - 3e-05 24.7 0.0 6.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX23630.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX23630.1 - 0.004 17.8 0.0 0.0095 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 GAX23630.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_15 PF09445.10 GAX23630.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.14 GAX23630.1 - 0.18 11.2 0.0 0.91 8.9 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB PWI PF01480.17 GAX23631.1 - 7.5e-21 74.2 0.1 1.2e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 PWI domain BRF1 PF07741.13 GAX23631.1 - 2.6 8.4 5.6 0.31 11.4 0.4 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain XPC-binding PF09280.11 GAX23632.1 - 4.5e-21 74.3 15.2 4.5e-21 74.3 15.2 3.3 3 1 0 3 3 2 1 XPC-binding domain UBA PF00627.31 GAX23632.1 - 3.1e-19 68.5 6.9 3.9e-09 36.2 0.0 3.2 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 GAX23632.1 - 1.2e-18 66.6 0.3 2.1e-18 65.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX23632.1 - 1.9e-07 30.8 0.3 3.2e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAX23632.1 - 0.0001 22.8 0.0 0.00023 21.7 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX23632.1 - 0.00022 21.3 0.3 0.00041 20.4 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like WIYLD PF10440.9 GAX23632.1 - 0.00051 19.8 0.1 0.41 10.5 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-binding WIYLD domain Ubiquitin_4 PF18036.1 GAX23632.1 - 0.00096 19.1 0.4 0.042 13.9 0.2 2.3 1 1 1 2 2 2 1 Ubiquitin-like domain TFIIA PF03153.13 GAX23632.1 - 0.032 14.3 12.5 0.043 13.8 12.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UBA_3 PF09288.10 GAX23632.1 - 0.14 12.0 0.0 19 5.1 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain CUE PF02845.16 GAX23632.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.2 5 0 0 5 5 4 0 CUE domain RHH_1 PF01402.21 GAX23632.1 - 0.23 11.5 0.3 23 5.1 0.1 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family FliG_N PF14842.6 GAX23632.1 - 0.45 11.1 0.1 0.45 11.1 0.1 3.0 2 1 1 3 3 3 0 FliG N-terminal domain DUF3617 PF12276.8 GAX23632.1 - 2.4 8.5 10.0 1.1e+03 -0.2 10.0 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) 2OG-FeII_Oxy_2 PF13532.6 GAX23635.1 - 8.7e-24 84.8 2.1 7.7e-13 49.1 0.3 2.8 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily YycC PF14174.6 GAX23635.1 - 0.26 11.1 2.1 0.98 9.3 0.7 2.2 2 0 0 2 2 2 0 YycC-like protein BssC_TutF PF08201.11 GAX23635.1 - 9.8 6.3 9.1 7.3 6.7 0.1 3.9 5 0 0 5 5 5 0 BssC/TutF protein Mito_carr PF00153.27 GAX23636.1 - 6.1e-71 234.4 4.2 5.9e-25 87.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LapA_dom PF06305.11 GAX23636.1 - 0.082 12.7 0.1 0.36 10.7 0.1 2.1 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain HTH_28 PF13518.6 GAX23636.1 - 1.4 9.1 5.4 10 6.4 1.7 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain GSH_synth_ATP PF03917.17 GAX23637.1 - 2.8e-110 368.7 0.0 3.4e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 GAX23637.1 - 1.7e-28 99.1 0.0 2.9e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EF-hand_8 PF13833.6 GAX23638.1 - 9.1e-06 25.4 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 GAX23638.1 - 0.02 15.4 0.1 0.055 13.9 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair APCDDC PF14921.6 GAX23638.1 - 0.23 10.9 0.3 8.4 5.8 0.1 2.1 2 0 0 2 2 2 0 Adenomatosis polyposis coli down-regulated 1 CorA PF01544.18 GAX23638.1 - 0.33 10.2 11.3 0.49 9.7 8.0 2.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein SAP130_C PF16014.5 GAX23639.1 - 0.66 9.0 3.5 1.1 8.3 3.5 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus zf-MIZ PF02891.20 GAX23640.1 - 0.061 13.1 0.3 0.25 11.1 0.3 2.1 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FTCD_C PF04961.12 GAX23641.1 - 8e-36 123.5 2.0 9.8e-36 123.2 2.0 1.1 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase DUF3482 PF11981.8 GAX23641.1 - 1.7 8.0 7.5 6.5 6.1 5.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3482) cpYpsA PF12694.7 GAX23642.1 - 0.046 13.5 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family DUF3258 PF11646.8 GAX23642.1 - 0.065 13.4 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF3258 Fer2 PF00111.27 GAX23644.1 - 3.2e-10 39.8 0.3 4.4e-10 39.4 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain tRNA-synt_2d PF01409.20 GAX23645.1 - 1.1e-86 290.3 0.0 1.5e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 GAX23645.1 - 2.7e-16 59.6 2.3 6.1e-16 58.5 1.4 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 GAX23645.1 - 2.1e-09 37.0 0.0 7.4e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 GAX23645.1 - 1.1e-06 28.3 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 GAX23645.1 - 5.1e-05 22.5 0.0 0.00014 21.1 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 GAX23645.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) IlvC PF01450.19 GAX23645.1 - 0.03 14.6 0.4 0.071 13.4 0.4 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain HTH_30 PF13556.6 GAX23645.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Pkinase PF00069.25 GAX23646.1 - 1.2e-54 185.5 0.0 1.4e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23646.1 - 6.6e-43 146.9 0.0 1.1e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX23646.1 - 0.00031 19.7 0.0 0.00054 18.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAX23646.1 - 0.0034 16.4 0.0 0.011 14.7 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAX23646.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAX23646.1 - 0.037 13.9 0.2 0.058 13.3 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3418 PF11898.8 GAX23647.1 - 0.016 13.9 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) HA2 PF04408.23 GAX23648.1 - 7e-18 64.9 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAX23648.1 - 2.9e-11 43.7 0.0 9.2e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX23648.1 - 6.1e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 GAX23648.1 - 2.1e-07 31.2 0.0 4.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 GAX23648.1 - 1.2e-05 25.6 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX23648.1 - 0.00073 19.3 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX23648.1 - 0.031 14.8 0.0 0.084 13.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAX23648.1 - 0.078 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 GAX23648.1 - 0.13 11.5 0.0 0.45 9.8 0.0 1.8 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 GAX23648.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Polyketide_cyc2 PF10604.9 GAX23649.1 - 4e-10 40.1 0.2 5.6e-10 39.6 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX23649.1 - 4.6e-06 26.9 0.9 1.3e-05 25.4 0.6 1.9 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Sel1 PF08238.12 GAX23650.1 - 3.7e-22 78.3 12.8 1.9e-08 34.7 0.8 5.4 5 0 0 5 5 5 5 Sel1 repeat 5-FTHF_cyc-lig PF01812.20 GAX23652.1 - 1e-43 149.4 0.0 1.4e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family adh_short PF00106.25 GAX23653.1 - 1.3e-44 152.0 0.0 1.6e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX23653.1 - 1.5e-25 90.2 0.0 1.8e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX23653.1 - 8.7e-09 35.5 0.0 1.7e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX23653.1 - 0.0036 16.5 0.1 0.0055 15.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Tachykinin PF02202.16 GAX23653.1 - 0.026 14.4 0.3 0.086 12.8 0.3 1.9 1 0 0 1 1 1 0 Tachykinin family F420_oxidored PF03807.17 GAX23653.1 - 0.069 13.7 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 GAX23653.1 - 0.076 12.5 0.3 0.52 9.7 0.3 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 GAX23653.1 - 0.086 12.4 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 SLOG cluster4 family ApbA PF02558.16 GAX23653.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 GAX23653.1 - 0.14 12.0 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MRI PF15325.6 GAX23654.1 - 0.016 16.3 0.1 0.027 15.5 0.1 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection IF-2B PF01008.17 GAX23655.1 - 4.4e-52 177.0 0.0 6.1e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DS PF01916.17 GAX23655.1 - 0.046 13.0 0.1 2.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Deoxyhypusine synthase GlcNAc PF11397.8 GAX23656.1 - 7.4e-52 176.9 4.0 3.5e-41 141.8 1.6 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) DUF5454 PF17535.2 GAX23656.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5454) Glycos_transf_2 PF00535.26 GAX23656.1 - 0.076 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 MitMem_reg PF13012.6 GAX23657.1 - 1.5e-29 102.7 0.9 2.8e-29 101.8 0.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAX23657.1 - 5e-28 97.4 0.8 8e-28 96.8 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF442 PF04273.13 GAX23657.1 - 0.17 12.0 0.0 0.52 10.4 0.0 1.8 1 1 0 1 1 1 0 Putative phosphatase (DUF442) IMS PF00817.20 GAX23658.1 - 8.9e-32 110.2 0.0 9.1e-31 106.9 0.0 2.5 2 1 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 GAX23658.1 - 1.5e-10 41.8 0.0 3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAX23658.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif TRAPPC-Trs85 PF12739.7 GAX23658.1 - 0.077 11.9 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit RCC1 PF00415.18 GAX23659.1 - 2e-43 146.8 19.7 1.8e-12 47.7 0.4 8.6 8 2 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX23659.1 - 4.8e-38 128.2 26.8 3.9e-10 39.3 0.1 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat ChaC PF04752.12 GAX23659.1 - 7.3e-32 110.8 0.0 1.2e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 GAX23659.1 - 1.2e-05 25.9 0.0 4.2e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Kelch_4 PF13418.6 GAX23659.1 - 1.4 9.0 5.0 97 3.1 0.0 5.0 6 0 0 6 6 6 0 Galactose oxidase, central domain F-box PF00646.33 GAX23660.1 - 0.035 14.0 0.6 0.09 12.7 0.6 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 GAX23660.1 - 0.17 11.8 0.9 0.39 10.7 0.9 1.6 1 0 0 1 1 1 0 F-box-like SGT1 PF07093.11 GAX23660.1 - 0.32 9.4 3.8 0.38 9.1 3.8 1.1 1 0 0 1 1 1 0 SGT1 protein Romo1 PF10247.9 GAX23661.1 - 0.00015 22.0 3.0 0.036 14.4 0.2 2.3 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 GAX23661.1 - 0.039 14.3 1.5 0.06 13.7 1.5 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RNA_pol_Rpb1_1 PF04997.12 GAX23662.1 - 3.7e-89 299.1 0.0 6.5e-89 298.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAX23662.1 - 2.6e-83 279.6 0.6 3.7e-83 279.1 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAX23662.1 - 1.1e-73 247.0 0.0 1.8e-73 246.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAX23662.1 - 3.6e-32 111.5 0.0 2e-31 109.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAX23662.1 - 3e-27 94.7 0.0 8.3e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-tcix PF14952.6 GAX23662.1 - 0.15 11.7 3.4 0.45 10.2 3.4 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Pyridox_oxase_2 PF12766.7 GAX23663.1 - 3.9e-27 94.8 0.1 5.3e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 GAX23663.1 - 6.8e-05 23.0 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pho88 PF10032.9 GAX23664.1 - 8.7e-31 106.6 0.6 1.9e-30 105.5 0.6 1.5 1 1 0 1 1 1 1 Phosphate transport (Pho88) Rad54_N PF08658.10 GAX23664.1 - 0.077 13.1 0.3 0.077 13.1 0.3 2.1 2 0 0 2 2 2 0 Rad54 N terminal SDA1 PF05285.12 GAX23664.1 - 0.24 10.8 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 SDA1 TLP-20 PF06088.11 GAX23664.1 - 1.2 9.1 7.4 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Tim54 PF11711.8 GAX23664.1 - 4.4 6.0 8.6 16 4.2 0.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Inositol_P PF00459.25 GAX23665.1 - 4.9e-60 203.4 0.0 6.9e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family MAM33 PF02330.16 GAX23666.1 - 4.7e-36 124.7 2.3 7e-36 124.2 2.3 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Ndc80_HEC PF03801.13 GAX23667.1 - 9.3e-38 129.3 0.0 2.5e-37 127.8 0.0 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family zf-C4H2 PF10146.9 GAX23667.1 - 4.9e-05 23.7 29.4 0.00023 21.6 9.5 2.5 2 0 0 2 2 2 2 Zinc finger-containing protein Spc7 PF08317.11 GAX23667.1 - 8.4e-05 21.6 17.4 8.4e-05 21.6 17.4 3.4 1 1 2 3 3 3 2 Spc7 kinetochore protein IFT57 PF10498.9 GAX23667.1 - 8.5e-05 21.7 8.4 8.5e-05 21.7 8.4 3.1 2 1 1 3 3 3 1 Intra-flagellar transport protein 57 CALCOCO1 PF07888.11 GAX23667.1 - 0.00081 18.4 16.9 0.00081 18.4 16.9 2.2 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like KASH_CCD PF14662.6 GAX23667.1 - 0.0079 16.0 20.7 0.0079 16.0 20.7 3.0 1 1 2 3 3 2 1 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 GAX23667.1 - 0.017 15.3 33.9 0.47 10.6 11.2 3.9 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 GAX23667.1 - 0.044 13.8 18.7 0.53 10.3 7.4 2.8 2 1 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 GAX23667.1 - 0.047 14.0 29.3 0.057 13.7 4.4 5.1 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 GAX23667.1 - 0.2 10.7 28.5 0.071 12.2 10.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 GAX23667.1 - 0.23 10.8 25.5 0.91 8.8 9.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DASH_Duo1 PF08651.10 GAX23667.1 - 0.37 10.6 9.1 3 7.7 0.6 3.8 3 1 0 3 3 3 0 DASH complex subunit Duo1 AAA_13 PF13166.6 GAX23667.1 - 0.44 9.1 36.0 0.043 12.5 15.6 2.2 1 1 2 3 3 3 0 AAA domain DASH_Dam1 PF08653.10 GAX23667.1 - 0.53 10.1 3.9 1.2 9.0 0.6 3.1 1 1 1 2 2 2 0 DASH complex subunit Dam1 MAD PF05557.13 GAX23667.1 - 8.9 4.5 45.9 2.2 6.6 20.4 2.1 1 1 0 2 2 2 0 Mitotic checkpoint protein Bacillus_HBL PF05791.11 GAX23667.1 - 9.8 6.0 21.6 0.41 10.5 5.7 3.7 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) PTN_MK_N PF05196.13 GAX23668.1 - 0.27 11.5 1.1 0.62 10.3 0.2 2.0 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain HSP90 PF00183.18 GAX23669.1 - 2.6e-231 769.0 24.2 3.2e-231 768.7 24.2 1.0 1 0 0 1 1 1 1 Hsp90 protein Dynamin_M PF01031.20 GAX23670.1 - 6.6e-97 324.2 0.0 1e-96 323.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GAX23670.1 - 3.9e-53 179.9 0.0 7.6e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GAX23670.1 - 3.3e-30 104.1 0.3 7.1e-30 103.0 0.3 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAX23670.1 - 0.00026 21.1 0.2 0.0016 18.5 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAX23670.1 - 0.035 13.4 0.2 8.1 5.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Renin_r PF07850.14 GAX23671.1 - 1.4e-05 25.6 0.0 3.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Renin receptor-like protein PglL_A PF15864.5 GAX23672.1 - 3.5 7.4 8.8 0.67 9.7 1.0 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase Pkinase PF00069.25 GAX23673.1 - 1.2e-45 156.0 0.0 9.7e-33 113.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23673.1 - 6.7e-20 71.5 0.5 4.2e-10 39.3 0.0 3.9 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 GAX23673.1 - 3.9e-13 49.7 0.0 9.3e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 RWD domain Peptidase_C10 PF01640.17 GAX23673.1 - 0.12 12.7 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 Peptidase C10 family APH PF01636.23 GAX23673.1 - 0.96 9.3 4.1 0.63 9.9 0.2 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Arf PF00025.21 GAX23674.1 - 2.1e-63 212.9 0.0 2.4e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAX23674.1 - 3.3e-10 39.7 0.0 4.2e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAX23674.1 - 3.4e-10 39.6 0.1 1.7e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAX23674.1 - 4.7e-09 36.5 0.0 9.2e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX23674.1 - 1.9e-08 34.1 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAX23674.1 - 1.1e-07 31.9 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX23674.1 - 9.7e-06 25.1 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Antibiotic_NAT PF02522.14 GAX23674.1 - 0.0098 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase PduV-EutP PF10662.9 GAX23674.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 GAX23674.1 - 0.068 13.1 0.1 6.8 6.6 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 GAX23674.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GAX23675.1 - 6.1e-16 59.1 0.0 2.6e-07 31.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX23675.1 - 1.4e-05 25.1 0.0 8.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX23675.1 - 3.2e-05 24.4 0.0 7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX23675.1 - 0.00045 20.5 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX23675.1 - 0.0021 18.6 0.0 0.0075 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAX23675.1 - 0.0023 17.7 0.1 0.021 14.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 GAX23675.1 - 0.0025 18.0 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAX23675.1 - 0.0053 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX23675.1 - 0.008 16.0 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAX23675.1 - 0.023 13.9 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAX23675.1 - 0.023 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 GAX23675.1 - 0.028 14.2 0.0 0.079 12.7 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain KAP_NTPase PF07693.14 GAX23675.1 - 0.028 13.6 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 GAX23675.1 - 0.031 14.6 0.0 0.12 12.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase MMR_HSR1 PF01926.23 GAX23675.1 - 0.031 14.3 0.1 0.12 12.4 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 GAX23675.1 - 0.032 13.5 0.1 0.091 12.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 GAX23675.1 - 0.038 14.5 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 GAX23675.1 - 0.047 13.3 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 GAX23675.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GAX23675.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DivIC PF04977.15 GAX23675.1 - 0.076 12.8 0.2 18 5.2 0.0 2.9 2 0 0 2 2 2 0 Septum formation initiator LppA PF16708.5 GAX23675.1 - 0.098 12.6 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium AAA_30 PF13604.6 GAX23675.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX23675.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 GAX23675.1 - 0.11 12.0 0.1 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Fes1 PF08609.10 GAX23675.1 - 0.71 10.8 2.5 1.6 9.6 0.6 2.6 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Aldo_ket_red PF00248.21 GAX23676.1 - 8.5e-46 156.5 0.0 1.1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HATPase_c PF02518.26 GAX23677.1 - 5.1e-12 46.3 0.0 1.1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX23677.1 - 1.2e-09 38.1 0.0 2.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Topo-VIb_trans PF09239.11 GAX23677.1 - 0.0075 16.1 0.0 0.49 10.2 0.0 2.4 2 0 0 2 2 2 1 Topoisomerase VI B subunit, transducer HATPase_c_5 PF14501.6 GAX23677.1 - 0.039 13.9 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 GHKL domain PTS_EIIB PF00367.20 GAX23677.1 - 0.089 12.3 0.2 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 phosphotransferase system, EIIB Ribosomal_L32p PF01783.23 GAX23677.1 - 0.094 13.0 0.2 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L32p protein family CN_hydrolase PF00795.22 GAX23678.1 - 3e-33 115.3 0.0 4.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 GAX23678.1 - 3.1e-26 92.0 0.0 1.2e-25 90.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 GAX23678.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Asparagine synthase Pyr_redox_2 PF07992.14 GAX23679.1 - 3.3e-32 111.9 0.0 5e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX23679.1 - 3.7e-21 75.7 0.0 4.8e-17 62.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.24 GAX23679.1 - 1.8e-11 44.0 0.0 3.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin FAD_binding_2 PF00890.24 GAX23679.1 - 8.6e-10 38.3 8.9 0.00013 21.1 0.9 3.7 3 1 1 4 4 4 3 FAD binding domain Pyr_redox PF00070.27 GAX23679.1 - 1.2e-06 29.0 0.2 5e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX23679.1 - 2.3e-06 27.0 4.0 0.026 13.6 0.0 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAX23679.1 - 2.5e-06 27.1 4.2 0.00023 20.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX23679.1 - 2.9e-06 26.3 2.9 0.0053 15.5 0.2 4.0 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 GAX23679.1 - 2.1e-05 23.8 0.5 0.0027 16.9 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 GAX23679.1 - 0.0002 20.7 3.1 0.075 12.3 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 GAX23679.1 - 0.00023 20.5 2.7 0.0098 15.1 0.3 2.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 GAX23679.1 - 0.00025 21.2 1.8 0.012 15.9 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 GAX23679.1 - 0.0021 17.4 0.5 0.68 9.2 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX23679.1 - 0.0033 17.0 6.4 0.59 9.6 0.8 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX23679.1 - 0.0037 16.4 1.4 0.63 9.0 0.7 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_7 PF13241.6 GAX23679.1 - 0.088 13.3 0.0 0.35 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 GAX23679.1 - 0.65 8.8 3.0 1.9 7.2 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.24 GAX23680.1 - 2e-39 135.8 15.1 2.6e-39 135.3 15.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX23680.1 - 2.3e-30 105.7 28.8 3.2e-30 105.3 28.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily eIF-1a PF01176.19 GAX23682.1 - 1.2e-21 76.2 0.0 1.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 GAX23682.1 - 0.0017 18.1 0.0 0.044 13.5 0.0 2.2 2 0 0 2 2 2 1 RsgA N-terminal domain Adaptin_binding PF10199.9 GAX23683.1 - 3.6e-06 27.6 12.6 9.9e-06 26.2 12.6 1.8 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF3439 PF11921.8 GAX23683.1 - 0.015 15.2 0.4 0.031 14.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TED PF08341.11 GAX23683.1 - 0.072 13.5 1.2 0.13 12.6 0.2 2.0 2 0 0 2 2 2 0 Thioester domain Methyltransf_12 PF08242.12 GAX23684.1 - 0.00013 22.6 0.0 0.00021 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX23684.1 - 0.0004 21.0 0.0 0.00065 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX23684.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX23684.1 - 0.0029 17.6 0.0 0.0074 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAX23684.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 GAX23684.1 - 0.0085 15.9 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX23684.1 - 0.011 16.4 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 GAX23684.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 GAX23684.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 GAX23684.1 - 0.032 13.7 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Nudc_N PF14050.6 GAX23686.1 - 2.6e-19 68.9 0.2 4.6e-19 68.2 0.2 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 GAX23686.1 - 7.8e-13 49.2 0.1 2.2e-12 47.8 0.1 1.7 2 0 0 2 2 2 1 CS domain MMR_HSR1 PF01926.23 GAX23687.1 - 9.5e-05 22.5 0.1 0.00023 21.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX23687.1 - 0.00032 20.3 0.4 0.00072 19.1 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Pox_polyA_pol_C PF12629.7 GAX23687.1 - 0.0024 17.7 0.0 0.0048 16.8 0.0 1.5 2 0 0 2 2 2 1 Poxvirus poly(A) polymerase C-terminal domain Dynamin_N PF00350.23 GAX23687.1 - 0.0046 17.0 0.1 0.0098 16.0 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Arf PF00025.21 GAX23687.1 - 0.0058 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family NOG1 PF06858.14 GAX23687.1 - 0.011 15.5 0.8 0.032 14.0 0.3 2.1 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Gtr1_RagA PF04670.12 GAX23687.1 - 0.011 15.1 0.3 0.12 11.7 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MHC_II_beta PF00969.19 GAX23687.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain LRR_6 PF13516.6 GAX23688.1 - 2.9e-24 83.0 18.1 3e-05 23.7 0.1 9.0 9 0 0 9 9 9 6 Leucine Rich repeat LRR_1 PF00560.33 GAX23688.1 - 1.5e-09 37.0 0.3 0.59 10.9 0.0 6.3 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_4 PF12799.7 GAX23688.1 - 6.8e-05 23.2 4.2 0.0045 17.4 0.5 4.4 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX23688.1 - 0.016 14.9 2.7 16 5.4 0.0 4.2 4 1 1 5 5 5 0 Leucine rich repeat Lipase_GDSL_2 PF13472.6 GAX23690.1 - 9e-06 26.2 0.4 0.11 12.9 0.0 3.1 3 1 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Syntaxin_2 PF14523.6 GAX23690.1 - 0.15 12.4 0.3 0.35 11.3 0.3 1.6 1 0 0 1 1 1 0 Syntaxin-like protein OmpH PF03938.14 GAX23690.1 - 2.1 8.7 5.0 4 7.8 5.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Adaptin_N PF01602.20 GAX23691.1 - 7.7e-83 278.8 0.0 1.1e-82 278.4 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAX23691.1 - 3.5e-42 144.2 0.0 9.5e-40 136.3 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 GAX23691.1 - 1.3e-10 41.3 0.0 2.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 GAX23691.1 - 7.9e-10 39.0 0.6 0.00095 19.5 0.0 4.2 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.22 GAX23691.1 - 0.00012 22.0 5.0 0.27 11.6 0.1 4.8 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 GAX23691.1 - 0.033 14.7 2.1 3.8 8.1 0.0 4.7 3 1 1 4 4 4 0 HEAT-like repeat AAA PF00004.29 GAX23692.1 - 3e-32 111.8 0.1 3.8e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX23692.1 - 9.2e-09 35.9 0.7 0.069 13.5 0.1 4.5 3 1 1 4 4 4 2 AAA ATPase domain NACHT PF05729.12 GAX23692.1 - 5.9e-07 29.6 2.3 0.32 10.9 0.0 4.3 3 1 1 4 4 4 2 NACHT domain AAA_29 PF13555.6 GAX23692.1 - 7.3e-05 22.4 1.8 0.36 10.6 0.3 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_19 PF13245.6 GAX23692.1 - 0.00014 22.2 0.4 0.07 13.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX23692.1 - 0.00043 20.6 4.2 0.49 10.7 0.2 4.0 3 1 1 4 4 3 2 AAA domain AAA_5 PF07728.14 GAX23692.1 - 0.00095 19.2 0.2 2.2 8.3 0.1 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAX23692.1 - 0.0013 18.5 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 GAX23692.1 - 0.0017 18.1 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 GAX23692.1 - 0.0094 15.3 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 GAX23692.1 - 0.013 14.9 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 GAX23692.1 - 0.015 15.9 0.9 0.51 10.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 GAX23692.1 - 0.021 14.3 0.3 3.9 6.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAX23692.1 - 0.031 14.0 0.1 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 GAX23692.1 - 0.039 13.8 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Zeta_toxin PF06414.12 GAX23692.1 - 0.051 12.9 0.5 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 GAX23692.1 - 0.057 13.6 0.6 5.3 7.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 GAX23692.1 - 0.064 13.6 0.0 8 6.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.13 GAX23692.1 - 0.094 11.9 0.2 1.3 8.1 0.1 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 GAX23692.1 - 0.14 12.7 0.2 5.9 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 GAX23692.1 - 0.15 11.4 0.0 16 4.9 0.0 2.7 2 1 0 3 3 3 0 Bacterial TniB protein AAA_30 PF13604.6 GAX23692.1 - 0.18 11.5 0.6 3 7.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 GAX23692.1 - 0.18 11.2 0.2 18 4.7 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 GAX23692.1 - 0.27 10.8 1.7 24 4.4 0.1 3.2 2 1 0 3 3 3 0 AAA domain rRNA_proc-arch PF13234.6 GAX23693.1 - 2.6e-54 185.0 0.1 4.9e-54 184.1 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 GAX23693.1 - 6e-19 68.3 0.0 1.8e-18 66.7 0.0 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 GAX23693.1 - 9.8e-18 64.5 0.1 8.2e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX23693.1 - 8.6e-08 32.5 0.0 2.2e-06 28.0 0.0 2.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 GAX23693.1 - 0.0011 19.0 0.1 0.25 11.2 0.0 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 GAX23693.1 - 0.099 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytochrom_C_2 PF01322.20 GAX23693.1 - 0.11 13.4 2.2 0.43 11.5 0.6 2.7 2 0 0 2 2 2 0 Cytochrome C' Spt5-NGN PF03439.13 GAX23695.1 - 3.1e-17 62.2 0.0 6.9e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 GAX23695.1 - 1.3e-12 47.2 26.8 3.1e-05 23.8 1.4 8.1 8 0 0 8 8 8 4 KOW motif Spt5_N PF11942.8 GAX23695.1 - 0.00055 20.9 10.1 0.00055 20.9 10.1 4.5 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 GAX23695.1 - 0.035 14.4 1.4 34 4.8 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3912) ProQ_C PF17516.2 GAX23695.1 - 4.7 6.7 5.4 5.3 6.5 0.6 3.2 3 0 0 3 3 3 0 ProQ C-terminal domain CTD PF12815.7 GAX23695.1 - 6.4 7.4 7.2 1.3 9.7 0.2 2.7 3 0 0 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 BOP1NT PF08145.12 GAX23697.1 - 1.5e-85 287.2 0.7 2.3e-85 286.7 0.7 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 GAX23697.1 - 1.2e-20 73.4 9.7 0.00018 22.2 0.0 6.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX23697.1 - 1.6e-07 31.5 0.0 0.00067 19.9 0.0 4.2 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 GAX23697.1 - 0.23 9.7 0.0 0.96 7.7 0.0 1.9 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Mpp10 PF04006.12 GAX23697.1 - 3.4 6.0 26.0 35 2.7 27.9 1.6 2 0 0 2 2 2 0 Mpp10 protein DSPc PF00782.20 GAX23698.1 - 4.4e-14 52.4 0.0 6.8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX23698.1 - 0.0028 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAX23698.1 - 0.047 13.8 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate UPF0172 PF03665.13 GAX23699.1 - 9.2e-20 71.5 0.0 1.1e-19 71.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 GAX23699.1 - 0.0021 18.0 0.5 0.02 14.9 0.5 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RRM_3 PF08777.11 GAX23700.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 GAX23700.1 - 0.0046 16.8 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.29 GAX23701.1 - 4e-09 36.2 8.8 4e-09 36.2 8.8 1.9 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 GAX23701.1 - 0.0065 16.1 6.0 0.0072 16.0 3.8 2.2 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain DDT PF02791.17 GAX23701.1 - 0.021 15.1 0.1 0.046 14.0 0.1 1.6 1 0 0 1 1 1 0 DDT domain Prok-RING_1 PF14446.6 GAX23701.1 - 0.039 13.9 6.5 0.096 12.6 6.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 GAX23701.1 - 0.068 12.7 2.1 0.14 11.7 2.1 1.6 1 0 0 1 1 1 0 PHD-finger Peptidase_A17 PF05380.13 GAX23701.1 - 0.12 12.4 1.0 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Pao retrotransposon peptidase Pkinase PF00069.25 GAX23702.1 - 8.8e-46 156.4 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23702.1 - 6.6e-23 81.3 0.0 1.3e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX23702.1 - 0.00015 21.8 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX23702.1 - 0.029 13.3 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 GAX23702.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ArfGap PF01412.18 GAX23703.1 - 7e-28 97.1 0.0 1e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ATPgrasp_Ter PF15632.6 GAX23704.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon EXS PF03124.14 GAX23705.1 - 1.9e-51 175.3 5.7 1.9e-51 175.3 5.7 2.0 2 1 0 2 2 2 1 EXS family PLAC8 PF04749.17 GAX23706.1 - 2e-10 41.6 17.8 3.7e-10 40.7 17.8 1.5 1 1 0 1 1 1 1 PLAC8 family Fip1 PF05182.13 GAX23707.1 - 1.3e-16 59.8 0.5 2.8e-16 58.8 0.5 1.6 1 0 0 1 1 1 1 Fip1 motif TFIID_30kDa PF03540.13 GAX23708.1 - 5.1e-06 26.3 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DUF179 PF02622.15 GAX23709.1 - 5.2e-16 59.0 0.0 2.5e-15 56.8 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 Complex1_LYR PF05347.15 GAX23709.1 - 0.58 10.3 3.1 4 7.6 0.2 2.9 3 0 0 3 3 3 0 Complex 1 protein (LYR family) SAC3_GANP PF03399.16 GAX23710.1 - 1.3e-70 238.1 0.0 9.3e-45 153.2 0.0 2.6 2 0 0 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAX23710.1 - 9e-06 25.7 0.1 2.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PAM2 PF07145.15 GAX23710.1 - 0.057 13.1 0.5 0.17 11.7 0.5 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Choline_transpo PF04515.12 GAX23711.1 - 5.5e-68 229.6 25.6 5.5e-68 229.6 25.6 2.7 1 1 1 2 2 2 2 Plasma-membrane choline transporter Cse1 PF08506.10 GAX23712.1 - 1.9e-123 412.0 0.1 7.4e-123 410.0 0.2 2.0 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 GAX23712.1 - 7e-110 367.5 0.9 1.3e-109 366.7 0.3 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 GAX23712.1 - 3.1e-12 46.2 0.0 2.2e-11 43.5 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAX23712.1 - 0.00063 19.8 4.0 0.0056 16.8 0.0 4.3 6 0 0 6 6 6 1 Exportin 1-like protein TAF6_C PF07571.13 GAX23712.1 - 0.087 13.2 0.7 10 6.5 0.1 3.9 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Peptidase_M16_M PF16187.5 GAX23713.1 - 8.3e-39 133.6 0.0 1.4e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX23713.1 - 4.3e-32 111.2 0.1 1e-30 106.7 0.1 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX23713.1 - 1.4e-21 77.4 0.0 6.1e-15 55.7 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain DS PF01916.17 GAX23714.1 - 1.2e-124 415.2 0.0 1.6e-124 414.8 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 GAX23714.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus LRR_8 PF13855.6 GAX23715.1 - 0.00059 19.6 0.3 0.0014 18.3 0.3 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GAX23715.1 - 0.00096 19.5 0.2 0.0022 18.4 0.2 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) OppC_N PF12911.7 GAX23715.1 - 0.016 15.2 0.1 0.035 14.1 0.1 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C LRR_1 PF00560.33 GAX23715.1 - 0.38 11.5 3.8 2.3 9.1 0.6 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat PH PF00169.29 GAX23716.1 - 3.5e-12 46.7 0.1 8.5e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAX23716.1 - 0.00062 20.0 0.1 0.0011 19.2 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAX23716.1 - 0.0023 18.3 1.4 0.071 13.5 1.4 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Ribosomal_L32p PF01783.23 GAX23716.1 - 0.15 12.3 0.7 0.53 10.6 0.7 1.9 1 0 0 1 1 1 0 Ribosomal L32p protein family PH_13 PF16652.5 GAX23716.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Prenylcys_lyase PF07156.14 GAX23717.1 - 2.9e-29 102.3 0.0 8.8e-16 58.0 0.0 2.5 2 1 0 2 2 2 2 Prenylcysteine lyase DAO PF01266.24 GAX23717.1 - 3.4e-06 26.9 0.1 2.3e-05 24.2 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX23717.1 - 0.00078 19.6 0.0 0.0021 18.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAX23717.1 - 0.048 13.7 0.1 6.1 6.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAX23717.1 - 0.053 12.7 0.1 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX23717.1 - 0.17 10.7 0.0 0.33 9.8 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase DUF1118 PF06549.12 GAX23718.1 - 8.6e-05 22.8 4.2 8.6e-05 22.8 4.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1118) UPF0020 PF01170.18 GAX23719.1 - 2.5e-10 40.4 0.7 1.4e-08 34.6 0.7 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 GAX23719.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.18 GAX23719.1 - 0.0047 16.7 0.0 0.65 9.7 0.0 2.3 2 0 0 2 2 2 2 DNA methylase Macoilin PF09726.9 GAX23720.1 - 2.8 6.4 6.1 3.7 6.0 6.1 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 GAX23721.1 - 2.2e-33 115.7 0.0 3.2e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23721.1 - 4.7e-13 49.0 0.0 7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SNF2_N PF00176.23 GAX23723.1 - 0.05 12.3 0.0 0.081 11.6 0.0 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain Brix PF04427.18 GAX23724.1 - 1.6e-25 90.3 0.0 2e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain ATP-synt_D PF01813.17 GAX23725.1 - 4.1e-60 203.0 0.2 5.1e-60 202.7 0.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D NDUF_B7 PF05676.13 GAX23726.1 - 1.6e-19 69.4 1.6 2e-19 69.1 1.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MRP-L46 PF11788.8 GAX23727.1 - 3.8e-06 27.6 10.1 5.7e-05 23.8 0.0 3.7 4 0 0 4 4 4 2 39S mitochondrial ribosomal protein L46 HAD_SAK_2 PF18143.1 GAX23727.1 - 0.074 13.4 0.6 0.35 11.2 0.0 2.2 1 1 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins UCH PF00443.29 GAX23728.1 - 2.2e-38 132.3 0.0 2.8e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAX23728.1 - 2.1e-09 37.6 0.3 4.7e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAX23728.1 - 0.011 15.3 0.2 0.021 14.4 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Methyltransf_11 PF08241.12 GAX23730.1 - 0.2 12.3 0.2 32 5.3 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain SET PF00856.28 GAX23731.1 - 9.1e-05 22.9 0.4 0.0063 16.9 0.0 2.8 2 2 0 2 2 2 2 SET domain DUF2118 PF09891.9 GAX23731.1 - 0.084 12.8 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) WD40 PF00400.32 GAX23732.1 - 5.8e-46 153.5 19.7 5.7e-06 27.0 0.1 8.1 7 1 1 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX23732.1 - 6.4e-11 42.4 0.2 0.015 15.6 0.0 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAX23732.1 - 0.0043 15.6 0.0 0.56 8.7 0.1 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 GAX23732.1 - 0.029 13.0 6.3 0.21 10.2 0.0 3.7 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX23732.1 - 0.073 12.0 0.2 4.1 6.3 0.0 2.9 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAX23732.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain DEAD PF00270.29 GAX23733.1 - 1.5e-37 129.0 0.1 4.2e-34 117.8 0.0 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX23733.1 - 2.3e-17 63.4 0.0 8.7e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX23733.1 - 2e-09 37.7 0.0 6.3e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAX23733.1 - 0.019 15.2 3.2 3.8 7.8 1.2 3.4 2 1 0 2 2 2 0 AAA domain DUF2937 PF11157.8 GAX23733.1 - 0.075 12.7 0.6 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Pkinase PF00069.25 GAX23734.1 - 9.4e-17 61.2 0.0 1.8e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23734.1 - 3.4e-16 59.3 0.0 5.8e-16 58.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 GAX23734.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 SAM_MT PF04445.13 GAX23735.1 - 1.5e-42 145.6 0.2 2.7e-42 144.8 0.2 1.4 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase STAG PF08514.11 GAX23736.1 - 5.4e-07 29.5 0.6 4.6e-06 26.5 0.0 3.0 3 0 0 3 3 3 1 STAG domain HEAT PF02985.22 GAX23736.1 - 1.2e-05 25.1 5.9 0.65 10.4 0.1 6.8 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 GAX23736.1 - 0.00077 19.5 6.8 0.019 15.0 0.0 4.2 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 GFO_IDH_MocA PF01408.22 GAX23737.1 - 9.5e-16 58.7 0.0 2.1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 GAX23737.1 - 0.002 18.2 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 GAX23737.1 - 0.0023 18.0 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 GAX23738.1 - 1.5e-47 162.2 0.6 1.9e-47 161.9 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX23738.1 - 7.3e-26 90.6 0.2 1.6e-25 89.5 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX23738.1 - 1.4e-12 48.0 0.1 4e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX23738.1 - 1.7e-05 24.1 0.5 4.4e-05 22.7 0.5 1.7 1 0 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.6 GAX23738.1 - 0.0016 17.7 0.1 0.014 14.5 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAX23738.1 - 0.018 13.7 1.2 3.1 6.4 0.2 3.1 2 1 0 3 3 3 0 HI0933-like protein 3HCDH_N PF02737.18 GAX23738.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 GAX23738.1 - 0.048 12.9 0.4 0.092 12.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX23738.1 - 8.2 5.4 10.8 0.18 10.9 1.7 2.6 3 1 0 3 3 3 0 FAD binding domain Pro_isomerase PF00160.21 GAX23740.1 - 1e-45 155.8 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 GAX23741.1 - 1.4e-50 172.1 0.0 1.4e-30 106.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23741.1 - 4.5e-25 88.4 0.0 2.5e-17 63.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAX23741.1 - 1.6e-05 24.4 1.0 0.0096 15.3 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 GAX23741.1 - 0.00046 19.6 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAX23741.1 - 0.0044 16.0 0.1 0.0091 15.0 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAX23741.1 - 0.021 14.7 0.1 0.12 12.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC_tran PF00005.27 GAX23742.1 - 2.8e-11 44.1 0.0 8.8e-10 39.2 0.0 2.5 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 GAX23742.1 - 1.5e-06 28.8 0.0 7.1e-06 26.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.19 GAX23742.1 - 7.9e-06 25.5 0.0 2.5e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX23742.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAX23742.1 - 0.0022 18.3 0.0 0.091 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 GAX23742.1 - 0.0038 16.1 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_21 PF13304.6 GAX23742.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAX23742.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 GAX23743.1 - 8.6e-05 23.1 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 GAX23743.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAX23743.1 - 0.027 14.5 0.7 0.047 13.8 0.7 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 GAX23743.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 GAX23743.1 - 0.045 13.8 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Dynamin family RsgA_GTPase PF03193.16 GAX23743.1 - 0.052 13.5 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase EPO_TPO PF00758.18 GAX23743.1 - 0.059 13.4 0.1 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin AAA_15 PF13175.6 GAX23743.1 - 0.062 13.0 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 GAX23743.1 - 0.08 13.3 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain UPF0240 PF06784.11 GAX23743.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) AAA_21 PF13304.6 GAX23743.1 - 0.17 11.7 0.3 0.31 10.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FAD_binding_7 PF03441.14 GAX23745.1 - 3.6e-74 248.6 1.4 5.4e-74 248.0 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAX23745.1 - 1.4e-27 96.8 0.0 2.4e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Ala_racemase_C PF00842.21 GAX23746.1 - 9.8e-32 109.4 0.1 2.1e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Ala_racemase_N PF01168.20 GAX23746.1 - 2.3e-31 109.1 0.7 5e-16 59.0 0.1 3.6 2 1 0 2 2 2 2 Alanine racemase, N-terminal domain Proteasom_PSMB PF10508.9 GAX23746.1 - 1.5e-15 56.8 0.7 6.1e-10 38.2 0.0 2.6 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 GAX23746.1 - 0.026 14.9 0.0 0.96 9.9 0.0 3.2 2 0 0 2 2 2 0 HEAT repeats ABC_tran PF00005.27 GAX23747.1 - 4.2e-45 153.6 0.0 6.1e-28 98.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAX23747.1 - 2.7e-40 138.7 30.7 2.8e-25 89.5 15.3 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAX23747.1 - 1.7e-10 40.7 4.0 0.00034 20.1 0.1 4.2 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX23747.1 - 6.2e-07 29.5 0.5 0.19 11.5 0.0 4.7 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAX23747.1 - 0.00037 20.6 0.3 0.029 14.5 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX23747.1 - 0.0026 17.5 0.4 0.7 9.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 GAX23747.1 - 0.0089 16.1 1.7 2.8 8.0 0.2 2.5 2 0 0 2 2 2 2 Dynamin family SbcCD_C PF13558.6 GAX23747.1 - 0.0091 16.2 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 GAX23747.1 - 0.0092 15.8 1.1 0.066 13.0 0.0 2.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 GAX23747.1 - 0.012 14.9 0.2 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 GAX23747.1 - 0.014 15.3 0.2 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAX23747.1 - 0.1 12.9 0.0 5.2 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 GAX23747.1 - 0.19 12.3 0.1 0.67 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Lysine_decarbox PF03641.14 GAX23748.1 - 3.7e-26 91.8 0.0 6.4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 GAX23748.1 - 5.6e-14 52.0 0.0 2.6e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 SLOG cluster4 family VPS13 PF16908.5 GAX23749.1 - 6.5e-34 117.7 0.0 2.1e-32 112.8 0.0 2.9 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 GAX23749.1 - 1.7e-18 66.8 0.3 4.2e-17 62.3 0.0 3.2 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 GAX23749.1 - 3.4e-12 46.3 0.0 6.4e-10 38.9 0.0 3.6 3 1 1 4 4 4 1 Repeating coiled region of VPS13 VPS13_C PF16909.5 GAX23749.1 - 0.0033 17.2 0.0 0.0033 17.2 0.0 3.5 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal Apt1 PF10351.9 GAX23749.1 - 0.032 13.1 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF-5_eIF-2B PF01873.17 GAX23750.1 - 6.1e-34 116.4 0.0 1.9e-33 114.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 GAX23750.1 - 2.2e-17 63.0 1.4 2.2e-17 63.0 1.4 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon AAA_11 PF13086.6 GAX23750.1 - 0.023 14.5 3.7 0.029 14.2 2.3 1.7 2 0 0 2 2 2 0 AAA domain DDHD PF02862.17 GAX23750.1 - 0.086 13.0 4.6 0.23 11.6 4.9 1.5 2 0 0 2 2 2 0 DDHD domain NCKAP5 PF15246.6 GAX23750.1 - 0.92 9.1 21.5 1.1 8.8 20.9 1.4 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein Zip PF02535.22 GAX23750.1 - 1.8 7.7 5.2 2.2 7.4 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2722 PF10846.8 GAX23750.1 - 5 6.0 14.5 8.7 5.2 14.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ALMT PF11744.8 GAX23750.1 - 7.4 5.3 6.9 11 4.7 6.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PTPRCAP PF15713.5 GAX23750.1 - 8.6 6.6 17.7 1.6 9.0 12.7 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Med19 PF10278.9 GAX23750.1 - 8.8 6.2 25.3 24 4.8 25.3 1.8 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 UQ_con PF00179.26 GAX23751.1 - 2.9e-40 137.2 0.0 3.2e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX23751.1 - 0.0064 16.2 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B CBFD_NFYB_HMF PF00808.23 GAX23752.1 - 2.3e-10 40.6 1.2 3.9e-10 39.9 0.3 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX23752.1 - 1.1e-05 25.7 0.9 1.5e-05 25.4 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SDA1 PF05285.12 GAX23752.1 - 0.036 13.5 16.4 0.037 13.5 16.4 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAX23752.1 - 0.28 9.4 10.9 0.3 9.3 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAX23752.1 - 2.1 6.4 21.6 2.7 6.1 21.6 1.1 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 GAX23752.1 - 2.3 6.7 7.4 2.3 6.7 7.4 1.0 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 GAX23752.1 - 3 7.1 22.0 4 6.7 22.0 1.2 1 0 0 1 1 1 0 BUD22 Peptidase_S64 PF08192.11 GAX23752.1 - 4.3 5.7 7.2 4.7 5.6 7.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 GAX23752.1 - 7.2 3.6 6.6 7.2 3.6 6.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Raftlin PF15250.6 GAX23752.1 - 8.2 5.0 7.7 11 4.7 7.7 1.1 1 0 0 1 1 1 0 Raftlin bZIP_1 PF00170.21 GAX23753.1 - 6.6e-10 39.0 6.1 1e-09 38.4 5.6 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX23753.1 - 1.1e-06 28.6 6.5 2.4e-06 27.5 6.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAX23753.1 - 0.0033 17.9 3.2 0.0072 16.8 3.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Rhodanese_C PF12368.8 GAX23754.1 - 3.6e-12 46.5 7.9 8.1e-12 45.3 7.9 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 GAX23754.1 - 9.9e-11 41.9 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GAX23754.1 - 1.4e-06 28.8 0.0 5.3e-06 26.9 0.0 2.1 2 1 0 2 2 2 1 Rhodanese-like domain RRM_1 PF00076.22 GAX23754.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GlcNAc-1_reg PF18440.1 GAX23754.1 - 0.052 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain HTH_ParB PF17762.1 GAX23754.1 - 0.58 10.0 2.3 12 5.8 0.0 2.9 3 0 0 3 3 3 0 HTH domain found in ParB protein Sel1 PF08238.12 GAX23755.1 - 1.8e-19 69.7 0.0 0.00031 21.3 0.0 5.5 5 0 0 5 5 5 4 Sel1 repeat GlutR_N PF05201.15 GAX23756.1 - 1.9e-40 138.0 0.1 3.9e-40 137.0 0.1 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 GAX23756.1 - 3.6e-32 111.3 0.0 9.9e-32 109.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 GAX23756.1 - 2e-23 82.6 2.7 2e-23 82.6 2.7 1.9 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain OCD_Mu_crystall PF02423.15 GAX23756.1 - 0.0011 18.0 0.0 0.0025 16.8 0.0 1.6 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 GAX23756.1 - 0.0018 18.8 0.0 0.0085 16.6 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent betaPIX_CC PF16523.5 GAX23756.1 - 0.0019 18.0 1.1 0.006 16.4 1.1 1.8 1 0 0 1 1 1 1 betaPIX coiled coil TPR_2 PF07719.17 GAX23757.1 - 3.5e-23 79.8 15.1 0.0012 18.8 0.2 10.0 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAX23757.1 - 7.3e-23 80.9 8.8 0.00017 22.0 0.0 6.4 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23757.1 - 6.8e-20 70.0 6.4 0.00088 19.0 0.0 8.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23757.1 - 5.8e-18 63.6 10.0 0.009 16.2 0.1 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAX23757.1 - 6.8e-17 60.7 26.6 0.00048 20.7 0.3 8.7 8 3 2 10 10 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23757.1 - 5e-12 46.0 18.2 0.14 12.5 0.0 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX23757.1 - 7.2e-12 44.8 6.3 0.0024 17.5 0.1 7.0 7 0 0 7 7 7 3 TPR repeat TPR_16 PF13432.6 GAX23757.1 - 2.3e-06 28.1 21.1 0.013 16.1 0.1 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23757.1 - 5.8e-06 26.0 13.8 0.65 10.2 0.4 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX23757.1 - 2.2e-05 24.6 16.9 7.5 6.9 0.1 7.0 6 1 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAX23757.1 - 6.7e-05 23.0 0.2 67 4.2 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX23757.1 - 0.00021 21.4 14.2 0.12 12.5 1.2 6.3 7 1 1 8 8 8 2 Tetratricopeptide repeat NRBF2_MIT PF17169.4 GAX23757.1 - 0.001 19.2 0.5 4.4 7.6 0.1 3.9 3 0 0 3 3 3 1 MIT domain of nuclear receptor-binding factor 2 TPR_6 PF13174.6 GAX23757.1 - 0.0021 18.6 10.3 80 4.2 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat PPR PF01535.20 GAX23757.1 - 0.0045 17.2 0.1 1.6 9.1 0.0 3.4 3 0 0 3 3 3 1 PPR repeat TPR_10 PF13374.6 GAX23757.1 - 0.017 15.0 2.0 2.2 8.3 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DXPR_C PF13288.6 GAX23757.1 - 0.082 13.2 0.5 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 DXP reductoisomerase C-terminal domain SHNi-TPR PF10516.9 GAX23757.1 - 0.09 12.2 0.1 5.8 6.5 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR PEP_mutase PF13714.6 GAX23758.1 - 5.3e-44 150.5 0.0 6.7e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAX23758.1 - 9.9e-13 47.4 0.1 1.3e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 GAX23758.1 - 0.001 18.5 0.0 0.0059 16.0 0.0 2.1 2 1 0 2 2 2 1 Ketopantoate hydroxymethyltransferase zf-MYND PF01753.18 GAX23759.1 - 1.9e-07 31.0 8.6 1.9e-07 31.0 8.6 2.0 2 0 0 2 2 2 1 MYND finger F-box PF00646.33 GAX23759.1 - 0.00021 21.0 0.2 0.00057 19.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAX23759.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 GAX23759.1 - 0.043 13.7 0.3 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 F-box PsbP PF01789.16 GAX23760.1 - 0.00011 22.3 0.0 0.00022 21.4 0.0 1.5 1 1 0 1 1 1 1 PsbP Aminotran_4 PF01063.19 GAX23761.1 - 1.6e-34 119.7 0.0 2.1e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV PPR_2 PF13041.6 GAX23763.1 - 8.6e-29 99.5 0.2 0.0002 21.5 0.0 13.5 11 4 3 14 14 14 5 PPR repeat family PPR_1 PF12854.7 GAX23763.1 - 1.9e-21 75.4 0.0 0.0066 16.1 0.0 12.1 11 1 0 11 11 11 4 PPR repeat PPR_3 PF13812.6 GAX23763.1 - 4.5e-21 74.7 0.0 0.0048 16.9 0.0 10.3 8 2 2 10 10 10 5 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX23763.1 - 1.6e-14 53.8 13.0 0.00097 18.6 0.1 6.1 3 3 5 8 8 8 7 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX23763.1 - 9.1e-13 47.5 17.1 0.061 13.6 0.0 13.0 15 0 0 15 15 15 3 PPR repeat E7 PF00527.18 GAX23763.1 - 0.0037 17.4 0.2 2.7 8.2 0.1 2.7 2 0 0 2 2 2 2 E7 protein, Early protein UPF0004 PF00919.20 GAX23763.1 - 0.0041 17.1 0.3 0.15 12.1 0.1 3.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 V-ATPase_H_N PF03224.14 GAX23763.1 - 0.034 13.4 0.0 0.14 11.5 0.0 2.0 1 1 1 2 2 2 0 V-ATPase subunit H RNA_pol_Rpb1_4 PF05000.17 GAX23763.1 - 0.11 12.5 0.1 38 4.3 0.0 3.3 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 4 PSY3 PF16836.5 GAX23763.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description RNA_pol_Rpc4 PF05132.14 GAX23765.1 - 0.11 13.0 1.1 0.31 11.4 1.1 1.9 1 0 0 1 1 1 0 RNA polymerase III RPC4 HXXSHH PF07586.11 GAX23765.1 - 0.2 11.2 2.8 0.38 10.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Insulin PF00049.18 GAX23765.1 - 0.5 11.4 1.6 4 8.5 0.0 2.9 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family RNA_polI_A34 PF08208.11 GAX23765.1 - 3.7 7.6 14.6 7.5 6.6 14.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1682 PF07946.14 GAX23765.1 - 5.2 6.2 20.8 1.9 7.6 16.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) CNDH2_C PF16858.5 GAX23767.1 - 0.076 12.9 2.0 0.16 11.9 2.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term NUDIX PF00293.28 GAX23768.1 - 3.2e-09 36.9 0.0 7.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Methyltransf_32 PF13679.6 GAX23768.1 - 7.3e-05 22.8 5.6 7.3e-05 22.8 5.6 2.8 3 1 0 3 3 3 1 Methyltransferase domain TPR_1 PF00515.28 GAX23769.1 - 0.02 14.7 0.1 2.8 7.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat E2F_TDP PF02319.20 GAX23770.1 - 3.5e-30 103.9 0.1 1.9e-17 63.1 0.1 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 GAX23770.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Mito_carr PF00153.27 GAX23771.1 - 0.007 16.3 1.5 3.8 7.5 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein NACHT PF05729.12 GAX23772.1 - 0.0012 18.8 0.9 0.0038 17.1 0.9 1.9 1 1 0 1 1 1 1 NACHT domain VGLL4 PF15245.6 GAX23772.1 - 0.073 13.1 1.4 0.21 11.6 1.3 1.8 1 1 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 T3SSipB PF16535.5 GAX23773.1 - 0.0047 17.4 1.6 0.0047 17.4 1.6 2.2 2 0 0 2 2 2 1 Type III cell invasion protein SipB DUF724 PF05266.14 GAX23773.1 - 0.45 10.3 12.7 2.4 7.9 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 GAX23773.1 - 5.3 6.2 12.0 0.58 9.4 3.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 GAX23773.1 - 6.2 7.4 29.2 0.077 13.5 4.9 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region Bac_globin PF01152.21 GAX23774.1 - 2.1e-08 34.3 0.1 3e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial-like globin SOBP PF15279.6 GAX23775.1 - 2.3 8.7 17.7 4.1 7.9 17.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_M16_C PF05193.21 GAX23778.1 - 1.8e-26 93.3 0.0 6.3e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAX23778.1 - 3.4e-20 72.5 0.0 4.5e-19 68.9 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DNA_pol_phi PF04931.13 GAX23779.1 - 1.2 7.1 6.3 1.6 6.7 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi ArsA_ATPase PF02374.15 GAX23780.1 - 7e-103 344.0 0.1 8.4e-91 304.3 0.0 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 GAX23780.1 - 7.2e-14 52.1 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX23780.1 - 9.1e-12 45.2 0.0 2.2e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 GAX23780.1 - 1.7e-06 27.7 0.1 1.2e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 GAX23780.1 - 7.6e-06 25.5 1.4 0.0014 18.2 0.2 2.9 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 GAX23780.1 - 0.00011 21.9 1.5 0.0078 15.9 0.2 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 GAX23780.1 - 0.0014 18.2 0.0 0.0044 16.5 0.0 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GAX23780.1 - 0.0082 15.7 0.1 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NAD_binding_9 PF13454.6 GAX23780.1 - 0.098 12.6 0.0 0.91 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding PhoH PF02562.16 GAX23780.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2868 PF11067.8 GAX23780.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) VirC1 PF07015.11 GAX23780.1 - 0.12 11.7 0.1 0.27 10.5 0.1 1.7 1 1 0 1 1 1 0 VirC1 protein NB-ARC PF00931.22 GAX23780.1 - 0.17 11.0 0.1 0.44 9.7 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain MipZ PF09140.11 GAX23780.1 - 0.26 10.6 0.7 2 7.7 0.1 2.1 1 1 1 2 2 2 0 ATPase MipZ BRE1 PF08647.11 GAX23781.1 - 0.0048 16.9 18.2 0.0048 16.9 18.2 5.3 4 1 1 5 5 5 1 BRE1 E3 ubiquitin ligase MSL1_dimer PF16801.5 GAX23781.1 - 0.22 11.3 3.0 3.1 7.6 0.7 3.2 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 TRAF_BIRC3_bd PF16673.5 GAX23781.1 - 1.9 8.3 16.4 0.82 9.5 0.3 4.2 4 1 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Chordopox_A13L PF05961.11 GAX23782.1 - 0.26 11.6 0.9 6.3 7.1 0.2 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Peptidase_M24 PF00557.24 GAX23783.1 - 3.7e-51 173.8 0.0 4.6e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAX23783.1 - 1.2e-21 76.7 0.1 3e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 GAX23783.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Thioredoxin PF00085.20 GAX23785.1 - 6.4e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin LRR_4 PF12799.7 GAX23786.1 - 1.7e-16 60.0 6.4 0.00011 22.5 0.1 4.6 5 0 0 5 5 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX23786.1 - 6.5e-15 54.7 9.7 1.5e-09 37.5 2.3 3.6 1 1 2 3 3 3 3 Leucine rich repeat Roc PF08477.13 GAX23786.1 - 7.4e-15 55.2 0.1 2.1e-13 50.5 0.1 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Trypsin_2 PF13365.6 GAX23786.1 - 8.7e-14 52.7 0.0 2.3e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain COR PF16095.5 GAX23786.1 - 1.2e-08 35.0 0.0 0.0022 17.8 0.0 3.2 3 0 0 3 3 3 2 C-terminal of Roc, COR, domain LRR_1 PF00560.33 GAX23786.1 - 6.1e-07 29.1 2.7 2.9 8.8 0.1 6.1 5 1 0 5 5 5 1 Leucine Rich Repeat Ras PF00071.22 GAX23786.1 - 3.3e-06 26.8 0.1 2.5e-05 23.9 0.1 2.2 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAX23786.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAX23786.1 - 0.0075 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 GAX23786.1 - 0.024 14.1 0.8 0.74 9.3 0.8 2.4 1 1 0 1 1 1 0 ADP-ribosylation factor family LRR_6 PF13516.6 GAX23786.1 - 0.043 13.9 9.5 67 3.9 0.1 5.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.6 GAX23786.1 - 0.051 13.1 1.9 0.86 9.1 0.1 2.7 1 1 2 3 3 3 0 Leucine-rich repeat Surfac_D-trimer PF09006.11 GAX23787.1 - 0.046 13.6 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Corona_nucleoca PF00937.18 GAX23788.1 - 0.18 10.8 1.0 0.33 9.9 1.0 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RNase_PH PF01138.21 GAX23789.1 - 3.4e-13 50.3 0.2 5.5e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Mog1 PF04603.12 GAX23790.1 - 7e-30 104.2 0.0 8.6e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Pkinase PF00069.25 GAX23791.1 - 1.7e-44 152.2 0.0 2.2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23791.1 - 6.1e-16 58.5 0.0 3.6e-15 56.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX23791.1 - 8.6e-05 22.6 0.0 0.00035 20.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX23791.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX23791.1 - 0.028 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 GAX23792.1 - 5.4e-41 140.7 0.0 7.7e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX23792.1 - 9.5e-20 71.0 0.0 4.2e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX23792.1 - 4e-05 23.7 0.0 8.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX23792.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX23792.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 GAX23792.1 - 0.023 13.6 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain KA1 PF02149.19 GAX23794.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Kinase associated domain 1 SRP19 PF01922.17 GAX23795.1 - 6.4e-24 84.7 1.0 1e-23 84.1 0.0 1.7 2 0 0 2 2 2 1 SRP19 protein TPR_MLP1_2 PF07926.12 GAX23796.1 - 0.0029 17.7 7.5 0.0029 17.7 7.5 4.9 1 1 4 5 5 5 3 TPR/MLP1/MLP2-like protein DUF1681 PF07933.14 GAX23797.1 - 2e-35 121.6 0.0 2.5e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) TAT_ubiq PF07706.12 GAX23797.1 - 0.14 12.4 0.7 0.62 10.3 0.3 2.2 2 0 0 2 2 2 0 Aminotransferase ubiquitination site PspA_IM30 PF04012.12 GAX23798.1 - 6.4e-08 32.5 13.0 9.9e-08 31.8 13.0 1.3 1 0 0 1 1 1 1 PspA/IM30 family MAD PF05557.13 GAX23798.1 - 0.0011 17.5 8.0 0.0016 16.9 8.0 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF1771 PF08590.10 GAX23798.1 - 0.0056 17.0 1.5 0.014 15.8 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) GCOM2 PF15328.6 GAX23798.1 - 0.0092 16.4 0.7 0.13 12.6 0.7 2.1 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 Gly-zipper_YMGG PF13441.6 GAX23798.1 - 0.039 13.7 13.2 0.068 12.9 13.2 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper FliD_N PF02465.18 GAX23798.1 - 0.065 13.9 5.2 0.38 11.5 1.3 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Laminin_II PF06009.12 GAX23798.1 - 0.099 12.7 4.1 5.4 7.0 0.2 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF5082 PF16888.5 GAX23798.1 - 0.48 10.7 5.8 1.4 9.2 3.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Romo1 PF10247.9 GAX23798.1 - 0.5 10.8 4.5 1.1 9.6 4.5 1.7 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 GrpE PF01025.19 GAX23798.1 - 1.3 8.6 7.3 1.9 8.1 7.3 1.3 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 GAX23798.1 - 1.4 8.8 8.5 2.9 7.7 1.0 3.3 2 1 1 3 3 3 0 Septum formation initiator kleA_kleC PF17383.2 GAX23798.1 - 1.5 9.2 4.6 1.1 9.7 1.1 2.2 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A Spc7 PF08317.11 GAX23798.1 - 2.4 6.9 9.9 3.8 6.3 9.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3593 PF12159.8 GAX23799.1 - 1.5e-30 105.1 3.7 1.6e-30 105.0 0.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3593) DUF2499 PF10693.9 GAX23799.1 - 6.9e-29 100.0 3.3 2.3e-28 98.3 3.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF5379 PF17350.2 GAX23799.1 - 0.064 13.5 0.8 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5379) zf-LYAR PF08790.11 GAX23800.1 - 0.71 9.8 4.7 19 5.2 0.3 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Herpes_LMP1 PF05297.11 GAX23800.1 - 3.4 6.8 7.6 4 6.5 0.9 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Myticin-prepro PF10690.9 GAX23800.1 - 4.7 7.5 7.4 41 4.5 1.9 3.9 3 1 1 4 4 4 0 Myticin pre-proprotein from the mussel DUF1499 PF07386.11 GAX23801.1 - 9.6e-22 77.7 0.0 2.1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Methyltr_RsmB-F PF01189.17 GAX23801.1 - 2e-19 70.0 0.1 7.1e-11 42.1 0.0 3.5 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 GAX23801.1 - 0.00012 21.9 0.0 0.035 13.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltr_RsmF_N PF17125.5 GAX23801.1 - 0.0049 17.3 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 GAX23801.1 - 0.0067 16.6 0.0 0.033 14.3 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 GAX23801.1 - 0.016 15.9 0.1 0.081 13.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 GAX23801.1 - 0.18 11.1 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PGI PF00342.19 GAX23802.1 - 1.6e-43 149.0 0.0 3e-32 111.9 0.0 3.9 2 1 0 2 2 2 2 Phosphoglucose isomerase Bromodomain PF00439.25 GAX23803.1 - 8.1e-10 38.6 0.0 2.5e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Bromodomain DUF4962 PF16332.5 GAX23803.1 - 0.063 11.8 0.8 0.11 11.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Pox_A11 PF05061.13 GAX23803.1 - 0.41 9.9 2.4 0.45 9.8 0.1 2.0 2 0 0 2 2 2 0 Poxvirus A11 Protein Guanylate_cyc PF00211.20 GAX23804.1 - 3.1e-44 150.8 0.0 5.8e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX23804.1 - 8.6e-33 114.0 0.3 1.6e-32 113.1 0.3 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Picorna_P3A PF06363.11 GAX23804.1 - 0.004 17.0 0.1 2.9 7.8 0.1 2.8 2 0 0 2 2 2 2 Picornaviridae P3A protein DUF4222 PF13973.6 GAX23804.1 - 0.2 11.3 0.4 0.61 9.7 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) Ank_4 PF13637.6 GAX23805.1 - 1.2e-08 35.3 0.3 0.00015 22.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX23805.1 - 2.4e-08 34.4 0.2 0.00058 20.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX23805.1 - 2.9e-08 33.3 0.5 0.027 15.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAX23805.1 - 9.1e-08 32.2 1.1 1.8e-05 24.9 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX23805.1 - 0.014 15.8 4.4 0.86 10.2 0.1 3.3 4 0 0 4 4 4 0 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 GAX23806.1 - 2.5e-17 63.6 0.0 4.8e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 GAX23806.1 - 0.016 15.5 0.0 0.05 13.9 0.0 1.7 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy PF03171.20 GAX23806.1 - 0.024 15.1 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAX23806.1 - 0.06 14.0 0.0 0.17 12.6 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Tautomerase PF01361.21 GAX23806.1 - 0.068 13.1 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme DAO PF01266.24 GAX23807.1 - 6.7e-14 52.2 5.9 1.1e-07 31.8 0.7 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX23807.1 - 1.1e-11 44.6 0.2 1.1e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX23807.1 - 2.9e-10 39.8 2.5 9.7e-07 28.2 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 GAX23807.1 - 1.4e-08 34.4 2.1 2e-08 33.9 0.8 1.9 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAX23807.1 - 5.9e-08 31.8 0.3 3e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAX23807.1 - 5.1e-07 29.2 0.8 8.6e-07 28.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX23807.1 - 5.9e-07 29.6 0.2 1.9e-06 28.0 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAX23807.1 - 2.7e-06 27.8 0.7 0.00069 20.1 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX23807.1 - 1e-05 24.9 1.4 0.00042 19.5 0.1 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 GAX23807.1 - 1.5e-05 24.4 0.1 0.0001 21.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 GAX23807.1 - 3e-05 23.5 0.2 0.069 12.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 GAX23807.1 - 0.00026 20.2 0.4 0.0015 17.6 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 GAX23807.1 - 0.0011 18.5 2.0 0.0032 16.9 0.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX23807.1 - 0.0013 18.8 3.1 0.43 10.6 0.2 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding ApbA PF02558.16 GAX23807.1 - 0.0014 18.3 0.1 0.0032 17.1 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 GAX23807.1 - 0.0048 16.4 0.1 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 GAX23807.1 - 0.0084 16.5 0.0 0.035 14.5 0.0 2.1 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 GAX23807.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 GAX23807.1 - 0.047 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 GAX23807.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 GAX23807.1 - 0.18 10.6 0.1 0.3 9.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase PRP1_N PF06424.12 GAX23810.1 - 1.1 9.6 5.2 0.36 11.2 1.3 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Pyr_redox_2 PF07992.14 GAX23811.1 - 2e-36 125.7 0.0 1.1e-35 123.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX23811.1 - 0.0002 21.8 0.0 0.006 17.1 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase APO_RNA-bind PF05634.11 GAX23812.1 - 0.068 12.5 1.3 0.12 11.7 1.3 1.3 1 0 0 1 1 1 0 APO RNA-binding SHMT PF00464.19 GAX23813.1 - 8.9e-49 166.1 0.0 1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase FliT PF05400.13 GAX23813.1 - 0.00016 22.4 0.8 0.11 13.3 0.3 2.1 2 0 0 2 2 2 2 Flagellar protein FliT Coat_F PF07875.12 GAX23813.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Coat F domain PqiA PF04403.13 GAX23814.1 - 2.3e-15 56.8 15.7 4.9e-08 32.9 2.4 2.7 2 0 0 2 2 2 2 Paraquat-inducible protein A KIX PF02172.16 GAX23815.1 - 0.0051 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 KIX domain Aa_trans PF01490.18 GAX23816.1 - 1.7e-35 122.5 16.6 1.3e-34 119.6 16.6 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GST_N_2 PF13409.6 GAX23818.1 - 2.6e-15 56.5 0.0 7.3e-15 55.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAX23818.1 - 2.7e-05 24.3 0.2 7.6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX23818.1 - 0.00024 21.2 0.0 0.0007 19.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX23818.1 - 0.00042 20.3 0.1 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAX23818.1 - 0.063 13.1 0.4 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PBP1_TM PF14812.6 GAX23818.1 - 4 7.9 8.7 0.32 11.4 2.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HMG_box PF00505.19 GAX23819.1 - 2.4e-08 34.3 4.9 3.6e-07 30.5 4.9 2.7 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX23819.1 - 1.4e-06 28.8 2.2 1.4e-06 28.8 2.2 3.1 3 1 0 3 3 3 1 HMG-box domain DUF2894 PF11445.8 GAX23819.1 - 0.013 16.0 1.3 0.013 16.0 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) DUF3987 PF13148.6 GAX23819.1 - 0.02 13.9 4.6 0.049 12.7 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Orf78 PF06024.12 GAX23820.1 - 0.0059 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) PT PF04886.12 GAX23820.1 - 0.054 13.0 0.1 0.054 13.0 0.1 5.1 3 1 0 3 3 3 0 PT repeat TMEM154 PF15102.6 GAX23820.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.8 2 1 1 3 3 3 0 TMEM154 protein family RFC1 PF08519.12 GAX23821.1 - 1.4e-37 129.2 0.0 3.2e-37 128.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 GAX23821.1 - 1.2e-14 54.8 0.0 2.8e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 GAX23821.1 - 7.6e-10 39.0 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 GAX23821.1 - 3.8e-08 33.5 0.0 5.3e-07 29.7 0.0 2.7 1 1 1 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 GAX23821.1 - 2.9e-05 24.2 0.0 7.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain PTCB-BRCT PF12738.7 GAX23821.1 - 3.6e-05 23.6 0.0 0.00013 21.9 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain AAA_16 PF13191.6 GAX23821.1 - 9.7e-05 22.8 0.0 0.00049 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 GAX23821.1 - 0.00032 20.5 0.0 0.0032 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAX23821.1 - 0.00036 20.3 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 GAX23821.1 - 0.00037 20.5 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX23821.1 - 0.00076 19.8 0.1 0.012 15.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 GAX23821.1 - 0.0012 19.1 0.1 0.0043 17.4 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain RNA_helicase PF00910.22 GAX23821.1 - 0.0013 19.0 0.0 0.0049 17.2 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.12 GAX23821.1 - 0.0056 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.15 GAX23821.1 - 0.0088 16.0 0.5 0.49 10.3 0.1 2.4 1 1 1 2 2 2 1 NTPase AAA_33 PF13671.6 GAX23821.1 - 0.014 15.5 0.0 0.077 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta PF06144.13 GAX23821.1 - 0.038 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_6 PF12774.7 GAX23821.1 - 0.042 12.8 0.0 0.083 11.8 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 GAX23821.1 - 0.057 14.0 0.3 0.31 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAX23821.1 - 0.063 13.3 0.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 GAX23821.1 - 0.43 10.3 5.5 0.74 9.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain PSP1 PF04468.12 GAX23823.1 - 3.4e-31 107.3 1.3 5.2e-31 106.8 1.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region HAS-barrel PF09378.10 GAX23823.1 - 0.028 14.6 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 HAS barrel domain HCO3_cotransp PF00955.21 GAX23824.1 - 1.4e-116 390.3 8.2 6.9e-59 200.0 0.1 2.0 1 1 1 2 2 2 2 HCO3- transporter family ABC_membrane_2 PF06472.15 GAX23825.1 - 5.1e-56 190.0 7.7 7.4e-56 189.5 7.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAX23825.1 - 3.3e-18 66.5 0.1 8.4e-18 65.2 0.0 1.8 2 0 0 2 2 1 1 ABC transporter SbmA_BacA PF05992.12 GAX23825.1 - 8e-15 55.1 7.7 3.3e-14 53.0 7.6 1.9 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_16 PF13191.6 GAX23825.1 - 1.6e-06 28.6 0.1 9.9e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_membrane PF00664.23 GAX23825.1 - 5.2e-05 23.0 6.4 0.00014 21.6 6.4 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.6 GAX23825.1 - 0.0017 18.6 0.5 0.012 15.8 0.1 2.5 2 1 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 GAX23825.1 - 0.0022 18.0 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GAX23825.1 - 0.0026 17.5 0.2 0.0054 16.5 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 GAX23825.1 - 0.003 17.5 0.1 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 GAX23825.1 - 0.0037 17.0 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAX23825.1 - 0.004 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAX23825.1 - 0.0094 15.7 0.1 0.3 10.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 GAX23825.1 - 0.017 15.6 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAX23825.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 GAX23825.1 - 0.032 13.7 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 GAX23825.1 - 0.033 13.8 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_S49 PF01343.18 GAX23825.1 - 0.041 13.8 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 SbcCD_C PF13558.6 GAX23825.1 - 0.052 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 GAX23825.1 - 0.075 13.5 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 GAX23825.1 - 0.081 12.3 0.1 0.59 9.5 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 GAX23825.1 - 0.081 13.5 0.4 0.77 10.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX23825.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX23825.1 - 0.11 12.6 0.2 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 GAX23825.1 - 0.13 11.6 0.3 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_27 PF13514.6 GAX23825.1 - 0.13 11.8 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAX23825.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 GAX23825.1 - 0.18 11.9 0.1 0.58 10.3 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Abhydrolase_9_N PF15420.6 GAX23825.1 - 7.2 6.6 6.8 0.77 9.7 2.1 1.7 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Gly_transf_sug PF04488.15 GAX23826.1 - 2.9e-09 37.4 0.0 7.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX23826.1 - 5.8e-07 29.2 0.0 8.3e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAX23827.1 - 1.3e-08 35.3 0.0 3.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX23827.1 - 1.8e-06 27.6 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAX23828.1 - 3.9e-08 33.8 0.0 1.3e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX23828.1 - 8.6e-06 25.3 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein PPR_2 PF13041.6 GAX23830.1 - 8.6e-18 64.3 0.4 6.8e-06 26.2 0.0 6.1 4 1 2 6 6 6 4 PPR repeat family PPR_3 PF13812.6 GAX23830.1 - 1.4e-16 60.3 0.0 5.8e-09 35.9 0.0 4.4 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 GAX23830.1 - 9.3e-08 31.8 3.7 4 7.9 0.0 6.6 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 GAX23830.1 - 2.3e-06 27.2 3.4 0.38 10.5 0.0 5.1 5 0 0 5 5 5 3 PPR repeat SAP PF02037.27 GAX23830.1 - 5.7e-05 22.8 0.9 0.00032 20.4 0.8 2.2 2 0 0 2 2 2 1 SAP domain Arena_glycoprot PF00798.18 GAX23830.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Arenavirus glycoprotein IBR PF01485.21 GAX23832.1 - 5.2e-20 71.4 40.6 1.8e-11 44.1 3.5 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 GAX23832.1 - 4.9e-07 29.5 29.6 3.6e-06 26.7 1.5 4.1 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX23832.1 - 1.6e-06 28.0 4.2 1.6e-06 28.0 4.2 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX23832.1 - 2.7e-06 27.6 6.2 2.7e-06 27.6 6.2 4.1 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 GAX23832.1 - 7.7e-05 22.5 6.0 7.7e-05 22.5 6.0 5.1 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX23832.1 - 0.00018 21.4 4.6 0.00018 21.4 4.6 4.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAX23832.1 - 0.0029 17.3 3.0 0.0029 17.3 3.0 4.5 4 1 1 5 5 5 1 RING-like zinc finger ArsA_ATPase PF02374.15 GAX23832.1 - 0.1 11.8 0.2 0.19 10.9 0.2 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase zf-piccolo PF05715.13 GAX23832.1 - 0.23 11.6 22.9 0.35 11.1 1.5 3.5 3 0 0 3 3 3 0 Piccolo Zn-finger zf-RING_4 PF14570.6 GAX23832.1 - 0.98 9.3 31.9 0.16 11.8 4.9 3.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Palm_thioest PF02089.15 GAX23833.1 - 5.6e-63 213.0 0.2 7e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase SRTM1 PF15872.5 GAX23834.1 - 0.027 14.6 0.0 0.071 13.3 0.0 1.7 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 SNARE_assoc PF09335.11 GAX23835.1 - 0.0027 18.2 7.0 0.014 15.9 3.5 2.7 1 1 1 2 2 2 2 SNARE associated Golgi protein HSF_DNA-bind PF00447.17 GAX23836.1 - 9.2e-14 51.8 0.3 1.8e-13 50.9 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding M11L PF11099.8 GAX23836.1 - 0.18 12.1 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator M11L like AAA_16 PF13191.6 GAX23837.1 - 1e-19 71.6 0.2 4e-19 69.6 0.2 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX23837.1 - 6.6e-07 29.7 1.2 2.9e-05 24.4 0.0 3.6 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAX23837.1 - 0.00072 19.5 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PhoH PF02562.16 GAX23837.1 - 0.00094 18.7 0.0 0.0026 17.3 0.0 1.8 2 1 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.22 GAX23837.1 - 0.0014 17.9 0.0 0.065 12.4 0.0 2.7 1 1 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 GAX23837.1 - 0.0025 18.1 0.9 8.8 6.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 GAX23837.1 - 0.009 15.9 4.0 0.35 10.8 4.0 2.8 1 1 0 1 1 1 1 NACHT domain T2SSE PF00437.20 GAX23837.1 - 0.043 12.9 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 GAX23837.1 - 0.06 13.1 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 GAX23837.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX23837.1 - 0.088 13.3 0.1 0.59 10.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 GAX23837.1 - 0.088 12.1 0.0 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 GAX23837.1 - 0.11 12.5 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX23837.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Potassium_chann PF11404.8 GAX23837.1 - 0.17 11.7 0.1 0.47 10.3 0.1 1.8 1 0 0 1 1 1 0 Potassium voltage-gated channel AAA_16 PF13191.6 GAX23838.1 - 3.8e-19 69.7 0.0 1.4e-18 67.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX23838.1 - 3.9e-05 23.9 0.0 0.00092 19.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAX23838.1 - 0.00013 22.0 0.0 0.00037 20.5 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GAX23838.1 - 0.0024 17.1 0.0 1.4 8.0 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain PRK PF00485.18 GAX23838.1 - 0.011 15.5 0.1 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 GAX23838.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 GAX23838.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX23838.1 - 0.017 15.6 0.5 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GAX23838.1 - 0.031 13.6 0.1 0.41 10.0 0.0 2.5 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 GAX23838.1 - 0.032 14.1 0.3 0.16 11.9 0.3 2.2 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 GAX23838.1 - 0.055 14.0 0.0 0.21 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAX23838.1 - 0.062 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 GAX23838.1 - 0.52 10.6 6.0 13 6.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_29 PF13555.6 GAX23838.1 - 0.91 9.3 2.9 0.42 10.4 0.2 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain Atx10homo_assoc PF09759.9 GAX23839.1 - 7e-07 29.2 1.2 0.015 15.3 0.0 2.5 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 GAX23839.1 - 0.0014 18.6 3.1 3.9 7.6 0.2 3.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 GAX23839.1 - 0.0015 18.5 1.1 0.0039 17.2 0.5 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central RICTOR_N PF14664.6 GAX23839.1 - 0.0067 15.5 0.1 0.015 14.3 0.1 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term TEX13 PF15186.6 GAX23839.1 - 0.2 11.3 2.0 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family 7tm_3 PF00003.22 GAX23840.1 - 1.6e-41 142.6 14.0 2.2e-41 142.1 14.0 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX23840.1 - 8.2e-16 58.3 0.0 9e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 Periplasmic binding protein domain DUF998 PF06197.13 GAX23840.1 - 0.0058 16.3 5.9 0.046 13.3 1.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF998) Thioredoxin_11 PF18078.1 GAX23841.1 - 0.0044 17.1 0.0 2.9 8.0 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin-like SNTX domain DUF3516 PF12029.8 GAX23841.1 - 0.066 12.3 0.0 5 6.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3516) Prismane PF03063.20 GAX23841.1 - 0.087 11.5 0.0 4.4 5.9 0.0 2.0 1 1 1 2 2 2 0 Prismane/CO dehydrogenase family FAM167 PF11652.8 GAX23841.1 - 0.11 12.9 0.0 19 5.8 0.0 2.4 2 0 0 2 2 2 0 FAM167 zf-Tim10_DDP PF02953.15 GAX23842.1 - 1.7e-12 46.8 0.3 2.6e-12 46.2 0.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PAS_9 PF13426.7 GAX23843.1 - 8e-08 32.5 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 GAX23843.1 - 9.8e-05 22.3 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_12 PF18095.1 GAX23843.1 - 0.0043 16.7 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 UPF0242 C-terminal PAS-like domain PAS_4 PF08448.10 GAX23843.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.6 1 1 0 1 1 1 0 PAS fold PAS_8 PF13188.7 GAX23843.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain Thioredoxin PF00085.20 GAX23844.1 - 1.1e-10 41.4 0.1 2.5e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX23844.1 - 0.067 13.5 0.0 0.35 11.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX23844.1 - 0.078 13.4 1.1 0.36 11.3 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain Pro_Al_protease PF02983.14 GAX23844.1 - 0.18 11.9 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 Alpha-lytic protease prodomain DUF1823 PF08853.11 GAX23845.1 - 9.9e-42 141.7 0.5 9.9e-42 141.7 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1823) FLYWCH_u PF16662.5 GAX23845.1 - 0.96 9.5 5.9 23 5.1 2.3 2.9 3 0 0 3 3 3 0 FLYWCH-type zinc finger-containing protein 1 PAP_assoc PF03828.19 GAX23846.1 - 1.4e-09 38.1 0.1 2.9e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAX23846.1 - 5.6e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAX23846.1 - 0.00066 19.7 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase KELK PF15796.5 GAX23846.1 - 0.75 10.3 5.3 0.43 11.1 1.5 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RACo_C_ter PF14574.6 GAX23847.1 - 0.063 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain HupE_UreJ_2 PF13795.6 GAX23847.1 - 0.11 12.2 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 HupE / UreJ protein GST_N_2 PF13409.6 GAX23849.1 - 4.7e-20 71.7 0.0 2.6e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX23849.1 - 4.1e-08 33.1 0.0 1.5e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX23849.1 - 1.8e-06 28.0 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX23849.1 - 0.00028 21.0 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX23849.1 - 0.0019 18.6 0.0 2.5 8.6 0.0 3.2 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain DDHD PF02862.17 GAX23851.1 - 7.2e-44 150.6 0.1 3.7e-43 148.3 0.1 2.1 1 1 0 1 1 1 1 DDHD domain DUF676 PF05057.14 GAX23851.1 - 0.18 11.3 0.7 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Solute_trans_a PF03619.16 GAX23852.1 - 1e-82 277.6 8.8 1.4e-82 277.2 8.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Apolipoprotein PF01442.18 GAX23852.1 - 0.034 14.0 3.2 0.064 13.1 3.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4293 PF14126.6 GAX23852.1 - 0.045 14.0 11.7 0.19 12.0 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Fzo_mitofusin PF04799.13 GAX23852.1 - 0.2 11.2 3.7 0.13 11.8 0.9 2.0 2 1 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 GAX23852.1 - 4.1 7.5 6.4 4.1 7.5 4.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Metallophos PF00149.28 GAX23853.1 - 9.4e-08 32.8 0.1 1.6e-05 25.5 0.2 3.4 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX23853.1 - 0.033 14.4 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain B12D PF06522.11 GAX23854.1 - 0.015 15.1 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit LRR_8 PF13855.6 GAX23856.1 - 9.9e-28 95.7 25.2 1.7e-05 24.5 0.2 7.3 5 2 1 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 GAX23856.1 - 1.7e-14 53.7 35.1 0.0044 17.4 0.5 8.7 1 1 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX23856.1 - 3.5e-11 42.0 16.3 7.1 7.6 0.1 10.7 11 1 1 12 12 12 5 Leucine Rich Repeat LRR_6 PF13516.6 GAX23856.1 - 4.5e-08 32.5 15.8 0.26 11.4 0.0 7.9 7 0 0 7 7 7 5 Leucine Rich repeat LRR_8 PF13855.6 GAX23857.1 - 3.2e-17 62.1 18.3 0.0003 20.5 4.7 6.5 4 2 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GAX23857.1 - 2.3e-15 56.4 17.4 0.014 15.8 0.0 6.0 4 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX23857.1 - 8.8e-06 25.6 16.8 17 6.4 0.1 9.4 9 1 1 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX23857.1 - 0.48 10.6 7.4 40 4.6 0.2 5.6 5 0 0 5 5 5 0 Leucine Rich repeat Gal4_dimer PF03902.13 GAX23858.1 - 0.087 13.0 0.0 0.49 10.6 0.0 2.4 2 1 0 2 2 2 0 Gal4-like dimerisation domain UPF0014 PF03649.13 GAX23859.1 - 4.4e-67 225.9 18.4 6.3e-67 225.5 18.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) ABC_tran PF00005.27 GAX23859.1 - 2.4e-21 76.7 0.0 4.3e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAX23859.1 - 0.0024 18.3 0.0 0.0085 16.5 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX23859.1 - 0.019 15.2 0.0 0.071 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX23859.1 - 0.029 14.9 0.0 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAX23859.1 - 0.035 13.8 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 GAX23859.1 - 0.036 12.9 0.0 0.27 10.0 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 GAX23859.1 - 0.055 13.2 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 GAX23859.1 - 0.06 13.2 3.2 0.68 9.7 0.0 2.8 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAX23859.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Methyltransf_31 PF13847.6 GAX23860.1 - 1.7e-13 50.6 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX23860.1 - 2.3e-13 50.3 0.0 3.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX23860.1 - 1.1e-12 48.4 0.0 5.1e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX23860.1 - 1.6e-12 48.0 0.0 3.3e-12 47.0 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX23860.1 - 3.9e-11 43.5 0.0 9.1e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX23860.1 - 2.4e-08 33.7 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAX23860.1 - 1e-05 25.2 0.1 1.9e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 GAX23860.1 - 0.00015 20.9 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 GAX23860.1 - 0.00019 21.2 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.16 GAX23860.1 - 0.0008 18.6 0.0 0.001 18.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_32 PF13679.6 GAX23860.1 - 0.001 19.1 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAX23860.1 - 0.0016 18.6 0.1 0.0034 17.5 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAX23860.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 GAX23860.1 - 0.0024 16.8 0.1 0.0033 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 GAX23860.1 - 0.033 13.6 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.12 GAX23860.1 - 0.041 13.5 0.5 0.086 12.4 0.5 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 GAX23860.1 - 0.07 12.4 0.1 0.094 12.0 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.11 GAX23860.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 GAX23860.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB AID PF18767.1 GAX23861.1 - 0.088 12.8 0.0 7.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Activation induced deaminase HMG_box PF00505.19 GAX23862.1 - 2.4e-31 108.0 14.4 3e-16 59.6 1.4 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX23862.1 - 1.5e-21 76.8 12.6 1.5e-10 41.5 1.8 3.2 3 0 0 3 3 3 2 HMG-box domain SRTM1 PF15872.5 GAX23862.1 - 0.027 14.6 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 DUF2384 PF09722.10 GAX23862.1 - 0.043 13.9 0.2 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) Calici_MSP PF05752.11 GAX23862.1 - 1.3 8.9 0.0 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Calicivirus minor structural protein Cas9_PI2 PF18070.1 GAX23862.1 - 2.4 8.9 6.1 15 6.4 1.1 2.4 2 0 0 2 2 2 0 CRISPR-Cas9 PI domain Aldedh PF00171.22 GAX23863.1 - 5.7e-125 417.4 0.0 7.2e-125 417.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TFIIA_gamma_N PF02268.16 GAX23864.1 - 0.056 13.5 0.0 0.15 12.1 0.0 1.7 1 1 1 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Hid1 PF12722.7 GAX23864.1 - 0.11 10.6 5.7 0.14 10.3 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UBA PF00627.31 GAX23864.1 - 0.94 9.5 0.0 0.94 9.5 0.0 2.5 3 0 0 3 3 3 0 UBA/TS-N domain TetR_C_24 PF17932.1 GAX23864.1 - 1.9 8.8 6.2 0.5 10.6 0.3 2.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Aldedh PF00171.22 GAX23865.1 - 1.8e-118 396.0 1.2 2.1e-118 395.8 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phage_int_SAM_4 PF13495.6 GAX23867.1 - 0.052 14.0 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain TF_Zn_Ribbon PF08271.12 GAX23867.1 - 0.06 12.9 2.7 0.13 11.8 2.7 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RRN7 PF11781.8 GAX23867.1 - 0.32 10.7 4.1 0.65 9.7 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Histone_H2A_C PF16211.5 GAX23868.1 - 2.8e-20 71.8 1.4 6.2e-20 70.6 1.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAX23868.1 - 2.1e-14 54.0 0.0 2.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX23868.1 - 0.0035 17.6 0.0 0.0045 17.2 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Na_H_Exchanger PF00999.21 GAX23869.1 - 3.6e-47 161.0 36.4 5e-47 160.5 36.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EF-hand_7 PF13499.6 GAX23869.1 - 1.1e-15 57.9 0.6 6.7e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAX23869.1 - 3.4e-15 54.4 2.6 1.4e-05 24.3 0.0 3.6 3 0 0 3 3 3 3 EF hand TrkA_N PF02254.18 GAX23869.1 - 3.5e-15 56.3 0.0 1.1e-14 54.6 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain EF-hand_6 PF13405.6 GAX23869.1 - 8e-14 50.3 0.7 3.4e-05 23.4 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GAX23869.1 - 9.2e-14 50.2 2.8 1.2e-06 27.7 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAX23869.1 - 1.8e-09 37.3 1.6 0.0015 18.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAX23869.1 - 0.0097 16.2 0.1 0.034 14.5 0.0 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Glyco_transf_7C PF02709.14 GAX23870.1 - 6.4e-22 77.0 0.2 1.4e-21 76.0 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 GAX23870.1 - 2.6e-19 69.2 0.0 4.3e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 WW PF00397.26 GAX23870.1 - 1.1e-08 35.0 1.7 2.6e-08 33.8 1.7 1.7 1 0 0 1 1 1 1 WW domain NYN PF01936.18 GAX23870.1 - 0.056 13.9 0.1 0.12 12.8 0.1 1.6 1 1 0 1 1 1 0 NYN domain CHGN PF05679.16 GAX23870.1 - 0.098 11.5 0.0 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Chondroitin N-acetylgalactosaminyltransferase Ank_2 PF12796.7 GAX23871.1 - 1.9e-22 79.7 0.2 4.2e-08 33.7 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX23871.1 - 1.1e-14 54.6 0.1 0.00015 22.3 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX23871.1 - 7.6e-13 47.4 0.1 0.49 11.1 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 GAX23871.1 - 3.2e-09 36.9 0.6 0.0011 19.2 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX23871.1 - 5.5e-09 36.1 0.3 3.3 8.3 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat DnaJ PF00226.31 GAX23872.1 - 1e-20 73.6 0.1 8.7e-20 70.6 0.0 2.7 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.7 GAX23872.1 - 1e-07 32.1 5.2 1.1e-07 32.0 3.5 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAX23872.1 - 5.6e-07 29.7 4.9 1.2e-06 28.6 4.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAX23872.1 - 6e-05 23.3 3.1 0.00025 21.3 2.0 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 GAX23872.1 - 0.011 15.9 3.7 0.028 14.5 3.7 1.7 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_4 PF13894.6 GAX23872.1 - 0.014 16.1 1.3 0.04 14.8 1.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAX23872.1 - 0.36 11.4 2.7 0.87 10.2 2.7 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type PDEase_I PF00233.19 GAX23873.1 - 2.5e-33 115.8 0.1 3.9e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 GAX23873.1 - 4.4e-21 75.3 0.0 9.3e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.13 GAX23874.1 - 0.0021 18.0 0.1 0.26 11.2 0.0 2.6 2 0 0 2 2 2 2 CHASE domain Tmemb_9 PF05434.11 GAX23874.1 - 0.05 13.5 0.5 0.11 12.4 0.3 1.7 2 0 0 2 2 2 0 TMEM9 Podoplanin PF05808.11 GAX23874.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Podoplanin zf-MYND PF01753.18 GAX23876.1 - 3.3e-12 46.3 17.6 3.4e-12 46.2 14.8 2.0 1 1 1 2 2 2 1 MYND finger zf-Mss51 PF13824.6 GAX23876.1 - 0.0075 16.3 6.8 0.013 15.6 6.8 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 GAX23876.1 - 0.011 15.6 4.9 0.018 14.9 4.9 1.3 1 0 0 1 1 1 0 HIT zinc finger TerB PF05099.13 GAX23876.1 - 0.038 13.9 0.2 0.071 13.1 0.2 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TerB Sod_Cu PF00080.20 GAX23877.1 - 1.5e-36 125.7 1.3 1.8e-36 125.4 1.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) GTP_EFTU PF00009.27 GAX23878.1 - 3.6e-57 193.1 0.2 4.7e-57 192.7 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAX23878.1 - 1.1e-28 99.8 0.0 2.1e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAX23878.1 - 2e-16 60.1 2.3 4.8e-16 58.9 2.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX23878.1 - 0.00013 22.0 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 GAX23878.1 - 0.0023 17.5 0.1 0.0075 15.9 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAX23878.1 - 0.011 15.5 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 GAX23878.1 - 0.019 14.8 0.1 0.047 13.6 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 GAX23878.1 - 0.12 12.1 0.2 18 5.0 0.0 2.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_S8 PF00410.19 GAX23878.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 Vps39_1 PF10366.9 GAX23878.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Ribosomal_L7Ae PF01248.26 GAX23879.1 - 2.2e-22 78.6 0.2 7.5e-22 76.9 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 GAX23879.1 - 0.012 15.6 0.6 0.055 13.5 0.5 2.0 1 1 1 2 2 2 0 RNase P subunit Pop3 Ank_2 PF12796.7 GAX23880.1 - 2.5e-17 63.3 0.1 8.2e-14 52.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX23880.1 - 2.7e-16 58.0 0.1 0.00019 21.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 GAX23880.1 - 6.2e-12 45.4 0.3 3.7e-05 24.0 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 GAX23880.1 - 1.3e-11 44.8 0.0 2.1e-06 28.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 GAX23880.1 - 3.1e-11 43.2 16.2 5.3e-11 42.4 16.2 1.4 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.6 GAX23880.1 - 1.1e-07 31.9 0.3 1.1e-06 28.8 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) zf-HIT PF04438.16 GAX23880.1 - 0.00017 21.4 3.5 0.0003 20.6 3.5 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.6 GAX23880.1 - 0.7 10.0 7.3 1.5 9.0 7.3 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ank_2 PF12796.7 GAX23881.1 - 2.1e-15 57.1 0.0 3.1e-08 34.1 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX23881.1 - 1.6e-13 49.5 0.1 0.018 15.5 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat zf-MYND PF01753.18 GAX23881.1 - 4.2e-10 39.5 16.4 8.4e-10 38.6 16.4 1.5 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 GAX23881.1 - 4.4e-09 36.7 0.0 4.5e-07 30.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX23881.1 - 1.2e-07 31.8 0.0 0.017 15.5 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat zf-HIT PF04438.16 GAX23881.1 - 3e-07 30.2 6.4 5.2e-07 29.4 6.4 1.4 1 0 0 1 1 1 1 HIT zinc finger Ank_5 PF13857.6 GAX23881.1 - 4.5e-06 26.8 0.0 0.00015 22.0 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) zf-Mss51 PF13824.6 GAX23881.1 - 0.036 14.2 6.4 0.064 13.4 6.4 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 NEMO PF11577.8 GAX23883.1 - 0.0037 17.3 7.4 0.011 15.7 7.2 2.0 1 1 0 1 1 1 1 NF-kappa-B essential modulator NEMO ZapB PF06005.12 GAX23883.1 - 0.0081 16.6 3.0 0.018 15.5 3.0 1.5 1 0 0 1 1 1 1 Cell division protein ZapB PRKG1_interact PF15898.5 GAX23883.1 - 0.018 15.9 4.4 0.055 14.4 4.4 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4988 PF16378.5 GAX23883.1 - 0.03 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function SKA2 PF16740.5 GAX23883.1 - 0.036 13.9 1.5 0.082 12.7 1.5 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 UPF0029 PF01205.19 GAX23883.1 - 0.08 13.3 0.4 0.16 12.3 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Ax_dynein_light PF10211.9 GAX23883.1 - 0.083 12.8 6.7 0.16 11.9 6.7 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Phage_Nu1 PF07471.12 GAX23883.1 - 0.15 11.8 2.3 0.23 11.2 0.9 1.9 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Comm PF15957.5 GAX23883.1 - 0.15 12.4 0.9 0.36 11.2 0.1 2.0 2 1 0 2 2 2 0 Commissureless Spc24 PF08286.11 GAX23883.1 - 0.23 11.7 3.1 0.48 10.7 3.1 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Com_YlbF PF06133.11 GAX23883.1 - 0.24 12.0 4.4 0.56 10.8 4.4 1.5 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA HAUS6_N PF14661.6 GAX23883.1 - 0.59 9.7 6.8 1 8.9 6.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Csm1_N PF18504.1 GAX23883.1 - 0.67 10.3 4.6 1.3 9.5 4.0 1.8 1 1 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 GAX23883.1 - 1.4 8.8 6.7 0.2 11.5 1.5 2.1 1 1 1 2 2 2 0 Septum formation initiator GrpE PF01025.19 GAX23883.1 - 3.7 7.2 7.0 6.4 6.4 7.0 1.3 1 0 0 1 1 1 0 GrpE CCT PF06203.14 GAX23885.1 - 9.8e-16 57.5 14.6 9.8e-16 57.5 14.6 1.7 2 0 0 2 2 2 1 CCT motif TT_ORF2 PF02957.15 GAX23886.1 - 1.1 10.2 9.4 2.1 9.3 0.2 4.2 4 0 0 4 4 4 0 TT viral ORF2 Ion_trans PF00520.31 GAX23887.1 - 2.5e-12 46.6 14.8 2.5e-12 46.6 14.8 2.3 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 GAX23887.1 - 0.00038 19.2 12.5 0.00038 19.2 12.5 3.2 3 1 0 3 3 3 1 Polycystin cation channel DUF3339 PF11820.8 GAX23887.1 - 0.038 14.2 0.2 0.038 14.2 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3339) EamA PF00892.20 GAX23888.1 - 3.9e-23 82.1 23.5 9.1e-13 48.6 11.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 GAX23888.1 - 0.00033 20.3 1.8 0.00081 19.0 1.7 1.6 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter SLC35F PF06027.12 GAX23888.1 - 0.026 14.1 6.5 0.03 13.8 2.4 2.2 1 1 1 2 2 2 0 Solute carrier family 35 EamA PF00892.20 GAX23889.1 - 2.3e-22 79.7 25.3 1.5e-12 47.8 9.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 GAX23889.1 - 0.46 9.9 6.1 0.33 10.4 4.3 1.7 1 1 1 2 2 2 0 Solute carrier family 35 EamA PF00892.20 GAX23890.1 - 8e-25 87.6 20.1 3.8e-14 53.0 5.1 2.6 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 GAX23890.1 - 0.034 13.7 0.8 0.13 11.8 0.3 1.9 1 1 1 2 2 2 0 Solute carrier family 35 EamA PF00892.20 GAX23891.1 - 3.8e-27 95.1 16.8 7.2e-15 55.4 2.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX23891.1 - 0.0004 19.7 3.6 0.012 14.9 0.1 2.2 1 1 0 2 2 2 2 Purine nucleobase transmembrane transport SLC35F PF06027.12 GAX23891.1 - 0.0013 18.4 2.6 0.015 14.8 1.3 2.7 1 1 2 3 3 3 1 Solute carrier family 35 TPT PF03151.16 GAX23891.1 - 0.037 13.4 4.6 0.89 8.8 0.3 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family Glyco_tranf_2_4 PF13704.6 GAX23892.1 - 2.7e-05 24.6 4.1 8.8e-05 22.9 4.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 K_oxygenase PF13434.6 GAX23893.1 - 4e-17 62.4 0.0 1.7e-12 47.1 0.0 3.2 2 2 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAX23893.1 - 1.1e-12 47.8 0.0 1.5e-08 34.3 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX23893.1 - 4.4e-07 29.5 0.0 0.01 15.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX23893.1 - 4.6e-06 26.7 3.0 0.008 16.2 0.7 4.0 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAX23893.1 - 0.0028 18.2 0.0 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX23893.1 - 0.0029 17.8 0.0 0.5 10.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX23893.1 - 0.066 12.3 0.0 2.7 7.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 GAX23893.1 - 0.07 12.7 0.0 56 3.2 0.0 3.6 3 1 1 4 4 4 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAX23893.1 - 0.53 9.6 2.3 5.5 6.2 0.5 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HECT PF00632.25 GAX23894.1 - 1.7e-10 40.9 0.2 5.5e-08 32.7 0.0 2.4 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) GST_N PF02798.20 GAX23895.1 - 5.6e-08 33.0 0.0 2e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAX23895.1 - 1.7e-05 25.1 0.0 3.7e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAX23895.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAX23895.1 - 0.00093 19.9 0.0 0.0025 18.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 GAX23895.1 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAX23895.1 - 0.0018 18.6 0.0 0.0041 17.4 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_2 PF13409.6 GAX23895.1 - 0.0022 18.2 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TPR_12 PF13424.6 GAX23896.1 - 1.1e-14 54.4 28.7 2.3e-06 27.8 3.8 8.0 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX23896.1 - 1.8e-08 33.8 12.7 0.0014 18.6 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.22 GAX23896.1 - 2.9e-08 33.2 0.0 8.1e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 GAX23896.1 - 5.5e-08 32.4 18.4 0.0032 17.3 3.4 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23896.1 - 0.00036 20.2 4.5 0.42 10.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23896.1 - 0.002 18.2 3.9 1.3 9.4 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23896.1 - 0.0047 16.9 8.4 0.074 13.1 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF627 PF04781.12 GAX23896.1 - 0.0078 16.2 4.3 3.2 7.8 0.3 4.0 3 0 0 3 3 3 1 Protein of unknown function (DUF627) Ras PF00071.22 GAX23896.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Ras family HXXEE PF13787.6 GAX23896.1 - 0.093 13.5 0.1 2.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif TPR_14 PF13428.6 GAX23896.1 - 0.67 10.9 22.0 5.8 8.0 0.0 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX23896.1 - 8.8 6.0 11.9 2.8 7.6 7.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain zf-MYND PF01753.18 GAX23897.1 - 6e-10 39.1 18.8 6e-10 39.1 18.8 2.7 2 1 0 2 2 1 1 MYND finger zf-RING_2 PF13639.6 GAX23897.1 - 5.6e-08 33.0 4.9 5.6e-08 33.0 4.9 2.4 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAX23897.1 - 2.4e-06 27.3 5.8 2.4e-06 27.3 5.8 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX23897.1 - 6.8e-06 26.0 1.3 6.8e-06 26.0 1.3 2.3 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX23897.1 - 8.3e-06 25.6 5.2 8.3e-06 25.6 5.2 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX23897.1 - 1.9e-05 24.5 6.2 1.9e-05 24.5 6.2 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX23897.1 - 0.00035 20.6 2.1 0.00035 20.6 2.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAX23897.1 - 0.007 16.2 4.5 0.007 16.2 4.5 2.3 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C6H2 PF15801.5 GAX23897.1 - 0.023 15.0 14.5 0.023 15.0 14.5 2.7 3 1 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding TPR_9 PF13371.6 GAX23897.1 - 0.025 14.7 0.1 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 GAX23897.1 - 0.14 12.0 5.4 0.39 10.5 5.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger PI3_PI4_kinase PF00454.27 GAX23898.1 - 6.6e-28 98.2 0.1 1.5e-25 90.5 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SDA1 PF05285.12 GAX23899.1 - 2.6e-46 158.7 34.1 2.6e-46 158.7 34.1 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 GAX23899.1 - 2.7e-05 24.4 0.1 6.4e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 NUC130/3NT domain Phage_GPD PF05954.11 GAX23900.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Organ_specific PF10950.8 GAX23900.1 - 0.045 14.5 0.2 0.076 13.7 0.2 1.4 1 0 0 1 1 1 0 Organ specific protein DUF3886 PF13025.6 GAX23900.1 - 2.3 8.5 9.4 0.12 12.5 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Dus PF01207.17 GAX23901.1 - 8e-55 186.1 0.0 1.8e-52 178.4 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GAX23901.1 - 0.0026 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 GAX23901.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.17 GAX23901.1 - 0.028 13.7 0.0 0.067 12.5 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase G3P_antiterm PF04309.12 GAX23901.1 - 0.09 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator HalX PF08663.10 GAX23901.1 - 0.45 10.9 1.6 5.8 7.3 0.1 2.6 2 1 1 3 3 3 0 HalX domain HATPase_c PF02518.26 GAX23902.1 - 6.8e-25 87.8 0.1 1.4e-23 83.5 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX23902.1 - 8.1e-24 83.9 0.2 2.2e-23 82.5 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX23902.1 - 2e-13 50.2 0.0 1.1e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX23902.1 - 0.0012 18.7 0.0 0.0039 17.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bZIP_2 PF07716.15 GAX23902.1 - 0.011 15.8 1.7 0.025 14.7 1.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF1192 PF06698.11 GAX23902.1 - 0.037 14.1 0.6 0.14 12.3 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF1690 PF07956.11 GAX23902.1 - 0.048 14.1 3.5 0.23 11.9 0.2 2.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) TSC22 PF01166.18 GAX23902.1 - 0.092 13.1 0.7 0.25 11.7 0.7 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 GAX23902.1 - 0.094 12.8 2.9 0.26 11.4 2.9 1.7 1 0 0 1 1 1 0 bZIP transcription factor Glyco_hydro_20 PF00728.22 GAX23903.1 - 3.2e-100 336.0 0.9 1.2e-99 334.1 0.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAX23903.1 - 2.8e-09 37.8 0.0 6.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAX23903.1 - 1.5e-08 35.5 0.0 3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Capsid-VNN PF11729.8 GAX23903.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 nodavirus capsid protein FMN_red PF03358.15 GAX23904.1 - 8.2e-24 84.1 0.0 1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAX23904.1 - 1.2e-05 25.2 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold TPR_2 PF07719.17 GAX23905.1 - 1e-11 44.0 1.7 0.01 15.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23905.1 - 0.00018 21.2 0.8 7.2 6.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX23905.1 - 0.00078 20.0 1.5 0.16 12.6 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX23905.1 - 0.0064 16.8 3.0 4.5 7.6 0.3 3.2 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX23905.1 - 0.026 15.3 1.6 22 6.2 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23905.1 - 0.034 14.8 6.8 0.58 10.9 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX23905.1 - 0.051 13.8 0.9 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAX23905.1 - 0.12 12.7 0.6 14 6.2 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX23905.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.3 3 0 0 3 3 3 0 TPR repeat Use1 PF09753.9 GAX23906.1 - 8.1e-05 22.5 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2207 PF09972.9 GAX23906.1 - 0.029 13.2 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rootletin PF15035.6 GAX23906.1 - 0.047 13.7 4.3 0.12 12.4 4.3 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Syntaxin-6_N PF09177.11 GAX23906.1 - 0.049 14.2 0.7 0.12 12.9 0.2 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal T2SSF PF00482.23 GAX23906.1 - 0.091 12.7 2.0 0.29 11.1 1.9 2.1 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Wbp11 PF09429.10 GAX23906.1 - 0.29 11.5 3.1 0.15 12.5 0.8 1.7 2 0 0 2 2 2 0 WW domain binding protein 11 SNARE PF05739.19 GAX23906.1 - 1.2 9.2 5.5 0.26 11.3 0.4 2.6 3 1 0 3 3 3 0 SNARE domain EMC3_TMCO1 PF01956.16 GAX23907.1 - 3.3e-10 40.0 0.1 8.4e-10 38.6 0.1 1.6 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like CENP-Q PF13094.6 GAX23907.1 - 0.0046 17.2 0.2 0.0051 17.0 0.2 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SNAD4 PF18750.1 GAX23907.1 - 0.031 14.4 0.4 5.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF719 PF05334.13 GAX23907.1 - 0.2 11.8 2.8 0.3 11.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) VSG_B PF13206.6 GAX23907.1 - 0.34 10.1 5.1 0.44 9.8 5.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain LSM PF01423.22 GAX23908.1 - 8.8e-16 57.4 0.4 1.1e-15 57.1 0.4 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAX23908.1 - 0.0082 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Hfq protein ubiquitin PF00240.23 GAX23910.1 - 1.3e-05 24.9 1.9 2.7e-05 23.8 0.5 2.2 2 0 0 2 2 2 1 Ubiquitin family UN_NPL4 PF11543.8 GAX23910.1 - 0.012 16.0 0.7 0.12 12.9 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Vps51 PF08700.11 GAX23910.1 - 0.022 14.8 0.9 0.066 13.3 0.5 2.0 2 0 0 2 2 2 0 Vps51/Vps67 CTNNBL PF08216.11 GAX23910.1 - 0.065 13.4 0.8 0.17 12.1 0.5 1.8 1 1 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Syntaxin_2 PF14523.6 GAX23910.1 - 7.5 7.0 8.5 3.1e+02 1.8 8.5 2.9 1 1 0 1 1 1 0 Syntaxin-like protein Peptidase_M16_M PF16187.5 GAX23911.1 - 1.2e-61 208.5 0.1 2.2e-61 207.6 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX23911.1 - 3.7e-32 111.4 0.0 6.5e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX23911.1 - 1.3e-27 97.0 0.0 4.3e-19 69.2 0.0 3.7 4 1 0 4 4 4 2 Peptidase M16 inactive domain PNP_UDP_1 PF01048.20 GAX23912.1 - 6.8e-44 149.9 0.2 8.2e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily MGDG_synth PF06925.11 GAX23913.1 - 5.5e-23 81.9 0.0 9.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 GAX23913.1 - 6.7e-16 58.7 0.0 1.1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 GAX23913.1 - 5.5e-10 39.0 0.0 9.2e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX23913.1 - 1.4e-08 35.3 0.1 3.1e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PRMT5 PF05185.16 GAX23913.1 - 0.05 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TPP_enzyme_C PF02775.21 GAX23913.1 - 0.056 13.2 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MORN PF02493.20 GAX23915.1 - 1.7e-15 55.9 35.6 1.4e-05 24.7 0.4 7.1 7 0 0 7 7 7 4 MORN repeat TFIIE_beta PF02186.15 GAX23915.1 - 1.6 9.0 9.4 0.22 11.8 0.7 2.6 2 0 0 2 2 2 0 TFIIE beta subunit core domain Thioredoxin_12 PF18400.1 GAX23916.1 - 0.081 12.8 1.0 0.16 11.8 1.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Cons_hypoth698 PF03601.14 GAX23916.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 DNA_pol_phi PF04931.13 GAX23917.1 - 3.4e-29 101.6 17.6 1.3e-28 99.6 1.6 5.6 5 2 0 5 5 5 3 DNA polymerase phi Galactosyl_T PF01762.21 GAX23919.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase TMEM65 PF10507.9 GAX23920.1 - 1.5e-38 131.1 3.5 2.6e-38 130.3 3.5 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 ACT PF01842.25 GAX23920.1 - 0.00018 21.2 0.0 0.00052 19.7 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GAX23920.1 - 0.055 14.1 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 ACT domain Pam17 PF08566.10 GAX23920.1 - 0.18 11.7 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 HTH_35 PF13693.6 GAX23920.1 - 0.2 11.7 0.1 34 4.6 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding PspB PF06667.12 GAX23920.1 - 0.35 11.0 1.7 0.86 9.7 0.6 2.0 1 1 1 2 2 2 0 Phage shock protein B Snf7 PF03357.21 GAX23921.1 - 2.1e-23 82.8 28.1 3.5e-23 82.1 28.1 1.4 1 1 0 1 1 1 1 Snf7 YlqD PF11068.8 GAX23921.1 - 0.00036 20.9 9.8 0.00036 20.9 9.8 2.8 1 1 1 2 2 2 1 YlqD protein QRPTase_C PF01729.19 GAX23921.1 - 0.13 12.0 6.1 0.11 12.2 4.7 1.7 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF2514 PF10721.9 GAX23921.1 - 3.8 7.5 19.4 0.15 12.0 13.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2514) DUF3138 PF11336.8 GAX23921.1 - 5.4 5.5 8.6 7.6 5.0 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CP12 PF02672.15 GAX23922.1 - 4.1e-16 59.5 13.2 6.8e-10 39.6 0.9 2.8 2 2 0 2 2 2 2 CP12 domain Dak2 PF02734.17 GAX23922.1 - 0.0095 15.8 8.7 0.6 10.0 0.3 2.1 1 1 1 2 2 2 2 DAK2 domain BAR_3 PF16746.5 GAX23922.1 - 0.024 14.3 4.3 0.026 14.2 3.5 1.5 1 1 0 1 1 1 0 BAR domain of APPL family T2SSM PF04612.12 GAX23922.1 - 0.64 10.1 6.9 0.11 12.5 1.3 2.3 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Ribosomal_S26e PF01283.19 GAX23923.1 - 1.4e-48 163.8 6.4 1.5e-48 163.7 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf-MYND PF01753.18 GAX23925.1 - 0.0047 17.0 12.1 0.0047 17.0 12.1 3.1 2 2 1 3 3 3 1 MYND finger zf-C2HE PF16278.5 GAX23925.1 - 0.0062 17.0 0.4 0.029 14.8 0.0 2.3 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_10 PF10058.9 GAX23925.1 - 0.035 13.8 0.1 0.035 13.8 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Mss51 PF13824.6 GAX23925.1 - 0.06 13.5 4.0 0.17 12.0 4.0 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SNX17_FERM_C PF18116.1 GAX23925.1 - 0.063 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain Acid_PPase PF12689.7 GAX23926.1 - 1.8e-39 135.3 0.0 1.6e-38 132.2 0.0 2.1 1 1 0 1 1 1 1 Acid Phosphatase CSD PF00313.22 GAX23926.1 - 2.6e-10 40.0 0.0 5.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain ASCH PF04266.14 GAX23926.1 - 0.012 16.2 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 ASCH domain S1_2 PF13509.6 GAX23926.1 - 0.083 13.0 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 S1 domain Peptidase_M43 PF05572.13 GAX23927.1 - 2.3e-11 43.9 0.0 4.8e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX23927.1 - 0.015 15.5 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX23927.1 - 0.032 14.8 0.0 0.056 14.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 GAX23927.1 - 0.038 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 GAX23927.1 - 0.072 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAX23927.1 - 0.078 11.9 0.3 0.12 11.3 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 V-ATPase_H_C PF11698.8 GAX23928.1 - 6.1e-37 126.3 0.1 1.8e-36 124.8 0.1 1.8 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 GAX23928.1 - 6.9e-31 107.7 0.0 4.5e-30 105.0 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 GAX23928.1 - 1.1e-05 25.3 7.8 0.011 15.7 0.7 4.3 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAX23928.1 - 0.024 15.0 2.0 0.082 13.3 0.1 2.8 3 0 0 3 3 3 0 HEAT repeats DRIM PF07539.12 GAX23928.1 - 0.036 12.4 0.0 0.078 11.3 0.0 1.5 1 0 0 1 1 1 0 Down-regulated in metastasis DUF2451 PF10474.9 GAX23929.1 - 2.6e-29 102.7 0.0 1.4e-28 100.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) PAH PF02671.21 GAX23929.1 - 0.14 12.3 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Paired amphipathic helix repeat Sec7 PF01369.20 GAX23930.1 - 6.2e-10 39.1 0.0 1.6e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain TPR_12 PF13424.6 GAX23931.1 - 1.6e-10 41.1 6.1 0.00054 20.2 1.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23931.1 - 9.2e-07 28.4 0.2 0.017 15.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX23931.1 - 5.8e-06 26.0 6.1 0.13 12.4 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23931.1 - 0.0017 18.4 3.4 2.5 8.5 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX23931.1 - 0.0041 16.8 0.8 4.1 7.2 0.2 3.2 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.6 GAX23931.1 - 0.0069 16.3 4.3 15 5.9 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX23931.1 - 0.017 15.3 1.0 0.75 10.0 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAX23931.1 - 0.02 14.1 5.7 0.048 12.9 1.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX23931.1 - 0.028 15.1 11.3 0.96 10.2 0.3 4.3 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX23931.1 - 0.046 13.4 10.6 0.094 12.4 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 GAX23931.1 - 0.091 12.7 6.9 11 6.0 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX23931.1 - 0.094 12.2 2.0 10 5.6 0.1 2.7 2 0 0 2 2 2 0 SHNi-TPR SNAP PF14938.6 GAX23931.1 - 0.16 11.4 2.1 0.42 10.0 0.9 2.1 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 GAX23931.1 - 0.17 12.8 14.7 51 5.1 0.0 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat CBP_BcsR PF10945.8 GAX23931.1 - 0.88 9.1 3.7 16 5.1 3.7 2.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsR ABC_tran PF00005.27 GAX23933.1 - 3e-41 141.1 5.3 3e-20 73.1 0.1 3.9 4 1 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX23933.1 - 3.5e-22 78.2 6.0 3.5e-22 78.2 6.0 3.1 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 GAX23933.1 - 1.6e-14 54.5 7.8 0.0024 17.7 0.2 4.6 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX23933.1 - 1.9e-12 47.1 2.4 0.00025 20.5 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX23933.1 - 1.8e-07 31.5 1.1 0.0014 18.9 0.0 3.7 2 2 1 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 GAX23933.1 - 3.2e-07 30.4 0.2 0.027 14.4 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 GAX23933.1 - 3.6e-07 30.2 0.3 0.026 14.4 0.1 2.9 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.6 GAX23933.1 - 9.1e-07 29.4 1.8 0.0071 16.7 0.2 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAX23933.1 - 9.9e-07 28.4 0.1 0.017 14.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAX23933.1 - 8.2e-06 26.3 0.1 0.41 11.1 0.0 3.4 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GAX23933.1 - 2.9e-05 24.1 1.7 0.11 12.6 0.1 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAX23933.1 - 6.4e-05 23.3 0.3 0.35 11.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain Rhodanese PF00581.20 GAX23933.1 - 0.00012 22.6 0.0 0.16 12.5 0.0 3.8 3 1 1 4 4 4 1 Rhodanese-like domain AAA_24 PF13479.6 GAX23933.1 - 0.00014 21.6 2.5 5.1 6.8 0.0 4.4 4 1 0 4 4 4 1 AAA domain AAA_18 PF13238.6 GAX23933.1 - 0.0002 21.9 0.1 0.28 11.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAX23933.1 - 0.00034 21.2 0.1 0.053 14.0 0.1 4.3 5 0 0 5 5 3 2 AAA domain RNA_helicase PF00910.22 GAX23933.1 - 0.00038 20.8 0.7 2.7 8.4 0.0 3.7 3 0 0 3 3 3 1 RNA helicase Roc PF08477.13 GAX23933.1 - 0.00041 20.6 0.0 1.3 9.3 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 GAX23933.1 - 0.00055 19.8 3.0 0.21 11.2 0.1 3.3 3 1 0 3 3 3 2 AAA ATPase domain NB-ARC PF00931.22 GAX23933.1 - 0.00062 19.0 0.1 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 GAX23933.1 - 0.0015 18.4 0.5 1.3 8.9 0.3 3.1 3 0 0 3 3 3 1 NTPase AAA_14 PF13173.6 GAX23933.1 - 0.0045 17.0 0.0 4.2 7.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 GAX23933.1 - 0.0049 16.5 0.0 10 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 GAX23933.1 - 0.0075 16.4 2.1 0.95 9.6 0.0 3.3 4 1 0 4 4 2 1 AAA domain AAA_19 PF13245.6 GAX23933.1 - 0.015 15.6 0.0 0.25 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAX23933.1 - 0.026 14.4 0.0 9.6 6.0 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAX23933.1 - 0.034 14.1 0.3 5.8 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 GAX23933.1 - 0.037 14.1 2.3 2.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Dynamin family TsaE PF02367.17 GAX23933.1 - 0.041 13.9 0.1 7.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 GAX23933.1 - 0.044 12.8 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.9 GAX23933.1 - 0.055 12.6 1.7 2.7 7.1 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Arf PF00025.21 GAX23933.1 - 0.087 12.3 0.0 0.78 9.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 GAX23933.1 - 0.11 12.1 0.7 4.9 6.7 0.2 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 GAX23933.1 - 4.7 7.2 12.1 19 5.2 0.0 4.5 5 0 0 5 5 5 0 Helicase HerA, central domain GAS PF13851.6 GAX23934.1 - 6.6e-05 22.3 14.4 6.6e-05 22.3 14.4 4.4 1 1 3 4 4 3 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 GAX23934.1 - 0.00032 20.6 19.7 0.00032 20.6 19.7 4.5 1 1 3 4 4 2 2 Coiled-coil region of CCDC155 or KASH DUF2205 PF10224.9 GAX23934.1 - 0.0026 17.7 3.7 0.0026 17.7 3.7 5.1 4 2 0 4 4 3 1 Short coiled-coil protein APG6_N PF17675.1 GAX23934.1 - 0.01 16.4 19.5 0.01 16.4 19.5 6.7 3 1 3 7 7 7 0 Apg6 coiled-coil region bZIP_1 PF00170.21 GAX23934.1 - 0.028 14.5 1.8 0.028 14.5 1.8 6.0 5 1 1 6 6 5 0 bZIP transcription factor DUF948 PF06103.11 GAX23934.1 - 0.76 10.1 22.5 0.12 12.6 2.7 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Pox_A_type_inc PF04508.12 GAX23934.1 - 2 8.4 7.0 9.5 6.3 0.0 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF4140 PF13600.6 GAX23934.1 - 2.6 8.5 0.0 2.6 8.5 0.0 7.5 3 1 3 6 6 5 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.6 GAX23934.1 - 2.7 6.5 47.7 0.18 10.4 31.3 2.5 1 1 0 2 2 2 0 AAA domain Fungal_TACC PF12709.7 GAX23934.1 - 4 8.0 31.6 2.7 8.5 5.6 6.3 3 3 3 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 GAX23934.1 - 6.6 7.4 47.5 0.92 10.2 11.6 5.4 2 2 2 4 4 3 0 Initiation control protein YabA Ank_2 PF12796.7 GAX23935.1 - 3.1e-16 59.7 0.0 1.3e-10 41.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX23935.1 - 4.7e-15 54.2 4.2 6.5e-05 23.0 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAX23935.1 - 8.6e-14 51.4 4.6 9.2e-10 38.6 0.1 4.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX23935.1 - 1.2e-11 44.9 1.6 1.6e-06 28.6 0.2 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX23935.1 - 3.3e-11 43.1 8.0 0.00029 21.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 GAX23936.1 - 1.3e-09 38.1 0.6 0.004 17.4 0.0 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX23936.1 - 2e-06 28.3 0.0 0.0062 17.1 0.0 2.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX23936.1 - 2.4e-06 28.0 0.1 0.13 12.9 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX23936.1 - 2.9e-05 24.1 0.0 2.2 9.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX23936.1 - 3.5e-05 24.0 0.1 0.44 11.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat UQ_con PF00179.26 GAX23937.1 - 0.00032 20.4 0.8 0.00068 19.3 0.8 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_2 PF07719.17 GAX23940.1 - 0.002 18.1 0.5 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX23940.1 - 0.0035 17.8 0.0 0.0095 16.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23940.1 - 0.0049 17.0 0.5 0.87 10.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23940.1 - 0.035 13.9 0.2 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX23940.1 - 0.56 11.0 1.9 24 5.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX23940.1 - 1.3 10.0 3.6 9.3 7.4 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 GAX23941.1 - 4.2e-17 62.8 0.1 9.6e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 GAX23941.1 - 1.8e-10 41.2 24.9 9.7e-06 26.0 10.9 2.8 3 0 0 3 3 3 2 ShK domain-like Ribosomal_L12 PF00542.19 GAX23942.1 - 3.4e-24 85.0 7.0 4.6e-24 84.6 6.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DED PF01335.21 GAX23942.1 - 0.079 13.3 0.2 3.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Death effector domain DUF616 PF04765.13 GAX23943.1 - 8.1e-08 31.9 4.2 0.0026 17.0 0.2 3.0 1 1 1 3 3 3 2 Protein of unknown function (DUF616) Tachystatin_B PF11478.8 GAX23943.1 - 0.12 12.4 4.3 5.9 6.9 0.4 2.8 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B SRC-1 PF08832.10 GAX23944.1 - 0.031 15.3 0.1 0.073 14.1 0.0 1.7 2 0 0 2 2 2 0 Steroid receptor coactivator PseudoU_synth_2 PF00849.22 GAX23945.1 - 2.2e-24 86.4 0.1 3.2e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase JmjC PF02373.22 GAX23946.1 - 3.9e-35 120.7 0.2 7.7e-35 119.8 0.2 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 GAX23946.1 - 4.6e-13 48.9 0.7 8.9e-13 48.0 0.7 1.5 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 GAX23946.1 - 1.8e-11 44.2 14.7 4e-11 43.1 14.7 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger TPR_12 PF13424.6 GAX23949.1 - 0.016 15.5 0.1 0.07 13.4 0.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF1129 PF06570.11 GAX23949.1 - 4.3 6.8 5.7 1.5 8.3 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) An_peroxidase PF03098.15 GAX23950.1 - 5.8e-82 276.0 6.5 1.7e-72 244.7 0.1 2.4 2 1 1 3 3 3 2 Animal haem peroxidase Trypsin PF00089.26 GAX23951.1 - 1.9e-34 119.4 0.1 3.2e-34 118.7 0.1 1.4 1 0 0 1 1 1 1 Trypsin Herpes_DNAp_acc PF04929.12 GAX23951.1 - 4.9 6.0 8.4 7.5 5.4 8.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MalF_P2 PF14785.6 GAX23952.1 - 0.012 15.6 0.1 0.026 14.5 0.0 1.5 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain FHA PF00498.26 GAX23954.1 - 4.3e-18 65.4 0.0 6.9e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAX23954.1 - 9e-08 32.3 0.0 3.5e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Presenilin PF01080.17 GAX23954.1 - 9.7 4.8 5.4 13 4.4 5.4 1.1 1 0 0 1 1 1 0 Presenilin Chloroa_b-bind PF00504.21 GAX23957.1 - 1.3e-25 90.8 0.0 1.6e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Rhodanese PF00581.20 GAX23958.1 - 3.4e-07 30.8 0.0 5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 GAX23958.1 - 0.00036 20.6 0.2 0.021 14.8 0.2 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF442 PF04273.13 GAX23958.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Y_phosphatase2 PF03162.13 GAX23958.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Patatin PF01734.22 GAX23959.1 - 3.9e-20 72.9 0.0 1.1e-19 71.5 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase HAP1_N PF04849.13 GAX23959.1 - 0.0018 17.6 2.0 0.0018 17.6 2.0 1.7 1 1 1 2 2 2 1 HAP1 N-terminal conserved region LRRFIP PF09738.9 GAX23959.1 - 0.0049 16.4 2.8 0.0081 15.7 2.8 1.2 1 0 0 1 1 1 1 LRRFIP family DUF3336 PF11815.8 GAX23959.1 - 0.017 14.8 0.0 0.017 14.8 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3336) AATF-Che1 PF13339.6 GAX23959.1 - 0.065 13.9 3.7 0.78 10.4 2.5 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Plk4_PB2 PF18409.1 GAX23959.1 - 0.093 13.4 0.1 0.29 11.8 0.1 1.8 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 bZIP_2 PF07716.15 GAX23959.1 - 0.11 12.5 3.1 0.25 11.5 3.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF4191 PF13829.6 GAX23959.1 - 0.23 10.8 3.6 0.45 9.8 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) GIT_CC PF16559.5 GAX23959.1 - 1.1 9.2 6.1 2.9 7.8 6.1 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2207 PF09972.9 GAX23959.1 - 5.8 5.5 5.7 2.3 6.9 3.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TLD PF07534.16 GAX23960.1 - 5e-21 75.4 0.0 8.4e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 TLD PAS PF00989.25 GAX23961.1 - 4.2e-06 26.7 0.0 7.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold bZIP_1 PF00170.21 GAX23961.1 - 1.9e-05 24.7 6.7 1.9e-05 24.7 6.7 1.7 2 0 0 2 2 2 1 bZIP transcription factor PAS_4 PF08448.10 GAX23961.1 - 0.00017 21.8 0.0 0.00051 20.3 0.0 1.8 3 0 0 3 3 3 1 PAS fold bZIP_2 PF07716.15 GAX23961.1 - 0.00032 20.7 9.8 0.00076 19.5 9.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper PAS_9 PF13426.7 GAX23961.1 - 0.00037 20.7 0.0 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 PAS domain PGA2 PF07543.12 GAX23961.1 - 0.0041 17.1 1.8 0.0041 17.1 1.8 1.7 2 0 0 2 2 2 1 Protein trafficking PGA2 PAS_3 PF08447.12 GAX23961.1 - 0.018 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 GAX23961.1 - 0.033 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 PAS domain Aminotran_5 PF00266.19 GAX23962.1 - 3.3e-54 184.2 0.3 1.8e-53 181.9 0.3 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAX23962.1 - 1.8e-05 24.1 0.2 3e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 GAX23962.1 - 0.0042 15.8 0.0 0.0072 15.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 GAX23962.1 - 0.019 14.3 1.2 0.034 13.4 1.2 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Arena_nucleocap PF00843.17 GAX23962.1 - 0.063 12.2 0.0 0.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Arenavirus nucleocapsid N-terminal domain DUF411 PF04214.13 GAX23962.1 - 0.079 12.9 0.1 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF Rhodanese PF00581.20 GAX23963.1 - 5.6e-08 33.3 0.0 9.6e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Y_phosphatase2 PF03162.13 GAX23963.1 - 0.011 15.3 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 GAX23963.1 - 0.02 15.0 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.6 GAX23963.1 - 0.068 13.1 0.1 0.34 10.8 0.1 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family Aminotran_1_2 PF00155.21 GAX23965.1 - 2.1e-46 158.8 0.0 2.9e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAX23965.1 - 0.038 13.3 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase SelP_N PF04592.14 GAX23965.1 - 0.62 9.4 13.0 1.2 8.5 13.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PPC PF04151.15 GAX23968.1 - 0.012 16.7 0.5 0.028 15.5 0.5 1.6 1 1 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Rhomboid PF01694.22 GAX23971.1 - 3.2e-18 66.2 13.9 3.2e-18 66.2 13.9 3.0 2 2 0 2 2 2 1 Rhomboid family DUF773 PF05600.12 GAX23972.1 - 0.0031 16.3 6.7 0.0031 16.3 6.7 2.2 2 0 0 2 2 2 2 CDK5 regulatory subunit-associated protein 3 Thiamine_BP PF01910.17 GAX23972.1 - 0.067 13.1 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Thiamine-binding protein DUF423 PF04241.15 GAX23972.1 - 7.4 6.8 11.3 3.1 8.1 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF423) TPR_12 PF13424.6 GAX23973.1 - 2.1e-25 88.8 0.9 2e-10 40.8 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX23973.1 - 6.1e-18 64.1 0.2 0.00017 21.3 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23973.1 - 4.3e-15 54.8 0.6 0.0099 15.7 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX23973.1 - 1.1e-13 50.1 0.1 0.018 15.2 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23973.1 - 1.2e-13 50.0 1.0 0.011 15.9 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23973.1 - 2e-10 40.0 0.0 0.0026 17.7 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX23973.1 - 8e-06 25.5 0.4 1e-05 25.1 0.4 1.2 1 0 0 1 1 1 1 MalT-like TPR region SPO22 PF08631.10 GAX23973.1 - 4.7e-05 23.0 0.3 0.087 12.3 0.1 2.3 1 1 1 2 2 2 2 Meiosis protein SPO22/ZIP4 like RPN7 PF10602.9 GAX23973.1 - 0.00017 21.4 0.3 0.31 10.7 0.4 2.8 1 1 1 2 2 2 2 26S proteasome subunit RPN7 TPR_14 PF13428.6 GAX23973.1 - 0.00058 20.5 0.1 26 6.0 0.0 4.2 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX23973.1 - 0.002 18.4 0.4 4.8 7.8 0.0 4.9 4 2 2 6 6 6 1 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX23973.1 - 0.011 15.8 0.4 2.8 8.1 0.0 3.2 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 5 DUF627 PF04781.12 GAX23973.1 - 0.029 14.4 1.1 0.054 13.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) DUF2225 PF09986.9 GAX23973.1 - 0.046 13.4 3.2 0.089 12.5 0.4 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.6 GAX23973.1 - 0.051 13.0 1.4 0.12 11.7 0.6 1.9 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 GAX23973.1 - 0.06 14.0 1.7 27 5.7 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat PAS_9 PF13426.7 GAX23974.1 - 4.9e-16 58.9 0.0 1.1e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 GAX23974.1 - 3.2e-07 30.3 0.0 7.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold bZIP_2 PF07716.15 GAX23974.1 - 1.3e-06 28.4 7.9 2.6e-06 27.4 7.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAX23974.1 - 0.00014 21.9 7.8 0.00019 21.4 7.3 1.5 1 1 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 GAX23974.1 - 0.00069 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold CASP_C PF08172.12 GAX23974.1 - 0.055 12.8 1.5 0.074 12.4 1.5 1.2 1 0 0 1 1 1 0 CASP C terminal Chloroa_b-bind PF00504.21 GAX23975.1 - 1.2e-35 123.5 0.1 1.5e-35 123.1 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PAP_fibrillin PF04755.12 GAX23978.1 - 0.00091 19.2 0.0 1 9.3 0.0 2.4 2 1 0 2 2 2 2 PAP_fibrillin HMG_box PF00505.19 GAX23980.1 - 2e-11 44.2 4.9 1.2e-09 38.5 4.9 2.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX23980.1 - 4.7e-11 43.1 4.2 2.4e-10 40.9 4.2 2.2 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 GAX23981.1 - 9e-10 38.8 4.1 1.6e-06 28.4 1.0 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX23981.1 - 4.3e-08 33.6 6.2 7.3e-07 29.7 6.2 2.4 1 1 0 1 1 1 1 HMG-box domain Fe_hyd_lg_C PF02906.14 GAX23982.1 - 5.8e-42 144.0 0.0 1.1e-41 143.2 0.0 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF3145 PF11343.8 GAX23982.1 - 0.11 12.1 1.2 0.5 9.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) Mucin PF01456.17 GAX23982.1 - 1.1 9.2 22.2 11 6.0 19.5 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein TPR_2 PF07719.17 GAX23983.1 - 1.6e-07 30.9 7.3 0.14 12.3 0.4 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX23983.1 - 1.5e-06 27.8 5.3 0.076 12.9 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX23983.1 - 0.00018 21.5 5.5 3.8 8.0 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX23983.1 - 0.0019 17.9 1.0 0.0057 16.3 0.4 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 GAX23983.1 - 0.0019 18.4 3.7 7.4 6.9 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX23983.1 - 0.053 13.6 2.9 6.6 7.0 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat SCIMP PF15050.6 GAX23983.1 - 2.7 8.5 5.1 3.2 8.2 1.6 2.6 2 0 0 2 2 2 0 SCIMP protein FAM60A PF15396.6 GAX23983.1 - 7.3 6.5 16.7 1.7 8.6 0.7 2.6 3 0 0 3 3 3 0 Protein Family FAM60A EMC3_TMCO1 PF01956.16 GAX23984.1 - 6.5e-38 130.1 0.6 1e-37 129.5 0.6 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like T3SS_basalb_I PF17001.5 GAX23984.1 - 3 8.5 6.8 2 9.0 3.9 2.1 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI AftA_C PF12249.8 GAX23988.1 - 0.19 11.4 0.1 0.46 10.1 0.1 1.5 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal Cyclin_C_2 PF16899.5 GAX23989.1 - 2e-12 47.4 0.3 3.3e-08 33.9 0.1 2.7 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 GAX23989.1 - 8.5e-09 35.2 0.1 3.2e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain RCC1 PF00415.18 GAX23990.1 - 3e-38 130.2 17.0 4e-11 43.3 0.0 8.2 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX23990.1 - 8.1e-30 102.0 15.2 1.1e-07 31.5 0.0 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PBP1_TM PF14812.6 GAX23991.1 - 0.002 18.4 2.5 0.056 13.8 0.3 2.1 2 0 0 2 2 2 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 GAX23991.1 - 0.013 15.3 2.7 0.014 15.1 2.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mpv17_PMP22 PF04117.12 GAX23993.1 - 7.2e-15 55.0 8.4 1.8e-14 53.7 8.4 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 GAX23994.1 - 3.3e-17 62.5 1.3 6.8e-17 61.5 1.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribonuc_red_sm PF00268.21 GAX23995.1 - 1.5e-118 395.3 0.1 1.8e-118 395.0 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1978 PF09321.10 GAX23995.1 - 0.18 11.1 1.0 4.1 6.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Rsm1 PF08600.10 GAX23996.1 - 0.1 12.8 0.3 0.57 10.4 0.0 2.4 2 1 0 2 2 2 0 Rsm1-like Zn_ribbon_SprT PF17283.2 GAX23996.1 - 0.27 11.2 4.1 2.9 7.9 0.0 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain SUIM_assoc PF16619.5 GAX23996.1 - 2.1 8.4 12.8 0.49 10.5 1.9 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 UPF0047 PF01894.17 GAX23998.1 - 7.7e-36 122.7 0.0 1.6e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Sporozoite_P67 PF05642.11 GAX23998.1 - 0.45 8.6 8.5 0.58 8.2 8.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RHD3 PF05879.12 GAX23999.1 - 0.0028 15.9 7.4 0.0037 15.5 7.4 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) ASD1 PF08688.10 GAX23999.1 - 0.022 15.2 0.5 0.022 15.2 0.5 2.4 1 1 1 2 2 2 0 Apx/Shroom domain ASD1 Lamprin PF06403.11 GAX23999.1 - 0.053 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Lamprin IBR PF01485.21 GAX24001.1 - 1.7e-09 37.7 18.3 3e-06 27.4 8.5 5.0 3 2 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 GAX24001.1 - 4.1e-05 23.3 7.9 4.1e-05 23.3 7.9 5.5 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX24001.1 - 0.00019 21.7 9.4 0.00019 21.7 9.4 5.5 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX24001.1 - 0.00027 20.9 10.9 0.00027 20.9 10.9 4.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX24001.1 - 0.0042 16.9 4.3 0.0042 16.9 4.3 5.6 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF2157 PF09925.9 GAX24001.1 - 0.013 15.3 1.5 0.02 14.7 1.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Prominin PF05478.11 GAX24001.1 - 1.7 6.5 4.6 2.2 6.1 4.6 1.1 1 0 0 1 1 1 0 Prominin Ecm29 PF13001.7 GAX24002.1 - 1.4e-27 96.6 2.0 7.4e-23 81.0 0.8 4.3 3 1 0 4 4 4 3 Proteasome stabiliser HEAT PF02985.22 GAX24002.1 - 0.0031 17.6 25.8 0.76 10.2 0.4 10.5 10 0 0 10 10 10 3 HEAT repeat Lipase_GDSL_2 PF13472.6 GAX24003.1 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family LCIB_C_CA PF18599.1 GAX24004.1 - 1e-69 234.3 0.0 1.3e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SMC_Nse1 PF07574.13 GAX24005.1 - 2.1e-10 40.8 0.1 4.3e-05 23.5 0.0 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex SMC_ScpB PF04079.16 GAX24005.1 - 0.018 14.7 0.1 0.061 12.9 0.0 1.8 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB DEP PF00610.21 GAX24005.1 - 0.051 13.6 0.5 9.4 6.4 0.0 2.8 2 1 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDDEXK_1 PF12705.7 GAX24006.1 - 3.9e-25 89.2 3.6 5e-25 88.9 3.6 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Dna2 PF08696.11 GAX24006.1 - 9.2e-05 22.3 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 DUF2800 PF10926.8 GAX24006.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2800) DUF3799 PF12684.7 GAX24006.1 - 0.045 13.5 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) DUF1542 PF07564.11 GAX24006.1 - 0.14 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) zf-RanBP PF00641.18 GAX24007.1 - 0.0017 17.6 11.5 0.0037 16.6 1.9 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF3795 PF12675.7 GAX24007.1 - 0.051 14.0 1.5 0.53 10.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) zf-Sec23_Sec24 PF04810.15 GAX24007.1 - 0.37 10.9 6.2 10 6.3 0.7 3.5 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger NMO PF03060.15 GAX24008.1 - 2.4e-10 40.3 0.2 8.3e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase AMP-binding PF00501.28 GAX24010.1 - 7.6e-93 311.4 0.0 1.2e-92 310.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme RNA_pol_Rpb5_C PF01191.19 GAX24010.1 - 0.025 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain EFG_IV PF03764.18 GAX24011.1 - 4.7e-31 107.1 0.0 2.9e-30 104.5 0.0 2.2 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.24 GAX24011.1 - 1.2e-21 76.6 0.0 2.6e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 GAX24011.1 - 9e-21 74.3 0.6 1.8e-20 73.3 0.6 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAX24011.1 - 3.2e-15 56.3 0.1 4.3e-14 52.7 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAX24011.1 - 6.7e-14 51.7 0.1 1.8e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II RF3_C PF16658.5 GAX24011.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Ank_2 PF12796.7 GAX24012.1 - 3.1e-12 46.9 0.0 0.00028 21.4 0.0 4.5 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX24012.1 - 3.3e-07 30.5 0.2 0.59 10.5 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX24012.1 - 9.3e-07 29.3 1.2 5 7.8 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX24012.1 - 1.3e-05 25.2 5.9 3.1 8.7 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 GAX24012.1 - 0.00032 21.0 7.7 1.5 9.4 0.0 6.1 6 1 0 6 6 6 2 Ankyrin repeat SCAB_CC PF16712.5 GAX24012.1 - 0.77 9.6 3.3 0.27 11.0 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein EF_assoc_2 PF08356.12 GAX24013.1 - 6.5e-11 42.1 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 GAX24013.1 - 2.6e-10 40.1 0.0 6.1e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 Ras family EF-hand_1 PF00036.32 GAX24013.1 - 1.7e-07 30.3 1.3 0.013 15.0 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX24013.1 - 1.9e-07 30.4 3.0 0.0093 15.8 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAX24013.1 - 2.6e-07 31.0 2.0 9.8e-06 25.9 1.5 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX24013.1 - 1.5e-06 27.4 4.7 0.00083 18.7 0.1 3.1 3 0 0 3 3 3 2 EF hand Roc PF08477.13 GAX24013.1 - 5.2e-05 23.5 0.0 0.0072 16.5 0.0 3.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_8 PF13833.6 GAX24013.1 - 0.008 16.0 0.4 0.93 9.4 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair Arf PF00025.21 GAX24013.1 - 0.011 15.2 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX24013.1 - 0.016 14.7 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Peptidase_C14 PF00656.22 GAX24014.1 - 1.8e-42 146.0 1.5 2.2e-35 122.8 0.1 2.1 2 0 0 2 2 2 2 Caspase domain Cytomega_UL84 PF06284.11 GAX24014.1 - 0.13 10.7 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Hira PF07569.11 GAX24015.1 - 0.00029 20.6 0.1 0.82 9.3 0.0 3.1 2 1 2 4 4 4 2 TUP1-like enhancer of split PQQ_3 PF13570.6 GAX24015.1 - 0.007 16.8 2.6 6.8 7.3 2.4 4.1 4 0 0 4 4 4 1 PQQ-like domain Frtz PF11768.8 GAX24015.1 - 0.22 9.8 0.0 1.3 7.2 0.1 2.1 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 GAX24015.1 - 6.7 7.8 11.2 2.7 9.0 1.2 4.2 3 1 1 4 4 4 0 WD domain, G-beta repeat Peptidase_S8 PF00082.22 GAX24017.1 - 6.4e-39 134.0 5.5 2.3e-38 132.2 5.5 1.7 1 1 0 1 1 1 1 Subtilase family WW PF00397.26 GAX24018.1 - 0.0013 18.8 0.1 0.0013 18.8 0.1 1.6 2 0 0 2 2 2 1 WW domain DUF2813 PF11398.8 GAX24018.1 - 0.072 12.3 0.1 0.077 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Kinesin PF00225.23 GAX24019.1 - 1e-89 300.8 0.0 1.7e-89 300.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX24019.1 - 1.7e-21 76.8 0.0 2.4e-20 73.0 0.0 2.8 2 1 0 2 2 2 1 Microtubule binding Effector_1 PF04518.12 GAX24019.1 - 0.05 12.7 2.4 0.13 11.4 2.4 1.6 1 0 0 1 1 1 0 Effector from type III secretion system Golgin_A5 PF09787.9 GAX24019.1 - 0.37 10.2 35.6 0.39 10.1 0.8 3.3 2 1 2 4 4 4 0 Golgin subfamily A member 5 YlqD PF11068.8 GAX24019.1 - 2.6 8.4 24.8 0.37 11.2 5.9 4.2 4 0 0 4 4 4 0 YlqD protein DUF1664 PF07889.12 GAX24019.1 - 2.8 8.0 17.6 4.4 7.4 2.9 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 GAX24019.1 - 6.4 7.5 29.1 1.8 9.2 4.5 5.3 3 1 2 5 5 5 0 Initiation control protein YabA PRKG1_interact PF15898.5 GAX24019.1 - 6.7 7.7 37.7 0.15 13.0 4.6 4.8 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain PP2C PF00481.21 GAX24020.1 - 7.9e-36 124.0 0.6 1.9e-20 73.6 0.0 2.7 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAX24020.1 - 0.00049 19.8 0.0 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX24020.1 - 0.0082 16.1 0.0 0.038 13.9 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) tRNA_synthFbeta PF17759.1 GAX24021.1 - 5e-41 140.5 0.0 6.9e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 GAX24021.1 - 3.1e-35 120.2 0.1 1.7e-33 114.7 0.0 2.6 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 GAX24021.1 - 3.1e-21 75.8 0.0 5.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 GAX24021.1 - 1.5e-15 57.3 0.0 3.7e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase B5 domain FbpA PF05833.11 GAX24023.1 - 2.4e-13 49.7 5.8 2.4e-13 49.7 5.8 2.6 2 1 1 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_2 PF18297.1 GAX24023.1 - 5.6e-07 29.7 0.0 1.7e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_1 PF05670.13 GAX24023.1 - 8.3e-07 29.6 0.0 5.2e-06 27.1 0.0 2.3 2 1 0 2 2 2 1 NFACT protein RNA binding domain NFRKB_winged PF14465.6 GAX24023.1 - 0.11 12.7 0.4 0.28 11.4 0.4 1.7 1 0 0 1 1 1 0 NFRKB Winged Helix-like PLAC8 PF04749.17 GAX24025.1 - 0.0004 21.3 0.7 0.00053 20.9 0.7 1.3 1 0 0 1 1 1 1 PLAC8 family SUN PF03856.13 GAX24025.1 - 0.07 12.6 0.3 0.074 12.5 0.3 1.1 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) FG-GAP_2 PF14312.6 GAX24026.1 - 2.3e-54 181.4 15.1 4.1e-15 55.8 6.8 7.1 7 0 0 7 7 7 6 FG-GAP repeat HisK_sensor PF18698.1 GAX24026.1 - 0.0021 18.4 0.3 6 7.3 0.0 4.1 4 0 0 4 4 4 1 Histidine kinase sensor domain Kelch_3 PF13415.6 GAX24026.1 - 0.0054 17.0 0.1 7.1 7.1 0.0 2.8 2 0 0 2 2 2 2 Galactose oxidase, central domain Imm31 PF15591.6 GAX24026.1 - 0.2 11.5 0.9 9.5 6.2 0.1 3.4 4 0 0 4 4 4 0 Immunity protein 31 FG-GAP PF01839.23 GAX24026.1 - 9.8 6.4 26.7 1.6 8.9 0.5 5.8 7 0 0 7 7 7 0 FG-GAP repeat ABC_tran PF00005.27 GAX24027.1 - 1.4e-48 164.9 0.6 2.9e-26 92.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAX24027.1 - 1e-13 51.8 8.0 2.4e-05 24.3 0.0 4.6 4 1 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 GAX24027.1 - 3e-12 46.4 2.7 3e-12 46.4 2.7 3.2 2 1 1 3 3 2 1 ABC transporter ABC_tran_CTD PF16326.5 GAX24027.1 - 4.7e-09 36.4 10.8 1.9e-08 34.4 10.8 2.1 1 0 0 1 1 1 1 ABC transporter C-terminal domain MMR_HSR1 PF01926.23 GAX24027.1 - 6.6e-06 26.2 2.2 0.011 15.8 0.0 3.1 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 GAX24027.1 - 7e-06 26.6 0.4 0.057 14.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 GAX24027.1 - 8.1e-06 25.5 0.1 0.019 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain TsaE PF02367.17 GAX24027.1 - 1.3e-05 25.2 0.1 0.21 11.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAX24027.1 - 2e-05 24.4 3.8 0.096 12.4 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 GAX24027.1 - 3.8e-05 24.1 1.2 0.29 11.6 0.0 3.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX24027.1 - 4e-05 23.9 1.0 0.084 13.1 0.2 3.6 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GAX24027.1 - 4.3e-05 23.4 11.1 0.058 13.1 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 GAX24027.1 - 6.3e-05 22.9 1.4 0.25 11.2 0.1 3.1 3 0 0 3 3 3 2 NACHT domain RsgA_GTPase PF03193.16 GAX24027.1 - 8.9e-05 22.4 4.8 0.048 13.6 0.1 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_28 PF13521.6 GAX24027.1 - 9e-05 22.8 6.6 0.15 12.3 0.0 3.9 4 0 0 4 4 4 2 AAA domain Roc PF08477.13 GAX24027.1 - 0.00012 22.3 0.4 0.12 12.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 GAX24027.1 - 0.00012 22.2 6.6 0.01 16.0 0.1 4.1 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.19 GAX24027.1 - 0.00013 21.5 10.5 0.3 10.5 0.0 4.7 4 1 0 5 5 5 1 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 GAX24027.1 - 0.00017 21.9 0.1 0.95 9.9 0.1 2.6 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 GAX24027.1 - 0.00046 20.2 0.9 0.14 12.1 0.1 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GAX24027.1 - 0.00053 19.6 6.9 0.23 11.0 0.0 4.4 5 0 0 5 5 5 1 AAA domain NTPase_1 PF03266.15 GAX24027.1 - 0.00065 19.6 2.2 4.2 7.3 0.1 3.8 3 1 0 3 3 3 0 NTPase AAA_13 PF13166.6 GAX24027.1 - 0.0013 17.5 9.0 0.46 9.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain dNK PF01712.19 GAX24027.1 - 0.0016 18.3 1.1 0.82 9.5 0.1 2.7 2 0 0 2 2 2 1 Deoxynucleoside kinase ATP-synt_ab PF00006.25 GAX24027.1 - 0.003 17.2 0.1 2.6 7.6 0.0 2.5 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 GAX24027.1 - 0.0036 17.0 1.1 0.94 9.1 0.2 2.7 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAX24027.1 - 0.011 16.2 3.5 0.32 11.4 0.5 2.9 2 2 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 GAX24027.1 - 0.012 15.1 0.2 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 GAX24027.1 - 0.014 15.6 0.1 9.6 6.5 0.0 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 GAX24027.1 - 0.019 14.2 0.1 1.7 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) kleA_kleC PF17383.2 GAX24027.1 - 0.021 15.2 3.7 0.034 14.5 1.7 2.4 2 0 0 2 2 1 0 Uncharacterized KorC regulated protein A cobW PF02492.19 GAX24027.1 - 0.026 14.1 1.2 2.9 7.4 0.2 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SOAR PF16533.5 GAX24027.1 - 0.027 14.4 8.8 0.1 12.6 8.8 1.9 1 0 0 1 1 1 0 STIM1 Orai1-activating region AAA_30 PF13604.6 GAX24027.1 - 0.028 14.1 0.6 1.1 9.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 GAX24027.1 - 0.035 13.6 0.1 10 5.6 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.6 GAX24027.1 - 0.054 14.0 0.3 0.054 14.0 0.3 3.7 2 2 0 2 2 1 0 AAA domain RuvB_N PF05496.12 GAX24027.1 - 0.082 12.7 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 GAX24027.1 - 0.085 12.6 1.0 5.9 6.6 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 GAX24027.1 - 0.087 12.9 0.1 14 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain TolA_bind_tri PF16331.5 GAX24027.1 - 0.11 12.6 5.4 0.39 10.8 5.4 2.0 1 0 0 1 1 1 0 TolA binding protein trimerisation Bacillus_HBL PF05791.11 GAX24027.1 - 0.15 11.8 6.8 0.39 10.5 4.0 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1510 PF07423.11 GAX24027.1 - 0.2 11.8 1.3 8.4 6.6 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) Dynamin_N PF00350.23 GAX24027.1 - 0.22 11.5 5.7 4.7 7.2 0.0 3.2 3 1 0 3 3 3 0 Dynamin family Zeta_toxin PF06414.12 GAX24027.1 - 0.51 9.6 9.7 0.86 8.8 0.0 3.7 4 0 0 4 4 4 0 Zeta toxin DUF1043 PF06295.12 GAX24027.1 - 1.1 9.3 6.7 0.26 11.3 2.0 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.15 GAX24027.1 - 1.1 8.7 5.8 0.32 10.5 2.2 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit FapA PF03961.13 GAX24027.1 - 1.4 7.4 6.7 2 6.9 6.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 GAX24027.1 - 1.7 8.7 9.0 0.71 9.9 6.2 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 GAX24027.1 - 2.2 8.1 9.5 1.4 8.8 4.5 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 GAX24027.1 - 2.2 7.5 10.7 1.8 7.9 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 GAX24027.1 - 3.9 6.5 14.0 0.21 10.6 8.1 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 GAX24027.1 - 4.1 7.5 14.2 0.49 10.4 8.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sina PF03145.16 GAX24029.1 - 1.3e-05 25.3 2.5 2.4e-05 24.4 2.5 1.4 1 0 0 1 1 1 1 Seven in absentia protein family zf-RING_2 PF13639.6 GAX24029.1 - 1.4e-05 25.3 10.2 4.5e-05 23.7 10.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAX24029.1 - 1.7e-05 24.6 8.6 3.5e-05 23.6 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX24029.1 - 4.1e-05 23.3 10.1 4.1e-05 23.3 10.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 GAX24029.1 - 0.00016 22.3 7.4 0.00027 21.6 6.6 1.8 1 1 0 1 1 1 1 TRAF-type zinc finger Siva PF05458.12 GAX24029.1 - 0.00058 19.6 3.5 0.0012 18.5 3.5 1.5 1 0 0 1 1 1 1 Cd27 binding protein (Siva) zf-TRAF_2 PF15965.5 GAX24029.1 - 0.0014 19.0 6.9 0.0014 19.0 6.9 2.0 1 1 1 2 2 2 1 TRAF-like zinc-finger zf-C3HC4 PF00097.25 GAX24029.1 - 0.016 15.1 10.3 0.038 13.8 10.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX24029.1 - 0.24 11.5 8.7 0.049 13.7 3.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAX24029.1 - 0.25 11.3 11.0 0.57 10.2 11.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GAX24029.1 - 0.81 9.6 7.6 2.3 8.2 7.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CCHC PF00098.23 GAX24030.1 - 1.8e-07 30.9 5.0 3.3e-07 30.1 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GAX24030.1 - 0.03 14.3 1.4 0.058 13.4 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GAX24030.1 - 0.045 13.5 1.2 0.045 13.5 1.2 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GAX24030.1 - 0.29 10.9 1.0 0.96 9.2 1.0 1.9 1 0 0 1 1 1 0 Zinc knuckle API5 PF05918.11 GAX24030.1 - 0.44 9.3 1.7 0.7 8.6 1.7 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4746 PF15928.5 GAX24031.1 - 0.032 13.7 0.4 0.05 13.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4611 PF15387.6 GAX24031.1 - 0.12 12.6 13.7 1.6 9.0 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GAX24031.1 - 0.16 11.2 15.0 0.11 11.8 4.6 2.1 2 0 0 2 2 2 0 NOA36 protein E7 PF00527.18 GAX24031.1 - 0.26 11.5 8.9 2.1 8.6 1.3 2.8 3 0 0 3 3 3 0 E7 protein, Early protein CENP-B_dimeris PF09026.10 GAX24031.1 - 0.43 11.0 20.3 0.58 10.6 8.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BUD22 PF09073.10 GAX24031.1 - 0.45 9.8 8.4 0.61 9.4 8.4 1.2 1 0 0 1 1 1 0 BUD22 SHP PF03579.13 GAX24031.1 - 0.54 10.3 2.6 0.89 9.6 2.6 1.3 1 0 0 1 1 1 0 Small hydrophobic protein ELM2 PF01448.24 GAX24031.1 - 2.7 8.8 9.9 3.9 8.3 0.8 2.4 2 0 0 2 2 2 0 ELM2 domain Sigma70_ner PF04546.13 GAX24031.1 - 2.9 7.7 10.3 4.2 7.2 1.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region S-antigen PF05756.11 GAX24031.1 - 3.4 8.1 7.5 6.4 7.2 0.8 2.4 2 0 0 2 2 2 0 S-antigen protein Spt5_N PF11942.8 GAX24031.1 - 4.4 8.3 19.5 9.8 7.2 6.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3246 PF11596.8 GAX24031.1 - 4.9 6.5 10.1 9 5.6 9.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) GEN1_C PF18380.1 GAX24031.1 - 6.3 7.7 6.9 23 5.9 0.4 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain RXT2_N PF08595.11 GAX24031.1 - 6.4 6.8 8.4 13 5.8 2.2 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal TFIIE-A_C PF11521.8 GAX24031.1 - 7.1 7.0 12.7 6 7.2 1.1 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha PBP1_TM PF14812.6 GAX24031.1 - 8 6.9 15.6 7 7.1 2.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_trans_1_4 PF13692.6 GAX24032.1 - 7.1e-05 23.3 0.0 0.017 15.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX24032.1 - 0.00031 20.3 0.0 0.091 12.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAX24032.1 - 0.038 14.4 0.2 0.16 12.4 0.0 2.2 1 1 1 2 2 2 0 Glycosyl transferases group 1 LPD39 PF18858.1 GAX24032.1 - 0.093 12.8 0.1 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 EF-1_beta_acid PF10587.9 GAX24033.1 - 0.18 12.3 0.1 0.18 12.3 0.1 3.2 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region ShK PF01549.24 GAX24034.1 - 0.045 14.3 26.1 0.11 13.1 4.9 4.3 4 0 0 4 4 4 0 ShK domain-like Pilin_N PF07790.11 GAX24036.1 - 0.097 13.6 0.0 0.24 12.3 0.0 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal LRR_8 PF13855.6 GAX24037.1 - 0.052 13.3 4.3 0.087 12.6 1.9 2.2 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 GAX24037.1 - 0.063 13.7 0.8 0.19 12.2 0.8 1.9 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAX24037.1 - 0.54 10.6 6.0 0.054 13.8 1.1 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Glycos_transf_1 PF00534.20 GAX24038.1 - 0.0014 18.2 0.0 0.21 11.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX24038.1 - 0.0068 16.8 0.0 0.43 11.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 5_nucleotid_C PF02872.18 GAX24039.1 - 1.7e-29 103.0 0.0 2.9e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 GAX24039.1 - 5.1e-09 36.9 0.0 8.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Diphthamide_syn PF01866.17 GAX24040.1 - 4.4e-107 358.0 0.0 5.7e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Dicty_REP PF05086.12 GAX24040.1 - 0.78 7.7 4.4 0.97 7.3 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Amidohydro_1 PF01979.20 GAX24042.1 - 5.1e-60 203.6 0.0 7e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAX24042.1 - 7.6e-08 32.2 1.5 4.7e-06 26.3 0.0 2.8 2 1 1 3 3 3 1 Amidohydrolase family A_deaminase PF00962.22 GAX24042.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase HSF_DNA-bind PF00447.17 GAX24043.1 - 1.1e-14 54.8 0.1 2.3e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding PD40 PF07676.12 GAX24043.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Pro_isomerase PF00160.21 GAX24044.1 - 0.00062 20.1 0.0 0.00085 19.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4834 PF16118.5 GAX24045.1 - 4.4 8.3 6.4 6.1 7.9 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 GAX24045.1 - 5.1 5.8 6.1 4.8 5.8 6.1 1.1 1 0 0 1 1 1 0 Presenilin SRP68 PF16969.5 GAX24046.1 - 0.0077 15.3 3.7 0.11 11.5 0.3 2.1 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 TPR_7 PF13176.6 GAX24046.1 - 0.014 15.4 0.2 0.042 13.9 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX24046.1 - 0.065 13.5 0.1 0.065 13.5 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Menin PF05053.13 GAX24046.1 - 0.095 11.1 8.6 0.12 10.7 8.6 1.1 1 0 0 1 1 1 0 Menin PAP_RNA-bind PF04926.15 GAX24046.1 - 0.1 12.2 5.3 0.16 11.6 1.8 2.1 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain Secretin_N_2 PF07655.13 GAX24046.1 - 2.1 9.0 19.9 4.9 7.8 19.9 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Spore_YhcN_YlaJ PF09580.10 GAX24046.1 - 4.6 7.3 19.5 0.47 10.5 15.3 1.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) HLH PF00010.26 GAX24047.1 - 5.1e-05 23.1 0.3 0.00016 21.6 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ERM PF00769.19 GAX24047.1 - 0.099 12.4 0.1 0.099 12.4 0.1 3.0 3 1 0 3 3 3 0 Ezrin/radixin/moesin family Mpp10 PF04006.12 GAX24047.1 - 1.9 6.8 20.6 0.047 12.1 14.2 1.5 2 0 0 2 2 2 0 Mpp10 protein CLZ PF16526.5 GAX24047.1 - 2.1 8.7 8.6 0.48 10.8 1.6 2.5 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels WXG100 PF06013.12 GAX24047.1 - 3.4 8.0 8.1 0.88 9.9 3.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Macoilin PF09726.9 GAX24047.1 - 5.4 5.4 29.9 0.93 8.0 23.1 2.2 2 0 0 2 2 2 0 Macoilin family Peptidase_M6 PF05547.11 GAX24048.1 - 8.6e-05 21.1 6.9 0.00022 19.7 6.5 1.9 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 ZapB PF06005.12 GAX24049.1 - 0.43 11.1 7.0 1.8 9.1 5.8 2.4 1 1 1 2 2 2 0 Cell division protein ZapB PP2C PF00481.21 GAX24050.1 - 8.1e-59 199.3 0.0 1.2e-56 192.2 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX24050.1 - 0.0014 18.3 0.0 0.0037 16.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C adh_short PF00106.25 GAX24051.1 - 6e-23 81.3 0.0 1.1e-19 70.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX24051.1 - 5.7e-12 45.7 0.0 1.2e-11 44.6 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAX24051.1 - 7.2e-07 28.9 0.0 2.4e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAX24051.1 - 4.7e-05 23.4 0.0 6.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 GAX24051.1 - 0.085 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glucosamine_iso PF01182.20 GAX24054.1 - 2e-53 181.6 0.0 2.7e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CRAL_TRIO PF00650.20 GAX24055.1 - 4.8e-37 127.1 0.0 7.8e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX24055.1 - 0.0035 17.5 0.0 0.0081 16.3 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RHS_repeat PF05593.14 GAX24055.1 - 0.0061 17.0 0.2 0.022 15.3 0.2 1.9 1 0 0 1 1 1 1 RHS Repeat CRAL_TRIO_N PF03765.15 GAX24055.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain TPR_12 PF13424.6 GAX24056.1 - 1.1e-15 57.7 30.7 3.1e-05 24.2 6.8 6.0 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAX24056.1 - 1.4e-08 34.2 15.8 0.00053 20.0 2.6 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX24056.1 - 6.8e-08 32.0 28.2 0.0045 17.0 2.9 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24056.1 - 1.4e-07 31.0 22.3 0.0056 16.4 3.2 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat DUF3856 PF12968.7 GAX24056.1 - 1.1e-05 25.6 1.5 0.00019 21.5 0.2 3.1 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 GAX24056.1 - 5.8e-05 23.5 24.2 0.19 12.3 9.4 5.6 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX24056.1 - 0.00051 19.5 31.7 0.0029 17.0 0.2 4.1 1 1 2 4 4 4 2 MalT-like TPR region SNAP PF14938.6 GAX24056.1 - 0.00076 19.0 17.8 0.33 10.3 6.8 3.3 3 0 0 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 GAX24056.1 - 0.0023 17.6 20.0 0.43 10.3 1.4 6.4 6 1 1 7 7 7 3 TPR repeat TPR_10 PF13374.6 GAX24056.1 - 0.0032 17.3 19.3 9.3 6.3 0.4 7.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX24056.1 - 0.0053 17.4 16.9 0.11 13.1 0.3 5.3 5 1 0 6 6 5 2 Tetratricopeptide repeat DUF3560 PF12083.8 GAX24056.1 - 0.1 12.7 0.1 0.47 10.6 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) TPR_17 PF13431.6 GAX24056.1 - 0.15 12.5 16.1 0.86 10.1 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX24056.1 - 2.8 8.8 9.8 12 6.9 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat MCC-bdg_PDZ PF10506.9 GAX24056.1 - 2.8 8.0 7.8 0.56 10.3 1.8 2.9 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TPR_14 PF13428.6 GAX24056.1 - 4.5 8.4 26.4 62 4.8 0.9 7.8 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX24056.1 - 6.2 7.1 18.0 5.2 7.3 1.7 6.2 7 2 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX24056.1 - 7.5 6.8 16.0 8.7 6.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 GAX24057.1 - 1.8e-12 47.2 0.0 3.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phos_pyr_kin PF08543.12 GAX24059.1 - 3e-16 59.6 0.0 3.8e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 GAX24059.1 - 7.8e-07 28.7 0.0 1.7e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase IL10 PF00726.17 GAX24059.1 - 0.073 12.6 0.0 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 Interleukin 10 Branch PF02485.21 GAX24060.1 - 6.2e-05 22.6 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DnaJ PF00226.31 GAX24061.1 - 0.035 14.3 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain Rick_17kDa_Anti PF05433.15 GAX24061.1 - 0.31 10.9 2.4 0.53 10.2 2.4 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain ZapB PF06005.12 GAX24062.1 - 0.0069 16.8 8.6 0.021 15.3 8.6 1.8 1 1 0 1 1 1 1 Cell division protein ZapB XRCC4 PF06632.12 GAX24062.1 - 0.012 14.5 2.6 0.02 13.8 2.6 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SHE3 PF17078.5 GAX24062.1 - 0.014 15.2 5.8 0.46 10.2 4.1 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 CENP-H PF05837.12 GAX24062.1 - 0.02 15.3 4.3 0.02 15.3 4.3 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Cep57_CLD_2 PF14197.6 GAX24062.1 - 0.028 14.5 1.1 0.028 14.5 1.1 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 YabA PF06156.13 GAX24062.1 - 0.036 14.7 3.3 0.098 13.3 3.3 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Drf_GBD PF06371.13 GAX24062.1 - 0.054 13.1 2.8 0.73 9.4 2.8 2.1 1 1 0 1 1 1 0 Diaphanous GTPase-binding Domain TSC22 PF01166.18 GAX24062.1 - 0.083 13.2 4.8 0.24 11.7 2.1 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family Sirohm_synth_M PF14824.6 GAX24062.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central JIP_LZII PF16471.5 GAX24062.1 - 0.24 11.6 5.5 0.32 11.2 3.1 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 GAX24062.1 - 0.61 10.7 6.5 1 10.0 5.5 1.9 2 0 0 2 2 1 0 SlyX DUF2205 PF10224.9 GAX24062.1 - 0.93 9.5 6.5 2.3 8.3 5.6 2.1 1 1 1 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 GAX24062.1 - 0.93 9.3 4.9 2.8 7.8 4.9 1.8 1 1 0 1 1 1 0 Septum formation initiator FlxA PF14282.6 GAX24062.1 - 0.99 9.4 6.5 0.2 11.7 2.7 1.7 2 0 0 2 2 2 0 FlxA-like protein Syntaxin-6_N PF09177.11 GAX24062.1 - 1.5 9.5 6.4 0.34 11.5 2.7 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 GAX24062.1 - 8.9 6.9 12.1 40 4.7 12.1 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Aldose_epim PF01263.20 GAX24065.1 - 0.0012 18.3 0.0 0.0032 16.8 0.0 1.7 2 0 0 2 2 2 1 Aldose 1-epimerase NtCtMGAM_N PF16863.5 GAX24065.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Caenor_Her-1 PF09232.10 GAX24066.1 - 0.061 13.5 0.5 0.11 12.6 0.2 1.6 1 1 0 1 1 1 0 Caenorhabditis elegans Her-1 ClpS PF02617.17 GAX24067.1 - 0.096 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS MORN PF02493.20 GAX24068.1 - 0.00014 21.6 2.6 0.00014 21.6 2.6 2.9 3 0 0 3 3 3 1 MORN repeat Dpy-30 PF05186.13 GAX24069.1 - 3.5e-18 65.0 0.5 4.8e-18 64.6 0.5 1.2 1 0 0 1 1 1 1 Dpy-30 motif IreB PF06135.12 GAX24069.1 - 0.016 15.4 0.6 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 IreB regulatory phosphoprotein RdDM_RDM1 PF09187.10 GAX24069.1 - 0.025 14.6 0.2 0.039 14.0 0.1 1.3 1 1 0 1 1 1 0 RNA-directed DNA methylation 1 DUF5586 PF17824.1 GAX24069.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5586) Myosin_head PF00063.21 GAX24070.1 - 5.6e-184 613.1 1.8 5.6e-184 613.1 1.8 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_16 PF13191.6 GAX24070.1 - 0.0035 17.7 0.0 0.0035 17.7 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain IQ PF00612.27 GAX24070.1 - 0.025 14.3 0.5 0.084 12.7 0.5 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.6 GAX24070.1 - 0.037 14.3 0.0 0.3 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Piwi PF02171.17 GAX24071.1 - 7e-31 107.6 0.0 1.2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 GAX24071.1 - 0.00017 21.4 0.9 0.00038 20.3 0.9 1.5 1 0 0 1 1 1 1 PAZ domain DOG1 PF14144.6 GAX24071.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Seed dormancy control Myosin_head PF00063.21 GAX24072.1 - 4.1e-181 603.6 1.8 4.1e-181 603.6 1.8 1.9 2 1 1 3 3 3 1 Myosin head (motor domain) AAA_22 PF13401.6 GAX24072.1 - 0.095 13.0 0.0 0.81 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX24072.1 - 0.13 12.6 1.7 0.73 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 GAX24072.1 - 0.13 12.6 2.7 0.6 10.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain CRF PF00473.17 GAX24072.1 - 0.45 10.6 1.6 1.5 8.9 1.6 2.0 1 0 0 1 1 1 0 Corticotropin-releasing factor family Myosin_head PF00063.21 GAX24073.1 - 8.4e-177 589.4 0.1 8.4e-177 589.4 0.1 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 GAX24073.1 - 0.00012 21.8 0.2 0.00054 19.7 0.2 2.1 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 GAX24073.1 - 0.035 13.9 0.8 0.087 12.7 0.8 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.6 GAX24073.1 - 0.038 14.3 0.3 0.99 9.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain SPOR PF05036.13 GAX24073.1 - 0.046 14.1 1.3 1 9.8 0.0 3.2 2 0 0 2 2 2 0 Sporulation related domain AAA_16 PF13191.6 GAX24073.1 - 0.07 13.5 0.0 0.07 13.5 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain peroxidase PF00141.23 GAX24074.1 - 1.1e-44 152.9 0.0 1.7e-44 152.2 0.0 1.3 1 1 0 1 1 1 1 Peroxidase Glyco_hydro_47 PF01532.20 GAX24075.1 - 2.9e-137 458.3 0.0 3.6e-137 458.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HATPase_c_3 PF13589.6 GAX24076.1 - 2.2e-05 24.3 0.0 4.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cauli_AT PF03233.13 GAX24076.1 - 0.04 13.9 0.7 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 Aphid transmission protein Phage_GP20 PF06810.11 GAX24076.1 - 0.057 13.2 2.2 0.11 12.3 2.2 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 GAX24076.1 - 0.062 13.5 0.9 0.14 12.3 0.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4715 PF15835.5 GAX24076.1 - 0.2 11.8 0.9 0.4 10.8 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) ADIP PF11559.8 GAX24076.1 - 0.21 11.7 2.9 0.42 10.7 2.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 GAX24076.1 - 0.26 11.4 3.3 0.67 10.1 3.1 1.8 1 1 0 1 1 1 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 GAX24076.1 - 0.41 10.9 5.5 1 9.7 5.5 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Lzipper-MIP1 PF14389.6 GAX24076.1 - 0.47 10.8 4.3 3.9 7.8 1.4 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 BST2 PF16716.5 GAX24076.1 - 1.4 9.6 4.6 1.6 9.3 2.8 2.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 GAX24076.1 - 1.4 8.7 6.6 2.7 7.8 1.7 2.3 1 1 1 2 2 2 0 Septum formation initiator GPAT_N PF14829.6 GAX24077.1 - 0.15 12.0 0.0 19 5.3 0.0 2.7 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal ABC_tran PF00005.27 GAX24078.1 - 4.2e-43 147.2 2.6 4.7e-20 72.5 0.0 4.1 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX24078.1 - 2.1e-21 75.7 7.5 2.1e-21 75.7 7.5 4.1 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 GAX24078.1 - 1.6e-17 64.3 1.3 9e-05 22.4 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX24078.1 - 7.9e-09 35.3 1.1 0.053 13.0 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX24078.1 - 2.6e-07 30.3 0.0 0.033 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAX24078.1 - 5.5e-07 30.1 0.2 0.0093 16.4 0.0 3.4 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 GAX24078.1 - 6e-06 26.3 0.5 0.029 14.3 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 GAX24078.1 - 1.1e-05 25.9 0.8 0.12 12.8 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 GAX24078.1 - 1.7e-05 25.1 0.0 0.073 13.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX24078.1 - 3.4e-05 24.4 3.8 0.11 13.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.6 GAX24078.1 - 9e-05 23.1 0.2 0.014 15.9 0.0 4.9 5 1 1 6 6 4 2 AAA domain MMR_HSR1 PF01926.23 GAX24078.1 - 0.00015 21.8 0.1 0.85 9.7 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_24 PF13479.6 GAX24078.1 - 0.00034 20.4 0.3 0.39 10.4 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAX24078.1 - 0.00046 20.5 3.6 0.62 10.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 GAX24078.1 - 0.00072 19.7 0.0 0.41 10.8 0.1 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX24078.1 - 0.0011 18.9 1.1 1.3 9.0 0.2 2.6 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 GAX24078.1 - 0.0015 18.6 0.1 2.6 8.1 0.0 3.8 4 1 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 GAX24078.1 - 0.0015 18.8 0.8 0.94 9.9 0.0 3.1 3 1 0 3 3 2 1 RNA helicase AAA_5 PF07728.14 GAX24078.1 - 0.0017 18.4 0.1 1.4 8.9 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 GAX24078.1 - 0.0017 18.1 0.9 0.75 9.5 0.0 3.0 4 0 0 4 4 2 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 GAX24078.1 - 0.0034 17.2 0.0 0.94 9.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 GAX24078.1 - 0.004 17.2 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 GAX24078.1 - 0.0059 16.2 2.4 1.1 8.8 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_15 PF13175.6 GAX24078.1 - 0.008 15.9 24.1 0.054 13.2 0.0 5.3 5 1 0 5 5 5 2 AAA ATPase domain NB-ARC PF00931.22 GAX24078.1 - 0.008 15.4 0.0 3.7 6.7 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain Seryl_tRNA_N PF02403.22 GAX24078.1 - 0.01 16.1 0.9 0.01 16.1 0.9 3.2 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF2205 PF10224.9 GAX24078.1 - 0.02 14.9 0.1 0.16 12.0 0.1 2.6 1 0 0 1 1 1 0 Short coiled-coil protein AAA_7 PF12775.7 GAX24078.1 - 0.024 14.1 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region KTI12 PF08433.10 GAX24078.1 - 0.044 13.2 1.2 0.14 11.6 1.2 1.8 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 GAX24078.1 - 0.046 13.6 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 GAX24078.1 - 0.059 13.1 4.3 2.9 7.6 0.4 3.2 3 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 GAX24078.1 - 0.14 12.1 5.3 2.8 7.8 0.0 3.4 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea MukB PF04310.12 GAX24078.1 - 0.51 10.1 2.6 6.7 6.5 0.0 3.2 3 1 0 3 3 3 0 MukB N-terminal AAA_27 PF13514.6 GAX24078.1 - 0.79 9.3 5.7 11 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 GAX24078.1 - 1.9 8.6 0.0 1.9 8.6 0.0 3.9 5 0 0 5 5 4 0 Helicase HerA, central domain DUF543 PF04418.12 GAX24079.1 - 2.2e-08 34.0 0.1 2.2e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Rick_17kDa_Anti PF05433.15 GAX24079.1 - 0.53 10.2 20.5 0.95 9.4 20.5 1.4 1 1 0 1 1 1 0 Glycine zipper 2TM domain Sybindin PF04099.12 GAX24080.1 - 1.6e-15 57.3 0.0 4.1e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Sybindin-like family MFS_1 PF07690.16 GAX24081.1 - 2.2e-18 66.3 35.1 2.2e-18 66.3 35.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TerY_C PF15616.6 GAX24082.1 - 0.037 14.1 1.3 0.064 13.4 1.3 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain Rhomboid PF01694.22 GAX24083.1 - 7.1e-31 107.2 7.2 7.1e-31 107.2 7.2 1.9 3 0 0 3 3 3 1 Rhomboid family PMI_typeI PF01238.21 GAX24084.1 - 1.4e-93 314.0 0.0 1.1e-92 311.2 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I DegT_DnrJ_EryC1 PF01041.17 GAX24084.1 - 0.095 12.0 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cupin_2 PF07883.11 GAX24084.1 - 0.23 11.2 0.5 15 5.4 0.0 2.7 3 0 0 3 3 3 0 Cupin domain Radical_SAM_C PF16199.5 GAX24085.1 - 3.2e-31 107.2 0.1 6.2e-31 106.3 0.1 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 GAX24085.1 - 1.8e-18 67.4 0.0 7.2e-18 65.5 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 GAX24085.1 - 1e-08 35.4 0.1 3.3e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX24085.1 - 5.2e-05 23.2 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX24085.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Alpha-mann_mid PF09261.11 GAX24085.1 - 0.17 12.1 0.0 4.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Alpha mannosidase middle domain HMG_box PF00505.19 GAX24086.1 - 4.6e-09 36.6 2.8 1.5e-05 25.3 0.5 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX24086.1 - 3.2e-08 34.1 3.5 1.7e-05 25.3 0.8 2.6 2 0 0 2 2 2 2 HMG-box domain Pkinase PF00069.25 GAX24087.1 - 1.9e-49 168.4 0.0 1.1e-33 116.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24087.1 - 4.5e-24 85.1 0.0 4.8e-20 71.9 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase B56 PF01603.20 GAX24087.1 - 6.9e-20 71.4 7.2 1.1e-19 70.7 7.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Kdo PF06293.14 GAX24087.1 - 0.0064 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX24087.1 - 0.037 13.3 0.0 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 Kinase-like IDH PF03971.14 GAX24088.1 - 0 1168.7 0.5 0 1168.5 0.5 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase DnaJ PF00226.31 GAX24089.1 - 9.9e-09 35.2 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Sulfotransfer_1 PF00685.27 GAX24091.1 - 0.0058 16.1 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain PilS PF08805.11 GAX24092.1 - 0.0085 15.9 0.1 0.0094 15.8 0.1 1.1 1 0 0 1 1 1 1 PilS N terminal Myb_DNA-binding PF00249.31 GAX24093.1 - 1e-11 44.8 0.1 3e-11 43.3 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX24093.1 - 5.1e-06 26.6 0.1 3.5e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 GAX24093.1 - 0.04 13.9 0.1 0.099 12.7 0.1 1.7 1 0 0 1 1 1 0 SLIDE CmcI PF04989.12 GAX24093.1 - 0.14 11.8 0.2 0.29 10.8 0.2 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase Myb_DNA-binding PF00249.31 GAX24094.1 - 0.00084 19.5 1.7 0.0011 19.1 0.3 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain HLH PF00010.26 GAX24094.1 - 0.018 15.0 0.4 0.054 13.5 0.4 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain LysM PF01476.20 GAX24095.1 - 0.00014 21.9 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 LysM domain PA PF02225.22 GAX24096.1 - 4.9e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF1610 PF07754.11 GAX24097.1 - 0.17 11.9 3.5 0.31 11.0 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Prok-RING_1 PF14446.6 GAX24097.1 - 1.7 8.7 9.0 3.8 7.5 6.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF1995 PF09353.10 GAX24099.1 - 2.8e-28 99.3 0.0 4.1e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF2470 PF10615.9 GAX24099.1 - 0.027 15.1 0.0 0.056 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) HMG_box PF00505.19 GAX24101.1 - 3.9e-10 40.0 4.8 4.4e-08 33.4 1.8 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX24101.1 - 5.2e-07 30.2 2.1 0.00022 21.7 1.4 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 GAX24101.1 - 0.014 15.3 0.5 0.014 15.3 0.5 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 LsmAD PF06741.13 GAX24102.1 - 3e-23 82.1 1.8 3e-23 82.1 1.8 2.6 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 GAX24102.1 - 1e-13 51.2 0.0 2.9e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 GAX24102.1 - 7.9e-06 25.2 2.7 0.015 14.9 0.2 2.9 1 1 1 2 2 2 2 Ataxin-2 C-terminal region Gemin7 PF11095.8 GAX24102.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) TPR_2 PF07719.17 GAX24103.1 - 3.5e-10 39.2 8.3 0.0025 17.8 0.6 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24103.1 - 1.2e-06 28.1 10.0 0.011 15.6 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX24103.1 - 8.7e-05 22.4 4.3 0.49 10.7 0.6 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX24103.1 - 0.0012 18.5 1.3 0.26 11.0 0.2 2.9 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 GAX24103.1 - 0.002 18.4 4.9 1.4 9.2 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat L_lactis_ph-MCP PF06673.11 GAX24103.1 - 0.055 12.5 0.8 0.1 11.6 0.8 1.4 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF2262 PF10020.9 GAX24103.1 - 0.06 13.7 1.3 0.13 12.6 1.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Sel1 PF08238.12 GAX24103.1 - 0.17 12.6 2.1 1.7 9.4 0.1 2.9 3 0 0 3 3 3 0 Sel1 repeat MIT PF04212.18 GAX24103.1 - 1.7 8.7 7.5 0.6 10.2 0.9 2.9 2 2 0 2 2 2 0 MIT (microtubule interacting and transport) domain Tyrosinase PF00264.20 GAX24104.1 - 0.1 12.9 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase HA PF03457.14 GAX24105.1 - 1.3e-25 89.5 0.5 2.6e-09 37.3 0.0 5.8 6 0 0 6 6 6 5 Helicase associated domain Transglut_core2 PF13369.6 GAX24106.1 - 8.3e-36 122.9 0.0 1.6e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Acetyltransf_10 PF13673.7 GAX24107.1 - 2.8e-08 33.8 0.1 4e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX24107.1 - 1.8e-06 28.2 0.0 2.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_39 PF01229.17 GAX24107.1 - 0.0022 16.7 0.1 0.0032 16.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Acetyltransf_7 PF13508.7 GAX24107.1 - 0.0028 18.0 0.0 0.0053 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lyase_1 PF00206.20 GAX24108.1 - 5.7e-24 85.1 0.0 8.9e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GAX24108.1 - 1.4e-17 63.8 0.0 3.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Lyase_1 PF00206.20 GAX24109.1 - 2.3e-55 188.2 0.2 3.4e-55 187.6 0.0 1.3 2 0 0 2 2 2 1 Lyase Methyltransf_25 PF13649.6 GAX24110.1 - 5.2e-14 52.7 0.0 3.2e-12 47.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX24110.1 - 1.1e-11 45.2 0.0 2e-10 41.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX24110.1 - 3.6e-10 39.9 0.0 8e-10 38.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX24110.1 - 6.7e-10 38.7 0.0 3.6e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAX24110.1 - 5.2e-07 29.6 0.0 9.8e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAX24110.1 - 1.5e-05 25.6 0.0 0.42 11.4 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Rsm22 PF09243.10 GAX24110.1 - 0.00034 20.0 0.0 0.53 9.5 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 GAX24110.1 - 0.0015 18.1 0.0 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAX24110.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAX24110.1 - 0.16 11.4 0.0 0.44 10.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Trypsin_2 PF13365.6 GAX24111.1 - 1.2e-05 26.2 0.1 2.7e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX24111.1 - 9.8e-05 22.3 1.2 0.0031 17.4 1.2 2.3 1 1 0 1 1 1 1 Trypsin Kazal_1 PF00050.21 GAX24111.1 - 0.0057 16.6 5.3 0.0093 16.0 3.9 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GAX24111.1 - 0.012 15.7 3.7 0.012 15.7 3.7 2.1 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DUF956 PF06115.11 GAX24111.1 - 0.13 12.0 0.2 0.28 10.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Peptidase_S46 PF10459.9 GAX24111.1 - 0.2 10.2 0.2 2.5 6.6 0.1 2.0 2 0 0 2 2 2 0 Peptidase S46 BRE1 PF08647.11 GAX24112.1 - 2.1 8.5 14.1 0.22 11.6 7.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase USP8_interact PF08941.10 GAX24112.1 - 6.9 6.4 10.1 0.7 9.7 5.6 1.6 2 0 0 2 2 2 0 USP8 interacting Trypsin PF00089.26 GAX24113.1 - 4e-08 33.3 0.1 1.9e-07 31.1 0.1 1.8 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX24113.1 - 1e-06 29.7 0.0 2.9e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 GAX24113.1 - 0.0051 15.5 2.8 0.5 9.0 0.3 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 GAX24113.1 - 0.015 14.5 1.4 0.027 13.7 0.2 1.8 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.26 GAX24114.1 - 3.1e-07 30.4 0.3 7.6e-07 29.2 0.3 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX24114.1 - 3.3e-05 24.8 0.0 7.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kazal_2 PF07648.15 GAX24114.1 - 0.0004 20.5 3.2 0.00075 19.6 3.2 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 GAX24114.1 - 0.00043 20.2 0.5 0.0009 19.2 0.5 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Trypsin PF00089.26 GAX24115.1 - 0.00011 22.1 0.5 0.00029 20.7 0.5 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX24115.1 - 0.0039 18.1 0.1 0.0087 17.0 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kazal_1 PF00050.21 GAX24115.1 - 0.13 12.3 2.7 0.4 10.7 2.7 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Trypsin_2 PF13365.6 GAX24116.1 - 0.00014 22.8 0.0 0.00032 21.6 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Kazal_1 PF00050.21 GAX24116.1 - 0.0009 19.2 0.4 0.0023 17.9 0.4 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GAX24116.1 - 0.0092 16.1 3.2 0.021 15.0 3.2 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Trypsin PF00089.26 GAX24116.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Trypsin Trypsin PF00089.26 GAX24117.1 - 4e-08 33.4 0.1 7.4e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX24117.1 - 6e-08 33.7 0.0 1.2e-07 32.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF31 PF01732.16 GAX24117.1 - 2.7e-05 23.9 0.1 4.4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 GAX24117.1 - 0.00041 20.2 1.1 0.0009 19.1 0.3 1.9 2 0 0 2 2 2 1 Peptidase S7, Flavivirus NS3 serine protease Kazal_2 PF07648.15 GAX24117.1 - 3.8 7.7 10.9 0.081 13.1 3.4 2.2 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 GAX24117.1 - 7.6 6.6 9.8 0.084 12.9 1.3 2.1 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Trypsin_2 PF13365.6 GAX24118.1 - 2.8e-05 25.1 0.0 5.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kazal_1 PF00050.21 GAX24118.1 - 0.00012 22.0 0.4 0.00033 20.6 0.4 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GAX24118.1 - 0.00023 21.2 2.0 0.00023 21.2 2.0 2.1 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Trypsin PF00089.26 GAX24118.1 - 0.004 17.0 0.2 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 Trypsin Beta_propel PF09826.9 GAX24119.1 - 1.6e-15 57.0 0.0 4.2e-15 55.6 0.0 1.6 1 1 0 1 1 1 1 Beta propeller domain Beta_propel PF09826.9 GAX24120.1 - 3e-40 138.6 0.1 4.1e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 Beta propeller domain EST1_DNA_bind PF10373.9 GAX24121.1 - 9.9e-23 81.0 0.8 2.2e-21 76.6 0.8 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 GAX24121.1 - 2.5e-07 31.4 0.0 1.2e-06 29.2 0.0 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_1 PF00515.28 GAX24121.1 - 0.0022 17.7 0.1 0.0067 16.2 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX24121.1 - 0.006 16.7 0.0 0.022 14.9 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX24121.1 - 0.026 14.6 0.1 0.096 12.9 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX24121.1 - 0.037 14.3 0.0 0.2 12.0 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX24121.1 - 0.039 14.6 0.2 0.14 12.8 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX24121.1 - 0.04 14.7 0.3 0.41 11.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX24121.1 - 0.14 12.6 0.2 49 4.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fucokinase PF07959.12 GAX24122.1 - 3.2e-76 256.9 0.0 5e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 GAX24122.1 - 6.8e-08 32.8 1.9 7.4e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAX24122.1 - 0.00036 20.7 0.2 0.002 18.3 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain DnaJ PF00226.31 GAX24123.1 - 7.8e-18 64.4 1.1 1.8e-17 63.2 1.1 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C3Hc3H PF13891.6 GAX24123.1 - 0.0025 18.1 35.0 0.56 10.6 0.7 5.6 4 1 0 5 5 5 5 Potential DNA-binding domain Zn_clus PF00172.18 GAX24123.1 - 0.041 14.0 29.0 2.7 8.2 0.4 5.7 5 0 0 5 5 5 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MetallophosN PF16371.5 GAX24123.1 - 0.089 13.1 0.0 1.3e+02 3.0 0.0 4.4 5 0 0 5 5 5 0 N terminal of Calcineurin-like phosphoesterase Myosin_head PF00063.21 GAX24125.1 - 4.7e-185 616.7 0.0 4.7e-185 616.7 0.0 2.6 2 1 1 3 3 3 1 Myosin head (motor domain) IQ PF00612.27 GAX24125.1 - 3.5e-11 41.9 4.3 0.0042 16.8 0.2 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Myosin_N PF02736.19 GAX24125.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain TMEM192 PF14802.6 GAX24125.1 - 0.11 11.5 2.5 16 4.5 4.3 2.3 2 0 0 2 2 2 0 TMEM192 family DUF4116 PF13475.6 GAX24125.1 - 0.16 11.8 0.8 6.8 6.5 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) AAA_16 PF13191.6 GAX24125.1 - 0.61 10.4 0.0 0.61 10.4 0.0 3.4 2 1 0 3 3 3 0 AAA ATPase domain V_ATPase_I PF01496.19 GAX24125.1 - 3.5 5.4 17.1 5.9 4.7 17.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IGPS PF00218.21 GAX24126.1 - 3.8e-18 65.6 0.9 1.7e-17 63.4 0.8 1.9 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase Bromodomain PF00439.25 GAX24127.1 - 3.1e-31 107.3 0.0 5.1e-15 55.3 0.0 2.7 2 0 0 2 2 2 2 Bromodomain HAT_KAT11 PF08214.11 GAX24127.1 - 2e-23 83.2 0.0 3.8e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Histone acetylation protein PHD PF00628.29 GAX24127.1 - 0.01 15.7 3.4 0.01 15.7 3.4 3.7 3 1 0 3 3 3 0 PHD-finger PHD_4 PF16866.5 GAX24127.1 - 0.022 14.9 1.4 0.022 14.9 1.4 3.4 4 0 0 4 4 4 0 PHD-finger TPR_1 PF00515.28 GAX24128.1 - 9.4e-05 22.1 0.0 0.026 14.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Arm PF00514.23 GAX24128.1 - 0.026 14.6 8.9 1.7 8.8 0.1 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TPR_2 PF07719.17 GAX24128.1 - 0.11 12.6 3.8 13 6.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX24128.1 - 0.23 11.6 1.4 0.66 10.1 0.3 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Fasciclin PF02469.22 GAX24129.1 - 7.8e-26 90.8 0.0 9.9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF1529 PF07485.11 GAX24129.1 - 0.12 12.2 0.0 14 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) Fasciclin PF02469.22 GAX24130.1 - 1.3e-48 164.4 0.0 4.2e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF5525 PF17663.1 GAX24130.1 - 0.017 13.2 6.1 0.024 12.7 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) HJURP_mid PF12346.8 GAX24130.1 - 0.044 14.2 0.8 2.6 8.5 0.1 2.7 2 1 1 3 3 3 0 Holliday junction recognition protein-associated repeat DEC-1_N PF04625.13 GAX24130.1 - 0.084 11.9 3.4 0.13 11.2 3.4 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AbbA_antirepres PF14156.6 GAX24130.1 - 0.18 11.7 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 Antirepressor AbbA YopE_N PF09020.10 GAX24130.1 - 2.6 8.3 4.7 10 6.4 4.6 2.0 1 1 0 1 1 1 0 YopE, N terminal MS_channel PF00924.18 GAX24131.1 - 2.1e-16 60.1 1.1 4.4e-16 59.0 1.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel MS_channel PF00924.18 GAX24132.1 - 6.2e-13 48.8 0.9 1.2e-12 47.9 0.9 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2207 PF09972.9 GAX24132.1 - 0.049 12.4 3.6 0.046 12.5 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Connexin PF00029.19 GAX24132.1 - 0.16 11.7 3.3 0.77 9.5 0.0 2.4 2 0 0 2 2 2 0 Connexin MS_channel PF00924.18 GAX24133.1 - 3.6e-13 49.5 0.7 7e-13 48.6 0.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2207 PF09972.9 GAX24133.1 - 0.051 12.3 3.1 0.059 12.1 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 GAX24133.1 - 0.19 12.1 1.2 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Orf78 (ac78) Connexin PF00029.19 GAX24133.1 - 0.9 9.3 4.6 0.34 10.6 0.9 2.2 1 1 1 2 2 2 0 Connexin Mito_carr PF00153.27 GAX24134.1 - 9.6e-07 28.6 1.0 0.0012 18.8 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein zf-RING_2 PF13639.6 GAX24135.1 - 4.9e-11 42.8 10.2 8.7e-11 42.0 10.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX24135.1 - 1.5e-07 31.1 10.9 2.8e-07 30.2 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX24135.1 - 2.5e-06 27.1 8.3 8.2e-06 25.5 8.3 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GAX24135.1 - 3.5e-06 27.0 4.7 7.2e-06 26.0 4.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GAX24135.1 - 5.1e-06 26.2 6.7 8.7e-06 25.5 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX24135.1 - 7.2e-05 23.0 11.2 0.00019 21.6 11.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX24135.1 - 0.00014 21.7 10.7 0.00024 20.9 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX24135.1 - 0.00085 18.9 8.9 0.0017 17.9 8.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAX24135.1 - 0.0016 18.4 10.6 0.003 17.5 10.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX24135.1 - 0.0021 18.0 4.4 0.014 15.4 4.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX24135.1 - 0.025 14.4 7.7 0.068 13.0 7.8 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 GAX24135.1 - 0.18 11.7 6.4 1.7 8.6 1.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 GAX24135.1 - 0.19 11.9 10.3 2.9 8.1 10.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 GAX24135.1 - 0.81 9.9 9.6 1.9 8.7 9.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 GAX24135.1 - 1.2 9.0 8.6 3.1 7.7 8.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 GAX24135.1 - 1.9 8.4 10.3 3.7 7.5 10.3 1.5 1 0 0 1 1 1 0 PHD-finger Tmemb_9 PF05434.11 GAX24135.1 - 3.2 7.6 5.4 5.2 7.0 0.1 3.0 2 1 1 3 3 3 0 TMEM9 RINGv PF12906.7 GAX24135.1 - 4.5 7.5 10.5 9.9 6.4 10.5 1.6 1 0 0 1 1 1 0 RING-variant domain Abhydrolase_6 PF12697.7 GAX24136.1 - 2.8e-15 57.5 0.2 6.1e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX24136.1 - 3e-08 33.6 0.1 2.2e-07 30.8 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX24136.1 - 0.0019 17.5 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DNA_photolyase PF00875.18 GAX24136.1 - 0.0058 16.7 0.0 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 DNA photolyase Dynein_C PF18199.1 GAX24136.1 - 0.083 12.1 0.2 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Dynein heavy chain C-terminal domain DUF1451 PF07295.11 GAX24136.1 - 0.089 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain KdpC PF02669.15 GAX24138.1 - 0.075 12.9 2.5 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 K+-transporting ATPase, c chain RVT_2 PF07727.14 GAX24140.1 - 2.4e-18 66.7 0.0 6.1e-18 65.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SF3b1 PF08920.10 GAX24140.1 - 0.075 13.5 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 rve PF00665.26 GAX24140.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Trehalase PF01204.18 GAX24141.1 - 8.8 5.0 12.1 2 7.1 8.8 1.5 2 0 0 2 2 2 0 Trehalase KCNQ2_u3 PF16642.5 GAX24142.1 - 1.9 9.5 6.2 1.6 9.8 3.5 2.1 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Fasciclin PF02469.22 GAX24143.1 - 1.9e-17 63.7 0.0 2.3e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain PqiA PF04403.13 GAX24144.1 - 5.8e-07 29.5 17.8 1.1e-06 28.6 5.5 2.6 2 0 0 2 2 2 2 Paraquat-inducible protein A DUF4349 PF14257.6 GAX24144.1 - 0.12 11.8 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HXXEE PF13787.6 GAX24144.1 - 9.8 7.0 8.4 23 5.8 4.4 2.8 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif HSF_DNA-bind PF00447.17 GAX24145.1 - 2.5e-14 53.6 1.5 5.8e-14 52.5 0.6 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Mago_nashi PF02792.14 GAX24146.1 - 0.12 12.5 0.1 0.5 10.5 0.1 2.0 1 0 0 1 1 1 0 Mago nashi protein DHDPS PF00701.22 GAX24149.1 - 3.7e-79 265.5 0.0 4e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HA PF03457.14 GAX24150.1 - 2.7e-16 59.7 2.1 2e-09 37.6 0.0 3.2 3 0 0 3 3 3 3 Helicase associated domain Chlamy_scaf PF09675.10 GAX24151.1 - 0.11 12.9 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) HHH_5 PF14520.6 GAX24151.1 - 0.13 12.9 0.0 0.73 10.5 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF4332 PF14229.6 GAX24151.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4332) CCDC-167 PF15188.6 GAX24152.1 - 0.034 14.5 1.8 0.053 13.9 1.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PetL PF05115.14 GAX24153.1 - 0.38 10.8 2.1 0.92 9.5 2.1 1.7 1 1 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Trypan_PARP PF05887.11 GAX24154.1 - 0.011 15.8 25.6 0.011 15.8 25.6 1.8 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF2868 PF11067.8 GAX24154.1 - 0.015 14.9 0.2 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TonB_N PF16031.5 GAX24154.1 - 5.8 7.4 28.0 23 5.5 28.0 1.9 1 1 0 1 1 1 0 TonB polyproline region Fibrillarin PF01269.17 GAX24155.1 - 9.6e-37 126.3 0.0 1.1e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin Fibrillarin PF01269.17 GAX24156.1 - 2.3e-14 53.0 0.0 3e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin VKOR PF07884.14 GAX24157.1 - 1.7e-19 70.2 5.1 2.3e-19 69.8 5.1 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Sec23_trunk PF04811.15 GAX24159.1 - 5.2e-12 45.9 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX24159.1 - 3.2e-05 23.7 0.0 0.00013 21.7 0.0 2.1 1 1 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GAX24159.1 - 0.00015 21.7 6.0 0.00015 21.7 6.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 GAX24159.1 - 0.016 16.0 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain zinc_ribbon_10 PF10058.9 GAX24159.1 - 0.034 13.9 2.9 0.076 12.8 2.9 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Vps36-NZF-N PF16988.5 GAX24159.1 - 0.048 13.1 2.2 0.068 12.6 0.2 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PhnA_Zn_Ribbon PF08274.12 GAX24159.1 - 0.077 13.0 2.7 0.25 11.4 2.7 1.8 1 0 0 1 1 1 0 PhnA Zinc-Ribbon FbpA PF05833.11 GAX24159.1 - 0.13 11.0 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) eIF3_N PF09440.10 GAX24160.1 - 1.9e-36 125.4 3.1 4.4e-36 124.3 0.3 2.8 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 GAX24160.1 - 1.8e-05 25.2 0.0 6.7e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 GAX24160.1 - 0.083 13.0 0.2 1 9.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp_protease_2 PF13650.6 GAX24161.1 - 9.6e-13 48.6 0.0 5.8e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAX24161.1 - 8.7e-07 29.4 0.0 0.0011 19.5 0.0 3.2 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease UCR_Fe-S_N PF10399.9 GAX24161.1 - 0.3 10.5 1.4 0.66 9.4 0.3 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 GAX24161.1 - 1.3 9.0 5.0 0.16 11.9 0.6 1.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence HSF_DNA-bind PF00447.17 GAX24162.1 - 1e-15 58.1 0.7 1.7e-15 57.4 0.7 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Bac_globin PF01152.21 GAX24163.1 - 2.7e-10 40.5 0.1 5.2e-10 39.5 0.1 1.5 1 1 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 GAX24163.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Protoglobin Mis14 PF08641.12 GAX24164.1 - 0.061 13.6 0.4 0.14 12.4 0.4 1.6 1 0 0 1 1 1 0 Kinetochore protein Mis14 like SlyX PF04102.12 GAX24164.1 - 0.079 13.6 2.2 0.28 11.8 0.5 2.6 2 0 0 2 2 2 0 SlyX HIP1_clath_bdg PF16515.5 GAX24164.1 - 1.2 9.8 6.5 40 4.9 0.3 3.2 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Vps51 PF08700.11 GAX24164.1 - 1.5 8.9 3.9 0.88 9.7 0.4 2.3 3 0 0 3 3 3 0 Vps51/Vps67 RRM_1 PF00076.22 GAX24165.1 - 6.9e-19 67.4 0.0 2.4e-05 24.0 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAX24165.1 - 0.00083 19.2 0.0 2.2 8.2 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_9 PF18444.1 GAX24165.1 - 0.0068 16.2 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Vps16_N PF04841.13 GAX24166.1 - 4.6e-50 170.6 0.0 1.5e-48 165.6 0.0 2.1 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 GAX24166.1 - 3.4e-33 115.0 1.6 7.2e-33 114.0 1.6 1.5 1 1 0 1 1 1 1 Vps16, C-terminal region DUF4375 PF14300.6 GAX24166.1 - 0.089 13.1 0.9 56 4.0 0.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4375) HSF_DNA-bind PF00447.17 GAX24167.1 - 1.3e-15 57.8 0.1 3.5e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding HTH_IclR PF09339.10 GAX24167.1 - 0.1 12.4 1.2 5.8 6.8 0.2 2.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain OHCU_decarbox PF09349.10 GAX24168.1 - 1.8e-38 132.5 0.1 2.4e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 OHCU decarboxylase Transthyretin PF00576.21 GAX24168.1 - 7e-29 100.7 0.0 1.3e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 HIUase/Transthyretin family DnaG_DnaB_bind PF08278.11 GAX24168.1 - 0.044 14.4 1.1 0.16 12.5 0.5 2.2 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding PH PF00169.29 GAX24169.1 - 4.4e-09 36.8 0.0 9.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 GAX24169.1 - 2.1e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 PH domain CRAL_TRIO PF00650.20 GAX24169.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.8 1 1 0 1 1 1 0 CRAL/TRIO domain PH_6 PF15406.6 GAX24169.1 - 0.015 15.6 0.4 0.04 14.2 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3556 PF12077.8 GAX24169.1 - 0.047 12.1 0.0 0.08 11.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Thioesterase PF00975.20 GAX24169.1 - 0.12 12.5 0.1 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Pkinase PF00069.25 GAX24170.1 - 3.5e-22 79.1 0.0 4.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24170.1 - 9e-17 61.2 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX24170.1 - 0.031 13.6 0.0 0.082 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like BET PF17035.5 GAX24170.1 - 0.14 12.3 0.2 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation NST1 PF13945.6 GAX24171.1 - 0.12 12.4 3.8 0.23 11.5 3.8 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator PWWP PF00855.17 GAX24172.1 - 1e-09 38.7 0.1 6.4e-09 36.1 0.1 2.4 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 GAX24172.1 - 1.8e-08 34.1 19.0 7.1e-06 25.8 2.0 3.9 4 0 0 4 4 4 2 PHD-finger Bromodomain PF00439.25 GAX24172.1 - 0.00011 22.2 0.2 0.00024 21.1 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Prok-RING_1 PF14446.6 GAX24172.1 - 0.0026 17.6 3.7 0.0026 17.6 3.7 4.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 PHD PF00628.29 GAX24173.1 - 2.1e-25 88.3 78.0 2.5e-08 33.7 5.4 7.9 7 1 1 8 8 7 5 PHD-finger FYRN PF05964.14 GAX24173.1 - 4.3e-20 71.3 0.0 1.1e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 GAX24173.1 - 6.2e-18 65.7 0.4 2.7e-16 60.4 0.2 3.2 2 1 0 2 2 2 1 SET domain Bromodomain PF00439.25 GAX24173.1 - 2.3e-12 46.8 0.1 5.7e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 GAX24173.1 - 3.9e-12 46.4 0.2 1.1e-11 45.0 0.2 1.8 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H PF13771.6 GAX24173.1 - 4.4e-11 42.9 7.9 4.4e-11 42.9 7.9 6.4 5 1 0 5 5 5 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAX24173.1 - 2.1e-09 37.5 3.5 2.1e-09 37.5 3.5 6.6 7 1 1 8 8 6 2 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 GAX24173.1 - 2.2e-05 24.3 13.3 5.4e-05 23.0 2.1 7.9 8 0 0 8 8 6 2 Prokaryotic RING finger family 1 FYRC PF05965.14 GAX24173.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus RAG2_PHD PF13341.6 GAX24173.1 - 0.082 13.0 0.1 0.082 13.0 0.1 3.9 5 0 0 5 5 5 0 RAG2 PHD domain N-SET PF11764.8 GAX24173.1 - 0.093 12.8 2.3 0.24 11.5 2.3 1.7 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N AT_hook PF02178.19 GAX24173.1 - 0.46 10.5 4.5 1.5 8.9 4.5 2.0 1 0 0 1 1 1 0 AT hook motif Ribosomal_60s PF00428.19 GAX24173.1 - 4.5 7.9 6.1 17 6.1 6.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein XRN_N PF03159.18 GAX24174.1 - 2.2e-82 276.1 0.0 3.1e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 GAX24174.1 - 6e-80 269.4 0.1 2.3e-51 175.2 0.3 2.2 2 0 0 2 2 2 2 Xrn1 helical domain Arm-DNA-bind_4 PF14657.6 GAX24174.1 - 0.12 12.1 3.3 0.1 12.4 0.6 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain HSF_DNA-bind PF00447.17 GAX24175.1 - 1.2e-09 38.7 2.3 3e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding TFIIA PF03153.13 GAX24175.1 - 0.026 14.5 16.6 0.033 14.2 16.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chloroa_b-bind PF00504.21 GAX24176.1 - 1.5e-35 123.1 0.3 2e-35 122.7 0.3 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EamA PF00892.20 GAX24177.1 - 4.9e-18 65.6 22.9 3.9e-10 40.0 4.5 3.1 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAX24177.1 - 0.029 13.6 2.0 3.5 6.7 0.3 2.3 2 0 0 2 2 2 0 Nucleotide-sugar transporter Methyltransf_11 PF08241.12 GAX24178.1 - 9.1e-12 45.5 0.0 4.9e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX24178.1 - 3.4e-10 40.5 0.0 1.5e-08 35.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX24178.1 - 3.2e-09 36.7 0.0 7.5e-08 32.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX24178.1 - 1.3e-05 25.9 0.0 2.9e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX24178.1 - 0.0071 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX24178.1 - 0.051 12.9 0.0 0.49 9.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAX24178.1 - 0.083 12.4 0.0 7.4 6.1 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 GAX24178.1 - 0.1 12.6 0.4 0.27 11.2 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain SDA1 PF05285.12 GAX24178.1 - 0.11 11.9 19.5 0.15 11.5 19.5 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAX24178.1 - 0.83 7.9 9.4 1.1 7.5 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAX24178.1 - 1.4 7.0 18.8 1.8 6.7 18.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1479 PF07350.12 GAX24179.1 - 1.7e-10 40.3 0.1 1.2e-07 30.9 0.3 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 GAX24179.1 - 0.0001 22.7 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) zf-LITAF-like PF10601.9 GAX24180.1 - 0.21 11.9 2.7 0.17 12.1 0.4 1.9 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain PKD PF00801.20 GAX24181.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 PKD domain Amino_oxidase PF01593.24 GAX24182.1 - 5.8e-65 220.3 0.0 1.4e-43 149.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX24182.1 - 1.9e-13 50.4 0.1 4.4e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX24182.1 - 1.9e-07 30.5 0.1 3.1e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAX24182.1 - 3.7e-07 30.0 0.4 7.1e-07 29.1 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAX24182.1 - 9.1e-06 25.3 0.1 3.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX24182.1 - 1.6e-05 24.3 0.1 3.1e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX24182.1 - 6.1e-05 21.9 0.1 0.00011 21.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 GAX24182.1 - 0.0001 21.7 0.3 0.00062 19.1 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 GAX24182.1 - 0.00027 21.4 0.2 0.00095 19.7 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX24182.1 - 0.00077 18.8 0.1 0.0014 17.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAX24182.1 - 0.008 15.5 0.1 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAX24182.1 - 0.036 14.1 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 GAX24182.1 - 0.076 12.1 0.3 0.12 11.4 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAX24182.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YjeF_N PF03853.15 GAX24182.1 - 0.15 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus TrkA_N PF02254.18 GAX24182.1 - 0.17 12.1 0.1 0.48 10.7 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain Sua5_yciO_yrdC PF01300.18 GAX24183.1 - 0.045 13.3 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Telomere recombination DAGAT PF03982.13 GAX24185.1 - 4.8e-28 97.9 0.0 6.2e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Geminin PF07412.12 GAX24185.1 - 0.78 9.5 1.7 1.4 8.6 1.7 1.3 1 0 0 1 1 1 0 Geminin Ras PF00071.22 GAX24187.1 - 9.2e-30 103.4 0.0 2.8e-26 92.0 0.0 2.7 2 1 0 2 2 2 2 Ras family Roc PF08477.13 GAX24187.1 - 6.8e-22 77.9 0.0 3.7e-21 75.6 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX24187.1 - 1e-11 44.6 0.0 1.3e-10 41.0 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX24187.1 - 2.7e-08 33.9 0.0 5.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX24187.1 - 2.5e-07 30.3 0.0 4.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 GAX24187.1 - 1.9e-05 24.9 0.1 0.00056 20.2 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX24187.1 - 0.0011 19.3 0.0 0.0017 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.21 GAX24187.1 - 0.014 14.9 0.0 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 GAX24187.1 - 0.044 13.9 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GAX24187.1 - 0.073 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 GAX24187.1 - 0.11 11.9 0.0 1.4 8.3 0.0 2.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit PAC4 PF16093.5 GAX24188.1 - 1e-12 48.1 0.0 2.6e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 PAP_assoc PF03828.19 GAX24190.1 - 4.8e-09 36.3 0.0 5.4e-07 29.7 0.0 2.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAX24190.1 - 1.9e-07 31.3 0.0 4.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF711 PF05167.12 GAX24191.1 - 8e-92 308.2 0.0 1e-91 307.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) PAP_central PF04928.17 GAX24192.1 - 2.4e-60 203.6 0.0 6e-60 202.3 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAX24192.1 - 1e-10 41.5 0.3 8.7e-08 32.0 0.0 2.9 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAX24192.1 - 0.00022 21.4 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ku_C PF03730.14 GAX24192.1 - 0.36 11.6 6.1 1.6 9.5 5.9 2.1 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm PIEZO PF15917.5 GAX24192.1 - 8.5 5.8 7.5 14 5.1 7.5 1.3 1 0 0 1 1 1 0 Piezo MFS_5 PF05631.14 GAX24193.1 - 1.3e-37 129.6 11.2 4.1e-34 118.1 2.8 2.9 2 2 1 3 3 3 2 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAX24193.1 - 1.4e-08 34.0 21.4 5.6e-08 32.1 6.7 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Mid1 PF12929.7 GAX24193.1 - 0.058 12.6 3.1 0.088 12.0 3.1 1.1 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component Adeno_E3 PF06040.11 GAX24193.1 - 0.31 11.2 5.3 4.5 7.5 0.3 3.2 3 0 0 3 3 3 0 Adenovirus E3 protein LRR_6 PF13516.6 GAX24194.1 - 4.4e-33 110.5 15.2 9.3e-05 22.2 0.0 10.7 10 0 0 10 10 10 9 Leucine Rich repeat LRR_4 PF12799.7 GAX24194.1 - 2.7e-11 43.5 6.9 0.0017 18.8 0.1 6.8 3 2 4 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX24194.1 - 1.9e-07 30.7 2.3 28 5.8 0.0 8.4 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 GAX24194.1 - 3e-07 30.1 12.3 0.04 13.7 1.0 6.7 6 4 0 6 6 6 4 Leucine rich repeat HAD_2 PF13419.6 GAX24195.1 - 3.6e-08 33.7 0.0 4.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX24195.1 - 1.2e-06 28.9 0.0 1.6e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX24195.1 - 7.3e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like zf-RING_2 PF13639.6 GAX24196.1 - 1e-10 41.8 15.3 1.9e-10 40.9 15.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX24196.1 - 8e-07 28.7 12.7 1.7e-06 27.6 12.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAX24196.1 - 1.3e-05 25.4 12.9 3.4e-05 24.1 12.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX24196.1 - 5e-05 23.2 14.2 8.9e-05 22.4 14.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX24196.1 - 8.3e-05 22.5 10.6 0.00016 21.6 10.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX24196.1 - 0.00048 19.9 14.2 0.0009 19.1 14.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX24196.1 - 0.0014 18.4 14.5 0.0023 17.7 14.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX24196.1 - 0.013 15.4 11.0 0.024 14.5 11.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAX24196.1 - 0.018 14.9 10.6 0.031 14.1 10.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX24196.1 - 0.032 14.3 7.8 0.085 12.9 7.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX24196.1 - 0.38 10.4 10.8 0.76 9.4 10.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ABA_GPCR PF12430.8 GAX24197.1 - 3.5e-15 56.2 6.0 3.5e-15 56.2 6.0 2.1 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 GAX24197.1 - 1.2e-10 41.3 0.0 5.2e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal LMBR1 PF04791.16 GAX24197.1 - 0.00061 18.8 0.0 0.00061 18.8 0.0 2.9 3 2 0 3 3 3 1 LMBR1-like membrane protein DUF2353 PF09789.9 GAX24197.1 - 0.055 12.8 0.1 0.082 12.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) AAA PF00004.29 GAX24198.1 - 3.8e-39 134.1 0.0 7.3e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAX24198.1 - 2.3e-07 30.7 0.0 1.7e-06 27.9 0.0 2.6 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 GAX24198.1 - 3.2e-07 30.0 0.0 7.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAX24198.1 - 4.1e-06 26.8 0.1 2.1e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX24198.1 - 4.7e-06 26.4 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX24198.1 - 0.00034 21.0 0.2 0.0026 18.2 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 GAX24198.1 - 0.00089 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 GAX24198.1 - 0.0052 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAX24198.1 - 0.011 16.0 2.3 0.058 13.7 0.3 3.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX24198.1 - 0.013 15.0 0.7 1.2 8.7 0.1 3.1 1 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 GAX24198.1 - 0.027 15.0 0.2 0.084 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAX24198.1 - 0.052 13.6 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX24198.1 - 0.063 13.7 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.17 GAX24198.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAX24198.1 - 0.09 12.1 0.1 0.28 10.5 0.1 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 GAX24198.1 - 0.18 11.1 0.4 2.5 7.4 0.1 2.7 2 1 1 3 3 3 0 KaiC Sigma54_activat PF00158.26 GAX24198.1 - 0.19 11.4 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain WBS_methylT PF12589.8 GAX24200.1 - 1.2e-14 54.8 11.0 1.2e-14 54.8 11.0 2.0 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 GAX24200.1 - 4.4e-12 46.5 0.0 1.3e-10 41.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX24200.1 - 3.8e-11 43.6 0.1 8e-06 26.5 0.1 2.7 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAX24200.1 - 2.9e-09 37.6 0.0 5.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX24200.1 - 2.1e-05 24.4 0.0 4.7e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX24200.1 - 0.00037 20.3 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GAX24200.1 - 0.0012 18.6 0.0 1.4 8.6 0.0 2.4 2 1 0 2 2 2 2 DNA methylase Ubie_methyltran PF01209.18 GAX24200.1 - 0.014 14.8 0.1 0.079 12.3 0.0 2.0 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GAX24200.1 - 0.015 15.3 0.1 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 GAX24200.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 GAX24200.1 - 0.031 14.6 0.0 0.097 13.0 0.0 1.8 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF4611 PF15387.6 GAX24200.1 - 2 8.7 8.3 0.98 9.7 5.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-CHY PF05495.12 GAX24201.1 - 1.5e-12 47.8 11.7 1.5e-12 47.8 11.7 3.8 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 GAX24201.1 - 3.1e-08 33.8 5.9 3.1e-08 33.8 5.9 4.2 3 1 1 4 4 4 1 Ring finger domain Hemerythrin PF01814.23 GAX24201.1 - 3e-05 24.7 13.0 0.00011 22.8 7.3 2.7 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain zf-RING_UBOX PF13445.6 GAX24201.1 - 6.7e-05 22.8 5.9 6.7e-05 22.8 5.9 2.9 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX24201.1 - 0.0064 16.3 0.6 0.0064 16.3 0.6 4.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 DUF521 PF04412.13 GAX24201.1 - 0.0091 14.8 0.7 0.022 13.5 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF521) Glycos_trans_3N PF02885.17 GAX24201.1 - 0.073 12.9 0.2 5 7.0 0.1 2.8 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Syntaxin_2 PF14523.6 GAX24201.1 - 0.36 11.2 3.0 14 6.1 0.1 2.7 2 0 0 2 2 2 0 Syntaxin-like protein RAC_head PF16717.5 GAX24201.1 - 2.8 9.0 8.3 0.41 11.7 0.2 3.2 3 1 1 4 4 4 0 Ribosome-associated complex head domain zf-RING_11 PF17123.5 GAX24201.1 - 7.6 6.4 13.9 0.22 11.3 4.4 3.3 3 0 0 3 3 3 0 RING-like zinc finger DUF3246 PF11596.8 GAX24202.1 - 0.012 15.1 0.9 0.028 13.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TraW_N PF12477.8 GAX24202.1 - 0.4 10.7 1.8 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal Tom22 PF04281.13 GAX24202.1 - 3.1 7.6 5.5 0.28 11.0 0.3 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 PDZ_6 PF17820.1 GAX24203.1 - 8.9e-06 25.5 0.0 3.5 7.5 0.0 4.6 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 GAX24203.1 - 0.00016 22.0 0.0 13 6.2 0.0 4.2 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 GAX24203.1 - 0.095 13.0 0.6 13 6.2 0.0 4.2 5 0 0 5 5 5 0 PDZ domain SYCE1 PF15233.6 GAX24203.1 - 0.43 10.6 6.2 0.17 11.9 1.6 2.7 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 GIT1_C PF12205.8 GAX24203.1 - 2.7 8.1 6.0 2.7 8.1 3.0 2.6 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Myb_DNA-bind_6 PF13921.6 GAX24205.1 - 1.7e-15 57.0 16.3 2e-06 28.0 0.1 5.3 5 1 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAX24205.1 - 0.0033 17.6 7.6 3.5 7.9 0.0 5.0 5 0 0 5 5 5 2 Myb-like DNA-binding domain SAM_decarbox PF01536.16 GAX24205.1 - 0.023 13.7 0.4 0.047 12.7 0.4 1.5 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Atg29_N PF18388.1 GAX24205.1 - 0.066 13.0 2.9 0.11 12.4 0.1 2.6 3 0 0 3 3 3 0 Atg29 N-terminal domain SLIDE PF09111.10 GAX24205.1 - 0.79 9.8 5.4 12 6.0 0.0 3.8 3 1 1 4 4 4 0 SLIDE BRF1 PF07741.13 GAX24205.1 - 6.9 7.1 8.8 2.9 8.3 1.3 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TauD PF02668.16 GAX24206.1 - 1.4e-33 116.8 0.6 2.4e-33 116.1 0.6 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2700 PF10912.8 GAX24207.1 - 0.058 13.4 0.7 0.1 12.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) RXLR PF16810.5 GAX24207.1 - 8.5 6.8 8.9 2.7e+03 -1.3 8.9 3.0 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Pentapeptide_4 PF13599.6 GAX24208.1 - 6.1e-17 61.6 5.8 3.9e-07 30.1 0.1 2.8 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 GAX24208.1 - 2e-16 59.3 8.2 2e-08 33.7 0.9 3.5 3 1 2 5 5 5 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 GAX24208.1 - 4.4e-11 42.8 8.4 1.7e-05 24.9 2.0 2.7 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) Peptidase_C97 PF05903.14 GAX24209.1 - 0.031 14.1 0.5 0.072 12.9 0.5 1.5 1 1 0 1 1 1 0 PPPDE putative peptidase domain A_deaminase PF00962.22 GAX24210.1 - 8.4e-53 179.8 0.4 1.4e-46 159.4 0.3 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 GAX24210.1 - 0.0047 16.4 0.1 0.0097 15.4 0.1 1.5 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAX24210.1 - 0.051 12.9 0.2 0.15 11.4 0.2 1.7 1 1 0 1 1 1 0 Amidohydrolase family Nrf1_activ_bdg PF10492.9 GAX24211.1 - 0.48 11.1 3.4 2.3 9.0 3.0 2.3 1 1 1 2 2 2 0 Nrf1 activator activation site binding domain VIT1 PF01988.19 GAX24211.1 - 2.5 7.9 4.7 0.54 10.1 0.5 2.0 2 0 0 2 2 2 0 VIT family ABC_membrane PF00664.23 GAX24212.1 - 1.9e-52 178.6 11.1 3.7e-52 177.7 11.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAX24212.1 - 1.5e-33 116.2 0.0 2.6e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAX24212.1 - 4.5e-06 27.1 0.0 1.2e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 GAX24212.1 - 0.00019 20.4 0.1 0.00036 19.5 0.1 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 GAX24212.1 - 0.00083 19.3 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAX24212.1 - 0.0016 18.7 0.1 0.0079 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 GAX24212.1 - 0.0022 17.4 1.8 0.037 13.5 1.8 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 GAX24212.1 - 0.039 14.4 0.1 0.25 11.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAX24212.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 GAX24212.1 - 0.087 13.1 0.3 1.1 9.6 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 GAX24212.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 GAX24212.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mal_decarbox_Al PF16957.5 GAX24213.1 - 0.022 13.1 0.0 0.035 12.4 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter TPR_2 PF07719.17 GAX24213.1 - 0.057 13.6 0.2 6.3 7.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Cullin PF00888.22 GAX24214.1 - 3.9e-22 78.6 6.3 5.3e-22 78.2 0.5 2.5 2 1 1 3 3 3 2 Cullin family ANAPC2 PF08672.11 GAX24214.1 - 1.5e-21 76.7 0.2 6.6e-21 74.6 0.1 2.3 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Flavodoxin_NdrI PF07972.11 GAX24214.1 - 0.098 12.8 0.5 2.5 8.3 0.0 2.9 3 1 0 3 3 3 0 NrdI Flavodoxin like XPC-binding PF09280.11 GAX24214.1 - 3.3 7.5 13.7 11 5.8 2.3 3.9 3 0 0 3 3 3 0 XPC-binding domain LRS4 PF10422.9 GAX24215.1 - 0.055 13.0 1.3 0.073 12.6 1.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Nucleo_P87 PF07267.11 GAX24215.1 - 0.22 10.3 5.6 0.28 10.0 5.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 GAX24215.1 - 0.37 10.1 12.1 0.47 9.7 12.1 1.2 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 GAX24215.1 - 0.86 9.2 9.8 1.1 8.8 9.8 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GAX24215.1 - 0.9 7.6 18.6 1.2 7.1 18.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 GAX24215.1 - 2.6 7.9 9.2 3.7 7.4 9.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 GAX24215.1 - 3.3 5.8 13.0 4.4 5.4 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GAX24215.1 - 3.7 7.2 5.2 7 6.3 5.2 1.4 1 0 0 1 1 1 0 FAM176 family Tom22 PF04281.13 GAX24216.1 - 0.069 12.9 2.0 0.12 12.2 2.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 GCIP PF13324.6 GAX24216.1 - 1.4 8.4 5.1 1.9 8.0 5.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GAX24216.1 - 4.7 5.2 9.8 6.8 4.7 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF179 PF02622.15 GAX24217.1 - 2.7e-32 112.0 0.1 2.1e-21 76.6 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized ACR, COG1678 OTCace PF00185.24 GAX24217.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain KH_1 PF00013.29 GAX24218.1 - 4.6e-64 212.2 43.0 8.1e-10 38.4 1.5 12.6 12 0 0 12 12 12 10 KH domain KH_2 PF07650.17 GAX24218.1 - 7.3e-17 61.0 31.9 0.00027 20.7 0.9 9.4 6 2 3 9 9 9 5 KH domain SLS PF14611.6 GAX24218.1 - 2.3e-16 60.3 36.7 0.013 15.4 0.1 10.3 3 2 6 11 11 11 6 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 GAX24218.1 - 4.5e-11 42.5 16.5 0.028 14.3 0.2 8.4 7 1 0 7 7 7 4 KH domain KH_5 PF13184.6 GAX24218.1 - 0.00077 19.5 17.8 0.94 9.6 0.1 7.6 8 0 0 8 8 8 1 NusA-like KH domain Secretin_N PF03958.17 GAX24218.1 - 0.047 14.1 2.3 10 6.6 0.0 5.1 5 0 0 5 5 5 0 Bacterial type II/III secretion system short domain CLZ PF16526.5 GAX24218.1 - 0.095 13.1 7.5 0.11 12.9 0.6 4.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 GAX24218.1 - 0.23 11.4 0.1 0.23 11.4 0.1 4.8 4 1 0 4 4 4 0 Prefoldin subunit MOEP19 PF16005.5 GAX24218.1 - 0.93 9.5 4.9 9.4 6.3 0.0 4.5 6 0 0 6 6 6 0 KH-like RNA-binding domain Ribosomal_L6 PF00347.23 GAX24218.1 - 3.6 8.3 20.2 6.2 7.6 0.1 7.8 9 0 0 9 9 9 0 Ribosomal protein L6 FG-GAP_2 PF14312.6 GAX24219.1 - 4.5e-10 39.6 36.9 0.0081 16.4 0.4 7.6 7 0 0 7 7 7 5 FG-GAP repeat BPL_C PF02237.17 GAX24219.1 - 0.062 13.2 1.8 0.53 10.2 0.1 3.1 3 0 0 3 3 3 0 Biotin protein ligase C terminal domain KH_1 PF00013.29 GAX24220.1 - 0.053 13.3 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 KH domain Ysc84 PF04366.12 GAX24220.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Las17-binding protein actin regulator DUF839 PF05787.13 GAX24221.1 - 1.4e-09 37.7 9.3 6.1e-06 25.7 4.4 3.2 1 1 1 3 3 3 3 Bacterial protein of unknown function (DUF839) DUF839 PF05787.13 GAX24222.1 - 2.5e-10 40.2 13.6 3.3e-06 26.6 7.0 3.1 1 1 1 3 3 3 3 Bacterial protein of unknown function (DUF839) Cu-binding_MopE PF11617.8 GAX24222.1 - 1.3e-09 38.0 16.9 1.3e-09 38.0 16.9 2.7 3 0 0 3 3 3 1 Putative metal-binding motif PT PF04886.12 GAX24222.1 - 0.074 12.6 46.7 0.4 10.3 12.0 3.0 2 1 0 2 2 2 0 PT repeat Trypan_PARP PF05887.11 GAX24222.1 - 1.1 9.2 12.7 2.3 8.2 12.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ECH_1 PF00378.20 GAX24223.1 - 1.5e-42 145.7 0.0 1.7e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX24223.1 - 1.2e-13 51.3 0.0 1.8e-13 50.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Toxin_35 PF10530.9 GAX24224.1 - 0.00026 20.9 3.3 0.00026 20.9 3.3 9.1 3 3 6 9 9 9 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold VWD PF00094.25 GAX24224.1 - 0.0011 19.3 1.5 0.0085 16.4 1.5 2.3 1 1 0 1 1 1 1 von Willebrand factor type D domain DnaJ_C PF01556.18 GAX24225.1 - 0.0027 17.8 0.0 8 6.5 0.0 3.2 1 1 1 2 2 2 2 DnaJ C terminal domain PP-binding PF00550.25 GAX24226.1 - 7.7e-17 61.4 0.9 9.8e-17 61.1 0.9 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAX24226.1 - 2e-07 31.2 1.6 2.8e-07 30.7 1.6 1.3 1 1 0 1 1 1 1 Acyl-carrier PRD PF00874.20 GAX24226.1 - 0.16 12.3 0.3 0.26 11.6 0.3 1.2 1 0 0 1 1 1 0 PRD domain HSF_DNA-bind PF00447.17 GAX24228.1 - 4.2e-16 59.3 1.5 4.6e-16 59.2 0.2 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding HTH_9 PF08221.11 GAX24229.1 - 5.3e-13 48.9 1.4 2.1e-08 34.1 0.1 3.9 3 1 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 GAX24229.1 - 2.1e-06 27.5 1.2 0.00053 19.8 0.1 3.4 4 0 0 4 4 4 2 TFIIE alpha subunit Lact-deh-memb PF09330.11 GAX24230.1 - 4.9e-51 173.8 0.0 1.8e-50 172.0 0.0 2.0 2 1 0 2 2 2 1 D-lactate dehydrogenase, membrane binding FAD_binding_4 PF01565.23 GAX24230.1 - 3.5e-11 43.0 0.0 8.3e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GAX24230.1 - 0.00015 21.5 0.7 0.2 11.3 1.4 3.3 2 1 0 2 2 2 2 FAD linked oxidases, C-terminal domain DSHCT PF08148.12 GAX24231.1 - 3.6e-13 49.5 0.1 3.1e-12 46.5 0.0 2.7 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 GAX24231.1 - 6.9e-07 29.2 0.0 2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX24231.1 - 1.1e-06 28.9 0.0 1.2e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX24231.1 - 0.029 14.4 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 GAX24232.1 - 2.9e-20 73.2 0.0 5.5e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX24232.1 - 1.7e-08 34.5 3.8 2.5e-08 33.9 3.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF87 PF01935.17 GAX24232.1 - 0.0006 20.0 0.2 0.0013 18.9 0.1 1.5 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 GAX24232.1 - 0.018 15.2 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 GAX24232.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX24232.1 - 0.04 13.7 0.4 0.099 12.4 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 GAX24232.1 - 0.052 13.0 2.2 0.21 11.0 0.1 2.5 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 GAX24232.1 - 0.085 12.8 0.1 22 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Abhydrolase_6 PF12697.7 GAX24233.1 - 5.2e-13 50.1 0.3 5.2e-13 50.1 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX24233.1 - 1e-12 48.2 0.0 6e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX24233.1 - 3e-10 39.8 0.0 3.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAX24233.1 - 0.0021 17.9 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 GAX24233.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_8 PF06259.12 GAX24233.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase NGP1NT PF08153.12 GAX24234.1 - 6.8e-39 133.0 0.7 1.5e-38 131.9 0.7 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 GAX24234.1 - 1.6e-17 63.6 0.1 2.6e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX24234.1 - 1.1e-06 28.3 0.0 0.00017 21.2 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX24234.1 - 2.2e-05 24.4 0.0 7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase cobW PF02492.19 GAX24234.1 - 0.0078 15.8 0.3 1 8.9 0.0 3.2 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 GAX24234.1 - 0.023 14.2 0.0 3.4 7.2 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Arf PF00025.21 GAX24234.1 - 0.024 14.1 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 GAX24234.1 - 0.026 14.6 5.9 0.36 10.9 0.2 4.0 4 1 1 5 5 5 0 Dynamin family Roc PF08477.13 GAX24234.1 - 0.031 14.5 0.0 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase His_Phos_1 PF00300.22 GAX24235.1 - 6e-15 55.5 0.0 8.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) IBN_N PF03810.19 GAX24236.1 - 3e-10 39.9 0.5 2.1e-09 37.1 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain UCH PF00443.29 GAX24237.1 - 3.7e-41 141.3 0.0 4.9e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 GAX24237.1 - 2.2e-13 49.8 0.3 7.4e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 GAX24237.1 - 5.5e-09 36.1 0.1 1.2e-05 25.0 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAX24237.1 - 3.8e-07 30.3 0.0 1.4e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 GAX24237.1 - 8.2e-05 22.3 0.1 0.00021 21.0 0.1 1.7 1 0 0 1 1 1 1 Variant UBP zinc finger Glyco_hydro81C PF17652.1 GAX24238.1 - 1.8e-69 234.6 0.1 3.9e-69 233.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAX24238.1 - 4.5e-14 52.3 0.1 1.2e-13 51.0 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain WD40_4 PF16300.5 GAX24239.1 - 4.4e-18 64.9 0.3 8.1e-18 64.0 0.3 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 GAX24239.1 - 5.3e-16 58.2 0.0 1.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 GAX24239.1 - 2.5e-14 53.4 4.3 0.0004 21.1 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX24239.1 - 1.3e-08 35.0 0.0 0.026 14.8 0.0 4.3 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF745 PF05335.13 GAX24239.1 - 0.0026 17.5 1.7 0.0042 16.8 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) CCDC144C PF14915.6 GAX24239.1 - 0.0063 15.7 3.0 0.0089 15.2 3.0 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region ATG16 PF08614.11 GAX24239.1 - 0.015 15.5 1.7 0.022 15.0 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 GAX24239.1 - 0.017 15.2 1.4 0.028 14.4 1.4 1.3 1 0 0 1 1 1 0 Laminin Domain II DHR10 PF18595.1 GAX24239.1 - 0.019 15.0 3.3 0.031 14.4 3.3 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tmemb_cc2 PF10267.9 GAX24239.1 - 0.03 13.5 0.1 0.041 13.0 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Spc7 PF08317.11 GAX24239.1 - 0.048 12.5 5.1 0.072 12.0 5.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 GAX24239.1 - 0.053 13.8 0.9 0.1 12.9 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Nup160 PF11715.8 GAX24239.1 - 0.16 10.6 0.0 0.36 9.4 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Fzo_mitofusin PF04799.13 GAX24239.1 - 0.25 10.9 1.5 0.37 10.3 1.5 1.2 1 0 0 1 1 1 0 fzo-like conserved region Borrelia_P83 PF05262.11 GAX24239.1 - 0.25 9.8 5.1 0.39 9.2 5.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.14 GAX24239.1 - 0.38 11.1 6.6 0.64 10.3 6.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NBP1 PF08537.10 GAX24239.1 - 0.46 9.9 3.2 0.63 9.4 3.2 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Exonuc_VII_S PF02609.16 GAX24239.1 - 1.3 9.2 6.3 2.5 8.2 6.3 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit XhlA PF10779.9 GAX24239.1 - 3.8 7.8 5.9 6.4 7.1 5.9 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF676 PF05057.14 GAX24240.1 - 1.8e-07 30.9 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAX24240.1 - 3.7e-07 30.1 0.0 1.2e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 GAX24240.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 GAX24240.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 GAX24240.1 - 0.0081 16.8 0.4 0.041 14.5 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 GAX24240.1 - 0.056 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 GAX24240.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 GAX24240.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pep_deformylase PF01327.21 GAX24242.1 - 5.7e-50 169.0 0.0 6.8e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase LPD16 PF18830.1 GAX24242.1 - 0.14 12.1 0.1 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 16 GST_N_3 PF13417.6 GAX24243.1 - 2.6e-09 37.3 0.1 6e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAX24243.1 - 3.8e-08 33.4 0.1 7.2e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GAX24243.1 - 3.7e-06 26.9 0.0 8.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAX24243.1 - 1.8e-05 24.9 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX24243.1 - 0.00044 20.5 0.0 0.00071 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAX24243.1 - 0.00095 19.9 0.2 0.0022 18.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain HEAT_2 PF13646.6 GAX24244.1 - 4.5e-23 81.4 4.2 1.6e-12 47.6 1.3 3.5 2 1 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 GAX24244.1 - 1.9e-17 62.1 6.5 0.0069 17.0 0.2 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 GAX24244.1 - 6.4e-05 22.9 5.0 1.9 9.0 0.3 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 GAX24244.1 - 0.00014 22.2 0.7 6.8 7.3 0.0 4.9 4 1 1 5 5 5 2 HEAT-like repeat Phe_hydrox_dim PF07976.12 GAX24244.1 - 0.15 12.1 0.1 2.3 8.2 0.0 2.3 2 1 0 2 2 2 0 Phenol hydroxylase, C-terminal dimerisation domain Syntaxin PF00804.25 GAX24245.1 - 1.8e-33 115.9 13.1 2.3e-33 115.6 13.1 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 GAX24245.1 - 2.3e-10 40.3 2.3 5.9e-10 39.0 2.3 1.7 1 0 0 1 1 1 1 SNARE domain Pepsin-I3 PF06394.13 GAX24245.1 - 0.0042 17.2 0.8 0.017 15.3 0.8 2.1 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain Syntaxin_2 PF14523.6 GAX24245.1 - 0.14 12.6 17.6 0.091 13.1 14.3 2.4 2 2 0 2 2 2 0 Syntaxin-like protein Herpes_US9 PF06072.11 GAX24245.1 - 0.15 11.9 0.7 0.51 10.2 0.5 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 HigB-like_toxin PF05015.13 GAX24245.1 - 0.83 10.1 4.0 0.92 10.0 0.3 2.8 2 2 1 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB T2SSF PF00482.23 GAX24245.1 - 1.5 8.8 6.5 4.9 7.1 1.0 3.0 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Equine_IAV_S2 PF06502.11 GAX24245.1 - 8.7 6.5 8.1 9.8 6.4 1.9 2.6 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein Ank_2 PF12796.7 GAX24246.1 - 6.7e-42 142.0 9.6 3.2e-12 46.9 0.0 5.5 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX24246.1 - 2e-34 117.5 3.4 8.2e-09 35.8 0.1 7.7 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX24246.1 - 4.1e-28 94.3 5.4 0.002 18.4 0.0 9.7 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 GAX24246.1 - 5.6e-28 96.6 7.6 3.4e-07 30.4 0.2 7.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 GAX24246.1 - 2.9e-23 81.2 16.4 0.0018 18.6 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat MATH PF00917.26 GAX24246.1 - 1.8e-12 47.4 0.0 7.1e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 MATH domain SRP54 PF00448.22 GAX24248.1 - 1.3e-71 240.3 4.7 1.2e-63 214.3 0.2 3.0 2 1 1 3 3 3 2 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAX24248.1 - 2.3e-22 79.4 6.6 2.3e-22 79.4 6.6 3.3 4 0 0 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 GAX24248.1 - 5.1e-15 55.4 1.0 1.8e-14 53.7 0.2 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 GAX24248.1 - 2.7e-05 23.5 0.1 0.0023 17.2 0.1 2.4 1 1 1 2 2 2 1 Zeta toxin CbiA PF01656.23 GAX24248.1 - 8.6e-05 22.6 0.0 0.0017 18.4 0.0 2.9 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 GAX24248.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAX24248.1 - 0.019 15.1 0.2 0.078 13.1 0.0 2.2 3 1 0 3 3 2 0 AAA domain APS_kinase PF01583.20 GAX24248.1 - 0.022 14.7 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 GAX24248.1 - 0.046 14.0 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX24248.1 - 0.046 14.3 0.2 0.13 12.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAX24248.1 - 0.14 11.8 0.2 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.6 GAX24248.1 - 0.14 11.7 2.6 1.8 8.1 2.6 2.6 1 1 0 1 1 1 0 AAA domain Rx_N PF18052.1 GAX24248.1 - 0.19 12.0 1.6 8.5 6.7 0.0 3.7 4 1 1 5 5 4 0 Rx N-terminal domain ArsA_ATPase PF02374.15 GAX24248.1 - 3 6.9 7.6 9.3 5.3 0.0 3.9 3 1 0 4 4 4 0 Anion-transporting ATPase NUDIX PF00293.28 GAX24249.1 - 7.3e-10 39.0 0.1 1.1e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain OppC_N PF12911.7 GAX24249.1 - 0.017 15.1 0.6 0.031 14.3 0.0 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C PI3_PI4_kinase PF00454.27 GAX24250.1 - 3.4e-30 105.7 0.0 7.9e-30 104.5 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 GAX24250.1 - 0.0052 16.5 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Serinc PF03348.15 GAX24251.1 - 2.2e-74 251.0 3.1 2.6e-74 250.7 3.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) SLT_beta PF02258.16 GAX24251.1 - 0.012 15.7 0.2 0.031 14.3 0.2 1.7 1 0 0 1 1 1 0 Shiga-like toxin beta subunit DUF2649 PF10854.8 GAX24251.1 - 0.038 14.3 1.6 2.9 8.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) PAS PF00989.25 GAX24252.1 - 3.4e-07 30.2 0.0 1.2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 GAX24252.1 - 4.7e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAX24252.1 - 7.1e-06 26.2 0.0 2.1e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 GAX24252.1 - 0.00027 20.9 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain DUF4570 PF15134.6 GAX24252.1 - 0.061 13.3 8.4 0.055 13.5 2.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) bZIP_2 PF07716.15 GAX24252.1 - 2.2 8.4 12.9 0.44 10.7 8.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Tom22 PF04281.13 GAX24253.1 - 4.5e-06 26.5 0.0 5.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 U-box PF04564.15 GAX24254.1 - 8.9e-12 45.0 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain C2 PF00168.30 GAX24254.1 - 1e-07 32.2 0.0 6.8e-06 26.3 0.0 2.4 1 1 1 2 2 2 1 C2 domain zf-Nse PF11789.8 GAX24254.1 - 4e-05 23.3 0.0 7.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 GAX24254.1 - 0.026 14.7 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 GAX24254.1 - 0.077 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger RRN3 PF05327.11 GAX24255.1 - 2e-84 284.1 3.1 2e-84 284.1 3.1 2.6 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GAX24255.1 - 1.5 7.0 8.3 0.8 7.8 6.5 1.4 2 0 0 2 2 2 0 Nop14-like family FKBP_C PF00254.28 GAX24256.1 - 1.4e-18 67.0 0.1 2.2e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AIRC PF00731.20 GAX24257.1 - 1.9e-12 47.0 3.9 1.9e-12 47.0 3.9 2.1 2 0 0 2 2 2 1 AIR carboxylase AIF_C PF14721.6 GAX24257.1 - 0.12 12.8 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RTP1_C1 PF10363.9 GAX24258.1 - 3.2e-23 82.0 0.9 1.4e-22 80.0 0.1 2.6 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 GAX24258.1 - 0.033 13.8 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Unstab_antitox PF09720.10 GAX24258.1 - 5.9 7.0 7.4 11 6.2 0.2 3.4 3 0 0 3 3 3 0 Putative addiction module component Csm1_N PF18504.1 GAX24259.1 - 4.2 7.8 6.6 0.28 11.6 1.1 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain SF3b1 PF08920.10 GAX24260.1 - 6.5e-27 94.4 16.6 8.5e-24 84.3 16.6 3.6 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 GAX24260.1 - 7.6e-12 45.5 1.7 0.3 11.5 0.0 6.8 6 0 0 6 6 6 3 HEAT repeats HEAT PF02985.22 GAX24260.1 - 1.7e-07 30.9 10.9 6 7.4 0.0 9.1 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 GAX24260.1 - 4.6e-07 30.2 2.9 0.083 13.4 0.0 7.1 7 1 1 8 8 8 1 HEAT-like repeat NUC173 PF08161.12 GAX24260.1 - 9.8e-05 22.1 0.7 0.78 9.4 0.0 4.2 5 0 0 5 5 5 2 NUC173 domain MMS19_C PF12460.8 GAX24260.1 - 0.00037 19.7 0.0 0.65 9.0 0.0 3.6 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal UME PF08064.13 GAX24260.1 - 0.0027 17.6 0.1 21 5.1 0.0 5.2 4 1 1 5 5 5 0 UME (NUC010) domain CLASP_N PF12348.8 GAX24260.1 - 0.063 12.8 0.4 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 CLASP N terminal DRIM PF07539.12 GAX24260.1 - 0.2 9.9 0.0 5.7 5.1 0.0 2.7 3 0 0 3 3 3 0 Down-regulated in metastasis Vac14_Fab1_bd PF12755.7 GAX24260.1 - 0.21 12.2 2.0 1.1e+02 3.5 0.1 4.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Ribosomal_L41 PF05162.13 GAX24261.1 - 1e-07 31.8 31.7 1.6e-07 31.3 31.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L41 ubiquitin PF00240.23 GAX24261.1 - 0.0003 20.5 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family FapA PF03961.13 GAX24261.1 - 0.053 12.1 0.0 0.056 12.0 0.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rad60-SLD PF11976.8 GAX24261.1 - 0.18 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SBF2 PF12335.8 GAX24262.1 - 2e-05 24.3 1.3 2e-05 24.3 1.3 2.5 2 1 0 2 2 2 1 Myotubularin protein CdvA PF18822.1 GAX24262.1 - 1.6 8.6 7.5 14 5.5 4.4 2.9 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Glyco_transf_25 PF01755.17 GAX24263.1 - 6.1e-16 58.9 0.0 1.2e-15 57.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Pox_P35 PF03213.14 GAX24263.1 - 0.01 15.1 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein bZIP_1 PF00170.21 GAX24264.1 - 1.7e-08 34.4 8.9 1.7e-08 34.4 8.9 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAX24264.1 - 5.8e-05 23.5 7.4 0.00013 22.4 7.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 GAX24264.1 - 0.00013 21.9 12.9 0.00013 21.9 12.9 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Tho2 PF11262.8 GAX24264.1 - 0.076 12.2 5.8 0.11 11.7 5.8 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FapA PF03961.13 GAX24264.1 - 0.24 9.9 2.2 0.3 9.6 2.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 GAX24264.1 - 0.57 8.0 3.0 0.66 7.8 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med21 PF11221.8 GAX24264.1 - 1 9.6 8.1 0.31 11.3 2.2 2.5 1 1 1 2 2 2 0 Subunit 21 of Mediator complex CDC45 PF02724.14 GAX24264.1 - 2.2 6.5 9.1 2.7 6.2 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 GAX24264.1 - 3 7.4 19.9 6.3 6.3 18.2 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein UEV PF05743.13 GAX24265.1 - 3e-26 91.7 0.1 8.4e-26 90.2 0.0 1.8 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 GAX24265.1 - 1.4e-20 73.0 0.3 3.8e-20 71.6 0.3 1.8 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 GAX24265.1 - 9.8e-06 25.3 0.0 2.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Gp-FAR-1 PF05823.12 GAX24265.1 - 0.24 11.8 6.1 0.15 12.4 4.0 1.7 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fibin PF15819.5 GAX24265.1 - 3.3 7.4 9.7 0.21 11.3 0.3 2.4 2 0 0 2 2 2 0 Fin bud initiation factor homologue LMBR1 PF04791.16 GAX24265.1 - 5.2 5.8 5.3 7.3 5.4 5.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Fzo_mitofusin PF04799.13 GAX24265.1 - 7.9 6.0 14.6 5 6.6 12.5 1.8 1 1 0 1 1 1 0 fzo-like conserved region DUF1415 PF07209.12 GAX24266.1 - 0.0066 16.2 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1415) DUF5372 PF17342.2 GAX24266.1 - 0.11 12.9 0.9 23 5.5 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5372) Malic_M PF03949.15 GAX24268.1 - 6.5e-97 323.8 0.0 9.1e-97 323.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAX24268.1 - 5.8e-73 244.6 0.0 9.5e-73 243.9 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain HSF_DNA-bind PF00447.17 GAX24269.1 - 2.6e-18 66.4 0.0 4.6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding baeRF_family2 PF18844.1 GAX24269.1 - 0.084 12.9 0.0 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 DUF1736 PF08409.11 GAX24270.1 - 2.7e-20 72.1 1.1 8e-20 70.6 1.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) Glucos_trans_II PF14264.6 GAX24270.1 - 0.0055 16.1 4.6 0.01 15.2 4.6 1.5 1 1 0 1 1 1 1 Glucosyl transferase GtrII ANAPC3 PF12895.7 GAX24270.1 - 0.0089 16.2 0.1 0.034 14.4 0.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GAX24270.1 - 0.078 12.8 0.4 10 6.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2258 PF10015.9 GAX24271.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Peptidase_C15 PF01470.17 GAX24272.1 - 3.5e-08 33.8 0.0 6.2e-07 29.8 0.0 2.5 1 1 0 1 1 1 1 Pyroglutamyl peptidase RNA_pol_L_2 PF13656.6 GAX24272.1 - 0.1 12.4 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.32 GAX24273.1 - 1.4e-22 79.5 5.0 9.5e-05 23.1 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat FHA PF00498.26 GAX24273.1 - 6e-16 58.5 0.3 1.9e-15 56.9 0.3 1.9 1 0 0 1 1 1 1 FHA domain ANAPC4_WD40 PF12894.7 GAX24273.1 - 2.2e-10 40.7 0.0 0.032 14.5 0.0 5.9 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Yop-YscD_cpl PF16697.5 GAX24273.1 - 6.5e-07 29.6 0.0 2.9e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Nucleoporin_N PF08801.11 GAX24273.1 - 0.0056 15.5 0.0 0.6 8.8 0.0 3.0 3 0 0 3 3 3 1 Nup133 N terminal like HA PF03457.14 GAX24274.1 - 5.5e-138 449.4 27.8 1.9e-21 76.1 0.0 8.3 8 0 0 8 8 8 7 Helicase associated domain DUF4032 PF13224.6 GAX24274.1 - 0.17 11.7 3.4 41 4.0 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4032) Atu4866 PF11512.8 GAX24274.1 - 1.2 9.6 6.8 36 4.8 0.1 5.2 5 0 0 5 5 5 0 Agrobacterium tumefaciens protein Atu4866 PIP5K PF01504.18 GAX24275.1 - 5.2e-74 248.9 0.1 1.5e-73 247.4 0.1 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Phe_ZIP PF08916.11 GAX24275.1 - 0.069 13.9 0.6 0.24 12.1 0.6 1.9 1 0 0 1 1 1 0 Phenylalanine zipper Myb_DNA-binding PF00249.31 GAX24276.1 - 1.4e-13 50.8 0.3 2.7e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX24276.1 - 4.7e-05 23.5 0.3 9e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX24276.1 - 0.0013 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 Myb DNA-binding like RDD PF06271.12 GAX24277.1 - 2e-18 67.0 3.5 3e-18 66.4 3.5 1.3 1 0 0 1 1 1 1 RDD family Mcl1_mid PF12341.8 GAX24278.1 - 6.4e-68 229.3 0.0 1.5e-67 228.1 0.0 1.6 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 GAX24278.1 - 0.00031 21.0 0.1 0.29 11.5 0.0 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX24278.1 - 0.0011 19.8 3.4 1.3 10.0 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 GAX24278.1 - 0.16 12.0 0.0 27 4.8 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Adap_comp_sub PF00928.21 GAX24279.1 - 4.7e-16 59.0 0.0 6.7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF3720 PF12517.8 GAX24279.1 - 1.8 9.6 6.7 0.27 12.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) GRP PF07172.11 GAX24279.1 - 5.1 7.9 18.1 0.088 13.5 3.4 2.4 2 0 0 2 2 2 0 Glycine rich protein family Pkinase_Tyr PF07714.17 GAX24281.1 - 7e-38 130.4 0.0 2.2e-37 128.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GAX24281.1 - 6.3e-33 114.3 0.1 2.5e-32 112.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 GAX24281.1 - 0.12 12.3 0.3 0.3 10.9 0.2 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 GAX24282.1 - 7.1e-16 58.1 16.2 3.5e-11 42.7 5.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily YdjM PF04307.14 GAX24282.1 - 0.033 13.5 0.0 0.12 11.7 0.1 1.8 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Sugar_tr PF00083.24 GAX24282.1 - 0.13 11.1 15.9 0.069 12.0 0.7 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter DUF983 PF06170.12 GAX24282.1 - 8 7.0 8.7 13 6.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF983) APG6 PF04111.12 GAX24283.1 - 5.9e-11 42.6 0.2 5.1e-10 39.6 0.0 2.4 1 1 2 3 3 3 1 Apg6 BARA domain APG6_N PF17675.1 GAX24283.1 - 3.9e-05 24.2 21.2 6e-05 23.6 21.2 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF1664 PF07889.12 GAX24283.1 - 0.0033 17.5 1.7 0.0046 17.0 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 GAX24283.1 - 0.33 11.4 4.4 0.15 12.5 0.6 2.3 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SHE3 PF17078.5 GAX24283.1 - 0.42 10.3 0.1 0.42 10.3 0.1 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Prefoldin_2 PF01920.20 GAX24283.1 - 0.85 9.6 14.6 0.32 11.0 1.8 3.4 1 1 2 3 3 3 0 Prefoldin subunit PEP-utilisers_N PF05524.13 GAX24283.1 - 1.1 9.4 15.4 2.3 8.4 1.4 3.2 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal CCDC-167 PF15188.6 GAX24283.1 - 2.5 8.5 9.1 0.56 10.6 2.9 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4337 PF14235.6 GAX24283.1 - 3.9 7.6 9.5 7.1 6.7 9.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Jnk-SapK_ap_N PF09744.9 GAX24283.1 - 5 7.3 20.0 0.25 11.6 8.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 GAX24283.1 - 8 7.2 10.7 0.68 10.6 0.5 3.2 2 1 0 3 3 3 0 SlyX ThiF PF00899.21 GAX24284.1 - 1e-61 208.4 0.0 1.8e-56 191.2 0.0 3.3 2 1 1 3 3 3 3 ThiF family UBA_e1_thiolCys PF10585.9 GAX24284.1 - 1.1e-44 153.3 0.0 1.6e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GAX24284.1 - 8e-11 42.5 0.0 1.8e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GAX24284.1 - 1.2e-05 25.4 0.3 3.5e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Pyr_redox_2 PF07992.14 GAX24284.1 - 0.099 11.9 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAX24284.1 - 0.14 12.2 0.2 0.58 10.2 0.1 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 GAX24284.1 - 0.17 12.5 0.1 0.69 10.5 0.1 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TLC PF03219.14 GAX24285.1 - 5.3e-182 605.9 1.8 6.4e-182 605.7 1.8 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF3784 PF12650.7 GAX24285.1 - 0.11 12.7 0.2 0.11 12.7 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) PMP1_2 PF08114.11 GAX24285.1 - 0.12 12.2 0.9 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 ATPase proteolipid family DUF4131 PF13567.6 GAX24285.1 - 0.43 10.2 11.3 0.52 9.9 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) GUN4 PF05419.12 GAX24286.1 - 1.4e-44 151.5 0.0 1.8e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 GUN4-like Surp PF01805.20 GAX24287.1 - 1.1e-29 102.2 4.6 8.7e-15 54.5 0.6 3.3 3 0 0 3 3 3 2 Surp module PRP21_like_P PF12230.8 GAX24287.1 - 7.1e-23 81.6 19.4 3.5e-14 53.2 3.7 3.2 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 GAX24287.1 - 0.00025 20.7 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Acyl-thio_N PF12590.8 GAX24287.1 - 0.034 14.7 0.8 0.15 12.6 0.4 2.2 2 0 0 2 2 2 0 Acyl-ATP thioesterase Peptidase_C1 PF00112.23 GAX24288.1 - 1.2e-41 143.2 13.7 1.5e-40 139.6 13.7 2.4 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX24288.1 - 4.8e-12 46.1 2.3 1.1e-11 44.9 2.3 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) ThiF PF00899.21 GAX24289.1 - 7e-29 100.9 0.0 9e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 GAX24289.1 - 0.041 13.2 0.1 0.099 12.0 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAX24289.1 - 0.07 12.4 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 GAX24289.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX24289.1 - 0.16 12.1 0.1 0.36 10.9 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RRM_1 PF00076.22 GAX24291.1 - 8.1e-25 86.4 0.0 4.7e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asparaginase_2 PF01112.18 GAX24291.1 - 0.017 14.2 0.2 0.027 13.5 0.2 1.3 1 0 0 1 1 1 0 Asparaginase RRM_7 PF16367.5 GAX24291.1 - 0.021 14.9 0.0 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif DDHD PF02862.17 GAX24291.1 - 0.059 13.5 0.3 0.062 13.4 0.3 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 GAX24291.1 - 0.47 9.2 5.3 0.59 8.9 5.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Med19 PF10278.9 GAX24291.1 - 1.4 8.9 11.8 2.3 8.1 11.8 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 GAX24291.1 - 1.5 7.5 2.5 1.9 7.2 2.5 1.1 1 0 0 1 1 1 0 Presenilin PRP1_N PF06424.12 GAX24291.1 - 2.7 8.4 13.9 1.4e+02 2.8 0.0 3.1 2 1 1 3 3 3 0 PRP1 splicing factor, N-terminal KIND PF16474.5 GAX24291.1 - 8.1 6.3 9.8 2.2 8.1 1.3 2.7 2 1 1 3 3 3 0 Kinase non-catalytic C-lobe domain HSP90 PF00183.18 GAX24293.1 - 1.5e-156 522.3 7.5 1.9e-156 522.0 7.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAX24293.1 - 4.1e-12 46.6 0.0 8.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX24293.1 - 3.6e-09 36.5 0.0 8.2e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP_bind_1 PF03029.17 GAX24294.1 - 1.1e-67 228.4 0.1 1.4e-67 228.0 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 GAX24294.1 - 1.3e-07 31.6 0.2 0.022 14.7 0.6 3.2 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAX24294.1 - 2.5e-07 31.2 0.0 5.9e-07 30.0 0.0 1.7 2 1 0 2 2 1 1 AAA ATPase domain cobW PF02492.19 GAX24294.1 - 7.7e-06 25.6 0.0 0.082 12.5 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 GAX24294.1 - 1.7e-05 24.9 0.0 0.00026 21.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX24294.1 - 3.2e-05 23.5 0.0 0.00064 19.3 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAX24294.1 - 0.00037 20.0 0.0 0.091 12.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.6 GAX24294.1 - 0.00077 19.7 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAX24294.1 - 0.00084 19.1 0.0 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX24294.1 - 0.0017 17.7 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 GAX24294.1 - 0.0023 17.2 0.0 0.0046 16.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain G-alpha PF00503.20 GAX24294.1 - 0.0027 16.9 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit Ras PF00071.22 GAX24294.1 - 0.0045 16.6 0.0 0.68 9.5 0.0 2.4 2 0 0 2 2 2 1 Ras family ATPase_2 PF01637.18 GAX24294.1 - 0.0068 16.3 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Roc PF08477.13 GAX24294.1 - 0.0074 16.5 0.0 0.08 13.2 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 GAX24294.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 GAX24294.1 - 0.018 15.1 0.3 0.071 13.2 0.0 2.1 2 1 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 GAX24294.1 - 0.022 14.9 0.2 0.061 13.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAX24294.1 - 0.034 13.8 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KAP_NTPase PF07693.14 GAX24294.1 - 0.036 13.3 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain MeaB PF03308.16 GAX24294.1 - 0.04 12.9 0.0 4.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 GAX24294.1 - 0.044 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 GAX24294.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX24294.1 - 0.078 13.5 0.1 0.26 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.9 GAX24294.1 - 0.094 12.5 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAX24294.1 - 0.11 12.0 0.0 0.72 9.3 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Atx10homo_assoc PF09759.9 GAX24295.1 - 4e-22 78.1 0.0 1e-17 64.0 0.0 2.7 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain DUF5345 PF17280.2 GAX24297.1 - 0.18 11.8 0.9 0.43 10.6 0.9 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5345) ShK PF01549.24 GAX24298.1 - 3.9e-12 46.5 9.8 1.1e-05 25.9 2.2 2.1 2 0 0 2 2 2 2 ShK domain-like Crisp PF08562.10 GAX24298.1 - 0.67 10.6 12.9 1 10.0 10.9 1.9 1 1 1 2 2 2 0 Crisp Ank_2 PF12796.7 GAX24300.1 - 0.0022 18.6 0.0 0.0087 16.6 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) F-box-like PF12937.7 GAX24300.1 - 0.029 14.3 0.1 0.079 12.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 GAX24300.1 - 0.086 12.7 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 F-box domain Ank_3 PF13606.6 GAX24300.1 - 0.092 13.4 0.0 32 5.6 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat NMD3 PF04981.13 GAX24301.1 - 1.2e-72 244.3 4.9 2e-72 243.6 4.9 1.3 1 0 0 1 1 1 1 NMD3 family C1_4 PF07975.12 GAX24301.1 - 2.6 8.3 7.2 19 5.6 0.4 3.6 3 0 0 3 3 3 0 TFIIH C1-like domain Ribosomal_L18 PF17135.4 GAX24302.1 - 4.3e-79 264.3 2.9 4.8e-79 264.1 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAX24302.1 - 0.00066 20.3 0.0 0.0012 19.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1737 PF08410.10 GAX24302.1 - 0.09 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Nudc_N PF14050.6 GAX24302.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.7 1 1 0 1 1 1 0 N-terminal conserved domain of Nudc. DUF3833 PF12915.7 GAX24303.1 - 0.018 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) YoeB_toxin PF06769.14 GAX24303.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Mor PF08765.11 GAX24303.1 - 0.16 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Mor transcription activator family RE_MamI PF09567.10 GAX24304.1 - 0.081 12.6 0.1 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 MamI restriction endonuclease Gcd10p PF04189.13 GAX24305.1 - 5.8e-53 180.0 0.0 8.5e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family PhyH PF05721.13 GAX24307.1 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MatP_C PF17414.2 GAX24307.1 - 0.1 12.8 0.4 3.7 7.8 0.1 2.4 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain ATG101 PF07855.12 GAX24308.1 - 3.4e-32 111.6 0.0 4e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 HMG_box PF00505.19 GAX24309.1 - 7.3e-13 48.7 4.0 1.8e-07 31.5 0.5 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX24309.1 - 1.8e-12 47.6 3.7 1.3e-07 32.1 0.6 2.3 2 0 0 2 2 2 2 HMG-box domain MlaC PF05494.12 GAX24309.1 - 0.17 11.6 0.2 0.22 11.3 0.2 1.1 1 0 0 1 1 1 0 MlaC protein YABBY PF04690.13 GAX24309.1 - 0.24 12.0 4.3 0.11 13.1 1.7 1.7 1 1 0 2 2 2 0 YABBY protein Glu_cyclase_2 PF05096.12 GAX24310.1 - 8.8e-57 192.4 0.3 1.2e-56 192.0 0.3 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase SKN1 PF03935.15 GAX24311.1 - 1.1e-71 241.8 11.3 4.8e-60 203.4 8.9 3.9 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAX24311.1 - 1.6e-06 27.7 0.3 0.052 13.0 0.0 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 EGF_2 PF07974.13 GAX24311.1 - 0.00022 21.5 11.8 0.00022 21.5 11.8 2.9 2 1 0 2 2 2 1 EGF-like domain EB PF01683.18 GAX24311.1 - 0.00044 20.5 2.2 0.00044 20.5 2.2 2.4 2 0 0 2 2 2 1 EB module Porin_3 PF01459.22 GAX24312.1 - 2.4e-21 76.4 1.6 2.8e-21 76.2 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic porin DUF4554 PF15091.6 GAX24313.1 - 0.0098 14.8 0.6 0.011 14.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4554) UPF0515 PF15135.6 GAX24313.1 - 0.018 14.4 0.5 0.025 14.0 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Acetyltransf_2 PF00797.17 GAX24315.1 - 3.3e-37 128.6 0.0 4.5e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase NUC153 PF08159.12 GAX24316.1 - 7.2e-07 28.9 3.3 0.00038 20.2 0.1 3.1 3 0 0 3 3 3 2 NUC153 domain RRM_1 PF00076.22 GAX24316.1 - 0.0082 15.9 0.1 0.034 14.0 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1995 PF09353.10 GAX24317.1 - 1.3e-23 84.1 0.0 1.8e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Baculo_PEP_C PF04513.12 GAX24318.1 - 2.3e-06 27.7 10.8 2.2e-05 24.5 9.8 2.3 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CHASE3 PF05227.13 GAX24318.1 - 0.077 12.9 0.4 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 CHASE3 domain NPV_P10 PF05531.12 GAX24318.1 - 0.085 13.3 2.6 3.8 8.0 0.1 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 GAX24318.1 - 0.13 11.6 0.0 0.36 10.1 0.0 1.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1115 PF06544.12 GAX24319.1 - 9.1e-10 38.8 0.1 2.2e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 GAX24319.1 - 0.048 13.9 0.0 0.17 12.2 0.0 1.9 1 1 0 1 1 1 0 RWD domain PilJ PF13675.6 GAX24320.1 - 0.0027 17.7 3.6 0.31 11.1 0.7 2.7 2 0 0 2 2 2 2 Type IV pili methyl-accepting chemotaxis transducer N-term FlxA PF14282.6 GAX24320.1 - 0.0084 16.1 0.3 0.0084 16.1 0.3 3.0 2 1 0 2 2 2 1 FlxA-like protein NPV_P10 PF05531.12 GAX24320.1 - 0.0099 16.3 0.7 0.0099 16.3 0.7 2.6 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein GAIN_A PF18619.1 GAX24320.1 - 0.069 13.4 0.1 0.91 9.8 0.0 2.8 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A ATPase PF06745.13 GAX24320.1 - 0.088 12.1 2.8 0.4 10.0 1.0 2.1 1 1 1 2 2 2 0 KaiC Mlo PF03094.15 GAX24320.1 - 0.3 9.4 1.0 0.54 8.6 1.0 1.3 1 0 0 1 1 1 0 Mlo family DUF948 PF06103.11 GAX24320.1 - 1 9.7 4.1 0.56 10.5 0.5 2.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 GAX24320.1 - 1.8 8.8 12.9 4.1e+02 1.1 15.7 2.6 2 1 0 2 2 2 0 Zinc finger-containing protein TPR_MLP1_2 PF07926.12 GAX24320.1 - 1.9 8.5 14.7 1.6 8.8 4.9 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 GAX24320.1 - 2.6 7.8 10.9 0.33 10.7 1.2 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF745) ABC_tran_CTD PF16326.5 GAX24320.1 - 7.6 6.9 11.3 0.74 10.1 3.4 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain DTW PF03942.15 GAX24321.1 - 1.8e-27 96.4 0.6 3.2e-27 95.5 0.6 1.3 1 0 0 1 1 1 1 DTW domain PSI PF01437.25 GAX24322.1 - 0.0013 19.2 38.2 0.09 13.3 17.4 2.8 1 1 1 2 2 2 2 Plexin repeat PSI_integrin PF17205.3 GAX24322.1 - 0.022 14.5 30.3 0.057 13.2 10.1 2.6 2 0 0 2 2 2 0 Integrin plexin domain LEA_2 PF03168.13 GAX24322.1 - 0.025 15.1 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein AAA_26 PF13500.6 GAX24323.1 - 2.4e-14 53.6 0.0 2.5e-13 50.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX24323.1 - 0.037 14.1 0.0 0.099 12.7 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PAP2 PF01569.21 GAX24324.1 - 7.7e-26 90.5 0.4 1.5e-25 89.6 0.4 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 GAX24324.1 - 0.0032 17.2 3.0 0.076 12.7 0.6 2.5 2 1 0 2 2 2 2 PAP2 superfamily Fer4_13 PF13370.6 GAX24325.1 - 1.3e-09 38.5 3.8 1.3e-09 38.5 3.8 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 GAX24325.1 - 6e-08 33.3 3.3 4.2e-07 30.6 3.3 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_10 PF13237.6 GAX24325.1 - 0.00028 20.9 1.2 0.00072 19.6 1.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAX24325.1 - 0.0035 17.3 0.8 0.0035 17.3 0.8 1.9 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4 PF00037.27 GAX24325.1 - 0.0045 16.7 1.3 0.0045 16.7 1.3 2.1 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 GAX24325.1 - 0.005 16.9 3.7 0.015 15.4 3.7 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAX24325.1 - 0.0065 16.5 0.5 0.017 15.2 0.5 1.8 1 0 0 1 1 1 1 4Fe-4S binding domain NARG2_C PF10505.9 GAX24325.1 - 0.022 14.3 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Fer4_9 PF13187.6 GAX24325.1 - 0.043 14.0 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 GAX24325.1 - 0.048 14.3 3.2 0.46 11.1 3.3 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_19 PF06902.11 GAX24325.1 - 0.19 11.8 0.7 0.52 10.4 0.7 1.7 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster ORC5_C PF14630.6 GAX24326.1 - 6.6e-32 111.2 0.0 2e-30 106.3 0.1 2.4 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 GAX24326.1 - 1e-07 32.5 0.0 2.2e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX24326.1 - 2.2e-06 28.0 0.0 0.00079 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAX24326.1 - 0.0064 16.9 0.0 0.36 11.2 0.0 3.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 GAX24326.1 - 0.013 15.9 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX24326.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 GAX24326.1 - 0.053 13.4 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SLX9 PF15341.6 GAX24326.1 - 0.063 13.7 1.3 15 5.9 0.4 2.9 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 NTPase_1 PF03266.15 GAX24326.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 GAX24326.1 - 0.096 12.6 0.0 0.92 9.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Proteasome PF00227.26 GAX24329.1 - 5e-22 78.3 0.0 7.2e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX24329.1 - 2.3e-08 33.5 0.0 7.1e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Tcp11 PF05794.13 GAX24329.1 - 0.1 11.7 1.0 0.14 11.2 1.0 1.1 1 0 0 1 1 1 0 T-complex protein 11 ABC1 PF03109.16 GAX24330.1 - 7e-23 81.1 0.0 2.5e-22 79.2 0.0 2.0 1 1 0 1 1 1 1 ABC1 family APH PF01636.23 GAX24330.1 - 0.00052 20.0 0.1 0.007 16.3 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX24330.1 - 0.018 14.7 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Acyl_transf_3 PF01757.22 GAX24331.1 - 8.8e-22 77.6 26.5 8.8e-22 77.6 26.5 2.8 2 1 1 3 3 3 2 Acyltransferase family Proteasome PF00227.26 GAX24332.1 - 2.8e-49 167.2 0.3 3.6e-49 166.8 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Bestrophin PF01062.21 GAX24333.1 - 2.3e-21 76.4 0.1 3.2e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Response_reg PF00072.24 GAX24334.1 - 1.7e-25 89.3 0.0 4.6e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 GAX24334.1 - 9.9e-05 21.8 0.1 0.00023 20.6 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 GAX24334.1 - 0.0067 16.2 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Popeye PF04831.13 GAX24335.1 - 1.4e-06 28.6 0.1 2e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 GAX24335.1 - 0.0049 16.9 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1241 PF06840.11 GAX24335.1 - 0.035 13.8 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) COG6 PF06419.11 GAX24336.1 - 0.1 10.8 0.1 0.15 10.2 0.1 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 SelR PF01641.18 GAX24337.1 - 0.0077 16.3 0.2 0.026 14.6 0.2 2.0 1 1 0 1 1 1 1 SelR domain FCP1_C PF09309.10 GAX24337.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 FCP1, C-terminal GILT PF03227.16 GAX24339.1 - 5.6e-21 74.8 0.3 1e-20 74.0 0.3 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) GILT PF03227.16 GAX24340.1 - 1.4e-20 73.5 0.1 2.8e-20 72.6 0.0 1.5 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) GNAT_like PF18407.1 GAX24340.1 - 0.062 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain Hemerythrin PF01814.23 GAX24341.1 - 1.6e-06 28.7 0.3 5.7e-05 23.7 0.3 2.8 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain AceK PF06315.11 GAX24341.1 - 0.00047 18.8 0.3 0.00062 18.4 0.3 1.1 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) PNMA PF14893.6 GAX24341.1 - 0.18 11.2 4.2 0.095 12.1 1.1 1.8 1 1 1 2 2 2 0 PNMA EST1 PF10374.9 GAX24341.1 - 0.21 12.2 6.8 0.19 12.4 4.7 2.0 1 1 1 2 2 2 0 Telomerase activating protein Est1 TBCA PF02970.16 GAX24341.1 - 0.53 10.7 9.6 0.035 14.4 3.6 2.1 2 0 0 2 2 2 0 Tubulin binding cofactor A Remorin_C PF03763.13 GAX24342.1 - 0.053 13.4 0.7 0.053 13.4 0.7 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region HSBP1 PF06825.12 GAX24342.1 - 1.7 8.6 6.5 4.2 7.3 6.2 1.8 1 1 1 2 2 2 0 Heat shock factor binding protein 1 PMBR PF09373.10 GAX24345.1 - 0.0097 16.0 0.0 0.032 14.4 0.0 1.9 1 0 0 1 1 1 1 Pseudomurein-binding repeat TPT PF03151.16 GAX24346.1 - 2.5e-30 105.8 8.5 3.2e-30 105.5 8.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family His_Phos_1 PF00300.22 GAX24347.1 - 1.2e-08 34.9 3.9 7e-08 32.4 2.7 2.6 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DAGAT PF03982.13 GAX24348.1 - 6.4e-30 104.1 0.1 8.8e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase GerD PF17898.1 GAX24349.1 - 3.5e-07 30.2 28.3 0.00014 21.8 6.4 2.4 1 1 0 2 2 2 2 Spore germination GerD central core domain Ins_allergen_rp PF06757.13 GAX24349.1 - 0.003 17.5 5.8 1.2 9.1 0.6 3.4 3 0 0 3 3 3 2 Insect allergen related repeat, nitrile-specifier detoxification Abhydrolase_3 PF07859.13 GAX24349.1 - 0.023 14.6 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold STI1 PF17830.1 GAX24349.1 - 0.026 14.4 30.8 0.013 15.4 7.9 4.2 2 2 1 3 3 3 0 STI1 domain RPN13_C PF16550.5 GAX24349.1 - 0.031 14.4 10.0 0.29 11.3 0.9 2.5 1 1 0 2 2 2 0 UCH-binding domain DevR PF01905.16 GAX24349.1 - 0.045 12.8 2.7 0.074 12.1 2.7 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Abhydrolase_6 PF12697.7 GAX24349.1 - 0.05 14.2 3.2 0.12 12.9 2.7 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 GAX24349.1 - 0.051 12.5 1.1 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme PGAP1 PF07819.13 GAX24349.1 - 0.075 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 GAX24349.1 - 0.082 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) DUF1310 PF07006.11 GAX24349.1 - 0.25 11.3 3.6 0.46 10.5 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) Nif11 PF07862.11 GAX24349.1 - 0.28 11.5 8.1 4.8 7.6 0.1 4.0 2 2 2 4 4 4 0 Nif11 domain ParE-like_toxin PF15781.5 GAX24349.1 - 1.5 8.8 4.4 22 5.1 0.2 2.5 2 0 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system DnaJ_C PF01556.18 GAX24350.1 - 8.4e-35 120.0 0.0 1.2e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX24350.1 - 6.4e-25 87.1 2.9 1.1e-24 86.3 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAX24350.1 - 0.00012 22.4 2.4 0.00026 21.3 2.4 1.5 1 0 0 1 1 1 1 DnaJ central domain TB PF00683.17 GAX24350.1 - 0.02 14.6 0.5 0.047 13.4 0.5 1.6 1 0 0 1 1 1 0 TB domain Radical_SAM PF04055.21 GAX24351.1 - 4.9e-16 59.6 0.0 8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 GAX24351.1 - 2.3e-10 40.8 0.2 6.5e-10 39.4 0.2 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family RRS1 PF04939.12 GAX24352.1 - 2.5e-39 134.7 7.3 3.2e-38 131.1 4.7 2.9 1 1 1 2 2 2 2 Ribosome biogenesis regulatory protein (RRS1) Cid2 PF09774.9 GAX24352.1 - 0.045 14.2 1.2 0.045 14.2 1.2 2.4 2 0 0 2 2 2 0 Caffeine-induced death protein 2 Pkinase PF00069.25 GAX24353.1 - 5.8e-35 120.9 0.0 6.9e-26 91.2 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24353.1 - 1.8e-19 70.0 0.1 1.7e-18 66.9 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase MFS_1 PF07690.16 GAX24356.1 - 3.7e-13 49.1 26.7 3.7e-13 49.1 26.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1385 PF07136.11 GAX24356.1 - 0.14 11.5 2.5 0.24 10.7 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1385) EMP24_GP25L PF01105.24 GAX24357.1 - 1.9e-15 57.3 0.9 2.6e-15 56.8 0.9 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sec20 PF03908.13 GAX24357.1 - 0.088 12.7 0.9 0.16 11.9 0.9 1.4 1 0 0 1 1 1 0 Sec20 Cytochrom_C552 PF02335.15 GAX24357.1 - 0.54 9.1 5.2 0.87 8.4 1.8 2.0 2 0 0 2 2 2 0 Cytochrome c552 Allantoicase PF03561.15 GAX24358.1 - 4.5e-82 273.1 0.0 2.1e-41 141.3 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat JAB PF01398.21 GAX24359.1 - 4e-07 30.0 0.1 1.1e-06 28.6 0.1 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA-synt_2 PF00152.20 GAX24360.1 - 7e-80 268.4 0.1 9.1e-80 268.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX24360.1 - 6.2e-14 51.8 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX24360.1 - 3.3e-07 30.1 0.0 0.0024 17.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) YbaB_DNA_bd PF02575.16 GAX24361.1 - 3.3e-08 33.6 1.0 2.6e-07 30.8 1.0 2.0 1 1 0 1 1 1 1 YbaB/EbfC DNA-binding family Ycf1 PF05758.12 GAX24361.1 - 0.08 10.8 0.0 0.1 10.4 0.0 1.0 1 0 0 1 1 1 0 Ycf1 MA3 PF02847.17 GAX24362.1 - 5e-19 68.4 1.5 5e-19 68.4 1.5 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 GAX24362.1 - 5.3e-13 49.1 1.0 2.7e-12 46.8 0.0 2.5 2 2 0 2 2 2 1 MIF4G domain HSP20 PF00011.21 GAX24363.1 - 5.4e-17 61.8 0.4 7.4e-17 61.4 0.4 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAX24363.1 - 0.03 13.9 0.4 0.06 12.9 0.4 1.6 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Rep_fac_C PF08542.11 GAX24364.1 - 2.8e-23 82.1 0.0 1.6e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 GAX24364.1 - 9.9e-16 58.4 0.0 1.7e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAX24364.1 - 7.2e-11 42.1 0.1 4.9e-08 32.9 0.3 2.8 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 GAX24364.1 - 2.4e-07 31.3 0.1 0.00013 22.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX24364.1 - 8.1e-07 29.4 0.2 0.0015 18.8 0.1 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 GAX24364.1 - 1.2e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 GAX24364.1 - 1.7e-06 28.1 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAX24364.1 - 2.2e-05 23.9 0.0 0.00041 19.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAX24364.1 - 6.2e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAX24364.1 - 8.2e-05 22.6 0.0 0.00021 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAX24364.1 - 8.6e-05 22.4 0.0 0.00028 20.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 GAX24364.1 - 0.00012 22.4 0.0 0.0004 20.7 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 GAX24364.1 - 0.00021 21.1 0.1 0.0004 20.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 GAX24364.1 - 0.00034 20.4 0.0 0.0011 18.8 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 GAX24364.1 - 0.00042 20.1 0.0 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 GAX24364.1 - 0.00048 20.2 0.0 1.6 8.7 0.0 2.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 GAX24364.1 - 0.00049 20.6 0.0 0.00081 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX24364.1 - 0.00051 20.2 0.2 0.0025 18.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAX24364.1 - 0.0011 19.4 0.0 0.0033 17.8 0.0 2.0 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 GAX24364.1 - 0.0022 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein KTI12 PF08433.10 GAX24364.1 - 0.0024 17.4 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.6 GAX24364.1 - 0.0024 18.2 0.4 0.029 14.7 0.1 2.3 2 1 1 3 3 2 1 AAA domain NTPase_1 PF03266.15 GAX24364.1 - 0.0027 17.6 0.1 0.052 13.4 0.0 2.5 2 1 0 3 3 2 1 NTPase TniB PF05621.11 GAX24364.1 - 0.0034 16.8 0.0 0.16 11.3 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein MeaB PF03308.16 GAX24364.1 - 0.0034 16.4 0.0 0.0065 15.5 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 GAX24364.1 - 0.0037 17.1 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAX24364.1 - 0.0038 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region MCM PF00493.23 GAX24364.1 - 0.0048 16.0 0.0 0.0082 15.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_24 PF13479.6 GAX24364.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAX24364.1 - 0.0079 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 GAX24364.1 - 0.011 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX24364.1 - 0.03 13.7 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DEAD PF00270.29 GAX24364.1 - 0.032 14.0 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.22 GAX24364.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 GAX24364.1 - 0.074 12.6 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAX24364.1 - 0.076 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 GAX24364.1 - 0.082 12.8 0.1 0.67 9.9 0.1 2.1 1 1 0 1 1 1 0 NACHT domain Psm4 PF17063.5 GAX24364.1 - 3 8.7 5.3 1.2 9.9 0.1 2.9 3 0 0 3 3 2 0 Phenol-soluble modulin alpha 4 peptide Gpi1 PF05024.15 GAX24365.1 - 0.0014 18.7 2.5 0.0014 18.7 2.5 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Cyclin_N PF00134.23 GAX24366.1 - 2.3e-16 59.7 0.0 3.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX24366.1 - 0.0021 18.1 0.1 0.0088 16.1 0.1 2.0 3 0 0 3 3 3 1 Cyclin, C-terminal domain MMR_HSR1 PF01926.23 GAX24367.1 - 3.3e-09 36.8 0.0 1.7e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX24367.1 - 6.3e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 GAX24367.1 - 0.004 16.7 0.0 0.34 10.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAX24367.1 - 0.0088 16.1 1.1 0.021 14.9 0.0 2.2 3 0 0 3 3 3 1 Dynamin family FeoB_N PF02421.18 GAX24367.1 - 0.014 14.9 0.0 0.37 10.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 GAX24367.1 - 0.017 15.3 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MT0933_antitox PF14013.6 GAX24367.1 - 0.11 12.9 2.1 6.2 7.2 0.1 3.1 3 0 0 3 3 3 0 MT0933-like antitoxin protein CAF-1_p60_C PF15512.6 GAX24368.1 - 0.0062 17.0 2.5 0.1 13.1 2.5 2.4 1 1 0 1 1 1 1 Chromatin assembly factor complex 1 subunit p60, C-terminal MatE PF01554.18 GAX24369.1 - 3.3e-33 114.6 29.3 6.3e-22 77.9 9.3 2.9 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAX24369.1 - 4.4e-06 26.8 9.9 4.4e-06 26.8 9.9 3.2 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain SGL PF08450.12 GAX24370.1 - 4.4e-43 147.6 0.0 5.4e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 GAX24370.1 - 0.012 15.6 0.0 0.17 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) CRAL_TRIO PF00650.20 GAX24371.1 - 1.4e-13 50.9 0.0 3.4e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain Organ_specific PF10950.8 GAX24371.1 - 0.05 14.3 0.0 0.13 13.0 0.0 1.7 1 1 0 1 1 1 0 Organ specific protein CRAL_TRIO_2 PF13716.6 GAX24371.1 - 0.087 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAX24372.1 - 7.1e-13 48.6 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX24372.1 - 2.5e-06 27.7 0.0 4.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CCM2_C PF16545.5 GAX24372.1 - 0.013 16.0 0.1 0.034 14.7 0.1 1.7 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology APP_N PF02177.16 GAX24372.1 - 0.028 14.8 0.3 0.053 13.9 0.3 1.4 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Phos_pyr_kin PF08543.12 GAX24372.1 - 0.06 12.7 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase PAS PF00989.25 GAX24374.1 - 1e-66 222.0 0.2 1.3e-22 79.9 0.0 5.3 5 0 0 5 5 5 5 PAS fold PAS_9 PF13426.7 GAX24374.1 - 1.1e-36 125.3 3.2 3e-09 37.1 0.3 5.3 5 0 0 5 5 5 4 PAS domain PAS_4 PF08448.10 GAX24374.1 - 3e-35 120.8 0.0 6.5e-10 39.2 0.0 5.3 5 0 0 5 5 5 5 PAS fold HATPase_c PF02518.26 GAX24374.1 - 6.3e-26 91.1 0.2 3.3e-25 88.8 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 GAX24374.1 - 3.1e-17 62.1 0.0 0.00029 20.8 0.0 5.5 5 0 0 5 5 5 2 PAS domain PAS_3 PF08447.12 GAX24374.1 - 3.1e-16 59.4 0.0 7.3e-07 29.4 0.0 4.4 5 0 0 5 5 5 3 PAS fold Response_reg PF00072.24 GAX24374.1 - 4.5e-10 39.7 0.8 1.3e-09 38.2 0.2 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAX24374.1 - 4.7e-08 33.0 0.0 2.4e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 GAX24374.1 - 0.001 19.0 0.0 0.0031 17.4 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_10 PF13596.6 GAX24374.1 - 0.0057 17.2 0.6 2 9.0 0.0 3.7 4 1 0 4 4 4 1 PAS domain CRAL_TRIO PF00650.20 GAX24375.1 - 3.5e-21 75.6 0.0 5.4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX24375.1 - 4.3e-05 23.7 0.0 0.00012 22.2 0.0 1.7 1 1 1 2 2 2 1 Divergent CRAL/TRIO domain UvrD-helicase PF00580.21 GAX24376.1 - 3.9e-61 207.3 0.0 4.5e-60 203.8 0.0 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 GAX24376.1 - 1.3e-54 185.9 0.0 5.5e-54 183.9 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 GAX24376.1 - 4.5e-29 101.7 0.0 1.2e-28 100.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 GAX24376.1 - 1.5e-08 34.3 0.1 6.3e-08 32.3 0.1 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 GAX24376.1 - 9.9e-08 31.9 0.0 0.00034 20.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 GAX24376.1 - 1.8e-06 27.9 0.0 0.018 14.8 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 GAX24376.1 - 3.9e-05 23.4 0.1 0.1 12.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 GAX24376.1 - 0.041 13.7 0.0 0.041 13.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain Pro_isomerase PF00160.21 GAX24377.1 - 2.9e-47 160.9 0.1 4.7e-47 160.2 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 GAX24377.1 - 1.6e-31 108.5 0.0 4.2e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 GAX24377.1 - 1.8e-08 33.8 4.5 0.065 13.4 0.5 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24377.1 - 2.3e-07 30.3 2.0 0.011 15.6 0.4 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX24377.1 - 9.2e-07 28.9 0.2 1.5e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX24377.1 - 7.7e-05 22.9 0.5 1.4 9.3 0.0 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX24377.1 - 0.0067 16.6 0.2 0.0067 16.6 0.2 3.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX24377.1 - 0.0099 16.5 0.5 4.4 8.0 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX24377.1 - 0.012 15.2 0.3 11 5.8 0.0 3.3 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 GAX24377.1 - 0.021 15.5 4.1 5.7 7.8 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX24377.1 - 0.047 14.2 2.9 5.5 7.6 0.0 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat Ntox33 PF15533.6 GAX24377.1 - 0.083 13.4 0.9 4.8 7.7 0.2 2.6 2 0 0 2 2 2 0 Bacterial toxin 33 AstA PF04958.12 GAX24379.1 - 0.026 13.1 0.0 0.03 12.9 0.0 1.0 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit SKI PF01202.22 GAX24381.1 - 1.4e-44 152.0 0.0 1.7e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 GAX24381.1 - 3.7e-06 27.2 0.0 2.1e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX24381.1 - 6e-05 23.6 0.0 0.00016 22.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAX24381.1 - 0.00057 20.3 0.3 0.012 16.0 0.1 2.6 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 GAX24381.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA PF00004.29 GAX24381.1 - 0.005 17.3 0.0 0.0067 16.9 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 GAX24381.1 - 0.0058 16.5 0.2 0.63 9.9 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase CTP_transf_3 PF02348.19 GAX24381.1 - 0.014 15.4 0.0 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 Cytidylyltransferase Thymidylate_kin PF02223.17 GAX24381.1 - 0.043 13.5 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.6 GAX24381.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain HMG_box PF00505.19 GAX24382.1 - 1.1e-15 57.8 16.6 8.9e-08 32.4 8.0 4.2 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX24382.1 - 3.7e-15 56.3 12.1 1.9e-07 31.5 4.4 3.6 2 1 1 3 3 3 2 HMG-box domain HMG_box_5 PF14887.6 GAX24382.1 - 0.014 15.4 3.1 0.018 15.0 1.0 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 YABBY PF04690.13 GAX24382.1 - 1.6 9.3 15.5 2.2 8.8 3.0 3.0 1 1 1 2 2 2 0 YABBY protein Abhydrolase_2 PF02230.16 GAX24383.1 - 1.2e-36 126.5 0.0 1.5e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAX24383.1 - 5.2e-06 27.2 0.1 6.6e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAX24383.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 GAX24383.1 - 0.00047 19.8 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX24383.1 - 0.00054 19.5 0.0 0.42 10.0 0.0 2.1 1 1 0 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.9 GAX24383.1 - 0.00057 19.5 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 GAX24383.1 - 0.0014 18.3 0.0 0.0028 17.3 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 GAX24383.1 - 0.0025 17.7 0.0 0.0067 16.3 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 GAX24383.1 - 0.0034 17.0 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 GAX24383.1 - 0.0057 16.3 0.1 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 GAX24383.1 - 0.0083 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Cutinase PF01083.22 GAX24383.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase Hydrolase_4 PF12146.8 GAX24383.1 - 0.028 13.7 0.0 0.083 12.1 0.0 1.8 2 1 0 2 2 2 0 Serine aminopeptidase, S33 FSH1 PF03959.13 GAX24383.1 - 0.03 14.0 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 GAX24383.1 - 0.085 11.4 0.0 0.26 9.7 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II zf-RING_11 PF17123.5 GAX24384.1 - 2e-11 43.4 2.7 1.3e-10 40.8 2.6 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 GAX24384.1 - 2.2e-11 43.9 8.4 3.5e-11 43.2 8.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX24384.1 - 5.8e-08 32.5 6.7 9.2e-08 31.8 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX24384.1 - 1.3e-06 28.2 5.6 1.3e-06 28.2 5.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX24384.1 - 5.8e-06 26.5 10.2 1.3e-05 25.4 10.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAX24384.1 - 0.00016 21.6 3.0 0.00026 21.0 3.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAX24384.1 - 0.00017 21.5 5.2 0.00027 20.8 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX24384.1 - 0.00037 20.4 2.0 0.00037 20.4 2.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 GAX24384.1 - 0.00073 19.1 6.3 0.0013 18.3 6.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 GAX24384.1 - 0.38 10.7 8.9 0.63 9.9 8.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX24384.1 - 0.56 10.4 7.2 4.3 7.6 7.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 GAX24384.1 - 0.57 10.3 6.5 1.1 9.5 6.5 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 GAX24384.1 - 0.91 9.4 6.6 1.6 8.6 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 GAX24384.1 - 6.4 6.8 8.3 12 5.9 8.3 1.5 1 0 0 1 1 1 0 PHD-finger Polysacc_deac_1 PF01522.21 GAX24385.1 - 2.5e-13 50.0 0.0 3.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase TC1 PF15063.6 GAX24385.1 - 0.088 12.7 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Thyroid cancer protein 1 PI3_PI4_kinase PF00454.27 GAX24386.1 - 2.1e-45 155.5 0.0 1.2e-42 146.5 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAX24386.1 - 2.9e-44 150.7 1.2 1e-43 148.9 0.7 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 GAX24386.1 - 4.8e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 RRF PF01765.19 GAX24388.1 - 7.1e-60 201.6 5.8 1.5e-59 200.6 4.5 1.8 1 1 1 2 2 2 1 Ribosome recycling factor ParA PF10609.9 GAX24389.1 - 4e-65 219.7 0.0 5.8e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAX24389.1 - 3.9e-10 39.9 0.0 6e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX24389.1 - 6.3e-09 36.0 0.1 3e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 GAX24389.1 - 3.2e-06 26.6 0.0 5.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 GAX24389.1 - 4.7e-05 22.7 0.3 0.0089 15.2 0.1 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase VirC1 PF07015.11 GAX24389.1 - 0.0028 17.0 0.0 0.0056 16.0 0.0 1.5 1 0 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.18 GAX24389.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 GAX24389.1 - 0.025 14.4 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 GAX24389.1 - 0.031 13.3 1.0 0.035 13.1 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 GAX24389.1 - 0.038 13.5 0.3 0.32 10.4 0.1 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GAX24389.1 - 0.12 12.0 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain zf-CCCH PF00642.24 GAX24390.1 - 1.3e-28 98.3 21.8 7.4e-10 38.5 1.8 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAX24390.1 - 2e-15 56.2 37.1 1.2e-05 25.1 5.6 3.3 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 GAX24390.1 - 2.2e-09 36.9 29.9 0.0027 17.5 5.0 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 GAX24390.1 - 1.6e-07 32.0 7.6 0.013 16.2 0.1 3.4 3 0 0 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 GAX24390.1 - 1.8e-06 28.2 25.4 0.0044 17.5 2.1 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 GAX24390.1 - 1.6 9.0 9.0 22 5.3 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger containing family SSB PF00436.25 GAX24391.1 - 6.6e-25 87.2 0.0 9.2e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DTW PF03942.15 GAX24392.1 - 8.5e-13 48.5 0.0 1.3e-12 47.9 0.0 1.4 1 1 0 1 1 1 1 DTW domain Atg14 PF10186.9 GAX24392.1 - 0.27 10.3 1.1 0.37 9.8 1.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAGH_C PF16123.5 GAX24393.1 - 6.6e-25 87.4 0.0 1.1e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAX24393.1 - 6.3e-15 55.7 3.5 1.1e-12 48.3 3.5 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAX24393.1 - 0.035 13.6 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ADH_zinc_N PF00107.26 GAX24394.1 - 7.8e-24 84.1 0.1 1.3e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX24394.1 - 2.3e-18 66.1 2.5 4.7e-18 65.1 2.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 GAX24394.1 - 0.0024 17.2 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAX24394.1 - 0.0035 16.7 0.9 0.0057 16.0 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAX24394.1 - 0.0058 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 GAX24394.1 - 0.0075 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 GAX24394.1 - 0.048 14.3 0.2 0.091 13.3 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF382 PF04037.13 GAX24395.1 - 3.1e-52 176.0 0.1 3.1e-52 176.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 GAX24395.1 - 3.8e-17 61.9 4.7 7.5e-17 60.9 4.7 1.5 1 0 0 1 1 1 1 PSP Phage_Gp23 PF10669.9 GAX24395.1 - 0.098 13.0 0.3 0.098 13.0 0.3 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) TMEM171 PF15471.6 GAX24395.1 - 0.22 10.5 1.5 0.36 9.8 1.5 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 RPN2_C PF18004.1 GAX24395.1 - 6.3 6.7 11.9 2.5 8.0 3.1 2.8 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_pol PF00940.19 GAX24396.1 - 1.8e-149 498.1 0.0 5e-149 496.6 0.0 1.8 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 GAX24396.1 - 1.5e-59 202.1 0.9 2.3e-59 201.5 0.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Dynein_light PF01221.18 GAX24397.1 - 3.7e-39 132.9 1.5 4.1e-39 132.8 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF1995 PF09353.10 GAX24398.1 - 3.4e-16 59.9 0.0 5.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF1848 PF08902.11 GAX24398.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) RRM_1 PF00076.22 GAX24399.1 - 3.4e-08 33.2 0.0 8.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 GAX24399.1 - 5.2e-05 23.7 0.0 0.00058 20.3 0.0 2.6 1 1 0 1 1 1 1 SET domain TauD PF02668.16 GAX24400.1 - 1.6e-26 93.7 0.1 4.7e-26 92.2 0.1 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1281 PF06924.11 GAX24400.1 - 0.019 14.5 0.1 5.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) Chloroa_b-bind PF00504.21 GAX24401.1 - 3.2e-31 109.0 0.0 5.9e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HEAT_2 PF13646.6 GAX24402.1 - 1.1e-07 32.1 2.3 0.23 11.9 0.3 4.4 3 0 0 3 3 3 3 HEAT repeats IFRD PF05004.13 GAX24402.1 - 0.06 12.4 12.1 3.2 6.8 0.2 4.9 4 1 0 5 5 5 0 Interferon-related developmental regulator (IFRD) TFIIB PF00382.19 GAX24402.1 - 0.26 11.4 2.4 7.2 6.7 0.0 3.1 2 0 0 2 2 2 0 Transcription factor TFIIB repeat HEAT PF02985.22 GAX24402.1 - 0.43 11.0 14.0 17 6.0 0.1 7.0 7 1 1 8 8 8 0 HEAT repeat CLASP_N PF12348.8 GAX24402.1 - 1.4 8.5 7.3 4.6 6.7 0.0 4.3 5 0 0 5 5 5 0 CLASP N terminal PT PF04886.12 GAX24403.1 - 0.058 13.0 26.5 0.21 11.2 12.9 3.6 1 1 1 2 2 2 0 PT repeat Oxygenase-NA PF09859.9 GAX24405.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA AbfS_sensor PF18225.1 GAX24405.1 - 0.6 10.1 3.4 0.99 9.4 0.1 2.8 3 0 0 3 3 3 0 Sensor histidine kinase (AbfS) sensor domain Exonuc_VII_L PF02601.15 GAX24406.1 - 0.068 12.7 0.3 0.1 12.1 0.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MtN3_slv PF03083.16 GAX24407.1 - 1.7e-31 108.1 7.8 3.5e-16 59.0 0.7 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange V-SNARE_C PF12352.8 GAX24408.1 - 2.5e-07 30.9 0.1 2.5e-07 30.9 0.1 3.1 4 1 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.21 GAX24408.1 - 0.0047 16.7 0.1 0.0047 16.7 0.1 2.5 3 0 0 3 3 3 1 Synaptobrevin Fascin PF06268.13 GAX24408.1 - 0.0048 17.1 0.1 0.012 15.9 0.1 1.7 1 0 0 1 1 1 1 Fascin domain EzrA PF06160.12 GAX24408.1 - 0.23 9.6 8.4 0.16 10.1 5.4 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Pup_ligase PF03136.15 GAX24408.1 - 0.57 9.1 7.2 0.36 9.8 0.1 2.6 2 1 1 3 3 3 0 Pup-ligase protein Sec34 PF04136.15 GAX24408.1 - 5.9 6.8 13.9 0.39 10.6 2.4 2.8 3 0 0 3 3 3 0 Sec34-like family DUF1325 PF07039.11 GAX24409.1 - 5.5e-15 55.6 0.0 1.5e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 SGF29 tudor-like domain PPR_2 PF13041.6 GAX24410.1 - 1.8e-32 111.3 15.6 0.00016 21.8 0.1 11.6 6 3 6 12 12 12 9 PPR repeat family PPR_1 PF12854.7 GAX24410.1 - 1.1e-26 92.2 1.6 0.13 12.0 0.0 13.6 15 1 0 15 15 15 9 PPR repeat PPR_3 PF13812.6 GAX24410.1 - 1.5e-22 79.4 0.6 0.13 12.3 0.0 10.6 7 3 4 11 11 11 8 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX24410.1 - 2.7e-08 33.5 17.7 0.00062 19.2 0.2 5.4 1 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX24410.1 - 4.2e-06 26.6 38.3 2.5 8.5 0.0 14.2 16 2 0 16 16 16 2 PPR repeat Annexin_like PF18411.1 GAX24410.1 - 0.049 13.9 1.4 1.7 9.0 0.2 3.5 2 1 1 3 3 3 0 Annexin-like domain DUF503 PF04456.12 GAX24410.1 - 0.1 12.4 0.1 0.4 10.6 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF503) WD40 PF00400.32 GAX24411.1 - 2.6e-21 75.5 15.9 7.3e-05 23.5 0.0 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX24411.1 - 1.8e-07 31.3 0.4 0.19 12.1 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX24411.1 - 0.036 13.4 0.0 0.71 9.1 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain DUF4149 PF13664.6 GAX24412.1 - 1.4e-27 96.0 4.3 1.4e-27 96.0 4.3 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 GAX24412.1 - 0.0096 16.2 5.6 0.25 11.6 5.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) AzlD PF05437.12 GAX24412.1 - 0.015 15.4 0.8 0.015 15.4 0.8 2.8 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) RNA_POL_M_15KD PF02150.16 GAX24413.1 - 4.8e-09 35.9 0.9 4.8e-09 35.9 0.9 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 GAX24413.1 - 4.6e-06 26.4 3.7 4.6e-06 26.4 3.7 2.2 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) DUF3268 PF11672.8 GAX24413.1 - 0.52 10.7 4.4 1.3 9.3 1.2 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain PTPRCAP PF15713.5 GAX24413.1 - 1.3 9.3 7.8 2.1 8.6 7.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 GAX24413.1 - 4.8 5.2 12.2 5.4 5.0 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 GAX24413.1 - 7 7.1 12.4 11 6.5 12.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1731 PF08338.11 GAX24414.1 - 1.1e-16 60.3 0.1 2.3e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 GAX24414.1 - 4.7e-07 29.5 0.0 1.7e-05 24.4 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX24414.1 - 0.13 11.4 0.1 0.56 9.2 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain CTP_transf_1 PF01148.20 GAX24415.1 - 1.2e-61 208.8 13.8 1.9e-61 208.2 13.8 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Aldedh PF00171.22 GAX24416.1 - 1.7e-43 148.8 0.0 2.1e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2470 PF10615.9 GAX24418.1 - 2.6e-07 31.1 0.0 4.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 GAX24418.1 - 0.00011 22.5 0.4 0.00028 21.2 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF4010 PF13194.6 GAX24418.1 - 0.0044 16.7 0.6 0.0064 16.2 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) MFS_1 PF07690.16 GAX24419.1 - 6e-22 78.0 31.1 4.1e-16 58.8 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAX24419.1 - 0.0012 17.8 15.1 0.04 12.8 15.1 2.7 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAX24420.1 - 9.3e-19 67.6 39.0 3.2e-12 46.1 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAX24420.1 - 1.1e-06 27.8 10.5 2.1e-06 26.9 10.5 1.4 1 1 0 1 1 1 1 MFS_1 like family Sod_Fe_C PF02777.18 GAX24421.1 - 2.4e-34 117.6 0.0 3.9e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAX24421.1 - 1.5e-32 111.9 0.2 2.5e-32 111.2 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Phytochelatin PF05023.14 GAX24422.1 - 9.3e-84 279.9 0.0 1.2e-83 279.5 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase NAD_binding_10 PF13460.6 GAX24423.1 - 1e-26 94.0 0.0 1.5e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 GAX24423.1 - 3.2e-05 24.0 0.5 0.00015 21.9 0.1 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 GAX24423.1 - 0.00029 20.5 0.6 0.00052 19.6 0.2 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 GAX24423.1 - 0.0015 18.1 0.0 0.0047 16.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAX24423.1 - 0.0015 18.9 0.1 0.0064 16.9 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX24423.1 - 0.0018 18.3 0.1 0.0043 17.1 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 GAX24423.1 - 0.0028 16.9 0.0 0.61 9.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein TrkA_N PF02254.18 GAX24423.1 - 0.013 15.8 0.1 0.024 14.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 GAX24423.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 KR domain ABC_tran PF00005.27 GAX24424.1 - 5.7e-49 166.2 0.0 5.2e-25 88.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAX24424.1 - 6.6e-19 68.8 7.0 1.4e-08 35.0 0.0 4.6 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX24424.1 - 4.6e-06 26.2 0.0 0.25 10.8 0.0 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX24424.1 - 9.5e-05 22.3 0.0 1.4 8.6 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAX24424.1 - 0.00018 21.1 1.2 0.065 13.0 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX24424.1 - 0.00092 19.8 1.2 0.29 11.6 0.2 2.3 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 GAX24424.1 - 0.0036 18.0 0.3 0.31 11.8 0.0 3.6 4 0 0 4 4 3 1 Domain of unknown function (DUF4162) AAA_30 PF13604.6 GAX24424.1 - 0.0071 16.1 0.2 0.52 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX24424.1 - 0.031 13.9 0.4 7 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAX24424.1 - 0.047 13.6 0.7 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 GAX24424.1 - 0.065 13.2 0.8 6.3 6.8 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAX24424.1 - 0.076 13.2 0.1 20 5.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAX24424.1 - 0.14 11.4 1.3 20 4.4 0.1 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.6 GAX24424.1 - 0.16 12.4 0.2 9.8 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 GAX24424.1 - 0.17 10.5 4.1 0.2 10.3 0.1 2.5 3 0 0 3 3 3 0 AAA domain PHD PF00628.29 GAX24425.1 - 2.2e-11 43.5 8.5 4e-11 42.6 8.5 1.5 1 0 0 1 1 1 1 PHD-finger PWWP PF00855.17 GAX24425.1 - 4e-10 40.0 0.6 8e-10 39.0 0.1 1.7 2 0 0 2 2 2 1 PWWP domain PHD_2 PF13831.6 GAX24425.1 - 0.1 12.2 2.7 0.2 11.2 2.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 GAX24425.1 - 1.3 8.6 6.0 0.2 11.2 1.6 1.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 GAX24425.1 - 7.7 6.9 8.4 18 5.8 8.4 1.7 1 0 0 1 1 1 0 Ring finger domain Mito_carr PF00153.27 GAX24426.1 - 3.4e-44 148.7 7.4 6.5e-20 70.9 0.0 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Pam17 PF08566.10 GAX24426.1 - 0.21 11.5 0.6 4.3 7.2 0.3 2.5 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 DIRP PF06584.13 GAX24427.1 - 2.8e-10 40.3 0.1 2.2e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 DIRP DUF3400 PF11880.8 GAX24427.1 - 0.18 11.4 0.0 0.44 10.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) AAA_23 PF13476.6 GAX24428.1 - 1.8e-12 48.2 5.5 5.3e-11 43.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 GAX24428.1 - 2.6e-08 33.6 2.6 7.6e-05 22.3 0.5 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Metallophos PF00149.28 GAX24428.1 - 7.1e-08 33.2 0.2 1.4e-07 32.2 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX24428.1 - 0.00024 21.4 0.8 0.0022 18.2 0.1 2.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Snapin_Pallidin PF14712.6 GAX24428.1 - 0.0013 19.1 9.4 0.0037 17.7 4.8 3.4 2 0 0 2 2 2 1 Snapin/Pallidin SbcCD_C PF13558.6 GAX24428.1 - 0.0028 17.8 0.0 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit eIF-1a PF01176.19 GAX24428.1 - 0.031 14.1 0.1 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 DUF4127 PF13552.6 GAX24428.1 - 0.054 12.1 0.1 0.054 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) GAPES4 PF17157.4 GAX24428.1 - 0.36 11.2 2.2 3.1 8.3 1.2 3.0 3 0 0 3 3 3 0 Gammaproteobacterial periplasmic sensor domain ABC_tran PF00005.27 GAX24428.1 - 0.42 11.1 3.8 22 5.5 2.5 3.7 2 1 0 2 2 2 0 ABC transporter DUF1664 PF07889.12 GAX24428.1 - 3.4 7.7 11.4 0.15 12.1 2.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 GAX24428.1 - 8.7 6.4 11.6 2.1 8.3 5.8 2.9 2 1 1 3 3 3 0 Laminin Domain II zf-RING_2 PF13639.6 GAX24430.1 - 3.4e-07 30.5 6.4 8.6e-07 29.2 6.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX24430.1 - 3.2e-06 26.8 1.4 7.6e-06 25.6 0.8 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX24430.1 - 0.00016 21.5 3.9 0.0011 18.8 4.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX24430.1 - 0.00061 19.6 3.6 0.0018 18.1 3.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX24430.1 - 0.0012 18.8 5.9 0.0035 17.3 5.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX24430.1 - 0.0036 17.1 6.5 0.0092 15.8 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_MLP1_2 PF07926.12 GAX24430.1 - 0.015 15.4 17.8 0.015 15.4 17.8 3.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein zf-rbx1 PF12678.7 GAX24430.1 - 0.038 14.3 11.7 0.22 11.9 11.7 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain MAD PF05557.13 GAX24430.1 - 0.072 11.4 26.5 0.1 10.9 26.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein RE_AccI PF09545.10 GAX24430.1 - 0.078 11.9 0.8 0.12 11.3 0.8 1.3 1 0 0 1 1 1 0 AccI restriction endonuclease zf-ANAPC11 PF12861.7 GAX24430.1 - 0.098 12.7 5.1 0.21 11.7 5.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX24430.1 - 0.24 11.1 9.9 0.66 9.6 9.9 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX24430.1 - 0.53 10.2 10.6 0.66 9.9 8.7 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Filament PF00038.21 GAX24430.1 - 0.77 9.3 24.3 0.11 12.1 3.7 3.1 1 1 1 3 3 3 0 Intermediate filament protein zf-RING_5 PF14634.6 GAX24430.1 - 0.96 9.5 8.0 3.3 7.8 8.0 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Csm1_N PF18504.1 GAX24430.1 - 3.5 8.0 19.3 0.046 14.1 2.5 4.0 4 0 0 4 4 4 0 Csm1 N-terminal domain zf-C3HC4_4 PF15227.6 GAX24430.1 - 4.3 7.6 10.0 16 5.7 8.9 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Spermine_synth PF01564.17 GAX24431.1 - 1.3e-26 93.2 0.0 2.3e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 GAX24431.1 - 1.1e-22 80.2 0.0 2.5e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase SET PF00856.28 GAX24431.1 - 0.022 15.2 0.0 3 8.2 0.0 2.6 1 1 0 1 1 1 0 SET domain FAT PF02259.23 GAX24432.1 - 9.5e-32 110.5 6.7 1.8e-31 109.6 6.7 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 GAX24432.1 - 1.1e-16 61.5 0.0 2.7e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GAX24432.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 FATC domain Helicase_C PF00271.31 GAX24433.1 - 0.0014 19.0 0.2 0.023 15.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DNA_pol_E_B PF04042.16 GAX24434.1 - 8.8e-27 93.8 0.0 1.4e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 GAX24434.1 - 4.7e-21 75.2 0.0 4.2e-20 72.2 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Rubredoxin_2 PF18073.1 GAX24435.1 - 0.051 13.3 1.3 0.09 12.5 1.3 1.4 1 0 0 1 1 1 0 Rubredoxin metal binding domain Copine PF07002.16 GAX24436.1 - 3.5e-49 167.2 0.0 5.1e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAX24436.1 - 2e-11 44.1 0.0 3.5e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAX24436.1 - 0.00027 21.1 0.0 0.00086 19.5 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.28 GAX24436.1 - 0.0021 18.3 0.2 0.0044 17.3 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain TPR_12 PF13424.6 GAX24437.1 - 2.7e-30 104.5 0.6 2.5e-16 59.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24437.1 - 1e-19 69.5 5.1 8.2e-07 28.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX24437.1 - 1.1e-19 69.6 0.3 2e-06 27.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX24437.1 - 1.4e-16 59.2 5.9 0.0012 18.8 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX24437.1 - 6.2e-12 44.7 3.6 0.0017 18.4 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX24437.1 - 6.7e-12 44.6 0.1 0.00021 21.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX24437.1 - 2.2e-05 24.1 5.5 1.4 8.6 0.0 5.1 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 GAX24437.1 - 0.0001 22.4 0.1 0.032 14.4 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX24437.1 - 0.00012 22.6 1.0 17 6.2 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX24437.1 - 0.0011 18.4 2.4 0.0011 18.4 2.4 1.8 2 0 0 2 2 2 1 MalT-like TPR region PPR PF01535.20 GAX24437.1 - 0.0031 17.6 0.3 4.1 7.9 0.0 3.9 4 1 1 5 5 4 1 PPR repeat TPR_17 PF13431.6 GAX24437.1 - 0.01 16.2 0.4 10 6.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX24437.1 - 0.014 16.0 5.1 1.1 10.0 0.0 4.2 5 1 0 5 5 4 0 Tetratricopeptide repeat DUF5113 PF17140.4 GAX24437.1 - 0.021 14.7 0.2 0.043 13.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) TPR_14 PF13428.6 GAX24437.1 - 0.062 14.2 5.8 31 5.7 0.0 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat SPO22 PF08631.10 GAX24437.1 - 0.079 12.4 0.0 0.82 9.1 0.0 2.1 1 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like RPN7 PF10602.9 GAX24437.1 - 0.11 12.1 0.1 1.3 8.7 0.1 2.2 1 1 0 2 2 2 0 26S proteasome subunit RPN7 GAIN_A PF18619.1 GAX24437.1 - 0.42 10.8 4.1 0.25 11.6 0.5 2.3 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A MatE PF01554.18 GAX24438.1 - 3.4e-30 104.8 21.6 5.1e-18 65.2 3.7 3.0 3 0 0 3 3 3 2 MatE TPR_2 PF07719.17 GAX24440.1 - 5.1e-05 23.1 1.2 0.066 13.4 0.4 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24440.1 - 0.033 14.0 0.8 0.37 10.7 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Band_7_C PF16200.5 GAX24440.1 - 0.097 12.7 0.5 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 C-terminal region of band_7 TPR_12 PF13424.6 GAX24440.1 - 0.2 12.0 2.5 0.92 9.8 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 GAX24441.1 - 3.2e-08 34.1 0.0 6.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Syntaxin PF00804.25 GAX24442.1 - 5.9e-07 29.4 8.2 0.00029 20.6 1.6 2.3 2 0 0 2 2 2 2 Syntaxin SNARE PF05739.19 GAX24442.1 - 5.1e-06 26.4 9.2 1.7e-05 24.7 2.1 2.4 2 0 0 2 2 2 1 SNARE domain Apolipoprotein PF01442.18 GAX24442.1 - 0.00028 20.8 2.9 0.00028 20.8 2.9 2.4 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Dynamin_M PF01031.20 GAX24442.1 - 0.0058 15.9 0.6 0.0058 15.9 0.6 1.5 2 0 0 2 2 2 1 Dynamin central region AAA_13 PF13166.6 GAX24442.1 - 0.0061 15.3 7.5 0.018 13.7 1.4 2.0 2 0 0 2 2 2 2 AAA domain SF-assemblin PF06705.11 GAX24442.1 - 0.011 15.1 7.6 0.099 12.0 1.1 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin ApoLp-III PF07464.11 GAX24442.1 - 0.025 14.7 8.5 0.23 11.5 2.5 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Filament PF00038.21 GAX24442.1 - 0.036 13.6 10.6 0.53 9.8 1.5 2.2 2 0 0 2 2 2 0 Intermediate filament protein Borrelia_lipo_1 PF05714.11 GAX24442.1 - 0.088 12.6 2.0 0.12 12.1 0.3 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein RsbU_N PF08673.10 GAX24442.1 - 0.089 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Syntaxin_2 PF14523.6 GAX24442.1 - 0.094 13.1 8.8 1.1 9.7 2.6 2.8 2 1 1 3 3 3 0 Syntaxin-like protein Tom5 PF10642.9 GAX24442.1 - 0.15 12.1 0.9 0.89 9.6 0.0 2.7 3 0 0 3 3 2 0 Mitochondrial import receptor subunit or translocase YtxH PF12732.7 GAX24442.1 - 0.36 11.4 3.3 0.4 11.3 0.9 2.3 2 1 0 2 2 2 0 YtxH-like protein CSN5_C PF18323.1 GAX24442.1 - 0.41 11.6 4.3 0.28 12.1 1.7 2.0 2 0 0 2 2 1 0 Cop9 signalosome subunit 5 C-terminal domain Prominin PF05478.11 GAX24442.1 - 0.49 8.3 6.2 1.3 6.9 0.5 2.1 2 0 0 2 2 2 0 Prominin Latarcin PF10279.9 GAX24442.1 - 0.55 10.7 6.7 1.1 9.8 0.2 2.9 2 1 0 2 2 2 0 Latarcin precursor Allexi_40kDa PF05549.11 GAX24442.1 - 0.64 9.5 6.3 0.69 9.4 0.5 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Nup88 PF10168.9 GAX24442.1 - 0.8 7.4 9.0 0.023 12.5 2.7 1.5 2 0 0 2 2 2 0 Nuclear pore component SKA1 PF07160.12 GAX24442.1 - 1.1 9.1 8.2 2.8 7.7 1.3 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF724 PF05266.14 GAX24442.1 - 1.7 8.4 7.7 2.2 8.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4047 PF13256.6 GAX24442.1 - 2 8.7 5.5 0.99 9.6 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF16 PF01519.16 GAX24442.1 - 2.2 8.8 9.8 1.3 9.5 1.6 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Laminin_II PF06009.12 GAX24442.1 - 2.3 8.2 9.0 3.3 7.7 0.7 3.2 2 1 1 3 3 3 0 Laminin Domain II Baculo_p24 PF05073.12 GAX24442.1 - 2.6 7.8 6.4 1.9 8.2 0.9 2.2 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Tup_N PF08581.10 GAX24442.1 - 6.1 7.2 13.1 1.5 9.2 2.2 3.4 2 1 1 3 3 3 0 Tup N-terminal BST2 PF16716.5 GAX24442.1 - 7.3 7.3 10.7 3.3 8.4 1.5 2.6 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 WD40 PF00400.32 GAX24443.1 - 7.5e-16 58.2 9.7 3.1e-05 24.6 0.0 8.1 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX24443.1 - 6.9e-12 45.5 0.0 2.4e-05 24.5 0.0 4.9 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX24443.1 - 0.0051 17.3 0.4 4 8.1 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain Utp21 PF04192.12 GAX24443.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Ge1_WD40 PF16529.5 GAX24443.1 - 0.032 13.2 0.0 0.078 11.9 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAX24443.1 - 0.034 12.7 0.0 0.059 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Inhibitor_I29 PF08246.12 GAX24444.1 - 6.8e-05 23.2 14.2 0.02 15.3 2.7 3.3 3 0 0 3 3 3 2 Cathepsin propeptide inhibitor domain (I29) Nucleoporin_FG PF13634.6 GAX24444.1 - 0.0004 21.2 8.0 0.014 16.2 7.9 3.4 1 1 0 1 1 1 1 Nucleoporin FG repeat region DUF3449 PF11931.8 GAX24445.1 - 2.1e-63 213.4 0.0 3.8e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 GAX24445.1 - 1.5e-20 72.6 3.1 1.8e-20 72.3 1.8 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal SF3A3 PF16837.5 GAX24445.1 - 7.6e-12 45.6 0.1 1.4e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Abhydrolase_1 PF00561.20 GAX24446.1 - 4.2e-18 65.9 0.0 2.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX24446.1 - 2.9e-17 64.0 0.2 4.2e-17 63.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX24446.1 - 7e-15 54.9 0.0 6e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 GAX24446.1 - 4.1e-07 29.8 0.0 6.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 GAX24446.1 - 2e-05 24.4 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 GAX24446.1 - 0.00027 20.9 0.0 0.0045 16.9 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.7 GAX24446.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GAX24446.1 - 0.0023 18.1 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 GAX24446.1 - 0.004 17.0 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 GAX24446.1 - 0.0056 16.4 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 GAX24446.1 - 0.026 13.9 0.0 0.089 12.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 GAX24446.1 - 0.026 13.2 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family UPF0227 PF05728.12 GAX24446.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2048 PF09752.9 GAX24446.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 HSP90 PF00183.18 GAX24447.1 - 6.3e-109 365.2 1.2 1.1e-103 347.9 0.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 GAX24447.1 - 2.5e-07 30.6 0.0 5.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAX24447.1 - 6.4e-06 26.7 0.2 1.2e-05 25.7 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro2_C5 PF18565.1 GAX24447.1 - 0.091 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 FerB PF08150.12 GAX24448.1 - 0.15 12.7 0.0 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 FerB (NUC096) domain Mg_chelatase PF01078.21 GAX24449.1 - 0.097 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PsbP PF01789.16 GAX24450.1 - 3.2e-20 72.8 0.0 4.3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 PsbP Na_Pi_cotrans PF02690.15 GAX24451.1 - 2.8e-37 127.9 30.7 4.2e-21 75.5 10.6 2.5 2 1 0 2 2 2 2 Na+/Pi-cotransporter NQRA_SLBB PF11973.8 GAX24451.1 - 0.13 12.9 3.2 0.24 12.0 0.4 2.8 3 0 0 3 3 3 0 NQRA C-terminal domain Na_Pi_cotrans PF02690.15 GAX24453.1 - 1.5e-36 125.6 33.1 6.8e-22 78.1 9.0 2.8 2 1 1 3 3 3 2 Na+/Pi-cotransporter NDUF_C2 PF06374.11 GAX24454.1 - 0.077 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) MPC PF03650.13 GAX24454.1 - 0.13 12.4 0.4 0.19 11.9 0.3 1.4 1 1 0 1 1 1 0 Mitochondrial pyruvate carriers Toxin_35 PF10530.9 GAX24456.1 - 0.00025 21.0 2.7 0.00025 21.0 2.7 11.6 4 4 7 11 11 11 3 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_12 PF07740.12 GAX24456.1 - 0.033 14.9 4.6 0.033 14.9 4.6 14.0 13 1 0 14 14 14 0 Ion channel inhibitory toxin FAM163 PF15069.6 GAX24457.1 - 0.00014 22.4 0.0 0.00017 22.0 0.0 1.1 1 0 0 1 1 1 1 FAM163 family T2SSF PF00482.23 GAX24457.1 - 0.35 10.8 1.9 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Ribonuclease_3 PF00636.26 GAX24458.1 - 8.3e-35 119.6 0.0 9.6e-18 64.7 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAX24458.1 - 1.6e-19 70.4 0.0 8.1e-10 39.0 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease-III-like ResIII PF04851.15 GAX24458.1 - 3.3e-14 53.2 0.0 9.7e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX24458.1 - 9.9e-14 51.6 0.9 3.6e-13 49.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX24458.1 - 3e-13 49.9 0.0 6.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 GAX24458.1 - 1.3e-05 25.2 0.1 4.7e-05 23.5 0.1 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain AAA_19 PF13245.6 GAX24458.1 - 0.00018 21.9 0.0 0.00063 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX24458.1 - 0.0012 18.0 0.1 0.0024 17.0 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Spore_II_R PF09551.10 GAX24458.1 - 0.0054 17.2 0.0 0.049 14.1 0.0 2.7 2 0 0 2 2 2 1 Stage II sporulation protein R (spore_II_R) AAA_22 PF13401.6 GAX24458.1 - 0.0095 16.2 0.8 0.032 14.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAX24458.1 - 0.015 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Piwi PF02171.17 GAX24459.1 - 1.2e-36 126.5 0.0 2.3e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 GAX24459.1 - 8.4e-09 35.4 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain zf-C2H2_2 PF12756.7 GAX24459.1 - 0.0032 17.8 0.1 0.0071 16.7 0.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AAA_26 PF13500.6 GAX24459.1 - 0.19 11.6 0.3 0.48 10.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain DDE_Tnp_4 PF13359.6 GAX24463.1 - 2.1e-12 47.0 0.0 3.3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAX24463.1 - 1.1e-06 28.5 0.7 1.1e-05 25.2 0.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain S6PP_C PF08472.10 GAX24463.1 - 0.013 15.4 1.1 5.2 7.0 0.0 2.8 3 0 0 3 3 3 0 Sucrose-6-phosphate phosphohydrolase C-terminal Ank_2 PF12796.7 GAX24465.1 - 8.7e-12 45.5 0.0 0.027 15.1 0.0 4.4 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAX24465.1 - 3.2e-07 30.5 0.1 3.4 8.3 0.0 6.0 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 GAX24465.1 - 5.3e-06 26.9 0.1 8.2 7.1 0.0 4.6 3 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX24465.1 - 0.00011 22.3 0.0 7.9 7.4 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 GAX24465.1 - 0.00081 19.6 2.3 76 3.8 0.0 6.5 7 2 1 8 8 8 0 Ankyrin repeats (many copies) PET PF06297.14 GAX24465.1 - 0.12 12.7 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 PET Domain Ank_2 PF12796.7 GAX24466.1 - 2.5e-07 31.2 0.1 1.3 9.6 0.0 4.2 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAX24466.1 - 9.4e-06 25.8 0.1 0.88 10.1 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 GAX24466.1 - 2.8e-05 24.6 0.1 14 6.4 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX24466.1 - 0.00045 20.5 0.5 68 4.5 0.0 6.3 8 0 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 GAX24466.1 - 0.00069 19.9 2.0 0.68 10.3 0.0 5.4 7 0 0 7 7 7 1 Ankyrin repeats (many copies) DUF1415 PF07209.12 GAX24467.1 - 1.9e-17 63.5 0.2 2.2e-17 63.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) SAM_MT PF04445.13 GAX24467.1 - 0.03 13.8 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DUF285 PF03382.14 GAX24468.1 - 1.5e-57 192.6 25.6 6.4e-30 103.4 7.9 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 RVT_1 PF00078.27 GAX24469.1 - 2.9e-08 33.5 0.1 9.1e-08 31.9 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GAX24469.1 - 0.00047 20.8 1.6 0.0021 18.8 1.6 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase V_ATPase_I PF01496.19 GAX24469.1 - 0.0055 14.7 1.8 0.012 13.6 1.8 1.5 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family BRE1 PF08647.11 GAX24469.1 - 0.11 12.5 6.9 0.41 10.8 6.9 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Spidroin_N PF16763.5 GAX24469.1 - 0.29 11.1 3.2 3.4 7.7 0.1 2.8 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term HA PF03457.14 GAX24470.1 - 8.3e-29 99.7 19.1 3e-09 37.1 0.8 4.6 3 1 1 4 4 4 4 Helicase associated domain DUF3303 PF11746.8 GAX24470.1 - 0.02 15.2 0.1 2.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3303) Response_reg PF00072.24 GAX24471.1 - 3.6e-25 88.3 0.7 9.3e-25 87.0 0.7 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAX24471.1 - 3.1e-23 82.4 0.1 1e-22 80.8 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HNOBA PF07701.14 GAX24471.1 - 4.9e-21 75.2 2.9 2.1e-18 66.6 0.8 2.9 2 1 0 2 2 2 1 Heme NO binding associated HisKA PF00512.25 GAX24471.1 - 6.2e-11 42.2 0.1 3.4e-10 39.8 0.0 2.4 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAX24471.1 - 0.00059 19.7 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.14 GAX24472.1 - 0.28 9.4 0.7 0.32 9.2 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein YbgS PF13985.6 GAX24472.1 - 2.7 8.3 4.5 1.2 9.5 1.5 1.9 2 0 0 2 2 2 0 YbgS-like protein Trypan_PARP PF05887.11 GAX24472.1 - 7.2 6.6 20.9 0.41 10.6 14.6 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DDE_Tnp_4 PF13359.6 GAX24473.1 - 7.8e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HNOB PF07700.15 GAX24474.1 - 3.5e-38 131.1 0.0 5.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 GAX24475.1 - 2e-44 151.4 0.0 3.6e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX24475.1 - 8.5e-33 114.0 2.5 1.8e-32 112.9 2.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF285 PF03382.14 GAX24476.1 - 3.4e-58 194.7 22.3 6e-31 106.7 4.9 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 CBM_25 PF03423.13 GAX24476.1 - 1 9.7 7.4 3.5 7.9 1.4 3.5 1 1 3 4 4 4 0 Carbohydrate binding domain (family 25) DUF285 PF03382.14 GAX24477.1 - 6.3e-132 432.7 41.8 9.5e-38 128.7 10.1 4.2 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 DUF285 PF03382.14 GAX24478.1 - 1.4e-120 396.1 63.0 1.6e-35 121.4 7.3 3.0 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 Terpene_synth_C PF03936.16 GAX24478.1 - 0.005 16.2 0.2 5.2 6.3 0.0 3.6 2 1 2 4 4 4 2 Terpene synthase family, metal binding domain FeoB_N PF02421.18 GAX24478.1 - 0.047 13.2 3.9 9.3 5.8 0.2 3.9 1 1 2 4 4 4 0 Ferrous iron transport protein B U5_2-snRNA_bdg PF10597.9 GAX24478.1 - 0.07 13.2 7.0 1 9.4 0.5 3.9 1 1 4 5 5 5 0 U5-snRNA binding site 2 of PrP8 FANCI_S1 PF14675.6 GAX24478.1 - 0.92 9.0 3.0 43 3.6 0.1 3.8 2 1 1 4 4 4 0 FANCI solenoid 1 DUF4035 PF13227.6 GAX24478.1 - 1.1 9.0 3.7 1.7 8.4 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4035) DUF285 PF03382.14 GAX24479.1 - 5.5e-94 310.2 36.9 1.8e-36 124.6 9.7 3.1 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 DUF1108 PF06531.11 GAX24479.1 - 0.00027 21.2 0.2 28 5.1 0.0 5.0 2 2 3 6 6 6 2 Protein of unknown function (DUF1108) DUF1415 PF07209.12 GAX24480.1 - 1.8e-35 122.2 0.1 2.1e-35 122.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) DUF3710 PF12502.8 GAX24480.1 - 0.21 11.2 1.7 2.8 7.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3710) CPSase_L_D2 PF02786.17 GAX24481.1 - 2.7e-68 229.6 0.0 5.3e-68 228.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 GAX24481.1 - 1.6e-47 161.9 0.1 4.9e-31 108.0 0.0 2.5 1 1 1 2 2 2 2 Conserved carboxylase domain Biotin_carb_N PF00289.22 GAX24481.1 - 6.7e-36 123.2 0.3 8.4e-35 119.7 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAX24481.1 - 1.9e-32 111.6 0.0 6.2e-32 109.9 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 GAX24481.1 - 1.2e-28 100.4 0.0 2.2e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 GAX24481.1 - 2.6e-17 62.4 5.6 2.9e-17 62.3 3.1 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAX24481.1 - 1e-12 47.7 0.3 6.8e-06 25.8 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAX24481.1 - 8.9e-12 45.0 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 GAX24481.1 - 7.1e-07 29.9 1.3 0.058 14.1 0.0 3.3 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 GAX24481.1 - 8.8e-07 28.4 0.3 0.016 14.5 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp PF02222.22 GAX24481.1 - 9.2e-07 28.6 0.0 3e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAX24481.1 - 0.00063 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 GAX24481.1 - 0.0066 16.4 0.3 0.017 15.1 0.3 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATP-grasp_4 PF13535.6 GAX24481.1 - 0.013 15.1 0.0 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain NQRA PF05896.11 GAX24481.1 - 0.014 14.8 0.2 0.026 14.0 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) TTL PF03133.15 GAX24481.1 - 0.015 14.4 0.0 0.035 13.2 0.0 1.5 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family PTS_EIIA_1 PF00358.20 GAX24481.1 - 0.027 14.2 0.2 0.62 9.8 0.1 2.5 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 GCV_H PF01597.19 GAX24481.1 - 0.24 11.3 1.1 1.1 9.2 0.4 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein Pyrid_oxidase_2 PF13883.6 GAX24487.1 - 6.6e-41 140.1 0.0 3.5e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase DUF285 PF03382.14 GAX24488.1 - 2.8e-57 191.7 16.8 1.3e-38 131.4 4.5 1.6 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 CBM_5_12_2 PF14600.6 GAX24488.1 - 0.068 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Cellulose-binding domain DUF285 PF03382.14 GAX24489.1 - 8.6e-90 296.7 32.0 2.7e-34 117.5 2.4 3.2 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 PhyH PF05721.13 GAX24490.1 - 2e-40 139.3 0.0 3.1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAX24490.1 - 0.017 15.6 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF285 PF03382.14 GAX24491.1 - 7.2e-62 206.5 25.3 5e-34 116.7 6.2 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Fasciclin PF02469.22 GAX24492.1 - 3.3e-23 82.3 0.0 1.1e-13 51.5 0.1 3.5 3 0 0 3 3 3 3 Fasciclin domain AFG1_ATPase PF03969.16 GAX24493.1 - 4.7e-89 298.8 0.0 5.8e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 GAX24493.1 - 0.0016 18.9 0.1 0.91 9.9 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 GAX24493.1 - 0.012 15.6 0.0 0.098 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 GAX24493.1 - 0.039 13.8 0.1 0.69 9.7 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.6 GAX24493.1 - 0.041 14.2 0.2 0.96 9.7 0.0 2.9 2 2 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAX24493.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF5333 PF17267.2 GAX24495.1 - 0.059 13.5 0.1 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5333) SF3b1 PF08920.10 GAX24495.1 - 0.063 13.8 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 DUF2025 PF09634.10 GAX24499.1 - 0.056 13.5 0.1 0.096 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) DUF1800 PF08811.11 GAX24501.1 - 5.4e-43 147.6 0.0 4e-25 88.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX24501.1 - 8e-33 114.1 0.0 1.5e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX24501.1 - 0.0015 18.7 0.0 0.0042 17.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Njmu-R1 PF15053.6 GAX24504.1 - 0.023 13.8 0.5 0.029 13.5 0.5 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family FAM76 PF16046.5 GAX24505.1 - 0.0042 16.5 4.4 0.0059 16.0 4.4 1.1 1 0 0 1 1 1 1 FAM76 protein MLANA PF14991.6 GAX24505.1 - 0.0087 16.3 0.9 0.0087 16.3 0.9 1.6 1 1 0 1 1 1 1 Protein melan-A V_ATPase_I PF01496.19 GAX24505.1 - 0.085 10.8 0.2 0.11 10.4 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Anoctamin PF04547.12 GAX24505.1 - 0.095 11.5 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Glycophorin_A PF01102.18 GAX24505.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A Neur_chan_memb PF02932.16 GAX24505.1 - 0.12 12.5 0.4 0.16 12.0 0.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EphA2_TM PF14575.6 GAX24505.1 - 0.13 13.1 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_67C PF07477.12 GAX24505.1 - 0.15 11.5 1.3 0.25 10.9 1.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus NeA_P2 PF12312.8 GAX24505.1 - 0.26 10.7 0.0 0.26 10.7 0.0 1.5 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein EMC3_TMCO1 PF01956.16 GAX24505.1 - 0.28 10.9 1.8 0.51 10.1 1.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TMEM51 PF15345.6 GAX24505.1 - 1.1 9.1 4.1 2.4 7.9 4.1 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 O-FucT PF10250.9 GAX24506.1 - 0.018 14.7 0.0 0.051 13.3 0.0 1.4 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Thioredoxin PF00085.20 GAX24507.1 - 4.3e-22 78.0 0.0 5.4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 GAX24507.1 - 8.2e-07 29.0 0.0 5.5e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 GAX24507.1 - 5.4e-06 26.5 0.0 9.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX24507.1 - 2.7e-05 24.4 0.0 0.0058 16.9 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 GAX24507.1 - 6.8e-05 22.6 0.0 8.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 GAX24507.1 - 0.00022 21.6 0.1 0.002 18.6 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GAX24507.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 GAX24507.1 - 0.0094 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAX24507.1 - 0.045 13.5 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 GAX24507.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 GAX24507.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain adh_short_C2 PF13561.6 GAX24508.1 - 4.2e-54 183.6 3.1 3.6e-53 180.5 3.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX24508.1 - 4.2e-49 166.7 1.0 5.3e-49 166.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX24508.1 - 2.1e-09 37.6 0.8 3.1e-09 37.0 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX24508.1 - 1.4e-07 31.2 0.1 3.4e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX24508.1 - 0.0064 15.9 0.1 0.013 14.9 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX24508.1 - 0.03 13.5 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX24508.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CoA_binding_2 PF13380.6 GAX24508.1 - 0.11 13.0 0.0 0.57 10.7 0.0 2.1 2 1 0 2 2 2 0 CoA binding domain Lactonase PF10282.9 GAX24509.1 - 1.3e-62 212.1 0.0 1.4e-61 208.7 0.0 2.0 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller AhpC-TSA PF00578.21 GAX24510.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX24510.1 - 0.00081 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin YqzH PF14164.6 GAX24510.1 - 0.52 10.4 2.0 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 YqzH-like protein Bestrophin PF01062.21 GAX24511.1 - 2.4e-18 66.6 3.2 3.4e-16 59.5 0.1 2.1 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel SprA_N PF14349.6 GAX24512.1 - 0.072 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Motility related/secretion protein LRR_8 PF13855.6 GAX24514.1 - 9.7e-26 89.3 34.8 1.9e-06 27.5 5.6 6.5 3 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX24514.1 - 1.4e-23 82.6 35.9 2.1e-05 24.8 0.0 8.6 5 2 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX24514.1 - 6.7e-12 44.2 20.9 0.094 13.3 0.0 10.0 10 2 1 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.6 GAX24514.1 - 7.9e-08 31.8 25.2 1.6 9.0 0.0 10.1 10 0 0 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.6 GAX24514.1 - 2.4 7.6 8.9 6 6.3 1.3 3.3 2 1 0 3 3 3 0 Leucine-rich repeat TPR_12 PF13424.6 GAX24515.1 - 4.3e-31 107.0 11.9 1e-14 54.5 0.9 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24515.1 - 6.3e-24 82.8 5.5 1.6e-06 27.6 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX24515.1 - 9.2e-21 72.2 10.7 1.5e-05 24.8 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX24515.1 - 1.7e-20 72.2 12.2 1.3e-07 31.3 0.4 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX24515.1 - 2.1e-15 55.6 3.5 6.6e-05 22.8 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX24515.1 - 2.2e-11 42.9 4.1 0.004 17.1 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX24515.1 - 3.1e-07 30.7 6.9 0.15 13.0 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX24515.1 - 4.3e-07 30.1 4.1 0.93 10.3 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX24515.1 - 3.6e-06 27.5 5.0 0.0025 18.4 0.1 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX24515.1 - 1.3e-05 24.8 8.2 0.0043 16.7 0.2 4.7 4 1 1 5 5 5 2 TPR repeat TPR_MalT PF17874.1 GAX24515.1 - 3.2e-05 23.5 4.9 3.2e-05 23.5 4.9 2.3 1 1 0 2 2 2 1 MalT-like TPR region ANAPC5 PF12862.7 GAX24515.1 - 3.6e-05 23.7 8.4 0.0089 16.1 3.9 4.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 GAX24515.1 - 7.8e-05 22.8 0.2 5.7 7.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX24515.1 - 0.00021 21.7 6.8 0.47 11.0 0.4 4.1 2 1 3 5 5 5 3 Tetratricopeptide repeat MIT PF04212.18 GAX24515.1 - 0.0014 18.6 0.5 1.9 8.7 0.2 3.4 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 GAX24515.1 - 0.014 15.5 0.2 0.014 15.5 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX24515.1 - 0.017 15.2 1.9 6.9 6.8 0.0 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat RICTOR_phospho PF14665.6 GAX24515.1 - 0.033 14.5 1.6 0.039 14.3 0.3 1.8 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site TPR_20 PF14561.6 GAX24515.1 - 0.043 14.1 9.9 0.19 12.1 0.1 4.6 3 2 1 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX24515.1 - 0.14 12.4 3.8 4.6 7.5 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 GAX24515.1 - 0.21 11.9 1.4 0.38 11.1 0.1 2.2 2 0 0 2 2 1 0 PPR repeat TPR_4 PF07721.14 GAX24515.1 - 0.23 12.2 9.1 1.3 9.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX24515.1 - 0.4 10.3 3.3 23 4.6 0.1 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain Pro_isomerase PF00160.21 GAX24516.1 - 4.2e-36 124.6 0.0 4.9e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Plant_vir_prot PF01307.17 GAX24516.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Plant viral movement protein DEAD PF00270.29 GAX24517.1 - 5.7e-35 120.7 0.0 1.1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX24517.1 - 8.8e-32 109.8 0.3 6.3e-31 107.0 0.2 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 GAX24517.1 - 0.0075 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 GAX24517.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SNARE_assoc PF09335.11 GAX24518.1 - 6.8e-16 58.8 2.7 1.6e-15 57.6 2.7 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF4235 PF14019.6 GAX24518.1 - 0.093 12.8 0.1 0.093 12.8 0.1 3.9 6 0 0 6 6 6 0 Protein of unknown function (DUF4235) Cellulase PF00150.18 GAX24520.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Metallophos PF00149.28 GAX24521.1 - 3.1e-09 37.7 4.2 5.4e-09 36.9 4.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 GAX24521.1 - 0.0032 17.7 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain HSF_DNA-bind PF00447.17 GAX24522.1 - 1.3e-16 61.0 0.1 2.3e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding mRNA_triPase PF02940.15 GAX24522.1 - 0.13 12.0 0.2 0.27 10.9 0.0 1.5 2 0 0 2 2 2 0 mRNA capping enzyme, beta chain LRR_8 PF13855.6 GAX24523.1 - 5e-32 109.5 39.9 2.5e-10 40.0 0.1 7.0 4 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX24523.1 - 1.6e-23 82.4 40.0 5.5e-05 23.4 1.7 8.2 4 3 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX24523.1 - 1.7e-07 30.8 29.3 0.87 10.4 0.2 11.4 13 0 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.6 GAX24523.1 - 7.5e-05 22.5 31.7 0.073 13.2 0.0 9.9 11 0 0 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.6 GAX24523.1 - 0.0029 17.1 13.5 0.51 9.8 0.2 4.5 2 2 3 5 5 5 2 Leucine-rich repeat Tom7 PF08038.12 GAX24523.1 - 0.021 14.5 0.4 0.065 12.9 0.4 1.8 1 0 0 1 1 1 0 TOM7 family EMP70 PF02990.16 GAX24524.1 - 5.4e-183 609.4 7.6 5.4e-183 609.4 7.6 1.6 1 1 1 2 2 2 1 Endomembrane protein 70 DUF4381 PF14316.6 GAX24524.1 - 0.85 9.9 0.0 0.85 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Phage_holin_2_1 PF04971.12 GAX24524.1 - 2.1 8.4 7.8 1 9.4 1.5 2.7 2 0 0 2 2 2 0 Bacteriophage P21 holin S MCM PF00493.23 GAX24525.1 - 9.8e-99 329.0 0.0 1.5e-98 328.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX24525.1 - 2.4e-34 117.9 0.0 4.3e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX24525.1 - 2.5e-23 82.3 0.9 6.8e-23 80.9 0.9 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAX24525.1 - 1.2e-17 64.4 0.2 7.8e-17 61.8 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.8 GAX24525.1 - 5.4e-10 39.8 39.0 5.4e-10 39.8 39.0 4.6 3 1 1 4 4 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 GAX24525.1 - 5.4e-09 35.7 0.0 7.1e-07 28.8 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX24525.1 - 4.9e-07 29.8 0.0 1.8e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAX24525.1 - 0.00043 20.1 0.0 0.0038 17.1 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 GAX24525.1 - 0.008 16.0 0.0 0.076 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 GAX24525.1 - 0.028 14.1 0.1 0.22 11.2 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 GAX24525.1 - 0.098 13.1 0.0 0.47 10.9 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Snf7 PF03357.21 GAX24526.1 - 9.8e-42 142.5 5.3 1.2e-41 142.2 5.3 1.1 1 0 0 1 1 1 1 Snf7 HBM PF16591.5 GAX24526.1 - 0.0026 17.2 0.5 0.0026 17.2 0.5 2.0 1 1 1 2 2 2 1 Helical bimodular sensor domain Med4 PF10018.9 GAX24526.1 - 0.031 14.0 1.6 0.035 13.8 0.5 1.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 SlyX PF04102.12 GAX24526.1 - 0.043 14.4 4.1 14 6.4 0.3 3.7 1 1 4 5 5 4 0 SlyX DUF4094 PF13334.6 GAX24526.1 - 0.14 12.6 2.4 1.7 9.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF1943 PF09172.11 GAX24526.1 - 0.18 11.0 4.3 1.3 8.2 4.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) TMF_DNA_bd PF12329.8 GAX24526.1 - 0.21 11.6 0.3 0.21 11.6 0.3 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 GAX24526.1 - 0.52 10.3 6.1 1.2 9.2 0.1 3.2 1 1 2 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 GAX24526.1 - 0.9 10.0 3.6 25 5.3 0.1 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 GAX24526.1 - 2.1 8.9 4.8 16 6.0 0.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GvpK PF05121.12 GAX24526.1 - 3 7.9 8.7 5.9 7.0 4.9 3.1 3 1 0 3 3 3 0 Gas vesicle protein K Ion_trans_2 PF07885.16 GAX24527.1 - 2.7e-28 97.7 23.0 2.8e-14 52.8 7.7 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 GAX24527.1 - 1.9e-06 27.3 2.3 0.0053 16.0 0.2 2.3 2 0 0 2 2 2 2 Ion transport protein RcbX PF02341.15 GAX24528.1 - 0.038 14.3 0.2 0.44 10.8 0.0 2.5 2 0 0 2 2 2 0 RbcX protein IMUP PF15761.5 GAX24528.1 - 5.2 7.8 9.1 20 5.9 0.9 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Peptidase_M16_C PF05193.21 GAX24529.1 - 1.3e-37 129.6 0.0 3.4e-20 72.8 0.0 3.3 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAX24529.1 - 6.3e-15 55.4 0.0 1.5e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sdh_cyt PF01127.22 GAX24530.1 - 2.3e-16 59.9 0.3 3.1e-16 59.5 0.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit COX6C PF02937.15 GAX24531.1 - 0.00079 19.5 0.1 0.0011 19.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc Sedlin_N PF04628.13 GAX24532.1 - 3.4e-20 72.5 0.0 6.3e-20 71.6 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAX24532.1 - 4.9e-06 26.5 0.0 5.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Rotamase PF00639.21 GAX24533.1 - 2.5e-09 37.9 0.0 3.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX24533.1 - 2.8e-07 31.1 0.0 4.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Flg_hook PF02120.16 GAX24534.1 - 0.038 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK EF-hand_7 PF13499.6 GAX24535.1 - 7.1e-11 42.4 2.1 3e-05 24.4 0.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAX24535.1 - 7.7e-08 32.1 0.2 5.9e-06 26.0 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX24535.1 - 4.6e-07 29.2 6.4 0.55 10.3 0.1 4.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 GAX24535.1 - 6.1e-06 25.4 8.4 0.014 14.9 0.0 4.7 4 1 1 5 5 5 1 EF hand EF-hand_9 PF14658.6 GAX24535.1 - 9.7e-06 25.8 0.0 0.11 12.8 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain Glyco_trans_1_2 PF13524.6 GAX24535.1 - 0.0014 19.0 0.1 0.0036 17.7 0.1 1.7 1 1 1 2 2 2 1 Glycosyl transferases group 1 SCF PF02404.15 GAX24535.1 - 0.015 14.6 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Stem cell factor Smoothelin PF12510.8 GAX24535.1 - 0.02 15.0 1.6 0.11 12.6 0.4 2.4 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein E3_UFM1_ligase PF09743.9 GAX24535.1 - 0.055 13.1 0.0 0.085 12.5 0.0 1.5 1 1 0 1 1 1 0 E3 UFM1-protein ligase 1 EF-hand_like PF09279.11 GAX24535.1 - 0.069 13.7 0.5 0.81 10.2 0.1 2.6 1 1 2 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like DUF4093 PF13331.6 GAX24535.1 - 0.071 13.6 1.0 6.4 7.3 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4093) EFhand_Ca_insen PF08726.10 GAX24535.1 - 0.075 13.1 0.3 0.4 10.8 0.1 2.2 2 1 1 3 3 3 0 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 GAX24535.1 - 0.25 10.9 2.1 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 EF hand MMADHC PF10229.9 GAX24536.1 - 1.5e-27 97.0 0.0 1.8e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Acyl-CoA_dh_1 PF00441.24 GAX24537.1 - 3.5e-31 108.4 0.7 6.3e-31 107.6 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX24537.1 - 1.3e-26 93.4 0.0 2.5e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAX24537.1 - 1.1e-21 76.8 0.0 1.9e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAX24537.1 - 4.5e-08 33.5 0.3 1e-07 32.3 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain CS PF04969.16 GAX24539.1 - 6e-12 46.4 0.1 1.7e-11 45.0 0.0 1.8 2 0 0 2 2 2 1 CS domain Ank_3 PF13606.6 GAX24540.1 - 1.2e-06 28.3 0.0 0.034 14.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAX24540.1 - 3.3e-06 27.5 0.0 4.3e-05 24.0 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX24540.1 - 3e-05 24.5 0.0 7.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX24540.1 - 0.01 16.1 0.1 0.33 11.3 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 GAX24540.1 - 0.051 14.0 0.0 5.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat DUF5305 PF17231.2 GAX24540.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) dCMP_cyt_deam_1 PF00383.23 GAX24541.1 - 2.9e-20 72.0 3.5 1.9e-19 69.4 3.5 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX24541.1 - 1.4e-17 63.7 0.1 5.6e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 GAX24541.1 - 0.011 15.8 4.6 1.3 9.1 2.5 2.3 1 1 0 2 2 2 0 Bd3614-like deaminase STAT1_TAZ2bind PF12162.8 GAX24541.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain RPAP1_N PF08621.10 GAX24542.1 - 0.81 9.5 13.3 5.1 6.9 2.9 2.9 2 0 0 2 2 2 0 RPAP1-like, N-terminal Sigma70_r2 PF04542.14 GAX24543.1 - 2.2e-16 59.4 0.0 6.3e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 GAX24543.1 - 2.8e-14 52.9 0.1 2.6e-13 49.8 0.1 2.6 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 GAX24543.1 - 1.1e-07 31.2 0.7 6.8e-07 28.7 0.3 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 GAX24543.1 - 0.019 14.6 1.7 5.1 6.9 0.0 3.4 2 1 0 2 2 2 0 Sigma-70, region 4 APO_RNA-bind PF05634.11 GAX24543.1 - 0.021 14.2 0.1 0.051 12.9 0.1 1.6 1 0 0 1 1 1 0 APO RNA-binding Pkinase PF00069.25 GAX24544.1 - 2e-59 201.1 0.0 2.3e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24544.1 - 3.8e-46 157.5 0.0 4.5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX24544.1 - 1.6e-05 24.3 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX24544.1 - 4e-05 23.1 0.0 0.00038 19.9 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAX24544.1 - 0.00072 18.4 0.1 0.00092 18.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX24544.1 - 0.0034 17.3 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX24544.1 - 0.0053 15.8 0.1 0.008 15.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 GAX24544.1 - 0.032 13.8 0.1 0.13 11.8 0.0 1.7 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 GAX24544.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 SET PF00856.28 GAX24545.1 - 4.4e-05 23.9 0.1 0.019 15.3 0.0 3.4 2 1 0 2 2 2 2 SET domain CopG_antitoxin PF12441.8 GAX24546.1 - 0.099 13.2 0.4 3.6 8.2 0.0 3.3 4 0 0 4 4 4 0 CopG antitoxin of type II toxin-antitoxin system Sulfotransfer_4 PF17784.1 GAX24547.1 - 4.6e-43 147.6 0.0 6.5e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX24547.1 - 0.0057 17.1 0.0 0.021 15.2 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family AAA PF00004.29 GAX24548.1 - 1.3e-50 171.2 0.0 1.9e-39 135.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 GAX24548.1 - 1.1e-14 54.6 0.3 6.4e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal IstB_IS21 PF01695.17 GAX24548.1 - 9.2e-08 32.0 0.0 0.02 14.6 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_16 PF13191.6 GAX24548.1 - 1.5e-07 32.0 0.4 0.038 14.4 0.1 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 GAX24548.1 - 6.9e-07 29.3 0.0 0.025 14.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX24548.1 - 1.1e-06 29.0 1.1 0.025 14.8 0.0 3.8 3 1 1 4 4 3 2 AAA domain AAA_2 PF07724.14 GAX24548.1 - 4.2e-06 27.0 0.0 0.024 14.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 GAX24548.1 - 4.8e-05 23.2 0.0 0.023 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAX24548.1 - 5e-05 23.8 0.2 0.04 14.4 0.0 3.3 2 1 0 3 3 3 1 ABC transporter RuvB_N PF05496.12 GAX24548.1 - 0.00025 20.8 0.0 0.0038 17.0 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 GAX24548.1 - 0.00041 19.7 0.0 0.33 10.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 GAX24548.1 - 0.00074 19.7 0.0 0.061 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX24548.1 - 0.00082 19.3 0.7 0.11 12.4 0.1 3.6 2 2 1 3 3 3 1 NACHT domain AAA_18 PF13238.6 GAX24548.1 - 0.001 19.6 0.0 0.024 15.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 GAX24548.1 - 0.0019 18.5 0.7 3.7 8.0 0.0 3.1 2 1 0 2 2 2 1 RNA helicase PhoH PF02562.16 GAX24548.1 - 0.0029 17.1 0.3 0.66 9.4 0.1 2.7 2 1 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 GAX24548.1 - 0.0034 17.6 0.1 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAX24548.1 - 0.0037 17.0 0.0 3.6 7.4 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain TsaE PF02367.17 GAX24548.1 - 0.0047 16.9 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 GAX24548.1 - 0.0097 15.7 0.1 0.7 9.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 GAX24548.1 - 0.012 15.4 0.0 2.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.6 GAX24548.1 - 0.013 15.1 1.3 13 5.3 0.0 3.7 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GAX24548.1 - 0.015 14.8 0.0 0.39 10.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 GAX24548.1 - 0.02 14.8 0.0 0.061 13.2 0.0 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain RNA12 PF10443.9 GAX24548.1 - 0.032 13.0 0.1 0.098 11.4 0.0 1.8 2 0 0 2 2 2 0 RNA12 protein ATPase_2 PF01637.18 GAX24548.1 - 0.035 14.0 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 GAX24548.1 - 0.048 13.0 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 KaiC Bac_DnaA PF00308.18 GAX24548.1 - 0.049 13.5 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein TIP49 PF06068.13 GAX24548.1 - 0.051 12.8 0.0 0.84 8.8 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain DEAD PF00270.29 GAX24548.1 - 0.057 13.2 0.0 0.33 10.7 0.0 2.3 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_23 PF13476.6 GAX24548.1 - 0.089 13.3 0.1 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAX24548.1 - 0.093 13.1 0.1 3.2 8.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 GAX24548.1 - 0.1 12.5 0.5 24 4.8 0.0 3.3 3 0 0 3 3 3 0 NTPase ResIII PF04851.15 GAX24548.1 - 0.1 12.6 0.0 6.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 GAX24548.1 - 0.21 10.8 0.1 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CBM_6 PF03422.15 GAX24549.1 - 7.6e-33 113.5 3.7 4.5e-20 72.2 1.6 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX24549.1 - 5.1e-14 52.4 2.0 9.3e-14 51.5 2.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX24549.1 - 3.7e-10 39.9 1.5 1.2e-05 25.4 0.8 2.4 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX24549.1 - 0.011 16.0 0.9 0.04 14.2 0.4 2.0 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) CopC PF04234.12 GAX24549.1 - 0.013 16.5 0.1 2.9 9.0 0.0 2.4 2 0 0 2 2 2 0 CopC domain DUF5011 PF16403.5 GAX24549.1 - 0.041 14.0 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) MAM PF00629.23 GAX24549.1 - 0.18 11.7 0.5 2.7 7.9 0.1 2.6 3 0 0 3 3 3 0 MAM domain, meprin/A5/mu AAA PF00004.29 GAX24550.1 - 4.9e-37 127.3 0.0 1.4e-36 125.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAX24550.1 - 7.7e-08 32.2 0.5 1.1e-06 28.5 0.0 3.1 4 0 0 4 4 4 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 GAX24550.1 - 1.8e-06 27.6 0.0 0.00012 21.8 0.0 2.7 1 1 1 2 2 2 1 AAA+ lid domain DUF815 PF05673.13 GAX24550.1 - 8.6e-06 25.1 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAX24550.1 - 1.1e-05 25.7 1.0 0.00024 21.4 0.1 3.3 2 2 1 3 3 2 1 AAA domain AAA_16 PF13191.6 GAX24550.1 - 4.4e-05 23.9 2.2 0.00015 22.2 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAX24550.1 - 5.4e-05 23.0 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain MIT PF04212.18 GAX24550.1 - 0.00022 21.2 0.9 0.00058 19.9 0.2 2.2 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_5 PF07728.14 GAX24550.1 - 0.00027 21.0 0.0 0.0013 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 GAX24550.1 - 0.00051 20.1 0.1 0.0022 18.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MCM PF00493.23 GAX24550.1 - 0.00099 18.3 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain IstB_IS21 PF01695.17 GAX24550.1 - 0.001 18.9 0.0 0.0032 17.2 0.0 1.8 1 1 1 2 2 2 1 IstB-like ATP binding protein TniB PF05621.11 GAX24550.1 - 0.0011 18.4 0.0 0.055 12.9 0.0 2.5 1 1 1 2 2 2 1 Bacterial TniB protein AAA_2 PF07724.14 GAX24550.1 - 0.0011 19.1 0.0 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 GAX24550.1 - 0.0058 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 GAX24550.1 - 0.0059 16.9 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAX24550.1 - 0.0061 16.1 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 GAX24550.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAX24550.1 - 0.011 15.6 0.0 0.011 15.6 0.0 2.7 2 1 0 2 2 1 0 AAA domain ATPase PF06745.13 GAX24550.1 - 0.012 15.0 0.0 0.095 12.0 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.6 GAX24550.1 - 0.014 15.9 0.0 0.05 14.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 GAX24550.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.3 1 1 0 2 2 2 0 NACHT domain TIP49 PF06068.13 GAX24550.1 - 0.021 14.0 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 GAX24550.1 - 0.023 14.9 0.4 0.075 13.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 GAX24550.1 - 0.027 14.7 0.1 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAX24550.1 - 0.03 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 GAX24550.1 - 0.03 13.6 0.2 0.21 10.8 0.0 2.4 3 0 0 3 3 2 0 Zeta toxin AAA_14 PF13173.6 GAX24550.1 - 0.036 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX24550.1 - 0.047 13.4 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAX24550.1 - 0.075 12.6 0.1 0.4 10.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAX24550.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 GAX24550.1 - 0.14 12.7 0.7 0.29 11.7 0.0 2.0 2 1 0 2 2 1 0 ABC transporter RNA_helicase PF00910.22 GAX24550.1 - 0.16 12.3 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NUDIX PF00293.28 GAX24551.1 - 5.6e-10 39.4 0.1 8.6e-09 35.5 0.0 2.4 2 1 0 2 2 2 1 NUDIX domain adh_short PF00106.25 GAX24552.1 - 5.1e-29 101.1 0.3 1.5e-25 89.9 0.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX24552.1 - 1e-15 58.0 0.4 4.3e-15 55.9 0.2 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX24552.1 - 9.6e-06 25.6 0.1 1.7e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX24552.1 - 0.00026 20.6 0.1 0.00064 19.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX24552.1 - 0.0014 18.6 0.1 0.0023 17.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 GAX24552.1 - 0.0039 17.2 0.1 0.011 15.8 0.0 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 GAX24552.1 - 0.047 13.9 0.1 0.096 12.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain RPN7 PF10602.9 GAX24553.1 - 2.1e-20 73.2 4.4 5.6e-20 71.7 4.4 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAX24553.1 - 3.1e-06 27.6 0.3 1.2e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain Astro_capsid_N PF03115.14 GAX24553.1 - 0.06 12.0 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Lactamase_B_2 PF12706.7 GAX24554.1 - 5.2e-21 75.1 0.1 1.3e-19 70.5 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX24554.1 - 5e-05 23.4 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Cation_ATPase_C PF00689.21 GAX24555.1 - 1e-38 132.9 6.5 2.5e-38 131.6 6.5 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAX24555.1 - 1.2e-35 122.6 0.8 1.2e-35 122.6 0.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAX24555.1 - 9.5e-17 60.9 0.0 2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAX24555.1 - 2.8e-15 57.2 2.1 2.3e-09 37.9 0.1 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX24555.1 - 1.8e-10 40.3 0.0 5.6e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX24555.1 - 8.7e-05 22.4 1.1 0.00079 19.2 0.4 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase RibD_C PF01872.17 GAX24556.1 - 8.5e-19 68.2 0.0 1.6e-18 67.3 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 GAX24556.1 - 0.00017 21.3 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Cation_ATPase_C PF00689.21 GAX24557.1 - 1e-39 136.2 4.2 2.3e-39 135.0 4.2 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAX24557.1 - 2.7e-36 124.8 0.7 2.7e-36 124.8 0.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAX24557.1 - 4.4e-17 61.9 0.0 8.9e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAX24557.1 - 5.1e-15 56.3 1.9 4e-09 37.1 0.1 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX24557.1 - 1.1e-10 41.1 0.0 3.3e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX24557.1 - 9e-05 22.3 1.0 0.00076 19.3 0.4 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase F_bP_aldolase PF01116.20 GAX24558.1 - 3e-92 309.0 0.0 3.5e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ABC_sub_bind PF04392.12 GAX24558.1 - 0.12 11.6 0.1 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter substrate binding protein Lipase_GDSL_2 PF13472.6 GAX24558.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DsbD PF02683.15 GAX24559.1 - 7.5e-32 111.0 9.1 3.3e-31 108.9 9.1 1.9 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 GAX24559.1 - 9.2e-10 38.8 13.8 1e-09 38.7 12.7 1.7 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Trypsin PF00089.26 GAX24560.1 - 4.9e-38 131.2 0.0 8e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Bestrophin PF01062.21 GAX24561.1 - 4.4e-35 121.5 0.5 6.5e-35 121.0 0.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PPV_E1_N PF00524.18 GAX24561.1 - 0.02 15.3 0.2 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 E1 Protein, N terminal domain Mito_carr PF00153.27 GAX24562.1 - 9.2e-36 121.7 0.2 1.3e-16 60.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein BCLP PF12304.8 GAX24562.1 - 0.074 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Beta-casein like protein Methyltransf_16 PF10294.9 GAX24563.1 - 9.9e-18 64.5 0.1 5.3e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase GidB PF02527.15 GAX24563.1 - 0.054 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 GAX24563.1 - 0.054 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAX24563.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain tRNA-synt_1g PF09334.11 GAX24564.1 - 6.2e-111 370.9 0.3 2.7e-65 220.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAX24564.1 - 3e-29 101.8 1.5 7.2e-16 57.6 0.0 3.6 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 GAX24564.1 - 1.1e-18 67.7 0.1 6.5e-11 42.1 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain zf-RING_2 PF13639.6 GAX24565.1 - 3.1e-12 46.6 7.2 3.1e-12 46.6 7.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GAX24565.1 - 1.3e-09 37.6 1.7 3e-09 36.4 1.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX24565.1 - 8.6e-09 35.1 7.7 1.8e-08 34.0 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX24565.1 - 1e-06 28.5 5.5 2.8e-06 27.1 5.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX24565.1 - 2.1e-06 27.9 11.7 2.3e-05 24.6 11.7 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX24565.1 - 8.1e-05 22.6 4.2 0.0001 22.3 2.2 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX24565.1 - 8.3e-05 22.5 4.9 8.3e-05 22.5 4.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.8 GAX24565.1 - 0.00053 20.1 4.8 0.0031 17.7 4.9 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAX24565.1 - 0.0015 18.4 3.7 0.0043 16.9 3.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 GAX24565.1 - 0.0045 17.3 4.5 0.013 15.8 4.5 1.8 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 GAX24565.1 - 0.0052 16.8 5.2 0.016 15.2 5.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX24565.1 - 0.0092 15.6 3.8 0.025 14.2 3.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX24565.1 - 0.5 10.3 10.5 4.5 7.2 9.9 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 RINGv PF12906.7 GAX24565.1 - 1.3 9.2 10.1 1 9.5 6.7 2.6 2 1 0 2 2 2 0 RING-variant domain Inositol_P PF00459.25 GAX24566.1 - 1.1e-51 176.0 0.2 1.3e-51 175.7 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 GAX24566.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Glutaredoxin PF00462.24 GAX24567.1 - 3.8e-16 59.1 0.0 6.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 GAX24567.1 - 0.0028 17.9 0.0 0.0045 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAX24567.1 - 0.0047 17.3 0.0 0.0073 16.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DnaJ PF00226.31 GAX24568.1 - 9.5e-19 67.3 2.6 2.2e-18 66.1 1.0 2.5 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 GAX24568.1 - 1.4e-17 63.6 0.2 5.8e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX24568.1 - 1.3e-11 44.6 1.2 2e-05 24.8 0.1 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain RAC_head PF16717.5 GAX24568.1 - 8.8e-08 33.0 4.4 8.8e-08 33.0 4.4 3.1 2 0 0 2 2 2 1 Ribosome-associated complex head domain Nop53 PF07767.11 GAX24568.1 - 0.0036 16.7 28.9 0.0036 16.7 28.9 2.8 2 1 1 3 3 3 1 Nop53 (60S ribosomal biogenesis) MMR_HSR1 PF01926.23 GAX24569.1 - 7.4e-19 67.9 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX24569.1 - 2.2e-06 27.7 0.0 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAX24569.1 - 3.9e-06 26.5 0.0 1.1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAX24569.1 - 8.4e-05 22.2 0.0 0.035 13.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 GAX24569.1 - 0.0018 18.5 0.0 0.0069 16.6 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 GAX24569.1 - 0.0023 16.9 0.0 0.0067 15.4 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAX24569.1 - 0.003 17.6 0.5 0.011 15.7 0.2 1.9 1 1 0 2 2 2 1 Dynamin family Septin PF00735.18 GAX24569.1 - 0.005 16.2 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Septin Ras PF00071.22 GAX24569.1 - 0.034 13.8 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Ras family ABC_tran PF00005.27 GAX24569.1 - 0.061 13.8 0.0 0.12 12.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAX24569.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 GAX24569.1 - 0.14 12.5 0.1 0.85 10.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Chloroa_b-bind PF00504.21 GAX24570.1 - 3e-05 24.6 0.0 4.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pkinase PF00069.25 GAX24571.1 - 1.3e-36 126.4 0.0 1.7e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24571.1 - 1.1e-27 96.9 0.0 1.7e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 GAX24571.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UQ_con PF00179.26 GAX24572.1 - 2.4e-41 140.7 0.0 2.8e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GTP_EFTU PF00009.27 GAX24573.1 - 1.3e-33 116.2 0.0 1.5e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAX24573.1 - 3.8e-05 23.7 0.0 0.00018 21.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAX24573.1 - 0.015 15.4 0.0 5.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Dynamin family NiFeSe_Hases PF00374.19 GAX24573.1 - 0.084 11.8 0.0 0.099 11.5 0.0 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase GTP_EFTU_D3 PF03143.17 GAX24574.1 - 3.1e-16 59.7 0.0 4.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAX24574.1 - 3.8e-09 36.8 0.6 7e-09 36.0 0.6 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAX24574.1 - 6.7e-07 29.1 2.3 2e-06 27.6 1.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Pkinase PF00069.25 GAX24575.1 - 4.4e-34 118.0 0.0 5.4e-24 85.0 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24575.1 - 3.9e-28 98.4 0.0 1.6e-27 96.5 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase 3H PF02829.14 GAX24575.1 - 0.051 13.9 0.2 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 3H domain FA_hydroxylase PF04116.13 GAX24578.1 - 1.4e-21 77.2 20.9 1.4e-21 77.2 20.9 2.1 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Thioredoxin PF00085.20 GAX24579.1 - 3.6e-12 46.2 0.0 5.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX24579.1 - 0.0009 19.5 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX24579.1 - 0.044 14.2 0.1 0.33 11.4 0.1 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain cNMP_binding PF00027.29 GAX24580.1 - 3.9e-16 58.9 0.0 1.1e-15 57.5 0.0 1.7 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Thioredoxin PF00085.20 GAX24580.1 - 7.7e-11 41.9 0.1 3.3e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin EF-hand_1 PF00036.32 GAX24580.1 - 1.3e-08 33.8 5.4 0.0001 21.6 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 GAX24580.1 - 2e-08 34.5 2.7 0.00048 20.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX24580.1 - 2.2e-07 30.3 2.0 0.039 13.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GAX24580.1 - 1.1e-06 27.9 1.9 0.00048 19.5 0.2 2.7 2 0 0 2 2 2 2 EF hand Thioredoxin_2 PF13098.6 GAX24580.1 - 0.019 15.4 0.2 0.3 11.6 0.2 2.5 1 1 0 1 1 1 0 Thioredoxin-like domain EF-hand_8 PF13833.6 GAX24580.1 - 1.7 8.5 4.9 16 5.5 0.1 3.4 4 1 1 5 5 5 0 EF-hand domain pair DUF3119 PF11317.8 GAX24581.1 - 7.4e-34 116.7 0.0 1e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) Transket_pyr PF02779.24 GAX24582.1 - 5.1e-65 218.5 0.0 8.8e-65 217.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 GAX24582.1 - 1.1e-59 201.8 0.0 2e-59 201.0 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 GAX24582.1 - 6.7e-52 175.2 0.0 1.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 GAX24582.1 - 4.9e-17 61.2 2.3 7.4e-17 60.7 0.6 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus DUF1451 PF07295.11 GAX24582.1 - 0.11 12.5 0.2 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain UT PF03253.14 GAX24584.1 - 2.3e-65 220.6 27.2 2.7e-65 220.4 27.2 1.0 1 0 0 1 1 1 1 Urea transporter DUF2407_C PF13373.6 GAX24586.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain CTP_transf_1 PF01148.20 GAX24587.1 - 6.4e-33 114.6 10.7 1.5e-32 113.5 10.7 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 GAX24587.1 - 0.00078 19.5 0.4 0.0015 18.6 0.0 1.6 2 0 0 2 2 2 1 CDP-archaeol synthase VP7 PF00434.18 GAX24587.1 - 0.029 13.5 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein VP7 Nucleoside_tran PF01733.18 GAX24588.1 - 1.6e-29 103.3 1.2 8.2e-26 91.1 0.1 2.5 2 0 0 2 2 2 2 Nucleoside transporter AIF_C PF14721.6 GAX24589.1 - 0.054 13.9 0.0 0.066 13.6 0.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term adh_short_C2 PF13561.6 GAX24590.1 - 6.2e-53 179.8 0.1 7.3e-53 179.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX24590.1 - 2.6e-08 33.6 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TPR_12 PF13424.6 GAX24591.1 - 9.5e-21 73.9 19.9 1.4e-09 38.1 0.6 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX24591.1 - 6.6e-17 60.8 26.4 8.9e-08 31.8 0.1 6.6 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24591.1 - 0.00037 20.2 8.4 0.033 14.0 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX24591.1 - 0.0044 17.0 17.9 0.012 15.7 0.2 5.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX24591.1 - 0.0044 16.7 0.3 0.56 9.9 0.1 3.3 2 1 0 2 2 2 1 TPR repeat DUF5344 PF17279.2 GAX24591.1 - 1 10.0 5.3 2.2 8.9 0.0 3.7 4 1 1 5 5 5 0 Family of unknown function (DUF5344) TPR_6 PF13174.6 GAX24591.1 - 2.2 9.1 10.5 25 5.8 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Dev_Cell_Death PF10539.9 GAX24592.1 - 1.5e-29 102.4 0.0 2.7e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Development and cell death domain zf-CCCH PF00642.24 GAX24592.1 - 2.3e-16 59.2 25.9 1.5e-09 37.6 3.6 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) YTH PF04146.15 GAX24592.1 - 8.3e-14 51.9 0.6 3.3e-13 49.9 0.6 2.0 1 1 0 1 1 1 1 YT521-B-like domain zf_CCCH_4 PF18345.1 GAX24592.1 - 2.4e-11 43.3 40.8 4.2e-06 26.6 4.4 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 GAX24592.1 - 1.4e-08 35.4 12.9 0.017 15.8 0.4 3.6 2 1 1 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 GAX24592.1 - 2.2e-07 30.5 7.8 1.1e-06 28.3 3.4 4.4 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAX24592.1 - 0.00052 20.4 37.1 0.0011 19.4 4.5 4.4 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 GAX24592.1 - 1.4 9.1 20.9 0.73 10.1 3.2 3.4 2 1 1 3 3 3 0 Zinc-finger containing family Peroxin-3 PF04882.12 GAX24593.1 - 3e-11 43.0 6.5 0.019 14.0 0.0 4.0 2 2 2 4 4 4 4 Peroxin-3 L27 PF02828.16 GAX24593.1 - 0.064 13.0 0.2 14 5.5 0.3 2.7 3 0 0 3 3 3 0 L27 domain DUF4453 PF14627.6 GAX24593.1 - 0.087 12.9 0.0 0.97 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4453) Glyco_hydro_38N PF01074.22 GAX24594.1 - 5.6e-92 308.2 6.3 8.2e-92 307.6 6.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 GAX24594.1 - 1.5e-19 69.9 0.1 5.7e-19 68.1 0.0 2.1 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 GAX24594.1 - 2.1e-15 57.4 0.0 4.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain FeoB_C PF07664.12 GAX24595.1 - 8.5 6.2 8.5 7.1 6.4 0.1 3.8 3 2 0 3 3 3 0 Ferrous iron transport protein B C terminus Shisa PF13908.6 GAX24596.1 - 0.31 11.3 2.3 0.37 11.0 0.1 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator PDZ PF00595.24 GAX24597.1 - 0.00027 21.2 0.0 0.00083 19.7 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Utp12 PF04003.12 GAX24599.1 - 5.2e-08 33.2 0.5 2.1e-07 31.2 0.4 2.1 2 0 0 2 2 2 1 Dip2/Utp12 Family AAA_11 PF13086.6 GAX24599.1 - 0.0021 17.9 0.5 0.0034 17.2 0.5 1.3 1 0 0 1 1 1 1 AAA domain PQQ_3 PF13570.6 GAX24599.1 - 0.12 12.9 0.1 0.42 11.2 0.1 1.9 1 0 0 1 1 1 0 PQQ-like domain BTV_NS2 PF04514.12 GAX24599.1 - 0.26 10.1 5.8 0.45 9.3 5.8 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Homoserine_dh PF00742.19 GAX24600.1 - 1.6e-51 174.6 0.0 3e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GAX24600.1 - 9.9e-15 55.2 0.0 1.8e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 GAX24600.1 - 0.00057 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain GFO_IDH_MocA PF01408.22 GAX24600.1 - 0.058 14.2 0.0 0.12 13.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PALP PF00291.25 GAX24601.1 - 7.8e-53 179.8 0.0 1.1e-52 179.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PDH PF02153.17 GAX24601.1 - 0.055 12.5 0.0 0.18 10.8 0.0 1.8 1 1 1 2 2 2 0 Prephenate dehydrogenase FdhD-NarQ PF02634.15 GAX24601.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 FdhD/NarQ family G-patch_2 PF12656.7 GAX24602.1 - 4e-15 55.6 0.1 4e-15 55.6 0.1 2.3 2 0 0 2 2 2 1 G-patch domain KN17_SH3 PF18131.1 GAX24602.1 - 4.6e-06 26.7 0.2 1.3e-05 25.2 0.1 1.8 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain PhdYeFM_antitox PF02604.19 GAX24602.1 - 0.05 13.4 0.2 0.22 11.3 0.2 2.2 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system His_Phos_1 PF00300.22 GAX24604.1 - 7.3e-27 94.3 0.0 2.6e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) zinc_ribbon_16 PF17034.5 GAX24605.1 - 7.5e-24 84.3 13.3 3.1e-23 82.3 13.3 2.1 1 1 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 GAX24605.1 - 0.0028 17.3 8.6 0.0028 17.3 8.6 2.5 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type Pex26 PF07163.12 GAX24605.1 - 0.028 13.7 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Pex26 protein AAA PF00004.29 GAX24606.1 - 2.3e-37 128.4 0.0 4.3e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX24606.1 - 9e-14 51.0 0.0 1.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAX24606.1 - 1.1e-05 25.7 0.1 5.6e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX24606.1 - 1.4e-05 25.6 0.6 0.0011 19.4 0.1 2.8 1 1 2 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAX24606.1 - 2.4e-05 24.4 1.5 0.00019 21.4 1.5 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX24606.1 - 4.2e-05 23.3 0.1 0.011 15.5 0.0 3.3 3 1 1 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX24606.1 - 0.0016 18.6 0.3 0.019 15.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAX24606.1 - 0.0019 18.3 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Torsin PF06309.11 GAX24606.1 - 0.0027 17.8 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 Torsin NACHT PF05729.12 GAX24606.1 - 0.0048 16.8 0.2 0.026 14.4 0.2 2.1 1 1 0 1 1 1 1 NACHT domain TIP49 PF06068.13 GAX24606.1 - 0.0069 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 GAX24606.1 - 0.0098 16.4 0.0 0.029 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAX24606.1 - 0.0098 15.5 0.4 1.5 8.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 GAX24606.1 - 0.011 15.1 0.3 0.033 13.6 0.2 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX24606.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 GAX24606.1 - 0.028 14.4 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 GAX24606.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 GAX24606.1 - 0.032 14.1 0.0 0.085 12.7 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 GAX24606.1 - 0.046 13.0 0.4 0.099 11.9 0.4 1.7 1 1 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 GAX24606.1 - 0.053 13.2 0.3 0.69 9.6 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 GAX24606.1 - 0.055 13.9 0.1 0.19 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF2791 PF10923.8 GAX24606.1 - 0.15 10.8 1.2 0.42 9.4 0.1 2.1 3 0 0 3 3 3 0 P-loop Domain of unknown function (DUF2791) Ank_4 PF13637.6 GAX24607.1 - 5.4e-12 46.0 0.3 2.9e-11 43.6 0.1 2.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX24607.1 - 9.5e-12 44.9 0.6 1.5e-08 34.7 0.2 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX24607.1 - 4.9e-11 43.1 0.0 1.1e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX24607.1 - 1.5e-09 37.3 0.1 4.4e-06 26.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAX24607.1 - 3e-05 24.2 0.0 0.00016 22.0 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Macro PF01661.21 GAX24608.1 - 6.5e-26 90.7 0.0 9.6e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Macro domain OMPdecase PF00215.24 GAX24609.1 - 5e-32 111.3 0.0 6.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family LrgB PF04172.16 GAX24610.1 - 6.7e-42 143.4 14.3 6.7e-42 143.4 14.3 2.2 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 GAX24610.1 - 0.00058 19.8 1.6 0.00058 19.8 1.6 3.8 4 0 0 4 4 4 2 LrgA family TRAM_LAG1_CLN8 PF03798.16 GAX24610.1 - 7.3 6.3 7.4 7.7 6.2 0.4 2.6 2 0 0 2 2 2 0 TLC domain DUF568 PF04526.13 GAX24611.1 - 0.14 12.9 1.3 27 5.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF568) TBCC PF07986.12 GAX24612.1 - 5.8e-18 64.8 0.1 1.3e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C VPS53_C PF16854.5 GAX24612.1 - 0.21 11.4 1.4 0.33 10.8 0.7 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus VPS38 PF17649.1 GAX24612.1 - 1.7 7.4 7.3 0.5 9.2 4.1 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting 38 CCDC-167 PF15188.6 GAX24612.1 - 7.8 6.9 11.9 2 8.8 6.2 2.7 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 HATPase_c PF02518.26 GAX24613.1 - 1.1e-21 77.5 0.0 3.1e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX24613.1 - 3.8e-14 52.8 0.0 1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAX24613.1 - 2.6e-07 30.6 0.0 1.1e-05 25.3 0.0 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF4736 PF15883.5 GAX24613.1 - 0.14 11.8 1.5 0.37 10.5 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) NAD_binding_8 PF13450.6 GAX24614.1 - 6e-11 42.4 0.2 1.3e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX24614.1 - 5e-10 39.0 0.5 2.5e-05 23.6 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 GAX24614.1 - 4.7e-08 33.0 0.0 0.0004 20.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAX24614.1 - 5.9e-07 29.1 0.2 0.0015 17.9 0.0 2.8 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAX24614.1 - 0.0011 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX24614.1 - 0.0018 17.6 0.0 0.0038 16.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 GAX24614.1 - 0.002 17.5 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 GAX24614.1 - 0.0035 16.8 0.1 0.077 12.4 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.22 GAX24614.1 - 0.0039 16.3 0.1 0.0067 15.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAX24614.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX24614.1 - 0.026 13.2 0.0 0.051 12.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAX24614.1 - 0.073 12.3 0.1 0.23 10.7 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 GAX24614.1 - 0.15 10.6 0.0 3.1 6.2 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor HEAT PF02985.22 GAX24615.1 - 0.01 16.0 1.9 6.3 7.3 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 GAX24615.1 - 0.012 16.0 0.5 24 5.4 0.0 4.3 4 1 0 4 4 4 0 HEAT repeats Cnd1 PF12717.7 GAX24615.1 - 0.024 14.7 0.7 0.07 13.2 0.7 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Choline_kin_N PF04428.14 GAX24615.1 - 0.12 12.1 0.0 4.8 6.9 0.0 2.9 2 0 0 2 2 2 0 Choline kinase N terminus PROCN PF08083.11 GAX24616.1 - 2.2e-230 764.4 8.8 3.3e-230 763.8 8.8 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 GAX24616.1 - 1.9e-128 426.8 0.4 3.3e-128 426.1 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 GAX24616.1 - 2.5e-87 290.8 2.6 7.5e-87 289.2 2.6 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 GAX24616.1 - 2.9e-75 251.3 1.8 1.1e-74 249.5 1.8 2.1 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 GAX24616.1 - 4.6e-71 237.1 0.0 9.5e-71 236.1 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 GAX24616.1 - 9.6e-48 160.5 0.2 2.8e-47 159.0 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 GAX24616.1 - 1.9e-44 150.5 0.0 5.6e-44 149.0 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 GAX24616.1 - 0.00019 21.4 0.0 0.00061 19.7 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HA PF03457.14 GAX24617.1 - 1.7e-48 162.7 10.4 2.2e-21 75.9 2.7 3.2 3 0 0 3 3 3 3 Helicase associated domain DUF2153 PF09921.9 GAX24617.1 - 0.075 12.8 1.1 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) NAD_binding_10 PF13460.6 GAX24618.1 - 1.6e-10 41.2 0.1 1.6e-10 41.2 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAX24618.1 - 1.5e-07 31.1 0.9 3e-07 30.1 0.6 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX24618.1 - 0.00015 21.0 0.2 0.00022 20.4 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 GAX24618.1 - 0.0012 18.5 3.2 0.0058 16.2 3.0 2.1 1 1 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.19 GAX24618.1 - 0.012 15.0 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAX24618.1 - 0.012 15.0 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAX24618.1 - 0.029 13.4 0.1 0.046 12.7 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FA_hydroxylase PF04116.13 GAX24619.1 - 3.3e-18 66.3 10.7 3.3e-18 66.3 10.7 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GTP-bdg_N PF13167.6 GAX24620.1 - 7.5e-31 106.7 0.3 1.7e-30 105.5 0.3 1.7 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 GAX24620.1 - 2.8e-29 101.5 2.4 5.9e-29 100.5 2.4 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 GAX24620.1 - 4.5e-21 75.1 0.1 2.3e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX24620.1 - 9e-07 28.9 0.9 0.036 14.0 0.4 2.6 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAX24620.1 - 4.6e-05 23.0 0.3 0.00013 21.5 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX24620.1 - 0.00032 20.8 2.4 0.076 13.1 0.0 3.3 3 1 1 4 4 4 2 Dynamin family cobW PF02492.19 GAX24620.1 - 0.0012 18.4 1.5 0.04 13.5 0.2 2.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 GAX24620.1 - 0.0042 16.6 0.1 0.06 12.9 0.4 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 GAX24620.1 - 0.011 15.7 0.2 0.043 13.8 0.1 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Arf PF00025.21 GAX24620.1 - 0.02 14.3 0.8 0.29 10.6 0.8 2.3 1 1 0 1 1 1 0 ADP-ribosylation factor family HOOK PF05622.12 GAX24620.1 - 0.082 11.1 1.9 0.97 7.5 0.1 2.2 2 0 0 2 2 2 0 HOOK protein Helicase_C PF00271.31 GAX24620.1 - 0.16 12.3 0.3 0.92 9.9 0.0 2.3 3 0 0 3 3 3 0 Helicase conserved C-terminal domain CDC37_C PF08564.10 GAX24620.1 - 0.51 10.5 2.3 3.4 7.8 0.1 3.0 3 0 0 3 3 3 0 Cdc37 C terminal domain Ank_4 PF13637.6 GAX24621.1 - 1e-05 26.0 0.0 2.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX24621.1 - 4.2e-05 24.1 0.0 8.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX24621.1 - 0.0012 19.2 0.0 0.0037 17.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat LON_substr_bdg PF02190.16 GAX24622.1 - 0.0011 18.8 3.3 0.0073 16.2 0.1 2.8 2 2 1 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain SchA_CurD PF04486.12 GAX24622.1 - 0.085 13.0 0.3 0.72 10.0 0.0 2.4 2 1 1 3 3 3 0 SchA/CurD like domain Syntaxin_2 PF14523.6 GAX24622.1 - 0.69 10.3 3.7 0.46 10.9 0.3 2.3 3 0 0 3 3 3 0 Syntaxin-like protein Toprim_N PF08275.11 GAX24623.1 - 1.5e-22 80.0 0.0 7.9e-21 74.4 0.0 2.7 1 1 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 GAX24623.1 - 1.1e-17 63.7 0.4 2.6e-17 62.4 0.4 1.6 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_2 PF13155.6 GAX24623.1 - 1.7e-13 50.8 0.0 5.4e-13 49.2 0.0 2.0 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 GAX24623.1 - 2e-11 44.2 0.0 6.1e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 GAX24623.1 - 7e-05 23.1 0.0 0.00026 21.3 0.0 2.0 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.22 GAX24623.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Toprim domain 3HCDH_N PF02737.18 GAX24624.1 - 7.9e-52 175.8 0.1 1.9e-51 174.5 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 GAX24624.1 - 1.5e-40 139.1 0.0 2.5e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 GAX24624.1 - 1.5e-31 108.8 0.1 1.4e-23 83.3 0.0 3.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 GAX24624.1 - 1.2e-18 67.7 0.0 4.2e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase RelE PF06296.12 GAX24624.1 - 0.034 14.3 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system SR-25 PF10500.9 GAX24624.1 - 0.87 9.1 9.5 1.9 8.0 9.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 GAX24625.1 - 4.3e-136 455.5 71.3 4.3e-136 455.5 71.3 1.3 1 1 0 1 1 1 1 Utp14 protein Synaptobrevin PF00957.21 GAX24626.1 - 9.3e-26 89.5 2.9 1.5e-25 88.7 2.9 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAX24626.1 - 8.1e-05 22.6 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1860 PF08949.10 GAX24626.1 - 0.018 14.8 1.0 0.022 14.5 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) Fzo_mitofusin PF04799.13 GAX24626.1 - 0.038 13.5 2.3 0.061 12.9 2.3 1.4 1 0 0 1 1 1 0 fzo-like conserved region Orf78 PF06024.12 GAX24626.1 - 0.096 13.0 1.0 0.19 12.1 1.0 1.6 1 1 0 1 1 1 0 Orf78 (ac78) DHR10 PF18595.1 GAX24626.1 - 0.11 12.6 5.6 0.28 11.3 5.6 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain zf-trcl PF13451.6 GAX24627.1 - 0.032 14.1 0.8 0.068 13.1 0.8 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-CCHC PF00098.23 GAX24627.1 - 7.8 6.8 7.1 5.2 7.3 1.0 2.5 2 0 0 2 2 2 0 Zinc knuckle ClpS PF02617.17 GAX24628.1 - 5.9e-14 51.6 0.3 9.6e-14 50.9 0.3 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS PGM_PMM_I PF02878.16 GAX24629.1 - 7.4e-30 103.5 0.0 1.4e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 GAX24629.1 - 5.6e-22 78.3 0.0 1.9e-21 76.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAX24629.1 - 2.9e-13 50.0 0.0 6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 GAX24629.1 - 0.00027 21.1 0.0 0.00071 19.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain polyprenyl_synt PF00348.17 GAX24630.1 - 5.2e-63 212.5 0.0 6.7e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1815 PF08844.10 GAX24631.1 - 0.064 13.2 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) BT1 PF03092.16 GAX24632.1 - 1e-40 139.5 11.8 6.1e-24 84.1 7.9 3.1 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 GAX24632.1 - 1.2e-05 24.5 0.0 4.5e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 PUCC protein FHA PF00498.26 GAX24633.1 - 2.5e-09 37.3 0.0 8.8e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 FHA domain WD40 PF00400.32 GAX24634.1 - 1.4e-07 32.1 1.0 0.0014 19.4 0.2 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAX24634.1 - 0.00036 19.6 0.3 0.037 13.0 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 GAX24634.1 - 0.00053 20.2 0.1 0.044 14.1 0.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 GAX24637.1 - 5.6e-63 212.8 0.0 6.5e-62 209.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24637.1 - 1.5e-31 109.6 0.0 1.7e-24 86.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX24637.1 - 7.4e-07 28.4 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 GAX24637.1 - 0.0034 17.0 0.1 0.0063 16.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAX24637.1 - 0.006 16.5 0.2 0.19 11.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX24637.1 - 0.12 11.7 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX24637.1 - 0.2 10.9 0.0 0.68 9.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Mhr1 PF12829.7 GAX24637.1 - 0.3 11.2 0.8 3.6 7.7 0.1 2.5 3 0 0 3 3 3 0 Transcriptional regulation of mitochondrial recombination PDZ PF00595.24 GAX24638.1 - 0.0051 17.1 0.1 0.01 16.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX24638.1 - 0.032 14.1 0.1 0.083 12.7 0.1 1.7 1 0 0 1 1 1 0 PDZ domain Pro_isomerase PF00160.21 GAX24639.1 - 9.3e-05 22.7 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CENP-H PF05837.12 GAX24639.1 - 1 9.8 4.5 1.6 9.2 4.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ANAPC10 PF03256.16 GAX24640.1 - 0.042 13.5 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Snapin_Pallidin PF14712.6 GAX24640.1 - 0.1 13.1 3.3 0.15 12.5 3.3 1.2 1 0 0 1 1 1 0 Snapin/Pallidin PA28_beta PF02252.18 GAX24641.1 - 8.1e-22 77.5 0.2 6.5e-17 61.6 0.0 2.4 3 0 0 3 3 3 2 Proteasome activator pa28 beta subunit RepB_primase PF16793.5 GAX24641.1 - 0.01 16.0 3.8 0.026 14.6 0.3 2.1 2 0 0 2 2 2 0 RepB DNA-primase from phage plasmid DASH_Dad2 PF08654.10 GAX24641.1 - 0.09 13.2 2.2 14 6.2 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad2 SNARE PF05739.19 GAX24641.1 - 0.14 12.2 1.8 8.5 6.5 0.0 2.4 2 0 0 2 2 2 0 SNARE domain DUF883 PF05957.13 GAX24641.1 - 1.1 9.9 4.4 19 5.9 0.1 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) LRR_4 PF12799.7 GAX24642.1 - 6.1e-16 58.3 16.1 0.00021 21.6 4.0 6.9 5 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX24642.1 - 9.9e-14 50.9 42.7 2.8e-08 33.4 11.6 5.3 4 2 3 7 7 7 4 Leucine rich repeat LRR_1 PF00560.33 GAX24642.1 - 2.9e-06 27.1 10.4 0.078 13.6 0.7 6.4 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX24642.1 - 0.017 15.1 18.0 0.59 10.3 1.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.6 GAX24642.1 - 0.2 11.1 0.6 0.49 9.9 0.6 1.6 1 0 0 1 1 1 0 Leucine-rich repeat DUF150_C PF17384.2 GAX24643.1 - 3.8e-05 23.7 0.0 9.9e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 RimP C-terminal SH3 domain Pkinase PF00069.25 GAX24644.1 - 1.6e-40 139.2 0.0 6.5e-40 137.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24644.1 - 3.1e-21 75.8 0.0 2.9e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX24644.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GAX24644.1 - 0.0079 15.8 0.9 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 GAX24644.1 - 0.011 15.7 0.7 0.044 13.7 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Rcd1 PF04078.13 GAX24645.1 - 4.5e-126 419.4 0.5 5.2e-126 419.2 0.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RRM_1 PF00076.22 GAX24646.1 - 3.3e-71 235.0 0.4 9e-21 73.5 0.0 6.0 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAX24646.1 - 1.6e-05 24.8 0.1 0.00064 19.7 0.1 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 GAX24646.1 - 6.3e-05 23.0 0.2 2.9 8.0 0.0 5.4 5 0 0 5 5 5 1 Limkain b1 RRM_5 PF13893.6 GAX24646.1 - 0.00013 21.6 0.0 0.045 13.3 0.0 4.0 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAX24646.1 - 0.0003 20.6 0.0 2.7 7.9 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif BRAP2 PF07576.12 GAX24646.1 - 0.0011 19.1 0.1 0.36 11.1 0.0 3.4 3 0 0 3 3 3 1 BRCA1-associated protein 2 RRM_Rrp7 PF17799.1 GAX24646.1 - 0.026 14.3 3.1 3 7.6 0.0 4.4 5 0 0 5 5 5 0 Rrp7 RRM-like N-terminal domain BCDHK_Adom3 PF10436.9 GAX24646.1 - 0.12 12.1 0.9 0.26 11.1 0.9 1.4 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF4789 PF16033.5 GAX24646.1 - 0.17 12.4 5.7 1.2 9.7 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4789) OB_RNB PF08206.11 GAX24646.1 - 0.18 11.5 0.4 25 4.7 0.1 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain PIG-P PF08510.12 GAX24647.1 - 0.031 14.2 0.5 0.062 13.2 0.5 1.4 1 0 0 1 1 1 0 PIG-P BCDHK_Adom3 PF10436.9 GAX24648.1 - 1.6e-41 141.9 0.3 2.1e-41 141.5 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAX24648.1 - 1e-11 45.3 0.0 3.3e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX24648.1 - 0.0044 16.9 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SQS_PSY PF00494.19 GAX24649.1 - 1.4e-36 126.4 0.0 2.8e-36 125.4 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase NUDIX PF00293.28 GAX24649.1 - 3.6e-19 69.1 0.0 7.7e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Vinculin PF01044.19 GAX24649.1 - 0.033 12.5 0.0 0.051 11.8 0.0 1.2 1 0 0 1 1 1 0 Vinculin family FAD_binding_8 PF08022.12 GAX24650.1 - 1.9e-18 66.6 0.0 5.1e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 GAX24650.1 - 2.4e-18 66.5 4.6 4.4e-18 65.6 4.6 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAX24650.1 - 1e-10 41.9 0.0 0.00027 21.1 0.0 2.7 2 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 GAX24650.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain BTB_2 PF02214.22 GAX24652.1 - 7.4e-09 35.8 0.0 1.8e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF4596 PF15363.6 GAX24652.1 - 0.47 10.7 3.1 1.4 9.2 3.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) ANAPC4_WD40 PF12894.7 GAX24653.1 - 1.3e-06 28.6 0.0 0.46 10.8 0.0 3.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX24653.1 - 5.7e-06 27.0 6.3 0.33 11.9 0.0 6.5 8 0 0 8 8 8 2 WD domain, G-beta repeat PQQ_3 PF13570.6 GAX24653.1 - 0.028 14.9 0.6 8.7 7.0 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.21 GAX24653.1 - 0.097 12.6 1.0 18 5.5 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat PseudoU_synth_1 PF01416.20 GAX24654.1 - 2.2e-20 73.1 0.1 7.2e-19 68.2 0.1 2.4 2 1 0 2 2 2 1 tRNA pseudouridine synthase Inhibitor_I9 PF05922.16 GAX24654.1 - 0.0027 18.3 0.3 1.2 9.9 0.0 2.4 1 1 1 2 2 2 2 Peptidase inhibitor I9 Methyltransf_21 PF05050.12 GAX24655.1 - 1.8e-10 41.1 0.0 2.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 GAX24656.1 - 5.2e-10 39.6 0.0 8.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain GSHPx PF00255.19 GAX24657.1 - 6e-34 115.9 0.7 1.2e-33 114.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione peroxidase ShK PF01549.24 GAX24657.1 - 5.6e-06 26.8 1.5 5.6e-06 26.8 1.5 1.6 2 0 0 2 2 2 1 ShK domain-like AhpC-TSA PF00578.21 GAX24657.1 - 0.00091 19.1 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Rad10 PF03834.14 GAX24658.1 - 6.6e-42 142.1 0.1 1.1e-41 141.4 0.1 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.7 GAX24658.1 - 0.00018 21.5 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GAX24658.1 - 0.081 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain NAD_binding_10 PF13460.6 GAX24659.1 - 7.1e-23 81.4 0.0 9.4e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX24659.1 - 0.026 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAX24660.1 - 4.9e-20 72.0 0.0 6.2e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX24660.1 - 2.8e-16 59.4 0.0 3.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX24660.1 - 5.6e-10 38.8 0.0 9.8e-08 31.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 GAX24660.1 - 7e-09 35.5 0.0 8.8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAX24660.1 - 9.2e-08 32.2 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX24660.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 GAX24660.1 - 0.014 15.3 0.0 0.052 13.5 0.0 1.9 2 1 0 2 2 2 0 KR domain TPR_12 PF13424.6 GAX24661.1 - 2.3e-05 24.6 10.8 0.0096 16.2 0.2 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat Cep57_CLD_2 PF14197.6 GAX24661.1 - 0.084 13.0 0.7 0.23 11.6 0.7 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TPR_2 PF07719.17 GAX24661.1 - 0.094 12.9 7.5 1 9.6 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX24661.1 - 0.28 12.1 0.1 0.28 12.1 0.1 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24661.1 - 0.34 10.8 2.4 5.3 7.0 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 GAX24661.1 - 0.52 9.7 5.6 1.5 8.2 0.1 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 GAX24661.1 - 2.5 8.8 13.6 1.2 9.9 1.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 GAX24662.1 - 1.2e-21 77.2 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 GAX24663.1 - 9.9e-23 80.7 0.0 1.8e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LCAT PF02450.15 GAX24664.1 - 1.3e-72 245.2 0.0 2.1e-72 244.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Pro_isomerase PF00160.21 GAX24665.1 - 6.7e-28 98.0 0.0 1.4e-27 96.9 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ACC_epsilon PF13822.6 GAX24666.1 - 0.018 15.7 1.5 0.031 15.0 1.5 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Methyltransf_23 PF13489.6 GAX24667.1 - 7.9e-08 32.3 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX24667.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAX24667.1 - 0.0072 16.1 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 GAX24667.1 - 0.014 16.1 0.0 0.023 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAX24667.1 - 0.018 14.8 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAX24667.1 - 0.08 13.6 0.0 0.16 12.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ADP_ribosyl_GH PF03747.14 GAX24670.1 - 1.6e-32 113.4 0.1 4.2e-32 112.0 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase Ank_5 PF13857.6 GAX24671.1 - 1.7e-12 47.3 0.0 6.8e-07 29.5 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX24671.1 - 5.1e-08 33.4 0.0 4.9e-05 23.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX24671.1 - 1e-06 29.2 0.0 0.0011 19.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX24671.1 - 1e-06 28.9 0.0 0.052 14.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAX24671.1 - 0.00027 21.1 0.1 3.1 8.7 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Spectrin PF00435.21 GAX24671.1 - 0.41 11.2 22.1 0.086 13.3 1.1 3.9 1 1 3 4 4 4 0 Spectrin repeat End3 PF12761.7 GAX24671.1 - 0.57 10.3 20.9 0.062 13.5 12.4 2.2 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 PKcGMP_CC PF16808.5 GAX24671.1 - 0.99 9.3 10.7 0.18 11.7 0.3 4.0 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_60s PF00428.19 GAX24672.1 - 3.6e-15 56.3 7.2 4.7e-15 56.0 7.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein GHMP_kinases_N PF00288.26 GAX24672.1 - 0.0037 17.5 3.6 0.0037 17.5 3.6 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GST_C PF00043.25 GAX24673.1 - 1.9e-13 50.5 0.1 2.7e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX24673.1 - 7.4e-07 29.1 0.0 1.6e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX24673.1 - 7.7e-05 22.8 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 GAX24673.1 - 0.0017 18.7 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAX24673.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAX24673.1 - 0.034 14.5 0.1 0.1 13.0 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 GAX24673.1 - 0.09 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 GAX24673.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HA PF03457.14 GAX24674.1 - 1.6e-16 60.4 2.9 8.1e-10 38.9 0.0 3.4 3 0 0 3 3 3 3 Helicase associated domain DUF4332 PF14229.6 GAX24676.1 - 0.0028 17.9 2.4 0.0097 16.1 0.2 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) CCDC-167 PF15188.6 GAX24677.1 - 0.076 13.4 1.9 0.13 12.6 1.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PetL PF05115.14 GAX24678.1 - 0.41 10.7 2.2 0.96 9.5 2.2 1.6 1 1 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Trypan_PARP PF05887.11 GAX24679.1 - 0.011 15.7 25.5 0.011 15.7 25.5 1.8 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF2868 PF11067.8 GAX24679.1 - 0.015 14.8 0.1 0.016 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TonB_N PF16031.5 GAX24679.1 - 6.3 7.3 27.4 26 5.3 27.5 1.9 1 1 0 1 1 1 0 TonB polyproline region NTF2 PF02136.20 GAX24680.1 - 5.3e-26 91.5 0.1 5.9e-26 91.4 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 GAX24680.1 - 0.013 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 SnoaL_2 PF12680.7 GAX24680.1 - 0.042 14.5 0.0 0.056 14.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Fibrillarin PF01269.17 GAX24681.1 - 1e-103 345.3 0.0 1.3e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 GAX24681.1 - 0.00026 20.8 0.0 0.00043 20.0 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 GAX24681.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) VKOR PF07884.14 GAX24682.1 - 7.3e-15 55.2 2.6 9.7e-15 54.9 2.6 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family COX16 PF14138.6 GAX24683.1 - 0.06 13.9 1.0 8.4 7.0 0.4 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF3306 PF11748.8 GAX24683.1 - 1.5 9.7 8.4 2.4 9.0 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Sec23_trunk PF04811.15 GAX24684.1 - 4.8e-08 32.9 0.0 8.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX24684.1 - 6.1e-05 22.8 0.0 0.0002 21.1 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAX24684.1 - 0.06 14.1 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain FbpA PF05833.11 GAX24684.1 - 0.095 11.4 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) TPR_7 PF13176.6 GAX24685.1 - 0.004 17.1 0.2 2.2 8.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX24685.1 - 0.0072 16.6 0.2 0.2 12.0 0.0 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat eIF3_N PF09440.10 GAX24686.1 - 5.8e-38 130.3 3.5 7.6e-38 130.0 0.2 2.7 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 GAX24686.1 - 1.9e-05 25.1 0.0 6.7e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 GAX24686.1 - 0.1 12.7 0.1 1.5 9.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp_protease_2 PF13650.6 GAX24687.1 - 1.5e-11 44.8 0.0 1.7e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GAX24687.1 - 1.2e-05 25.7 0.0 0.0027 18.2 0.0 3.2 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAT_signal PF10518.9 GAX24687.1 - 0.052 13.4 0.6 0.16 11.9 0.6 1.9 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence HSF_DNA-bind PF00447.17 GAX24688.1 - 2.2e-16 60.3 0.5 3.8e-16 59.5 0.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Bac_globin PF01152.21 GAX24689.1 - 1.8e-11 44.2 0.1 4e-11 43.1 0.1 1.5 1 1 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 GAX24689.1 - 9e-05 22.4 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Protoglobin Bac_globin PF01152.21 GAX24690.1 - 2.5e-19 69.6 0.1 6.6e-08 32.7 0.0 3.2 2 2 0 2 2 2 2 Bacterial-like globin Protoglobin PF11563.8 GAX24690.1 - 9.7e-05 22.3 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 2 Protoglobin DUF5030 PF16433.5 GAX24690.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5030) Mis14 PF08641.12 GAX24691.1 - 0.039 14.3 0.6 0.081 13.2 0.6 1.5 1 0 0 1 1 1 0 Kinetochore protein Mis14 like WEMBL PF05701.11 GAX24691.1 - 0.053 12.2 0.6 0.092 11.4 0.6 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light SlyX PF04102.12 GAX24691.1 - 0.33 11.6 2.9 0.58 10.8 1.1 2.4 2 0 0 2 2 2 0 SlyX Vps51 PF08700.11 GAX24691.1 - 0.38 10.9 2.0 0.74 9.9 0.3 2.2 2 0 0 2 2 2 0 Vps51/Vps67 RRM_1 PF00076.22 GAX24692.1 - 4.3e-19 68.1 0.0 2.4e-05 24.1 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAX24692.1 - 0.00039 20.2 0.0 2.1 8.2 0.0 3.3 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_9 PF18444.1 GAX24692.1 - 0.0064 16.3 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Vps16_N PF04841.13 GAX24693.1 - 2.3e-50 171.6 0.0 7e-49 166.7 0.0 2.1 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 GAX24693.1 - 3.2e-34 118.4 1.5 6.3e-34 117.5 1.5 1.5 1 1 0 1 1 1 1 Vps16, C-terminal region DUF4375 PF14300.6 GAX24693.1 - 0.098 12.9 0.9 52 4.1 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4375) HSF_DNA-bind PF00447.17 GAX24694.1 - 1.3e-15 57.7 0.1 3.6e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding HTH_IclR PF09339.10 GAX24694.1 - 0.099 12.5 1.2 5.8 6.8 0.2 2.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain OHCU_decarbox PF09349.10 GAX24695.1 - 1.4e-39 136.0 0.1 2e-39 135.6 0.1 1.2 1 0 0 1 1 1 1 OHCU decarboxylase Transthyretin PF00576.21 GAX24695.1 - 9.3e-29 100.3 0.0 1.7e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 HIUase/Transthyretin family DnaG_DnaB_bind PF08278.11 GAX24695.1 - 0.011 16.3 0.7 0.031 14.9 0.6 1.8 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding PH PF00169.29 GAX24696.1 - 1.2e-08 35.4 0.0 2.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 GAX24696.1 - 3.2e-05 24.0 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 PH domain CRAL_TRIO PF00650.20 GAX24696.1 - 0.0084 15.8 0.0 0.021 14.5 0.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain PH_6 PF15406.6 GAX24696.1 - 0.017 15.4 0.2 0.06 13.6 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain EMG1 PF03587.14 GAX24696.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 EMG1/NEP1 methyltransferase Pkinase PF00069.25 GAX24697.1 - 6.5e-24 84.7 0.0 9.2e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX24697.1 - 1.9e-18 66.7 0.0 2.5e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX24697.1 - 0.08 12.2 0.0 0.25 10.6 0.0 1.6 1 1 0 1 1 1 0 Kinase-like PHD PF00628.29 GAX24699.1 - 2.2e-08 33.9 19.3 1.9e-05 24.4 1.9 4.1 4 0 0 4 4 4 2 PHD-finger PWWP PF00855.17 GAX24699.1 - 9.5e-08 32.3 0.1 4.1e-07 30.3 0.1 2.2 1 0 0 1 1 1 1 PWWP domain Bromodomain PF00439.25 GAX24699.1 - 5.1e-06 26.5 0.1 1.1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Bromodomain ISP3_C PF18045.1 GAX24699.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ISP3 C-terminal PhnA_Zn_Ribbon PF08274.12 GAX24699.1 - 0.36 10.8 10.3 1 9.4 2.0 3.8 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-ANAPC11 PF12861.7 GAX24699.1 - 2.6 8.2 9.5 15 5.8 4.9 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PWWP PF00855.17 GAX24701.1 - 2.1e-10 40.8 0.1 1.1e-09 38.6 0.0 2.3 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 GAX24701.1 - 4.1e-09 36.2 20.5 4.6e-07 29.6 3.0 4.0 4 0 0 4 4 4 2 PHD-finger RAG2_PHD PF13341.6 GAX24701.1 - 0.02 14.9 0.2 0.05 13.7 0.2 1.6 1 0 0 1 1 1 0 RAG2 PHD domain ADK_lid PF05191.14 GAX24701.1 - 0.025 14.5 0.3 0.025 14.5 0.3 4.1 3 1 0 3 3 3 0 Adenylate kinase, active site lid zinc_ribbon_10 PF10058.9 GAX24701.1 - 0.52 10.1 23.5 0.76 9.5 1.0 5.7 4 1 2 6 6 6 0 Predicted integral membrane zinc-ribbon metal-binding protein Agenet PF05641.12 GAX24701.1 - 0.78 10.3 7.0 0.36 11.3 0.1 3.6 4 0 0 4 4 4 0 Agenet domain Prok-RING_1 PF14446.6 GAX24701.1 - 4.2 7.4 24.0 0.027 14.4 3.4 4.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 PWWP PF00855.17 GAX24702.1 - 6.6e-11 42.5 0.1 4.7e-10 39.8 0.0 2.4 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 GAX24702.1 - 8.4e-08 32.0 21.5 3.8e-06 26.7 5.3 3.6 4 0 0 4 4 4 2 PHD-finger Bromodomain PF00439.25 GAX24702.1 - 0.00029 20.8 0.1 0.00072 19.6 0.1 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 GAX24702.1 - 0.0029 17.1 3.4 0.0029 17.1 3.4 4.7 3 2 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 GAX24702.1 - 0.01 15.8 2.9 0.01 15.8 2.9 4.5 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 RAG2_PHD PF13341.6 GAX24702.1 - 0.02 14.9 0.1 0.053 13.6 0.1 1.6 1 0 0 1 1 1 0 RAG2 PHD domain Agenet PF05641.12 GAX24702.1 - 0.023 15.2 1.3 15 6.1 0.0 3.9 3 0 0 3 3 3 0 Agenet domain PHD PF00628.29 GAX24703.1 - 1.5e-25 88.9 79.3 2.1e-08 33.9 5.4 8.0 7 1 1 8 8 7 5 PHD-finger FYRN PF05964.14 GAX24703.1 - 1.1e-19 70.0 0.0 2.8e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 GAX24703.1 - 1.6e-18 67.7 0.5 5.6e-17 62.6 0.2 3.2 2 1 0 2 2 2 1 SET domain Bromodomain PF00439.25 GAX24703.1 - 2.4e-13 49.9 0.2 6.4e-13 48.6 0.2 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 GAX24703.1 - 3.4e-12 46.6 0.2 1.1e-11 45.0 0.2 1.9 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H PF13771.6 GAX24703.1 - 5e-11 42.7 8.5 5e-11 42.7 8.5 6.4 6 0 0 6 6 5 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAX24703.1 - 7e-10 39.1 3.8 7e-10 39.1 3.8 6.6 7 1 0 8 8 7 2 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 GAX24703.1 - 3e-05 23.9 13.6 8.8e-05 22.4 2.5 7.7 8 0 0 8 8 6 2 Prokaryotic RING finger family 1 FYRC PF05965.14 GAX24703.1 - 0.00034 20.7 0.0 0.00095 19.3 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus RAG2_PHD PF13341.6 GAX24703.1 - 0.088 12.9 0.1 0.088 12.9 0.1 4.0 5 0 0 5 5 4 0 RAG2 PHD domain N-SET PF11764.8 GAX24703.1 - 0.17 12.0 3.3 0.46 10.6 3.3 1.7 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N AT_hook PF02178.19 GAX24703.1 - 0.59 10.2 5.1 2 8.6 5.1 2.0 1 0 0 1 1 1 0 AT hook motif XRN_N PF03159.18 GAX24704.1 - 5.8e-85 284.6 0.0 7.9e-85 284.1 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 GAX24704.1 - 9.7e-80 268.7 0.1 3.4e-51 174.6 0.4 2.3 2 0 0 2 2 2 2 Xrn1 helical domain Arm-DNA-bind_4 PF14657.6 GAX24704.1 - 0.15 11.9 3.3 0.11 12.2 0.6 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain HSF_DNA-bind PF00447.17 GAX24705.1 - 9.5e-16 58.2 3.2 9.9e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding Chloroa_b-bind PF00504.21 GAX24706.1 - 1.5e-35 123.1 0.3 2e-35 122.7 0.3 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EamA PF00892.20 GAX24708.1 - 9.2e-18 64.7 14.2 4.4e-10 39.9 5.0 3.3 4 0 0 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAX24708.1 - 0.022 13.9 1.1 2.2 7.4 0.2 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter DctQ PF04290.12 GAX24708.1 - 7.2 6.5 10.8 0.94 9.4 1.8 3.2 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Methyltransf_11 PF08241.12 GAX24709.1 - 1.7e-12 47.8 0.0 8.2e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX24709.1 - 1.5e-10 41.7 0.0 1.1e-08 35.6 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX24709.1 - 2e-10 40.7 0.0 6.1e-09 35.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX24709.1 - 1e-05 26.2 0.2 2.9e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX24709.1 - 0.068 12.5 0.0 0.73 9.1 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Nop14 PF04147.12 GAX24709.1 - 0.079 11.2 19.5 0.11 10.7 19.5 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAX24709.1 - 0.14 11.5 23.3 0.21 11.0 23.3 1.2 1 0 0 1 1 1 0 SDA1 Methyltransf_32 PF13679.6 GAX24709.1 - 0.49 10.4 0.0 0.49 10.4 0.0 2.3 1 1 0 2 2 2 0 Methyltransferase domain Hid1 PF12722.7 GAX24709.1 - 2.2 6.3 8.6 2.9 5.9 8.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.11 GAX24709.1 - 7 5.0 13.8 9.4 4.6 13.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1479 PF07350.12 GAX24710.1 - 3.8e-08 32.5 0.2 1.4e-06 27.3 0.1 2.4 2 2 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 GAX24710.1 - 0.00045 20.5 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) zf-LITAF-like PF10601.9 GAX24711.1 - 0.59 10.4 3.8 0.17 12.2 0.9 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Amino_oxidase PF01593.24 GAX24713.1 - 8e-67 226.5 0.0 3e-44 152.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX24713.1 - 2.6e-14 53.2 0.2 6.6e-14 51.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX24713.1 - 2.2e-07 30.8 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX24713.1 - 2.3e-07 30.2 0.1 3.7e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAX24713.1 - 1.3e-06 28.1 0.6 1.5e-05 24.5 0.1 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX24713.1 - 1.1e-05 24.9 0.1 2e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX24713.1 - 8.3e-05 22.0 0.3 0.00059 19.2 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAX24713.1 - 9.5e-05 21.3 0.1 0.00017 20.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 GAX24713.1 - 0.00018 22.0 0.2 0.00049 20.6 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX24713.1 - 0.00057 19.2 0.1 0.00097 18.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAX24713.1 - 0.0095 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAX24713.1 - 0.012 15.6 0.1 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 GAX24713.1 - 0.079 12.0 0.2 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAX24713.1 - 0.14 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YjeF_N PF03853.15 GAX24713.1 - 0.18 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Sua5_yciO_yrdC PF01300.18 GAX24714.1 - 0.0097 15.4 0.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 2 Telomere recombination DAGAT PF03982.13 GAX24716.1 - 1.9e-28 99.3 0.0 2.3e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Comm PF15957.5 GAX24716.1 - 0.2 12.0 0.2 0.33 11.3 0.2 1.4 1 0 0 1 1 1 0 Commissureless Geminin PF07412.12 GAX24716.1 - 0.28 10.9 1.8 0.55 9.9 1.8 1.4 1 0 0 1 1 1 0 Geminin Ras PF00071.22 GAX24718.1 - 7.7e-28 97.1 0.0 1.7e-24 86.3 0.0 2.8 2 1 0 2 2 2 2 Ras family Roc PF08477.13 GAX24718.1 - 1.5e-20 73.6 0.0 1.6e-19 70.3 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX24718.1 - 2.8e-11 43.2 0.0 8.8e-10 38.3 0.0 2.8 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX24718.1 - 3.9e-07 30.1 0.0 1.4e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX24718.1 - 9.9e-07 28.3 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 GAX24718.1 - 0.00012 22.4 0.2 0.0024 18.1 0.0 2.7 2 2 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 GAX24718.1 - 0.0022 17.6 0.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 GAX24718.1 - 0.0075 16.7 0.2 0.016 15.6 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 GAX24718.1 - 0.018 14.6 0.1 0.69 9.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 GAX24718.1 - 0.029 13.6 0.1 0.61 9.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 GAX24718.1 - 0.043 13.9 0.1 4.5 7.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Nab1 PF04902.12 GAX24718.1 - 0.058 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Conserved region in Nab1 PAC4 PF16093.5 GAX24719.1 - 1.2e-12 47.8 0.0 2.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 PAP_assoc PF03828.19 GAX24721.1 - 1e-09 38.5 0.4 2.5e-07 30.8 0.0 3.6 3 0 0 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAX24721.1 - 1.7e-07 31.4 0.0 4.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF711 PF05167.12 GAX24722.1 - 7.9e-93 311.6 0.0 1e-92 311.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) PAP_central PF04928.17 GAX24723.1 - 6.7e-60 202.1 0.0 1.7e-59 200.8 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAX24723.1 - 3.1e-10 39.9 0.4 9.2e-08 31.9 0.0 2.9 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAX24723.1 - 0.00022 21.5 0.0 0.00062 20.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ku_C PF03730.14 GAX24723.1 - 2.7 8.8 7.5 8.4 7.2 7.5 1.8 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm AhpC-TSA_2 PF13911.6 GAX24724.1 - 3.7e-17 62.5 0.0 1.8e-16 60.3 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme MFS_5 PF05631.14 GAX24725.1 - 2.6e-38 131.9 7.4 1.2e-33 116.6 2.7 2.9 2 1 0 3 3 3 2 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAX24725.1 - 5.1e-09 35.5 21.8 5.9e-07 28.7 8.4 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily CCDC24 PF15669.5 GAX24725.1 - 0.28 11.0 4.5 0.51 10.2 4.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Adeno_E3 PF06040.11 GAX24725.1 - 0.86 9.8 8.0 2 8.6 0.1 3.4 4 0 0 4 4 4 0 Adenovirus E3 protein LRR_6 PF13516.6 GAX24726.1 - 1.2e-31 106.0 16.9 0.00014 21.6 0.0 10.5 10 0 0 10 10 10 9 Leucine Rich repeat LRR_4 PF12799.7 GAX24726.1 - 1.5e-10 41.2 6.9 0.032 14.7 0.2 7.0 3 2 6 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX24726.1 - 6.3e-07 29.1 12.1 0.04 13.7 1.1 6.7 6 3 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 GAX24726.1 - 8.9e-07 28.6 3.1 26 5.9 0.0 7.7 8 1 0 8 8 8 1 Leucine Rich Repeat HAD_2 PF13419.6 GAX24727.1 - 1e-08 35.4 0.0 1.3e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX24727.1 - 3.9e-07 30.6 0.0 5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX24727.1 - 4.5e-06 26.6 0.0 7.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like zf-RING_2 PF13639.6 GAX24728.1 - 2.4e-11 43.8 15.8 4.3e-11 42.9 15.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX24728.1 - 3.7e-07 29.8 13.1 8.3e-07 28.6 13.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAX24728.1 - 3.4e-06 27.2 12.9 8.8e-06 25.9 12.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX24728.1 - 2.4e-05 24.3 11.0 4.7e-05 23.3 11.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX24728.1 - 3.9e-05 23.5 15.0 6.9e-05 22.7 15.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAX24728.1 - 0.00019 21.3 15.2 0.00035 20.4 15.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX24728.1 - 0.00024 20.9 14.9 0.00041 20.1 14.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX24728.1 - 0.004 17.0 10.8 0.0066 16.3 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX24728.1 - 0.009 15.8 11.1 0.017 14.9 11.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX24728.1 - 0.037 14.1 8.7 0.11 12.5 8.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX24728.1 - 0.066 12.8 11.0 0.13 11.9 11.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ABA_GPCR PF12430.8 GAX24729.1 - 2.3e-15 56.8 6.2 2.3e-15 56.8 6.2 2.0 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 GAX24729.1 - 1.4e-10 41.1 0.0 6e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal LMBR1 PF04791.16 GAX24729.1 - 3.1e-05 23.1 0.1 3.1e-05 23.1 0.1 3.4 3 2 0 3 3 3 1 LMBR1-like membrane protein DUF2353 PF09789.9 GAX24729.1 - 0.05 13.0 0.1 0.082 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) ERGIC_N PF13850.6 GAX24729.1 - 0.16 12.3 1.6 15 6.0 0.0 3.6 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Vut_1 PF02592.15 GAX24729.1 - 8.2 6.7 18.3 0.37 11.1 0.1 4.0 4 0 0 4 4 4 0 Putative vitamin uptake transporter AAA PF00004.29 GAX24730.1 - 3.8e-39 134.1 0.0 7.2e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX24730.1 - 3.3e-07 30.0 0.0 7.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 GAX24730.1 - 9.1e-07 28.8 0.0 7.2e-06 25.9 0.0 2.6 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 GAX24730.1 - 4.5e-06 26.7 0.1 2.1e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX24730.1 - 5.1e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX24730.1 - 0.00054 20.4 0.8 0.0025 18.2 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 GAX24730.1 - 0.00092 18.5 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 GAX24730.1 - 0.0041 17.4 0.3 0.055 13.7 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAX24730.1 - 0.0051 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 GAX24730.1 - 0.016 14.8 0.7 1.2 8.7 0.1 3.0 1 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 GAX24730.1 - 0.039 14.5 0.0 0.083 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAX24730.1 - 0.055 13.5 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAX24730.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 GAX24730.1 - 0.082 13.3 0.0 0.25 11.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 GAX24730.1 - 0.097 11.7 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 GAX24730.1 - 0.11 11.9 0.1 0.28 10.5 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 GAX24730.1 - 0.19 11.4 0.0 4 7.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 GAX24730.1 - 0.33 10.3 1.8 2.4 7.4 0.1 2.9 3 1 1 4 4 4 0 KaiC DGCR6 PF07324.11 GAX24731.1 - 0.56 9.8 3.6 1.1 8.8 3.6 1.4 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein WBS_methylT PF12589.8 GAX24733.1 - 8.2e-14 52.1 9.8 8.2e-14 52.1 9.8 2.2 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 GAX24733.1 - 4.9e-12 46.3 0.0 8.1e-11 42.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX24733.1 - 1.4e-11 44.9 0.1 8.5e-09 36.0 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX24733.1 - 2.6e-09 37.7 0.0 5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX24733.1 - 4.9e-05 23.2 0.0 8.5e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX24733.1 - 0.00034 20.4 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GAX24733.1 - 0.0023 17.7 0.0 2.4 7.8 0.0 2.4 2 1 0 2 2 2 2 DNA methylase CMAS PF02353.20 GAX24733.1 - 0.013 14.8 0.0 1 8.6 0.1 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 GAX24733.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAX24733.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 GAX24733.1 - 0.019 14.3 0.0 0.089 12.1 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 GAX24733.1 - 0.03 14.6 0.0 0.096 13.0 0.0 1.8 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Pterin_4a PF01329.19 GAX24734.1 - 9.1e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase zinc_ribbon_6 PF14599.6 GAX24735.1 - 1.2e-23 82.9 0.7 1.2e-23 82.9 0.7 3.4 3 1 1 4 4 2 1 Zinc-ribbon zf-CHY PF05495.12 GAX24735.1 - 1.6e-12 47.7 11.6 1.6e-12 47.7 11.6 4.6 3 1 1 4 4 2 1 CHY zinc finger zf-RING_2 PF13639.6 GAX24735.1 - 3.3e-08 33.7 5.9 3.3e-08 33.7 5.9 4.7 4 1 1 5 5 3 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX24735.1 - 7.1e-05 22.7 5.9 7.1e-05 22.7 5.9 3.5 3 0 0 3 3 3 1 RING-type zinc-finger Hemerythrin PF01814.23 GAX24735.1 - 0.00035 21.2 12.0 0.0015 19.1 9.5 2.7 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Prok-RING_4 PF14447.6 GAX24735.1 - 0.0043 16.9 0.5 0.0043 16.9 0.5 4.4 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 HypA PF01155.19 GAX24735.1 - 0.024 14.6 0.7 0.024 14.6 0.7 4.9 1 1 2 3 3 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF521 PF04412.13 GAX24735.1 - 0.034 12.9 0.7 0.072 11.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF521) Glycos_trans_3N PF02885.17 GAX24735.1 - 0.09 12.6 0.3 5.4 7.0 0.2 2.8 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain RAC_head PF16717.5 GAX24735.1 - 0.2 12.7 2.5 0.36 11.8 0.2 2.6 2 1 1 3 3 3 0 Ribosome-associated complex head domain zf-RING_11 PF17123.5 GAX24735.1 - 0.2 11.4 7.7 0.23 11.2 4.4 2.9 2 0 0 2 2 2 0 RING-like zinc finger PDZ_6 PF17820.1 GAX24737.1 - 3.4e-08 33.2 0.0 0.12 12.2 0.0 4.6 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 GAX24737.1 - 6.5e-05 23.2 0.0 4.6 7.7 0.0 4.0 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 GAX24737.1 - 0.0022 18.3 0.4 0.94 9.8 0.0 4.5 5 0 0 5 5 5 1 PDZ domain Tristanin_u2 PF16638.5 GAX24737.1 - 6.5 7.6 10.2 5.5 7.8 2.8 3.3 2 1 0 3 3 3 0 Unstructured region on methyltransferase between zinc-fingers Myb_DNA-bind_6 PF13921.6 GAX24739.1 - 2.7e-17 62.7 14.8 5.1e-08 33.0 0.1 5.3 4 2 1 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAX24739.1 - 2.8e-05 24.2 10.9 0.13 12.5 0.1 5.4 6 0 0 6 6 6 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GAX24739.1 - 0.037 14.4 0.4 0.49 10.8 0.1 3.1 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 GAX24739.1 - 0.26 11.3 3.5 8.8 6.4 0.0 4.0 4 3 0 4 4 4 0 SLIDE TauD PF02668.16 GAX24740.1 - 2.9e-35 122.4 0.8 3.8e-35 122.0 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2700 PF10912.8 GAX24741.1 - 0.0062 16.6 0.8 0.01 15.9 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2700) PhaC_N PF07167.13 GAX24741.1 - 0.015 14.9 0.3 0.11 12.2 0.1 2.0 1 1 1 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Pentapeptide PF00805.22 GAX24742.1 - 1.9e-16 59.4 7.8 2e-08 33.7 0.9 3.6 2 1 1 4 4 4 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GAX24742.1 - 1.1e-15 57.5 3.7 5.6e-07 29.6 0.1 2.7 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 GAX24742.1 - 4.8e-11 42.6 8.5 1.8e-05 24.8 2.0 2.7 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) A_deaminase PF00962.22 GAX24745.1 - 1.2e-53 182.6 0.6 9.2e-48 163.2 0.2 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 GAX24745.1 - 0.0066 16.0 0.3 0.0099 15.4 0.3 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAX24745.1 - 0.055 12.8 0.5 0.14 11.4 0.3 1.7 1 1 0 1 1 1 0 Amidohydrolase family Nrf1_activ_bdg PF10492.9 GAX24746.1 - 0.21 12.3 1.4 0.84 10.3 1.1 2.2 1 1 1 2 2 2 0 Nrf1 activator activation site binding domain ABC_membrane PF00664.23 GAX24747.1 - 1.5e-52 178.9 11.1 3.7e-52 177.7 11.1 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAX24747.1 - 2.5e-33 115.5 0.0 4.4e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAX24747.1 - 2.4e-06 28.0 0.0 6.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 GAX24747.1 - 0.00021 20.2 0.2 0.00039 19.3 0.2 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 GAX24747.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 GAX24747.1 - 0.0024 17.4 1.9 0.063 12.7 1.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX24747.1 - 0.0032 17.8 0.1 0.019 15.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 GAX24747.1 - 0.039 14.4 0.1 0.25 11.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 GAX24747.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 GAX24747.1 - 0.063 13.0 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 GAX24747.1 - 0.09 13.0 0.3 1.1 9.6 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAX24747.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 GAX24747.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF1772 PF08592.11 GAX24747.1 - 0.17 12.2 3.5 0.31 11.4 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) ANAPC3 PF12895.7 GAX24748.1 - 0.025 14.8 0.0 3.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAX24748.1 - 0.049 13.7 0.4 3.4 8.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX24748.1 - 8.7 7.5 7.9 10 7.2 0.2 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC2 PF08672.11 GAX24749.1 - 1.6e-21 76.5 0.8 4.2e-21 75.2 0.1 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 GAX24749.1 - 3.2e-17 62.4 2.4 2e-16 59.8 0.1 2.5 2 1 0 2 2 2 2 Cullin family XPC-binding PF09280.11 GAX24749.1 - 1.6 8.5 13.5 7.8 6.3 2.9 4.0 3 0 0 3 3 3 0 XPC-binding domain Ank_2 PF12796.7 GAX24750.1 - 3.7e-07 30.6 0.0 9.9e-07 29.3 0.0 1.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX24750.1 - 1.3e-06 28.5 0.1 4.4e-05 23.7 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX24750.1 - 1.8e-06 27.8 0.0 0.004 17.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAX24750.1 - 0.00011 22.7 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Cwf_Cwc_15 PF04889.12 GAX24750.1 - 0.043 13.6 12.7 0.08 12.7 12.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 GAX24750.1 - 0.41 10.2 10.4 0.6 9.7 10.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GAX24750.1 - 0.66 8.0 19.9 0.92 7.5 19.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3295 PF11702.8 GAX24750.1 - 1.6 8.0 11.9 3.3 7.0 11.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PPP4R2 PF09184.11 GAX24750.1 - 3.9 7.0 11.6 7 6.1 11.6 1.4 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GAX24750.1 - 4.4 5.4 14.5 6.1 4.9 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.7 GAX24751.1 - 6.5e-07 29.9 0.0 2.5e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX24751.1 - 2.5e-06 27.7 0.0 5.7e-05 23.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX24751.1 - 1e-05 25.5 0.0 0.0095 16.4 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 GAX24751.1 - 0.00012 22.5 0.0 0.00032 21.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Tom22 PF04281.13 GAX24751.1 - 0.23 11.2 3.1 0.41 10.4 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 GCIP PF13324.6 GAX24751.1 - 0.54 9.8 4.3 0.8 9.3 4.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF179 PF02622.15 GAX24752.1 - 3e-32 111.8 0.0 1.8e-21 76.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized ACR, COG1678 OTCace PF00185.24 GAX24752.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain KH_1 PF00013.29 GAX24753.1 - 6.1e-61 202.2 45.2 4e-09 36.2 0.0 11.8 11 0 0 11 11 11 9 KH domain SLS PF14611.6 GAX24753.1 - 3.6e-17 62.9 34.9 0.051 13.4 0.1 10.3 2 2 6 10 10 10 7 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 GAX24753.1 - 3e-16 59.0 30.2 0.006 16.4 0.3 9.4 8 1 1 9 9 9 6 KH domain KH_4 PF13083.6 GAX24753.1 - 1.1e-11 44.4 20.1 0.13 12.2 0.1 8.6 9 1 0 9 9 9 5 KH domain KH_5 PF13184.6 GAX24753.1 - 0.0072 16.4 17.0 4.1 7.6 0.2 6.7 7 0 0 7 7 6 1 NusA-like KH domain DUF1664 PF07889.12 GAX24753.1 - 0.066 13.2 0.1 0.066 13.2 0.1 6.8 9 0 0 9 9 9 0 Protein of unknown function (DUF1664) UPF0231 PF06062.11 GAX24753.1 - 0.086 13.1 1.6 1 9.7 0.0 3.5 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0231) Prefoldin_2 PF01920.20 GAX24753.1 - 0.11 12.4 0.0 0.11 12.4 0.0 6.1 6 1 0 7 7 7 0 Prefoldin subunit Sec8_exocyst PF04048.14 GAX24753.1 - 0.18 11.7 4.2 1.5 8.7 0.2 3.5 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain NBP1 PF08537.10 GAX24753.1 - 1.2 8.5 8.2 0.59 9.5 5.3 2.0 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 DUF4404 PF14357.6 GAX24753.1 - 4.2 8.1 17.6 1.8 9.3 4.6 5.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4404) GIT_CC PF16559.5 GAX24753.1 - 6.2 6.8 6.4 2.2 8.2 0.1 3.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2096 PF09869.9 GAX24753.1 - 6.4 6.8 11.9 0.52 10.4 0.9 4.2 4 1 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2096) GLE1 PF07817.13 GAX24753.1 - 6.5 5.9 6.4 2.1 7.5 0.0 3.1 3 1 0 3 3 3 0 GLE1-like protein FG-GAP_2 PF14312.6 GAX24754.1 - 5.6e-07 29.7 44.6 0.0059 16.8 0.5 7.9 8 0 0 8 8 8 5 FG-GAP repeat Lactonase PF10282.9 GAX24754.1 - 5.9e-05 22.5 2.1 0.0036 16.6 0.1 1.9 1 1 2 3 3 3 2 Lactonase, 7-bladed beta-propeller BPL_C PF02237.17 GAX24754.1 - 0.29 11.1 1.9 1.7 8.6 0.1 2.8 3 0 0 3 3 3 0 Biotin protein ligase C terminal domain KH_1 PF00013.29 GAX24756.1 - 0.053 13.3 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 KH domain Ysc84 PF04366.12 GAX24756.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Las17-binding protein actin regulator DUF839 PF05787.13 GAX24757.1 - 5.5e-10 39.0 8.2 5.6e-06 25.8 3.6 3.1 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF839) DUF839 PF05787.13 GAX24758.1 - 5.4e-10 39.1 12.4 5.9e-06 25.7 7.6 3.1 1 1 1 3 3 3 3 Bacterial protein of unknown function (DUF839) Cu-binding_MopE PF11617.8 GAX24758.1 - 2.9e-09 36.9 18.7 2.9e-09 36.9 18.7 2.6 3 0 0 3 3 3 1 Putative metal-binding motif PT PF04886.12 GAX24758.1 - 0.061 12.9 39.2 0.063 12.8 17.0 2.9 1 1 1 2 2 2 0 PT repeat Amido_AtzD_TrzD PF09663.10 GAX24758.1 - 0.19 10.7 0.6 0.28 10.2 0.6 1.1 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) ECH_1 PF00378.20 GAX24759.1 - 1.6e-43 148.9 0.0 1.9e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX24759.1 - 3.5e-15 56.3 0.0 4.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Retrotrans_gag PF03732.17 GAX24759.1 - 0.12 12.7 1.3 0.9 9.9 0.0 2.5 2 1 0 2 2 2 0 Retrotransposon gag protein DUF3119 PF11317.8 GAX24760.1 - 5.7e-28 97.7 0.1 8.3e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) MgrB PF13998.6 GAX24760.1 - 0.02 14.8 0.3 0.041 13.8 0.3 1.4 1 0 0 1 1 1 0 MgrB protein Toxin_35 PF10530.9 GAX24761.1 - 0.0003 20.7 3.3 0.0003 20.7 3.3 9.1 2 2 7 9 9 9 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold VWD PF00094.25 GAX24761.1 - 0.0021 18.3 2.4 0.029 14.7 2.4 2.5 1 1 0 1 1 1 1 von Willebrand factor type D domain DnaJ_C PF01556.18 GAX24762.1 - 0.0018 18.4 0.0 8.5 6.5 0.0 3.2 2 1 0 2 2 2 2 DnaJ C terminal domain PP-binding PF00550.25 GAX24763.1 - 7.6e-17 61.4 0.9 9.5e-17 61.1 0.9 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAX24763.1 - 1.9e-07 31.2 1.6 2.8e-07 30.7 1.6 1.3 1 1 0 1 1 1 1 Acyl-carrier PRD PF00874.20 GAX24763.1 - 0.16 12.3 0.3 0.25 11.7 0.3 1.2 1 0 0 1 1 1 0 PRD domain IMUP PF15761.5 GAX24765.1 - 0.21 12.3 0.2 0.21 12.3 0.2 2.8 2 1 1 3 3 3 0 Immortalisation up-regulated protein HSF_DNA-bind PF00447.17 GAX24766.1 - 6.9e-16 58.6 0.2 6.9e-16 58.6 0.2 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Activator_LAG-3 PF11498.8 GAX24766.1 - 0.0055 15.7 19.5 0.0064 15.5 19.5 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 HTH_9 PF08221.11 GAX24767.1 - 8e-16 57.9 2.1 7.5e-11 42.0 0.2 3.9 3 1 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 GAX24767.1 - 9.5e-08 31.9 1.0 0.0004 20.2 0.1 3.9 4 0 0 4 4 4 2 TFIIE alpha subunit Lact-deh-memb PF09330.11 GAX24768.1 - 2.9e-51 174.6 0.0 9.3e-51 172.9 0.0 1.9 1 1 0 1 1 1 1 D-lactate dehydrogenase, membrane binding FAD_binding_4 PF01565.23 GAX24768.1 - 6.9e-10 38.8 0.0 1.9e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GAX24768.1 - 2e-05 24.3 0.1 0.019 14.6 0.4 3.3 2 1 0 2 2 2 2 FAD linked oxidases, C-terminal domain HSF_DNA-bind PF00447.17 GAX24769.1 - 5e-26 91.1 0.1 6.8e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding 3-PAP PF12578.8 GAX24769.1 - 0.039 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-associated protein Med9 PF07544.13 GAX24769.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DEAD PF00270.29 GAX24770.1 - 2.4e-15 56.7 0.0 7e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DSHCT PF08148.12 GAX24770.1 - 6.8e-13 48.6 0.1 4.2e-12 46.0 0.0 2.5 2 0 0 2 2 2 1 DSHCT (NUC185) domain ResIII PF04851.15 GAX24770.1 - 7.7e-07 29.3 0.0 3.6e-06 27.1 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX24770.1 - 1.5e-06 28.5 0.0 1.5e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAX24770.1 - 8.5e-06 26.1 0.0 0.00011 22.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain Get5_C PF18514.1 GAX24770.1 - 0.18 11.6 2.1 0.82 9.4 0.3 3.0 2 0 0 2 2 2 0 Get5 C-terminal domain ABC_membrane PF00664.23 GAX24771.1 - 4.2e-37 128.3 31.9 5.9e-26 91.7 8.6 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX24771.1 - 6.5e-33 114.1 0.5 6.8e-20 72.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAX24771.1 - 7.6e-08 32.1 1.1 0.47 9.8 0.0 3.6 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAX24771.1 - 6.6e-07 29.9 1.4 0.00082 19.8 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAX24771.1 - 8.1e-07 28.7 0.6 0.0063 16.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX24771.1 - 1.2e-06 29.2 0.8 0.0079 16.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 GAX24771.1 - 3.1e-06 27.3 0.3 0.029 14.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 GAX24771.1 - 5.7e-06 26.4 6.9 0.018 14.9 0.0 4.2 4 1 1 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAX24771.1 - 1.3e-05 25.2 0.1 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GAX24771.1 - 1.9e-05 24.9 0.1 0.025 14.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAX24771.1 - 5.1e-05 22.5 0.0 0.0051 15.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 GAX24771.1 - 5.4e-05 23.4 0.5 0.05 13.7 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 GAX24771.1 - 0.00014 21.5 0.1 0.065 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 GAX24771.1 - 0.00048 20.2 2.9 0.013 15.6 0.2 3.5 3 0 0 3 3 3 1 Dynamin family AAA_30 PF13604.6 GAX24771.1 - 0.00057 19.7 0.1 0.3 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX24771.1 - 0.00059 19.8 0.4 0.52 10.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 GAX24771.1 - 0.00075 19.1 0.4 0.19 11.3 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 GAX24771.1 - 0.0024 18.0 0.0 0.036 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAX24771.1 - 0.0032 16.7 0.2 1.8 7.7 0.1 2.5 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 GAX24771.1 - 0.0035 16.7 0.3 0.27 10.6 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 GAX24771.1 - 0.0036 16.6 0.1 0.052 12.8 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 GAX24771.1 - 0.0061 16.6 0.6 1.1 9.3 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 GAX24771.1 - 0.01 15.8 0.2 0.57 10.0 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 GAX24771.1 - 0.011 15.4 0.0 0.6 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 GAX24771.1 - 0.012 15.1 0.3 2.6 7.4 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.15 GAX24771.1 - 0.025 14.5 1.1 0.92 9.4 0.0 2.9 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.9 GAX24771.1 - 0.025 14.3 0.5 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 GAX24771.1 - 0.03 14.0 0.7 0.6 9.8 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.17 GAX24771.1 - 0.033 14.0 0.1 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 GAX24771.1 - 0.035 14.0 0.3 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 GAX24771.1 - 0.062 12.8 0.1 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.29 GAX24771.1 - 0.067 13.6 0.0 9.5 6.7 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 GAX24771.1 - 0.068 13.4 1.5 19 5.5 0.1 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 GAX24771.1 - 0.12 11.2 0.3 1.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Guanylate_kin PF00625.21 GAX24771.1 - 0.15 11.7 0.3 0.39 10.4 0.0 1.9 2 0 0 2 2 1 0 Guanylate kinase AAA_24 PF13479.6 GAX24771.1 - 0.17 11.5 0.7 8.9 6.0 0.1 2.7 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 GAX24771.1 - 0.18 11.0 0.1 7.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_18 PF13238.6 GAX24771.1 - 0.24 12.0 0.8 2.6 8.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain Abhydrolase_1 PF00561.20 GAX24772.1 - 3.1e-14 53.2 0.0 1.8e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX24772.1 - 1.2e-13 52.2 0.8 1.2e-13 52.2 0.8 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX24772.1 - 2.4e-10 40.1 0.0 3.1e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAX24772.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 GAX24772.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 GAX24772.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase NGP1NT PF08153.12 GAX24773.1 - 4.3e-39 133.6 0.6 8.7e-39 132.7 0.6 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 GAX24773.1 - 1.7e-17 63.6 0.0 2.8e-13 49.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX24773.1 - 9.3e-07 28.5 0.0 0.00017 21.2 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX24773.1 - 2.5e-05 24.2 0.0 7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GAX24773.1 - 0.0017 18.4 1.0 0.39 10.8 0.2 3.6 2 1 1 3 3 3 1 Dynamin family cobW PF02492.19 GAX24773.1 - 0.0083 15.7 0.0 1 8.9 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 GAX24773.1 - 0.025 14.0 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX24773.1 - 0.025 14.1 0.0 3.4 7.2 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Roc PF08477.13 GAX24773.1 - 0.032 14.5 0.0 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase His_Phos_1 PF00300.22 GAX24774.1 - 3.2e-15 56.3 0.0 4.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) IBN_N PF03810.19 GAX24775.1 - 2.6e-10 40.1 0.3 2.1e-09 37.1 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain GPAT_N PF14829.6 GAX24775.1 - 0.0026 17.7 0.2 4.5 7.3 0.0 3.6 3 0 0 3 3 3 2 Glycerol-3-phosphate acyltransferase N-terminal UCH PF00443.29 GAX24776.1 - 6.7e-41 140.5 0.0 9.5e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 GAX24776.1 - 2.9e-13 49.4 0.2 7.4e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 GAX24776.1 - 9.3e-09 35.3 0.1 2.3e-05 24.1 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAX24776.1 - 1.9e-07 31.3 0.0 7.5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 GAX24776.1 - 0.00097 18.8 0.0 0.0028 17.4 0.0 1.8 1 0 0 1 1 1 1 Variant UBP zinc finger Glyco_hydro_81 PF03639.13 GAX24777.1 - 3.8e-15 55.9 0.2 1.1e-14 54.3 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Glyco_hydro81C PF17652.1 GAX24777.1 - 1e-11 44.7 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro81C PF17652.1 GAX24778.1 - 1.1e-13 51.2 0.1 1.3e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain RGM_C PF06534.13 GAX24781.1 - 0.0044 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus VWD PF00094.25 GAX24781.1 - 0.095 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type D domain EF-hand_1 PF00036.32 GAX24781.1 - 2.6 7.8 7.6 14 5.5 2.0 2.6 2 0 0 2 2 2 0 EF hand PPR_1 PF12854.7 GAX24782.1 - 2.6e-49 164.6 0.4 0.0002 21.0 0.0 13.6 12 3 0 12 12 12 10 PPR repeat PPR_2 PF13041.6 GAX24782.1 - 5.8e-45 151.3 9.5 1.5e-06 28.2 0.1 10.5 6 4 4 10 10 10 10 PPR repeat family PPR_3 PF13812.6 GAX24782.1 - 2.5e-29 101.2 0.0 3.4e-05 23.8 0.0 10.9 8 4 3 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.20 GAX24782.1 - 2e-18 65.2 23.4 0.53 10.6 0.0 14.3 12 4 1 13 13 13 5 PPR repeat PPR_long PF17177.4 GAX24782.1 - 1.2e-15 57.5 2.8 0.0047 16.3 0.1 5.3 1 1 3 5 5 5 5 Pentacotripeptide-repeat region of PRORP DUF4614 PF15391.6 GAX24782.1 - 0.11 12.5 0.8 2.1 8.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Glu-tRNAGln PF02686.15 GAX24782.1 - 0.13 12.6 0.0 5.6 7.3 0.0 3.3 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit TC1 PF15063.6 GAX24782.1 - 0.42 10.5 4.9 10 6.1 0.0 4.8 5 1 1 6 6 6 0 Thyroid cancer protein 1 WD40 PF00400.32 GAX24783.1 - 4.9e-42 141.1 8.3 1.4e-08 35.2 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX24783.1 - 8.1e-17 61.3 0.1 0.00067 19.9 0.0 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX24783.1 - 6.6e-09 35.0 3.9 0.0029 16.3 0.0 4.8 2 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX24783.1 - 5.2e-08 32.2 4.1 0.00026 20.1 0.2 3.7 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 GAX24783.1 - 2.7e-05 22.7 0.0 0.041 12.2 0.0 2.9 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 GAX24783.1 - 9.1e-05 22.4 0.0 0.0015 18.5 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 GAX24783.1 - 0.0015 17.6 0.2 0.073 12.1 0.0 2.8 1 1 3 4 4 4 1 VID27 C-terminal WD40-like domain WD40_like PF17005.5 GAX24783.1 - 0.013 14.8 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 GAX24783.1 - 0.018 14.0 0.5 2.6 6.9 0.0 3.0 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 GAX24783.1 - 0.05 12.9 1.7 13 5.0 0.1 3.3 2 1 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 GAX24783.1 - 0.084 12.4 3.9 1.3 8.6 3.8 2.6 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.6 GAX24783.1 - 4.9 7.8 8.0 1.2 9.7 0.4 3.5 4 0 0 4 4 4 0 PQQ-like domain E1-E2_ATPase PF00122.20 GAX24784.1 - 3.5e-44 150.5 0.2 3.5e-44 150.5 0.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAX24784.1 - 4.1e-26 92.6 0.1 1.8e-25 90.5 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAX24784.1 - 1.4e-05 25.4 9.9 0.022 15.2 0.2 3.9 4 0 0 4 4 4 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAX24784.1 - 0.00071 19.4 2.1 0.022 14.5 0.4 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ninjurin PF04923.12 GAX24784.1 - 0.17 11.8 0.3 0.45 10.5 0.3 1.7 1 0 0 1 1 1 0 Ninjurin MitMem_reg PF13012.6 GAX24788.1 - 5.3e-08 33.3 0.4 1.2e-07 32.1 0.4 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAX24788.1 - 0.00019 21.4 0.1 0.01 15.8 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Coatomer_WDAD PF04053.14 GAX24789.1 - 4.8e-136 454.4 0.0 1.7e-135 452.5 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAX24789.1 - 1.7e-39 133.1 6.5 3.3e-08 34.0 0.1 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX24789.1 - 1.7e-07 31.4 0.1 1.5 9.1 0.0 5.8 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX24789.1 - 0.00019 21.4 0.0 0.53 10.1 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAX24789.1 - 0.042 12.5 0.1 9.1 4.8 0.0 3.7 3 2 1 4 4 4 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAX24789.1 - 0.12 11.0 0.5 4.8 5.8 0.1 3.2 2 2 2 4 4 4 0 Nup133 N terminal like TLD PF07534.16 GAX24791.1 - 0.00038 20.7 0.0 0.00053 20.2 0.0 1.2 1 0 0 1 1 1 1 TLD DUF4519 PF15012.6 GAX24792.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Glyco_transf_90 PF05686.12 GAX24793.1 - 7.3e-21 74.5 0.2 1.8e-20 73.2 0.2 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAX24793.1 - 0.00025 21.4 0.0 0.00057 20.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.12 GAX24794.1 - 3.4e-18 65.7 1.0 5.5e-18 65.0 1.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAX24794.1 - 0.0096 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mad3_BUB1_I PF08311.12 GAX24794.1 - 0.054 13.5 2.0 1.3 9.0 0.5 2.4 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 LON_substr_bdg PF02190.16 GAX24795.1 - 1.3e-05 25.2 0.1 2.1e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain TUDOR PF00567.24 GAX24795.1 - 0.077 13.0 0.1 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Tudor domain Baculo_gp64 PF03273.13 GAX24796.1 - 0.12 11.1 1.3 0.16 10.8 1.3 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family kleA_kleC PF17383.2 GAX24796.1 - 0.63 10.4 7.1 1.4 9.3 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A DUF3492 PF11997.8 GAX24796.1 - 1.1 8.9 6.6 0.14 11.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Chloroa_b-bind PF00504.21 GAX24797.1 - 6.9e-36 124.2 0.2 1.3e-35 123.3 0.2 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SQS_PSY PF00494.19 GAX24797.1 - 2e-35 122.6 3.1 2.6e-35 122.2 3.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Glyco_transf_34 PF05637.12 GAX24798.1 - 3.8e-25 89.0 0.4 1.2e-13 51.4 0.1 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GAX24798.1 - 2e-09 37.3 0.0 3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 GAX24798.1 - 0.41 10.6 2.4 0.79 9.7 0.9 2.3 2 1 0 2 2 2 0 Nucleotide-diphospho-sugar transferase Zn_clus PF00172.18 GAX24799.1 - 4.6e-09 36.3 7.7 1.1e-08 35.0 7.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD2_C PF04194.13 GAX24800.1 - 6.4e-34 117.5 4.2 1.7e-33 116.2 2.2 2.4 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain CpXC PF14353.6 GAX24800.1 - 0.044 13.8 1.5 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 CpXC protein Cwf_Cwc_15 PF04889.12 GAX24800.1 - 0.55 9.9 8.2 0.12 12.1 4.6 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ion_trans PF00520.31 GAX24801.1 - 1.7e-36 125.7 25.1 2.3e-36 125.3 25.1 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GAX24801.1 - 6.6e-08 31.7 17.4 0.00022 20.0 10.9 2.1 1 1 1 2 2 2 2 Polycystin cation channel EzrA PF06160.12 GAX24801.1 - 0.13 10.4 4.3 0.13 10.4 3.0 1.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ALIX_LYPXL_bnd PF13949.6 GAX24801.1 - 0.48 9.7 6.9 0.053 12.8 2.3 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV HR1 PF02185.16 GAX24801.1 - 4.6 7.4 9.4 1.2 9.3 2.7 2.4 2 0 0 2 2 2 0 Hr1 repeat DUF4011 PF13195.6 GAX24802.1 - 0.045 13.7 0.1 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) 60KD_IMP PF02096.20 GAX24802.1 - 0.054 13.4 0.3 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein adh_short_C2 PF13561.6 GAX24804.1 - 4.3e-49 167.2 0.4 5.3e-49 166.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX24804.1 - 4.3e-44 150.3 0.1 5.2e-44 150.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX24804.1 - 1.2e-06 28.6 0.1 1.8e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX24804.1 - 0.0022 17.5 0.5 1.3 8.5 0.2 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAX24804.1 - 0.53 9.6 3.8 0.86 8.9 0.1 2.8 3 1 1 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF872 PF05915.12 GAX24805.1 - 0.072 13.3 0.0 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Rsbr_N PF08678.10 GAX24805.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Rsbr N terminal GTP_EFTU PF00009.27 GAX24806.1 - 3.1e-49 167.1 0.0 4.7e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAX24806.1 - 1.1e-39 135.2 0.1 3.6e-39 133.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAX24806.1 - 1.4e-11 44.6 0.1 5.1e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX24806.1 - 3.8e-05 23.7 0.0 0.00026 21.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAX24806.1 - 0.0092 15.9 0.2 0.032 14.1 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 SRPRB PF09439.10 GAX24806.1 - 0.039 13.4 0.2 0.35 10.3 0.2 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CCT PF06203.14 GAX24807.1 - 1.2e-17 63.6 10.7 2.4e-17 62.7 10.7 1.5 1 0 0 1 1 1 1 CCT motif DUF2373 PF10180.9 GAX24808.1 - 1.9e-22 78.9 2.5 4e-22 77.8 2.5 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Silic_transp PF03842.13 GAX24808.1 - 0.056 11.7 0.1 0.056 11.7 0.1 1.6 2 0 0 2 2 2 0 Silicon transporter DUF4633 PF15464.6 GAX24808.1 - 0.95 9.6 3.8 0.34 11.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) Mt_ATP-synt_B PF05405.14 GAX24809.1 - 1.4e-16 60.5 2.9 1.4e-16 60.5 2.9 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CLP_protease PF00574.23 GAX24810.1 - 8.5e-48 162.6 0.0 1.8e-47 161.6 0.0 1.5 1 1 0 1 1 1 1 Clp protease AAA PF00004.29 GAX24811.1 - 8.2e-41 139.5 0.1 3.9e-40 137.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX24811.1 - 5.7e-11 42.1 0.4 1.1e-10 41.2 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GAX24811.1 - 1.9e-08 34.1 0.0 4.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 GAX24811.1 - 1e-05 25.8 0.3 0.004 17.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX24811.1 - 2.3e-05 24.4 0.1 0.00014 21.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX24811.1 - 4.2e-05 23.7 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAX24811.1 - 4.2e-05 22.8 0.0 7.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 GAX24811.1 - 6.5e-05 23.4 0.2 0.0015 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAX24811.1 - 0.00096 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 GAX24811.1 - 0.0022 17.4 0.1 0.3 10.4 0.1 2.3 1 1 1 2 2 2 1 KaiC IstB_IS21 PF01695.17 GAX24811.1 - 0.014 15.2 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 GAX24811.1 - 0.022 15.1 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 GAX24811.1 - 0.024 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 GAX24811.1 - 0.025 14.4 0.0 0.085 12.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAX24811.1 - 0.037 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAX24811.1 - 0.04 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 GAX24811.1 - 0.046 13.4 0.1 0.16 11.6 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 GAX24811.1 - 0.049 13.9 0.3 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAX24811.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAX24811.1 - 0.097 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GAX24811.1 - 0.098 12.6 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 GAX24811.1 - 0.12 11.8 0.2 0.29 10.5 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 GAX24811.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Vps35 PF03635.17 GAX24812.1 - 3.6e-214 713.4 0.0 4.3e-214 713.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TetR_C_18 PF17923.1 GAX24812.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_32N PF00251.20 GAX24813.1 - 2.6e-05 23.9 0.2 0.00065 19.4 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Usher_TcfC PF17271.2 GAX24813.1 - 0.0079 15.0 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 1 TcfC Usher-like barrel domain Ribosomal_L14e PF01929.17 GAX24814.1 - 6.7e-31 106.6 6.2 9.8e-31 106.1 6.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 GAX24814.1 - 0.024 14.6 0.1 0.084 12.9 0.1 1.9 1 1 0 1 1 1 0 KOW motif PRA-CH PF01502.18 GAX24815.1 - 5.5e-25 87.0 0.1 1.3e-24 85.8 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 GAX24815.1 - 1.5e-13 50.9 5.5 1.9e-13 50.7 3.7 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 GAX24815.1 - 9.2e-05 22.5 3.2 0.00014 21.9 0.6 2.3 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 GAX24815.1 - 0.015 15.5 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 MazG-like family Synapsin_C PF02750.14 GAX24818.1 - 0.094 12.2 0.0 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 Synapsin, ATP binding domain AD PF09793.9 GAX24820.1 - 1.4e-19 70.0 0.1 2.2e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 GAX24820.1 - 1.7e-06 27.6 0.7 0.00011 21.7 0.7 2.3 1 1 0 1 1 1 1 Gemin6 protein His_Phos_1 PF00300.22 GAX24821.1 - 4e-34 118.0 0.0 3.5e-30 105.1 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) GLE1 PF07817.13 GAX24822.1 - 3.6e-26 91.9 0.0 6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein zf-CCCH_4 PF18044.1 GAX24822.1 - 1.6e-11 43.7 4.8 3e-11 42.8 4.8 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAX24822.1 - 9.2e-08 31.9 8.2 1.6e-07 31.1 8.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAX24822.1 - 6.5e-07 29.1 4.7 1.2e-06 28.3 4.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAX24822.1 - 0.00026 21.7 0.8 0.00026 21.7 0.8 2.6 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 GAX24822.1 - 0.0018 18.6 5.2 0.0034 17.8 5.2 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Ribosomal_L7Ae PF01248.26 GAX24823.1 - 2e-12 46.7 0.1 4.6e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.22 GAX24823.1 - 1.9e-07 30.8 0.0 0.065 13.1 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAX24823.1 - 0.065 13.3 0.0 4.5 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA binding motif Glutaredoxin PF00462.24 GAX24825.1 - 2.6e-18 66.0 0.0 3.7e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin EF-hand_13 PF17958.1 GAX24825.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain GST_N_3 PF13417.6 GAX24825.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Arf PF00025.21 GAX24826.1 - 3.8e-74 247.9 0.0 4.3e-74 247.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAX24826.1 - 1.7e-14 54.0 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAX24826.1 - 3.6e-12 46.1 0.1 3.6e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAX24826.1 - 1.4e-11 44.2 0.0 1.6e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAX24826.1 - 2.8e-10 39.9 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX24826.1 - 9e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX24826.1 - 8.2e-07 28.6 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAX24826.1 - 0.00045 19.8 0.2 0.0028 17.2 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 GAX24826.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 GAX24826.1 - 0.15 12.6 0.0 0.21 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain Morc6_S5 PF17942.1 GAX24826.1 - 0.17 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like LTD PF00932.19 GAX24827.1 - 1.8e-16 60.5 0.6 2.7e-16 59.9 0.6 1.3 1 0 0 1 1 1 1 Lamin Tail Domain Aminotran_3 PF00202.21 GAX24828.1 - 6.7e-74 249.0 0.0 9.1e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAX24828.1 - 0.00036 19.9 0.0 0.00067 19.0 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Kelch_1 PF01344.25 GAX24829.1 - 5.1e-26 90.0 4.2 9.3e-09 34.7 0.1 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAX24829.1 - 1e-25 89.4 3.4 3e-09 36.7 0.0 5.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX24829.1 - 3.6e-24 84.2 1.9 1e-06 28.8 0.0 6.6 6 1 1 7 7 7 5 Kelch motif Kelch_3 PF13415.6 GAX24829.1 - 3e-22 78.4 3.8 1.6e-05 25.0 0.0 6.8 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAX24829.1 - 1.9e-17 62.9 2.4 8.2e-05 22.5 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 GAX24829.1 - 3.7e-14 52.0 6.7 0.0023 17.9 0.0 6.0 6 1 0 6 6 6 4 Kelch motif Pex19 PF04614.12 GAX24830.1 - 5.5e-34 118.0 17.5 5.5e-34 118.0 17.5 2.0 2 0 0 2 2 2 1 Pex19 protein family GET2 PF08690.10 GAX24830.1 - 0.0059 16.3 21.2 0.0059 16.3 21.2 2.2 1 1 1 2 2 2 1 GET complex subunit GET2 Corazonin PF17308.2 GAX24830.1 - 1.6 9.1 6.4 0.78 10.1 1.9 2.4 2 1 0 2 2 2 0 Pro-corazonin SnoaL PF07366.12 GAX24832.1 - 0.0064 16.3 0.0 0.068 13.0 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase Fer2_BFD PF04324.15 GAX24832.1 - 0.24 11.8 0.0 0.57 10.6 0.0 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain F_actin_cap_B PF01115.17 GAX24833.1 - 7.4e-39 133.8 0.0 8.7e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF4503 PF14951.6 GAX24833.1 - 0.025 13.0 0.1 0.034 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) EF-hand_1 PF00036.32 GAX24834.1 - 3.5e-10 38.7 0.1 0.00013 21.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAX24834.1 - 1.5e-09 38.1 0.8 3e-09 37.2 0.8 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX24834.1 - 8.4e-08 31.6 0.6 0.015 15.1 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX24834.1 - 0.00017 21.0 0.6 0.093 12.3 0.3 2.5 2 0 0 2 2 2 2 EF hand Neurensin PF14927.6 GAX24834.1 - 0.021 14.5 0.5 0.021 14.5 0.5 1.8 2 0 0 2 2 2 0 Neurensin SPARC_Ca_bdg PF10591.9 GAX24834.1 - 0.057 13.8 1.3 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3285 PF11688.8 GAX24834.1 - 0.066 13.1 2.0 0.17 11.8 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Phage_holin_3_6 PF07332.11 GAX24834.1 - 0.11 12.6 9.6 0.59 10.2 0.7 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PRA1 PF03208.19 GAX24834.1 - 1.3 8.7 5.6 2.1 8.0 5.6 1.2 1 0 0 1 1 1 0 PRA1 family protein Chordopox_A13L PF05961.11 GAX24834.1 - 1.3 9.3 3.8 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein GSHPx PF00255.19 GAX24835.1 - 4.1e-05 23.1 0.1 7.6e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 Glutathione peroxidase PRKCSH-like PF12999.7 GAX24836.1 - 2.3e-11 43.8 7.5 3.3e-11 43.3 7.5 1.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like DUF3797 PF12677.7 GAX24836.1 - 0.043 13.7 0.5 0.087 12.7 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3797) Ldl_recept_a PF00057.18 GAX24836.1 - 0.12 12.7 15.6 1.1 9.6 2.9 3.1 2 2 0 2 2 2 0 Low-density lipoprotein receptor domain class A Histidinol_dh PF00815.20 GAX24837.1 - 4.4e-129 431.1 0.4 5.4e-129 430.8 0.4 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase SIP PF04954.13 GAX24837.1 - 0.016 15.7 1.8 0.15 12.6 0.5 2.6 2 0 0 2 2 2 0 Siderophore-interacting protein DUF4936 PF16290.5 GAX24838.1 - 0.053 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) Mpv17_PMP22 PF04117.12 GAX24839.1 - 8.2e-18 64.4 1.4 1.5e-17 63.5 1.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Cyclin PF08613.11 GAX24840.1 - 0.036 14.4 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin MFS_1 PF07690.16 GAX24841.1 - 4.2e-10 39.1 41.2 4.2e-10 39.1 41.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily La PF05383.17 GAX24842.1 - 1.1e-13 51.0 0.0 2.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 La domain 60KD_IMP PF02096.20 GAX24843.1 - 5e-15 55.8 0.0 5e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein Acyl-CoA_dh_1 PF00441.24 GAX24844.1 - 2e-35 122.2 1.3 3.2e-35 121.5 1.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAX24844.1 - 3e-15 56.2 0.0 4.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAX24844.1 - 3.2e-13 50.1 0.8 5.9e-13 49.2 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX24844.1 - 5e-13 49.7 0.0 1.1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain RF-1 PF00472.20 GAX24845.1 - 5.1e-24 84.5 1.5 5.1e-24 84.5 1.5 1.7 2 0 0 2 2 2 1 RF-1 domain MJ1316 PF04457.12 GAX24845.1 - 3.9e-17 62.8 0.1 8.2e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Ribosomal_S17e PF00833.18 GAX24845.1 - 0.069 13.1 0.1 2.4 8.1 0.0 2.8 3 0 0 3 3 3 0 Ribosomal S17 FG-GAP_2 PF14312.6 GAX24846.1 - 3.2e-50 168.2 22.4 9.1e-10 38.6 0.2 7.3 7 0 0 7 7 7 7 FG-GAP repeat Aminotran_1_2 PF00155.21 GAX24847.1 - 5.9e-33 114.5 0.0 2e-32 112.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 GAX24847.1 - 0.0024 16.8 0.0 0.005 15.8 0.0 1.6 1 0 0 1 1 1 1 Allinase Chloroa_b-bind PF00504.21 GAX24851.1 - 1.7e-34 119.7 0.2 2.2e-34 119.4 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein BTB PF00651.31 GAX24854.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Radical_SAM PF04055.21 GAX24855.1 - 1.1e-29 104.0 0.0 1.8e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Mob_synth_C PF06463.13 GAX24855.1 - 1.3e-29 102.7 0.0 2.5e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Fer4_12 PF13353.6 GAX24855.1 - 1.5e-09 38.2 0.0 2.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GAX24855.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Oxidored_molyb PF00174.19 GAX24857.1 - 1.2e-52 177.9 0.0 2.1e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAX24857.1 - 1.7e-41 141.5 1.5 1.7e-41 141.5 1.5 1.6 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 GAX24857.1 - 2e-31 108.2 0.0 7.4e-31 106.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAX24857.1 - 3.3e-25 88.9 0.0 8.5e-25 87.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 GAX24857.1 - 6.1e-22 77.6 0.0 1.2e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 GAX24857.1 - 2.6e-06 27.7 0.0 3.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 GAX24858.1 - 1e-16 61.5 0.0 2.1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAX24858.1 - 0.2 11.8 0.0 2.7 8.1 0.0 2.4 3 0 0 3 3 3 0 Ferric reductase NAD binding domain Ank_5 PF13857.6 GAX24859.1 - 1.5e-06 28.4 0.0 0.0023 18.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX24859.1 - 2e-06 27.7 0.0 0.91 10.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 GAX24859.1 - 1.1e-05 26.0 0.0 0.00061 20.3 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX24859.1 - 0.00031 21.1 0.1 0.19 12.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat LMBR1 PF04791.16 GAX24859.1 - 0.43 9.4 8.4 0.55 9.1 8.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Lipoprotein_6 PF01441.19 GAX24859.1 - 0.48 10.4 9.2 0.041 13.9 2.9 2.1 1 1 1 2 2 2 0 Lipoprotein DUF724 PF05266.14 GAX24859.1 - 1.1 9.1 20.1 0.71 9.7 12.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 GAX24859.1 - 2 7.6 21.6 0.09 12.0 10.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein Tho2 PF11262.8 GAX24859.1 - 6.3 5.9 15.8 0.25 10.5 8.4 2.2 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Ank_2 PF12796.7 GAX24860.1 - 1.3e-30 105.9 0.1 1.9e-09 37.9 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX24860.1 - 8.4e-26 87.2 4.5 0.051 14.1 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 GAX24860.1 - 9.5e-25 86.7 3.0 6.8e-05 23.3 0.1 7.0 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX24860.1 - 6e-24 83.8 0.1 4.6e-05 23.6 0.0 6.5 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAX24860.1 - 5.7e-15 55.0 6.4 0.0014 19.0 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat DUF5492 PF17596.2 GAX24860.1 - 0.0002 21.6 0.3 35 4.8 0.0 5.3 5 0 0 5 5 5 0 Family of unknown function (DUF5492) HlyD_2 PF12700.7 GAX24860.1 - 0.18 10.5 0.8 0.27 9.9 0.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein TSP_1 PF00090.19 GAX24861.1 - 2.3e-11 43.7 112.7 1.7e-05 24.9 9.4 8.5 8 0 0 8 8 8 8 Thrombospondin type 1 domain DAZAP2 PF11029.8 GAX24862.1 - 0.0033 18.4 0.5 0.007 17.3 0.5 1.6 1 1 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) Borrelia_REV PF03978.13 GAX24862.1 - 0.071 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF3419 PF11899.8 GAX24863.1 - 2.2e-69 234.5 0.0 6.2e-69 233.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 GAX24863.1 - 6.7e-16 58.6 0.0 1.6e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX24863.1 - 4e-08 33.9 0.0 8.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX24863.1 - 3.2e-07 30.9 0.0 9e-06 26.3 0.0 3.1 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX24863.1 - 3.4e-07 29.8 0.0 5.9e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GAX24863.1 - 9e-06 26.3 0.0 3.3e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX24863.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP2C PF00481.21 GAX24864.1 - 1.4e-49 169.1 0.1 2.7e-49 168.1 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Ank_2 PF12796.7 GAX24864.1 - 5.4e-07 30.1 0.0 1.6e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX24864.1 - 1.7e-06 28.2 0.8 0.045 14.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 GAX24864.1 - 1e-05 26.0 0.0 2.9e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX24864.1 - 2.4e-05 24.4 0.2 0.65 10.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat PP2C_2 PF13672.6 GAX24864.1 - 7.8e-05 22.4 0.7 0.00028 20.6 0.7 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Ank_5 PF13857.6 GAX24864.1 - 0.00017 21.8 0.1 0.028 14.8 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) R3H-assoc PF13902.6 GAX24865.1 - 0.016 15.6 2.3 0.071 13.5 2.3 2.0 1 1 0 1 1 1 0 R3H-associated N-terminal domain MGDG_synth PF06925.11 GAX24866.1 - 1.3e-23 84.0 0.0 1.9e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 GAX24866.1 - 4.3e-11 43.1 0.3 1.2e-07 31.8 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 GAX24866.1 - 0.00016 21.3 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX24866.1 - 0.0006 20.3 0.3 0.002 18.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX24866.1 - 0.14 12.2 0.0 0.61 10.1 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase Family 4 DUF4834 PF16118.5 GAX24867.1 - 0.082 13.9 0.2 3.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Med13_C PF06333.12 GAX24867.1 - 1.6 7.9 6.4 8.9 5.5 0.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Arginosuc_synth PF00764.19 GAX24868.1 - 2.4e-152 507.7 0.0 2.9e-152 507.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 GAX24868.1 - 0.0032 17.0 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAX24868.1 - 0.0097 14.7 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase His_Phos_2 PF00328.22 GAX24869.1 - 5.4e-14 52.3 0.0 2.3e-11 43.7 0.0 2.3 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Phytase-like PF13449.6 GAX24870.1 - 6.2e-40 137.9 1.2 3.9e-39 135.3 0.1 2.5 3 0 0 3 3 3 1 Esterase-like activity of phytase SGL PF08450.12 GAX24870.1 - 0.0019 17.9 1.9 12 5.4 0.1 4.1 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region LOR PF04525.12 GAX24870.1 - 0.0091 15.6 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 2 LURP-one-related Cytochrom_D1 PF02239.16 GAX24870.1 - 0.016 13.8 1.1 0.062 11.8 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain LVIVD PF08309.11 GAX24870.1 - 0.11 11.8 7.0 7.1 6.0 0.0 4.8 4 0 0 4 4 4 0 LVIVD repeat NHL PF01436.21 GAX24870.1 - 0.14 12.3 0.7 65 3.8 0.1 4.3 4 0 0 4 4 4 0 NHL repeat TPR_17 PF13431.6 GAX24871.1 - 4e-08 33.1 0.4 0.55 10.7 0.0 5.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX24871.1 - 9.2e-08 31.6 3.5 0.3 11.3 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24871.1 - 2.9e-07 30.0 5.3 0.11 12.3 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX24871.1 - 4.1e-06 27.2 0.8 0.22 12.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX24871.1 - 2.5e-05 24.7 0.9 0.99 10.4 0.2 5.5 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX24871.1 - 2.6e-05 24.8 0.6 0.085 13.5 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX24871.1 - 9.3e-05 22.0 0.7 2.2 8.0 0.0 5.4 4 2 2 6 6 6 1 TPR repeat TPR_7 PF13176.6 GAX24871.1 - 0.0031 17.4 1.6 1.3 9.2 0.0 4.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX24871.1 - 0.0032 17.6 0.1 1 9.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX24871.1 - 0.0055 16.8 4.5 28 5.3 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX24871.1 - 0.016 14.6 0.1 0.17 11.2 0.1 2.2 2 0 0 2 2 2 0 MalT-like TPR region TPR_20 PF14561.6 GAX24871.1 - 0.043 14.1 0.5 4 7.8 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX24871.1 - 0.055 14.1 0.7 75 4.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Fae PF08714.11 GAX24871.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) TPR_12 PF13424.6 GAX24871.1 - 0.16 12.3 4.9 12 6.3 0.1 4.0 3 1 3 6 6 5 0 Tetratricopeptide repeat TAF1_subA PF14929.6 GAX24871.1 - 0.18 11.2 0.6 0.37 10.2 0.1 1.7 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A TPR_10 PF13374.6 GAX24871.1 - 0.2 11.6 1.0 9.2 6.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX24871.1 - 0.38 11.0 2.1 41 4.5 0.2 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF423 PF04241.15 GAX24872.1 - 8.8e-23 80.3 3.0 1.8e-22 79.3 3.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF423) OTU PF02338.19 GAX24872.1 - 4e-07 30.6 0.0 6.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease SLATT_fungal PF18142.1 GAX24872.1 - 0.34 10.9 4.5 0.22 11.5 1.6 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain DnaJ PF00226.31 GAX24873.1 - 1.4e-14 54.0 0.4 2.7e-14 53.0 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3561 PF12084.8 GAX24873.1 - 0.021 14.8 0.0 0.021 14.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3561) Aldo_ket_red PF00248.21 GAX24874.1 - 2.2e-48 165.0 0.0 2.5e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DNA_pol3_theta PF06440.11 GAX24874.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit DUF3754 PF12576.8 GAX24876.1 - 8.5e-26 90.5 0.0 1.4e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) Zn_clus PF00172.18 GAX24877.1 - 4.3e-09 36.4 10.3 7.1e-09 35.7 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_C_2 PF16899.5 GAX24878.1 - 0.00045 20.6 0.0 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 GAX24878.1 - 0.00052 19.8 0.2 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Lactate_perm PF02652.14 GAX24879.1 - 1.9e-67 228.2 33.0 8.6e-35 120.4 5.4 2.0 2 0 0 2 2 2 2 L-lactate permease Rubredoxin PF00301.20 GAX24880.1 - 1.2e-17 63.6 1.4 2e-17 62.9 1.4 1.3 1 0 0 1 1 1 1 Rubredoxin zf-C2H2_3 PF13878.6 GAX24880.1 - 0.089 12.6 0.7 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO PHD_4 PF16866.5 GAX24880.1 - 0.1 12.7 1.8 0.2 11.8 1.8 1.7 1 1 0 1 1 1 0 PHD-finger Rubredoxin_2 PF18073.1 GAX24880.1 - 0.21 11.4 1.9 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain AIM24 PF01987.17 GAX24882.1 - 1.1e-61 208.2 2.1 1.3e-61 207.9 2.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF2917 PF11142.8 GAX24882.1 - 0.2 11.0 0.5 20 4.7 0.1 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2917) RNase_Zc3h12a PF11977.8 GAX24883.1 - 2.3e-10 40.5 0.0 9.1e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF4442 PF14539.6 GAX24885.1 - 3e-19 69.4 0.1 3.9e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) YiiD_C PF09500.10 GAX24885.1 - 0.057 13.2 0.1 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) Glyco_hydro2_C5 PF18565.1 GAX24885.1 - 0.09 12.6 0.1 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 DnaJ PF00226.31 GAX24887.1 - 1.5e-15 57.1 2.8 3.1e-15 56.0 2.8 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 GAX24887.1 - 6.6e-10 38.8 0.7 1.7e-07 30.9 0.0 3.6 3 1 0 3 3 3 1 X-domain of DnaJ-containing Band_3_cyto PF07565.13 GAX24887.1 - 0.034 14.0 0.9 0.047 13.5 0.4 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain UBA PF00627.31 GAX24888.1 - 0.084 12.8 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 UBA/TS-N domain sCache_like PF16736.5 GAX24888.1 - 0.088 12.9 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Single Cache-like Aldo_ket_red PF00248.21 GAX24889.1 - 4.5e-46 157.4 0.1 8.7e-46 156.4 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family DnaJ PF00226.31 GAX24890.1 - 3.4e-24 84.7 0.4 5.8e-24 84.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Rick_17kDa_Anti PF05433.15 GAX24890.1 - 0.0026 17.6 1.8 0.0059 16.4 1.8 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Transgly_assoc PF04226.13 GAX24890.1 - 0.0027 17.9 3.9 0.0045 17.2 3.9 1.3 1 0 0 1 1 1 1 Transglycosylase associated protein Gly-zipper_Omp PF13488.6 GAX24890.1 - 0.042 13.9 2.3 0.078 13.0 2.3 1.4 1 0 0 1 1 1 0 Glycine zipper ATP-synt_ab PF00006.25 GAX24891.1 - 7.2e-103 342.8 0.0 1.1e-102 342.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAX24891.1 - 3e-36 123.9 0.0 5.4e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAX24891.1 - 1.7e-14 54.0 1.9 2.8e-14 53.4 0.2 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Imm9 PF15587.6 GAX24891.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 9 Form_Nir_trans PF01226.17 GAX24892.1 - 1.1e-69 234.4 25.7 1.4e-69 234.1 25.7 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter CYYR1 PF10873.8 GAX24892.1 - 5.5 7.4 7.8 3.5 8.1 1.6 2.4 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 TFIIF_beta PF02270.15 GAX24893.1 - 6.2e-20 71.1 0.0 1e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 GAX24893.1 - 9.3e-11 42.6 0.3 1.7e-10 41.7 0.3 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus Cyanate_lyase PF02560.14 GAX24897.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain Rhodanese PF00581.20 GAX24898.1 - 0.00012 22.5 0.0 0.00053 20.5 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain Pribosyltran_N PF13793.6 GAX24899.1 - 2.1e-38 130.8 0.4 7.9e-38 129.0 0.0 2.2 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAX24899.1 - 1.1e-16 61.4 0.0 1.6e-15 57.7 0.0 2.3 1 1 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAX24899.1 - 1.1e-11 44.5 0.0 5.8e-11 42.2 0.0 2.1 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAX24899.1 - 0.00021 20.8 0.0 0.0005 19.6 0.0 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 GAX24899.1 - 0.028 13.9 0.3 0.07 12.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyl transferase NTF2 PF02136.20 GAX24900.1 - 6.2e-08 33.2 1.0 8.9e-07 29.5 1.0 2.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GAX24900.1 - 6.9e-07 29.0 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_kinase PF00696.28 GAX24901.1 - 4.1e-23 82.2 0.0 8.1e-23 81.3 0.0 1.5 1 1 0 1 1 1 1 Amino acid kinase family BES1_N PF05687.13 GAX24901.1 - 0.014 15.8 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal TFA2_Winged_2 PF18121.1 GAX24901.1 - 0.016 14.9 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 ADPrib_exo_Tox PF03496.14 GAX24901.1 - 0.063 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Cdh1_DBD_1 PF18196.1 GAX24902.1 - 0.33 11.3 9.8 0.11 12.9 7.2 1.4 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 ATP_bind_3 PF01171.20 GAX24903.1 - 5.4e-43 146.9 0.3 9.9e-43 146.0 0.3 1.4 1 0 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 GAX24903.1 - 0.016 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Peptidase_S9 PF00326.21 GAX24904.1 - 6.4e-50 169.6 0.1 1e-49 168.9 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 GAX24904.1 - 1.9e-14 53.3 0.0 1.7e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 GAX24904.1 - 0.084 12.1 0.0 0.96 8.7 0.0 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 GST_C_2 PF13410.6 GAX24905.1 - 2.2e-11 43.6 0.0 4.9e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAX24905.1 - 1.4e-09 38.2 0.0 3.9e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAX24905.1 - 1.2e-07 31.8 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX24905.1 - 0.0027 17.9 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pirin PF02678.16 GAX24906.1 - 5.5e-15 55.3 3.2 5e-13 49.0 3.2 2.4 1 1 0 1 1 1 1 Pirin Pirin_C PF05726.13 GAX24906.1 - 5.5e-15 55.6 0.0 2e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain NAGidase PF07555.13 GAX24906.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase ATP-grasp_3 PF02655.14 GAX24907.1 - 8.2e-09 35.7 0.0 6.9e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GAX24907.1 - 7.5e-05 22.3 0.0 0.00019 21.0 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 GAX24907.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus Tricorn_C1 PF14684.6 GAX24908.1 - 1.3e-23 82.9 1.1 2.4e-23 82.0 1.1 1.5 1 0 0 1 1 1 1 Tricorn protease C1 domain Peptidase_S41 PF03572.18 GAX24908.1 - 1.6e-19 70.1 0.0 2.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GAX24908.1 - 8.8e-08 31.9 0.1 8.8e-08 31.9 0.1 2.0 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 GAX24908.1 - 3.3e-05 23.8 0.0 8.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 GAX24908.1 - 7.8e-05 22.9 0.0 0.00029 21.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX24908.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Ank_2 PF12796.7 GAX24910.1 - 1.1e-15 57.9 3.4 7.9e-06 26.4 3.2 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX24910.1 - 6.4e-12 44.6 3.6 0.36 11.5 0.0 6.5 6 1 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 GAX24910.1 - 3.1e-11 43.5 8.7 0.00066 20.2 0.5 5.1 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAX24910.1 - 9.2e-09 35.4 3.6 0.38 11.3 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAX24910.1 - 2.2e-07 31.0 7.2 0.37 11.2 0.6 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) ATP_bind_1 PF03029.17 GAX24911.1 - 2e-73 247.2 0.0 1.4e-71 241.1 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 GAX24911.1 - 0.00042 20.6 0.0 0.0013 19.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 GAX24911.1 - 0.0028 17.4 0.0 0.084 12.6 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 GAX24911.1 - 0.003 18.0 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 GAX24911.1 - 0.0055 17.2 0.0 0.018 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 GAX24911.1 - 0.008 15.8 0.0 4.1 7.0 0.0 2.7 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAX24911.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAX24911.1 - 0.017 15.0 0.0 21 5.0 0.0 3.6 3 1 1 4 4 4 0 RsgA GTPase T2SSE PF00437.20 GAX24911.1 - 0.046 12.8 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 GAX24911.1 - 0.067 13.6 0.0 0.26 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 GAX24911.1 - 0.12 12.4 0.2 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Adenylate kinase AAA_33 PF13671.6 GAX24911.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAX24911.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_31 PF13614.6 GAX24911.1 - 0.2 11.5 0.3 1.9 8.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain TAXi_N PF14543.6 GAX24912.1 - 7.8e-18 65.3 0.9 1.3e-17 64.6 0.9 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX24912.1 - 1.1e-14 54.6 0.0 3.4e-09 36.6 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX24912.1 - 3.3e-08 33.5 0.0 5.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal GH115_C PF17829.1 GAX24912.1 - 0.2 11.5 0.7 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 Gylcosyl hydrolase family 115 C-terminal domain CN_hydrolase PF00795.22 GAX24913.1 - 3.7e-35 121.5 1.0 3.2e-16 59.5 0.1 2.8 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase RasGAP_C PF03836.15 GAX24914.1 - 0.00091 19.4 2.0 0.00091 19.4 2.0 1.9 1 1 1 2 2 2 1 RasGAP C-terminus zf-CpG_bind_C PF12269.8 GAX24914.1 - 0.25 11.1 10.7 1.7 8.3 2.2 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain MCCD1 PF15707.5 GAX24914.1 - 0.35 11.4 13.4 0.23 12.0 2.0 2.6 1 1 1 2 2 2 0 Mitochondrial coiled-coil domain protein 1 7TMR-HDED PF07697.11 GAX24914.1 - 4.4 7.4 12.0 7 6.7 12.0 1.4 1 1 0 1 1 1 0 7TM-HD extracellular YabA PF06156.13 GAX24914.1 - 6 7.6 11.2 0.98 10.1 2.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 GAX24914.1 - 6.4 5.8 10.8 14 4.6 10.7 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0449 PF15136.6 GAX24914.1 - 7.1 7.2 9.4 6.2 7.3 0.1 3.6 2 1 3 5 5 5 0 Uncharacterised protein family UPF0449 Exonuc_VII_L PF02601.15 GAX24914.1 - 8.8 5.8 11.1 20 4.7 11.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit HlyIII PF03006.20 GAX24915.1 - 6.3e-35 120.9 15.2 7.4e-35 120.7 15.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related VIT1 PF01988.19 GAX24915.1 - 1.3 8.9 4.2 3.2 7.6 4.2 1.6 1 0 0 1 1 1 0 VIT family tRNA-synt_2d PF01409.20 GAX24916.1 - 8.2e-59 199.0 0.1 1.2e-58 198.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 GAX24916.1 - 1.2e-24 86.5 0.0 3.3e-24 85.1 0.0 1.7 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain DENN PF02141.21 GAX24917.1 - 1.1e-30 107.0 0.6 2.1e-30 106.1 0.6 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAX24917.1 - 3.9e-14 53.1 1.9 7.5e-13 49.0 0.4 3.0 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 GAX24917.1 - 6.7e-09 35.6 0.5 1.4e-07 31.3 0.0 2.9 3 0 0 3 3 3 1 dDENN domain SpoIIP PF07454.11 GAX24917.1 - 0.7 9.3 2.0 1.1 8.6 2.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DCP2 PF05026.13 GAX24918.1 - 8.2e-22 77.3 1.1 1.9e-21 76.1 1.1 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 GAX24918.1 - 3.3e-13 49.8 0.0 7.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain C2 PF00168.30 GAX24919.1 - 4.7e-26 91.1 0.0 5.4e-13 49.1 0.0 3.7 4 0 0 4 4 4 2 C2 domain Acetyltransf_17 PF17668.1 GAX24919.1 - 0.038 14.8 0.2 0.092 13.6 0.2 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain eIF3_subunit PF08597.10 GAX24919.1 - 4.9 7.0 12.6 4 7.3 0.1 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF1115 PF06544.12 GAX24919.1 - 8.9 6.4 10.6 7 6.7 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) SSF PF00474.17 GAX24920.1 - 7.5e-17 61.3 28.1 7.5e-17 61.3 28.1 2.2 2 0 0 2 2 2 1 Sodium:solute symporter family RAMP4 PF06624.12 GAX24920.1 - 4.9 7.3 5.8 0.44 10.6 0.6 2.0 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 SSF PF00474.17 GAX24921.1 - 1.1e-14 54.1 21.0 1.3e-14 53.9 17.2 2.2 2 0 0 2 2 2 2 Sodium:solute symporter family Ras PF00071.22 GAX24922.1 - 5e-64 214.8 0.1 6e-64 214.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX24922.1 - 6.7e-36 123.1 0.1 9.6e-36 122.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX24922.1 - 2.6e-18 66.1 0.1 3.2e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAX24922.1 - 5.5e-07 29.2 0.1 6.8e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX24922.1 - 3.3e-06 26.8 0.3 7.6e-06 25.6 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAX24922.1 - 0.00042 19.8 0.1 0.00053 19.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX24922.1 - 0.00069 19.7 0.1 0.001 19.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX24922.1 - 0.0023 17.9 0.1 1.2 9.0 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 GAX24922.1 - 0.033 14.0 0.1 0.092 12.5 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 GAX24922.1 - 0.082 12.6 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAX24922.1 - 0.089 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 GAX24922.1 - 0.09 12.3 0.0 0.34 10.4 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 GAX24922.1 - 0.16 12.2 0.0 0.35 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Hydrolase_like PF13242.6 GAX24923.1 - 3e-13 49.6 0.0 6.1e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 GAX24923.1 - 1.1e-11 44.8 0.0 3.8e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX24923.1 - 3e-10 40.5 0.0 1.3e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX24923.1 - 1.4e-09 38.6 0.0 2.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Syja_N PF02383.18 GAX24924.1 - 0.043 13.1 0.2 1.8 7.8 0.5 2.2 1 1 1 2 2 2 0 SacI homology domain BLOC1S3 PF15753.5 GAX24924.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4743 PF15916.5 GAX24926.1 - 0.14 12.1 1.9 0.33 10.9 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) DcpS_C PF11969.8 GAX24927.1 - 7.4e-20 71.5 0.3 1.5e-19 70.5 0.3 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TPR_12 PF13424.6 GAX24928.1 - 2.5e-60 200.7 19.7 9.3e-12 45.1 0.1 9.3 7 1 3 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 GAX24928.1 - 2.1e-55 183.2 14.1 2.5e-09 36.7 0.6 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 GAX24928.1 - 3.6e-41 137.3 11.8 7e-05 22.5 0.1 12.5 12 1 1 13 13 13 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAX24928.1 - 2.6e-40 133.3 15.2 0.00039 20.3 1.0 12.0 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_8 PF13181.6 GAX24928.1 - 2.7e-27 92.6 17.6 0.00064 19.7 0.1 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX24928.1 - 1.9e-22 80.1 2.4 3e-10 40.0 1.1 4.9 3 1 2 5 5 5 4 MalT-like TPR region TPR_7 PF13176.6 GAX24928.1 - 1e-20 72.2 16.4 0.013 15.4 0.0 11.1 11 1 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAX24928.1 - 2.5e-20 71.4 14.1 0.28 12.1 0.2 12.2 10 2 2 12 12 12 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX24928.1 - 1e-17 63.5 11.4 0.0016 18.1 0.0 9.6 11 0 0 11 11 11 5 TPR repeat TPR_16 PF13432.6 GAX24928.1 - 1.7e-09 38.2 22.9 0.038 14.6 0.2 8.7 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX24928.1 - 3.8e-09 36.6 15.6 6.9 7.5 0.0 11.5 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX24928.1 - 6.5e-08 32.5 0.4 12 6.9 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat SNAP PF14938.6 GAX24928.1 - 5.4e-07 29.3 15.5 0.00013 21.5 0.0 5.7 4 1 2 7 7 7 4 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 GAX24928.1 - 3.6e-06 27.4 15.5 0.32 11.5 0.2 8.6 7 3 1 9 9 9 1 Tetratricopeptide repeat DUF2225 PF09986.9 GAX24928.1 - 0.00019 21.2 3.6 5.6 6.6 0.1 5.0 2 1 2 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 GAX24928.1 - 0.00063 19.9 0.1 14 6.4 0.0 6.6 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAX24928.1 - 0.0013 18.0 7.5 0.89 8.7 0.0 5.9 4 3 2 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 GAX24928.1 - 0.01 15.9 25.4 2.4 8.3 0.0 8.9 8 2 2 10 10 10 0 MIT (microtubule interacting and transport) domain CHASE3 PF05227.13 GAX24928.1 - 0.13 12.2 1.3 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 CHASE3 domain DUF3856 PF12968.7 GAX24928.1 - 0.16 12.0 11.7 0.27 11.3 0.0 5.3 5 2 1 7 7 7 0 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 GAX24928.1 - 0.19 11.4 14.7 43 3.7 0.0 6.9 5 2 1 7 7 7 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 GAX24928.1 - 0.21 11.2 17.4 0.46 10.2 0.1 6.7 3 1 2 6 6 6 0 26S proteasome subunit RPN7 DUF4810 PF16068.5 GAX24928.1 - 0.23 12.0 6.0 12 6.5 0.1 4.4 5 0 0 5 5 3 0 Domain of unknown function (DUF4810) SRP68 PF16969.5 GAX24929.1 - 2e-64 218.6 17.1 7.3e-60 203.5 17.1 3.0 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 MIT PF04212.18 GAX24929.1 - 0.0092 16.0 0.2 0.089 12.9 0.0 2.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DASH_Dad3 PF08656.10 GAX24929.1 - 0.061 13.4 0.4 0.65 10.1 0.1 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 Chloroa_b-bind PF00504.21 GAX24930.1 - 1.5e-33 116.6 0.0 2e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RRM_1 PF00076.22 GAX24931.1 - 5.3e-06 26.2 0.0 0.00015 21.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX24931.1 - 0.044 13.9 0.0 0.25 11.5 0.0 2.3 3 0 0 3 3 3 0 RNA recognition motif PRC2_HTH_1 PF18118.1 GAX24931.1 - 8.9 7.2 6.7 18 6.2 1.4 3.2 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Ribosomal_L1 PF00687.21 GAX24932.1 - 1.2e-28 100.3 0.0 1.6e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NYN_YacP PF05991.11 GAX24932.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 YacP-like NYN domain adh_short PF00106.25 GAX24933.1 - 1.3e-27 96.5 0.0 4e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX24933.1 - 5.7e-19 68.6 0.0 3.5e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX24933.1 - 0.0032 17.4 0.2 0.0052 16.7 0.2 1.4 1 1 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 GAX24933.1 - 0.087 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 GAX24933.1 - 0.15 11.5 0.1 0.36 10.2 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX24933.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NIF PF03031.18 GAX24934.1 - 2.5e-15 56.6 0.0 3.4e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAX24934.1 - 0.00012 22.5 0.8 0.23 11.9 0.1 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 GAX24934.1 - 0.0051 16.5 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Acid_phosphat_B PF03767.14 GAX24934.1 - 0.16 11.6 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ADH_zinc_N_2 PF13602.6 GAX24935.1 - 6.7e-05 24.0 0.0 0.00018 22.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAX24935.1 - 0.00033 20.6 0.0 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX24935.1 - 0.0074 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.28 GAX24936.1 - 6.2e-34 118.3 0.4 7.9e-34 118.0 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 GAX24936.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF2389 PF09493.10 GAX24937.1 - 2.5e-14 53.7 2.7 3.7e-14 53.1 2.7 1.3 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) DUF1356 PF07092.12 GAX24937.1 - 0.16 11.2 1.2 9.8 5.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 GAX24937.1 - 0.39 10.7 11.1 0.83 9.7 2.0 3.1 2 2 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Adaptin_N PF01602.20 GAX24938.1 - 0.00026 19.7 3.7 0.00065 18.4 0.3 3.0 3 0 0 3 3 3 1 Adaptin N terminal region Paramyx_P_V_C PF03210.13 GAX24938.1 - 0.019 14.7 0.2 0.052 13.3 0.2 1.7 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Glyoxalase PF00903.25 GAX24939.1 - 1.8e-08 34.7 0.0 5.2e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAX24939.1 - 9e-05 22.7 0.0 0.00025 21.3 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AP_endonuc_2 PF01261.24 GAX24939.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Rhodanese PF00581.20 GAX24940.1 - 0.00012 22.5 0.0 0.00024 21.6 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain DUF285 PF03382.14 GAX24942.1 - 6.4e-59 197.0 21.5 1.1e-34 118.7 3.7 2.2 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 F-box_4 PF15966.5 GAX24942.1 - 0.061 13.2 0.5 13 5.7 0.0 2.6 2 1 0 2 2 2 0 F-box DUF1329 PF07044.11 GAX24942.1 - 0.11 11.7 0.8 0.22 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1329) TMEM164 PF14808.6 GAX24943.1 - 0.06 12.7 7.2 0.22 10.9 7.2 1.8 1 1 0 1 1 1 0 TMEM164 family Aminotran_1_2 PF00155.21 GAX24944.1 - 4.8e-59 200.4 0.0 5.8e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAX24944.1 - 5.6e-07 28.4 0.0 1.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 GAX24944.1 - 0.0021 16.7 0.0 0.0028 16.3 0.0 1.3 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 GAX24944.1 - 0.0028 16.7 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V ATP-grasp_5 PF13549.6 GAX24944.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Aminotran_MocR PF12897.7 GAX24944.1 - 0.077 11.8 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase GOLD_2 PF13897.6 GAX24945.1 - 0.55 10.7 0.1 0.55 10.7 0.1 2.9 3 1 0 4 4 4 0 Golgi-dynamics membrane-trafficking DUF2894 PF11445.8 GAX24945.1 - 0.75 10.2 6.3 2.7 8.4 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) PTS_IIA PF02255.16 GAX24945.1 - 1.2 9.2 6.5 3.6 7.7 6.5 1.8 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Get5_C PF18514.1 GAX24945.1 - 1.8 8.4 4.4 0.88 9.3 0.2 2.6 3 0 0 3 3 3 0 Get5 C-terminal domain WD40 PF00400.32 GAX24946.1 - 0.0086 16.9 0.3 2.3 9.2 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX24946.1 - 0.17 12.2 0.0 0.94 9.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TLC PF03219.14 GAX24947.1 - 1.4e-06 27.3 2.1 4.5e-05 22.4 0.1 2.4 1 1 1 2 2 2 2 TLC ATP/ADP transporter CDC45 PF02724.14 GAX24947.1 - 0.071 11.4 0.0 0.14 10.4 0.0 1.4 2 0 0 2 2 2 0 CDC45-like protein DUF1418 PF07214.12 GAX24947.1 - 0.086 12.7 0.1 20 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) FAM76 PF16046.5 GAX24948.1 - 3.3e-05 23.4 10.3 3.3e-05 23.4 10.3 5.1 3 1 1 5 5 5 2 FAM76 protein DUF4370 PF14290.6 GAX24948.1 - 0.00023 21.1 0.4 0.00063 19.7 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4370) TMF_DNA_bd PF12329.8 GAX24948.1 - 0.00036 20.5 13.6 0.00036 20.5 13.6 9.3 7 3 3 10 10 10 1 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 GAX24948.1 - 0.017 15.0 1.3 0.017 15.0 1.3 5.3 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor LPP PF04728.13 GAX24948.1 - 0.18 12.2 26.7 13 6.2 1.8 7.6 5 1 0 6 6 6 0 Lipoprotein leucine-zipper GAS PF13851.6 GAX24948.1 - 0.56 9.5 100.0 0.0076 15.6 21.9 7.0 3 2 3 6 6 6 0 Growth-arrest specific micro-tubule binding DUF5494 PF17598.2 GAX24949.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5494) 2-oxoacid_dh PF00198.23 GAX24950.1 - 7e-60 202.4 0.0 1.1e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX24950.1 - 1.6e-35 120.7 13.6 1.2e-18 66.7 5.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 GAX24950.1 - 2e-28 98.4 2.4 2.3e-15 56.6 0.1 2.9 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAX24950.1 - 2.7e-05 23.9 0.1 0.38 10.6 0.0 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 GAX24950.1 - 2.7e-05 24.8 6.3 0.36 11.5 0.3 4.7 3 2 1 4 4 4 2 HlyD family secretion protein QRPTase_N PF02749.16 GAX24950.1 - 0.00039 20.4 0.4 0.78 9.8 0.0 3.9 3 1 1 4 4 4 2 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 GAX24950.1 - 0.00065 19.6 2.1 0.24 11.3 0.3 2.4 2 0 0 2 2 2 2 Glycine cleavage H-protein DUF2118 PF09891.9 GAX24950.1 - 0.039 13.9 0.1 2.1 8.3 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PYNP_C PF07831.13 GAX24950.1 - 0.072 12.8 0.3 15 5.3 0.1 3.1 2 1 1 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain FabA PF07977.13 GAX24951.1 - 1.6e-32 112.0 0.0 2.5e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 GAX24951.1 - 0.0081 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain IlvC PF01450.19 GAX24952.1 - 4.1e-42 143.9 0.2 1.5e-32 112.8 0.1 2.4 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 GAX24952.1 - 9.3e-34 116.4 0.0 1.8e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1877 PF08974.10 GAX24952.1 - 0.0073 16.4 0.1 0.013 15.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) CbiJ PF02571.14 GAX24952.1 - 0.05 13.1 0.0 0.59 9.6 0.0 2.4 3 0 0 3 3 3 0 Precorrin-6x reductase CbiJ/CobK SSL_OB PF09199.10 GAX24952.1 - 0.15 12.4 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 Staphylococcal superantigen-like OB-fold domain Got1 PF04178.12 GAX24953.1 - 3.4e-10 40.3 7.9 5.3e-10 39.7 7.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Radical_SAM PF04055.21 GAX24954.1 - 5.4e-08 33.4 0.5 1.5e-06 28.7 0.3 2.8 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 GAX24954.1 - 0.0004 20.5 0.1 0.0015 18.7 0.1 1.9 1 1 0 1 1 1 1 4Fe-4S single cluster domain VPS28 PF03997.12 GAX24954.1 - 0.0028 17.4 0.1 0.0061 16.3 0.1 1.5 1 0 0 1 1 1 1 VPS28 protein YjcB PF15940.5 GAX24954.1 - 0.17 12.0 1.7 20 5.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function Pkinase PF00069.25 GAX24955.1 - 4.5e-06 26.2 0.0 7.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 GAX24955.1 - 0.044 13.1 0.1 0.13 11.5 0.1 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase AAA_5 PF07728.14 GAX24956.1 - 1.9e-105 348.6 0.6 4.5e-17 62.3 0.0 9.3 9 1 0 9 9 8 8 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 GAX24956.1 - 1.9e-22 79.6 0.0 0.035 14.2 0.0 7.3 6 1 0 6 6 6 5 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 GAX24956.1 - 2e-20 73.5 0.0 0.00069 20.0 0.0 6.4 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX24956.1 - 4.2e-20 72.8 13.1 1.6e-05 25.3 0.3 6.8 6 0 0 6 6 5 5 AAA ATPase domain AAA_3 PF07726.11 GAX24956.1 - 7.7e-19 67.9 0.0 8.3e-12 45.1 0.0 6.6 7 0 0 7 7 5 1 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 GAX24956.1 - 7.8e-19 67.7 0.0 4.3e-18 65.3 0.0 2.5 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_lid_7 PF17867.1 GAX24956.1 - 1.1e-18 67.4 2.0 7.4e-08 32.5 0.2 5.4 5 0 0 5 5 4 2 Midasin AAA lid domain AAA_7 PF12775.7 GAX24956.1 - 1.2e-17 64.0 0.5 5.8e-05 22.7 0.1 5.8 6 0 0 6 6 5 4 P-loop containing dynein motor region AAA_18 PF13238.6 GAX24956.1 - 3.1e-15 56.8 0.3 0.029 14.9 0.0 6.4 5 0 0 5 5 5 4 AAA domain TsaE PF02367.17 GAX24956.1 - 2.6e-14 53.3 1.0 0.16 12.0 0.0 5.6 5 0 0 5 5 5 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 GAX24956.1 - 5.1e-13 49.5 4.6 0.056 13.7 0.0 6.7 6 0 0 6 6 5 3 AAA domain AAA_14 PF13173.6 GAX24956.1 - 9.2e-13 48.4 0.0 0.061 13.4 0.0 7.0 6 0 0 6 6 6 2 AAA domain Sigma54_activat PF00158.26 GAX24956.1 - 3e-12 46.6 0.0 0.26 11.0 0.0 5.7 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_30 PF13604.6 GAX24956.1 - 5.9e-12 45.7 0.1 0.023 14.4 0.0 7.0 6 1 0 6 6 6 2 AAA domain AAA_33 PF13671.6 GAX24956.1 - 7.4e-11 42.4 1.1 0.37 10.9 0.1 5.7 5 0 0 5 5 5 3 AAA domain RsgA_GTPase PF03193.16 GAX24956.1 - 2e-10 40.9 0.1 0.6 10.0 0.0 5.6 5 0 0 5 5 5 2 RsgA GTPase AAA_29 PF13555.6 GAX24956.1 - 2.4e-10 40.0 0.2 0.39 10.5 0.0 5.6 5 0 0 5 5 5 2 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX24956.1 - 3.2e-10 40.6 6.3 0.0059 17.1 0.0 6.5 6 0 0 6 6 5 2 ABC transporter NACHT PF05729.12 GAX24956.1 - 9.4e-10 38.7 0.4 0.12 12.2 0.0 5.5 6 0 0 6 6 4 3 NACHT domain Zeta_toxin PF06414.12 GAX24956.1 - 2.7e-09 36.6 0.0 0.32 10.2 0.0 5.0 5 0 0 5 5 4 2 Zeta toxin AAA_28 PF13521.6 GAX24956.1 - 6.6e-09 36.2 5.3 0.3 11.3 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA_6 PF12774.7 GAX24956.1 - 9.8e-09 34.6 1.9 0.66 8.9 0.0 7.1 7 0 0 7 7 7 1 Hydrolytic ATP binding site of dynein motor region Mg_chelatase PF01078.21 GAX24956.1 - 1.1e-07 31.4 2.0 2.1 7.6 0.1 7.8 7 1 0 7 7 7 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 GAX24956.1 - 1.3e-07 31.0 0.2 2.7 7.0 0.0 4.8 5 0 0 5 5 5 2 Type II/IV secretion system protein RNA_helicase PF00910.22 GAX24956.1 - 4.5e-07 30.2 0.0 6.1 7.3 0.0 5.7 5 0 0 5 5 5 0 RNA helicase DUF815 PF05673.13 GAX24956.1 - 4.8e-07 29.2 0.2 0.12 11.5 0.0 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 GAX24956.1 - 7.8e-07 29.3 0.2 0.028 14.5 0.0 4.9 5 0 0 5 5 3 1 Sigma-54 interaction domain Rad17 PF03215.15 GAX24956.1 - 3.1e-06 27.2 2.5 0.95 9.4 0.1 5.7 6 0 0 6 6 5 1 Rad17 P-loop domain AAA_25 PF13481.6 GAX24956.1 - 6.2e-06 25.9 3.8 0.63 9.6 0.0 5.6 6 0 0 6 6 6 2 AAA domain SRP54 PF00448.22 GAX24956.1 - 9.3e-06 25.4 0.0 1.6 8.4 0.0 4.9 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 GAX24956.1 - 1.4e-05 25.1 2.8 11 6.1 0.0 6.1 6 0 0 6 6 5 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 GAX24956.1 - 2e-05 24.4 0.2 5.4 6.7 0.0 4.6 5 0 0 5 5 4 0 IstB-like ATP binding protein ATPase_2 PF01637.18 GAX24956.1 - 2.3e-05 24.4 0.0 6.5 6.6 0.0 5.3 5 0 0 5 5 5 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 GAX24956.1 - 3.3e-05 23.7 0.1 1.8 8.3 0.0 4.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase VWA_2 PF13519.6 GAX24956.1 - 4.1e-05 24.2 0.0 0.00015 22.4 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Roc PF08477.13 GAX24956.1 - 4.1e-05 23.8 0.4 4.8 7.4 0.0 5.3 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 GAX24956.1 - 0.00018 21.5 4.1 5.5 6.9 0.0 5.0 5 0 0 5 5 4 0 NTPase AAA_23 PF13476.6 GAX24956.1 - 0.00035 21.1 30.7 0.0078 16.7 0.0 7.7 7 0 0 7 7 5 2 AAA domain RuvB_N PF05496.12 GAX24956.1 - 0.00039 20.2 1.4 1.4 8.7 0.1 5.4 5 1 0 5 5 5 1 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 GAX24956.1 - 0.0011 18.5 1.7 9.4 5.8 0.0 4.3 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 GAX24956.1 - 0.0025 17.3 0.0 3.7 6.9 0.0 4.3 5 0 0 5 5 5 0 Bacterial TniB protein PduV-EutP PF10662.9 GAX24956.1 - 0.0027 17.4 1.4 1.8 8.3 0.1 4.5 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 GAX24956.1 - 0.0032 17.8 8.5 1.3 9.3 0.0 5.8 6 0 0 6 6 5 1 AAA domain dNK PF01712.19 GAX24956.1 - 0.0032 17.4 1.6 4.6 7.0 0.0 4.4 5 0 0 5 5 4 0 Deoxynucleoside kinase CbiA PF01656.23 GAX24956.1 - 0.012 15.6 0.4 30 4.7 0.0 4.3 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.18 GAX24956.1 - 0.015 14.8 0.2 42 3.6 0.0 4.6 4 0 0 4 4 4 0 Ferrous iron transport protein B PRK PF00485.18 GAX24956.1 - 0.021 14.5 0.7 19 4.9 0.0 3.9 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 GAX24956.1 - 0.034 14.0 3.6 67 3.3 0.0 5.4 7 0 0 7 7 6 0 Chloramphenicol phosphotransferase-like protein AAA_21 PF13304.6 GAX24956.1 - 0.14 11.9 4.8 2 8.2 0.0 4.4 5 0 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 GAX24956.1 - 3.1 7.7 4.3 1.2e+02 2.6 0.1 4.2 5 0 0 5 5 4 0 Molybdopterin guanine dinucleotide synthesis protein B Thioredoxin_8 PF13905.6 GAX24957.1 - 3e-16 59.5 0.0 4.7e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX24957.1 - 0.00011 22.0 0.0 0.00072 19.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 GAX24957.1 - 0.00013 21.7 0.1 0.00019 21.2 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 GAX24957.1 - 0.0011 18.9 0.1 0.0038 17.2 0.2 1.8 2 1 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 GAX24957.1 - 0.0026 17.7 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 GAX24957.1 - 0.0033 17.9 0.0 0.0071 16.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF953 PF06110.11 GAX24957.1 - 0.052 13.2 0.1 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Na_H_antiporter PF03553.14 GAX24958.1 - 1.9e-40 139.0 26.8 2.1e-28 99.4 13.6 3.1 2 1 1 3 3 3 3 Na+/H+ antiporter family TSP_1 PF00090.19 GAX24959.1 - 3.3e-07 30.4 84.6 3.5e-05 23.9 5.6 6.6 6 0 0 6 6 6 5 Thrombospondin type 1 domain DUF2039 PF10217.9 GAX24960.1 - 8.8e-26 90.1 9.0 8.8e-26 90.1 9.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) TackOD1 PF18551.1 GAX24960.1 - 0.0089 15.7 3.3 0.017 14.8 3.3 1.4 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 RXT2_N PF08595.11 GAX24960.1 - 0.11 12.5 4.2 0.26 11.3 4.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 GAX24960.1 - 0.12 12.0 3.4 0.24 11.1 2.4 1.9 2 0 0 2 2 2 0 FAM176 family Zn_ribbon_SprT PF17283.2 GAX24960.1 - 0.2 11.6 0.2 0.2 11.6 0.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HypA PF01155.19 GAX24960.1 - 0.22 11.6 7.7 0.24 11.4 5.5 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Astro_capsid_p PF12226.8 GAX24960.1 - 1.1 8.4 6.5 1.5 7.9 6.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zinc-ribbons_6 PF07191.12 GAX24960.1 - 1.7 8.6 10.2 1 9.4 7.6 2.0 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_6 PF14599.6 GAX24960.1 - 1.9 8.5 8.9 32 4.7 0.0 2.5 1 1 1 2 2 2 0 Zinc-ribbon DZR PF12773.7 GAX24960.1 - 2.1 8.4 12.0 13 5.9 8.6 2.6 2 1 1 3 3 3 0 Double zinc ribbon PBP1_TM PF14812.6 GAX24960.1 - 3.2 8.2 17.4 0.33 11.4 11.1 2.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zinc_ribbon_2 PF13240.6 GAX24960.1 - 4.9 7.0 7.9 8.6 6.2 3.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Bestrophin PF01062.21 GAX24961.1 - 9.8e-21 74.4 0.7 1.3e-20 74.0 0.7 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ACR_tran PF00873.19 GAX24961.1 - 0.033 11.9 0.1 0.043 11.5 0.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF3165 PF11364.8 GAX24961.1 - 0.15 12.5 0.2 0.44 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) DUF5509 PF17625.2 GAX24961.1 - 0.2 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5509) Mito_carr PF00153.27 GAX24962.1 - 4.4e-16 58.6 0.9 7e-06 25.9 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 GAX24963.1 - 0.00028 20.7 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 GAX24963.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box Rhodanese PF00581.20 GAX24964.1 - 0.00058 20.3 0.0 0.0014 19.1 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain Pep_deformylase PF01327.21 GAX24965.1 - 3.4e-27 95.0 0.0 4.9e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Conotoxin PF02950.17 GAX24967.1 - 1 10.4 6.0 17 6.5 6.0 2.5 1 1 0 1 1 1 0 Conotoxin SASA PF03629.18 GAX24968.1 - 9.5e-26 90.8 0.0 1.4e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase HMG_box PF00505.19 GAX24969.1 - 5.3e-13 49.2 2.3 5.4e-08 33.1 0.5 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX24969.1 - 8.6e-08 32.7 0.2 7.2e-05 23.3 0.3 2.7 2 0 0 2 2 2 2 HMG-box domain OPA3 PF07047.12 GAX24971.1 - 4.1e-33 113.8 0.7 4.1e-33 113.8 0.7 1.7 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) APG6_N PF17675.1 GAX24971.1 - 0.0092 16.5 5.6 0.013 16.0 5.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF724 PF05266.14 GAX24971.1 - 0.05 13.4 5.9 0.08 12.8 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4094 PF13334.6 GAX24971.1 - 0.92 10.0 3.9 1.6 9.2 3.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4140 PF13600.6 GAX24971.1 - 2.1 8.9 6.9 11 6.6 6.9 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PA14 PF07691.12 GAX24972.1 - 0.053 13.3 0.1 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 PA14 domain PelD_GGDEF PF16963.5 GAX24972.1 - 0.075 12.8 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 PelD GGDEF domain Methyltransf_3 PF01596.17 GAX24973.1 - 1.8e-26 92.6 2.4 1.7e-18 66.6 1.8 3.4 2 1 0 2 2 2 2 O-methyltransferase UPF0176_N PF17773.1 GAX24973.1 - 4.7e-22 78.2 0.0 1.1e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAX24973.1 - 2.4e-14 53.5 7.7 4.6e-14 52.5 7.7 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal Methyltransf_24 PF13578.6 GAX24973.1 - 1e-06 29.7 0.1 8.4e-06 26.8 0.1 2.7 2 0 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.20 GAX24973.1 - 2e-06 28.3 0.0 9.3e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain PCMT PF01135.19 GAX24973.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Popeye PF04831.13 GAX24974.1 - 1.2e-07 31.9 0.2 2.1e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 GAX24974.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Redoxin PF08534.10 GAX24975.1 - 2.9e-25 88.7 0.0 3.5e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAX24975.1 - 3.4e-10 39.9 0.0 4.3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX24976.1 - 5.8e-05 22.8 0.0 6.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin TMEM144 PF07857.12 GAX24977.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters TraB PF01963.17 GAX24977.1 - 1.8 8.4 8.8 0.13 12.2 2.7 2.1 3 0 0 3 3 3 0 TraB family Phage_GPL PF05926.11 GAX24977.1 - 4.5 7.3 6.6 0.6 10.1 0.1 2.7 3 0 0 3 3 3 0 Phage head completion protein (GPL) SASP PF00269.20 GAX24978.1 - 0.013 15.5 0.5 0.034 14.1 0.5 1.7 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type GTP_EFTU PF00009.27 GAX24979.1 - 9.6e-34 116.6 0.0 9.6e-34 116.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAX24979.1 - 1.2e-18 67.1 0.0 5.1e-18 65.1 0.0 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 GAX24979.1 - 1.2e-16 60.3 0.2 6e-16 58.1 0.2 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 GAX24979.1 - 4e-08 33.3 0.9 3e-07 30.5 0.2 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAX24979.1 - 1.1e-05 25.8 0.2 1.1e-05 25.8 0.2 5.1 5 0 0 5 5 5 2 Elongation factor Tu domain 2 Roc PF08477.13 GAX24979.1 - 2.3e-05 24.6 0.0 0.0001 22.5 0.0 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX24979.1 - 0.0045 16.6 0.0 0.023 14.3 0.0 2.3 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.18 GAX24979.1 - 0.006 16.1 0.8 0.047 13.2 0.3 2.8 2 1 1 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX24979.1 - 0.011 15.6 4.4 0.5 10.3 0.7 3.3 1 1 2 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 GAX24979.1 - 0.019 15.2 0.2 0.086 13.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 GAX24979.1 - 0.057 13.2 1.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mon2_C PF16206.5 GAX24979.1 - 0.18 9.9 0.0 0.29 9.2 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of Mon2 protein AAA_16 PF13191.6 GAX24979.1 - 0.33 11.3 3.5 0.7 10.3 0.0 3.3 2 1 0 2 2 2 0 AAA ATPase domain RPAP1_N PF08621.10 GAX24980.1 - 0.007 16.1 9.2 0.52 10.1 0.2 2.6 2 0 0 2 2 2 2 RPAP1-like, N-terminal TetR_C_28 PF17937.1 GAX24980.1 - 0.018 15.5 2.5 0.38 11.2 1.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CitG PF01874.16 GAX24980.1 - 0.025 14.2 0.7 0.041 13.5 0.3 1.5 2 0 0 2 2 2 0 ATP:dephospho-CoA triphosphoribosyl transferase DUF4446 PF14584.6 GAX24980.1 - 1.7 8.6 4.6 2.4 8.1 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) T3SS_needle_F PF09392.10 GAX24980.1 - 2.7 8.3 6.2 4.5 7.5 3.6 2.8 2 1 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Rotamase_2 PF13145.6 GAX24980.1 - 3 8.7 8.7 0.53 11.1 2.1 2.3 1 1 0 2 2 2 0 PPIC-type PPIASE domain DUF4199 PF13858.6 GAX24980.1 - 3.9 7.9 11.1 3.9 7.9 3.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) FKBP_N PF01346.18 GAX24980.1 - 4.7 8.3 13.2 5.5 8.0 5.8 2.7 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TipAS PF07739.13 GAX24980.1 - 9.5 6.8 11.7 1e+03 0.3 11.3 3.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain PAP_fibrillin PF04755.12 GAX24981.1 - 2.7e-15 56.8 0.0 1.9e-08 34.5 0.0 2.6 2 1 0 2 2 2 2 PAP_fibrillin tRNA_edit PF04073.15 GAX24983.1 - 3.1e-09 37.0 0.0 4.9e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain FGGY_N PF00370.21 GAX24985.1 - 1.6e-13 50.8 0.0 1.8e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 GAX24985.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Hexokinase Sigma70_r2 PF04542.14 GAX24987.1 - 1.3e-11 44.0 0.0 3.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GAX24987.1 - 4.6e-09 35.7 1.5 5.2e-08 32.3 0.3 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 GAX24987.1 - 0.00052 20.1 0.1 0.079 13.1 0.0 3.6 3 1 0 3 3 3 1 Sigma-70 region 3 HTH_Crp_2 PF13545.6 GAX24987.1 - 0.003 17.5 1.2 3.6 7.6 0.0 3.5 3 0 0 3 3 3 2 Crp-like helix-turn-helix domain Sigma70_r1_2 PF00140.20 GAX24987.1 - 0.0097 15.9 0.9 0.024 14.6 0.2 2.0 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 HTH_15 PF12324.8 GAX24987.1 - 0.017 15.1 0.1 23 5.0 0.0 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase DprA_WH PF17782.1 GAX24987.1 - 0.058 13.5 0.9 0.55 10.4 0.1 2.8 2 0 0 2 2 2 0 DprA winged helix domain Peptidase_S9 PF00326.21 GAX24988.1 - 2e-41 141.8 0.0 2.8e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAX24988.1 - 1.2e-07 31.5 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAX24988.1 - 8e-05 22.0 0.0 0.00069 19.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX24988.1 - 0.0048 16.6 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAX24988.1 - 0.0056 16.8 0.0 0.063 13.4 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein COesterase PF00135.28 GAX24988.1 - 0.073 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family PhoPQ_related PF10142.9 GAX24988.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Myb_DNA-binding PF00249.31 GAX24992.1 - 3.3e-15 56.0 0.3 5.7e-15 55.2 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX24992.1 - 3.1e-05 24.2 0.0 5.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX24992.1 - 0.00015 21.6 0.1 0.00025 20.9 0.1 1.3 1 0 0 1 1 1 1 Myb DNA-binding like COX6A PF02046.15 GAX24994.1 - 4.7e-06 27.1 0.1 1.3e-05 25.7 0.1 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa Clathrin_lg_ch PF01086.17 GAX24995.1 - 4e-26 92.5 5.9 4.5e-26 92.3 5.9 1.1 1 0 0 1 1 1 1 Clathrin light chain AAA PF00004.29 GAX24996.1 - 5.1e-88 292.3 0.0 2.8e-45 154.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX24996.1 - 9.1e-26 89.4 5.3 5.2e-12 45.4 0.1 3.7 3 0 0 3 3 3 2 AAA+ lid domain AAA_2 PF07724.14 GAX24996.1 - 2.6e-14 53.7 0.1 2e-08 34.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX24996.1 - 1.2e-13 51.2 0.0 1.1e-07 32.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX24996.1 - 9.2e-13 48.9 0.0 2.5e-05 24.7 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 GAX24996.1 - 2.7e-12 46.7 0.0 2.4e-05 24.1 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_N PF02359.18 GAX24996.1 - 3.2e-11 43.3 0.0 1.7e-10 40.9 0.0 2.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.6 GAX24996.1 - 2e-10 41.0 0.0 0.00054 20.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 GAX24996.1 - 2.7e-10 40.0 0.0 7.7e-05 22.0 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 GAX24996.1 - 3.8e-08 33.7 1.1 0.072 13.4 0.2 4.0 2 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 GAX24996.1 - 6.8e-08 33.1 0.0 0.015 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAX24996.1 - 5.9e-07 29.6 0.0 0.013 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 GAX24996.1 - 7e-07 29.1 0.0 0.0027 17.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 GAX24996.1 - 7.2e-07 29.8 0.3 0.0093 16.5 0.0 3.3 4 0 0 4 4 2 2 ABC transporter RNA_helicase PF00910.22 GAX24996.1 - 2.5e-06 27.8 0.0 0.013 15.9 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Viral_helicase1 PF01443.18 GAX24996.1 - 4.2e-06 26.7 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 GAX24996.1 - 7.3e-06 25.5 0.1 0.011 15.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAX24996.1 - 7.4e-06 25.8 0.1 0.095 12.4 0.1 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 GAX24996.1 - 7.5e-06 26.0 0.9 0.41 10.5 0.0 3.9 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAX24996.1 - 9.3e-06 26.0 0.0 0.15 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 GAX24996.1 - 1e-05 25.5 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GAX24996.1 - 1.5e-05 25.0 0.4 0.53 10.2 0.0 3.5 3 1 0 3 3 3 2 NACHT domain ATPase PF06745.13 GAX24996.1 - 2.3e-05 23.8 0.2 0.059 12.7 0.1 3.1 2 1 0 2 2 2 1 KaiC CDC48_2 PF02933.17 GAX24996.1 - 2.5e-05 24.0 0.0 9e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.6 GAX24996.1 - 4.2e-05 23.2 2.2 1.2 8.7 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 GAX24996.1 - 4.7e-05 23.0 0.1 0.26 10.8 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 GAX24996.1 - 8.7e-05 22.5 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 GAX24996.1 - 0.00019 21.2 0.0 0.66 9.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain Bac_DnaA PF00308.18 GAX24996.1 - 0.00027 20.9 0.1 2.5 7.9 0.0 3.7 4 1 0 4 4 3 1 Bacterial dnaA protein Zeta_toxin PF06414.12 GAX24996.1 - 0.00028 20.3 0.1 0.66 9.2 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.6 GAX24996.1 - 0.00037 21.0 0.7 3 8.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 GAX24996.1 - 0.00039 20.8 2.9 0.098 13.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 GAX24996.1 - 0.00057 19.6 0.0 0.065 13.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain PhoH PF02562.16 GAX24996.1 - 0.0007 19.1 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Vps4_C PF09336.10 GAX24996.1 - 0.0009 19.2 0.0 0.0089 16.0 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 GAX24996.1 - 0.0012 18.0 0.1 0.045 12.8 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 GAX24996.1 - 0.0013 18.8 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 GAX24996.1 - 0.0018 17.5 0.0 0.84 8.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.6 GAX24996.1 - 0.0021 18.2 0.5 1.3 9.2 0.0 2.7 3 0 0 3 3 2 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 GAX24996.1 - 0.0028 17.4 0.1 0.43 10.3 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase NB-ARC PF00931.22 GAX24996.1 - 0.0033 16.7 0.0 0.45 9.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.11 GAX24996.1 - 0.0071 16.2 0.0 2.2 8.1 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 GAX24996.1 - 0.0084 15.9 0.0 4.3 7.1 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AP3D1 PF06375.11 GAX24996.1 - 0.0089 16.3 2.7 0.02 15.1 2.7 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 NTPase_1 PF03266.15 GAX24996.1 - 0.012 15.6 0.5 5.7 6.8 0.0 3.3 2 1 1 3 3 3 0 NTPase Molydop_binding PF01568.21 GAX24996.1 - 0.017 15.2 0.1 0.62 10.1 0.0 2.6 2 1 1 3 3 2 0 Molydopterin dinucleotide binding domain AAA_30 PF13604.6 GAX24996.1 - 0.021 14.5 0.1 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAX24996.1 - 0.029 14.2 0.2 5.9 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF1967 PF09269.11 GAX24996.1 - 0.031 14.2 0.0 6.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) SKI PF01202.22 GAX24996.1 - 0.038 14.1 1.9 4.6 7.3 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase IPT PF01745.16 GAX24996.1 - 0.041 13.3 0.3 2.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase CPT PF07931.12 GAX24996.1 - 0.044 13.6 0.0 2.2 8.1 0.0 3.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 GAX24996.1 - 0.06 12.4 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 GAX24996.1 - 0.073 13.4 1.1 21 5.4 0.0 3.0 2 1 0 3 3 2 0 AAA domain APS_kinase PF01583.20 GAX24996.1 - 0.11 12.4 0.0 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_6 PF12774.7 GAX24996.1 - 0.2 10.6 0.2 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region SR-25 PF10500.9 GAX24996.1 - 0.68 9.5 10.6 0.34 10.5 3.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DEAD PF00270.29 GAX24998.1 - 2.7e-41 141.3 2.9 4.1e-41 140.7 0.0 2.7 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX24998.1 - 3.4e-31 107.8 0.0 8.3e-30 103.4 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX24998.1 - 0.0079 16.2 0.0 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma70_ner PF04546.13 GAX24998.1 - 0.0085 16.0 10.5 0.0085 16.0 10.5 1.9 3 0 0 3 3 3 1 Sigma-70, non-essential region zf-CCHC PF00098.23 GAX24998.1 - 0.015 15.4 0.8 0.029 14.4 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle SecA_DEAD PF07517.14 GAX24998.1 - 0.045 13.0 0.3 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain ERCC3_RAD25_C PF16203.5 GAX24998.1 - 0.081 12.1 0.0 0.26 10.5 0.0 1.8 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-CCHC_4 PF14392.6 GAX24998.1 - 0.81 9.5 3.4 1.3 8.8 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Ski2_N PF17911.1 GAX24999.1 - 0.21 11.4 0.5 12 5.7 0.3 2.1 2 0 0 2 2 2 0 Ski2 N-terminal region Sulfotransfer_2 PF03567.14 GAX25001.1 - 1.6e-05 25.0 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAX25001.1 - 6e-05 22.1 0.8 0.00044 19.3 0.8 2.3 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Lipase_GDSL_2 PF13472.6 GAX25002.1 - 3.4e-05 24.3 0.1 0.00029 21.3 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 GAX25003.1 - 0.0023 18.3 0.0 0.0057 17.1 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 GAX25004.1 - 0.00088 19.7 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_C2 PF00648.21 GAX25005.1 - 1e-71 241.4 1.5 2.5e-71 240.1 1.5 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease TIP120 PF08623.10 GAX25007.1 - 2e-36 125.3 1.1 1.5e-31 109.4 0.0 5.0 4 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 GAX25007.1 - 3.4e-13 48.6 17.5 0.076 13.3 0.0 9.7 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 GAX25007.1 - 4.5e-09 36.6 10.3 0.017 15.5 0.3 7.0 5 2 1 6 6 6 1 HEAT repeats Vps35 PF03635.17 GAX25007.1 - 0.00023 19.8 5.6 0.0087 14.6 0.4 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 Cnd1 PF12717.7 GAX25007.1 - 0.00044 20.3 14.1 0.0091 16.1 0.8 6.1 5 2 1 6 6 5 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 GAX25007.1 - 0.0016 18.6 8.8 1.1 9.5 0.5 6.0 6 2 0 6 6 5 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 GAX25007.1 - 0.0032 17.9 16.5 13 6.4 0.0 8.4 9 1 1 10 10 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAX25007.1 - 0.0095 16.5 0.3 10 6.8 0.0 4.6 4 2 0 4 4 3 0 Vacuolar 14 Fab1-binding region ParcG PF10274.9 GAX25007.1 - 0.016 15.3 4.3 0.43 10.7 0.0 4.2 5 0 0 5 5 5 0 Parkin co-regulated protein SDA1 PF05285.12 GAX25007.1 - 0.031 13.7 6.6 0.096 12.1 6.9 1.6 2 0 0 2 2 2 0 SDA1 DUF5578 PF17741.1 GAX25007.1 - 0.036 13.5 6.5 2.1 7.7 0.8 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5578) Arm PF00514.23 GAX25007.1 - 0.12 12.5 2.0 34 4.7 0.1 4.7 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat Sporozoite_P67 PF05642.11 GAX25007.1 - 0.18 9.8 3.0 0.29 9.2 3.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 GAX25007.1 - 0.18 11.1 4.2 0.33 10.2 4.2 1.3 1 0 0 1 1 1 0 BUD22 EF-hand_like PF09279.11 GAX25007.1 - 0.27 11.8 2.7 7.1 7.2 0.2 3.2 2 1 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like V-ATPase_H_C PF11698.8 GAX25007.1 - 0.34 11.0 7.2 0.077 13.1 0.7 3.4 3 1 1 4 4 3 0 V-ATPase subunit H Sigma70_ner PF04546.13 GAX25007.1 - 0.57 10.0 6.7 2.1 8.2 6.7 2.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_RNA_Pol_19 PF05320.12 GAX25007.1 - 0.61 10.1 6.4 2.2 8.3 6.4 1.9 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PPP4R2 PF09184.11 GAX25007.1 - 0.77 9.3 10.0 1.7 8.1 10.0 1.5 1 0 0 1 1 1 0 PPP4R2 YL1 PF05764.13 GAX25007.1 - 2.7 8.0 9.4 5.1 7.1 9.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GAX25007.1 - 2.9 6.0 13.9 1.3 7.1 10.9 1.9 2 0 0 2 2 2 0 Nop14-like family RRN3 PF05327.11 GAX25007.1 - 4.7 5.6 8.8 1.9 6.9 4.9 2.3 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GAX25007.1 - 6 5.0 10.0 3.1 6.0 7.4 1.7 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.12 GAX25007.1 - 7.2 5.8 19.2 13 5.0 19.2 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 GAX25007.1 - 7.8 5.6 8.3 14 4.8 8.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ERCC4 PF02732.15 GAX25008.1 - 2e-20 73.6 0.0 8e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain PMSR PF01625.21 GAX25009.1 - 3.6e-56 189.6 0.7 5.1e-56 189.1 0.7 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CAF1 PF04857.20 GAX25009.1 - 0.047 12.9 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease WD40 PF00400.32 GAX25010.1 - 0.0028 18.5 5.8 0.013 16.4 0.0 4.7 5 1 0 5 5 5 1 WD domain, G-beta repeat Mito_carr PF00153.27 GAX25011.1 - 5e-19 68.0 9.1 6.6e-07 29.2 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein ERF PF04404.12 GAX25011.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 ERF superfamily RF-1 PF00472.20 GAX25012.1 - 9.4e-23 80.4 3.6 1.4e-22 79.8 3.6 1.2 1 0 0 1 1 1 1 RF-1 domain DUF2781 PF10914.8 GAX25013.1 - 2.9e-33 115.3 10.0 4e-33 114.9 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ubiquitin PF00240.23 GAX25014.1 - 2.7e-22 78.3 0.1 5.1e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-C3HC4_3 PF13920.6 GAX25014.1 - 8.9e-13 47.9 11.5 1.6e-12 47.1 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX25014.1 - 7.6e-09 35.3 11.2 1.4e-08 34.5 11.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rad60-SLD PF11976.8 GAX25014.1 - 6e-08 32.4 0.2 2e-07 30.7 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Nuc_deoxyri_tr3 PF11071.8 GAX25015.1 - 6.4e-59 198.0 0.0 8e-59 197.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase YtoQ Nuc_deoxyri_tr2 PF15891.5 GAX25015.1 - 2e-05 24.8 0.0 0.00045 20.5 0.0 2.3 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 GAX25015.1 - 0.014 15.4 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase DUF1325 PF07039.11 GAX25018.1 - 2.3e-19 69.8 1.2 3.2e-19 69.3 0.3 1.7 2 0 0 2 2 2 1 SGF29 tudor-like domain ING PF12998.7 GAX25018.1 - 4.7e-15 56.0 3.2 2.6e-14 53.6 3.2 2.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding LBR_tudor PF09465.10 GAX25018.1 - 0.01 15.6 0.1 7.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain NOG1_N PF17835.1 GAX25018.1 - 0.019 14.9 0.3 0.059 13.3 0.1 1.8 2 0 0 2 2 2 0 NOG1 N-terminal helical domain CHASE3 PF05227.13 GAX25018.1 - 0.03 14.2 0.7 0.03 14.2 0.7 2.1 2 0 0 2 2 2 0 CHASE3 domain Tudor_3 PF18115.1 GAX25018.1 - 0.13 12.1 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain TSP_1 PF00090.19 GAX25019.1 - 3e-06 27.3 32.8 0.0014 18.8 7.8 4.0 4 0 0 4 4 4 3 Thrombospondin type 1 domain Inv-AAD PF18785.1 GAX25020.1 - 4.5e-07 29.8 0.1 1.1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 GAX25020.1 - 2.4e-05 24.1 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region KASH_CCD PF14662.6 GAX25020.1 - 1.6 8.5 6.0 2.7 7.8 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF5321 PF17254.2 GAX25020.1 - 7 6.1 7.0 0.47 9.9 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5321) Arf PF00025.21 GAX25021.1 - 1.5e-45 154.8 0.0 1.8e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAX25021.1 - 2e-13 50.6 0.0 4e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX25021.1 - 3.8e-13 49.3 0.0 5.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAX25021.1 - 7.5e-09 35.7 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX25021.1 - 5.3e-08 32.6 0.1 9.8e-06 25.2 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAX25021.1 - 1.2e-07 31.3 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAX25021.1 - 7e-07 28.8 0.0 1.1e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAX25021.1 - 2.5e-06 26.9 0.3 0.00023 20.4 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit cobW PF02492.19 GAX25021.1 - 0.0066 16.1 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 GAX25021.1 - 0.016 14.7 0.6 0.48 9.9 0.6 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 GAX25021.1 - 0.075 12.3 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase preATP-grasp_3 PF18301.1 GAX25021.1 - 0.095 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain MMR_HSR1_Xtn PF16897.5 GAX25021.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATPase_2 PF01637.18 GAX25021.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 GAX25021.1 - 0.12 12.4 0.1 3.3 7.7 0.2 2.1 1 1 1 2 2 2 0 Dynamin family DUF3641 PF12345.8 GAX25022.1 - 7.6e-54 181.4 0.1 1.5e-53 180.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 GAX25022.1 - 4.9e-09 36.8 0.0 8.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAX25022.1 - 5.9e-06 26.6 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain UPF0203 PF05254.12 GAX25023.1 - 3.5e-10 40.0 5.9 4.8e-10 39.5 5.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CX9C PF16860.5 GAX25023.1 - 0.0036 17.3 1.6 0.66 10.0 0.1 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 GAX25023.1 - 0.01 16.0 0.7 0.01 16.0 0.7 2.0 2 0 0 2 2 2 0 CHCH domain BAR PF03114.18 GAX25024.1 - 0.00038 20.2 4.8 0.00052 19.7 4.5 1.4 1 1 0 1 1 1 1 BAR domain POX PF07526.11 GAX25024.1 - 0.0033 18.0 3.4 0.0033 18.0 3.4 2.1 2 0 0 2 2 2 1 Associated with HOX DUF4407 PF14362.6 GAX25024.1 - 0.16 11.3 3.0 0.31 10.3 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uds1 PF15456.6 GAX25024.1 - 0.2 11.9 6.2 0.12 12.6 3.6 1.9 2 0 0 2 2 2 0 Up-regulated During Septation Spectrin PF00435.21 GAX25024.1 - 0.46 11.0 7.4 0.24 11.9 1.6 2.8 3 0 0 3 3 3 0 Spectrin repeat FliD_N PF02465.18 GAX25024.1 - 1.1 10.0 10.8 3.4 8.4 0.9 3.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus LXG PF04740.12 GAX25024.1 - 1.8 8.2 8.6 1.9 8.1 4.5 2.5 2 1 0 2 2 2 0 LXG domain of WXG superfamily Actin PF00022.19 GAX25025.1 - 3.5e-67 226.8 0.0 4.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Actin VIT1 PF01988.19 GAX25026.1 - 0.019 14.8 1.2 0.019 14.8 1.2 1.8 2 1 0 2 2 2 0 VIT family DUF4061 PF13270.6 GAX25026.1 - 0.12 12.7 14.0 0.07 13.5 6.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) Exonuc_VII_L PF02601.15 GAX25026.1 - 0.15 11.6 13.1 0.015 14.8 6.5 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Macoilin PF09726.9 GAX25026.1 - 0.19 10.3 19.1 0.25 9.9 19.1 1.1 1 0 0 1 1 1 0 Macoilin family STI1 PF17830.1 GAX25026.1 - 0.21 11.5 4.3 2.8 7.9 0.1 2.9 3 0 0 3 3 3 0 STI1 domain TMPIT PF07851.13 GAX25026.1 - 1.9 7.7 4.6 4 6.6 4.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein 5_nucleotid PF05761.14 GAX25026.1 - 7.1 5.4 7.9 14 4.5 7.9 1.4 1 0 0 1 1 1 0 5' nucleotidase family CHDCT2 PF08074.11 GAX25026.1 - 9.9 6.3 8.8 1.3 9.2 4.3 1.9 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain UAA PF08449.11 GAX25028.1 - 1.9e-35 122.6 7.8 2.3e-35 122.3 7.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX25028.1 - 0.00066 19.9 9.5 0.00066 19.9 9.5 2.6 2 1 1 3 3 3 1 EamA-like transporter family DUF3693 PF12472.8 GAX25028.1 - 4.9 6.9 6.6 1.3 8.8 0.5 2.9 3 1 0 3 3 3 0 Phage related protein WD40 PF00400.32 GAX25029.1 - 1.4e-42 142.8 20.6 7e-09 36.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25029.1 - 3.8e-19 68.8 4.6 2e-05 24.8 0.3 6.1 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX25029.1 - 6.3e-10 39.2 0.4 0.0098 15.8 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A KH_1 PF00013.29 GAX25029.1 - 4.2e-07 29.7 2.6 7.2e-07 28.9 2.6 1.3 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 GAX25029.1 - 0.0016 18.3 0.3 0.003 17.4 0.3 1.4 1 0 0 1 1 1 1 KH domain SLS PF14611.6 GAX25029.1 - 0.028 14.2 0.2 0.054 13.3 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Coatomer_WDAD PF04053.14 GAX25029.1 - 0.096 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region SBD PF17882.1 GAX25029.1 - 0.13 12.1 1.1 2.5 8.0 0.1 3.0 2 1 1 3 3 3 0 OAA-family lectin sugar binding domain KH_2 PF07650.17 GAX25029.1 - 0.16 11.8 0.8 0.29 11.0 0.8 1.4 1 0 0 1 1 1 0 KH domain Archaeal_AmoA PF12942.7 GAX25031.1 - 0.12 12.0 6.3 0.1 12.3 0.6 2.5 2 1 0 3 3 3 0 Archaeal ammonia monooxygenase subunit A (AmoA) Lipase_GDSL_2 PF13472.6 GAX25032.1 - 1.7e-15 57.9 0.0 2.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX25032.1 - 6.5e-13 49.1 0.0 8.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 GAX25032.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 OSK domain Lipase_GDSL_2 PF13472.6 GAX25033.1 - 2e-16 60.9 0.1 2.5e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX25033.1 - 2e-11 44.3 0.0 3.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CP12 PF02672.15 GAX25033.1 - 0.18 12.5 0.1 1.3 9.9 0.0 2.0 2 0 0 2 2 2 0 CP12 domain TAXi_N PF14543.6 GAX25035.1 - 2e-16 60.7 1.6 3.4e-16 60.0 1.6 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX25035.1 - 1.9e-10 40.7 0.2 0.00025 20.6 0.0 3.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX25035.1 - 0.019 14.8 0.0 12 5.7 0.0 3.2 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Arcadin_1 PF18653.1 GAX25035.1 - 0.032 14.3 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Arcadin 1 ECH_1 PF00378.20 GAX25036.1 - 2.3e-35 122.1 0.0 2.9e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX25036.1 - 7.4e-15 55.3 0.0 1.3e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Thioredoxin_8 PF13905.6 GAX25037.1 - 9e-20 70.8 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX25037.1 - 0.0047 17.4 0.0 4.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 GAX25037.1 - 0.047 13.6 0.0 6.9 6.6 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.6 GAX25037.1 - 0.058 13.6 0.1 0.54 10.5 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like SdrD_B PF17210.3 GAX25039.1 - 5.2e-52 174.8 20.2 1.8e-15 57.1 3.0 4.2 4 0 0 4 4 4 4 SdrD B-like domain SpaA PF17802.1 GAX25039.1 - 5.3e-09 36.3 0.5 0.58 10.5 0.1 4.5 4 0 0 4 4 4 3 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 GAX25039.1 - 2.4e-05 24.5 7.6 1.3 9.4 0.5 4.5 4 0 0 4 4 4 3 Carboxypeptidase regulatory-like domain DUF1939 PF09154.10 GAX25039.1 - 0.00014 21.9 0.5 0.38 10.9 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1939) DUF4124 PF13511.6 GAX25039.1 - 6.5 7.2 8.0 46 4.5 0.2 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4124) Ank_5 PF13857.6 GAX25040.1 - 1.5e-10 41.1 0.6 0.21 11.9 0.0 5.4 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX25040.1 - 5.9e-10 39.6 0.0 0.0076 16.8 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX25040.1 - 1e-07 31.6 2.0 14 6.6 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 GAX25040.1 - 2.1e-07 31.3 0.7 0.24 12.0 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX25040.1 - 1.9e-06 28.1 1.4 2.6 8.7 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Hydrolase_4 PF12146.8 GAX25041.1 - 6.9e-11 41.9 0.0 2.3e-08 33.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX25041.1 - 8.9e-07 28.8 0.2 0.00022 21.0 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX25041.1 - 4.5e-05 24.2 0.0 0.00013 22.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX25041.1 - 0.0043 16.6 0.0 0.1 12.1 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 GAX25041.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF818 PF05677.12 GAX25041.1 - 0.069 12.1 0.5 0.12 11.3 0.1 1.5 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 GAX25041.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Haemadin PF09065.10 GAX25041.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.4 2 0 0 2 2 2 0 Haemadin FSH1 PF03959.13 GAX25041.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AAA PF00004.29 GAX25042.1 - 5.9e-41 140.0 0.0 1.7e-40 138.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX25042.1 - 2.7e-09 36.7 0.2 7.6e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 GAX25042.1 - 6.1e-06 26.5 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX25042.1 - 0.00012 22.1 0.1 0.00053 20.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX25042.1 - 0.00084 19.8 0.1 0.0062 16.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX25042.1 - 0.00091 19.5 0.1 0.0074 16.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GAX25042.1 - 0.0047 16.1 0.0 0.0084 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAX25042.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GAX25042.1 - 0.019 15.2 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX25042.1 - 0.03 14.0 0.1 0.15 11.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX25042.1 - 0.034 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX25042.1 - 0.054 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAX25042.1 - 0.07 12.5 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX25042.1 - 0.08 12.5 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAX25042.1 - 0.083 13.3 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 GAX25042.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cpn10 PF00166.21 GAX25044.1 - 2.1e-43 146.3 6.4 4.1e-22 78.0 0.5 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit DAP3 PF10236.9 GAX25045.1 - 2.3e-16 59.9 0.0 3.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 GAX25045.1 - 0.0019 18.6 0.5 0.014 15.8 0.5 2.5 2 1 0 2 2 2 1 AAA ATPase domain ParD_antitoxin PF03693.14 GAX25045.1 - 0.02 15.3 0.2 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DUF3782 PF12644.7 GAX25045.1 - 0.032 14.4 0.8 0.13 12.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) IstB_IS21 PF01695.17 GAX25045.1 - 0.04 13.7 0.5 0.094 12.4 0.1 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 GAX25045.1 - 0.056 13.2 1.3 0.082 12.6 0.3 1.8 2 0 0 2 2 2 0 AAA domain AAA_35 PF14516.6 GAX25045.1 - 0.057 12.2 0.3 0.84 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain ATPase_2 PF01637.18 GAX25045.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 GAX25045.1 - 0.078 13.3 0.0 1.2 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 GAX25045.1 - 0.14 12.7 0.0 0.55 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GAX25045.1 - 0.15 11.2 0.1 0.32 10.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 GAX25045.1 - 0.17 12.3 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TAL_FSA PF00923.19 GAX25047.1 - 3.5e-100 335.1 0.3 4e-100 334.9 0.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase 2OG-FeII_Oxy_2 PF13532.6 GAX25048.1 - 3.2e-29 102.5 0.0 4.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HAD_2 PF13419.6 GAX25049.1 - 4.3e-19 69.3 0.0 7.6e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX25049.1 - 6.3e-11 43.0 0.1 2.4e-10 41.1 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX25049.1 - 3.6e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 1 1 2 2 2 1 HAD-hyrolase-like DUF4575 PF15143.6 GAX25050.1 - 0.22 11.7 0.8 84 3.4 0.0 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4575) SelR PF01641.18 GAX25051.1 - 0.00022 21.3 0.0 0.00076 19.6 0.0 1.9 1 1 0 1 1 1 1 SelR domain Chloroa_b-bind PF00504.21 GAX25052.1 - 2.4e-11 44.4 0.0 1.3e-06 29.1 0.0 2.1 1 1 2 3 3 3 3 Chlorophyll A-B binding protein TAF1D PF15333.6 GAX25053.1 - 0.063 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D tRNA-synt_1e PF01406.19 GAX25054.1 - 5.1e-110 367.6 0.1 9.2e-110 366.7 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAX25054.1 - 2.1e-06 26.8 0.1 0.00074 18.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 GAX25054.1 - 0.1 13.1 0.0 0.42 11.1 0.0 2.1 1 0 0 1 1 1 0 DALR domain XRN_M PF17846.1 GAX25054.1 - 0.14 11.0 7.5 0.046 12.7 4.4 1.6 2 0 0 2 2 2 0 Xrn1 helical domain DUF1604 PF07713.13 GAX25055.1 - 2.7e-19 68.7 3.1 2.7e-19 68.7 3.1 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) Topoisom_I PF01028.20 GAX25056.1 - 1.4e-89 299.3 8.2 1.4e-89 299.3 8.2 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 GAX25056.1 - 5.2e-80 268.0 0.6 5.2e-80 268.0 0.6 4.4 4 1 2 6 6 6 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 GAX25056.1 - 3e-35 120.0 0.9 3e-35 120.0 0.9 2.8 2 0 0 2 2 2 1 C-terminal topoisomerase domain Sec66 PF09802.9 GAX25056.1 - 0.0053 16.4 10.5 0.13 11.9 0.1 2.7 2 0 0 2 2 2 2 Preprotein translocase subunit Sec66 HsbA PF12296.8 GAX25056.1 - 0.078 13.4 0.3 0.078 13.4 0.3 2.4 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Allexi_40kDa PF05549.11 GAX25056.1 - 0.15 11.5 4.2 0.42 10.1 4.2 1.8 1 0 0 1 1 1 0 Allexivirus 40kDa protein GLTP PF08718.11 GAX25057.1 - 1.5e-21 77.2 0.1 2.3e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) MatE PF01554.18 GAX25058.1 - 1.8e-41 141.5 20.2 8.4e-22 77.5 5.5 3.6 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 GAX25058.1 - 4.3e-10 39.8 5.3 4.3e-10 39.8 5.3 3.6 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Glyco_tranf_2_4 PF13704.6 GAX25059.1 - 3.8e-10 40.2 0.5 1.4e-09 38.4 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX25059.1 - 0.0022 17.7 1.1 0.0068 16.1 1.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 92 Methyltransf_16 PF10294.9 GAX25060.1 - 3.3e-11 43.2 0.0 7.5e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAX25060.1 - 1.8e-05 24.3 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX25060.1 - 8.8e-05 23.1 0.0 0.0027 18.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX25060.1 - 0.024 14.2 0.0 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Glyco_trans_1_4 PF13692.6 GAX25060.1 - 0.028 14.9 0.4 0.39 11.2 0.1 2.2 1 1 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX25060.1 - 0.15 11.6 1.2 0.77 9.3 0.0 2.3 3 0 0 3 3 3 0 Glycosyl transferases group 1 MCM PF00493.23 GAX25061.1 - 1.2e-96 322.1 0.0 2e-96 321.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX25061.1 - 1.2e-31 109.2 0.7 2.4e-31 108.2 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX25061.1 - 2.4e-24 85.5 2.2 5.9e-24 84.3 2.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 GAX25061.1 - 5.5e-07 29.7 0.0 3.3e-05 23.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX25061.1 - 1.7e-06 27.6 0.1 0.00017 21.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 GAX25061.1 - 3.1e-05 24.5 6.9 0.00017 22.1 6.9 2.4 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase_C PF13335.6 GAX25061.1 - 8.6e-05 23.1 0.4 8.6e-05 23.1 0.4 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 GAX25061.1 - 0.0036 17.1 0.0 0.0092 15.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 GAX25061.1 - 0.0092 15.8 0.1 0.028 14.3 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain DUF5358 PF17311.2 GAX25061.1 - 0.0092 16.0 1.8 0.019 15.0 1.8 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5358) AAA_16 PF13191.6 GAX25061.1 - 0.013 15.8 0.4 0.013 15.8 0.4 3.0 2 2 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 GAX25061.1 - 0.017 15.5 0.3 0.063 13.7 0.0 2.2 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.10 GAX25061.1 - 0.019 15.1 1.8 0.054 13.6 1.8 1.8 1 0 0 1 1 1 0 Zinc ribbon domain NTPase_1 PF03266.15 GAX25061.1 - 0.045 13.7 0.1 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 NTPase DZR PF12773.7 GAX25061.1 - 0.064 13.3 0.8 0.16 12.0 0.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 GAX25061.1 - 0.096 12.7 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 GAX25061.1 - 0.22 11.0 2.4 10 5.7 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain AAA_lid_7 PF17867.1 GAX25061.1 - 0.26 11.5 1.5 0.79 10.0 0.2 2.2 2 0 0 2 2 2 0 Midasin AAA lid domain Swi3 PF07962.12 GAX25062.1 - 1.4e-11 44.2 0.0 2.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Peptidase_M32 PF02074.15 GAX25063.1 - 1.2e-166 555.3 0.4 1.4e-166 555.1 0.4 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Methyltransf_4 PF02390.17 GAX25064.1 - 5.7e-44 149.6 0.0 7.1e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 GAX25064.1 - 7.8e-07 29.7 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX25064.1 - 0.00015 22.3 0.0 0.0003 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX25064.1 - 0.0025 17.4 0.0 0.0075 15.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX25064.1 - 0.0025 17.6 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX25064.1 - 0.0063 16.5 0.0 0.025 14.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX25064.1 - 0.007 17.1 0.0 0.015 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX25064.1 - 0.027 14.2 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 GAX25064.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family SHS2_Rpb7-N PF03876.17 GAX25064.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.5 1 1 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 R3H PF01424.22 GAX25066.1 - 1.5e-10 40.9 0.5 4.7e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 R3H domain TFIIA PF03153.13 GAX25066.1 - 7.5 6.4 34.4 0.93 9.4 5.0 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit HSP20 PF00011.21 GAX25067.1 - 8.6e-15 54.7 0.5 1.4e-14 54.1 0.5 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAX25067.1 - 0.0019 17.7 0.1 0.0041 16.7 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF111 PF01969.17 GAX25068.1 - 6.6e-64 216.3 2.8 1.2e-63 215.5 2.8 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF111 ArnB_C PF18677.1 GAX25069.1 - 0.11 12.7 0.1 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain VWA PF00092.28 GAX25070.1 - 0.044 14.0 0.1 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA_2 PF13519.6 GAX25070.1 - 0.16 12.6 0.1 17 6.1 0.0 2.5 2 0 0 2 2 2 0 von Willebrand factor type A domain PDEase_I PF00233.19 GAX25071.1 - 3e-25 89.3 0.0 4.8e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 GAX25072.1 - 3e-26 92.6 0.0 2.6e-20 73.2 0.0 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Lactamase_B_2 PF12706.7 GAX25073.1 - 0.00019 21.0 0.0 0.0006 19.4 0.0 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAX25073.1 - 0.00032 20.8 2.1 0.0006 19.9 1.6 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 GAX25073.1 - 0.045 12.9 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Lipocalin_5 PF13924.6 GAX25074.1 - 0.018 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipocalin-like domain Pyr_redox_2 PF07992.14 GAX25075.1 - 3.4e-33 115.1 0.0 4.5e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX25075.1 - 1.7e-08 34.9 0.1 4e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAX25075.1 - 0.011 14.9 0.1 2.5 7.2 0.1 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAX25075.1 - 0.016 14.0 2.0 0.77 8.4 0.0 2.4 1 1 1 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAX25075.1 - 0.019 14.2 0.0 0.057 12.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX25075.1 - 0.028 13.5 2.5 0.87 8.6 0.6 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein FMN_red PF03358.15 GAX25075.1 - 0.057 13.2 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 NADPH-dependent FMN reductase NAD_binding_9 PF13454.6 GAX25075.1 - 0.54 10.2 4.9 7.2 6.6 0.1 3.8 4 1 1 5 5 5 0 FAD-NAD(P)-binding GIDA PF01134.22 GAX25075.1 - 0.58 9.2 3.0 27 3.7 0.0 2.8 1 1 0 3 3 3 0 Glucose inhibited division protein A VDE PF07137.11 GAX25076.1 - 6.3e-25 88.1 0.0 1.1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 VDE lipocalin domain BppL_N PF18338.1 GAX25076.1 - 0.056 13.2 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain Radical_SAM PF04055.21 GAX25077.1 - 6e-08 33.2 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily CAP_GLY PF01302.25 GAX25078.1 - 1e-16 60.7 0.2 2.1e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain KASH_CCD PF14662.6 GAX25078.1 - 0.0052 16.6 26.2 0.0052 16.6 26.2 5.0 3 2 1 4 4 4 2 Coiled-coil region of CCDC155 or KASH Flt3_lig PF02947.14 GAX25078.1 - 0.14 12.3 3.2 0.58 10.4 0.1 3.4 3 1 0 3 3 3 0 flt3 ligand TUDOR PF00567.24 GAX25078.1 - 0.21 11.6 0.9 3 7.9 0.0 3.2 2 0 0 2 2 2 0 Tudor domain ABC_membrane PF00664.23 GAX25079.1 - 7.6e-49 166.8 10.8 7.6e-49 166.8 10.8 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAX25079.1 - 4.2e-33 114.8 0.0 8.3e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAX25079.1 - 5.5e-05 22.7 0.0 0.0015 18.0 0.0 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAX25079.1 - 0.00038 20.4 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAX25079.1 - 0.0006 20.1 1.3 0.0083 16.4 0.4 2.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX25079.1 - 0.0067 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 GAX25079.1 - 0.008 16.6 0.0 0.05 14.0 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX25079.1 - 0.023 15.1 0.3 0.11 12.9 0.1 2.3 2 2 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 GAX25079.1 - 0.035 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 GAX25079.1 - 0.044 14.0 0.1 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX25079.1 - 0.1 13.1 0.0 0.38 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.6 GAX25079.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 GAX25079.1 - 0.16 11.9 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain DUF3040 PF11239.8 GAX25079.1 - 0.89 9.9 2.8 1.5 9.1 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Nitroreductase PF00881.24 GAX25080.1 - 1.2e-26 93.8 0.3 3.5e-25 89.0 0.3 2.2 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 GAX25080.1 - 1.1e-06 28.4 0.0 0.04 13.5 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase F-box-like PF12937.7 GAX25081.1 - 0.00034 20.4 0.1 0.026 14.4 0.1 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 GAX25081.1 - 0.0082 16.0 0.9 0.025 14.5 0.3 2.1 2 0 0 2 2 2 1 F-box domain MDD_C PF18376.1 GAX25082.1 - 2.2e-69 233.0 0.0 3.1e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 GAX25082.1 - 1.1e-08 35.2 2.8 2.9e-08 33.8 2.8 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain UFD1 PF03152.14 GAX25083.1 - 4.1e-74 247.8 0.0 5.9e-74 247.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 VWA_2 PF13519.6 GAX25084.1 - 0.048 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain PseudoU_synth_2 PF00849.22 GAX25085.1 - 1.4e-22 80.5 0.1 8.8e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 RNA pseudouridylate synthase TRAM_LAG1_CLN8 PF03798.16 GAX25086.1 - 3.1e-12 46.7 13.6 3.8e-12 46.4 13.6 1.1 1 0 0 1 1 1 1 TLC domain Copine PF07002.16 GAX25087.1 - 1.6e-28 99.7 0.1 3.2e-28 98.7 0.1 1.5 1 1 0 1 1 1 1 Copine C2 PF00168.30 GAX25087.1 - 7.7e-16 58.3 0.0 3.8e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain GTP1_OBG PF01018.22 GAX25089.1 - 2e-52 176.9 5.1 3.2e-52 176.2 5.1 1.3 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 GAX25089.1 - 7.7e-24 84.0 0.0 1.8e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1967 PF09269.11 GAX25089.1 - 1.6e-17 63.2 0.0 5.6e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) FeoB_N PF02421.18 GAX25089.1 - 1.7e-10 40.6 0.0 3.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 GAX25089.1 - 0.00088 18.8 0.1 0.11 11.9 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAX25089.1 - 0.024 14.2 0.0 0.67 9.5 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 GAX25089.1 - 0.025 14.3 0.1 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 GAX25089.1 - 0.038 13.8 0.1 2.2 8.0 0.1 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 GAX25089.1 - 0.059 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 GAX25089.1 - 0.083 12.8 0.1 0.5 10.2 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 GAX25089.1 - 0.1 11.6 0.0 7 5.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Gtr1_RagA PF04670.12 GAX25089.1 - 0.21 10.9 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Trm112p PF03966.16 GAX25090.1 - 8.1e-10 39.1 0.0 1e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein F-box PF00646.33 GAX25091.1 - 9.4e-05 22.2 0.6 0.00025 20.8 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAX25091.1 - 0.0078 16.1 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like Ribosomal_L2_C PF03947.18 GAX25092.1 - 2.8e-42 143.9 1.4 5.3e-42 143.0 1.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAX25092.1 - 8.2e-17 60.9 0.2 2e-16 59.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DNA_primase_lrg PF04104.14 GAX25093.1 - 6.5e-65 219.2 0.1 1.1e-64 218.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF3731 PF12531.8 GAX25093.1 - 0.062 13.1 0.4 0.37 10.6 0.1 2.2 1 1 1 3 3 3 0 DNA-K related protein Fcf1 PF04900.12 GAX25094.1 - 8.1e-10 39.0 0.0 6.4e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 GAX25094.1 - 0.002 18.4 0.2 0.008 16.5 0.1 2.0 2 0 0 2 2 2 1 PIN like domain PIN_3 PF13470.6 GAX25094.1 - 0.0077 17.0 0.8 0.014 16.1 0.1 1.9 2 0 0 2 2 2 1 PIN domain DUF2203 PF09969.9 GAX25094.1 - 1.7 9.4 5.9 0.46 11.2 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) GDP_Man_Dehyd PF16363.5 GAX25095.1 - 4e-59 200.7 0.0 4.6e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX25095.1 - 4.9e-51 173.5 0.0 5.7e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX25095.1 - 8.3e-17 61.1 0.0 1.6e-16 60.1 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAX25095.1 - 5.4e-14 52.0 0.0 3.3e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAX25095.1 - 1.4e-10 41.4 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GAX25095.1 - 4.7e-09 35.8 0.0 5.3e-08 32.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 GAX25095.1 - 4.5e-06 26.0 0.0 8.6e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAX25095.1 - 1.1e-05 25.0 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GAX25095.1 - 0.00017 21.5 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX25095.1 - 0.0028 17.3 0.0 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAX25095.1 - 0.005 17.1 0.0 0.0095 16.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_C PF07479.14 GAX25096.1 - 3.2e-46 157.1 0.0 8.7e-46 155.7 0.0 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 GAX25096.1 - 1.2e-44 152.1 0.0 3e-44 150.7 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 GAX25096.1 - 0.12 13.0 0.0 5.9 7.5 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Choline_transpo PF04515.12 GAX25098.1 - 6.7e-32 111.0 28.7 1.2e-24 87.1 1.7 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter DUF4257 PF14074.6 GAX25098.1 - 0.0092 16.2 0.7 0.028 14.6 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4257) AAA PF00004.29 GAX25099.1 - 6.2e-97 321.1 0.0 3.2e-47 160.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX25099.1 - 4.6e-28 96.8 7.3 5.1e-15 55.0 0.9 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 GAX25099.1 - 8.2e-22 77.2 1.0 2.2e-21 75.8 1.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 GAX25099.1 - 2e-14 53.6 0.0 6.5e-06 26.0 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 GAX25099.1 - 2.9e-14 52.6 0.0 6.1e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 GAX25099.1 - 3e-12 47.0 0.0 7.4e-06 26.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAX25099.1 - 6.7e-12 46.1 2.1 0.00026 21.4 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 GAX25099.1 - 3e-11 43.7 0.0 2e-05 24.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 GAX25099.1 - 1.9e-10 40.9 0.1 2.7e-05 24.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX25099.1 - 2.7e-09 37.4 0.2 0.031 14.5 0.1 4.5 3 2 1 4 4 4 2 AAA domain TIP49 PF06068.13 GAX25099.1 - 5.4e-08 32.4 0.0 0.00065 19.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 GAX25099.1 - 1.4e-07 31.6 0.0 0.0067 16.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX25099.1 - 5.3e-07 30.2 0.0 0.045 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAX25099.1 - 7.4e-07 29.5 0.0 0.015 15.7 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 GAX25099.1 - 1e-06 28.3 0.3 0.059 12.8 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 GAX25099.1 - 6.4e-06 26.1 1.1 0.00042 20.3 0.2 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 GAX25099.1 - 7.8e-06 25.6 0.2 1.7 8.1 0.0 3.6 2 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 GAX25099.1 - 1e-05 25.4 0.1 0.24 11.1 0.0 3.0 2 1 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 GAX25099.1 - 1.3e-05 24.7 0.2 1.9 7.8 0.0 3.5 3 0 0 3 3 3 1 KaiC AAA_17 PF13207.6 GAX25099.1 - 1.5e-05 25.4 1.0 0.095 13.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 GAX25099.1 - 1.5e-05 24.6 0.0 0.089 12.3 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 GAX25099.1 - 2.5e-05 24.3 0.0 0.18 11.7 0.0 3.0 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea ABC_tran PF00005.27 GAX25099.1 - 2.7e-05 24.7 0.0 0.14 12.6 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 GAX25099.1 - 8e-05 22.9 0.0 0.51 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 GAX25099.1 - 8.5e-05 22.3 0.0 0.57 9.9 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 GAX25099.1 - 9e-05 22.3 0.0 0.014 15.2 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 GAX25099.1 - 0.00012 22.1 0.0 0.54 10.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAX25099.1 - 0.00013 21.7 0.0 0.18 11.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 GAX25099.1 - 0.00017 21.5 0.0 2.8 7.9 0.0 3.7 3 1 1 4 4 3 1 NACHT domain Bac_DnaA PF00308.18 GAX25099.1 - 0.0002 21.3 0.0 0.3 10.9 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein Cytidylate_kin2 PF13189.6 GAX25099.1 - 0.00022 21.4 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase-like family Parvo_NS1 PF01057.17 GAX25099.1 - 0.00023 20.4 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 GAX25099.1 - 0.00038 19.7 0.0 0.99 8.5 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activ_2 PF14532.6 GAX25099.1 - 0.00038 20.6 0.0 0.48 10.5 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAX25099.1 - 0.0004 19.7 0.0 0.68 9.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 GAX25099.1 - 0.00046 19.4 0.0 0.14 11.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 GAX25099.1 - 0.00056 20.0 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 GAX25099.1 - 0.0013 18.6 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAX25099.1 - 0.0016 18.4 0.0 0.57 10.1 0.0 3.0 3 1 0 3 3 2 1 Rad17 P-loop domain PhoH PF02562.16 GAX25099.1 - 0.0036 16.8 0.1 3.3 7.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein NTPase_1 PF03266.15 GAX25099.1 - 0.0042 17.0 0.6 4.5 7.1 0.0 3.9 3 1 1 4 4 4 0 NTPase DUF2075 PF09848.9 GAX25099.1 - 0.0054 16.0 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 GAX25099.1 - 0.008 16.5 0.3 8.6 6.7 0.1 3.2 2 1 0 3 3 2 0 AAA domain AAA_30 PF13604.6 GAX25099.1 - 0.0096 15.7 0.1 7.1 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain UFD1 PF03152.14 GAX25099.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 AAA_11 PF13086.6 GAX25099.1 - 0.011 15.5 0.2 5.1 6.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain Zot PF05707.12 GAX25099.1 - 0.033 13.8 0.0 1.1 8.9 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.22 GAX25099.1 - 0.037 14.1 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 GAX25099.1 - 0.041 13.6 0.0 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Molydop_binding PF01568.21 GAX25099.1 - 0.048 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain KAP_NTPase PF07693.14 GAX25099.1 - 0.051 12.8 0.1 2.7 7.1 0.0 3.1 2 2 1 4 4 4 0 KAP family P-loop domain TniB PF05621.11 GAX25099.1 - 0.079 12.4 0.0 17 4.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein AAA_29 PF13555.6 GAX25099.1 - 0.089 12.5 0.0 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 GAX25100.1 - 0.011 15.8 0.4 0.21 11.7 0.0 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5613 PF18467.1 GAX25100.1 - 0.019 15.3 0.5 0.097 13.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5613) ZapB PF06005.12 GAX25100.1 - 0.88 10.1 0.0 0.88 10.1 0.0 4.6 5 0 0 5 5 5 0 Cell division protein ZapB O-FucT PF10250.9 GAX25101.1 - 1.1e-45 156.8 0.0 1.5e-45 156.4 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 GAX25102.1 - 1.3e-44 153.3 0.0 1.7e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Sec1 PF00995.23 GAX25103.1 - 5e-111 372.7 0.0 6e-111 372.5 0.0 1.1 1 0 0 1 1 1 1 Sec1 family FSH1 PF03959.13 GAX25106.1 - 4.4e-16 59.2 0.0 3.5e-15 56.3 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 GAX25106.1 - 0.0013 18.5 0.0 0.0081 15.8 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX25106.1 - 0.011 16.3 0.0 0.047 14.3 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX25106.1 - 0.025 13.9 0.2 9 5.5 0.1 2.6 2 1 1 3 3 3 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 GAX25106.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Evr1_Alr PF04777.13 GAX25108.1 - 5.2e-29 100.7 2.3 5.2e-29 100.7 2.3 1.7 2 0 0 2 2 2 1 Erv1 / Alr family Adaptin_N PF01602.20 GAX25110.1 - 9.6e-110 367.6 3.2 1.1e-109 367.4 3.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAX25110.1 - 1.5e-07 31.6 4.0 0.0053 16.8 0.4 3.0 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAX25110.1 - 0.0089 16.4 9.7 1.1 9.7 0.0 5.9 5 1 1 6 6 6 1 HEAT repeats Alpha_adaptinC2 PF02883.20 GAX25110.1 - 0.0095 16.2 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_EZ PF13513.6 GAX25110.1 - 0.0096 16.4 5.8 0.27 11.8 0.0 5.6 8 0 0 8 8 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAX25110.1 - 0.06 14.0 0.8 1.1 9.9 0.0 3.1 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Exo70 PF03081.15 GAX25110.1 - 0.092 11.8 0.5 3.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Exo70 exocyst complex subunit MOR2-PAG1_N PF14222.6 GAX25110.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal RTP1_C1 PF10363.9 GAX25110.1 - 0.12 12.6 1.6 3.4 7.9 0.0 3.7 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 GAX25110.1 - 0.16 12.3 6.8 3.2 8.3 0.0 5.1 6 0 0 6 6 5 0 HEAT repeat Nucleoporin_FG PF13634.6 GAX25110.1 - 0.18 12.6 0.9 0.83 10.5 0.4 2.3 2 1 0 2 2 2 0 Nucleoporin FG repeat region GFO_IDH_MocA PF01408.22 GAX25111.1 - 2.8e-11 44.3 2.3 8e-11 42.8 2.3 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sec23_trunk PF04811.15 GAX25112.1 - 7.3e-72 241.8 0.0 1.1e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX25112.1 - 2.9e-23 81.6 0.0 5e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAX25112.1 - 4.6e-19 69.0 0.1 7.7e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAX25112.1 - 6.1e-15 55.0 6.3 1.4e-14 53.8 6.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAX25112.1 - 1.5e-07 31.2 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Endothelin PF00322.17 GAX25112.1 - 0.53 9.9 2.4 1.2 8.8 2.4 1.6 1 0 0 1 1 1 0 Endothelin family MRNIP PF15749.5 GAX25112.1 - 1.1 10.0 2.3 1.9 9.3 2.3 1.3 1 0 0 1 1 1 0 MRN-interacting protein Dynamin_M PF01031.20 GAX25113.1 - 3.3e-22 79.0 0.3 1.5e-14 53.9 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 GAX25113.1 - 3.7e-17 62.9 0.0 8.5e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAX25113.1 - 3.1e-05 24.0 0.1 0.00013 22.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAX25113.1 - 0.0074 16.8 0.1 0.028 15.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter F_actin_bind PF08919.10 GAX25113.1 - 0.032 14.3 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 F-actin binding ANAPC4_WD40 PF12894.7 GAX25114.1 - 4e-05 23.8 0.1 0.006 16.9 0.0 3.2 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 GAX25114.1 - 0.001 19.0 0.1 0.0026 17.7 0.1 1.8 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Nbas_N PF15492.6 GAX25114.1 - 0.0047 16.3 0.1 0.63 9.3 0.0 2.2 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 GAX25114.1 - 0.021 15.7 0.2 0.69 10.9 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 GAX25114.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus HMA PF00403.26 GAX25117.1 - 2.9e-13 50.0 0.2 3.2e-13 49.9 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 GAX25117.1 - 0.031 14.6 0.2 0.046 14.1 0.2 1.3 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain MFS_1 PF07690.16 GAX25118.1 - 5.7e-21 74.8 20.7 8.6e-21 74.2 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX25118.1 - 1.2e-18 67.2 25.9 4.9e-14 52.0 4.6 2.4 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 GAX25118.1 - 1.5e-05 24.4 2.9 1.5e-05 24.4 2.9 2.5 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB ANAPC4_WD40 PF12894.7 GAX25119.1 - 7.9e-08 32.5 3.4 0.038 14.3 0.2 4.5 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX25119.1 - 6.6e-07 29.9 7.2 0.55 11.2 0.0 5.4 3 1 1 4 4 4 3 WD domain, G-beta repeat Nbas_N PF15492.6 GAX25119.1 - 9.7e-05 21.8 0.1 0.014 14.7 0.0 2.2 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal POTRA_2 PF08479.11 GAX25120.1 - 0.0066 16.3 0.1 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 POTRA domain, ShlB-type Bac_surface_Ag PF01103.23 GAX25120.1 - 0.067 12.7 0.0 0.57 9.6 0.0 2.2 2 0 0 2 2 2 0 Surface antigen Polysacc_deac_1 PF01522.21 GAX25120.1 - 0.14 12.0 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide deacetylase GST_C_2 PF13410.6 GAX25121.1 - 2.8e-09 36.8 0.2 7.1e-09 35.6 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX25121.1 - 1.8e-05 24.9 0.0 3.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX25121.1 - 8.2e-05 22.9 0.0 0.00029 21.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAX25121.1 - 0.00011 22.4 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAX25121.1 - 0.00012 22.6 0.0 0.00027 21.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAX25121.1 - 0.0019 18.9 0.0 0.0044 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 GAX25121.1 - 0.046 14.0 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF5620 PF18522.1 GAX25121.1 - 0.069 13.5 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) Phycobilisome PF00502.19 GAX25121.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome protein WD40 PF00400.32 GAX25122.1 - 8.4e-14 51.8 9.6 0.006 17.4 0.4 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25122.1 - 1e-13 51.4 2.5 0.011 16.0 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 GAX25122.1 - 0.00015 21.2 0.1 0.018 14.4 0.0 2.6 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.7 GAX25122.1 - 0.0019 18.1 0.2 0.011 15.6 0.1 2.5 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Rhomboid PF01694.22 GAX25124.1 - 1.3e-18 67.5 4.9 2.1e-18 66.8 4.9 1.3 1 0 0 1 1 1 1 Rhomboid family Med22 PF06179.12 GAX25125.1 - 3.5e-07 30.4 0.1 5e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Fasciclin PF02469.22 GAX25128.1 - 7.3e-38 129.7 0.3 2.9e-22 79.2 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain Chorismate_bind PF00425.18 GAX25132.1 - 9.8e-53 179.3 0.0 1.7e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme TPP_enzyme_N PF02776.18 GAX25132.1 - 1.3e-33 116.1 1.0 3.1e-33 114.8 0.7 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Abhydrolase_1 PF00561.20 GAX25132.1 - 5.2e-09 36.1 0.1 1.3e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold MR_MLE_C PF13378.6 GAX25132.1 - 5.9e-09 35.8 0.5 8.9e-08 32.0 0.1 2.6 2 0 0 2 2 2 1 Enolase C-terminal domain-like Polyketide_cyc2 PF10604.9 GAX25132.1 - 1.6e-05 25.2 0.2 3.9e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX25132.1 - 0.0012 19.0 0.2 0.0061 16.8 0.2 2.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TPP_enzyme_M PF00205.22 GAX25132.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAX25132.1 - 0.017 14.9 0.1 0.22 11.3 0.1 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_hydro_99 PF16317.5 GAX25132.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 SAM_1 PF00536.30 GAX25134.1 - 0.006 17.0 0.0 0.019 15.4 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAX25134.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 GAX25134.1 - 0.035 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Mito_carr PF00153.27 GAX25135.1 - 5.6e-46 154.4 5.6 4.2e-17 61.9 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein PGAP1 PF07819.13 GAX25136.1 - 2e-37 129.1 0.1 3e-37 128.6 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAX25136.1 - 1.9e-05 25.4 0.8 3.7e-05 24.4 0.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX25136.1 - 0.00012 21.9 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX25136.1 - 0.0009 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 GAX25136.1 - 0.001 18.7 1.3 0.004 16.7 0.1 2.3 3 0 0 3 3 3 1 Lipid-droplet associated hydrolase Esterase PF00756.20 GAX25136.1 - 0.0067 16.1 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase DUF676 PF05057.14 GAX25136.1 - 0.011 15.2 0.1 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GAX25136.1 - 0.029 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 GAX25136.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 GAX25136.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 GAX25136.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_8 PF06259.12 GAX25136.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Glyco_hydro_36 PF17167.4 GAX25136.1 - 0.22 10.1 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF4231 PF14015.6 GAX25136.1 - 0.31 11.5 1.4 3.2 8.3 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF485 PF04341.12 GAX25136.1 - 5.1 7.1 12.6 1.3 9.0 3.4 3.4 3 1 0 3 3 2 0 Protein of unknown function, DUF485 DUF2806 PF10987.8 GAX25139.1 - 0.088 12.7 0.2 0.26 11.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2806) PEMT PF04191.13 GAX25140.1 - 6.8e-13 48.9 0.0 1.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 GAX25140.1 - 1.1e-05 25.8 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NnrU PF07298.11 GAX25140.1 - 0.00059 19.4 0.2 0.0011 18.5 0.2 1.5 1 1 0 1 1 1 1 NnrU protein DUF3098 PF11297.8 GAX25140.1 - 0.52 9.9 4.3 9 6.0 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3098) SNF2_N PF00176.23 GAX25141.1 - 1.2e-69 234.7 0.3 2.1e-69 233.9 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 GAX25141.1 - 0.00015 22.0 3.2 0.00015 22.0 3.2 4.5 3 1 0 3 3 3 1 Ring finger domain Helicase_C PF00271.31 GAX25141.1 - 0.00016 22.0 0.0 0.00042 20.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_11 PF17123.5 GAX25141.1 - 0.033 13.9 1.3 0.2 11.4 1.3 2.5 1 0 0 1 1 1 0 RING-like zinc finger XRN_N PF03159.18 GAX25141.1 - 0.11 11.9 0.6 0.24 10.8 0.6 1.5 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus zf-RING_UBOX PF13445.6 GAX25141.1 - 8 6.6 10.3 0.53 10.3 1.4 3.6 4 0 0 4 4 4 0 RING-type zinc-finger MFS_5 PF05631.14 GAX25142.1 - 6.3e-88 295.0 10.9 9.9e-88 294.4 10.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAX25142.1 - 2.2e-20 72.9 50.5 8.1e-18 64.5 31.8 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.13 GAX25142.1 - 0.025 13.0 5.5 0.024 13.0 0.3 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector SIMPL PF04402.14 GAX25143.1 - 0.085 13.3 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) ANAPC4_WD40 PF12894.7 GAX25144.1 - 1.4e-15 57.3 4.3 0.00098 19.4 0.1 5.6 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX25144.1 - 8.4e-15 54.9 12.8 1.1e-05 26.0 0.5 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAX25144.1 - 0.0024 16.9 0.1 2.6 6.9 0.0 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAX25144.1 - 0.0025 17.2 3.8 0.32 10.3 0.1 3.8 2 2 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.7 GAX25144.1 - 0.0055 16.7 0.5 0.017 15.1 0.1 2.3 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term RAB3GAP2_N PF14655.6 GAX25144.1 - 0.015 14.6 0.0 0.081 12.2 0.0 2.0 2 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Vps16_N PF04841.13 GAX25144.1 - 0.071 11.8 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region IKI3 PF04762.12 GAX25144.1 - 0.087 10.8 0.1 0.77 7.7 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Acyltransferase PF01553.21 GAX25145.1 - 3.6e-11 42.8 0.0 5.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase RVT_2 PF07727.14 GAX25146.1 - 5e-18 65.6 0.1 3.6e-17 62.8 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAD_binding_1 PF00175.21 GAX25147.1 - 7.8e-30 103.7 0.0 1.1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX25147.1 - 1.7e-28 98.9 0.0 2.7e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAX25147.1 - 5.1e-05 23.5 0.0 0.0056 16.8 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain YscW PF09619.10 GAX25147.1 - 0.14 12.5 0.3 6.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Type III secretion system lipoprotein chaperone (YscW) CDC27 PF09507.10 GAX25148.1 - 0.031 13.7 14.4 0.051 13.0 14.4 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.10 GAX25148.1 - 0.25 11.7 10.4 0.41 10.9 10.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Macoilin PF09726.9 GAX25148.1 - 0.31 9.5 5.9 0.41 9.2 5.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF3827 PF12877.7 GAX25148.1 - 0.56 8.5 9.4 0.86 7.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SR-25 PF10500.9 GAX25148.1 - 0.71 9.4 24.3 1.6 8.3 24.3 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 GAX25148.1 - 2.5 7.8 15.6 4.2 7.0 15.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4674 PF15719.5 GAX25148.1 - 2.5 8.1 22.1 4.9 7.1 22.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Med19 PF10278.9 GAX25148.1 - 8.4 6.3 18.9 14 5.6 18.9 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Zn_clus PF00172.18 GAX25149.1 - 1.5e-06 28.3 11.0 1.5e-06 28.3 11.0 2.5 3 1 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 GAX25150.1 - 1.1e-15 57.8 19.4 0.00016 22.4 0.8 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25150.1 - 4.3e-15 55.8 5.5 0.0014 18.9 0.0 5.5 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 GAX25150.1 - 0.00024 21.1 0.7 0.0014 18.6 0.4 2.3 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Nbas_N PF15492.6 GAX25150.1 - 0.00087 18.7 0.1 0.0086 15.4 0.0 2.2 1 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Meth_synt_2 PF01717.18 GAX25151.1 - 3.5e-141 470.1 0.0 7.7e-140 465.7 0.0 2.3 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAX25151.1 - 1.1e-77 261.6 0.0 2.8e-72 243.9 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Myc_N PF01056.18 GAX25152.1 - 0.13 12.1 8.8 5.3 6.9 5.3 2.2 2 0 0 2 2 2 0 Myc amino-terminal region NOA36 PF06524.12 GAX25152.1 - 0.2 10.9 23.0 0.33 10.2 15.0 2.2 2 0 0 2 2 2 0 NOA36 protein DTHCT PF08070.11 GAX25152.1 - 1.9 9.3 15.6 6 7.7 9.9 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF4611 PF15387.6 GAX25152.1 - 2.1 8.6 23.0 2.6 8.3 14.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 GAX25152.1 - 3.7 7.5 17.1 2.2 8.3 9.9 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 GAX25152.1 - 3.9 7.9 29.3 2.5 8.5 0.8 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.11 GAX25152.1 - 5 5.1 18.9 0.27 9.3 11.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TFIIF_alpha PF05793.12 GAX25152.1 - 9.7 4.6 24.9 0.44 9.1 16.3 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 GAX25153.1 - 7.2e-07 28.8 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 GAX25153.1 - 1.8e-06 27.7 0.0 0.45 10.9 0.2 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 GAX25153.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAX25153.1 - 0.18 12.2 0.0 1.2 9.5 0.0 2.3 1 1 1 2 2 2 0 HEAT repeats zf-RING_2 PF13639.6 GAX25154.1 - 1e-11 45.0 10.7 2.2e-11 43.9 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX25154.1 - 1.3e-10 40.8 4.1 3.1e-10 39.6 4.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX25154.1 - 5.3e-09 35.8 7.2 1.2e-08 34.7 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX25154.1 - 2e-08 33.9 10.7 4.7e-08 32.7 10.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX25154.1 - 3.5e-08 33.6 8.2 9.7e-08 32.2 8.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX25154.1 - 7.2e-05 22.7 6.8 0.00017 21.6 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX25154.1 - 0.00038 20.3 10.1 0.00073 19.5 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX25154.1 - 0.0011 18.8 9.1 0.0021 17.9 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX25154.1 - 0.0023 18.0 5.1 0.0074 16.3 5.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2140 PF09911.9 GAX25154.1 - 0.0031 17.1 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2140) Zn_ribbon_17 PF17120.5 GAX25154.1 - 0.0038 16.8 6.5 0.0098 15.5 6.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX25154.1 - 0.0055 16.5 5.9 0.012 15.5 5.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-HC5HC2H_2 PF13832.6 GAX25154.1 - 0.0093 16.1 2.6 0.025 14.7 2.6 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain LST1 PF05083.13 GAX25154.1 - 0.021 15.1 0.2 0.047 14.0 0.2 1.6 1 0 0 1 1 1 0 LST-1 protein UPF0228 PF05727.11 GAX25154.1 - 0.023 14.5 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0228) Tweety PF04906.13 GAX25154.1 - 0.04 12.6 0.2 0.092 11.4 0.2 1.5 1 1 1 2 2 2 0 Tweety PHD PF00628.29 GAX25154.1 - 0.081 12.8 9.8 0.18 11.7 9.8 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 GAX25154.1 - 0.28 11.3 5.8 0.65 10.2 5.8 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 GAX25154.1 - 0.33 11.2 5.1 1.1 9.5 5.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 GAX25154.1 - 0.71 9.7 9.4 2.7 7.9 9.4 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 GAX25154.1 - 1.1 9.4 11.4 0.18 11.9 7.2 1.9 2 0 0 2 2 1 0 RING-variant domain zf-RING-like PF08746.11 GAX25154.1 - 1.4 9.3 6.9 2.7 8.4 6.9 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 GAX25154.1 - 2.5 8.0 7.8 4.7 7.1 7.8 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon tRNA-synt_2c PF01411.19 GAX25155.1 - 1.1e-206 687.6 0.0 1.4e-206 687.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAX25155.1 - 1.6e-16 60.1 0.0 3.3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAX25155.1 - 1.4e-10 41.7 6.3 1.4e-10 41.7 6.3 1.8 2 0 0 2 2 2 1 DHHA1 domain Peptidase_M24 PF00557.24 GAX25156.1 - 1.5e-15 57.5 0.1 7.9e-10 38.8 0.1 2.2 2 0 0 2 2 2 2 Metallopeptidase family M24 ThrE PF06738.12 GAX25156.1 - 0.13 11.6 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter PCO_ADO PF07847.12 GAX25157.1 - 6.5e-36 123.7 0.0 1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO DUF4268 PF14088.6 GAX25158.1 - 0.12 12.3 0.7 0.3 10.9 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4268) Proteasome PF00227.26 GAX25159.1 - 1.7e-40 138.5 0.0 2.4e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX25159.1 - 1.1e-12 47.4 0.1 1.1e-12 47.4 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MA3 PF02847.17 GAX25160.1 - 4.5e-35 120.1 0.5 8e-21 74.1 0.1 2.3 2 0 0 2 2 2 2 MA3 domain Memo PF01875.17 GAX25161.1 - 7.6e-73 245.0 0.0 8.8e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MtrG PF04210.13 GAX25162.1 - 0.081 12.8 3.6 0.73 9.7 0.3 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G UVR PF02151.19 GAX25162.1 - 3.2 7.6 36.2 0.13 12.1 3.0 5.7 5 0 0 5 5 5 0 UvrB/uvrC motif PT PF04886.12 GAX25163.1 - 2.8e-45 151.5 437.1 1.2e-05 24.8 21.6 26.5 9 8 12 21 21 21 17 PT repeat YHYH PF14240.6 GAX25164.1 - 8.1e-19 68.3 0.0 8.6e-10 38.9 0.0 3.4 1 1 1 2 2 2 2 YHYH protein 2-Hacid_dh_C PF02826.19 GAX25165.1 - 7.5e-41 139.4 0.0 1.5e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 GAX25165.1 - 5.8e-19 68.5 0.0 1.9e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX25165.1 - 1.1e-16 61.3 0.1 4.9e-15 56.0 0.1 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX25165.1 - 8.7e-13 48.3 0.1 1.6e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX25165.1 - 1.4e-08 34.3 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAX25165.1 - 1e-07 31.9 0.1 2.6e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh PF00389.30 GAX25165.1 - 7.6e-07 28.9 0.0 2.1e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Methyltransf_24 PF13578.6 GAX25165.1 - 4.9e-05 24.3 0.0 0.00015 22.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_2 PF03446.15 GAX25165.1 - 0.00015 22.0 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CMAS PF02353.20 GAX25165.1 - 0.00044 19.6 0.1 0.00064 19.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 GAX25165.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_3 PF01596.17 GAX25165.1 - 0.0082 15.3 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_16 PF10294.9 GAX25165.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 GAX25165.1 - 0.023 15.4 0.0 0.067 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain GFO_IDH_MocA PF01408.22 GAX25165.1 - 0.035 14.9 0.0 0.1 13.4 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 GAX25165.1 - 0.052 14.1 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 GAX25166.1 - 1.5e-36 126.4 0.0 2.3e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAX25166.1 - 2e-20 72.0 1.1 2.8e-13 48.4 0.0 3.8 4 0 0 4 4 4 3 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 GAX25166.1 - 0.017 15.0 0.0 0.071 13.0 0.0 2.0 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TSP_3 PF02412.18 GAX25167.1 - 0.0004 20.0 399.5 0.0039 16.8 5.8 25.3 25 1 0 25 25 25 23 Thrombospondin type 3 repeat HMG_CoA_synt_C PF08540.10 GAX25169.1 - 8.4e-66 222.4 1.4 1.2e-65 221.9 1.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 GAX25169.1 - 5.7e-63 211.9 0.9 1.1e-62 210.9 0.1 1.9 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 GAX25169.1 - 4.8e-10 39.5 5.4 8.3e-08 32.1 5.9 3.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAX25169.1 - 7.3e-07 29.0 6.8 1.6e-05 24.6 0.1 4.3 4 0 0 4 4 4 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 GAX25169.1 - 0.00086 19.4 0.1 0.0037 17.4 0.1 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ald_Xan_dh_C2 PF02738.18 GAX25170.1 - 1.2e-175 585.2 0.1 1.8e-175 584.6 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 GAX25170.1 - 6e-38 130.2 0.0 1.2e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 GAX25170.1 - 7.9e-29 99.5 0.0 2.3e-28 98.0 0.0 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 GAX25170.1 - 6e-28 97.0 0.2 1.7e-27 95.6 0.2 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 GAX25170.1 - 8.1e-16 58.3 0.0 1.6e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 GAX25170.1 - 3.6e-05 23.6 0.1 3.6e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain adh_short PF00106.25 GAX25171.1 - 4.9e-35 120.8 0.0 6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX25171.1 - 3e-22 79.3 0.0 4.1e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX25171.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX25171.1 - 1.1e-05 24.8 0.1 1.5e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 GAX25171.1 - 0.00029 20.3 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Pyr_redox_2 PF07992.14 GAX25171.1 - 0.011 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CbiA PF01656.23 GAX25171.1 - 0.036 14.1 0.0 0.069 13.2 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 3HCDH_N PF02737.18 GAX25171.1 - 0.044 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAX25171.1 - 0.087 12.3 0.2 0.12 11.9 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.6 GAX25171.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Periplasmic binding protein zf-MYND PF01753.18 GAX25173.1 - 6.5e-05 22.9 10.4 0.00012 22.1 10.4 1.4 1 0 0 1 1 1 1 MYND finger DUF3244 PF11589.8 GAX25173.1 - 0.00012 22.1 0.0 0.047 13.8 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3244) BiPBP_C PF06832.12 GAX25173.1 - 0.002 18.1 6.8 45 4.2 0.0 8.3 10 1 0 10 10 10 0 Penicillin-Binding Protein C-terminus Family DUF824 PF05688.11 GAX25173.1 - 0.019 14.8 1.5 16 5.4 0.2 4.8 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) PSII_BNR PF14870.6 GAX25173.1 - 0.024 13.9 0.1 5.9 6.0 0.0 3.9 2 1 2 4 4 4 0 Photosynthesis system II assembly factor YCF48 PPC PF04151.15 GAX25173.1 - 0.024 15.7 4.8 3.8 8.7 0.1 5.4 5 1 0 5 5 5 0 Bacterial pre-peptidase C-terminal domain FlgD_ig PF13860.6 GAX25173.1 - 0.27 11.1 4.0 5.3 7.0 0.2 5.1 5 1 0 5 5 5 0 FlgD Ig-like domain zf-Mss51 PF13824.6 GAX25173.1 - 2 8.6 7.0 5.4 7.2 7.0 1.7 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 QRPTase_C PF01729.19 GAX25174.1 - 1.9e-54 184.0 0.3 2.4e-54 183.6 0.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 GAX25174.1 - 1.1e-14 54.2 0.0 3.1e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain LysR_substrate PF03466.20 GAX25174.1 - 0.068 12.5 0.5 0.2 11.0 0.1 2.0 2 1 1 3 3 3 0 LysR substrate binding domain UPF0203 PF05254.12 GAX25175.1 - 0.0026 17.9 1.7 0.22 11.8 0.3 2.5 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) CX9C PF16860.5 GAX25175.1 - 0.012 15.6 1.2 0.012 15.6 1.2 2.2 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GCK PF07802.11 GAX25175.1 - 0.35 11.3 4.9 0.65 10.5 0.3 2.4 1 1 1 2 2 2 0 GCK domain Cmc1 PF08583.10 GAX25175.1 - 0.55 10.3 8.6 0.27 11.3 2.2 3.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Voltage_CLC PF00654.20 GAX25176.1 - 1.3e-26 93.7 33.5 2.4e-20 73.1 8.6 3.3 2 1 0 3 3 3 3 Voltage gated chloride channel Sulfotransfer_3 PF13469.6 GAX25177.1 - 5.3e-06 27.0 1.7 0.00017 22.0 0.3 3.1 2 1 0 2 2 2 1 Sulfotransferase family CBM_6 PF03422.15 GAX25178.1 - 2.4e-22 79.6 1.2 7.7e-11 42.4 0.1 2.2 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX25178.1 - 2.6e-08 34.0 0.3 0.00026 21.1 0.0 2.3 2 0 0 2 2 2 2 DUF5010 C-terminal domain PT PF04886.12 GAX25179.1 - 8e-05 22.1 20.8 8e-05 22.1 20.8 2.6 2 1 0 2 2 2 1 PT repeat FAP PF07174.11 GAX25179.1 - 1.1 8.7 12.0 1.5 8.2 12.0 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Cellulase PF00150.18 GAX25180.1 - 2.1e-20 73.3 3.8 3.9e-20 72.4 3.8 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_6 PF03422.15 GAX25180.1 - 4.4e-13 49.6 0.2 2.6e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX25180.1 - 1.2e-05 25.4 0.4 0.14 12.3 0.0 3.0 3 0 0 3 3 3 2 DUF5010 C-terminal domain DUF4384 PF14326.6 GAX25180.1 - 0.037 14.1 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) CBM_6 PF03422.15 GAX25181.1 - 1.6e-30 105.9 1.7 4.8e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX25181.1 - 3.7e-15 56.1 6.1 1.1e-14 54.5 6.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX25181.1 - 5.2e-07 29.8 0.5 0.00026 21.1 0.2 2.7 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX25181.1 - 5.8e-05 23.3 0.3 0.39 11.0 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) DUF3385 PF11865.8 GAX25181.1 - 0.0011 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) PT PF04886.12 GAX25181.1 - 1.4 8.5 9.7 3.1 7.4 9.4 1.7 1 1 0 1 1 1 0 PT repeat CBM_6 PF03422.15 GAX25182.1 - 4.5e-36 123.9 1.4 5e-19 68.8 0.5 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX25182.1 - 1e-11 44.9 0.1 6.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX25182.1 - 1.3e-06 28.7 0.5 0.0032 17.7 0.2 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) OB_NTP_bind PF07717.16 GAX25183.1 - 6e-15 55.4 0.0 1.6e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX25183.1 - 1.9e-14 53.9 0.0 5.3e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 GAX25183.1 - 1.4e-12 47.8 1.5 5.7e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 GAX25183.1 - 1.5e-06 28.1 0.1 9.1e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DND1_DSRM PF14709.7 GAX25183.1 - 0.00019 21.6 0.1 0.00066 19.9 0.1 2.0 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 GAX25183.1 - 0.0019 18.5 0.0 0.0085 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX25183.1 - 0.0024 17.0 0.0 0.0051 15.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 GAX25183.1 - 0.0037 17.7 0.1 0.02 15.3 0.1 2.3 1 0 0 1 1 1 1 AAA ATPase domain RWD PF05773.22 GAX25183.1 - 0.0037 17.5 0.0 0.015 15.6 0.0 2.1 1 1 0 1 1 1 1 RWD domain AAA_7 PF12775.7 GAX25183.1 - 0.011 15.3 0.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 GAX25183.1 - 0.017 15.4 0.7 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GAX25183.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 GAX25183.1 - 0.047 14.2 0.4 4 7.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAX25183.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 GAX25183.1 - 0.065 13.1 0.0 0.33 10.9 0.0 2.1 3 0 0 3 3 3 0 Rad17 P-loop domain ABC_tran PF00005.27 GAX25183.1 - 0.065 13.7 0.3 0.25 11.8 0.0 2.2 2 0 0 2 2 1 0 ABC transporter APC1_C PF18122.1 GAX25183.1 - 0.14 12.1 0.6 0.46 10.4 0.1 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF4460 PF14687.6 GAX25183.1 - 6 7.0 5.8 8.3 6.5 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4460) HSF_DNA-bind PF00447.17 GAX25184.1 - 2.3e-18 66.6 0.1 6.3e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding DUF5065 PF16723.5 GAX25185.1 - 0.1 12.7 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) Tn7_Tnp_TnsA_C PF08721.11 GAX25185.1 - 0.12 13.0 1.4 0.27 11.9 1.0 1.8 1 1 1 2 2 2 0 TnsA endonuclease C terminal FapA PF03961.13 GAX25185.1 - 0.19 10.3 1.2 0.21 10.1 1.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ELFV_dehydrog PF00208.21 GAX25186.1 - 1.3e-37 129.8 0.0 2.1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAX25186.1 - 8.9e-19 66.6 1.8 9.8e-13 46.6 0.0 3.8 4 0 0 4 4 4 3 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 GAX25186.1 - 0.015 15.2 0.0 0.071 13.0 0.0 2.1 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TSP_3 PF02412.18 GAX25187.1 - 0.0017 18.0 401.1 0.003 17.2 5.4 25.3 25 1 0 25 25 25 21 Thrombospondin type 3 repeat Inhibitor_I53 PF11714.8 GAX25188.1 - 0.096 12.9 0.1 0.096 12.9 0.1 2.0 2 0 0 2 2 2 0 Thrombin inhibitor Madanin DUF285 PF03382.14 GAX25190.1 - 1.1e-120 396.5 56.5 2e-33 114.7 8.3 3.0 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 LEF-4 PF05098.12 GAX25190.1 - 0.0011 17.9 0.1 0.002 17.0 0.1 1.4 1 0 0 1 1 1 1 Late expression factor 4 (LEF-4) Terpene_synth_C PF03936.16 GAX25190.1 - 0.077 12.3 0.2 18 4.6 0.0 3.5 3 2 0 3 3 3 0 Terpene synthase family, metal binding domain U5_2-snRNA_bdg PF10597.9 GAX25190.1 - 1.6 8.8 4.7 9.4 6.3 0.1 3.3 1 1 3 4 4 4 0 U5-snRNA binding site 2 of PrP8 DDE_Tnp_4 PF13359.6 GAX25191.1 - 2.8e-29 101.8 0.0 2.8e-28 98.6 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease RVT_2 PF07727.14 GAX25191.1 - 1.9e-09 37.5 0.2 3.4e-08 33.4 0.2 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1 PF01609.21 GAX25191.1 - 2.5e-08 33.8 2.0 1.9e-07 30.9 0.2 3.1 2 1 0 2 2 2 1 Transposase DDE domain Plant_tran PF04827.14 GAX25191.1 - 6.9e-05 22.5 0.0 0.0003 20.5 0.0 2.1 2 0 0 2 2 2 1 Plant transposon protein Cas_Cas2CT1978 PF09707.10 GAX25191.1 - 0.13 12.3 0.1 0.49 10.5 0.1 2.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) ING PF12998.7 GAX25192.1 - 0.085 13.5 2.8 0.74 10.4 0.0 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding FUSC PF04632.12 GAX25192.1 - 0.36 9.3 0.3 0.91 8.0 0.0 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Enkurin PF13864.6 GAX25192.1 - 3.1 8.3 8.9 0.55 10.7 4.1 2.2 2 1 0 2 2 2 0 Calmodulin-binding YHYH PF14240.6 GAX25193.1 - 3e-18 66.5 0.0 1.7e-09 38.0 0.0 3.3 1 1 1 2 2 2 2 YHYH protein DUF1800 PF08811.11 GAX25194.1 - 3.1e-41 141.8 0.0 4.4e-23 82.0 0.0 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX25194.1 - 7.3e-31 107.6 4.3 1.3e-30 106.8 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX25194.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF2639 PF11121.8 GAX25194.1 - 0.34 11.0 1.0 0.78 9.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) Methyltransf_21 PF05050.12 GAX25195.1 - 0.00013 22.0 0.1 0.00028 21.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF1611_N PF17396.2 GAX25195.1 - 0.064 13.5 0.0 0.86 9.9 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain GCK PF07802.11 GAX25195.1 - 0.71 10.3 3.3 0.45 11.0 0.5 2.1 2 0 0 2 2 2 0 GCK domain PEPcase PF00311.17 GAX25196.1 - 1e-245 817.7 0.0 2e-245 816.6 0.0 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GAX25196.1 - 0.00088 17.9 0.0 0.0014 17.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Hydrolase_6 PF13344.6 GAX25197.1 - 2.9e-21 75.5 0.0 6.8e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX25197.1 - 1.7e-13 50.4 0.0 1.3e-12 47.6 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 GAX25197.1 - 7.2e-13 49.0 0.0 1.4e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX25197.1 - 3.1e-12 47.2 0.0 6.3e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAX25197.1 - 0.00015 21.5 0.0 0.037 13.7 0.0 2.5 3 0 0 3 3 3 2 Mitochondrial PGP phosphatase HAD PF12710.7 GAX25197.1 - 0.076 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA PF00004.29 GAX25199.1 - 1.3e-42 145.4 0.0 2.4e-39 134.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAX25199.1 - 9.1e-06 25.6 0.1 2.4e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 GAX25199.1 - 0.00018 21.9 0.1 0.0067 16.8 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 GAX25199.1 - 0.0002 21.9 0.0 0.0007 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAX25199.1 - 0.0011 18.8 0.0 0.0034 17.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX25199.1 - 0.0033 17.7 1.8 0.015 15.5 0.1 3.0 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 GAX25199.1 - 0.0073 16.3 0.1 0.037 14.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAX25199.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 GAX25199.1 - 0.031 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAX25199.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 GAX25199.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAX25199.1 - 0.084 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAX25199.1 - 0.095 12.4 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 GAX25199.1 - 0.096 13.1 0.0 0.46 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX25199.1 - 0.097 12.4 0.1 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX25199.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase DUF815 PF05673.13 GAX25199.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Cu-oxidase_2 PF07731.14 GAX25200.1 - 2.2e-24 85.7 1.0 2.2e-24 85.7 1.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAX25200.1 - 1.5e-14 54.1 1.3 8.3e-09 35.5 0.3 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 GAX25200.1 - 0.00014 22.0 0.4 0.058 13.5 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase MtrF PF09472.10 GAX25200.1 - 0.13 11.7 0.8 0.29 10.6 0.8 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) zinc_ribbon_6 PF14599.6 GAX25201.1 - 9.9e-18 63.9 1.2 9.9e-18 63.9 1.2 3.7 2 1 1 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 GAX25201.1 - 1.9e-16 60.3 16.7 1.9e-16 60.3 16.7 3.9 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 GAX25201.1 - 8.8e-09 35.6 8.0 8.8e-09 35.6 8.0 5.3 4 1 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 GAX25201.1 - 5.5e-07 29.4 4.9 5.5e-07 29.4 4.9 6.1 3 2 1 5 5 5 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAX25201.1 - 0.00033 20.4 10.5 0.00065 19.5 2.0 5.9 4 2 2 6 6 6 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAX25201.1 - 0.0057 16.5 8.0 0.0057 16.5 8.0 5.6 4 3 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX25201.1 - 0.009 15.9 8.2 0.009 15.9 8.2 6.4 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) UBA2_C PF16195.5 GAX25201.1 - 0.18 12.5 8.8 0.34 11.6 8.8 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus YL1 PF05764.13 GAX25201.1 - 3.1 7.9 6.4 3.9 7.5 6.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pes-10 PF07149.11 GAX25201.1 - 4.5 6.2 5.6 5.8 5.9 5.6 1.1 1 0 0 1 1 1 0 Pes-10 AMP-binding PF00501.28 GAX25202.1 - 3.6e-91 305.9 0.0 4.3e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAX25202.1 - 5.6e-20 72.1 2.5 4.9e-18 65.9 0.3 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Thioredoxin PF00085.20 GAX25203.1 - 1e-15 57.5 0.0 1.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX25203.1 - 2.9e-05 24.5 0.0 0.0013 19.2 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAX25203.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 GAX25203.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 GAX25203.1 - 0.086 13.2 0.0 0.8 10.1 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Redoxin PF08534.10 GAX25203.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Redoxin ADK PF00406.22 GAX25205.1 - 3.1e-52 176.7 0.0 4.4e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX25205.1 - 4.2e-22 79.0 0.0 1e-21 77.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 GAX25205.1 - 6.8e-12 45.2 0.0 1.8e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAX25205.1 - 0.0016 18.9 0.0 0.0054 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 GAX25205.1 - 0.0034 17.7 0.6 0.026 14.8 0.2 2.2 1 1 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 GAX25205.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 GAX25205.1 - 0.062 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF445 PF04286.12 GAX25206.1 - 1.3e-15 58.1 2.1 7.2e-07 29.3 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF445) MatE PF01554.18 GAX25206.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 MatE La PF05383.17 GAX25207.1 - 8.8e-11 41.7 0.0 3.3e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 La domain DUF3439 PF11921.8 GAX25207.1 - 5.1 7.1 7.5 14 5.7 7.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mut7-C PF01927.16 GAX25208.1 - 1.3e-19 70.8 1.7 2.8e-19 69.7 1.7 1.5 1 0 0 1 1 1 1 Mut7-C RNAse domain Exo_endo_phos PF03372.23 GAX25208.1 - 3.9e-11 42.9 1.9 4.5e-07 29.6 0.5 2.5 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Methyltransf_32 PF13679.6 GAX25209.1 - 8.2e-20 71.4 0.3 1.8e-19 70.3 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain R3H PF01424.22 GAX25209.1 - 1.1e-06 28.5 0.1 2.8e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 R3H domain TRM13 PF05206.14 GAX25209.1 - 1.2e-06 28.2 0.4 9e-06 25.4 0.4 2.4 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_12 PF08242.12 GAX25209.1 - 9.8e-06 26.2 0.0 2.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX25209.1 - 2.2e-05 24.1 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX25209.1 - 0.0001 22.9 0.0 0.00029 21.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX25209.1 - 0.0017 18.1 0.0 0.0061 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAX25209.1 - 0.011 15.5 0.3 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 Lysine methyltransferase GidB PF02527.15 GAX25209.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.18 GAX25209.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 GAX25209.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAX25209.1 - 0.16 12.6 0.0 0.42 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cwf_Cwc_15 PF04889.12 GAX25210.1 - 0.14 11.9 15.3 0.3 10.8 15.4 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 GAX25210.1 - 0.21 11.1 8.0 0.31 10.6 8.0 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIF_alpha PF05793.12 GAX25210.1 - 0.27 9.8 9.2 0.36 9.4 9.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.14 GAX25210.1 - 0.33 10.7 7.8 0.49 10.2 7.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hus1 PF04005.12 GAX25214.1 - 0.084 12.0 1.5 0.14 11.2 1.5 1.4 1 0 0 1 1 1 0 Hus1-like protein DUF364 PF04016.12 GAX25214.1 - 0.2 11.2 2.1 0.37 10.4 1.4 1.8 1 1 1 2 2 2 0 Putative heavy-metal chelation ERCC3_RAD25_C PF16203.5 GAX25215.1 - 1e-108 362.2 0.1 1e-108 362.2 0.1 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 GAX25215.1 - 9.5e-35 119.5 0.0 2.2e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX25215.1 - 6e-14 52.4 0.0 1.6e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX25215.1 - 2e-11 44.2 0.0 5.1e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 GAX25215.1 - 0.00021 20.1 0.1 0.00057 18.7 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain XRN_M PF17846.1 GAX25216.1 - 0.53 9.2 3.3 1.1 8.2 3.3 1.4 1 0 0 1 1 1 0 Xrn1 helical domain CSN7a_helixI PF18392.1 GAX25216.1 - 3.7 7.5 6.9 40 4.2 2.9 2.8 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain GAT PF03127.14 GAX25217.1 - 0.00016 21.9 0.0 0.0048 17.2 0.0 2.2 2 0 0 2 2 2 1 GAT domain Adaptin_N PF01602.20 GAX25219.1 - 1.1e-82 278.3 1.4 1.6e-82 277.8 1.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 GAX25219.1 - 1.7e-51 173.8 0.1 3.6e-51 172.8 0.1 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 GAX25219.1 - 1.7e-32 112.1 0.3 6e-32 110.3 0.3 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 GAX25219.1 - 1.5e-07 31.7 4.9 0.0001 22.6 0.0 5.3 5 2 2 7 7 7 1 HEAT repeats Cnd1 PF12717.7 GAX25219.1 - 8.4e-07 29.2 5.8 2.9e-05 24.2 0.0 4.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAX25219.1 - 0.0049 16.9 2.6 2 8.6 0.0 5.4 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GAX25219.1 - 0.018 15.2 12.2 0.66 10.4 0.0 6.2 8 0 0 8 8 8 0 HEAT repeat RNA_pol_Rpb1_5 PF04998.17 GAX25219.1 - 0.026 14.0 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Brix PF04427.18 GAX25220.1 - 1.7e-27 96.8 0.3 2.7e-27 96.1 0.3 1.2 1 0 0 1 1 1 1 Brix domain eIF3_subunit PF08597.10 GAX25220.1 - 4.8 7.0 13.5 1.4 8.7 0.1 2.5 2 1 0 2 2 2 0 Translation initiation factor eIF3 subunit Mem_trans PF03547.18 GAX25221.1 - 4.6e-31 107.6 8.5 9.4e-31 106.6 8.5 1.5 1 1 0 1 1 1 1 Membrane transport protein DUF1700 PF08006.11 GAX25221.1 - 0.99 8.9 10.9 3.6 7.1 10.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) MFS_MOT1 PF16983.5 GAX25221.1 - 1 9.8 10.2 2.3 8.6 0.6 3.1 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily Fe_hyd_lg_C PF02906.14 GAX25222.1 - 1.3e-78 264.0 0.0 1.9e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 GAX25222.1 - 2.2e-20 72.5 1.4 4e-20 71.6 1.4 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Methyltransf_16 PF10294.9 GAX25223.1 - 7.6e-19 68.1 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAX25223.1 - 5.3e-11 42.5 0.0 7.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX25223.1 - 3.6e-08 34.0 0.0 6.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX25223.1 - 5.6e-08 32.8 0.0 9.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX25223.1 - 2.2e-07 30.6 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 GAX25223.1 - 1.8e-06 28.5 0.0 2.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX25223.1 - 2.4e-06 27.4 0.0 3.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAX25223.1 - 2.9e-06 27.2 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 GAX25223.1 - 0.00086 20.0 0.0 0.0015 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAX25223.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 GAX25223.1 - 0.002 17.9 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA_U5-meth_tr PF05958.11 GAX25223.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.15 GAX25223.1 - 0.042 13.5 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 GAX25223.1 - 0.14 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.27 GAX25224.1 - 0.00019 22.0 0.0 0.00053 20.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAX25224.1 - 0.056 13.8 0.2 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RNA_pol_3_Rpc31 PF11705.8 GAX25225.1 - 0.0033 17.7 21.5 0.12 12.6 21.5 2.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Mpv17_PMP22 PF04117.12 GAX25226.1 - 9.7e-20 70.6 0.1 1.5e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Afi1 PF07792.12 GAX25227.1 - 0.22 12.0 5.9 0.28 11.7 5.9 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Holin_BhlA PF10960.8 GAX25227.1 - 1.2 9.1 5.2 0.37 10.8 0.5 2.0 2 0 0 2 2 2 0 BhlA holin family Herpes_US12 PF05363.12 GAX25227.1 - 1.6 9.5 4.9 4.5 8.1 1.2 2.1 1 1 1 2 2 2 0 Herpesvirus US12 family MMtag PF10159.9 GAX25227.1 - 7.3 7.0 9.5 5.3 7.4 1.3 2.1 1 1 0 2 2 2 0 Multiple myeloma tumor-associated PBP PF01161.20 GAX25228.1 - 6.7e-33 113.8 0.0 1.3e-32 112.9 0.0 1.4 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein DUF1214 PF06742.11 GAX25228.1 - 0.049 14.1 0.0 0.1 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1214) UCH PF00443.29 GAX25229.1 - 1.3e-41 142.8 0.1 2.8e-41 141.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX25229.1 - 2e-12 47.4 0.5 2.6e-11 43.7 0.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ELO PF01151.18 GAX25230.1 - 1.2e-49 169.1 10.4 1.4e-49 168.9 10.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LapA_dom PF06305.11 GAX25232.1 - 0.00084 19.1 0.6 0.00084 19.1 0.6 3.2 3 1 1 4 4 4 1 Lipopolysaccharide assembly protein A domain Peptidase_U4 PF03419.13 GAX25232.1 - 0.0042 16.4 0.8 0.049 12.9 0.9 2.0 2 0 0 2 2 2 1 Sporulation factor SpoIIGA DUF2681 PF10883.8 GAX25232.1 - 0.025 15.0 6.8 0.032 14.6 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TMEM51 PF15345.6 GAX25232.1 - 0.038 13.8 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Holin_BhlA PF10960.8 GAX25232.1 - 0.044 13.8 2.4 0.11 12.5 2.4 1.6 1 0 0 1 1 1 0 BhlA holin family YajC PF02699.15 GAX25232.1 - 0.045 13.6 0.6 0.045 13.6 0.6 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit SUIM_assoc PF16619.5 GAX25232.1 - 0.11 12.5 12.0 0.21 11.6 12.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4657 PF15552.6 GAX25232.1 - 0.17 11.5 6.3 0.23 11.0 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) EphA2_TM PF14575.6 GAX25232.1 - 0.73 10.8 4.0 3 8.8 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Med3 PF11593.8 GAX25232.1 - 1.9 7.6 7.4 2.4 7.3 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2722 PF10846.8 GAX25232.1 - 3.4 6.5 10.2 4.4 6.1 10.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 GAX25232.1 - 9.3 5.8 11.9 12 5.4 11.9 1.1 1 0 0 1 1 1 0 Spt20 family CIA30 PF08547.12 GAX25233.1 - 3.3e-20 72.7 0.0 4.3e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) zf-CW PF07496.15 GAX25234.1 - 5.1e-14 52.0 6.3 1.2e-13 50.8 6.3 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger SET PF00856.28 GAX25234.1 - 2.1e-07 31.5 5.5 7.5e-07 29.7 0.0 3.8 3 0 0 3 3 3 1 SET domain MBT PF02820.18 GAX25234.1 - 0.1 12.9 1.2 74 3.8 0.0 4.5 5 0 0 5 5 5 0 mbt repeat HMG_box PF00505.19 GAX25234.1 - 0.24 11.9 4.1 0.92 10.0 4.1 2.0 1 0 0 1 1 1 0 HMG (high mobility group) box FliT PF05400.13 GAX25234.1 - 0.42 11.4 3.4 0.64 10.9 0.9 2.7 2 0 0 2 2 2 0 Flagellar protein FliT DUF2749 PF10907.8 GAX25235.1 - 0.025 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Lectin_legB PF00139.19 GAX25235.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Legume lectin domain MoeA_N PF03453.17 GAX25236.1 - 3.3e-27 95.2 0.0 5.7e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 GAX25236.1 - 4.1e-18 65.4 0.0 1e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 GAX25236.1 - 2.1e-10 40.6 0.4 7.9e-10 38.8 0.1 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) MaoC_dehydratas PF01575.19 GAX25240.1 - 1.2e-07 31.4 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 2 MaoC like domain MaoC_dehydrat_N PF13452.6 GAX25240.1 - 0.014 15.5 0.0 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase 4HBT PF03061.22 GAX25240.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Lyase_1 PF00206.20 GAX25242.1 - 6.2e-88 295.2 0.0 1.2e-87 294.3 0.0 1.4 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 GAX25242.1 - 1.1e-25 90.1 0.1 2.6e-25 88.9 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF2680 PF10925.8 GAX25242.1 - 0.23 11.5 1.2 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) SNF2_N PF00176.23 GAX25243.1 - 1e-24 86.9 0.0 1.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX25243.1 - 1.3e-09 38.4 0.0 2.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX25243.1 - 2.2e-05 24.5 0.0 6.9e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Med10 PF09748.9 GAX25244.1 - 0.00038 20.4 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex GDA1_CD39 PF01150.17 GAX25245.1 - 3.8e-77 259.7 0.0 5.2e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ABC1 PF03109.16 GAX25246.1 - 2.4e-19 69.6 0.0 9e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 ABC1 family Thioredoxin PF00085.20 GAX25248.1 - 2.1e-18 66.2 0.0 2.8e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAX25248.1 - 1.4e-06 28.7 0.2 0.001 19.5 0.0 3.0 2 2 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GAX25248.1 - 7.3e-05 22.3 0.0 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 GAX25248.1 - 0.13 12.4 0.1 3.6 7.7 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin domain Glutaredoxin PF00462.24 GAX25248.1 - 0.15 12.3 0.0 0.51 10.6 0.0 1.9 1 0 0 1 1 1 0 Glutaredoxin Cu2_monoox_C PF03712.15 GAX25249.1 - 1e-17 64.1 0.8 1.7e-17 63.4 0.8 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 GAX25249.1 - 1.4e-15 57.6 0.0 4.1e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 DOMON domain Cu2_monooxygen PF01082.20 GAX25249.1 - 1.6e-14 54.2 0.0 3.4e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain AhpC-TSA_2 PF13911.6 GAX25250.1 - 3.1e-15 56.3 0.0 4.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme rhaM PF05336.13 GAX25251.1 - 2.3e-26 91.9 1.3 3.5e-26 91.4 1.3 1.2 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF262 PF03235.14 GAX25253.1 - 0.0096 16.1 1.4 0.15 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function DUF262 Cucumo_2B PF03263.13 GAX25253.1 - 0.078 13.4 0.6 0.18 12.2 0.6 1.6 1 0 0 1 1 1 0 Cucumovirus protein 2B AA_permease_2 PF13520.6 GAX25254.1 - 7.3e-31 107.4 32.0 1e-30 107.0 32.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAX25255.1 - 8e-31 107.3 34.5 8e-31 107.3 34.5 1.3 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAX25255.1 - 1.1e-09 37.5 29.3 1.1e-09 37.5 29.3 1.8 2 1 0 2 2 2 1 Amino acid permease DUF4191 PF13829.6 GAX25255.1 - 0.037 13.4 1.2 0.095 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF2613 PF11021.8 GAX25255.1 - 0.62 10.2 2.7 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Hydrolase_4 PF12146.8 GAX25256.1 - 2.1e-48 164.7 0.0 2.6e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX25256.1 - 3.4e-10 40.0 0.3 3.6e-08 33.4 0.1 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX25256.1 - 8.1e-09 36.4 0.0 1.5e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX25256.1 - 9.6e-06 25.2 0.0 0.0098 15.4 0.0 2.4 1 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAX25256.1 - 0.00013 21.8 0.0 2 8.2 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.20 GAX25256.1 - 0.0021 17.7 0.0 0.0036 17.0 0.0 1.5 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 GAX25256.1 - 0.043 13.5 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) ANF_receptor PF01094.28 GAX25256.1 - 0.076 12.1 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 Receptor family ligand binding region PGAP1 PF07819.13 GAX25256.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 GAX25256.1 - 0.12 12.2 0.0 0.76 9.6 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Alpha_kinase PF02816.18 GAX25257.1 - 2.5e-42 145.1 0.0 3.7e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Tudor_3 PF18115.1 GAX25257.1 - 0.0056 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TPR_14 PF13428.6 GAX25257.1 - 0.27 12.2 1.6 1.8 9.6 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Hist_deacetyl PF00850.19 GAX25258.1 - 6.3e-65 219.6 0.0 2e-63 214.8 0.0 2.3 2 0 0 2 2 2 1 Histone deacetylase domain Ank_4 PF13637.6 GAX25258.1 - 5.4e-13 49.2 0.3 4.4e-07 30.3 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX25258.1 - 9e-13 48.6 0.0 1.7e-11 44.5 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX25258.1 - 2.4e-12 46.7 0.6 0.00014 22.1 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Myb_DNA-binding PF00249.31 GAX25258.1 - 1.9e-10 40.7 0.3 3.5e-10 39.9 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ank_5 PF13857.6 GAX25258.1 - 7.9e-10 38.8 0.4 1.8e-07 31.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX25258.1 - 2.5e-09 36.6 0.1 0.0018 18.6 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Myb_DNA-bind_6 PF13921.6 GAX25258.1 - 0.03 14.6 0.1 0.06 13.6 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX25258.1 - 0.033 14.1 0.2 0.073 13.0 0.2 1.5 1 0 0 1 1 1 0 Myb DNA-binding like GatB_N PF02934.15 GAX25259.1 - 1.4e-88 296.8 0.0 2.2e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 GAX25259.1 - 4.3e-20 72.1 0.0 9.2e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 GatB domain PT PF04886.12 GAX25260.1 - 0.0094 15.5 18.4 0.25 10.9 7.3 3.0 1 1 1 2 2 2 2 PT repeat DUF4381 PF14316.6 GAX25260.1 - 0.027 14.7 0.1 0.066 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ribosomal_S2 PF00318.20 GAX25260.1 - 0.18 11.0 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 PP2C PF00481.21 GAX25261.1 - 4.2e-49 167.5 0.0 5.4e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX25261.1 - 0.015 15.2 0.3 0.15 12.0 0.3 2.1 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) DUF3782 PF12644.7 GAX25262.1 - 0.068 13.3 5.1 0.37 11.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) Pro_isomerase PF00160.21 GAX25263.1 - 3.5e-43 147.6 0.0 6.4e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bromodomain PF00439.25 GAX25264.1 - 4.1e-64 212.6 1.2 5.1e-21 74.5 0.1 3.7 3 0 0 3 3 3 3 Bromodomain SNF2_N PF00176.23 GAX25264.1 - 1.3e-55 188.5 0.1 2.6e-55 187.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX25264.1 - 5.5e-20 71.8 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 GAX25264.1 - 7.7e-15 54.5 0.8 7.2e-09 35.4 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HMG_box PF00505.19 GAX25264.1 - 2.6e-12 47.0 2.2 8.3e-12 45.4 2.2 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box ResIII PF04851.15 GAX25264.1 - 3.1e-07 30.6 0.0 1.3e-06 28.5 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box_2 PF09011.10 GAX25264.1 - 1.8e-06 28.4 1.2 7.6e-06 26.4 1.2 2.2 1 0 0 1 1 1 1 HMG-box domain PHD PF00628.29 GAX25264.1 - 2.1e-05 24.3 12.4 4.5e-05 23.2 12.4 1.6 1 0 0 1 1 1 1 PHD-finger HDA2-3 PF11496.8 GAX25264.1 - 3e-05 23.3 0.1 0.00019 20.7 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAX25264.1 - 0.0011 18.7 0.0 0.0042 16.9 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDNT PF08073.12 GAX25264.1 - 0.004 17.1 0.0 0.004 17.1 0.0 2.3 2 0 0 2 2 1 1 CHDNT (NUC034) domain ERCC3_RAD25_C PF16203.5 GAX25264.1 - 0.0091 15.2 0.0 0.025 13.8 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PDZ_6 PF17820.1 GAX25264.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DENN PF02141.21 GAX25265.1 - 3.8e-44 150.9 6.6 6.9e-44 150.0 6.6 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAX25265.1 - 4e-18 65.9 1.1 3.2e-17 63.0 0.5 2.7 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 GAX25265.1 - 6.9e-08 32.4 3.9 1.7e-07 31.1 3.9 1.8 1 0 0 1 1 1 1 dDENN domain PPR PF01535.20 GAX25265.1 - 0.00016 21.7 0.1 0.00043 20.3 0.1 1.8 1 0 0 1 1 1 1 PPR repeat zinc_ribbon_9 PF14369.6 GAX25265.1 - 0.011 16.0 2.7 0.96 9.8 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon PPR_1 PF12854.7 GAX25265.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 PPR repeat SPA PF08616.10 GAX25265.1 - 0.16 11.9 0.1 0.44 10.5 0.1 1.7 1 0 0 1 1 1 0 Stabilization of polarity axis Abhydrolase_2 PF02230.16 GAX25266.1 - 3.3e-06 27.1 0.0 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAX25266.1 - 0.008 16.8 0.2 0.012 16.2 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2235 PF09994.9 GAX25266.1 - 0.073 12.4 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) PseudoU_synth_2 PF00849.22 GAX25267.1 - 1.7e-26 93.2 0.0 5.5e-26 91.6 0.0 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase TRIC PF05197.13 GAX25268.1 - 4.6e-08 32.9 0.4 6.5e-08 32.4 0.4 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 GAX25268.1 - 0.01 15.7 0.6 0.029 14.3 0.6 1.7 1 0 0 1 1 1 0 UPF0126 domain PUF PF00806.19 GAX25269.1 - 3.7e-50 164.9 10.7 1.1e-06 27.9 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat RuvC_III PF18541.1 GAX25269.1 - 0.11 12.4 0.8 0.21 11.5 0.8 1.3 1 0 0 1 1 1 0 RuvC endonuclease subdomain 3 GTP_EFTU PF00009.27 GAX25270.1 - 1.7e-66 223.5 0.0 2.5e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAX25270.1 - 2.3e-42 143.6 0.1 4.3e-42 142.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 GAX25270.1 - 1e-34 118.5 0.1 2.4e-34 117.3 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAX25270.1 - 3.1e-25 88.0 0.0 7.7e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX25270.1 - 3.4e-16 59.4 3.1 5.3e-16 58.8 1.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAX25270.1 - 3.6e-07 30.0 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAX25270.1 - 0.00069 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAX25270.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 AIG1 family TDP43_N PF18694.1 GAX25270.1 - 0.16 11.8 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain CK_II_beta PF01214.18 GAX25271.1 - 1.6e-27 96.5 0.0 2.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FYVE PF01363.21 GAX25274.1 - 4.6e-11 42.7 10.1 7.2e-11 42.1 10.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger Ank_2 PF12796.7 GAX25274.1 - 0.00032 21.2 0.0 0.0008 19.9 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX25274.1 - 0.0014 19.1 0.0 0.093 13.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX25274.1 - 0.019 15.3 0.0 2.4 8.6 0.0 2.5 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX25274.1 - 0.021 15.3 0.0 0.43 11.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat FYVE_2 PF02318.16 GAX25274.1 - 0.18 12.1 8.8 0.32 11.2 8.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 GAX25275.1 - 1.6e-11 44.1 8.7 1.6e-11 44.1 8.7 2.6 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 GAX25275.1 - 1.7e-06 27.7 23.0 1.7e-06 27.7 23.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 GAX25275.1 - 0.00057 20.4 0.0 1.6 9.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX25275.1 - 0.0042 17.5 0.0 1.3 9.8 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 GAX25275.1 - 0.011 16.3 0.0 0.033 14.8 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FYVE_2 PF02318.16 GAX25275.1 - 0.013 15.7 6.7 0.013 15.7 6.7 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 GAX25276.1 - 2.3e-06 27.6 8.3 2.3e-06 27.6 8.3 2.9 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 GAX25276.1 - 2.4e-06 27.3 25.3 2.4e-06 27.3 25.3 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 GAX25276.1 - 0.00063 20.0 0.0 0.09 13.1 0.0 3.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX25276.1 - 0.0056 17.2 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX25276.1 - 0.0085 16.5 0.0 1.1 10.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 GAX25276.1 - 0.065 13.8 0.0 0.39 11.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF155 PF02582.14 GAX25277.1 - 2.1e-41 141.9 0.3 3e-41 141.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Na_H_Exchanger PF00999.21 GAX25278.1 - 4.3e-50 170.6 29.4 9.2e-48 162.9 28.4 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family GTP_EFTU PF00009.27 GAX25279.1 - 2.5e-52 177.3 0.1 2.8e-52 177.1 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAX25279.1 - 0.0017 18.4 0.1 0.0038 17.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAX25279.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MobB PF03205.14 GAX25279.1 - 0.072 13.0 0.3 5.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B EFG_IV PF03764.18 GAX25280.1 - 2.9e-37 127.1 0.3 3.8e-36 123.5 0.1 2.6 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.6 GAX25280.1 - 2.3e-32 110.9 0.1 5.2e-32 109.8 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAX25280.1 - 3.6e-25 87.8 0.1 1.9e-24 85.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAX25280.1 - 1.6e-11 44.4 0.3 3e-10 40.4 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAX25280.1 - 1.9e-08 34.2 0.0 5.4e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SBDS_C PF09377.10 GAX25280.1 - 0.0062 16.6 0.0 0.02 14.9 0.0 1.8 2 0 0 2 2 2 1 SBDS protein C-terminal domain NFACT-R_1 PF05670.13 GAX25281.1 - 6.9e-34 116.8 0.1 1.2e-33 116.0 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF4340 PF14238.6 GAX25281.1 - 0.13 12.3 1.9 0.18 11.8 0.7 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4340) ANAPC4_WD40 PF12894.7 GAX25282.1 - 4.4e-13 49.3 0.0 0.35 11.2 0.1 5.5 4 2 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAX25282.1 - 7.1e-12 45.7 15.0 0.075 13.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAX25282.1 - 0.00013 21.1 0.2 0.58 9.0 0.0 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAX25282.1 - 0.0042 17.0 0.1 3.5 7.7 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat SGL PF08450.12 GAX25282.1 - 0.058 13.0 0.1 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region eIF2A PF08662.11 GAX25282.1 - 0.17 11.7 0.0 2.9 7.7 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Guanylate_kin PF00625.21 GAX25283.1 - 1.2e-50 171.7 0.0 1.5e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 GAX25283.1 - 0.00076 19.7 0.0 0.0017 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX25283.1 - 0.008 16.7 0.3 0.24 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAX25283.1 - 0.0093 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 GAX25283.1 - 0.046 14.1 0.0 0.093 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAX25283.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX25283.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Glyco_hydro_31 PF01055.26 GAX25285.1 - 2e-138 462.3 3.4 3.1e-138 461.7 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAX25285.1 - 1.3e-22 79.9 1.0 1.6e-21 76.4 0.1 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like PTPLA PF04387.14 GAX25286.1 - 3.4e-39 134.2 5.7 6.1e-39 133.4 5.7 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Sua5_yciO_yrdC PF01300.18 GAX25287.1 - 6e-43 146.4 0.0 8.4e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 GAX25287.1 - 9.2e-13 48.9 0.0 2.5e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding PseudoU_synth_2 PF00849.22 GAX25288.1 - 3.1e-24 85.9 0.0 5.7e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase PsbP PF01789.16 GAX25289.1 - 3.8e-15 56.4 0.2 5.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 PsbP DnaJ PF00226.31 GAX25290.1 - 3.7e-11 43.0 0.0 9.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain IGR PF09597.10 GAX25290.1 - 0.046 13.8 0.6 7.1 6.8 0.1 3.1 2 1 0 2 2 2 0 IGR protein motif SNAD4 PF18750.1 GAX25290.1 - 0.1 12.7 0.1 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 QueF_N PF14819.6 GAX25290.1 - 0.13 12.6 0.0 1 9.7 0.0 2.0 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term TatD_DNase PF01026.21 GAX25291.1 - 2.5e-42 145.0 0.0 3.3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Defensin_5 PF18251.1 GAX25291.1 - 0.1 12.7 2.9 1.7 8.8 0.3 2.3 2 0 0 2 2 2 0 Fungal defensin Copsin Sulfotransfer_2 PF03567.14 GAX25292.1 - 7.6e-21 75.2 0.0 1.3e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family p450 PF00067.22 GAX25293.1 - 4.6e-61 207.0 0.4 6.1e-61 206.6 0.4 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cas1_AcylT PF07779.12 GAX25294.1 - 3.4e-60 204.3 20.2 2e-59 201.8 20.1 1.8 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p HNH_3 PF13392.6 GAX25295.1 - 4.8e-05 23.0 3.6 0.0044 16.7 0.1 2.7 2 0 0 2 2 2 2 HNH endonuclease KH_6 PF15985.5 GAX25296.1 - 2.4e-11 43.8 0.0 4.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 GAX25296.1 - 2.4e-09 36.8 1.4 2.7e-08 33.5 1.4 2.4 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PIP5K PF01504.18 GAX25297.1 - 1.6e-38 132.6 7.6 1.1e-31 110.1 0.0 3.1 3 1 1 4 4 4 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 GAX25297.1 - 7.8e-27 94.0 0.1 1.4e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 GAX25297.1 - 1.8e-10 40.8 12.8 1.8e-10 40.8 12.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 GAX25297.1 - 0.0011 19.2 5.8 0.004 17.4 5.8 2.0 1 0 0 1 1 1 1 FYVE-type zinc finger DUF4527 PF15030.6 GAX25297.1 - 0.0021 17.6 0.3 0.0057 16.1 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4527) Rpr2 PF04032.16 GAX25297.1 - 2 8.7 7.3 3.7 7.9 3.5 3.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GGACT PF06094.12 GAX25298.1 - 0.0083 16.7 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 GAX25298.1 - 0.11 12.8 0.0 0.42 11.0 0.0 1.8 1 1 0 1 1 1 0 AIG2-like family Complex1_LYR PF05347.15 GAX25299.1 - 2.3e-09 37.2 0.2 5.2e-09 36.0 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAX25299.1 - 0.0036 18.0 0.4 0.0059 17.3 0.4 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Exo70 PF03081.15 GAX25301.1 - 2e-38 132.4 1.6 2e-38 132.4 0.3 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit COG6 PF06419.11 GAX25301.1 - 0.1 10.8 4.0 2.4 6.3 0.2 2.6 2 1 0 2 2 2 0 Conserved oligomeric complex COG6 DUF948 PF06103.11 GAX25301.1 - 0.13 12.5 4.0 1 9.6 0.0 3.9 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) HEAT_2 PF13646.6 GAX25302.1 - 0.077 13.4 0.5 0.79 10.2 0.2 2.7 3 0 0 3 3 3 0 HEAT repeats Pyr_redox_2 PF07992.14 GAX25303.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_1 PF00561.20 GAX25305.1 - 0.0026 17.5 0.0 0.0058 16.3 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 GAX25305.1 - 0.039 13.5 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 GAX25305.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_M23 PF01551.22 GAX25306.1 - 4.9e-16 58.7 0.2 6.5e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M23 Abhydrolase_6 PF12697.7 GAX25307.1 - 0.0054 17.4 0.0 0.037 14.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAX25307.1 - 0.027 14.0 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF829 PF05705.14 GAX25307.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) IL12 PF03039.14 GAX25308.1 - 1.3 8.3 4.5 2.3 7.5 4.5 1.3 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Dicty_CTDC PF00526.18 GAX25308.1 - 2.9 7.9 61.4 0.051 13.5 3.6 7.5 7 1 0 7 7 7 0 Dictyostelium (slime mold) repeat HA2 PF04408.23 GAX25309.1 - 1.4e-16 60.8 0.0 1.4e-16 60.8 0.0 3.2 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX25309.1 - 1.2e-10 41.6 0.0 3.6e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX25309.1 - 6.2e-10 39.4 0.0 3.8e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX25309.1 - 1.8e-05 24.6 0.4 8.1e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX25309.1 - 0.014 15.6 4.6 0.015 15.6 0.4 3.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAX25309.1 - 0.018 14.7 0.4 0.063 13.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX25309.1 - 0.042 14.3 0.0 0.042 14.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 GAX25309.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.18 GAX25309.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1382 PF07131.11 GAX25309.1 - 0.59 10.2 2.5 1.8 8.6 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Mito_carr PF00153.27 GAX25310.1 - 1.6e-41 140.1 1.6 1.8e-20 72.7 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1772 PF08592.11 GAX25310.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) WW PF00397.26 GAX25311.1 - 7.1e-16 58.0 8.6 2e-07 30.9 0.4 2.5 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 GAX25311.1 - 0.067 13.5 1.3 2.4 8.5 0.2 2.4 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain WW PF00397.26 GAX25312.1 - 1.8e-21 75.9 18.0 2.7e-07 30.5 1.2 3.7 3 0 0 3 3 3 3 WW domain Glyco_hyd_101C PF17451.2 GAX25312.1 - 1.8e-05 25.0 5.6 0.76 10.1 0.0 3.9 4 0 0 4 4 4 3 Glycosyl hydrolase 101 beta sandwich domain PQQ_2 PF13360.6 GAX25312.1 - 0.001 18.7 0.5 0.16 11.5 0.1 2.1 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 GAX25312.1 - 0.042 13.8 0.5 4.4 7.4 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Ysc84 PF04366.12 GAX25313.1 - 2.8e-21 75.6 0.4 3.9e-21 75.1 0.4 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator PH PF00169.29 GAX25314.1 - 1.8e-09 38.0 0.0 8.4e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 GAX25314.1 - 0.0097 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain bZIP_2 PF07716.15 GAX25314.1 - 2.1 8.5 7.5 9 6.5 1.5 3.1 2 0 0 2 2 2 0 Basic region leucine zipper SLX9 PF15341.6 GAX25314.1 - 4.9 7.6 12.6 36 4.8 3.3 3.2 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 Csm1_N PF18504.1 GAX25314.1 - 4.9 7.6 14.3 0.31 11.4 4.0 3.1 3 0 0 3 3 3 0 Csm1 N-terminal domain SlyX PF04102.12 GAX25314.1 - 6.2 7.5 8.1 3.9 8.2 0.6 3.9 3 0 0 3 3 3 0 SlyX V_ATPase_I PF01496.19 GAX25314.1 - 8.9 4.1 8.8 3.6 5.4 6.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family GTP_EFTU PF00009.27 GAX25315.1 - 9.3e-44 149.3 0.0 1.7e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAX25315.1 - 1.1e-20 74.0 0.3 4.6e-20 72.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAX25315.1 - 4.2e-09 36.7 0.1 1.4e-08 35.0 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAX25315.1 - 0.00038 20.5 0.1 0.003 17.6 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase HEAT_2 PF13646.6 GAX25316.1 - 0.00045 20.6 1.9 0.24 11.8 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 GAX25316.1 - 0.00047 20.2 6.1 0.088 13.1 0.1 4.9 5 0 0 5 5 5 1 HEAT repeat MMS19_N PF14500.6 GAX25316.1 - 0.013 15.1 1.8 0.072 12.7 0.1 2.7 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF5523 PF17661.1 GAX25316.1 - 0.082 12.6 14.0 0.13 11.9 14.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4670 PF15709.5 GAX25316.1 - 0.31 10.3 27.3 0.48 9.7 27.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) SpoIIE PF07228.12 GAX25317.1 - 3.3e-08 33.7 0.0 4.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) WW PF00397.26 GAX25317.1 - 5e-06 26.5 0.1 1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 WW domain PP2C PF00481.21 GAX25317.1 - 9.7e-06 25.4 0.0 0.019 14.6 0.1 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAX25317.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C DUF2076 PF09849.9 GAX25317.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SGS PF05002.15 GAX25318.1 - 6.1e-32 109.6 5.5 1.6e-31 108.2 5.5 1.8 1 0 0 1 1 1 1 SGS domain TPR_2 PF07719.17 GAX25318.1 - 3e-12 45.7 5.9 0.0037 17.3 0.9 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.16 GAX25318.1 - 8.5e-12 45.9 0.1 1.7e-11 45.0 0.1 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 GAX25318.1 - 1.7e-09 37.1 2.1 0.0066 16.2 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAX25318.1 - 1.5e-06 28.4 9.1 1.9e-05 24.9 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25318.1 - 0.00044 20.8 8.2 0.23 12.1 0.4 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat XS PF03468.14 GAX25318.1 - 0.0049 17.1 0.0 0.019 15.3 0.0 1.9 1 0 0 1 1 1 1 XS domain TPR_14 PF13428.6 GAX25318.1 - 0.007 17.1 6.1 16 6.6 1.3 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX25318.1 - 0.023 15.2 0.4 5.4 7.6 0.0 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25318.1 - 0.025 14.6 1.8 0.13 12.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25318.1 - 0.072 13.3 2.4 10 6.6 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX25318.1 - 3.4 7.4 5.3 10 5.9 0.0 3.1 3 0 0 3 3 3 0 TPR repeat DUF2057 PF09829.9 GAX25318.1 - 4.2 7.5 10.0 0.17 12.0 1.0 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_6 PF13174.6 GAX25318.1 - 6 7.7 8.6 38 5.2 1.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Polyketide_cyc2 PF10604.9 GAX25319.1 - 1.7e-06 28.4 0.1 3.1e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX25319.1 - 8.4e-06 26.0 0.0 1.1e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4336 PF14234.6 GAX25321.1 - 1.2e-116 389.4 0.0 1.6e-116 389.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) RRM_1 PF00076.22 GAX25322.1 - 5e-26 90.3 0.1 6.8e-14 51.4 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX25322.1 - 1.1e-05 25.4 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 GAX25322.1 - 0.0014 18.4 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RBM39linker PF15519.6 GAX25322.1 - 0.065 14.3 0.3 1.3 10.1 0.0 2.6 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Peptidase_M17 PF00883.21 GAX25323.1 - 1.3e-108 362.9 0.2 1.9e-108 362.5 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF1177 PF06675.11 GAX25323.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) Pyridoxal_deC PF00282.19 GAX25324.1 - 6.2e-28 97.6 0.0 1.3e-27 96.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAX25324.1 - 1.9e-05 23.8 0.0 3.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAX25324.1 - 0.0027 16.9 0.0 0.011 14.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 GAX25324.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Aquarius_N PF16399.5 GAX25325.1 - 7.8e-90 302.1 0.0 1.2e-89 301.5 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 GAX25325.1 - 7.5e-31 107.3 0.0 1.2e-29 103.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAX25325.1 - 7.9e-27 94.7 0.0 2.2e-26 93.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX25325.1 - 2e-07 30.9 0.0 0.00023 21.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAX25325.1 - 2.3e-07 31.3 0.0 2.2e-06 28.1 0.0 2.5 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 GAX25325.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAX25325.1 - 0.0061 16.1 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 GAX25325.1 - 0.0082 16.0 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.29 GAX25325.1 - 0.013 16.0 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 GAX25325.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 GAX25325.1 - 0.037 13.5 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 GAX25325.1 - 0.066 13.5 0.1 0.58 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAX25325.1 - 0.071 12.3 0.6 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 GAX25325.1 - 0.08 12.7 0.0 4.1 7.1 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 GAX25325.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 GAX25325.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase NDUFA12 PF05071.16 GAX25326.1 - 5.6e-16 59.2 4.5 8.1e-16 58.6 1.4 2.1 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Amidohydro_1 PF01979.20 GAX25327.1 - 8.8e-32 110.8 0.1 2e-31 109.6 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAX25327.1 - 8.4e-13 48.6 1.0 0.00031 20.3 0.1 3.1 3 0 0 3 3 3 3 Amidohydrolase family Cytochrom_C1 PF02167.15 GAX25328.1 - 3.3e-87 291.8 0.0 3.8e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GAX25328.1 - 0.0026 18.0 0.0 0.0069 16.7 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III FGE-sulfatase PF03781.16 GAX25331.1 - 1.1e-29 103.9 3.5 1.9e-29 103.0 3.5 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_23 PF13489.6 GAX25331.1 - 7.2e-13 48.7 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX25331.1 - 9.3e-08 32.7 0.0 1.1e-05 26.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX25331.1 - 6.1e-07 29.4 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GAX25331.1 - 1.3e-06 29.0 0.0 5.7e-05 23.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain DinB_2 PF12867.7 GAX25331.1 - 4.5e-06 27.2 0.0 1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 DinB superfamily Methyltransf_11 PF08241.12 GAX25331.1 - 9.1e-06 26.2 0.0 0.00011 22.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX25331.1 - 0.01 15.4 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 GAX25331.1 - 0.066 12.3 0.0 1.3 8.0 0.0 2.5 2 1 0 2 2 2 0 DREV methyltransferase YfaZ PF07437.11 GAX25332.1 - 0.042 13.5 0.2 0.06 13.0 0.2 1.2 1 0 0 1 1 1 0 YfaZ precursor Palm_thioest PF02089.15 GAX25332.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PPR_2 PF13041.6 GAX25333.1 - 6.5e-36 122.3 0.8 2e-06 27.9 0.0 9.0 7 2 1 8 8 8 7 PPR repeat family PPR_1 PF12854.7 GAX25333.1 - 5.2e-28 96.4 10.1 0.00022 20.8 0.0 11.8 12 0 0 12 12 12 9 PPR repeat PPR_3 PF13812.6 GAX25333.1 - 1.1e-26 92.6 0.1 0.0012 18.9 0.0 8.4 6 2 3 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX25333.1 - 6e-13 48.7 0.7 2.7e-06 26.9 0.0 4.2 1 1 3 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX25333.1 - 2.1e-08 33.8 29.4 0.014 15.6 0.1 11.4 13 1 0 13 13 13 3 PPR repeat YbfN PF13982.6 GAX25333.1 - 0.095 13.0 0.0 3 8.2 0.0 3.0 3 0 0 3 3 3 0 YbfN-like lipoprotein Calici_PP_N PF08405.11 GAX25333.1 - 0.13 11.0 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal TPR_14 PF13428.6 GAX25333.1 - 0.26 12.2 9.5 2.5 9.2 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 GAX25334.1 - 6.4e-09 35.7 1.0 1.3e-08 34.7 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 GAX25334.1 - 0.0039 17.1 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase HlyD_3 PF13437.6 GAX25334.1 - 0.056 14.2 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 HlyD family secretion protein FAD_binding_4 PF01565.23 GAX25335.1 - 2.9e-11 43.2 0.6 5.4e-11 42.4 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 GAX25335.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 GAX25336.1 - 1.3e-07 31.4 0.2 3e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DUF1896 PF08989.10 GAX25336.1 - 0.14 12.3 0.0 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) FAD_binding_4 PF01565.23 GAX25337.1 - 5.7e-10 39.1 1.3 1.1e-09 38.2 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 GAX25337.1 - 1.7e-05 24.7 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DUF4936 PF16290.5 GAX25337.1 - 0.17 12.6 0.0 0.5 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) PCEMA1 PF07418.11 GAX25338.1 - 0.0057 16.2 0.1 0.0057 16.2 0.1 1.2 1 0 0 1 1 1 1 Acidic phosphoprotein precursor PCEMA1 MORN PF02493.20 GAX25339.1 - 0.024 14.5 4.0 0.13 12.2 1.7 2.8 2 0 0 2 2 2 0 MORN repeat ESSS PF10183.9 GAX25340.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NOA36 PF06524.12 GAX25340.1 - 0.26 10.6 5.1 0.28 10.5 5.1 1.1 1 0 0 1 1 1 0 NOA36 protein Spb1_C PF07780.12 GAX25341.1 - 5.5e-52 176.5 17.0 5.5e-52 176.5 17.0 4.8 3 3 3 6 6 6 1 Spb1 C-terminal domain FtsJ PF01728.19 GAX25341.1 - 2.8e-46 157.9 0.0 7.6e-46 156.4 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 GAX25341.1 - 1.1e-26 93.6 15.3 1.1e-26 93.6 15.3 5.1 4 2 0 4 4 4 1 Domain of unknown function (DUF3381) Thioredoxin PF00085.20 GAX25342.1 - 6.5e-17 61.4 0.0 1e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX25342.1 - 1.5e-11 44.5 0.0 1e-08 35.4 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX25342.1 - 3.3e-07 30.7 0.0 5.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 GAX25342.1 - 1.5e-05 25.0 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX25342.1 - 2.3e-05 24.5 0.0 5.7e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 GAX25342.1 - 2.4e-05 24.3 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 GAX25342.1 - 5.9e-05 23.0 0.0 9.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAX25342.1 - 0.00052 19.8 0.0 0.0018 18.0 0.0 1.9 1 1 0 1 1 1 1 Redoxin Thioredoxin_5 PF13743.6 GAX25342.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin Bromodomain PF00439.25 GAX25343.1 - 5.1e-21 74.5 0.2 1e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 GAX25343.1 - 1.5e-06 28.2 0.7 2.3e-06 27.7 0.7 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Sec2p PF06428.11 GAX25343.1 - 0.071 13.1 2.5 0.15 12.0 2.5 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p UPF0489 PF12640.7 GAX25344.1 - 2.5e-25 89.7 4.7 9.2e-25 87.9 4.7 1.9 1 1 0 1 1 1 1 UPF0489 domain APS_kinase PF01583.20 GAX25345.1 - 3.4e-58 196.0 0.0 6.5e-58 195.1 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 GAX25345.1 - 2.8e-47 160.9 0.0 4.9e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 GAX25345.1 - 2e-44 151.2 0.0 3.1e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 GAX25345.1 - 5.6e-36 123.6 0.0 4.7e-35 120.6 0.0 2.5 3 0 0 3 3 3 1 PUA-like domain AAA_33 PF13671.6 GAX25345.1 - 4e-06 27.0 0.0 1.6e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX25345.1 - 0.00032 21.2 0.1 0.0016 19.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX25345.1 - 0.0011 18.3 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 GAX25345.1 - 0.025 14.8 0.6 0.1 12.8 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX25345.1 - 0.032 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX25345.1 - 0.069 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 GAX25345.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 GAX25345.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FA_desaturase PF00487.24 GAX25346.1 - 2.6e-20 73.3 16.2 4e-20 72.7 16.1 1.4 1 1 0 1 1 1 1 Fatty acid desaturase zf-RING_6 PF14835.6 GAX25347.1 - 1.3e-07 31.4 5.9 2.2e-07 30.6 5.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 GAX25347.1 - 1.5e-05 24.8 17.6 1.5e-05 24.8 17.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX25347.1 - 1.8e-05 24.5 16.8 1.8e-05 24.5 16.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX25347.1 - 4.1e-05 23.5 13.0 4.1e-05 23.5 13.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 GAX25347.1 - 0.0035 17.4 10.5 0.0054 16.9 10.5 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 GAX25347.1 - 0.0059 16.6 16.5 0.0059 16.6 16.5 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAX25347.1 - 0.008 16.3 16.1 0.008 16.3 16.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GAX25347.1 - 0.014 15.3 14.5 0.015 15.2 13.5 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX25347.1 - 0.024 15.0 15.8 0.024 15.0 15.8 1.8 2 0 0 2 2 2 0 Ring finger domain zf-Nse PF11789.8 GAX25347.1 - 0.065 13.1 7.3 0.17 11.7 7.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Sigma70_r1_2 PF00140.20 GAX25347.1 - 0.15 12.1 1.3 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Prok-RING_4 PF14447.6 GAX25347.1 - 0.95 9.4 16.1 1.2 9.0 14.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAX25347.1 - 3.1 8.2 15.5 0.83 10.0 10.2 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain DUF938 PF06080.12 GAX25348.1 - 1.3e-58 198.1 0.0 1.6e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 GAX25348.1 - 0.064 14.0 0.0 0.17 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Myosin_head PF00063.21 GAX25349.1 - 2.9e-212 706.6 0.0 6.2e-212 705.5 0.0 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 GAX25349.1 - 2.3e-08 33.1 24.3 0.026 14.3 0.1 5.8 4 1 1 5 5 5 5 IQ calmodulin-binding motif SlyX PF04102.12 GAX25349.1 - 0.007 17.0 4.0 0.007 17.0 4.0 4.5 2 2 1 3 3 3 1 SlyX Spc7 PF08317.11 GAX25349.1 - 0.29 10.0 33.1 0.019 13.9 15.7 2.9 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 GAX25349.1 - 1 9.7 19.9 0.95 9.8 11.5 3.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4795 PF16043.5 GAX25349.1 - 3.2 7.3 32.8 1.8 8.1 8.0 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) Fasciclin PF02469.22 GAX25350.1 - 5.7e-11 42.7 0.0 7.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Peptidase_M17 PF00883.21 GAX25351.1 - 1e-108 363.3 0.8 1.5e-108 362.8 0.8 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 GAX25351.1 - 1.1e-08 34.9 0.1 3.7e-08 33.3 0.1 1.9 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Sof1 PF04158.14 GAX25351.1 - 0.045 14.0 0.0 0.21 11.8 0.0 2.2 3 0 0 3 3 3 0 Sof1-like domain DUF913 PF06025.12 GAX25351.1 - 0.17 10.8 0.3 2.4 7.0 0.0 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) RRM_1 PF00076.22 GAX25352.1 - 3.7e-18 65.1 0.0 5.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX25352.1 - 0.049 13.2 0.0 0.089 12.4 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 GAX25352.1 - 0.057 13.1 0.4 0.096 12.4 0.4 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain RRM_occluded PF16842.5 GAX25352.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif Metallophos PF00149.28 GAX25353.1 - 1.3e-24 87.9 1.2 1.3e-24 87.9 0.2 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase BAR_3 PF16746.5 GAX25353.1 - 0.088 12.5 0.9 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 BAR domain of APPL family SQS_PSY PF00494.19 GAX25355.1 - 1.3e-60 205.1 0.5 2e-60 204.5 0.5 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Exotox-A_cataly PF09009.10 GAX25355.1 - 0.0076 16.0 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Exotoxin A catalytic FKBP_C PF00254.28 GAX25356.1 - 3.7e-28 97.7 0.0 4.7e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PC4 PF02229.16 GAX25357.1 - 1e-22 79.5 0.2 1.5e-22 78.9 0.2 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) HMG14_17 PF01101.18 GAX25357.1 - 0.044 14.7 3.4 0.066 14.2 3.4 1.3 1 0 0 1 1 1 0 HMG14 and HMG17 FAM176 PF14851.6 GAX25357.1 - 0.23 11.1 3.7 0.37 10.5 3.7 1.3 1 0 0 1 1 1 0 FAM176 family Alg6_Alg8 PF03155.15 GAX25358.1 - 1.6e-99 334.1 24.9 2.5e-99 333.5 24.9 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family zf-HC5HC2H_2 PF13832.6 GAX25359.1 - 1.3e-22 80.1 40.8 1.4e-12 47.7 6.4 5.2 5 0 0 5 5 5 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAX25359.1 - 1.4e-14 54.1 19.5 2.4e-11 43.7 3.2 5.8 3 2 2 6 6 6 3 PHD-like zinc-binding domain PHD_2 PF13831.6 GAX25359.1 - 4.7e-10 38.9 4.7 4.7e-10 38.9 4.7 4.7 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 GAX25359.1 - 2e-09 37.2 5.1 2e-09 37.2 5.1 5.4 6 0 0 6 6 6 3 PHD-finger C1_1 PF00130.22 GAX25359.1 - 0.0068 16.3 0.5 0.0068 16.3 0.5 6.0 5 2 1 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 GAX25359.1 - 0.23 11.4 4.0 0.61 10.2 4.0 1.8 1 0 0 1 1 1 0 AT hook motif Ank_2 PF12796.7 GAX25360.1 - 2e-21 76.4 0.1 1.1e-10 41.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX25360.1 - 3.1e-16 59.5 0.0 5.5e-05 23.6 0.1 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX25360.1 - 4.8e-16 58.6 0.1 5.2e-08 33.0 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 GAX25360.1 - 6e-14 51.9 21.0 8.6e-14 51.3 21.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 GAX25360.1 - 2e-13 49.2 0.0 0.00092 19.5 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAX25360.1 - 8e-13 48.2 0.0 0.00013 22.3 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ion_trans_2 PF07885.16 GAX25360.1 - 4.1e-10 39.5 12.0 4.1e-10 39.5 12.0 2.1 2 1 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 GAX25360.1 - 2.8e-07 30.5 0.0 4.1e-06 26.8 0.0 2.5 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain IRK PF01007.20 GAX25360.1 - 8.9 6.1 11.6 0.58 10.0 5.9 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF3464 PF11947.8 GAX25362.1 - 4.9e-37 127.0 0.0 4.9e-37 127.0 0.0 1.5 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 Cyclin_C PF02984.19 GAX25362.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Cyclin, C-terminal domain GlcNAc PF11397.8 GAX25363.1 - 5.5e-58 197.1 1.0 1.1e-45 156.6 0.5 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) MatE PF01554.18 GAX25364.1 - 3.7e-20 72.2 24.6 3.4e-11 43.0 1.6 3.7 3 1 1 4 4 4 3 MatE Polysacc_synt_C PF14667.6 GAX25364.1 - 1e-10 41.9 7.8 1e-10 41.9 7.8 3.9 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF1270 PF06900.11 GAX25364.1 - 0.04 14.3 1.8 0.14 12.6 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Serpin PF00079.20 GAX25365.1 - 4.3e-56 190.8 0.0 5.1e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) LETM1 PF07766.13 GAX25366.1 - 3.2e-11 43.1 0.1 1.2e-10 41.3 0.0 1.9 1 1 1 2 2 2 1 LETM1-like protein DUF2076 PF09849.9 GAX25366.1 - 0.063 13.3 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) S-AdoMet_synt_C PF02773.16 GAX25367.1 - 4.2e-65 217.9 0.1 9.3e-65 216.8 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GAX25367.1 - 1.5e-47 160.8 0.0 2.6e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GAX25367.1 - 3.3e-43 146.4 0.3 7e-43 145.3 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DXP_synthase_N PF13292.6 GAX25369.1 - 8.5e-106 353.1 0.0 2.6e-105 351.5 0.0 1.8 2 1 1 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 GAX25369.1 - 8.8e-42 142.8 0.1 1.6e-41 141.9 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX25369.1 - 2.1e-23 82.5 0.0 6.7e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 GAX25369.1 - 1.4e-05 24.2 0.0 0.065 12.2 0.0 2.5 3 0 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 GAX25369.1 - 4.2e-05 23.4 0.1 0.0001 22.1 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 GAX25369.1 - 0.00029 19.9 0.0 0.00056 18.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component GCV_T PF01571.21 GAX25370.1 - 4.6e-83 278.5 0.0 7.2e-83 277.9 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 GAX25370.1 - 7.3e-21 73.9 0.1 1.5e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Ammonium_transp PF00909.21 GAX25371.1 - 2.7e-101 339.2 25.7 3.1e-101 339.0 25.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1240 PF06836.12 GAX25371.1 - 0.21 12.1 0.7 4.3 7.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) His_Phos_1 PF00300.22 GAX25372.1 - 1.9e-28 99.5 0.5 2.7e-28 99.0 0.1 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ADK PF00406.22 GAX25373.1 - 2.1e-42 144.8 0.0 2.7e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX25373.1 - 2.5e-31 108.9 0.0 3.4e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX25373.1 - 3.2e-11 43.9 0.0 4.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX25373.1 - 7.4e-06 26.2 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAX25373.1 - 0.036 14.3 0.0 0.24 11.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAX25373.1 - 0.039 13.6 0.1 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase WD40 PF00400.32 GAX25374.1 - 2.2e-23 82.1 18.7 1.6e-06 28.7 0.1 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25374.1 - 1.6e-17 63.6 2.6 5.9e-05 23.3 0.3 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX25374.1 - 7.2e-07 29.3 0.0 0.00049 20.0 0.0 2.8 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAX25374.1 - 3e-06 26.4 0.7 0.024 13.6 0.0 3.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAX25374.1 - 0.026 13.2 2.5 2.4 6.7 0.2 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PhyH PF05721.13 GAX25376.1 - 3.5e-06 27.4 0.0 7.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HMG_box_2 PF09011.10 GAX25376.1 - 0.0083 16.7 0.7 0.19 12.3 0.7 2.9 2 0 0 2 2 2 1 HMG-box domain BioT2 PF15368.6 GAX25376.1 - 0.23 11.4 1.8 0.49 10.3 1.8 1.5 1 0 0 1 1 1 0 Spermatogenesis family BioT2 XAP5 PF04921.14 GAX25377.1 - 2e-72 244.0 22.0 1.5e-71 241.2 22.0 2.0 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF3246 PF11596.8 GAX25377.1 - 0.028 13.8 1.4 0.039 13.4 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF98 PF01947.16 GAX25377.1 - 0.034 14.1 2.8 0.061 13.3 0.2 2.1 2 0 0 2 2 2 0 p-hydroxybenzoic acid synthase U1snRNP70_N PF12220.8 GAX25377.1 - 2.8 8.6 17.8 2.6 8.7 8.1 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ETRAMP PF09716.10 GAX25377.1 - 4.7 7.3 6.0 2.6 8.2 0.9 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Fe-ADH PF00465.19 GAX25378.1 - 2.7e-05 23.2 0.0 0.00013 20.9 0.0 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAX25378.1 - 0.0019 18.0 0.0 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase T4SS_TraI PF16932.5 GAX25378.1 - 0.077 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer ABC2_membrane PF01061.24 GAX25379.1 - 2e-33 115.6 22.1 2.8e-33 115.1 22.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX25379.1 - 2.7e-21 76.5 0.0 6e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX25379.1 - 0.00015 21.0 15.6 0.00023 20.4 15.6 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAX25379.1 - 0.00083 19.2 0.2 0.55 10.0 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAX25379.1 - 0.021 14.4 0.1 0.05 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAX25379.1 - 0.043 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 GAX25379.1 - 0.044 13.5 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 GAX25379.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SMC_N PF02463.19 GAX25379.1 - 0.12 11.7 0.0 5 6.5 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Spindle_Spc25 PF08234.12 GAX25380.1 - 1.2e-18 67.1 2.4 1.6e-18 66.7 0.5 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 GAX25380.1 - 0.00043 19.3 8.4 0.00069 18.6 8.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Prefoldin_2 PF01920.20 GAX25380.1 - 0.0099 15.8 5.0 0.0099 15.8 5.0 2.6 2 1 1 3 3 3 1 Prefoldin subunit DUF4407 PF14362.6 GAX25380.1 - 0.013 14.8 7.6 0.02 14.3 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GAX25380.1 - 0.026 14.1 3.5 0.035 13.7 3.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliD_N PF02465.18 GAX25380.1 - 0.079 13.7 2.4 1.2 9.8 0.9 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF641 PF04859.12 GAX25380.1 - 0.36 11.2 8.3 1.8 8.9 8.3 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc24 PF08286.11 GAX25380.1 - 0.47 10.7 12.5 0.11 12.7 4.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 GAX25380.1 - 0.63 10.1 16.5 2.3 8.3 16.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus P4Ha_N PF08336.11 GAX25380.1 - 0.87 9.6 9.1 0.39 10.7 3.3 2.7 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SKA2 PF16740.5 GAX25380.1 - 1.1 9.1 10.5 1.7 8.4 1.3 3.0 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 AAA_23 PF13476.6 GAX25380.1 - 1.3 9.5 8.9 2.1 8.8 8.9 1.4 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.11 GAX25380.1 - 1.4 9.4 6.4 5.3 7.5 2.0 3.4 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) DHR10 PF18595.1 GAX25380.1 - 1.6 8.8 17.6 0.43 10.7 10.9 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain ARGLU PF15346.6 GAX25380.1 - 1.7 8.5 18.7 4.4 7.2 18.7 1.6 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 DUF2730 PF10805.8 GAX25380.1 - 1.9 8.7 6.5 2.1 8.5 4.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) LOH1CR12 PF10158.9 GAX25380.1 - 2.7 8.0 6.6 0.84 9.7 0.9 2.1 1 1 1 2 2 2 0 Tumour suppressor protein End3 PF12761.7 GAX25380.1 - 2.7 8.1 13.5 0.47 10.6 8.3 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 FAM76 PF16046.5 GAX25380.1 - 3.4 6.9 8.1 5.2 6.3 8.1 1.3 1 0 0 1 1 1 0 FAM76 protein MCU PF04678.13 GAX25380.1 - 3.9 7.6 6.6 7.5 6.6 6.4 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter NAD_binding_10 PF13460.6 GAX25381.1 - 1.1e-24 87.4 1.1 1.8e-24 86.7 1.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX25381.1 - 1.4e-06 27.6 0.1 2e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GAX25381.1 - 5.2e-05 22.9 0.6 0.00012 21.8 0.2 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 GAX25381.1 - 0.0001 21.8 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX25381.1 - 0.03 13.4 0.0 0.065 12.3 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAX25381.1 - 0.038 13.1 0.4 0.09 11.9 0.4 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein SPA PF08616.10 GAX25381.1 - 0.091 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis LRR_8 PF13855.6 GAX25382.1 - 1.8e-16 59.6 31.9 8.9e-05 22.2 5.2 6.5 5 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 GAX25382.1 - 2.5e-09 37.3 27.4 0.00017 21.9 1.2 6.6 4 3 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX25382.1 - 0.0016 18.7 27.3 8 7.4 0.0 9.3 9 0 0 9 9 9 3 Leucine Rich Repeat VWA_3 PF13768.6 GAX25382.1 - 0.011 15.7 7.3 0.47 10.4 0.1 3.8 1 1 1 3 3 3 0 von Willebrand factor type A domain LRR_6 PF13516.6 GAX25382.1 - 6.1 7.2 15.6 14 6.0 0.0 7.0 8 1 0 8 8 8 0 Leucine Rich repeat Glyco_transf_64 PF09258.10 GAX25383.1 - 1.1e-38 133.0 0.0 1.5e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain SAP PF02037.27 GAX25384.1 - 2.3e-07 30.4 0.4 4.9e-07 29.4 0.4 1.6 1 0 0 1 1 1 1 SAP domain Nop53 PF07767.11 GAX25384.1 - 1.2 8.4 36.5 1.7 8.0 36.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GAX25384.1 - 2.2 6.5 23.0 2.7 6.2 23.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 GAX25384.1 - 3.5 7.5 23.5 5.2 6.9 23.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Nop14 PF04147.12 GAX25384.1 - 9.7 4.3 32.2 12 4.0 32.2 1.0 1 0 0 1 1 1 0 Nop14-like family TAF6_C PF07571.13 GAX25385.1 - 7.9e-14 51.8 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TFIID-31kDa PF02291.15 GAX25385.1 - 0.0027 17.8 0.6 0.0057 16.7 0.6 1.7 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 GAX25385.1 - 0.022 14.9 0.8 0.28 11.4 0.8 2.4 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) PDZ PF00595.24 GAX25386.1 - 3e-08 33.9 0.0 6.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX25386.1 - 5.8e-06 26.1 0.1 1.1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX25386.1 - 0.005 17.1 0.1 0.037 14.3 0.0 2.5 3 0 0 3 3 3 1 PDZ domain TMV_coat PF00721.21 GAX25386.1 - 0.086 12.7 1.6 0.23 11.3 1.6 1.7 1 0 0 1 1 1 0 Virus coat protein (TMV like) Peptidase_C1 PF00112.23 GAX25387.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Papain family cysteine protease Lipase_GDSL_2 PF13472.6 GAX25392.1 - 1.6e-26 93.8 0.0 2.7e-26 93.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX25392.1 - 5.4e-22 78.7 0.0 7.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 GAX25392.1 - 0.036 13.7 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX WD40 PF00400.32 GAX25393.1 - 2.1e-22 79.0 24.1 3.9e-06 27.5 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat PRP4 PF08799.11 GAX25393.1 - 1.2e-08 34.3 0.7 2.8e-08 33.2 0.7 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 GAX25393.1 - 4.1e-07 30.2 0.0 0.0038 17.5 0.0 4.0 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3598 PF12204.8 GAX25393.1 - 0.017 14.6 0.3 0.032 13.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) Ge1_WD40 PF16529.5 GAX25393.1 - 0.034 13.1 0.1 1.9 7.4 0.0 2.9 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2408 PF10303.9 GAX25393.1 - 0.041 14.5 4.4 0.073 13.6 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) RL10P_insert PF17777.1 GAX25393.1 - 0.083 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P eIF2A PF08662.11 GAX25393.1 - 0.11 12.3 0.1 3.3 7.5 0.0 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAX25393.1 - 0.14 10.7 0.0 0.26 9.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF5401 PF17380.2 GAX25393.1 - 2.4 6.1 11.2 3.1 5.8 11.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Clat_adaptor_s PF01217.20 GAX25395.1 - 1.8e-46 157.6 0.6 2.1e-46 157.4 0.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UCH PF00443.29 GAX25397.1 - 2.9e-67 226.9 0.0 1.2e-66 224.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX25397.1 - 7.1e-19 68.5 0.0 1.6e-12 47.7 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAX25397.1 - 2.1e-10 41.1 0.0 5.5e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Peptidase_C98 PF15499.6 GAX25397.1 - 0.0058 16.1 1.0 0.015 14.7 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase F-box PF00646.33 GAX25398.1 - 2.6e-05 24.0 2.5 2.8e-05 23.9 0.5 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAX25398.1 - 0.00011 22.0 0.2 0.00011 22.0 0.2 3.0 3 0 0 3 3 3 1 F-box-like Motile_Sperm PF00635.26 GAX25398.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain F-box_4 PF15966.5 GAX25398.1 - 1.4 8.8 5.1 1.2 9.0 0.4 2.6 2 0 0 2 2 2 0 F-box Metallophos PF00149.28 GAX25399.1 - 2.6e-38 132.6 0.1 3.4e-38 132.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAX25399.1 - 0.0031 17.9 0.1 0.0079 16.6 0.1 1.7 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 GAX25399.1 - 0.085 13.0 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Dymeclin PF09742.9 GAX25400.1 - 2.6e-64 217.8 3.0 3.7e-64 217.3 3.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Tim17 PF02466.19 GAX25401.1 - 1.2e-09 38.6 2.2 1.8e-09 38.0 1.9 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF533 PF04391.12 GAX25401.1 - 0.45 10.1 1.5 0.32 10.6 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF533) FUN14 PF04930.15 GAX25401.1 - 6.9 7.2 8.8 1.4 9.3 1.4 2.4 2 1 0 2 2 2 0 FUN14 family Lipase_GDSL PF00657.22 GAX25402.1 - 8.6e-07 29.1 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAX25402.1 - 4.1e-06 27.3 0.0 9.4e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family LBP_BPI_CETP_C PF02886.17 GAX25402.1 - 0.015 14.8 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain GLEYA PF10528.9 GAX25402.1 - 0.032 14.6 0.1 0.078 13.4 0.0 1.6 2 0 0 2 2 2 0 GLEYA domain Ferlin_C PF16165.5 GAX25402.1 - 0.059 13.3 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Ferlin C-terminus NMD3 PF04981.13 GAX25404.1 - 5.7e-56 189.7 5.4 8.2e-56 189.2 5.4 1.2 1 0 0 1 1 1 1 NMD3 family zinc_ribbon_15 PF17032.5 GAX25404.1 - 0.19 12.5 3.1 1 10.2 1.1 2.5 2 0 0 2 2 2 0 zinc-ribbon family zf-TFIIB PF13453.6 GAX25404.1 - 2.6 7.4 7.1 1.6 8.1 1.3 2.8 3 0 0 3 3 3 0 Transcription factor zinc-finger Gln-synt_C PF00120.24 GAX25405.1 - 1.5e-20 73.5 0.0 8.9e-16 57.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GAX25405.1 - 2.4e-13 49.6 0.0 4.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Mur_ligase_M PF08245.12 GAX25405.1 - 0.039 14.0 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Mur ligase middle domain Radical_SAM PF04055.21 GAX25406.1 - 2.2e-05 24.9 0.0 3.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily Lipase_3 PF01764.25 GAX25407.1 - 0.00065 19.6 0.0 0.0024 17.8 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF4347 PF14252.6 GAX25407.1 - 0.057 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) C2 PF00168.30 GAX25408.1 - 1.8e-20 73.1 0.0 4e-14 52.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain Gelsolin PF00626.22 GAX25408.1 - 0.033 14.1 0.3 0.081 12.8 0.3 1.6 1 0 0 1 1 1 0 Gelsolin repeat ArfGap PF01412.18 GAX25410.1 - 1.5e-29 102.4 0.1 2.2e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TackOD1 PF18551.1 GAX25410.1 - 0.037 13.7 1.3 0.039 13.6 0.4 1.5 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Ribosomal_L21p PF00829.21 GAX25410.1 - 0.038 14.3 0.2 0.06 13.6 0.2 1.3 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein DUF1864 PF08933.11 GAX25410.1 - 0.058 12.1 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) DUF1216 PF06746.11 GAX25411.1 - 0.0032 17.5 0.3 0.59 10.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1216) CSD PF00313.22 GAX25412.1 - 9e-19 67.1 0.1 1.5e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 GAX25412.1 - 0.017 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain YjhX_toxin PF09857.9 GAX25412.1 - 0.025 14.5 0.4 0.37 10.8 0.0 2.6 3 1 1 4 4 4 0 Putative toxin of bacterial toxin-antitoxin pair Peptidase_C1 PF00112.23 GAX25413.1 - 9.6e-51 172.9 3.0 1.8e-50 172.1 3.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAX25413.1 - 0.00017 20.5 0.3 0.00088 18.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Inhibitor_I29 PF08246.12 GAX25413.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) U3_snoRNA_assoc PF08297.11 GAX25413.1 - 0.2 12.4 0.0 0.34 11.6 0.0 1.3 1 0 0 1 1 1 0 U3 snoRNA associated ORC3_N PF07034.11 GAX25414.1 - 0.00017 20.8 0.2 0.00042 19.5 0.0 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Pkinase PF00069.25 GAX25415.1 - 4.4e-54 183.6 0.2 1.5e-53 181.9 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX25415.1 - 6.7e-25 87.8 0.1 9.8e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX25415.1 - 0.0013 18.8 0.1 0.0025 17.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX25415.1 - 0.0013 18.4 0.0 0.0059 16.2 0.0 1.9 1 1 0 2 2 2 1 Choline/ethanolamine kinase SelR PF01641.18 GAX25415.1 - 0.065 13.3 0.1 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 SelR domain ABC1 PF03109.16 GAX25415.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC1 family E1-E2_ATPase PF00122.20 GAX25416.1 - 8.7e-20 71.0 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 GAX25416.1 - 0.00064 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Peptidase_S77 PF03420.13 GAX25416.1 - 0.066 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Prohead core protein serine protease FliMN_C PF01052.20 GAX25416.1 - 0.084 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term RNA_pol_A_bac PF01000.26 GAX25417.1 - 7.3e-23 81.1 0.1 2.2e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAX25417.1 - 4.2e-21 74.2 0.0 5.7e-21 73.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain OB_RNB PF08206.11 GAX25417.1 - 0.038 13.7 0.1 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Ribonuclease B OB domain RNA_pol_L_2 PF13656.6 GAX25417.1 - 0.056 13.2 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Pro_isomerase PF00160.21 GAX25418.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pannexin_like PF12534.8 GAX25418.1 - 0.12 11.4 3.9 0.19 10.8 3.9 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Atg14 PF10186.9 GAX25418.1 - 0.45 9.5 9.8 0.82 8.7 9.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribo_biogen_C PF04034.13 GAX25419.1 - 3.5e-51 172.2 0.0 4.8e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 GAX25419.1 - 1.2e-07 31.5 0.2 2.1e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Rhodanese_C PF12368.8 GAX25420.1 - 7.1e-13 48.7 8.2 7.1e-13 48.7 8.2 1.9 2 0 0 2 2 2 1 Rhodanase C-terminal UPF0176_N PF17773.1 GAX25420.1 - 3.1e-06 27.5 0.0 9.5e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain zf-CCCH_2 PF14608.6 GAX25420.1 - 0.00027 21.3 3.4 0.00071 19.9 3.4 1.8 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Rhodanese PF00581.20 GAX25420.1 - 0.0012 19.4 0.0 0.0028 18.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF4570 PF15134.6 GAX25420.1 - 0.057 13.4 0.7 0.11 12.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF2430 PF10353.9 GAX25420.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) MAS20 PF02064.15 GAX25420.1 - 0.58 10.3 3.6 8.8 6.4 2.1 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor FYVE PF01363.21 GAX25420.1 - 0.78 9.9 10.2 2.3 8.4 10.2 1.9 1 1 0 1 1 1 0 FYVE zinc finger RRM_1 PF00076.22 GAX25421.1 - 3.9e-27 93.9 0.0 3.8e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX25421.1 - 7.4e-06 26.0 0.0 0.2 11.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 GAX25421.1 - 0.0014 18.9 0.5 0.0014 18.9 0.5 2.5 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter DUF3464 PF11947.8 GAX25421.1 - 0.22 11.3 1.2 0.43 10.3 1.2 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Glycoprotein_G PF00802.19 GAX25421.1 - 0.23 10.8 2.3 0.47 9.8 2.3 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Presenilin PF01080.17 GAX25421.1 - 0.95 8.2 2.6 0.99 8.1 2.6 1.2 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 GAX25421.1 - 1.1 9.4 7.7 0.52 10.5 5.2 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Kinesin PF00225.23 GAX25422.1 - 4.2e-53 180.4 0.8 1.4e-51 175.4 0.0 3.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAX25422.1 - 5.2e-19 68.7 0.0 1.3e-17 64.1 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding Med30 PF11315.8 GAX25422.1 - 6 7.1 10.7 5.6 7.2 1.8 3.2 2 0 0 2 2 2 0 Mediator complex subunit 30 DUF2388 PF09498.10 GAX25423.1 - 3.4e-10 39.8 21.1 64 3.6 0.0 24.5 33 0 0 33 33 33 0 Protein of unknown function (DUF2388) KIX_2 PF16987.5 GAX25423.1 - 0.0002 21.3 0.1 78 3.4 0.0 9.8 10 0 0 10 10 10 0 KIX domain hnRNP_Q_AcD PF18360.1 GAX25423.1 - 0.00042 20.2 0.1 51 3.9 0.0 10.2 11 0 0 11 11 11 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Pox_A3L PF05288.11 GAX25423.1 - 0.0035 17.3 0.0 1.4e+02 2.5 0.0 7.6 8 0 0 8 8 8 0 Poxvirus A3L Protein DnaB_bind PF10410.9 GAX25423.1 - 0.0044 17.2 0.2 85 3.5 0.0 7.1 7 0 0 7 7 7 0 DnaB-helicase binding domain of primase DUF4620 PF15399.6 GAX25423.1 - 0.0086 16.4 9.3 16 5.9 0.0 9.9 11 0 0 11 11 11 1 Domain of unknown function (DUF4620) Maelstrom PF13017.6 GAX25423.1 - 0.019 14.6 0.1 22 4.6 0.0 6.2 6 1 1 7 7 7 0 piRNA pathway germ-plasm component Slx4 PF09494.10 GAX25423.1 - 0.057 13.4 12.7 5.6e+02 0.6 0.0 14.4 19 0 0 19 19 19 0 Slx4 endonuclease DUF3006 PF11213.8 GAX25423.1 - 0.077 13.2 1.0 0.36 11.1 1.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) NUDIX PF00293.28 GAX25424.1 - 3.5e-11 43.2 0.0 1.2e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Hydrolase_like PF13242.6 GAX25424.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX25424.1 - 0.029 14.7 0.0 0.094 13.0 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 GAX25425.1 - 8.7e-26 90.6 0.1 1.6e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 GAX25425.1 - 0.069 12.9 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin family TAP42 PF04177.12 GAX25426.1 - 2.9e-50 171.2 11.3 3.5e-50 170.9 11.3 1.0 1 0 0 1 1 1 1 TAP42-like family DUF3509 PF12021.8 GAX25426.1 - 2.8 7.7 6.7 1.9 8.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) Pkinase PF00069.25 GAX25427.1 - 4.4e-64 216.4 0.2 5.2e-64 216.2 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX25427.1 - 6.6e-18 64.9 0.0 9.4e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX25427.1 - 3.8e-06 27.0 0.0 1.4e-05 25.2 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX25427.1 - 0.021 13.6 0.1 0.072 11.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 GAX25427.1 - 0.023 14.0 0.2 0.039 13.3 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAX25427.1 - 0.027 14.1 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.8 GAX25427.1 - 0.094 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain DUF2459 PF09601.10 GAX25427.1 - 0.098 12.5 0.0 0.93 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) FAD_binding_3 PF01494.19 GAX25428.1 - 2e-17 63.5 0.0 1.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 GAX25428.1 - 0.00068 20.1 0.6 0.086 13.4 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX25428.1 - 0.0008 19.1 0.2 0.0027 17.4 0.2 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX25428.1 - 0.00082 19.6 0.1 0.0018 18.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 GAX25428.1 - 0.014 14.7 0.7 0.052 12.8 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 GAX25428.1 - 0.024 13.9 0.1 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX25428.1 - 0.059 12.4 0.0 4 6.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short_C2 PF13561.6 GAX25429.1 - 1.4e-28 100.0 0.1 1.8e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX25429.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.6 GAX25430.1 - 1.9e-28 99.6 0.1 2.4e-28 99.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX25430.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase MSP1b PF03429.13 GAX25430.1 - 0.051 11.7 0.0 0.065 11.3 0.0 1.3 1 0 0 1 1 1 0 Major surface protein 1B Chorismate_synt PF01264.21 GAX25432.1 - 5.3e-136 452.6 0.7 6.2e-136 452.4 0.7 1.0 1 0 0 1 1 1 1 Chorismate synthase ThiF PF00899.21 GAX25432.1 - 0.03 13.7 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 ThiF family DUF1573 PF07610.11 GAX25432.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) Peptidase_C1 PF00112.23 GAX25433.1 - 2.3e-36 125.9 1.5 1.5e-29 103.6 0.8 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAX25433.1 - 0.021 13.6 0.8 0.096 11.4 0.2 1.9 2 0 0 2 2 2 0 Peptidase C1-like family TPR_8 PF13181.6 GAX25434.1 - 0.035 14.3 0.1 1.6 9.2 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3603 PF12227.8 GAX25434.1 - 0.039 13.3 0.7 4.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3603) TPR_19 PF14559.6 GAX25434.1 - 0.042 14.4 0.5 48 4.6 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Rhomboid PF01694.22 GAX25435.1 - 1.9e-20 73.4 15.6 1.9e-20 73.4 15.6 1.8 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 GAX25435.1 - 0.0017 18.9 1.3 0.0052 17.3 0.2 2.4 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF1275 PF06912.11 GAX25435.1 - 0.073 13.0 8.8 0.66 9.9 8.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) ZYG-11_interact PF05884.12 GAX25435.1 - 0.11 11.9 7.2 0.19 11.1 4.8 2.1 1 1 1 2 2 2 0 Interactor of ZYG-11 DinB PF05163.12 GAX25435.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 DinB family YesK PF14150.6 GAX25435.1 - 0.89 9.8 6.2 1.1 9.5 0.1 2.6 2 1 0 2 2 2 0 YesK-like protein DUF4149 PF13664.6 GAX25435.1 - 2.2 8.7 7.5 0.62 10.4 2.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) TPMT PF05724.11 GAX25436.1 - 2.2e-41 142.0 0.0 2.7e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 GAX25436.1 - 0.00018 22.1 0.0 0.00035 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX25436.1 - 0.00092 19.1 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX25436.1 - 0.0019 18.9 0.0 0.0055 17.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX25436.1 - 0.086 13.6 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TPR_19 PF14559.6 GAX25437.1 - 0.024 15.1 2.1 2.8 8.5 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX25437.1 - 0.15 11.8 1.1 5.8 6.7 0.1 2.9 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 GAX25437.1 - 0.96 10.4 5.0 44 5.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 GAX25438.1 - 5.3e-15 55.8 0.1 8.7e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding tRNA-synt_1e PF01406.19 GAX25439.1 - 7.5e-96 321.0 0.0 1.1e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAX25439.1 - 2.1e-08 33.3 0.0 0.0002 20.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DUF2491 PF10679.9 GAX25439.1 - 0.017 14.3 0.0 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2491) tRNA-synt_1 PF00133.22 GAX25439.1 - 0.019 13.3 0.0 0.47 8.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) Cupin_2 PF07883.11 GAX25441.1 - 3.9e-07 29.7 0.0 6.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GAX25441.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain PPR_2 PF13041.6 GAX25442.1 - 3.4e-11 43.2 0.7 6e-08 32.8 0.0 3.6 4 0 0 4 4 4 2 PPR repeat family Methyltransf_4 PF02390.17 GAX25442.1 - 1.3e-08 34.5 0.4 4.7e-06 26.2 0.0 3.1 4 0 0 4 4 4 2 Putative methyltransferase PPR PF01535.20 GAX25442.1 - 1.9e-08 34.0 8.3 0.0027 17.8 0.1 5.1 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.7 GAX25442.1 - 1.5e-07 31.0 5.1 0.22 11.2 0.0 4.3 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 GAX25442.1 - 3.5e-05 23.3 4.5 0.0025 17.2 1.2 2.7 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GAX25442.1 - 0.00059 19.9 0.0 0.0041 17.2 0.0 2.2 1 1 1 2 2 2 1 Pentatricopeptide repeat domain TPR_19 PF14559.6 GAX25442.1 - 0.007 16.8 1.5 5.9 7.5 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX25442.1 - 0.011 16.5 0.1 36 5.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX25442.1 - 0.074 13.3 0.8 2.2 8.6 0.3 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 GAX25442.1 - 0.12 12.8 0.9 2.3 8.6 0.9 2.6 1 1 0 1 1 1 0 Bacterial transcriptional activator domain NMO PF03060.15 GAX25443.1 - 5.8e-57 193.5 5.4 4.5e-54 184.0 5.4 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAX25443.1 - 3.3e-14 52.6 2.4 1.1e-13 50.9 2.4 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAX25443.1 - 6.7e-12 45.1 3.9 9.5e-12 44.6 3.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 GAX25443.1 - 0.00092 18.6 6.7 0.0036 16.7 6.8 1.8 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 GAX25443.1 - 0.076 12.1 5.1 0.18 10.9 0.2 2.5 3 0 0 3 3 3 0 Conserved region in glutamate synthase His_biosynth PF00977.21 GAX25443.1 - 0.087 12.3 0.3 0.28 10.6 0.3 1.7 1 1 1 2 2 2 0 Histidine biosynthesis protein DUF3523 PF12037.8 GAX25444.1 - 7.6e-86 287.8 27.0 1.3e-85 287.1 27.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 GAX25444.1 - 3.3e-22 79.3 0.0 8.7e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX25444.1 - 3e-05 23.8 0.0 0.0001 22.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX25444.1 - 0.0003 20.8 4.4 0.0044 17.0 0.2 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX25444.1 - 0.00059 20.2 0.0 0.00059 20.2 0.0 3.6 2 2 1 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 GAX25444.1 - 0.001 19.2 0.0 0.001 19.2 0.0 3.9 4 1 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 GAX25444.1 - 0.0015 18.0 0.0 0.0044 16.4 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAX25444.1 - 0.0019 18.7 2.7 0.02 15.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX25444.1 - 0.0022 18.3 5.5 0.0054 17.0 0.0 3.3 2 2 0 3 3 3 1 AAA domain NACHT PF05729.12 GAX25444.1 - 0.0083 16.1 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 GAX25444.1 - 0.0089 16.0 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Borrelia_P83 PF05262.11 GAX25444.1 - 0.0095 14.5 18.2 0.013 14.0 18.2 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein AAA_3 PF07726.11 GAX25444.1 - 0.012 15.4 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 GAX25444.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 GAX25444.1 - 0.061 13.1 0.0 0.061 13.1 0.0 2.9 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 GAX25444.1 - 0.077 12.7 1.7 0.11 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAX25444.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CDK5_activator PF03261.15 GAX25444.1 - 0.31 10.6 9.8 0.49 9.9 9.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein GHMP_kinases_N PF00288.26 GAX25445.1 - 9.6e-14 51.4 3.0 2.3e-13 50.1 3.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Rhomboid PF01694.22 GAX25447.1 - 5e-35 120.7 7.4 6.6e-35 120.3 7.4 1.2 1 0 0 1 1 1 1 Rhomboid family Coatomer_E PF04733.14 GAX25448.1 - 5.3e-47 160.6 1.2 6.1e-47 160.4 1.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 GAX25448.1 - 3.9e-05 23.4 1.0 0.0033 17.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX25448.1 - 0.00097 19.6 11.9 0.68 10.5 0.0 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25448.1 - 0.0036 17.2 3.9 0.025 14.6 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX25448.1 - 0.01 16.6 9.8 0.25 12.3 0.0 4.7 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25448.1 - 0.028 15.1 2.3 0.19 12.4 0.0 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX25448.1 - 0.034 14.0 0.7 0.38 10.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25448.1 - 0.056 13.3 3.5 0.49 10.3 0.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX25448.1 - 0.16 12.7 4.9 0.56 11.0 0.0 4.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25448.1 - 0.19 12.0 5.8 1.8 9.0 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX25448.1 - 0.35 11.6 2.4 53 4.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX25448.1 - 1.3 9.6 5.3 4.7 7.8 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro81C PF17652.1 GAX25449.1 - 2.3e-67 227.7 1.1 3.4e-67 227.2 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAX25449.1 - 4.2e-31 108.3 0.0 1.6e-19 70.2 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain SLAC1 PF03595.17 GAX25449.1 - 0.011 15.1 0.2 0.018 14.3 0.2 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel Arginase PF00491.21 GAX25450.1 - 1.6e-76 257.5 0.0 2e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family Fuseless PF15993.5 GAX25451.1 - 1.1e-13 51.1 1.2 3.1e-13 49.6 1.2 1.7 1 1 0 1 1 1 1 Fuseless EamA PF00892.20 GAX25452.1 - 2e-05 24.8 13.8 2.7e-05 24.3 13.8 1.2 1 0 0 1 1 1 1 EamA-like transporter family SelR PF01641.18 GAX25453.1 - 0.0045 17.1 0.1 0.051 13.7 0.1 2.5 1 1 0 1 1 1 1 SelR domain tRNA-synt_1 PF00133.22 GAX25454.1 - 6.7e-205 681.9 0.0 7.8e-204 678.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAX25454.1 - 6.9e-37 126.8 0.0 1.2e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAX25454.1 - 7e-24 84.3 0.0 1.2e-08 34.1 0.0 3.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 GAX25454.1 - 2.6e-18 66.0 6.5 2.6e-18 66.0 6.5 1.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 GAX25454.1 - 4.2e-13 49.2 0.0 6e-10 38.9 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAX25454.1 - 0.026 13.9 0.0 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GAX25454.1 - 0.054 12.4 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) ABC_tran_CTD PF16326.5 GAX25454.1 - 0.13 12.5 3.3 0.59 10.4 3.3 2.1 1 0 0 1 1 1 0 ABC transporter C-terminal domain tRNA-synt_1b PF00579.25 GAX25454.1 - 0.2 11.0 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF4140 PF13600.6 GAX25454.1 - 9.5 6.7 6.4 25 5.4 0.8 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PI3_PI4_kinase PF00454.27 GAX25455.1 - 2.9e-24 86.3 0.0 6.9e-23 81.7 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PX PF00787.24 GAX25455.1 - 0.045 13.7 0.2 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 PX domain DUF1943 PF09172.11 GAX25456.1 - 0.082 12.1 0.4 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) DUF4611 PF15387.6 GAX25456.1 - 2.8 8.2 9.3 0.21 11.9 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Methyltransf_16 PF10294.9 GAX25457.1 - 1.7e-18 67.0 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX25457.1 - 0.0036 16.9 0.0 0.0066 16.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX25457.1 - 0.0054 17.4 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX25457.1 - 0.0077 16.9 0.0 0.016 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX25457.1 - 0.041 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX25457.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NUDIX PF00293.28 GAX25458.1 - 1.5e-11 44.4 0.1 3.6e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Seipin PF06775.14 GAX25459.1 - 1.1e-38 133.4 0.8 1.3e-38 133.1 0.8 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Saf_2TM PF18303.1 GAX25459.1 - 0.13 11.8 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain 7tm_3 PF00003.22 GAX25461.1 - 1e-17 64.7 11.0 1.3e-17 64.3 8.2 2.1 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF3493 PF11998.8 GAX25461.1 - 0.1 12.8 2.4 1.7 8.9 0.3 2.9 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 CDC48_2 PF02933.17 GAX25461.1 - 0.27 11.0 1.1 6.2 6.7 0.2 2.4 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Ost5 PF05251.12 GAX25461.1 - 2 8.7 7.7 5.6 7.3 2.3 3.3 2 1 1 3 3 3 0 Oligosaccharyltransferase subunit 5 Complex1_LYR PF05347.15 GAX25462.1 - 4e-15 55.6 0.5 5.7e-15 55.1 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 GAX25462.1 - 5.9e-05 23.6 0.0 7.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ETC_C1_NDUFA5 PF04716.14 GAX25462.1 - 0.0014 18.4 0.1 0.0027 17.5 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Complex1_LYR_2 PF13233.6 GAX25462.1 - 0.0087 16.8 1.6 0.01 16.6 1.6 1.3 1 1 0 1 1 1 1 Complex1_LYR-like 60KD_IMP PF02096.20 GAX25463.1 - 1.1e-52 178.2 0.8 1.6e-52 177.8 0.8 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2062 PF09835.9 GAX25463.1 - 0.094 12.6 3.2 0.22 11.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) LAP1C PF05609.12 GAX25463.1 - 1.3 8.0 7.5 0.28 10.2 0.1 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Sigma70_r2 PF04542.14 GAX25464.1 - 4.7e-13 48.7 0.0 9.4e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 GAX25464.1 - 1.9e-12 47.1 7.4 4.9e-06 26.6 1.4 3.5 3 0 0 3 3 3 3 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 GAX25464.1 - 0.0097 15.6 0.2 0.054 13.2 0.0 2.4 2 1 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 GAX25464.1 - 0.016 14.7 0.3 0.088 12.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_29 PF13551.6 GAX25464.1 - 0.12 12.5 0.0 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 GAX25464.1 - 0.14 11.6 2.2 0.49 9.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 AAA_lid_9 PF17871.1 GAX25464.1 - 0.73 9.8 4.9 0.29 11.1 0.2 2.6 2 0 0 2 2 2 0 AAA lid domain Collectrin PF16959.5 GAX25465.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Renal amino acid transporter EamA PF00892.20 GAX25465.1 - 0.035 14.3 0.8 0.035 14.3 0.8 2.2 2 1 0 2 2 2 0 EamA-like transporter family SNX17_FERM_C PF18116.1 GAX25466.1 - 0.14 12.3 0.1 0.43 10.7 0.1 1.8 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain DUF285 PF03382.14 GAX25467.1 - 1.6e-54 182.8 16.2 9.9e-29 99.6 6.3 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 MMR_HSR1 PF01926.23 GAX25468.1 - 1.9e-17 63.4 0.4 3.8e-17 62.4 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX25468.1 - 1.4e-08 34.5 0.4 9.7e-08 31.7 0.0 2.4 2 1 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX25468.1 - 5.9e-06 26.4 1.6 0.027 14.5 0.2 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 GAX25468.1 - 4.9e-05 23.0 1.0 0.12 11.9 0.1 3.5 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Arf PF00025.21 GAX25468.1 - 0.00015 21.3 0.0 0.00037 20.0 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAX25468.1 - 0.0011 18.5 0.2 0.0023 17.4 0.1 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAX25468.1 - 0.0011 18.9 0.1 0.037 13.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase KH_2 PF07650.17 GAX25468.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 KH domain AIG1 PF04548.16 GAX25468.1 - 0.022 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 GAX25468.1 - 0.033 13.8 0.3 0.17 11.4 0.1 2.0 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF285 PF03382.14 GAX25469.1 - 2.8e-30 104.6 8.0 4.8e-30 103.8 8.0 1.4 1 1 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 Med7 PF05983.11 GAX25471.1 - 1.6e-11 44.6 23.5 9.8e-10 38.8 23.5 2.4 1 1 0 1 1 1 1 MED7 protein Occludin_ELL PF07303.13 GAX25471.1 - 0.19 12.5 3.8 0.31 11.8 3.8 1.4 1 0 0 1 1 1 0 Occludin homology domain DUF4131 PF13567.6 GAX25472.1 - 0.14 11.8 0.2 0.31 10.7 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) GYF PF02213.16 GAX25473.1 - 6.7e-10 38.5 1.2 1e-09 37.9 0.1 1.9 2 0 0 2 2 2 1 GYF domain Use1 PF09753.9 GAX25473.1 - 0.95 9.1 5.7 0.51 10.0 0.2 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 Methyltransf_23 PF13489.6 GAX25474.1 - 0.035 13.9 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAX25474.1 - 0.074 13.8 0.1 0.28 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 GAX25474.1 - 0.19 11.4 0.0 0.91 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HMG_box PF00505.19 GAX25475.1 - 1.3e-32 112.0 12.1 7.6e-23 80.7 3.2 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX25475.1 - 1.9e-16 60.4 12.9 1.1e-08 35.5 4.2 2.5 2 0 0 2 2 2 2 HMG-box domain FAM195 PF14799.6 GAX25475.1 - 0.67 10.3 5.7 0.18 12.2 0.7 2.2 1 1 0 2 2 2 0 FAM195 family Ccdc124 PF06244.12 GAX25475.1 - 5.1 7.7 9.4 0.23 12.0 2.2 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 Sec63 PF02889.16 GAX25476.1 - 3.5e-148 491.7 2.6 8.7e-79 264.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAX25476.1 - 3.5e-41 140.9 0.0 4.8e-25 88.3 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GAX25476.1 - 2.9e-25 88.6 1.3 2.9e-25 88.6 1.3 3.3 4 0 0 4 4 4 1 N-terminal helicase PWI domain ResIII PF04851.15 GAX25476.1 - 5e-20 72.2 0.0 6.4e-12 45.8 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAX25476.1 - 1.2e-07 32.0 0.0 4.3e-06 27.0 0.0 3.3 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAX25476.1 - 1.5e-05 24.8 0.0 0.27 10.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 GAX25476.1 - 0.00024 21.4 0.9 0.072 13.4 0.0 3.6 3 1 0 3 3 3 1 AAA domain T2SSE PF00437.20 GAX25476.1 - 0.047 12.7 0.0 2.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 GAX25476.1 - 0.068 12.9 0.0 1.7 8.3 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 GAX25476.1 - 0.19 11.5 2.5 2.3 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain BUD22 PF09073.10 GAX25476.1 - 0.64 9.3 10.8 1.4 8.2 10.8 1.5 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GAX25476.1 - 2.8 7.3 19.4 5.6 6.3 19.4 1.5 1 0 0 1 1 1 0 SDA1 DUF285 PF03382.14 GAX25477.1 - 7.1e-63 209.8 23.6 1.3e-32 112.1 4.4 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 2OG-FeII_Oxy_2 PF13532.6 GAX25478.1 - 2e-07 31.4 0.0 2.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CTD_bind PF04818.13 GAX25479.1 - 0.0029 18.4 0.9 0.01 16.7 0.9 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. AAA_22 PF13401.6 GAX25480.1 - 0.033 14.4 0.0 0.074 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAX25480.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pyrophosphatase PF00719.19 GAX25481.1 - 2.1e-47 160.9 0.1 2.9e-47 160.4 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec66 PF09802.9 GAX25482.1 - 4.9e-12 45.8 10.3 6.1e-12 45.5 10.0 1.4 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 Gram_pos_anchor PF00746.21 GAX25482.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Stn1 PF10451.9 GAX25482.1 - 0.86 8.5 5.7 1.3 7.9 5.7 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 CRT10 PF08728.10 GAX25482.1 - 3.7 5.6 5.8 4.8 5.2 5.8 1.1 1 0 0 1 1 1 0 CRT10 RAB3GAP2_N PF14655.6 GAX25483.1 - 6.8e-30 104.7 0.0 1.1e-29 104.0 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 GAX25483.1 - 1.8e-07 29.8 2.6 0.0027 16.0 0.0 3.1 3 0 0 3 3 3 3 Rab3 GTPase-activating protein regulatory subunit C-terminus AP4E_app_platf PF14807.6 GAX25483.1 - 0.17 12.3 0.4 0.47 10.8 0.4 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF726 PF05277.12 GAX25484.1 - 4.1e-60 203.5 6.6 3.9e-33 114.8 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF726) Strep_SA_rep PF06696.11 GAX25484.1 - 0.059 13.4 0.4 0.16 12.0 0.4 1.8 1 0 0 1 1 1 0 Streptococcal surface antigen repeat VirJ PF06057.11 GAX25484.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.7 GAX25484.1 - 0.15 12.6 0.1 0.44 11.1 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4781 PF16013.5 GAX25484.1 - 0.29 9.9 1.5 0.55 9.0 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Yippee-Mis18 PF03226.14 GAX25485.1 - 5.2e-13 49.1 0.5 9.9e-13 48.2 0.5 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 GAX25485.1 - 0.023 14.9 0.5 0.043 14.1 0.5 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I zf_UBZ PF18439.1 GAX25485.1 - 0.11 12.1 1.4 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Roughex PF06020.11 GAX25486.1 - 0.0055 15.9 0.5 0.0055 15.9 0.5 1.6 2 0 0 2 2 2 1 Drosophila roughex protein Caskin-Pro-rich PF16907.5 GAX25486.1 - 1.4 9.5 7.7 18 5.9 7.7 2.3 1 1 0 1 1 1 0 Proline rich region of Caskin proteins Vta1 PF04652.16 GAX25487.1 - 5.2e-37 127.0 0.6 5.2e-37 127.0 0.6 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 GAX25487.1 - 0.0062 16.2 1.8 0.0062 16.2 1.8 1.7 2 0 0 2 2 2 1 Vta1 C-terminal domain DUF3090 PF11290.8 GAX25488.1 - 0.92 9.3 4.0 0.39 10.5 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3090) ArfGap PF01412.18 GAX25489.1 - 8.6e-32 109.7 0.1 1.3e-31 109.1 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf VitD-bind_III PF09164.10 GAX25489.1 - 0.089 12.8 0.2 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF2937 PF11157.8 GAX25489.1 - 0.17 11.6 0.4 0.28 10.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) 2-oxoacid_dh PF00198.23 GAX25490.1 - 4.6e-71 239.0 0.0 6.5e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAX25490.1 - 5.4e-15 55.0 0.1 1.6e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 GAX25490.1 - 6.5e-12 45.6 1.0 1.5e-11 44.4 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain SAP130_C PF16014.5 GAX25490.1 - 3.4 6.7 9.7 6.6 5.7 9.7 1.5 1 1 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus MgtE PF01769.16 GAX25491.1 - 2.5e-17 63.4 6.0 4.1e-17 62.7 6.0 1.3 1 0 0 1 1 1 1 Divalent cation transporter Rgp1 PF08737.10 GAX25491.1 - 1.9 7.6 5.5 11 5.1 0.0 2.0 1 1 1 2 2 2 0 Rgp1 TPR_2 PF07719.17 GAX25492.1 - 1.4e-25 87.3 18.2 0.00029 20.7 0.0 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25492.1 - 1.3e-18 65.5 18.5 0.00061 19.8 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAX25492.1 - 7.5e-18 63.9 4.9 2.1e-05 24.1 0.0 6.6 5 1 1 6 6 6 3 TPR repeat TPR_19 PF14559.6 GAX25492.1 - 1.7e-16 60.5 25.3 1e-07 32.4 4.3 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAX25492.1 - 3.4e-16 58.4 10.2 0.023 15.0 0.2 7.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25492.1 - 9.4e-13 47.4 27.5 0.0058 16.4 0.0 9.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25492.1 - 1.3e-12 48.1 19.5 0.00034 21.2 1.6 6.1 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAX25492.1 - 1.9e-12 46.9 22.5 0.025 15.4 0.5 8.7 6 1 4 10 10 8 5 Tetratricopeptide repeat TPR_21 PF09976.9 GAX25492.1 - 4.7e-10 39.5 3.8 4.7e-10 39.5 3.8 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GAX25492.1 - 3.1e-05 24.0 11.4 0.016 15.4 1.3 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 GAX25492.1 - 0.00014 20.9 5.9 0.082 11.8 0.0 3.5 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 GAX25492.1 - 0.0019 18.7 16.6 4.5 8.1 0.2 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25492.1 - 0.0019 18.1 3.8 31 4.9 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GAX25492.1 - 0.0025 17.3 0.9 0.0068 15.9 0.1 2.1 2 1 0 2 2 2 1 Coatomer epsilon subunit TPR_12 PF13424.6 GAX25492.1 - 0.0027 18.0 22.3 1.4 9.3 0.3 7.2 4 3 2 7 7 7 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GAX25492.1 - 0.053 13.2 1.9 0.31 10.7 2.0 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) HemY_N PF07219.13 GAX25492.1 - 0.077 13.2 2.0 15 5.8 0.0 3.7 2 1 2 4 4 4 0 HemY protein N-terminus MIT PF04212.18 GAX25492.1 - 0.078 13.0 10.6 1.4 9.0 0.1 4.5 5 0 0 5 5 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 GAX25492.1 - 0.12 13.1 0.5 13 6.7 0.2 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX25492.1 - 8.8 6.3 14.0 43 4.2 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat PTR2 PF00854.21 GAX25493.1 - 1.5e-40 139.3 15.6 1.4e-21 76.8 2.8 2.3 2 0 0 2 2 2 2 POT family DUF4490 PF14892.6 GAX25493.1 - 0.012 15.6 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) HSF_DNA-bind PF00447.17 GAX25494.1 - 5.2e-17 62.2 0.9 1.1e-16 61.2 0.0 1.9 3 0 0 3 3 3 1 HSF-type DNA-binding Ets PF00178.22 GAX25494.1 - 0.0087 16.5 1.5 0.017 15.6 0.0 2.1 2 0 0 2 2 2 1 Ets-domain Ribosomal_S15 PF00312.22 GAX25495.1 - 8.5e-31 106.0 0.7 1.4e-30 105.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 polyprenyl_synt PF00348.17 GAX25496.1 - 1.3e-57 194.8 0.0 1.8e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Proteasome PF00227.26 GAX25497.1 - 2.6e-58 196.6 0.1 3.5e-58 196.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX25497.1 - 7.6e-13 47.9 0.0 1.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DEAD PF00270.29 GAX25498.1 - 4.8e-33 114.4 0.1 1.9e-32 112.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX25498.1 - 3.7e-27 94.9 0.0 8.2e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX25498.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAX25498.1 - 0.0045 17.3 0.6 0.0086 16.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain ATP-grasp_6 PF18419.1 GAX25498.1 - 0.0099 15.5 0.1 0.081 12.6 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp-like domain tRNA-synt_1b PF00579.25 GAX25498.1 - 0.035 13.4 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AAA_30 PF13604.6 GAX25498.1 - 0.076 12.7 0.3 0.34 10.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX25498.1 - 0.14 12.4 0.2 2.5 8.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain His_Phos_1 PF00300.22 GAX25499.1 - 1.2e-19 70.7 0.3 3.6e-19 69.2 0.0 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) OST-HTH PF12872.7 GAX25501.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain FumaraseC_C PF10415.9 GAX25501.1 - 0.088 13.2 0.2 0.36 11.3 0.1 1.9 2 0 0 2 2 2 0 Fumarase C C-terminus RVT_2 PF07727.14 GAX25502.1 - 7.9e-39 133.7 0.2 1.5e-38 132.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX25502.1 - 1.1e-12 48.2 0.0 2.8e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GAX25502.1 - 3e-11 42.9 13.8 6.5e-07 29.1 1.6 2.5 2 0 0 2 2 2 2 Zinc knuckle gag_pre-integrs PF13976.6 GAX25502.1 - 1.4e-05 24.9 0.0 1.4e-05 24.9 0.0 1.9 2 0 0 2 2 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 GAX25502.1 - 1.4e-05 24.8 0.1 4.6e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 GAX25502.1 - 0.0002 21.1 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_2 PF13696.6 GAX25502.1 - 0.018 14.8 0.4 0.018 14.8 0.4 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GAX25502.1 - 0.038 14.0 12.8 0.28 11.2 1.0 2.8 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GAX25502.1 - 0.1 12.3 6.6 2 8.2 0.6 2.8 2 0 0 2 2 2 0 Zinc knuckle HypA PF01155.19 GAX25502.1 - 3.3 7.8 8.6 33 4.6 4.8 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SAP PF02037.27 GAX25502.1 - 3.5 7.5 5.5 3.6 7.5 0.3 2.9 3 0 0 3 3 3 0 SAP domain zf-CCHC_5 PF14787.6 GAX25502.1 - 4.2 7.2 13.7 9.1 6.1 1.1 2.4 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger RRM_1 PF00076.22 GAX25505.1 - 3.2e-09 36.5 0.0 6.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 GAX25505.1 - 5.1e-07 30.4 0.4 1.5e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 GAX25505.1 - 7.8e-05 22.6 3.7 7.8e-05 22.6 3.7 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 GAX25505.1 - 8e-05 22.4 3.7 8e-05 22.4 3.7 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) REC114-like PF15165.6 GAX25505.1 - 0.0012 18.6 0.5 0.0012 18.6 0.5 1.9 2 0 0 2 2 2 1 Meiotic recombination protein REC114-like zf-CCCH_3 PF15663.5 GAX25505.1 - 0.02 15.1 0.3 0.069 13.4 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger containing family FYVE PF01363.21 GAX25505.1 - 0.041 14.0 1.5 0.066 13.3 0.2 2.0 2 0 0 2 2 2 0 FYVE zinc finger Nup35_RRM_2 PF14605.6 GAX25505.1 - 0.11 12.6 0.1 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 GAX25505.1 - 0.47 10.3 5.7 0.18 11.6 2.5 2.0 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAX25505.1 - 1.9 9.1 6.4 0.33 11.5 2.0 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger HMG_box PF00505.19 GAX25507.1 - 3.2e-06 27.5 6.4 2.2e-05 24.8 6.4 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box eIF-3c_N PF05470.12 GAX25507.1 - 0.0032 15.9 0.4 0.0038 15.6 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HMG_box_2 PF09011.10 GAX25507.1 - 0.019 15.5 6.8 0.047 14.3 6.8 1.8 1 1 0 1 1 1 0 HMG-box domain DUF3987 PF13148.6 GAX25507.1 - 0.052 12.6 1.3 0.076 12.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2924 PF11149.8 GAX25507.1 - 0.49 10.8 5.8 1 9.7 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) TauE PF01925.19 GAX25508.1 - 5.3e-28 98.2 75.1 1.6e-11 44.3 17.7 2.7 1 1 2 3 3 3 3 Sulfite exporter TauE/SafE DUF3169 PF11368.8 GAX25508.1 - 0.02 14.4 3.2 0.032 13.7 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) PRP1_N PF06424.12 GAX25508.1 - 7.8 6.9 7.9 14 6.0 7.9 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Form_Nir_trans PF01226.17 GAX25509.1 - 1.7e-63 214.1 22.9 2.2e-63 213.8 22.9 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter LSM PF01423.22 GAX25510.1 - 1.1e-18 66.6 0.0 1.4e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX25510.1 - 4.7e-05 23.5 0.0 6.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain zf-RING_2 PF13639.6 GAX25511.1 - 4.3e-10 39.8 7.2 8.1e-10 38.9 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX25511.1 - 3.7e-08 33.2 1.7 2.9e-07 30.4 0.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAX25511.1 - 8.2e-07 28.7 1.3 7e-06 25.7 0.3 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX25511.1 - 1.1e-06 28.4 0.8 2.1e-06 27.5 0.3 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPM_phosphatase PF04536.14 GAX25511.1 - 3.1e-06 27.4 0.0 5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 TPM domain zf-C3HC4_2 PF13923.6 GAX25511.1 - 1.2e-05 25.0 3.9 5.2e-05 23.0 4.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX25511.1 - 1.9e-05 24.4 4.5 4.3e-05 23.3 4.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX25511.1 - 3.2e-05 23.8 3.7 6.5e-05 22.8 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 GAX25511.1 - 0.00016 21.4 1.1 0.00067 19.4 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAX25511.1 - 0.0011 18.8 6.8 0.052 13.4 6.8 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX25511.1 - 0.0086 16.1 3.9 0.031 14.3 3.9 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 GAX25511.1 - 0.021 15.0 3.2 0.088 13.0 2.6 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAX25511.1 - 0.038 14.3 9.7 0.16 12.3 9.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF1003 PF06210.11 GAX25511.1 - 0.044 13.9 1.0 4.8 7.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Rtf2 PF04641.12 GAX25511.1 - 0.13 11.6 0.6 0.2 11.0 0.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger FANCL_C PF11793.8 GAX25511.1 - 0.35 11.1 5.5 1.2 9.4 5.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Zn-ribbon_8 PF09723.10 GAX25511.1 - 0.36 11.0 6.1 0.51 10.5 2.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 GAX25511.1 - 0.53 10.2 5.6 0.5 10.2 0.3 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 GAX25511.1 - 0.58 9.8 3.7 1.2 8.8 3.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1826 PF08856.11 GAX25512.1 - 6.6e-14 52.3 0.0 4.6e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1826) CBM46 PF18448.1 GAX25512.1 - 0.22 11.8 0.0 0.37 11.1 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain AAA_16 PF13191.6 GAX25513.1 - 8.4e-27 94.6 0.0 2e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX25513.1 - 0.0077 16.5 0.3 0.057 13.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX25513.1 - 0.036 14.0 0.3 0.28 11.1 0.3 2.5 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 GAX25513.1 - 0.05 12.8 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 GAX25513.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 GAX25513.1 - 0.092 12.7 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AdoHcyase PF05221.17 GAX25514.1 - 1.5e-140 467.5 0.0 1.7e-140 467.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GAX25514.1 - 1.3e-79 266.0 3.7 2e-79 265.3 3.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX25514.1 - 3.9e-09 36.1 0.2 6.9e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAX25514.1 - 1.6e-05 24.6 0.1 2.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 GAX25514.1 - 0.00016 21.0 1.4 0.00072 18.9 1.4 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 GAX25514.1 - 0.00049 20.2 0.2 0.0013 18.8 0.2 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 GAX25514.1 - 0.024 14.9 0.1 0.067 13.5 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 GAX25514.1 - 0.067 13.6 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding RNA_pol_Rpb5_N PF03871.14 GAX25515.1 - 6.6e-25 87.5 0.0 7.9e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain LSM PF01423.22 GAX25516.1 - 3.4e-09 36.3 0.1 4e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX25516.1 - 0.027 14.6 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain TPR_12 PF13424.6 GAX25517.1 - 6e-28 97.0 30.6 3.5e-12 46.4 1.1 4.5 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX25517.1 - 2e-16 58.7 17.9 0.00083 19.3 0.1 6.1 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX25517.1 - 9.4e-15 54.0 13.9 0.00035 20.3 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25517.1 - 4.6e-13 48.4 11.9 0.01 15.7 0.4 6.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25517.1 - 3.1e-12 45.6 11.7 0.046 13.8 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25517.1 - 1.5e-10 40.4 6.4 0.0018 18.3 0.2 5.5 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX25517.1 - 3.7e-06 27.4 3.1 1.1 9.8 0.3 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat DUF2225 PF09986.9 GAX25517.1 - 0.00051 19.8 5.2 0.0011 18.7 0.8 2.6 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 GAX25517.1 - 0.00074 19.5 2.0 0.15 12.2 0.0 4.4 3 2 2 5 5 5 1 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 GAX25517.1 - 0.0011 19.0 7.9 2.7 8.1 0.1 4.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 GAX25517.1 - 0.0019 18.7 11.0 0.092 13.4 0.1 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX25517.1 - 0.0049 17.2 3.0 0.2 12.1 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25517.1 - 0.0054 17.4 15.1 2.1 9.1 1.3 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAX25517.1 - 0.0061 17.3 13.1 8.8 7.4 0.1 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 GAX25517.1 - 0.0072 16.1 0.5 0.13 11.9 0.1 2.6 1 1 1 3 3 3 1 26S proteasome subunit RPN7 ANAPC3 PF12895.7 GAX25517.1 - 0.0086 16.3 7.4 0.033 14.4 0.1 3.9 2 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 GAX25517.1 - 0.0098 15.3 2.0 0.53 9.8 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR Fis1_TPR_C PF14853.6 GAX25517.1 - 0.014 15.4 0.3 0.11 12.6 0.1 2.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 GAX25517.1 - 0.018 14.7 2.5 81 3.0 0.0 5.6 6 0 0 6 6 5 0 TPR repeat Mob_Pre PF01076.19 GAX25517.1 - 0.083 12.7 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Plasmid recombination enzyme HemY_N PF07219.13 GAX25517.1 - 0.17 12.1 7.4 16 5.8 0.0 4.3 3 2 2 5 5 5 0 HemY protein N-terminus DUF3128 PF11326.8 GAX25517.1 - 1.1 9.6 4.1 2.2 8.7 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3128) ABC1 PF03109.16 GAX25518.1 - 4.9e-22 78.3 0.9 3.7e-21 75.5 0.0 2.7 3 0 0 3 3 3 1 ABC1 family WaaY PF06176.11 GAX25518.1 - 0.045 13.3 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_M43 PF05572.13 GAX25519.1 - 2.4e-13 50.3 0.0 5.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX25519.1 - 0.00019 21.7 0.2 0.00082 19.6 0.0 2.0 2 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX25519.1 - 0.0036 17.0 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX25519.1 - 0.0037 17.8 0.0 0.0068 16.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX25519.1 - 0.052 13.4 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 GAX25519.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M43 PF05572.13 GAX25520.1 - 1.4e-15 57.5 0.1 4.1e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX25520.1 - 2.5e-05 24.5 0.3 5.7e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX25520.1 - 0.011 16.3 0.0 0.026 15.0 0.0 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX25520.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX25520.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 GAX25520.1 - 0.069 12.8 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 GAX25520.1 - 0.11 11.5 0.4 0.17 10.8 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 GAX25520.1 - 0.13 12.1 0.6 0.23 11.3 0.6 1.6 1 1 0 1 1 1 0 Matrixin AAA PF00004.29 GAX25521.1 - 3.8e-46 156.8 0.0 1e-30 106.9 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX25521.1 - 5.2e-09 36.7 0.1 0.0052 17.2 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAX25521.1 - 1.1e-05 25.4 0.2 0.06 13.3 0.0 3.8 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 GAX25521.1 - 1.3e-05 24.9 0.3 3.5e-05 23.5 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAX25521.1 - 0.00017 21.9 0.0 1 9.6 0.0 3.8 2 2 2 4 4 4 1 AAA domain RuvB_N PF05496.12 GAX25521.1 - 0.00021 21.0 0.0 0.38 10.5 0.0 3.6 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX25521.1 - 0.0056 16.8 0.0 2 8.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 GAX25521.1 - 0.016 15.1 0.1 28 4.6 0.0 3.5 2 1 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 GAX25521.1 - 0.018 14.7 0.0 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAX25521.1 - 0.023 14.6 0.0 11 5.9 0.0 2.5 2 1 0 2 2 2 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 GAX25521.1 - 0.04 13.6 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 GAX25521.1 - 0.044 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 GAX25521.1 - 0.055 13.4 0.0 1.9 8.4 0.0 2.9 2 1 1 3 3 3 0 NTPase Mg_chelatase PF01078.21 GAX25521.1 - 0.075 12.4 0.1 7.8 5.8 0.2 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAX25521.1 - 0.1 13.0 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 GAX25521.1 - 0.11 12.2 0.2 15 5.3 0.3 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 GAX25521.1 - 0.15 11.5 0.0 5.8 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 GAX25521.1 - 0.21 11.4 0.0 23 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAX25521.1 - 0.22 12.1 0.0 33 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain CBF PF03914.17 GAX25522.1 - 2.8e-26 92.5 2.3 2.8e-26 92.5 2.3 3.2 3 1 1 4 4 4 1 CBF/Mak21 family NOC3p PF07540.11 GAX25522.1 - 0.031 14.7 0.0 0.14 12.6 0.0 2.2 1 0 0 1 1 1 0 Nucleolar complex-associated protein TMEM51 PF15345.6 GAX25522.1 - 3.5 7.4 7.9 0.2 11.5 0.5 2.6 2 0 0 2 2 2 0 Transmembrane protein 51 ArfGap PF01412.18 GAX25523.1 - 3.4e-33 114.2 0.1 6.5e-33 113.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SCHIP-1 PF10148.9 GAX25523.1 - 0.0097 15.6 0.5 0.32 10.6 0.2 2.4 2 0 0 2 2 2 1 Schwannomin-interacting protein 1 Mito_carr PF00153.27 GAX25525.1 - 7.3e-37 125.2 3.6 1.8e-12 47.0 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein PPK2 PF03976.14 GAX25526.1 - 6.9e-05 22.5 0.0 0.3 10.5 0.0 2.8 2 1 0 2 2 2 2 Polyphosphate kinase 2 (PPK2) AAA PF00004.29 GAX25527.1 - 1e-31 110.1 0.0 4.5e-31 108.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX25527.1 - 4.6e-06 26.7 0.0 0.0034 17.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX25527.1 - 4.9e-06 27.0 1.6 1.8e-05 25.2 0.2 2.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 GAX25527.1 - 1.6e-05 24.6 0.1 4.6e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_24 PF13479.6 GAX25527.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAX25527.1 - 0.00017 21.4 0.0 0.0013 18.5 0.0 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAX25527.1 - 0.00034 19.9 0.0 0.00052 19.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 GAX25527.1 - 0.00035 20.8 0.0 0.002 18.4 0.0 2.2 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAX25527.1 - 0.00052 20.4 0.0 0.0039 17.6 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 GAX25527.1 - 0.001 19.3 0.1 0.021 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAX25527.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAX25527.1 - 0.002 18.3 0.4 0.01 16.0 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX25527.1 - 0.0036 17.8 0.0 0.012 16.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 GAX25527.1 - 0.0043 17.6 0.0 0.029 14.9 0.0 2.3 2 1 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 GAX25527.1 - 0.0062 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 GAX25527.1 - 0.0087 16.0 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 GAX25527.1 - 0.0088 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX25527.1 - 0.0097 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 GAX25527.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GAX25527.1 - 0.017 14.7 0.1 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 GAX25527.1 - 0.018 14.2 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_17 PF13207.6 GAX25527.1 - 0.043 14.2 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX25527.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 GAX25527.1 - 0.047 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 GAX25527.1 - 0.098 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 GAX25527.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 GAX25527.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAX25527.1 - 0.14 12.1 0.1 2.2 8.2 0.1 2.3 1 1 1 2 2 2 0 Rad17 P-loop domain Hydin_ADK PF17213.3 GAX25527.1 - 0.87 9.8 4.3 1 9.6 1.2 2.5 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Cpn60_TCP1 PF00118.24 GAX25528.1 - 4.4e-93 312.6 16.5 1.4e-92 310.8 16.5 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family MGAT2 PF05060.14 GAX25528.1 - 0.23 10.5 0.3 0.37 9.8 0.3 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) DUF373 PF04123.13 GAX25528.1 - 2.5 7.4 5.6 0.76 9.2 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF373) Fe-S_biosyn PF01521.20 GAX25529.1 - 0.12 12.6 0.0 1.6 8.9 0.0 2.5 1 1 1 2 2 2 0 Iron-sulphur cluster biosynthesis SAP PF02037.27 GAX25530.1 - 2.3e-07 30.4 0.0 4.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain TPR_2 PF07719.17 GAX25530.1 - 3.9e-06 26.6 9.7 0.015 15.4 0.7 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25530.1 - 0.0071 16.5 0.4 3.7 8.0 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25530.1 - 0.017 14.9 7.9 0.72 9.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1965 PF09248.10 GAX25530.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) AMP-binding PF00501.28 GAX25531.1 - 7.4e-34 117.1 0.2 1.2e-33 116.3 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Ank_3 PF13606.6 GAX25531.1 - 6.8e-16 56.8 0.1 0.0032 17.8 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 GAX25531.1 - 2.3e-15 56.7 2.6 4.4e-07 30.3 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX25531.1 - 4.2e-15 56.1 0.0 1.1e-07 32.3 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX25531.1 - 8.8e-13 48.2 2.5 0.00015 22.0 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX25531.1 - 2.2e-09 37.3 2.9 0.099 13.1 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat AMP-binding_C PF13193.6 GAX25531.1 - 0.0026 18.7 0.1 0.01 16.8 0.0 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 GAX25531.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site CaMKII_AD PF08332.10 GAX25532.1 - 5e-33 114.0 1.1 2.5e-15 56.7 0.0 2.0 1 1 1 2 2 2 2 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 GAX25532.1 - 5.1e-05 23.5 0.6 0.011 15.9 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.6 GAX25532.1 - 0.00043 20.7 0.1 0.0047 17.3 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) WD40 PF00400.32 GAX25533.1 - 5.6e-31 106.1 10.2 7.4e-08 32.9 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25533.1 - 8.2e-10 38.9 0.0 0.00056 20.2 0.0 4.7 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX25533.1 - 3.4e-08 32.6 2.2 0.0079 14.9 0.2 4.3 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX25533.1 - 8.6e-05 21.7 2.5 1.5 7.7 0.0 3.9 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAX25533.1 - 0.00082 18.0 0.0 0.012 14.2 0.0 2.4 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 GAX25533.1 - 0.012 14.4 0.1 0.85 8.3 0.0 3.1 3 1 0 3 3 3 0 Nup133 N terminal like eIF2A PF08662.11 GAX25533.1 - 0.012 15.5 0.7 8.7 6.2 0.0 3.5 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 GAX25533.1 - 0.07 13.6 2.7 6.6 7.4 0.0 3.7 5 0 0 5 5 5 0 PQQ-like domain SBP56 PF05694.11 GAX25533.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) DnaJ PF00226.31 GAX25534.1 - 3.8e-15 55.8 0.9 3.8e-15 55.8 0.9 2.5 2 0 0 2 2 2 1 DnaJ domain DUF4523 PF15023.6 GAX25534.1 - 2.6e-05 24.1 2.4 0.00011 22.1 2.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4523) RRM_1 PF00076.22 GAX25534.1 - 0.0019 18.0 0.5 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX25534.1 - 0.026 14.1 0.1 0.086 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM70 PF14967.6 GAX25534.1 - 0.12 11.8 0.1 0.29 10.6 0.1 1.5 2 0 0 2 2 2 0 FAM70 protein Hist_deacetyl PF00850.19 GAX25534.1 - 0.24 10.9 2.7 0.37 10.2 2.7 1.3 1 0 0 1 1 1 0 Histone deacetylase domain DUF4748 PF15932.5 GAX25534.1 - 4.2 7.2 12.4 2.7 7.8 3.4 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4748) zf-RING_2 PF13639.6 GAX25535.1 - 2.2e-11 43.9 10.2 2.2e-11 43.9 10.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 GAX25535.1 - 6e-08 32.8 13.2 3.3e-07 30.5 13.2 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX25535.1 - 1.6e-07 31.0 8.6 1.6e-07 31.0 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX25535.1 - 2.4e-06 27.4 4.0 2.4e-06 27.4 4.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAX25535.1 - 2.8e-06 27.0 8.6 6.7e-06 25.7 8.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX25535.1 - 2.1e-05 24.3 8.7 2.1e-05 24.3 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX25535.1 - 4.3e-05 23.3 5.1 4.3e-05 23.3 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX25535.1 - 9.2e-05 22.3 7.3 9.2e-05 22.3 7.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX25535.1 - 0.00036 20.5 9.1 0.00043 20.3 7.1 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAX25535.1 - 0.004 17.3 8.4 0.004 17.3 8.4 2.4 2 1 0 2 2 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX25535.1 - 0.0066 16.0 7.3 0.0066 16.0 7.3 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX25535.1 - 0.031 14.1 7.6 0.092 12.6 7.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.11 GAX25535.1 - 0.15 12.0 0.9 0.31 11.0 0.4 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-Nse PF11789.8 GAX25535.1 - 0.85 9.5 5.2 2.5 8.0 5.2 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 GAX25535.1 - 0.85 9.8 11.8 0.53 10.5 9.0 2.2 2 0 0 2 2 2 0 RING-variant domain MS_channel PF00924.18 GAX25536.1 - 2.1e-14 53.6 0.0 3.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel His_Phos_1 PF00300.22 GAX25537.1 - 2.7e-21 76.2 0.2 8.3e-11 41.9 0.1 2.5 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) PUFD PF16553.5 GAX25537.1 - 0.13 12.4 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain Acetyltransf_1 PF00583.25 GAX25538.1 - 2.8e-11 43.7 0.0 4.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX25538.1 - 2e-09 37.5 0.1 2.8e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX25538.1 - 1.3e-07 31.5 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 GAX25538.1 - 1.7e-07 31.6 0.2 3.7e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX25538.1 - 0.0027 17.8 0.1 0.0052 16.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAX25538.1 - 0.0052 16.3 0.0 0.0074 15.8 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 GAX25538.1 - 0.076 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MS_channel PF00924.18 GAX25540.1 - 1.6e-09 37.6 0.5 7e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Mechanosensitive ion channel PDDEXK_6 PF04720.12 GAX25540.1 - 0.69 9.8 3.1 1.4 8.8 3.1 1.5 1 0 0 1 1 1 0 PDDEXK-like family of unknown function LRR_6 PF13516.6 GAX25541.1 - 2.7e-05 23.8 1.3 2.2 8.5 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 GAX25541.1 - 0.028 14.9 0.5 70 4.6 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat STI1 PF17830.1 GAX25542.1 - 1.8e-06 27.8 3.8 1.5e-05 24.8 4.1 2.2 2 0 0 2 2 2 1 STI1 domain SAP PF02037.27 GAX25542.1 - 0.68 9.8 5.0 8.7 6.2 0.2 3.0 3 0 0 3 3 3 0 SAP domain Bystin PF05291.11 GAX25543.1 - 1.8e-121 404.9 0.6 2.7e-121 404.3 0.6 1.2 1 0 0 1 1 1 1 Bystin Chalcone_3 PF16036.5 GAX25544.1 - 1.7e-12 47.8 0.0 1.5e-11 44.7 0.0 1.9 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone_2 PF16035.5 GAX25544.1 - 0.013 15.3 0.1 4 7.1 0.1 2.1 1 1 1 2 2 2 0 Chalcone isomerase like Pro_isomerase PF00160.21 GAX25545.1 - 7.1e-38 130.4 0.0 8e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Branch PF02485.21 GAX25546.1 - 1.2e-19 70.8 0.2 1.9e-19 70.2 0.2 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme FAM176 PF14851.6 GAX25546.1 - 0.0038 16.9 0.6 0.0038 16.9 0.6 1.8 2 0 0 2 2 2 1 FAM176 family Tom22 PF04281.13 GAX25546.1 - 4.5 7.1 9.0 17 5.2 9.0 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PBP1_TM PF14812.6 GAX25546.1 - 5.9 7.3 16.9 7.8 7.0 14.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal adh_short PF00106.25 GAX25547.1 - 1.9e-52 177.6 1.6 2.5e-52 177.2 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX25547.1 - 1.9e-43 148.7 3.1 2.9e-43 148.1 3.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX25547.1 - 1e-13 51.6 1.7 1.5e-13 51.1 1.7 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAX25547.1 - 3.6e-05 23.7 2.1 4.8e-05 23.3 2.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAX25547.1 - 4.6e-05 22.7 1.1 6.4e-05 22.2 1.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAX25547.1 - 7.4e-05 22.8 0.5 0.00017 21.6 0.5 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX25547.1 - 0.00019 21.7 1.7 0.00028 21.1 1.3 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAX25547.1 - 0.00065 19.2 1.3 0.0019 17.7 1.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 GAX25547.1 - 0.0048 16.3 0.1 0.0077 15.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAX25547.1 - 0.019 14.8 1.0 0.032 14.1 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 GAX25547.1 - 0.066 12.3 3.2 0.033 13.3 1.2 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GAX25547.1 - 0.11 11.9 0.4 0.28 10.5 0.4 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Aminotran_5 PF00266.19 GAX25548.1 - 6.2e-18 64.9 0.0 2.3e-10 40.0 0.0 2.8 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAX25548.1 - 0.0051 15.4 0.0 0.0079 14.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 GAX25548.1 - 0.0077 14.9 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 GAX25548.1 - 0.027 13.8 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Thioredoxin PF00085.20 GAX25549.1 - 1.4e-07 31.4 0.0 3.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 GAX25549.1 - 1.8e-05 23.8 0.1 2.8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Phosducin DIM1 PF02966.16 GAX25549.1 - 0.042 13.6 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Phasin PF05597.11 GAX25549.1 - 0.079 13.0 5.4 0.13 12.3 0.0 2.9 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SUIM_assoc PF16619.5 GAX25549.1 - 3.4 7.8 14.2 0.16 12.1 5.9 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ATG22 PF11700.8 GAX25550.1 - 2.9e-15 55.9 32.8 4.6e-11 42.0 20.1 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAX25550.1 - 7.7e-11 41.5 32.5 7.7e-11 41.5 32.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ParB_C PF18064.1 GAX25551.1 - 0.071 13.3 0.1 0.49 10.6 0.1 2.2 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal TIM PF00121.18 GAX25552.1 - 3.1e-75 252.7 0.0 3.6e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase 7tm_3 PF00003.22 GAX25553.1 - 7.7e-21 74.9 15.4 1.3e-20 74.1 15.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Pardaxin PF07425.11 GAX25553.1 - 0.029 14.0 0.2 0.1 12.2 0.2 1.9 1 0 0 1 1 1 0 Pardaxin GARS_A PF01071.19 GAX25554.1 - 1.5e-77 259.8 0.0 2.4e-77 259.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 GAX25554.1 - 3.5e-41 140.9 0.0 7.7e-41 139.8 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase AIRS_C PF02769.22 GAX25554.1 - 7.2e-38 130.2 0.0 4e-37 127.7 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 GAX25554.1 - 2.1e-29 102.2 0.2 7.3e-29 100.4 0.2 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 GAX25554.1 - 2.2e-21 75.9 1.7 4.4e-21 75.0 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 GAX25554.1 - 2.6e-14 53.7 1.4 1.2e-13 51.5 1.4 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 GAX25554.1 - 1.4e-05 25.3 0.0 2.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GAX25554.1 - 0.00067 19.2 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 GAX25554.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Peptidase_S8 PF00082.22 GAX25555.1 - 7.7e-37 127.1 9.3 3.9e-36 124.8 7.4 2.3 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 GAX25555.1 - 0.0047 17.6 0.2 0.0086 16.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 SR-25 PF10500.9 GAX25555.1 - 1.6 8.3 4.1 2.6 7.6 4.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S8 PF00082.22 GAX25556.1 - 2.4e-39 135.4 4.7 4e-38 131.4 4.7 2.0 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAX25556.1 - 0.079 13.6 1.1 0.3 11.8 1.1 2.0 1 1 0 1 1 1 0 Peptidase inhibitor I9 Mon1 PF03164.14 GAX25557.1 - 8.3e-24 84.4 0.0 1.1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Beta_helix PF13229.6 GAX25558.1 - 1.2e-08 34.9 7.4 1.5e-06 28.2 2.1 2.6 1 1 1 2 2 2 2 Right handed beta helix region DUF1565 PF07602.11 GAX25558.1 - 0.0059 16.0 2.7 1.2 8.4 0.0 3.0 1 1 0 2 2 2 2 Protein of unknown function (DUF1565) Gal-3-0_sulfotr PF06990.11 GAX25559.1 - 1.6e-09 37.2 7.0 9.2e-07 28.1 3.2 3.0 1 1 1 2 2 2 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 GAX25559.1 - 4.5e-07 30.0 0.1 1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 Sulfotransferase family Nucleotid_trans PF03407.16 GAX25559.1 - 0.022 14.7 0.5 0.051 13.5 0.1 1.8 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase DUF4635 PF15466.6 GAX25559.1 - 0.035 13.6 0.0 0.12 11.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) Nairovirus_M PF07948.11 GAX25559.1 - 0.14 10.4 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DUF2418 PF10332.9 GAX25559.1 - 0.73 10.4 2.4 1.2 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) GST_N_3 PF13417.6 GAX25560.1 - 1.1e-22 80.2 0.2 3.4e-12 46.6 0.0 3.4 3 0 0 3 3 3 3 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAX25560.1 - 7.2e-15 55.0 0.1 3.1e-09 36.9 0.0 3.3 3 1 0 3 3 3 2 Glutaredoxin GST_N_2 PF13409.6 GAX25560.1 - 3.8e-06 27.1 0.0 0.16 12.3 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 GAX25560.1 - 0.0088 16.3 0.0 0.37 11.1 0.0 2.4 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein ABC_membrane PF00664.23 GAX25561.1 - 1.2e-56 192.4 20.8 5.1e-30 105.1 10.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX25561.1 - 2.6e-34 118.7 0.3 3.9e-24 85.7 0.0 3.5 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 GAX25561.1 - 2.1e-06 27.3 4.5 0.033 13.6 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX25561.1 - 2e-05 24.8 0.6 0.0092 16.3 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAX25561.1 - 0.00051 20.0 3.8 1.5 8.5 0.0 4.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 GAX25561.1 - 0.0011 17.7 0.1 0.0018 17.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX25561.1 - 0.0015 18.9 0.8 0.63 10.4 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain DEAD PF00270.29 GAX25561.1 - 0.0016 18.2 0.0 1.8 8.3 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 GAX25561.1 - 0.0027 17.5 0.1 0.17 11.7 0.0 2.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 GAX25561.1 - 0.0051 16.5 0.2 2.3 8.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAX25561.1 - 0.0075 16.0 2.6 3.5 7.3 0.0 3.9 3 1 1 4 4 4 1 IstB-like ATP binding protein TsaE PF02367.17 GAX25561.1 - 0.012 15.6 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 GAX25561.1 - 0.015 15.2 0.6 5 7.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 GAX25561.1 - 0.032 14.3 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 GAX25561.1 - 0.032 14.4 0.4 0.28 11.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 GAX25561.1 - 0.048 13.7 1.3 0.2 11.7 0.1 2.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_18 PF13238.6 GAX25561.1 - 0.056 14.0 0.0 3.1 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 GAX25561.1 - 0.062 12.2 0.0 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain T2SSE PF00437.20 GAX25561.1 - 0.071 12.2 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.6 GAX25561.1 - 0.11 12.3 0.3 3 7.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GAX25561.1 - 0.11 11.9 0.1 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAX25561.1 - 0.17 11.6 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAX25561.1 - 0.19 11.7 0.6 1.3 8.9 0.1 2.6 2 1 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 GAX25561.1 - 0.32 10.6 3.8 31 4.1 0.1 3.7 3 1 1 4 4 4 0 AAA domain MatE PF01554.18 GAX25563.1 - 5.7e-17 61.8 25.7 1.3e-10 41.1 8.6 2.6 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAX25563.1 - 2.3e-09 37.4 7.0 2.3e-09 37.4 7.0 4.0 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain PQ-loop PF04193.14 GAX25564.1 - 1.1e-07 31.5 1.0 0.0017 18.1 0.1 2.9 3 0 0 3 3 3 2 PQ loop repeat WD40 PF00400.32 GAX25565.1 - 2.8e-11 43.8 5.9 0.0023 18.7 0.3 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25565.1 - 0.017 15.4 0.0 20 5.6 0.0 3.7 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX25565.1 - 0.018 15.6 5.0 89 3.8 0.0 4.6 4 0 0 4 4 4 0 PQQ-like domain Antimicrobial22 PF16047.5 GAX25565.1 - 0.091 12.6 1.0 0.2 11.6 1.0 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide NOA36 PF06524.12 GAX25565.1 - 1.2 8.4 11.0 1.8 7.8 11.0 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 GAX25565.1 - 1.4 8.3 12.0 2 7.7 12.0 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GAX25565.1 - 9.5 4.2 13.5 13 3.8 13.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CLU PF13236.6 GAX25566.1 - 5.9e-65 219.2 0.0 1.1e-64 218.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAX25566.1 - 5.7e-36 124.2 1.6 6.6e-35 120.7 0.0 3.2 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 GAX25566.1 - 3.4e-10 40.1 4.5 0.0017 18.6 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat CLU_N PF15044.6 GAX25566.1 - 0.0035 17.7 0.0 1.1 9.7 0.0 3.4 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TERB2 PF15101.6 GAX25566.1 - 0.079 13.0 4.7 0.24 11.4 4.7 1.8 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CNDH2_C PF16858.5 GAX25566.1 - 0.16 11.8 10.5 0.024 14.5 5.6 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SUIM_assoc PF16619.5 GAX25569.1 - 0.09 12.9 0.2 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Kelch_1 PF01344.25 GAX25570.1 - 9e-33 111.6 1.8 5.9e-08 32.2 0.4 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAX25570.1 - 2.1e-30 103.5 1.3 2.9e-07 30.2 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAX25570.1 - 5.1e-29 100.0 17.4 5.6e-07 29.7 0.1 8.1 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GAX25570.1 - 8.5e-28 95.9 3.7 1.7e-05 24.7 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 GAX25570.1 - 1.5e-27 94.9 1.1 1.1e-05 25.5 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAX25570.1 - 9e-27 92.8 5.3 8.3e-05 22.5 0.1 6.8 6 1 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 GAX25570.1 - 1.7e-24 86.1 1.1 3.4e-24 85.2 0.3 1.9 1 1 1 2 2 2 1 BTB/POZ domain TPT PF03151.16 GAX25571.1 - 2e-99 332.6 19.4 2.4e-99 332.4 19.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX25571.1 - 9e-09 35.6 30.2 0.00011 22.4 9.6 2.8 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 GAX25571.1 - 0.0034 16.6 17.0 0.0029 16.9 15.1 1.7 1 1 1 2 2 2 1 UAA transporter family DDOST_48kD PF03345.14 GAX25571.1 - 0.18 10.6 0.3 0.34 9.7 0.3 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta NAD_binding_8 PF13450.6 GAX25572.1 - 0.0059 16.8 0.2 0.044 14.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAX25572.1 - 0.039 12.7 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 GAX25572.1 - 0.12 11.4 0.1 0.74 8.8 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Aha1_N PF09229.11 GAX25573.1 - 1.1e-25 90.5 0.6 1.1e-25 90.5 0.6 3.0 3 2 1 4 4 2 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.17 GAX25573.1 - 2.6e-18 64.6 8.3 4.8e-08 32.5 0.4 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25573.1 - 6.9e-18 63.7 2.2 9.1e-08 31.6 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX25573.1 - 1.7e-12 46.8 5.3 3.7e-05 23.3 0.3 3.5 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 GAX25573.1 - 1.6e-10 40.9 3.3 3e-05 24.5 0.5 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25573.1 - 6.7e-09 36.3 2.1 1.8e-05 25.3 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25573.1 - 2.3e-08 33.6 0.4 0.071 13.4 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX25573.1 - 1.1e-07 31.9 0.9 4.6e-07 29.9 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX25573.1 - 1.5e-07 31.6 4.6 0.011 16.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX25573.1 - 1.6e-07 31.2 0.2 0.019 15.0 0.0 2.8 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 GAX25573.1 - 3.4e-07 30.7 2.4 3.4e-07 30.7 2.4 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX25573.1 - 1.1e-05 25.8 4.7 4.8e-05 23.7 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX25573.1 - 0.00019 21.6 1.0 0.0059 16.9 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25573.1 - 0.00028 20.7 0.6 0.018 15.1 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX25573.1 - 0.00029 20.6 3.8 0.18 11.7 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX25573.1 - 0.00088 19.5 1.5 0.0025 18.0 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 GAX25573.1 - 1.1 10.1 3.9 1.1 10.0 1.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat UCH PF00443.29 GAX25574.1 - 4.8e-40 137.7 0.1 7.8e-40 137.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX25574.1 - 3.8e-12 46.4 1.0 3.3e-07 30.2 0.0 2.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Mso1_Sec1_bdg PF14475.6 GAX25574.1 - 0.19 11.4 0.2 0.19 11.4 0.2 3.4 3 0 0 3 3 3 0 Sec1-binding region of Mso1 PseudoU_synth_2 PF00849.22 GAX25575.1 - 5e-31 107.9 0.0 1e-30 106.9 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase Abhydrolase_6 PF12697.7 GAX25576.1 - 5.7e-06 27.1 0.0 9.6e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX25576.1 - 2.9e-05 23.4 0.1 0.0001 21.7 0.1 1.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 GAX25576.1 - 0.00038 20.1 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 GAX25576.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase BAAT_C PF08840.11 GAX25576.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pescadillo_N PF06732.11 GAX25577.1 - 4.6e-59 200.2 0.0 4.6e-59 200.2 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 GAX25577.1 - 0.00011 22.5 0.2 0.00091 19.6 0.0 2.6 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Nop53 PF07767.11 GAX25577.1 - 1.7 7.9 47.2 0.049 13.0 30.4 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Astro_capsid_p PF12226.8 GAX25577.1 - 5.2 6.1 22.8 0.44 9.7 5.9 2.3 2 0 0 2 2 2 0 Turkey astrovirus capsid protein MttA_Hcf106 PF02416.16 GAX25578.1 - 1.2e-07 30.9 4.0 2e-07 30.3 4.0 1.5 1 1 0 1 1 1 1 mttA/Hcf106 family Strep_pep PF14404.6 GAX25579.1 - 0.039 14.2 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species RskA PF10099.9 GAX25581.1 - 3.3 8.0 7.1 2.5 8.3 1.6 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Ribosomal_L39 PF00832.20 GAX25583.1 - 0.12 12.0 2.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L39 protein zf-MYND PF01753.18 GAX25585.1 - 7e-06 26.0 11.3 1.5e-05 25.0 11.3 1.6 1 0 0 1 1 1 1 MYND finger CTK3_C PF12350.8 GAX25585.1 - 0.13 12.4 0.3 0.84 9.8 0.0 2.1 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus zf-MYND PF01753.18 GAX25586.1 - 4e-08 33.2 14.1 9.4e-08 32.0 14.1 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 GAX25586.1 - 1.2 9.3 6.5 3 8.0 6.5 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_S28 PF05577.12 GAX25587.1 - 1.7e-49 168.8 0.0 3.5e-49 167.8 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Mpv17_PMP22 PF04117.12 GAX25588.1 - 3.4e-13 49.6 0.6 3.4e-13 49.6 0.6 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF2183 PF09949.9 GAX25590.1 - 4.5e-05 23.7 0.0 8.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Rad60-SLD PF11976.8 GAX25591.1 - 2.3e-14 52.9 0.5 8.8e-14 51.1 0.2 2.2 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAX25591.1 - 0.00011 21.8 0.1 0.00032 20.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family TFIIF_alpha PF05793.12 GAX25591.1 - 2.4 6.7 16.5 3.7 6.0 16.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPT PF03151.16 GAX25592.1 - 5.6e-35 121.1 17.0 7.1e-35 120.8 17.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAX25592.1 - 0.00011 21.5 17.0 0.00011 21.5 17.0 2.1 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.20 GAX25592.1 - 0.00065 19.9 29.9 0.058 13.6 8.9 3.2 2 1 0 2 2 2 2 EamA-like transporter family HMG_box PF00505.19 GAX25593.1 - 9.8e-15 54.7 0.4 2.1e-14 53.6 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX25593.1 - 6.5e-08 33.1 0.2 1.9e-07 31.5 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain Nefa_Nip30_N PF10187.9 GAX25593.1 - 0.93 9.9 5.8 20 5.6 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Fasciclin PF02469.22 GAX25595.1 - 7.5e-43 145.8 4.2 2.9e-14 53.4 0.2 4.2 4 0 0 4 4 4 4 Fasciclin domain Ank_2 PF12796.7 GAX25596.1 - 3.3e-23 82.1 0.1 6.3e-09 36.3 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX25596.1 - 1.5e-16 60.2 2.0 8.8e-05 22.7 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX25596.1 - 1.7e-14 52.5 3.5 0.071 13.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 GAX25596.1 - 3.5e-09 37.0 0.5 7.2e-06 26.4 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX25596.1 - 9.7e-08 32.1 4.5 0.31 11.6 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat PBP_like_2 PF12849.7 GAX25597.1 - 2.7e-31 109.3 0.1 4.8e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 PBP superfamily domain DUF1515 PF07439.11 GAX25597.1 - 0.0019 18.2 3.1 0.13 12.3 4.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1515) Spc7 PF08317.11 GAX25597.1 - 0.18 10.6 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fasciclin PF02469.22 GAX25598.1 - 3.4e-43 146.9 4.9 7.7e-22 77.9 0.5 3.3 4 0 0 4 4 4 2 Fasciclin domain Glyco_tranf_2_4 PF13704.6 GAX25599.1 - 0.00012 22.5 0.3 0.00034 21.1 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Med26 PF08711.11 GAX25599.1 - 0.047 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Fasciclin PF02469.22 GAX25600.1 - 1.1e-37 129.1 0.1 1.9e-22 79.8 0.1 2.4 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 GAX25602.1 - 1.3e-46 157.9 0.1 4.4e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 GAX25603.1 - 5.9e-30 104.1 0.0 2.6e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 GAX25604.1 - 1.2e-67 225.9 0.0 4.5e-16 59.2 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain HMD PF03201.16 GAX25604.1 - 0.025 14.8 2.7 2.6 8.3 0.1 3.7 4 0 0 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Fasciclin PF02469.22 GAX25605.1 - 3.3e-29 101.7 0.0 7e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain SOCS PF12610.8 GAX25606.1 - 0.074 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Suppressor of cytokine signalling PC-Esterase PF13839.6 GAX25609.1 - 0.0026 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Melibiase PF02065.18 GAX25609.1 - 0.045 12.7 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 Melibiase PT PF04886.12 GAX25610.1 - 0.0049 16.4 3.2 0.0049 16.4 3.2 1.8 2 0 0 2 2 2 1 PT repeat Conotoxin_I2 PF17557.2 GAX25610.1 - 0.15 12.2 8.4 0.63 10.2 8.4 2.1 1 0 0 1 1 1 0 I2-superfamily conotoxins FAM177 PF14774.6 GAX25612.1 - 3.3 8.1 10.9 1.2 9.5 6.5 2.5 2 1 1 3 3 3 0 FAM177 family HAD_2 PF13419.6 GAX25614.1 - 3.1e-13 50.2 0.0 6.2e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX25614.1 - 9.9e-12 45.6 0.0 1.2e-10 42.1 0.0 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX25614.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GAX25614.1 - 9.8e-06 26.1 0.1 1.6e-05 25.4 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 GAX25614.1 - 0.12 12.2 2.1 1.3 8.9 0.0 2.4 2 1 0 2 2 2 0 Acid Phosphatase DUF2385 PF09539.10 GAX25615.1 - 0.12 12.9 0.2 0.23 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Acetyltransf_7 PF13508.7 GAX25619.1 - 0.013 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LAP1C PF05609.12 GAX25620.1 - 0.17 10.9 8.6 0.19 10.8 8.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) FAM220 PF15487.6 GAX25620.1 - 4 7.0 12.2 6 6.4 12.2 1.3 1 0 0 1 1 1 0 FAM220 family YqfD PF06898.11 GAX25620.1 - 8.9 5.0 7.8 13 4.5 7.8 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD DOT1 PF08123.13 GAX25621.1 - 5.7e-12 45.6 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 GAX25621.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase EF-hand_1 PF00036.32 GAX25622.1 - 2.6e-41 136.1 14.6 2.9e-10 38.9 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAX25622.1 - 1.3e-34 118.4 3.5 5.3e-18 65.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX25622.1 - 1.8e-30 102.3 8.0 1.3e-09 37.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAX25622.1 - 2.3e-30 104.2 12.9 2.1e-16 59.5 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAX25622.1 - 1.9e-27 93.5 10.4 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAX25622.1 - 7.2e-15 55.1 0.2 7.3e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAX25622.1 - 1.9e-09 37.4 0.7 0.00013 21.8 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAX25622.1 - 1.3e-07 31.9 0.0 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 GAX25622.1 - 3.1e-06 28.0 0.0 0.00016 22.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 GAX25622.1 - 0.00013 21.9 2.0 0.28 11.3 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 GAX25622.1 - 0.00013 21.9 1.6 0.00037 20.5 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 GAX25622.1 - 0.00055 20.1 2.3 0.044 14.0 0.3 2.8 1 1 3 4 4 4 1 Dockerin type I domain DUF3349 PF11829.8 GAX25622.1 - 0.0022 18.7 0.3 1.4 9.7 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 GAX25622.1 - 0.0029 17.5 0.9 0.21 11.5 0.3 3.2 1 1 1 2 2 2 1 Caleosin related protein TerB PF05099.13 GAX25622.1 - 0.0036 17.3 0.2 1.3 9.0 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF5580 PF17743.1 GAX25622.1 - 0.011 14.3 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF4497 PF14924.6 GAX25622.1 - 0.013 15.9 0.0 6.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 GAX25622.1 - 0.02 15.2 0.7 0.73 10.2 0.1 2.5 3 0 0 3 3 2 0 RNA polymerase Rpb4 SurA_N_2 PF13623.6 GAX25622.1 - 0.032 14.1 0.5 1.7 8.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 GAX25622.1 - 0.034 14.3 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF853 PF05872.12 GAX25622.1 - 0.037 12.6 0.1 0.62 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 GAX25622.1 - 0.076 13.3 0.1 11 6.3 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein FGAR-AT_linker PF18072.1 GAX25622.1 - 0.093 13.3 0.3 4.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain SapB_1 PF05184.15 GAX25622.1 - 0.18 11.9 2.4 22 5.2 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 PseudoU_synth_1 PF01416.20 GAX25623.1 - 1.5e-24 86.5 0.0 7.3e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase TMEM51 PF15345.6 GAX25624.1 - 0.38 10.6 9.6 0.66 9.8 9.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 PROL5-SMR PF15621.6 GAX25624.1 - 0.59 10.7 13.4 0.29 11.7 7.7 2.5 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF5427 PF10310.9 GAX25624.1 - 3.1 6.6 8.9 4.8 6.0 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Peptidase_S64 PF08192.11 GAX25624.1 - 6.6 5.1 9.3 8.3 4.8 9.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Transglut_core PF01841.19 GAX25625.1 - 3e-13 50.2 1.0 3e-13 50.2 1.0 2.3 2 1 1 3 3 3 1 Transglutaminase-like superfamily DUF553 PF04473.12 GAX25625.1 - 0.00012 21.6 0.0 0.00062 19.3 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like domain RasGAP_C PF03836.15 GAX25625.1 - 0.11 12.6 3.5 8.4 6.5 0.1 2.4 2 0 0 2 2 2 0 RasGAP C-terminus RRM_1 PF00076.22 GAX25626.1 - 2.6e-20 72.0 0.1 5.7e-20 70.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_4 PF13717.6 GAX25626.1 - 1.4e-05 24.9 0.5 2.8e-05 23.9 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.6 GAX25626.1 - 0.0032 17.2 0.7 0.0096 15.7 0.0 2.0 2 0 0 2 2 2 1 zinc-ribbon domain zf-CSL PF05207.13 GAX25626.1 - 0.1 12.3 1.4 0.19 11.4 0.5 1.9 2 0 0 2 2 2 0 CSL zinc finger zinc_ribbon_12 PF11331.8 GAX25626.1 - 0.34 10.8 5.5 1.1 9.1 0.4 2.8 2 1 1 3 3 3 0 Probable zinc-ribbon domain RNA_POL_M_15KD PF02150.16 GAX25626.1 - 3.9 7.4 5.4 5.8 6.9 0.2 2.6 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit STPPase_N PF16891.5 GAX25627.1 - 0.12 12.8 0.5 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain HMG_box PF00505.19 GAX25628.1 - 8.4e-31 106.2 22.5 6.4e-18 64.9 7.2 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX25628.1 - 2.1e-23 82.7 18.1 6.6e-12 45.9 5.9 2.5 2 0 0 2 2 2 2 HMG-box domain CinA PF02464.17 GAX25628.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Competence-damaged protein VitD-bind_III PF09164.10 GAX25628.1 - 0.15 12.1 0.0 0.64 10.0 0.0 2.0 1 0 0 1 1 1 0 Vitamin D binding protein, domain III MATalpha_HMGbox PF04769.12 GAX25628.1 - 0.16 11.3 1.8 0.26 10.6 1.8 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Condensin2nSMC PF12422.8 GAX25628.1 - 0.24 11.6 0.7 4 7.6 0.1 2.2 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Endonuc_Holl PF10107.9 GAX25628.1 - 8.6 6.2 8.7 0.48 10.3 1.7 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase RNase_PH PF01138.21 GAX25629.1 - 1.4e-06 28.9 0.2 7.7e-06 26.4 0.0 2.3 2 2 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX25629.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 AAA PF00004.29 GAX25630.1 - 4e-41 140.5 0.0 6.6e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 GAX25630.1 - 8.6e-19 67.4 4.7 8.6e-19 67.4 4.7 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 GAX25630.1 - 2.9e-16 59.2 0.0 1.1e-15 57.4 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 GAX25630.1 - 4.3e-07 30.3 0.2 0.017 15.4 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_lid_3 PF17862.1 GAX25630.1 - 5.8e-07 29.2 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX25630.1 - 2.5e-05 24.7 0.1 0.00011 22.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAX25630.1 - 3.4e-05 23.7 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 GAX25630.1 - 8.4e-05 22.4 0.1 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX25630.1 - 0.00014 21.9 0.1 0.0012 18.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX25630.1 - 0.00014 21.1 0.0 0.00034 19.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 GAX25630.1 - 0.00017 21.7 0.0 0.00045 20.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 GAX25630.1 - 0.00021 21.3 0.0 0.00059 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAX25630.1 - 0.00027 20.7 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 GAX25630.1 - 0.0025 18.0 0.0 0.0069 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAX25630.1 - 0.0025 17.6 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 GAX25630.1 - 0.0027 18.3 0.0 0.008 16.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 GAX25630.1 - 0.0078 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 GAX25630.1 - 0.0087 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.26 GAX25630.1 - 0.02 14.6 0.0 0.13 12.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 GAX25630.1 - 0.034 14.6 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAX25630.1 - 0.036 13.4 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 GAX25630.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 GAX25630.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 GAX25630.1 - 0.073 12.6 0.2 0.71 9.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain Zn_ribbon_SprT PF17283.2 GAX25630.1 - 0.095 12.6 1.9 0.28 11.1 1.9 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain AFG1_ATPase PF03969.16 GAX25630.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase PhoH PF02562.16 GAX25630.1 - 0.11 12.0 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 GAX25630.1 - 0.11 12.5 0.0 0.85 9.5 0.0 2.1 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 GAX25630.1 - 0.11 12.4 0.0 3.1 7.6 0.0 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TPR_1 PF00515.28 GAX25630.1 - 0.16 11.9 0.7 0.42 10.5 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat KAP_NTPase PF07693.14 GAX25630.1 - 0.18 11.0 0.0 2.7 7.1 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain TPR_7 PF13176.6 GAX25630.1 - 0.55 10.4 1.9 0.93 9.7 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX25630.1 - 0.63 10.3 2.9 0.49 10.6 0.3 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat WW PF00397.26 GAX25631.1 - 2.6e-21 75.4 6.1 2.5e-11 43.5 0.3 2.5 2 0 0 2 2 2 2 WW domain FYVE PF01363.21 GAX25631.1 - 5.3e-17 61.7 7.9 2.1e-16 59.8 7.9 2.2 1 0 0 1 1 1 1 FYVE zinc finger HEAT PF02985.22 GAX25631.1 - 0.13 12.6 12.3 27 5.4 0.0 8.4 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 GAX25631.1 - 0.29 11.7 27.4 4.4 7.9 0.1 8.1 7 2 1 8 8 8 0 HEAT-like repeat p450 PF00067.22 GAX25632.1 - 4.7e-78 263.0 0.0 8e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DnaGprimase_HBD PF16730.5 GAX25632.1 - 0.022 14.8 0.7 0.041 14.0 0.3 1.6 2 0 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain Cnl2_NKP2 PF09447.10 GAX25632.1 - 0.094 12.9 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 Cnl2/NKP2 family protein RVP PF00077.20 GAX25633.1 - 0.0032 17.7 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GAX25633.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CHASE PF03924.13 GAX25634.1 - 0.046 13.7 0.5 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 CHASE domain YlbE PF14003.6 GAX25634.1 - 1.1 9.8 7.2 6 7.4 0.2 5.1 4 0 0 4 4 4 0 YlbE-like protein LAGLIDADG_3 PF14528.6 GAX25634.1 - 4.8 7.6 6.3 43 4.5 0.0 3.8 3 1 1 4 4 4 0 LAGLIDADG-like domain KASH_CCD PF14662.6 GAX25635.1 - 0.0053 16.6 6.5 0.0053 16.6 6.5 10.7 1 1 9 11 11 11 2 Coiled-coil region of CCDC155 or KASH DUF5342 PF17277.2 GAX25635.1 - 1.5 9.2 3.4 20 5.6 0.2 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5342) UDPG_MGDP_dh_C PF03720.15 GAX25635.1 - 2.6 8.5 5.7 1.5 9.3 0.2 3.7 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DnaJ PF00226.31 GAX25636.1 - 9.3e-29 99.4 4.1 4.1e-28 97.3 4.1 2.2 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 GAX25636.1 - 1.7e-22 77.7 34.9 3.9e-07 29.7 0.9 9.5 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25636.1 - 1e-21 75.8 26.9 5.4e-08 32.3 0.2 8.9 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAX25636.1 - 5.1e-16 58.7 23.7 0.0012 19.1 0.4 6.7 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25636.1 - 7.4e-16 57.0 17.4 5.6e-05 23.0 0.0 9.5 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25636.1 - 9.2e-15 55.0 33.3 0.00066 20.3 0.4 7.9 5 3 2 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25636.1 - 2.2e-14 52.3 25.8 0.0006 19.7 0.4 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAX25636.1 - 2.4e-12 46.6 24.3 0.00026 21.6 0.1 8.3 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAX25636.1 - 6.9e-12 44.9 23.8 5.3e-05 22.8 0.0 8.1 6 2 1 7 7 7 3 TPR repeat ANAPC3 PF12895.7 GAX25636.1 - 1.6e-11 44.2 22.1 4.1e-07 30.1 0.4 5.6 4 2 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAX25636.1 - 4.8e-11 43.0 19.0 0.013 16.0 0.4 6.6 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_9 PF13371.6 GAX25636.1 - 1.1e-07 31.9 17.0 0.021 15.0 0.3 5.1 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 GAX25636.1 - 0.00013 22.3 12.6 0.53 11.1 0.8 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat PRAI PF00697.22 GAX25636.1 - 0.00041 20.2 2.5 0.00086 19.1 2.5 1.5 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF627 PF04781.12 GAX25636.1 - 0.0033 17.4 8.0 3.8 7.6 0.1 5.6 4 2 1 5 5 5 1 Protein of unknown function (DUF627) SHNi-TPR PF10516.9 GAX25636.1 - 0.0097 15.3 7.2 0.012 15.0 0.0 4.4 7 0 0 7 7 7 1 SHNi-TPR TPR_6 PF13174.6 GAX25636.1 - 0.025 15.2 22.9 0.64 10.8 0.1 7.6 8 0 0 8 8 6 0 Tetratricopeptide repeat MIT PF04212.18 GAX25636.1 - 0.027 14.5 23.5 0.7 10.0 0.9 6.6 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain Sec23_trunk PF04811.15 GAX25636.1 - 0.038 13.6 0.7 0.061 12.9 0.0 1.6 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Ribosomal_S8e PF01201.22 GAX25636.1 - 0.052 13.7 0.1 0.21 11.8 0.1 2.0 1 1 0 1 1 1 0 Ribosomal protein S8e TPR_10 PF13374.6 GAX25636.1 - 0.06 13.2 23.4 5.2 7.1 0.3 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX25636.1 - 0.51 10.8 0.1 0.51 10.8 0.1 5.4 8 0 0 8 8 3 0 Tetratricopeptide repeat Phage_holin_6_1 PF09682.10 GAX25636.1 - 1.2 9.6 5.2 5.3 7.5 5.2 2.1 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) TPR_3 PF07720.12 GAX25636.1 - 1.2 9.2 9.4 2 8.5 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat CorA PF01544.18 GAX25636.1 - 4.2 6.6 6.0 0.74 9.1 1.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Nrap_D3 PF17404.2 GAX25637.1 - 2.6e-32 112.1 0.2 1.5e-31 109.6 0.0 2.4 3 0 0 3 3 3 1 Nrap protein domain 3 Nrap_D5 PF17406.2 GAX25637.1 - 2.9e-30 105.2 0.0 6.7e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 GAX25637.1 - 2.1e-27 95.9 0.2 5.9e-27 94.4 0.1 1.8 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 GAX25637.1 - 1.1e-17 64.5 0.9 2.4e-17 63.4 0.9 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 GAX25637.1 - 2.6e-16 59.7 0.1 4.3e-11 42.8 0.0 3.2 3 0 0 3 3 3 2 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 GAX25637.1 - 1.3e-12 48.1 0.0 3.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 PAP_central PF04928.17 GAX25637.1 - 0.0023 17.0 0.0 0.0066 15.4 0.0 1.7 1 0 0 1 1 1 1 Poly(A) polymerase central domain Tim17 PF02466.19 GAX25638.1 - 1.3e-28 99.5 7.9 1.9e-28 99.1 7.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TPR_1 PF00515.28 GAX25639.1 - 0.024 14.5 2.8 4.6 7.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX25639.1 - 0.065 13.5 4.4 4.1 7.8 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-C4 PF00105.18 GAX25639.1 - 0.071 13.6 0.3 14 6.2 0.1 2.4 1 1 1 2 2 2 0 Zinc finger, C4 type (two domains) TPR_10 PF13374.6 GAX25639.1 - 0.13 12.2 8.5 2.2 8.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX25639.1 - 0.92 9.8 3.1 3.1 8.1 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAX25639.1 - 4 8.0 6.9 9.3 6.9 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Peptidase_S10 PF00450.22 GAX25640.1 - 1.4e-117 393.7 2.9 1.7e-117 393.4 2.9 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2695 PF10905.8 GAX25641.1 - 0.016 15.4 0.2 0.42 10.9 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) FGE-sulfatase PF03781.16 GAX25642.1 - 1.2e-41 143.0 17.7 1.3e-41 142.9 12.4 3.1 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 Zn_Tnp_IS1 PF03811.13 GAX25642.1 - 0.16 11.8 0.8 4.6 7.1 0.1 2.4 2 0 0 2 2 2 0 InsA N-terminal domain RPA43_OB PF17875.1 GAX25642.1 - 3.4 8.3 7.4 14 6.3 2.1 2.9 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I eIF3_subunit PF08597.10 GAX25642.1 - 3.9 7.3 15.6 14 5.5 15.6 1.9 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Globin PF00042.22 GAX25643.1 - 4.4e-15 56.2 0.0 5.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Globin Cupin_8 PF13621.6 GAX25644.1 - 1.5e-18 67.4 2.1 6e-17 62.2 0.2 2.3 2 1 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 GAX25644.1 - 0.0038 16.7 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 GAX25644.1 - 0.074 13.5 0.2 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase Leg1 PF05612.12 GAX25645.1 - 1.3e-13 50.8 1.5 3e-13 49.6 1.5 1.5 1 1 0 1 1 1 1 Leg1 Syja_N PF02383.18 GAX25647.1 - 0.2 10.9 0.1 1.5 8.0 0.1 2.0 1 1 1 2 2 2 0 SacI homology domain Pkinase PF00069.25 GAX25650.1 - 4.6e-30 104.9 0.0 7.7e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX25650.1 - 6e-29 101.1 0.0 1.6e-28 99.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX25650.1 - 0.00012 21.0 0.1 0.00024 20.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase DEAD PF00270.29 GAX25651.1 - 1.5e-49 168.2 0.0 2.6e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX25651.1 - 3.8e-28 98.0 0.0 3.3e-27 95.0 0.0 2.3 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX25651.1 - 7e-05 22.9 0.0 0.00021 21.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAX25651.1 - 0.00047 19.1 0.0 0.61 8.8 0.0 2.5 2 1 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 GAX25651.1 - 0.045 13.0 0.0 0.045 13.0 0.0 1.8 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 GAX25651.1 - 0.17 12.2 0.3 0.8 10.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.6 GAX25651.1 - 6.1 6.1 7.4 8.6 5.6 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pkinase PF00069.25 GAX25652.1 - 7.3e-32 110.8 0.0 9.2e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX25652.1 - 5.7e-19 68.4 0.0 8e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX25652.1 - 0.00028 20.3 0.1 0.00076 18.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX25652.1 - 0.0041 17.1 0.5 0.04 13.8 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX25652.1 - 0.008 15.0 0.0 0.0098 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAX25652.1 - 0.037 13.0 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_M24 PF00557.24 GAX25653.1 - 1.9e-47 161.7 0.0 2.6e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 tRNA-synt_1e PF01406.19 GAX25654.1 - 8.1e-96 320.9 0.2 1.2e-95 320.3 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAX25654.1 - 3.2e-12 45.9 0.5 2.2e-07 30.0 0.3 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 GAX25654.1 - 1.1e-06 29.1 0.2 3.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.18 GAX25654.1 - 2.8e-06 26.5 0.1 0.019 13.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 GAX25654.1 - 0.00019 19.8 0.1 0.0015 16.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DUF2540 PF10802.8 GAX25654.1 - 0.096 12.8 0.2 0.36 11.0 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) MIT PF04212.18 GAX25655.1 - 0.01 15.9 0.3 0.076 13.1 0.0 2.7 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain ATG16 PF08614.11 GAX25656.1 - 0.014 15.7 13.2 0.014 15.7 13.2 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Bcr-Abl_Oligo PF09036.10 GAX25656.1 - 0.048 13.7 4.2 0.27 11.3 0.8 3.1 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain HOOK PF05622.12 GAX25656.1 - 0.076 11.2 14.6 0.13 10.4 14.6 1.3 1 0 0 1 1 1 0 HOOK protein DUF1664 PF07889.12 GAX25656.1 - 1.8 8.6 3.8 4.4 7.4 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 GAX25656.1 - 2 8.8 9.5 8 6.9 9.5 2.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 GAX25656.1 - 5.5 7.0 20.3 1.3 9.1 4.5 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Myosin_head PF00063.21 GAX25657.1 - 8.6e-66 222.5 0.0 1.4e-65 221.9 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 GAX25657.1 - 0.001 19.5 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX25657.1 - 0.0071 16.6 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX25657.1 - 0.027 14.8 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 GAX25657.1 - 0.033 13.1 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.12 GAX25657.1 - 0.039 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 GAX25657.1 - 0.058 12.4 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 GAX25657.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 GAX25657.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 GAX25657.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MCM6_C PF18263.1 GAX25658.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain DHHC PF01529.20 GAX25659.1 - 1.7e-30 105.8 16.8 1.7e-30 105.8 16.8 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Zf_RING PF16744.5 GAX25659.1 - 0.076 13.1 4.2 0.2 11.8 4.2 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Adaptin_N PF01602.20 GAX25660.1 - 1e-147 492.9 10.5 1.2e-147 492.7 10.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAX25660.1 - 2.3e-63 213.1 5.8 1.3e-62 210.6 0.0 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 GAX25660.1 - 2e-27 95.5 0.2 1.2e-26 93.0 0.0 2.3 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 GAX25660.1 - 2.8e-17 62.9 11.5 3.2e-06 27.4 0.1 5.7 3 1 2 5 5 5 5 HEAT repeats HEAT PF02985.22 GAX25660.1 - 1.2e-08 34.5 4.2 0.028 14.7 0.1 6.2 5 0 0 5 5 5 2 HEAT repeat Cnd3 PF12719.7 GAX25660.1 - 9.7e-05 21.7 1.7 0.028 13.6 0.2 3.2 2 1 2 4 4 4 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 GAX25660.1 - 0.00034 20.8 3.3 4.8 7.4 0.0 4.8 2 2 2 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 GAX25660.1 - 0.0012 18.7 1.8 0.0066 16.4 0.1 2.8 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Alpha_adaptinC2 PF02883.20 GAX25660.1 - 0.0013 19.0 1.5 0.0027 18.0 1.5 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain UNC45-central PF11701.8 GAX25660.1 - 0.0021 18.0 0.2 0.35 10.8 0.0 3.1 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 GAX25660.1 - 0.0069 16.9 7.0 40 4.9 0.0 6.0 6 0 0 6 6 6 0 HEAT-like repeat Arm_2 PF04826.13 GAX25660.1 - 0.02 14.4 0.0 0.02 14.4 0.0 3.1 4 0 0 4 4 4 0 Armadillo-like Arm PF00514.23 GAX25660.1 - 0.034 14.2 1.6 28 4.9 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 GAX25660.1 - 0.08 12.5 1.1 5.3 6.5 0.0 3.1 3 1 0 3 3 3 0 CLASP N terminal Securin PF04856.13 GAX25661.1 - 0.046 13.7 0.1 0.069 13.1 0.1 1.2 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor Lactamase_B_2 PF12706.7 GAX25662.1 - 2.6e-28 98.9 0.7 1.6e-27 96.3 0.7 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAX25662.1 - 7.7e-12 45.4 0.0 2.9e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RNA_pol_Rpb1_5 PF04998.17 GAX25664.1 - 6.5e-83 278.2 0.0 1.2e-82 277.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAX25664.1 - 2.4e-59 200.3 0.1 4.3e-59 199.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 GAX25664.1 - 1.4e-30 106.7 0.0 3.3e-30 105.5 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 GAX25664.1 - 9e-30 103.7 0.0 3.4e-29 101.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAX25664.1 - 9.1e-20 70.6 0.0 4.1e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 BUD22 PF09073.10 GAX25664.1 - 0.57 9.5 26.6 0.011 15.2 7.9 2.4 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 GAX25664.1 - 0.66 9.3 23.4 3.1 7.1 14.9 2.3 2 0 0 2 2 2 0 SDA1 PAS PF00989.25 GAX25665.1 - 0.003 17.6 0.0 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 GAX25665.1 - 0.0041 17.4 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 GAX25666.1 - 0.025 14.8 0.0 0.074 13.3 0.0 1.8 1 1 0 1 1 1 0 PAS domain BT1 PF03092.16 GAX25667.1 - 3.4e-57 193.9 8.3 6.4e-35 120.4 1.5 2.1 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 GAX25667.1 - 0.00097 18.2 0.5 0.0038 16.3 0.5 2.1 1 1 0 1 1 1 1 PUCC protein Glyco_hydro_18 PF00704.28 GAX25668.1 - 1.4e-16 61.2 0.3 2.4e-16 60.4 0.3 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Ammonium_transp PF00909.21 GAX25668.1 - 0.055 12.2 0.2 0.086 11.5 0.2 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family Flavi_NS1 PF00948.21 GAX25668.1 - 0.06 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 zf-RING_6 PF14835.6 GAX25668.1 - 0.65 9.9 2.7 3.5 7.6 0.0 2.9 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Heme_oxygenase PF01126.20 GAX25669.1 - 2.9e-59 200.3 0.1 3.3e-59 200.1 0.1 1.0 1 0 0 1 1 1 1 Heme oxygenase AcetylCoA_hyd_C PF13336.6 GAX25670.1 - 2.7e-47 160.6 0.0 4e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 GAX25670.1 - 4.2e-12 46.5 0.0 8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Acetyltransf_3 PF13302.7 GAX25670.1 - 0.12 13.1 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mal_decarbox_Al PF16957.5 GAX25670.1 - 0.23 9.8 0.0 0.35 9.2 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter IQ PF00612.27 GAX25671.1 - 0.0017 18.0 1.4 0.005 16.5 1.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif SPATA1_C PF15743.5 GAX25671.1 - 0.0041 17.2 23.0 0.021 14.9 13.2 2.3 1 1 1 2 2 2 1 Spermatogenesis-associated C-terminus CENP-F_leu_zip PF10473.9 GAX25671.1 - 0.0047 17.0 15.2 0.0047 17.0 15.2 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 GAX25671.1 - 0.0084 15.4 9.1 0.0084 15.4 9.1 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) TMPIT PF07851.13 GAX25671.1 - 0.012 14.9 3.6 0.012 14.9 3.6 2.1 2 0 0 2 2 2 0 TMPIT-like protein bZIP_1 PF00170.21 GAX25671.1 - 0.017 15.2 17.7 0.21 11.7 2.0 3.7 2 1 0 3 3 3 0 bZIP transcription factor KASH_CCD PF14662.6 GAX25671.1 - 0.13 12.0 19.4 0.27 11.0 19.4 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 GAX25671.1 - 0.15 9.5 20.3 0.2 9.1 20.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 GAX25671.1 - 0.16 11.3 23.8 3.7 6.8 3.1 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 GAX25671.1 - 0.2 12.1 24.1 0.11 13.0 7.2 3.4 1 1 2 3 3 3 0 Cell division protein ZapB SlyX PF04102.12 GAX25671.1 - 0.27 11.9 14.2 1.2 9.7 0.6 3.4 2 1 1 3 3 3 0 SlyX NRBF2 PF08961.10 GAX25671.1 - 0.31 10.6 10.4 0.19 11.3 7.7 2.0 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Peptidase_S64 PF08192.11 GAX25671.1 - 0.42 9.0 8.2 0.56 8.6 8.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Spc7 PF08317.11 GAX25671.1 - 0.58 9.0 22.3 0.018 13.9 2.1 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Wtap PF17098.5 GAX25671.1 - 0.61 10.0 14.9 5 7.0 15.0 2.4 1 1 0 1 1 1 0 WTAP/Mum2p family DUF1664 PF07889.12 GAX25671.1 - 0.66 10.0 11.5 0.24 11.4 0.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Plk4_PB2 PF18409.1 GAX25671.1 - 0.69 10.6 8.1 0.25 12.1 1.0 3.1 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 BLOC1_2 PF10046.9 GAX25671.1 - 0.8 10.0 11.1 0.35 11.2 3.8 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.10 GAX25671.1 - 0.81 10.0 13.2 4.9 7.5 5.4 2.7 2 0 0 2 2 2 0 Tup N-terminal DUF5082 PF16888.5 GAX25671.1 - 0.88 9.9 13.3 9.8 6.5 6.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 GAX25671.1 - 1 9.8 9.3 16 6.0 0.0 3.9 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 GAX25671.1 - 1.2 9.4 14.4 1.5 9.0 0.4 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Dam1 PF08653.10 GAX25671.1 - 1.3 8.9 5.1 5.1 7.0 0.6 2.7 2 1 1 3 3 2 0 DASH complex subunit Dam1 TolA_bind_tri PF16331.5 GAX25671.1 - 1.4 9.1 10.1 8.9 6.5 0.3 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF1640 PF07798.11 GAX25671.1 - 1.6 8.8 20.0 6.1 6.9 18.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Sec20 PF03908.13 GAX25671.1 - 1.9 8.4 5.8 1.6 8.7 1.2 2.8 2 1 1 3 3 3 0 Sec20 TMF_TATA_bd PF12325.8 GAX25671.1 - 1.9 8.7 18.5 0.14 12.4 10.5 2.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 GAX25671.1 - 2 8.5 14.9 2 8.4 2.1 2.7 1 1 1 2 2 2 0 Laminin Domain II HALZ PF02183.18 GAX25671.1 - 2.1 8.7 7.7 4.4 7.6 3.1 3.1 1 1 2 3 3 3 0 Homeobox associated leucine zipper DUF948 PF06103.11 GAX25671.1 - 3.2 8.1 9.4 2.8 8.2 3.9 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 GAX25671.1 - 3.3 5.5 16.9 0.45 8.4 12.9 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.11 GAX25671.1 - 3.7 7.3 19.3 15 5.4 11.6 2.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.11 GAX25671.1 - 3.8 7.7 24.9 52 4.0 24.9 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 GAX25671.1 - 3.8 7.3 22.9 0.49 10.2 6.0 3.7 2 1 2 4 4 4 0 Septum formation initiator HisKA_3 PF07730.13 GAX25671.1 - 4.1 8.0 10.1 6.7 7.3 0.3 3.7 2 1 0 2 2 2 0 Histidine kinase DUF641 PF04859.12 GAX25671.1 - 5.7 7.3 18.5 7.3 6.9 10.2 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 GAX25671.1 - 5.7 7.0 20.1 0.49 10.5 13.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 GAX25671.1 - 7 7.6 18.5 2.5 9.0 10.7 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain USP8_interact PF08941.10 GAX25671.1 - 7.4 6.3 11.2 0.27 11.0 2.5 2.5 1 1 2 3 3 3 0 USP8 interacting YabA PF06156.13 GAX25671.1 - 8.7 7.1 17.0 5.3 7.7 0.4 3.2 1 1 2 3 3 3 0 Initiation control protein YabA KxDL PF10241.9 GAX25671.1 - 9.6 6.6 13.3 0.7 10.2 0.7 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein MCR_C PF04609.12 GAX25672.1 - 0.087 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C IQ PF00612.27 GAX25673.1 - 0.007 16.1 3.2 0.016 14.9 3.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PRC2_HTH_1 PF18118.1 GAX25673.1 - 0.024 15.5 1.8 0.024 15.5 1.8 2.7 2 1 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Jnk-SapK_ap_N PF09744.9 GAX25673.1 - 0.51 10.5 21.4 0.053 13.7 11.0 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 GAX25674.1 - 0.21 11.9 12.9 0.32 11.3 2.8 2.8 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_12 PF13424.6 GAX25675.1 - 2e-26 92.1 11.1 6.6e-09 35.9 0.2 4.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25675.1 - 2e-18 65.3 14.9 1.4e-06 27.9 1.1 5.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX25675.1 - 5.1e-17 61.1 13.7 3.2e-05 23.7 0.2 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25675.1 - 2.7e-16 58.3 12.5 0.0011 18.9 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX25675.1 - 4.7e-16 57.5 12.0 1.4e-06 28.0 0.2 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25675.1 - 5.1e-14 51.2 15.7 7.1e-05 22.7 0.1 5.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX25675.1 - 1.5e-10 40.9 6.6 0.036 14.9 0.3 5.1 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX25675.1 - 2.3e-08 34.1 13.3 0.12 13.1 0.1 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX25675.1 - 1.3e-07 31.3 10.4 3.7e-05 23.3 4.8 2.8 1 1 2 3 3 3 3 MalT-like TPR region TPR_11 PF13414.6 GAX25675.1 - 2.8e-06 26.9 0.2 2.8e-06 26.9 0.2 4.1 4 2 1 5 5 5 1 TPR repeat TPR_19 PF14559.6 GAX25675.1 - 3.5e-06 27.4 6.7 0.0093 16.5 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25675.1 - 3.6e-05 24.3 5.1 0.016 15.8 0.2 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAX25675.1 - 8.8e-05 22.6 7.0 2.2 8.8 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat PPR PF01535.20 GAX25675.1 - 0.0012 18.9 2.0 1.9 8.9 0.1 3.7 3 0 0 3 3 3 1 PPR repeat TPR_4 PF07721.14 GAX25675.1 - 0.0033 17.9 0.0 19 6.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 GAX25675.1 - 0.0084 15.8 7.3 0.32 10.7 0.9 3.9 1 1 2 3 3 3 2 26S proteasome subunit RPN7 BTAD PF03704.17 GAX25675.1 - 0.0093 16.4 4.9 1.2 9.6 0.7 3.1 3 1 0 3 3 3 2 Bacterial transcriptional activator domain MIT PF04212.18 GAX25675.1 - 0.023 14.7 2.6 0.023 14.7 2.6 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Paf67 PF10255.9 GAX25675.1 - 0.046 12.7 1.7 0.062 12.3 1.3 1.4 1 1 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Mad3_BUB1_I PF08311.12 GAX25675.1 - 0.089 12.8 1.3 1.4 8.9 0.0 2.6 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_9 PF13371.6 GAX25675.1 - 0.17 12.0 2.6 2.1 8.5 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX25675.1 - 0.73 10.0 3.8 56 3.9 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DDE_5 PF13546.6 GAX25676.1 - 0.14 11.5 2.3 1.8 7.8 0.1 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease zf-MYND PF01753.18 GAX25676.1 - 1.4 9.0 15.3 0.054 13.6 7.1 2.5 2 0 0 2 2 2 0 MYND finger PXA PF02194.15 GAX25677.1 - 2.8e-21 76.3 0.0 2.3e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 PXA domain Nexin_C PF08628.12 GAX25677.1 - 4.4e-10 40.1 0.0 1.3e-09 38.7 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 GAX25677.1 - 0.00014 21.8 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 PX domain TPR_17 PF13431.6 GAX25678.1 - 0.047 14.1 0.0 2.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_21 PF13304.6 GAX25679.1 - 0.015 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TPR_14 PF13428.6 GAX25679.1 - 0.068 14.0 2.4 0.53 11.2 0.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4998 PF16389.5 GAX25680.1 - 0.012 15.2 0.9 0.017 14.7 0.5 1.5 2 0 0 2 2 2 0 Domain of unknown function Ribosomal_L4 PF00573.22 GAX25680.1 - 0.47 10.1 5.8 0.11 12.1 1.9 1.7 1 1 1 2 2 2 0 Ribosomal protein L4/L1 family CorA PF01544.18 GAX25680.1 - 0.85 8.9 9.4 1.2 8.3 9.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 GAX25680.1 - 4.8 5.0 13.5 5.8 4.7 13.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0176_N PF17773.1 GAX25682.1 - 4.3e-17 62.3 0.0 1.5e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GAX25682.1 - 2.2e-05 24.9 0.0 5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 GAX25682.1 - 0.00033 21.0 0.6 0.0011 19.3 0.6 1.9 1 1 0 1 1 1 1 Rhodanase C-terminal Peptidase_M3 PF01432.20 GAX25683.1 - 4.5e-117 392.1 3.6 6.2e-117 391.7 3.6 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF3138 PF11336.8 GAX25683.1 - 0.061 11.9 1.3 0.093 11.3 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Aa_trans PF01490.18 GAX25684.1 - 1.8e-59 201.5 12.3 2.1e-59 201.3 12.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAX25684.1 - 0.0006 19.0 1.6 0.0006 19.0 1.6 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family MerC PF03203.14 GAX25684.1 - 5.4 7.5 16.1 1.2 9.7 0.9 4.0 2 1 2 4 4 4 0 MerC mercury resistance protein Med21 PF11221.8 GAX25685.1 - 1.3e-09 38.4 3.5 1.9e-09 37.9 3.5 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Zea_mays_MuDR PF05928.11 GAX25685.1 - 0.013 15.1 1.8 0.048 13.3 0.3 2.3 1 1 1 2 2 2 0 Zea mays MURB-like protein (MuDR) Med9 PF07544.13 GAX25685.1 - 0.059 13.5 1.4 0.37 10.9 0.3 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SMAP PF15477.6 GAX25685.1 - 1.3 10.1 4.2 3.1 8.8 4.2 1.8 1 1 0 1 1 1 0 Small acidic protein family AAA_2 PF07724.14 GAX25686.1 - 3.1e-38 131.6 0.0 5e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAX25686.1 - 1.3e-10 41.8 0.0 2.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAX25686.1 - 9.1e-10 38.5 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 GAX25686.1 - 5.7e-05 23.4 0.1 0.0011 19.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 GAX25686.1 - 6.6e-05 22.1 0.0 0.00016 20.9 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 GAX25686.1 - 0.0017 18.4 0.2 0.0061 16.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 GAX25686.1 - 0.003 18.1 0.0 0.0074 16.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 GAX25686.1 - 0.0033 18.0 0.0 0.0085 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TF_Zn_Ribbon PF08271.12 GAX25686.1 - 0.0042 16.6 0.2 0.01 15.3 0.2 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Mg_chelatase PF01078.21 GAX25686.1 - 0.0056 16.1 0.0 0.027 13.9 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GAX25686.1 - 0.0061 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 GAX25686.1 - 0.0078 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 GAX25686.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 GAX25686.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Lar_restr_allev PF14354.6 GAX25686.1 - 0.017 15.5 0.9 0.039 14.3 0.9 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-TFIIB PF13453.6 GAX25686.1 - 0.047 13.0 0.5 0.13 11.6 0.5 1.8 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_7 PF12775.7 GAX25686.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 GAX25686.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Zn_Tnp_IS1595 PF12760.7 GAX25686.1 - 0.086 12.8 2.2 0.16 11.9 2.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NACHT PF05729.12 GAX25686.1 - 0.094 12.6 0.1 0.24 11.3 0.1 1.8 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 GAX25686.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 GAX25686.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain LIN37 PF15306.6 GAX25686.1 - 0.12 12.6 0.5 0.23 11.6 0.5 1.4 1 0 0 1 1 1 0 LIN37 Sigma54_activat PF00158.26 GAX25686.1 - 0.13 12.0 0.0 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Cir_N PF10197.9 GAX25686.1 - 0.55 10.5 3.0 1.4 9.1 3.0 1.7 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Phage_Coat_B PF05356.11 GAX25688.1 - 0.013 15.4 0.3 0.03 14.2 0.1 1.7 2 0 0 2 2 2 0 Phage Coat protein B Sod_Cu PF00080.20 GAX25688.1 - 0.13 12.5 1.7 0.72 10.0 1.7 2.0 1 1 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) Sec20 PF03908.13 GAX25689.1 - 0.14 12.0 0.3 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Sec20 zf-SCNM1 PF15803.5 GAX25690.1 - 0.29 10.8 1.8 1.5 8.5 0.4 2.3 1 1 1 2 2 2 0 Zinc-finger of sodium channel modifier 1 Carboxyl_trans PF01039.22 GAX25691.1 - 3.2e-143 478.0 0.0 4.2e-143 477.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 GAX25691.1 - 0.0069 15.7 0.1 0.031 13.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase PK PF00224.21 GAX25694.1 - 1.5e-139 464.8 0.3 2e-139 464.3 0.3 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAX25694.1 - 1.7e-19 70.1 0.4 5.7e-19 68.5 0.3 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAX25694.1 - 0.0026 17.0 0.3 0.007 15.5 0.2 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Methyltransf_23 PF13489.6 GAX25695.1 - 0.00036 20.4 0.1 0.00073 19.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAX25695.1 - 0.19 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ank_2 PF12796.7 GAX25696.1 - 8.2e-08 32.7 0.1 0.0068 17.0 0.0 4.8 2 2 4 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX25696.1 - 2e-06 28.2 0.1 0.39 11.4 0.0 5.1 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX25696.1 - 5.6e-05 23.4 0.4 13 6.4 0.2 4.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 GAX25696.1 - 0.00048 20.4 0.1 22 6.0 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat HEAT_EZ PF13513.6 GAX25696.1 - 0.007 16.9 2.7 6.5 7.4 0.0 3.8 3 1 1 4 4 4 2 HEAT-like repeat Ank_5 PF13857.6 GAX25696.1 - 0.048 14.0 0.8 43 4.6 0.0 4.3 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Arm PF00514.23 GAX25696.1 - 0.066 13.3 2.4 11 6.2 0.1 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat XPG_I PF00867.18 GAX25697.1 - 4.6e-25 87.8 1.4 1.9e-24 85.8 0.0 2.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 GAX25697.1 - 5.6e-21 74.9 0.0 1.3e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_100 PF12899.7 GAX25697.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Alkaline and neutral invertase Tfb4 PF03850.14 GAX25698.1 - 0.22 11.0 1.2 0.4 10.1 1.0 1.5 1 1 0 1 1 1 0 Transcription factor Tfb4 Spond_N PF06468.13 GAX25699.1 - 7.9e-25 88.1 0.0 9.8e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Spondin_N PEGSRP PF07623.11 GAX25699.1 - 0.047 13.5 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Metallophos PF00149.28 GAX25700.1 - 4.9e-14 53.3 4.0 1.2e-13 52.0 4.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAX25700.1 - 2.2e-12 47.6 3.0 1.3e-11 45.1 0.1 3.1 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAX25700.1 - 1.5e-07 31.9 1.7 5.8e-07 30.0 1.7 2.1 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PEPcase PF00311.17 GAX25701.1 - 1.8e-252 840.0 0.9 2.7e-251 836.1 0.2 2.0 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GAX25701.1 - 3.9e-06 25.6 0.0 8.3e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Methyltransf_16 PF10294.9 GAX25702.1 - 1.6e-25 89.9 0.1 1.9e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX25702.1 - 2.9e-07 30.2 0.2 4.1e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAX25702.1 - 0.00026 20.8 0.1 0.00037 20.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX25702.1 - 0.00037 21.1 0.1 0.0007 20.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX25702.1 - 0.00071 19.1 0.1 0.00095 18.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 GAX25702.1 - 0.00094 19.9 0.0 0.0016 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX25702.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX25702.1 - 0.0034 17.2 0.1 0.0045 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAX25702.1 - 0.012 14.9 0.5 0.079 12.2 0.5 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 GAX25702.1 - 0.028 15.1 0.1 0.047 14.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 GAX25702.1 - 0.033 13.5 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cons_hypoth95 PF03602.15 GAX25702.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HSF_DNA-bind PF00447.17 GAX25704.1 - 9.5e-20 71.0 0.1 1.6e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding VWD PF00094.25 GAX25705.1 - 0.009 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain RGM_C PF06534.13 GAX25705.1 - 0.019 14.5 0.1 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus F-box PF00646.33 GAX25706.1 - 0.0078 16.1 0.2 0.02 14.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAX25706.1 - 0.015 15.2 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 F-box-like UNC-93 PF05978.16 GAX25707.1 - 7.8e-13 48.4 5.6 7.8e-13 48.4 5.6 2.8 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 GAX25707.1 - 2e-11 43.4 27.0 3e-11 42.9 24.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily IMP2_N PF18590.1 GAX25708.1 - 8.9e-22 77.5 0.0 1.3e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 GAX25708.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) C-terminal domain Gypsy PF07253.11 GAX25709.1 - 0.1 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein FmrO PF07091.11 GAX25710.1 - 0.055 13.0 0.8 0.074 12.6 0.8 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RIX1 PF08167.12 GAX25710.1 - 0.088 12.5 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis CDI PF02234.19 GAX25713.1 - 0.27 11.4 2.3 0.66 10.2 2.3 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor DUF5527 PF17665.1 GAX25713.1 - 7.4 6.1 9.0 0.74 9.4 0.7 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5527) Glyco_transf_25 PF01755.17 GAX25714.1 - 5.2e-05 23.2 8.6 0.024 14.5 0.1 4.2 3 2 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-SNAP50_C PF12251.8 GAX25714.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Mur_ligase_M PF08245.12 GAX25715.1 - 3e-06 27.3 0.0 1.6e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Sulfotransfer_4 PF17784.1 GAX25716.1 - 1.1e-50 172.4 0.1 1.6e-50 171.9 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX25716.1 - 0.0002 21.8 0.0 0.033 14.6 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family DUF3377 PF11857.8 GAX25716.1 - 0.09 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) GrpE PF01025.19 GAX25717.1 - 2.4e-48 164.0 7.5 3.2e-48 163.5 7.5 1.2 1 0 0 1 1 1 1 GrpE eIF3g PF12353.8 GAX25717.1 - 0.075 13.4 3.3 0.092 13.1 2.0 1.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G EF-hand_7 PF13499.6 GAX25718.1 - 2.5e-34 117.5 14.8 1.9e-15 57.1 3.3 2.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAX25718.1 - 3.7e-32 107.5 17.6 1.7e-08 33.4 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GAX25718.1 - 9.4e-27 90.6 12.6 8.3e-08 31.6 0.3 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAX25718.1 - 6.7e-25 85.4 16.5 2.9e-06 26.5 1.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAX25718.1 - 3.2e-22 78.1 16.8 4.9e-12 45.5 2.8 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 GAX25718.1 - 6.8e-10 39.1 1.6 1.2e-05 25.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAX25718.1 - 3.6e-07 30.5 1.2 0.012 16.0 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAX25718.1 - 7.2e-07 29.1 7.6 0.018 15.0 0.2 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 GAX25718.1 - 1.3e-06 29.2 0.1 0.016 16.1 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain DUF3349 PF11829.8 GAX25718.1 - 0.00027 21.7 0.2 0.26 12.1 0.1 2.4 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 GAX25718.1 - 0.00043 20.4 1.8 0.67 10.2 0.1 3.6 1 1 3 4 4 4 2 Dockerin type I domain DUF2267 PF10025.9 GAX25718.1 - 0.0028 17.9 0.0 0.0087 16.3 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) FGAR-AT_linker PF18072.1 GAX25718.1 - 0.026 15.1 1.4 12 6.6 0.0 3.3 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain RNA_pol_Rpb4 PF03874.16 GAX25718.1 - 0.051 13.9 1.0 0.6 10.5 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 UPF0154 PF03672.13 GAX25718.1 - 0.12 12.5 0.0 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF533 PF04391.12 GAX25718.1 - 0.15 11.6 4.2 0.47 10.0 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF533) SapB_1 PF05184.15 GAX25718.1 - 0.27 11.3 2.5 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 Cation_efflux PF01545.21 GAX25719.1 - 6e-37 127.3 20.7 1.3e-36 126.3 20.7 1.5 1 1 0 1 1 1 1 Cation efflux family Vac7 PF12751.7 GAX25719.1 - 0.0011 18.6 7.9 0.0017 17.9 7.9 1.3 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 EVI2A PF05399.11 GAX25719.1 - 0.74 9.4 7.8 1.5 8.3 7.7 1.6 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF4834 PF16118.5 GAX25719.1 - 3.8 8.5 6.5 24 6.0 6.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) AA_permease_2 PF13520.6 GAX25720.1 - 0.0088 14.9 2.4 0.011 14.6 2.4 1.1 1 0 0 1 1 1 1 Amino acid permease ECF_trnsprt PF12822.7 GAX25720.1 - 0.19 11.9 5.1 0.26 11.4 5.1 1.2 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Corona_NS3b PF03053.14 GAX25720.1 - 0.37 10.5 2.6 0.39 10.5 0.9 1.7 1 1 1 2 2 2 0 ORF3b coronavirus protein DUF383 PF04063.14 GAX25721.1 - 1.2e-34 119.7 0.0 2.3e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 GAX25721.1 - 7e-10 38.6 0.7 4.1e-09 36.1 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Ribosomal_S5 PF00333.20 GAX25722.1 - 4.9e-26 90.5 0.3 1.1e-25 89.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GAX25722.1 - 8.4e-24 82.8 0.0 1.6e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 GAX25722.1 - 2.3 8.8 19.2 4.8 7.8 19.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RabGAP-TBC PF00566.18 GAX25723.1 - 6.8e-12 45.5 1.3 6.8e-12 45.5 1.3 3.3 1 1 0 2 2 2 1 Rab-GTPase-TBC domain SKG6 PF08693.10 GAX25723.1 - 0.062 12.7 2.5 0.19 11.2 2.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Secretin_N_2 PF07655.13 GAX25723.1 - 2.2 8.8 23.1 4.8 7.8 23.1 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain NPR3 PF03666.13 GAX25723.1 - 3.4 6.3 13.2 10 4.8 13.2 1.8 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_U32 PF01136.19 GAX25725.1 - 9.7e-83 276.9 0.0 6e-71 238.3 0.0 2.7 2 1 0 2 2 2 2 Peptidase family U32 DUF3656 PF12392.8 GAX25725.1 - 2.7e-16 60.1 0.1 2.7e-16 60.1 0.1 2.1 2 0 0 2 2 2 1 Collagenase BTB_2 PF02214.22 GAX25726.1 - 1.2e-19 70.5 0.0 2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX25726.1 - 3.6e-05 23.8 0.0 8.1e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX25727.1 - 1.2e-17 64.1 0.1 3.3e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX25727.1 - 4.2e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX25728.1 - 1.8e-13 50.6 0.0 3.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX25728.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 GAX25729.1 - 9.2e-19 67.6 0.0 2.5e-18 66.2 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 GAX25729.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 GAX25730.1 - 4.8e-18 65.3 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX25730.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX25731.1 - 1.6e-17 63.6 0.0 2.9e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAX25731.1 - 0.09 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 GAX25732.1 - 1.8e-15 57.1 0.0 3.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain LRR_4 PF12799.7 GAX25733.1 - 4.9e-26 90.4 17.0 9.6e-06 25.9 0.1 6.5 6 1 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX25733.1 - 7e-21 73.8 28.9 1.9e-07 30.8 0.3 6.9 3 2 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 GAX25733.1 - 3e-10 39.2 18.9 1 10.2 0.1 10.4 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX25733.1 - 0.034 14.2 19.5 20 5.5 0.1 8.9 10 0 0 10 10 10 0 Leucine Rich repeat LRR_9 PF14580.6 GAX25733.1 - 0.049 13.1 1.1 2.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeat Spo7_2_N PF15407.6 GAX25733.1 - 0.071 12.8 0.0 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 adh_short PF00106.25 GAX25734.1 - 3e-24 85.6 0.0 4.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX25734.1 - 1.3e-10 41.2 0.0 2.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NOG1_N PF17835.1 GAX25734.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Macoilin PF09726.9 GAX25736.1 - 2.9e-05 22.9 1.8 2.9e-05 22.9 1.8 2.1 2 0 0 2 2 2 1 Macoilin family PSD1 PF07587.11 GAX25736.1 - 7.9e-05 22.3 1.8 0.0001 21.9 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1553) Tropomyosin_1 PF12718.7 GAX25736.1 - 0.014 15.6 5.2 0.022 14.9 5.2 1.4 1 0 0 1 1 1 0 Tropomyosin like Cob_adeno_trans PF01923.18 GAX25736.1 - 0.047 13.8 1.4 0.1 12.7 1.2 1.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Syntaxin-6_N PF09177.11 GAX25736.1 - 0.073 13.6 4.4 0.37 11.4 4.1 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CLZ PF16526.5 GAX25736.1 - 0.13 12.7 9.4 0.42 11.0 0.9 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lys-AminoMut_A PF09043.11 GAX25736.1 - 0.13 10.7 1.4 0.17 10.3 1.4 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit DUF724 PF05266.14 GAX25736.1 - 0.14 11.9 3.7 0.26 11.1 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1978 PF09321.10 GAX25736.1 - 0.16 11.2 9.3 1.3 8.3 9.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) Fib_alpha PF08702.10 GAX25736.1 - 0.37 11.0 5.3 0.84 9.8 3.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Bcr-Abl_Oligo PF09036.10 GAX25736.1 - 0.79 9.8 6.1 0.7 9.9 0.5 2.2 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Enkurin PF13864.6 GAX25736.1 - 2 8.9 7.8 1.2 9.7 5.2 1.9 1 1 1 2 2 2 0 Calmodulin-binding SARAF PF06682.12 GAX25736.1 - 4.9 6.7 15.6 7.7 6.1 15.6 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis zf-C4H2 PF10146.9 GAX25736.1 - 7.4 6.8 9.6 17 5.7 9.6 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein DnaJ PF00226.31 GAX25737.1 - 1.2e-15 57.4 0.1 3e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Macoilin PF09726.9 GAX25737.1 - 7.2e-05 21.6 11.4 7.2e-05 21.6 11.4 2.3 2 1 0 2 2 2 1 Macoilin family PSD1 PF07587.11 GAX25737.1 - 0.0013 18.2 2.1 0.0013 18.2 2.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1553) Cob_adeno_trans PF01923.18 GAX25737.1 - 0.092 12.9 1.4 0.27 11.4 1.2 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase CLZ PF16526.5 GAX25737.1 - 1 9.7 11.8 0.86 10.0 0.9 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 GAX25737.1 - 1.7 8.8 6.1 5 7.3 4.2 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Bcr-Abl_Oligo PF09036.10 GAX25737.1 - 2.1 8.4 5.8 1.5 8.9 0.6 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF1978 PF09321.10 GAX25737.1 - 2.5 7.4 11.9 2.7 7.2 8.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1978) Tropomyosin_1 PF12718.7 GAX25737.1 - 3.7 7.7 12.5 0.17 12.1 6.5 1.9 2 0 0 2 2 2 0 Tropomyosin like PNP_UDP_1 PF01048.20 GAX25738.1 - 4e-21 75.3 0.1 4.9e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Hydrolase_6 PF13344.6 GAX25739.1 - 6.7e-26 90.4 0.0 1.4e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX25739.1 - 3.4e-15 55.9 0.0 7.5e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 GAX25739.1 - 6.5e-07 29.6 0.0 0.012 15.8 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX25739.1 - 1.5e-06 28.7 0.0 3.7e-05 24.1 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAX25739.1 - 0.0019 17.8 0.2 0.21 11.2 0.1 2.5 3 0 0 3 3 3 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 GAX25739.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DSPc PF00782.20 GAX25740.1 - 4.1e-08 33.1 0.0 6.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX25740.1 - 0.00053 19.6 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAX25740.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate AEP1 PF17049.5 GAX25740.1 - 0.18 10.8 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 Lon_C PF05362.13 GAX25741.1 - 0.082 12.4 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain LRR_8 PF13855.6 GAX25743.1 - 1.9e-24 85.2 36.6 1.1e-06 28.3 5.7 6.6 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAX25743.1 - 1.2e-20 73.3 34.8 6.2e-05 23.3 1.7 8.5 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX25743.1 - 8.9e-08 31.7 24.0 0.63 10.8 0.0 9.6 9 2 0 9 9 9 3 Leucine Rich Repeat TMEM51 PF15345.6 GAX25743.1 - 0.084 12.7 0.1 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 Phage_tube PF04985.14 GAX25743.1 - 0.14 11.9 0.0 0.86 9.3 0.0 2.2 2 0 0 2 2 2 0 Phage tail tube protein FII Amidase PF01425.21 GAX25744.1 - 5.1e-96 322.4 1.6 1.8e-74 251.4 1.0 2.2 2 0 0 2 2 2 2 Amidase Trigger_C PF05698.14 GAX25744.1 - 0.024 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Ldh_2 PF02615.14 GAX25745.1 - 5.7e-83 278.8 6.3 6.6e-83 278.6 6.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PCNA_C PF02747.15 GAX25746.1 - 1.5e-50 170.7 0.1 9.4e-50 168.1 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 GAX25746.1 - 3.7e-42 143.0 4.9 7.1e-42 142.1 4.9 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 GAX25746.1 - 6.8e-07 29.0 0.1 7.8e-07 28.8 0.1 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 GAX25746.1 - 7.4e-05 21.9 1.0 0.00013 21.1 1.0 1.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CRAL_TRIO PF00650.20 GAX25747.1 - 1.5e-18 67.0 0.0 3.1e-18 66.0 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX25747.1 - 0.16 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2358 PF10184.9 GAX25748.1 - 7.2e-07 29.5 0.0 1.7e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) PAP_fibrillin PF04755.12 GAX25748.1 - 4.6e-05 23.5 0.0 0.2 11.6 0.0 2.3 1 1 0 2 2 2 2 PAP_fibrillin AGH PF17558.2 GAX25749.1 - 0.0064 16.7 0.7 0.0099 16.0 0.2 1.6 2 0 0 2 2 2 1 Androgenic gland hormone MRG PF05712.13 GAX25750.1 - 1.3e-18 67.1 3.3 5.5e-18 65.0 0.1 2.6 2 1 0 2 2 2 1 MRG Tudor-knot PF11717.8 GAX25750.1 - 5.1e-10 39.1 0.7 1.2e-09 37.9 0.7 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Tudor_FRX1 PF18336.1 GAX25750.1 - 0.044 13.7 0.1 9 6.3 0.1 2.6 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain DnaJ PF00226.31 GAX25752.1 - 9.6e-24 83.3 0.2 2.1e-23 82.2 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 GAX25752.1 - 2.9e-13 50.0 3.3 5.9e-13 49.0 3.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 GAX25752.1 - 2.4e-05 24.1 0.0 8.3e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25752.1 - 4.6e-05 23.0 0.1 0.00025 20.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX25752.1 - 0.022 15.0 0.0 0.068 13.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat RPA_C PF08784.11 GAX25752.1 - 0.037 14.7 1.3 0.098 13.3 1.3 1.7 1 0 0 1 1 1 0 Replication protein A C terminal TPR_14 PF13428.6 GAX25752.1 - 0.056 14.3 0.4 0.36 11.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25752.1 - 0.086 12.9 0.0 0.32 11.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX25752.1 - 0.094 13.2 0.2 0.38 11.3 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec3_C PF09763.9 GAX25754.1 - 2e-26 92.6 2.6 2.2e-19 69.3 0.0 2.7 2 1 0 2 2 2 2 Exocyst complex component Sec3 Bac_rhamnosid6H PF17389.2 GAX25755.1 - 0.0098 15.2 0.6 0.014 14.6 0.6 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain CCDC53 PF10152.9 GAX25756.1 - 3.1e-33 115.4 43.0 1.1e-05 25.8 1.5 9.7 8 1 1 9 9 9 7 Subunit CCDC53 of WASH complex Peptidase_S8_N PF16361.5 GAX25756.1 - 0.0032 18.0 1.2 0.016 15.7 1.2 2.3 1 0 0 1 1 1 1 N-terminal of Subtilase family Ribosomal_L24e PF01246.20 GAX25756.1 - 0.015 15.5 2.8 17 5.7 0.0 5.4 6 0 0 6 6 6 0 Ribosomal protein L24e IGR PF09597.10 GAX25756.1 - 0.029 14.5 0.5 16 5.7 0.0 3.8 3 0 0 3 3 3 0 IGR protein motif Ribosomal_S21e PF01249.18 GAX25756.1 - 0.14 12.3 0.6 20 5.4 0.0 3.3 4 0 0 4 4 4 0 Ribosomal protein S21e Toprim_2 PF13155.6 GAX25756.1 - 0.87 10.1 3.6 2.3 8.7 0.1 3.3 3 0 0 3 3 3 0 Toprim-like PilJ PF13675.6 GAX25756.1 - 2 8.5 9.0 8.2 6.5 1.4 4.2 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cupin_8 PF13621.6 GAX25757.1 - 5.3e-41 141.0 0.0 8.6e-41 140.3 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX25757.1 - 0.0017 17.9 1.0 1.3 8.4 0.1 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Astro_capsid_p PF12226.8 GAX25757.1 - 0.65 9.1 3.8 1 8.4 3.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pyr_redox_2 PF07992.14 GAX25758.1 - 1.7e-37 129.2 0.0 2.9e-37 128.5 0.0 1.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX25758.1 - 5e-18 65.4 0.0 1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX25758.1 - 1.4e-11 44.7 0.0 1.7e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX25758.1 - 1.9e-07 30.8 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX25758.1 - 3.6e-06 26.3 0.1 6.8e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAX25758.1 - 5.4e-06 26.6 3.2 9.2e-06 25.8 0.2 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAX25758.1 - 3.2e-05 22.8 0.1 0.00011 21.1 0.3 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 GAX25758.1 - 6.4e-05 22.7 0.0 0.00017 21.3 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAX25758.1 - 0.00034 20.0 0.5 0.0013 18.1 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAX25758.1 - 0.00083 18.7 0.0 1.5 8.0 0.7 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX25758.1 - 0.0012 18.0 0.3 0.012 14.7 1.2 2.1 2 1 1 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.6 GAX25758.1 - 0.024 13.8 0.0 0.093 11.9 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GAX25758.1 - 0.032 13.5 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 GAX25758.1 - 0.062 12.3 0.6 1.1 8.3 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAX25758.1 - 0.2 10.9 0.4 11 5.1 0.1 2.5 2 0 0 2 2 2 0 FAD binding domain SCAB-ABD PF16711.5 GAX25758.1 - 2.2 8.2 4.6 0.77 9.7 0.1 2.5 3 0 0 3 3 2 0 Actin-binding domain of plant-specific actin-binding protein UAA PF08449.11 GAX25759.1 - 3.5e-44 151.2 10.2 5e-44 150.7 10.2 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 GAX25759.1 - 1.3e-05 24.7 8.9 2e-05 24.1 8.9 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 GAX25759.1 - 0.00026 20.3 1.3 0.00026 20.3 1.3 2.3 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport EamA PF00892.20 GAX25759.1 - 0.026 14.7 0.5 0.026 14.7 0.5 3.2 4 0 0 4 4 4 0 EamA-like transporter family DUF1295 PF06966.12 GAX25760.1 - 1.9e-28 99.6 6.6 2.9e-28 99.0 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 GAX25760.1 - 0.029 14.3 0.5 0.029 14.3 0.5 2.0 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1345 PF07077.11 GAX25760.1 - 0.06 13.1 4.7 0.33 10.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DHHC PF01529.20 GAX25761.1 - 1.5e-30 106.0 11.9 1.5e-30 106.0 11.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Dus PF01207.17 GAX25762.1 - 1.8e-64 217.8 0.0 2.5e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 GAX25762.1 - 9.1e-06 25.1 0.0 2.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase ATP-synt_ab PF00006.25 GAX25763.1 - 8.1e-62 208.6 0.0 1.2e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAX25763.1 - 4.3e-24 84.8 1.4 9.3e-24 83.7 1.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.6 GAX25763.1 - 0.061 13.7 0.5 0.18 12.1 0.2 1.9 2 0 0 2 2 2 0 AAA domain RnfC_N PF13375.6 GAX25763.1 - 0.063 13.2 0.5 0.21 11.5 0.1 2.1 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain NB-ARC PF00931.22 GAX25763.1 - 0.084 12.0 0.4 0.21 10.8 0.2 1.7 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 GAX25763.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 GAX25763.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 GAX25763.1 - 0.27 10.4 0.2 0.44 9.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP-synt_DE_N PF02823.16 GAX25764.1 - 3.2e-14 52.6 0.0 4.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain WD40 PF00400.32 GAX25765.1 - 1.8e-20 72.9 20.8 1e-05 26.1 0.3 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25765.1 - 1.2e-05 25.5 2.5 2.9 8.3 0.0 5.1 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 GAX25765.1 - 0.0031 17.8 28.8 0.0041 17.4 28.0 1.6 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) GIT_CC PF16559.5 GAX25765.1 - 0.018 14.9 21.6 2 8.3 1.5 4.5 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lebercilin PF15619.6 GAX25765.1 - 0.025 14.3 27.2 0.59 9.8 15.2 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TSC22 PF01166.18 GAX25765.1 - 0.038 14.3 12.5 0.039 14.2 2.4 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family HALZ PF02183.18 GAX25765.1 - 0.038 14.2 7.9 0.11 12.8 0.7 3.6 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF3138 PF11336.8 GAX25765.1 - 0.066 11.8 1.9 0.16 10.6 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4407 PF14362.6 GAX25765.1 - 0.46 9.8 22.0 0.11 11.9 9.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GCN5L1 PF06320.13 GAX25765.1 - 0.52 10.5 18.7 2.2 8.5 4.3 2.6 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) ApoO PF09769.9 GAX25765.1 - 0.74 9.8 4.8 1.4 8.9 0.5 2.3 2 0 0 2 2 2 0 Apolipoprotein O CT_C_D PF02682.16 GAX25765.1 - 0.98 9.1 2.5 1.5 8.5 1.4 1.8 1 1 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D FlaC_arch PF05377.11 GAX25765.1 - 2 8.9 8.6 7 7.1 1.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 GAX25765.1 - 2.2 9.0 23.0 0.18 12.4 6.5 3.3 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 GAX25765.1 - 3.3 8.1 25.6 1.2 9.5 6.4 2.2 1 1 1 2 2 2 0 Fez1 PRKG1_interact PF15898.5 GAX25765.1 - 3.5 8.6 23.7 6.9 7.6 9.9 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Bestrophin PF01062.21 GAX25766.1 - 3.9e-20 72.4 0.2 7.1e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GSAP-16 PF14959.6 GAX25766.1 - 0.0046 16.8 0.9 0.012 15.5 0.9 1.6 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term TMEM220 PF15071.6 GAX25766.1 - 0.042 14.6 1.6 0.077 13.8 0.1 2.2 3 0 0 3 3 3 0 Transmembrane family 220, helix IPPT PF01715.17 GAX25767.1 - 1.5e-46 159.1 0.1 3e-33 115.5 0.0 2.6 3 0 0 3 3 3 2 IPP transferase IPT PF01745.16 GAX25767.1 - 1.2e-07 31.4 1.8 2.5e-07 30.3 0.0 2.2 3 0 0 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.6 GAX25767.1 - 0.0047 17.1 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX25767.1 - 0.034 14.5 0.0 0.099 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 GAX25767.1 - 0.11 12.9 0.1 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bestrophin PF01062.21 GAX25768.1 - 3.1e-16 59.6 3.7 1.2e-07 31.4 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel KilA-N PF04383.13 GAX25768.1 - 0.2 11.5 1.0 0.36 10.7 1.0 1.3 1 0 0 1 1 1 0 KilA-N domain Isochorismatase PF00857.20 GAX25769.1 - 7.8e-40 136.9 0.0 9.5e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Globin PF00042.22 GAX25770.1 - 1.2e-05 25.8 0.0 2.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Globin Rsbr_N PF08678.10 GAX25770.1 - 0.04 14.0 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Rsbr N terminal Mtr2 PF10429.9 GAX25770.1 - 0.071 13.1 0.1 11 5.9 0.0 2.1 1 1 1 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 VPS9 PF02204.18 GAX25771.1 - 1.3e-15 57.4 0.0 3.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Mannosyl_trans PF05007.13 GAX25772.1 - 1.8e-56 191.9 19.4 2.6e-56 191.4 19.4 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 GAX25772.1 - 5.4e-12 45.4 21.4 2.2e-11 43.5 21.1 1.9 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U ArnB_C PF18677.1 GAX25774.1 - 0.087 12.9 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain LETM1 PF07766.13 GAX25775.1 - 1e-16 61.1 0.2 1e-16 61.1 0.2 1.9 2 0 0 2 2 2 1 LETM1-like protein T6SS_VipA PF05591.12 GAX25775.1 - 0.00079 19.3 1.5 0.49 10.2 0.1 3.2 4 0 0 4 4 4 2 Type VI secretion system, VipA, VC_A0107 or Hcp2 Bee_toxin PF17454.2 GAX25776.1 - 0.044 13.8 0.3 0.18 11.9 0.3 2.1 1 0 0 1 1 1 0 Honey bee toxin Ribosomal_S17_N PF16205.5 GAX25777.1 - 6.9e-31 106.5 0.1 1.4e-30 105.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 GAX25777.1 - 3.7e-27 94.2 0.5 7.4e-27 93.3 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 S1 PF00575.23 GAX25778.1 - 2.7e-30 104.5 0.4 9.1e-17 61.2 0.1 3.4 3 0 0 3 3 3 3 S1 RNA binding domain Erythro-docking PF09277.11 GAX25778.1 - 2.5 8.1 4.8 83 3.2 0.0 3.5 3 0 0 3 3 3 0 Erythronolide synthase, docking bZIP_1 PF00170.21 GAX25780.1 - 9.5e-05 22.4 9.0 0.00019 21.4 9.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor JAKMIP_CC3 PF16034.5 GAX25780.1 - 0.0084 16.1 3.4 0.011 15.7 3.4 1.2 1 0 0 1 1 1 1 JAKMIP CC3 domain TPR_MLP1_2 PF07926.12 GAX25780.1 - 0.011 15.8 12.0 0.014 15.4 12.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 GAX25780.1 - 0.013 15.6 7.7 0.013 15.6 7.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper HAUS6_N PF14661.6 GAX25780.1 - 0.056 13.0 4.0 0.073 12.6 4.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Phage_Mu_Gam PF07352.12 GAX25780.1 - 0.24 11.3 3.5 0.38 10.7 3.5 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein CCDC92 PF14916.6 GAX25780.1 - 0.29 10.9 7.2 3.6 7.4 0.2 3.1 1 1 2 3 3 3 0 Coiled-coil domain of unknown function DUF3450 PF11932.8 GAX25780.1 - 0.81 8.9 11.9 0.9 8.8 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 GAX25780.1 - 1.3 8.8 5.7 2.2 8.1 5.3 1.6 1 1 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 GAX25780.1 - 1.5 9.3 7.9 0.48 10.9 4.8 1.8 2 0 0 2 2 2 0 Cell division protein ZapB NBP1 PF08537.10 GAX25780.1 - 3 7.1 10.4 0.41 10.0 6.2 1.5 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 SOAR PF16533.5 GAX25780.1 - 5.7 7.0 7.9 1.2 9.1 1.0 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region Beach PF02138.18 GAX25783.1 - 1e-109 366.2 0.0 1.5e-109 365.7 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAX25783.1 - 3.3e-09 36.8 0.1 1.2e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH IRK_C PF17655.1 GAX25784.1 - 2.1e-09 37.2 0.1 0.0032 17.1 0.0 2.7 2 1 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 GAX25784.1 - 0.00012 21.9 9.3 0.0003 20.6 9.3 1.6 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain zf-C2H2_4 PF13894.6 GAX25784.1 - 0.11 13.3 0.5 0.45 11.5 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Ion_trans_2 PF07885.16 GAX25784.1 - 0.63 10.0 7.0 1.1 9.3 5.8 2.0 1 1 0 1 1 1 0 Ion channel RrnaAD PF00398.20 GAX25785.1 - 2.6e-35 121.8 0.1 3.3e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PH PF00169.29 GAX25786.1 - 1.3e-06 28.8 0.7 0.041 14.4 0.0 3.7 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 GAX25786.1 - 0.1 13.0 0.1 0.1 13.0 0.1 3.2 3 1 0 3 3 3 0 Pleckstrin homology domain HisKA_3 PF07730.13 GAX25786.1 - 0.28 11.7 7.2 2.3 8.8 0.4 3.1 2 0 0 2 2 2 0 Histidine kinase FapA PF03961.13 GAX25786.1 - 0.77 8.3 22.3 0.088 11.4 11.1 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A Phage_holin_4_1 PF05105.12 GAX25787.1 - 0.035 14.2 0.6 0.055 13.6 0.6 1.3 1 1 0 1 1 1 0 Bacteriophage holin family E1-E2_ATPase PF00122.20 GAX25788.1 - 2.7e-16 59.6 0.0 8.8e-16 57.9 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAX25788.1 - 2.1e-13 51.0 13.3 2.1e-07 31.5 2.2 4.1 4 1 0 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX25788.1 - 7.1e-08 32.0 0.1 1.7e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX25788.1 - 0.041 13.6 5.2 2.4 7.8 0.1 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase SPOUT_MTase PF02590.17 GAX25788.1 - 0.85 9.6 4.2 2.6 8.0 4.2 1.8 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase F-box-like PF12937.7 GAX25789.1 - 5.5e-07 29.4 1.7 6.6e-07 29.1 0.5 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAX25789.1 - 8.5e-07 28.7 0.1 1.6e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain USP19_linker PF16602.5 GAX25789.1 - 0.17 12.4 0.1 0.3 11.7 0.1 1.3 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase Laminin_G_3 PF13385.6 GAX25790.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF3245 PF11595.8 GAX25790.1 - 0.22 12.0 3.2 1.9 9.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF3835 PF12927.7 GAX25790.1 - 4.3 8.3 6.5 0.66 10.9 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) Mito_carr PF00153.27 GAX25791.1 - 9.6e-33 112.0 8.7 1.1e-13 51.0 0.8 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Cpn60_TCP1 PF00118.24 GAX25792.1 - 2.9e-143 478.1 14.5 3.2e-143 477.9 14.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MitMem_reg PF13012.6 GAX25793.1 - 2e-19 70.1 0.3 4.2e-19 69.0 0.2 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAX25793.1 - 2.3e-17 63.1 0.0 5.1e-17 61.9 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2009 PF09418.10 GAX25794.1 - 4.8e-157 523.7 2.8 6.8e-139 463.8 3.3 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2009) Fib_succ_major PF09603.10 GAX25794.1 - 0.066 13.9 0.9 0.12 13.0 0.2 1.9 2 1 0 2 2 2 0 Fibrobacter succinogenes major domain (Fib_succ_major) Aldo_ket_red PF00248.21 GAX25795.1 - 5.3e-61 206.4 0.0 6.3e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Kinesin PF00225.23 GAX25796.1 - 1.4e-98 329.9 4.8 1.4e-98 329.9 4.8 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAX25796.1 - 1.7e-20 73.5 0.0 1e-19 70.9 0.0 2.5 1 0 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 GAX25796.1 - 0.00023 21.5 147.2 0.061 13.6 26.3 8.8 2 1 5 8 8 8 5 Autophagy protein 16 (ATG16) IFT57 PF10498.9 GAX25796.1 - 0.001 18.1 14.8 0.001 18.1 14.8 6.0 4 2 2 6 6 6 2 Intra-flagellar transport protein 57 Spc42p PF11544.8 GAX25796.1 - 0.0051 16.8 1.2 0.0051 16.8 1.2 7.3 5 4 2 8 8 8 1 Spindle pole body component Spc42p UPF0242 PF06785.11 GAX25796.1 - 0.0069 16.5 12.1 0.0069 16.5 12.1 8.2 1 1 4 7 7 7 3 Uncharacterised protein family (UPF0242) N-terminus RTBV_P46 PF06216.11 GAX25796.1 - 3.6 6.4 7.2 0.47 9.3 0.5 2.7 3 0 0 3 3 3 0 Rice tungro bacilliform virus P46 protein Vip3A_N PF12495.8 GAX25796.1 - 7.8 6.4 12.8 2.3 8.1 0.9 3.5 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal Nup54 PF13874.6 GAX25797.1 - 0.0011 19.1 0.8 0.0015 18.7 0.8 1.3 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.12 GAX25797.1 - 0.0015 18.6 0.4 0.002 18.2 0.4 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5089 PF17002.5 GAX25797.1 - 0.0028 17.6 2.0 0.0034 17.3 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) SNARE PF05739.19 GAX25797.1 - 0.0032 17.4 4.3 0.0082 16.1 4.3 1.7 1 1 0 1 1 1 1 SNARE domain UPF0184 PF03670.13 GAX25797.1 - 0.0059 17.0 0.7 0.0059 17.0 0.7 1.9 1 1 0 2 2 2 1 Uncharacterised protein family (UPF0184) APG17 PF04108.12 GAX25797.1 - 0.0079 15.3 1.9 0.0091 15.2 1.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Snapin_Pallidin PF14712.6 GAX25797.1 - 0.0091 16.4 2.4 0.013 15.9 2.4 1.2 1 0 0 1 1 1 1 Snapin/Pallidin DUF16 PF01519.16 GAX25797.1 - 0.011 16.2 2.5 0.014 15.9 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 CREPT PF16566.5 GAX25797.1 - 0.015 15.5 1.1 0.03 14.5 1.1 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour SKA1 PF07160.12 GAX25797.1 - 0.03 14.2 0.4 0.036 13.9 0.4 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Rabaptin PF03528.15 GAX25797.1 - 0.031 13.0 0.8 0.037 12.7 0.8 1.0 1 0 0 1 1 1 0 Rabaptin XhlA PF10779.9 GAX25797.1 - 0.033 14.4 4.1 0.76 10.0 1.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA NPV_P10 PF05531.12 GAX25797.1 - 0.046 14.2 2.1 0.086 13.3 2.1 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 GAX25797.1 - 0.051 13.6 1.1 0.066 13.2 1.1 1.1 1 0 0 1 1 1 0 Laminin Domain II PMC2NT PF08066.12 GAX25797.1 - 0.061 14.0 1.1 0.075 13.7 1.1 1.2 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF4795 PF16043.5 GAX25797.1 - 0.061 12.9 3.6 0.077 12.6 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) V-SNARE_C PF12352.8 GAX25797.1 - 0.11 12.8 2.9 0.5 10.7 0.8 2.6 1 1 2 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus LXG PF04740.12 GAX25797.1 - 0.12 12.0 2.5 12 5.5 0.1 1.9 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF948 PF06103.11 GAX25797.1 - 0.18 12.1 1.9 0.51 10.6 1.9 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 GAX25797.1 - 0.2 11.7 6.0 0.043 13.9 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 GAX25797.1 - 0.57 10.5 3.6 0.79 10.0 0.7 2.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 GAX25797.1 - 2.7 8.7 5.4 26 5.5 5.4 2.1 1 1 0 1 1 1 0 SlyX 2OG-FeII_Oxy_3 PF13640.6 GAX25798.1 - 5.6e-16 59.2 0.1 1.5e-15 57.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_2 PF13532.6 GAX25798.1 - 4e-05 23.9 0.1 0.002 18.3 0.1 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX25798.1 - 0.00051 20.5 0.1 0.0096 16.4 0.0 2.7 3 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 GAX25799.1 - 2.7e-12 47.0 15.7 0.0027 18.5 0.4 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25799.1 - 5.8e-06 26.5 2.4 0.18 12.1 0.0 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Git3 PF11710.8 GAX25800.1 - 1.8e-09 37.7 5.3 5.6e-09 36.1 5.3 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 GAX25800.1 - 1.8e-06 27.3 1.7 3.6e-06 26.3 1.7 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Voltage_CLC PF00654.20 GAX25800.1 - 0.0099 15.2 1.2 0.017 14.4 1.2 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel DUF2721 PF11026.8 GAX25800.1 - 0.17 11.8 1.8 0.93 9.4 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Interferon PF00143.19 GAX25801.1 - 0.12 12.6 0.2 0.12 12.6 0.2 1.5 2 0 0 2 2 2 0 Interferon alpha/beta domain DUF4050 PF13259.6 GAX25803.1 - 0.0089 16.4 10.6 0.034 14.5 1.6 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF4050) FAD_binding_3 PF01494.19 GAX25804.1 - 1e-12 48.0 0.0 1.2e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAX25804.1 - 5.2e-07 30.1 0.3 0.00079 19.9 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAX25804.1 - 3e-05 23.4 0.5 0.0013 18.0 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX25804.1 - 0.0009 19.4 0.1 0.0025 18.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX25804.1 - 0.0023 17.1 1.9 0.0053 15.9 1.9 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAX25804.1 - 0.012 14.9 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX25804.1 - 0.017 14.0 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 GAX25804.1 - 0.019 14.6 1.0 0.025 14.2 1.0 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 GAX25804.1 - 0.038 13.6 0.5 0.15 11.7 0.5 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 GAX25804.1 - 0.039 13.2 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAX25804.1 - 0.052 12.3 0.1 0.21 10.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 GAX25804.1 - 0.079 12.0 0.2 0.13 11.3 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain DUF4520 PF15016.6 GAX25804.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) PrgI PF12666.7 GAX25804.1 - 0.18 12.6 0.0 0.29 11.9 0.0 1.3 1 0 0 1 1 1 0 PrgI family protein Mnd1 PF03962.15 GAX25805.1 - 1.4e-17 63.7 0.0 2.9e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 GAX25805.1 - 4.8e-16 58.6 0.1 1.6e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DUF919 PF06034.11 GAX25805.1 - 0.0061 16.4 1.8 0.01 15.6 0.4 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF919) T3SS_needle_F PF09392.10 GAX25805.1 - 0.13 12.5 2.0 0.39 10.9 0.3 2.6 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF GATase_4 PF13230.6 GAX25806.1 - 4.9e-19 68.3 0.3 2.2e-13 49.7 0.5 3.4 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAX25806.1 - 1.1e-12 48.3 0.0 1.9e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX25806.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Lipase_GDSL_2 PF13472.6 GAX25807.1 - 9e-18 65.3 0.0 1.5e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX25807.1 - 6.5e-09 36.1 0.0 8.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4050 PF13259.6 GAX25807.1 - 1.3 9.4 8.6 0.57 10.5 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4050) LRR_8 PF13855.6 GAX25808.1 - 0.01 15.6 4.6 0.021 14.6 0.9 2.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 GAX25808.1 - 0.029 14.9 0.7 3.7e+02 2.4 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 GAX25808.1 - 0.21 12.1 14.7 0.22 12.0 0.4 4.7 3 3 1 4 4 4 0 Leucine Rich repeats (2 copies) Class_IIIsignal PF04021.12 GAX25808.1 - 2.4 8.2 7.2 5 7.2 7.2 1.6 1 0 0 1 1 1 0 Class III signal peptide Peptidase_S8 PF00082.22 GAX25809.1 - 9.9e-43 146.5 8.4 1.8e-42 145.7 8.4 1.4 1 0 0 1 1 1 1 Subtilase family HEAT PF02985.22 GAX25810.1 - 2.9e-13 48.8 10.0 0.0033 17.6 0.1 6.3 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 GAX25810.1 - 6.3e-06 26.6 11.9 0.069 13.7 0.0 6.0 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAX25810.1 - 0.00039 21.0 0.0 0.017 15.7 0.0 2.9 2 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 GAX25810.1 - 0.00044 20.6 15.6 0.038 14.4 0.1 5.5 5 1 0 6 6 6 3 HEAT repeats CLASP_N PF12348.8 GAX25810.1 - 0.00061 19.4 2.1 3.8 7.0 0.0 3.7 3 1 1 4 4 4 2 CLASP N terminal IFRD PF05004.13 GAX25810.1 - 0.025 13.7 0.1 0.76 8.8 0.0 2.8 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) His_biosynth PF00977.21 GAX25811.1 - 1.5e-30 106.4 0.0 2e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 GAX25811.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ATG13 PF10033.9 GAX25812.1 - 1.2e-15 57.9 0.3 7e-10 39.0 0.2 2.7 1 1 1 2 2 2 2 Autophagy-related protein 13 Asp_Arg_Hydrox PF05118.15 GAX25813.1 - 1.4e-19 70.4 0.0 2.1e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase UDPGP PF01704.18 GAX25814.1 - 1.2e-120 403.0 0.0 1.5e-120 402.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 GAX25814.1 - 2.4e-32 111.5 0.0 4.4e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAX25814.1 - 5.4e-25 87.8 0.0 1.1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAX25814.1 - 7.1e-09 36.2 0.1 2.1e-08 34.7 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GAX25814.1 - 7.1e-05 22.9 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RRM_1 PF00076.22 GAX25815.1 - 9.9e-18 63.7 0.0 1.8e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.10 GAX25815.1 - 5.8 7.0 10.2 9.1 6.3 10.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal COPI_assoc PF08507.10 GAX25816.1 - 0.00015 21.8 4.3 0.00082 19.4 0.0 2.2 2 0 0 2 2 2 1 COPI associated protein DUF4131 PF13567.6 GAX25816.1 - 3.9 7.1 8.5 2.7 7.6 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Na_H_Exchanger PF00999.21 GAX25817.1 - 9.3e-42 143.2 39.9 1.2e-41 142.8 39.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MMS19_N PF14500.6 GAX25817.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II LRR_4 PF12799.7 GAX25818.1 - 4e-12 46.1 13.2 0.00025 21.4 0.1 5.7 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.6 GAX25818.1 - 4.2e-09 36.7 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 GAX25818.1 - 7.8e-09 35.4 0.1 2.2e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 GAX25818.1 - 8.3e-09 35.2 0.0 0.0002 20.9 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 GAX25818.1 - 1.6e-05 24.6 7.8 2.3 8.5 0.1 6.9 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 GAX25818.1 - 0.00011 21.9 10.6 0.021 14.6 0.0 5.6 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 GAX25818.1 - 0.1 13.2 14.2 46 5.1 0.4 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat FKBP_C PF00254.28 GAX25819.1 - 0.021 15.1 0.0 0.052 13.9 0.0 1.8 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 GAX25820.1 - 4.3e-10 39.8 0.0 6.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase VPS13_C PF16909.5 GAX25821.1 - 2e-36 125.4 1.8 1e-31 110.1 0.0 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 GAX25821.1 - 1.4e-10 41.0 0.0 6e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 GAX25821.1 - 5.7e-08 33.0 0.0 2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PDZ PF00595.24 GAX25821.1 - 0.0071 16.7 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Apt1 PF10351.9 GAX25821.1 - 0.013 14.4 0.0 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain PDZ_6 PF17820.1 GAX25821.1 - 0.015 15.1 0.0 0.05 13.5 0.0 1.9 1 0 0 1 1 1 0 PDZ domain VPS13 PF16908.5 GAX25822.1 - 5.3e-31 108.2 0.1 3.9e-28 98.8 0.0 3.0 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 GAX25822.1 - 1.6e-20 73.4 0.0 4e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 GAX25822.1 - 2.2e-16 60.0 0.4 1.8e-15 57.0 0.1 2.7 3 0 0 3 3 3 1 Repeating coiled region of VPS13 Met_10 PF02475.16 GAX25823.1 - 6.7e-46 156.6 0.0 1e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 GAX25823.1 - 0.00085 18.6 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 GAX25823.1 - 0.0074 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_N4_Mtase PF01555.18 GAX25823.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Methyltransf_25 PF13649.6 GAX25823.1 - 0.034 14.8 0.1 0.12 13.1 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 GAX25823.1 - 0.051 13.0 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 GAX25823.1 - 0.057 13.1 0.0 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Synaptobrevin PF00957.21 GAX25824.1 - 2.4e-09 36.9 5.9 2.4e-09 36.9 5.9 2.0 2 0 0 2 2 2 1 Synaptobrevin Ank_5 PF13857.6 GAX25824.1 - 7.5e-09 35.7 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX25824.1 - 7.4e-07 29.0 0.0 3.9e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAX25824.1 - 8.3e-07 29.2 0.0 3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 GAX25824.1 - 2e-06 28.3 0.0 4.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX25824.1 - 2e-06 28.2 0.2 0.0056 17.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HAUS6_N PF14661.6 GAX25824.1 - 0.21 11.1 5.7 0.38 10.3 5.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1664 PF07889.12 GAX25824.1 - 0.52 10.4 4.8 1.1 9.3 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-CW PF07496.15 GAX25825.1 - 2.6e-29 101.0 24.2 1.3e-14 54.0 8.4 3.2 3 0 0 3 3 3 2 CW-type Zinc Finger PHD PF00628.29 GAX25825.1 - 0.07 13.0 4.8 3.9 7.4 0.6 2.9 2 0 0 2 2 2 0 PHD-finger AT_hook PF02178.19 GAX25825.1 - 9.4 6.5 39.5 5.3 7.3 8.0 4.1 3 0 0 3 3 3 0 AT hook motif Pkinase PF00069.25 GAX25826.1 - 2.3e-13 50.1 0.0 5.1e-13 49.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX25826.1 - 6.3e-12 45.3 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRV PF01816.17 GAX25826.1 - 0.0073 16.6 0.4 0.18 12.3 0.0 3.1 3 0 0 3 3 3 1 Leucine rich repeat variant DUF777 PF05606.11 GAX25826.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) TFIIA PF03153.13 GAX25826.1 - 3.6 7.5 9.6 4.5 7.2 9.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAP PF02037.27 GAX25827.1 - 2.1e-10 40.1 2.3 4.2e-10 39.1 1.8 1.8 2 0 0 2 2 2 1 SAP domain DLH PF01738.18 GAX25827.1 - 2.2e-09 37.2 0.0 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Telomere_Sde2_2 PF13297.6 GAX25827.1 - 0.0026 17.3 0.1 0.0058 16.2 0.1 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal RsdA_SigD_bd PF16751.5 GAX25827.1 - 0.05 13.9 0.3 3.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Anti-sigma-D factor RsdA to sigma factor binding region Abhydrolase_6 PF12697.7 GAX25827.1 - 0.086 13.4 0.2 0.17 12.5 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family LMBR1 PF04791.16 GAX25828.1 - 1.7 7.5 2.6 2 7.2 2.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein FrhB_FdhB_C PF04432.13 GAX25829.1 - 1.8e-29 102.6 0.0 3e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 GAX25829.1 - 3.6e-15 55.9 0.0 7.7e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Pkinase PF00069.25 GAX25830.1 - 1e-72 244.7 0.0 1.4e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX25830.1 - 4.9e-41 140.7 0.0 7.9e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 GAX25830.1 - 4.8e-37 126.0 2.5 2.3e-17 62.9 0.4 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 GAX25830.1 - 2.6e-10 40.1 0.0 1.2e-07 31.4 0.0 2.5 2 1 1 3 3 3 2 Kinase-like APH PF01636.23 GAX25830.1 - 0.0099 15.8 0.2 0.023 14.6 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family MCM PF00493.23 GAX25831.1 - 2.4e-96 321.1 0.0 3.7e-96 320.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAX25831.1 - 3.2e-29 101.3 0.0 5.7e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAX25831.1 - 1.9e-22 79.5 1.1 4.9e-22 78.2 1.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAX25831.1 - 8.7e-08 31.8 0.3 6.8e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAX25831.1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) VWA_2 PF13519.6 GAX25832.1 - 2.2e-16 60.4 0.1 1.3e-15 57.9 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 GAX25832.1 - 5.4e-07 29.1 27.2 0.00043 20.0 6.1 4.1 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.14 GAX25832.1 - 0.086 12.6 0.1 0.43 10.4 0.0 2.0 2 1 0 2 2 2 0 Ssl1-like ocr PF08684.10 GAX25833.1 - 0.078 13.4 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA mimic ocr Virul_fac_BrkB PF03631.15 GAX25833.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Virulence factor BrkB FtsJ PF01728.19 GAX25834.1 - 1.9e-27 96.5 0.0 2.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cauli_VI PF01693.16 GAX25834.1 - 0.013 15.7 0.4 0.034 14.4 0.4 1.7 1 0 0 1 1 1 0 Caulimovirus viroplasmin LRR_4 PF12799.7 GAX25835.1 - 0.25 11.8 1.7 9.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Bestrophin PF01062.21 GAX25836.1 - 3.5e-29 102.1 2.8 5.2e-29 101.6 2.8 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ERF PF04404.12 GAX25837.1 - 0.089 12.6 0.3 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 ERF superfamily Chloroa_b-bind PF00504.21 GAX25838.1 - 2.4e-33 116.0 0.5 8.3e-33 114.2 0.0 1.8 2 0 0 2 2 2 1 Chlorophyll A-B binding protein DUF4148 PF13663.6 GAX25838.1 - 0.29 11.4 2.9 0.6 10.3 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) PsbM PF05151.12 GAX25839.1 - 0.00034 20.4 0.5 0.00034 20.4 0.5 2.8 2 1 0 2 2 2 1 Photosystem II reaction centre M protein (PsbM) YfhO PF09586.10 GAX25839.1 - 0.023 13.0 1.5 0.026 12.8 1.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO COA2 PF17051.5 GAX25839.1 - 0.091 12.8 1.1 0.16 12.1 0.2 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase assembly factor 2 Sugar_tr PF00083.24 GAX25840.1 - 2e-92 310.4 25.4 2.4e-92 310.2 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX25840.1 - 5.7e-32 111.0 35.5 2.5e-31 108.9 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAX25840.1 - 2.7e-05 22.8 3.9 2.7e-05 22.8 3.9 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CNOT1_TTP_bind PF16417.5 GAX25840.1 - 0.065 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF4191 PF13829.6 GAX25840.1 - 0.21 10.9 0.1 0.21 10.9 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) UQ_con PF00179.26 GAX25841.1 - 6.3e-28 97.2 0.0 7.2e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX25841.1 - 0.0084 15.8 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RVT_2 PF07727.14 GAX25842.1 - 2.3e-22 79.8 0.0 4.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX25842.1 - 0.00025 21.2 0.1 0.0027 17.9 0.1 2.6 3 0 0 3 3 3 1 Integrase core domain AMP-binding PF00501.28 GAX25843.1 - 9.8e-84 281.4 0.0 1.3e-83 281.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 GAX25843.1 - 0.062 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) ADH_zinc_N PF00107.26 GAX25845.1 - 0.065 13.2 0.5 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Dioxygenase_C PF00775.21 GAX25847.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase Dicty_spore_N PF04562.12 GAX25847.1 - 1.2 9.9 5.9 22 5.8 5.6 2.2 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus UCR_UQCRX_QCR9 PF05365.12 GAX25848.1 - 0.00031 20.6 2.1 0.00049 20.0 2.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mito_carr PF00153.27 GAX25849.1 - 1e-18 67.0 0.0 3.6e-08 33.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein HECT_2 PF09814.9 GAX25852.1 - 4.1e-18 65.4 3.1 4.1e-18 65.4 3.1 1.8 2 0 0 2 2 2 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-MYND PF01753.18 GAX25852.1 - 1.4e-07 31.5 23.3 1.4e-07 31.5 23.3 3.1 3 0 0 3 3 3 1 MYND finger DUF5327 PF17261.2 GAX25852.1 - 5.8 7.7 7.4 14 6.5 7.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Glutaredoxin PF00462.24 GAX25853.1 - 2.6e-15 56.4 0.0 9.5e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Mpv17_PMP22 PF04117.12 GAX25854.1 - 1.1e-14 54.3 3.6 2.3e-14 53.3 3.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family IMS PF00817.20 GAX25856.1 - 4.3e-22 78.7 0.0 7.5e-21 74.7 0.0 2.5 1 1 0 1 1 1 1 impB/mucB/samB family DER1 PF04511.15 GAX25858.1 - 1.1e-38 133.1 9.3 1.2e-38 132.9 9.3 1.0 1 0 0 1 1 1 1 Der1-like family BHD_1 PF10403.9 GAX25859.1 - 2.1e-13 49.9 0.0 4.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 GAX25859.1 - 3.6e-13 49.7 0.0 6.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 GAX25859.1 - 3.8e-12 47.0 1.9 2.5e-11 44.3 1.9 2.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 GAX25859.1 - 0.00014 21.5 1.8 0.00059 19.5 1.8 2.0 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain APOC4 PF15119.6 GAX25859.1 - 0.017 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein C4 Transglut_core PF01841.19 GAX25859.1 - 0.038 14.4 0.0 0.38 11.2 0.0 2.6 3 0 0 3 3 3 0 Transglutaminase-like superfamily Myb_DNA-binding PF00249.31 GAX25860.1 - 0.00054 20.1 0.4 0.098 12.9 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.24 GAX25860.1 - 0.019 15.7 0.0 0.019 15.7 0.0 2.5 2 0 0 2 2 2 0 ELM2 domain Myb_DNA-bind_6 PF13921.6 GAX25860.1 - 0.15 12.3 1.6 1.3 9.3 0.1 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pex16 PF08610.10 GAX25862.1 - 4.9e-17 62.1 1.7 1.2e-16 60.8 1.7 1.6 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Orn_Arg_deC_N PF02784.16 GAX25863.1 - 1.9e-25 89.7 0.0 2.8e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAX25863.1 - 5e-14 52.3 0.0 6.3e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CTP_transf_1 PF01148.20 GAX25864.1 - 1.1e-47 163.1 14.9 1.1e-47 163.1 14.9 1.5 2 0 0 2 2 2 1 Cytidylyltransferase family MFS_1 PF07690.16 GAX25865.1 - 3e-26 92.2 29.9 7.6e-18 64.5 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4181 PF13789.6 GAX25865.1 - 0.41 10.9 2.0 2 8.7 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Polyketide_cyc PF03364.20 GAX25868.1 - 7.2e-15 55.3 0.0 1.2e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAX25868.1 - 2.8e-05 24.4 0.0 4.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3689 PF12463.8 GAX25869.1 - 2.7e-69 233.9 1.2 7.1e-53 179.9 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3689) ABC1 PF03109.16 GAX25872.1 - 4.6e-20 72.0 0.0 1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.17 GAX25872.1 - 5e-09 35.8 0.0 0.00017 20.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAX25872.1 - 0.00016 21.2 0.0 0.049 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 GAX25872.1 - 0.00027 20.6 0.0 0.00059 19.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Fructosamin_kin PF03881.14 GAX25872.1 - 0.0055 15.9 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase APH PF01636.23 GAX25872.1 - 0.04 13.8 0.5 0.096 12.6 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyoxalase PF00903.25 GAX25873.1 - 9.2e-08 32.3 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-CCHC_5 PF14787.6 GAX25873.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger TAL_FSA PF00923.19 GAX25874.1 - 2e-75 253.8 0.0 2.3e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF3493 PF11998.8 GAX25875.1 - 2.2e-23 82.2 0.1 4.7e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 HLH PF00010.26 GAX25877.1 - 7.3e-09 35.5 1.6 1e-08 35.0 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 GAX25877.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 GAX25877.1 - 0.1 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain CDC45 PF02724.14 GAX25877.1 - 0.52 8.5 4.9 0.76 8.0 4.0 1.7 2 0 0 2 2 2 0 CDC45-like protein ERO1 PF04137.15 GAX25878.1 - 6.3e-47 160.5 0.4 8.2e-46 156.8 0.4 2.0 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Hexapep PF00132.24 GAX25879.1 - 7.8e-14 50.8 12.6 3.2e-05 23.5 0.4 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAX25879.1 - 3.7e-05 23.4 7.7 0.013 15.2 0.5 3.7 2 1 2 4 4 4 4 Hexapeptide repeat of succinyl-transferase Imm70 PF15601.6 GAX25879.1 - 0.073 12.6 0.0 0.23 11.0 0.0 1.8 1 1 1 2 2 2 0 Immunity protein 70 CKS PF01111.19 GAX25880.1 - 2.3e-35 120.7 0.6 2.9e-35 120.3 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit His_Phos_1 PF00300.22 GAX25881.1 - 0.0097 15.6 0.1 0.31 10.7 0.0 2.6 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) DUF1515 PF07439.11 GAX25882.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) RcpB PF16971.5 GAX25883.1 - 0.018 14.9 0.2 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Rough colony protein B, tight adherence - tad - subunit Methyltransf_16 PF10294.9 GAX25885.1 - 1.3e-23 83.6 0.0 3.5e-23 82.2 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX25885.1 - 4.5e-06 26.3 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX25885.1 - 9.9e-05 21.9 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 GAX25885.1 - 0.00031 20.5 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GAX25885.1 - 0.0017 19.0 0.1 0.0084 16.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX25885.1 - 0.014 16.1 0.1 0.066 14.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain BLM_N PF16202.5 GAX25885.1 - 0.057 12.5 0.4 0.082 12.0 0.4 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Ribosomal_S7e PF01251.18 GAX25886.1 - 1.1e-69 233.9 0.2 1.2e-69 233.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DNA_pol_E_B PF04042.16 GAX25887.1 - 2.5e-38 131.6 1.1 2.5e-38 131.6 1.1 1.8 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 GAX25887.1 - 1.4e-05 25.3 0.2 0.00072 19.6 0.2 2.1 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.6 GAX25887.1 - 0.1 11.9 0.0 7.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily DUF2680 PF10925.8 GAX25887.1 - 0.14 12.2 0.2 0.34 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) TruB_N PF01509.18 GAX25888.1 - 6e-47 159.7 0.0 9e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAX25888.1 - 2.6e-05 24.3 0.0 4.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Ank_2 PF12796.7 GAX25889.1 - 1.4e-52 176.2 9.1 3.8e-16 59.5 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX25889.1 - 7.8e-42 136.5 5.3 6.6e-05 23.0 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 GAX25889.1 - 1.1e-41 140.6 8.2 8.1e-10 39.0 0.1 6.6 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 GAX25889.1 - 3e-33 112.8 11.1 5e-05 23.6 0.1 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 GAX25889.1 - 3.3e-32 110.1 4.2 4.9e-08 33.1 0.0 7.5 1 1 7 8 8 8 7 Ankyrin repeats (many copies) PhyH PF05721.13 GAX25890.1 - 5.3e-11 43.2 1.0 1.3e-10 41.9 0.1 2.1 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) SMC_N PF02463.19 GAX25891.1 - 7e-65 218.5 18.5 1.5e-63 214.2 18.5 3.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAX25891.1 - 1.3e-21 77.0 0.7 5.7e-21 75.0 0.7 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAX25891.1 - 2.1e-10 40.9 6.5 4.7e-05 23.3 0.7 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAX25891.1 - 1.3e-05 25.8 37.9 1.3e-05 25.8 37.9 6.9 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAX25891.1 - 7.3e-05 22.4 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 GAX25891.1 - 0.0005 19.9 42.2 0.0061 16.3 19.5 4.7 3 1 0 3 3 3 1 AAA ATPase domain GAS PF13851.6 GAX25891.1 - 0.0046 16.3 12.5 0.0046 16.3 12.5 7.7 4 2 3 7 7 7 3 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 GAX25891.1 - 0.0099 16.4 0.0 0.0099 16.4 0.0 6.1 4 2 0 4 4 4 2 ABC transporter LacI PF00356.21 GAX25891.1 - 0.053 13.3 1.1 3.6 7.5 0.0 3.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family NAD_binding_10 PF13460.6 GAX25893.1 - 2.7e-22 79.6 0.6 4.8e-22 78.7 0.6 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX25893.1 - 6.7e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAX25893.1 - 0.00014 21.5 0.0 0.0004 19.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAX25893.1 - 0.00047 20.4 1.1 0.0054 17.0 0.1 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAX25893.1 - 0.00075 19.0 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase HIM1 PF08732.10 GAX25893.1 - 0.0031 17.1 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 HIM1 F420_oxidored PF03807.17 GAX25893.1 - 0.0032 18.0 0.1 0.0097 16.5 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF364 PF04016.12 GAX25893.1 - 0.0034 17.0 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative heavy-metal chelation KR PF08659.10 GAX25893.1 - 0.0035 17.3 0.1 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 GAX25893.1 - 0.0038 16.9 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 GAX25893.1 - 0.0058 16.0 0.6 0.011 15.1 0.2 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 GAX25893.1 - 0.011 16.1 0.1 0.023 15.2 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding RmlD_sub_bind PF04321.17 GAX25893.1 - 0.024 13.7 0.2 0.23 10.5 0.2 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain AlaDh_PNT_C PF01262.21 GAX25893.1 - 0.042 13.2 0.8 0.094 12.0 0.2 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAX25893.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAX25893.1 - 0.22 10.5 1.5 0.42 9.6 0.0 2.1 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Vac14_Fig4_bd PF11916.8 GAX25894.1 - 1.8e-69 233.0 5.0 1.8e-69 233.0 5.0 2.5 4 0 0 4 4 4 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 GAX25894.1 - 2.9e-42 143.2 0.0 8.3e-36 122.5 0.0 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAX25894.1 - 1.9e-14 52.5 5.4 1.5e-05 24.8 0.0 5.9 7 0 0 7 7 6 3 HEAT repeat Cnd1 PF12717.7 GAX25894.1 - 5.2e-11 42.9 0.7 0.00085 19.4 0.0 4.9 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX25894.1 - 2.9e-10 40.4 6.9 3.8e-05 24.1 0.0 4.9 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 GAX25894.1 - 8.4e-09 35.7 0.9 0.15 12.5 0.0 5.3 2 2 3 5 5 5 3 HEAT repeats Tti2 PF10521.9 GAX25894.1 - 2.2e-06 27.4 3.3 2.3e-05 24.1 0.0 3.8 3 1 1 4 4 4 1 Tti2 family CLASP_N PF12348.8 GAX25894.1 - 2.7e-06 27.1 1.4 0.067 12.7 0.0 4.7 3 2 2 5 5 5 3 CLASP N terminal MMS19_C PF12460.8 GAX25894.1 - 0.039 13.1 0.0 0.039 13.1 0.0 3.7 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 GAX25894.1 - 0.046 13.9 1.7 5.6 7.2 0.1 3.9 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 GAX25894.1 - 0.32 11.1 4.8 0.51 10.5 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SF3A2 PF16835.5 GAX25895.1 - 5.9e-31 106.7 0.0 1.1e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 GAX25895.1 - 9.8e-07 29.0 1.1 2.1e-06 27.9 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 GAX25895.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF4245 PF14030.6 GAX25895.1 - 0.061 13.3 0.1 0.18 11.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4245) FeThRed_B PF02943.15 GAX25896.1 - 1.1e-36 125.0 4.1 1.7e-36 124.4 4.1 1.2 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain ADK PF00406.22 GAX25897.1 - 3.2e-50 170.1 0.0 4.3e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX25897.1 - 6.1e-26 91.5 0.2 2.7e-25 89.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX25897.1 - 2.5e-07 31.3 0.1 7.8e-06 26.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX25897.1 - 1.9e-05 24.9 0.3 0.016 15.3 0.3 2.7 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 GAX25897.1 - 0.00095 19.5 0.8 0.14 12.4 0.1 2.4 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 GAX25897.1 - 0.003 17.3 0.1 0.73 9.5 0.0 2.5 1 1 0 2 2 2 2 Thymidylate kinase Cytidylate_kin PF02224.18 GAX25897.1 - 0.0038 17.0 0.2 0.0092 15.7 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase Zeta_toxin PF06414.12 GAX25897.1 - 0.0065 15.8 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin ADK_lid PF05191.14 GAX25897.1 - 0.022 14.7 0.0 0.055 13.5 0.0 1.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid dNK PF01712.19 GAX25897.1 - 0.059 13.2 0.7 12 5.7 0.1 2.5 2 1 1 3 3 3 0 Deoxynucleoside kinase dCMP_cyt_deam_1 PF00383.23 GAX25898.1 - 1.4e-12 47.3 0.2 2.3e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX25898.1 - 5e-05 23.1 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase FixQ PF05545.11 GAX25898.1 - 0.043 13.8 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ HMG_box PF00505.19 GAX25899.1 - 1e-11 45.1 7.2 3.6e-07 30.5 4.6 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX25899.1 - 1.7e-05 25.3 10.1 0.00099 19.7 1.8 2.7 3 0 0 3 3 3 2 HMG-box domain YABBY PF04690.13 GAX25899.1 - 0.084 13.4 0.2 0.084 13.4 0.2 2.1 2 0 0 2 2 2 0 YABBY protein PPL5 PF18168.1 GAX25899.1 - 0.25 10.6 1.7 0.43 9.8 1.7 1.3 1 0 0 1 1 1 0 Prim-pol family 5 CHORD PF04968.12 GAX25900.1 - 1.1e-18 67.7 7.1 1.9e-18 66.9 7.1 1.3 1 0 0 1 1 1 1 CHORD Pex2_Pex12 PF04757.14 GAX25902.1 - 2.3e-12 47.0 0.8 3.3e-12 46.5 0.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-TFIIB PF13453.6 GAX25902.1 - 0.09 12.1 0.1 0.23 10.8 0.1 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Pkinase_Tyr PF07714.17 GAX25903.1 - 2.1e-57 194.4 0.0 3.2e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX25903.1 - 2.9e-50 171.1 0.0 5.2e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GAX25903.1 - 4.9e-05 22.8 0.0 9.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAX25903.1 - 0.00011 21.1 0.4 0.00023 20.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAX25903.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX25903.1 - 0.024 14.6 0.0 0.069 13.1 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Methyltrn_RNA_3 PF02598.17 GAX25906.1 - 1.3e-95 320.2 0.0 1.7e-95 319.8 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Presenilin PF01080.17 GAX25906.1 - 0.24 10.1 0.8 0.42 9.3 0.8 1.3 1 0 0 1 1 1 0 Presenilin Glyco_trans_1_2 PF13524.6 GAX25907.1 - 4.2e-14 52.7 0.0 7.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_C1 PF00112.23 GAX25908.1 - 4.6e-52 177.3 0.0 6.5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX25908.1 - 2.5e-09 37.4 0.9 3.6e-09 36.9 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAX25908.1 - 0.013 14.3 0.3 2 7.1 0.1 2.2 2 0 0 2 2 2 0 Peptidase C1-like family DUF5637 PF18687.1 GAX25908.1 - 3.4 7.7 7.9 35 4.5 3.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5637) CbiX PF01903.17 GAX25909.1 - 3.9e-21 75.4 0.2 5.7e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 GAX25909.1 - 0.025 13.9 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Cnd1 PF12717.7 GAX25910.1 - 9.8e-21 74.5 15.1 5e-12 46.1 0.0 6.7 7 1 0 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX25910.1 - 4.8e-11 41.9 3.6 0.048 13.9 0.0 7.5 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 GAX25910.1 - 0.0082 16.5 5.9 0.34 11.3 0.2 4.9 3 2 2 5 5 5 2 HEAT repeats Cnd3 PF12719.7 GAX25910.1 - 0.016 14.5 3.5 0.053 12.7 0.1 3.4 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 GAX25910.1 - 0.019 15.5 9.7 6.2 7.4 0.2 6.2 6 0 0 6 6 6 0 HEAT-like repeat Arm PF00514.23 GAX25910.1 - 0.2 11.8 1.0 4.8 7.4 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 GAX25910.1 - 0.22 11.9 0.1 0.22 11.9 0.1 4.0 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 GAX25910.1 - 0.34 10.6 4.0 1.2 8.8 0.0 3.6 3 1 2 5 5 5 0 Domain of unknown function (DUF4042) Glutaminase PF04960.15 GAX25911.1 - 7.8e-95 317.3 0.0 1.4e-94 316.5 0.0 1.4 1 0 0 1 1 1 1 Glutaminase TerB PF05099.13 GAX25911.1 - 0.00014 21.8 0.2 0.00036 20.5 0.2 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 GAX25911.1 - 0.0011 19.3 0.0 0.004 17.5 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain Poxvirus_B22R_N PF13169.6 GAX25911.1 - 0.073 13.6 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal QRPTase_C PF01729.19 GAX25911.1 - 0.12 12.1 0.1 9.4 6.0 0.4 2.3 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Glyco_hydro_125 PF06824.11 GAX25912.1 - 8.3e-90 301.6 0.0 1.3e-89 301.0 0.0 1.2 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Glyco_hydro_125 PF06824.11 GAX25913.1 - 1.3e-115 386.6 0.0 2.4e-115 385.8 0.0 1.4 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) HMG_box PF00505.19 GAX25914.1 - 1.1e-12 48.2 0.4 1.9e-06 28.2 0.2 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX25914.1 - 7.9e-06 26.4 0.4 0.057 14.0 0.1 2.5 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.13 GAX25914.1 - 0.053 14.1 0.1 0.053 14.1 0.1 2.2 2 1 0 2 2 2 0 YABBY protein adh_short PF00106.25 GAX25915.1 - 2.9e-31 108.5 0.1 2.5e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX25915.1 - 2.7e-17 63.1 0.2 5.2e-16 58.9 0.1 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX25915.1 - 3.9e-10 39.9 0.1 6.4e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX25915.1 - 0.0003 20.0 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAX25915.1 - 0.035 13.6 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAX25916.1 - 1.4e-33 116.1 0.0 1.4e-25 89.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX25916.1 - 2.1e-17 63.5 0.0 3.4e-15 56.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX25916.1 - 1.4e-11 44.7 0.1 2.4e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX25916.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SRP68 PF16969.5 GAX25916.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 adh_short PF00106.25 GAX25917.1 - 3.1e-30 105.1 0.2 3.2e-24 85.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX25917.1 - 2e-18 66.8 0.0 1.1e-15 57.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX25917.1 - 6.5e-09 35.9 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 KR domain SRP68 PF16969.5 GAX25917.1 - 0.034 13.1 0.1 0.04 12.9 0.1 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Polysacc_synt_2 PF02719.15 GAX25917.1 - 0.058 12.5 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAX25917.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family UNC119_bdg PF15435.6 GAX25917.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue adh_short PF00106.25 GAX25918.1 - 2.2e-28 99.0 0.0 2.5e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX25918.1 - 8.6e-16 58.2 0.3 3.8e-14 52.8 0.1 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX25918.1 - 4.9e-10 39.6 0.1 7.2e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX25918.1 - 0.017 14.3 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein BAAT_C PF08840.11 GAX25918.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AAR2 PF05282.11 GAX25919.1 - 1.7e-24 86.9 1.7 2e-23 83.4 1.7 2.2 1 1 0 1 1 1 1 AAR2 protein bZIP_C PF12498.8 GAX25919.1 - 0.065 14.2 0.0 0.18 12.8 0.0 1.7 1 0 0 1 1 1 0 Basic leucine-zipper C terminal Ribonuc_red_2_N PF08471.10 GAX25919.1 - 0.14 12.4 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase RNA_pol_3_Rpc31 PF11705.8 GAX25919.1 - 5.9 7.1 8.9 12 6.1 8.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Fcf1 PF04900.12 GAX25920.1 - 1.8e-34 118.1 1.8 3.4e-34 117.2 1.8 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 GAX25920.1 - 1.6e-12 47.7 0.0 7.6e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 PIN like domain DUF1175 PF06672.11 GAX25920.1 - 0.036 13.7 0.1 0.052 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) Tombus_P33 PF08500.10 GAX25923.1 - 0.079 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Tombusvirus p33 TackOD1 PF18551.1 GAX25923.1 - 0.17 11.6 2.3 0.17 11.5 0.8 1.8 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_10 PF10058.9 GAX25923.1 - 0.23 11.2 1.3 3.8 7.3 0.2 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Rab5ip PF07019.12 GAX25924.1 - 2.4e-17 63.3 7.9 3.1e-17 62.9 7.9 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) GAGA PF09237.11 GAX25925.1 - 0.00014 21.6 0.1 0.00073 19.3 0.0 2.1 2 0 0 2 2 2 1 GAGA factor zf-RING_5 PF14634.6 GAX25925.1 - 0.02 14.9 2.6 0.24 11.4 0.0 3.0 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX25925.1 - 0.041 13.7 2.3 43 4.1 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 GAX25925.1 - 0.15 11.5 1.5 1.3 8.5 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 GAX25925.1 - 0.23 11.5 2.4 5.7 7.0 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.6 GAX25925.1 - 0.54 10.6 4.2 1.5 9.2 0.0 3.1 3 0 0 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.6 GAX25925.1 - 1.2 9.0 5.0 29 4.6 0.4 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C4_Topoisom PF01396.19 GAX25925.1 - 3.4 7.5 5.7 17 5.3 0.2 3.2 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.12 GAX25925.1 - 7 6.7 5.9 8.1 6.5 0.5 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger AAA_11 PF13086.6 GAX25926.1 - 1.2e-12 48.2 0.0 1.3e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX25926.1 - 5.5e-09 36.0 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX25926.1 - 6.6e-08 33.0 0.0 7.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 GAX25926.1 - 0.00021 20.9 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 GAX25926.1 - 0.0004 19.7 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 GAX25926.1 - 0.00095 19.6 0.1 0.0032 17.9 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GAX25926.1 - 0.007 16.4 0.0 0.0093 16.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 GAX25926.1 - 0.0087 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX25926.1 - 0.018 15.4 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 GAX25926.1 - 0.048 13.1 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 GAX25926.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 GAX25926.1 - 0.085 13.4 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAX25926.1 - 0.094 12.5 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Helicase_RecD PF05127.14 GAX25926.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Helicase ATPase PF06745.13 GAX25926.1 - 0.17 11.2 0.3 0.43 9.9 0.3 1.7 1 1 0 1 1 1 0 KaiC zf-RING_2 PF13639.6 GAX25927.1 - 1e-08 35.3 5.8 2.7e-08 34.0 5.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 GAX25927.1 - 9.4e-06 25.6 4.5 1.9e-05 24.6 4.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 GAX25927.1 - 2.1e-05 24.6 4.6 2.1e-05 24.6 4.6 1.8 2 0 0 2 2 2 1 RING-variant domain zf-rbx1 PF12678.7 GAX25927.1 - 0.00053 20.2 5.3 0.00053 20.2 5.3 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAX25927.1 - 0.015 15.1 4.9 0.015 15.1 4.9 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX25927.1 - 0.02 14.6 4.2 0.16 11.8 4.2 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 GAX25927.1 - 0.083 13.1 5.4 1.1 9.5 5.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 GAX25927.1 - 2.3 8.1 13.3 0.13 12.1 6.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GAX25928.1 - 4.9e-10 39.6 16.9 9.1e-10 38.7 16.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX25928.1 - 2e-07 31.2 11.5 4e-07 30.2 11.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX25928.1 - 7.4e-07 28.9 14.8 1.6e-06 27.9 14.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX25928.1 - 1e-06 28.4 8.0 2.3e-06 27.3 8.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 GAX25928.1 - 3.7e-05 23.6 12.5 6.4e-05 22.8 12.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAX25928.1 - 0.0012 18.7 11.9 0.0027 17.5 11.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX25928.1 - 0.0066 16.5 13.1 0.02 15.0 13.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX25928.1 - 0.0097 15.9 9.8 0.0097 15.9 9.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 GAX25928.1 - 0.069 12.8 14.7 0.12 12.0 14.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type EMC3_TMCO1 PF01956.16 GAX25928.1 - 0.17 11.6 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like zf-C3HC4_3 PF13920.6 GAX25928.1 - 0.19 11.6 18.6 0.34 10.8 18.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.28 GAX25929.1 - 2.6e-20 72.3 0.0 8.1e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain IRK_C PF17655.1 GAX25930.1 - 6.6e-21 74.7 0.0 3.4e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 GAX25930.1 - 1.1e-09 38.2 10.9 3.2e-08 33.5 10.9 2.2 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 GAX25930.1 - 0.0016 18.3 9.0 0.0039 17.1 9.0 1.7 1 0 0 1 1 1 1 Ion channel Fer2 PF00111.27 GAX25931.1 - 4.6e-07 29.7 0.8 6.6e-07 29.2 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 GAX25931.1 - 4.7e-05 23.3 0.2 5.8e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 GAX25931.1 - 0.00091 19.2 1.8 0.0033 17.4 1.8 1.8 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zip PF02535.22 GAX25932.1 - 1e-12 48.0 21.5 9.6e-10 38.2 12.8 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter Pox_EPC_I2-L1 PF12575.8 GAX25932.1 - 0.11 12.7 0.1 4.5 7.6 0.1 2.7 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 Fis1_TPR_C PF14853.6 GAX25933.1 - 1.1e-07 31.8 0.3 2.5e-07 30.6 0.3 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 GAX25933.1 - 4.2e-05 24.0 2.5 7.4e-05 23.2 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 GAX25933.1 - 0.00012 21.7 0.7 0.00022 20.8 0.0 1.8 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 GAX25933.1 - 0.0014 18.6 2.8 0.0027 17.7 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX25933.1 - 0.0033 18.1 1.1 0.0033 18.1 1.1 2.6 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX25933.1 - 0.0035 17.9 0.2 0.0035 17.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX25933.1 - 0.0036 17.8 0.8 0.0036 17.8 0.8 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF883 PF05957.13 GAX25933.1 - 0.0069 17.0 1.6 0.017 15.7 1.6 1.7 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) ANAPC3 PF12895.7 GAX25933.1 - 0.035 14.3 0.7 0.035 14.3 0.7 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAX25933.1 - 0.042 14.1 3.9 0.2 12.0 3.8 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25933.1 - 0.33 11.6 14.7 0.5 11.1 9.6 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAX25933.1 - 0.36 10.9 12.5 2.3 8.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Aa_trans PF01490.18 GAX25934.1 - 3.2e-10 39.3 3.9 4.2e-10 38.9 3.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein KIX PF02172.16 GAX25935.1 - 0.0036 17.5 0.1 0.0064 16.7 0.1 1.4 1 0 0 1 1 1 1 KIX domain Mak10 PF04112.13 GAX25936.1 - 1.1e-16 60.8 0.1 2.8e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_L1 PF00687.21 GAX25937.1 - 5.3e-40 137.3 0.6 5.3e-40 137.3 0.6 2.4 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Asp-B-Hydro_N PF05279.11 GAX25937.1 - 7 6.6 35.7 17 5.4 35.7 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region APG6 PF04111.12 GAX25938.1 - 9.2e-35 120.2 0.2 7.6e-27 94.4 0.1 2.7 3 0 0 3 3 3 2 Apg6 BARA domain PP_kinase PF02503.17 GAX25938.1 - 0.11 12.1 0.6 0.19 11.3 0.6 1.3 1 0 0 1 1 1 0 Polyphosphate kinase middle domain Cwf_Cwc_15 PF04889.12 GAX25938.1 - 0.2 11.4 2.1 0.35 10.6 2.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPR_2 PF13041.6 GAX25939.1 - 2e-20 72.7 0.0 7e-08 32.5 0.0 7.0 7 1 1 8 8 8 3 PPR repeat family PPR_3 PF13812.6 GAX25939.1 - 1.2e-10 41.3 0.0 0.0061 16.6 0.0 5.6 6 2 1 7 7 7 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX25939.1 - 5.4e-09 35.6 0.0 0.38 10.5 0.0 7.1 7 1 0 7 7 7 2 PPR repeat PPR_long PF17177.4 GAX25939.1 - 3.5e-08 33.1 1.6 0.0029 17.0 0.0 4.5 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX25939.1 - 0.014 15.6 10.8 0.21 11.9 0.0 6.6 7 2 0 7 7 7 0 PPR repeat Dak2 PF02734.17 GAX25939.1 - 0.19 11.6 2.8 15 5.5 0.7 3.2 3 0 0 3 3 3 0 DAK2 domain GCS PF03074.16 GAX25941.1 - 3.1e-159 530.2 0.0 4.5e-159 529.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase Nuc_sug_transp PF04142.15 GAX25942.1 - 9.9e-113 376.4 19.5 1.2e-112 376.2 19.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAX25942.1 - 5.6e-08 32.3 17.9 1.4e-07 31.0 17.9 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX25942.1 - 6.1e-07 29.7 33.6 1e-05 25.7 10.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX25942.1 - 8.4e-06 25.2 6.5 8.4e-06 25.2 6.5 2.4 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 GAX25942.1 - 0.0013 17.8 3.9 0.0013 17.8 3.9 2.1 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Multi_Drug_Res PF00893.19 GAX25942.1 - 0.017 15.7 1.7 0.017 15.7 1.7 3.2 2 2 1 3 3 3 0 Small Multidrug Resistance protein Halogen_Hydrol PF10112.9 GAX25942.1 - 0.068 13.2 0.8 1.9 8.5 0.4 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Phage_holin_5_1 PF06946.11 GAX25942.1 - 4.5 7.7 9.0 35 4.9 0.1 3.9 2 1 1 3 3 3 0 Bacteriophage A118-like holin, Hol118 TMEM234 PF10639.9 GAX25942.1 - 8.2 6.5 13.1 0.27 11.3 2.9 2.6 2 1 0 2 2 2 0 Putative transmembrane family 234 PseudoU_synth_1 PF01416.20 GAX25943.1 - 5.2e-29 100.9 0.0 5.7e-27 94.3 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF5565 PF17720.1 GAX25943.1 - 0.046 12.6 0.3 0.4 9.5 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5565) FBPase PF00316.20 GAX25944.1 - 3.4e-62 209.3 0.1 1.1e-61 207.6 0.1 1.7 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain PDZ_6 PF17820.1 GAX25945.1 - 6.8e-05 22.6 0.0 0.00028 20.7 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX25945.1 - 0.011 16.1 0.0 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 PDZ domain L_lactis_RepB_C PF06430.12 GAX25945.1 - 0.013 15.5 0.9 0.037 14.0 0.9 1.7 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus DUF261 PF03196.13 GAX25945.1 - 0.022 14.9 0.2 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF261 Rhodanese PF00581.20 GAX25946.1 - 1.3e-17 64.2 0.0 9e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain HSF_DNA-bind PF00447.17 GAX25947.1 - 3.8e-21 75.5 0.1 5.8e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Helicase_C_2 PF13307.6 GAX25948.1 - 7.3e-51 172.7 0.0 6e-50 169.8 0.0 2.3 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAX25948.1 - 2.8e-46 157.3 0.0 5.1e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 GAX25948.1 - 8.4e-07 29.1 0.1 0.0005 20.1 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX25948.1 - 0.0014 18.4 0.1 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAX25948.1 - 0.021 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain HBB PF06777.11 GAX25948.1 - 0.087 12.5 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF3947 PF13135.6 GAX25948.1 - 2.9 8.2 5.7 17 5.7 3.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) TPR_12 PF13424.6 GAX25949.1 - 4.2e-28 97.4 0.0 2.2e-09 37.5 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX25949.1 - 2.9e-24 83.2 0.0 0.001 19.0 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX25949.1 - 4e-22 77.0 0.0 0.00039 20.1 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX25949.1 - 4.7e-18 64.4 0.0 0.013 15.4 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX25949.1 - 4.6e-17 60.7 0.0 0.012 15.8 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX25949.1 - 1.8e-14 52.6 0.1 0.012 15.6 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX25949.1 - 9.8e-10 38.4 0.0 0.57 11.1 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX25949.1 - 1.7e-08 35.0 0.0 0.022 15.4 0.0 5.2 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX25949.1 - 2.6e-08 33.6 0.0 1.8e-06 27.6 0.0 2.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_6 PF13174.6 GAX25949.1 - 6.7e-08 32.7 0.0 8.7 7.2 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX25949.1 - 2.7e-07 30.2 0.0 0.11 12.2 0.1 4.8 5 1 0 5 5 5 2 TPR repeat TPR_19 PF14559.6 GAX25949.1 - 2.3e-05 24.8 0.0 0.15 12.6 0.0 5.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAX25949.1 - 0.00012 22.3 0.0 2.2 9.2 0.0 4.7 6 0 0 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX25949.1 - 0.00032 20.8 0.0 0.17 12.1 0.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAX25949.1 - 0.002 18.4 0.0 4.6 7.8 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAX25949.1 - 0.003 17.7 0.0 5.3 7.3 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAX25949.1 - 0.032 13.4 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX25949.1 - 0.057 12.9 0.1 3 7.4 0.0 3.1 3 0 0 3 3 3 0 SHNi-TPR Paf67 PF10255.9 GAX25949.1 - 0.16 10.9 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 ATP-synt_10 PF05176.14 GAX25951.1 - 1.5e-27 96.4 0.0 2.2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein Lipocalin_2 PF08212.12 GAX25952.1 - 0.00012 22.0 0.0 0.0034 17.3 0.1 2.3 2 1 0 2 2 2 2 Lipocalin-like domain AAA_2 PF07724.14 GAX25953.1 - 2.9e-54 183.8 0.1 4e-53 180.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAX25953.1 - 1.5e-33 114.8 3.9 5.1e-33 113.1 0.1 3.2 1 1 2 3 3 3 1 AAA lid domain ClpB_D2-small PF10431.9 GAX25953.1 - 1e-26 92.8 0.1 7.6e-26 90.0 0.1 2.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GAX25953.1 - 1.6e-24 86.8 0.3 2.8e-12 47.2 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX25953.1 - 5.5e-16 58.8 0.0 3.9e-10 39.9 0.0 3.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX25953.1 - 4.7e-12 46.6 1.2 0.00018 21.9 0.0 4.8 4 1 0 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 GAX25953.1 - 2.1e-08 34.1 0.0 4.2e-05 23.3 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 GAX25953.1 - 2.6e-08 34.2 2.3 0.036 14.3 0.0 5.4 4 2 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 GAX25953.1 - 6.7e-06 25.9 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 GAX25953.1 - 9.9e-06 26.1 0.0 0.28 11.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 GAX25953.1 - 1.2e-05 24.8 0.0 0.0059 16.0 0.1 3.4 2 1 0 2 2 2 1 Bacterial TniB protein RuvB_N PF05496.12 GAX25953.1 - 2.6e-05 24.0 0.2 1.9 8.2 0.0 4.2 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 GAX25953.1 - 3.6e-05 23.8 0.0 4.6 7.1 0.0 4.2 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 GAX25953.1 - 9.8e-05 21.8 0.1 0.7 9.2 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX25953.1 - 0.0002 20.9 0.0 0.091 12.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Clp_N PF02861.20 GAX25953.1 - 0.00034 20.7 0.4 0.0082 16.2 0.0 2.8 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component AAA_14 PF13173.6 GAX25953.1 - 0.00049 20.1 0.0 1.5 8.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 GAX25953.1 - 0.00087 19.3 0.0 0.26 11.2 0.0 3.0 3 0 0 3 3 2 1 NACHT domain Roc PF08477.13 GAX25953.1 - 0.001 19.3 0.0 0.88 9.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 GAX25953.1 - 0.0013 18.8 0.0 0.24 11.4 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 GAX25953.1 - 0.0015 18.9 0.0 1.6 9.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 GAX25953.1 - 0.0021 18.1 0.0 3.6 7.6 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAX25953.1 - 0.0021 17.8 0.0 0.92 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX25953.1 - 0.0061 16.2 0.7 0.58 9.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 GAX25953.1 - 0.0063 16.8 0.1 7.5 6.8 0.0 4.0 4 0 0 4 4 3 0 AAA domain Torsin PF06309.11 GAX25953.1 - 0.012 15.7 0.0 0.095 12.8 0.0 2.3 2 0 0 2 2 2 0 Torsin RsgA_GTPase PF03193.16 GAX25953.1 - 0.014 15.3 0.0 2.5 8.0 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 GAX25953.1 - 0.017 15.6 0.0 0.67 10.5 0.0 2.9 3 0 0 3 3 2 0 ABC transporter AAA_33 PF13671.6 GAX25953.1 - 0.028 14.6 0.0 24 5.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 GAX25953.1 - 0.038 13.3 0.0 13 5.0 0.0 2.9 2 0 0 2 2 2 0 Zeta toxin TIP49 PF06068.13 GAX25953.1 - 0.048 12.9 0.0 0.5 9.5 0.0 2.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_19 PF13245.6 GAX25953.1 - 0.068 13.5 0.2 1.5 9.2 0.1 3.0 3 1 0 3 3 2 0 AAA domain AAA_3 PF07726.11 GAX25953.1 - 0.074 12.9 0.0 15 5.5 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 GAX25953.1 - 0.14 11.9 0.0 0.98 9.1 0.0 2.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein LUC7 PF03194.15 GAX25953.1 - 0.61 9.7 3.2 1.3 8.7 3.2 1.5 1 0 0 1 1 1 0 LUC7 N_terminus ABC_tran_CTD PF16326.5 GAX25953.1 - 1.6 9.0 15.5 0.071 13.4 4.3 3.6 1 1 1 3 3 3 0 ABC transporter C-terminal domain ADIP PF11559.8 GAX25953.1 - 2.3 8.3 6.6 0.8 9.8 2.7 2.2 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding VHL PF01847.16 GAX25955.1 - 0.013 15.4 0.8 0.3 11.0 0.1 3.1 2 1 0 2 2 2 0 VHL beta domain SET PF00856.28 GAX25956.1 - 1.2e-10 42.1 0.6 9.9e-10 39.1 0.1 2.4 2 1 0 2 2 2 1 SET domain Nexin_C PF08628.12 GAX25956.1 - 0.029 14.9 0.8 0.71 10.5 0.1 2.7 3 0 0 3 3 3 0 Sorting nexin C terminal TORC_M PF12885.7 GAX25956.1 - 0.038 13.9 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain DUF4239 PF14023.6 GAX25956.1 - 0.054 13.2 0.3 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF4611 PF15387.6 GAX25956.1 - 5.9 7.2 9.3 0.18 12.1 1.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) PAP_fibrillin PF04755.12 GAX25957.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 PAP_fibrillin Pkinase PF00069.25 GAX25958.1 - 4.8e-39 134.3 0.0 8.2e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX25958.1 - 1.4e-23 83.6 0.0 2.4e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX25958.1 - 0.0015 18.5 2.3 0.012 15.6 0.0 3.0 2 2 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX25958.1 - 0.0082 15.0 0.0 0.017 14.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAX25958.1 - 0.027 14.0 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ubiquitin PF00240.23 GAX25959.1 - 1e-33 114.9 0.4 2.3e-33 113.8 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin family Sod_Ni PF09055.11 GAX25959.1 - 1e-30 106.9 1.4 1.6e-30 106.2 1.4 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Rad60-SLD PF11976.8 GAX25959.1 - 5e-16 58.3 0.7 1e-15 57.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX25959.1 - 3.4e-05 24.2 0.1 0.00014 22.2 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX25959.1 - 0.0053 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX25959.1 - 0.016 15.3 0.5 0.063 13.4 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAX25959.1 - 0.018 15.4 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 GAX25959.1 - 0.034 14.7 0.1 0.083 13.5 0.1 1.9 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX25959.1 - 0.44 10.6 3.5 14 5.8 0.0 3.0 3 1 0 3 3 3 0 Ubiquitin-like domain Sod_Fe_C PF02777.18 GAX25960.1 - 1.8e-34 118.0 0.0 2.8e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAX25960.1 - 2.6e-32 111.1 0.2 4.4e-32 110.4 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Phasin_2 PF09361.10 GAX25960.1 - 0.17 12.1 0.3 9.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Phasin protein MFS_1 PF07690.16 GAX25961.1 - 7.7e-19 67.8 40.2 2.5e-12 46.4 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAX25961.1 - 1.4e-07 30.8 11.0 2.9e-07 29.7 11.0 1.5 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAX25962.1 - 4.4e-23 81.8 30.5 5.2e-17 61.8 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAX25962.1 - 0.0013 17.7 16.4 0.018 13.9 16.2 2.5 1 1 0 1 1 1 1 MFS_1 like family DUF2470 PF10615.9 GAX25963.1 - 4.2e-08 33.7 0.0 6.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 GAX25963.1 - 0.0044 17.3 0.6 0.012 15.9 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Aldedh PF00171.22 GAX25965.1 - 8.1e-43 146.6 0.0 9.9e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CTP_transf_1 PF01148.20 GAX25966.1 - 5e-62 210.1 13.4 7.8e-62 209.4 13.4 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family DUF1731 PF08338.11 GAX25967.1 - 1.2e-16 60.3 0.1 2.3e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 GAX25967.1 - 9.6e-07 28.5 0.0 6.7e-05 22.5 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF5300 PF17224.3 GAX25967.1 - 0.086 13.1 0.1 4.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) 3Beta_HSD PF01073.19 GAX25967.1 - 0.12 11.4 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RNA_POL_M_15KD PF02150.16 GAX25968.1 - 4.6e-09 36.0 0.9 4.6e-09 36.0 0.9 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 GAX25968.1 - 4.4e-06 26.4 3.7 4.4e-06 26.4 3.7 2.2 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) DUF3268 PF11672.8 GAX25968.1 - 0.49 10.7 4.4 1.3 9.4 1.2 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain DUF4149 PF13664.6 GAX25969.1 - 1.5e-26 92.6 4.9 1.5e-26 92.6 4.9 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 GAX25969.1 - 0.011 16.1 6.0 0.48 10.7 6.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) AzlD PF05437.12 GAX25969.1 - 0.02 15.1 0.7 0.02 15.1 0.7 2.7 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) WD40 PF00400.32 GAX25970.1 - 1e-21 76.8 16.6 0.00011 22.9 0.1 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX25970.1 - 5.2e-07 29.9 0.7 0.15 12.4 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX25970.1 - 0.0027 17.1 0.0 0.067 12.5 0.0 2.7 3 0 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 GAX25970.1 - 0.046 12.2 0.0 0.13 10.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome D1 heme domain PPR_2 PF13041.6 GAX25971.1 - 5e-34 116.3 13.0 0.00014 21.9 0.1 11.6 7 4 4 11 11 11 9 PPR repeat family PPR_1 PF12854.7 GAX25971.1 - 1.3e-26 92.0 6.8 0.12 12.1 0.0 13.6 15 1 0 15 15 15 9 PPR repeat PPR_3 PF13812.6 GAX25971.1 - 1.3e-22 79.7 2.5 0.067 13.3 0.0 10.3 8 3 4 12 12 12 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX25971.1 - 3.3e-08 33.2 18.4 0.001 18.5 0.1 5.6 1 1 6 7 7 7 5 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAX25971.1 - 5.3e-06 26.3 40.1 2.4 8.6 0.0 14.3 16 2 0 16 16 16 3 PPR repeat Annexin_like PF18411.1 GAX25971.1 - 0.18 12.1 1.8 14 6.0 0.1 3.6 2 1 1 3 3 3 0 Annexin-like domain DUF1325 PF07039.11 GAX25972.1 - 4.8e-15 55.8 0.0 1.4e-13 51.1 0.0 2.4 2 0 0 2 2 2 1 SGF29 tudor-like domain V-SNARE_C PF12352.8 GAX25973.1 - 1.3e-08 35.0 1.5 3.9e-08 33.5 0.1 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Fascin PF06268.13 GAX25973.1 - 0.00037 20.7 0.1 0.0011 19.2 0.1 1.8 1 0 0 1 1 1 1 Fascin domain Synaptobrevin PF00957.21 GAX25973.1 - 0.01 15.6 5.3 0.026 14.3 0.1 3.1 3 0 0 3 3 3 0 Synaptobrevin Exonuc_VII_L PF02601.15 GAX25973.1 - 4.2 6.8 9.9 0.88 9.1 5.5 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit MtN3_slv PF03083.16 GAX25974.1 - 1.2e-31 108.5 6.8 4e-16 58.8 0.4 2.5 2 1 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Exonuc_VII_L PF02601.15 GAX25975.1 - 0.051 13.1 0.8 0.089 12.4 0.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Herpes_UL25 PF01499.16 GAX25975.1 - 0.4 9.1 4.6 0.61 8.5 4.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Atg14 PF10186.9 GAX25975.1 - 6.9 5.7 8.7 16 4.5 8.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AbfS_sensor PF18225.1 GAX25976.1 - 0.18 11.7 2.8 0.89 9.5 0.1 2.9 3 0 0 3 3 3 0 Sensor histidine kinase (AbfS) sensor domain PT PF04886.12 GAX25978.1 - 0.0096 15.5 9.2 0.029 13.9 9.2 1.9 1 1 0 1 1 1 1 PT repeat Protocadherin PF08374.11 GAX25978.1 - 0.061 13.3 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Oxidored_q2 PF00420.24 GAX25978.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DAP10 PF07213.11 GAX25978.1 - 0.094 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 DAP10 membrane protein DUF4381 PF14316.6 GAX25978.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CEND1 PF15677.5 GAX25978.1 - 0.14 12.7 0.4 0.34 11.5 0.4 1.7 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 HEAT_2 PF13646.6 GAX25979.1 - 5.5e-07 29.9 1.6 0.12 12.8 0.1 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 GAX25979.1 - 0.022 15.0 9.5 17 6.0 0.1 6.3 6 0 0 6 6 6 0 HEAT repeat TFIIB PF00382.19 GAX25979.1 - 0.067 13.3 0.9 7.4 6.7 0.0 3.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat CLASP_N PF12348.8 GAX25979.1 - 0.72 9.4 5.0 0.92 9.0 0.0 3.6 5 0 0 5 5 5 0 CLASP N terminal Chloroa_b-bind PF00504.21 GAX25980.1 - 3e-32 112.4 0.1 4.6e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TauD PF02668.16 GAX25981.1 - 6e-27 95.1 0.0 1.3e-26 94.0 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DNA_repr_REX1B PF14966.6 GAX25981.1 - 0.22 12.2 0.0 0.43 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA repair REX1-B RRM_1 PF00076.22 GAX25982.1 - 3.7e-08 33.1 0.0 8.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 GAX25982.1 - 8.5e-05 23.0 0.0 0.00081 19.8 0.0 2.5 1 1 0 1 1 1 1 SET domain DUF1995 PF09353.10 GAX25983.1 - 9.2e-16 58.5 0.0 1.4e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF1848 PF08902.11 GAX25983.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Dynein_light PF01221.18 GAX25984.1 - 3e-39 133.2 1.6 3.3e-39 133.1 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RNA_pol PF00940.19 GAX25985.1 - 3.9e-149 497.0 0.0 1.2e-148 495.4 0.0 1.8 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 GAX25985.1 - 5.1e-60 203.6 0.6 7.5e-60 203.1 0.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal RNase_J_C PF17770.1 GAX25985.1 - 0.31 12.1 1.4 2.5 9.2 0.1 2.9 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain DUF382 PF04037.13 GAX25986.1 - 2.8e-52 176.2 0.1 2.8e-52 176.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 GAX25986.1 - 5.6e-17 61.3 4.4 1.1e-16 60.4 4.4 1.6 1 0 0 1 1 1 1 PSP RPN2_C PF18004.1 GAX25986.1 - 0.64 9.9 11.8 0.93 9.4 4.2 2.9 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain ADH_zinc_N PF00107.26 GAX25987.1 - 7.8e-24 84.1 0.1 1.3e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX25987.1 - 2.3e-18 66.1 2.5 4.7e-18 65.1 2.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 GAX25987.1 - 0.0024 17.2 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAX25987.1 - 0.0035 16.7 0.9 0.0057 16.0 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAX25987.1 - 0.0059 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 GAX25987.1 - 0.0075 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 GAX25987.1 - 0.048 14.3 0.2 0.091 13.3 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HAGH_C PF16123.5 GAX25988.1 - 1.8e-25 89.2 0.0 2.8e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAX25988.1 - 1.6e-14 54.4 4.2 3.8e-12 46.6 4.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAX25988.1 - 0.0072 15.9 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DTW PF03942.15 GAX25989.1 - 6.3e-12 45.6 0.1 9e-12 45.1 0.1 1.4 1 1 0 1 1 1 1 DTW domain Atg14 PF10186.9 GAX25989.1 - 0.21 10.7 1.4 0.29 10.2 1.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 L_biotic_typeA PF04604.13 GAX25990.1 - 0.014 15.2 0.0 22 5.0 0.0 3.7 4 0 0 4 4 4 0 Type-A lantibiotic DSPc PF00782.20 GAX25991.1 - 2e-15 56.8 0.1 2.5e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAX25991.1 - 0.0028 17.3 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 GAX25991.1 - 0.053 13.2 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 GAX25991.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.14 GAX25991.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain SSB PF00436.25 GAX25992.1 - 1.2e-24 86.3 0.0 1.6e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family RecJ_OB PF17768.1 GAX25992.1 - 0.038 14.2 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 RecJ OB domain zf-CCCH PF00642.24 GAX25993.1 - 1.3e-28 98.3 21.8 7.4e-10 38.5 1.8 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAX25993.1 - 2e-15 56.2 37.1 1.2e-05 25.1 5.6 3.3 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 GAX25993.1 - 2.2e-09 36.9 29.9 0.0027 17.5 5.0 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 GAX25993.1 - 1.2e-07 32.4 7.3 0.013 16.2 0.1 3.4 3 0 0 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 GAX25993.1 - 1.8e-06 28.2 25.4 0.0044 17.5 2.1 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 GAX25993.1 - 1.7 8.9 9.1 22 5.3 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger containing family ParA PF10609.9 GAX25994.1 - 1.2e-64 218.2 0.0 1.6e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAX25994.1 - 5e-10 39.5 0.0 9.7e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAX25994.1 - 6e-09 36.1 0.1 2.6e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 GAX25994.1 - 3.4e-06 26.6 0.0 6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 GAX25994.1 - 2.1e-05 23.9 0.2 0.0073 15.5 0.1 2.7 2 1 1 3 3 3 2 Anion-transporting ATPase VirC1 PF07015.11 GAX25994.1 - 0.0016 17.8 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 GAX25994.1 - 0.012 15.5 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 GAX25994.1 - 0.017 14.1 0.0 0.034 13.1 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 GAX25994.1 - 0.028 13.9 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 GAX25994.1 - 0.055 12.9 0.3 0.39 10.1 0.1 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GAX25994.1 - 0.058 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF971 PF06155.12 GAX25994.1 - 0.1 13.2 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF971) RRF PF01765.19 GAX25995.1 - 3.3e-60 202.7 5.8 9.1e-60 201.3 4.4 1.8 1 1 1 2 2 2 1 Ribosome recycling factor Cyt-b5 PF00173.28 GAX25997.1 - 1.5e-10 41.0 0.0 3.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.7 GAX25997.1 - 0.0092 15.9 0.2 0.02 14.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAX25997.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box domain PI3_PI4_kinase PF00454.27 GAX25998.1 - 3.6e-45 154.7 0.0 4.6e-42 144.6 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAX25998.1 - 6.7e-44 149.5 0.4 4e-43 147.0 0.2 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 GAX25998.1 - 2.7e-05 24.1 0.0 8e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Phosphoinositide 3-kinase C2 Polysacc_deac_1 PF01522.21 GAX25999.1 - 3.2e-13 49.6 0.0 5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase zf-RING_2 PF13639.6 GAX26000.1 - 2.2e-11 43.9 8.4 3.8e-11 43.1 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX26000.1 - 3.5e-11 42.7 3.1 1.7e-10 40.5 2.6 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX26000.1 - 1.1e-07 31.6 7.1 1.8e-07 30.9 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX26000.1 - 1.6e-06 27.9 6.1 3.4e-06 26.8 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX26000.1 - 5.2e-06 26.6 10.1 1.2e-05 25.5 10.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAX26000.1 - 0.00016 21.6 5.5 0.00027 20.9 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX26000.1 - 0.00018 21.5 3.2 0.0003 20.8 3.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX26000.1 - 0.0012 18.4 6.5 0.0023 17.5 6.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GAX26000.1 - 0.0089 16.0 7.6 0.022 14.8 7.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX26000.1 - 0.32 10.9 8.9 0.59 10.0 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAX26000.1 - 0.36 11.0 6.6 0.7 10.1 6.6 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 GAX26000.1 - 0.39 10.9 7.3 2.8 8.2 7.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 GAX26000.1 - 0.75 9.6 6.7 1.4 8.8 6.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 GAX26000.1 - 6.1 6.8 8.7 12 5.9 8.7 1.5 1 0 0 1 1 1 0 PHD-finger Abhydrolase_2 PF02230.16 GAX26001.1 - 4.6e-37 127.9 0.0 5.4e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAX26001.1 - 2.9e-06 28.1 0.0 3.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAX26001.1 - 3.4e-05 23.5 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.25 GAX26001.1 - 0.00014 21.7 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.9 GAX26001.1 - 0.00023 20.8 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 GAX26001.1 - 0.00056 19.8 0.0 0.0014 18.5 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX26001.1 - 0.00064 19.2 0.0 0.79 9.2 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 GAX26001.1 - 0.00072 19.3 0.0 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 Putative esterase DUF2974 PF11187.8 GAX26001.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.12 GAX26001.1 - 0.0044 15.7 0.0 0.006 15.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 GAX26001.1 - 0.0056 16.3 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX26001.1 - 0.0089 15.3 0.0 0.025 13.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 GAX26001.1 - 0.015 15.3 0.0 0.036 14.0 0.0 1.6 2 0 0 2 2 2 0 Cutinase FSH1 PF03959.13 GAX26001.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF3341 PF11821.8 GAX26001.1 - 0.055 13.1 0.0 9.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) PAF-AH_p_II PF03403.13 GAX26001.1 - 0.072 11.6 0.0 0.27 9.7 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II HMG_box PF00505.19 GAX26002.1 - 1.3e-17 64.0 16.8 2.3e-09 37.5 8.3 4.3 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX26002.1 - 6.1e-17 62.0 10.6 3.3e-09 37.2 4.5 3.7 2 1 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 GAX26002.1 - 0.0087 16.0 0.8 0.046 13.7 0.8 2.2 1 0 0 1 1 1 1 HMG (high mobility group) box 5 SKI PF01202.22 GAX26003.1 - 6.5e-44 149.8 0.0 8e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 GAX26003.1 - 2.1e-06 28.0 0.0 1.8e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX26003.1 - 6.9e-05 23.4 0.0 0.00018 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAX26003.1 - 0.001 19.5 0.2 0.017 15.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 GAX26003.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA PF00004.29 GAX26003.1 - 0.0066 16.9 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CTP_transf_3 PF02348.19 GAX26003.1 - 0.012 15.5 0.1 0.054 13.4 0.0 1.9 2 0 0 2 2 2 0 Cytidylyltransferase dNK PF01712.19 GAX26003.1 - 0.025 14.4 0.1 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_16 PF13191.6 GAX26003.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 GAX26003.1 - 0.17 11.5 0.1 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase DUF2985 PF11204.8 GAX26004.1 - 0.27 11.4 0.0 0.27 11.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) Pro_isomerase PF00160.21 GAX26005.1 - 2.5e-48 164.3 0.1 4.2e-48 163.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 GAX26005.1 - 1e-31 109.1 0.0 2.8e-31 107.7 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 GAX26005.1 - 2e-08 33.7 3.9 0.087 13.0 0.5 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX26005.1 - 1.9e-07 30.6 1.6 0.0092 15.8 0.3 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX26005.1 - 1.2e-06 28.5 0.2 1.2e-06 28.5 0.2 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX26005.1 - 4.8e-05 23.6 0.4 0.054 13.8 0.0 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX26005.1 - 0.00044 20.3 1.8 0.0067 16.6 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX26005.1 - 0.004 17.8 0.5 4.5 8.0 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX26005.1 - 0.0078 15.9 0.6 6.7 6.5 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 GAX26005.1 - 0.017 15.6 2.4 2 9.0 0.0 3.0 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX26005.1 - 0.027 15.1 4.6 5.7 7.8 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat UvrD_C PF13361.6 GAX26006.1 - 2.8e-54 184.8 0.0 9.4e-54 183.1 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 GAX26006.1 - 3.5e-38 131.9 1.3 1.3e-37 130.0 0.1 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 GAX26006.1 - 5e-12 46.4 0.0 1.4e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 GAX26006.1 - 2.6e-09 36.7 0.1 1.2e-08 34.6 0.1 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 GAX26006.1 - 4e-05 23.5 0.0 0.0056 16.5 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 GAX26006.1 - 6e-05 22.8 0.1 0.046 13.3 0.0 3.5 2 1 0 2 2 2 2 AAA domain CRAL_TRIO PF00650.20 GAX26007.1 - 2.6e-21 76.0 0.0 3.6e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX26007.1 - 3.6e-05 23.9 0.0 0.0001 22.5 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain PPR_2 PF13041.6 GAX26008.1 - 3.5e-05 23.9 0.0 0.0058 16.8 0.0 3.7 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.20 GAX26008.1 - 0.00026 21.0 0.5 0.49 10.8 0.0 5.7 7 0 0 7 7 7 1 PPR repeat TPR_16 PF13432.6 GAX26008.1 - 0.09 13.4 2.2 7.4 7.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CRAL_TRIO PF00650.20 GAX26009.1 - 9.4e-13 48.2 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX26009.1 - 5.7e-05 23.3 0.1 0.0001 22.5 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SGL PF08450.12 GAX26010.1 - 1.9e-52 178.3 0.1 2.3e-52 178.0 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 GAX26010.1 - 0.01 15.9 0.1 0.47 10.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) MatE PF01554.18 GAX26011.1 - 2.3e-33 115.1 30.8 1.7e-21 76.5 11.0 2.9 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAX26011.1 - 6.1e-06 26.4 9.2 6.1e-06 26.4 9.2 3.2 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MMR_HSR1 PF01926.23 GAX26013.1 - 8e-09 35.6 0.0 4.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX26013.1 - 1.9e-05 24.6 0.0 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 GAX26013.1 - 0.0045 16.5 0.0 0.23 11.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX26013.1 - 0.0058 16.7 1.2 0.015 15.4 0.0 2.3 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 GAX26013.1 - 0.0063 16.1 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 GAX26013.1 - 0.041 13.0 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 GAX26013.1 - 0.056 13.9 0.0 0.25 11.9 0.0 2.1 1 0 0 1 1 1 0 ABC transporter MT0933_antitox PF14013.6 GAX26013.1 - 0.086 13.2 2.4 6.2 7.2 0.1 2.9 3 0 0 3 3 3 0 MT0933-like antitoxin protein Roc PF08477.13 GAX26013.1 - 0.13 12.4 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 GAX26013.1 - 0.14 12.0 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Cyclin_N PF00134.23 GAX26014.1 - 1.4e-15 57.1 0.0 2.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX26014.1 - 0.0019 18.3 0.4 0.006 16.7 0.1 2.0 2 1 1 3 3 3 1 Cyclin, C-terminal domain Rep_fac_C PF08542.11 GAX26015.1 - 2.8e-23 82.1 0.0 1.6e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 GAX26015.1 - 9.9e-16 58.4 0.0 1.7e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAX26015.1 - 1.2e-10 41.4 0.1 5.1e-08 32.9 0.3 2.8 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 GAX26015.1 - 2.6e-07 31.2 0.1 0.00014 22.3 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX26015.1 - 8.1e-07 29.4 0.2 0.0015 18.8 0.1 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 GAX26015.1 - 1.2e-06 28.6 0.0 2.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 GAX26015.1 - 1.7e-06 28.1 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAX26015.1 - 2e-05 24.1 0.0 0.00036 20.0 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAX26015.1 - 6.2e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAX26015.1 - 8.1e-05 22.6 0.0 0.00021 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAX26015.1 - 8.6e-05 22.4 0.0 0.00028 20.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 GAX26015.1 - 0.00012 22.4 0.0 0.0004 20.7 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 GAX26015.1 - 0.00024 20.9 0.1 0.0004 20.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 GAX26015.1 - 0.00031 20.5 0.0 0.00095 18.9 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 GAX26015.1 - 0.00042 20.1 0.0 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 GAX26015.1 - 0.0005 20.6 0.0 0.00081 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAX26015.1 - 0.00051 20.2 0.2 0.0025 18.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 GAX26015.1 - 0.00054 20.0 0.0 1.5 8.8 0.0 2.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 GAX26015.1 - 0.0011 19.4 0.0 0.0033 17.8 0.0 2.0 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 GAX26015.1 - 0.0022 17.7 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.6 GAX26015.1 - 0.0024 18.2 0.4 0.029 14.7 0.1 2.3 2 1 1 3 3 2 1 AAA domain KTI12 PF08433.10 GAX26015.1 - 0.0025 17.3 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.15 GAX26015.1 - 0.0027 17.6 0.1 0.052 13.4 0.0 2.5 2 1 0 3 3 2 1 NTPase MeaB PF03308.16 GAX26015.1 - 0.0032 16.5 0.0 0.0061 15.6 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 GAX26015.1 - 0.0035 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAX26015.1 - 0.0041 16.6 0.0 0.0079 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 GAX26015.1 - 0.0042 16.5 0.0 0.21 11.0 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein MCM PF00493.23 GAX26015.1 - 0.005 16.0 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_24 PF13479.6 GAX26015.1 - 0.0079 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAX26015.1 - 0.0083 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 GAX26015.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX26015.1 - 0.03 13.7 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DEAD PF00270.29 GAX26015.1 - 0.032 14.0 0.1 0.98 9.2 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.22 GAX26015.1 - 0.056 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 GAX26015.1 - 0.075 12.6 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAX26015.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 GAX26015.1 - 0.082 12.8 0.1 0.67 9.9 0.1 2.1 1 1 0 1 1 1 0 NACHT domain Psm4 PF17063.5 GAX26015.1 - 3 8.7 5.3 1.2 9.9 0.1 2.9 3 0 0 3 3 2 0 Phenol-soluble modulin alpha 4 peptide HSP20 PF00011.21 GAX26017.1 - 6.6e-17 61.5 0.4 9e-17 61.1 0.4 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAX26017.1 - 0.03 13.9 0.4 0.061 12.9 0.4 1.6 1 1 0 1 1 1 0 HSP20-like domain found in ArsA MA3 PF02847.17 GAX26018.1 - 2.6e-19 69.3 1.4 9.5e-19 67.5 1.4 2.0 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 GAX26018.1 - 9.1e-13 48.3 1.1 2.3e-12 47.0 0.1 2.3 3 1 0 3 3 3 1 MIF4G domain Octopine_DH PF02317.17 GAX26018.1 - 0.26 11.4 2.2 27 4.8 0.1 3.4 4 0 0 4 4 4 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain PKcGMP_CC PF16808.5 GAX26018.1 - 4 7.4 7.8 4.3 7.3 0.3 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YbaB_DNA_bd PF02575.16 GAX26019.1 - 5.5e-08 32.9 0.4 4.9e-07 29.9 0.4 2.0 1 1 0 1 1 1 1 YbaB/EbfC DNA-binding family Ycf1 PF05758.12 GAX26019.1 - 0.097 10.5 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 Ycf1 tRNA-synt_2 PF00152.20 GAX26020.1 - 1.2e-79 267.7 0.1 1.5e-79 267.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX26020.1 - 6.2e-14 51.8 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX26020.1 - 3.3e-07 30.0 0.0 0.0024 17.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) JAB PF01398.21 GAX26021.1 - 3.9e-11 43.0 0.2 1e-10 41.6 0.2 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HNH_3 PF13392.6 GAX26022.1 - 1.1e-05 25.1 0.5 0.053 13.3 0.0 2.6 2 0 0 2 2 2 2 HNH endonuclease NUMOD4 PF07463.11 GAX26022.1 - 0.095 12.9 1.9 2.8 8.2 0.5 2.7 2 0 0 2 2 2 0 NUMOD4 motif LysE PF01810.18 GAX26022.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 LysE type translocator Allantoicase PF03561.15 GAX26023.1 - 1.3e-82 274.9 0.0 1.4e-41 141.8 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 GAX26023.1 - 0.091 12.9 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 F5/8 type C domain EMP24_GP25L PF01105.24 GAX26024.1 - 1e-19 71.2 0.8 5.4e-15 55.8 1.0 2.1 2 0 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Sec20 PF03908.13 GAX26024.1 - 0.19 11.6 2.2 0.25 11.3 0.9 1.8 2 0 0 2 2 2 0 Sec20 MFS_1 PF07690.16 GAX26025.1 - 1e-13 51.0 20.9 1e-13 51.0 20.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 GAX26025.1 - 0.0051 15.6 0.1 0.0051 15.6 0.1 2.2 3 0 0 3 3 3 1 Reduced folate carrier Pkinase PF00069.25 GAX26027.1 - 5.2e-35 121.1 0.0 9.8e-26 90.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26027.1 - 1.9e-19 70.0 0.0 1.8e-18 66.8 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX26027.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RRS1 PF04939.12 GAX26028.1 - 2e-39 135.0 7.5 2.3e-38 131.6 4.9 2.8 1 1 1 2 2 2 2 Ribosome biogenesis regulatory protein (RRS1) Cid2 PF09774.9 GAX26028.1 - 0.039 14.4 1.0 0.039 14.4 1.0 2.2 2 1 0 2 2 2 0 Caffeine-induced death protein 2 SH3BGR PF04908.15 GAX26029.1 - 0.0001 22.4 0.0 0.00015 21.9 0.0 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 GAX26029.1 - 0.0056 16.9 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Radical_SAM PF04055.21 GAX26030.1 - 9.3e-17 61.9 0.0 1.8e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 GAX26030.1 - 3.2e-10 40.4 0.1 9.5e-10 38.9 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family DnaJ_C PF01556.18 GAX26031.1 - 1.7e-34 119.0 0.0 2.4e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX26031.1 - 6.4e-25 87.1 2.9 1.1e-24 86.3 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAX26031.1 - 0.00012 22.3 2.4 0.00026 21.3 2.4 1.5 1 0 0 1 1 1 1 DnaJ central domain TB PF00683.17 GAX26031.1 - 0.022 14.5 0.5 0.047 13.4 0.5 1.5 1 0 0 1 1 1 0 TB domain DAGAT PF03982.13 GAX26033.1 - 2.4e-28 98.9 0.0 4.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase GerD PF17898.1 GAX26033.1 - 2.4e-07 30.7 27.5 0.00014 21.8 5.8 2.5 1 1 0 2 2 2 2 Spore germination GerD central core domain Ins_allergen_rp PF06757.13 GAX26033.1 - 0.00046 20.2 3.1 1 9.3 0.5 3.1 3 0 0 3 3 3 2 Insect allergen related repeat, nitrile-specifier detoxification PGAP1 PF07819.13 GAX26033.1 - 0.023 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein RPN13_C PF16550.5 GAX26033.1 - 0.024 14.8 10.1 0.35 11.0 1.6 2.5 1 1 1 2 2 2 0 UCH-binding domain STI1 PF17830.1 GAX26033.1 - 0.03 14.2 31.4 0.015 15.3 8.3 4.0 2 2 1 3 3 3 0 STI1 domain Chlorophyllase2 PF12740.7 GAX26033.1 - 0.038 12.9 0.9 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 GAX26033.1 - 0.078 13.6 5.4 0.13 12.8 4.3 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAX26033.1 - 0.1 12.4 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Nif11 PF07862.11 GAX26033.1 - 0.12 12.6 6.7 4.5 7.6 0.1 3.9 2 2 1 3 3 3 0 Nif11 domain Lipase_3 PF01764.25 GAX26033.1 - 0.15 11.9 0.0 0.51 10.2 0.0 1.9 1 0 0 1 1 1 0 Lipase (class 3) PTS_EIIA_2 PF00359.22 GAX26033.1 - 0.18 11.7 0.9 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF1310 PF07006.11 GAX26033.1 - 0.24 11.4 3.6 0.38 10.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) ParE-like_toxin PF15781.5 GAX26033.1 - 1.1 9.2 4.5 18 5.3 0.2 2.5 2 0 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system His_Phos_1 PF00300.22 GAX26034.1 - 5.4e-09 36.0 3.0 6.3e-08 32.6 3.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PMBR PF09373.10 GAX26035.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein-binding repeat Remorin_C PF03763.13 GAX26038.1 - 0.084 12.8 4.4 0.06 13.2 0.9 2.2 2 0 0 2 2 2 0 Remorin, C-terminal region HSBP1 PF06825.12 GAX26038.1 - 2.4 8.1 7.1 4.1 7.3 6.2 1.8 1 1 1 2 2 2 0 Heat shock factor binding protein 1 zf-CCCH_4 PF18044.1 GAX26039.1 - 7.2e-08 32.1 4.0 1.3e-07 31.2 4.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAX26039.1 - 7.7e-08 32.1 4.1 1.5e-07 31.2 4.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAX26039.1 - 7.9e-08 32.0 2.4 1.9e-07 30.8 2.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NUFIP1 PF10453.9 GAX26039.1 - 1.4e-07 31.2 0.7 3.4e-07 30.0 0.7 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Torus PF16131.5 GAX26039.1 - 1.4e-05 25.8 0.0 2.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 GAX26039.1 - 0.052 14.0 3.1 0.052 14.0 3.1 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger GILT PF03227.16 GAX26040.1 - 1.2e-21 76.9 0.2 2.6e-21 75.9 0.2 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) SelR PF01641.18 GAX26042.1 - 0.0077 16.3 0.2 0.026 14.6 0.2 2.0 1 1 0 1 1 1 1 SelR domain FCP1_C PF09309.10 GAX26042.1 - 0.017 15.1 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Popeye PF04831.13 GAX26044.1 - 1.1e-06 28.8 0.1 1.9e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 GAX26044.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1241 PF06840.11 GAX26044.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) SurA_N_3 PF13624.6 GAX26044.1 - 0.21 11.4 1.6 0.77 9.5 0.1 2.4 2 1 1 3 3 3 0 SurA N-terminal domain Response_reg PF00072.24 GAX26045.1 - 3.3e-22 78.8 0.0 8.4e-22 77.5 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 GAX26045.1 - 0.00026 20.5 0.5 0.00074 19.0 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 GAX26045.1 - 0.0033 17.1 0.0 0.012 15.4 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 GAX26045.1 - 0.024 14.7 0.3 0.15 12.1 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Bestrophin PF01062.21 GAX26046.1 - 2e-21 76.7 0.1 2.7e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RBFA PF02033.18 GAX26047.1 - 9.2e-16 58.2 0.2 1.2e-15 57.8 0.2 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A DUF1170 PF06663.13 GAX26047.1 - 0.041 13.6 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) CcmE PF03100.15 GAX26047.1 - 0.057 13.4 0.1 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 CcmE Proteasome PF00227.26 GAX26048.1 - 2.8e-49 167.2 0.4 3.5e-49 166.9 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Acyl_transf_3 PF01757.22 GAX26049.1 - 4.9e-21 75.2 37.8 5.8e-21 74.9 33.7 2.4 2 1 0 2 2 2 1 Acyltransferase family DUF3792 PF12670.7 GAX26049.1 - 1 9.6 9.1 5.6 7.2 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) ABC1 PF03109.16 GAX26050.1 - 1.4e-22 80.1 0.0 5e-22 78.3 0.0 2.0 1 1 0 1 1 1 1 ABC1 family APH PF01636.23 GAX26050.1 - 0.00081 19.4 0.4 0.0075 16.2 0.1 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX26050.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF3730 PF12530.8 GAX26050.1 - 0.09 12.3 0.1 0.19 11.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3730) Proteasome PF00227.26 GAX26051.1 - 2.1e-22 79.5 0.0 3.3e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX26051.1 - 2.4e-08 33.5 0.0 7.1e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SpoU_methylase PF00588.19 GAX26052.1 - 3.7e-14 53.1 0.0 1.5e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family UPF0020 PF01170.18 GAX26055.1 - 4.8e-13 49.2 0.0 1.7e-10 40.9 0.1 3.3 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 GAX26055.1 - 0.0016 18.2 0.2 0.05 13.3 0.0 2.4 2 1 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.15 GAX26055.1 - 0.0085 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MethyltransfD12 PF02086.15 GAX26055.1 - 0.082 12.6 0.3 0.75 9.4 0.0 2.2 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase AAA_22 PF13401.6 GAX26056.1 - 5.1e-07 30.0 0.0 0.00011 22.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX26056.1 - 9.5e-07 29.4 0.0 1.8e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAX26056.1 - 0.0027 18.1 0.0 0.12 12.8 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAX26056.1 - 0.0028 17.6 0.0 0.0083 16.1 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 GAX26056.1 - 0.0038 17.6 0.0 0.0083 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAX26056.1 - 0.0046 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 GAX26056.1 - 0.014 15.2 0.0 0.037 13.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein Sigma54_activat PF00158.26 GAX26056.1 - 0.031 14.0 0.0 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 GAX26056.1 - 0.034 13.9 0.1 0.075 12.8 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 GAX26056.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 GAX26056.1 - 0.065 13.1 0.0 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 GAX26056.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAX26056.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 GAX26056.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Fer4_13 PF13370.6 GAX26057.1 - 1.5e-10 41.4 4.2 5e-10 39.8 4.2 2.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 GAX26057.1 - 6.5e-08 33.2 4.3 4e-07 30.7 4.3 2.3 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_10 PF13237.6 GAX26057.1 - 0.00048 20.2 1.6 0.00048 20.2 1.6 2.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAX26057.1 - 0.004 17.2 0.8 0.004 17.2 0.8 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4 PF00037.27 GAX26057.1 - 0.0051 16.6 1.3 0.0051 16.6 1.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 GAX26057.1 - 0.0095 16.0 3.2 0.0095 16.0 3.2 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAX26057.1 - 0.02 15.0 0.5 0.02 15.0 0.5 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_9 PF13187.6 GAX26057.1 - 0.086 13.0 0.2 0.086 13.0 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 GAX26057.1 - 0.31 11.7 9.3 0.74 10.4 0.9 3.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_26 PF13500.6 GAX26058.1 - 9.7e-14 51.7 0.0 6.6e-13 48.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX26058.1 - 0.097 12.7 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PSI PF01437.25 GAX26059.1 - 0.0012 19.3 37.9 0.081 13.5 17.3 2.7 1 1 1 2 2 2 2 Plexin repeat PSI_integrin PF17205.3 GAX26059.1 - 0.022 14.5 30.2 0.053 13.3 10.0 2.6 2 0 0 2 2 2 0 Integrin plexin domain LEA_2 PF03168.13 GAX26059.1 - 0.086 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein DTW PF03942.15 GAX26060.1 - 5.3e-26 91.5 0.5 8.6e-26 90.9 0.5 1.3 1 0 0 1 1 1 1 DTW domain FlxA PF14282.6 GAX26061.1 - 0.013 15.5 0.7 0.013 15.5 0.7 3.0 2 1 0 2 2 2 0 FlxA-like protein PilJ PF13675.6 GAX26061.1 - 0.033 14.2 3.7 0.65 10.0 0.3 2.6 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term GAIN_A PF18619.1 GAX26061.1 - 0.046 13.9 0.1 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF1450 PF07293.11 GAX26061.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) DUF948 PF06103.11 GAX26061.1 - 0.087 13.1 2.4 0.28 11.5 0.3 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HEPN_RES_NTD1 PF18870.1 GAX26061.1 - 0.098 12.9 0.3 0.24 11.6 0.3 1.6 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 RVT_N PF13655.6 GAX26061.1 - 0.28 11.5 3.1 0.27 11.5 0.7 2.3 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase DUF572 PF04502.13 GAX26061.1 - 0.5 9.9 11.6 0.79 9.3 11.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) NPV_P10 PF05531.12 GAX26061.1 - 0.75 10.3 7.4 0.49 10.9 1.8 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CorA PF01544.18 GAX26061.1 - 3.6 6.8 5.4 0.59 9.4 0.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Spc7 PF08317.11 GAX26061.1 - 6.3 5.6 17.7 7.6 5.3 14.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1115 PF06544.12 GAX26062.1 - 2.9e-10 40.4 0.0 8.9e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 GAX26062.1 - 0.007 16.6 0.0 0.02 15.2 0.0 1.8 1 1 0 1 1 1 1 RWD domain Baculo_PEP_C PF04513.12 GAX26063.1 - 8.8e-07 29.0 9.7 2e-06 27.9 4.2 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 GAX26063.1 - 0.0049 16.2 0.0 0.021 14.2 0.0 1.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 GAX26063.1 - 0.014 15.9 1.5 0.94 10.0 0.0 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CHASE3 PF05227.13 GAX26063.1 - 0.071 13.0 0.3 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 CHASE3 domain Rsd_AlgQ PF04353.13 GAX26063.1 - 0.12 12.3 2.3 9.9 6.1 0.2 2.6 1 1 2 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ UPF0184 PF03670.13 GAX26063.1 - 0.13 12.7 0.8 1.2 9.6 0.1 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) DUF1995 PF09353.10 GAX26064.1 - 1e-22 81.2 0.0 1.4e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Sacchrp_dh_NADP PF03435.18 GAX26065.1 - 4.3e-11 43.2 0.0 7.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAX26065.1 - 2.7e-05 23.8 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX26065.1 - 2.9e-05 24.1 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAX26065.1 - 6.9e-05 22.0 0.0 0.00015 20.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAX26065.1 - 0.00089 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAX26065.1 - 0.01 15.4 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_7 PF13241.6 GAX26065.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DapB_N PF01113.20 GAX26065.1 - 0.038 14.1 0.3 0.39 10.9 0.3 2.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 GAX26065.1 - 0.039 13.9 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF2855 PF11017.8 GAX26065.1 - 0.15 11.8 0.1 0.31 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) Shikimate_DH PF01488.20 GAX26065.1 - 0.17 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RRM_1 PF00076.22 GAX26066.1 - 0.0076 16.0 0.1 0.032 14.0 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_2 PF00797.17 GAX26067.1 - 4.1e-36 125.0 0.0 5.3e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase UPF0515 PF15135.6 GAX26069.1 - 0.044 13.1 0.4 0.058 12.7 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Porin_3 PF01459.22 GAX26070.1 - 1.1e-21 77.6 0.7 1.2e-21 77.4 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin SKN1 PF03935.15 GAX26071.1 - 4.4e-73 246.4 11.5 2.6e-61 207.6 9.1 3.9 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAX26071.1 - 1.8e-06 27.6 0.3 0.055 12.9 0.1 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 EGF_2 PF07974.13 GAX26071.1 - 0.00037 20.8 12.1 0.00037 20.8 12.1 2.9 2 1 0 2 2 2 1 EGF-like domain Gly-zipper_Omp PF13488.6 GAX26071.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycine zipper Glu_cyclase_2 PF05096.12 GAX26072.1 - 1.3e-70 237.7 0.2 1.7e-70 237.4 0.2 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase HMG_box PF00505.19 GAX26073.1 - 8.4e-13 48.5 4.0 2e-07 31.3 0.5 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX26073.1 - 2.1e-12 47.4 3.7 1.5e-07 31.9 0.6 2.4 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.13 GAX26073.1 - 0.021 15.4 1.8 0.021 15.4 1.8 1.7 1 1 0 2 2 2 0 YABBY protein GET2 PF08690.10 GAX26073.1 - 0.95 9.1 5.1 1.3 8.7 5.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 ATG101 PF07855.12 GAX26074.1 - 5.1e-39 133.8 0.0 6.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 PhyH PF05721.13 GAX26075.1 - 0.00014 22.2 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 53-BP1_Tudor PF09038.10 GAX26075.1 - 0.18 11.8 0.2 0.42 10.6 0.2 1.6 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Gcd10p PF04189.13 GAX26077.1 - 2.6e-55 187.6 0.0 3.9e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family RE_MamI PF09567.10 GAX26079.1 - 0.18 11.4 0.1 0.84 9.3 0.1 1.9 2 0 0 2 2 2 0 MamI restriction endonuclease DUF3833 PF12915.7 GAX26080.1 - 0.087 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) Ribosomal_L18 PF17135.4 GAX26081.1 - 4.3e-79 264.3 2.9 4.8e-79 264.1 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAX26081.1 - 0.00066 20.3 0.0 0.0012 19.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1737 PF08410.10 GAX26081.1 - 0.09 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Nudc_N PF14050.6 GAX26081.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.7 1 1 0 1 1 1 0 N-terminal conserved domain of Nudc. NMD3 PF04981.13 GAX26082.1 - 1.9e-72 243.7 4.8 3.1e-72 243.0 4.8 1.3 1 0 0 1 1 1 1 NMD3 family C1_4 PF07975.12 GAX26082.1 - 7.5 6.9 7.5 19 5.6 0.4 3.6 3 0 0 3 3 3 0 TFIIH C1-like domain Ank_2 PF12796.7 GAX26083.1 - 0.0062 17.1 0.0 0.025 15.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) F-box PF00646.33 GAX26083.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain Cyclin_N PF00134.23 GAX26083.1 - 0.15 11.8 0.0 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain F-box-like PF12937.7 GAX26083.1 - 0.2 11.6 0.5 0.49 10.3 0.5 1.7 1 0 0 1 1 1 0 F-box-like Internalin_N PF12354.8 GAX26086.1 - 0.13 12.4 0.1 0.44 10.7 0.1 1.9 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal IQ PF00612.27 GAX26087.1 - 1.3e-38 127.1 187.2 0.00094 18.8 0.5 30.8 31 1 1 32 32 32 23 IQ calmodulin-binding motif CH PF00307.31 GAX26087.1 - 1.2e-09 38.3 0.0 0.00054 20.1 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAX26087.1 - 1.3e-06 28.2 0.0 9.3e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 CAMSAP CH domain PYC_OADA PF02436.18 GAX26087.1 - 0.094 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain NtA PF03146.15 GAX26087.1 - 1.9 8.4 4.7 3 7.8 0.1 3.2 3 0 0 3 3 3 0 Agrin NtA domain UQ_con PF00179.26 GAX26089.1 - 4.5e-25 87.9 0.1 1.4e-24 86.3 0.0 1.9 3 0 0 3 3 3 1 Ubiquitin-conjugating enzyme UEV PF05743.13 GAX26089.1 - 0.00045 20.1 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 2 UEV domain TFIIB_C_1 PF18542.1 GAX26089.1 - 0.084 12.9 0.2 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 Sec7 PF01369.20 GAX26090.1 - 8.9e-68 227.6 0.0 1.7e-67 226.6 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAX26090.1 - 5e-35 120.8 3.0 5e-35 120.8 3.0 3.1 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAX26090.1 - 4.6e-17 61.6 0.0 3.3e-15 55.7 0.0 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1981) DCB PF16213.5 GAX26090.1 - 7.4e-05 22.5 3.0 8.8e-05 22.2 0.1 2.7 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 FIST_C PF10442.9 GAX26094.1 - 8.9e-12 45.1 0.2 1.5e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 FIST C domain Sirohm_synth_M PF14824.6 GAX26094.1 - 0.046 13.2 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central FIST_C PF10442.9 GAX26095.1 - 3.5e-12 46.4 0.2 9.4e-11 41.8 0.0 2.6 2 0 0 2 2 2 1 FIST C domain F-box PF00646.33 GAX26095.1 - 0.0017 18.2 0.1 0.013 15.3 0.1 2.3 2 0 0 2 2 2 1 F-box domain Sirohm_synth_M PF14824.6 GAX26095.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Sec7 PF01369.20 GAX26099.1 - 1e-67 227.4 0.0 2e-67 226.4 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAX26099.1 - 3.4e-35 121.3 9.2 5e-35 120.7 3.7 3.1 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAX26099.1 - 4e-17 61.8 0.2 5.1e-15 55.1 0.1 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1981) DCB PF16213.5 GAX26099.1 - 1.6e-05 24.6 0.9 8.4e-05 22.3 0.1 2.5 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 UQ_con PF00179.26 GAX26100.1 - 4.9e-25 87.8 0.5 2.8e-24 85.4 0.0 2.3 2 1 1 3 3 3 1 Ubiquitin-conjugating enzyme UEV PF05743.13 GAX26100.1 - 0.00015 21.6 0.4 0.093 12.6 0.0 2.7 3 0 0 3 3 3 2 UEV domain DUF2448 PF10476.9 GAX26100.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) IQ PF00612.27 GAX26102.1 - 7e-43 140.4 162.0 0.00092 18.8 0.3 26.8 27 0 0 27 27 27 21 IQ calmodulin-binding motif CH PF00307.31 GAX26102.1 - 1.6e-11 44.3 0.0 8.5e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAX26102.1 - 5.3e-08 32.6 0.0 7.4e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 CAMSAP CH domain PYC_OADA PF02436.18 GAX26102.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain Ricin_B_lectin PF00652.22 GAX26104.1 - 0.0016 18.6 0.2 0.0055 17.0 0.2 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain WAP PF00095.21 GAX26104.1 - 0.31 11.4 13.7 0.77 10.2 1.0 3.5 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' TALPID3 PF15324.6 GAX26104.1 - 0.52 7.9 7.1 0.69 7.5 7.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF3446 PF11928.8 GAX26104.1 - 0.84 10.0 0.0 0.84 10.0 0.0 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain PT PF04886.12 GAX26104.1 - 1.4 8.5 19.8 25 4.5 19.8 2.7 1 1 0 1 1 1 0 PT repeat CarbpepA_inh PF02977.15 GAX26104.1 - 2.3 8.1 12.9 4.2 7.2 2.1 3.1 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Ricin_B_lectin PF00652.22 GAX26105.1 - 3.9e-07 30.4 13.5 6.3e-05 23.2 4.1 2.7 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 GAX26105.1 - 0.0002 21.0 0.7 0.003 17.1 0.3 2.2 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain Ricin_B_lectin PF00652.22 GAX26106.1 - 7.8e-07 29.4 1.9 7.2e-05 23.0 0.2 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 GAX26106.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain DX PF01666.17 GAX26106.1 - 0.016 15.7 7.7 0.058 13.9 0.9 2.9 2 0 0 2 2 2 0 DX module YiiD_C PF09500.10 GAX26106.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) PAN_4 PF14295.6 GAX26106.1 - 0.19 11.7 9.9 0.39 10.6 0.7 3.5 3 0 0 3 3 3 0 PAN domain ACI44 PF15270.6 GAX26106.1 - 2.9 8.2 8.8 1.4 9.1 0.2 2.9 3 0 0 3 3 3 0 Metallo-carboxypeptidase inhibitor Toxin_12 PF07740.12 GAX26106.1 - 9 7.1 21.1 0.18 12.5 2.5 3.6 3 0 0 3 3 3 0 Ion channel inhibitory toxin Ricin_B_lectin PF00652.22 GAX26107.1 - 1.3e-06 28.7 8.8 0.00012 22.3 0.8 2.8 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 GAX26107.1 - 0.016 14.8 0.9 0.033 13.8 0.9 1.6 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain WAP PF00095.21 GAX26107.1 - 0.031 14.7 1.2 0.031 14.7 1.2 3.1 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' PAN_4 PF14295.6 GAX26107.1 - 0.17 11.8 15.1 0.54 10.2 1.7 3.4 4 0 0 4 4 4 0 PAN domain CarbpepA_inh PF02977.15 GAX26107.1 - 0.39 10.6 13.5 2.1 8.2 2.5 2.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor CDtoxinA PF03498.14 GAX26108.1 - 0.0018 17.9 1.1 0.0059 16.2 0.6 1.9 1 1 0 2 2 2 1 Cytolethal distending toxin A/C domain Ricin_B_lectin PF00652.22 GAX26108.1 - 0.0035 17.6 1.8 0.012 15.8 0.3 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain WAP PF00095.21 GAX26108.1 - 2.7 8.4 8.0 0.17 12.3 1.5 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' MFS_1 PF07690.16 GAX26109.1 - 1.7e-17 63.4 17.8 1.5e-13 50.5 15.3 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily PsaL PF02605.15 GAX26109.1 - 0.024 14.3 2.1 0.048 13.3 0.1 2.4 2 1 1 3 3 3 0 Photosystem I reaction centre subunit XI DUF4234 PF14018.6 GAX26109.1 - 0.07 13.3 0.1 7.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF3487 PF11990.8 GAX26109.1 - 0.12 12.3 1.7 7.5 6.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) MgtC PF02308.16 GAX26109.1 - 10 6.5 13.5 3.5 8.0 6.1 3.8 2 2 1 3 3 3 0 MgtC family Gly_transf_sug PF04488.15 GAX26110.1 - 4.6e-10 40.0 0.0 1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 GAX26110.1 - 9.3e-06 25.2 0.0 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 GAX26110.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein ARL6IP6 PF15062.6 GAX26111.1 - 0.13 12.4 1.1 0.26 11.5 0.0 2.0 2 1 0 2 2 2 0 Haemopoietic lineage transmembrane helix Globin PF00042.22 GAX26112.1 - 9.6e-12 45.4 0.0 1.3e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Globin Globin PF00042.22 GAX26113.1 - 5.4e-12 46.2 0.0 8.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Globin DSPc PF00782.20 GAX26114.1 - 4.5e-06 26.5 0.1 6.7e-06 26.0 0.1 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 GAX26114.1 - 0.00022 21.0 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 GAX26114.1 - 0.02 14.4 0.3 0.035 13.7 0.3 1.5 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAX26114.1 - 0.055 13.4 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Sof1 PF04158.14 GAX26115.1 - 8.7e-26 90.0 10.4 2e-25 88.8 10.4 1.7 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 GAX26115.1 - 1.4e-21 76.4 12.7 2.6e-07 31.2 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX26115.1 - 3.2e-08 33.7 0.0 0.0071 16.6 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX26115.1 - 0.00024 20.2 0.1 0.3 10.0 0.0 2.5 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAX26115.1 - 0.00097 19.1 0.0 0.21 11.5 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAX26115.1 - 0.015 13.9 0.2 0.094 11.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Cellulase PF00150.18 GAX26116.1 - 1.4e-29 103.4 5.6 2.9e-29 102.4 5.6 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_6 PF03422.15 GAX26116.1 - 2.7e-29 102.0 0.9 3.1e-21 76.0 0.2 2.5 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX26116.1 - 7.5e-11 42.2 2.4 6e-06 26.4 0.3 2.5 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX26116.1 - 4e-09 36.8 0.4 0.0029 17.9 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) CopC PF04234.12 GAX26116.1 - 0.16 13.0 0.3 8.2 7.5 0.0 3.0 3 0 0 3 3 3 0 CopC domain Aminotran_1_2 PF00155.21 GAX26117.1 - 7.1e-51 173.5 0.0 8.9e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 GAX26117.1 - 6.6e-06 25.2 0.0 9.1e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.19 GAX26117.1 - 8.2e-05 21.7 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Glyco_tranf_2_4 PF13704.6 GAX26118.1 - 1.6e-07 31.7 0.8 5.8e-07 29.9 0.8 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX26118.1 - 0.038 13.6 1.4 0.42 10.2 1.4 2.3 1 1 0 1 1 1 0 Glycosyltransferase family 92 ThiF PF00899.21 GAX26119.1 - 2.2e-46 158.2 0.0 3.2e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 GAX26119.1 - 1.4e-28 100.4 0.2 2.2e-28 99.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus 2-Hacid_dh_C PF02826.19 GAX26119.1 - 0.002 17.5 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAX26119.1 - 0.0087 16.1 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF169 PF02596.15 GAX26119.1 - 0.096 12.6 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 DUF4406 PF14359.6 GAX26119.1 - 0.19 12.3 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) NPL4 PF05021.15 GAX26120.1 - 7.2e-28 97.8 0.7 5.3e-24 85.1 0.5 3.1 1 1 1 2 2 2 2 NPL4 family UN_NPL4 PF11543.8 GAX26120.1 - 0.00014 22.3 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 LtrA PF06772.11 GAX26121.1 - 1.9e-16 60.3 13.2 1.1e-15 57.8 13.2 1.9 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Colicin_V PF02674.16 GAX26121.1 - 0.012 15.6 1.8 0.038 14.0 0.4 2.4 1 1 1 2 2 2 0 Colicin V production protein EF-hand_7 PF13499.6 GAX26122.1 - 1.7e-07 31.6 0.3 3.8e-07 30.5 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX26122.1 - 1.5e-05 24.7 2.3 4.5e-05 23.2 0.6 2.7 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX26122.1 - 0.00012 21.7 0.2 0.95 9.6 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 GAX26122.1 - 0.0002 21.6 0.4 0.0016 18.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain PMI_typeI PF01238.21 GAX26122.1 - 0.0044 16.3 0.2 0.0054 16.0 0.2 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I EF-hand_1 PF00036.32 GAX26122.1 - 0.0049 16.3 1.1 0.043 13.4 0.1 2.7 3 0 0 3 3 3 1 EF hand TPR_1 PF00515.28 GAX26123.1 - 4.6e-32 108.5 4.8 4.9e-07 29.3 0.2 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26123.1 - 1.6e-29 99.6 6.4 1.2e-06 28.2 0.2 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAX26123.1 - 4.3e-21 75.3 9.2 7.4e-06 26.5 3.3 5.2 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 GAX26123.1 - 2.2e-19 68.5 13.3 0.00026 21.6 0.3 7.5 3 2 5 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAX26123.1 - 6.7e-18 63.3 4.3 0.00065 19.7 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX26123.1 - 9.7e-17 59.7 3.5 0.00013 21.7 0.1 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAX26123.1 - 2.4e-15 55.9 10.7 8.1e-05 22.2 0.3 6.3 4 2 2 6 6 6 4 TPR repeat TPR_17 PF13431.6 GAX26123.1 - 1.8e-13 49.8 13.4 0.016 15.5 0.1 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAX26123.1 - 3.9e-13 49.5 14.1 0.00021 21.5 2.7 5.0 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAX26123.1 - 4.2e-13 49.6 15.1 3.9e-06 27.3 0.7 4.8 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAX26123.1 - 4.6e-12 45.9 10.7 0.00073 19.6 0.3 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX26123.1 - 1.3e-07 31.8 8.8 1.4 9.7 0.1 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX26123.1 - 7.6e-05 22.5 11.4 0.74 9.8 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAX26123.1 - 0.00017 21.9 16.6 0.017 15.4 0.1 4.2 3 2 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX26123.1 - 0.00097 19.3 7.6 0.29 11.4 0.1 3.5 3 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 GAX26123.1 - 0.0059 17.1 6.9 0.026 14.9 0.1 3.7 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TFIIA PF03153.13 GAX26123.1 - 0.023 14.7 28.2 0.032 14.3 28.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIT PF04212.18 GAX26123.1 - 0.039 14.0 6.6 2 8.6 0.1 4.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 GAX26123.1 - 0.043 13.0 18.2 0.016 14.4 1.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX26123.1 - 0.068 13.8 1.5 29 5.7 0.1 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF4757 PF15949.5 GAX26123.1 - 0.077 13.5 10.9 0.18 12.3 10.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) DUF4248 PF14053.6 GAX26123.1 - 0.085 12.9 3.2 0.21 11.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) NSF PF02071.20 GAX26123.1 - 0.25 12.2 2.0 46 5.5 0.6 3.4 2 0 0 2 2 2 0 Aromatic-di-Alanine (AdAR) repeat ChAPs PF09295.10 GAX26123.1 - 0.67 8.9 10.4 1.8 7.5 0.1 3.2 3 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) FapA PF03961.13 GAX26123.1 - 2.5 6.6 5.5 3.8 6.0 5.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2000 PF09391.10 GAX26124.1 - 0.31 11.0 3.9 0.69 9.8 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2000) DUF1904 PF08921.11 GAX26124.1 - 0.41 11.0 4.8 0.22 11.9 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) Metallophos PF00149.28 GAX26125.1 - 1.7e-11 45.0 2.0 4.7e-10 40.3 2.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX26125.1 - 5.1e-06 26.8 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDC73_C PF05179.14 GAX26125.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal NYN_YacP PF05991.11 GAX26125.1 - 0.14 12.1 0.0 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 YacP-like NYN domain Alanine_zipper PF11839.8 GAX26126.1 - 0.0021 18.4 25.6 0.14 12.5 7.0 4.8 2 1 1 3 3 3 3 Alanine-zipper, major outer membrane lipoprotein Y_phosphatase3 PF13350.6 GAX26127.1 - 1.4e-05 25.2 0.0 1.6e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Pet20 PF08692.10 GAX26127.1 - 0.18 12.5 0.0 0.29 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet20 DHO_dh PF01180.21 GAX26128.1 - 1.7e-100 336.0 0.0 2.2e-100 335.7 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 GAX26128.1 - 1.7e-05 24.0 0.0 6.7e-05 22.1 0.0 1.9 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 GAX26128.1 - 0.00048 19.6 0.0 0.00079 18.9 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase HHV-5_US34A PF17087.5 GAX26130.1 - 0.21 11.7 0.3 0.41 10.8 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus US34A protein family MgtE PF01769.16 GAX26130.1 - 0.66 10.4 6.7 0.57 10.6 1.3 2.3 2 1 0 2 2 2 0 Divalent cation transporter CCDC-167 PF15188.6 GAX26131.1 - 0.21 12.0 1.6 0.39 11.1 1.5 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Lipid_DES PF08557.10 GAX26131.1 - 2.2 7.8 3.8 0.44 10.1 0.2 1.5 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) UPF0047 PF01894.17 GAX26132.1 - 1.1e-38 132.0 0.2 1.9e-38 131.1 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0047 Ysc84 PF04366.12 GAX26134.1 - 2.6e-26 91.9 0.2 4.4e-26 91.1 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator PX PF00787.24 GAX26134.1 - 1e-08 35.1 0.1 1.9e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 PX domain SH3BGR PF04908.15 GAX26135.1 - 1.7e-08 34.5 2.0 0.01 16.0 0.0 4.3 3 1 1 4 4 4 3 SH3-binding, glutamic acid-rich protein zf-MYND PF01753.18 GAX26135.1 - 2.1e-05 24.5 16.1 4.1e-05 23.6 16.1 1.5 1 0 0 1 1 1 1 MYND finger RF-1 PF00472.20 GAX26135.1 - 4.4 7.3 7.7 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 RF-1 domain Sugar_tr PF00083.24 GAX26136.1 - 2e-94 317.0 23.5 4.5e-94 315.9 23.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAX26136.1 - 3.7e-17 62.3 33.4 3.7e-17 62.3 33.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFAP1 PF06991.11 GAX26137.1 - 7.6e-45 153.4 24.9 7.6e-45 153.4 24.9 2.6 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing FG-GAP_2 PF14312.6 GAX26138.1 - 7.9e-13 48.4 21.7 2.4e-06 27.7 0.1 6.3 6 0 0 6 6 6 3 FG-GAP repeat FG-GAP PF01839.23 GAX26138.1 - 0.16 12.2 1.2 1.6 8.9 0.0 3.4 3 0 0 3 3 3 0 FG-GAP repeat HisK_sensor PF18698.1 GAX26138.1 - 0.16 12.4 0.6 3.1 8.2 0.0 3.0 3 0 0 3 3 3 0 Histidine kinase sensor domain MatE PF01554.18 GAX26139.1 - 3.4e-31 108.1 23.8 2e-16 60.1 4.6 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAX26139.1 - 0.00068 19.7 0.7 0.00068 19.7 0.7 4.8 4 2 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain DUF3612 PF12268.8 GAX26139.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Phage_holin_2_2 PF10746.9 GAX26139.1 - 0.44 10.2 3.6 1.8 8.3 3.6 2.2 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II LTD PF00932.19 GAX26140.1 - 1.4e-07 31.8 0.8 3.6e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 Lamin Tail Domain CSRNP_N PF16019.5 GAX26141.1 - 0.064 13.2 1.0 0.18 11.7 0.9 1.9 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus HflK_N PF12221.8 GAX26142.1 - 0.046 13.7 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal LNS2 PF08235.13 GAX26142.1 - 0.12 11.8 0.0 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Ribosomal_L17 PF01196.19 GAX26144.1 - 1.7e-32 112.2 1.7 2.2e-32 111.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 LRR_8 PF13855.6 GAX26146.1 - 4.9e-30 103.1 40.3 8.6e-07 28.6 0.6 8.8 4 4 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 GAX26146.1 - 1.1e-25 89.2 42.0 0.00093 19.5 0.3 11.2 4 2 11 15 15 15 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX26146.1 - 2.1e-13 48.8 24.0 0.47 11.2 0.0 13.9 14 1 0 14 14 14 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX26146.1 - 0.012 15.6 30.4 11 6.4 0.1 10.5 12 0 0 12 12 12 0 Leucine Rich repeat EMP70 PF02990.16 GAX26147.1 - 7.7e-173 575.9 1.5 9.9e-173 575.5 1.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ApoL PF05461.11 GAX26148.1 - 0.00086 18.7 3.7 0.011 15.0 3.7 2.4 1 1 0 1 1 1 1 Apolipoprotein L DUF4781 PF16013.5 GAX26148.1 - 0.011 14.6 0.4 0.019 13.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Methyltransf_32 PF13679.6 GAX26149.1 - 5.6e-32 110.9 0.0 1.9e-31 109.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX26149.1 - 2.7e-06 27.2 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 GAX26149.1 - 0.00023 20.8 0.8 0.048 13.2 0.6 3.1 1 1 0 2 2 2 1 Methyltransferase TRM13 Methyltransf_25 PF13649.6 GAX26149.1 - 0.0024 18.6 0.0 0.0086 16.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain NigD_C PF17415.2 GAX26149.1 - 0.09 12.9 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 NigD-like C-terminal beta sandwich domain Mucin PF01456.17 GAX26149.1 - 3.6 7.6 10.2 3.6 7.6 1.5 3.0 2 1 0 2 2 2 0 Mucin-like glycoprotein Rep_fac-A_3 PF08661.11 GAX26150.1 - 1.7e-14 54.1 0.0 1.8e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 MTS PF05175.14 GAX26151.1 - 7.4e-11 41.9 0.1 2.3e-07 30.5 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 GAX26151.1 - 9.1e-10 38.4 0.2 1.4e-09 37.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAX26151.1 - 2e-07 31.6 0.1 6.1e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX26151.1 - 4.2e-07 29.9 0.0 7.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GAX26151.1 - 3.5e-06 26.8 1.2 0.078 12.7 1.1 2.7 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 GAX26151.1 - 8e-05 23.2 0.1 0.00029 21.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX26151.1 - 8.9e-05 22.2 0.0 0.016 14.8 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 GAX26151.1 - 0.00076 19.1 0.0 0.0013 18.4 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 GAX26151.1 - 0.0018 18.1 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 GAX26151.1 - 0.0064 17.2 0.1 0.033 14.9 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAX26151.1 - 0.0096 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAX26151.1 - 0.031 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 GAX26151.1 - 0.032 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 GAX26151.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 GAX26151.1 - 0.064 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAX26151.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 7tm_1 PF00001.21 GAX26154.1 - 2.1 7.6 23.7 3.4 6.9 23.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF5457 PF17540.2 GAX26155.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5457) CENP-B_N PF04218.13 GAX26156.1 - 2.9e-11 42.8 6.5 4e-07 29.6 0.3 2.5 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 GAX26156.1 - 1.1e-10 41.6 1.6 1.3e-05 25.5 0.1 2.8 2 0 0 2 2 2 2 Transposase HTH_23 PF13384.6 GAX26156.1 - 6.8e-08 32.1 0.1 0.0081 15.9 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 GAX26156.1 - 2.9e-05 24.1 0.0 0.0043 17.2 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 GAX26156.1 - 0.00014 21.2 0.0 0.0043 16.4 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1_2 PF13022.6 GAX26156.1 - 0.00085 19.5 8.4 0.0075 16.4 0.2 3.1 2 1 1 3 3 3 2 Helix-turn-helix of insertion element transposase Phage_CI_repr PF07022.13 GAX26156.1 - 0.001 19.1 0.2 1.2 9.2 0.0 2.6 2 0 0 2 2 2 2 Bacteriophage CI repressor helix-turn-helix domain HTH_17 PF12728.7 GAX26156.1 - 0.0013 18.9 0.1 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_10 PF04967.12 GAX26156.1 - 0.0061 16.3 0.1 0.37 10.6 0.0 2.8 2 0 0 2 2 2 1 HTH DNA binding domain Phage_Nu1 PF07471.12 GAX26156.1 - 0.011 15.6 0.3 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 MerR_1 PF13411.6 GAX26156.1 - 0.011 15.8 0.2 0.3 11.2 0.0 2.6 1 1 1 2 2 2 0 MerR HTH family regulatory protein HTH_30 PF13556.6 GAX26156.1 - 0.017 14.9 0.7 2.9 7.8 0.0 3.3 3 1 0 3 3 3 0 PucR C-terminal helix-turn-helix domain ANT PF03374.14 GAX26156.1 - 0.029 14.7 0.2 0.029 14.7 0.2 3.2 2 1 1 3 3 2 0 Phage antirepressor protein KilAC domain HTH_29 PF13551.6 GAX26156.1 - 0.051 13.6 0.0 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn helix DUF1153 PF06627.11 GAX26156.1 - 0.076 13.2 0.2 5.9 7.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1153) Terminase_5 PF06056.12 GAX26156.1 - 0.12 12.2 0.2 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF1323 PF07037.11 GAX26156.1 - 2.9 8.3 15.2 0.55 10.6 0.2 3.4 3 0 0 3 3 2 0 Putative transcription regulator (DUF1323) GIDA_assoc PF13932.6 GAX26156.1 - 5.6 7.1 14.8 1.3 9.1 2.2 2.5 2 1 0 2 2 2 0 GidA associated domain TLD PF07534.16 GAX26157.1 - 5.2e-29 101.2 1.1 1.2e-28 100.1 0.0 2.2 3 0 0 3 3 3 1 TLD ATP-grasp_3 PF02655.14 GAX26157.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain RRM_1 PF00076.22 GAX26158.1 - 2.2e-09 37.0 0.1 4.2e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 GAX26158.1 - 7.6e-09 35.3 12.8 1.1e-05 25.2 2.9 2.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SelP_N PF04592.14 GAX26158.1 - 0.027 13.9 8.4 0.18 11.2 6.7 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region zf_CCCH_4 PF18345.1 GAX26158.1 - 0.27 11.3 10.4 0.26 11.4 1.4 2.5 2 0 0 2 2 2 0 Zinc finger domain Ferlin_C PF16165.5 GAX26158.1 - 2.4 8.1 3.9 3.9 7.4 3.9 1.3 1 0 0 1 1 1 0 Ferlin C-terminus CDC45 PF02724.14 GAX26158.1 - 2.9 6.1 8.3 3.4 5.8 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Torus PF16131.5 GAX26158.1 - 3.4 8.4 14.4 0.78 10.5 0.6 3.3 3 1 1 4 4 4 0 Torus domain DUF755 PF05501.11 GAX26158.1 - 6.8 7.0 18.2 12 6.2 18.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RNA_polI_A34 PF08208.11 GAX26158.1 - 7.1 6.7 14.4 19 5.3 9.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 ZZ PF00569.17 GAX26159.1 - 1.1e-07 31.5 1.1 2.7e-07 30.3 1.1 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 GAX26159.1 - 0.0032 17.3 0.0 0.008 16.1 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Glyco_trans_2_3 PF13632.6 GAX26161.1 - 5.1e-23 82.0 0.1 1.2e-22 80.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX26161.1 - 3.9e-15 56.4 0.0 6.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX26161.1 - 4.9e-13 49.2 0.1 7.6e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX26161.1 - 1.3e-07 31.2 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Dicty_CAR PF05462.11 GAX26161.1 - 0.16 11.0 4.5 0.048 12.8 1.0 1.7 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor Glyco_trans_2_3 PF13632.6 GAX26162.1 - 4.9e-23 82.1 0.6 1.4e-22 80.6 0.6 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAX26162.1 - 1.6e-17 64.2 0.0 2.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX26162.1 - 2.7e-13 50.1 0.0 5.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAX26162.1 - 2.4e-09 36.9 0.0 5.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 GAX26162.1 - 0.0055 15.3 0.1 0.021 13.3 0.0 1.9 2 0 0 2 2 2 1 Cellulose synthase Sulfotransfer_3 PF13469.6 GAX26162.1 - 0.053 13.9 0.0 0.19 12.1 0.0 2.0 1 1 0 1 1 1 0 Sulfotransferase family Sec23_helical PF04815.15 GAX26163.1 - 0.00015 21.5 0.4 0.0007 19.4 0.3 2.3 2 1 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_trunk PF04811.15 GAX26163.1 - 0.0059 16.2 0.2 2.6 7.5 0.2 3.4 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zinc_ribbon_2 PF13240.6 GAX26163.1 - 0.87 9.4 3.2 3.5 7.5 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain tRNA-synt_1 PF00133.22 GAX26164.1 - 2.2e-213 709.9 0.1 3.2e-213 709.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAX26164.1 - 2.7e-24 85.9 0.0 6.3e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAX26164.1 - 6.1e-14 51.6 1.9 0.00068 18.5 0.3 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAX26164.1 - 0.0075 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ion_trans_2 PF07885.16 GAX26165.1 - 3.1e-16 59.1 12.4 5.6e-15 55.1 3.9 2.2 2 0 0 2 2 2 2 Ion channel EF-hand_1 PF00036.32 GAX26165.1 - 1.9e-08 33.3 3.6 0.0012 18.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAX26165.1 - 3.2e-08 33.9 2.5 0.0014 19.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX26165.1 - 1.8e-07 30.5 1.9 0.012 15.5 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX26165.1 - 2.8e-06 26.5 2.7 0.046 13.2 0.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAX26165.1 - 3.8e-05 23.5 3.5 0.032 14.1 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair DUF4456 PF14644.6 GAX26165.1 - 0.0012 18.6 0.1 1.2 8.8 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4456) Ion_trans PF00520.31 GAX26165.1 - 0.0013 18.0 4.3 0.0098 15.1 4.3 2.2 1 1 0 1 1 1 1 Ion transport protein SPARC_Ca_bdg PF10591.9 GAX26165.1 - 0.015 15.6 0.7 0.35 11.2 0.1 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GAX26165.1 - 0.017 15.3 0.2 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain Vault_4 PF17796.1 GAX26165.1 - 0.049 13.7 0.4 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Major Vault Protein repeat domain Excalibur PF05901.11 GAX26165.1 - 3.9 8.2 4.5 15 6.3 0.4 2.8 3 0 0 3 3 3 0 Excalibur calcium-binding domain MORN PF02493.20 GAX26167.1 - 9.1e-30 100.8 36.6 1.6e-05 24.5 1.4 7.2 7 0 0 7 7 7 7 MORN repeat DUF4649 PF15507.6 GAX26167.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) Hydrolase_4 PF12146.8 GAX26168.1 - 6e-08 32.3 0.1 5.8e-05 22.5 0.1 2.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GAX26168.1 - 1.1e-06 28.7 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAX26168.1 - 0.0001 21.4 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GAX26168.1 - 0.00025 20.6 0.0 0.00046 19.7 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAX26168.1 - 0.00036 21.2 0.2 0.00047 20.8 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAX26168.1 - 0.0074 16.1 0.2 0.83 9.4 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 GAX26168.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein LIDHydrolase PF10230.9 GAX26168.1 - 0.073 12.6 0.1 0.1 12.1 0.1 1.3 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase PARP_regulatory PF01358.18 GAX26168.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit Abhydrolase_1 PF00561.20 GAX26168.1 - 1.5 8.4 4.1 2.9 7.5 0.0 2.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold tRNA-synt_1g PF09334.11 GAX26169.1 - 4.1e-94 315.5 0.4 2.8e-91 306.2 0.4 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAX26169.1 - 5e-30 104.3 0.7 1.4e-19 69.9 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 GAX26169.1 - 2.4e-24 85.2 0.1 5e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 GAX26169.1 - 4.9e-12 45.8 0.7 7.2e-06 25.5 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GAX26169.1 - 7.8e-06 25.0 0.1 0.00018 20.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (K) AP3D1 PF06375.11 GAX26169.1 - 0.88 9.8 5.8 1.2 9.4 3.1 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 SMC_N PF02463.19 GAX26170.1 - 0.00011 21.8 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX26170.1 - 0.00012 22.0 0.1 0.24 11.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 GAX26170.1 - 0.00019 21.6 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX26170.1 - 0.00086 19.8 0.0 0.45 11.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 GAX26170.1 - 0.0064 16.8 0.0 0.017 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAX26170.1 - 0.032 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 GAX26170.1 - 0.033 13.8 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 GAX26170.1 - 0.051 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.6 GAX26170.1 - 0.07 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 GAX26170.1 - 0.078 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 GAX26170.1 - 0.13 12.1 0.1 0.38 10.5 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GAX26170.1 - 0.14 11.4 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin TPR_14 PF13428.6 GAX26172.1 - 1.9e-16 59.4 28.1 2.1e-05 24.9 0.1 9.7 5 3 5 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26172.1 - 3.8e-16 57.8 33.3 0.00016 21.5 0.2 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAX26172.1 - 3.2e-15 56.4 15.0 0.0011 19.4 0.2 6.4 3 2 5 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX26172.1 - 1.7e-12 46.5 6.1 0.0019 18.2 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAX26172.1 - 1.3e-10 41.3 20.1 0.046 13.9 1.5 6.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAX26172.1 - 1.3e-10 41.4 27.1 5.4e-05 23.4 1.3 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX26172.1 - 3.1e-09 36.4 11.4 0.037 13.7 0.1 6.7 5 1 2 7 7 7 3 TPR repeat TPR_17 PF13431.6 GAX26172.1 - 4.6e-09 36.0 17.2 0.069 13.5 0.1 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX26172.1 - 2.5e-07 30.2 21.2 0.0061 16.3 0.2 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX26172.1 - 0.00016 22.1 16.0 1.1 10.0 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX26172.1 - 0.0003 20.6 7.1 4.6 7.5 0.1 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX26172.1 - 0.003 18.2 20.1 0.11 13.2 0.1 5.5 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAX26172.1 - 0.04 13.8 17.5 3.3 7.7 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PknG_TPR PF16918.5 GAX26172.1 - 0.25 10.0 9.7 0.45 9.2 1.3 3.1 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat CBFB_NFYA PF02045.15 GAX26174.1 - 5.2e-23 81.4 8.1 9.9e-23 80.5 8.1 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ETF_alpha PF00766.19 GAX26175.1 - 7.6e-36 122.0 3.4 1.4e-35 121.1 2.3 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 GAX26175.1 - 3.6e-21 75.9 1.9 6e-21 75.1 1.9 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L35p PF01632.19 GAX26176.1 - 5.5e-12 46.0 4.8 6.8e-12 45.7 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 cNMP_binding PF00027.29 GAX26177.1 - 9.2e-12 44.9 0.0 1.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Root_cap PF06830.11 GAX26177.1 - 0.0062 16.6 0.0 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 Root cap Rrp40_N PF18311.1 GAX26177.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain ACBP PF00887.19 GAX26181.1 - 1.1e-14 54.4 0.2 1.7e-14 53.8 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Kinesin PF00225.23 GAX26185.1 - 1.9e-100 336.0 0.1 4.3e-100 334.9 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX26185.1 - 1e-51 174.8 0.2 3.8e-51 173.0 0.0 2.1 2 1 1 3 3 3 1 Microtubule binding Jnk-SapK_ap_N PF09744.9 GAX26185.1 - 0.00076 19.7 11.6 0.00076 19.7 11.6 4.7 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 Bac_DnaA PF00308.18 GAX26185.1 - 0.013 15.4 0.3 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein DUF2335 PF10097.9 GAX26185.1 - 0.17 11.8 2.3 1.6 8.7 2.3 2.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Shugoshin_N PF07558.11 GAX26185.1 - 0.21 11.5 5.3 8.8 6.3 0.5 3.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region V-SNARE PF05008.15 GAX26185.1 - 0.29 11.5 16.1 1.8 9.0 0.3 4.8 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus AAA_16 PF13191.6 GAX26185.1 - 0.61 10.5 0.0 0.61 10.5 0.0 4.0 2 2 0 2 2 2 0 AAA ATPase domain HSBP1 PF06825.12 GAX26185.1 - 3.2 7.7 9.1 1.3 8.9 0.5 3.5 3 0 0 3 3 3 0 Heat shock factor binding protein 1 LapA_dom PF06305.11 GAX26185.1 - 9.3 6.2 7.0 69 3.4 0.3 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pro_isomerase PF00160.21 GAX26186.1 - 1.4e-08 35.1 0.0 2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spore_YhaL PF14147.6 GAX26186.1 - 3.7 7.3 4.2 7 6.4 4.2 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL UAA PF08449.11 GAX26187.1 - 3.1e-49 167.8 16.7 3.8e-49 167.5 16.7 1.0 1 0 0 1 1 1 1 UAA transporter family TMEM252 PF15664.5 GAX26187.1 - 0.13 12.0 1.2 6.9 6.4 0.1 2.5 2 1 0 2 2 2 0 Transmembrane protein 252 family Phage_holin_3_6 PF07332.11 GAX26187.1 - 2.2 8.3 7.3 3.9 7.6 0.3 3.7 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2157 PF09925.9 GAX26187.1 - 7.3 6.4 11.3 7.7 6.3 6.6 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Arf PF00025.21 GAX26188.1 - 9.4e-43 145.7 0.0 1.3e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAX26188.1 - 9.3e-12 44.7 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAX26188.1 - 2.7e-09 36.8 0.0 3.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX26188.1 - 3.3e-09 37.0 0.0 8.4e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAX26188.1 - 1.6e-07 30.9 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAX26188.1 - 1.6e-06 28.2 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAX26188.1 - 4.4e-06 26.1 1.9 0.0034 16.6 0.0 3.4 1 1 1 3 3 3 2 G-protein alpha subunit GTP_EFTU PF00009.27 GAX26188.1 - 7.5e-05 22.4 0.1 0.0058 16.2 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAX26188.1 - 0.001 18.6 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX26188.1 - 0.0023 17.9 0.2 0.69 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAX26188.1 - 0.019 15.2 0.3 0.41 10.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX26188.1 - 0.066 13.1 0.1 9.4 6.1 0.0 2.7 3 0 0 3 3 3 0 NACHT domain cobW PF02492.19 GAX26188.1 - 0.068 12.8 0.2 3.3 7.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAX26188.1 - 0.19 12.1 4.7 2 8.8 0.3 2.4 1 1 1 2 2 2 0 AAA ATPase domain DLIC PF05783.11 GAX26188.1 - 0.19 10.5 0.2 0.34 9.7 0.2 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) HEAT PF02985.22 GAX26189.1 - 8.3e-13 47.4 16.6 5.8e-05 23.0 0.0 9.1 10 0 0 10 10 8 3 HEAT repeat Vac14_Fab1_bd PF12755.7 GAX26189.1 - 2e-11 44.4 1.9 0.038 14.6 0.1 5.9 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 GAX26189.1 - 1.4e-10 41.4 3.2 0.056 13.8 0.0 7.8 6 2 3 9 9 9 3 HEAT repeats MMS19_C PF12460.8 GAX26189.1 - 1.2e-09 37.8 13.6 2.5e-05 23.6 0.0 4.0 2 1 2 4 4 4 3 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 GAX26189.1 - 1.8e-09 37.9 13.9 9.9e-06 25.9 0.0 8.9 11 1 1 12 12 11 1 HEAT-like repeat IBN_N PF03810.19 GAX26189.1 - 2.6e-08 33.7 3.4 1.9e-07 30.9 0.5 3.6 3 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 GAX26189.1 - 8.4e-08 32.1 3.7 0.011 15.4 0.0 4.6 3 2 1 4 4 4 2 CLASP N terminal IFRD PF05004.13 GAX26189.1 - 4e-05 22.9 13.2 0.031 13.4 0.1 5.1 2 2 4 6 6 6 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 GAX26189.1 - 0.00024 21.2 0.9 0.00024 21.2 0.9 3.3 4 2 0 4 4 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAX26189.1 - 0.0033 17.4 0.1 1.3 9.1 0.0 4.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 GAX26189.1 - 0.019 14.9 8.9 3.9 7.4 0.0 5.6 4 2 3 7 7 7 0 Domain of unknown function (DUF3385) PD-C2-AF1 PF09310.10 GAX26189.1 - 0.046 13.1 2.0 0.28 10.6 0.2 2.4 2 0 0 2 2 2 0 POU domain, class 2, associating factor 1 TIP120 PF08623.10 GAX26189.1 - 0.15 11.8 0.6 5.4 6.8 0.0 2.9 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Urb2 PF10441.9 GAX26189.1 - 2.5 8.0 6.9 1.7 8.5 3.8 2.5 2 1 0 2 2 2 0 Urb2/Npa2 family ETF_QO PF05187.13 GAX26190.1 - 6.8e-38 129.0 0.1 1.1e-37 128.3 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 GAX26190.1 - 1.5e-11 44.0 0.0 3.9e-06 26.2 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX26190.1 - 9.4e-08 32.0 0.8 0.0026 17.4 0.9 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX26190.1 - 6.6e-06 26.3 0.1 3e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAX26190.1 - 3.5e-05 22.7 0.3 5.9e-05 21.9 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAX26190.1 - 0.00011 21.6 0.0 0.00023 20.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX26190.1 - 0.00012 21.5 0.2 0.0002 20.7 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX26190.1 - 0.0016 17.8 0.1 0.0028 17.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAX26190.1 - 0.0017 17.7 0.1 0.012 14.9 0.2 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAX26190.1 - 0.0049 16.0 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAX26190.1 - 0.0067 16.4 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAX26190.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX26190.1 - 0.019 15.5 0.1 3.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX26190.1 - 0.11 11.4 0.2 0.24 10.2 0.2 1.6 1 0 0 1 1 1 0 Tryptophan halogenase DER1 PF04511.15 GAX26191.1 - 2.9e-58 197.0 13.9 3.6e-58 196.7 13.9 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 GAX26191.1 - 0.094 12.5 0.6 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Oleosin QueT PF06177.11 GAX26191.1 - 0.82 10.0 7.1 0.11 12.9 2.9 1.6 2 0 0 2 2 2 0 QueT transporter Ald_Xan_dh_C2 PF02738.18 GAX26192.1 - 4.4e-176 586.6 0.1 6.9e-176 585.9 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 GAX26192.1 - 2.9e-36 124.8 0.0 5.6e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 GAX26192.1 - 2.6e-27 95.0 0.6 6.9e-27 93.6 0.2 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 GAX26192.1 - 1.7e-15 57.3 0.0 3.6e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 GAX26192.1 - 5.9e-07 29.4 0.0 1.6e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain adh_short PF00106.25 GAX26193.1 - 5.7e-35 120.5 0.0 7.2e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX26193.1 - 3.1e-22 79.3 0.0 4.2e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX26193.1 - 7.3e-07 29.3 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX26193.1 - 7.7e-06 25.2 0.1 1.1e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 GAX26193.1 - 0.00029 20.3 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Pyr_redox_2 PF07992.14 GAX26193.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CbiA PF01656.23 GAX26193.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 3HCDH_N PF02737.18 GAX26193.1 - 0.034 14.0 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peripla_BP_6 PF13458.6 GAX26193.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Periplasmic binding protein Epimerase PF01370.21 GAX26193.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family zf-MYND PF01753.18 GAX26194.1 - 2.1e-05 24.5 10.7 3.9e-05 23.6 10.7 1.5 1 0 0 1 1 1 1 MYND finger DUF1251 PF06856.11 GAX26194.1 - 0.011 15.4 0.0 0.37 10.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1251) PPC PF04151.15 GAX26194.1 - 0.022 15.8 0.1 31 5.7 0.0 3.6 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain PepSY_2 PF13670.6 GAX26194.1 - 0.044 13.8 0.0 19 5.4 0.0 4.3 4 1 1 5 5 5 0 Peptidase propeptide and YPEB domain IF3_N PF05198.16 GAX26194.1 - 0.16 12.2 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain zf-Mss51 PF13824.6 GAX26194.1 - 1.2 9.3 8.2 4.4 7.5 8.2 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 GAX26194.1 - 7.2 7.0 10.0 16 5.9 10.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding QRPTase_C PF01729.19 GAX26195.1 - 8.9e-55 185.0 0.3 1.2e-54 184.7 0.3 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 GAX26195.1 - 1.7e-14 53.6 0.0 4.7e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain LysR_substrate PF03466.20 GAX26195.1 - 0.016 14.6 0.9 0.2 11.0 0.1 2.7 2 1 1 3 3 3 0 LysR substrate binding domain Voltage_CLC PF00654.20 GAX26196.1 - 1.4e-26 93.6 33.4 2.8e-20 72.9 8.8 3.3 2 1 0 3 3 3 2 Voltage gated chloride channel Cas_Csy4 PF09618.10 GAX26196.1 - 2.9 8.0 4.8 1.7 8.7 0.4 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) YqzE PF14038.6 GAX26196.1 - 6.6 6.8 9.0 6.8 6.8 0.5 2.8 2 0 0 2 2 2 0 YqzE-like protein Sulfotransfer_3 PF13469.6 GAX26197.1 - 2e-06 28.3 0.3 0.00044 20.7 0.0 3.3 3 0 0 3 3 3 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 GAX26197.1 - 0.0013 18.3 0.6 0.075 12.5 0.7 2.7 2 1 0 2 2 2 1 Sulfotransferase domain RelB PF04221.12 GAX26197.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 RelB antitoxin CBM_6 PF03422.15 GAX26198.1 - 9.1e-25 87.4 1.0 2.5e-11 44.0 0.2 2.2 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX26198.1 - 1.4e-11 44.5 0.6 9.6e-07 28.9 0.1 2.4 2 0 0 2 2 2 2 DUF5010 C-terminal domain Cellulase PF00150.18 GAX26200.1 - 1.5e-20 73.8 2.1 3.2e-20 72.7 2.1 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_6 PF03422.15 GAX26200.1 - 1.3e-13 51.3 0.2 8.3e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX26200.1 - 2.3e-06 27.7 0.1 0.014 15.5 0.0 2.6 2 0 0 2 2 2 2 DUF5010 C-terminal domain VD10_N PF08476.10 GAX26200.1 - 0.014 15.0 0.1 0.05 13.3 0.1 1.9 1 0 0 1 1 1 0 Viral D10 N-terminal DUF4384 PF14326.6 GAX26200.1 - 0.035 14.2 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) CBM_6 PF03422.15 GAX26201.1 - 2.5e-28 98.9 0.4 4.6e-13 49.6 0.5 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX26201.1 - 5e-15 55.7 6.0 1.1e-14 54.6 6.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX26201.1 - 1.4e-07 31.6 0.2 0.00067 19.8 0.1 2.7 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX26201.1 - 0.0011 19.3 0.2 0.43 10.8 0.3 2.5 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) DUF3385 PF11865.8 GAX26201.1 - 0.0027 17.6 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) Caud_tail_N PF16838.5 GAX26201.1 - 0.12 12.9 0.3 3.9 7.9 0.0 2.7 3 0 0 3 3 3 0 Caudoviral major tail protein N-terminus CBM_6 PF03422.15 GAX26202.1 - 2.2e-35 121.7 0.9 2e-18 66.9 0.4 2.2 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX26202.1 - 4.4e-11 42.9 0.0 0.0001 22.4 0.0 2.6 2 1 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX26202.1 - 1.6e-06 28.4 0.3 0.0093 16.2 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) OB_NTP_bind PF07717.16 GAX26203.1 - 1e-14 54.6 0.0 2.8e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX26203.1 - 1.7e-14 54.1 0.0 4.9e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 GAX26203.1 - 7.2e-13 48.8 1.1 4e-12 46.4 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 GAX26203.1 - 2.3e-07 30.8 0.3 1.9e-06 27.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase T2SSE PF00437.20 GAX26203.1 - 0.0022 17.1 0.5 0.0041 16.2 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein DND1_DSRM PF14709.7 GAX26203.1 - 0.0035 17.5 0.2 0.0085 16.3 0.2 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_19 PF13245.6 GAX26203.1 - 0.004 17.5 2.5 0.1 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX26203.1 - 0.0056 16.9 0.3 0.026 14.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX26203.1 - 0.023 15.1 0.1 0.023 15.1 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 GAX26203.1 - 0.03 14.5 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 GAX26203.1 - 0.03 14.0 0.1 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX26203.1 - 0.036 13.6 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 GAX26203.1 - 0.037 13.4 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 GAX26203.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 GAX26203.1 - 0.1 12.5 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain APC1_C PF18122.1 GAX26203.1 - 0.14 12.1 1.0 0.34 10.8 0.4 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain ABC_tran PF00005.27 GAX26203.1 - 0.16 12.5 0.0 0.16 12.5 0.0 2.5 2 1 0 2 2 1 0 ABC transporter PG_binding_2 PF08823.11 GAX26203.1 - 0.3 11.4 2.0 2.3 8.6 0.2 2.8 3 0 0 3 3 2 0 Putative peptidoglycan binding domain AAA_23 PF13476.6 GAX26203.1 - 0.31 11.5 2.2 4.5 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain RVT_2 PF07727.14 GAX26204.1 - 2.2e-12 47.1 0.0 3.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSF_DNA-bind PF00447.17 GAX26205.1 - 3e-20 72.6 0.0 5.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding OmpH PF03938.14 GAX26206.1 - 0.12 12.7 5.3 0.95 9.8 0.0 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) ELFV_dehydrog PF00208.21 GAX26207.1 - 5e-37 127.9 0.0 8e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAX26207.1 - 1.9e-19 68.8 1.2 3.7e-13 48.0 0.0 3.8 4 0 0 4 4 4 3 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 GAX26207.1 - 0.017 15.0 0.0 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FTCD PF02971.14 GAX26207.1 - 0.23 11.5 0.7 3.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Formiminotransferase domain Methyltransf_11 PF08241.12 GAX26208.1 - 2.3e-19 69.8 0.1 7.3e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX26208.1 - 1.8e-16 60.6 0.2 7.3e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX26208.1 - 3.7e-14 52.8 0.2 6.4e-14 52.0 0.2 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX26208.1 - 2.9e-10 39.9 0.0 6.4e-10 38.8 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAX26208.1 - 4.9e-08 33.0 0.0 8.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAX26208.1 - 6.9e-07 30.2 0.1 2.3e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GAX26208.1 - 1.3e-05 24.7 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 GAX26208.1 - 9.1e-05 23.1 0.0 0.00023 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAX26208.1 - 0.00011 22.1 0.0 0.00039 20.2 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 GAX26208.1 - 0.00037 19.7 0.0 0.00062 19.0 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase FtsJ PF01728.19 GAX26208.1 - 0.00072 19.7 0.5 0.0014 18.8 0.3 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 GAX26208.1 - 0.00087 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 GAX26208.1 - 0.00091 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 GAX26208.1 - 0.00098 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 GAX26208.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 GAX26208.1 - 0.0043 16.8 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 GAX26208.1 - 0.0078 16.0 0.3 0.015 15.1 0.2 1.5 1 1 0 1 1 1 1 Met-10+ like-protein Oxidored_FMN PF00724.20 GAX26208.1 - 0.019 14.3 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family GidB PF02527.15 GAX26208.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G AAA_31 PF13614.6 GAX26208.1 - 0.061 13.2 0.1 0.14 12.1 0.0 1.5 1 1 1 2 2 2 0 AAA domain SBP_bac_5 PF00496.22 GAX26208.1 - 0.19 10.6 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle TraI_2_C PF07515.11 GAX26209.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term DUF285 PF03382.14 GAX26210.1 - 4.4e-92 304.1 37.9 2.8e-34 117.5 10.4 3.0 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 LEF-4 PF05098.12 GAX26210.1 - 0.00066 18.6 0.2 0.0029 16.5 0.1 1.8 1 1 1 2 2 2 1 Late expression factor 4 (LEF-4) Terpene_synth_C PF03936.16 GAX26210.1 - 0.058 12.7 0.3 18 4.6 0.0 3.6 4 1 1 5 5 5 0 Terpene synthase family, metal binding domain U5_2-snRNA_bdg PF10597.9 GAX26210.1 - 1.4 9.0 4.2 9.8 6.3 0.1 3.2 1 1 3 4 4 4 0 U5-snRNA binding site 2 of PrP8 DUF1800 PF08811.11 GAX26211.1 - 4.3e-43 147.9 0.0 1.2e-22 80.5 0.0 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 GAX26211.1 - 3e-31 108.9 3.9 4.7e-31 108.2 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Cyt-b5 PF00173.28 GAX26211.1 - 0.016 15.3 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF2639 PF11121.8 GAX26211.1 - 0.32 11.1 1.0 0.78 9.8 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) Methyltransf_21 PF05050.12 GAX26212.1 - 0.00017 21.7 0.1 0.00038 20.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF1611_N PF17396.2 GAX26212.1 - 0.07 13.4 0.0 0.82 9.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DUF4824 PF16106.5 GAX26212.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) GCK PF07802.11 GAX26212.1 - 0.74 10.3 3.3 0.45 11.0 0.5 2.1 2 0 0 2 2 2 0 GCK domain PEPcase PF00311.17 GAX26213.1 - 3.2e-246 819.3 0.0 6.3e-246 818.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GAX26213.1 - 0.00078 18.1 0.0 0.0013 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Hydrolase_6 PF13344.6 GAX26214.1 - 7.1e-21 74.2 0.0 1.8e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX26214.1 - 1.7e-14 53.6 0.0 1.9e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 GAX26214.1 - 8.9e-13 48.7 0.0 8.7e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX26214.1 - 2.4e-09 37.8 0.0 0.00029 21.2 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAX26214.1 - 0.00018 21.2 0.0 0.037 13.6 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase DUF1697 PF08002.11 GAX26214.1 - 0.13 12.7 0.0 2.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) LTD PF00932.19 GAX26216.1 - 9.2e-08 32.4 0.1 3.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Lamin Tail Domain Exo_endo_phos PF03372.23 GAX26216.1 - 0.0082 15.7 1.1 0.021 14.4 1.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2193 PF09959.9 GAX26216.1 - 0.091 11.2 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) HYR PF02494.16 GAX26217.1 - 3.7e-17 62.4 14.8 1.1e-08 35.3 0.7 4.1 6 0 0 6 6 6 2 HYR domain VWA_2 PF13519.6 GAX26217.1 - 1.7e-05 25.4 0.1 3.4e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF5011 PF16403.5 GAX26217.1 - 0.061 13.5 0.0 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Cadherin_5 PF17892.1 GAX26217.1 - 1.7 8.7 5.6 2.6 8.1 0.7 3.5 3 1 1 4 4 4 0 Cadherin-like domain 2-Hacid_dh_C PF02826.19 GAX26218.1 - 0.0093 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FIST PF08495.10 GAX26218.1 - 0.083 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 FIST N domain SKN1 PF03935.15 GAX26219.1 - 2.7e-66 224.0 12.3 3.4e-52 177.5 3.9 3.3 3 1 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) EGF_2 PF07974.13 GAX26219.1 - 0.0035 17.7 14.0 0.0035 17.7 14.0 2.9 3 0 0 3 3 3 1 EGF-like domain EB PF01683.18 GAX26219.1 - 0.0055 17.0 3.9 0.0055 17.0 3.9 2.2 2 0 0 2 2 2 1 EB module Glyco_hydro_16 PF00722.21 GAX26219.1 - 0.015 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 DUF1223 PF06764.11 GAX26219.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) hEGF PF12661.7 GAX26219.1 - 3.3 8.5 12.6 0.096 13.3 3.3 3.2 3 0 0 3 3 3 0 Human growth factor-like EGF tRNA_int_endo PF01974.17 GAX26220.1 - 2.7e-05 24.1 0.0 7.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Carb_anhydrase PF00194.21 GAX26221.1 - 7.4e-19 68.3 0.2 4.9e-14 52.5 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase Rpn9_C PF18261.1 GAX26221.1 - 0.079 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix Dus PF01207.17 GAX26223.1 - 2.3e-49 168.2 0.0 1.6e-48 165.4 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TPT PF03151.16 GAX26224.1 - 2.2e-14 53.5 3.5 2.7e-14 53.2 3.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX26224.1 - 1.7e-11 44.5 20.0 6.8e-09 36.0 9.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAX26224.1 - 4.5e-10 39.2 6.8 7e-10 38.6 6.8 1.3 1 1 0 1 1 1 1 UAA transporter family TMF_TATA_bd PF12325.8 GAX26226.1 - 0.002 18.3 22.0 0.0045 17.2 8.7 2.7 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding ING PF12998.7 GAX26226.1 - 0.0096 16.5 0.3 0.0096 16.5 0.3 3.0 2 1 1 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding Tropomyosin PF00261.20 GAX26226.1 - 0.027 13.9 26.7 0.058 12.8 26.7 1.6 1 1 0 1 1 1 0 Tropomyosin Med10 PF09748.9 GAX26226.1 - 0.066 13.2 8.1 1.5 8.8 8.1 2.1 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DUF2004 PF09406.10 GAX26226.1 - 0.068 13.5 1.2 0.35 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) NPV_P10 PF05531.12 GAX26226.1 - 0.22 12.0 6.4 24 5.5 3.7 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 GAX26226.1 - 0.5 10.4 25.2 5.2 7.1 3.5 4.0 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 GAX26226.1 - 0.52 10.4 13.5 1.5 8.8 3.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HOOK PF05622.12 GAX26226.1 - 0.85 7.7 25.5 0.082 11.0 6.5 3.0 1 1 2 3 3 3 0 HOOK protein HIP1_clath_bdg PF16515.5 GAX26226.1 - 1 10.0 26.0 0.45 11.1 4.4 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIVA PF05103.13 GAX26226.1 - 1.1 9.3 21.7 0.16 12.0 13.2 3.0 2 1 0 3 3 3 0 DivIVA protein UPF0242 PF06785.11 GAX26226.1 - 1.5 8.9 21.2 1.1e+02 2.9 21.2 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_int_SAM_2 PF12834.7 GAX26226.1 - 2.2 9.0 7.2 1.5 9.5 0.5 3.3 2 2 0 3 3 3 0 Phage integrase, N-terminal Cas_DxTHG PF09455.10 GAX26226.1 - 3 7.4 7.5 3.7 7.0 7.5 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Prefoldin PF02996.17 GAX26226.1 - 3.1 7.7 17.5 0.48 10.3 1.4 3.4 2 1 1 3 3 3 0 Prefoldin subunit Sec20 PF03908.13 GAX26226.1 - 3.9 7.5 9.8 5.9 6.9 0.3 2.9 2 1 0 3 3 3 0 Sec20 DUF2913 PF11140.8 GAX26226.1 - 5.9 6.6 12.5 0.31 10.7 2.2 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2913) TPR_MLP1_2 PF07926.12 GAX26226.1 - 6.7 6.8 29.5 1.6 8.8 7.5 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 GAX26226.1 - 8.4 6.6 30.3 14 5.9 1.3 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 GAX26226.1 - 8.6 6.8 19.2 0.76 10.2 1.2 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SNF2_N PF00176.23 GAX26228.1 - 4.4e-56 190.1 0.1 9.4e-56 189.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX26228.1 - 1.9e-17 63.6 0.0 4.8e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 GAX26228.1 - 3.5e-12 46.0 2.4 5.5e-05 23.0 0.2 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 GAX26228.1 - 9.4e-07 29.0 0.0 9.3e-06 25.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX26228.1 - 0.00029 20.6 0.2 0.0042 16.9 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAX26228.1 - 0.00032 20.0 0.0 0.0009 18.5 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 GAX26228.1 - 0.0033 17.1 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Polysacc_deac_1 PF01522.21 GAX26229.1 - 1.8e-10 40.8 0.2 0.00094 19.1 0.0 3.2 3 1 0 3 3 3 2 Polysaccharide deacetylase DUF2922 PF11148.8 GAX26229.1 - 0.11 12.3 0.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) CXCXC PF03128.14 GAX26229.1 - 0.12 12.9 15.8 0.56 10.8 4.4 3.2 2 0 0 2 2 2 0 CXCXC repeat DUF2517 PF10725.9 GAX26229.1 - 0.17 11.7 0.2 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) NAD_synthase PF02540.17 GAX26230.1 - 0.0036 16.5 0.0 0.0089 15.2 0.0 1.7 1 1 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 GAX26230.1 - 0.022 13.6 0.1 0.06 12.1 0.1 1.8 2 1 0 2 2 2 0 tRNA methyl transferase Asn_synthase PF00733.21 GAX26230.1 - 0.035 13.8 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase SAICAR_synt PF01259.18 GAX26231.1 - 3.9e-75 252.7 0.0 5.2e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase DUF659 PF04937.15 GAX26232.1 - 2.5e-09 37.1 0.0 5.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ank_5 PF13857.6 GAX26233.1 - 3.7e-10 39.8 0.1 2.8e-05 24.3 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX26233.1 - 2.8e-06 27.8 0.1 0.021 15.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAX26233.1 - 0.017 15.6 2.9 9.5 6.9 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat Ank_3 PF13606.6 GAX26233.1 - 0.023 15.2 0.9 6.2 7.7 0.1 4.3 5 1 0 5 5 5 0 Ankyrin repeat SRRM_C PF15230.6 GAX26233.1 - 0.065 13.8 4.8 0.14 12.8 4.8 1.4 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus tRNA-synt_His PF13393.6 GAX26234.1 - 3.2e-32 112.0 0.0 6.7e-32 111.0 0.0 1.6 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 GAX26234.1 - 4.9e-06 26.6 0.0 5.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAX26234.1 - 3.9e-05 23.7 0.0 7.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Mnd1 PF03962.15 GAX26234.1 - 0.13 12.6 0.0 8.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Mnd1 HTH domain LytR_C PF13399.6 GAX26235.1 - 0.091 13.8 1.1 0.28 12.2 1.1 1.8 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Ribonuc_P_40 PF08584.11 GAX26235.1 - 0.23 10.7 1.2 0.39 9.9 1.0 1.5 1 1 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DUF4551 PF15087.6 GAX26235.1 - 1.9 7.2 7.8 2.8 6.7 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GREB1 PF15782.5 GAX26235.1 - 7.3 3.6 8.1 9.8 3.1 8.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Thioredoxin PF00085.20 GAX26236.1 - 1.6e-10 40.9 0.0 3.1e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX26236.1 - 0.0016 18.8 0.0 0.0095 16.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.6 GAX26236.1 - 0.0059 16.8 0.9 0.029 14.5 0.9 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX26236.1 - 0.032 14.7 0.3 0.11 12.9 0.0 2.1 2 1 0 2 2 2 0 Thioredoxin-like domain URO-D PF01208.17 GAX26237.1 - 5.5e-106 354.6 0.0 6.7e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) HYR PF02494.16 GAX26238.1 - 1.3e-46 156.8 54.7 7.3e-11 42.2 1.9 7.0 7 0 0 7 7 7 6 HYR domain Cadherin_5 PF17892.1 GAX26238.1 - 2.5e-11 43.4 24.4 0.011 15.7 0.2 6.6 6 0 0 6 6 6 5 Cadherin-like domain DUF5011 PF16403.5 GAX26238.1 - 2.5e-06 27.5 0.1 0.52 10.5 0.0 5.3 5 0 0 5 5 5 1 Domain of unknown function (DUF5011) SYCP2_SLD PF18584.1 GAX26238.1 - 0.00013 22.1 0.6 34 4.7 0.0 5.2 5 0 0 5 5 5 0 Synaptonemal complex 2 Spt16M-like domain Big_3_2 PF12245.8 GAX26238.1 - 0.067 13.5 5.6 10 6.4 0.1 4.7 5 0 0 5 5 5 0 Bacterial Ig-like domain DUF4307 PF14155.6 GAX26238.1 - 0.076 12.9 10.3 13 5.7 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF4307) DUF1583 PF07622.11 GAX26238.1 - 0.12 11.1 1.0 13 4.5 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1583) zinc_ribbon_9 PF14369.6 GAX26238.1 - 0.35 11.2 20.5 5.4 7.4 1.0 6.2 5 0 0 5 5 5 0 zinc-ribbon Spindle_Spc25 PF08234.12 GAX26238.1 - 0.56 10.5 2.4 1.7e+02 2.5 0.0 3.9 4 0 0 4 4 4 0 Chromosome segregation protein Spc25 DUF4336 PF14234.6 GAX26239.1 - 9.9e-106 353.5 0.1 1.3e-105 353.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) Acetyltransf_1 PF00583.25 GAX26240.1 - 4.6e-12 46.2 0.0 7.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX26240.1 - 6.4e-10 39.0 0.0 2.6e-09 37.1 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX26240.1 - 1.2e-08 35.2 0.0 2.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX26240.1 - 1.5e-07 31.3 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAX26240.1 - 8.8e-06 26.4 0.0 1.2e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAX26240.1 - 0.0039 17.3 0.0 0.0053 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAX26240.1 - 0.018 14.7 0.0 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 GAX26240.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX26240.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AAA_23 PF13476.6 GAX26241.1 - 3.4e-27 96.2 0.6 3.4e-27 96.2 0.6 6.6 2 2 4 6 6 1 1 AAA domain SMC_N PF02463.19 GAX26241.1 - 4.1e-08 32.9 0.0 4.1e-08 32.9 0.0 2.8 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX26241.1 - 2.2e-05 24.3 8.8 2.2e-05 24.3 8.8 5.5 2 2 2 4 4 2 2 AAA ATPase domain DHR10 PF18595.1 GAX26241.1 - 0.00018 21.5 6.3 0.00018 21.5 6.3 11.1 5 3 5 11 11 7 1 Designed helical repeat protein 10 domain AAA_21 PF13304.6 GAX26241.1 - 0.00027 20.8 12.7 0.0017 18.2 0.0 4.0 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAX26241.1 - 0.0017 18.5 0.1 0.013 15.7 0.0 2.4 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 GAX26241.1 - 0.0027 18.0 0.0 0.02 15.1 0.0 2.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAX26241.1 - 0.0082 16.1 0.0 0.035 14.0 0.0 2.2 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 GAX26241.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAX26241.1 - 0.03 13.9 0.3 0.21 11.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain REF PF05755.12 GAX26241.1 - 0.045 13.6 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) ThiF PF00899.21 GAX26241.1 - 0.096 12.0 1.3 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 ThiF family EFG_C PF00679.24 GAX26241.1 - 0.11 12.6 0.9 0.81 9.8 0.1 2.8 2 0 0 2 2 2 0 Elongation factor G C-terminus TMF_TATA_bd PF12325.8 GAX26241.1 - 0.12 12.6 0.1 0.12 12.6 0.1 11.4 4 2 5 12 12 11 0 TATA element modulatory factor 1 TATA binding AAA_22 PF13401.6 GAX26241.1 - 0.52 10.6 3.7 2.2 8.5 0.1 3.5 2 0 0 2 2 2 0 AAA domain ACOX PF01756.19 GAX26242.1 - 2.3e-49 167.4 0.1 2.3e-49 167.4 0.1 2.3 2 1 1 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAX26242.1 - 6.4e-35 120.4 0.0 1.6e-34 119.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAX26242.1 - 2.1e-12 47.1 0.0 5.3e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Resolvase PF00239.21 GAX26242.1 - 0.065 13.3 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 Resolvase, N terminal domain SnoaL_2 PF12680.7 GAX26243.1 - 1.6e-11 44.7 0.1 2.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like domain Sulfotransfer_1 PF00685.27 GAX26244.1 - 0.001 18.6 1.4 0.0086 15.6 1.0 2.6 1 1 1 2 2 2 1 Sulfotransferase domain GrpE PF01025.19 GAX26245.1 - 2.9e-34 118.1 1.6 3.7e-34 117.8 1.6 1.1 1 0 0 1 1 1 1 GrpE TPR_MLP1_2 PF07926.12 GAX26245.1 - 0.0029 17.7 1.8 0.0053 16.8 1.8 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein OmpH PF03938.14 GAX26245.1 - 0.039 14.3 3.5 0.058 13.7 3.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SKA2 PF16740.5 GAX26245.1 - 0.088 12.6 2.0 1.1 9.0 2.0 2.2 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF1043 PF06295.12 GAX26245.1 - 0.09 12.8 0.5 0.16 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) ATP-synt_DE PF00401.20 GAX26245.1 - 0.2 11.9 4.6 2 8.7 4.6 2.3 1 1 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Gar1 PF04410.14 GAX26246.1 - 0.024 14.4 0.3 0.042 13.6 0.3 1.4 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region PPR_2 PF13041.6 GAX26247.1 - 1.3e-05 25.3 0.0 0.54 10.5 0.0 5.3 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.6 GAX26247.1 - 0.0012 18.9 0.0 5.1 7.2 0.0 4.8 6 1 1 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.20 GAX26247.1 - 0.0014 18.7 2.0 3.1 8.3 0.0 5.9 8 1 0 8 8 8 1 PPR repeat PPR_1 PF12854.7 GAX26247.1 - 0.033 13.9 0.8 1.5 8.6 0.0 3.7 5 0 0 5 5 5 0 PPR repeat Glycos_transf_2 PF00535.26 GAX26248.1 - 2e-15 57.0 0.3 2.5e-14 53.4 0.3 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX26248.1 - 0.0002 21.3 0.1 0.44 10.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GAX26248.1 - 0.022 15.3 1.9 0.31 11.6 0.6 3.3 2 2 0 2 2 2 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAX26248.1 - 0.14 11.6 0.0 2.2 7.7 0.0 2.1 1 1 0 1 1 1 0 Glycosyltransferase like family 2 CDC45 PF02724.14 GAX26248.1 - 0.17 10.1 2.1 0.32 9.3 1.0 1.7 2 0 0 2 2 2 0 CDC45-like protein RNB PF00773.19 GAX26250.1 - 2.7e-98 329.3 0.0 4e-98 328.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAX26250.1 - 6.7e-18 64.5 0.0 1.7e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 GAX26250.1 - 3.7e-12 46.7 0.0 9.2e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 PIN domain Rrp44_S1 PF17215.3 GAX26250.1 - 3.4e-08 33.3 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 GAX26250.1 - 4.6e-08 33.1 0.0 5e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain Dis3l2_C_term PF17877.1 GAX26250.1 - 0.0011 19.2 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 GAX26250.1 - 0.0013 18.5 0.0 0.0036 17.0 0.0 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain DUF1736 PF08409.11 GAX26251.1 - 0.0029 17.5 0.1 0.01 15.8 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) AA_permease_2 PF13520.6 GAX26252.1 - 5.3e-45 154.0 26.3 7.5e-45 153.5 26.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAX26252.1 - 9.7e-20 70.6 28.4 3.5e-19 68.8 27.9 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GAX26252.1 - 2.7e-08 33.8 0.2 2.7e-08 33.8 0.2 3.6 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.13 GAX26252.1 - 2e-07 30.2 10.8 1.1e-06 27.7 6.2 3.0 2 1 0 2 2 2 1 Spore germination protein BCHF PF07284.11 GAX26252.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.6 3 0 0 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Phage_holin_3_1 PF05106.12 GAX26252.1 - 0.35 11.3 4.2 2.8 8.4 0.5 3.5 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) DUF2892 PF11127.8 GAX26252.1 - 4.5 7.4 14.4 1.1 9.3 0.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) NUMOD3 PF07460.11 GAX26253.1 - 5.3e-07 29.8 0.4 1.1e-06 28.7 0.4 1.6 1 0 0 1 1 1 1 NUMOD3 motif (2 copies) MRP-S27 PF10037.9 GAX26253.1 - 0.53 9.1 18.2 0.84 8.4 18.2 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF4746 PF15928.5 GAX26253.1 - 1.4 8.3 24.0 0.036 13.5 12.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Het-C PF07217.11 GAX26253.1 - 3.5 6.1 9.3 5.8 5.3 9.3 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C RmlD_sub_bind PF04321.17 GAX26254.1 - 2.1e-13 50.0 0.0 8.5e-13 48.0 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAX26254.1 - 2.5e-10 40.2 0.0 3.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAX26254.1 - 0.00019 20.7 0.0 0.00038 19.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAX26254.1 - 0.0087 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CST-I PF06002.12 GAX26254.1 - 0.051 13.3 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) B12-binding PF02310.19 GAX26254.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain AMP-binding PF00501.28 GAX26255.1 - 3e-88 296.3 0.0 4.1e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 GAX26255.1 - 0.0021 18.3 0.0 0.0069 16.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YdiH PF15930.5 GAX26255.1 - 0.16 12.2 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function T2SSM_b PF10741.9 GAX26256.1 - 0.56 10.0 2.1 13 5.6 0.2 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M subtype b Kri1 PF05178.12 GAX26256.1 - 6.5 7.4 7.0 1.2 9.8 1.9 2.4 2 1 0 2 2 2 0 KRI1-like family RCC1 PF00415.18 GAX26257.1 - 3.5e-40 136.4 23.3 4.4e-07 30.4 0.5 8.3 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX26257.1 - 1.1e-18 66.5 23.8 0.0002 21.1 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Aldo_ket_red PF00248.21 GAX26258.1 - 5.4e-50 170.2 0.0 6.3e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LPMO_10 PF03067.15 GAX26259.1 - 0.098 13.3 1.8 8 7.1 0.3 2.1 1 1 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Linocin_M18 PF04454.12 GAX26259.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Syndecan PF01034.20 GAX26260.1 - 0.15 12.0 1.1 0.27 11.2 0.9 1.5 1 1 0 1 1 1 0 Syndecan domain CPSF_A PF03178.15 GAX26261.1 - 4e-63 213.7 0.0 8.1e-44 150.2 0.0 3.4 4 0 0 4 4 4 2 CPSF A subunit region MMS1_N PF10433.9 GAX26261.1 - 2.5e-59 201.2 0.0 1.6e-58 198.5 0.0 2.2 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term HMG_box PF00505.19 GAX26262.1 - 4.9e-08 33.3 2.3 3e-05 24.3 0.6 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX26262.1 - 2.2e-05 25.0 2.1 0.0056 17.3 0.4 2.4 1 1 1 2 2 2 2 HMG-box domain TED_complement PF07678.14 GAX26262.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain PALP PF00291.25 GAX26263.1 - 2.5e-74 250.3 2.1 3e-74 250.1 2.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 GAX26263.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GAX26263.1 - 0.074 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 ACT domain TctA PF01970.16 GAX26264.1 - 0.0018 17.1 4.7 0.0022 16.8 4.7 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family COPI_assoc PF08507.10 GAX26264.1 - 0.19 11.8 14.7 0.64 10.1 14.7 1.7 1 1 0 1 1 1 0 COPI associated protein Glycolytic PF00274.19 GAX26265.1 - 2.5e-110 368.5 0.0 2.8e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF1576 PF07613.11 GAX26266.1 - 0.00036 20.1 0.1 0.0005 19.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1576) Hydrolase_4 PF12146.8 GAX26267.1 - 1.7e-07 30.8 0.1 3e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX26267.1 - 0.0022 17.7 0.4 0.0045 16.7 0.4 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B_2 PF12706.7 GAX26267.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SepSecS PF05889.13 GAX26268.1 - 5.3e-114 380.9 0.0 6.3e-114 380.7 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 GAX26268.1 - 6e-06 25.8 0.0 8.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAX26268.1 - 0.00014 21.2 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 GAX26268.1 - 0.013 14.3 2.2 0.18 10.5 1.0 2.0 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain DotU PF09850.9 GAX26268.1 - 0.036 13.8 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF4506 PF14958.6 GAX26269.1 - 0.0012 18.3 0.0 0.0059 16.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4506) HemX PF04375.14 GAX26269.1 - 0.017 14.4 15.7 0.025 13.9 15.7 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DivIC PF04977.15 GAX26269.1 - 0.019 14.7 7.2 0.019 14.7 7.2 2.2 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 GAX26269.1 - 0.028 15.1 8.9 0.028 15.1 8.9 2.3 2 0 0 2 2 2 0 SlyX UPF0242 PF06785.11 GAX26269.1 - 0.036 14.2 14.5 0.064 13.4 14.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TEX13 PF15186.6 GAX26269.1 - 0.12 12.0 10.1 0.2 11.3 10.1 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family BLOC1_2 PF10046.9 GAX26269.1 - 0.17 12.2 11.7 0.67 10.3 11.7 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TFIIA PF03153.13 GAX26269.1 - 0.47 10.4 15.6 0.52 10.3 15.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MHC_II_beta PF00969.19 GAX26269.1 - 0.56 10.3 2.8 5.1 7.3 0.6 2.5 1 1 1 2 2 2 0 Class II histocompatibility antigen, beta domain HisKA PF00512.25 GAX26269.1 - 0.7 10.0 3.8 0.93 9.6 0.7 2.4 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF1216 PF06746.11 GAX26269.1 - 0.72 9.9 12.1 1.2 9.2 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) DUF4407 PF14362.6 GAX26269.1 - 1.9 7.8 7.9 2.4 7.4 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GAX26269.1 - 1.9 8.0 11.0 2.6 7.5 11.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliD_N PF02465.18 GAX26269.1 - 2.5 8.9 12.1 0.37 11.5 6.3 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SET PF00856.28 GAX26270.1 - 4.9e-05 23.8 0.0 0.0015 18.9 0.0 2.4 1 1 0 1 1 1 1 SET domain HMD PF03201.16 GAX26270.1 - 0.14 12.4 0.3 1 9.7 0.0 2.4 2 1 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Kinesin PF00225.23 GAX26272.1 - 3e-88 296.0 0.0 4.9e-88 295.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX26272.1 - 7.9e-16 58.3 0.0 1.6e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 GAX26272.1 - 6.1e-06 26.6 0.1 7.2e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAX26272.1 - 0.00066 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_7 PF12775.7 GAX26272.1 - 0.12 11.8 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM_N PF14551.6 GAX26272.1 - 0.73 10.5 4.7 13 6.4 0.3 3.0 2 1 1 3 3 3 0 MCM N-terminal domain Bac_DNA_binding PF00216.21 GAX26274.1 - 3.4e-28 97.7 0.3 3.4e-28 97.7 0.3 1.4 2 0 0 2 2 2 1 Bacterial DNA-binding protein HU-HIG PF18291.1 GAX26274.1 - 2.2e-06 27.7 0.1 3e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif DUF2267 PF10025.9 GAX26274.1 - 4.4e-05 23.8 0.2 6e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) HU-CCDC81_euk_1 PF14908.6 GAX26274.1 - 0.025 14.7 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 GAX26274.1 - 0.044 13.9 0.3 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 DSBA PF01323.20 GAX26274.1 - 0.08 12.7 0.2 0.1 12.4 0.2 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain HU-CCDC81_bac_2 PF18175.1 GAX26274.1 - 0.2 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 LRR_4 PF12799.7 GAX26275.1 - 1.5e-07 31.6 5.7 0.45 11.0 0.1 5.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX26275.1 - 6.8e-05 22.6 5.8 1.6 8.6 0.0 4.7 3 2 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 GAX26275.1 - 0.068 13.8 6.7 5.6 7.9 0.2 6.0 8 0 0 8 8 8 0 Leucine Rich Repeat DUF5113 PF17140.4 GAX26277.1 - 0.056 13.2 0.5 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) SBBP PF06739.11 GAX26277.1 - 0.089 12.8 10.0 1.1 9.3 0.0 5.5 6 0 0 6 6 6 0 Beta-propeller repeat Baculo_11_kDa PF06143.11 GAX26277.1 - 0.19 11.3 0.2 0.36 10.4 0.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Melibiase PF02065.18 GAX26278.1 - 2.5e-11 43.1 0.0 4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_2 PF16499.5 GAX26278.1 - 0.0041 16.3 0.2 0.011 14.9 0.1 1.7 2 0 0 2 2 2 1 Alpha galactosidase A Raffinose_syn PF05691.12 GAX26278.1 - 0.18 9.6 0.1 0.26 9.0 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 HA PF03457.14 GAX26280.1 - 5.2e-56 186.9 13.2 8e-19 67.7 0.2 3.1 3 0 0 3 3 3 3 Helicase associated domain DUF413 PF04219.12 GAX26280.1 - 0.0094 16.0 0.7 0.22 11.5 0.6 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF ANAPC5 PF12862.7 GAX26281.1 - 1.3e-10 41.2 7.8 9.4e-09 35.2 0.0 4.3 3 1 1 4 4 3 1 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 GAX26281.1 - 0.00013 22.2 6.1 0.00022 21.4 0.7 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAX26281.1 - 0.00013 22.2 12.2 1 9.7 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26281.1 - 0.0002 21.2 2.9 3.3 8.0 0.8 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX26281.1 - 0.0011 18.9 3.0 2.2 8.7 0.5 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX26281.1 - 0.0012 19.2 0.4 9.1 7.2 0.0 4.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX26281.1 - 0.0031 18.0 9.8 3.8 8.4 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX26281.1 - 0.0047 17.4 11.8 0.016 15.7 2.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat Peptidase_C58 PF03543.14 GAX26281.1 - 0.0047 16.7 0.2 0.011 15.5 0.2 1.7 1 0 0 1 1 1 1 Yersinia/Haemophilus virulence surface antigen TPR_1 PF00515.28 GAX26281.1 - 0.0071 16.1 2.8 1.9 8.4 0.6 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX26281.1 - 0.11 13.4 14.8 0.84 10.6 0.3 5.4 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX26281.1 - 0.16 11.6 8.3 1 9.1 3.6 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 GAX26281.1 - 0.83 9.6 11.4 9.8 6.2 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DLH PF01738.18 GAX26282.1 - 9.2e-60 201.9 0.0 1.3e-28 100.1 0.0 2.0 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 GAX26282.1 - 6.6e-07 29.5 3.0 0.024 14.5 0.0 3.3 3 0 0 3 3 3 3 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 GAX26282.1 - 3.3e-06 26.0 0.5 0.1 11.3 0.1 2.9 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 GAX26282.1 - 1.5e-05 24.6 1.2 0.04 13.4 0.2 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1100 PF06500.11 GAX26282.1 - 2.2e-05 23.5 0.0 0.041 12.7 0.0 2.7 3 0 0 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 GAX26282.1 - 0.0015 18.2 0.4 0.091 12.4 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_1 PF00232.18 GAX26284.1 - 1.4e-171 571.0 0.0 1.5e-171 570.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 GAX26284.1 - 0.0027 17.2 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Bap31_Bap29_C PF18035.1 GAX26285.1 - 0.011 15.7 1.6 0.035 14.1 1.6 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 GAX26285.1 - 0.056 13.2 2.4 0.18 11.6 1.4 2.4 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 GAX26285.1 - 1.7 9.3 7.9 0.87 10.3 0.8 3.2 1 1 1 3 3 3 0 Initiation control protein YabA Csm1_N PF18504.1 GAX26285.1 - 1.7 9.0 5.3 2.4 8.6 1.1 3.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 GAX26285.1 - 2.5 6.9 11.5 0.5 9.2 4.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein GIT_CC PF16559.5 GAX26285.1 - 4.3 7.3 10.0 0.62 10.0 2.5 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 GAX26285.1 - 8.8 6.9 10.7 13 6.3 8.5 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region MORN PF02493.20 GAX26286.1 - 1.3e-38 128.6 50.5 3.2e-08 33.0 0.2 7.7 7 0 0 7 7 7 7 MORN repeat Tudor_2 PF18104.1 GAX26286.1 - 3.2 7.5 7.4 8.8 6.1 0.1 4.0 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain DUF997 PF06196.12 GAX26287.1 - 0.094 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF997) UPF0051 PF01458.17 GAX26288.1 - 7.1e-49 166.4 0.0 2.2e-48 164.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein family (UPF0051) HMG_box PF00505.19 GAX26290.1 - 1.3e-06 28.7 1.4 1.6e-05 25.2 0.1 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX26290.1 - 1.4e-05 25.6 0.8 7.4e-05 23.3 0.8 2.2 1 1 0 1 1 1 1 HMG-box domain MlaC PF05494.12 GAX26290.1 - 0.031 14.0 1.7 0.059 13.1 0.0 2.3 3 0 0 3 3 3 0 MlaC protein AP2 PF00847.20 GAX26291.1 - 7.6e-05 22.9 0.3 0.00017 21.7 0.3 1.6 1 0 0 1 1 1 1 AP2 domain RCC1 PF00415.18 GAX26292.1 - 5.6e-37 126.1 18.7 7.8e-09 36.0 0.1 6.3 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX26292.1 - 6.4e-32 108.7 23.4 4.6e-10 39.0 0.6 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 GAX26292.1 - 0.093 13.2 0.1 68 3.9 0.1 3.3 2 1 0 3 3 3 0 SUKH-3 immunity protein DUF1459 PF07312.11 GAX26292.1 - 0.31 11.3 6.2 2 8.7 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) SBDS PF01172.18 GAX26295.1 - 3.4e-28 97.5 0.2 1.1e-27 95.9 0.2 1.9 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 GAX26295.1 - 1.7e-20 73.2 0.0 5.6e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 SBDS protein C-terminal domain zf-C2H2 PF00096.26 GAX26295.1 - 0.21 12.1 0.2 0.21 12.1 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type PGA2 PF07543.12 GAX26295.1 - 0.26 11.3 8.9 0.48 10.4 8.9 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 CMS1 PF14617.6 GAX26295.1 - 0.28 10.5 9.1 0.24 10.7 6.8 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ferlin_C PF16165.5 GAX26295.1 - 0.3 11.0 1.3 0.57 10.1 1.3 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Rubella_Capsid PF05750.11 GAX26295.1 - 0.32 10.6 2.5 0.51 9.9 2.5 1.3 1 0 0 1 1 1 0 Rubella capsid protein CCDC106 PF15794.5 GAX26295.1 - 0.56 9.9 12.3 1.1 9.0 12.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 UPF0239 PF06783.11 GAX26295.1 - 8.4 6.6 7.8 31 4.9 7.8 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Aminotran_5 PF00266.19 GAX26296.1 - 1.1e-09 37.8 0.0 1.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V YAcAr PF10686.9 GAX26296.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family TGase_elicitor PF16683.5 GAX26296.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase elicitor DLH PF01738.18 GAX26297.1 - 1.8e-27 96.3 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX26297.1 - 0.00025 20.6 0.0 0.0068 15.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 GAX26297.1 - 0.071 12.1 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase Kri1_C PF12936.7 GAX26299.1 - 3.9e-24 84.7 1.3 3.9e-24 84.7 1.3 5.6 4 3 2 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 GAX26299.1 - 4e-20 72.3 11.4 4e-20 72.3 11.4 7.8 6 2 1 7 7 7 1 KRI1-like family PRMT5 PF05185.16 GAX26300.1 - 1.6e-53 181.1 0.0 7.6e-53 178.9 0.0 1.9 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GAX26300.1 - 6.1e-32 110.9 0.1 1.9e-31 109.3 0.1 1.8 1 1 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 GAX26300.1 - 6e-16 58.4 0.0 1.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Methyltransf_25 PF13649.6 GAX26300.1 - 0.0034 18.0 0.1 0.014 16.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PALP PF00291.25 GAX26300.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Met_10 PF02475.16 GAX26300.1 - 0.035 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein His_Phos_1 PF00300.22 GAX26301.1 - 3.1e-33 115.1 0.0 1e-26 93.9 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) HIT PF01230.23 GAX26303.1 - 5.7e-26 91.1 0.0 7.2e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAX26303.1 - 6.4e-21 75.0 0.0 7.6e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDH PF02611.15 GAX26303.1 - 0.05 13.2 0.1 0.095 12.3 0.1 1.4 1 1 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase HA PF03457.14 GAX26304.1 - 6.9e-59 196.1 15.1 2.1e-20 72.8 0.8 4.4 4 0 0 4 4 4 4 Helicase associated domain Gag_p10 PF02337.17 GAX26304.1 - 0.0079 16.1 3.1 2.2 8.3 0.0 4.1 5 0 0 5 5 5 2 Retroviral GAG p10 protein G_glu_transpept PF01019.21 GAX26305.1 - 4.3e-138 461.3 3.3 4e-123 411.9 0.1 2.7 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase NAD_binding_2 PF03446.15 GAX26306.1 - 2.9e-31 108.8 0.8 5.7e-31 107.8 0.8 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAX26306.1 - 3.6e-30 104.7 0.8 6.2e-30 103.9 0.8 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 GAX26306.1 - 0.13 12.2 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MttA_Hcf106 PF02416.16 GAX26307.1 - 0.29 10.5 1.3 0.43 9.9 0.1 2.1 3 1 0 3 3 3 0 mttA/Hcf106 family Ank_2 PF12796.7 GAX26308.1 - 3e-11 43.8 0.0 6.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX26308.1 - 1.1e-07 32.0 0.0 0.0049 17.1 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX26308.1 - 1.7e-07 31.6 0.0 7e-05 23.3 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX26308.1 - 0.0042 17.5 0.0 2.6 8.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAX26308.1 - 0.043 14.3 0.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat YL1 PF05764.13 GAX26308.1 - 0.33 11.0 3.7 0.49 10.5 3.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Metallophos PF00149.28 GAX26309.1 - 1.5e-06 28.8 0.3 3.9e-06 27.5 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 GAX26309.1 - 8.1e-05 23.0 0.1 0.00018 21.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAX26309.1 - 0.00041 20.0 0.1 0.31 11.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAX26309.1 - 0.00061 19.2 0.1 0.24 11.0 0.0 2.5 2 0 0 2 2 2 2 EF hand 5_nucleotid_C PF02872.18 GAX26309.1 - 0.0023 18.2 0.0 0.0051 17.0 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain EF-hand_1 PF00036.32 GAX26309.1 - 0.0029 17.0 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 EF hand Metallophos_2 PF12850.7 GAX26309.1 - 0.077 13.2 0.0 0.88 9.7 0.0 2.6 3 0 0 3 3 3 0 Calcineurin-like phosphoesterase superfamily domain Dockerin_1 PF00404.18 GAX26309.1 - 0.11 12.7 0.4 12 6.2 0.0 2.7 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_8 PF13833.6 GAX26309.1 - 0.12 12.2 0.1 0.38 10.6 0.1 1.8 1 1 0 1 1 1 0 EF-hand domain pair Mito_carr PF00153.27 GAX26310.1 - 1.8e-43 146.4 0.3 1.9e-23 82.2 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Glyco_tranf_2_4 PF13704.6 GAX26311.1 - 0.00067 20.1 1.5 0.0021 18.5 1.5 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 GAX26312.1 - 0.00031 21.2 1.1 0.00085 19.8 1.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 DAGK_cat PF00781.24 GAX26313.1 - 1e-18 67.2 0.1 1.6e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peptidase_S28 PF05577.12 GAX26314.1 - 8.8e-49 166.5 0.0 1.2e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Aldolase PF01081.19 GAX26315.1 - 2.1e-30 105.6 0.0 4.5e-30 104.5 0.1 1.5 1 1 1 2 2 2 1 KDPG and KHG aldolase FAD_binding_3 PF01494.19 GAX26316.1 - 1.2e-19 70.7 0.9 8.2e-09 35.2 0.7 3.4 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.24 GAX26316.1 - 2.5e-08 33.9 0.0 4.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX26316.1 - 3.4e-08 33.1 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX26316.1 - 2.1e-07 31.4 0.0 0.00018 22.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX26316.1 - 1.3e-05 24.3 0.0 0.13 11.1 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 GAX26316.1 - 1.3e-05 24.1 0.1 0.039 12.6 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 GAX26316.1 - 2.6e-05 24.4 0.0 8.7e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAX26316.1 - 0.0001 21.5 0.2 0.042 12.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAX26316.1 - 0.0001 21.7 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX26316.1 - 0.00047 19.4 0.0 0.13 11.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 GAX26316.1 - 0.0011 19.0 0.0 0.0097 15.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAX26316.1 - 0.0055 16.0 0.1 0.014 14.7 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 GAX26316.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus SE PF08491.10 GAX26316.1 - 0.013 14.5 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Amino_oxidase PF01593.24 GAX26316.1 - 0.1 11.9 0.0 10 5.3 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAX26316.1 - 0.19 11.0 0.2 3.4 6.9 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase RSN1_7TM PF02714.15 GAX26317.1 - 1.8e-25 89.8 18.5 3.5e-25 88.8 18.5 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX26317.1 - 2.5e-13 50.1 9.3 8.5e-13 48.3 0.4 3.3 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX26317.1 - 9.9e-12 45.4 0.4 9.9e-12 45.4 0.4 2.8 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Ras PF00071.22 GAX26318.1 - 1.8e-40 138.2 0.1 2.3e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX26318.1 - 6.1e-27 94.2 0.1 1.2e-26 93.3 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX26318.1 - 4.9e-15 55.4 0.0 8.5e-15 54.6 0.1 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX26318.1 - 9.5e-06 25.7 0.0 4.9e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAX26318.1 - 0.0017 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAX26318.1 - 0.0031 17.1 0.2 0.074 12.6 0.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAX26318.1 - 0.0037 16.8 0.5 0.04 13.4 0.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 GAX26318.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Choline_kin_N PF04428.14 GAX26318.1 - 0.038 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Choline kinase N terminus TniB PF05621.11 GAX26318.1 - 0.084 12.3 0.0 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 GAX26319.1 - 3e-42 144.2 0.0 6.7e-42 143.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX26319.1 - 1.5e-10 40.7 0.5 4.4e-10 39.2 0.2 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_2 PF07724.14 GAX26319.1 - 3.9e-06 27.1 0.0 1.2e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX26319.1 - 8.3e-06 25.9 0.1 5e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX26319.1 - 2.3e-05 24.9 0.1 0.00031 21.2 0.1 2.4 2 1 1 3 3 2 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 GAX26319.1 - 7.7e-05 22.6 0.2 0.00019 21.3 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 GAX26319.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX26319.1 - 0.00033 21.0 0.0 0.011 16.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 GAX26319.1 - 0.00037 20.5 0.0 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAX26319.1 - 0.0022 18.2 0.0 0.0055 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DivIC PF04977.15 GAX26319.1 - 0.0023 17.7 0.1 0.0043 16.8 0.1 1.4 1 0 0 1 1 1 1 Septum formation initiator IstB_IS21 PF01695.17 GAX26319.1 - 0.0032 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 GAX26319.1 - 0.0045 16.5 0.1 0.18 11.2 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein TIP49 PF06068.13 GAX26319.1 - 0.0056 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 GAX26319.1 - 0.0071 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAX26319.1 - 0.0076 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAX26319.1 - 0.0076 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAX26319.1 - 0.008 15.9 0.3 0.065 12.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 GAX26319.1 - 0.011 16.3 0.4 0.037 14.6 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 GAX26319.1 - 0.013 15.3 0.0 0.1 12.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GAX26319.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 GAX26319.1 - 0.035 14.4 0.0 0.57 10.5 0.1 2.5 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 GAX26319.1 - 0.038 14.4 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 GAX26319.1 - 0.046 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 GAX26319.1 - 0.052 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 GAX26319.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAX26319.1 - 0.067 12.8 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX26319.1 - 0.082 13.4 0.1 0.72 10.4 0.0 2.4 3 0 0 3 3 2 0 ABC transporter Zeta_toxin PF06414.12 GAX26319.1 - 0.086 12.1 0.0 0.27 10.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 GAX26319.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activ_2 PF14532.6 GAX26319.1 - 0.13 12.4 0.0 0.87 9.7 0.0 2.5 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 GAX26319.1 - 0.19 11.5 0.4 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.31 GAX26320.1 - 1.4e-49 166.1 15.2 4.2e-16 58.9 0.4 4.3 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX26320.1 - 6.8e-40 135.1 8.6 9e-17 61.1 0.1 4.3 3 1 1 4 4 4 4 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAX26320.1 - 2.2e-05 24.5 2.0 1.3 9.2 0.0 3.9 2 1 2 4 4 4 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 GAX26320.1 - 7.1e-05 22.8 2.1 0.13 12.3 0.1 3.2 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 GAX26320.1 - 0.00012 22.0 0.2 0.98 9.5 0.0 3.8 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 GAX26320.1 - 0.039 13.8 1.0 11 6.0 0.0 3.4 2 2 1 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 GAX26320.1 - 0.068 13.6 12.5 0.34 11.3 0.2 4.2 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain DNA_pol_phi PF04931.13 GAX26320.1 - 0.21 9.7 10.7 0.33 9.0 10.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-bind_5 PF13873.6 GAX26320.1 - 0.26 11.4 7.6 10 6.3 0.1 4.2 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Spore_III_AB PF09548.10 GAX26320.1 - 1.5 8.9 3.7 12 6.0 0.0 2.7 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Sigma70_ner PF04546.13 GAX26320.1 - 4.6 7.1 10.4 0.43 10.4 5.4 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Pkinase PF00069.25 GAX26322.1 - 2.5e-61 207.4 0.0 2.9e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26322.1 - 2.9e-21 75.9 0.0 3.9e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX26322.1 - 7.2e-05 22.2 0.2 0.00011 21.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX26322.1 - 0.00013 21.4 0.1 0.062 12.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAX26322.1 - 0.00063 19.7 0.7 0.019 14.9 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX26322.1 - 0.053 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 GAX26322.1 - 0.07 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Tnp_DNA_bind PF14706.6 GAX26322.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DNA-binding FTA2 PF13095.6 GAX26322.1 - 0.13 11.9 0.1 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cnd1 PF12717.7 GAX26322.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Titin_Z PF09042.11 GAX26323.1 - 0.0035 17.2 0.0 0.21 11.5 0.0 3.2 2 1 0 2 2 2 1 Titin Z MMS19_C PF12460.8 GAX26323.1 - 0.01 15.0 0.9 1 8.4 0.2 3.3 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal ParcG PF10274.9 GAX26323.1 - 0.032 14.3 0.0 0.23 11.5 0.0 2.5 2 0 0 2 2 2 0 Parkin co-regulated protein Ipi1_N PF12333.8 GAX26323.1 - 0.12 13.0 1.8 5 7.8 0.4 3.6 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Choline_kin_N PF04428.14 GAX26323.1 - 0.12 12.0 0.0 0.49 10.1 0.0 2.1 1 0 0 1 1 1 0 Choline kinase N terminus Sel1 PF08238.12 GAX26325.1 - 1.8e-09 37.9 1.9 0.011 16.4 0.1 4.5 4 0 0 4 4 4 3 Sel1 repeat 2OG-FeII_Oxy_3 PF13640.6 GAX26325.1 - 3e-05 24.8 0.4 6.6e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 GAX26325.1 - 0.0024 17.8 0.0 7.7 6.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX26325.1 - 0.041 14.1 0.4 15 6.1 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat HMGL-like PF00682.19 GAX26326.1 - 4.9e-54 183.7 0.0 5.6e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 HMGL-like EMP70 PF02990.16 GAX26328.1 - 4.5e-137 457.8 5.7 5.5e-137 457.6 5.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Annexin PF00191.20 GAX26330.1 - 3e-42 142.5 0.2 5.6e-10 39.1 0.0 4.2 4 0 0 4 4 4 4 Annexin DUF747 PF05346.11 GAX26331.1 - 5.7e-79 265.9 13.6 8.4e-79 265.3 13.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF588 PF04535.12 GAX26331.1 - 0.0026 17.5 2.2 1.2 9.0 2.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF588) 60KD_IMP PF02096.20 GAX26331.1 - 2.6 7.9 5.9 11 5.9 0.1 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein bHLH-MYC_N PF14215.6 GAX26332.1 - 2.1e-06 28.1 0.0 5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal FAD_binding_3 PF01494.19 GAX26333.1 - 9.6e-15 54.7 0.4 2.6e-14 53.2 0.4 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAX26333.1 - 0.0016 18.1 0.2 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX26333.1 - 0.018 15.0 0.1 0.05 13.6 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAX26333.1 - 0.024 13.9 0.4 0.13 11.5 0.0 1.8 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX26333.1 - 0.026 14.7 0.0 0.097 12.9 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAX26333.1 - 0.18 12.4 0.2 0.61 10.7 0.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Arm PF00514.23 GAX26334.1 - 3 8.0 9.7 11 6.3 0.0 4.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Citrate_synt PF00285.21 GAX26335.1 - 2.9e-103 345.7 0.0 3.6e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PAS_3 PF08447.12 GAX26335.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF4142 PF13628.6 GAX26335.1 - 0.48 10.6 2.1 14 5.9 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) TCR PF03638.15 GAX26336.1 - 4.2e-31 107.0 72.1 5.2e-11 42.7 18.9 3.2 3 0 0 3 3 3 3 Tesmin/TSO1-like CXC domain, cysteine-rich domain preSET_CXC PF18264.1 GAX26336.1 - 3.3 8.3 73.0 0.082 13.4 18.1 3.8 3 1 0 3 3 3 0 CXC domain AAA_12 PF13087.6 GAX26337.1 - 1.3e-53 181.6 0.0 2.6e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX26337.1 - 8.2e-38 130.7 1.1 6.3e-21 75.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAX26337.1 - 1.5e-09 37.9 0.0 6.1e-06 26.1 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.6 GAX26337.1 - 2.9e-08 34.2 0.0 3.7e-07 30.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 GAX26337.1 - 2.9e-07 30.5 0.0 0.52 10.0 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 GAX26337.1 - 1.2e-05 25.9 0.0 2.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX26337.1 - 0.00025 21.4 0.0 0.0033 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAX26337.1 - 0.00087 19.7 0.1 0.0041 17.5 0.0 2.3 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX26337.1 - 0.0013 19.2 0.2 0.0062 16.9 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 GAX26337.1 - 0.0032 17.4 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 GAX26337.1 - 0.0033 16.9 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 GAX26337.1 - 0.0052 16.5 0.0 0.049 13.4 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 GAX26337.1 - 0.011 15.1 0.0 0.095 12.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 GAX26337.1 - 0.018 15.2 0.3 0.064 13.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAX26337.1 - 0.021 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 GAX26337.1 - 0.022 14.3 0.9 0.079 12.5 0.1 2.3 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 GAX26337.1 - 0.051 13.1 0.3 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain KTI12 PF08433.10 GAX26337.1 - 0.072 12.5 0.2 1.7 8.0 0.2 2.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 GAX26337.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 GAX26337.1 - 0.087 12.1 0.1 0.83 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 GAX26337.1 - 0.088 13.4 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 GAX26337.1 - 0.18 11.6 0.1 0.43 10.4 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain VWA PF00092.28 GAX26339.1 - 6.2e-07 29.8 0.3 8.7e-07 29.3 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAX26339.1 - 8.8e-06 26.3 0.6 1.6e-05 25.5 0.6 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX26339.1 - 0.0058 16.6 0.3 0.0086 16.0 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_N PF08399.11 GAX26339.1 - 0.046 14.2 0.0 0.09 13.3 0.0 1.4 1 0 0 1 1 1 0 VWA N-terminal VWA_CoxE PF05762.14 GAX26339.1 - 0.06 12.7 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF1298 PF06974.13 GAX26340.1 - 3.1e-18 66.1 0.0 8.3e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 GAX26340.1 - 0.18 11.5 1.1 1.3 8.7 0.0 2.4 2 1 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Epimerase PF01370.21 GAX26341.1 - 2.6e-20 72.9 0.1 4e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX26341.1 - 6.3e-20 71.3 0.0 8e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX26341.1 - 4.7e-15 55.5 0.3 7.9e-15 54.7 0.3 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAX26341.1 - 1.2e-13 51.4 0.1 1.6e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAX26341.1 - 1.8e-09 37.4 0.2 3.1e-09 36.7 0.2 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAX26341.1 - 3e-08 33.5 0.1 4.9e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAX26341.1 - 5.3e-07 29.1 0.1 9.2e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAX26341.1 - 9.3e-06 25.7 0.1 2.3e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 GAX26341.1 - 0.0042 16.6 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PrmA PF06325.13 GAX26341.1 - 0.0066 15.9 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RmlD_sub_bind PF04321.17 GAX26341.1 - 0.046 12.8 0.0 0.097 11.8 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Methyltr_RsmB-F PF01189.17 GAX26342.1 - 1e-40 139.5 0.0 1.2e-39 136.1 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 GAX26342.1 - 5e-05 23.9 0.0 0.00018 22.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 GAX26342.1 - 0.00059 20.0 0.0 0.00099 19.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAX26342.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2431 PF10354.9 GAX26342.1 - 0.026 14.8 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) MTS PF05175.14 GAX26342.1 - 0.031 13.8 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain GatB_Yqey PF02637.18 GAX26343.1 - 0.005 16.7 0.0 12 5.8 0.0 3.8 1 1 3 4 4 4 2 GatB domain PDH_E1_M PF17831.1 GAX26343.1 - 0.01 15.4 0.0 9.9 5.6 0.0 3.0 1 1 3 4 4 4 0 Pyruvate dehydrogenase E1 component middle domain Porin_3 PF01459.22 GAX26344.1 - 1e-24 87.5 0.0 1.2e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin N2227 PF07942.12 GAX26344.1 - 0.19 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein PRIMA1 PF16101.5 GAX26344.1 - 0.99 9.5 8.2 1.6 8.8 8.2 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LRR_4 PF12799.7 GAX26345.1 - 6.5e-31 105.9 18.3 4.3e-07 30.1 2.3 6.9 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX26345.1 - 2.2e-26 91.4 19.7 8.4e-11 41.5 0.5 6.4 3 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 GAX26345.1 - 1.7e-12 47.2 9.8 0.00011 21.7 0.4 4.3 1 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 GAX26345.1 - 2.1e-08 33.6 21.4 0.13 12.4 0.0 8.7 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 GAX26345.1 - 0.00027 21.1 15.5 26 5.9 0.0 8.9 8 1 0 8 8 8 1 Leucine Rich Repeat Acyl-CoA_dh_1 PF00441.24 GAX26346.1 - 4.4e-39 134.1 2.8 6.8e-39 133.5 2.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX26346.1 - 1.4e-24 87.0 0.0 3.3e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAX26346.1 - 5.6e-21 74.5 0.1 1.2e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAX26346.1 - 1.6e-15 57.6 0.3 2.9e-15 56.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 GAX26346.1 - 0.044 14.3 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal CK_II_beta PF01214.18 GAX26347.1 - 1.8e-24 86.5 0.0 3e-16 59.8 0.0 2.4 2 0 0 2 2 2 2 Casein kinase II regulatory subunit EGF PF00008.27 GAX26348.1 - 0.00022 21.4 2.8 0.00022 21.4 2.8 4.5 3 1 0 3 3 3 2 EGF-like domain NapE PF06796.11 GAX26348.1 - 0.25 10.9 2.5 0.32 10.6 0.1 2.2 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE TRAP-gamma PF07074.12 GAX26349.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.3 3 0 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LMBR1 PF04791.16 GAX26350.1 - 0.2 10.5 5.2 0.59 9.0 4.5 1.9 1 1 1 2 2 2 0 LMBR1-like membrane protein NUMOD3 PF07460.11 GAX26351.1 - 2e-13 50.3 25.0 1.9e-08 34.4 0.6 5.3 6 0 0 6 6 6 3 NUMOD3 motif (2 copies) CAP18_C PF12153.8 GAX26351.1 - 0.22 11.4 1.3 11 5.9 0.4 2.7 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) SHOCT PF09851.9 GAX26351.1 - 0.59 10.0 12.3 1.8 8.4 0.0 3.7 3 0 0 3 3 3 0 Short C-terminal domain Choline_kinase PF01633.20 GAX26352.1 - 1e-28 100.4 0.0 1.6e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAX26352.1 - 4.1e-13 49.8 1.4 5.9e-13 49.3 0.7 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAX26352.1 - 1.1e-05 25.0 0.1 2.4e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 GAX26352.1 - 0.00012 21.1 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH_6_hur PF04655.14 GAX26352.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.7 2 1 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase_Tyr PF07714.17 GAX26352.1 - 0.036 13.3 0.0 0.11 11.7 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase DHQ_synthase PF01761.20 GAX26353.1 - 1.9e-105 351.8 0.0 2.3e-105 351.5 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 GAX26353.1 - 8.1e-11 42.1 0.2 6.7e-10 39.1 0.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 GAX26353.1 - 5.2e-05 22.2 1.2 0.00021 20.3 1.2 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase VWA_2 PF13519.6 GAX26355.1 - 2.8e-14 53.6 0.2 6.2e-14 52.5 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAX26355.1 - 3.1e-14 53.6 0.0 6.5e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX26355.1 - 4.1e-10 39.8 0.0 1e-09 38.6 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_N PF08399.11 GAX26355.1 - 0.00058 20.3 0.1 0.0015 19.0 0.1 1.7 1 1 0 1 1 1 1 VWA N-terminal VWA_CoxE PF05762.14 GAX26355.1 - 0.0025 17.3 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Orthoreo_P10 PF07204.11 GAX26355.1 - 0.011 15.7 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 dCache_1 PF02743.18 GAX26355.1 - 0.095 12.5 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Cache domain DUF4752 PF15944.5 GAX26355.1 - 0.11 12.5 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) DUF2201 PF09967.9 GAX26355.1 - 0.14 12.3 0.4 0.49 10.5 0.4 2.0 1 1 0 1 1 1 0 VWA-like domain (DUF2201) adh_short_C2 PF13561.6 GAX26357.1 - 1.8e-63 214.2 2.3 2.4e-63 213.8 2.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX26357.1 - 8e-56 188.6 4.4 9.8e-56 188.3 4.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX26357.1 - 7.2e-21 74.9 1.8 1.2e-20 74.1 1.8 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAX26357.1 - 0.00078 18.9 0.0 0.0052 16.2 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 GAX26357.1 - 0.013 15.8 0.5 0.02 15.2 0.5 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RusA PF05866.11 GAX26357.1 - 0.066 13.8 0.4 0.12 12.9 0.4 1.3 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA Chitin_synth_1 PF01644.17 GAX26357.1 - 0.18 11.8 0.2 0.33 10.9 0.2 1.4 1 1 0 1 1 1 0 Chitin synthase Epimerase PF01370.21 GAX26360.1 - 1.5e-17 63.8 0.0 2.6e-16 59.8 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX26360.1 - 3.3e-11 43.2 0.0 1.5e-08 34.4 0.0 3.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase ELFV_dehydrog_N PF02812.18 GAX26361.1 - 1.3e-34 118.9 0.0 2.7e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 GAX26361.1 - 1.1e-33 116.9 0.0 3.4e-33 115.4 0.0 1.8 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 GAX26361.1 - 0.033 14.6 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.25 GAX26362.1 - 4.6e-06 26.2 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain IHHNV_capsid PF16530.5 GAX26363.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid Rhodanese PF00581.20 GAX26365.1 - 8.2e-05 23.1 0.0 0.00023 21.6 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Glyoxalase PF00903.25 GAX26366.1 - 2.2e-08 34.4 0.1 6.6e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAX26366.1 - 5.1e-05 23.5 0.0 0.00015 22.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Adaptin_N PF01602.20 GAX26367.1 - 0.0021 16.7 0.9 0.0021 16.7 0.9 2.9 3 0 0 3 3 3 1 Adaptin N terminal region Paramyx_P_V_C PF03210.13 GAX26367.1 - 0.033 14.0 0.2 0.077 12.8 0.2 1.6 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal DUF2019 PF09450.10 GAX26367.1 - 0.15 12.0 0.6 0.77 9.7 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2019) CARD_2 PF16739.5 GAX26367.1 - 0.74 9.8 2.7 35 4.5 0.0 3.7 3 0 0 3 3 3 0 Caspase recruitment domain Metallophos PF00149.28 GAX26368.1 - 6.6e-34 118.2 0.2 8.5e-34 117.8 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 GAX26368.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain ADH_zinc_N_2 PF13602.6 GAX26369.1 - 9e-07 30.0 0.0 4.1e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAX26369.1 - 8.4e-06 25.8 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CBM_20 PF00686.19 GAX26369.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Starch binding domain NIF PF03031.18 GAX26370.1 - 1.9e-16 60.2 0.0 2.6e-15 56.5 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAX26370.1 - 0.0018 18.7 0.7 0.26 11.7 0.1 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase adh_short PF00106.25 GAX26371.1 - 3.7e-28 98.3 0.0 1.6e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX26371.1 - 3.3e-20 72.6 0.0 6.3e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX26371.1 - 0.0067 16.4 0.2 0.011 15.7 0.2 1.4 1 1 0 1 1 1 1 KR domain Oxidored_nitro PF00148.19 GAX26371.1 - 0.028 13.1 0.0 0.054 12.2 0.0 1.4 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Pyr_redox_2 PF07992.14 GAX26371.1 - 0.07 12.3 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAX26371.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L1 PF00687.21 GAX26372.1 - 6.8e-28 97.8 0.0 9.2e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NYN_YacP PF05991.11 GAX26372.1 - 0.026 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 YacP-like NYN domain RRM_1 PF00076.22 GAX26373.1 - 2.1e-05 24.3 0.0 0.0021 17.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ist1 PF03398.14 GAX26373.1 - 0.27 11.2 3.8 0.68 9.8 3.8 1.6 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Chloroa_b-bind PF00504.21 GAX26374.1 - 2.2e-21 77.0 0.0 3.1e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SRP68 PF16969.5 GAX26375.1 - 4e-66 224.2 17.5 1.7e-38 133.0 17.5 3.0 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 MIT PF04212.18 GAX26375.1 - 0.0028 17.7 0.1 0.014 15.5 0.1 2.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 GAX26376.1 - 7.2e-63 208.8 20.4 9.4e-12 45.1 0.1 9.2 7 1 3 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 GAX26376.1 - 5.6e-57 188.2 15.4 2.5e-09 36.7 0.6 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 GAX26376.1 - 3.7e-44 146.8 8.2 7e-05 22.5 0.1 12.4 12 1 1 13 13 13 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26376.1 - 2.6e-42 139.5 14.4 0.00039 20.3 1.0 11.7 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_8 PF13181.6 GAX26376.1 - 4.3e-29 98.3 17.0 0.00064 19.7 0.1 12.0 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX26376.1 - 2.5e-23 83.0 3.3 9.1e-11 41.7 1.0 5.2 3 2 2 5 5 5 4 MalT-like TPR region TPR_7 PF13176.6 GAX26376.1 - 4.8e-22 76.3 17.3 0.013 15.4 0.0 11.6 11 2 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAX26376.1 - 7.7e-22 76.1 11.1 0.28 12.1 0.2 11.9 10 2 2 12 12 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX26376.1 - 3.6e-20 71.4 8.1 0.0016 18.1 0.0 10.1 11 0 0 11 11 11 5 TPR repeat TPR_16 PF13432.6 GAX26376.1 - 2.4e-11 44.1 18.1 0.038 14.6 0.2 8.6 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAX26376.1 - 2.6e-10 40.2 15.4 6.9 7.5 0.0 11.7 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX26376.1 - 7.6e-09 36.0 10.2 0.32 11.5 0.2 8.8 7 2 1 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX26376.1 - 1.6e-08 34.4 1.0 12 6.9 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat SNAP PF14938.6 GAX26376.1 - 3.2e-08 33.4 14.2 0.00016 21.2 0.0 5.7 4 1 2 7 7 7 4 Soluble NSF attachment protein, SNAP DUF2225 PF09986.9 GAX26376.1 - 4.4e-05 23.3 6.5 0.34 10.6 0.4 5.1 2 1 3 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_15 PF13429.6 GAX26376.1 - 0.00053 19.3 10.9 1 8.5 0.0 6.5 4 3 2 7 7 7 2 Tetratricopeptide repeat MIT PF04212.18 GAX26376.1 - 0.0027 17.7 23.1 2.4 8.3 0.0 8.9 8 2 3 11 11 10 2 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 GAX26376.1 - 0.0057 16.9 0.1 14 6.4 0.0 6.1 9 0 0 9 9 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAX26376.1 - 0.019 15.0 9.2 0.2 11.7 0.0 5.1 4 2 1 6 6 6 0 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 GAX26376.1 - 0.086 12.5 16.6 10 5.8 0.2 7.0 5 2 0 6 6 6 0 Tetratricopeptide repeat-like domain DUF4810 PF16068.5 GAX26376.1 - 0.11 13.1 8.3 3.4 8.3 0.5 4.8 5 1 0 5 5 3 0 Domain of unknown function (DUF4810) RPN7 PF10602.9 GAX26376.1 - 0.34 10.6 21.8 0.58 9.9 0.1 7.6 3 1 2 7 7 7 0 26S proteasome subunit RPN7 DcpS_C PF11969.8 GAX26377.1 - 5.8e-20 71.9 0.3 1.1e-19 71.0 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding NMT1 PF09084.11 GAX26377.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like DUF4743 PF15916.5 GAX26378.1 - 0.22 11.5 2.4 0.4 10.7 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) Syja_N PF02383.18 GAX26381.1 - 0.022 14.1 0.0 1.9 7.7 0.1 2.1 1 1 1 2 2 2 0 SacI homology domain BLOC1S3 PF15753.5 GAX26381.1 - 0.069 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4240 PF14024.6 GAX26381.1 - 0.14 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Hydrolase_like PF13242.6 GAX26382.1 - 2.9e-14 52.9 0.0 6.3e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 GAX26382.1 - 2.9e-11 43.4 0.0 7.6e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAX26382.1 - 4e-10 40.3 0.0 6.6e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX26382.1 - 4e-10 40.1 0.0 4.9e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Ras PF00071.22 GAX26383.1 - 4.8e-64 214.8 0.1 5.8e-64 214.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX26383.1 - 6.5e-36 123.2 0.1 9.3e-36 122.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX26383.1 - 2.7e-18 66.0 0.1 3.4e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAX26383.1 - 5.3e-07 29.2 0.1 6.6e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX26383.1 - 3.2e-06 26.8 0.3 7.4e-06 25.6 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAX26383.1 - 0.00041 19.8 0.1 0.00052 19.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAX26383.1 - 0.00067 19.7 0.1 0.00097 19.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX26383.1 - 0.0022 17.9 0.1 1.5 8.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 GAX26383.1 - 0.032 14.0 0.1 0.093 12.5 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 GAX26383.1 - 0.081 12.6 0.1 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 GAX26383.1 - 0.087 12.3 0.0 0.33 10.5 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 GAX26383.1 - 0.092 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 GAX26383.1 - 0.14 12.5 0.0 0.33 11.4 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX26383.1 - 0.16 12.3 0.0 0.37 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain SSF PF00474.17 GAX26385.1 - 2.4e-07 30.0 9.7 2.4e-07 30.0 9.7 2.2 2 0 0 2 2 2 1 Sodium:solute symporter family DUF3742 PF12553.8 GAX26385.1 - 0.033 14.3 0.6 0.033 14.3 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3742) Ribosomal_60s PF00428.19 GAX26385.1 - 0.034 14.7 1.2 0.071 13.7 1.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein RAMP4 PF06624.12 GAX26385.1 - 0.08 13.0 0.6 0.23 11.5 0.6 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 C2 PF00168.30 GAX26386.1 - 1.6e-25 89.4 0.0 6e-13 49.0 0.0 3.3 3 0 0 3 3 3 2 C2 domain DCP2 PF05026.13 GAX26387.1 - 8.7e-22 77.2 1.1 1.9e-21 76.1 1.1 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 GAX26387.1 - 4.8e-13 49.3 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Dsh_C PF12316.8 GAX26387.1 - 0.15 12.4 5.0 4.8 7.5 0.5 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal ORC6 PF05460.13 GAX26387.1 - 0.5 9.6 6.7 0.72 9.1 0.3 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DENN PF02141.21 GAX26388.1 - 8.3e-31 107.4 0.6 1.5e-30 106.5 0.6 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAX26388.1 - 2.9e-13 50.3 2.7 7.6e-13 49.0 0.4 2.7 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 GAX26388.1 - 2.4e-08 33.9 0.1 2.4e-08 33.9 0.1 2.1 2 0 0 2 2 2 1 dDENN domain tRNA-synt_2d PF01409.20 GAX26389.1 - 9.7e-57 192.2 0.0 1.4e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 GAX26389.1 - 1.2e-24 86.5 0.0 2.3e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain HlyIII PF03006.20 GAX26390.1 - 4.3e-34 118.2 15.1 5e-34 118.0 15.1 1.0 1 0 0 1 1 1 1 Haemolysin-III related VIT1 PF01988.19 GAX26390.1 - 0.84 9.5 4.4 1.7 8.5 4.4 1.4 1 0 0 1 1 1 0 VIT family ERp29 PF07749.12 GAX26391.1 - 0.016 16.1 4.5 0.016 16.1 4.5 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain RasGAP_C PF03836.15 GAX26391.1 - 2.3 8.4 15.2 15 5.7 15.2 2.3 1 1 0 1 1 1 0 RasGAP C-terminus Prominin PF05478.11 GAX26391.1 - 8.5 4.2 12.1 13 3.6 11.0 1.6 1 1 0 1 1 1 0 Prominin Gin PF10764.9 GAX26392.1 - 1.3 9.1 4.3 30 4.7 2.2 3.1 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin CN_hydrolase PF00795.22 GAX26393.1 - 7e-51 173.1 0.0 1.1e-50 172.4 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase TAXi_N PF14543.6 GAX26394.1 - 2.4e-19 70.2 1.0 3.7e-19 69.6 1.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX26394.1 - 1.6e-13 50.8 0.0 3.9e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX26394.1 - 2.4e-07 30.7 0.0 7.8e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal GH115_C PF17829.1 GAX26394.1 - 0.11 12.4 0.0 0.37 10.6 0.0 1.9 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain ATP_bind_1 PF03029.17 GAX26395.1 - 5.1e-73 245.8 0.0 1.5e-71 241.0 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 GAX26395.1 - 0.0024 17.6 0.0 0.068 12.9 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 GAX26395.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX26395.1 - 0.0038 17.8 0.0 0.012 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX26395.1 - 0.0046 17.4 0.0 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 GAX26395.1 - 0.0072 15.9 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAX26395.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX26395.1 - 0.027 14.2 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX26395.1 - 0.055 13.4 0.0 16 5.4 0.0 2.9 2 1 1 3 3 3 0 RsgA GTPase AAA_17 PF13207.6 GAX26395.1 - 0.07 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAX26395.1 - 0.076 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 GAX26395.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GAX26395.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 GAX26395.1 - 0.21 11.1 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ank_2 PF12796.7 GAX26396.1 - 4.8e-32 110.4 3.2 1.8e-08 34.8 0.2 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX26396.1 - 2.3e-24 85.4 4.2 1e-10 41.9 0.1 5.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX26396.1 - 7.1e-22 75.1 3.0 1.7e-05 24.8 0.0 7.2 7 1 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 GAX26396.1 - 3.7e-18 65.1 3.0 0.00012 22.4 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 GAX26396.1 - 1.2e-14 54.1 4.9 3.5e-05 24.0 0.2 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Tricorn_C1 PF14684.6 GAX26400.1 - 4.4e-24 84.3 0.9 8e-24 83.5 0.9 1.4 1 0 0 1 1 1 1 Tricorn protease C1 domain Peptidase_S41 PF03572.18 GAX26400.1 - 1.6e-19 70.1 0.0 2.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GAX26400.1 - 8.7e-08 31.9 0.2 8.7e-08 31.9 0.2 2.5 3 0 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 GAX26400.1 - 3e-05 23.9 0.0 6.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 GAX26400.1 - 6.5e-05 23.2 0.0 0.00027 21.2 0.0 2.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX26400.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain TAT_ubiq PF07706.12 GAX26400.1 - 0.13 12.4 1.6 0.23 11.7 0.2 2.2 2 0 0 2 2 2 0 Aminotransferase ubiquitination site ATP-grasp_3 PF02655.14 GAX26401.1 - 8.4e-09 35.7 0.0 6.9e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GAX26401.1 - 7.5e-05 22.3 0.0 0.00019 21.0 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 GAX26401.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus Pirin_C PF05726.13 GAX26402.1 - 6.1e-14 52.2 0.0 5.2e-13 49.2 0.0 2.3 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Pirin PF02678.16 GAX26402.1 - 2.6e-12 46.7 3.3 6e-10 39.1 3.3 2.4 1 1 0 1 1 1 1 Pirin GST_N_2 PF13409.6 GAX26403.1 - 4.5e-12 46.1 0.0 1.5e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX26403.1 - 5.7e-12 45.5 0.0 1.5e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAX26403.1 - 2.1e-07 31.1 0.0 6.5e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX26403.1 - 0.0003 20.9 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX26403.1 - 0.00064 20.1 0.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain rve PF00665.26 GAX26404.1 - 0.044 14.0 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain GRIP PF01465.20 GAX26405.1 - 5.5e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 GRIP domain ANAPC3 PF12895.7 GAX26405.1 - 0.019 15.2 2.9 1.9 8.7 0.2 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ESP PF16590.5 GAX26405.1 - 3.1 8.1 6.7 16 5.9 1.6 3.1 2 2 0 2 2 2 0 Exocrine gland-secreting peptide DUF3679 PF12438.8 GAX26406.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3679) DUF1736 PF08409.11 GAX26407.1 - 7.1e-17 61.2 0.2 2.5e-16 59.4 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) YiaAB PF05360.14 GAX26407.1 - 0.077 13.3 1.3 0.5 10.7 1.3 2.6 1 0 0 1 1 1 0 yiaA/B two helix domain SpoU_methylase PF00588.19 GAX26409.1 - 8.4e-24 84.4 0.0 1.8e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF3524 PF12038.8 GAX26409.1 - 2.6e-20 72.9 0.1 4.4e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 GAX26409.1 - 1.7e-11 44.0 0.0 3.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 LSM PF01423.22 GAX26410.1 - 2.6e-10 39.8 0.6 4.8e-10 39.0 0.1 1.7 2 0 0 2 2 2 1 LSM domain PAC4 PF16093.5 GAX26410.1 - 0.097 12.9 0.2 31 4.9 0.1 2.8 2 1 1 3 3 3 0 Proteasome assembly chaperone 4 DUF3584 PF12128.8 GAX26411.1 - 0.0055 14.3 40.1 0.007 14.0 40.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ERM PF00769.19 GAX26411.1 - 0.2 11.4 51.2 0.086 12.6 18.9 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HMMR_N PF15905.5 GAX26411.1 - 4.2 6.8 38.9 0.34 10.3 19.8 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Bacillus_HBL PF05791.11 GAX26411.1 - 4.4 7.1 21.4 0.22 11.4 3.9 3.3 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) IFT57 PF10498.9 GAX26411.1 - 4.5 6.1 33.4 2.7 6.9 9.1 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4144 PF13642.6 GAX26411.1 - 4.6 7.9 11.2 1.2 9.8 5.4 2.7 1 1 1 2 2 2 0 protein structure with unknown function PI3K_P85_iSH2 PF16454.5 GAX26411.1 - 5.7 6.5 41.1 0.31 10.6 9.3 3.2 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3107 PF11305.8 GAX26411.1 - 7 7.0 8.7 1.6 9.0 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3107) Pkinase PF00069.25 GAX26412.1 - 2.3e-75 253.4 0.0 4e-75 252.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26412.1 - 6.3e-35 120.7 0.0 1.3e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 GAX26412.1 - 3.6e-13 48.0 1.0 1.2e-05 24.5 0.5 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 GAX26412.1 - 4.8e-12 46.2 3.5 3.6e-05 24.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAX26412.1 - 3.7e-11 42.7 1.1 3.5e-05 23.5 0.5 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX26412.1 - 3.9e-11 41.9 1.7 7e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX26412.1 - 1.1e-10 40.5 1.8 0.00011 21.9 0.0 3.6 2 1 1 3 3 3 2 EF-hand domain APH PF01636.23 GAX26412.1 - 7.4e-06 26.1 0.1 1.5e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX26412.1 - 0.00031 19.7 0.9 0.00066 18.6 0.9 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAX26412.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Peptidase_M43 PF05572.13 GAX26413.1 - 8.8e-17 61.4 0.0 2.1e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX26413.1 - 0.33 11.1 3.8 0.21 11.7 0.3 1.9 1 1 0 2 2 2 0 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 GAX26413.1 - 0.36 10.9 2.3 0.57 10.3 0.2 2.3 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family DUF676 PF05057.14 GAX26414.1 - 0.00021 20.9 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 GAX26414.1 - 0.00056 19.5 0.0 0.00087 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 GAX26414.1 - 0.00067 19.3 0.5 0.022 14.3 0.5 2.2 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Cutinase PF01083.22 GAX26414.1 - 0.0018 18.3 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 GAX26414.1 - 0.0025 18.5 0.0 0.0043 17.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAX26414.1 - 0.0036 17.2 0.0 0.018 14.9 0.0 2.1 2 1 1 3 3 3 1 Lipase (class 3) Abhydrolase_2 PF02230.16 GAX26414.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAX26414.1 - 0.0076 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAX26414.1 - 0.017 15.0 0.1 0.042 13.7 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_8 PF06259.12 GAX26414.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Palm_thioest PF02089.15 GAX26414.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF1749 PF08538.10 GAX26414.1 - 0.029 13.5 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) ATG_C PF09333.11 GAX26414.1 - 0.095 13.1 0.0 9.3 6.7 0.0 2.4 1 1 1 2 2 2 0 Autophagy-related protein C terminal domain FSH1 PF03959.13 GAX26414.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TAXi_N PF14543.6 GAX26415.1 - 6.8e-18 65.5 0.2 1.2e-17 64.7 0.2 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX26415.1 - 1e-12 48.2 0.0 1.6e-05 24.5 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX26415.1 - 0.01 15.7 0.0 4.4 7.1 0.0 2.8 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAX26415.1 - 0.1 13.2 0.1 14 6.4 0.0 3.2 4 0 0 4 4 4 0 Aspartyl protease DUF2358 PF10184.9 GAX26417.1 - 3.4e-14 53.1 0.0 4.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Thioredoxin_16 PF18569.1 GAX26417.1 - 0.01 15.9 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain dCMP_cyt_deam_1 PF00383.23 GAX26418.1 - 2.3e-47 159.0 0.1 6.1e-27 93.4 0.2 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX26418.1 - 4.6e-22 78.3 0.1 5.2e-13 48.9 0.1 2.3 2 0 0 2 2 2 2 MafB19-like deaminase APOBEC4_like PF18774.1 GAX26418.1 - 3e-06 27.2 0.0 0.003 17.5 0.0 2.3 2 0 0 2 2 2 2 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 GAX26418.1 - 0.00047 20.3 0.6 0.14 12.2 0.2 2.5 2 0 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 GAX26418.1 - 0.00051 20.2 0.9 0.25 11.4 0.4 2.4 2 0 0 2 2 2 2 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 GAX26418.1 - 0.0027 17.8 1.6 0.57 10.3 0.5 2.5 2 1 0 2 2 2 2 Bd3614-like deaminase APOBEC_N PF08210.11 GAX26418.1 - 0.0041 17.0 0.7 0.95 9.3 0.2 2.5 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC2 PF18772.1 GAX26418.1 - 0.0071 16.4 1.1 1.2 9.2 0.5 2.4 2 0 0 2 2 2 1 APOBEC2 APOBEC3 PF18771.1 GAX26418.1 - 0.089 12.9 0.3 2.2 8.4 0.2 2.3 2 0 0 2 2 2 0 APOBEC3 DAAD PF18752.1 GAX26418.1 - 0.09 12.6 0.2 1.3 8.8 0.1 2.5 2 1 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase APOBEC4 PF18775.1 GAX26418.1 - 0.15 12.2 1.2 18 5.6 0.3 2.8 2 1 0 2 2 2 0 APOBEC4 NAD2 PF18782.1 GAX26418.1 - 0.21 11.7 0.6 3.4 7.8 0.3 2.3 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 PRK PF00485.18 GAX26419.1 - 5.3e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAX26419.1 - 2.2e-08 34.7 0.0 6.3e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 GAX26419.1 - 1e-05 25.5 0.0 0.0051 16.7 0.0 2.4 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_17 PF13207.6 GAX26419.1 - 9.3e-05 22.9 0.1 0.038 14.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GAX26419.1 - 0.0001 22.0 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.6 GAX26419.1 - 0.00012 22.5 0.0 0.00022 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 GAX26419.1 - 0.0017 18.5 0.0 0.25 11.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain SKI PF01202.22 GAX26419.1 - 0.0018 18.4 0.1 0.66 10.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Zeta_toxin PF06414.12 GAX26419.1 - 0.0051 16.1 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 GAX26419.1 - 0.0055 16.4 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 GAX26419.1 - 0.0073 15.3 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 GAX26419.1 - 0.036 14.3 0.0 0.089 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GAX26419.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAX26419.1 - 0.11 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAX26419.1 - 0.11 12.4 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_tran PF00005.27 GAX26419.1 - 0.13 12.7 0.0 0.37 11.3 0.0 1.7 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 GAX26419.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ADK PF00406.22 GAX26419.1 - 0.19 11.8 0.4 2.9 8.0 0.1 2.5 2 1 1 3 3 3 0 Adenylate kinase NB-ARC PF00931.22 GAX26419.1 - 0.19 10.9 0.0 0.53 9.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain KTI12 PF08433.10 GAX26419.1 - 0.2 11.1 0.0 0.81 9.1 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 GAX26422.1 - 3.6e-48 163.6 0.0 1.7e-22 80.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX26422.1 - 6.2e-18 64.6 1.7 6.2e-18 64.6 1.7 4.6 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 GAX26422.1 - 1.6e-17 64.3 4.4 0.00033 20.6 0.0 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX26422.1 - 7.5e-11 41.9 6.3 0.013 14.9 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX26422.1 - 8.9e-09 35.0 0.0 0.00099 18.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAX26422.1 - 1.2e-07 32.2 0.1 0.011 16.2 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GAX26422.1 - 8.8e-07 29.6 23.1 0.0022 18.5 0.1 5.3 4 1 0 5 5 5 2 AAA domain AAA_28 PF13521.6 GAX26422.1 - 8.9e-06 26.0 0.1 0.029 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX26422.1 - 1.8e-05 25.0 0.2 0.32 11.3 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX26422.1 - 2.7e-05 24.7 0.7 0.038 14.5 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.6 GAX26422.1 - 3.4e-05 23.9 0.2 0.065 13.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 GAX26422.1 - 3.6e-05 24.2 0.5 0.055 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAX26422.1 - 8.3e-05 22.6 0.0 0.16 12.0 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX26422.1 - 0.0001 22.2 0.2 0.42 10.5 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 GAX26422.1 - 0.00012 22.3 0.3 0.37 11.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAX26422.1 - 0.00014 21.5 0.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 GAX26422.1 - 0.00015 21.5 0.0 0.72 9.5 0.1 3.2 3 0 0 3 3 2 2 AAA domain NB-ARC PF00931.22 GAX26422.1 - 0.00019 20.7 0.0 0.3 10.2 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 GAX26422.1 - 0.00019 21.8 0.2 0.55 10.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_30 PF13604.6 GAX26422.1 - 0.00072 19.3 0.1 1.7 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAX26422.1 - 0.00076 19.5 0.5 0.079 12.9 0.0 2.9 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAX26422.1 - 0.00094 19.2 0.0 0.6 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 GAX26422.1 - 0.0012 18.6 13.5 0.034 13.8 3.1 4.0 3 2 1 4 4 4 2 AAA ATPase domain ATP_bind_1 PF03029.17 GAX26422.1 - 0.0026 17.6 0.0 0.4 10.4 0.0 2.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_27 PF13514.6 GAX26422.1 - 0.0033 17.1 2.9 0.73 9.4 0.1 3.3 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 GAX26422.1 - 0.0037 17.0 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein NACHT PF05729.12 GAX26422.1 - 0.0039 17.1 0.1 1.8 8.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 GAX26422.1 - 0.0055 16.7 0.1 0.35 10.9 0.0 2.7 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 GAX26422.1 - 0.0081 15.9 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase PduV-EutP PF10662.9 GAX26422.1 - 0.019 14.7 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MukB PF04310.12 GAX26422.1 - 0.024 14.4 0.3 4.8 6.9 0.0 2.9 3 0 0 3 3 2 0 MukB N-terminal Rad17 PF03215.15 GAX26422.1 - 0.025 14.5 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Roc PF08477.13 GAX26422.1 - 0.034 14.3 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAX26422.1 - 0.041 13.1 0.1 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 GAX26422.1 - 0.059 12.8 0.5 0.29 10.6 0.0 2.4 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 GAX26422.1 - 0.069 12.5 0.1 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF5446 PF17522.2 GAX26422.1 - 0.071 13.3 5.8 0.13 12.5 2.8 2.9 3 0 0 3 3 2 0 Family of unknown function (DUF5446) cobW PF02492.19 GAX26422.1 - 0.072 12.7 0.1 4.3 6.9 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 GAX26422.1 - 0.073 12.6 0.0 11 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAX26422.1 - 0.084 12.8 0.9 5 7.0 0.2 2.9 2 1 1 3 3 2 0 NTPase DUF4829 PF16111.5 GAX26422.1 - 0.095 13.5 6.7 28 5.5 0.1 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4829) SRP54 PF00448.22 GAX26422.1 - 0.11 12.1 2.6 2.2 7.9 0.3 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 GAX26422.1 - 0.16 11.7 0.5 2.1 8.0 0.0 2.7 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SbcCD_C PF13558.6 GAX26422.1 - 0.19 12.0 3.6 3.3 8.0 0.0 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 GAX26422.1 - 0.68 10.0 5.4 34 4.4 0.0 3.9 4 0 0 4 4 4 0 Helicase HerA, central domain DUF3987 PF13148.6 GAX26422.1 - 1.2 8.0 6.9 12 4.8 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.10 GAX26422.1 - 3.4 7.7 7.4 4.6 7.3 2.0 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AAA_17 PF13207.6 GAX26422.1 - 3.5 8.1 9.3 3 8.3 0.2 3.9 3 1 0 3 3 3 0 AAA domain DFP PF04127.15 GAX26423.1 - 9.9e-16 58.1 0.0 1.2e-09 38.3 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Atx10homo_assoc PF09759.9 GAX26424.1 - 0.00075 19.5 0.0 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Glyco_transf_90 PF05686.12 GAX26425.1 - 1.9e-17 63.3 2.9 9.9e-16 57.6 1.3 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAX26425.1 - 0.0046 17.3 0.6 0.03 14.7 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Nup192 PF11894.8 GAX26426.1 - 3.4e-31 107.4 19.0 9.1e-21 72.9 0.3 4.1 4 0 0 4 4 4 4 Nuclear pore complex scaffold, nucleoporins 186/192/205 ComFB PF10719.9 GAX26426.1 - 0.055 13.6 0.0 0.75 9.9 0.0 2.6 2 0 0 2 2 2 0 Late competence development protein ComFB RasGAP_C PF03836.15 GAX26427.1 - 0.003 17.7 13.5 0.003 17.7 13.5 3.3 1 1 2 3 3 3 1 RasGAP C-terminus Peptidase_M22 PF00814.25 GAX26427.1 - 0.069 12.8 2.5 0.14 11.9 2.5 1.4 1 0 0 1 1 1 0 Glycoprotease family Fib_alpha PF08702.10 GAX26427.1 - 0.29 11.3 39.9 0.28 11.4 18.5 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TACC_C PF05010.14 GAX26427.1 - 0.9 9.3 53.8 0.13 12.0 36.5 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal UPF0242 PF06785.11 GAX26427.1 - 1.9 8.6 59.5 3.1 7.9 32.2 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 GAX26427.1 - 2.8 7.3 60.1 0.015 14.6 30.5 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 GAX26427.1 - 6.3 6.9 30.6 0.78 9.8 8.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 GAX26428.1 - 0.025 12.1 31.9 0.04 11.5 31.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1204 PF06721.11 GAX26428.1 - 1.7 8.0 18.8 0.27 10.6 5.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) DUF87 PF01935.17 GAX26428.1 - 2 8.5 13.3 0.4 10.7 4.4 2.7 1 1 1 3 3 3 0 Helicase HerA, central domain DUF724 PF05266.14 GAX26428.1 - 4.7 7.0 25.7 0.27 11.0 15.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GCN5L1 PF06320.13 GAX26428.1 - 6.5 6.9 20.6 8.3 6.6 5.9 3.0 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) MFS_1 PF07690.16 GAX26429.1 - 3e-15 56.0 18.8 3.7e-15 55.7 18.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 GAX26429.1 - 0.013 14.8 1.2 0.013 14.8 1.2 2.2 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DDRGK PF09756.9 GAX26430.1 - 1e-09 38.2 37.5 1.1e-08 34.9 37.5 2.5 1 1 0 1 1 1 1 DDRGK domain Caldesmon PF02029.15 GAX26430.1 - 0.0027 16.5 18.5 0.0031 16.3 18.5 1.0 1 0 0 1 1 1 1 Caldesmon Neur_chan_memb PF02932.16 GAX26430.1 - 0.08 13.0 5.8 0.11 12.5 5.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 GAX26430.1 - 0.9 9.8 12.5 1.2 9.3 12.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Borrelia_P83 PF05262.11 GAX26430.1 - 1.8 7.0 16.5 1.9 6.9 16.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 GAX26430.1 - 1.9 7.1 12.5 2.5 6.8 12.5 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 GAX26430.1 - 2.3 6.2 11.5 2.6 6.1 11.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 GAX26430.1 - 3.9 7.6 7.3 5.5 7.1 7.3 1.3 1 0 0 1 1 1 0 DDHD domain MDM10 PF12519.8 GAX26430.1 - 7.8 5.2 9.6 10 4.9 9.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Syja_N PF02383.18 GAX26431.1 - 0.038 13.3 0.1 2.1 7.6 0.0 2.1 1 1 1 2 2 2 0 SacI homology domain ENT PF03735.14 GAX26433.1 - 0.07 13.2 0.1 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 ENT domain AA_permease_2 PF13520.6 GAX26434.1 - 6.3e-38 130.7 37.4 6.3e-38 130.7 37.4 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAX26434.1 - 2.3e-16 59.5 40.6 4.6e-16 58.5 40.6 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GAX26434.1 - 1.2e-13 50.9 3.8 1.2e-13 50.9 3.8 3.6 4 0 0 4 4 4 1 C-terminus of AA_permease TBCC PF07986.12 GAX26435.1 - 5.3e-25 87.5 0.3 9.6e-25 86.7 0.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 GAX26435.1 - 9.5e-06 25.3 0.5 1.8e-05 24.4 0.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal zf-RVT PF13966.6 GAX26437.1 - 0.00046 20.9 1.0 0.00046 20.9 1.0 2.8 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase Aldedh PF00171.22 GAX26438.1 - 1.2e-75 254.8 0.0 1.5e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GATase_2 PF00310.21 GAX26439.1 - 5.8e-168 559.0 0.0 8.7e-168 558.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GAX26439.1 - 6.2e-156 519.2 0.8 1.6e-152 507.9 0.1 2.3 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GAX26439.1 - 7.7e-110 366.8 0.0 2.3e-108 361.9 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GAX26439.1 - 6.1e-81 270.6 2.9 1.1e-80 269.7 2.9 1.4 1 0 0 1 1 1 1 GXGXG motif Herpes_UL56 PF04534.12 GAX26439.1 - 0.67 9.4 4.2 1.9 7.9 4.2 1.7 1 0 0 1 1 1 0 Herpesvirus UL56 protein FMN_dh PF01070.18 GAX26439.1 - 1.9 7.5 5.9 0.88 8.5 1.3 2.4 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Ank_2 PF12796.7 GAX26440.1 - 1.3e-10 41.7 0.7 2.2e-06 28.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX26440.1 - 2.9e-09 37.3 3.4 0.00017 22.1 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX26440.1 - 4.3e-06 26.7 0.1 0.59 10.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAX26440.1 - 6e-05 23.2 0.6 0.069 13.5 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Zn_Tnp_IS1595 PF12760.7 GAX26440.1 - 0.0014 18.6 2.6 0.0047 16.9 2.6 2.0 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Ank PF00023.30 GAX26440.1 - 0.0022 18.4 0.0 4.2 8.0 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeat Cytochrome_C7 PF14522.6 GAX26440.1 - 0.15 12.1 3.1 0.37 10.8 0.6 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Fea1 PF07692.11 GAX26442.1 - 5.7e-06 25.6 0.9 0.03 13.4 0.2 2.6 2 1 1 3 3 3 2 Low iron-inducible periplasmic protein tRNA_anti-codon PF01336.25 GAX26443.1 - 0.071 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain UBM PF14377.6 GAX26443.1 - 0.092 12.2 0.2 0.25 10.9 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin binding region SPC25 PF06703.11 GAX26444.1 - 1.9e-32 112.3 0.0 2.6e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) HypA PF01155.19 GAX26445.1 - 0.00079 19.4 0.1 0.001 19.1 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin PF00301.20 GAX26445.1 - 0.0099 15.9 6.7 0.2 11.7 6.7 2.3 1 1 0 1 1 1 1 Rubredoxin TF_Zn_Ribbon PF08271.12 GAX26445.1 - 0.01 15.4 0.7 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding ADK_lid PF05191.14 GAX26445.1 - 0.15 12.1 3.7 0.34 10.9 3.7 1.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid OrfB_Zn_ribbon PF07282.11 GAX26445.1 - 0.37 10.7 2.7 1.1 9.2 0.2 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2 PF00096.26 GAX26445.1 - 1.5 9.4 4.5 5.2 7.7 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type HA PF03457.14 GAX26447.1 - 3.6e-33 113.7 10.0 4.8e-11 42.8 0.4 4.1 3 1 0 3 3 3 3 Helicase associated domain Spore_coat_CotO PF14153.6 GAX26447.1 - 0.57 10.1 9.9 2 8.3 9.9 2.0 1 0 0 1 1 1 0 Spore coat protein CotO DAO PF01266.24 GAX26448.1 - 1.8e-53 182.3 0.1 2.2e-53 182.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX26448.1 - 2.4e-07 30.9 0.1 6e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX26448.1 - 1.3e-05 24.6 0.2 2.8e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX26448.1 - 5.8e-05 23.6 0.2 0.00014 22.3 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX26448.1 - 6.1e-05 22.4 0.5 0.00011 21.5 0.2 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAX26448.1 - 6.2e-05 21.9 0.8 0.00034 19.5 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAX26448.1 - 0.00025 20.4 0.2 0.00042 19.7 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX26448.1 - 0.00062 19.0 1.9 0.0013 17.9 1.8 1.6 1 1 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAX26448.1 - 0.00089 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAX26448.1 - 0.0011 19.2 0.1 0.002 18.3 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.19 GAX26448.1 - 0.0014 17.9 0.3 0.0021 17.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAX26448.1 - 0.0019 17.6 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 GAX26448.1 - 0.0025 17.7 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GAX26448.1 - 0.0029 17.3 0.3 0.0055 16.4 0.3 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 GAX26448.1 - 0.0073 15.4 0.3 0.059 12.4 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 GAX26448.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAX26448.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 GAX26448.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 GAX26448.1 - 0.023 15.3 0.4 0.045 14.3 0.4 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GAX26448.1 - 0.031 14.3 0.2 0.058 13.5 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX26448.1 - 0.042 14.1 0.2 0.13 12.5 0.2 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAX26448.1 - 0.047 13.2 0.6 0.091 12.2 0.1 1.6 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_2 PF03446.15 GAX26448.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 GAX26448.1 - 0.17 10.9 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GDI PF00996.18 GAX26448.1 - 0.19 10.2 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor ThiF PF00899.21 GAX26448.1 - 0.2 11.0 0.1 0.51 9.7 0.1 1.6 1 0 0 1 1 1 0 ThiF family zf-UBP PF02148.19 GAX26449.1 - 3.1e-18 65.9 5.8 3.1e-18 65.9 5.8 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 GAX26449.1 - 0.017 14.9 4.1 0.027 14.2 3.6 1.7 1 1 0 1 1 1 0 Variant UBP zinc finger PEP-utilisers_N PF05524.13 GAX26449.1 - 0.034 14.3 11.6 0.071 13.3 11.5 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal MbeD_MobD PF04899.12 GAX26449.1 - 2.1 8.5 11.4 0.093 12.9 2.5 2.5 1 1 1 2 2 2 0 MbeD/MobD like Spc7 PF08317.11 GAX26449.1 - 3.2 6.6 17.0 4.8 6.0 17.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fungal_TACC PF12709.7 GAX26449.1 - 3.2 8.3 6.1 0.56 10.7 0.5 2.6 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Iron_permease PF04120.12 GAX26449.1 - 4.3 7.1 6.8 0.48 10.2 1.3 2.2 2 1 1 3 3 3 0 Low affinity iron permease BCD PF15461.6 GAX26450.1 - 0.024 14.2 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Peptidase_C1 PF00112.23 GAX26451.1 - 8.4e-67 225.4 0.1 1e-66 225.1 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX26451.1 - 1.8e-12 47.5 0.4 2.8e-12 46.9 0.4 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAX26451.1 - 0.00037 19.4 0.0 0.18 10.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF1894 PF08979.11 GAX26451.1 - 0.018 15.4 0.0 0.052 13.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) Aminotran_1_2 PF00155.21 GAX26452.1 - 1.8e-44 152.4 0.0 2.2e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAX26452.1 - 0.011 15.1 0.0 0.051 12.9 0.0 2.0 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family UMP1 PF05348.11 GAX26453.1 - 2.9e-16 59.7 0.0 3.4e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MFS_1 PF07690.16 GAX26454.1 - 3.1e-23 82.3 35.7 1.1e-22 80.4 34.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAX26454.1 - 0.09 11.0 4.7 0.031 12.6 1.4 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RabGAP-TBC PF00566.18 GAX26455.1 - 4.7e-52 176.8 0.6 6.8e-52 176.2 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAM220 PF15487.6 GAX26455.1 - 0.19 11.3 1.9 0.33 10.6 1.9 1.3 1 0 0 1 1 1 0 FAM220 family PBP1_TM PF14812.6 GAX26455.1 - 0.23 11.8 4.1 7.4 7.0 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_22 PF03901.17 GAX26456.1 - 7.5e-62 209.9 25.9 9.6e-62 209.5 25.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 GAX26457.1 - 9.1e-46 156.3 0.0 1.8e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26457.1 - 2.4e-21 76.2 0.0 1.5e-20 73.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX26457.1 - 1.4e-08 34.0 0.2 1.9e-08 33.6 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAX26457.1 - 9.6e-06 25.1 0.6 1.6e-05 24.4 0.6 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAX26457.1 - 0.00065 19.4 0.0 0.043 13.4 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAX26457.1 - 0.0076 16.2 0.1 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX26457.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Trypsin_2 PF13365.6 GAX26458.1 - 3.4e-14 54.0 0.0 9.6e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain COR PF16095.5 GAX26458.1 - 2e-06 27.8 0.0 4.5e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 GAX26458.1 - 0.00051 20.2 0.0 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Trypsin PF00089.26 GAX26458.1 - 0.02 14.7 0.1 2.1 8.1 0.0 3.4 3 0 0 3 3 3 0 Trypsin PTR2 PF00854.21 GAX26459.1 - 6.4e-85 285.4 3.9 8.7e-85 284.9 3.9 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 GAX26459.1 - 1.7e-08 33.8 19.5 3.8e-05 22.8 0.3 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2301 PF10063.9 GAX26459.1 - 0.089 13.2 1.9 0.32 11.4 1.9 1.9 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) PDZ PF00595.24 GAX26460.1 - 0.0025 18.1 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX26460.1 - 0.03 14.2 0.1 0.97 9.3 0.0 2.6 3 0 0 3 3 3 0 PDZ domain PDZ_2 PF13180.6 GAX26460.1 - 0.056 13.8 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 PDZ domain mit_SMPDase PF14724.6 GAX26461.1 - 3.6e-07 28.6 0.5 0.036 12.0 0.9 3.1 2 1 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase PAP_central PF04928.17 GAX26462.1 - 0.023 13.7 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Poly(A) polymerase central domain CaM_binding PF07839.11 GAX26462.1 - 0.25 12.1 3.7 0.34 11.7 0.4 2.7 3 0 0 3 3 3 0 Plant calmodulin-binding domain Trs65 PF12735.7 GAX26463.1 - 1.4e-12 47.7 0.0 3.8e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Gryzun-like PF12742.7 GAX26463.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking B_lectin PF01453.24 GAX26464.1 - 0.041 14.4 0.6 1.8 9.1 0.1 2.6 2 0 0 2 2 2 0 D-mannose binding lectin CwfJ_C_1 PF04677.15 GAX26465.1 - 8.7e-22 77.3 0.1 1.8e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 GAX26465.1 - 5.1e-09 35.8 0.0 0.00034 20.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 GAX26465.1 - 9.3e-07 29.7 0.0 2.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 IF4E PF01652.18 GAX26466.1 - 1.8e-50 170.9 0.0 2.4e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SMC_N PF02463.19 GAX26467.1 - 5.5e-48 163.3 62.5 8.3e-47 159.4 62.5 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAX26467.1 - 3e-31 108.1 0.2 1.8e-29 102.4 0.1 3.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 GAX26467.1 - 4.5e-14 52.9 0.0 4.5e-14 52.9 0.0 4.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 GAX26467.1 - 3.3e-13 50.1 0.1 6.2e-08 32.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAX26467.1 - 4.5e-07 29.5 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 GAX26467.1 - 0.002 17.1 20.1 0.002 17.1 20.1 7.2 3 2 4 7 7 7 4 Spc7 kinetochore protein AAA_23 PF13476.6 GAX26467.1 - 7.4 7.0 131.4 1.1 9.8 67.6 7.3 3 2 0 3 3 3 0 AAA domain Sec7 PF01369.20 GAX26468.1 - 2.7e-54 183.7 0.0 1.4e-53 181.3 0.0 2.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 GAX26468.1 - 0.0034 17.3 2.9 0.015 15.2 0.0 3.3 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal IBN_N PF03810.19 GAX26468.1 - 0.063 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Importin-beta N-terminal domain STN1_2 PF09170.10 GAX26468.1 - 0.12 12.6 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 PhyH PF05721.13 GAX26469.1 - 5.7e-14 52.9 0.1 1e-13 52.0 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAX26469.1 - 0.0005 19.0 0.3 0.74 8.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Myosin_head PF00063.21 GAX26470.1 - 1.6e-220 733.9 0.0 2.2e-220 733.4 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Ank PF00023.30 GAX26470.1 - 4.4e-21 74.3 15.0 4.6e-05 23.7 0.1 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.7 GAX26470.1 - 8.9e-20 71.1 4.3 2.1e-08 34.7 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX26470.1 - 7.2e-19 67.6 6.1 7.7e-06 26.1 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX26470.1 - 3.1e-16 59.5 7.5 0.025 15.2 0.0 6.5 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX26470.1 - 1e-10 40.9 9.2 0.47 11.2 0.0 7.3 7 0 0 7 7 6 3 Ankyrin repeat IQ PF00612.27 GAX26470.1 - 3.2e-05 23.3 29.2 0.031 14.0 0.4 6.4 6 0 0 6 6 6 2 IQ calmodulin-binding motif FYVE PF01363.21 GAX26470.1 - 6.4e-05 23.0 13.7 0.00014 21.9 13.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_16 PF13191.6 GAX26470.1 - 0.0019 18.6 4.4 0.04 14.3 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain GAS PF13851.6 GAX26470.1 - 0.0053 16.1 10.2 0.019 14.4 10.2 1.9 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HOOK PF05622.12 GAX26470.1 - 0.011 13.9 9.6 0.018 13.2 9.6 1.2 1 0 0 1 1 1 0 HOOK protein Sigma54_activat PF00158.26 GAX26470.1 - 0.024 14.3 0.0 0.083 12.6 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 GAX26470.1 - 0.06 13.6 1.4 0.29 11.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain CorA PF01544.18 GAX26470.1 - 0.2 10.9 5.5 0.51 9.6 5.5 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 GAX26470.1 - 0.24 11.5 8.1 0.54 10.3 8.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 GAX26470.1 - 0.31 9.6 5.3 0.6 8.7 5.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 GAX26470.1 - 0.32 11.2 17.6 0.74 10.1 7.2 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran PF00005.27 GAX26470.1 - 0.32 11.5 1.2 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RPW8 PF05659.11 GAX26470.1 - 0.97 9.1 5.9 7.8 6.2 5.6 2.5 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF87 PF01935.17 GAX26470.1 - 2 8.4 4.3 13 5.8 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain Fez1 PF06818.15 GAX26470.1 - 2.6 8.5 17.2 1.3 9.4 14.0 2.2 2 0 0 2 2 1 0 Fez1 IBR PF01485.21 GAX26470.1 - 3.8 7.8 12.4 1.8 8.8 6.3 3.3 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain HIP1_clath_bdg PF16515.5 GAX26470.1 - 4.2 8.1 17.7 0.92 10.2 8.3 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATPase PF06745.13 GAX26470.1 - 5.2 6.3 5.0 15 4.9 0.0 2.6 2 0 0 2 2 2 0 KaiC APG6_N PF17675.1 GAX26470.1 - 6 7.4 15.8 34 5.0 15.7 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Med9 PF07544.13 GAX26470.1 - 6.8 6.9 9.7 3.1 8.0 4.8 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Helo_like_N PF17111.5 GAX26470.1 - 8.9 5.6 9.2 0.16 11.4 1.5 2.0 3 0 0 3 3 2 0 Fungal N-terminal domain of STAND proteins Choline_transpo PF04515.12 GAX26472.1 - 6.6e-68 229.3 22.5 6.6e-68 229.3 22.5 2.9 1 1 2 3 3 3 2 Plasma-membrane choline transporter DUF4999 PF16390.5 GAX26472.1 - 0.12 12.6 0.3 2.1 8.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function SF-assemblin PF06705.11 GAX26473.1 - 0.26 10.6 7.5 0.21 10.9 4.3 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin MutS_III PF05192.18 GAX26473.1 - 4.5 7.4 6.4 9.1 6.4 3.7 2.6 1 1 1 2 2 2 0 MutS domain III Med4 PF10018.9 GAX26474.1 - 3.1e-06 27.0 7.0 7.9e-06 25.7 7.0 1.7 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CPP1-like PF11833.8 GAX26474.1 - 3.2 7.3 5.4 5.7 6.5 5.4 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Amidinotransf PF02274.17 GAX26475.1 - 2.3e-11 43.4 0.0 1.1e-10 41.1 0.0 1.9 1 1 1 2 2 2 1 Amidinotransferase COX15-CtaA PF02628.15 GAX26476.1 - 5.3e-97 324.8 8.9 6.1e-97 324.6 8.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Macoilin PF09726.9 GAX26478.1 - 2.3 6.7 5.6 4.7 5.6 5.6 1.4 1 0 0 1 1 1 0 Macoilin family Cation_efflux PF01545.21 GAX26479.1 - 1.6e-41 142.3 7.8 2.4e-41 141.6 7.8 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAX26479.1 - 9.9e-10 38.4 1.3 0.0014 18.7 0.1 2.8 2 0 0 2 2 2 2 Dimerisation domain of Zinc Transporter Peptidase_S10 PF00450.22 GAX26480.1 - 3e-83 280.6 0.0 4.8e-83 279.9 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase N_methyl PF07963.12 GAX26480.1 - 0.093 12.3 3.3 0.17 11.5 3.3 1.3 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif Trypsin PF00089.26 GAX26481.1 - 1.1e-35 123.4 0.0 1.4e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin Ureide_permease PF07168.11 GAX26481.1 - 0.063 12.0 0.1 3.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Ureide permease DsrH PF04077.12 GAX26482.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 DsrH like protein TraE PF05309.11 GAX26482.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 TraE protein TB PF00683.17 GAX26482.1 - 3.5 7.5 5.4 24 4.8 0.4 2.5 2 0 0 2 2 2 0 TB domain Peptidase_S8 PF00082.22 GAX26484.1 - 3.6e-37 128.3 5.6 2.8e-36 125.3 5.6 1.9 1 1 0 1 1 1 1 Subtilase family CBM49 PF09478.10 GAX26484.1 - 0.069 13.5 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 Inhibitor_I9 PF05922.16 GAX26484.1 - 0.097 13.4 0.7 0.24 12.1 0.7 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I9 Aldose_epim PF01263.20 GAX26485.1 - 5.2e-51 173.7 0.2 5.9e-51 173.6 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase STAT_alpha PF01017.20 GAX26487.1 - 0.0072 16.2 0.3 0.018 14.9 0.3 1.7 1 0 0 1 1 1 1 STAT protein, all-alpha domain YqfQ PF14181.6 GAX26487.1 - 3.5 7.8 5.9 0.43 10.8 0.8 2.1 2 0 0 2 2 2 0 YqfQ-like protein RE_Alw26IDE PF09665.10 GAX26488.1 - 0.094 11.9 0.3 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) ThiF PF00899.21 GAX26490.1 - 2e-64 217.3 0.0 2.9e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 GAX26490.1 - 1.2e-20 73.4 0.1 2.4e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 E2 binding domain Ecm33 PF12454.8 GAX26490.1 - 0.07 13.3 1.3 0.13 12.4 1.3 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Shikimate_DH PF01488.20 GAX26490.1 - 0.15 12.1 0.1 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Plasmodium_HRP PF05403.11 GAX26491.1 - 2e-13 50.6 38.3 1.9e-06 27.9 7.8 3.4 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) Pkinase PF00069.25 GAX26496.1 - 1.2e-34 119.9 0.0 4.7e-34 118.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26496.1 - 3.1e-32 111.9 0.0 4.4e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX26496.1 - 0.0013 18.7 0.1 0.0042 17.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX26496.1 - 0.0092 14.8 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Thump_like PF18096.1 GAX26496.1 - 0.034 14.1 0.3 0.45 10.5 0.1 2.6 3 0 0 3 3 3 0 THUMP domain-like bZIP_1 PF00170.21 GAX26498.1 - 2.6e-08 33.9 6.1 2.6e-08 33.9 6.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX26498.1 - 1e-07 31.9 9.2 1e-07 31.9 9.2 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAX26498.1 - 0.0058 17.1 2.7 0.0058 17.1 2.7 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor MIP-T3_C PF17749.1 GAX26498.1 - 0.006 16.6 1.0 0.012 15.6 1.0 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region SR-25 PF10500.9 GAX26498.1 - 0.018 14.6 7.8 0.027 14.1 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IFT57 PF10498.9 GAX26498.1 - 0.029 13.4 3.0 0.075 12.0 3.0 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 GAX26498.1 - 0.092 12.1 0.4 0.1 12.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 GAX26498.1 - 0.22 11.5 5.4 0.94 9.5 0.5 2.5 2 1 0 2 2 2 0 FlxA-like protein DUF2203 PF09969.9 GAX26498.1 - 0.63 10.8 3.0 0.25 12.1 0.7 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Macoilin PF09726.9 GAX26498.1 - 8.6 4.8 10.9 24 3.3 10.9 1.6 1 1 0 1 1 1 0 Macoilin family bZIP_1 PF00170.21 GAX26499.1 - 7.9e-07 29.1 11.1 7.9e-07 29.1 11.1 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX26499.1 - 9.3e-05 22.4 11.7 9.3e-05 22.4 11.7 2.2 2 0 0 2 2 2 1 Basic region leucine zipper Tup_N PF08581.10 GAX26499.1 - 0.0061 16.8 1.7 0.0061 16.8 1.7 2.1 2 0 0 2 2 2 1 Tup N-terminal AKNA PF12443.8 GAX26499.1 - 0.23 12.1 5.7 0.81 10.4 0.4 2.6 2 1 0 2 2 2 0 AT-hook-containing transcription factor Cep57_MT_bd PF06657.13 GAX26499.1 - 0.36 11.3 7.6 0.15 12.5 0.9 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 RasGAP_C PF03836.15 GAX26499.1 - 0.45 10.7 7.6 0.091 12.9 2.3 2.0 1 1 1 2 2 2 0 RasGAP C-terminus bZIP_Maf PF03131.17 GAX26499.1 - 0.72 10.4 14.6 0.047 14.2 7.5 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor IFT57 PF10498.9 GAX26499.1 - 0.72 8.8 12.5 7 5.5 12.5 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 YlqD PF11068.8 GAX26499.1 - 1.1 9.7 8.2 0.22 11.9 3.4 1.9 2 0 0 2 2 2 0 YlqD protein MRPL52 PF18699.1 GAX26499.1 - 1.2 9.4 13.8 0.096 12.9 4.2 2.3 2 0 0 2 2 2 0 Mitoribosomal protein mL52 XhlA PF10779.9 GAX26499.1 - 1.5 9.1 8.0 0.28 11.4 2.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF4407 PF14362.6 GAX26499.1 - 2.7 7.3 11.7 4.9 6.4 11.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) POX PF07526.11 GAX26499.1 - 3.8 8.1 7.1 6.3 7.4 7.1 1.4 1 1 0 1 1 1 0 Associated with HOX Tho2 PF11262.8 GAX26499.1 - 4.8 6.3 13.1 0.1 11.8 3.5 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 SlyX PF04102.12 GAX26499.1 - 7 7.4 8.2 24 5.6 0.3 3.0 2 1 1 3 3 3 0 SlyX zf-CCCH PF00642.24 GAX26501.1 - 4.7e-10 39.1 7.0 1.1e-05 25.2 1.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAX26501.1 - 3.8e-07 29.9 9.3 0.00029 20.8 2.0 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAX26501.1 - 7.4e-07 28.8 8.0 0.0007 19.3 1.9 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 GAX26501.1 - 0.0042 17.8 4.6 0.13 13.0 0.8 2.6 1 1 1 2 2 2 2 Torus domain GED PF02212.18 GAX26501.1 - 0.22 11.7 2.3 0.45 10.7 2.3 1.4 1 0 0 1 1 1 0 Dynamin GTPase effector domain zf-CCCH_2 PF14608.6 GAX26501.1 - 0.3 11.6 9.9 0.056 13.9 2.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 GAX26501.1 - 6.5 6.8 6.0 36 4.4 0.1 3.4 4 0 0 4 4 4 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Ank_2 PF12796.7 GAX26503.1 - 1.4e-15 57.7 0.4 8.2e-08 32.7 0.1 2.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX26503.1 - 2.2e-10 40.9 0.3 7.2e-06 26.5 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX26503.1 - 7.5e-07 29.3 0.1 4.1e-06 27.0 0.0 2.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX26503.1 - 1.6e-05 24.9 0.0 0.0033 17.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX26503.1 - 0.00021 21.6 0.0 1 9.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Vpu PF00558.19 GAX26503.1 - 0.22 11.3 0.7 0.43 10.4 0.7 1.4 1 0 0 1 1 1 0 Vpu protein APH PF01636.23 GAX26504.1 - 4.7e-18 66.0 2.3 4.7e-18 66.0 2.3 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX26504.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase adh_short_C2 PF13561.6 GAX26505.1 - 9e-53 179.2 0.1 1.1e-52 179.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX26505.1 - 3.9e-37 127.6 0.1 4.6e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX26505.1 - 6.2e-16 58.8 0.6 8.4e-16 58.4 0.6 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX26505.1 - 0.045 12.9 0.0 0.063 12.4 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein tRNA-synt_2 PF00152.20 GAX26506.1 - 1.2e-85 287.3 0.0 1.5e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX26506.1 - 1.2e-10 41.3 0.1 2.2e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX26506.1 - 0.0012 18.4 0.3 0.63 9.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF758 PF05527.11 GAX26506.1 - 0.048 13.6 0.5 0.084 12.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Na_Pi_cotrans PF02690.15 GAX26507.1 - 1.4e-33 116.0 30.3 2.5e-18 66.5 7.6 2.6 2 0 0 2 2 2 2 Na+/Pi-cotransporter MLANA PF14991.6 GAX26507.1 - 0.0024 18.1 0.1 0.0073 16.6 0.1 1.8 1 0 0 1 1 1 1 Protein melan-A CRCB PF02537.15 GAX26508.1 - 8.8e-25 86.9 10.2 2e-15 56.9 0.3 2.5 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Methyltransf_16 PF10294.9 GAX26509.1 - 2.9e-18 66.2 0.0 5.5e-18 65.3 0.0 1.4 1 1 1 2 2 2 1 Lysine methyltransferase Methyltransf_31 PF13847.6 GAX26509.1 - 4.6e-10 39.5 0.0 8.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX26509.1 - 1.9e-08 34.3 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX26509.1 - 6.8e-06 26.7 0.0 1.4e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX26509.1 - 9.5e-06 25.3 0.0 2.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX26509.1 - 2.2e-05 25.1 0.0 4.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX26509.1 - 2.8e-05 24.7 0.0 6.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GAX26509.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) ER_lumen_recept PF00810.18 GAX26510.1 - 1.3e-47 162.3 12.2 1.3e-47 162.3 12.2 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor AAA-ATPase_like PF09820.9 GAX26511.1 - 0.014 14.8 0.2 0.019 14.4 0.2 1.4 1 0 0 1 1 1 0 Predicted AAA-ATPase AHSP PF09236.10 GAX26511.1 - 0.024 15.0 2.7 0.18 12.3 1.1 2.5 2 1 0 2 2 2 0 Alpha-haemoglobin stabilising protein DUF4976 PF16347.5 GAX26511.1 - 3.5 7.9 5.6 0.63 10.3 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) FliJ PF02050.16 GAX26512.1 - 9.1 6.5 12.2 1 9.6 3.1 3.0 3 1 0 3 3 3 0 Flagellar FliJ protein MgtC PF02308.16 GAX26513.1 - 1.1e-33 116.1 4.2 1.1e-33 116.1 4.2 1.9 2 0 0 2 2 2 1 MgtC family GT87 PF09594.10 GAX26513.1 - 0.065 12.9 3.1 0.09 12.5 0.2 2.2 2 1 0 2 2 2 0 Glycosyltransferase family 87 DUF521 PF04412.13 GAX26514.1 - 3.4e-109 365.2 0.0 4.8e-109 364.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 GAX26514.1 - 2.1e-29 101.1 0.0 4.1e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase X swivel domain DAGK_cat PF00781.24 GAX26515.1 - 0.047 13.3 0.1 0.062 12.9 0.1 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain WD40 PF00400.32 GAX26516.1 - 2.8e-07 31.1 8.8 0.0045 17.8 0.5 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX26516.1 - 0.0005 20.3 0.0 0.014 15.7 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Itfg2 PF15907.5 GAX26516.1 - 0.094 11.7 1.2 0.43 9.6 0.1 2.3 2 1 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF493 PF04359.14 GAX26517.1 - 8.6e-10 39.1 0.0 1.3e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF493) DUF3212 PF11486.8 GAX26517.1 - 0.042 13.9 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) PYST-C1 PF09690.10 GAX26519.1 - 0.0039 16.9 1.8 0.012 15.3 1.8 1.8 1 0 0 1 1 1 1 Plasmodium yoelii subtelomeric region (PYST-C1) Topoisom_bac PF01131.20 GAX26520.1 - 2.6e-104 349.5 0.0 3.3e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 GAX26520.1 - 1.7e-16 60.3 0.0 3.5e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-HC3 PF16827.5 GAX26520.1 - 0.12 12.6 2.1 19 5.6 0.0 2.9 2 0 0 2 2 2 0 zinc-finger zf-Di19 PF05605.12 GAX26520.1 - 1.9 8.9 8.7 6.8 7.1 0.1 4.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Rotamase PF00639.21 GAX26521.1 - 3.8e-22 79.1 0.0 4.4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX26521.1 - 6.7e-18 65.3 0.0 7.5e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAX26521.1 - 3.4e-07 31.1 0.0 3.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 GAX26521.1 - 0.056 14.1 0.0 0.078 13.7 0.0 1.2 1 0 0 1 1 1 0 X8 domain Amino_oxidase PF01593.24 GAX26522.1 - 9.5e-20 71.3 0.0 2.3e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX26522.1 - 1.7e-12 47.4 0.1 3.3e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAX26522.1 - 1.8e-05 24.8 0.1 0.14 12.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 GAX26522.1 - 0.00011 22.0 1.1 0.00022 21.0 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAX26522.1 - 0.00014 21.3 1.4 0.0011 18.3 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAX26522.1 - 0.00035 19.9 0.0 0.0069 15.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX26522.1 - 0.0015 17.3 0.4 0.0038 16.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GAX26522.1 - 0.019 14.2 0.2 0.03 13.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 GAX26522.1 - 0.025 13.7 0.3 0.037 13.1 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 GAX26522.1 - 0.045 12.5 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 GAX26522.1 - 0.057 12.5 0.1 0.097 11.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 GAX26522.1 - 0.066 12.4 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GAX26522.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX26522.1 - 0.13 12.9 1.3 0.17 12.5 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX26523.1 - 1.1e-10 41.3 0.0 7e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX26523.1 - 1.5e-06 28.4 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAX26523.1 - 3.7e-06 26.5 0.0 4.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAX26523.1 - 1.2e-05 24.7 0.0 0.00051 19.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX26523.1 - 0.00019 21.1 0.0 0.00054 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAX26523.1 - 0.0018 17.6 0.2 0.0056 16.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAX26523.1 - 0.0018 17.0 0.0 0.0062 15.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 GAX26523.1 - 0.0023 18.0 0.0 1.1 9.2 0.0 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAX26523.1 - 0.0044 17.5 0.4 0.01 16.4 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX26523.1 - 0.0082 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAX26523.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAX26523.1 - 0.063 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.21 GAX26523.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family O-FucT PF10250.9 GAX26524.1 - 1.6e-09 37.9 0.0 2.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro81C PF17652.1 GAX26526.1 - 1.1e-64 218.9 0.0 3.9e-64 217.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAX26526.1 - 2.4e-24 86.1 2.1 4.2e-24 85.3 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Coprogen_oxidas PF01218.18 GAX26527.1 - 2.3e-131 436.9 0.0 2.7e-131 436.7 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SSXT PF05030.12 GAX26529.1 - 0.0001 21.8 3.6 0.00011 21.8 0.6 2.5 3 0 0 3 3 3 1 SSXT protein (N-terminal region) Vps26 PF03643.15 GAX26530.1 - 1.2e-83 280.4 0.0 2e-82 276.3 0.0 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAX26530.1 - 0.012 15.6 0.1 30 4.7 0.0 3.4 2 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain His_Phos_1 PF00300.22 GAX26531.1 - 2.5e-13 50.2 0.0 1.3e-12 47.8 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.32 GAX26532.1 - 2.9e-35 119.7 16.5 2.8e-10 40.6 0.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX26532.1 - 1.1e-12 48.0 0.2 3.6e-05 24.0 0.0 5.5 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 GAX26532.1 - 6.1e-07 29.7 0.8 0.00053 20.2 0.0 3.3 3 1 1 4 4 4 2 WD40 associated region in TFIID subunit, NTD2 domain eIF2A PF08662.11 GAX26532.1 - 0.00034 20.5 0.0 0.00075 19.4 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAX26532.1 - 0.015 14.6 0.0 0.035 13.4 0.0 1.6 1 1 1 2 2 2 0 WD40-like domain RAB3GAP2_N PF14655.6 GAX26532.1 - 0.026 13.8 1.7 0.41 9.8 0.0 3.0 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 GAX26532.1 - 0.067 11.7 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain RRM_1 PF00076.22 GAX26533.1 - 3.1e-13 49.3 0.0 6.4e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 GAX26533.1 - 3.2e-11 43.8 0.1 5.7e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Inhibitor_I9 PF05922.16 GAX26535.1 - 0.09 13.5 1.2 0.14 12.8 1.2 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 Guanylate_cyc PF00211.20 GAX26536.1 - 7.3e-22 77.9 0.1 6.9e-10 38.8 0.1 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 GAX26536.1 - 6.4e-08 33.2 0.0 1.7e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX26536.1 - 0.0013 19.0 0.0 0.011 16.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX26536.1 - 0.0091 16.3 0.0 0.056 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF4777 PF16007.5 GAX26536.1 - 0.0098 16.1 0.2 0.034 14.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4777) TPR_MalT PF17874.1 GAX26536.1 - 0.014 14.8 0.1 1.8 7.9 0.1 3.4 2 1 1 4 4 4 0 MalT-like TPR region AAA_29 PF13555.6 GAX26536.1 - 0.093 12.5 0.0 0.33 10.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_7 PF13176.6 GAX26536.1 - 0.14 12.2 0.2 1e+02 3.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AlkA_N PF06029.11 GAX26537.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AlkA N-terminal domain DBINO PF13892.6 GAX26537.1 - 3.7 7.9 5.9 8.9 6.7 0.5 3.0 3 0 0 3 3 3 0 DNA-binding domain Phage_30_3 PF08010.11 GAX26538.1 - 0.16 11.7 1.3 0.67 9.7 1.3 1.9 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 LRR_6 PF13516.6 GAX26539.1 - 2.6e-26 89.4 36.3 0.00027 20.7 0.0 15.6 16 0 0 16 16 16 7 Leucine Rich repeat LRR_8 PF13855.6 GAX26539.1 - 4.2e-19 68.1 14.3 1.4e-06 27.9 0.4 8.4 7 1 1 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 GAX26539.1 - 2.7e-18 65.8 25.8 0.0034 17.8 0.4 10.9 7 2 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAX26539.1 - 4.4e-05 23.1 0.3 0.76 9.3 0.1 4.0 1 1 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 GAX26539.1 - 0.00039 20.6 31.9 9 7.3 0.6 11.5 14 1 0 14 14 14 4 Leucine Rich Repeat ICMT PF04140.14 GAX26540.1 - 5.5e-22 78.0 2.9 7.8e-22 77.5 0.7 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAX26540.1 - 2e-09 37.8 0.8 2e-09 37.8 0.8 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase GBP PF02263.19 GAX26541.1 - 8.4e-48 162.9 2.1 1.6e-47 161.9 2.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.6 GAX26541.1 - 0.056 13.8 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF4303 PF14136.6 GAX26541.1 - 0.086 12.6 2.5 0.19 11.5 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) RAC_head PF16717.5 GAX26541.1 - 2.3 9.2 5.7 0.29 12.2 0.7 2.1 2 0 0 2 2 2 0 Ribosome-associated complex head domain Acyl_transf_1 PF00698.21 GAX26542.1 - 4.9e-23 82.1 0.4 6.6e-23 81.7 0.4 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 GAX26542.1 - 0.0023 17.7 0.3 0.028 14.2 0.3 2.2 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis O-FucT PF10250.9 GAX26545.1 - 0.043 13.5 0.0 0.06 13.0 0.0 1.4 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase PepSY PF03413.19 GAX26545.1 - 0.1 13.2 0.3 0.18 12.4 0.3 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Sarcolipin PF05366.11 GAX26545.1 - 8.4 6.2 8.3 0.39 10.4 2.9 1.6 2 0 0 2 2 2 0 Sarcolipin YEATS PF03366.16 GAX26546.1 - 4.6e-26 90.6 0.1 1.1e-25 89.4 0.0 1.7 2 0 0 2 2 2 1 YEATS family Dicty_REP PF05086.12 GAX26546.1 - 0.24 9.3 6.0 0.28 9.1 6.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2839 PF10999.8 GAX26547.1 - 0.039 14.3 0.0 0.062 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) DUF4089 PF13318.6 GAX26547.1 - 0.1 13.1 0.5 9.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) Folliculin PF11704.8 GAX26549.1 - 0.85 9.5 3.9 1.9 8.3 3.9 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport VCBS PF13517.6 GAX26551.1 - 9.3e-05 22.9 0.0 0.14 12.8 0.0 3.7 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAX26551.1 - 0.0015 18.6 3.2 0.33 11.1 1.1 3.2 3 0 0 3 3 3 1 FG-GAP repeat PQQ_2 PF13360.6 GAX26551.1 - 0.0015 18.1 0.1 0.3 10.6 0.0 2.8 3 0 0 3 3 3 1 PQQ-like domain SUIM_assoc PF16619.5 GAX26551.1 - 0.062 13.4 8.8 0.019 15.0 3.0 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 GAX26551.1 - 0.31 11.0 15.8 0.029 14.4 7.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 GAX26551.1 - 0.47 10.8 5.8 4.9 7.5 0.4 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like PPP4R2 PF09184.11 GAX26552.1 - 2.2e-11 43.9 0.1 2.2e-11 43.9 0.1 3.3 3 0 0 3 3 3 1 PPP4R2 ECR1_N PF14382.6 GAX26553.1 - 3.9e-07 29.8 0.1 1.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 GAX26553.1 - 5.4e-05 23.8 0.1 0.085 13.5 0.0 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 AAA PF00004.29 GAX26554.1 - 2.7e-12 47.3 0.0 1.1e-11 45.3 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX26554.1 - 1.5e-07 31.5 0.0 4.8e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX26554.1 - 1e-06 29.0 0.1 7.2e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX26554.1 - 4.8e-06 27.1 0.1 5e-05 23.7 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GAX26554.1 - 1.5e-05 24.8 0.5 0.00011 22.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAX26554.1 - 0.00032 20.7 0.0 0.00085 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX26554.1 - 0.00087 19.8 0.0 0.0025 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX26554.1 - 0.0011 18.1 1.1 0.0032 16.6 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 GAX26554.1 - 0.0012 18.8 0.2 0.015 15.2 0.2 2.7 1 1 0 1 1 1 1 NACHT domain Rad17 PF03215.15 GAX26554.1 - 0.0021 18.0 0.5 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 GAX26554.1 - 0.0035 17.1 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAX26554.1 - 0.0047 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 GAX26554.1 - 0.0059 16.8 0.0 0.0059 16.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 GAX26554.1 - 0.006 16.8 0.5 0.035 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX26554.1 - 0.0088 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAX26554.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 GAX26554.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 GAX26554.1 - 0.03 13.9 0.0 0.086 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX26554.1 - 0.033 14.7 0.0 1.2 9.7 0.0 3.1 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 GAX26554.1 - 0.034 14.5 2.5 0.047 14.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAX26554.1 - 0.054 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 NTPase ATPase PF06745.13 GAX26554.1 - 0.063 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 GAX26554.1 - 0.076 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 GAX26554.1 - 0.08 12.7 0.1 0.08 12.7 0.1 3.4 3 1 0 3 3 2 0 AAA domain NB-ARC PF00931.22 GAX26554.1 - 0.089 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.6 GAX26554.1 - 0.12 12.8 0.0 2.9 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 GAX26555.1 - 2.5e-54 184.3 0.0 1.1e-28 100.0 0.0 3.2 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX26555.1 - 1.2e-13 51.3 0.0 5.2e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 GAX26555.1 - 1.9e-09 38.3 0.0 9.9e-09 35.9 0.0 2.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_3 PF13920.6 GAX26555.1 - 0.00034 20.4 9.6 0.00034 20.4 9.6 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.6 GAX26555.1 - 0.23 11.4 6.1 0.98 9.4 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4 PF00097.25 GAX26555.1 - 9.4 6.2 24.8 0.04 13.8 12.0 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Bcr-Abl_Oligo PF09036.10 GAX26556.1 - 0.087 12.8 0.2 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain PDZ_6 PF17820.1 GAX26556.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 PDZ domain Antimicrobial24 PF16049.5 GAX26556.1 - 5.5 7.1 8.2 12 6.0 8.2 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide Ras PF00071.22 GAX26557.1 - 1e-59 200.8 0.0 1.2e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX26557.1 - 5.9e-33 113.6 0.0 1e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX26557.1 - 1.3e-11 44.3 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX26557.1 - 3e-05 24.1 0.0 0.00026 21.0 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX26557.1 - 0.0015 18.4 0.1 0.32 10.9 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAX26557.1 - 0.0025 17.2 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX26557.1 - 0.008 15.7 0.0 0.053 13.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAX26557.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAX26557.1 - 0.039 13.7 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 GAX26557.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Peptidase_M16 PF00675.20 GAX26558.1 - 8.9e-20 71.2 0.0 2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX26558.1 - 0.021 14.8 0.0 0.076 13.0 0.0 1.9 2 0 0 2 2 2 0 Peptidase M16 inactive domain Peptidase_M44 PF03410.13 GAX26558.1 - 0.092 11.3 0.0 0.25 9.9 0.0 1.6 2 0 0 2 2 2 0 Metallopeptidase from vaccinia pox SASA PF03629.18 GAX26559.1 - 2.4e-13 50.3 0.0 3.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase DUF2109 PF09882.9 GAX26560.1 - 0.025 14.6 0.6 0.025 14.6 0.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Tetraspanin PF00335.20 GAX26560.1 - 8 6.1 7.8 8.3 6.0 2.1 2.2 2 0 0 2 2 2 0 Tetraspanin family HA2 PF04408.23 GAX26562.1 - 2.6e-26 92.0 0.8 7.4e-26 90.6 0.1 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX26562.1 - 2.4e-23 82.3 0.0 6e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX26562.1 - 1.1e-11 45.1 0.0 3.4e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX26562.1 - 2.4e-06 27.4 0.0 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAX26562.1 - 0.00035 20.9 0.3 0.0018 18.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX26562.1 - 0.0022 18.3 0.2 0.0073 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAX26562.1 - 0.0028 16.7 0.0 0.0095 15.0 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein HTH_ParB PF17762.1 GAX26562.1 - 0.011 15.5 0.5 0.096 12.5 0.0 2.6 2 0 0 2 2 2 0 HTH domain found in ParB protein AAA_30 PF13604.6 GAX26562.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAX26562.1 - 0.025 13.8 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) S1 PF00575.23 GAX26562.1 - 0.037 14.4 0.2 0.083 13.2 0.2 1.6 1 0 0 1 1 1 0 S1 RNA binding domain AAA_14 PF13173.6 GAX26562.1 - 0.041 13.9 0.3 0.93 9.5 0.3 2.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 GAX26562.1 - 0.048 13.1 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 GAX26562.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAX26562.1 - 0.17 12.4 0.7 0.53 10.8 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 GAX26562.1 - 0.2 12.0 0.5 1 9.7 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Shikimate_DH PF01488.20 GAX26564.1 - 0.13 12.3 1.4 6.7 6.8 0.3 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PPR_2 PF13041.6 GAX26565.1 - 0.0003 20.9 0.1 0.34 11.1 0.0 5.0 6 0 0 6 6 6 1 PPR repeat family PPR_3 PF13812.6 GAX26565.1 - 0.00043 20.3 0.3 1.5 8.9 0.0 4.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Clathrin PF00637.20 GAX26565.1 - 0.0017 18.2 1.4 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS PPR PF01535.20 GAX26565.1 - 0.021 15.1 2.5 11 6.5 0.0 5.2 4 1 0 4 4 4 0 PPR repeat ELYS PF13934.6 GAX26565.1 - 0.026 14.5 13.3 0.091 12.7 1.1 4.1 3 1 0 4 4 4 0 Nuclear pore complex assembly PPR_long PF17177.4 GAX26565.1 - 0.11 11.9 2.0 8.6 5.7 0.0 3.6 5 0 0 5 5 5 0 Pentacotripeptide-repeat region of PRORP FlbT PF07378.11 GAX26565.1 - 1.3 9.1 3.9 23 5.1 0.1 3.6 4 0 0 4 4 4 0 Flagellar protein FlbT Glu_cyclase_2 PF05096.12 GAX26566.1 - 5.6e-68 229.1 0.3 7e-68 228.8 0.3 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase SdiA-regulated PF06977.11 GAX26566.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 SdiA-regulated Cupin_3 PF05899.12 GAX26567.1 - 0.0025 17.5 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GAX26567.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Pirin_C PF05726.13 GAX26567.1 - 0.052 13.9 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 Pirin C-terminal cupin domain DNA_pol_B PF00136.21 GAX26568.1 - 2.9e-71 240.5 0.0 4.7e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 GAX26568.1 - 0.00022 21.6 14.2 0.00064 20.1 14.2 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.19 GAX26568.1 - 0.00026 20.3 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain E2F_TDP PF02319.20 GAX26568.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain HemY_N PF07219.13 GAX26569.1 - 0.0052 17.0 0.1 0.0052 17.0 0.1 2.8 2 1 1 3 3 3 1 HemY protein N-terminus LRIF1 PF15741.5 GAX26569.1 - 0.071 11.6 15.1 0.079 11.5 15.1 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Phage_P2_GpU PF06995.11 GAX26569.1 - 0.092 12.4 0.5 0.16 11.6 0.5 1.3 1 0 0 1 1 1 0 Phage P2 GpU TFIIA PF03153.13 GAX26569.1 - 1.7 8.5 21.0 2.3 8.1 21.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paramyxo_ncap PF00973.19 GAX26569.1 - 3.2 6.6 9.3 5.3 5.8 9.3 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mre11_DNA_bind PF04152.14 GAX26570.1 - 1.3e-37 129.7 0.2 1.3e-37 129.7 0.2 2.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 GAX26570.1 - 2.3e-12 47.8 0.3 4e-12 47.1 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX26570.1 - 0.00019 21.7 0.0 0.0049 17.1 0.0 3.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GDP_Man_Dehyd PF16363.5 GAX26571.1 - 1.4e-68 231.7 0.0 1.7e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX26571.1 - 1.1e-53 182.2 0.0 1.5e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAX26571.1 - 1e-20 74.1 0.0 5.4e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAX26571.1 - 1.8e-19 69.8 0.0 2.6e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAX26571.1 - 1.2e-17 64.0 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX26571.1 - 2.7e-17 62.8 0.0 3.3e-16 59.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAX26571.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 GAX26571.1 - 0.032 13.7 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase tRNA-synt_2 PF00152.20 GAX26572.1 - 3e-71 240.1 0.0 4.2e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX26572.1 - 5.8e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX26572.1 - 0.00072 19.1 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF2514 PF10721.9 GAX26572.1 - 0.0063 16.6 1.1 0.014 15.4 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) SIMPL PF04402.14 GAX26572.1 - 0.037 14.5 0.6 0.075 13.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) tRNA_anti_2 PF13742.6 GAX26572.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ribosomal_L36e PF01158.18 GAX26572.1 - 0.21 11.9 1.8 0.42 10.9 1.8 1.4 1 0 0 1 1 1 0 Ribosomal protein L36e RCC1 PF00415.18 GAX26573.1 - 2.1e-60 201.1 14.7 2.3e-10 40.9 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX26573.1 - 9.8e-27 92.2 35.4 3.1e-08 33.2 1.1 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 GAX26573.1 - 0.074 13.5 0.9 6.8 7.2 0.0 3.4 3 0 0 3 3 3 0 SUKH-3 immunity protein Homeobox_KN PF05920.11 GAX26574.1 - 4.1e-15 55.4 0.1 8.5e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAX26574.1 - 3.4e-06 26.8 0.2 8e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain IBN_N PF03810.19 GAX26574.1 - 0.19 11.7 0.8 0.36 10.8 0.1 1.9 2 0 0 2 2 2 0 Importin-beta N-terminal domain Peptidase_M8 PF01457.16 GAX26575.1 - 4.3e-08 32.3 0.0 5.2e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin zf-met PF12874.7 GAX26576.1 - 2.1e-05 24.7 3.3 2.1e-05 24.7 3.3 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAX26576.1 - 0.00013 22.2 4.2 0.00027 21.1 4.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Rad33 PF08730.10 GAX26576.1 - 0.0081 16.2 0.2 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 Rad33 zf-U1 PF06220.12 GAX26576.1 - 0.011 15.5 3.2 0.022 14.5 3.2 1.4 1 0 0 1 1 1 0 U1 zinc finger DUF2514 PF10721.9 GAX26576.1 - 0.016 15.3 5.7 0.016 15.3 5.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Imm5 PF14423.6 GAX26576.1 - 0.047 13.9 1.9 0.1 12.8 1.9 1.6 1 1 0 1 1 1 0 Immunity protein Imm5 MCU PF04678.13 GAX26576.1 - 2.4 8.2 9.0 0.11 12.5 2.6 2.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter LMBR1 PF04791.16 GAX26576.1 - 9.7 5.0 7.2 11 4.8 7.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_12 PF13424.6 GAX26577.1 - 1.5e-09 38.0 0.1 3.5e-05 24.0 0.0 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26577.1 - 2.5e-07 30.3 0.6 0.52 10.6 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX26577.1 - 3.2e-05 24.4 0.8 4.4 8.4 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX26577.1 - 8.4e-05 22.2 0.9 2.1 8.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat MAS20 PF02064.15 GAX26577.1 - 0.002 18.2 1.7 0.0036 17.4 0.3 2.0 2 0 0 2 2 2 1 MAS20 protein import receptor TPR_8 PF13181.6 GAX26577.1 - 0.005 16.9 1.3 0.32 11.3 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Sec39 PF08314.11 GAX26577.1 - 0.054 12.0 0.3 0.25 9.7 0.0 1.8 2 0 0 2 2 2 0 Secretory pathway protein Sec39 YL1_C PF08265.11 GAX26578.1 - 4.5e-10 39.1 0.0 7.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 GAX26578.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger Fe-ADH PF00465.19 GAX26579.1 - 1.5e-112 376.1 0.5 2.4e-112 375.4 0.1 1.6 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 GAX26579.1 - 8.4e-27 93.8 3.6 8.5e-26 90.5 3.6 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 GAX26579.1 - 5.6e-20 72.1 2.0 1e-09 38.5 0.5 3.2 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Ribonuc_red_lgN PF00317.21 GAX26579.1 - 0.041 13.9 0.4 0.31 11.1 0.0 2.5 3 0 0 3 3 3 0 Ribonucleotide reductase, all-alpha domain MFS_1 PF07690.16 GAX26580.1 - 2.7e-22 79.2 18.2 2.7e-22 79.2 18.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAX26580.1 - 0.00078 18.1 3.0 0.0013 17.4 3.0 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 GAX26580.1 - 0.00081 18.4 13.7 0.33 9.8 13.7 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 GAX26580.1 - 0.00091 17.7 10.0 0.0022 16.4 10.0 1.6 1 1 0 1 1 1 1 Transmembrane secretion effector BT1 PF03092.16 GAX26580.1 - 0.0085 14.4 0.1 0.014 13.6 0.1 1.3 1 0 0 1 1 1 1 BT1 family XPG_I PF00867.18 GAX26581.1 - 5.5e-19 68.3 0.0 1.4e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region Chromo_2 PF18704.1 GAX26581.1 - 2.4e-13 50.1 0.0 4.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 XPG_N PF00752.17 GAX26581.1 - 3.5e-08 33.8 0.0 1.2e-07 32.2 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain Kelch_4 PF13418.6 GAX26582.1 - 6.1e-30 103.0 1.7 4.8e-07 29.7 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 GAX26582.1 - 3e-25 87.9 4.4 1.6e-06 28.3 0.1 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX26582.1 - 3.9e-25 87.2 3.0 2.3e-06 27.7 0.1 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 GAX26582.1 - 2.4e-24 84.9 0.3 0.00045 20.1 0.2 6.5 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 GAX26582.1 - 2.1e-21 75.8 6.0 2.1e-21 75.8 6.0 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 GAX26582.1 - 3.3e-17 61.8 0.1 6.1e-05 22.5 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAX26582.1 - 3.7e-12 45.7 6.1 0.039 13.9 0.6 7.6 7 1 0 7 7 7 3 Kelch motif DUF2894 PF11445.8 GAX26583.1 - 0.21 12.1 7.4 0.23 11.9 6.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) WDCP PF15390.6 GAX26583.1 - 0.31 9.4 7.2 0.38 9.1 7.2 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF1664 PF07889.12 GAX26583.1 - 1.2 9.2 5.5 0.61 10.1 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 GAX26583.1 - 3.8 7.9 16.6 1.7 9.0 7.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SAE2 PF08573.10 GAX26583.1 - 4.4 8.5 7.8 15 6.8 7.8 2.0 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus FUSC PF04632.12 GAX26583.1 - 5.2 5.5 6.1 6.2 5.2 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNA_pol_N PF01194.17 GAX26584.1 - 2.4e-33 114.2 0.3 2.8e-33 114.0 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 GAX26584.1 - 0.037 14.3 0.5 0.068 13.4 0.5 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DTC PF18102.1 GAX26585.1 - 5.3e-35 120.5 0.0 9.4e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_2 PF13639.6 GAX26585.1 - 4e-09 36.7 3.5 7.9e-09 35.7 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX26585.1 - 1.8e-07 30.9 3.7 3.5e-07 29.9 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX26585.1 - 1.1e-06 28.4 3.1 2.1e-06 27.5 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX26585.1 - 1.4e-06 28.2 1.5 2.7e-06 27.3 0.9 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAX26585.1 - 6.2e-05 22.6 2.1 0.00013 21.6 2.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAX26585.1 - 0.00056 20.1 2.9 0.0011 19.2 2.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAX26585.1 - 0.0012 18.7 2.9 0.0021 17.9 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX26585.1 - 0.0019 18.2 0.9 0.01 15.9 1.4 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAX26585.1 - 0.0036 17.2 4.3 0.0065 16.4 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAX26585.1 - 0.0056 16.8 1.4 0.018 15.2 1.3 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 GAX26585.1 - 0.02 14.8 4.1 0.078 12.9 3.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 GAX26585.1 - 0.11 12.3 2.4 0.24 11.2 2.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 GAX26585.1 - 0.12 12.6 2.3 0.25 11.5 2.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX26585.1 - 0.47 10.1 6.0 1.7 8.3 5.1 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 GAX26585.1 - 1.2 9.1 3.5 2.4 8.1 3.5 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 GAX26585.1 - 2.7 7.9 5.3 26 4.8 5.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TPM_phosphatase PF04536.14 GAX26586.1 - 2.1e-10 40.9 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 TPM domain Golgin_A5 PF09787.9 GAX26587.1 - 3.1e-09 36.7 10.4 3.1e-09 36.7 10.4 4.2 2 1 2 4 4 4 1 Golgin subfamily A member 5 Sas6_CC PF18594.1 GAX26587.1 - 0.12 12.2 6.0 11 5.9 0.1 3.5 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain RRM_1 PF00076.22 GAX26588.1 - 2.9e-11 43.0 0.0 1.3e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ketoacyl-synt PF00109.26 GAX26590.1 - 5.5e-47 160.5 2.6 5.5e-47 160.5 2.6 2.4 2 2 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAX26590.1 - 4.4e-29 100.9 1.5 4.9e-29 100.8 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAX26590.1 - 0.0027 17.1 0.5 0.007 15.8 0.3 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Nop52 PF05997.12 GAX26591.1 - 1.2e-44 152.7 1.1 9.8e-27 94.1 0.2 3.3 3 0 0 3 3 3 2 Nucleolar protein,Nop52 SDA1 PF05285.12 GAX26591.1 - 0.68 9.3 59.5 0.19 11.1 19.9 2.3 2 0 0 2 2 2 0 SDA1 RRM_1 PF00076.22 GAX26592.1 - 9.8e-16 57.3 0.0 2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.6 GAX26592.1 - 0.0025 17.6 3.3 0.021 14.7 3.3 2.1 1 1 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 GAX26592.1 - 0.079 13.1 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif RCC1 PF00415.18 GAX26594.1 - 5.8e-33 113.3 4.1 9.2e-09 35.8 0.4 6.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX26594.1 - 9.3e-12 44.4 19.1 0.031 14.1 0.0 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DEAD PF00270.29 GAX26595.1 - 2e-15 57.0 0.0 5e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX26595.1 - 4.9e-14 52.6 0.0 8.3e-12 45.4 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-GRF PF06839.12 GAX26595.1 - 2.4e-10 40.3 6.3 5.9e-10 39.1 6.3 1.7 1 0 0 1 1 1 1 GRF zinc finger ResIII PF04851.15 GAX26595.1 - 1.1e-07 32.1 0.0 3.3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SAP PF02037.27 GAX26595.1 - 4.1e-07 29.6 0.0 9.2e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 SAP domain Methyltransf_15 PF09445.10 GAX26596.1 - 5.6e-23 81.3 0.0 1.3e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 GAX26596.1 - 0.00046 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX26596.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AviRa PF11599.8 GAX26596.1 - 0.036 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Met_10 PF02475.16 GAX26596.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein tRNA_U5-meth_tr PF05958.11 GAX26596.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NMU PF02070.15 GAX26597.1 - 0.063 13.2 0.5 0.23 11.4 0.5 2.0 1 0 0 1 1 1 0 Neuromedin U SPC12 PF06645.13 GAX26598.1 - 3.2e-29 100.8 2.2 3.5e-29 100.7 2.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Mntp PF02659.15 GAX26598.1 - 0.01 15.6 1.4 0.012 15.4 1.4 1.1 1 0 0 1 1 1 0 Putative manganese efflux pump DUF1453 PF07301.11 GAX26598.1 - 0.024 14.6 0.5 0.031 14.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) DUF3087 PF11286.8 GAX26598.1 - 0.18 11.3 0.1 0.19 11.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) EamA PF00892.20 GAX26599.1 - 7.8e-21 74.7 33.1 9.4e-11 42.0 10.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family zf-RING_2 PF13639.6 GAX26600.1 - 4.5e-11 42.9 5.7 8.4e-11 42.0 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX26600.1 - 1.9e-07 30.8 5.8 3.7e-07 29.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX26600.1 - 4.1e-07 29.9 3.9 6.9e-07 29.1 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAX26600.1 - 4.5e-07 30.1 3.8 1e-06 28.9 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX26600.1 - 4.8e-07 29.7 0.7 1e-06 28.7 0.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAX26600.1 - 5.4e-07 29.3 2.4 5.4e-07 29.3 2.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX26600.1 - 1.9e-06 27.6 5.8 3.7e-06 26.7 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX26600.1 - 4.2e-06 26.5 4.2 7.4e-06 25.7 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX26600.1 - 9.8e-06 25.3 4.2 2e-05 24.4 4.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAX26600.1 - 0.00027 20.9 0.9 0.0017 18.3 1.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX26600.1 - 0.0082 15.7 4.9 0.029 14.0 4.5 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DBD_HTH PF18430.1 GAX26600.1 - 0.033 13.9 0.2 0.1 12.4 0.2 1.8 1 0 0 1 1 1 0 Putative DNA-binding domain FANCL_C PF11793.8 GAX26600.1 - 0.099 12.8 5.0 0.32 11.2 5.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 GAX26600.1 - 0.1 12.7 6.0 0.22 11.7 6.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 GAX26600.1 - 0.11 12.6 0.9 0.28 11.3 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger ER_lumen_recept PF00810.18 GAX26600.1 - 0.23 12.3 11.1 0.46 11.3 11.1 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor zf-RING_4 PF14570.6 GAX26600.1 - 0.67 9.8 4.9 1.7 8.5 4.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sdh5 PF03937.16 GAX26601.1 - 1.4e-20 73.0 0.0 1.4e-20 73.0 0.0 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Thioredoxin PF00085.20 GAX26602.1 - 1.1e-14 54.3 0.0 2.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 GAX26602.1 - 0.0012 19.0 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX26602.1 - 0.002 18.4 0.1 0.01 16.2 0.1 2.1 1 1 2 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 GAX26602.1 - 0.0021 17.5 0.2 0.0053 16.2 0.0 1.6 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAX26602.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Evr1_Alr PF04777.13 GAX26603.1 - 4.4e-14 52.8 0.4 1.1e-13 51.5 0.4 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 GAX26603.1 - 1.4e-13 50.7 0.0 3.9e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 GAX26603.1 - 0.078 13.2 0.1 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 GAX26603.1 - 0.08 13.3 0.3 1.1 9.6 0.0 3.0 2 1 1 3 3 3 0 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX26603.1 - 0.11 12.9 0.0 0.51 10.8 0.0 2.1 1 0 0 1 1 1 0 Thioredoxin-like domain PhyH PF05721.13 GAX26604.1 - 2.6e-26 93.2 0.1 3.9e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AIRC PF00731.20 GAX26605.1 - 1.4e-65 219.4 5.1 1.6e-65 219.2 2.6 2.3 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 GAX26605.1 - 1.5e-45 154.9 0.0 2.8e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 GAX26605.1 - 7.9e-19 67.1 0.1 1.7e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 GAX26605.1 - 0.029 13.9 0.0 0.088 12.3 0.0 1.8 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus Jag_N PF14804.6 GAX26605.1 - 0.12 12.8 1.5 0.5 10.8 0.2 2.7 2 0 0 2 2 2 0 Jag N-terminus Ni_hydr_CYTB PF01292.20 GAX26606.1 - 2.3e-15 56.7 6.2 3.1e-15 56.2 6.2 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Presenilin PF01080.17 GAX26607.1 - 0.0044 15.8 6.5 0.0044 15.8 6.5 2.0 2 0 0 2 2 2 1 Presenilin SLC12 PF03522.15 GAX26607.1 - 3.5 6.5 10.4 5.1 6.0 10.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 GAX26607.1 - 5.1 7.5 7.1 9.9 6.6 7.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Guanylate_cyc PF00211.20 GAX26608.1 - 1.4e-15 57.4 0.2 1.2e-07 31.6 0.0 2.8 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 GAX26608.1 - 2e-12 47.8 0.7 3e-07 31.0 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAX26608.1 - 0.00029 21.1 0.0 0.0012 19.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAX26608.1 - 0.0012 18.1 0.1 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 GAX26608.1 - 0.0016 18.4 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.17 GAX26608.1 - 0.0078 16.2 0.0 0.34 11.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat PhoH PF02562.16 GAX26608.1 - 0.012 15.1 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 GAX26608.1 - 0.013 14.8 0.0 0.03 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 GAX26608.1 - 0.034 14.7 1.7 0.076 13.5 0.5 2.2 2 0 0 2 2 2 0 ABC transporter TPR_12 PF13424.6 GAX26608.1 - 0.04 14.2 1.1 1.9 8.8 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_7 PF12775.7 GAX26608.1 - 0.046 13.2 0.1 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region OKR_DC_1_N PF03709.15 GAX26608.1 - 0.064 13.5 0.1 1.4 9.2 0.0 3.0 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_19 PF13245.6 GAX26608.1 - 0.086 13.2 0.0 3.3 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAX26608.1 - 0.091 12.8 0.2 0.58 10.3 0.1 2.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase N6_Mtase PF02384.16 GAX26609.1 - 8.1e-07 28.6 0.0 1.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase MTS PF05175.14 GAX26609.1 - 1.8e-05 24.4 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX26609.1 - 9.4e-05 23.0 0.0 0.00027 21.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX26609.1 - 0.0002 21.2 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GAX26609.1 - 0.00024 20.9 0.0 0.0016 18.2 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 GAX26609.1 - 0.0056 16.5 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX26609.1 - 0.0068 17.0 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 GAX26609.1 - 0.0071 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) EcoRI_methylase PF13651.6 GAX26609.1 - 0.01 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Methyltransf_12 PF08242.12 GAX26609.1 - 0.052 14.3 0.0 0.13 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 GAX26609.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Metallophos PF00149.28 GAX26610.1 - 2e-10 41.5 0.1 3.7e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAX26610.1 - 1.3e-06 28.8 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 GAX26610.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Methyltransf_16 PF10294.9 GAX26611.1 - 7.3e-29 100.7 0.1 8.7e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAX26611.1 - 4.9e-06 26.2 0.1 6.9e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX26611.1 - 0.00016 22.3 0.0 0.00031 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX26611.1 - 0.00068 19.5 0.0 0.00091 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX26611.1 - 0.00092 19.1 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX26611.1 - 0.0017 17.8 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 GAX26611.1 - 0.0024 17.0 0.1 0.003 16.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 GAX26611.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 GAX26611.1 - 0.13 12.9 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DDE_Tnp_4 PF13359.6 GAX26613.1 - 3.9e-28 98.1 0.0 5.9e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAX26613.1 - 2.8e-06 27.1 0.9 3e-05 23.7 0.1 2.4 2 1 0 2 2 2 1 Transposase DDE domain Plant_tran PF04827.14 GAX26613.1 - 0.00038 20.1 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Peptidase_M20 PF01546.28 GAX26615.1 - 1.1e-33 116.7 0.0 1.7e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAX26615.1 - 2.2e-07 30.8 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAX26615.1 - 1.3e-05 25.0 0.0 7.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 PseudoU_synth_2 PF00849.22 GAX26616.1 - 5.4e-25 88.3 0.0 1.8e-24 86.6 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase Trp_Tyr_perm PF03222.13 GAX26617.1 - 3.4e-70 237.1 24.5 6e-70 236.3 24.5 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 GAX26617.1 - 1.4e-05 24.0 24.4 0.00025 19.9 24.4 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Lipase_GDSL PF00657.22 GAX26618.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Spt4 PF06093.13 GAX26619.1 - 2.4e-28 98.0 0.1 3.2e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-MYND PF01753.18 GAX26620.1 - 8.7e-08 32.1 14.0 1.6e-07 31.3 14.0 1.5 1 0 0 1 1 1 1 MYND finger TPR_19 PF14559.6 GAX26620.1 - 3e-06 27.6 0.3 1.3e-05 25.6 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX26620.1 - 0.00032 20.9 0.5 20 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX26620.1 - 0.00045 20.4 1.1 0.018 15.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAX26620.1 - 0.002 17.9 0.2 1.3 9.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX26620.1 - 0.003 17.5 0.3 0.59 10.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26620.1 - 0.0035 17.3 0.6 0.18 12.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX26620.1 - 0.0042 16.9 5.3 0.0094 15.7 0.0 4.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX26620.1 - 0.0058 16.8 0.1 0.15 12.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX26620.1 - 0.032 14.8 0.1 0.28 11.9 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX26620.1 - 0.049 14.3 0.2 6 7.6 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX26620.1 - 0.051 14.4 0.5 10 7.2 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX26620.1 - 0.18 11.5 0.4 18 5.1 0.0 3.5 3 1 1 4 4 4 0 TPR repeat LD_cluster2 PF18163.1 GAX26621.1 - 0.038 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster2 Porphyrn_cat_1 PF18206.1 GAX26621.1 - 0.053 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Porphyranase catalytic subdomain 1 Rhomboid PF01694.22 GAX26622.1 - 5.6e-17 62.1 12.2 5.6e-17 62.1 12.2 2.2 2 1 0 2 2 2 1 Rhomboid family MnhB PF04039.13 GAX26622.1 - 0.0039 17.5 1.4 0.23 11.8 0.1 3.2 2 1 0 3 3 3 1 Domain related to MnhB subunit of Na+/H+ antiporter PAS_9 PF13426.7 GAX26623.1 - 4e-09 36.7 0.0 8.4e-09 35.6 0.0 1.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 GAX26623.1 - 1.9e-07 31.0 0.0 4.2e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 GAX26623.1 - 0.00046 20.4 0.0 0.00099 19.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 GAX26623.1 - 0.0067 16.4 0.0 0.044 13.8 0.0 2.1 1 1 1 2 2 2 1 PAS domain Cyclin_N PF00134.23 GAX26624.1 - 1.6e-08 34.3 0.0 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX26624.1 - 0.0067 16.5 0.8 0.013 15.6 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain CxC4 PF18717.1 GAX26624.1 - 0.032 14.1 0.1 0.083 12.7 0.1 1.7 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases WW PF00397.26 GAX26625.1 - 7.5e-13 48.3 2.0 2.1e-12 46.9 2.0 1.9 1 0 0 1 1 1 1 WW domain Hydrolase_3 PF08282.12 GAX26626.1 - 0.26 11.0 0.0 1.7 8.3 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RVT_2 PF07727.14 GAX26628.1 - 7.6e-40 137.1 0.0 1.3e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX26628.1 - 2.8e-06 27.5 0.0 9.3e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 GAX26628.1 - 0.002 18.0 0.1 0.0052 16.6 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF202 PF02656.15 GAX26629.1 - 4.8e-17 62.2 0.4 9.6e-17 61.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) PsbU PF06514.11 GAX26630.1 - 1.6e-20 72.9 0.0 2.3e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 GAX26630.1 - 0.0017 18.6 0.0 0.003 17.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif CytB6-F_Fe-S PF08802.10 GAX26630.1 - 0.018 15.0 0.2 0.058 13.4 0.0 1.9 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit WD40 PF00400.32 GAX26631.1 - 6.1e-35 118.7 19.1 1.8e-05 25.4 1.6 10.1 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX26631.1 - 3.6e-16 59.2 0.6 0.0023 18.2 0.0 7.1 3 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX26631.1 - 0.0047 16.8 0.0 0.074 12.9 0.0 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAX26631.1 - 0.0091 14.6 0.0 0.39 9.2 0.0 2.4 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 GAX26631.1 - 0.03 13.6 0.7 9.2 5.5 0.2 3.2 3 1 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 GAX26631.1 - 0.083 11.8 0.3 1 8.3 0.1 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 GAX26631.1 - 0.12 12.1 0.2 4.3 7.0 0.0 2.9 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.6 GAX26631.1 - 8.5 7.0 12.3 15 6.2 0.4 5.0 4 1 0 4 4 4 0 PQQ-like domain UPF0126 PF03458.13 GAX26632.1 - 5.3e-38 128.8 14.0 9.1e-22 76.7 5.9 2.2 2 0 0 2 2 2 2 UPF0126 domain DUF998 PF06197.13 GAX26632.1 - 1.1 8.8 9.7 8.1 6.0 5.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Fusion_gly PF00523.18 GAX26635.1 - 0.063 11.5 0.1 0.16 10.2 0.1 1.6 2 0 0 2 2 2 0 Fusion glycoprotein F0 Cut8 PF08559.10 GAX26636.1 - 0.065 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein AFG1_ATPase PF03969.16 GAX26637.1 - 1.7e-61 208.2 1.5 2.6e-58 197.7 0.2 2.9 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 GAX26637.1 - 1.4e-05 25.6 0.2 0.0002 21.8 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAX26637.1 - 0.00033 21.0 0.0 0.0013 19.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 GAX26637.1 - 0.0021 18.0 0.1 0.012 15.5 0.0 2.2 2 1 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 GAX26637.1 - 0.025 14.6 0.2 0.35 10.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 GAX26637.1 - 0.16 11.7 0.4 3.5 7.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein VEFS-Box PF09733.9 GAX26639.1 - 2.2e-15 56.7 0.0 3.8e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DNA_RNApol_7kD PF03604.13 GAX26639.1 - 0.076 12.7 0.3 0.076 12.7 0.3 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit AMP-binding PF00501.28 GAX26640.1 - 5.2e-85 285.6 0.0 6.5e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme zf-RING_2 PF13639.6 GAX26642.1 - 3e-12 46.7 3.8 3e-12 46.7 3.8 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX26642.1 - 2.4e-11 43.3 3.7 5.1e-11 42.2 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX26642.1 - 2.9e-08 33.9 6.9 1.8e-07 31.3 6.9 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAX26642.1 - 9.9e-08 31.6 1.4 2.5e-07 30.3 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX26642.1 - 2.6e-07 30.4 2.6 2.6e-07 30.4 2.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX26642.1 - 4.2e-07 29.9 2.0 1.1e-06 28.6 2.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 GAX26642.1 - 4.5e-06 26.2 2.3 1.2e-05 24.8 2.3 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX26642.1 - 6.1e-06 26.0 5.5 1.7e-05 24.6 5.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAX26642.1 - 6.3e-06 26.0 3.1 1.4e-05 24.9 3.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAX26642.1 - 6.6e-06 25.9 3.2 6.6e-06 25.9 3.2 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX26642.1 - 0.00053 20.1 2.6 0.0025 18.0 2.6 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 GAX26642.1 - 0.00073 19.5 2.0 0.0022 18.0 2.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 GAX26642.1 - 0.013 15.4 3.4 0.061 13.3 3.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Vps39_2 PF10367.9 GAX26642.1 - 0.015 15.7 0.6 0.07 13.6 0.2 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Glyco_tran_10_N PF17039.5 GAX26642.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal RINGv PF12906.7 GAX26642.1 - 0.045 13.9 3.3 0.17 12.0 3.3 2.1 1 1 0 1 1 1 0 RING-variant domain Rtf2 PF04641.12 GAX26642.1 - 0.08 12.3 0.3 0.08 12.3 0.3 2.2 3 0 0 3 3 3 0 Rtf2 RING-finger zf-Nse PF11789.8 GAX26642.1 - 0.084 12.7 1.4 0.19 11.6 0.5 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit BSP_II PF05432.11 GAX26642.1 - 0.094 12.4 0.6 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PHD PF00628.29 GAX26642.1 - 0.25 11.3 2.8 0.59 10.1 2.8 1.7 1 0 0 1 1 1 0 PHD-finger Pan_kinase PF03309.14 GAX26643.1 - 4.9e-17 62.5 0.1 7.4e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 Type III pantothenate kinase AT_hook PF02178.19 GAX26643.1 - 1.7e-06 27.2 55.8 0.049 13.5 3.0 6.1 6 0 0 6 6 6 5 AT hook motif LBR_tudor PF09465.10 GAX26643.1 - 0.08 12.8 1.4 0.17 11.7 1.4 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Hamartin PF04388.12 GAX26643.1 - 2 7.0 9.3 3.2 6.3 9.3 1.3 1 0 0 1 1 1 0 Hamartin protein ORC6 PF05460.13 GAX26643.1 - 9.5 5.4 20.1 1.1e+02 1.8 16.5 3.1 2 1 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) SIS PF01380.22 GAX26644.1 - 4.8e-33 113.8 0.1 7.6e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAX26644.1 - 1.8e-22 80.0 0.0 4.2e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAX26644.1 - 4.5e-16 58.9 0.0 1.2e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAX26644.1 - 6.6e-06 25.2 0.1 1.4e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II NMT1 PF09084.11 GAX26645.1 - 2.8e-48 164.7 0.0 3.4e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 GAX26645.1 - 0.0062 16.3 0.0 0.068 12.9 0.0 2.1 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 GAX26645.1 - 0.044 13.4 0.0 0.15 11.6 0.0 1.9 1 1 1 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 GAX26646.1 - 6.9e-50 170.0 0.0 8.8e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 GAX26646.1 - 0.015 15.0 0.1 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 NMT1-like family NMT1 PF09084.11 GAX26647.1 - 1.4e-45 155.9 0.0 1.8e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like cobW PF02492.19 GAX26647.1 - 0.073 12.7 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-MYND PF01753.18 GAX26649.1 - 3.4e-05 23.8 18.9 3.4e-05 23.8 18.9 1.9 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 GAX26650.1 - 1.5e-05 25.0 16.9 3.2e-05 23.9 16.9 1.6 1 0 0 1 1 1 1 MYND finger ABC_tran PF00005.27 GAX26651.1 - 2.8e-42 144.5 10.4 6.5e-22 78.5 0.1 3.5 4 0 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 GAX26651.1 - 5.4e-14 52.7 4.6 0.01 15.7 0.3 5.1 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX26651.1 - 8.4e-09 35.2 12.0 0.00066 19.2 0.2 4.8 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAX26651.1 - 6.5e-08 32.6 0.0 0.012 15.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAX26651.1 - 6.2e-07 29.1 0.9 0.018 14.8 0.4 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAX26651.1 - 3.5e-06 27.0 0.9 0.064 13.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 GAX26651.1 - 9.2e-06 25.0 0.1 0.063 12.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_15 PF13175.6 GAX26651.1 - 1.4e-05 25.0 0.0 0.054 13.2 0.2 3.7 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 GAX26651.1 - 2.1e-05 24.5 0.4 0.071 13.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Roc PF08477.13 GAX26651.1 - 3.8e-05 23.9 0.2 0.37 11.0 0.0 3.0 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran_Xtn PF12848.7 GAX26651.1 - 7.5e-05 22.7 11.3 7.5e-05 22.7 11.3 3.4 4 0 0 4 4 3 1 ABC transporter MeaB PF03308.16 GAX26651.1 - 0.00019 20.5 0.1 0.13 11.2 0.0 2.8 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 GAX26651.1 - 0.0017 18.5 0.9 0.96 9.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAX26651.1 - 0.0022 18.4 8.8 0.58 10.5 0.1 3.3 3 1 0 3 3 2 2 AAA ATPase domain NB-ARC PF00931.22 GAX26651.1 - 0.0024 17.1 0.1 0.69 9.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 GAX26651.1 - 0.0026 18.0 9.1 0.048 13.9 0.2 3.8 3 2 1 4 4 3 1 AAA domain RNA_helicase PF00910.22 GAX26651.1 - 0.0028 18.0 0.1 2.4 8.6 0.1 2.9 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 GAX26651.1 - 0.0035 17.3 0.1 3.5 7.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAX26651.1 - 0.0035 16.9 0.1 0.71 9.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 GAX26651.1 - 0.0048 17.4 0.5 2 8.9 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX26651.1 - 0.0066 16.2 0.5 4.5 6.9 0.1 3.3 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.25 GAX26651.1 - 0.0069 16.1 0.0 1.2 8.8 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 GAX26651.1 - 0.007 16.8 0.9 6.1 7.3 0.2 3.8 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAX26651.1 - 0.0089 16.3 5.1 0.15 12.3 0.0 3.8 3 1 0 3 3 3 1 AAA domain KAP_NTPase PF07693.14 GAX26651.1 - 0.011 15.1 0.2 0.17 11.1 0.0 2.8 2 1 0 2 2 2 0 KAP family P-loop domain SbcCD_C PF13558.6 GAX26651.1 - 0.013 15.7 0.7 1.1 9.5 0.3 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Ras PF00071.22 GAX26651.1 - 0.036 13.7 0.1 6.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Ras family NTPase_1 PF03266.15 GAX26651.1 - 0.052 13.4 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 GAX26651.1 - 0.13 12.0 0.3 14 5.4 0.1 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 GAX26651.1 - 0.24 11.5 12.3 2.9 7.9 0.0 4.0 4 0 0 4 4 4 0 Helicase HerA, central domain TsaE PF02367.17 GAX26651.1 - 0.24 11.4 2.2 7.4 6.6 0.3 3.0 2 2 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 GAX26651.1 - 2 8.1 5.2 33 4.1 0.0 3.7 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 GAX26651.1 - 2.5 8.6 20.7 0.78 10.2 0.1 5.0 5 0 0 5 5 5 0 AAA domain DUF1744 PF08490.12 GAX26653.1 - 2.6e-67 227.2 0.0 5.1e-67 226.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 GAX26653.1 - 9.8e-57 192.6 0.0 1.8e-56 191.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 GAX26653.1 - 5.6e-13 48.4 0.0 2.3e-11 43.1 0.0 3.1 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 GAX26653.1 - 2.5e-07 30.6 0.6 1.1e-06 28.5 0.6 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 GAX26653.1 - 3.8e-06 27.0 2.9 6.1e-06 26.3 0.0 2.8 3 0 0 3 3 3 1 RNase_H superfamily NAPRTase_C PF17956.1 GAX26653.1 - 0.08 13.4 0.1 0.46 10.9 0.0 2.3 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain PHD PF00628.29 GAX26653.1 - 1.7 8.6 4.4 3.9 7.4 4.4 1.6 1 0 0 1 1 1 0 PHD-finger MAJIN PF15077.6 GAX26653.1 - 2 8.1 4.7 2.8 7.7 2.3 2.2 2 0 0 2 2 2 0 Membrane-anchored junction protein Topo-VIb_trans PF09239.11 GAX26654.1 - 3.8e-53 179.6 0.0 9.2e-53 178.3 0.0 1.7 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.6 GAX26654.1 - 1.2e-07 31.7 0.3 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAX26654.1 - 1.1e-06 29.2 0.0 3.6e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-MYND PF01753.18 GAX26655.1 - 0.008 16.2 12.1 0.017 15.2 12.1 1.6 1 0 0 1 1 1 1 MYND finger YycC PF14174.6 GAX26655.1 - 0.27 11.1 0.5 2.5 7.9 0.0 2.6 3 0 0 3 3 3 0 YycC-like protein Guanylate_cyc PF00211.20 GAX26656.1 - 1.5e-44 151.8 0.0 4e-44 150.4 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX26656.1 - 2.7e-30 105.8 7.4 7.4e-30 104.4 7.4 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 GAX26656.1 - 0.0069 16.3 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 CHASE domain COX14 PF14880.6 GAX26656.1 - 0.028 14.3 1.0 0.71 9.8 0.5 2.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Bac_GH3_C PF18034.1 GAX26656.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain Orf78 PF06024.12 GAX26656.1 - 3.6 7.9 4.8 1.5 9.2 0.1 2.8 4 0 0 4 4 4 0 Orf78 (ac78) Glyco_hydro_16 PF00722.21 GAX26657.1 - 3.2e-14 52.8 0.1 4.6e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAX26657.1 - 9.4e-08 30.9 2.8 1.1e-07 30.7 2.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TPR_1 PF00515.28 GAX26658.1 - 5.6e-06 26.0 0.4 0.011 15.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX26658.1 - 3.5e-05 23.7 0.1 0.38 11.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26658.1 - 6.9e-05 22.7 0.3 0.16 12.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX26658.1 - 0.00066 19.5 0.2 0.23 11.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF5438 PF17506.2 GAX26658.1 - 0.041 14.2 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5438) TPR_12 PF13424.6 GAX26658.1 - 0.061 13.6 0.1 4.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SET PF00856.28 GAX26662.1 - 3.7e-13 50.2 0.0 4.3e-06 27.2 0.0 4.5 2 2 0 2 2 2 2 SET domain SAF PF08666.12 GAX26662.1 - 0.00082 20.0 0.0 5.3 7.7 0.0 3.8 4 0 0 4 4 4 2 SAF domain AChE_tetra PF08674.10 GAX26662.1 - 0.43 10.3 3.8 1 9.1 3.8 1.6 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Na_H_Exchanger PF00999.21 GAX26663.1 - 3.3e-71 240.1 25.7 4e-71 239.8 25.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 7tm_3 PF00003.22 GAX26664.1 - 2.1e-36 125.9 20.8 2.8e-36 125.4 20.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX26664.1 - 5.4e-23 81.9 0.0 1e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain DUF4834 PF16118.5 GAX26664.1 - 0.023 15.6 0.0 0.086 13.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF267 PF03268.14 GAX26664.1 - 0.75 8.6 9.0 3.6 6.3 4.7 2.3 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 GWT1 PF06423.12 GAX26664.1 - 6.4 6.9 9.1 1.3e+02 2.6 9.0 2.6 1 1 0 1 1 1 0 GWT1 ABC2_membrane_5 PF13346.6 GAX26664.1 - 9.3 5.7 21.0 6 6.4 5.6 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein SANT_DAMP1_like PF16282.5 GAX26666.1 - 3.4e-24 84.8 0.2 5.9e-24 84.1 0.2 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 ATP_bind_1 PF03029.17 GAX26667.1 - 3.4e-36 125.3 0.4 5e-35 121.4 0.4 2.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 GAX26667.1 - 0.0039 17.7 0.0 0.014 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_pol PF00940.19 GAX26667.1 - 0.0091 14.9 0.0 0.089 11.6 0.1 2.2 2 1 0 2 2 2 1 DNA-dependent RNA polymerase RNA_helicase PF00910.22 GAX26667.1 - 0.02 15.3 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.7 GAX26667.1 - 0.021 13.7 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.6 GAX26667.1 - 0.036 14.5 0.2 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAX26667.1 - 0.046 14.0 0.0 0.13 12.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAX26667.1 - 0.06 13.5 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAX26667.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX26667.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAX26667.1 - 0.11 12.9 0.1 0.28 11.6 0.1 1.9 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 GAX26667.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase IstB_IS21 PF01695.17 GAX26667.1 - 0.15 11.8 0.1 17 5.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein SRP54 PF00448.22 GAX26667.1 - 0.22 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DNA_processg_A PF02481.15 GAX26669.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A AAA_33 PF13671.6 GAX26670.1 - 0.00011 22.4 0.0 0.0002 21.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX26670.1 - 0.00012 22.3 0.0 0.00032 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX26670.1 - 0.00015 22.3 0.3 0.72 10.4 0.3 2.4 1 1 1 2 2 2 2 ABC transporter SMC_N PF02463.19 GAX26670.1 - 0.0015 18.1 0.6 0.35 10.3 0.0 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX26670.1 - 0.0075 16.1 1.3 2.7 7.7 1.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 GAX26670.1 - 0.01 15.0 0.1 0.028 13.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 GAX26670.1 - 0.018 15.4 0.1 0.052 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Wzy_C PF04932.15 GAX26670.1 - 0.032 13.8 0.1 0.032 13.8 0.1 2.5 2 1 0 2 2 2 0 O-Antigen ligase cobW PF02492.19 GAX26670.1 - 0.037 13.6 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAX26670.1 - 0.047 13.6 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 GAX26670.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 GAX26670.1 - 0.11 12.7 0.2 1.8 8.8 0.0 2.7 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase LapA_dom PF06305.11 GAX26670.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain AAA_29 PF13555.6 GAX26670.1 - 0.13 12.0 0.3 0.4 10.4 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cyto_heme_lyase PF01265.17 GAX26671.1 - 6.2e-48 163.9 5.4 6.2e-48 163.9 5.4 2.2 1 1 1 2 2 2 1 Cytochrome c/c1 heme lyase DUF676 PF05057.14 GAX26672.1 - 9.6e-25 87.4 0.0 8.7e-21 74.4 0.0 2.3 1 1 1 2 2 2 2 Putative serine esterase (DUF676) LigB PF02900.18 GAX26674.1 - 2.2e-43 148.3 0.0 2.6e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LAGLIDADG_3 PF14528.6 GAX26674.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 LAGLIDADG-like domain Guanylate_cyc PF00211.20 GAX26675.1 - 7.4e-45 152.8 0.0 1.3e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX26675.1 - 1.5e-29 103.4 8.4 4.2e-29 102.0 8.4 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Bac_GH3_C PF18034.1 GAX26675.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain HSBP1 PF06825.12 GAX26676.1 - 2.1 8.3 5.4 13 5.7 0.2 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Phage_holin_3_1 PF05106.12 GAX26677.1 - 0.062 13.7 0.2 0.23 11.9 0.2 1.9 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) SLC35F PF06027.12 GAX26679.1 - 9.1e-41 140.3 14.6 1.5e-38 133.0 10.2 2.0 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 GAX26679.1 - 9.5e-11 41.2 0.4 2.4e-10 39.9 0.4 1.8 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAX26679.1 - 1.6e-10 41.3 24.7 1e-05 25.7 6.1 2.9 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 GAX26679.1 - 3.9e-08 32.9 6.8 4.4e-08 32.7 4.8 1.9 2 0 0 2 2 2 1 UAA transporter family Nuc_sug_transp PF04142.15 GAX26679.1 - 0.00013 21.2 0.2 0.03 13.5 0.1 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter Mg_trans_NIPA PF05653.14 GAX26679.1 - 0.00014 21.1 0.2 0.00014 21.1 0.2 2.0 3 0 0 3 3 3 1 Magnesium transporter NIPA DUF1761 PF08570.10 GAX26679.1 - 0.46 10.7 9.0 1.2 9.5 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1761) DUF4131 PF13567.6 GAX26679.1 - 1.6 8.3 5.2 0.92 9.1 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Nucleotid_trans PF03407.16 GAX26680.1 - 0.0027 17.7 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.20 GAX26680.1 - 0.011 15.3 2.0 0.3 10.6 0.3 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAX26680.1 - 0.16 11.3 0.2 0.25 10.7 0.2 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Sec7 PF01369.20 GAX26681.1 - 0.079 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Sec7 domain API5 PF05918.11 GAX26681.1 - 0.12 11.2 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) SET PF00856.28 GAX26682.1 - 2.3e-06 28.1 0.0 5.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 SET domain SAP30_Sin3_bdg PF13867.6 GAX26682.1 - 0.041 14.2 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Vps52 PF04129.12 GAX26683.1 - 3.2e-86 290.1 5.7 1.5e-83 281.3 0.2 2.4 3 0 0 3 3 3 2 Vps52 / Sac2 family Sec3_C PF09763.9 GAX26683.1 - 1.8e-13 49.9 9.2 5.9e-13 48.1 3.4 2.7 2 1 0 2 2 2 2 Exocyst complex component Sec3 COG6 PF06419.11 GAX26683.1 - 1.1e-06 27.1 4.5 0.0061 14.8 0.7 2.4 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 CHDCT2 PF08074.11 GAX26683.1 - 0.0062 16.7 1.0 0.44 10.7 0.3 3.5 3 1 0 3 3 3 1 CHDCT2 (NUC038) domain Spc7 PF08317.11 GAX26683.1 - 0.014 14.3 0.8 0.014 14.3 0.8 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 GAX26683.1 - 0.024 14.7 0.4 0.024 14.7 0.4 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) COG2 PF06148.11 GAX26683.1 - 0.033 14.3 1.9 0.33 11.0 0.3 3.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spidroin_N PF16763.5 GAX26683.1 - 0.042 13.9 0.1 2.2 8.3 0.0 3.0 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term SKA2 PF16740.5 GAX26683.1 - 0.054 13.3 0.2 0.054 13.3 0.2 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 SpoVT_C PF15714.5 GAX26683.1 - 0.063 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor CTK3 PF12243.8 GAX26683.1 - 0.091 12.8 0.4 0.99 9.4 0.0 2.7 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 HAP1_N PF04849.13 GAX26683.1 - 0.31 10.2 7.1 0.26 10.4 1.3 2.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Peptidase_S10 PF00450.22 GAX26684.1 - 4.3e-85 286.6 0.0 5.5e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase LIP PF03583.14 GAX26684.1 - 0.18 11.1 0.2 0.55 9.5 0.0 1.8 2 0 0 2 2 2 0 Secretory lipase TPR_12 PF13424.6 GAX26686.1 - 0.0017 18.6 4.0 0.61 10.4 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX26686.1 - 1.5 8.8 4.5 5 7.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 GAX26687.1 - 7.4e-54 182.9 0.0 9.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26687.1 - 1.4e-21 77.0 0.0 2.9e-21 75.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX26687.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX26687.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAX26687.1 - 0.014 14.3 0.0 0.061 12.3 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Big_3_3 PF13750.6 GAX26687.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) PP2C PF00481.21 GAX26688.1 - 5.7e-34 117.9 0.0 7.4e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX26688.1 - 0.00016 21.7 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Tyr_Deacylase PF02580.16 GAX26689.1 - 2.7e-47 160.9 0.0 3.1e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase eIF3_subunit PF08597.10 GAX26690.1 - 4.3e-24 85.8 35.5 5.3e-24 85.5 35.5 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit EF-hand_10 PF14788.6 GAX26690.1 - 0.054 13.4 0.4 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 EF hand PALP PF00291.25 GAX26691.1 - 1.8e-60 204.9 0.3 4.4e-60 203.6 0.3 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_26 PF13500.6 GAX26691.1 - 0.038 13.8 0.3 0.22 11.3 0.2 2.0 2 0 0 2 2 2 0 AAA domain DUF4225 PF13988.6 GAX26691.1 - 0.079 12.5 0.1 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4225) Macoilin PF09726.9 GAX26692.1 - 0.0013 17.4 5.5 0.0015 17.2 5.5 1.1 1 0 0 1 1 1 1 Macoilin family TTSSLRR PF12468.8 GAX26692.1 - 0.3 11.4 4.0 0.26 11.6 0.3 2.7 3 0 0 3 3 3 0 Type III secretion system leucine rich repeat protein Inhibitor_I71 PF12628.7 GAX26695.1 - 0.1 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor RNA_pol_Rpc4 PF05132.14 GAX26695.1 - 7.2 7.0 9.2 9.4 6.6 1.5 3.1 3 1 0 3 3 3 0 RNA polymerase III RPC4 Hydrolase_4 PF12146.8 GAX26696.1 - 8.2e-11 41.6 0.1 4.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAX26696.1 - 1.5e-07 32.2 0.0 2.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX26696.1 - 2.7e-05 23.9 0.0 4.6e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 GAX26696.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 GAX26696.1 - 0.0022 17.5 0.3 0.068 12.6 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAX26696.1 - 0.0071 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 GAX26696.1 - 0.02 14.8 0.2 0.033 14.1 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 GAX26696.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase TPR_10 PF13374.6 GAX26697.1 - 4e-06 26.5 3.2 9.9e-05 22.1 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26697.1 - 0.0022 18.0 0.5 0.04 14.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX26697.1 - 0.059 13.2 0.6 0.23 11.3 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX26697.1 - 0.12 12.7 0.4 0.75 10.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX26697.1 - 0.13 12.9 0.1 0.99 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX26697.1 - 0.15 12.7 0.5 0.34 11.6 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF296 PF03479.15 GAX26698.1 - 1.9e-24 86.1 0.3 2.3e-24 85.8 0.3 1.1 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain DUF3551 PF12071.8 GAX26699.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) TraB PF01963.17 GAX26702.1 - 3.1e-17 63.4 2.0 2.2e-09 37.6 1.1 2.4 2 1 0 2 2 2 2 TraB family TPR_1 PF00515.28 GAX26703.1 - 0.068 13.0 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3878 PF12994.7 GAX26703.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) DUF179 PF02622.15 GAX26704.1 - 6.2e-10 39.3 0.0 9.8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 FAM176 PF14851.6 GAX26704.1 - 0.016 14.8 0.3 0.026 14.2 0.3 1.2 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 GAX26704.1 - 0.029 12.5 2.2 0.036 12.2 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myc_N PF01056.18 GAX26704.1 - 0.054 13.4 1.2 0.074 12.9 0.4 1.6 2 0 0 2 2 2 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 GAX26704.1 - 0.55 10.7 10.2 1 9.8 10.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BSMAP PF12280.8 GAX26705.1 - 0.0011 19.3 1.8 0.063 13.5 0.0 2.1 2 0 0 2 2 2 1 Brain specific membrane anchored protein Tugs PF17840.1 GAX26705.1 - 0.059 13.6 1.6 0.065 13.4 0.2 1.7 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain AnfO_nitrog PF09582.10 GAX26705.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Nop53 PF07767.11 GAX26705.1 - 0.3 10.4 13.9 0.081 12.3 10.0 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 GAX26705.1 - 0.45 10.5 21.5 0.77 9.7 21.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 GAX26705.1 - 0.45 8.7 7.8 0.73 8.1 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAX26705.1 - 1.4 7.1 13.5 2.3 6.3 13.5 1.3 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.6 GAX26705.1 - 2.8 7.8 17.4 0.75 9.7 14.4 1.5 2 0 0 2 2 2 0 Spore coat protein CotO TRAP_alpha PF03896.16 GAX26705.1 - 5.8 6.0 7.7 8.7 5.5 7.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF913 PF06025.12 GAX26705.1 - 7.5 5.4 6.4 12 4.7 6.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Plus-3 PF03126.18 GAX26706.1 - 3.4e-24 85.5 0.0 9.3e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Plus-3 domain Glyco_hydro_72 PF03198.14 GAX26708.1 - 1.1e-59 202.2 0.3 1.6e-59 201.8 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 GAX26708.1 - 0.0037 16.7 0.0 0.023 14.1 0.0 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mito_carr PF00153.27 GAX26709.1 - 2.3e-35 120.4 7.0 1.1e-19 70.1 0.5 4.7 5 1 0 5 5 5 4 Mitochondrial carrier protein DUF2501 PF10696.9 GAX26709.1 - 0.081 13.2 0.0 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2501) Fumble PF03630.14 GAX26710.1 - 3.9e-110 368.1 1.5 1.5e-108 362.9 1.5 2.7 1 1 0 1 1 1 1 Fumble DUF1943 PF09172.11 GAX26710.1 - 0.0089 15.3 0.2 0.016 14.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Methyltransf_17 PF12692.7 GAX26710.1 - 0.041 13.9 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Nab6_mRNP_bdg PF10567.9 GAX26710.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 RNA-recognition motif DUF4090 PF13319.6 GAX26711.1 - 0.15 12.3 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) PBP1_TM PF14812.6 GAX26712.1 - 5.3 7.5 7.8 2.1 8.8 1.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GRP PF07172.11 GAX26713.1 - 0.006 17.3 9.4 0.012 16.3 9.4 1.5 1 0 0 1 1 1 1 Glycine rich protein family LCAT PF02450.15 GAX26714.1 - 3.8e-45 154.7 0.0 7.5e-27 94.5 0.0 2.5 2 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase zf-C2H2_4 PF13894.6 GAX26715.1 - 1.4e-11 44.2 32.6 0.0064 17.2 0.2 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger CpXC PF14353.6 GAX26715.1 - 1.4e-06 28.4 19.1 0.06 13.4 0.3 5.8 5 1 1 6 6 5 2 CpXC protein zf-C2H2 PF00096.26 GAX26715.1 - 1.5e-06 28.3 34.6 0.022 15.2 1.3 6.5 6 0 0 6 6 5 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 GAX26715.1 - 9.5e-06 25.3 17.5 0.06 13.1 0.2 5.1 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 GAX26715.1 - 1.9e-05 24.8 14.9 0.008 16.4 0.9 5.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 GAX26715.1 - 0.00035 20.8 18.7 6.3 7.2 0.0 7.0 7 0 0 7 7 6 1 zinc-ribbon C1_1 PF00130.22 GAX26715.1 - 0.0019 18.0 1.2 0.0019 18.0 1.2 5.1 6 0 0 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 GAX26715.1 - 0.0036 17.2 5.0 0.0036 17.2 5.0 3.4 4 0 0 4 4 3 1 PHD-finger C1_2 PF03107.16 GAX26715.1 - 0.0054 17.0 0.7 0.0054 17.0 0.7 4.7 5 0 0 5 5 4 1 C1 domain zf-RING_7 PF02591.15 GAX26715.1 - 0.0081 16.3 7.8 9.6 6.5 0.4 4.6 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2H2_2 PF12756.7 GAX26715.1 - 0.022 15.1 16.9 0.83 10.0 0.2 5.6 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-HC5HC2H_2 PF13832.6 GAX26715.1 - 0.023 14.8 0.3 0.023 14.8 0.3 3.5 3 1 0 3 3 3 0 PHD-zinc-finger like domain Zn-C2H2_12 PF18112.1 GAX26715.1 - 0.024 15.1 2.4 13 6.4 0.0 4.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 GAX26715.1 - 0.092 13.2 1.9 2.7 8.5 0.1 4.0 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 GAX26715.1 - 0.16 12.1 24.4 0.9 9.7 0.1 5.7 6 0 0 6 6 6 0 Aberrant zinc-finger zf-met PF12874.7 GAX26715.1 - 0.32 11.4 12.4 6 7.4 0.9 5.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type YhfH PF14149.6 GAX26715.1 - 0.43 10.6 10.1 5 7.2 0.0 4.8 5 0 0 5 5 4 0 YhfH-like protein Zf_RING PF16744.5 GAX26715.1 - 0.69 10.1 4.7 0.27 11.4 0.5 2.6 2 0 0 2 2 1 0 KIAA1045 RING finger zf-BED PF02892.15 GAX26715.1 - 0.73 9.9 8.2 6.9 6.8 0.3 3.7 3 0 0 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.6 GAX26715.1 - 0.9 9.5 10.9 1.6 8.7 0.4 4.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PHD_4 PF16866.5 GAX26715.1 - 2.2 8.4 10.6 0.41 10.8 3.6 3.5 3 0 0 3 3 3 0 PHD-finger zf-PHD-like PF15446.6 GAX26715.1 - 3.8 7.1 14.4 0.013 15.2 2.5 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF2256 PF10013.9 GAX26715.1 - 6 7.1 18.6 2.2 8.5 0.2 5.5 6 0 0 6 6 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Coprogen_oxidas PF01218.18 GAX26716.1 - 4e-132 439.4 0.5 4.8e-132 439.2 0.5 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Mod_r PF07200.13 GAX26718.1 - 0.017 15.2 4.3 0.017 15.2 4.3 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_12 PF13424.6 GAX26718.1 - 0.027 14.7 0.2 0.1 12.9 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_tranf_2_4 PF13704.6 GAX26719.1 - 0.00013 22.4 0.6 0.0004 20.9 0.6 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF2358 PF10184.9 GAX26720.1 - 6.3e-12 45.8 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) WAP PF00095.21 GAX26720.1 - 0.026 14.9 5.0 0.026 14.9 5.0 1.7 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' TPR_7 PF13176.6 GAX26721.1 - 0.00071 19.4 0.1 0.27 11.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX26721.1 - 0.0079 16.5 0.1 6.2 7.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat PPR PF01535.20 GAX26721.1 - 0.0089 16.2 1.2 0.03 14.6 0.1 2.5 3 0 0 3 3 3 1 PPR repeat TPR_1 PF00515.28 GAX26721.1 - 0.014 15.2 0.8 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4808 PF16066.5 GAX26721.1 - 0.037 14.6 1.3 0.28 11.7 1.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4808) TPR_2 PF07719.17 GAX26721.1 - 0.11 12.7 0.7 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PI-PLC-X PF00388.19 GAX26722.1 - 2.5e-10 40.1 0.0 6.4e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HMG_box PF00505.19 GAX26723.1 - 8.6e-09 35.7 4.2 2.5e-05 24.6 0.0 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX26723.1 - 3.2e-07 30.8 6.4 1.6e-06 28.6 2.2 2.9 1 1 1 2 2 2 1 HMG-box domain PEPCK_ATP PF01293.20 GAX26723.1 - 0.051 12.3 0.1 0.065 11.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase YABBY PF04690.13 GAX26723.1 - 0.86 10.1 4.8 0.63 10.6 0.1 2.1 2 0 0 2 2 2 0 YABBY protein HMG_box PF00505.19 GAX26724.1 - 2.5e-08 34.2 8.2 0.00017 22.0 0.1 3.6 2 1 1 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX26724.1 - 1.4e-06 28.8 10.5 9.8e-06 26.1 2.6 3.4 1 1 1 2 2 2 1 HMG-box domain HDV_ag PF01517.18 GAX26724.1 - 0.0072 16.2 0.5 0.016 15.0 0.5 1.6 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen YABBY PF04690.13 GAX26724.1 - 4.2 7.9 13.8 0.067 13.8 1.0 3.0 2 1 2 4 4 4 0 YABBY protein HMG_box PF00505.19 GAX26725.1 - 1.3e-05 25.5 11.4 0.00088 19.6 0.1 3.4 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX26725.1 - 0.00018 22.0 3.5 0.00018 22.0 3.5 3.2 1 1 1 2 2 2 1 HMG-box domain Nop52 PF05997.12 GAX26725.1 - 0.033 14.0 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 Nucleolar protein,Nop52 YABBY PF04690.13 GAX26725.1 - 0.25 11.9 4.4 0.26 11.8 0.1 2.1 2 0 0 2 2 2 0 YABBY protein HI0933_like PF03486.14 GAX26726.1 - 6.3e-105 351.2 0.0 8.7e-105 350.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 GAX26726.1 - 2.1e-12 46.8 4.3 4.8e-10 39.1 4.3 3.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAX26726.1 - 2.2e-11 43.9 3.6 4.5e-05 23.2 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX26726.1 - 1.4e-09 37.6 7.5 1.1e-06 28.1 1.1 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX26726.1 - 1.8e-06 27.6 0.1 2.5e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAX26726.1 - 2e-05 23.8 8.0 0.0033 16.6 4.0 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAX26726.1 - 4.4e-05 22.9 0.2 7.7e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 GAX26726.1 - 6.3e-05 23.1 0.6 0.00016 21.8 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAX26726.1 - 0.00033 20.0 0.6 0.0028 17.0 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX26726.1 - 0.00035 21.1 1.1 0.0017 18.9 0.5 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAX26726.1 - 0.00096 18.5 0.9 0.24 10.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 GAX26726.1 - 0.0066 15.6 0.2 2.7 7.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 GAX26726.1 - 0.04 13.8 1.6 0.074 12.9 1.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 GAX26726.1 - 0.041 13.1 0.6 0.23 10.7 0.2 2.2 3 0 0 3 3 3 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 GAX26726.1 - 0.066 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 GAX26726.1 - 0.087 12.8 0.4 0.2 11.7 0.4 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAX26726.1 - 0.31 9.8 2.2 0.49 9.2 2.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase RRF PF01765.19 GAX26727.1 - 8.4e-34 116.9 0.7 8.4e-34 116.9 0.7 1.9 2 0 0 2 2 2 1 Ribosome recycling factor IPK PF03770.16 GAX26727.1 - 0.07 13.0 1.1 0.12 12.3 1.1 1.3 1 0 0 1 1 1 0 Inositol polyphosphate kinase DUF4746 PF15928.5 GAX26727.1 - 0.2 11.0 14.1 0.32 10.4 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CDT1_C PF16679.5 GAX26727.1 - 1.4 9.4 10.3 16 6.0 6.0 3.0 2 1 1 3 3 3 0 DNA replication factor Cdt1 C-terminal domain RNA_pol_Rpc4 PF05132.14 GAX26727.1 - 4.8 7.6 9.2 1.2 9.6 5.4 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 SdrD_B PF17210.3 GAX26728.1 - 1.8e-115 379.2 33.5 1.6e-16 60.5 0.0 8.4 8 0 0 8 8 8 8 SdrD B-like domain SpaA PF17802.1 GAX26728.1 - 9.3e-12 45.1 4.6 0.58 10.5 0.1 7.6 8 0 0 8 8 8 3 Prealbumin-like fold domain VWD PF00094.25 GAX26728.1 - 6.9e-10 39.4 0.2 2.5e-09 37.6 0.2 2.0 1 1 0 1 1 1 1 von Willebrand factor type D domain CarboxypepD_reg PF13620.6 GAX26728.1 - 5.1e-06 26.7 13.3 1.1 9.6 0.3 7.4 8 0 0 8 8 8 2 Carboxypeptidase regulatory-like domain DUF1939 PF09154.10 GAX26728.1 - 5.3e-05 23.3 1.1 0.39 10.9 0.0 5.3 5 0 0 5 5 5 1 Domain of unknown function (DUF1939) Toxin_35 PF10530.9 GAX26728.1 - 0.0058 16.6 5.9 0.0058 16.6 5.9 7.7 3 2 4 8 8 8 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_12 PF07740.12 GAX26728.1 - 0.0077 16.9 4.8 0.0077 16.9 4.8 8.4 9 0 0 9 9 9 2 Ion channel inhibitory toxin DUF2141 PF09912.9 GAX26728.1 - 0.066 13.1 7.9 0.13 12.2 0.0 4.6 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF4124 PF13511.6 GAX26728.1 - 1.6 9.1 3.7 1.9e+02 2.4 0.2 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4124) Thioredoxin_8 PF13905.6 GAX26729.1 - 2.4e-19 69.4 0.0 4.5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GAX26729.1 - 0.015 15.5 0.1 0.34 11.1 0.0 2.7 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX26729.1 - 0.02 15.3 0.0 0.49 10.9 0.0 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain RskA PF10099.9 GAX26729.1 - 0.071 13.4 0.5 0.11 12.8 0.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA AhpC-TSA PF00578.21 GAX26729.1 - 0.18 11.7 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family DUF2992 PF11208.8 GAX26729.1 - 0.69 10.2 5.9 13 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) ECH_1 PF00378.20 GAX26730.1 - 2.5e-33 115.4 0.0 3.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX26730.1 - 1.5e-16 60.8 0.1 7.1e-16 58.6 0.0 1.8 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase TAXi_N PF14543.6 GAX26731.1 - 2.7e-16 60.3 1.4 4.5e-16 59.6 1.4 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAX26731.1 - 7.7e-11 42.0 0.1 0.071 12.5 0.2 3.9 3 1 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAX26731.1 - 0.0069 16.2 0.0 8.5 6.1 0.0 3.3 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Lipase_GDSL_2 PF13472.6 GAX26733.1 - 4.7e-17 62.9 0.1 5.7e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX26733.1 - 1e-11 45.2 0.0 1.4e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CP12 PF02672.15 GAX26733.1 - 0.16 12.8 0.1 0.91 10.3 0.0 1.9 2 0 0 2 2 2 0 CP12 domain Lipase_GDSL_2 PF13472.6 GAX26734.1 - 2.9e-16 60.4 0.0 3.6e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX26734.1 - 2e-12 47.5 0.0 3.3e-12 46.8 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 GAX26734.1 - 0.023 13.9 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 OSK domain CP12 PF02672.15 GAX26734.1 - 0.14 12.9 0.1 0.84 10.4 0.0 1.9 2 0 0 2 2 2 0 CP12 domain Archaeal_AmoA PF12942.7 GAX26735.1 - 0.016 14.9 3.8 0.099 12.3 0.6 2.5 1 1 1 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) BTHB PF18410.1 GAX26736.1 - 0.064 13.1 0.4 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Basic tilted helix bundle domain WD40 PF00400.32 GAX26737.1 - 2e-43 145.5 19.9 7.1e-09 36.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX26737.1 - 3.8e-19 68.8 4.4 2e-05 24.8 0.3 6.2 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX26737.1 - 7.7e-10 39.0 0.5 0.00046 20.1 0.1 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A KH_1 PF00013.29 GAX26737.1 - 4.2e-07 29.7 2.6 7.3e-07 28.9 2.6 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 GAX26737.1 - 0.0015 18.4 0.3 0.0028 17.5 0.3 1.3 1 0 0 1 1 1 1 KH domain Frtz PF11768.8 GAX26737.1 - 0.027 12.8 0.0 10 4.3 0.0 3.0 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz SLS PF14611.6 GAX26737.1 - 0.029 14.2 0.2 0.057 13.2 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Coatomer_WDAD PF04053.14 GAX26737.1 - 0.071 12.1 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region SBD PF17882.1 GAX26737.1 - 0.15 11.9 1.5 2.5 7.9 0.1 3.0 2 1 1 3 3 3 0 OAA-family lectin sugar binding domain KH_2 PF07650.17 GAX26737.1 - 0.21 11.4 1.1 0.39 10.6 1.1 1.4 1 0 0 1 1 1 0 KH domain UAA PF08449.11 GAX26738.1 - 1.7e-35 122.7 7.8 2e-35 122.5 7.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX26738.1 - 0.0005 20.3 9.4 0.0005 20.3 9.4 2.6 2 1 1 3 3 3 1 EamA-like transporter family Ribosomal_60s PF00428.19 GAX26740.1 - 0.021 15.4 7.2 0.2 12.3 0.1 3.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein DUF4061 PF13270.6 GAX26740.1 - 0.039 14.3 14.6 0.059 13.7 5.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) FAM176 PF14851.6 GAX26740.1 - 0.1 12.3 11.1 0.79 9.4 0.1 2.5 2 0 0 2 2 2 0 FAM176 family Macoilin PF09726.9 GAX26740.1 - 0.12 10.9 20.0 0.15 10.6 20.0 1.0 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 GAX26740.1 - 0.17 11.4 13.8 0.015 14.8 5.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit STI1 PF17830.1 GAX26740.1 - 1.1 9.2 6.4 2.8 8.0 0.1 3.0 3 0 0 3 3 3 0 STI1 domain PEP-utilisers_N PF05524.13 GAX26740.1 - 4.2 7.6 13.1 5.7 7.1 0.1 3.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal VIT1 PF01988.19 GAX26740.1 - 4.2 7.2 10.9 0.05 13.5 1.6 2.2 2 1 0 2 2 2 0 VIT family 5_nucleotid PF05761.14 GAX26740.1 - 5.9 5.7 7.6 14 4.4 7.6 1.6 1 0 0 1 1 1 0 5' nucleotidase family DivIVA PF05103.13 GAX26740.1 - 8.5 6.5 18.2 0.8 9.8 13.1 1.9 2 0 0 2 2 2 0 DivIVA protein Actin PF00022.19 GAX26741.1 - 2.7e-70 237.0 0.0 3.4e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Actin BAR PF03114.18 GAX26742.1 - 0.00014 21.6 4.5 0.00018 21.2 4.1 1.4 1 1 0 1 1 1 1 BAR domain POX PF07526.11 GAX26742.1 - 0.00061 20.4 3.2 0.00061 20.4 3.2 2.0 2 0 0 2 2 2 1 Associated with HOX Uds1 PF15456.6 GAX26742.1 - 0.18 12.0 6.2 0.12 12.6 3.6 1.9 2 0 0 2 2 2 0 Up-regulated During Septation Spectrin PF00435.21 GAX26742.1 - 0.2 12.1 7.1 0.21 12.1 1.4 2.9 3 0 0 3 3 3 0 Spectrin repeat LXG PF04740.12 GAX26742.1 - 3.2 7.4 9.5 2.1 8.0 5.0 2.6 2 1 0 2 2 2 0 LXG domain of WXG superfamily APG6_N PF17675.1 GAX26742.1 - 3.8 8.1 7.5 13 6.4 6.2 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region FliD_N PF02465.18 GAX26742.1 - 4.7 8.0 12.1 2.8 8.7 0.9 3.2 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4407 PF14362.6 GAX26742.1 - 5.5 6.3 7.6 0.44 9.8 3.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PAP_fibrillin PF04755.12 GAX26743.1 - 4.3e-07 30.1 0.0 9.8e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 PAP_fibrillin DUF3641 PF12345.8 GAX26744.1 - 8.6e-54 181.2 0.1 1.5e-53 180.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 GAX26744.1 - 4.2e-09 37.0 0.0 7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAX26744.1 - 3.3e-06 27.4 0.0 6.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Arf PF00025.21 GAX26745.1 - 1.3e-45 154.9 0.0 1.6e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAX26745.1 - 1e-13 51.5 0.0 2e-13 50.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX26745.1 - 2.8e-13 49.8 0.0 3.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAX26745.1 - 6e-09 36.0 0.0 9.1e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX26745.1 - 3.6e-08 33.2 0.1 6.4e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAX26745.1 - 4.2e-08 32.8 0.0 5.1e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAX26745.1 - 6.6e-07 28.9 0.0 8.8e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAX26745.1 - 2.4e-06 26.9 0.3 0.00019 20.7 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit cobW PF02492.19 GAX26745.1 - 0.0075 15.9 0.0 0.63 9.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 GAX26745.1 - 0.0075 15.8 0.7 0.28 10.7 0.7 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B 6PF2K PF01591.18 GAX26745.1 - 0.073 12.4 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MMR_HSR1_Xtn PF16897.5 GAX26745.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain preATP-grasp_3 PF18301.1 GAX26745.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain Dynamin_N PF00350.23 GAX26745.1 - 0.099 12.7 0.1 2.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.9 GAX26745.1 - 0.11 12.2 0.1 1.1 8.9 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 GAX26745.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAX26745.1 - 0.18 12.0 0.0 0.46 10.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain Inv-AAD PF18785.1 GAX26746.1 - 3.8e-07 30.0 0.1 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 GAX26746.1 - 4.6e-05 23.2 1.2 0.00014 21.6 0.0 2.5 3 0 0 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region CWC25 PF12542.8 GAX26746.1 - 0.47 11.4 3.1 1.2 10.1 3.1 1.6 1 0 0 1 1 1 0 Pre-mRNA splicing factor TSP_1 PF00090.19 GAX26747.1 - 2.4e-06 27.6 34.2 0.0013 18.9 7.8 4.0 4 1 0 4 4 4 3 Thrombospondin type 1 domain DUF1325 PF07039.11 GAX26748.1 - 4.5e-19 68.8 1.2 7.7e-19 68.1 0.2 1.8 2 0 0 2 2 2 1 SGF29 tudor-like domain ING PF12998.7 GAX26748.1 - 1.4e-15 57.7 2.1 6.7e-15 55.5 2.1 2.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding LBR_tudor PF09465.10 GAX26748.1 - 0.017 14.9 0.0 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain NOG1_N PF17835.1 GAX26748.1 - 0.031 14.2 0.2 0.099 12.6 0.1 1.8 2 0 0 2 2 2 0 NOG1 N-terminal helical domain CHASE3 PF05227.13 GAX26748.1 - 0.036 14.0 0.8 0.036 14.0 0.8 2.2 2 1 0 2 2 2 0 CHASE3 domain Tudor_3 PF18115.1 GAX26748.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Phage_Mu_Gam PF07352.12 GAX26748.1 - 0.31 10.9 4.5 0.091 12.7 1.0 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Defensin_like PF10868.8 GAX26749.1 - 0.00022 21.9 2.6 0.00028 21.6 2.6 1.2 1 0 0 1 1 1 1 Cysteine-rich antifungal protein 2, defensin-like TP6A_N PF04406.14 GAX26750.1 - 1.8e-07 31.0 0.9 1.8e-07 31.0 0.9 1.8 2 0 0 2 2 2 1 Type IIB DNA topoisomerase Nuc_deoxyri_tr3 PF11071.8 GAX26751.1 - 9.7e-61 203.9 0.0 1.2e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase YtoQ Nuc_deoxyri_tr2 PF15891.5 GAX26751.1 - 1.2e-05 25.6 0.0 0.00012 22.3 0.0 2.1 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 GAX26751.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase ubiquitin PF00240.23 GAX26752.1 - 6.4e-22 77.1 0.0 1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX26752.1 - 1.8e-10 40.5 0.0 5.8e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like zf-C3HC4_3 PF13920.6 GAX26752.1 - 2.3e-10 40.2 16.5 4e-10 39.4 16.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX26752.1 - 1.5e-06 27.9 15.6 2.5e-06 27.2 15.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ANTAR PF03861.14 GAX26752.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 ANTAR domain zf-RING_5 PF14634.6 GAX26752.1 - 0.064 13.2 15.9 0.13 12.2 15.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2781 PF10914.8 GAX26753.1 - 6.6e-36 123.9 10.2 8.2e-36 123.6 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) RF-1 PF00472.20 GAX26754.1 - 5.5e-23 81.1 3.6 8e-23 80.6 3.6 1.2 1 0 0 1 1 1 1 RF-1 domain Mito_carr PF00153.27 GAX26755.1 - 6.7e-18 64.4 9.7 7.1e-07 29.1 0.0 4.0 3 2 0 3 3 3 3 Mitochondrial carrier protein ERF PF04404.12 GAX26755.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 ERF superfamily WD40 PF00400.32 GAX26756.1 - 7.5e-05 23.4 6.8 0.012 16.4 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat PMSR PF01625.21 GAX26757.1 - 7.5e-56 188.6 0.8 1e-55 188.1 0.8 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CAF1 PF04857.20 GAX26757.1 - 0.047 12.9 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease ERCC4 PF02732.15 GAX26758.1 - 4.2e-20 72.5 0.0 8.1e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Robl_LC7 PF03259.17 GAX26759.1 - 7e-08 32.1 0.0 1.7e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain sCache_3_2 PF17203.4 GAX26759.1 - 0.083 13.0 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Single cache domain 3 TIP120 PF08623.10 GAX26760.1 - 5.8e-36 123.8 3.0 1.8e-31 109.2 0.0 5.6 5 1 0 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 GAX26760.1 - 3e-14 51.9 16.6 0.033 14.4 0.0 9.5 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 GAX26760.1 - 7.6e-09 35.8 14.0 0.017 15.5 0.3 7.0 6 1 1 7 7 6 2 HEAT repeats RTP1_C1 PF10363.9 GAX26760.1 - 0.00039 20.6 8.3 1.1 9.5 0.4 6.4 7 2 1 8 8 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 GAX26760.1 - 0.0017 18.4 16.4 0.0026 17.8 1.1 6.1 6 3 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX26760.1 - 0.0071 16.8 13.1 14 6.3 0.0 8.5 8 1 2 10 10 9 0 HEAT-like repeat MMS19_N PF14500.6 GAX26760.1 - 0.026 14.1 0.3 0.026 14.1 0.3 4.8 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 GAX26760.1 - 0.035 14.7 0.4 59 4.3 0.0 4.9 5 1 0 5 5 3 0 Vacuolar 14 Fab1-binding region SDA1 PF05285.12 GAX26760.1 - 0.051 13.0 5.8 0.098 12.1 5.8 1.4 1 0 0 1 1 1 0 SDA1 EF-hand_like PF09279.11 GAX26760.1 - 0.11 13.0 0.9 6.5 7.3 0.2 3.0 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Nop14 PF04147.12 GAX26760.1 - 0.11 10.7 10.0 0.31 9.2 10.0 1.7 1 0 0 1 1 1 0 Nop14-like family ParcG PF10274.9 GAX26760.1 - 0.47 10.5 0.0 0.47 10.5 0.0 4.5 5 1 1 6 6 5 0 Parkin co-regulated protein Pox_RNA_Pol_19 PF05320.12 GAX26760.1 - 0.78 9.7 5.5 2.7 7.9 5.5 1.9 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Sporozoite_P67 PF05642.11 GAX26760.1 - 0.91 7.5 3.7 1.5 6.8 3.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 GAX26760.1 - 0.92 8.8 6.6 2 7.7 6.6 1.5 1 0 0 1 1 1 0 BUD22 Arm PF00514.23 GAX26760.1 - 0.96 9.6 3.8 37 4.5 0.1 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TFIIA PF03153.13 GAX26760.1 - 1.3 9.0 6.5 2.7 7.9 6.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V-ATPase_H_C PF11698.8 GAX26760.1 - 1.4 9.1 11.1 0.037 14.1 0.7 3.8 4 1 1 5 5 4 0 V-ATPase subunit H PPP4R2 PF09184.11 GAX26760.1 - 1.5 8.3 7.8 3.6 7.1 7.8 1.6 1 0 0 1 1 1 0 PPP4R2 YL1 PF05764.13 GAX26760.1 - 2.3 8.3 8.1 4.4 7.4 8.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_C2 PF00648.21 GAX26762.1 - 2.4e-71 240.2 1.9 7.3e-71 238.6 1.9 1.7 1 1 0 1 1 1 1 Calpain family cysteine protease Lipase_GDSL_2 PF13472.6 GAX26763.1 - 0.0021 18.5 0.1 0.0034 17.8 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 GAX26764.1 - 0.0061 17.0 0.2 0.016 15.6 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 GAX26765.1 - 6.2e-05 23.5 0.2 0.00014 22.3 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Hint PF01079.20 GAX26766.1 - 4.9e-14 52.4 0.0 8.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Hint module Neur_chan_memb PF02932.16 GAX26766.1 - 0.024 14.7 0.5 0.038 14.1 0.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleo_P87 PF07267.11 GAX26766.1 - 3.2 6.5 10.0 4.9 5.9 10.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SAPS PF04499.15 GAX26766.1 - 4.2 6.0 10.8 6.1 5.5 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNB PF00773.19 GAX26767.1 - 2.8e-22 79.5 0.0 4.5e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 RNB domain Multi_Drug_Res PF00893.19 GAX26768.1 - 3.6e-12 46.8 5.3 4.7e-12 46.4 5.3 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein Condensin2nSMC PF12422.8 GAX26769.1 - 6e-30 104.4 0.1 1.3e-28 100.1 0.0 3.0 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 GAX26769.1 - 2.9e-05 24.0 3.4 4 7.9 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Adaptin_N PF01602.20 GAX26769.1 - 0.00014 20.6 2.7 0.0034 16.0 0.5 3.3 3 0 0 3 3 3 1 Adaptin N terminal region HEAT_EZ PF13513.6 GAX26769.1 - 0.0075 16.8 8.0 0.039 14.5 0.5 4.1 3 1 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 GAX26769.1 - 0.12 12.8 8.7 3.4 8.1 0.5 4.3 3 1 1 4 4 4 0 HEAT repeats COX5B PF01215.19 GAX26770.1 - 2.4e-05 24.0 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF3984 PF13136.6 GAX26770.1 - 0.15 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) NAC PF01849.18 GAX26770.1 - 0.59 10.1 0.1 0.59 10.1 0.1 2.4 4 0 0 4 4 4 0 NAC domain Mucin PF01456.17 GAX26771.1 - 0.2 11.7 13.7 0.39 10.7 13.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 GAX26771.1 - 0.2 9.7 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tir_receptor_C PF07489.11 GAX26771.1 - 5.8 6.8 8.5 10 6.0 8.5 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Proteasome PF00227.26 GAX26772.1 - 3.2e-22 79.0 0.0 3.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Thioredoxin PF00085.20 GAX26773.1 - 1.1e-26 92.8 0.1 1.3e-26 92.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAX26773.1 - 0.00038 19.9 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAX26773.1 - 0.00053 20.4 0.1 0.003 18.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX26773.1 - 0.0075 16.4 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAX26773.1 - 0.01 15.6 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 GAX26773.1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 GAX26773.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DIM1 PF02966.16 GAX26773.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 NVEALA PF14055.6 GAX26773.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 NVEALA protein FKBP_N PF01346.18 GAX26774.1 - 0.011 16.6 0.0 0.028 15.4 0.0 1.7 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Cupin_7 PF12973.7 GAX26775.1 - 1.8e-05 24.5 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 2 ChrR Cupin-like domain Cupin_2 PF07883.11 GAX26775.1 - 0.0089 15.7 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 Cupin domain DDE_Tnp_1_7 PF13843.6 GAX26777.1 - 1.9e-14 53.7 0.1 1.3e-13 51.1 0.0 2.3 2 1 0 2 2 2 1 Transposase IS4 zf-HC5HC2H PF13771.6 GAX26777.1 - 0.045 14.0 1.9 0.13 12.6 1.9 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAX26777.1 - 0.098 12.8 1.2 0.24 11.5 1.2 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain 7tm_1 PF00001.21 GAX26780.1 - 0.02 14.2 17.0 0.11 11.8 17.0 2.0 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DEAD PF00270.29 GAX26781.1 - 1.6e-49 168.0 0.0 2.7e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX26781.1 - 1.7e-32 112.0 0.0 8.8e-32 109.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX26781.1 - 0.00042 20.3 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX26781.1 - 0.062 12.5 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 GAX26781.1 - 0.24 10.1 0.0 0.77 8.5 0.0 1.8 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 GAX26781.1 - 0.26 10.6 0.0 0.53 9.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Globin PF00042.22 GAX26782.1 - 9.9e-13 48.6 0.0 1.4e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Globin Folate_rec PF03024.14 GAX26783.1 - 1.6e-35 122.5 15.3 1.2e-30 106.7 14.9 2.1 2 0 0 2 2 2 2 Folate receptor family NPC1_N PF16414.5 GAX26783.1 - 0.011 15.3 4.7 0.016 14.8 4.7 1.2 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus ELO PF01151.18 GAX26785.1 - 6.1e-55 186.5 30.2 7.1e-55 186.2 30.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RAMP4 PF06624.12 GAX26785.1 - 0.077 13.1 0.2 0.22 11.6 0.2 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Peptidase_M24 PF00557.24 GAX26786.1 - 5.3e-44 150.4 0.2 6.9e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_S28 PF05577.12 GAX26787.1 - 9.5e-56 189.4 0.0 1.2e-55 189.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Mito_carr PF00153.27 GAX26788.1 - 3.9e-58 193.4 5.1 1.5e-18 66.5 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 GAX26790.1 - 6.9e-31 107.7 1.8 7.7e-31 107.5 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX26790.1 - 2.4e-16 60.2 4.4 2.4e-16 60.2 4.4 3.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase GMC_oxred_N PF00732.19 GAX26792.1 - 2.6e-30 105.8 0.0 1.2e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 GAX26792.1 - 2e-27 96.5 0.0 3.4e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAX26792.1 - 1.2e-05 25.4 0.2 6.9e-05 23.0 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX26792.1 - 0.00016 20.9 0.0 0.0078 15.3 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 GAX26792.1 - 0.004 15.9 0.0 0.0067 15.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FYTT PF07078.11 GAX26792.1 - 0.0059 16.0 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Forty-two-three protein ApbA PF02558.16 GAX26792.1 - 0.01 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 GAX26792.1 - 0.013 14.6 0.1 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAX26792.1 - 0.016 14.5 0.0 0.055 12.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX26792.1 - 0.018 14.6 0.0 0.084 12.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX26792.1 - 0.046 12.8 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAX26792.1 - 0.068 12.4 0.0 9.3 5.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Toxin_29 PF08116.11 GAX26792.1 - 0.13 12.3 0.5 0.84 9.7 0.1 2.2 2 0 0 2 2 2 0 PhTx neurotoxin family FA_hydroxylase PF04116.13 GAX26793.1 - 9e-14 52.0 20.2 9e-14 52.0 20.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DEAD PF00270.29 GAX26794.1 - 7.1e-42 143.1 0.0 1.5e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX26794.1 - 1.9e-31 108.6 0.0 1.2e-30 106.0 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 GAX26794.1 - 2.5e-09 37.3 0.2 5.9e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 GAX26794.1 - 0.002 18.2 0.0 0.0076 16.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAX26794.1 - 0.0063 15.9 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 GAX26794.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 GAX26794.1 - 0.21 11.3 2.2 5.2 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF1658 PF07871.11 GAX26795.1 - 2.7 8.1 5.2 6.9 6.8 5.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1658) UCH PF00443.29 GAX26796.1 - 2.1e-41 142.1 0.1 3.8e-41 141.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX26796.1 - 5.1e-21 75.6 0.5 5.1e-21 75.6 0.5 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAX26796.1 - 2.3e-10 40.6 10.5 2.3e-10 40.6 10.5 2.5 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein NPP PF08384.10 GAX26796.1 - 2.1 8.5 6.1 1.5 8.9 2.3 2.7 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region RPE65 PF03055.15 GAX26797.1 - 1.1e-69 235.9 0.2 1.3e-69 235.6 0.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2575 PF10837.8 GAX26797.1 - 0.18 12.1 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) 4PPT_N PF17837.1 GAX26798.1 - 3.9e-09 36.5 0.0 3.1e-08 33.6 0.0 2.5 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 GAX26798.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Solute_trans_a PF03619.16 GAX26799.1 - 1.8e-83 280.1 16.3 2.7e-83 279.6 16.3 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Orf78 PF06024.12 GAX26799.1 - 0.046 14.0 2.7 0.075 13.3 0.3 2.7 2 0 0 2 2 2 0 Orf78 (ac78) DUF423 PF04241.15 GAX26799.1 - 0.13 12.4 3.2 0.18 12.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF423) SLAC1 PF03595.17 GAX26799.1 - 1.7 7.9 13.0 0.67 9.2 3.3 2.3 2 1 0 2 2 2 0 Voltage-dependent anion channel Cupin_8 PF13621.6 GAX26800.1 - 9.1e-20 71.4 1.3 1.4e-17 64.2 0.6 2.1 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 GAX26800.1 - 6.4e-09 36.2 0.3 3.8e-08 33.7 0.3 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 GAX26800.1 - 1.2e-05 25.0 0.0 3.4e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 GAX26800.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 GAX26800.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Bap31 PF05529.12 GAX26800.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Cupin_8 PF13621.6 GAX26801.1 - 1.7e-20 73.8 0.7 1.3e-17 64.4 0.4 2.1 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 GAX26801.1 - 6.6e-09 36.2 0.3 1.8e-08 34.8 0.3 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 GAX26801.1 - 0.00026 20.6 0.0 0.00099 18.8 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 GAX26801.1 - 0.0099 15.4 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein TPMT PF05724.11 GAX26802.1 - 3.1e-43 148.0 0.4 4.1e-43 147.6 0.4 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 GAX26802.1 - 1.4e-07 32.2 0.0 2.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX26802.1 - 3.1e-07 30.3 0.0 7.8e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX26802.1 - 4.9e-06 27.2 0.0 1.3e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX26802.1 - 5.9e-05 23.6 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX26802.1 - 0.0035 17.2 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX26803.1 - 0.0078 16.9 0.0 0.014 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX26803.1 - 0.041 13.7 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAX26803.1 - 0.042 13.7 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAX26803.1 - 0.19 12.4 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DX PF01666.17 GAX26805.1 - 0.035 14.5 8.1 0.16 12.4 1.0 2.4 2 0 0 2 2 2 0 DX module HMG_box PF00505.19 GAX26807.1 - 2.3e-10 40.7 9.9 1.2e-06 28.9 6.0 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX26807.1 - 8e-08 32.8 10.6 1.4e-06 28.7 10.6 2.3 1 1 0 1 1 1 1 HMG-box domain UCR_Fe-S_N PF10399.9 GAX26807.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal YABBY PF04690.13 GAX26807.1 - 2.8 8.5 8.4 0.61 10.6 1.7 2.9 2 1 1 3 3 3 0 YABBY protein Patatin PF01734.22 GAX26808.1 - 1.3e-10 41.8 0.0 6.3e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase ADH_N PF08240.12 GAX26809.1 - 3.8e-27 94.3 6.5 6.8e-27 93.5 6.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAX26809.1 - 1.7e-18 66.8 0.2 3e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAX26809.1 - 1.4e-05 24.5 0.1 2.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 GAX26809.1 - 8.3e-05 23.7 0.1 0.00021 22.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAX26809.1 - 0.00019 20.8 1.1 0.00029 20.2 1.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 GAX26809.1 - 0.00073 19.8 0.3 0.0034 17.6 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAX26809.1 - 0.0011 19.0 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 GAX26809.1 - 0.0012 18.4 0.3 0.0019 17.7 0.3 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_2 PF03446.15 GAX26809.1 - 0.012 15.8 1.1 0.02 15.0 0.5 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAX26809.1 - 0.095 13.3 0.2 0.19 12.3 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CAP_GLY PF01302.25 GAX26810.1 - 8.8e-17 60.9 2.6 1.5e-16 60.1 2.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 GAX26810.1 - 0.00012 22.5 0.1 0.0015 18.9 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin-like domain Ligase_CoA PF00549.19 GAX26811.1 - 7.5e-23 81.0 0.0 1.2e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 GAX26811.1 - 3.3e-21 75.8 0.4 7.3e-21 74.7 0.4 1.6 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 GAX26811.1 - 1.1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAX26811.1 - 1.1e-05 25.8 0.1 3.4e-05 24.3 0.1 1.8 2 0 0 2 2 2 1 CoA binding domain Glyco_tran_WecB PF03808.13 GAX26811.1 - 0.06 13.3 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family GFO_IDH_MocA PF01408.22 GAX26811.1 - 0.09 13.6 0.0 0.24 12.2 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Jak1_Phl PF17887.1 GAX26812.1 - 0.017 15.1 9.4 0.35 10.8 0.7 2.1 1 1 1 2 2 2 0 Jak1 pleckstrin homology-like domain Usp PF00582.26 GAX26812.1 - 0.042 14.4 0.1 0.042 14.4 0.1 1.8 2 0 0 2 2 2 0 Universal stress protein family DUF3930 PF13067.6 GAX26812.1 - 0.58 10.4 4.2 56 4.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3930) EssA PF10661.9 GAX26812.1 - 0.62 9.9 14.7 0.11 12.3 1.9 2.1 1 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Atg14 PF10186.9 GAX26812.1 - 0.67 9.0 12.8 0.77 8.8 12.8 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Duffy_binding PF05424.11 GAX26812.1 - 8.8 6.3 15.1 3.2e+03 -2.0 15.1 2.2 1 1 0 1 1 1 0 Duffy binding domain PP2C PF00481.21 GAX26813.1 - 5.8e-56 190.0 0.0 8.3e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX26813.1 - 1.5e-05 24.8 0.1 0.00014 21.6 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Heme_oxygenase PF01126.20 GAX26814.1 - 1.4e-57 194.8 0.4 2.8e-57 193.8 0.4 1.5 1 0 0 1 1 1 1 Heme oxygenase Pet20 PF08692.10 GAX26814.1 - 0.038 14.7 0.3 0.13 13.0 0.3 1.9 1 0 0 1 1 1 0 Mitochondrial protein Pet20 V_ATPase_I PF01496.19 GAX26814.1 - 0.04 11.9 1.5 0.055 11.4 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnd3 PF12719.7 GAX26814.1 - 0.066 12.4 2.1 0.12 11.5 2.1 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain zf_CCCH_5 PF18384.1 GAX26814.1 - 1.8 8.7 6.0 0.95 9.6 0.4 3.0 3 0 0 3 3 3 0 Unkempt Zinc finger domain 1 (Znf1) Peptidase_M18 PF02127.15 GAX26815.1 - 3.5e-151 503.9 0.0 4e-151 503.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAX26815.1 - 0.00013 21.2 0.1 0.057 12.4 0.2 2.3 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase YL1 PF05764.13 GAX26816.1 - 0.011 15.8 1.6 0.019 15.1 1.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein PAC1 PF16094.5 GAX26816.1 - 0.093 11.9 1.4 2.5 7.2 0.7 2.1 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Cu2_monoox_C PF03712.15 GAX26817.1 - 1.4e-18 66.9 0.0 3.5e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 GAX26817.1 - 1.9e-11 44.3 0.0 7e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 GAX26817.1 - 3.3e-08 33.8 0.0 9.3e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 DOMON domain EamA PF00892.20 GAX26818.1 - 9.2e-20 71.2 21.2 3e-10 40.4 5.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX26818.1 - 0.025 13.8 5.7 0.019 14.2 4.1 1.5 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport PET117 PF15786.5 GAX26819.1 - 2.7e-10 40.3 2.1 3.4e-10 40.1 2.1 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial HSF_DNA-bind PF00447.17 GAX26820.1 - 1.8e-13 50.9 0.0 3.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 GAX26821.1 - 3.2e-12 46.9 0.0 5.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Fez1 PF06818.15 GAX26822.1 - 0.018 15.5 0.5 0.027 14.9 0.5 1.2 1 0 0 1 1 1 0 Fez1 Cpn60_TCP1 PF00118.24 GAX26824.1 - 6.2e-157 523.1 5.8 7.1e-157 523.0 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Adeno_E1A PF02703.14 GAX26824.1 - 0.031 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Early E1A protein SIR2 PF02146.17 GAX26825.1 - 8.9e-42 143.0 0.1 2.6e-27 95.9 0.0 2.3 2 0 0 2 2 2 2 Sir2 family Prok-RING_1 PF14446.6 GAX26825.1 - 0.0068 16.3 0.7 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 TPP_enzyme_M PF00205.22 GAX26825.1 - 0.007 16.1 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain zinc_ribbon_9 PF14369.6 GAX26825.1 - 0.015 15.6 0.4 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon Lar_restr_allev PF14354.6 GAX26825.1 - 0.73 10.3 3.2 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar Tmemb_cc2 PF10267.9 GAX26826.1 - 3.4 6.7 6.3 4.4 6.3 6.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein NCA2 PF08637.10 GAX26827.1 - 1.5e-18 67.0 0.1 2.4e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 RCS1 PF07326.11 GAX26827.1 - 0.025 14.5 3.1 0.047 13.6 3.1 1.4 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 Nop PF01798.18 GAX26827.1 - 0.28 10.6 2.2 0.45 9.9 2.2 1.2 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin PRCC PF10253.9 GAX26828.1 - 0.16 12.7 3.4 0.5 11.1 3.4 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3299 PF11736.8 GAX26828.1 - 3.7 7.6 6.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) FH2 PF02181.23 GAX26829.1 - 5e-71 239.8 20.0 2.2e-69 234.4 20.0 2.6 1 1 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 GAX26829.1 - 7.4e-13 49.2 29.4 2.7e-09 37.6 0.1 8.2 5 3 0 5 5 5 2 Subunit CCDC53 of WASH complex DUF202 PF02656.15 GAX26830.1 - 0.22 12.0 15.4 0.36 11.3 2.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) APA3_viroporin PF11289.8 GAX26830.1 - 1.3 8.5 6.2 1.9 8.0 6.2 1.3 1 0 0 1 1 1 0 Coronavirus accessory protein 3a TatC PF00902.18 GAX26830.1 - 3.1 7.6 14.2 2.1 8.1 12.7 1.5 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) RNase_PH PF01138.21 GAX26833.1 - 1.2e-22 80.9 2.5 1.3e-22 80.7 0.5 2.0 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAX26833.1 - 0.003 17.6 0.1 0.005 16.8 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ACT_7 PF13840.6 GAX26834.1 - 5.8e-21 74.1 0.0 1.1e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 GAX26834.1 - 0.031 14.0 0.0 0.072 12.9 0.0 1.7 1 1 0 1 1 1 0 ACT domain ATPgrasp_ST PF14397.6 GAX26836.1 - 2.9e-09 36.6 0.0 2.6e-08 33.5 0.0 2.2 1 1 1 2 2 2 1 Sugar-transfer associated ATP-grasp zf-NOSIP PF15906.5 GAX26837.1 - 1.3e-08 34.9 0.2 6.9e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein GPCR_chapero_1 PF11904.8 GAX26837.1 - 0.008 15.6 0.3 0.012 15.1 0.3 1.3 1 0 0 1 1 1 1 GPCR-chaperone NEXCaM_BD PF16644.5 GAX26837.1 - 0.03 14.5 2.6 0.33 11.2 0.1 2.4 2 0 0 2 2 2 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Rtf2 PF04641.12 GAX26837.1 - 0.36 10.2 0.0 0.36 10.2 0.0 2.3 2 1 1 3 3 3 0 Rtf2 RING-finger Telomere_reg-2 PF10193.9 GAX26839.1 - 1.2e-19 70.7 0.2 9.7e-19 67.8 0.1 2.7 2 0 0 2 2 2 1 Telomere length regulation protein DUF4042 PF13251.6 GAX26839.1 - 0.088 12.5 0.1 1.5 8.5 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) UCH PF00443.29 GAX26841.1 - 1.8e-41 142.4 0.0 3.7e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX26841.1 - 2.4e-21 76.7 0.1 4.1e-17 62.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAX26842.1 - 4.7e-11 42.8 5.4 4.7e-11 42.8 5.4 2.3 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 GAX26842.1 - 9.9e-08 32.1 0.0 3e-07 30.6 0.0 1.8 2 0 0 2 2 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 GAX26842.1 - 3.5e-07 30.5 9.5 3.5e-07 30.5 9.5 2.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX26842.1 - 9.5e-06 25.4 9.9 9.5e-06 25.4 9.9 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX26842.1 - 1.2e-05 25.1 7.3 1.2e-05 25.1 7.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAX26842.1 - 1.3e-05 24.8 7.8 1.3e-05 24.8 7.8 2.2 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAX26842.1 - 4.2e-05 23.7 7.7 4.2e-05 23.7 7.7 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX26842.1 - 5.8e-05 22.9 8.3 5.8e-05 22.9 8.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX26842.1 - 0.00054 19.9 1.7 0.00054 19.9 1.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger HAUS-augmin3 PF14932.6 GAX26842.1 - 0.0088 15.7 12.1 0.017 14.8 12.1 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 AAA_23 PF13476.6 GAX26842.1 - 0.015 15.8 6.0 0.024 15.2 6.0 1.2 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.6 GAX26842.1 - 0.023 14.6 5.0 0.023 14.6 5.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BLOC1_2 PF10046.9 GAX26842.1 - 0.063 13.6 4.1 0.2 12.0 4.1 1.9 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.13 GAX26842.1 - 0.084 13.0 7.6 0.2 11.7 7.6 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PCRF PF03462.18 GAX26842.1 - 0.1 12.5 4.9 0.19 11.5 4.9 1.5 1 0 0 1 1 1 0 PCRF domain DUF3450 PF11932.8 GAX26842.1 - 0.12 11.7 12.8 0.22 10.8 12.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 GAX26842.1 - 0.13 12.8 14.4 0.31 11.6 14.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 GAX26842.1 - 0.19 12.0 10.2 0.33 11.2 9.8 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SHE3 PF17078.5 GAX26842.1 - 0.27 10.9 16.0 0.052 13.3 9.0 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Ly49 PF08391.10 GAX26842.1 - 0.27 11.6 5.3 0.78 10.1 5.3 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region FapA PF03961.13 GAX26842.1 - 0.41 9.2 5.2 0.58 8.7 5.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ZapB PF06005.12 GAX26842.1 - 0.51 10.8 20.2 0.1 13.0 10.9 2.9 1 1 1 2 2 2 0 Cell division protein ZapB PHD PF00628.29 GAX26842.1 - 0.82 9.6 18.4 0.84 9.6 4.2 2.7 2 0 0 2 2 2 0 PHD-finger zf-ANAPC11 PF12861.7 GAX26842.1 - 0.91 9.6 10.4 0.086 12.9 5.4 1.9 1 1 1 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1664 PF07889.12 GAX26842.1 - 0.99 9.5 3.8 2.5 8.1 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 GAX26842.1 - 1 7.2 7.4 1.4 6.7 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.6 GAX26842.1 - 1.2 9.4 10.6 0.068 13.5 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ApoLp-III PF07464.11 GAX26842.1 - 1.5 8.9 9.7 0.6 10.2 6.4 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Cep57_MT_bd PF06657.13 GAX26842.1 - 1.5 9.3 12.0 1.3 9.5 6.2 2.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 GAX26842.1 - 1.7 9.3 10.0 1.9 9.2 5.9 2.7 2 0 0 2 2 2 0 Initiation control protein YabA DUF2400 PF09674.10 GAX26842.1 - 1.8 8.5 6.3 2.4 8.1 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Exonuc_VII_L PF02601.15 GAX26842.1 - 2.6 7.5 11.6 4.5 6.8 11.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PHF5 PF03660.14 GAX26842.1 - 4 7.7 11.0 1.8 8.8 7.6 2.1 1 1 1 2 2 2 0 PHF5-like protein Uso1_p115_C PF04871.13 GAX26842.1 - 5.8 7.3 13.9 4.6 7.6 11.4 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ndc1_Nup PF09531.10 GAX26843.1 - 1 8.0 4.0 1.1 7.8 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 GAX26843.1 - 3 7.0 5.2 3.8 6.6 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 GAX26843.1 - 6.3 5.5 19.2 12 4.5 19.2 1.5 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 GAX26843.1 - 7.3 5.8 8.2 11 5.2 8.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Mito_carr PF00153.27 GAX26844.1 - 7.8e-21 73.8 0.2 5.7e-09 35.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-binding PF00249.31 GAX26845.1 - 3.4e-54 180.8 16.3 1.8e-18 66.4 0.8 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX26845.1 - 2.6e-40 136.5 7.3 3.3e-17 62.5 1.3 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 GAX26845.1 - 1.3e-08 34.9 0.0 0.2 11.7 0.0 3.3 2 1 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 GAX26845.1 - 0.00014 21.7 0.1 0.032 14.1 0.0 2.5 2 0 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 GAX26845.1 - 0.00029 21.1 2.8 1.2 9.5 0.0 3.3 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GAX26845.1 - 0.035 14.5 12.1 4.1 7.9 1.2 4.4 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 GAX26845.1 - 0.044 13.9 12.0 1.4 9.1 0.7 3.2 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 GAX26845.1 - 0.17 12.1 1.5 24 5.2 0.0 3.6 2 1 1 3 3 3 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 GAX26845.1 - 0.23 11.7 1.4 2.3 8.5 0.1 2.7 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Pro_isomerase PF00160.21 GAX26848.1 - 7.1e-06 26.4 0.0 1.2e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_C9 PF01707.16 GAX26848.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C9 FANCL_C PF11793.8 GAX26849.1 - 0.15 12.3 1.6 0.24 11.6 0.8 1.7 1 1 1 2 2 2 0 FANCL C-terminal domain DNA_pol_A_exo1 PF01612.20 GAX26852.1 - 3.2e-16 59.5 0.3 5.6e-16 58.8 0.3 1.4 1 0 0 1 1 1 1 3'-5' exonuclease tRNA_edit PF04073.15 GAX26852.1 - 3.4e-14 53.0 0.0 6.3e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HBM PF16591.5 GAX26852.1 - 0.079 12.4 0.3 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain Form_Nir_trans PF01226.17 GAX26853.1 - 4.7e-70 235.6 17.0 5.4e-70 235.4 17.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2583 PF10762.9 GAX26853.1 - 0.013 15.9 0.0 0.013 15.9 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2583) Ceramidase PF05875.12 GAX26853.1 - 0.62 9.4 5.2 0.3 10.5 3.1 1.5 2 0 0 2 2 2 0 Ceramidase Xin PF08043.12 GAX26855.1 - 0.0051 16.4 0.2 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 Xin repeat PCRF PF03462.18 GAX26856.1 - 9.5e-69 231.1 0.4 2.8e-68 229.6 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAX26856.1 - 7.3e-38 129.1 1.1 7.3e-38 129.1 1.1 1.9 2 0 0 2 2 2 1 RF-1 domain MCU PF04678.13 GAX26856.1 - 0.099 12.7 2.1 0.35 10.9 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter ABC_tran_CTD PF16326.5 GAX26856.1 - 5.2 7.4 15.7 15 6.0 0.0 3.7 3 1 0 4 4 4 0 ABC transporter C-terminal domain Glyco_hydro_30 PF02055.16 GAX26860.1 - 6.7e-57 193.0 0.0 1.5e-56 191.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 GAX26860.1 - 1.2e-07 31.9 0.0 7.5e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain FhuF PF06276.12 GAX26860.1 - 0.0035 17.8 0.1 3.2 8.1 0.0 3.4 3 0 0 3 3 3 1 Ferric iron reductase FhuF-like transporter Glyco_hydro_59 PF02057.15 GAX26860.1 - 0.005 16.1 1.3 0.019 14.2 1.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Ricin_B_lectin PF00652.22 GAX26860.1 - 0.02 15.1 0.1 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain MarB PF13999.6 GAX26860.1 - 0.09 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 MarB protein Sulfotransfer_3 PF13469.6 GAX26861.1 - 3.2e-09 37.5 1.3 1.1e-08 35.8 1.3 1.8 1 1 0 1 1 1 1 Sulfotransferase family Glycos_transf_2 PF00535.26 GAX26861.1 - 5.8e-09 36.0 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Sulfotransfer_1 PF00685.27 GAX26861.1 - 0.001 18.6 0.2 0.0029 17.1 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_tranf_2_3 PF13641.6 GAX26861.1 - 0.0028 17.6 0.1 0.011 15.6 0.1 2.0 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Cupin_8 PF13621.6 GAX26862.1 - 7.9e-18 65.1 3.9 5e-17 62.5 1.2 2.6 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 GAX26862.1 - 3.9e-10 40.1 0.6 3.6e-09 37.1 0.2 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase F-box-like PF12937.7 GAX26862.1 - 2.8e-06 27.1 2.5 4.2e-06 26.6 0.2 2.3 2 0 0 2 2 2 1 F-box-like Cupin_4 PF08007.12 GAX26862.1 - 4e-05 23.3 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein F-box PF00646.33 GAX26862.1 - 0.069 13.1 1.0 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 F-box domain Cupin_1 PF00190.22 GAX26862.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 1 0 1 1 1 0 Cupin Elongin_A PF06881.11 GAX26862.1 - 0.44 11.1 1.6 0.86 10.2 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Methyltrans_SAM PF10672.9 GAX26863.1 - 1.6e-20 73.5 0.0 2.6e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 GAX26863.1 - 2.3e-07 30.7 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 GAX26863.1 - 0.0018 17.8 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MBOAT PF03062.19 GAX26864.1 - 1.1e-27 97.4 8.7 1.1e-27 97.4 8.7 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PsbX PF06596.11 GAX26864.1 - 0.77 9.8 2.5 1 9.4 0.2 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Cyclin_N PF00134.23 GAX26866.1 - 2.4e-49 166.3 2.7 9.8e-46 154.6 1.4 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX26866.1 - 1.5e-25 89.6 0.0 3.3e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain MFS_1 PF07690.16 GAX26867.1 - 2.9e-37 128.4 54.3 6.3e-29 101.0 38.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX26867.1 - 3.7e-36 125.0 12.3 5.5e-36 124.4 12.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter His_Phos_1 PF00300.22 GAX26868.1 - 4.9e-35 121.0 0.0 5.8e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HA PF03457.14 GAX26869.1 - 1.6e-10 41.1 0.1 3.7e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain EamA PF00892.20 GAX26871.1 - 4e-20 72.4 33.5 5.8e-12 46.0 9.8 3.4 4 0 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.15 GAX26871.1 - 0.009 15.2 0.6 0.36 10.0 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter MerC PF03203.14 GAX26871.1 - 0.22 12.0 8.2 0.21 12.0 3.0 3.0 1 1 1 2 2 2 0 MerC mercury resistance protein SelK_SelG PF10961.8 GAX26875.1 - 1.6e-11 44.6 0.7 2e-11 44.3 0.7 1.1 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Nuc_sug_transp PF04142.15 GAX26876.1 - 2.8e-55 187.7 10.9 3.4e-55 187.4 10.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAX26876.1 - 3.4e-07 29.8 5.0 3.4e-07 29.8 5.0 2.5 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.20 GAX26876.1 - 8.8e-05 22.7 19.4 0.00019 21.6 2.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family WBS28 PF15164.6 GAX26876.1 - 0.02 14.2 0.2 0.035 13.4 0.2 1.5 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue HEAT_EZ PF13513.6 GAX26877.1 - 1.9e-06 28.2 22.1 0.14 12.7 0.4 8.7 7 2 3 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.6 GAX26877.1 - 1.6e-05 25.2 4.7 0.56 10.6 0.0 5.7 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 GAX26877.1 - 0.00017 21.5 12.9 0.42 11.0 0.3 6.7 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 GAX26877.1 - 0.00036 19.2 0.9 0.87 8.1 0.0 3.2 3 1 0 3 3 3 2 Adaptin N terminal region RIX1 PF08167.12 GAX26877.1 - 0.0019 17.9 0.8 0.13 12.0 0.2 3.1 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 GAX26877.1 - 0.12 13.0 0.1 0.6 10.7 0.0 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Importin_rep_4 PF18808.1 GAX26877.1 - 0.76 10.1 8.7 69 3.8 4.8 3.7 3 0 0 3 3 3 0 Importin repeat DUF2457 PF10446.9 GAX26877.1 - 2.1 7.4 8.9 3.1 6.9 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 GAX26877.1 - 2.5 7.3 10.0 4.1 6.6 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein Bestrophin PF01062.21 GAX26878.1 - 3.1e-45 154.8 0.3 4.1e-45 154.4 0.3 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel hGDE_N PF14699.6 GAX26878.1 - 0.0029 17.7 0.2 0.0071 16.5 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme SAC3_GANP PF03399.16 GAX26879.1 - 1e-19 71.1 6.8 2.6e-18 66.4 6.8 2.3 1 1 0 1 1 1 1 SAC3/GANP family FATC PF02260.20 GAX26879.1 - 0.0098 15.7 0.6 0.025 14.4 0.3 1.8 2 0 0 2 2 2 1 FATC domain DLH PF01738.18 GAX26880.1 - 2.2e-17 63.3 0.0 3.1e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX26880.1 - 0.011 15.2 0.0 2.4 7.5 0.0 2.4 1 1 1 2 2 2 0 Prolyl oligopeptidase family His_Phos_1 PF00300.22 GAX26881.1 - 3.4e-06 26.9 0.0 8.9e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ATP-synt PF00231.19 GAX26882.1 - 1.8e-88 296.9 0.3 2.1e-88 296.7 0.3 1.1 1 0 0 1 1 1 1 ATP synthase DUF5557 PF17712.1 GAX26882.1 - 0.051 13.5 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5557) TP_methylase PF00590.20 GAX26883.1 - 1.1e-36 126.8 0.0 1.4e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1858 PF08984.11 GAX26883.1 - 0.034 14.3 0.0 0.088 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) DUF4670 PF15709.5 GAX26884.1 - 0.081 12.2 5.5 0.13 11.6 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) AIF_C PF14721.6 GAX26884.1 - 0.16 12.3 1.3 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cyclin_N PF00134.23 GAX26885.1 - 1.2e-44 151.1 0.9 5e-41 139.4 0.3 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX26885.1 - 4.6e-18 65.4 0.0 9.8e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Gag_p19 PF02228.16 GAX26885.1 - 0.14 12.6 0.0 0.53 10.7 0.0 1.9 2 0 0 2 2 2 0 Major core protein p19 DnaJ PF00226.31 GAX26886.1 - 5.2e-05 23.3 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 GAX26886.1 - 0.0073 16.3 0.0 0.0073 16.3 0.0 1.7 2 0 0 2 2 2 1 Pam16 DUF4539 PF15072.6 GAX26887.1 - 0.00027 20.9 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) RisS_PPD PF16524.5 GAX26888.1 - 0.076 13.3 0.5 0.098 12.9 0.5 1.3 1 1 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS Spc7 PF08317.11 GAX26889.1 - 0.00049 19.1 11.9 0.00056 18.9 10.7 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein DivIC PF04977.15 GAX26889.1 - 0.71 9.7 20.3 0.65 9.8 0.6 3.9 4 0 0 4 4 4 0 Septum formation initiator Exonuc_VII_L PF02601.15 GAX26889.1 - 1.4 8.4 6.8 2.3 7.7 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 GAX26889.1 - 2 8.9 23.6 1.6 9.3 21.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 GAX26889.1 - 3.6 7.7 22.6 0.13 12.4 14.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 GAX26889.1 - 9.4 6.1 14.7 7.4 6.5 5.3 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain AAA_assoc_C PF09821.9 GAX26890.1 - 0.57 10.7 5.4 1.5 9.4 5.4 1.7 1 0 0 1 1 1 0 C-terminal AAA-associated domain DUF1640 PF07798.11 GAX26891.1 - 0.73 9.9 9.3 1.2 9.2 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) CDC27 PF09507.10 GAX26891.1 - 3.5 6.9 27.2 0.078 12.4 19.8 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SnoaL_3 PF13474.6 GAX26892.1 - 8.2e-18 64.8 0.8 8.2e-18 64.8 0.8 1.9 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 GAX26892.1 - 3.8e-07 30.5 0.4 8.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) UVR PF02151.19 GAX26892.1 - 1.4e-05 24.6 3.6 3.8e-05 23.3 3.6 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif SnoaL_4 PF13577.6 GAX26892.1 - 0.0068 16.5 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 GAX26892.1 - 0.013 16.1 0.0 0.039 14.6 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain RapH_N PF18801.1 GAX26892.1 - 0.058 13.5 0.9 0.15 12.1 0.9 1.7 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal ArgJ PF01960.18 GAX26893.1 - 1.5e-103 346.5 0.0 1.8e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Thioredoxin PF00085.20 GAX26894.1 - 5.2e-20 71.4 0.0 6.6e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX26894.1 - 4.2e-05 24.0 0.1 0.00012 22.5 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAX26894.1 - 0.00017 21.3 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 GAX26894.1 - 0.0017 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAX26894.1 - 0.0043 17.0 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.11 GAX26894.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 GAX26894.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.6 GAX26894.1 - 0.055 13.6 0.1 1.6 8.8 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 GAX26894.1 - 0.11 12.8 0.2 1.5 9.1 0.2 2.3 2 1 0 2 2 2 0 Glutaredoxin DUF713 PF05218.14 GAX26894.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) TerC PF03741.16 GAX26895.1 - 6.2e-50 169.4 3.8 1.1e-49 168.6 3.8 1.4 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF475 PF04332.15 GAX26895.1 - 0.012 15.4 3.1 0.016 15.0 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF475) RIO1 PF01163.22 GAX26896.1 - 6.8e-50 169.3 0.0 1.9e-37 128.7 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 GAX26896.1 - 9.9e-05 21.3 0.1 9.9e-05 21.3 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAX26896.1 - 0.057 13.3 1.3 0.77 9.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 GAX26897.1 - 2.2e-11 43.9 11.6 4.7e-11 42.8 11.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX26897.1 - 3.8e-07 29.7 3.5 1e-06 28.3 3.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX26897.1 - 6.8e-07 29.0 9.3 1.7e-06 27.7 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAX26897.1 - 1.7e-05 24.9 5.1 0.0009 19.4 7.2 2.4 1 1 1 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.7 GAX26897.1 - 0.00013 22.2 16.9 0.00017 21.8 13.8 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX26897.1 - 0.00093 19.0 9.5 0.00093 19.0 9.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX26897.1 - 0.0014 18.6 2.9 0.0031 17.5 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX26897.1 - 0.043 13.9 9.7 0.12 12.4 9.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger TMEM52 PF14979.6 GAX26897.1 - 0.055 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Transmembrane 52 zf-C3HC4_3 PF13920.6 GAX26897.1 - 0.065 13.1 8.4 0.039 13.8 5.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 GAX26897.1 - 0.093 12.9 3.3 0.093 12.9 0.9 2.2 2 1 0 2 2 2 0 PHD-zinc-finger like domain RINGv PF12906.7 GAX26897.1 - 0.24 11.5 9.9 0.46 10.6 9.9 1.5 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 GAX26897.1 - 0.34 10.8 4.3 0.89 9.4 4.3 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 GAX26897.1 - 6.6 6.8 16.3 0.087 12.8 8.1 2.2 3 0 0 3 3 3 0 zinc-RING finger domain KH_6 PF15985.5 GAX26898.1 - 5.3e-13 49.1 0.0 9.4e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 GAX26898.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain UNC-50 PF05216.13 GAX26899.1 - 4.8e-71 238.8 16.6 5.5e-71 238.6 16.6 1.0 1 0 0 1 1 1 1 UNC-50 family Phage_holin_3_6 PF07332.11 GAX26899.1 - 0.012 15.6 3.1 0.012 15.6 3.1 2.9 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4335 PF14233.6 GAX26899.1 - 0.059 13.3 0.1 0.098 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) CrgA PF06781.12 GAX26899.1 - 0.068 13.2 0.2 0.068 13.2 0.2 2.0 2 0 0 2 2 2 0 Cell division protein CrgA Sulfate_transp PF00916.20 GAX26901.1 - 1e-22 80.5 17.7 1.6e-22 79.9 17.7 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 GAX26901.1 - 2.9e-07 30.5 0.0 3.9e-06 26.8 0.0 2.8 2 1 1 3 3 3 1 Cyclic nucleotide-binding domain STAS PF01740.21 GAX26901.1 - 0.0012 18.4 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain AAA PF00004.29 GAX26902.1 - 7.9e-53 178.4 0.1 6.5e-38 130.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX26902.1 - 1e-08 35.8 0.0 0.00067 20.1 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 GAX26902.1 - 1.8e-08 34.1 0.0 4.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 GAX26902.1 - 5.6e-08 32.4 0.2 0.001 18.4 0.1 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 GAX26902.1 - 1.1e-07 32.2 3.6 0.0016 18.6 0.1 4.0 4 0 0 4 4 4 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAX26902.1 - 2.9e-07 30.8 1.1 0.018 15.3 0.4 3.8 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.12 GAX26902.1 - 1e-05 25.4 0.2 0.022 14.5 0.0 3.2 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAX26902.1 - 1.8e-05 24.8 0.1 0.0013 18.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 GAX26902.1 - 2.2e-05 23.7 0.0 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase PF06745.13 GAX26902.1 - 4.3e-05 23.0 0.5 0.013 14.9 0.0 3.1 3 0 0 3 3 3 1 KaiC RNA_helicase PF00910.22 GAX26902.1 - 4.8e-05 23.7 0.0 0.03 14.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 GAX26902.1 - 0.00025 21.1 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 GAX26902.1 - 0.00027 20.7 0.3 0.67 9.6 0.0 2.7 3 0 0 3 3 3 2 Sigma-54 interaction domain TniB PF05621.11 GAX26902.1 - 0.00032 20.1 0.2 1.1 8.7 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 GAX26902.1 - 0.00051 19.6 0.1 0.1 12.1 0.0 2.9 2 1 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAX26902.1 - 0.00083 18.8 0.1 0.012 15.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 GAX26902.1 - 0.0011 18.3 0.1 0.28 10.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 GAX26902.1 - 0.0016 18.4 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GAX26902.1 - 0.0022 17.8 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein CDC48_N PF02359.18 GAX26902.1 - 0.0023 18.1 0.0 0.045 13.9 0.0 3.2 3 1 0 3 3 2 1 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.12 GAX26902.1 - 0.0042 17.0 0.7 0.43 10.5 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 GAX26902.1 - 0.0045 17.2 0.0 0.45 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX26902.1 - 0.0048 16.5 0.3 1.8 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX26902.1 - 0.0053 16.5 0.0 0.25 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX26902.1 - 0.0065 17.0 0.0 0.35 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GAX26902.1 - 0.0088 15.5 0.0 3.6 7.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein ATPase_2 PF01637.18 GAX26902.1 - 0.011 15.7 0.1 0.36 10.7 0.0 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 GAX26902.1 - 0.012 16.1 0.2 0.75 10.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAX26902.1 - 0.02 14.1 0.0 5.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin CDC48_2 PF02933.17 GAX26902.1 - 0.027 14.2 0.2 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Rad17 PF03215.15 GAX26902.1 - 0.028 14.3 0.0 0.27 11.1 0.0 2.5 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_3 PF07726.11 GAX26902.1 - 0.028 14.3 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IPT PF01745.16 GAX26902.1 - 0.11 11.9 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.9 GAX26902.1 - 0.12 11.5 0.2 3.9 6.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 GAX26902.1 - 0.17 12.2 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Tugs PF17840.1 GAX26902.1 - 0.17 12.1 0.0 0.72 10.1 0.0 2.2 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain AAA_19 PF13245.6 GAX26902.1 - 3.4 8.0 4.9 2.7 8.3 0.0 3.1 4 1 0 4 4 2 0 AAA domain QIL1 PF15884.5 GAX26903.1 - 0.12 13.0 1.1 8.9 7.0 0.1 3.1 2 2 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 LPD34 PF18852.1 GAX26903.1 - 0.41 10.2 3.6 2.2 7.8 2.0 2.2 1 1 1 2 2 2 0 Large polyvalent protein associated domain 34 MCPVI PF02993.14 GAX26903.1 - 1.2 8.9 7.4 0.23 11.2 2.4 1.9 1 1 1 2 2 2 0 Minor capsid protein VI DEAD PF00270.29 GAX26904.1 - 2.2e-49 167.6 0.1 7.2e-49 165.9 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX26904.1 - 3.2e-24 85.4 0.0 4.6e-23 81.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAX26904.1 - 1.1e-16 60.8 0.2 2.3e-16 59.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SecA_DEAD PF07517.14 GAX26904.1 - 0.0028 17.0 0.2 0.0062 15.9 0.1 1.6 2 0 0 2 2 2 1 SecA DEAD-like domain ERCC3_RAD25_C PF16203.5 GAX26904.1 - 0.0081 15.4 0.0 0.0081 15.4 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 GAX26904.1 - 0.017 14.9 0.1 0.35 10.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain AMP-binding PF00501.28 GAX26905.1 - 1.1e-07 30.8 0.0 1.5e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme S_4TM PF18159.1 GAX26905.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Acetyltransf_1 PF00583.25 GAX26906.1 - 7.9e-14 51.9 0.0 1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX26906.1 - 2.3e-12 46.9 0.0 2.8e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX26906.1 - 5.2e-11 42.8 0.0 7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX26906.1 - 5.1e-08 32.8 0.0 7.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAX26906.1 - 2.2e-05 25.1 0.0 2.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX26906.1 - 0.00053 20.1 0.1 0.00075 19.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAX26906.1 - 0.0014 18.2 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_13 PF13880.6 GAX26906.1 - 0.0029 17.6 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase PanZ PF12568.8 GAX26906.1 - 0.015 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_8 PF13523.6 GAX26906.1 - 0.025 14.2 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX26906.1 - 0.03 14.5 0.0 0.082 13.0 0.0 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 GAX26906.1 - 0.069 12.7 0.1 0.097 12.2 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase UCR_14kD PF02271.16 GAX26907.1 - 2.2e-12 46.8 0.1 2.4e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit EMP70 PF02990.16 GAX26908.1 - 8.3e-173 575.8 0.8 3e-172 573.9 0.8 1.8 1 1 0 1 1 1 1 Endomembrane protein 70 WD40 PF00400.32 GAX26909.1 - 1.2e-17 64.0 4.3 4.5e-07 30.5 0.4 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX26909.1 - 0.032 14.5 0.0 8.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TrmO PF01980.16 GAX26910.1 - 1.2e-35 122.3 0.0 2.6e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 GAX26910.1 - 9.5e-05 22.4 0.1 0.0004 20.4 0.0 2.2 2 1 0 2 2 2 1 TrmO C-terminal domain TPR_12 PF13424.6 GAX26911.1 - 2.7e-07 30.8 10.1 0.00074 19.8 1.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAX26911.1 - 0.0014 18.4 6.9 0.28 11.1 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX26911.1 - 0.0029 17.6 8.2 0.24 11.6 0.1 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX26911.1 - 0.027 15.1 8.3 2.3 8.9 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX26911.1 - 0.14 11.9 4.7 16 5.2 0.0 4.2 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 GAX26911.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SelR PF01641.18 GAX26912.1 - 4.3e-37 126.9 0.0 5.8e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 SelR domain DNA_RNApol_7kD PF03604.13 GAX26912.1 - 0.037 13.7 2.8 3.2 7.5 0.1 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit GcrA PF07750.11 GAX26912.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 GcrA cell cycle regulator MINDY_DUB PF04424.13 GAX26913.1 - 1.5e-24 86.3 0.1 6.1e-24 84.3 0.0 2.0 2 0 0 2 2 2 1 MINDY deubiquitinase UIM PF02809.20 GAX26913.1 - 2.2 8.4 7.5 0.5 10.4 1.3 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif AMP-binding PF00501.28 GAX26914.1 - 6.5e-47 160.1 0.0 7.7e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAX26914.1 - 5.9e-14 52.8 0.0 1.2e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YGGT PF02325.17 GAX26915.1 - 1e-18 67.5 4.6 1.7e-18 66.8 4.6 1.4 1 0 0 1 1 1 1 YGGT family Diphthami_syn_2 PF01902.17 GAX26916.1 - 2.6e-25 89.2 0.0 6.6e-25 87.9 0.0 1.7 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 GAX26916.1 - 3.7e-21 75.4 0.1 2.4e-10 40.5 0.0 3.4 3 0 0 3 3 3 2 Endoribonuclease L-PSP CH_2 PF06294.11 GAX26916.1 - 0.045 13.9 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 CH-like domain in sperm protein Glyco_transf_10 PF00852.19 GAX26917.1 - 5.3e-21 75.1 1.3 1.1e-20 74.1 1.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Endopep_inhib PF16800.5 GAX26917.1 - 0.06 13.3 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor EMP24_GP25L PF01105.24 GAX26920.1 - 1.1e-23 84.2 0.6 2.9e-23 82.8 0.6 1.8 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_M18 PF02127.15 GAX26922.1 - 1.8e-111 373.0 0.0 2.1e-111 372.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAX26922.1 - 0.0059 15.7 0.0 2.3 7.2 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase SRP54 PF00448.22 GAX26923.1 - 3e-05 23.7 0.2 6.6e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAX26923.1 - 4.1e-05 24.0 0.3 0.00028 21.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 GAX26923.1 - 0.00019 21.2 0.0 0.00057 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 GAX26923.1 - 0.0021 17.9 0.2 0.0046 16.9 0.2 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase 6PF2K PF01591.18 GAX26923.1 - 0.0025 17.2 0.0 0.0073 15.6 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Rad17 PF03215.15 GAX26923.1 - 0.0037 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain TetR_C_21 PF17926.1 GAX26923.1 - 0.0041 17.3 2.0 2.6 8.2 0.1 2.8 3 0 0 3 3 2 2 Tetracyclin repressor-like, C-terminal domain AAA_33 PF13671.6 GAX26923.1 - 0.0056 16.8 1.2 0.032 14.4 0.1 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GAX26923.1 - 0.009 16.3 0.1 0.025 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAX26923.1 - 0.02 15.3 0.1 0.08 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 GAX26923.1 - 0.024 14.7 0.1 0.066 13.3 0.0 1.7 2 0 0 2 2 2 0 Torsin MobB PF03205.14 GAX26923.1 - 0.03 14.2 0.4 0.082 12.8 0.4 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 GAX26923.1 - 0.034 13.4 0.0 0.44 9.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin PPK2 PF03976.14 GAX26923.1 - 0.037 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) MeaB PF03308.16 GAX26923.1 - 0.037 13.0 0.1 0.071 12.1 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 GAX26923.1 - 0.1 12.2 0.3 0.44 10.2 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 GAX26923.1 - 0.15 12.6 0.0 0.4 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF5505 PF17610.2 GAX26923.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) NTPase_1 PF03266.15 GAX26923.1 - 0.25 11.2 1.3 0.51 10.2 0.4 1.9 2 0 0 2 2 2 0 NTPase Ploopntkinase2 PF18747.1 GAX26923.1 - 0.3 10.3 1.1 0.81 8.9 1.0 1.8 1 1 0 1 1 1 0 P-loop Nucleotide Kinase2 DNA_pol_A_exoN PF18305.1 GAX26924.1 - 0.23 11.8 3.3 0.26 11.6 0.2 2.5 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain Band_3_cyto PF07565.13 GAX26924.1 - 1.6 8.4 7.7 0.1 12.4 0.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4407 PF14362.6 GAX26924.1 - 8.5 5.6 9.4 1.4 8.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CoaE PF01121.20 GAX26925.1 - 1e-34 119.7 0.0 3.4e-28 98.5 0.0 2.9 4 0 0 4 4 4 2 Dephospho-CoA kinase AAA_18 PF13238.6 GAX26925.1 - 0.0023 18.5 0.2 3.8 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RRP14 PF15459.6 GAX26926.1 - 0.057 14.0 1.5 0.057 14.0 1.5 2.4 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 DnaJ PF00226.31 GAX26927.1 - 3.4e-10 39.9 0.0 8.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain FPN1 PF06963.12 GAX26929.1 - 4.6e-88 295.7 18.9 1e-87 294.5 18.9 1.5 1 1 0 1 1 1 1 Ferroportin1 (FPN1) Nepo_coat_N PF03689.15 GAX26929.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Patched PF02460.18 GAX26930.1 - 7e-90 302.3 16.4 9.3e-90 301.9 16.4 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 GAX26930.1 - 3.8e-37 127.5 6.5 3.8e-37 127.5 6.5 3.5 3 1 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 GAX26930.1 - 1.6 6.3 16.3 4.3 4.8 16.3 1.6 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family DUF2157 PF09925.9 GAX26930.1 - 6.2 6.6 12.5 1 9.1 0.4 3.6 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) RRM_1 PF00076.22 GAX26931.1 - 0.0007 19.4 0.0 0.032 14.1 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MTS PF05175.14 GAX26932.1 - 0.00055 19.5 0.0 0.0009 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX26932.1 - 0.05 14.3 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX26932.1 - 0.16 12.7 0.0 0.51 11.1 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Dickkopf_N PF04706.12 GAX26933.1 - 0.84 10.2 11.7 0.43 11.1 9.1 1.9 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Trm112p PF03966.16 GAX26934.1 - 1.2e-09 38.6 0.1 2.6e-09 37.5 0.1 1.6 1 1 0 1 1 1 1 Trm112p-like protein EIF_2_alpha PF07541.12 GAX26935.1 - 7.5e-39 132.4 0.0 1.6e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 GAX26935.1 - 5.3e-13 49.1 1.7 1.1e-12 48.1 0.5 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Phage_Gp19 PF09355.10 GAX26935.1 - 0.081 13.4 0.1 0.24 11.9 0.1 1.8 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 Ssl1 PF04056.14 GAX26936.1 - 8.4e-54 182.3 0.0 1.2e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 GAX26936.1 - 1.5e-15 57.1 18.0 1.4e-14 54.1 12.4 2.6 2 0 0 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 GAX26936.1 - 8.5e-08 32.8 0.0 2.1e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain IBR PF01485.21 GAX26936.1 - 0.0095 16.1 5.5 0.0095 16.1 5.5 3.3 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain VWA_3 PF13768.6 GAX26936.1 - 0.049 13.6 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain DZR PF12773.7 GAX26936.1 - 2.2 8.4 18.6 0.42 10.7 0.1 2.9 2 1 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 GAX26937.1 - 3.6e-15 56.1 0.0 7.1e-11 42.0 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26937.1 - 4.6e-05 22.8 0.0 9.6e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 GAX26937.1 - 0.008 16.1 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like adh_short_C2 PF13561.6 GAX26938.1 - 2.3e-47 161.5 0.7 3.1e-47 161.1 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX26938.1 - 1.4e-42 145.4 0.2 2.2e-42 144.7 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX26938.1 - 6.7e-14 52.2 1.2 1e-13 51.6 1.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX26938.1 - 4.1e-05 22.9 0.0 6.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAX26938.1 - 0.071 12.5 0.1 0.096 12.1 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Amino_oxidase PF01593.24 GAX26939.1 - 1.3e-16 61.0 0.4 4.3e-14 52.7 0.1 3.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX26939.1 - 1.1e-09 38.3 0.1 2.6e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX26939.1 - 5.3e-06 25.8 1.5 5.6e-05 22.4 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAX26939.1 - 2e-05 24.0 0.2 0.0001 21.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAX26939.1 - 2.4e-05 24.1 2.0 0.00072 19.2 2.0 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX26939.1 - 0.00017 21.0 1.3 0.0012 18.1 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX26939.1 - 0.00038 19.9 0.1 0.0012 18.3 0.1 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAX26939.1 - 0.00087 18.6 0.3 0.0023 17.2 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.12 GAX26939.1 - 0.0024 17.4 20.5 0.0024 17.4 20.5 2.3 2 0 0 2 2 2 1 SDA1 GIDA PF01134.22 GAX26939.1 - 0.0045 16.1 0.4 0.021 13.9 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAX26939.1 - 0.0079 15.3 0.2 0.021 13.9 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 GAX26939.1 - 0.012 14.3 0.1 0.03 13.0 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein GDI PF00996.18 GAX26939.1 - 0.035 12.6 0.1 0.45 9.0 0.1 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox PF00070.27 GAX26939.1 - 0.038 14.5 0.1 0.24 12.0 0.0 2.4 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX26939.1 - 0.19 11.0 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zip PF02535.22 GAX26939.1 - 4.4 6.4 10.5 0.45 9.7 1.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter eIF2A PF08662.11 GAX26940.1 - 3.5e-39 134.7 0.3 2.2e-36 125.6 0.1 3.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 GAX26940.1 - 5.8e-08 32.5 0.2 7.9e-07 28.8 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 GAX26940.1 - 0.0047 17.2 0.0 12 6.3 0.0 4.5 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 GAX26940.1 - 0.0071 15.4 0.0 0.024 13.7 0.0 2.0 1 0 0 1 1 1 1 Coatomer WD associated region Metal_resist PF13801.6 GAX26940.1 - 0.021 15.0 3.8 0.042 14.0 3.8 1.4 1 0 0 1 1 1 0 Heavy-metal resistance DUF1623 PF07785.11 GAX26940.1 - 0.098 12.8 0.0 1.2 9.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1623) Rer1 PF03248.13 GAX26941.1 - 3e-64 215.9 7.9 3.6e-64 215.6 7.9 1.0 1 0 0 1 1 1 1 Rer1 family DUF2207 PF09972.9 GAX26941.1 - 0.22 10.3 3.0 1.2 7.9 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ac110_PIF PF07280.11 GAX26941.1 - 1.9 8.3 7.8 0.69 9.7 1.0 2.7 2 1 0 2 2 2 0 Per os infectivity factor AC110 DUF4131 PF13567.6 GAX26941.1 - 3.3 7.3 7.0 6.1 6.5 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Proteasome PF00227.26 GAX26942.1 - 3.7e-38 130.9 0.1 4.6e-38 130.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit APH PF01636.23 GAX26943.1 - 7e-35 121.1 0.1 1e-34 120.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAX26943.1 - 5.6e-05 22.6 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 GAX26943.1 - 0.029 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_1d PF00750.19 GAX26944.1 - 8.3e-113 376.9 0.0 1.2e-112 376.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAX26944.1 - 7.1e-22 77.8 0.4 1.4e-21 76.8 0.4 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAX26944.1 - 1.3e-10 41.7 0.0 3.6e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GST_C_3 PF14497.6 GAX26944.1 - 0.04 14.1 0.0 0.26 11.5 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.22 GAX26944.1 - 0.16 10.1 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) TMEM215 PF15746.5 GAX26945.1 - 0.013 15.0 2.5 5 6.5 2.8 2.2 2 0 0 2 2 2 0 TMEM215 family SOUL PF04832.12 GAX26946.1 - 1e-35 123.4 0.9 1.8e-35 122.6 0.9 1.4 1 0 0 1 1 1 1 SOUL heme-binding protein Peptidase_M3_N PF08439.10 GAX26946.1 - 0.15 12.3 0.0 0.5 10.7 0.0 1.9 1 0 0 1 1 1 0 Oligopeptidase F LMP PF04778.12 GAX26946.1 - 0.17 11.8 0.6 0.51 10.2 0.1 2.0 3 0 0 3 3 3 0 LMP repeated region PDZ PF00595.24 GAX26947.1 - 6.1e-06 26.5 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX26947.1 - 1e-05 25.2 0.2 3.2e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GAX26947.1 - 0.063 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Aminotran_5 PF00266.19 GAX26948.1 - 4.1e-145 483.4 0.0 4.8e-145 483.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAX26948.1 - 8.7e-07 28.6 0.7 1.6e-05 24.4 0.8 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAX26948.1 - 2.5e-06 26.3 0.2 3.7e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAX26948.1 - 5.1e-06 25.9 0.1 9e-06 25.1 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 GAX26948.1 - 0.00011 20.9 0.0 0.00017 20.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase MORN PF02493.20 GAX26949.1 - 2.8e-43 143.3 42.8 2.4e-07 30.2 0.5 9.5 9 0 0 9 9 9 9 MORN repeat GcpE PF04551.14 GAX26950.1 - 3.7e-150 499.9 0.0 4.3e-150 499.6 0.0 1.0 1 0 0 1 1 1 1 GcpE protein Sgf11 PF08209.11 GAX26950.1 - 0.7 9.5 3.3 1 9.0 0.1 2.5 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) YL1 PF05764.13 GAX26951.1 - 0.00051 20.2 12.5 0.00075 19.7 12.5 1.2 1 1 0 1 1 1 1 YL1 nuclear protein Mem_trans PF03547.18 GAX26951.1 - 0.0075 14.7 0.3 0.0093 14.4 0.3 1.3 1 0 0 1 1 1 1 Membrane transport protein Spt5_N PF11942.8 GAX26951.1 - 0.0081 17.1 7.5 0.0081 17.1 7.5 1.8 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 GAX26951.1 - 0.022 13.1 6.6 0.026 12.8 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 GAX26951.1 - 0.037 13.9 8.6 0.064 13.1 8.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_RNA_Pol_19 PF05320.12 GAX26951.1 - 0.21 11.6 6.7 0.37 10.8 6.7 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit GREB1 PF15782.5 GAX26951.1 - 0.21 8.7 3.6 0.22 8.6 3.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nop14 PF04147.12 GAX26951.1 - 0.56 8.4 20.4 0.28 9.3 18.6 1.3 1 1 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 GAX26951.1 - 0.94 8.8 19.6 0.061 12.7 13.6 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DNA_pol_phi PF04931.13 GAX26951.1 - 1.1 7.3 14.5 1.6 6.8 14.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GAX26951.1 - 1.2 8.3 7.4 1.8 7.7 7.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 GAX26951.1 - 1.2 7.8 4.4 1.6 7.4 4.4 1.4 1 0 0 1 1 1 0 Presenilin CENP-B_dimeris PF09026.10 GAX26951.1 - 1.5 9.2 11.0 11 6.5 9.8 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2052 PF09747.9 GAX26951.1 - 1.8 8.6 14.0 0.23 11.6 10.1 1.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BSP_II PF05432.11 GAX26951.1 - 4.6 6.8 21.9 7 6.3 21.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MAT1 PF06391.13 GAX26951.1 - 9.5 6.0 14.5 0.63 9.8 9.6 1.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Paf67 PF10255.9 GAX26952.1 - 9e-83 278.5 0.0 3.8e-82 276.4 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 ATG22 PF11700.8 GAX26954.1 - 9.3e-21 74.0 24.8 4.1e-19 68.6 24.8 2.1 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAX26954.1 - 2e-10 40.1 33.0 2.1e-10 40.1 31.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CD225 PF04505.12 GAX26954.1 - 0.06 13.5 4.4 0.19 11.9 0.0 3.2 3 0 0 3 3 3 0 Interferon-induced transmembrane protein SPRY PF00622.28 GAX26956.1 - 1.6e-26 92.8 1.0 2.1e-26 92.4 0.1 1.8 2 0 0 2 2 2 1 SPRY domain Telomere_Sde2_2 PF13297.6 GAX26956.1 - 4.1e-24 84.0 0.4 7.4e-24 83.2 0.4 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 GAX26956.1 - 5.7e-14 52.3 8.9 5.7e-14 52.3 8.9 2.2 2 1 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain TLD PF07534.16 GAX26957.1 - 3.6e-26 92.0 0.0 5.2e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 TLD DUF4256 PF14066.6 GAX26957.1 - 0.14 11.8 0.3 0.23 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) Laminin_G_3 PF13385.6 GAX26959.1 - 1.3e-06 28.7 0.1 5e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Cadherin_3 PF16184.5 GAX26959.1 - 0.00034 20.6 0.0 0.031 14.3 0.0 3.3 3 0 0 3 3 3 1 Cadherin-like WW PF00397.26 GAX26959.1 - 0.0016 18.5 0.6 0.0042 17.2 0.6 1.7 1 0 0 1 1 1 1 WW domain Big_9 PF17963.1 GAX26959.1 - 0.0023 18.6 0.0 0.062 14.1 0.0 3.3 3 1 0 3 3 3 1 Bacterial Ig domain Cadherin_4 PF17803.1 GAX26959.1 - 0.0065 17.1 0.0 0.028 15.0 0.0 2.1 1 0 0 1 1 1 1 Bacterial cadherin-like domain DUF2269 PF10027.9 GAX26961.1 - 1.5e-07 31.6 2.1 2.6e-07 30.8 2.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) Pkinase PF00069.25 GAX26962.1 - 2.9e-51 174.3 0.5 5.7e-51 173.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26962.1 - 1.5e-33 116.2 0.0 3e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 GAX26962.1 - 0.0062 16.7 0.1 0.018 15.2 0.1 1.7 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Sds3 PF08598.11 GAX26962.1 - 0.0071 16.4 9.7 0.021 14.8 9.7 1.8 1 0 0 1 1 1 1 Sds3-like RGS12_us1 PF16613.5 GAX26962.1 - 0.17 12.2 5.9 0.72 10.2 5.9 2.2 1 0 0 1 1 1 0 Unstructured region of RGS12 ProSAAS PF07259.12 GAX26962.1 - 0.24 11.3 2.5 0.67 9.9 2.5 1.7 1 0 0 1 1 1 0 ProSAAS precursor Exonuc_VII_L PF02601.15 GAX26962.1 - 3.9 7.0 11.6 0.54 9.8 7.3 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tim17 PF02466.19 GAX26963.1 - 3.4e-05 24.2 0.1 4.6e-05 23.8 0.1 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Voltage_CLC PF00654.20 GAX26964.1 - 3.4e-65 220.6 29.3 3e-64 217.5 24.0 2.0 1 1 0 2 2 2 2 Voltage gated chloride channel HECT PF00632.25 GAX26965.1 - 1.6e-77 261.0 0.0 2.4e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 GAX26965.1 - 7e-31 105.4 32.2 4.4e-08 32.7 0.8 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAX26965.1 - 1.6e-29 102.3 21.5 1.3e-09 38.5 0.2 8.2 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Pentapeptide_4 PF13599.6 GAX26966.1 - 1.5e-24 86.0 2.3 4e-10 39.7 0.1 2.6 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 GAX26966.1 - 4.5e-17 61.3 7.0 1e-09 37.8 1.7 3.7 2 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 GAX26966.1 - 1.5e-09 37.9 9.7 7.6e-09 35.6 0.4 3.3 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) LTD PF00932.19 GAX26966.1 - 0.012 16.0 0.0 1.4 9.3 0.0 2.3 2 1 0 2 2 2 0 Lamin Tail Domain Ank_3 PF13606.6 GAX26967.1 - 0.016 15.7 4.5 2.7 8.8 0.0 4.9 6 0 0 6 6 6 0 Ankyrin repeat Tom37 PF10568.9 GAX26968.1 - 0.00012 22.3 4.2 0.13 12.6 0.0 3.2 3 0 0 3 3 3 2 Outer mitochondrial membrane transport complex protein Peptidase_C69 PF03577.15 GAX26969.1 - 6.7e-60 203.1 6.3 1.6e-56 191.9 6.3 2.9 1 1 0 1 1 1 1 Peptidase family C69 KH_1 PF00013.29 GAX26969.1 - 0.21 11.4 0.3 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 KH domain Bestrophin PF01062.21 GAX26970.1 - 3.9e-17 62.6 2.6 5.6e-17 62.1 2.6 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel cNMP_binding PF00027.29 GAX26970.1 - 2.8e-12 46.5 0.1 4.5e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MnmE_helical PF12631.7 GAX26972.1 - 7.5e-47 160.2 0.4 1e-46 159.7 0.4 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 GAX26972.1 - 1.8e-35 121.7 0.0 4.1e-35 120.6 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 GAX26972.1 - 5e-22 78.1 0.1 9.8e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX26972.1 - 4.6e-10 39.2 0.0 1.5e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX26972.1 - 0.00026 21.1 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 GAX26972.1 - 0.012 16.2 0.0 0.036 14.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF3280 PF11684.8 GAX26972.1 - 0.024 15.0 0.1 0.059 13.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) DUF5569 PF17729.1 GAX26972.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5569) zf-C3HC4_3 PF13920.6 GAX26974.1 - 2e-11 43.6 6.5 3.7e-11 42.7 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH3_3 PF08239.11 GAX26974.1 - 0.00083 19.6 0.0 0.75 10.1 0.0 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain zf-RING_2 PF13639.6 GAX26974.1 - 0.063 13.6 7.9 0.14 12.5 7.9 1.7 1 0 0 1 1 1 0 Ring finger domain zf-P11 PF03854.14 GAX26974.1 - 0.36 10.5 3.6 0.77 9.5 3.6 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_5 PF14634.6 GAX26974.1 - 2.1 8.4 6.5 4.6 7.3 6.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Peptidase_M1 PF01433.20 GAX26976.1 - 1.1e-79 267.0 0.2 1.7e-79 266.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAX26976.1 - 1.9e-66 224.8 0.0 2.8e-65 220.9 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAX26976.1 - 6.4e-42 143.8 0.2 9.7e-42 143.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain WLM PF08325.10 GAX26976.1 - 0.089 12.9 0.0 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 WLM domain SprT-like PF10263.9 GAX26976.1 - 0.097 12.5 0.0 0.83 9.5 0.0 2.3 2 1 0 2 2 2 0 SprT-like family DNA_pol_A_exo1 PF01612.20 GAX26977.1 - 1.1e-13 51.3 0.0 4.7e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease Ank_2 PF12796.7 GAX26977.1 - 3.2e-09 37.3 0.1 6.9e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX26977.1 - 3.7e-07 30.3 0.1 0.0021 18.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX26977.1 - 4.1e-07 30.2 0.1 0.062 13.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GAX26977.1 - 4.4e-05 23.6 0.1 0.33 11.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAX26977.1 - 0.001 19.6 0.1 0.1 13.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NAP PF00956.18 GAX26977.1 - 0.0094 15.2 0.2 0.014 14.6 0.2 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) TEX15 PF15326.6 GAX26977.1 - 0.091 12.5 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Testis expressed sequence 15 Polyketide_cyc2 PF10604.9 GAX26978.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAX26978.1 - 0.022 14.9 0.0 0.05 13.8 0.0 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Pkinase PF00069.25 GAX26979.1 - 5.2e-21 75.2 0.0 6.9e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX26979.1 - 3.7e-12 46.1 0.0 5.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX26979.1 - 0.023 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX26979.1 - 0.04 13.2 0.0 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like PIP49_C PF12260.8 GAX26979.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 MMR_HSR1_Xtn PF16897.5 GAX26980.1 - 1.1e-34 118.7 0.0 2e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 GAX26980.1 - 6e-20 71.4 0.0 1.4e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 GAX26980.1 - 1.6e-17 63.3 0.0 2.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 GAX26980.1 - 1.8e-09 37.3 0.0 3.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX26980.1 - 3.4e-05 24.0 0.1 0.029 14.4 0.0 2.5 1 1 0 2 2 2 2 Dynamin family AIG1 PF04548.16 GAX26980.1 - 0.0007 19.0 0.3 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 AIG1 family SRPRB PF09439.10 GAX26980.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 GAX26980.1 - 0.13 12.5 0.7 0.52 10.5 0.0 2.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 GAX26980.1 - 1.1 9.4 3.1 0.55 10.5 0.2 1.9 2 0 0 2 2 2 0 AAA domain Y1_Tnp PF01797.16 GAX26981.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.9 1 1 0 1 1 1 0 Transposase IS200 like ATP-grasp_4 PF13535.6 GAX26982.1 - 1.8e-14 53.6 0.1 3.3e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAX26982.1 - 6.3e-11 42.6 0.0 9.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAX26982.1 - 2.6e-07 30.6 0.0 6.3e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 GAX26982.1 - 1.7e-06 27.8 0.0 6.3e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon FERM_N_2 PF18038.1 GAX26982.1 - 0.04 14.7 1.3 0.14 13.0 0.5 2.1 1 1 0 2 2 2 0 FERM N-terminal domain Dala_Dala_lig_C PF07478.13 GAX26982.1 - 0.046 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus GSH-S_ATP PF02955.16 GAX26982.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_5 PF13549.6 GAX26982.1 - 0.076 12.4 0.0 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain T3SS_ATPase_C PF18269.1 GAX26983.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain PALP PF00291.25 GAX26984.1 - 3.9e-27 95.4 0.0 1.1e-12 48.0 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 GAX26985.1 - 6.3e-12 46.0 0.0 9.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain zf-MYND PF01753.18 GAX26985.1 - 0.032 14.3 0.4 0.064 13.4 0.1 1.6 2 0 0 2 2 2 0 MYND finger MMR_HSR1 PF01926.23 GAX26986.1 - 2.7e-11 43.6 0.0 2.2e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX26986.1 - 6.2e-05 22.6 0.0 0.0026 17.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX26986.1 - 0.0021 18.0 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase IBB PF01749.20 GAX26986.1 - 0.0059 17.0 1.8 0.0059 17.0 1.8 2.8 3 0 0 3 3 3 1 Importin beta binding domain CNDH2_C PF16858.5 GAX26986.1 - 0.62 9.9 6.6 5.5 6.8 1.1 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop53 PF07767.11 GAX26986.1 - 1.5 8.1 18.4 3.9 6.8 5.6 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) AAA_22 PF13401.6 GAX26987.1 - 3.7e-05 24.0 0.0 0.00011 22.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAX26987.1 - 0.00014 22.4 0.3 0.72 10.4 0.3 2.4 1 1 1 2 2 2 2 ABC transporter AAA_33 PF13671.6 GAX26987.1 - 0.00016 21.9 0.0 0.00033 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 GAX26987.1 - 0.0014 18.1 0.2 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 GAX26987.1 - 0.012 14.8 0.1 0.033 13.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TMEM154 PF15102.6 GAX26987.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family AAA_21 PF13304.6 GAX26987.1 - 0.02 14.7 1.3 2.5 7.8 0.9 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX26987.1 - 0.03 14.7 0.1 0.1 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 GAX26987.1 - 0.036 13.7 0.1 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G0-G1_switch_2 PF15103.6 GAX26987.1 - 0.041 14.3 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 RsgA_GTPase PF03193.16 GAX26987.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Phage_holin_T PF11031.8 GAX26987.1 - 0.054 13.0 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage T holin NACHT PF05729.12 GAX26987.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sensor PF13796.6 GAX26987.1 - 0.078 13.0 0.4 0.078 13.0 0.4 2.6 2 1 0 2 2 2 0 Putative sensor AAA_29 PF13555.6 GAX26987.1 - 0.14 11.9 0.3 0.4 10.4 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Wzy_C PF04932.15 GAX26987.1 - 0.15 11.7 6.7 0.51 10.0 0.0 2.6 2 1 0 2 2 2 0 O-Antigen ligase DUF4574 PF15141.6 GAX26987.1 - 0.21 11.5 0.9 22 5.0 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 LapA_dom PF06305.11 GAX26987.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.6 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 GAX26987.1 - 0.32 11.9 0.0 0.32 11.9 0.0 2.2 3 0 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain ABC2_membrane_2 PF12679.7 GAX26987.1 - 5 6.3 12.0 34 3.6 0.0 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein 4HBT PF03061.22 GAX26988.1 - 0.031 14.6 0.0 0.098 13.0 0.0 2.0 2 0 0 2 2 2 0 Thioesterase superfamily DUF1350 PF07082.11 GAX26989.1 - 1.8e-28 99.5 0.0 7.2e-17 61.5 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1350) Sel1 PF08238.12 GAX26989.1 - 3.8e-15 56.0 0.0 2e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 Sel1 repeat DUF4820 PF16091.5 GAX26989.1 - 0.22 10.9 5.2 0.16 11.3 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4834 PF16118.5 GAX26989.1 - 0.35 11.9 2.6 5.2 8.1 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RXT2_N PF08595.11 GAX26989.1 - 1.2 9.2 15.2 1.8 8.6 4.1 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4746 PF15928.5 GAX26989.1 - 3.4 7.0 5.9 2.2 7.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Importin_rep_6 PF18829.1 GAX26989.1 - 4.1 7.6 13.9 0.63 10.2 0.3 2.8 3 0 0 3 3 3 0 Importin repeat 6 Nucleo_P87 PF07267.11 GAX26989.1 - 7.7 5.2 13.9 1.6 7.5 1.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 LAT PF15234.6 GAX26989.1 - 7.8 6.1 12.4 0.8 9.4 0.2 2.3 2 0 0 2 2 2 0 Linker for activation of T-cells Gly_transf_sug PF04488.15 GAX26991.1 - 1.3e-06 29.0 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAX26991.1 - 0.0043 16.5 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 GAX26991.1 - 0.0051 16.2 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DUF3328 PF11807.8 GAX26991.1 - 0.053 13.3 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Tlr3_TMD PF17968.1 GAX26991.1 - 2.5 8.3 4.4 5.3 7.3 4.4 1.4 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain bZIP_2 PF07716.15 GAX26992.1 - 1.7e-10 40.8 25.6 7.6e-06 25.9 3.0 2.5 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 GAX26992.1 - 9.7e-10 38.4 24.9 3.8e-06 26.9 13.9 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 GAX26992.1 - 0.00012 22.5 16.8 0.0036 17.8 1.0 2.4 2 0 0 2 2 2 2 bZIP Maf transcription factor DUF4140 PF13600.6 GAX26992.1 - 0.0013 19.1 4.0 1.5 9.3 0.0 3.1 2 1 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) ABC_tran_CTD PF16326.5 GAX26992.1 - 0.014 15.6 5.8 0.59 10.4 2.2 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain CCDC106 PF15794.5 GAX26992.1 - 0.076 12.7 14.8 0.15 11.7 5.3 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 106 CENP-F_leu_zip PF10473.9 GAX26992.1 - 0.25 11.4 13.3 0.74 9.8 4.6 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 GAX26992.1 - 0.45 10.5 7.3 0.33 10.9 0.9 2.8 2 1 0 2 2 2 0 Prefoldin subunit DUF4164 PF13747.6 GAX26992.1 - 0.73 10.2 13.8 0.43 10.9 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CENP-Q PF13094.6 GAX26992.1 - 0.97 9.6 14.6 2 8.6 1.9 2.6 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Seryl_tRNA_N PF02403.22 GAX26992.1 - 1.4 9.2 11.3 6.1 7.1 4.1 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4094 PF13334.6 GAX26992.1 - 2.4 8.6 5.2 4.4 7.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) UPF0242 PF06785.11 GAX26992.1 - 2.6 8.1 10.3 3 7.9 2.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 GAX26992.1 - 3.8 7.6 12.5 6.3 7.0 1.5 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase EMP24_GP25L PF01105.24 GAX26992.1 - 4.1 7.3 7.1 2.8 7.8 0.2 2.9 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4337 PF14235.6 GAX26992.1 - 4.1 7.5 9.3 0.27 11.3 3.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) ASD2 PF08687.11 GAX26992.1 - 4.3 6.8 15.9 0.67 9.5 7.0 2.2 1 1 0 2 2 2 0 Apx/Shroom domain ASD2 VSG_B PF13206.6 GAX26992.1 - 4.5 6.4 8.8 1 8.5 4.6 1.8 1 1 0 2 2 2 0 Trypanosomal VSG domain TMF_TATA_bd PF12325.8 GAX26992.1 - 4.7 7.5 16.1 2.9 8.1 4.8 3.2 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF5320 PF17253.2 GAX26992.1 - 7.3 7.7 5.8 15 6.7 1.3 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Uds1 PF15456.6 GAX26992.1 - 7.4 6.8 13.8 2.4 8.3 4.3 2.8 2 1 0 2 2 2 0 Up-regulated During Septation GrpE PF01025.19 GAX26993.1 - 4.4e-18 65.5 4.9 1.4e-17 63.9 4.9 1.7 1 1 0 1 1 1 1 GrpE DUF4763 PF15960.5 GAX26993.1 - 0.081 12.2 5.1 0.11 11.8 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 GAX26993.1 - 0.09 11.6 7.2 0.12 11.2 7.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1459 PF07312.11 GAX26993.1 - 0.15 12.3 0.4 0.32 11.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) DUF4407 PF14362.6 GAX26993.1 - 0.6 9.4 4.8 0.82 9.0 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 GAX26993.1 - 0.87 9.4 5.3 0.87 9.4 3.7 1.7 1 1 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.9 GAX26993.1 - 2.5 8.0 8.9 3.8 7.4 8.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain CENP-H PF05837.12 GAX26993.1 - 7.1 7.1 7.8 2.8 8.4 4.2 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PRP38 PF03371.15 GAX26994.1 - 8e-41 139.8 0.0 1.1e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 PRP38 family DUF411 PF04214.13 GAX26994.1 - 0.22 11.5 0.0 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF Presenilin PF01080.17 GAX26994.1 - 1.2 7.8 8.8 1.6 7.4 8.8 1.1 1 0 0 1 1 1 0 Presenilin 7TM_GPCR_Sri PF10327.9 GAX26995.1 - 0.08 12.1 2.2 0.05 12.8 0.3 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sri RRM_1 PF00076.22 GAX26996.1 - 2e-36 123.6 0.0 1.9e-18 66.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX26996.1 - 5.6e-07 29.6 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GAX26996.1 - 0.0076 16.2 0.0 0.056 13.4 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAX26996.1 - 0.075 12.9 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif GidB PF02527.15 GAX26996.1 - 0.3 10.4 1.4 0.51 9.6 1.4 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NTP_transf_6 PF06042.11 GAX26997.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase Aldose_epim PF01263.20 GAX27002.1 - 0.00017 21.0 0.1 0.00055 19.3 0.0 1.9 3 0 0 3 3 3 1 Aldose 1-epimerase NtCtMGAM_N PF16863.5 GAX27002.1 - 0.019 15.1 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase PaO PF08417.12 GAX27003.1 - 0.034 14.3 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 Pheophorbide a oxygenase Caenor_Her-1 PF09232.10 GAX27003.1 - 0.057 13.6 0.4 0.11 12.6 0.2 1.5 1 1 0 1 1 1 0 Caenorhabditis elegans Her-1 ClpS PF02617.17 GAX27004.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS MORN PF02493.20 GAX27005.1 - 0.00014 21.6 2.6 0.00014 21.6 2.6 3.1 3 0 0 3 3 3 1 MORN repeat Dpy-30 PF05186.13 GAX27006.1 - 3.6e-18 65.0 0.5 4.9e-18 64.5 0.5 1.2 1 0 0 1 1 1 1 Dpy-30 motif IreB PF06135.12 GAX27006.1 - 0.056 13.7 0.1 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 IreB regulatory phosphoprotein TFIIA PF03153.13 GAX27006.1 - 1.4 8.8 10.4 1.3 8.9 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 GAX27006.1 - 9.2 5.1 26.3 11 4.9 26.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Myosin_head PF00063.21 GAX27007.1 - 5.6e-186 619.7 3.2 5.6e-186 619.7 3.2 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_16 PF13191.6 GAX27007.1 - 0.0043 17.4 0.0 0.0043 17.4 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain IQ PF00612.27 GAX27007.1 - 0.026 14.3 0.5 0.084 12.7 0.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.6 GAX27007.1 - 0.036 14.3 0.0 0.32 11.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Maelstrom PF13017.6 GAX27007.1 - 0.045 13.4 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Piwi PF02171.17 GAX27008.1 - 1.7e-30 106.3 0.0 3.2e-30 105.4 0.0 1.5 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.22 GAX27008.1 - 0.0026 17.5 0.2 0.0078 16.0 0.2 1.7 1 0 0 1 1 1 1 PAZ domain Myosin_head PF00063.21 GAX27010.1 - 6.7e-181 602.9 1.6 6.7e-181 602.9 1.6 2.0 2 1 1 3 3 3 1 Myosin head (motor domain) AAA_22 PF13401.6 GAX27010.1 - 0.098 12.9 0.0 0.88 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAX27010.1 - 0.11 12.9 2.3 0.58 10.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAX27010.1 - 0.12 12.7 1.5 0.74 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain CRF PF00473.17 GAX27010.1 - 0.33 11.1 1.6 1.5 9.0 1.6 2.2 1 0 0 1 1 1 0 Corticotropin-releasing factor family Myosin_head PF00063.21 GAX27011.1 - 1.3e-175 585.5 0.0 1.3e-175 585.5 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 GAX27011.1 - 0.00011 21.9 0.2 0.00054 19.7 0.2 2.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 GAX27011.1 - 0.035 13.9 0.8 0.087 12.7 0.8 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.6 GAX27011.1 - 0.043 14.1 0.3 1 9.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAX27011.1 - 0.059 13.8 0.0 0.059 13.8 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain SPOR PF05036.13 GAX27011.1 - 0.13 12.7 1.0 1.5 9.3 0.0 2.9 2 0 0 2 2 2 0 Sporulation related domain peroxidase PF00141.23 GAX27012.1 - 4.2e-46 157.5 0.0 6.6e-46 156.9 0.0 1.3 1 1 0 1 1 1 1 Peroxidase Glyco_hydro_47 PF01532.20 GAX27013.1 - 2.2e-137 458.7 0.0 2.6e-137 458.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HATPase_c_3 PF13589.6 GAX27014.1 - 1.5e-06 28.1 0.0 4.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DivIC PF04977.15 GAX27014.1 - 0.033 14.0 2.1 0.074 12.8 2.1 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4715 PF15835.5 GAX27014.1 - 0.059 13.4 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Lzipper-MIP1 PF14389.6 GAX27014.1 - 0.15 12.4 7.0 1.8 8.9 0.6 2.9 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TPD52 PF04201.15 GAX27014.1 - 3.5 7.2 5.3 1.7 8.2 1.7 2.0 2 0 0 2 2 2 0 Tumour protein D52 family GPAT_N PF14829.6 GAX27015.1 - 0.15 12.0 0.0 20 5.3 0.0 2.8 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal ABC_tran PF00005.27 GAX27016.1 - 2.7e-43 147.8 2.8 4.7e-20 72.5 0.0 4.0 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX27016.1 - 3e-21 75.2 8.2 3e-21 75.2 8.2 4.1 4 1 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 GAX27016.1 - 3.1e-17 63.4 2.0 0.00011 22.1 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX27016.1 - 6.9e-09 35.5 1.2 0.035 13.5 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX27016.1 - 2.7e-07 30.2 0.0 0.034 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAX27016.1 - 5.7e-07 30.0 0.3 0.0092 16.4 0.0 3.4 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 GAX27016.1 - 6.1e-06 26.2 0.0 0.029 14.3 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAX27016.1 - 1.9e-05 24.9 0.0 0.073 13.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX27016.1 - 2.3e-05 25.0 4.2 0.049 14.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 GAX27016.1 - 3e-05 24.5 2.0 0.12 12.8 0.0 3.0 3 1 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAX27016.1 - 0.00014 21.9 0.1 0.85 9.7 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAX27016.1 - 0.00014 22.2 3.0 0.32 11.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 GAX27016.1 - 0.00033 20.5 0.4 0.39 10.4 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GAX27016.1 - 0.00053 19.8 20.7 0.054 13.2 0.0 5.3 5 1 0 6 6 6 2 AAA ATPase domain AAA_33 PF13671.6 GAX27016.1 - 0.0006 20.0 0.0 0.41 10.8 0.1 2.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 GAX27016.1 - 0.001 18.8 0.2 0.75 9.5 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 GAX27016.1 - 0.0011 18.9 1.1 1.3 9.0 0.2 2.6 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 GAX27016.1 - 0.0011 19.0 0.2 2.6 8.1 0.0 3.9 4 1 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 GAX27016.1 - 0.0015 18.9 0.7 0.94 9.9 0.0 3.0 3 1 0 3 3 2 1 RNA helicase AAA_5 PF07728.14 GAX27016.1 - 0.0015 18.5 0.1 1.4 8.9 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 GAX27016.1 - 0.003 17.5 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GAX27016.1 - 0.0034 17.2 0.0 0.92 9.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 GAX27016.1 - 0.0037 17.8 28.2 0.042 14.3 2.0 4.9 4 1 0 4 4 3 2 AAA domain AAA_25 PF13481.6 GAX27016.1 - 0.0043 16.6 2.5 1.1 8.8 0.0 3.0 4 0 0 4 4 2 1 AAA domain Seryl_tRNA_N PF02403.22 GAX27016.1 - 0.0067 16.6 1.6 0.0067 16.6 1.6 3.3 3 0 0 3 3 2 1 Seryl-tRNA synthetase N-terminal domain NB-ARC PF00931.22 GAX27016.1 - 0.0073 15.5 0.0 3.7 6.6 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 GAX27016.1 - 0.023 14.2 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2205 PF10224.9 GAX27016.1 - 0.024 14.6 0.2 0.18 11.8 0.2 2.6 1 0 0 1 1 1 0 Short coiled-coil protein AAA_30 PF13604.6 GAX27016.1 - 0.042 13.6 3.7 2.9 7.6 0.4 3.2 3 1 0 3 3 2 0 AAA domain KTI12 PF08433.10 GAX27016.1 - 0.043 13.3 1.2 0.14 11.6 1.2 1.8 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 GAX27016.1 - 0.046 13.6 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 GAX27016.1 - 0.095 11.7 0.8 3.1 6.7 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 GAX27016.1 - 0.53 10.2 8.7 2.1 8.2 0.0 3.6 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 GAX27016.1 - 0.58 9.7 5.3 10 5.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 GAX27016.1 - 0.62 9.8 3.4 6.7 6.5 0.0 3.3 3 1 1 4 4 4 0 MukB N-terminal DUF87 PF01935.17 GAX27016.1 - 1.9 8.6 0.0 1.9 8.6 0.0 4.0 5 0 0 5 5 5 0 Helicase HerA, central domain Dynamin_N PF00350.23 GAX27016.1 - 5.2 7.1 8.3 46 4.0 0.0 4.4 3 1 0 4 4 4 0 Dynamin family DUF543 PF04418.12 GAX27017.1 - 6.9e-08 32.4 0.1 7.5e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Rick_17kDa_Anti PF05433.15 GAX27017.1 - 0.073 12.9 19.1 0.14 12.1 19.1 1.4 1 1 0 1 1 1 0 Glycine zipper 2TM domain MFS_1 PF07690.16 GAX27018.1 - 1e-17 64.2 36.6 1e-17 64.2 36.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3302 PF11742.8 GAX27018.1 - 0.28 11.4 1.7 8.7 6.5 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) SPC12 PF06645.13 GAX27018.1 - 3.8 7.7 5.9 11 6.2 0.9 3.5 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TerY_C PF15616.6 GAX27019.1 - 0.14 12.3 1.7 0.23 11.6 1.7 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain Rhomboid PF01694.22 GAX27020.1 - 1.3e-30 106.4 6.9 1.3e-30 106.4 6.9 1.9 3 0 0 3 3 3 1 Rhomboid family Myc_N PF01056.18 GAX27020.1 - 0.21 11.5 0.8 0.31 10.9 0.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 GAX27020.1 - 8.2 5.7 7.5 13 5.0 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein PMI_typeI PF01238.21 GAX27021.1 - 4e-93 312.6 0.0 3.3e-92 309.5 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I DegT_DnrJ_EryC1 PF01041.17 GAX27021.1 - 0.078 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cupin_2 PF07883.11 GAX27021.1 - 0.16 11.7 0.3 15 5.4 0.0 2.9 3 0 0 3 3 3 0 Cupin domain Radical_SAM_C PF16199.5 GAX27022.1 - 3.3e-31 107.2 0.1 6.2e-31 106.3 0.1 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 GAX27022.1 - 1.7e-18 67.5 0.0 7.2e-18 65.5 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 GAX27022.1 - 9e-09 35.6 0.1 2.8e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX27022.1 - 5.2e-05 23.2 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX27022.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Alpha-mann_mid PF09261.11 GAX27022.1 - 0.17 12.1 0.0 4.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Alpha mannosidase middle domain HMG_box PF00505.19 GAX27023.1 - 9.3e-10 38.8 2.3 2.6e-06 27.8 0.2 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27023.1 - 1.5e-08 35.1 4.8 1.3e-07 32.1 4.8 2.2 1 1 0 1 1 1 1 HMG-box domain MRI PF15325.6 GAX27023.1 - 0.27 12.3 0.2 0.27 12.3 0.2 2.5 3 0 0 3 3 3 0 Modulator of retrovirus infection Pkinase PF00069.25 GAX27024.1 - 1.3e-48 165.7 0.0 9.1e-34 117.0 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAX27024.1 - 1.8e-23 83.2 0.0 4.2e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase B56 PF01603.20 GAX27024.1 - 9.9e-20 70.9 9.4 1.5e-19 70.3 9.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) IDH PF03971.14 GAX27025.1 - 0 1166.1 0.8 0 1165.9 0.8 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase DnaJ PF00226.31 GAX27026.1 - 2.9e-09 36.9 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Sulfotransfer_1 PF00685.27 GAX27027.1 - 0.00019 21.0 0.0 0.0004 19.9 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain PilS PF08805.11 GAX27028.1 - 0.014 15.2 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 PilS N terminal Myb_DNA-binding PF00249.31 GAX27029.1 - 1.2e-11 44.6 0.1 4.2e-11 42.9 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX27029.1 - 2.8e-05 24.3 0.2 0.00017 21.8 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain LysM PF01476.20 GAX27031.1 - 0.00014 21.8 0.0 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 LysM domain PA PF02225.22 GAX27032.1 - 4.9e-06 26.5 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF3619 PF12279.8 GAX27032.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF1610 PF07754.11 GAX27033.1 - 0.18 11.8 3.5 0.31 11.0 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Prok-RING_1 PF14446.6 GAX27033.1 - 2.6 8.0 8.7 2.6 8.0 5.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF1995 PF09353.10 GAX27035.1 - 2.6e-29 102.7 0.0 4.3e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF2470 PF10615.9 GAX27035.1 - 0.00048 20.7 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) HMG_box PF00505.19 GAX27037.1 - 4.9e-10 39.7 4.3 1.6e-07 31.6 1.2 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27037.1 - 1.7e-06 28.5 6.2 5.1e-05 23.8 1.1 2.8 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.6 GAX27037.1 - 0.027 14.5 1.4 0.054 13.5 0.1 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 LsmAD PF06741.13 GAX27038.1 - 2e-23 82.7 1.8 2e-23 82.7 1.8 2.2 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 GAX27038.1 - 1.6e-13 50.6 0.0 4.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 GAX27038.1 - 9.4e-06 25.0 2.7 0.015 14.9 0.2 2.8 1 1 1 2 2 2 2 Ataxin-2 C-terminal region Gemin7 PF11095.8 GAX27038.1 - 0.0061 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) TPR_2 PF07719.17 GAX27039.1 - 2.3e-10 39.8 9.4 0.00017 21.4 0.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX27039.1 - 2e-09 36.8 10.4 4.6e-05 23.1 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX27039.1 - 7.2e-05 22.4 1.4 0.24 11.1 0.3 2.9 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 GAX27039.1 - 0.00015 21.7 4.6 0.14 12.5 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX27039.1 - 0.0056 16.9 6.4 3.9 7.8 2.8 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX27039.1 - 0.051 14.2 0.4 14 6.4 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 GAX27039.1 - 0.39 10.8 7.6 0.36 10.9 0.3 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 GAX27039.1 - 0.65 10.1 4.0 15 5.6 0.2 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) HA PF03457.14 GAX27040.1 - 7.4e-25 87.1 1.4 2.6e-09 37.3 0.0 5.9 6 0 0 6 6 6 3 Helicase associated domain DUF2459 PF09601.10 GAX27040.1 - 0.051 13.4 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Transglut_core2 PF13369.6 GAX27041.1 - 8.4e-35 119.6 0.0 1.7e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Mating_N PF12731.7 GAX27041.1 - 0.096 12.8 0.3 1.6 8.9 0.1 2.7 3 0 0 3 3 3 0 Mating-type protein beta 1 UPF0565 PF10561.9 GAX27041.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Transglut_core2 PF13369.6 GAX27042.1 - 5.1e-16 58.6 0.4 9.8e-16 57.7 0.2 1.5 1 1 1 2 2 2 1 Transglutaminase-like superfamily Lyase_1 PF00206.20 GAX27043.1 - 1.9e-98 329.8 0.0 2.4e-98 329.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GAX27043.1 - 1.2e-16 60.8 0.5 5.4e-16 58.7 0.0 2.5 3 0 0 3 3 3 1 Fumarase C C-terminus Methyltransf_25 PF13649.6 GAX27044.1 - 1.4e-13 51.3 0.0 8.6e-12 45.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX27044.1 - 1.3e-11 44.9 0.0 1.8e-10 41.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX27044.1 - 3.1e-10 40.1 0.0 6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX27044.1 - 3.2e-09 36.5 0.0 0.0005 19.5 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAX27044.1 - 1.3e-06 28.3 0.0 2.8e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX27044.1 - 8.5e-06 26.4 0.0 0.0013 19.4 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 GAX27044.1 - 0.00034 20.0 0.0 0.0097 15.2 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 GAX27044.1 - 0.00065 19.3 0.1 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAX27044.1 - 0.0034 17.4 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAX27044.1 - 0.15 11.5 0.2 0.48 9.9 0.0 1.9 3 0 0 3 3 3 0 Putative methyltransferase Trypsin_2 PF13365.6 GAX27045.1 - 1.1e-06 29.6 0.1 2.3e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX27045.1 - 1.5e-05 25.0 2.1 7.2e-05 22.7 2.1 1.9 1 1 0 1 1 1 1 Trypsin Kazal_2 PF07648.15 GAX27045.1 - 0.0039 17.3 3.7 0.011 15.8 3.7 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 GAX27045.1 - 0.0053 16.7 5.5 0.0087 16.1 3.9 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain DUF956 PF06115.11 GAX27045.1 - 0.082 12.6 0.2 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Peptidase_S46 PF10459.9 GAX27045.1 - 0.13 10.9 0.2 2.1 6.9 0.1 2.0 2 0 0 2 2 2 0 Peptidase S46 EAGR_box PF16713.5 GAX27045.1 - 0.37 10.5 1.6 0.84 9.4 1.6 1.6 1 0 0 1 1 1 0 Enriched in aromatic and glycine Residues box Trypsin PF00089.26 GAX27046.1 - 1.2e-07 31.7 0.1 3.2e-07 30.4 0.1 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX27046.1 - 5.1e-07 30.7 0.1 1.6e-06 29.1 0.0 1.9 2 1 0 2 2 2 1 Trypsin-like peptidase domain Kazal_1 PF00050.21 GAX27046.1 - 5.9e-05 23.0 3.5 0.00017 21.5 3.5 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GAX27046.1 - 0.0001 22.3 4.4 0.0001 22.3 4.4 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Peptidase_S32 PF05579.13 GAX27046.1 - 0.0041 16.3 0.8 0.0088 15.3 0.1 1.7 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 GAX27046.1 - 0.017 13.8 3.3 0.061 12.0 0.2 2.0 2 0 0 2 2 2 0 Peptidase S46 Trypsin PF00089.26 GAX27047.1 - 1.1e-06 28.7 0.2 2.9e-06 27.3 0.2 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX27047.1 - 3.5e-06 28.0 0.0 7.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kazal_2 PF07648.15 GAX27047.1 - 0.0014 18.7 3.0 0.0027 17.8 3.0 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 GAX27047.1 - 0.0018 18.3 0.5 0.0037 17.2 0.5 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Trypsin PF00089.26 GAX27048.1 - 0.0068 16.2 1.1 0.045 13.6 1.1 2.1 1 1 0 1 1 1 1 Trypsin Kazal_1 PF00050.21 GAX27048.1 - 0.012 15.6 2.9 0.037 14.1 2.9 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Trypsin_2 PF13365.6 GAX27048.1 - 0.015 16.2 0.3 0.031 15.2 0.3 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Kazal_2 PF07648.15 GAX27048.1 - 0.15 12.2 5.7 0.39 10.9 5.7 1.7 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Trypsin_2 PF13365.6 GAX27049.1 - 0.00012 23.0 0.0 0.00029 21.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Kazal_1 PF00050.21 GAX27049.1 - 0.00015 21.7 0.4 0.0004 20.3 0.4 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GAX27049.1 - 0.0023 18.0 3.4 0.0049 17.0 3.4 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Trypsin PF00089.26 GAX27049.1 - 0.024 14.5 0.1 0.071 12.9 0.1 1.7 1 1 0 1 1 1 0 Trypsin Peptidase_S32 PF05579.13 GAX27049.1 - 0.13 11.5 0.2 0.46 9.6 0.0 1.8 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.26 GAX27050.1 - 1.1e-06 28.6 0.1 2e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX27050.1 - 3.9e-05 24.6 0.0 8.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF31 PF01732.16 GAX27050.1 - 0.00095 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 GAX27050.1 - 0.0075 16.1 0.1 0.021 14.7 0.1 1.7 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Kazal_1 PF00050.21 GAX27050.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.2 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Peptidase_C4 PF00863.19 GAX27050.1 - 0.064 12.6 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C4 Kazal_2 PF07648.15 GAX27050.1 - 2.1 8.5 9.9 0.074 13.2 3.4 2.0 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Trypsin_2 PF13365.6 GAX27051.1 - 2.4e-05 25.3 0.0 5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kazal_1 PF00050.21 GAX27051.1 - 0.00018 21.4 1.0 0.00048 20.1 1.0 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GAX27051.1 - 0.00021 21.4 2.3 0.00021 21.4 2.3 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Trypsin PF00089.26 GAX27051.1 - 0.0064 16.3 0.5 0.049 13.4 0.0 2.1 2 0 0 2 2 2 1 Trypsin Beta_propel PF09826.9 GAX27052.1 - 1.8e-90 304.2 0.0 3.4e-90 303.3 0.0 1.4 1 1 0 1 1 1 1 Beta propeller domain EST1_DNA_bind PF10373.9 GAX27053.1 - 1.8e-27 96.6 0.3 2.7e-27 96.0 0.3 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 GAX27053.1 - 3e-08 34.4 0.1 1.4e-07 32.3 0.0 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_1 PF00515.28 GAX27053.1 - 0.005 16.6 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX27053.1 - 0.01 16.0 0.0 0.044 14.0 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX27053.1 - 0.087 13.1 0.0 0.34 11.2 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX27053.1 - 0.094 12.9 0.1 0.36 11.1 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX27053.1 - 0.1 12.7 0.5 0.73 10.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX27053.1 - 0.14 13.0 0.0 0.78 10.7 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Fucokinase PF07959.12 GAX27054.1 - 2.6e-76 257.2 0.0 3.9e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 GAX27054.1 - 3e-09 37.1 0.1 1.1e-08 35.3 0.1 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAX27054.1 - 0.00067 19.8 0.2 0.004 17.4 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain Hexapep PF00132.24 GAX27054.1 - 3 7.7 5.5 18 5.2 0.5 3.5 3 0 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) DnaJ PF00226.31 GAX27055.1 - 3.8e-17 62.2 1.4 8e-17 61.1 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain Zn_clus PF00172.18 GAX27055.1 - 0.00057 20.0 12.3 1.6 8.9 0.2 3.5 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain EcoR124_C PF12008.8 GAX27055.1 - 0.0008 19.1 0.5 0.0015 18.3 0.5 1.4 1 0 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal UPF0506 PF11703.8 GAX27055.1 - 3.1 8.2 14.4 5.7 7.4 0.6 3.4 3 0 0 3 3 3 0 UPF0506 Myosin_head PF00063.21 GAX27056.1 - 2.4e-185 617.7 0.0 2.4e-185 617.7 0.0 2.6 2 1 0 3 3 3 1 Myosin head (motor domain) IQ PF00612.27 GAX27056.1 - 3.4e-11 41.9 4.3 0.0042 16.8 0.2 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif TMEM192 PF14802.6 GAX27056.1 - 0.11 11.5 2.5 16 4.5 4.3 2.3 2 0 0 2 2 2 0 TMEM192 family DUF4116 PF13475.6 GAX27056.1 - 0.16 11.8 0.8 6.8 6.5 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) AAA_16 PF13191.6 GAX27056.1 - 0.61 10.4 0.0 0.61 10.4 0.0 3.5 3 1 0 4 4 4 0 AAA ATPase domain V_ATPase_I PF01496.19 GAX27056.1 - 3.6 5.4 17.2 6.1 4.6 17.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IGPS PF00218.21 GAX27057.1 - 7.3e-18 64.7 1.2 3.1e-17 62.6 1.2 1.8 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase OMPdecase PF00215.24 GAX27057.1 - 0.021 14.4 1.0 0.091 12.3 0.7 2.0 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Bromodomain PF00439.25 GAX27058.1 - 1.1e-31 108.8 0.0 1.8e-15 56.7 0.0 2.6 2 0 0 2 2 2 2 Bromodomain HAT_KAT11 PF08214.11 GAX27058.1 - 3.3e-23 82.6 0.0 5.5e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein PHD_4 PF16866.5 GAX27058.1 - 0.013 15.5 0.9 0.013 15.5 0.9 4.1 5 0 0 5 5 5 0 PHD-finger TPR_1 PF00515.28 GAX27059.1 - 1e-05 25.1 0.0 0.014 15.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Arm PF00514.23 GAX27059.1 - 0.0014 18.6 4.2 1.7 8.8 0.1 4.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Fis1_TPR_C PF14853.6 GAX27059.1 - 0.0042 17.1 0.3 0.014 15.4 0.3 1.9 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 GAX27059.1 - 0.0077 16.3 4.4 4.6 7.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX27059.1 - 0.15 12.4 2.0 2.8 8.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Fasciclin PF02469.22 GAX27060.1 - 3e-27 95.4 0.0 4e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 GAX27061.1 - 1e-50 171.3 0.0 3.2e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Imm51 PF15595.6 GAX27061.1 - 0.035 14.0 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 51 DUF5525 PF17663.1 GAX27061.1 - 0.046 11.8 3.9 0.064 11.3 3.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DEC-1_N PF04625.13 GAX27061.1 - 0.086 11.8 4.4 0.14 11.1 4.4 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SOBP PF15279.6 GAX27061.1 - 0.29 11.7 5.7 0.41 11.2 5.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MS_channel PF00924.18 GAX27062.1 - 2.8e-16 59.7 1.1 5.6e-16 58.7 1.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel Apelin PF15360.6 GAX27062.1 - 6.5 7.4 7.8 0.8 10.3 1.7 2.6 3 0 0 3 3 3 0 APJ endogenous ligand MS_channel PF00924.18 GAX27063.1 - 9.5e-13 48.2 1.3 1.8e-12 47.2 1.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2207 PF09972.9 GAX27063.1 - 0.065 12.0 2.8 0.11 11.3 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Connexin PF00029.19 GAX27063.1 - 0.082 12.7 2.8 0.5 10.1 0.0 2.4 2 0 0 2 2 2 0 Connexin Mito_carr PF00153.27 GAX27064.1 - 9.6e-07 28.6 1.0 0.0012 18.8 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein Abhydrolase_6 PF12697.7 GAX27065.1 - 3.7e-15 57.1 0.2 8.9e-15 55.9 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX27065.1 - 6.1e-09 35.9 0.5 4e-08 33.2 0.1 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX27065.1 - 0.0025 17.1 0.1 0.11 11.7 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DNA_photolyase PF00875.18 GAX27065.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 DNA photolyase Phage_int_SAM_1 PF02899.17 GAX27067.1 - 0.095 13.0 3.8 0.32 11.3 0.2 2.7 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Afi1 PF07792.12 GAX27068.1 - 0.95 9.9 8.6 0.62 10.5 5.9 2.2 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Asp-B-Hydro_N PF05279.11 GAX27068.1 - 1.8 8.6 11.3 3.8 7.5 11.3 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DNA_pol_A_exo1 PF01612.20 GAX27070.1 - 0.097 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 3'-5' exonuclease YscJ_FliF PF01514.17 GAX27071.1 - 0.081 12.6 0.2 0.27 10.9 0.3 1.7 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family Phage_TAC_1 PF06222.11 GAX27071.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone Fasciclin PF02469.22 GAX27072.1 - 2.6e-63 211.9 0.0 7.4e-20 71.5 0.0 3.1 3 0 0 3 3 3 3 Fasciclin domain RNA_pol_A_bac PF01000.26 GAX27072.1 - 0.06 13.7 0.1 13 6.2 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb3/RpoA insert domain Fasciclin PF02469.22 GAX27073.1 - 3.1e-95 315.2 0.0 6.2e-24 84.6 0.0 4.2 4 0 0 4 4 4 4 Fasciclin domain DUF5089 PF17002.5 GAX27073.1 - 0.37 10.6 3.2 0.58 10.0 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5089) Fasciclin PF02469.22 GAX27074.1 - 3.6e-23 82.2 0.1 3.4e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain PqiA PF04403.13 GAX27075.1 - 6.6e-06 26.0 6.6 6.6e-06 26.0 6.6 2.6 2 0 0 2 2 2 2 Paraquat-inducible protein A DUF4349 PF14257.6 GAX27075.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HSF_DNA-bind PF00447.17 GAX27076.1 - 4.2e-14 52.9 1.5 9.2e-14 51.8 0.5 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding DHDPS PF00701.22 GAX27079.1 - 2.1e-81 272.8 0.0 2.4e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PFK PF00365.20 GAX27080.1 - 6.7e-31 107.7 0.3 3.5e-30 105.3 0.3 1.8 1 1 0 1 1 1 1 Phosphofructokinase HMG_box PF00505.19 GAX27081.1 - 1.2e-08 35.3 5.7 8.4e-08 32.5 5.7 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27081.1 - 2.1e-06 28.2 2.9 2.1e-06 28.2 2.9 2.2 3 0 0 3 3 3 1 HMG-box domain Rep_4 PF05797.11 GAX27082.1 - 0.01 15.0 4.1 0.011 14.9 4.1 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Roughex PF06020.11 GAX27082.1 - 0.46 9.5 11.0 0.56 9.2 11.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein MFS_1_like PF12832.7 GAX27083.1 - 3.4e-56 190.8 12.4 1.2e-55 189.0 12.4 1.8 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAX27083.1 - 1.8e-19 69.9 13.1 2.8e-19 69.3 12.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 GAX27083.1 - 2.5e-15 56.4 8.8 5.7e-11 42.0 2.5 2.2 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 GAX27083.1 - 2e-06 26.8 0.8 2e-06 26.8 0.8 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_4 PF06779.14 GAX27083.1 - 0.00025 20.5 3.1 0.00045 19.6 3.1 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 GAX27083.1 - 0.00049 18.8 9.4 0.0012 17.5 0.4 2.6 1 1 0 2 2 2 2 MFS/sugar transport protein HCO3_cotransp PF00955.21 GAX27084.1 - 2e-108 363.5 20.5 1.6e-69 235.1 1.4 2.7 1 1 0 2 2 2 2 HCO3- transporter family MFS_MOT1 PF16983.5 GAX27084.1 - 2.5 8.5 10.1 3.2 8.2 2.0 3.0 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily WW PF00397.26 GAX27085.1 - 0.0014 18.7 4.3 0.0033 17.5 4.3 1.6 1 0 0 1 1 1 1 WW domain Amino_oxidase PF01593.24 GAX27086.1 - 7.7e-07 28.8 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GAX27086.1 - 1.2e-06 29.0 0.0 0.0014 19.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX27086.1 - 8.9e-06 25.8 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX27086.1 - 0.00013 21.3 0.1 0.00075 18.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX27086.1 - 0.00066 19.0 0.0 0.0015 17.8 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAX27086.1 - 0.0027 17.1 0.7 0.0091 15.4 0.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX27086.1 - 0.0038 16.4 0.2 0.41 9.7 0.1 2.4 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 GAX27086.1 - 0.005 16.0 0.1 0.0092 15.1 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAX27086.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAX27086.1 - 0.12 11.1 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Peptidase_S28 PF05577.12 GAX27087.1 - 3.2e-69 233.8 6.4 5.8e-69 233.0 6.4 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 GAX27087.1 - 0.0023 17.2 0.2 0.0033 16.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 GAX27087.1 - 0.017 14.8 0.8 0.027 14.1 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX27087.1 - 0.027 13.7 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FDF PF09532.10 GAX27088.1 - 0.019 15.8 0.7 0.11 13.4 0.1 2.2 2 0 0 2 2 2 0 FDF domain ATF7IP_BD PF16788.5 GAX27088.1 - 0.089 12.9 1.9 0.13 12.3 1.9 1.4 1 1 0 1 1 1 0 ATF-interacting protein binding domain DUF4130 PF13566.6 GAX27089.1 - 0.029 14.4 0.3 0.029 14.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 Peptidase_M41 PF01434.18 GAX27090.1 - 8.1e-61 205.2 0.0 1.2e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAX27090.1 - 7.1e-43 146.2 0.0 1.9e-42 144.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX27090.1 - 6.1e-14 51.6 0.3 1.5e-13 50.3 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAX27090.1 - 0.00063 20.0 0.1 0.054 13.8 0.1 2.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAX27090.1 - 0.00079 18.7 0.1 0.0022 17.3 0.1 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 GAX27090.1 - 0.0011 19.0 0.6 0.012 15.6 0.0 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAX27090.1 - 0.003 17.3 0.0 0.0087 15.8 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX27090.1 - 0.0037 17.4 0.0 0.0091 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAX27090.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsH_ext PF06480.15 GAX27090.1 - 0.035 14.5 0.0 0.14 12.5 0.0 2.1 1 0 0 1 1 1 0 FtsH Extracellular Mg_chelatase PF01078.21 GAX27090.1 - 0.039 13.3 0.1 0.092 12.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 GAX27090.1 - 0.041 14.0 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAX27090.1 - 0.054 14.0 0.1 0.33 11.5 0.0 2.4 3 0 0 3 3 1 0 AAA domain AAA_28 PF13521.6 GAX27090.1 - 0.099 12.9 1.5 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 GAX27090.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX27090.1 - 0.14 12.5 3.2 0.45 10.9 1.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain Ank_5 PF13857.6 GAX27091.1 - 7.4e-09 35.7 0.3 0.0027 18.0 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX27091.1 - 8.4e-09 35.9 0.0 5e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX27091.1 - 8.9e-05 23.0 0.3 0.029 15.0 0.1 2.8 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX27091.1 - 0.0003 21.0 0.0 0.017 15.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat DUF5536 PF17688.1 GAX27091.1 - 0.008 16.1 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5536) HMG_box PF00505.19 GAX27092.1 - 1.1e-10 41.7 3.3 1.2e-09 38.4 3.3 2.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27092.1 - 3.1e-08 34.1 1.9 8.2e-08 32.7 1.9 1.8 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 GAX27092.1 - 3 8.4 9.2 0.24 11.9 2.3 2.3 2 1 0 2 2 2 0 YABBY protein DUF2457 PF10446.9 GAX27093.1 - 0.0011 18.2 21.6 0.0018 17.5 21.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 GAX27093.1 - 0.0012 19.2 14.9 0.0025 18.1 14.9 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 GAX27093.1 - 0.016 14.6 17.0 0.021 14.2 17.0 1.1 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 GAX27093.1 - 0.029 14.3 6.6 0.043 13.7 6.6 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Cwf_Cwc_15 PF04889.12 GAX27093.1 - 0.089 12.5 26.2 0.17 11.6 26.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.10 GAX27093.1 - 0.13 12.6 4.0 0.23 11.8 4.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LupA PF18242.1 GAX27093.1 - 0.13 11.9 0.3 12 5.5 0.0 3.0 2 1 1 3 3 3 0 Legionella ubiquitin-specific protease A domain TFIIA PF03153.13 GAX27093.1 - 0.24 11.4 14.6 0.35 10.8 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 GAX27093.1 - 0.59 8.2 26.2 0.84 7.7 26.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GAX27093.1 - 1.2 7.4 16.2 4.9 5.3 16.8 1.7 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 GAX27093.1 - 1.3 7.1 23.1 1.7 6.7 23.1 1.1 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 GAX27093.1 - 1.9 7.5 17.3 2.9 6.9 17.3 1.2 1 0 0 1 1 1 0 Pes-10 Tom22 PF04281.13 GAX27093.1 - 1.9 8.2 14.5 4.1 7.2 14.5 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 MRNIP PF15749.5 GAX27093.1 - 3.4 8.4 5.5 8.7 7.1 5.5 1.7 1 0 0 1 1 1 0 MRN-interacting protein Presenilin PF01080.17 GAX27093.1 - 8 5.1 5.3 11 4.7 5.3 1.1 1 0 0 1 1 1 0 Presenilin PAP_fibrillin PF04755.12 GAX27094.1 - 0.0015 18.6 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 PAP_fibrillin RabGAP-TBC PF00566.18 GAX27095.1 - 1.1e-11 44.8 3.2 2.4e-11 43.7 3.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 GAX27096.1 - 3.6e-05 24.2 0.1 0.00051 20.5 0.0 2.7 2 0 0 2 2 2 1 PH domain LRAT PF04970.13 GAX27096.1 - 0.0028 18.0 0.0 0.0066 16.8 0.0 1.6 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Cys_Met_Meta_PP PF01053.20 GAX27097.1 - 1.1e-28 99.9 0.0 2.3e-28 98.8 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 GAX27097.1 - 0.053 12.2 0.0 0.44 9.1 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-III DUF3439 PF11921.8 GAX27097.1 - 0.35 10.8 7.6 0.06 13.3 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) EamA PF00892.20 GAX27098.1 - 6.4e-14 52.3 15.6 1.1e-07 32.1 3.0 3.1 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 GAX27098.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter ABM PF03992.16 GAX27099.1 - 3.5e-14 52.7 0.7 4.7e-14 52.2 0.7 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MFS_3 PF05977.13 GAX27099.1 - 0.03 12.7 0.0 0.032 12.6 0.0 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector S100PBPR PF15427.6 GAX27099.1 - 0.062 12.6 0.1 0.075 12.3 0.1 1.1 1 0 0 1 1 1 0 S100P-binding protein Peptidase_M48 PF01435.18 GAX27100.1 - 1.3e-21 77.3 0.1 2.8e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M78 PF06114.13 GAX27100.1 - 0.086 12.8 0.9 0.37 10.7 0.0 2.5 3 1 0 3 3 3 0 IrrE N-terminal-like domain DUF5010 PF16402.5 GAX27100.1 - 0.093 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) ABC_tran PF00005.27 GAX27101.1 - 1.6e-21 77.3 0.0 3.7e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAX27101.1 - 9.7e-20 70.9 4.3 1.6e-19 70.2 4.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GAX27101.1 - 6.9e-05 22.8 0.1 0.37 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 GAX27101.1 - 0.0007 19.0 1.1 0.0013 18.0 1.1 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 GAX27101.1 - 0.0008 18.9 3.3 0.65 9.4 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 GAX27101.1 - 0.00089 18.5 2.4 0.0014 17.8 2.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RNA_helicase PF00910.22 GAX27101.1 - 0.0018 18.7 0.1 0.82 10.1 0.0 3.5 3 0 0 3 3 3 1 RNA helicase RsgA_GTPase PF03193.16 GAX27101.1 - 0.0022 17.9 0.2 0.0052 16.7 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 GAX27101.1 - 0.0023 17.7 0.1 0.0057 16.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAX27101.1 - 0.0026 18.2 0.0 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAX27101.1 - 0.0062 16.6 0.3 0.013 15.5 0.3 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 GAX27101.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAX27101.1 - 0.043 14.1 1.7 0.47 10.7 0.0 3.3 4 1 1 5 5 5 0 AAA domain AAA_18 PF13238.6 GAX27101.1 - 0.043 14.3 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX27101.1 - 0.09 13.0 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAX27101.1 - 0.1 13.1 0.2 0.1 13.1 0.2 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 GAX27101.1 - 0.11 11.5 0.1 0.38 9.7 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SNARE_assoc PF09335.11 GAX27101.1 - 0.31 11.5 5.4 0.95 10.0 5.4 1.9 1 0 0 1 1 1 0 SNARE associated Golgi protein Peptidase_M41 PF01434.18 GAX27102.1 - 2.1e-60 203.8 0.1 3.9e-60 203.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAX27102.1 - 2.6e-42 144.4 0.0 1.2e-41 142.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX27102.1 - 3.9e-14 52.2 0.3 8.3e-14 51.1 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAX27102.1 - 2.6e-06 27.5 0.2 0.0096 15.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) FtsH_ext PF06480.15 GAX27102.1 - 4.7e-05 23.7 0.1 0.00013 22.2 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 GAX27102.1 - 0.00038 20.8 0.8 0.055 13.8 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAX27102.1 - 0.0013 18.9 0.1 0.0088 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAX27102.1 - 0.0028 16.9 0.1 0.0028 16.9 0.1 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 GAX27102.1 - 0.0033 17.2 0.0 0.0097 15.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAX27102.1 - 0.0088 16.4 3.1 0.073 13.5 1.3 3.3 2 1 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 GAX27102.1 - 0.019 14.7 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad60-SLD PF11976.8 GAX27102.1 - 0.051 13.4 2.0 4.8 7.1 0.4 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like AAA_2 PF07724.14 GAX27102.1 - 0.053 13.6 0.0 0.053 13.6 0.0 3.3 4 2 0 4 4 3 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 GAX27102.1 - 0.058 12.8 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAX27102.1 - 0.06 13.9 0.8 0.32 11.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 GAX27102.1 - 0.11 12.7 0.8 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.26 GAX27103.1 - 2.5e-35 121.7 0.1 3.2e-35 121.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit P5CR_dimer PF14748.6 GAX27104.1 - 6.9e-34 116.2 0.0 1.6e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAX27104.1 - 4.8e-11 43.1 0.0 8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAX27104.1 - 0.00015 21.9 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 GAX27104.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 GAX27104.1 - 0.032 14.7 0.0 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAX27104.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1421 PF07223.11 GAX27104.1 - 0.057 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain (DUF1421) GFO_IDH_MocA PF01408.22 GAX27104.1 - 0.07 14.0 0.1 0.22 12.4 0.1 1.9 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Phage_Coat_Gp8 PF05371.12 GAX27105.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Metallophos PF00149.28 GAX27107.1 - 1.1e-19 71.8 1.1 1.9e-19 71.0 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAX27107.1 - 4.3e-12 46.4 0.3 8.4e-12 45.5 0.3 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GAX27107.1 - 3.8e-10 40.5 0.3 1.7e-09 38.4 0.1 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 GAX27107.1 - 7.9e-06 26.2 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 GAX27107.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Proteasome PF00227.26 GAX27109.1 - 3.5e-59 199.5 0.0 4.1e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX27109.1 - 8.1e-10 38.2 0.1 3.7e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Cyclin_N PF00134.23 GAX27110.1 - 6.2e-18 64.8 0.2 9.7e-18 64.1 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain FAD_binding_3 PF01494.19 GAX27111.1 - 1.4e-24 87.0 0.5 1.2e-10 41.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.12 GAX27111.1 - 1.6e-05 24.2 1.0 0.018 14.1 0.1 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.10 GAX27111.1 - 2.2e-05 23.7 0.1 6.3e-05 22.2 0.1 1.6 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 GAX27111.1 - 4e-05 23.4 0.1 7.9e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAX27111.1 - 0.00039 19.4 0.0 0.067 12.0 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 GAX27111.1 - 0.0028 17.8 0.0 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAX27111.1 - 0.0048 16.2 0.1 0.0083 15.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAX27111.1 - 0.034 13.4 0.1 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 GAX27111.1 - 0.043 12.4 0.1 0.077 11.5 0.1 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 GAX27111.1 - 0.14 12.7 0.1 0.33 11.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX27111.1 - 0.28 10.5 2.1 0.89 8.8 1.4 2.0 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain GATase PF00117.28 GAX27112.1 - 6.8e-11 42.3 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GAX27112.1 - 0.0064 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNF2_N PF00176.23 GAX27113.1 - 6.8e-52 176.3 0.4 1.3e-51 175.4 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pro_isomerase PF00160.21 GAX27113.1 - 4.2e-48 163.6 0.3 8e-48 162.7 0.3 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Helicase_C PF00271.31 GAX27113.1 - 1.2e-05 25.6 0.0 3.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX27113.1 - 0.021 14.8 0.3 1 9.3 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Mitofilin PF09731.9 GAX27114.1 - 0.048 12.5 10.5 0.084 11.7 10.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Telomerase_RBD PF12009.8 GAX27116.1 - 3.2e-26 92.0 3.8 3.2e-26 92.0 3.8 1.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 GAX27116.1 - 4.3e-12 46.0 0.1 2.4e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.15 GAX27117.1 - 4.1e-11 42.8 0.5 7.3e-11 42.0 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAX27117.1 - 0.00014 22.5 0.8 0.0002 22.0 0.8 1.4 1 1 0 1 1 1 1 Complex1_LYR-like MIT PF04212.18 GAX27117.1 - 0.018 15.1 0.5 0.43 10.7 0.0 2.2 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain DUF2521 PF10730.9 GAX27117.1 - 0.054 13.5 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) Bromodomain PF00439.25 GAX27118.1 - 9.6e-23 80.1 0.0 2.9e-22 78.5 0.0 1.7 2 0 0 2 2 2 1 Bromodomain SDA1 PF05285.12 GAX27118.1 - 0.003 17.0 4.8 0.0039 16.7 4.8 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAX27118.1 - 0.034 12.4 8.5 0.039 12.2 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAX27118.1 - 0.043 12.1 3.1 0.048 12.0 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GAX27118.1 - 0.046 12.3 8.0 0.068 11.7 8.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 GAX27118.1 - 0.059 12.7 5.5 0.068 12.5 5.5 1.2 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 GAX27118.1 - 1.2 8.5 15.1 0.75 9.1 13.3 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 GAX27118.1 - 7.7 5.7 11.7 12 5.1 11.7 1.3 1 0 0 1 1 1 0 NOA36 protein Med26 PF08711.11 GAX27119.1 - 1.5e-08 34.5 0.1 4.2e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cupin_4 PF08007.12 GAX27121.1 - 2.2e-31 109.5 1.5 1.4e-30 106.8 1.5 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 GAX27121.1 - 1.1e-06 28.6 0.5 1.3e-05 25.1 0.3 2.2 1 1 0 1 1 1 1 Cupin-like domain Mito_carr PF00153.27 GAX27122.1 - 2.5e-69 229.3 1.7 7.8e-23 80.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX27122.1 - 0.0012 18.0 3.0 0.6 9.2 0.3 3.2 2 1 1 3 3 3 3 Gammaproteobacterial serine protease NUMOD3 PF07460.11 GAX27123.1 - 0.096 12.9 0.6 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) Beach PF02138.18 GAX27124.1 - 2e-116 388.2 0.0 4.2e-116 387.2 0.0 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAX27124.1 - 1.5e-19 69.9 0.0 4.2e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 GAX27124.1 - 4.5e-09 36.0 0.4 3.1e-08 33.2 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) WD40 PF00400.32 GAX27124.1 - 8.6e-06 26.4 7.0 0.51 11.3 0.1 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX27124.1 - 0.024 14.9 0.0 6.1 7.2 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Glycolytic PF00274.19 GAX27124.1 - 0.19 10.4 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I DUF547 PF04784.14 GAX27126.1 - 5.2e-13 49.1 0.0 1.3e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Anoctamin PF04547.12 GAX27127.1 - 1.1e-99 334.3 18.7 1.4e-99 334.0 18.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 GAX27127.1 - 0.0014 18.4 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin UCH PF00443.29 GAX27128.1 - 2.4e-60 204.2 0.0 6.3e-60 202.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX27128.1 - 3.4e-15 56.5 2.6 1.1e-06 28.5 0.0 4.3 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAX27128.1 - 3.7e-14 53.1 0.0 2.7e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 DUSP domain zf-RING_5 PF14634.6 GAX27129.1 - 1.7e-07 31.1 11.4 3.6e-07 30.0 11.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAX27129.1 - 9.7e-07 28.5 12.1 2.3e-06 27.3 12.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX27129.1 - 1.1e-06 28.8 12.1 1.1e-06 28.8 12.1 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX27129.1 - 1.2e-06 28.4 5.8 1.2e-06 28.4 5.8 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX27129.1 - 5.7e-06 26.1 12.3 1.2e-05 25.0 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT_3 PF18428.1 GAX27129.1 - 9.8e-06 25.6 0.3 0.061 13.4 0.1 3.1 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4_4 PF15227.6 GAX27129.1 - 0.00027 21.0 13.2 0.00058 20.0 13.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAX27129.1 - 0.00053 20.0 6.3 0.0012 18.8 6.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAX27129.1 - 0.00057 19.7 8.4 0.0017 18.2 8.4 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAX27129.1 - 0.00094 19.4 5.5 0.0025 18.1 5.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain BRCT_2 PF16589.5 GAX27129.1 - 0.0023 18.3 0.0 2.3 8.7 0.0 2.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAX27129.1 - 0.02 15.3 0.0 8.4 6.9 0.0 3.2 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain zf-Nse PF11789.8 GAX27129.1 - 0.079 12.8 5.8 0.21 11.4 5.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAX27129.1 - 0.1 12.5 15.9 0.47 10.4 15.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 GAX27129.1 - 1 9.3 11.1 3.6 7.5 11.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX27129.1 - 1.3 8.7 9.1 2.7 7.7 9.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 GAX27129.1 - 3.3 7.6 5.5 30 4.6 0.2 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif Trypsin_2 PF13365.6 GAX27130.1 - 1.4e-25 90.9 0.1 4.2e-25 89.4 0.1 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX27130.1 - 1.8e-09 37.7 0.1 5.8e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Trypsin PDZ_2 PF13180.6 GAX27130.1 - 6.9e-07 29.5 0.0 1.9e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 PDZ domain Peptidase_S29 PF02907.15 GAX27130.1 - 0.00072 19.3 0.1 0.0019 17.9 0.1 1.7 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.21 GAX27130.1 - 0.0013 18.6 0.3 0.0037 17.1 0.3 1.7 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 GAX27130.1 - 0.0071 15.9 0.7 2 7.9 0.0 2.5 3 0 0 3 3 3 2 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 GAX27130.1 - 0.022 13.4 0.1 0.037 12.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase S46 PDZ_6 PF17820.1 GAX27130.1 - 0.023 14.5 0.0 7.1 6.6 0.0 2.7 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.24 GAX27130.1 - 0.032 14.6 0.0 0.088 13.2 0.0 1.8 1 0 0 1 1 1 0 PDZ domain GTP_EFTU PF00009.27 GAX27131.1 - 4.1e-48 163.5 0.0 6e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 GAX27131.1 - 3.3e-41 140.2 0.0 6.1e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 GAX27131.1 - 2.4e-05 24.6 0.0 4.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAX27131.1 - 4.7e-05 23.4 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAX27131.1 - 6.4e-05 23.0 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FemAB PF02388.16 GAX27133.1 - 7 5.4 7.5 11 4.7 7.5 1.2 1 0 0 1 1 1 0 FemAB family Ceramidase PF05875.12 GAX27135.1 - 9.2e-32 110.5 8.8 1.3e-31 110.0 8.8 1.2 1 0 0 1 1 1 1 Ceramidase Ank_2 PF12796.7 GAX27136.1 - 9.4e-07 29.3 2.5 0.0017 18.9 0.5 3.1 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX27136.1 - 6.6e-06 26.6 5.7 0.042 14.4 0.2 5.3 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX27136.1 - 1.1e-05 25.3 7.7 3.9 8.3 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAX27136.1 - 0.0021 18.3 2.5 0.079 13.3 0.5 4.0 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX27136.1 - 0.028 14.8 6.7 1.2 9.7 0.2 4.1 5 0 0 5 5 5 0 Ankyrin repeat MARVEL PF01284.23 GAX27137.1 - 0.0019 18.2 35.8 0.033 14.2 13.9 3.3 1 1 2 3 3 3 1 Membrane-associating domain Astro_capsid_p PF12226.8 GAX27137.1 - 0.66 9.1 4.1 1.1 8.4 4.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Choline_transpo PF04515.12 GAX27138.1 - 8.8e-58 196.0 20.9 8.8e-58 196.0 20.9 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter FTHFS PF01268.19 GAX27139.1 - 1.5e-250 832.2 0.5 1.7e-250 832.0 0.5 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 GAX27139.1 - 0.013 15.5 0.7 0.039 14.0 0.4 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3611 PF12263.8 GAX27140.1 - 1.7e-38 132.3 9.5 2.3e-38 131.9 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) DUF4395 PF14340.6 GAX27140.1 - 0.044 14.1 2.7 0.2 12.0 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) PWI PF01480.17 GAX27141.1 - 3.7e-07 30.3 0.3 6.2e-07 29.6 0.3 1.4 1 0 0 1 1 1 1 PWI domain Phenol_monoox PF04663.12 GAX27141.1 - 0.22 11.7 0.6 0.75 10.0 0.1 2.1 2 0 0 2 2 2 0 Phenol hydroxylase conserved region DUF4611 PF15387.6 GAX27141.1 - 7.4 6.9 8.4 39 4.5 0.3 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) DUF839 PF05787.13 GAX27142.1 - 0.0015 17.8 2.3 0.0064 15.7 0.0 2.6 2 1 0 3 3 3 1 Bacterial protein of unknown function (DUF839) MFS_2 PF13347.6 GAX27142.1 - 0.12 10.9 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein OAD_gamma PF04277.13 GAX27142.1 - 0.17 12.5 0.3 0.33 11.6 0.3 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF839 PF05787.13 GAX27143.1 - 4.3e-12 46.0 2.6 7.2e-08 32.0 1.1 2.4 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF839) Elf1 PF05129.13 GAX27144.1 - 3.4e-27 94.3 1.1 4.9e-27 93.8 1.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like CcmH PF03918.14 GAX27144.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Lar_restr_allev PF14354.6 GAX27144.1 - 0.5 10.8 4.8 1.6 9.1 4.8 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.15 GAX27144.1 - 1.7 8.8 5.1 8.5 6.5 0.7 2.6 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger SRRM_C PF15230.6 GAX27145.1 - 0.15 12.7 2.9 0.36 11.4 2.9 1.6 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus DUF4164 PF13747.6 GAX27145.1 - 0.54 10.6 3.4 2.9 8.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Mito_carr PF00153.27 GAX27148.1 - 4.3e-52 174.0 1.0 4.4e-18 65.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mit_KHE1 PF10173.9 GAX27148.1 - 0.039 14.0 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related HisKA_7TM PF16927.5 GAX27149.1 - 0.072 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase LRR_4 PF12799.7 GAX27150.1 - 6.2e-10 39.2 6.0 0.038 14.4 0.0 5.5 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX27150.1 - 6.9e-08 32.1 5.3 0.00014 21.5 0.0 3.7 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 GAX27150.1 - 0.0014 18.9 0.1 50 5.0 0.0 5.4 5 1 0 5 5 5 1 Leucine Rich Repeat TLD PF07534.16 GAX27151.1 - 1.9e-05 24.9 0.0 2.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 TLD RVT_2 PF07727.14 GAX27152.1 - 3.5e-08 33.4 0.0 5.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF563 PF04577.14 GAX27153.1 - 0.0064 16.6 0.0 0.013 15.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) COG4 PF08318.12 GAX27154.1 - 0.013 14.6 0.1 0.056 12.5 0.0 1.9 1 1 0 1 1 1 0 COG4 transport protein E1_dh PF00676.20 GAX27155.1 - 3.7e-98 328.2 0.2 4.3e-98 328.0 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAX27155.1 - 0.0036 16.6 0.2 0.0099 15.1 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase MMR_HSR1 PF01926.23 GAX27156.1 - 5.9e-18 65.0 0.0 1.8e-16 60.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX27156.1 - 5e-07 29.4 0.1 1.1e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 GAX27156.1 - 0.00047 19.2 2.2 0.012 14.6 0.1 2.3 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 GAX27156.1 - 0.011 15.1 0.0 0.034 13.5 0.0 1.8 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 GAX27156.1 - 0.011 15.7 2.4 0.019 15.1 0.1 2.4 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 GAX27156.1 - 0.018 14.6 0.1 4.9 6.6 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Peripla_BP_3 PF13377.6 GAX27156.1 - 0.023 15.0 0.1 0.21 11.9 0.0 2.4 3 1 1 4 4 4 0 Periplasmic binding protein-like domain SRPRB PF09439.10 GAX27156.1 - 0.023 14.1 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arabinose_Isome PF02610.15 GAX27156.1 - 0.027 13.7 0.7 0.039 13.2 0.7 1.1 1 0 0 1 1 1 0 L-arabinose isomerase RsgA_GTPase PF03193.16 GAX27156.1 - 0.038 13.9 0.4 0.12 12.3 0.1 1.9 2 1 0 3 3 3 0 RsgA GTPase Roc PF08477.13 GAX27156.1 - 0.039 14.2 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GDPD PF03009.17 GAX27159.1 - 1.2e-13 51.4 0.0 6.1e-13 49.1 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Kelch_3 PF13415.6 GAX27160.1 - 2e-14 53.4 11.9 3e-05 24.2 0.0 6.4 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 GAX27160.1 - 1.3e-12 47.6 6.4 0.0068 16.4 0.0 6.1 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAX27160.1 - 1.8e-11 43.7 0.0 0.036 14.0 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GAX27160.1 - 9.5e-11 41.6 4.5 0.036 14.4 0.0 5.3 2 2 3 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAX27160.1 - 1.2e-05 25.1 0.0 2.4 8.3 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 GAX27160.1 - 0.00025 20.6 4.9 0.14 11.8 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Arm PF00514.23 GAX27161.1 - 2.9e-11 43.0 2.4 1.8e-05 24.6 0.0 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 GAX27161.1 - 0.00012 22.0 0.3 0.01 15.9 0.4 3.3 1 1 2 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 GAX27161.1 - 0.0053 16.9 1.6 5 7.6 0.0 3.8 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 GAX27161.1 - 0.045 14.3 0.4 11 6.6 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat DNA_pol_B_palm PF14792.6 GAX27162.1 - 3.2e-18 66.0 0.0 2.2e-16 60.1 0.0 2.7 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 GAX27162.1 - 3.2e-13 49.6 0.0 8.7e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GAX27162.1 - 1.4e-11 44.0 0.0 7.2e-11 41.7 0.0 2.3 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.23 GAX27162.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_8 PF14716.6 GAX27162.1 - 0.003 17.9 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 GAX27162.1 - 0.0086 16.7 0.0 0.28 11.8 0.0 3.2 4 0 0 4 4 4 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 GAX27163.1 - 1.8e-18 66.8 0.0 8.9e-17 61.3 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 GAX27163.1 - 1e-15 57.6 0.1 2.3e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GAX27163.1 - 7.7e-11 41.7 0.0 4e-10 39.4 0.0 2.3 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 GAX27163.1 - 1.2e-07 32.0 0.0 2.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 GAX27163.1 - 0.0074 16.9 0.0 1.7 9.3 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 GAX27163.1 - 0.01 16.1 0.0 0.039 14.3 0.0 2.0 1 0 0 1 1 1 0 Nucleotidyltransferase domain Caudo_bapla16 PF16792.5 GAX27163.1 - 0.037 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Phage tail base-plate attachment protein of Caudovirales ORF16 Hydantoinase_B PF02538.14 GAX27164.1 - 1.7e-211 703.1 0.5 2.2e-211 702.8 0.5 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAX27164.1 - 1.8e-100 336.0 0.0 3.7e-100 335.0 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAX27164.1 - 3.4e-54 183.2 0.0 3.6e-52 176.7 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region STAS PF01740.21 GAX27165.1 - 8.1e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 GAX27165.1 - 9.8e-09 34.4 7.2 0.0001 21.2 2.9 2.4 2 0 0 2 2 2 2 Sulfate permease family STAS_2 PF13466.6 GAX27165.1 - 0.0015 18.8 0.0 0.0047 17.2 0.0 1.9 1 0 0 1 1 1 1 STAS domain NAD_binding_1 PF00175.21 GAX27166.1 - 2.6e-21 76.3 0.0 5.2e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX27166.1 - 0.0011 19.3 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain E1-E2_ATPase PF00122.20 GAX27167.1 - 3.2e-48 163.6 0.8 1.2e-47 161.8 0.7 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAX27167.1 - 4e-15 56.7 0.7 2.3e-14 54.2 0.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX27167.1 - 3.5e-11 42.6 0.1 1.7e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX27167.1 - 0.00045 20.1 0.6 0.0011 18.7 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX27167.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2975 PF11188.8 GAX27167.1 - 0.1 12.5 11.9 0.83 9.5 2.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) bZIP_1 PF00170.21 GAX27168.1 - 1.7e-11 44.0 12.9 2.3e-11 43.6 12.9 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX27168.1 - 3.2e-08 33.5 14.9 4.7e-08 33.0 14.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAX27168.1 - 6.9e-05 23.3 5.7 9.7e-05 22.8 5.7 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor BTAD PF03704.17 GAX27168.1 - 0.002 18.6 0.3 0.0029 18.1 0.3 1.2 1 0 0 1 1 1 1 Bacterial transcriptional activator domain NRBF2 PF08961.10 GAX27168.1 - 0.024 14.3 2.4 0.033 13.8 2.4 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 GAX27168.1 - 0.046 14.4 0.1 0.051 14.2 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA GIT_CC PF16559.5 GAX27168.1 - 0.068 13.0 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor LMBR1 PF04791.16 GAX27168.1 - 0.12 11.2 0.1 0.13 11.1 0.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Tho2 PF11262.8 GAX27168.1 - 0.31 10.2 1.7 0.37 9.9 1.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CDC45 PF02724.14 GAX27168.1 - 0.57 8.4 7.3 0.65 8.2 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein XAP5 PF04921.14 GAX27168.1 - 0.66 9.8 7.4 0.82 9.4 7.4 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator SGT1 PF07093.11 GAX27168.1 - 6 5.2 6.5 7 5.0 6.5 1.1 1 0 0 1 1 1 0 SGT1 protein LRR_4 PF12799.7 GAX27171.1 - 5.1e-16 58.5 15.7 0.00033 21.0 1.5 5.5 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX27171.1 - 2.3e-11 43.3 19.3 5.5e-07 29.3 8.1 4.7 3 2 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 GAX27171.1 - 4.1e-09 35.7 12.7 0.17 12.6 0.1 7.4 6 2 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.6 GAX27171.1 - 7.7 6.8 11.2 52 4.3 0.4 5.1 5 0 0 5 5 5 0 Leucine Rich repeat DUF2428 PF10350.9 GAX27172.1 - 1.8e-31 109.4 0.2 3.7e-31 108.4 0.2 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 GAX27172.1 - 2e-11 43.1 2.0 0.0052 16.9 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 GAX27172.1 - 4.8e-09 36.5 6.8 0.032 14.6 0.0 7.4 7 1 1 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 GAX27172.1 - 2.9e-06 27.6 6.7 0.0026 18.3 0.1 5.3 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 GAX27172.1 - 0.0028 17.6 0.6 0.14 12.3 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Lipase_GDSL_2 PF13472.6 GAX27173.1 - 3.4e-12 47.1 0.0 8.4e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX27173.1 - 1.6e-08 34.7 0.0 2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MBG_2 PF18676.1 GAX27173.1 - 0.085 13.5 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 MBG domain (YGX type) Ion_trans_2 PF07885.16 GAX27174.1 - 4.1e-19 68.3 18.1 1.1e-10 41.4 4.9 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 GAX27174.1 - 0.00022 20.5 8.4 0.028 13.6 0.1 2.1 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 GAX27174.1 - 0.081 12.7 3.5 0.98 9.2 0.6 2.3 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain MafB19-deam PF14437.6 GAX27175.1 - 3.1e-20 72.3 0.0 3.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 GAX27175.1 - 1.4e-17 63.4 0.7 3.4e-17 62.2 0.7 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 GAX27175.1 - 0.00025 21.2 0.2 0.00043 20.4 0.2 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 GAX27175.1 - 0.00031 20.7 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 GAX27175.1 - 0.0032 17.6 0.0 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 GAX27175.1 - 0.0081 16.2 0.1 0.01 15.9 0.1 1.2 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 GAX27175.1 - 0.038 14.1 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 GAX27175.1 - 0.058 13.5 0.1 0.097 12.8 0.1 1.4 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 GAX27175.1 - 0.07 13.2 2.0 0.12 12.4 2.0 1.4 1 1 0 1 1 1 0 Bd3614-like deaminase Na_Ca_ex PF01699.24 GAX27176.1 - 1.2e-35 122.8 43.5 2e-20 73.3 17.0 3.4 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF2678 PF10856.8 GAX27176.1 - 0.00049 20.0 0.4 0.0018 18.2 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) SpoOE-like PF09388.10 GAX27177.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein DUF1285 PF06938.11 GAX27177.1 - 0.22 11.6 1.7 1.8 8.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1285) Med3 PF11593.8 GAX27178.1 - 0.029 13.6 0.9 0.033 13.4 0.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LZ_Tnp_IS66 PF13007.7 GAX27178.1 - 0.098 13.4 1.7 0.26 12.1 1.7 1.8 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain Methyltransf_22 PF13383.6 GAX27179.1 - 2.9e-89 299.0 0.5 3.3e-89 298.8 0.5 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 GAX27179.1 - 0.0021 18.1 0.1 0.0036 17.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain Pro_isomerase PF00160.21 GAX27180.1 - 4.9e-50 169.9 0.2 5.7e-50 169.7 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TatD_DNase PF01026.21 GAX27181.1 - 3.7e-30 105.1 0.1 4.5e-30 104.9 0.1 1.0 1 0 0 1 1 1 1 TatD related DNase CPBP PF02517.16 GAX27182.1 - 1.9e-13 50.6 1.6 6.7e-13 48.8 1.4 2.0 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease DUF3854 PF12965.7 GAX27182.1 - 0.044 13.7 0.1 9.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) EF-hand_7 PF13499.6 GAX27182.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair His_Phos_1 PF00300.22 GAX27183.1 - 2.8e-16 59.8 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MutS_V PF00488.21 GAX27184.1 - 1.2e-29 103.7 0.1 3.3e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 GAX27184.1 - 3.2e-26 92.8 0.5 5.6e-26 91.9 0.5 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAX27184.1 - 0.00018 21.8 0.0 0.00042 20.6 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV ABC_tran PF00005.27 GAX27185.1 - 1.3e-30 106.7 0.8 4e-15 56.5 0.0 3.4 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAX27185.1 - 4.8e-13 49.6 4.5 0.0011 18.9 0.0 4.7 3 2 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX27185.1 - 5.7e-09 35.7 1.5 4.5e-07 29.5 1.5 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAX27185.1 - 2e-08 34.4 0.0 1.1e-05 25.4 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 GAX27185.1 - 5.2e-08 33.6 11.8 0.0017 18.9 1.4 4.0 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAX27185.1 - 5.3e-07 30.2 4.9 0.014 15.8 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAX27185.1 - 2e-06 27.4 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 GAX27185.1 - 2.6e-06 27.5 0.1 1.9 8.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAX27185.1 - 6.5e-06 26.0 0.0 0.8 9.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 GAX27185.1 - 7.2e-06 26.0 0.0 0.0062 16.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 GAX27185.1 - 9.1e-06 26.1 4.5 0.2 12.1 0.1 4.5 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAX27185.1 - 4.2e-05 23.8 5.7 0.87 9.9 0.1 4.9 2 2 1 3 3 3 2 AAA domain TsaE PF02367.17 GAX27185.1 - 0.00044 20.2 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 GAX27185.1 - 0.00049 18.9 9.9 0.5 9.0 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_28 PF13521.6 GAX27185.1 - 0.0013 19.0 0.5 1.2 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 GAX27185.1 - 0.0014 18.0 0.0 6.5 6.1 0.0 3.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX27185.1 - 0.0016 18.6 1.7 1.4 9.1 0.0 3.9 3 2 0 3 3 3 1 AAA domain AAA_24 PF13479.6 GAX27185.1 - 0.0019 18.0 0.3 2.9 7.6 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_7 PF12775.7 GAX27185.1 - 0.0025 17.3 0.0 0.37 10.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GAX27185.1 - 0.0031 17.9 0.0 0.45 10.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_11 PF13086.6 GAX27185.1 - 0.0036 17.1 8.0 0.0083 15.9 2.1 3.3 3 1 0 4 4 4 1 AAA domain RuvB_N PF05496.12 GAX27185.1 - 0.0041 16.9 1.4 0.066 13.0 0.0 3.3 3 1 1 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 GAX27185.1 - 0.0051 16.6 0.1 3 7.6 0.0 2.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 GAX27185.1 - 0.0061 16.3 0.1 0.52 10.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain NTPase_1 PF03266.15 GAX27185.1 - 0.011 15.6 1.0 2.7 7.9 0.1 4.1 5 0 0 5 5 4 0 NTPase RsgA_GTPase PF03193.16 GAX27185.1 - 0.012 15.6 0.1 3.6 7.5 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 GAX27185.1 - 0.019 15.2 0.0 14 6.0 0.0 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 GAX27185.1 - 0.029 14.6 0.0 0.099 12.9 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAX27185.1 - 0.031 14.8 1.1 3.4 8.2 0.0 3.4 3 1 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 GAX27185.1 - 0.041 13.2 1.7 2.3 7.5 0.0 3.3 4 0 0 4 4 3 0 Zeta toxin DNA_pol3_delta2 PF13177.6 GAX27185.1 - 0.052 13.3 0.0 0.66 9.7 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III, delta subunit TIR-like PF10137.9 GAX27185.1 - 0.088 12.8 0.1 0.39 10.7 0.0 2.1 2 0 0 2 2 1 0 Predicted nucleotide-binding protein containing TIR-like domain HlyD_2 PF12700.7 GAX27185.1 - 0.71 8.5 10.5 0.14 10.9 3.4 2.1 2 0 0 2 2 2 0 HlyD family secretion protein Caps_synth_GfcC PF06251.11 GAX27185.1 - 0.87 9.2 4.0 0.37 10.4 1.2 1.9 2 0 0 2 2 2 0 Capsule biosynthesis GfcC DUF2120 PF09893.9 GAX27185.1 - 6.5 6.9 6.9 0.51 10.4 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF883 PF05957.13 GAX27185.1 - 8.3 7.1 11.9 4.1 8.1 6.9 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PEP_mutase PF13714.6 GAX27186.1 - 0.051 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Xan_ur_permease PF00860.20 GAX27187.1 - 1.6e-62 211.5 27.0 3.2e-42 144.6 12.1 2.1 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 GAX27187.1 - 0.0015 17.3 5.6 0.0015 17.3 5.6 1.8 2 1 0 2 2 2 1 Sulfate permease family dCMP_cyt_deam_1 PF00383.23 GAX27188.1 - 7.6e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX27188.1 - 2.7e-05 23.9 0.0 4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAX27188.1 - 0.067 13.3 0.2 0.11 12.5 0.2 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase UpxZ PF06603.11 GAX27189.1 - 0.06 13.6 0.4 5.6 7.3 0.1 2.6 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists DUF434 PF04256.12 GAX27189.1 - 0.074 12.7 0.0 0.29 10.9 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Laminin_I PF06008.14 GAX27189.1 - 0.67 9.6 8.6 1.3 8.7 8.6 1.4 1 0 0 1 1 1 0 Laminin Domain I PTS_IIA PF02255.16 GAX27189.1 - 2.2 8.4 5.4 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Wx5_PLAF3D7 PF09688.10 GAX27189.1 - 3 7.8 5.7 2.6 8.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (Wx5_PLAF3D7) Abhydrolase_1 PF00561.20 GAX27190.1 - 2.5e-12 47.0 0.0 4.1e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX27190.1 - 2e-07 31.8 1.8 1.2e-06 29.3 1.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX27190.1 - 4.8e-05 22.7 0.1 0.25 10.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 GAX27190.1 - 0.0019 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF1057 PF06342.12 GAX27190.1 - 0.0051 15.9 0.0 0.0074 15.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 GAX27190.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.10 GAX27190.1 - 0.02 15.0 0.0 0.38 10.9 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein Peptidase_S9 PF00326.21 GAX27190.1 - 0.022 14.2 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 GAX27190.1 - 0.056 13.0 0.0 6 6.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF915 PF06028.11 GAX27190.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 GAX27190.1 - 0.1 12.1 0.0 1.6 8.2 0.0 2.0 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 GAX27190.1 - 0.11 12.3 0.0 0.59 9.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAX27190.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 GAX27190.1 - 0.19 11.6 0.0 1.2 9.1 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 GAX27190.1 - 0.2 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Cyt-b5 PF00173.28 GAX27191.1 - 1.2e-19 70.2 0.2 2e-19 69.5 0.2 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4366 PF14283.6 GAX27191.1 - 0.074 13.1 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SNARE PF05739.19 GAX27191.1 - 0.13 12.2 0.1 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 SNARE domain FCD PF07729.12 GAX27192.1 - 0.072 13.5 1.3 0.26 11.7 0.8 2.1 2 0 0 2 2 2 0 FCD domain 7TMR-HDED PF07697.11 GAX27192.1 - 0.43 10.7 3.6 1.1 9.3 3.6 1.7 1 0 0 1 1 1 0 7TM-HD extracellular Cornifin PF02389.15 GAX27194.1 - 0.0025 18.0 3.7 0.0025 18.0 1.5 2.0 1 1 1 2 2 2 1 Cornifin (SPRR) family eIF3_subunit PF08597.10 GAX27194.1 - 3.8 7.3 25.2 0.39 10.6 17.1 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Beta_elim_lyase PF01212.21 GAX27195.1 - 2.3e-28 99.3 0.0 2.8e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase AbfB PF05270.13 GAX27195.1 - 0.01 15.8 0.1 0.1 12.6 0.0 2.1 1 1 1 2 2 2 0 Alpha-L-arabinofuranosidase B (ABFB) domain DUF3246 PF11596.8 GAX27196.1 - 0.0018 17.8 0.4 0.0021 17.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) DUF5351 PF17302.2 GAX27196.1 - 0.0054 16.9 14.5 0.23 11.7 1.1 3.7 2 1 1 3 3 3 3 Family of unknown function (DUF5351) CENP-B_dimeris PF09026.10 GAX27196.1 - 0.28 11.6 2.5 0.45 10.9 2.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UDPGP PF01704.18 GAX27197.1 - 5.2e-20 71.5 0.0 9.5e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ala_racemase_N PF01168.20 GAX27198.1 - 7.6e-25 87.9 0.0 9.8e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Inj_translocase PF16928.5 GAX27198.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome RPN13_C PF16550.5 GAX27199.1 - 3.9e-20 72.1 1.2 4.2e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 UCH-binding domain Proteasom_Rpn13 PF04683.13 GAX27199.1 - 1.6e-07 31.7 0.8 3e-07 30.9 0.8 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor AnfG_VnfG PF03139.15 GAX27199.1 - 0.11 12.6 1.3 0.21 11.7 1.3 1.4 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Ndc1_Nup PF09531.10 GAX27199.1 - 0.28 9.8 0.6 0.36 9.5 0.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SET PF00856.28 GAX27200.1 - 3.3e-06 27.6 0.0 0.0011 19.4 0.0 3.1 2 1 0 2 2 2 1 SET domain Cyclin_N PF00134.23 GAX27201.1 - 3.3e-11 43.0 0.0 5.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX27201.1 - 0.003 17.6 0.1 0.0055 16.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Nse4_C PF08743.10 GAX27203.1 - 1.1e-16 60.8 0.1 3.3e-15 56.1 0.0 2.7 2 0 0 2 2 2 1 Nse4 C-terminal Cyclin_N PF00134.23 GAX27205.1 - 1.4e-11 44.2 0.3 1.5e-10 40.9 0.3 2.1 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX27205.1 - 0.00076 19.6 0.1 0.0017 18.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain AhpC-TSA_2 PF13911.6 GAX27206.1 - 7.9e-11 42.1 0.1 1.3e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 GAX27206.1 - 0.031 14.0 0.0 0.084 12.6 0.0 1.7 2 0 0 2 2 2 0 Redoxin NAD_binding_1 PF00175.21 GAX27206.1 - 0.084 13.5 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain HEAT PF02985.22 GAX27207.1 - 7.2e-20 69.4 26.1 2.1e-05 24.4 0.2 11.9 13 0 0 13 13 12 6 HEAT repeat HEAT_EZ PF13513.6 GAX27207.1 - 2.9e-18 66.0 42.0 1.8e-05 25.1 0.7 13.0 11 2 2 13 13 13 7 HEAT-like repeat HEAT_2 PF13646.6 GAX27207.1 - 6.9e-15 55.2 16.7 0.0032 17.8 0.2 10.2 7 3 4 11 11 11 5 HEAT repeats Vac14_Fab1_bd PF12755.7 GAX27207.1 - 1.1e-12 48.4 0.1 0.00052 20.6 0.0 6.5 6 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region UME PF08064.13 GAX27207.1 - 4.1e-10 39.5 0.6 0.83 9.6 0.0 7.8 6 2 1 7 7 7 2 UME (NUC010) domain CLASP_N PF12348.8 GAX27207.1 - 3.8e-09 36.5 0.3 0.1 12.1 0.0 5.9 6 0 0 6 6 6 2 CLASP N terminal Cnd1 PF12717.7 GAX27207.1 - 9.1e-09 35.6 0.0 0.00084 19.4 0.0 4.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAX27207.1 - 2.3e-05 23.1 0.1 0.006 15.2 0.0 3.3 3 0 0 3 3 3 1 Adaptin N terminal region TIP120 PF08623.10 GAX27207.1 - 3.9e-05 23.5 0.0 0.97 9.2 0.0 4.3 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 GAX27207.1 - 5.2e-05 23.2 0.0 17 5.3 0.0 6.1 4 2 2 7 7 7 0 Domain of unknown function (DUF3385) Tti2 PF10521.9 GAX27207.1 - 7.2e-05 22.5 0.0 0.11 12.1 0.0 4.0 5 1 1 6 6 6 1 Tti2 family Importin_rep_4 PF18808.1 GAX27207.1 - 0.00014 22.0 4.7 0.0027 18.0 0.1 3.6 3 0 0 3 3 3 1 Importin repeat IBN_N PF03810.19 GAX27207.1 - 0.00059 19.7 1.5 0.0033 17.3 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 GAX27207.1 - 0.023 14.9 0.0 4.3 7.5 0.0 3.9 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-MYND PF01753.18 GAX27208.1 - 3.9e-06 26.8 18.4 5.8e-06 26.3 18.4 1.3 1 0 0 1 1 1 1 MYND finger DUF2237 PF09996.9 GAX27208.1 - 0.033 14.2 0.2 0.055 13.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) Amastin PF07344.11 GAX27208.1 - 0.17 11.7 1.4 0.28 11.0 1.4 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein THF_DHG_CYH_C PF02882.19 GAX27209.1 - 6.1e-63 210.9 0.4 1.1e-62 210.1 0.4 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAX27209.1 - 1.6e-42 144.5 0.3 2.4e-42 143.9 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 GAX27209.1 - 0.0035 16.3 0.2 0.0057 15.6 0.2 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AlaDh_PNT_C PF01262.21 GAX27209.1 - 0.027 13.8 2.5 0.1 11.9 2.3 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 GAX27209.1 - 0.094 13.2 0.9 0.23 11.9 0.3 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding PAP_fibrillin PF04755.12 GAX27211.1 - 2.3e-06 27.7 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin Myosin_head PF00063.21 GAX27212.1 - 1.6e-204 681.0 0.1 3.5e-204 679.9 0.1 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 GAX27212.1 - 0.001 19.5 0.0 0.0037 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 GAX27212.1 - 0.0015 17.7 0.1 0.0026 16.9 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 GAX27212.1 - 0.0015 18.8 0.1 0.0043 17.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX27212.1 - 0.015 15.7 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 GAX27212.1 - 0.019 13.9 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF3987 PF13148.6 GAX27212.1 - 0.026 13.6 0.4 0.049 12.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Sigma54_activat PF00158.26 GAX27212.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Ribosomal_S19 PF00203.21 GAX27213.1 - 4.7e-31 106.5 0.1 6.3e-31 106.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 GAX27213.1 - 0.0018 18.3 0.0 0.0024 17.9 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH DEAD PF00270.29 GAX27214.1 - 2.7e-41 141.3 0.0 7.6e-41 139.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX27214.1 - 4.3e-27 94.6 0.0 5.3e-26 91.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 GAX27214.1 - 1.2e-10 41.5 5.5 1.2e-10 41.5 5.5 2.9 2 0 0 2 2 2 1 DBP10CT (NUC160) domain AAA_22 PF13401.6 GAX27214.1 - 0.14 12.5 0.0 0.92 9.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain Ribosomal_S9 PF00380.19 GAX27214.1 - 2.5 8.6 9.9 1.9 9.0 7.7 1.9 2 0 0 2 2 2 0 Ribosomal protein S9/S16 Cupin_8 PF13621.6 GAX27215.1 - 3.2e-12 46.7 0.0 2.7e-11 43.7 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 GAX27215.1 - 1.8e-05 25.1 0.0 0.00019 21.8 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Chromo PF00385.24 GAX27215.1 - 0.00036 20.4 0.1 0.00096 19.0 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DEK_C PF08766.11 GAX27216.1 - 0.017 15.0 0.3 0.059 13.3 0.1 2.0 2 0 0 2 2 2 0 DEK C terminal domain DUF3944 PF13099.6 GAX27216.1 - 0.042 13.7 0.2 24 4.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3944) tRNA_int_end_N2 PF12928.7 GAX27217.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term ECH_2 PF16113.5 GAX27218.1 - 3.1e-21 76.2 0.1 4.3e-10 39.6 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAX27218.1 - 0.15 11.4 0.0 0.57 9.4 0.0 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase HOOK PF05622.12 GAX27219.1 - 2.4e-44 151.6 63.3 2.6e-40 138.3 54.7 3.0 1 1 1 2 2 2 2 HOOK protein CdvA PF18822.1 GAX27219.1 - 0.0035 17.2 10.1 0.0035 17.2 10.1 5.5 4 2 2 6 6 6 2 CdvA-like coiled-coil domain MAD PF05557.13 GAX27219.1 - 0.0094 14.4 61.7 0.065 11.6 37.3 2.2 2 0 0 2 2 2 2 Mitotic checkpoint protein BLOC1_2 PF10046.9 GAX27219.1 - 0.018 15.3 7.3 0.018 15.3 7.3 6.4 2 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.6 GAX27219.1 - 0.59 9.8 63.4 0.088 12.5 26.0 4.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 GAX27219.1 - 1.3 9.0 79.8 0.28 11.2 16.2 5.2 2 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 GAX27219.1 - 1.9 9.0 87.4 3.5 8.2 22.6 4.8 2 1 2 4 4 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 GAX27219.1 - 1.9 8.6 70.0 0.52 10.4 19.0 4.4 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DASH_Dam1 PF08653.10 GAX27219.1 - 2.6 7.9 7.4 15 5.4 0.3 4.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 Golgin_A5 PF09787.9 GAX27219.1 - 2.8 7.3 63.6 0.52 9.7 13.9 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 GAX27219.1 - 3.6 7.6 29.4 0.13 12.3 4.9 4.1 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 GAX27219.1 - 4.2 7.6 71.6 1.5 9.1 10.6 5.8 2 2 4 6 6 6 0 TATA element modulatory factor 1 TATA binding RasGAP_C PF03836.15 GAX27219.1 - 4.5 7.4 41.5 0.027 14.6 10.5 4.0 2 1 1 3 3 3 0 RasGAP C-terminus HMMR_N PF15905.5 GAX27219.1 - 4.8 6.6 75.1 1.1 8.6 41.7 3.7 2 2 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Peptidase_C10 PF01640.17 GAX27219.1 - 5.3 7.3 8.7 32 4.8 3.6 2.9 2 1 0 2 2 2 0 Peptidase C10 family Atg14 PF10186.9 GAX27219.1 - 7 5.6 64.4 0.13 11.3 18.1 3.4 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_porin PF12795.7 GAX27219.1 - 7 6.1 74.9 2.8 7.4 11.6 4.1 1 1 3 4 4 4 0 Mechanosensitive ion channel porin domain ATP-synt_C PF00137.21 GAX27220.1 - 1.2e-28 99.3 28.5 3.5e-15 56.1 9.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 GAX27220.1 - 0.16 11.3 1.6 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Thioredoxin_8 PF13905.6 GAX27221.1 - 0.00068 19.9 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 GAX27221.1 - 0.0078 16.2 0.3 0.015 15.2 0.3 1.5 1 0 0 1 1 1 1 Thioredoxin DUF2688 PF10892.8 GAX27221.1 - 0.074 12.5 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) cIII PF08134.11 GAX27223.1 - 0.026 14.3 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 cIII protein family RRM_1 PF00076.22 GAX27224.1 - 1.8e-38 130.2 0.0 3e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 GAX27224.1 - 5.1e-05 23.2 0.0 0.065 13.2 0.0 2.2 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_7 PF16367.5 GAX27224.1 - 0.0097 16.0 0.0 6.2 7.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif GDP_Man_Dehyd PF16363.5 GAX27225.1 - 2.4e-63 214.5 0.0 5.9e-63 213.3 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX27225.1 - 4.9e-57 193.2 0.0 6.9e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX27225.1 - 8.1e-20 71.0 0.0 1.1e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAX27225.1 - 2.9e-18 66.0 0.0 3.5e-17 62.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX27225.1 - 5.7e-14 51.9 0.0 8.2e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX27225.1 - 3.3e-12 46.1 0.0 5.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 GAX27225.1 - 1.4e-05 25.1 0.0 7.1e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 GAX27225.1 - 5.6e-05 22.7 0.1 0.0021 17.5 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GAX27225.1 - 0.00022 21.2 0.0 0.00093 19.1 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox PF00070.27 GAX27225.1 - 0.0063 17.0 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 GAX27225.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 GAX27225.1 - 0.012 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAX27225.1 - 0.028 14.7 0.1 0.092 13.0 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 GAX27225.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 GAX27225.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase pPIWI_RE_REase PF18154.1 GAX27226.1 - 0.041 13.8 0.2 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 REase associating with pPIWI_RE EamA PF00892.20 GAX27227.1 - 1.9e-06 28.1 28.0 0.00035 20.7 14.1 2.7 2 2 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAX27227.1 - 0.00012 21.6 7.8 0.00044 19.7 7.2 1.9 1 1 1 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 GAX27227.1 - 0.00022 20.5 5.0 0.00071 18.8 4.8 1.9 2 1 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.11 GAX27227.1 - 0.0025 17.0 5.8 0.0025 17.0 5.8 1.9 2 1 1 3 3 3 1 UAA transporter family PPR_2 PF13041.6 GAX27228.1 - 6.7e-49 163.9 6.7 5.8e-14 52.0 0.0 10.4 7 4 5 12 12 12 8 PPR repeat family PPR_1 PF12854.7 GAX27228.1 - 2.5e-37 126.3 6.9 1.4e-05 24.7 0.0 10.5 12 0 0 12 12 12 6 PPR repeat PPR PF01535.20 GAX27228.1 - 2e-36 121.7 10.7 2.5e-05 24.2 0.0 11.4 10 1 0 10 10 10 7 PPR repeat PPR_3 PF13812.6 GAX27228.1 - 2.7e-30 104.2 1.4 1e-05 25.5 0.0 8.8 5 3 4 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX27228.1 - 1.5e-12 47.3 0.9 7.6e-05 22.2 0.1 5.2 1 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 GAX27228.1 - 5.8e-05 22.9 0.0 5.2 7.0 0.0 5.6 4 1 4 8 8 8 1 Mitochondrial ATPase expression MRP-S27 PF10037.9 GAX27228.1 - 9.1e-05 21.5 0.0 0.33 9.8 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 GAX27228.1 - 0.00079 19.9 8.7 1.3 9.5 0.2 5.0 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX27228.1 - 0.016 16.0 3.4 80 4.5 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 GAX27228.1 - 0.08 12.6 0.0 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 Rab-GTPase-TBC domain HEAT_2 PF13646.6 GAX27228.1 - 0.083 13.3 0.2 2.4 8.6 0.3 3.1 1 1 1 2 2 2 0 HEAT repeats T2SS_PulS_OutS PF09691.10 GAX27228.1 - 0.17 12.1 0.4 35 4.6 0.1 3.2 3 0 0 3 3 3 0 Type II secretion system pilotin lipoprotein (PulS_OutS) PsaL PF02605.15 GAX27228.1 - 0.21 11.3 0.2 19 4.9 0.1 2.6 1 1 1 2 2 2 0 Photosystem I reaction centre subunit XI CENP-T_C PF15511.6 GAX27229.1 - 9.6e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX27229.1 - 0.00017 21.9 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 GAX27229.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 GAX27229.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX27229.1 - 0.0047 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GAX27229.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAX27229.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 GAX27229.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 GAX27230.1 - 6.9e-54 181.7 1.0 7.7e-54 181.6 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GAX27230.1 - 0.00011 22.7 1.1 0.00014 22.5 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GAX27230.1 - 0.00072 19.6 0.3 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX27230.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAX27230.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAX27230.1 - 0.045 13.8 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 GAX27231.1 - 3e-19 69.7 0.4 4e-19 69.3 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX27231.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAX27231.1 - 0.0039 17.6 0.0 0.0068 16.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 GAX27231.1 - 0.0069 16.4 0.1 0.0078 16.3 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein Bt_P21 PF05560.11 GAX27231.1 - 0.045 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein CENP-T_C PF15511.6 GAX27233.1 - 9.6e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX27233.1 - 0.00017 21.9 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 GAX27233.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 GAX27233.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX27233.1 - 0.0047 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GAX27233.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAX27233.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 GAX27233.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) SET PF00856.28 GAX27234.1 - 4.9e-14 53.1 0.1 2.5e-07 31.2 0.0 3.8 2 2 1 3 3 3 2 SET domain SAF PF08666.12 GAX27234.1 - 0.11 13.1 0.0 11 6.7 0.0 3.3 3 0 0 3 3 3 0 SAF domain TLC PF03219.14 GAX27235.1 - 2e-137 458.9 16.9 2.6e-137 458.5 16.9 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF4492 PF14899.6 GAX27235.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) OST3_OST6 PF04756.13 GAX27235.1 - 0.94 8.8 11.0 0.64 9.3 1.0 2.9 3 1 1 4 4 4 0 OST3 / OST6 family, transporter family CBM9_1 PF06452.11 GAX27236.1 - 6e-06 26.3 0.2 1.1e-05 25.4 0.2 1.4 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like DUF285 PF03382.14 GAX27237.1 - 3.9e-56 188.0 26.6 1e-29 102.8 7.4 2.2 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 ATG11 PF10377.9 GAX27237.1 - 0.011 15.8 1.1 1.3 9.0 0.1 2.6 1 1 1 2 2 2 0 Autophagy-related protein 11 FXa_inhibition PF14670.6 GAX27237.1 - 0.052 13.8 1.5 0.12 12.7 1.5 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site HSV_VP16_C PF12149.8 GAX27237.1 - 2.5 8.2 4.5 0.98 9.5 0.7 2.1 2 0 0 2 2 2 0 Herpes simplex virus virion protein 16 C terminal ProRS-C_1 PF09180.11 GAX27238.1 - 5.8e-22 77.7 0.2 1.3e-21 76.6 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 GAX27238.1 - 8e-20 71.6 0.0 2.1e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAX27238.1 - 9.9e-19 67.3 0.0 2.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.15 GAX27238.1 - 1.9e-17 63.5 0.4 2.3e-16 60.0 0.2 2.5 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain baeRF_family11 PF18855.1 GAX27238.1 - 0.013 15.8 0.1 0.062 13.6 0.1 2.1 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 11 GST_C_3 PF14497.6 GAX27238.1 - 0.031 14.5 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain baeRF_family12 PF18856.1 GAX27238.1 - 0.08 13.5 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Ribosomal_S21e PF01249.18 GAX27239.1 - 7.9e-35 118.8 0.1 9.4e-35 118.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e PilA4 PF18682.1 GAX27240.1 - 0.17 12.3 0.1 1.7 9.1 0.1 2.1 2 0 0 2 2 2 0 Pilin A4 DnaJ PF00226.31 GAX27241.1 - 3.9e-18 65.3 1.9 3.9e-18 65.3 1.9 1.9 2 0 0 2 2 2 1 DnaJ domain DUF3858 PF12970.7 GAX27241.1 - 0.0084 16.1 1.4 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Domain of Unknown Function with PDB structure (DUF3858) Conotoxin PF02950.17 GAX27241.1 - 0.029 15.4 2.1 0.13 13.3 0.0 3.0 3 0 0 3 3 3 0 Conotoxin Sec62 PF03839.16 GAX27241.1 - 0.06 12.8 0.3 0.06 12.8 0.3 3.0 3 0 0 3 3 3 0 Translocation protein Sec62 DUF4200 PF13863.6 GAX27242.1 - 0.019 15.4 1.5 0.029 14.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) MYO10_CC PF16735.5 GAX27242.1 - 0.12 12.5 5.4 1.1 9.4 1.2 2.3 1 1 1 2 2 2 0 Unconventional myosin-X coiled coil domain Trimer_CC PF08954.11 GAX27242.1 - 0.12 11.9 2.4 0.31 10.6 2.4 1.8 1 1 0 1 1 1 0 Trimerisation motif Peptidase_M6 PF05547.11 GAX27244.1 - 4.2e-08 32.0 3.6 7.9e-07 27.8 3.6 2.5 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 Peptidase_M6 PF05547.11 GAX27245.1 - 7.5e-11 41.1 7.1 7.5e-11 41.1 7.1 2.5 2 1 0 2 2 2 1 Immune inhibitor A peptidase M6 Asp_protease PF09668.10 GAX27246.1 - 8.5e-42 141.9 0.5 1.5e-41 141.0 0.5 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GAX27246.1 - 2.5e-14 53.6 0.0 4.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAX27246.1 - 5.4e-08 33.4 0.0 9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GAX27246.1 - 0.0073 16.6 0.0 0.018 15.3 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Complex1_LYR_2 PF13233.6 GAX27246.1 - 5.2 7.9 9.8 19 6.1 0.1 2.5 1 1 0 2 2 2 0 Complex1_LYR-like SUI1 PF01253.22 GAX27247.1 - 1.5e-14 54.2 1.5 2.4e-14 53.6 1.5 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cwf_Cwc_15 PF04889.12 GAX27247.1 - 0.015 15.0 1.7 0.02 14.6 1.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 GAX27247.1 - 0.031 14.6 5.5 0.059 13.7 5.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ebola_NP PF05505.12 GAX27247.1 - 0.037 12.3 0.7 0.045 12.1 0.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4611 PF15387.6 GAX27247.1 - 0.055 13.7 4.9 0.082 13.1 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) GCIP PF13324.6 GAX27247.1 - 0.055 13.1 0.6 0.073 12.7 0.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF1726 PF08351.11 GAX27247.1 - 0.074 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DNA_pol_phi PF04931.13 GAX27247.1 - 0.15 10.1 1.2 0.18 9.9 1.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GAX27247.1 - 0.23 9.7 1.5 0.27 9.5 1.5 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 GAX27247.1 - 0.3 9.4 2.8 0.36 9.1 2.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus YL1 PF05764.13 GAX27247.1 - 0.31 11.1 8.6 0.34 11.0 8.2 1.3 1 1 0 1 1 1 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 GAX27247.1 - 6.6 7.2 10.7 13 6.3 10.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MatE PF01554.18 GAX27248.1 - 5.6e-19 68.4 34.7 2.7e-14 53.1 10.4 2.7 3 0 0 3 3 3 2 MatE MurJ PF03023.14 GAX27248.1 - 3.3e-13 49.1 8.8 3.3e-13 49.1 8.8 2.4 2 1 1 3 3 3 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 GAX27248.1 - 1.1e-10 41.7 6.5 1.1e-10 41.7 6.5 3.7 2 2 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Fer4_13 PF13370.6 GAX27249.1 - 9.5e-16 58.1 3.0 3.5e-15 56.3 3.0 2.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 GAX27249.1 - 1.3e-06 29.1 2.5 1.3e-06 29.1 2.5 2.8 3 1 0 3 3 3 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 GAX27249.1 - 0.0018 18.4 1.6 0.0018 18.4 1.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Pox_Rap94 PF03294.14 GAX27249.1 - 0.069 11.3 0.0 0.094 10.8 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 Fer4_NifH PF00142.18 GAX27249.1 - 0.13 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Fer4_10 PF13237.6 GAX27249.1 - 1.7 8.8 11.3 1.9 8.7 2.6 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain CS PF04969.16 GAX27250.1 - 1.8e-10 41.7 0.0 3.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 CS domain TPT PF03151.16 GAX27251.1 - 5.7e-28 98.1 3.8 1.4e-27 96.8 3.8 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX27251.1 - 2.9e-10 40.4 25.7 7.9e-07 29.3 8.9 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAX27251.1 - 0.023 13.9 9.0 0.15 11.2 9.0 2.1 1 1 0 1 1 1 0 UAA transporter family Spectrin PF00435.21 GAX27252.1 - 0.00021 21.7 4.9 0.00028 21.3 4.9 1.2 1 0 0 1 1 1 1 Spectrin repeat Nsp1_C PF05064.13 GAX27252.1 - 0.015 15.1 1.6 0.022 14.6 1.6 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region Phage_GP20 PF06810.11 GAX27252.1 - 0.019 14.8 10.1 0.023 14.5 10.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 HrpB2 PF09487.10 GAX27252.1 - 0.025 15.0 0.6 0.028 14.8 0.6 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) OmpH PF03938.14 GAX27252.1 - 0.094 13.0 9.7 0.12 12.7 9.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UPRTase PF14681.6 GAX27253.1 - 4e-61 206.1 0.2 4.7e-61 205.8 0.2 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAX27253.1 - 0.011 15.3 0.1 0.026 14.0 0.1 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase domain Thioredoxin PF00085.20 GAX27254.1 - 3e-11 43.2 0.0 4.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX27254.1 - 0.00028 21.1 0.0 0.00059 20.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 GAX27254.1 - 0.044 13.1 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family KAAG1 PF15354.6 GAX27254.1 - 0.054 14.0 0.4 3.4 8.3 0.0 2.3 1 1 1 2 2 2 0 Kidney-associated antigen 1 DIM1 PF02966.16 GAX27254.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 GAX27254.1 - 0.13 12.5 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like TENA_THI-4 PF03070.16 GAX27255.1 - 4.3e-10 39.8 0.2 5.3e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Flu_NS2 PF00601.19 GAX27256.1 - 0.027 14.8 1.2 0.06 13.6 1.2 1.6 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) NUC PF18510.1 GAX27256.1 - 0.034 14.6 0.9 0.065 13.7 0.9 1.5 1 1 0 1 1 1 0 Nuclease domain FAM76 PF16046.5 GAX27256.1 - 0.41 10.0 5.9 0.55 9.5 5.9 1.1 1 0 0 1 1 1 0 FAM76 protein Aa_trans PF01490.18 GAX27257.1 - 6.8e-53 179.8 16.4 6.8e-53 179.8 16.4 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein FAM70 PF14967.6 GAX27257.1 - 0.028 13.9 0.4 0.053 13.0 0.4 1.4 1 0 0 1 1 1 0 FAM70 protein Trp_Tyr_perm PF03222.13 GAX27257.1 - 0.32 10.0 17.1 0.017 14.2 11.5 1.7 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family TrmB PF01978.19 GAX27258.1 - 0.065 13.1 0.1 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB ABC_tran PF00005.27 GAX27259.1 - 5.3e-27 95.0 3.9 1.6e-14 54.6 0.1 4.5 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAX27259.1 - 2.5e-13 50.5 0.0 2.5e-06 27.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX27259.1 - 6.8e-09 36.3 2.0 1.5e-05 25.5 0.7 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAX27259.1 - 1.8e-06 28.3 2.2 0.0021 18.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 GAX27259.1 - 4.9e-06 26.1 2.2 0.53 9.7 0.0 3.5 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX27259.1 - 1.1e-05 25.1 0.5 0.16 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_27 PF13514.6 GAX27259.1 - 5.8e-05 22.8 0.1 0.39 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAX27259.1 - 9e-05 22.7 0.7 0.28 11.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAX27259.1 - 0.00051 20.0 0.4 0.63 9.9 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_13 PF13166.6 GAX27259.1 - 0.0006 18.6 0.1 0.01 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 GAX27259.1 - 0.00089 19.4 0.4 0.64 10.3 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 GAX27259.1 - 0.0011 19.1 0.2 1.2 9.2 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 GAX27259.1 - 0.0011 19.5 0.0 0.079 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX27259.1 - 0.0056 16.3 0.8 0.88 9.1 0.6 3.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX27259.1 - 0.0077 15.5 0.1 0.2 10.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.19 GAX27259.1 - 0.014 15.0 0.4 0.66 9.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 GAX27259.1 - 0.016 15.7 0.0 9.2 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GAX27259.1 - 0.018 14.2 0.1 5.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 GAX27259.1 - 0.033 14.4 0.4 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 GAX27259.1 - 0.04 13.4 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 NACHT PF05729.12 GAX27259.1 - 0.041 13.8 6.6 0.55 10.1 1.6 3.3 2 2 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 GAX27259.1 - 0.049 13.3 0.1 7.3 6.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAX27259.1 - 0.057 13.4 0.5 14 5.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 GAX27259.1 - 0.058 13.1 0.1 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arf PF00025.21 GAX27259.1 - 0.088 12.3 0.2 1.5 8.3 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA PF00004.29 GAX27259.1 - 0.11 12.9 0.1 5.7 7.4 0.0 2.8 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAX27259.1 - 0.13 12.7 0.0 23 5.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Flavin_Reduct PF01613.18 GAX27260.1 - 8.1e-11 42.2 0.0 2.7e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Flavin reductase like domain Patched PF02460.18 GAX27262.1 - 1.8e-35 122.3 33.4 1.4e-18 66.4 6.4 3.2 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 GAX27262.1 - 1e-20 74.1 7.0 1e-20 74.1 7.0 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Acetyltransf_1 PF00583.25 GAX27263.1 - 3.8e-13 49.7 0.1 5.3e-13 49.2 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX27263.1 - 2.3e-09 37.6 0.0 3.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX27263.1 - 1.2e-07 31.7 0.1 3.2e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAX27263.1 - 0.0014 18.8 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAX27263.1 - 0.0024 18.5 0.0 0.0048 17.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX27263.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein CBS PF00571.28 GAX27263.1 - 0.027 14.9 0.1 0.05 14.1 0.1 1.5 1 0 0 1 1 1 0 CBS domain PanZ PF12568.8 GAX27263.1 - 0.047 13.4 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 GAX27263.1 - 0.089 12.9 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF11 PF01345.18 GAX27264.1 - 0.093 13.0 0.2 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF11 Pkinase PF00069.25 GAX27265.1 - 2.3e-06 27.2 0.0 3.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX27265.1 - 3.1e-05 22.9 0.0 3.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase GHMP_kinases_C PF08544.13 GAX27265.1 - 0.12 12.8 0.1 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal SAYSvFN PF10260.9 GAX27268.1 - 3.9e-12 45.9 0.0 9.5e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) DUF2721 PF11026.8 GAX27269.1 - 0.00075 19.4 0.1 0.00075 19.4 0.1 3.4 2 1 2 4 4 4 1 Protein of unknown function (DUF2721) DUF4386 PF14329.6 GAX27269.1 - 0.0013 18.6 0.2 0.0013 18.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4386) DUF4131 PF13567.6 GAX27269.1 - 0.0023 17.6 0.4 0.0023 17.6 0.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4131) DUF2142 PF09913.9 GAX27269.1 - 0.0068 15.3 1.5 0.014 14.3 1.5 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) DUF4079 PF13301.6 GAX27269.1 - 0.0081 16.3 2.3 0.012 15.8 1.5 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF4079) TauE PF01925.19 GAX27269.1 - 0.0084 15.8 3.7 0.0084 15.8 3.7 1.8 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE DUF3290 PF11694.8 GAX27269.1 - 0.021 14.8 0.3 0.021 14.8 0.3 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3290) UbiA PF01040.18 GAX27269.1 - 0.022 14.1 0.2 0.022 14.1 0.2 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family DivIC PF04977.15 GAX27269.1 - 0.043 13.6 9.4 0.043 13.6 4.2 2.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 GAX27269.1 - 0.057 13.5 3.0 0.16 12.1 3.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor RasGAP_C PF03836.15 GAX27269.1 - 0.064 13.4 0.9 0.12 12.5 0.9 1.4 1 0 0 1 1 1 0 RasGAP C-terminus YibE_F PF07907.11 GAX27269.1 - 0.16 11.4 5.9 0.091 12.2 0.7 2.5 3 0 0 3 3 3 0 YibE/F-like protein Ax_dynein_light PF10211.9 GAX27269.1 - 0.17 11.8 8.2 0.079 12.9 3.5 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain YfhO PF09586.10 GAX27269.1 - 0.24 9.6 2.6 0.22 9.7 1.5 1.4 1 1 0 1 1 1 0 Bacterial membrane protein YfhO MARVEL PF01284.23 GAX27269.1 - 0.29 11.2 6.9 0.9 9.6 1.1 2.6 2 1 0 2 2 2 0 Membrane-associating domain DivIVA PF05103.13 GAX27269.1 - 0.34 11.0 6.9 0.1 12.7 3.2 1.9 2 0 0 2 2 2 0 DivIVA protein AI-2E_transport PF01594.16 GAX27269.1 - 0.37 9.9 9.7 0.02 14.0 2.5 2.0 1 1 1 2 2 2 0 AI-2E family transporter SirB PF04247.12 GAX27269.1 - 0.63 10.1 9.4 0.063 13.4 3.3 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF5408 PF17402.2 GAX27269.1 - 0.72 9.8 3.0 2.2 8.2 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5408) ZapB PF06005.12 GAX27269.1 - 3.4 8.2 13.1 0.32 11.5 5.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB DUF5313 PF17240.2 GAX27269.1 - 8 6.9 7.2 2.8 8.4 1.3 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5313) DUF2236 PF09995.9 GAX27270.1 - 3.2e-24 86.4 0.4 5.2e-24 85.7 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) ABC1 PF03109.16 GAX27272.1 - 1e-23 83.7 0.0 2.5e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX27272.1 - 1.7e-05 24.9 0.2 0.0011 18.9 0.0 3.0 1 1 2 3 3 3 1 Phosphotransferase enzyme family CTNNB1_binding PF08347.11 GAX27273.1 - 0.027 14.7 0.3 0.027 14.7 0.3 1.8 2 0 0 2 2 2 0 N-terminal CTNNB1 binding SPT6_acidic PF14632.6 GAX27273.1 - 0.81 10.3 8.1 0.87 10.2 0.2 2.7 3 0 0 3 3 3 0 Acidic N-terminal SPT6 SnoaL_2 PF12680.7 GAX27274.1 - 3e-05 24.6 0.0 6.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 GAX27274.1 - 0.14 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase PIG-S PF10510.9 GAX27275.1 - 3.7e-05 22.8 0.7 0.00013 21.0 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein H2O2_YaaD PF03883.14 GAX27276.1 - 9.1e-65 218.4 0.2 1.1e-64 218.2 0.2 1.1 1 0 0 1 1 1 1 Peroxide stress protein YaaA Thg1 PF04446.12 GAX27276.1 - 0.046 13.8 2.4 1.4 8.9 0.2 2.8 2 1 1 3 3 3 0 tRNAHis guanylyltransferase DUF413 PF04219.12 GAX27277.1 - 0.061 13.3 1.7 0.099 12.7 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF TruD PF01142.18 GAX27278.1 - 4.8e-63 213.4 0.0 2.8e-62 210.9 0.0 2.1 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) RPOL_N PF14700.6 GAX27278.1 - 0.16 11.4 0.4 1.6 8.0 0.0 2.3 3 0 0 3 3 3 0 DNA-directed RNA polymerase N-terminal Arf PF00025.21 GAX27279.1 - 2e-66 222.8 0.1 2.2e-66 222.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAX27279.1 - 8.5e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAX27279.1 - 2.9e-12 46.5 0.0 3.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAX27279.1 - 8.3e-12 44.9 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAX27279.1 - 3.7e-10 39.5 0.9 2.7e-05 23.5 0.0 2.4 2 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 GAX27279.1 - 7e-09 35.8 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX27279.1 - 1e-05 25.0 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX27279.1 - 0.002 17.7 0.0 0.099 12.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAX27279.1 - 0.041 12.9 0.0 0.28 10.1 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 GAX27279.1 - 0.052 13.1 0.0 3.2 7.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 GAX27279.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea F-box PF00646.33 GAX27280.1 - 0.00035 20.4 0.3 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAX27280.1 - 0.00039 20.3 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 F-box-like RVT_2 PF07727.14 GAX27282.1 - 4.4e-40 137.9 0.0 7.5e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX27282.1 - 3.5e-06 27.2 0.0 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 GAX27282.1 - 0.0046 16.8 0.1 0.015 15.2 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain NCA2 PF08637.10 GAX27283.1 - 2.6e-17 62.9 1.9 5.7e-17 61.8 0.1 2.2 2 1 0 2 2 2 1 ATP synthase regulation protein NCA2 Aldose_epim PF01263.20 GAX27284.1 - 4.9e-30 104.9 0.1 7.1e-30 104.3 0.1 1.2 1 1 0 1 1 1 1 Aldose 1-epimerase PUB PF09409.10 GAX27285.1 - 3.1e-18 65.5 0.0 5.5e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 GAX27285.1 - 1.3e-07 31.7 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Frtz PF11768.8 GAX27285.1 - 0.054 11.8 0.0 0.1 10.9 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DEAD PF00270.29 GAX27286.1 - 5.9e-21 75.0 0.0 1.5e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 GAX27286.1 - 6.5e-15 55.0 0.1 1.1e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 GAX27286.1 - 1.4e-10 41.5 0.0 1e-09 38.7 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX27286.1 - 4.7e-07 30.0 0.0 1.5e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 GAX27286.1 - 0.0081 16.0 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 Helicase T2SSE PF00437.20 GAX27286.1 - 0.042 12.9 0.0 0.095 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HHH_5 PF14520.6 GAX27286.1 - 0.075 13.7 0.0 0.22 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Pkinase PF00069.25 GAX27287.1 - 1.6e-11 44.1 0.0 1.1e-10 41.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GAX27287.1 - 6.9e-11 42.5 3.0 1.2e-05 26.0 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat HEAT PF02985.22 GAX27287.1 - 3e-05 23.9 14.6 0.36 11.2 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 GAX27287.1 - 7.6e-05 23.0 0.1 0.011 16.2 0.2 3.6 3 0 0 3 3 3 1 HEAT repeats Kinase-like PF14531.6 GAX27287.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 GAX27287.1 - 0.0014 17.9 0.0 0.0054 16.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase UME PF08064.13 GAX27287.1 - 0.046 13.6 0.2 0.84 9.6 0.0 2.9 3 0 0 3 3 3 0 UME (NUC010) domain HEAT_EZ PF13513.6 GAX27287.1 - 0.13 12.8 0.8 54 4.4 0.4 4.4 4 1 1 5 5 5 0 HEAT-like repeat IGPS PF00218.21 GAX27288.1 - 1.7e-24 86.4 0.0 2.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 GAX27288.1 - 0.00046 19.7 1.1 0.032 13.7 0.0 3.0 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.17 GAX27288.1 - 0.0045 16.1 0.3 0.018 14.1 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 GAX27288.1 - 0.054 12.5 3.4 2.6 7.0 0.1 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain TUDOR_5 PF18359.1 GAX27289.1 - 4.4e-05 23.1 11.0 0.014 15.1 0.0 3.2 4 0 0 4 4 4 2 Histone methyltransferase Tudor domain 1 53-BP1_Tudor PF09038.10 GAX27289.1 - 0.033 14.2 4.5 9 6.3 0.3 3.5 2 1 1 3 3 3 0 Tumour suppressor p53-binding protein-1 Tudor LBR_tudor PF09465.10 GAX27289.1 - 0.093 12.5 15.2 0.16 11.8 0.7 3.5 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain TOBE_2 PF08402.10 GAX27289.1 - 0.29 11.3 2.0 8 6.7 0.0 3.4 4 0 0 4 4 4 0 TOBE domain Nucleoporin_C PF03177.14 GAX27291.1 - 0.0047 15.7 0.4 0.078 11.7 1.0 2.1 1 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal GT-D PF08759.11 GAX27291.1 - 0.026 14.2 0.0 0.071 12.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase GT-D fold p450 PF00067.22 GAX27294.1 - 1.9e-44 152.2 0.1 7.8e-38 130.4 0.0 2.6 1 1 1 2 2 2 2 Cytochrome P450 ETC_C1_NDUFA5 PF04716.14 GAX27295.1 - 0.00053 19.7 0.0 0.00081 19.1 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region SwrA PF17423.2 GAX27297.1 - 0.025 14.6 1.3 1.3 9.1 0.0 3.0 3 0 0 3 3 3 0 Swarming motility protein FAM163 PF15069.6 GAX27298.1 - 0.3 11.5 5.7 0.066 13.7 1.3 2.1 2 1 0 2 2 2 0 FAM163 family FAD_binding_3 PF01494.19 GAX27300.1 - 6.1e-08 32.3 0.4 0.00049 19.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 GAX27300.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 GAX27300.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 GAX27300.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DIX PF00778.17 GAX27301.1 - 8.9e-10 38.3 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 DIX domain TTL PF03133.15 GAX27302.1 - 3.2e-19 69.2 0.0 4.9e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAX27302.1 - 1.3e-05 24.6 0.0 3.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GAX27302.1 - 0.00011 21.6 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp 3H PF02829.14 GAX27302.1 - 0.056 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 3H domain Rdx PF10262.9 GAX27304.1 - 7.8e-47 157.4 0.0 2.9e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 Rdx family zf-TFIIB PF13453.6 GAX27304.1 - 0.008 15.5 0.3 3.5 7.0 0.1 3.0 3 0 0 3 3 3 2 Transcription factor zinc-finger Cyclin_N PF00134.23 GAX27305.1 - 2e-12 47.0 2.2 4.6e-12 45.8 0.1 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX27305.1 - 4.3e-05 23.6 0.2 0.0001 22.3 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain ECH_1 PF00378.20 GAX27306.1 - 7.6e-51 172.8 0.1 9.4e-51 172.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX27306.1 - 8.6e-31 107.6 0.3 4.1e-27 95.6 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HGTP_anticodon PF03129.20 GAX27307.1 - 3.5e-20 72.0 0.0 9.7e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 GAX27307.1 - 5.1e-06 26.6 3.0 1.2e-05 25.4 3.0 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 GAX27307.1 - 5.5e-06 26.5 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Cep57_CLD_2 PF14197.6 GAX27307.1 - 0.0054 16.8 4.9 0.012 15.6 4.9 1.6 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.22 GAX27307.1 - 0.019 15.2 4.7 0.045 14.0 4.7 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 GAX27307.1 - 0.13 12.9 2.4 0.15 12.7 1.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA LidA_Long_CC PF18641.1 GAX27307.1 - 0.19 11.8 3.8 0.35 10.9 3.8 1.4 1 0 0 1 1 1 0 LidA long coiled-coil domain Aminotran_3 PF00202.21 GAX27308.1 - 1.3e-16 60.3 0.0 2.6e-14 52.7 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 GAX27308.1 - 3.1e-14 53.3 0.2 5.3e-13 49.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX27308.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF775 PF05603.12 GAX27309.1 - 8.4e-31 107.1 0.2 1.6e-29 102.8 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DUF2795 PF11387.8 GAX27310.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) Pkinase PF00069.25 GAX27311.1 - 3.6e-48 164.2 0.0 7.2e-48 163.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX27311.1 - 2.8e-10 39.9 0.0 2.1e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX27311.1 - 9.6e-05 21.3 0.2 0.00042 19.2 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 GAX27311.1 - 0.0039 17.2 1.2 0.0039 17.2 1.2 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX27311.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 GAX27314.1 - 1.5e-05 24.7 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX27314.1 - 0.019 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC48_2 PF02933.17 GAX27314.1 - 0.023 14.5 2.0 0.16 11.7 0.4 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 DUF2852 PF11014.8 GAX27314.1 - 2.7 8.1 7.6 0.76 9.9 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Ribosomal_L29 PF00831.23 GAX27315.1 - 2.3e-16 59.5 1.0 2.3e-16 59.5 1.0 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 GAX27315.1 - 0.019 15.4 1.2 0.019 15.4 1.2 1.9 2 0 0 2 2 2 0 Snapin/Pallidin 5-FTHF_cyc-lig PF01812.20 GAX27315.1 - 0.81 9.5 6.9 5.6 6.8 0.3 2.0 1 1 1 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family TBD PF12845.7 GAX27315.1 - 1.3 9.0 4.5 2.9 7.8 0.1 2.9 3 0 0 3 3 3 0 TBD domain AAA PF00004.29 GAX27316.1 - 6.6e-42 143.1 0.0 1.5e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAX27316.1 - 5.1e-11 42.3 0.1 2.2e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAX27316.1 - 1.9e-09 37.2 0.2 4.1e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX27316.1 - 2.2e-07 31.4 0.4 0.00012 22.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAX27316.1 - 8.2e-07 29.1 0.1 7.3e-06 26.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX27316.1 - 3.8e-05 23.9 0.0 9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAX27316.1 - 4.5e-05 23.3 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX27316.1 - 0.00014 22.2 0.7 0.0093 16.2 0.0 2.7 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.13 GAX27316.1 - 0.0012 18.0 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAX27316.1 - 0.0018 18.6 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 GAX27316.1 - 0.0026 17.2 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAX27316.1 - 0.0027 17.5 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAX27316.1 - 0.0028 18.2 1.4 0.0054 17.3 0.0 2.3 3 1 0 3 3 1 1 AAA domain TIP49 PF06068.13 GAX27316.1 - 0.0034 16.6 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 GAX27316.1 - 0.0042 16.7 0.5 0.013 15.2 0.1 2.0 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 GAX27316.1 - 0.0047 17.1 0.1 0.017 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAX27316.1 - 0.0052 17.0 0.4 0.012 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 GAX27316.1 - 0.0069 15.9 0.0 0.016 14.8 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 GAX27316.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1043 PF06295.12 GAX27316.1 - 0.016 15.2 0.5 0.032 14.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) AAA_11 PF13086.6 GAX27316.1 - 0.017 14.9 1.5 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAX27316.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAX27316.1 - 0.024 14.3 0.0 0.07 12.8 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 GAX27316.1 - 0.024 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAX27316.1 - 0.027 14.0 0.1 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX27316.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GAX27316.1 - 0.033 13.3 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GrpE PF01025.19 GAX27316.1 - 0.033 13.8 0.2 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 GrpE ATPase PF06745.13 GAX27316.1 - 0.037 13.4 0.1 0.16 11.3 0.0 2.1 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 GAX27316.1 - 0.053 13.4 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.16 GAX27316.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 GAX27316.1 - 0.074 13.6 0.5 0.29 11.6 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 GAX27316.1 - 0.084 12.6 1.0 0.11 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain CLZ PF16526.5 GAX27316.1 - 0.36 11.2 6.0 0.13 12.6 2.2 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5082 PF16888.5 GAX27316.1 - 0.69 10.2 3.5 2.1 8.7 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) AAA_23 PF13476.6 GAX27316.1 - 0.99 9.9 3.2 45 4.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain FSH1 PF03959.13 GAX27318.1 - 1.1e-42 146.1 0.0 1.3e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 GAX27318.1 - 0.0004 20.3 0.0 0.00084 19.2 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAX27318.1 - 0.0028 17.0 0.2 0.53 9.5 0.1 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAX27318.1 - 0.0045 16.9 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 GAX27318.1 - 0.0055 17.3 0.0 0.0079 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX27318.1 - 0.0062 16.2 0.2 4.5 6.8 0.0 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold DUF3530 PF12048.8 GAX27318.1 - 0.0065 15.9 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_3 PF07859.13 GAX27318.1 - 0.0076 16.1 0.0 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 GAX27318.1 - 0.091 12.3 0.0 0.79 9.2 0.0 2.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Palm_thioest PF02089.15 GAX27318.1 - 0.17 11.7 0.1 0.31 10.8 0.1 1.7 2 1 0 2 2 2 0 Palmitoyl protein thioesterase Mpv17_PMP22 PF04117.12 GAX27319.1 - 1.1e-12 48.0 2.0 1.1e-12 48.0 2.0 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF647 PF04884.14 GAX27320.1 - 3.4e-77 259.4 0.3 4.8e-77 258.8 0.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis NAD_binding_5 PF07994.12 GAX27321.1 - 5.4e-142 472.9 0.2 6.4e-142 472.7 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAX27321.1 - 5.4e-47 158.6 2.0 6.3e-47 158.3 0.8 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Med2 PF11214.8 GAX27321.1 - 0.01 16.0 0.1 0.027 14.6 0.1 1.8 1 0 0 1 1 1 0 Mediator complex subunit 2 TMF_TATA_bd PF12325.8 GAX27321.1 - 0.027 14.7 0.7 0.093 13.0 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Glyco_hydro_3 PF00933.21 GAX27322.1 - 2.9e-58 197.7 0.0 3.8e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAX27322.1 - 2.1e-30 106.2 0.0 3.2e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAX27322.1 - 3.5e-08 33.4 0.0 7.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain VirJ PF06057.11 GAX27322.1 - 0.049 13.5 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) TPR_2 PF07719.17 GAX27323.1 - 0.00021 21.1 0.1 0.44 10.8 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX27323.1 - 0.00074 20.1 0.3 0.0027 18.3 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX27323.1 - 0.0011 18.2 0.3 0.061 12.5 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX27323.1 - 0.0038 17.7 2.8 0.0073 16.8 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX27323.1 - 0.0067 16.2 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX27323.1 - 0.011 15.8 0.4 6.1 7.1 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX27323.1 - 0.012 16.3 7.5 0.023 15.5 0.3 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX27323.1 - 0.026 14.8 0.7 9.5 6.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 GAX27323.1 - 0.044 12.8 0.1 0.05 12.6 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.9 GAX27323.1 - 0.068 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 SHNi-TPR TPR_10 PF13374.6 GAX27323.1 - 0.079 12.9 0.4 1.4 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat VWA_2 PF13519.6 GAX27323.1 - 0.11 13.1 0.5 2.7 8.7 0.1 2.3 1 1 2 3 3 3 0 von Willebrand factor type A domain Bestrophin PF01062.21 GAX27324.1 - 9e-31 107.3 0.1 1.5e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PsbY PF06298.11 GAX27324.1 - 0.64 10.0 7.5 0.51 10.3 1.3 2.5 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) polyprenyl_synt PF00348.17 GAX27325.1 - 3.2e-55 187.0 0.1 3.7e-55 186.8 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase FA_desaturase PF00487.24 GAX27326.1 - 5.3e-31 108.4 16.9 9.6e-31 107.5 16.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAX27326.1 - 2.5e-18 66.0 0.1 5.2e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain INCA1 PF15142.6 GAX27326.1 - 0.029 14.4 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 INCA1 Myb_DNA-binding PF00249.31 GAX27327.1 - 1.6e-42 143.5 12.8 1.1e-15 57.5 0.6 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX27327.1 - 1.6e-30 105.1 5.4 3.6e-16 59.1 0.1 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX27327.1 - 9.3e-07 28.7 1.9 0.032 14.1 0.0 3.0 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 GAX27327.1 - 0.0073 16.3 0.1 2.2 8.4 0.1 3.2 2 1 1 3 3 3 1 SLIDE ATP19 PF11022.8 GAX27327.1 - 0.12 12.7 1.1 0.54 10.7 0.0 2.6 2 0 0 2 2 2 0 ATP synthase subunit K SANT_DAMP1_like PF16282.5 GAX27327.1 - 1.4 9.2 3.8 22 5.3 0.5 3.2 1 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 FAD_binding_3 PF01494.19 GAX27329.1 - 2.3e-13 50.1 0.0 1.3e-11 44.4 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAX27329.1 - 2.1e-07 31.1 0.1 6.3e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX27329.1 - 2.9e-05 23.5 0.0 0.0024 17.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Ank_5 PF13857.6 GAX27329.1 - 3.8e-05 23.9 0.0 9.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DAO PF01266.24 GAX27329.1 - 0.00025 20.7 0.1 0.014 15.0 0.0 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX27329.1 - 0.001 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAX27329.1 - 0.0019 18.7 0.0 0.16 12.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 GAX27329.1 - 0.015 15.9 0.0 0.04 14.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX27329.1 - 0.018 15.6 0.0 0.21 12.3 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Chor_lyase PF04345.13 GAX27329.1 - 0.024 14.3 0.2 5.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Chorismate lyase Ank PF00023.30 GAX27329.1 - 0.029 14.8 0.0 0.094 13.2 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat HI0933_like PF03486.14 GAX27329.1 - 0.055 12.2 0.0 0.15 10.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 GAX27329.1 - 0.12 11.6 0.0 1.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Ank_4 PF13637.6 GAX27329.1 - 0.14 12.7 0.0 0.38 11.4 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SKN1 PF03935.15 GAX27330.1 - 9.8e-63 212.3 8.2 8.2e-52 176.2 4.2 3.8 3 1 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) PhyH PF05721.13 GAX27331.1 - 1.3e-10 41.9 0.0 1.9e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) EcoEI_R_C PF08463.10 GAX27332.1 - 0.11 12.6 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 EcoEI R protein C-terminal Hydrolase_6 PF13344.6 GAX27333.1 - 9.2e-19 67.4 0.0 2.4e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX27333.1 - 5.1e-14 52.1 0.1 3.2e-13 49.5 0.0 2.3 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX27333.1 - 0.00013 22.4 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX27333.1 - 0.011 15.9 0.2 0.38 10.8 0.1 2.4 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Peptidase_M28 PF04389.17 GAX27333.1 - 0.13 11.9 0.2 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 Peptidase family M28 UBA_5 PF16577.5 GAX27333.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 UBA domain S1 PF00575.23 GAX27334.1 - 0.019 15.3 4.8 2.6 8.4 0.0 3.8 4 0 0 4 4 4 0 S1 RNA binding domain RNase_II_C_S1 PF18614.1 GAX27334.1 - 0.067 13.2 0.1 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain CrgA PF06781.12 GAX27335.1 - 0.1 12.7 1.5 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 Cell division protein CrgA HMG_box PF00505.19 GAX27336.1 - 8.4e-11 42.1 3.5 6.2e-05 23.3 0.8 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27336.1 - 5.7e-08 33.2 6.7 2.1e-07 31.4 3.7 2.9 1 1 0 1 1 1 1 HMG-box domain ZnuA PF01297.17 GAX27336.1 - 0.097 12.1 0.7 0.16 11.4 0.7 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic CTP_transf_like PF01467.26 GAX27337.1 - 1.4e-05 25.3 0.0 3.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 GAX27337.1 - 0.0022 17.9 0.1 0.0039 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD synthetase eIF2A PF08662.11 GAX27338.1 - 3e-47 161.0 0.0 6.5e-46 156.7 0.0 2.8 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SET PF00856.28 GAX27339.1 - 4.7e-12 46.6 0.0 7.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 SET domain Castor1_N PF18700.1 GAX27339.1 - 0.16 11.8 0.5 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain DEAD PF00270.29 GAX27340.1 - 3e-42 144.4 0.1 5.4e-42 143.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX27340.1 - 3.8e-26 91.6 0.1 1.9e-25 89.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX27340.1 - 2.1e-05 24.6 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1853 PF08907.11 GAX27340.1 - 0.0067 16.2 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1853) ERCC3_RAD25_C PF16203.5 GAX27340.1 - 0.031 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HSF_DNA-bind PF00447.17 GAX27341.1 - 9.4e-22 77.4 0.1 1.5e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Glyco_hydro_16 PF00722.21 GAX27342.1 - 8.1e-07 28.7 0.0 2e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 EF-hand_7 PF13499.6 GAX27346.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair TraB PF01963.17 GAX27347.1 - 1.1e-20 74.6 0.0 1.6e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 TraB family DUF2384 PF09722.10 GAX27347.1 - 0.12 12.4 1.2 1.7 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) TFIIA PF03153.13 GAX27348.1 - 0.0023 18.0 8.0 0.0023 18.0 8.0 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NPIP PF06409.11 GAX27348.1 - 0.018 14.1 2.9 0.027 13.5 2.9 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) RdRP_3 PF00998.23 GAX27349.1 - 0.023 13.4 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase TAFII28 PF04719.14 GAX27350.1 - 1.3e-06 28.4 0.0 3.5e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 hTAFII28-like protein conserved region RPN2_C PF18004.1 GAX27350.1 - 7.1 6.5 14.5 0.35 10.8 3.5 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPP1-like PF11833.8 GAX27351.1 - 2.5e-13 50.1 1.3 8.4e-13 48.4 1.3 1.8 1 1 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like WD40 PF00400.32 GAX27352.1 - 2.6e-28 97.7 15.0 8.8e-09 35.9 0.1 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX27352.1 - 1.3e-08 35.0 0.0 0.026 14.8 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX27352.1 - 0.00055 19.0 0.0 0.24 10.3 0.0 3.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GAX27352.1 - 0.1 11.3 0.0 0.81 8.4 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like C2 PF00168.30 GAX27353.1 - 9.6e-14 51.5 0.0 3e-12 46.7 0.0 2.5 1 1 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 GAX27353.1 - 0.00027 21.5 0.5 0.2 12.3 0.0 3.9 4 0 0 4 4 4 1 Putative heavy-metal-binding zf-C2H2_2 PF12756.7 GAX27354.1 - 5.9e-26 90.7 1.1 5.9e-26 90.7 1.1 2.4 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAX27354.1 - 0.012 16.3 3.3 0.12 13.2 2.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAX27354.1 - 0.059 13.9 6.8 0.35 11.4 3.8 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type CENP-B_dimeris PF09026.10 GAX27354.1 - 0.068 13.6 7.1 0.14 12.6 7.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-met PF12874.7 GAX27354.1 - 1.6 9.2 10.0 0.7 10.4 2.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAX27354.1 - 3.7 8.0 16.9 1.1 9.6 2.8 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_2 PF13639.6 GAX27355.1 - 1e-07 32.2 11.9 1e-07 32.2 11.9 2.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX27355.1 - 4.9e-07 29.5 12.4 1.1e-06 28.4 12.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX27355.1 - 5.9e-07 29.7 9.4 5.9e-07 29.7 9.4 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX27355.1 - 4e-06 26.6 9.9 7.3e-06 25.8 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX27355.1 - 0.00013 21.8 6.2 0.00029 20.6 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX27355.1 - 0.00034 20.3 6.1 0.00079 19.1 6.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAX27355.1 - 0.0031 17.1 6.6 0.0057 16.3 6.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAX27355.1 - 0.005 16.9 5.0 0.019 15.0 4.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX27355.1 - 0.026 14.6 8.4 0.1 12.6 8.6 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAX27355.1 - 0.072 13.1 8.1 0.14 12.1 8.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 GAX27355.1 - 0.11 12.5 8.6 0.22 11.5 8.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 GAX27355.1 - 0.15 12.1 4.0 0.43 10.6 4.0 1.8 1 0 0 1 1 1 0 Zinc-finger ADK_lid PF05191.14 GAX27355.1 - 0.52 10.3 4.5 11 6.1 1.5 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid FANCL_C PF11793.8 GAX27355.1 - 4.5 7.5 11.4 7.1 6.9 8.0 2.8 3 1 0 3 3 3 0 FANCL C-terminal domain CUE PF02845.16 GAX27356.1 - 2.8e-05 23.7 0.0 0.00018 21.1 0.0 2.3 2 0 0 2 2 2 1 CUE domain Peptidase_S10 PF00450.22 GAX27357.1 - 5.5e-84 283.0 0.0 6.4e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Chloroa_b-bind PF00504.21 GAX27358.1 - 1.1e-29 104.0 0.0 1.4e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX27359.1 - 1.3e-34 120.1 0.0 1.6e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pro_isomerase PF00160.21 GAX27360.1 - 0.0022 18.3 0.0 0.21 11.8 0.0 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mod_r PF07200.13 GAX27360.1 - 0.014 15.5 7.9 0.014 15.5 7.9 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prp19 PF08606.11 GAX27360.1 - 0.021 14.8 1.7 0.021 14.8 1.7 2.2 2 0 0 2 2 2 0 Prp19/Pso4-like Spc7 PF08317.11 GAX27360.1 - 0.035 13.0 11.4 0.054 12.4 11.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Zein-binding PF04576.15 GAX27360.1 - 0.038 14.3 8.3 0.078 13.3 6.5 2.3 1 1 0 1 1 1 0 Zein-binding DUF4407 PF14362.6 GAX27360.1 - 0.065 12.6 8.1 0.099 12.0 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 GAX27360.1 - 0.11 12.6 16.2 0.24 11.5 16.2 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 GAX27360.1 - 0.12 11.0 3.8 0.19 10.3 3.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A SKA2 PF16740.5 GAX27360.1 - 0.14 11.9 11.5 0.14 12.0 9.8 1.9 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Phage_int_SAM_2 PF12834.7 GAX27360.1 - 0.15 12.8 2.6 0.14 12.9 0.9 1.8 2 0 0 2 2 1 0 Phage integrase, N-terminal MctB PF11382.8 GAX27360.1 - 0.15 11.7 7.8 0.23 11.1 7.8 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Rootletin PF15035.6 GAX27360.1 - 0.22 11.5 16.2 0.5 10.4 16.2 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GP46 PF07409.12 GAX27360.1 - 0.31 10.8 4.0 0.26 11.0 1.9 2.0 1 1 1 2 2 2 0 Phage protein GP46 COG2 PF06148.11 GAX27360.1 - 0.38 10.8 13.8 0.5 10.4 4.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HTH_11 PF08279.12 GAX27360.1 - 0.81 9.7 4.4 22 5.1 0.2 3.4 3 0 0 3 3 3 0 HTH domain IFT57 PF10498.9 GAX27360.1 - 0.86 8.5 12.4 1.3 7.9 12.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1759 PF03564.15 GAX27360.1 - 1.2 9.1 4.0 4.9 7.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) TMF_DNA_bd PF12329.8 GAX27360.1 - 1.3 9.1 13.1 8.6 6.4 0.2 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 GAX27360.1 - 2.1 6.9 10.0 2.9 6.4 8.2 1.7 1 1 1 2 2 2 0 AAA domain HisKA_3 PF07730.13 GAX27360.1 - 2.6 8.7 12.9 0.39 11.3 3.8 3.2 2 1 1 3 3 3 0 Histidine kinase TMPIT PF07851.13 GAX27360.1 - 2.9 7.0 7.4 4.7 6.4 7.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran_CTD PF16326.5 GAX27360.1 - 3.2 8.1 8.8 5.3 7.4 1.9 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF1664 PF07889.12 GAX27360.1 - 6.2 6.9 11.1 3.4 7.7 6.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 GAX27360.1 - 8.3 5.9 13.4 12 5.4 13.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit F-box PF00646.33 GAX27361.1 - 0.00011 22.0 0.2 0.00039 20.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAX27361.1 - 0.018 14.9 0.1 0.076 12.9 0.0 2.2 2 0 0 2 2 2 0 F-box-like Rep_fac-A_C PF08646.10 GAX27362.1 - 3e-33 114.6 0.0 7.8e-33 113.3 0.0 1.7 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GAX27362.1 - 3.3e-28 97.5 1.0 4.2e-26 90.7 0.0 3.5 4 0 0 4 4 4 1 Replication protein A OB domain Rep-A_N PF04057.12 GAX27362.1 - 6.5e-22 77.5 1.3 1.2e-21 76.7 1.3 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 GAX27362.1 - 2.1e-14 53.3 0.3 1.3e-08 34.7 0.0 4.5 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain POT1 PF02765.17 GAX27362.1 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 CDC24_OB3 PF17244.2 GAX27362.1 - 0.019 14.7 0.1 7.7 6.1 0.0 2.6 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 zf-RRN7 PF11781.8 GAX27362.1 - 0.079 12.7 1.3 0.15 11.8 1.3 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 2OG-FeII_Oxy_3 PF13640.6 GAX27364.1 - 2.1e-11 44.5 0.0 3.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HMG_box PF00505.19 GAX27365.1 - 2.2e-12 47.2 8.3 7.8e-08 32.6 6.6 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27365.1 - 4.4e-11 43.2 3.7 8e-08 32.8 2.7 2.5 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.13 GAX27365.1 - 0.067 13.8 0.1 0.067 13.8 0.1 2.8 2 1 0 2 2 2 0 YABBY protein OCC1 PF15506.6 GAX27365.1 - 4.2 7.6 5.5 0.39 10.9 0.6 1.8 2 0 0 2 2 2 0 OCC1 family Peptidase_M16_M PF16187.5 GAX27367.1 - 1.1e-51 175.8 0.0 3.9e-29 101.8 0.0 2.3 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAX27367.1 - 7.6e-31 107.1 0.0 1.5e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAX27367.1 - 4e-22 79.1 0.0 2.4e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain zf-RING_2 PF13639.6 GAX27368.1 - 5.3e-08 33.1 6.0 1.2e-07 31.9 6.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX27368.1 - 3.2e-05 23.6 4.0 7.8e-05 22.3 4.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAX27368.1 - 0.00012 22.0 3.5 0.00025 21.0 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX27368.1 - 0.00023 21.0 6.8 0.0004 20.2 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX27368.1 - 0.0009 19.5 2.7 0.0019 18.4 2.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain CUE PF02845.16 GAX27368.1 - 0.0029 17.3 0.0 0.0089 15.7 0.0 1.9 1 0 0 1 1 1 1 CUE domain zf-C3HC4_3 PF13920.6 GAX27368.1 - 0.0041 16.9 5.6 0.0079 16.0 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX27368.1 - 0.0066 16.3 6.6 0.014 15.2 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.11 GAX27368.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 GAGA factor zf-RING_5 PF14634.6 GAX27368.1 - 0.15 12.0 5.8 0.44 10.5 5.9 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX27368.1 - 0.17 12.0 3.2 0.55 10.3 3.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 GAX27368.1 - 0.29 11.3 1.4 0.61 10.2 1.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger PHD PF00628.29 GAX27368.1 - 1.1 9.3 4.1 2 8.4 4.1 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 GAX27368.1 - 6.1 6.8 7.4 12 5.9 7.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FA_desaturase PF00487.24 GAX27369.1 - 0.041 13.7 0.9 0.043 13.6 0.9 1.0 1 0 0 1 1 1 0 Fatty acid desaturase STT3 PF02516.14 GAX27370.1 - 2.2e-42 145.6 20.7 1.1e-29 103.8 6.9 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 GAX27371.1 - 0.0018 17.3 0.1 0.0026 16.7 0.1 1.3 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Peptidase_M13_N PF05649.13 GAX27372.1 - 6e-89 299.4 0.1 7.6e-89 299.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAX27372.1 - 1.8e-67 226.9 0.0 1.6e-66 223.8 0.0 2.5 3 0 0 3 3 3 1 Peptidase family M13 PSK_trans_fac PF07704.11 GAX27372.1 - 0.16 12.8 0.1 0.16 12.8 0.1 2.5 3 0 0 3 3 3 0 Rv0623-like transcription factor WASH-7_C PF14746.6 GAX27372.1 - 0.33 10.6 2.6 0.22 11.2 0.5 1.8 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Vps54 PF07928.12 GAX27373.1 - 1.4e-36 125.9 0.6 3.8e-36 124.5 0.6 1.8 1 0 0 1 1 1 1 Vps54-like protein LEA_3 PF03242.13 GAX27374.1 - 0.061 14.1 0.6 0.14 12.9 0.6 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein BSP PF04450.12 GAX27374.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase of plants and bacteria PWI PF01480.17 GAX27374.1 - 0.095 13.0 1.0 0.34 11.3 0.3 2.2 2 0 0 2 2 2 0 PWI domain ACP_syn_III_C PF08541.10 GAX27375.1 - 7.8e-40 134.9 0.1 9.6e-39 131.5 0.1 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 GAX27375.1 - 6.9e-26 89.9 1.4 6.6e-25 86.8 0.3 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 GAX27375.1 - 4.6e-06 26.2 0.1 0.00016 21.1 0.0 2.3 2 1 1 3 3 3 1 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.15 GAX27375.1 - 0.00014 21.9 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Thiolase_C PF02803.18 GAX27375.1 - 0.0016 18.1 0.6 0.017 14.7 0.3 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain Chal_sti_synt_N PF00195.19 GAX27375.1 - 0.085 12.3 0.1 0.25 10.7 0.1 1.7 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain ADH_N PF08240.12 GAX27376.1 - 7.1e-20 70.9 3.0 1.7e-19 69.7 3.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAX27376.1 - 1.3e-08 34.9 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAX27376.1 - 3.6e-05 23.3 0.0 7e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAX27376.1 - 0.0088 17.1 0.0 0.49 11.5 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX27376.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ketoacyl-synt PF00109.26 GAX27377.1 - 2.1e-38 132.3 2.3 2.4e-38 132.2 1.6 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAX27377.1 - 4e-31 107.5 0.1 6.5e-30 103.6 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAX27377.1 - 0.0078 15.6 0.3 0.047 13.1 0.2 2.3 2 1 1 3 3 3 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 GAX27377.1 - 0.026 15.0 0.0 0.088 13.3 0.0 1.9 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension CYSTM PF12734.7 GAX27378.1 - 0.00039 20.7 3.5 0.0011 19.2 2.5 2.4 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance WBP-1 PF11669.8 GAX27378.1 - 0.0033 18.0 0.6 0.26 12.0 0.0 2.3 2 0 0 2 2 2 2 WW domain-binding protein 1 WBP-1 PF11669.8 GAX27379.1 - 0.00079 20.0 0.0 0.023 15.3 0.0 2.3 2 0 0 2 2 2 1 WW domain-binding protein 1 Mucin PF01456.17 GAX27379.1 - 0.0027 17.7 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Mito_carr PF00153.27 GAX27380.1 - 1.4e-35 121.1 2.1 2.2e-12 46.7 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.6 GAX27381.1 - 1.2e-18 67.1 0.1 1.2e-05 25.4 0.0 5.7 5 1 0 5 5 5 3 PPR repeat family PPR_1 PF12854.7 GAX27381.1 - 5.9e-17 61.1 5.5 2.2e-07 30.4 0.0 6.9 8 0 0 8 8 8 3 PPR repeat PPR PF01535.20 GAX27381.1 - 4.2e-16 58.0 11.2 1.7e-06 27.9 0.0 8.5 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 GAX27381.1 - 1.2e-14 54.1 0.2 0.00072 19.6 0.0 5.6 4 2 2 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX27381.1 - 7.7e-05 22.2 1.1 0.031 13.7 0.0 3.3 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP FA_desaturase PF00487.24 GAX27382.1 - 1.1e-33 117.2 3.4 1.1e-33 117.2 3.4 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAX27382.1 - 4.4e-09 36.3 0.0 9.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SNase PF00565.17 GAX27383.1 - 6.5e-35 119.9 0.0 2.5e-08 34.3 0.0 6.9 5 2 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 GAX27383.1 - 8.7e-12 45.1 0.0 2.7e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Tudor domain Agenet PF05641.12 GAX27383.1 - 0.02 15.3 0.0 0.88 10.1 0.0 2.7 2 0 0 2 2 2 0 Agenet domain TPR_8 PF13181.6 GAX27384.1 - 0.00041 20.4 7.5 0.084 13.1 0.6 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Emaravirus_P4 PF16505.5 GAX27384.1 - 0.02 14.0 1.5 0.036 13.1 1.5 1.3 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily FlhC PF05280.11 GAX27384.1 - 0.024 14.3 0.3 0.11 12.1 0.2 1.9 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) TPR_1 PF00515.28 GAX27384.1 - 4 7.4 9.9 1 9.3 0.9 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAX27384.1 - 6 7.3 14.4 1.5 9.2 1.3 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat EF-hand_8 PF13833.6 GAX27386.1 - 0.056 13.3 0.1 11 6.0 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair B5 PF03484.15 GAX27386.1 - 0.14 12.5 0.0 73 3.8 0.0 3.9 4 0 0 4 4 4 0 tRNA synthetase B5 domain Pkinase_Tyr PF07714.17 GAX27387.1 - 1e-36 126.6 0.0 1.5e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX27387.1 - 5.1e-30 104.7 0.0 8.9e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX27387.1 - 2.7e-06 26.4 0.1 6.5e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAX27387.1 - 0.015 14.8 0.1 0.5 9.9 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL LNP1 PF15419.6 GAX27387.1 - 0.016 15.5 2.4 0.036 14.3 2.4 1.5 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 APH PF01636.23 GAX27387.1 - 0.016 15.1 0.2 0.07 13.0 0.0 2.0 2 1 0 3 3 3 0 Phosphotransferase enzyme family PIP49_C PF12260.8 GAX27387.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF563 PF04577.14 GAX27388.1 - 1.1e-06 29.0 0.4 2.3e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Piezo_RRas_bdg PF12166.8 GAX27388.1 - 0.08 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain DUF475 PF04332.15 GAX27389.1 - 0.075 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF475) Ribosomal_60s PF00428.19 GAX27390.1 - 3.9e-16 59.4 3.0 4.9e-16 59.1 3.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein NCA2 PF08637.10 GAX27391.1 - 6.4e-17 61.7 0.1 6.4e-17 61.7 0.1 2.3 2 1 0 2 2 2 1 ATP synthase regulation protein NCA2 Aldose_epim PF01263.20 GAX27392.1 - 1.4e-30 106.6 0.0 2.2e-30 106.0 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase GAPES2 PF17156.4 GAX27392.1 - 0.036 13.8 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain PUB PF09409.10 GAX27393.1 - 1.9e-19 69.4 0.0 3.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 GAX27393.1 - 1.5e-08 34.7 0.0 2.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain Frtz PF11768.8 GAX27393.1 - 0.0031 15.9 0.0 0.0058 15.0 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz DEAD PF00270.29 GAX27394.1 - 4.9e-22 78.5 0.0 1.3e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 GAX27394.1 - 2.1e-15 56.6 0.1 3.6e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 GAX27394.1 - 1.4e-10 41.4 0.0 6.9e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX27394.1 - 6.1e-08 32.8 0.0 1.8e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 GAX27394.1 - 0.0055 16.6 0.0 0.023 14.5 0.0 2.1 1 0 0 1 1 1 1 Helicase T2SSE PF00437.20 GAX27394.1 - 0.068 12.2 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Pkinase PF00069.25 GAX27395.1 - 5.3e-14 52.2 0.0 7e-13 48.5 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 GAX27395.1 - 3.7e-10 40.2 2.2 4.6e-05 24.1 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Kinase-like PF14531.6 GAX27395.1 - 1.4e-05 24.6 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 GAX27395.1 - 2.7e-05 23.6 0.0 8.4e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase UME PF08064.13 GAX27395.1 - 0.063 13.2 0.1 1.8 8.6 0.0 2.9 3 0 0 3 3 3 0 UME (NUC010) domain HEAT PF02985.22 GAX27395.1 - 0.071 13.4 6.9 0.31 11.4 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 GAX27395.1 - 0.076 13.4 0.1 13 6.3 0.2 3.6 3 0 0 3 3 3 0 HEAT repeats IGPS PF00218.21 GAX27396.1 - 2.5e-24 85.8 0.0 3.3e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 GAX27396.1 - 0.00035 20.1 1.3 0.02 14.4 0.0 3.0 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.17 GAX27396.1 - 0.0085 15.2 0.3 0.043 12.9 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 GAX27396.1 - 0.055 12.5 3.3 3 6.7 0.2 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain TUDOR_5 PF18359.1 GAX27397.1 - 6.7e-10 38.5 3.9 0.0045 16.6 0.0 3.9 4 0 0 4 4 4 3 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 GAX27397.1 - 3.5e-08 33.2 4.4 0.0072 16.1 0.0 3.7 3 0 0 3 3 3 3 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 GAX27397.1 - 0.022 14.5 15.1 0.22 11.4 0.5 4.3 4 0 0 4 4 4 0 Lamin-B receptor of TUDOR domain 53-BP1_Tudor PF09038.10 GAX27397.1 - 0.063 13.2 5.0 7 6.6 0.3 3.6 2 1 1 3 3 3 0 Tumour suppressor p53-binding protein-1 Tudor DUF5047 PF16466.5 GAX27397.1 - 0.076 13.4 0.0 14 6.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5047) FXR_C1 PF16096.5 GAX27397.1 - 0.47 10.7 5.4 2.3 8.5 0.4 2.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 GT-D PF08759.11 GAX27400.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Ribosomal_L35p PF01632.19 GAX27402.1 - 0.51 10.9 2.1 0.86 10.2 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L35 p450 PF00067.22 GAX27404.1 - 9.3e-45 153.2 0.0 9.8e-38 130.1 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 ETC_C1_NDUFA5 PF04716.14 GAX27405.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region FAD_binding_3 PF01494.19 GAX27409.1 - 2.2e-07 30.5 0.5 0.00072 18.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 GAX27409.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 GAX27409.1 - 0.059 12.6 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 GAX27409.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DIX PF00778.17 GAX27410.1 - 8.2e-10 38.4 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 DIX domain TTL PF03133.15 GAX27411.1 - 1.8e-18 66.7 0.0 3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAX27411.1 - 0.00021 20.6 0.0 0.00049 19.4 0.0 1.7 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GAX27411.1 - 0.0018 17.6 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp R2K_2 PF18299.1 GAX27411.1 - 0.079 12.8 0.0 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 ANAPC3 PF12895.7 GAX27411.1 - 0.14 12.4 1.6 0.57 10.4 1.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Rdx PF10262.9 GAX27413.1 - 6.8e-49 164.0 0.0 1.6e-23 82.7 0.0 2.1 2 0 0 2 2 2 2 Rdx family zf-TFIIB PF13453.6 GAX27413.1 - 0.086 12.2 0.6 11 5.4 0.2 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger Cyclin_N PF00134.23 GAX27414.1 - 1.3e-12 47.6 1.1 1.2e-11 44.4 0.0 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX27414.1 - 4.5e-05 23.5 0.2 0.00011 22.3 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain ECH_1 PF00378.20 GAX27415.1 - 2.9e-50 170.9 0.1 3.6e-50 170.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX27415.1 - 2.3e-31 109.5 0.3 1e-27 97.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PMSR PF01625.21 GAX27416.1 - 5.6e-24 85.1 0.1 8.3e-24 84.5 0.1 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HGTP_anticodon PF03129.20 GAX27417.1 - 1.1e-20 73.6 0.0 2.9e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 GAX27417.1 - 5.1e-06 26.6 3.4 1.1e-05 25.5 3.4 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 GAX27417.1 - 6.9e-06 26.2 0.0 1.8e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Cep57_CLD_2 PF14197.6 GAX27417.1 - 0.0065 16.5 4.7 0.015 15.4 4.7 1.6 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.22 GAX27417.1 - 0.011 16.0 4.3 0.025 14.8 4.3 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain LidA_Long_CC PF18641.1 GAX27417.1 - 0.02 15.0 3.7 0.035 14.2 3.7 1.4 1 0 0 1 1 1 0 LidA long coiled-coil domain YabA PF06156.13 GAX27417.1 - 0.12 13.1 2.1 0.15 12.7 0.8 1.9 2 0 0 2 2 2 0 Initiation control protein YabA Aminotran_3 PF00202.21 GAX27418.1 - 3e-17 62.4 0.0 8e-15 54.4 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 GAX27418.1 - 3.3e-15 56.5 0.2 5.6e-14 52.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain DUF775 PF05603.12 GAX27420.1 - 4.9e-31 107.8 0.4 1.1e-29 103.4 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DUF2795 PF11387.8 GAX27421.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) Pkinase PF00069.25 GAX27422.1 - 8.4e-46 156.5 0.0 1.7e-45 155.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX27422.1 - 4.1e-10 39.4 0.0 1.5e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX27422.1 - 0.00036 19.4 0.2 0.0021 16.9 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 GAX27422.1 - 0.0037 17.2 3.8 0.0039 17.2 1.2 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAX27422.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 GAX27425.1 - 2.9e-05 23.8 0.0 6.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rox3 PF08633.10 GAX27425.1 - 0.03 14.6 6.4 0.02 15.2 4.5 1.5 1 1 1 2 2 2 0 Rox3 mediator complex subunit DUF2852 PF11014.8 GAX27425.1 - 1.4 9.1 10.1 0.25 11.5 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Ribosomal_L29 PF00831.23 GAX27426.1 - 2.8e-16 59.2 1.6 2.8e-16 59.2 1.6 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 GAX27426.1 - 0.018 15.5 1.6 0.018 15.5 1.6 1.9 2 0 0 2 2 2 0 Snapin/Pallidin 5-FTHF_cyc-lig PF01812.20 GAX27426.1 - 0.8 9.5 6.9 5.6 6.8 0.3 2.0 1 1 1 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family TBD PF12845.7 GAX27426.1 - 1.3 9.0 4.5 2.9 7.8 0.1 2.9 3 0 0 3 3 3 0 TBD domain AAA PF00004.29 GAX27427.1 - 6.6e-42 143.1 0.0 1.5e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAX27427.1 - 5.1e-11 42.3 0.1 2.2e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAX27427.1 - 1.9e-09 37.2 0.2 4.1e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAX27427.1 - 2.2e-07 31.4 0.4 0.00012 22.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAX27427.1 - 8.1e-07 29.1 0.1 7.3e-06 26.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAX27427.1 - 3.7e-05 23.9 0.0 9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAX27427.1 - 4.5e-05 23.2 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX27427.1 - 0.00015 22.1 0.8 0.0093 16.2 0.0 2.6 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.13 GAX27427.1 - 0.0012 18.0 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAX27427.1 - 0.0018 18.6 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 GAX27427.1 - 0.0026 17.2 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAX27427.1 - 0.0026 18.3 1.3 0.0054 17.3 0.0 2.3 3 1 0 3 3 1 1 AAA domain IstB_IS21 PF01695.17 GAX27427.1 - 0.0027 17.5 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 GAX27427.1 - 0.0034 16.6 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 GAX27427.1 - 0.0042 16.7 0.5 0.013 15.2 0.1 2.0 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 GAX27427.1 - 0.0046 17.1 0.1 0.017 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAX27427.1 - 0.0061 16.8 0.6 0.012 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 GAX27427.1 - 0.0069 15.9 0.0 0.016 14.8 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 GAX27427.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1043 PF06295.12 GAX27427.1 - 0.014 15.4 0.4 0.027 14.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) AAA_11 PF13086.6 GAX27427.1 - 0.019 14.7 1.8 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAX27427.1 - 0.021 14.9 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAX27427.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAX27427.1 - 0.024 14.3 0.0 0.07 12.8 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 GAX27427.1 - 0.027 14.0 0.1 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX27427.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GAX27427.1 - 0.033 13.3 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GrpE PF01025.19 GAX27427.1 - 0.034 13.8 0.4 0.12 12.1 0.3 1.8 2 0 0 2 2 2 0 GrpE ATPase PF06745.13 GAX27427.1 - 0.037 13.4 0.1 0.16 11.3 0.0 2.1 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 GAX27427.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX27427.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.16 GAX27427.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 GAX27427.1 - 0.077 13.5 0.5 0.29 11.6 0.0 2.2 2 1 0 2 2 2 0 ABC transporter CLZ PF16526.5 GAX27427.1 - 0.36 11.2 6.0 0.13 12.6 2.2 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5082 PF16888.5 GAX27427.1 - 0.68 10.2 3.5 2.1 8.7 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) AAA_23 PF13476.6 GAX27427.1 - 0.99 9.9 3.4 45 4.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-AD PF07776.15 GAX27428.1 - 0.079 13.2 1.5 0.18 12.0 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) FSH1 PF03959.13 GAX27429.1 - 1.4e-42 145.7 0.0 1.8e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 GAX27429.1 - 0.0016 19.1 0.0 0.0022 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAX27429.1 - 0.0027 17.5 0.0 0.0046 16.8 0.0 1.6 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF3530 PF12048.8 GAX27429.1 - 0.0063 16.0 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_3 PF07859.13 GAX27429.1 - 0.0068 16.3 0.0 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2201_N PF13203.6 GAX27429.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Ser_hydrolase PF06821.13 GAX27429.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 GAX27429.1 - 0.017 14.8 0.1 2.4 7.7 0.0 2.9 2 1 1 3 3 3 0 alpha/beta hydrolase fold DLH PF01738.18 GAX27429.1 - 0.047 13.2 0.0 0.17 11.4 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Mpv17_PMP22 PF04117.12 GAX27430.1 - 5.4e-13 48.9 2.0 5.4e-13 48.9 2.0 2.1 3 0 0 3 3 3 1 Mpv17 / PMP22 family DUF647 PF04884.14 GAX27431.1 - 7.1e-79 264.8 0.3 1e-78 264.3 0.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis NAD_binding_5 PF07994.12 GAX27432.1 - 2.7e-142 473.9 0.3 3.2e-142 473.7 0.3 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAX27432.1 - 4.2e-47 158.9 1.6 6.3e-47 158.3 0.8 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Med2 PF11214.8 GAX27432.1 - 0.014 15.5 0.1 0.038 14.1 0.1 1.8 1 0 0 1 1 1 0 Mediator complex subunit 2 TMF_TATA_bd PF12325.8 GAX27432.1 - 0.019 15.2 0.3 0.087 13.1 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Glyco_hydro_3 PF00933.21 GAX27433.1 - 7.8e-58 196.3 0.0 1e-57 196.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAX27433.1 - 1.5e-29 103.4 0.0 2.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAX27433.1 - 4.3e-08 33.1 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain VirJ PF06057.11 GAX27433.1 - 0.043 13.7 0.2 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) TPR_12 PF13424.6 GAX27434.1 - 0.0003 21.0 2.3 0.018 15.3 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX27434.1 - 0.00047 20.7 0.6 0.0027 18.3 0.0 2.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX27434.1 - 0.00047 19.5 0.3 0.0026 17.0 0.3 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX27434.1 - 0.00083 19.4 0.1 0.078 13.2 0.0 3.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX27434.1 - 0.00087 19.9 5.2 0.36 11.8 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX27434.1 - 0.0056 16.7 2.9 0.017 15.2 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX27434.1 - 0.011 16.2 2.5 0.13 12.8 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX27434.1 - 0.016 15.4 0.7 3 8.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAX27434.1 - 0.017 14.8 0.5 5.8 6.7 0.1 3.1 3 0 0 3 3 3 0 TPR repeat TPR_10 PF13374.6 GAX27434.1 - 0.019 14.8 0.5 0.15 12.0 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX27434.1 - 0.044 13.8 1.0 1.4 9.1 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX27434.1 - 0.077 12.8 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX27434.1 - 0.15 12.8 4.8 2.4 9.0 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Bestrophin PF01062.21 GAX27435.1 - 7.1e-31 107.7 0.1 1.3e-30 106.9 0.1 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PsbY PF06298.11 GAX27435.1 - 0.28 11.1 5.7 0.52 10.3 1.3 2.5 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) polyprenyl_synt PF00348.17 GAX27436.1 - 6.1e-57 192.6 0.1 7.2e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase FA_desaturase PF00487.24 GAX27437.1 - 7.5e-31 107.9 17.0 1.3e-30 107.0 17.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAX27437.1 - 2.6e-18 65.9 0.1 5.2e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain INCA1 PF15142.6 GAX27437.1 - 0.03 14.3 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 INCA1 Myb_DNA-binding PF00249.31 GAX27438.1 - 1.4e-42 143.6 12.1 1.1e-15 57.5 0.6 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX27438.1 - 6.2e-30 103.2 5.2 4.4e-16 58.9 0.1 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX27438.1 - 1e-06 28.6 1.9 0.036 14.0 0.0 3.0 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 GAX27438.1 - 0.0032 17.5 0.1 0.87 9.6 0.0 3.2 2 1 0 2 2 2 1 SLIDE ATP19 PF11022.8 GAX27438.1 - 0.1 13.0 2.3 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 ATP synthase subunit K Myb_DNA-bind_2 PF08914.11 GAX27438.1 - 0.11 12.6 0.3 2.8 8.2 0.1 3.0 2 1 1 3 3 3 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 GAX27438.1 - 0.8 9.9 2.3 28 5.0 0.2 3.2 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 FAD_binding_3 PF01494.19 GAX27440.1 - 1.3e-12 47.6 0.0 1.4e-07 31.1 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAX27440.1 - 3.8e-07 30.2 0.1 1.2e-06 28.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAX27440.1 - 6.2e-05 22.4 0.1 0.0038 16.5 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX27440.1 - 7.6e-05 22.4 0.1 0.014 15.0 0.0 2.5 1 1 2 3 3 3 1 FAD dependent oxidoreductase Ank_5 PF13857.6 GAX27440.1 - 0.00043 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) FAD_binding_2 PF00890.24 GAX27440.1 - 0.0029 16.8 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Ank_2 PF12796.7 GAX27440.1 - 0.0039 17.7 0.0 0.0098 16.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Pyr_redox PF00070.27 GAX27440.1 - 0.0058 17.2 0.1 0.35 11.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ank PF00023.30 GAX27440.1 - 0.0089 16.4 0.0 0.032 14.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 GAX27440.1 - 0.022 15.3 0.0 0.33 11.6 0.0 2.9 3 0 0 3 3 2 0 Ankyrin repeat Amino_oxidase PF01593.24 GAX27440.1 - 0.047 13.0 0.0 0.47 9.7 0.0 2.3 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAX27440.1 - 0.059 12.1 0.1 0.22 10.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein SKN1 PF03935.15 GAX27441.1 - 9.7e-63 212.3 8.9 6.7e-52 176.5 4.1 3.7 3 1 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) PhyH PF05721.13 GAX27442.1 - 2.2e-12 47.7 0.1 6.4e-12 46.2 0.1 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF5554 PF17709.1 GAX27443.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5554) Hydrolase_6 PF13344.6 GAX27444.1 - 4.6e-19 68.4 0.0 1.2e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX27444.1 - 2.7e-14 53.0 0.1 1.4e-13 50.7 0.1 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAX27444.1 - 0.00037 20.9 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX27444.1 - 0.0081 16.3 0.2 0.21 11.7 0.1 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Peptidase_M28 PF04389.17 GAX27444.1 - 0.16 11.6 0.3 0.31 10.7 0.2 1.5 2 0 0 2 2 2 0 Peptidase family M28 S1 PF00575.23 GAX27445.1 - 0.0029 17.9 7.0 0.28 11.6 0.0 4.0 4 0 0 4 4 4 2 S1 RNA binding domain RNase_II_C_S1 PF18614.1 GAX27445.1 - 0.026 14.5 0.2 0.51 10.3 0.1 2.6 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain APT PF03440.14 GAX27445.1 - 0.17 11.9 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain CrgA PF06781.12 GAX27446.1 - 0.13 12.4 1.4 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 Cell division protein CrgA Ycf4 PF02392.16 GAX27446.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Ycf4 HMG_box PF00505.19 GAX27447.1 - 8.2e-11 42.2 4.0 4.5e-05 23.8 1.2 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27447.1 - 1.2e-06 28.9 6.2 6.9e-06 26.6 3.7 2.9 1 1 0 1 1 1 1 HMG-box domain ZnuA PF01297.17 GAX27447.1 - 0.027 13.9 0.5 0.041 13.3 0.5 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic CTP_transf_like PF01467.26 GAX27448.1 - 1.7e-06 28.3 0.0 1.8e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 GAX27448.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 FAD synthetase eIF2A PF08662.11 GAX27449.1 - 1.1e-47 162.4 0.0 2.6e-46 158.0 0.0 2.8 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SET PF00856.28 GAX27450.1 - 5.5e-12 46.4 0.0 8.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 SET domain DEAD PF00270.29 GAX27451.1 - 1.8e-42 145.1 0.0 3e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX27451.1 - 1.3e-26 93.1 0.0 8e-26 90.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX27451.1 - 6.7e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAX27451.1 - 0.048 12.9 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HSF_DNA-bind PF00447.17 GAX27452.1 - 1.8e-22 79.7 0.1 2.9e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Glyco_hydro_16 PF00722.21 GAX27453.1 - 9.1e-07 28.5 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 EBV-NA3 PF05009.12 GAX27454.1 - 2.5 7.6 4.8 3.3 7.2 4.8 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Herpes_UL17 PF04559.12 GAX27455.1 - 0.0038 16.1 0.1 0.0051 15.7 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL17 protein DUF4083 PF13314.6 GAX27456.1 - 4.6 7.2 4.8 2.2 8.3 0.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) EF-hand_7 PF13499.6 GAX27457.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX27457.1 - 0.0012 18.2 0.0 0.0069 15.9 0.0 2.1 2 0 0 2 2 2 1 EF hand TraC PF07820.12 GAX27457.1 - 0.071 13.4 0.2 0.11 12.8 0.2 1.3 1 0 0 1 1 1 0 TraC-like protein EF-hand_8 PF13833.6 GAX27457.1 - 0.087 12.7 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair TraB PF01963.17 GAX27458.1 - 3.4e-18 66.5 0.0 5.1e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 TraB family MatE PF01554.18 GAX27459.1 - 8.4e-27 93.8 27.5 1.3e-17 64.0 14.0 2.2 2 0 0 2 2 2 2 MatE DUF3506 PF12014.8 GAX27460.1 - 1.7e-14 54.0 1.1 1.7e-12 47.5 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) Rrp44_CSD1 PF17216.3 GAX27461.1 - 0.0089 15.7 1.6 0.018 14.8 1.6 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain DUF2839 PF10999.8 GAX27461.1 - 0.051 13.9 0.2 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) YEATS PF03366.16 GAX27462.1 - 2.9e-26 91.3 0.1 6.2e-26 90.2 0.0 1.6 2 0 0 2 2 2 1 YEATS family DUF4279 PF14106.6 GAX27462.1 - 0.13 12.5 0.1 13 6.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) O-FucT PF10250.9 GAX27463.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase PepSY PF03413.19 GAX27463.1 - 0.14 12.8 0.3 0.25 12.0 0.3 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Pro_isomerase PF00160.21 GAX27464.1 - 2.5e-27 96.1 0.0 4.1e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Acyl_transf_1 PF00698.21 GAX27467.1 - 2.9e-23 82.9 0.5 3.8e-23 82.5 0.5 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 GAX27467.1 - 0.0022 17.8 0.3 0.028 14.1 0.3 2.2 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis GBP PF02263.19 GAX27468.1 - 4.2e-48 163.9 1.4 8.1e-48 162.9 1.4 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain DUF4303 PF14136.6 GAX27468.1 - 0.058 13.1 1.8 0.12 12.1 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) AAA_16 PF13191.6 GAX27468.1 - 0.063 13.7 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ICMT PF04140.14 GAX27469.1 - 7.2e-22 77.6 2.7 9.7e-22 77.2 0.7 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAX27469.1 - 5.9e-09 36.3 0.8 5.9e-09 36.3 0.8 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase MotA_ExbB PF01618.16 GAX27469.1 - 0.06 13.1 0.1 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family LRR_6 PF13516.6 GAX27470.1 - 1.7e-24 83.7 36.1 0.00068 19.5 0.0 15.3 17 0 0 17 17 17 8 Leucine Rich repeat LRR_4 PF12799.7 GAX27470.1 - 8.7e-19 67.3 20.2 0.0083 16.5 1.2 11.1 6 3 6 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX27470.1 - 5.3e-17 61.3 20.5 3.5e-06 26.7 0.3 9.2 8 3 1 10 10 10 5 Leucine rich repeat LRR_9 PF14580.6 GAX27470.1 - 2.3e-05 24.0 0.2 0.37 10.3 0.1 4.1 1 1 2 4 4 4 2 Leucine-rich repeat DUF4890 PF16231.5 GAX27470.1 - 0.08 13.4 0.1 0.25 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) LRR_1 PF00560.33 GAX27470.1 - 0.22 12.2 35.6 25 6.0 0.4 11.2 11 3 1 12 12 12 0 Leucine Rich Repeat Guanylate_cyc PF00211.20 GAX27473.1 - 9e-23 80.8 0.6 6.1e-10 39.0 0.0 2.9 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 GAX27473.1 - 8.8e-08 32.7 0.0 2.5e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAX27473.1 - 0.0001 22.6 0.0 0.0008 19.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX27473.1 - 0.0099 16.2 0.0 2.2 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF4777 PF16007.5 GAX27473.1 - 0.024 14.9 0.1 0.078 13.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) TPR_MalT PF17874.1 GAX27473.1 - 0.024 14.0 0.1 1.7 7.9 0.1 3.2 2 1 2 4 4 4 0 MalT-like TPR region AAA_29 PF13555.6 GAX27473.1 - 0.038 13.7 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_10 PF13374.6 GAX27473.1 - 0.088 12.7 0.2 15 5.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX27473.1 - 0.13 12.4 0.7 49 4.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAX27473.1 - 0.16 12.3 0.1 24 5.3 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 GAX27474.1 - 2.1e-13 49.9 0.0 4.2e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 GAX27474.1 - 1.8e-11 44.5 0.0 1.2e-10 41.9 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GAX27475.1 - 1.3e-33 114.5 17.5 2.1e-10 41.0 0.5 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX27475.1 - 9.6e-12 45.0 0.4 9.4e-05 22.6 0.0 5.6 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 GAX27475.1 - 5.5e-06 26.6 1.2 0.0038 17.5 0.1 3.3 3 1 0 3 3 3 2 WD40 associated region in TFIID subunit, NTD2 domain eIF2A PF08662.11 GAX27475.1 - 0.0005 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 GAX27475.1 - 0.056 12.7 0.6 0.67 9.1 0.0 2.4 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 GAX27475.1 - 0.07 12.4 0.0 0.17 11.2 0.0 1.6 1 1 1 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 GAX27475.1 - 0.072 11.6 0.0 0.14 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain His_Phos_1 PF00300.22 GAX27476.1 - 2.2e-12 47.1 0.1 9e-12 45.1 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Vps26 PF03643.15 GAX27477.1 - 2.1e-83 279.5 0.1 3.6e-82 275.5 0.1 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAX27477.1 - 0.0086 16.1 0.0 9 6.3 0.0 3.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SSXT PF05030.12 GAX27478.1 - 7.9e-05 22.2 0.3 0.00024 20.7 0.3 1.8 1 0 0 1 1 1 1 SSXT protein (N-terminal region) HMG14_17 PF01101.18 GAX27478.1 - 0.11 13.4 1.4 0.35 11.9 1.4 1.8 1 0 0 1 1 1 0 HMG14 and HMG17 Coprogen_oxidas PF01218.18 GAX27479.1 - 1.6e-132 440.7 0.0 1.9e-132 440.5 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glyco_hydro81C PF17652.1 GAX27480.1 - 2.1e-63 214.7 0.0 6.9e-63 213.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAX27480.1 - 8.4e-24 84.3 2.3 1.4e-23 83.6 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain O-FucT PF10250.9 GAX27483.1 - 1.9e-08 34.4 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pyr_redox_3 PF13738.6 GAX27484.1 - 9.2e-10 38.2 0.0 1.5e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX27484.1 - 1.5e-06 28.3 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAX27484.1 - 5.7e-06 25.9 0.0 8.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAX27484.1 - 1.8e-05 24.1 0.0 0.00046 19.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX27484.1 - 0.00027 20.6 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX27484.1 - 0.0024 17.9 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GAX27484.1 - 0.0025 16.6 0.0 0.0061 15.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 GAX27484.1 - 0.003 18.1 0.4 0.01 16.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX27484.1 - 0.0032 16.8 0.3 0.0055 16.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAX27484.1 - 0.0083 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAX27484.1 - 0.019 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAX27484.1 - 0.063 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.21 GAX27484.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family Amino_oxidase PF01593.24 GAX27485.1 - 1.2e-17 64.3 0.0 8.5e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX27485.1 - 9.5e-13 48.2 0.0 1.9e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAX27485.1 - 1.2e-05 25.3 0.3 0.16 12.0 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 GAX27485.1 - 6e-05 22.8 0.2 0.00011 21.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAX27485.1 - 0.00014 21.2 1.1 0.00072 18.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAX27485.1 - 0.00025 20.4 0.0 0.0016 17.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX27485.1 - 0.00095 18.0 0.6 0.0019 17.0 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 GAX27485.1 - 0.01 16.4 0.1 0.028 15.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAX27485.1 - 0.026 13.6 0.2 0.039 13.0 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 GAX27485.1 - 0.027 13.7 0.3 0.044 13.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 GAX27485.1 - 0.032 13.5 0.0 0.064 12.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 GAX27485.1 - 0.037 13.1 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAX27485.1 - 0.083 12.2 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase MCRA PF06100.11 GAX27485.1 - 0.12 11.1 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 MCRA family Rotamase PF00639.21 GAX27486.1 - 3.1e-21 76.1 0.0 3.5e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX27486.1 - 1.1e-17 64.6 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAX27486.1 - 2e-06 28.6 0.0 2.4e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 GAX27486.1 - 0.06 14.0 0.0 0.082 13.6 0.0 1.2 1 0 0 1 1 1 0 X8 domain Topoisom_bac PF01131.20 GAX27487.1 - 4.3e-105 352.1 0.0 5.4e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 GAX27487.1 - 3.7e-12 46.4 0.0 8.2e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain HypA PF01155.19 GAX27487.1 - 0.033 14.2 0.6 0.033 14.2 0.6 3.1 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FPG_IleRS PF06827.14 GAX27487.1 - 0.35 10.8 4.0 5.9 6.9 0.3 3.8 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Elf1 PF05129.13 GAX27487.1 - 2.6 8.2 22.2 1.2 9.2 0.4 4.5 2 1 3 5 5 5 0 Transcription elongation factor Elf1 like Ilar_coat PF01787.16 GAX27489.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein WD40 PF00400.32 GAX27490.1 - 1.3e-16 60.7 10.3 2.1e-07 31.5 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX27490.1 - 1.3e-05 25.4 0.3 0.013 15.8 0.1 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 GAX27490.1 - 0.0092 15.4 0.0 0.39 10.1 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5046) BBS2_Mid PF14783.6 GAX27490.1 - 0.018 15.1 0.0 9.9 6.3 0.0 3.8 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DAGK_cat PF00781.24 GAX27491.1 - 0.029 14.0 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF521 PF04412.13 GAX27492.1 - 2.7e-110 368.8 0.0 3.5e-110 368.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 GAX27492.1 - 1.2e-29 101.8 0.0 2.3e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase X swivel domain Rhodanese PF00581.20 GAX27493.1 - 4.4e-23 81.8 0.0 4.1e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain MgtC PF02308.16 GAX27494.1 - 1.2e-33 116.0 4.2 1.2e-33 116.0 4.2 1.6 2 0 0 2 2 2 1 MgtC family LRR_4 PF12799.7 GAX27495.1 - 0.0017 18.7 1.9 0.046 14.2 0.3 3.0 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAX27495.1 - 0.0078 16.2 5.0 0.75 10.0 0.1 3.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 GAX27495.1 - 0.009 15.8 2.7 0.022 14.5 0.4 2.8 3 1 0 3 3 3 1 Leucine rich repeat Pentapeptide_4 PF13599.6 GAX27495.1 - 0.011 15.9 0.7 0.52 10.5 0.2 2.9 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) SAGA-Tad1 PF12767.7 GAX27497.1 - 1.7 8.3 7.7 3.4 7.3 7.7 1.7 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ER_lumen_recept PF00810.18 GAX27498.1 - 1.4e-47 162.2 11.4 1.4e-47 162.2 11.4 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor Methyltransf_16 PF10294.9 GAX27499.1 - 3.1e-18 66.1 0.0 6.9e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 GAX27499.1 - 6.2e-11 42.3 0.0 9.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX27499.1 - 6.4e-10 39.1 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX27499.1 - 9.4e-07 29.5 0.0 1.8e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX27499.1 - 4.6e-06 26.3 0.0 9.6e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX27499.1 - 4.7e-06 27.2 0.0 9.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX27499.1 - 2.2e-05 25.0 0.0 4.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAX27499.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Dabb PF07876.12 GAX27499.1 - 0.096 13.3 0.0 0.3 11.7 0.0 1.8 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain CRCB PF02537.15 GAX27500.1 - 2.3e-31 107.9 12.2 3.3e-15 56.2 4.8 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) tRNA-synt_2 PF00152.20 GAX27501.1 - 1.4e-85 287.1 0.0 1.8e-85 286.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAX27501.1 - 1.3e-10 41.1 0.1 2.3e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX27501.1 - 0.0014 18.1 0.3 0.66 9.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF758 PF05527.11 GAX27501.1 - 0.048 13.7 0.5 0.09 12.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF758) adh_short_C2 PF13561.6 GAX27502.1 - 2.1e-53 181.3 0.0 2.4e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX27502.1 - 1.9e-38 131.9 0.0 2.3e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX27502.1 - 1.2e-15 57.9 0.3 1.6e-15 57.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Thioredoxin_15 PF18403.1 GAX27502.1 - 0.059 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Polysacc_synt_2 PF02719.15 GAX27502.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein APH PF01636.23 GAX27503.1 - 1e-18 68.2 2.7 1e-18 68.2 2.7 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX27503.1 - 1.9e-05 24.3 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 GAX27503.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 GAX27503.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Ank_2 PF12796.7 GAX27504.1 - 2.2e-13 50.6 0.1 8.1e-08 32.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX27504.1 - 1.3e-08 35.2 0.2 0.00031 21.3 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX27504.1 - 8.3e-08 32.4 0.0 4.1e-06 27.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX27504.1 - 1.4e-05 25.1 0.0 0.0033 17.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX27504.1 - 0.00018 21.8 0.0 1 9.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat ABC_tran_CTD PF16326.5 GAX27504.1 - 0.021 15.1 4.1 0.041 14.1 4.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain zf-CCCH PF00642.24 GAX27506.1 - 4.7e-10 39.1 7.0 1.1e-05 25.2 1.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAX27506.1 - 3.9e-07 29.9 9.3 0.00029 20.8 2.0 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAX27506.1 - 7.8e-07 28.8 8.0 0.0007 19.3 1.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 GAX27506.1 - 0.0019 18.9 4.2 0.15 12.8 1.0 2.7 1 1 1 2 2 2 2 Torus domain GED PF02212.18 GAX27506.1 - 0.23 11.6 2.9 0.49 10.6 2.9 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain zf-CCCH_2 PF14608.6 GAX27506.1 - 0.3 11.6 9.9 0.056 13.9 2.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 GAX27506.1 - 1.9 8.5 4.2 36 4.4 0.1 3.3 3 0 0 3 3 3 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 bZIP_1 PF00170.21 GAX27508.1 - 3.7e-07 30.1 9.1 3.7e-07 30.1 9.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX27508.1 - 0.00019 21.4 12.7 0.00019 21.4 12.7 2.2 2 0 0 2 2 2 1 Basic region leucine zipper Tup_N PF08581.10 GAX27508.1 - 0.0088 16.3 1.6 0.0088 16.3 1.6 1.7 2 0 0 2 2 2 1 Tup N-terminal Macoilin PF09726.9 GAX27508.1 - 0.023 13.3 9.6 0.027 13.0 9.6 1.0 1 0 0 1 1 1 0 Macoilin family Cep57_MT_bd PF06657.13 GAX27508.1 - 0.029 14.8 0.4 0.029 14.8 0.4 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 bZIP_Maf PF03131.17 GAX27508.1 - 0.033 14.7 6.3 0.033 14.7 6.3 2.1 2 1 0 2 2 2 0 bZIP Maf transcription factor XhlA PF10779.9 GAX27508.1 - 0.34 11.1 5.0 0.17 12.1 1.0 2.1 2 0 0 2 2 2 0 Haemolysin XhlA IFT57 PF10498.9 GAX27508.1 - 0.68 8.8 11.2 5.3 5.9 11.2 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 YlqD PF11068.8 GAX27508.1 - 1.1 9.7 6.2 0.14 12.6 2.3 1.5 2 0 0 2 2 2 0 YlqD protein Tho2 PF11262.8 GAX27508.1 - 2 7.5 10.6 5.5 6.1 10.6 1.8 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CASP_C PF08172.12 GAX27508.1 - 2.1 7.6 10.0 12 5.1 10.0 2.1 1 1 0 1 1 1 0 CASP C terminal DUF4140 PF13600.6 GAX27508.1 - 3.7 8.0 10.7 22 5.6 10.7 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 GAX27508.1 - 8.1 5.7 11.3 11 5.3 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 GAX27509.1 - 1.2e-08 35.0 6.0 1.2e-08 35.0 6.0 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX27509.1 - 4.1e-08 33.2 9.1 4.1e-08 33.2 9.1 1.9 2 0 0 2 2 2 1 Basic region leucine zipper MIP-T3_C PF17749.1 GAX27509.1 - 0.013 15.4 1.0 0.023 14.6 1.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region SR-25 PF10500.9 GAX27509.1 - 0.014 15.0 7.5 0.021 14.4 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IFT57 PF10498.9 GAX27509.1 - 0.045 12.7 1.3 0.15 11.0 1.3 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 BST2 PF16716.5 GAX27509.1 - 0.077 13.6 0.9 0.17 12.5 0.9 1.6 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF2203 PF09969.9 GAX27509.1 - 0.081 13.7 0.4 0.15 12.7 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) bZIP_Maf PF03131.17 GAX27509.1 - 0.42 11.2 11.0 0.057 14.0 6.1 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF3762 PF12591.8 GAX27509.1 - 0.68 10.2 6.0 31 4.9 0.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3762) Macoilin PF09726.9 GAX27509.1 - 1.3 7.4 10.2 4.1 5.8 10.3 1.6 1 1 0 1 1 1 0 Macoilin family Pur_ac_phosph_N PF16656.5 GAX27511.1 - 0.093 13.3 0.6 0.2 12.2 0.6 1.6 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Pkinase PF00069.25 GAX27512.1 - 4.7e-34 118.0 0.0 3.1e-33 115.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX27512.1 - 2.2e-31 109.1 0.0 3.2e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX27512.1 - 0.00096 19.1 0.1 0.0026 17.7 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX27512.1 - 0.0073 15.1 0.0 0.0097 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Thump_like PF18096.1 GAX27512.1 - 0.11 12.4 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 THUMP domain-like Plasmodium_HRP PF05403.11 GAX27515.1 - 3e-12 46.8 43.8 5.3e-07 29.7 15.3 3.9 1 1 2 3 3 3 2 Plasmodium histidine-rich protein (HRPII/III) ThiF PF00899.21 GAX27516.1 - 3.8e-64 216.4 0.0 5.5e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 GAX27516.1 - 4e-20 71.8 0.1 6.4e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Ecm33 PF12454.8 GAX27516.1 - 0.069 13.3 1.3 0.13 12.4 1.3 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Sacchrp_dh_NADP PF03435.18 GAX27516.1 - 0.085 13.1 0.3 4 7.7 0.0 3.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain FTSW_RODA_SPOVE PF01098.19 GAX27517.1 - 0.14 11.2 0.5 0.15 11.0 0.5 1.0 1 0 0 1 1 1 0 Cell cycle protein SIKE PF05769.11 GAX27518.1 - 0.18 11.8 2.4 0.55 10.1 2.5 1.8 1 1 0 1 1 1 0 SIKE family Aldose_epim PF01263.20 GAX27521.1 - 1.2e-85 287.5 0.3 1.3e-85 287.3 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Peptidase_S8 PF00082.22 GAX27522.1 - 1.2e-38 133.1 4.3 1.7e-37 129.3 4.3 2.0 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAX27522.1 - 0.05 14.3 0.6 0.11 13.1 0.6 1.6 1 1 0 1 1 1 0 Peptidase inhibitor I9 TraE PF05309.11 GAX27524.1 - 0.063 12.7 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 TraE protein DsrH PF04077.12 GAX27524.1 - 0.094 12.9 0.3 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 DsrH like protein zf-RVT PF13966.6 GAX27524.1 - 0.11 13.2 0.0 23 5.8 0.0 2.5 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Enterotoxin_ST PF02048.16 GAX27524.1 - 0.59 10.6 3.0 31 5.1 0.0 3.2 4 0 0 4 4 4 0 Heat-stable enterotoxin ST TB PF00683.17 GAX27524.1 - 3.7 7.4 5.5 25 4.7 0.4 2.5 2 0 0 2 2 2 0 TB domain Trypsin PF00089.26 GAX27525.1 - 6.5e-36 124.2 0.0 8.1e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Peptidase_S10 PF00450.22 GAX27526.1 - 6e-83 279.6 0.0 9.4e-83 278.9 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase N_methyl PF07963.12 GAX27526.1 - 0.12 12.0 3.3 0.2 11.3 3.3 1.3 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif TMEM65 PF10507.9 GAX27527.1 - 1.1e-38 131.5 2.7 1.9e-38 130.7 2.7 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 Romo1 PF10247.9 GAX27527.1 - 0.05 14.0 2.6 0.35 11.2 0.0 2.6 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 PT-VENN PF04829.13 GAX27527.1 - 0.28 11.3 2.9 34 4.6 0.0 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif ICAP-1_inte_bdg PF10480.9 GAX27529.1 - 0.27 11.2 3.0 0.41 10.6 3.0 1.1 1 0 0 1 1 1 0 Beta-1 integrin binding protein RVT_2 PF07727.14 GAX27530.1 - 3.8e-29 102.1 0.0 5.6e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX27530.1 - 0.00043 20.5 0.1 0.001 19.2 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Cnd1 PF12717.7 GAX27530.1 - 0.19 11.8 0.3 1.3 9.1 0.0 2.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TALPID3 PF15324.6 GAX27531.1 - 0.8 7.3 2.7 1 6.9 2.7 1.0 1 0 0 1 1 1 0 Hedgehog signalling target BRO1 PF03097.18 GAX27532.1 - 4e-18 65.4 0.1 5.1e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain O-FucT PF10250.9 GAX27533.1 - 1.7e-07 31.3 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase V-SNARE_C PF12352.8 GAX27534.1 - 1e-09 38.5 6.5 1e-09 38.5 6.5 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAX27534.1 - 1.5e-05 24.8 3.4 3.1e-05 23.8 0.5 2.5 1 1 2 3 3 3 1 Sec20 PLU-1 PF08429.11 GAX27534.1 - 0.00037 19.8 3.9 0.099 11.8 2.1 2.1 1 1 0 2 2 2 2 PLU-1-like protein DUF5319 PF17252.2 GAX27534.1 - 0.029 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5319) DUF5089 PF17002.5 GAX27534.1 - 0.033 14.1 0.6 0.058 13.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Synaptobrevin PF00957.21 GAX27534.1 - 0.08 12.7 0.6 0.14 11.9 0.6 1.5 1 0 0 1 1 1 0 Synaptobrevin Prominin PF05478.11 GAX27534.1 - 0.12 10.3 2.9 0.16 9.9 2.9 1.2 1 0 0 1 1 1 0 Prominin DUF5127 PF17168.4 GAX27534.1 - 0.17 11.7 0.2 0.27 11.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) TMPIT PF07851.13 GAX27534.1 - 0.21 10.8 3.3 0.19 11.0 0.8 1.8 1 1 1 2 2 2 0 TMPIT-like protein DUF745 PF05335.13 GAX27534.1 - 4.6 6.9 11.2 4 7.1 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PI3_PI4_kinase PF00454.27 GAX27535.1 - 2.8e-33 115.8 0.3 8e-31 107.7 0.3 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAX27535.1 - 0.0029 17.0 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PalH PF08733.10 GAX27535.1 - 0.14 11.1 0.1 0.26 10.2 0.1 1.3 1 0 0 1 1 1 0 PalH/RIM21 DUF2975 PF11188.8 GAX27535.1 - 0.24 11.3 3.5 2.1 8.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Ank_2 PF12796.7 GAX27536.1 - 1.6e-23 83.1 0.1 7.3e-12 45.7 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX27536.1 - 3.9e-18 65.6 0.1 3.8e-10 40.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX27536.1 - 9.4e-18 64.1 0.1 1.4e-07 31.6 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX27536.1 - 6.5e-17 61.1 0.1 0.002 18.5 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 GAX27536.1 - 2.6e-16 58.0 0.0 0.0038 17.6 0.0 5.5 4 1 0 4 4 4 3 Ankyrin repeat DUF1736 PF08409.11 GAX27536.1 - 0.029 14.3 0.0 0.09 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1736) PFK PF00365.20 GAX27537.1 - 1.8e-31 109.5 0.3 9.4e-31 107.2 0.3 1.8 1 1 0 1 1 1 1 Phosphofructokinase HMG_box PF00505.19 GAX27538.1 - 6e-09 36.2 5.2 3.6e-08 33.7 5.2 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27538.1 - 8e-07 29.6 2.6 8e-07 29.6 2.6 2.1 2 0 0 2 2 2 1 HMG-box domain An_peroxidase PF03098.15 GAX27538.1 - 0.078 11.5 0.3 0.14 10.7 0.3 1.4 1 0 0 1 1 1 0 Animal haem peroxidase YABBY PF04690.13 GAX27538.1 - 0.94 10.0 4.4 0.54 10.8 1.1 2.2 2 0 0 2 2 2 0 YABBY protein MFS_1_like PF12832.7 GAX27539.1 - 1e-52 179.3 10.6 6.9e-52 176.6 10.6 2.1 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAX27539.1 - 4.1e-21 75.3 32.2 2.4e-17 62.9 14.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 GAX27539.1 - 1.4e-16 60.5 5.8 4.5e-12 45.7 2.2 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 GAX27539.1 - 1.7e-05 23.8 0.2 1.7e-05 23.8 0.2 2.3 2 0 0 2 2 2 1 LacY proton/sugar symporter HCO3_cotransp PF00955.21 GAX27540.1 - 7e-108 361.7 19.7 5e-69 233.5 1.0 2.7 1 1 1 2 2 2 2 HCO3- transporter family MFS_MOT1 PF16983.5 GAX27540.1 - 2.4 8.6 9.8 3.2 8.2 1.7 3.0 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily WW PF00397.26 GAX27541.1 - 0.00034 20.6 3.1 0.001 19.1 3.1 1.9 1 0 0 1 1 1 1 WW domain HCO3_cotransp PF00955.21 GAX27542.1 - 5e-106 355.5 18.6 3.3e-67 227.5 1.2 2.7 2 1 0 2 2 2 2 HCO3- transporter family MFS_MOT1 PF16983.5 GAX27542.1 - 3.2 8.2 10.0 4.6 7.7 2.3 3.1 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily HCO3_cotransp PF00955.21 GAX27543.1 - 5.5e-54 183.8 10.7 1.9e-37 129.3 1.5 3.0 2 1 1 3 3 3 3 HCO3- transporter family Amino_oxidase PF01593.24 GAX27544.1 - 1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX27544.1 - 3.1e-07 30.5 0.0 6.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAX27544.1 - 1.9e-06 28.3 0.0 0.0019 18.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAX27544.1 - 4.1e-06 26.3 0.1 3.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX27544.1 - 1.2e-05 24.8 0.0 2.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 GAX27544.1 - 3.5e-05 23.1 0.5 0.012 14.7 0.6 2.5 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 GAX27544.1 - 0.00039 19.6 0.3 0.00039 19.6 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAX27544.1 - 0.00067 19.1 3.0 0.0013 18.1 1.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX27544.1 - 0.0066 15.2 0.2 0.01 14.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 GAX27544.1 - 0.037 13.9 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAX27544.1 - 0.051 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 GAX27544.1 - 0.053 13.1 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GAX27544.1 - 0.063 13.7 0.0 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 GAX27544.1 - 0.11 11.4 0.2 0.17 10.7 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Peptidase_S28 PF05577.12 GAX27545.1 - 6.4e-66 222.9 10.7 7.2e-62 209.6 0.2 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 GAX27545.1 - 0.0033 17.1 0.1 0.0066 16.1 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 GAX27545.1 - 0.032 13.4 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Hydrolase_4 PF12146.8 GAX27545.1 - 0.035 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_M41 PF01434.18 GAX27548.1 - 3.9e-61 206.3 0.0 6.4e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAX27548.1 - 1.8e-42 144.9 0.0 5.4e-42 143.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX27548.1 - 2.5e-13 49.6 0.3 6.8e-13 48.2 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAX27548.1 - 0.00037 20.8 0.1 0.053 13.8 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX27548.1 - 0.0007 19.6 0.2 0.012 15.7 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAX27548.1 - 0.00078 18.7 0.1 0.0016 17.7 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GAX27548.1 - 0.0032 17.2 0.0 0.01 15.6 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX27548.1 - 0.0037 17.4 0.0 0.009 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsH_ext PF06480.15 GAX27548.1 - 0.012 16.0 0.0 0.05 14.0 0.0 2.1 1 0 0 1 1 1 0 FtsH Extracellular IstB_IS21 PF01695.17 GAX27548.1 - 0.018 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 GAX27548.1 - 0.026 15.1 0.1 0.33 11.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 GAX27548.1 - 0.035 13.5 0.1 0.086 12.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 GAX27548.1 - 0.052 13.7 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Cep57_MT_bd PF06657.13 GAX27548.1 - 0.082 13.4 0.3 0.21 12.1 0.3 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 AAA_28 PF13521.6 GAX27548.1 - 0.091 13.0 2.2 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 GAX27548.1 - 0.098 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX27548.1 - 0.16 12.3 3.7 0.51 10.7 1.3 3.1 2 1 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.7 GAX27549.1 - 9.3e-08 32.6 0.0 6.8e-07 29.8 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX27549.1 - 1.9e-07 31.2 0.2 0.024 14.9 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX27549.1 - 3.1e-06 27.6 0.4 0.0041 17.7 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX27549.1 - 0.0006 20.1 0.0 0.0097 16.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAX27549.1 - 0.11 13.0 0.0 8.5 7.0 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat HMG_box PF00505.19 GAX27550.1 - 1.9e-10 41.0 3.5 2.1e-09 37.7 3.5 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX27550.1 - 3.8e-08 33.8 2.3 1.3e-07 32.1 2.3 2.0 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 GAX27550.1 - 1.2 9.7 9.6 0.08 13.5 2.8 2.3 2 1 0 2 2 2 0 YABBY protein DUF4100 PF13352.6 GAX27550.1 - 1.3 8.8 5.3 2.7 7.7 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) DUF2722 PF10846.8 GAX27551.1 - 0.012 14.6 5.5 0.016 14.2 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RNA_pol_3_Rpc31 PF11705.8 GAX27551.1 - 0.017 15.4 20.5 0.033 14.5 20.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 GAX27551.1 - 0.03 13.7 19.4 0.043 13.2 19.4 1.2 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 GAX27551.1 - 0.034 14.0 8.9 0.052 13.4 8.9 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 GAX27551.1 - 0.2 9.8 31.0 0.26 9.4 31.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF5345 PF17280.2 GAX27551.1 - 2.8 8.0 4.6 0.68 10.0 0.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Pes-10 PF07149.11 GAX27551.1 - 3.4 6.6 24.6 5 6.1 24.6 1.2 1 0 0 1 1 1 0 Pes-10 PA26 PF04636.13 GAX27551.1 - 4.8 6.0 6.4 7 5.4 6.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TFIIA PF03153.13 GAX27551.1 - 7.6 6.4 20.8 0.71 9.8 16.7 1.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAX27551.1 - 8.3 5.1 8.2 11 4.6 8.2 1.1 1 0 0 1 1 1 0 Presenilin PAP_fibrillin PF04755.12 GAX27552.1 - 0.001 19.0 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 PAP_fibrillin RabGAP-TBC PF00566.18 GAX27553.1 - 2.7e-11 43.6 0.4 2.7e-11 43.6 0.4 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain LRAT PF04970.13 GAX27554.1 - 0.00018 21.8 0.8 0.00034 20.9 0.0 1.9 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DUF572 PF04502.13 GAX27554.1 - 6.5 6.3 9.4 0.83 9.2 0.4 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF572) Cys_Met_Meta_PP PF01053.20 GAX27555.1 - 9e-30 103.5 0.0 1.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 GAX27555.1 - 0.01 14.5 0.0 0.077 11.6 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-III EamA PF00892.20 GAX27556.1 - 7.7e-19 68.2 9.9 4.2e-09 36.7 0.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family ABM PF03992.16 GAX27557.1 - 5.2e-16 58.5 0.3 7.7e-16 58.0 0.3 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Peptidase_M48 PF01435.18 GAX27558.1 - 1.3e-22 80.5 0.2 2.6e-22 79.5 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M48 FAA_hydrolase_N PF09298.11 GAX27558.1 - 0.025 14.8 0.1 0.056 13.6 0.1 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal DUF5010 PF16402.5 GAX27558.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) ABC_tran PF00005.27 GAX27559.1 - 2e-22 80.2 0.0 6e-22 78.6 0.0 1.8 2 0 0 2 2 1 1 ABC transporter ABC2_membrane PF01061.24 GAX27559.1 - 1.2e-19 70.6 3.1 2.1e-19 69.8 3.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GAX27559.1 - 2.5e-05 24.2 0.7 0.19 11.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 GAX27559.1 - 8.3e-05 22.0 0.0 0.00017 21.0 0.0 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 GAX27559.1 - 0.00028 20.4 2.3 0.61 9.5 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAX27559.1 - 0.00094 19.6 0.3 0.0035 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAX27559.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GAX27559.1 - 0.0024 17.6 0.1 0.0057 16.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 GAX27559.1 - 0.003 16.7 2.3 0.0057 15.8 2.3 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.6 GAX27559.1 - 0.0059 16.2 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 GAX27559.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAX27559.1 - 0.016 15.4 0.6 0.18 12.0 0.0 2.9 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 GAX27559.1 - 0.03 14.7 0.1 5.2 7.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 GAX27559.1 - 0.049 14.2 0.0 0.18 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 GAX27559.1 - 0.064 12.2 0.1 0.24 10.3 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 GAX27559.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 GAX27559.1 - 0.14 12.7 0.3 0.14 12.7 0.3 2.1 2 0 0 2 2 2 0 AAA domain SNARE_assoc PF09335.11 GAX27559.1 - 0.42 11.1 6.9 0.85 10.1 5.3 2.3 2 0 0 2 2 2 0 SNARE associated Golgi protein Peptidase_M41 PF01434.18 GAX27560.1 - 8.9e-61 205.1 0.1 1.5e-60 204.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAX27560.1 - 2.9e-42 144.2 0.0 1.2e-41 142.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX27560.1 - 4.5e-14 52.0 0.2 9.7e-14 50.9 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAX27560.1 - 1.7e-06 28.1 0.8 0.0098 15.9 0.0 4.0 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX27560.1 - 0.00032 21.0 1.0 0.056 13.7 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAX27560.1 - 0.0016 18.6 0.1 0.009 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsH_ext PF06480.15 GAX27560.1 - 0.0016 18.8 0.0 0.0046 17.3 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 GAX27560.1 - 0.0029 16.9 0.1 0.0029 16.9 0.1 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 GAX27560.1 - 0.0034 17.1 0.0 0.0099 15.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAX27560.1 - 0.0035 17.5 0.1 0.05 13.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAX27560.1 - 0.017 15.5 4.3 0.061 13.7 1.3 3.4 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 GAX27560.1 - 0.017 14.9 0.0 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 GAX27560.1 - 0.026 15.1 0.3 0.33 11.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 GAX27560.1 - 0.061 12.7 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad60-SLD PF11976.8 GAX27560.1 - 0.081 12.8 2.3 4.5 7.2 0.4 2.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like AAA_17 PF13207.6 GAX27560.1 - 0.14 12.6 0.3 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAX27560.1 - 0.15 12.3 1.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 GAX27560.1 - 0.17 10.9 0.0 0.45 9.6 0.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Zeta_toxin PF06414.12 GAX27560.1 - 0.18 11.1 2.1 3.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin Proteasome PF00227.26 GAX27561.1 - 1.1e-32 113.0 0.2 1.4e-32 112.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit P5CR_dimer PF14748.6 GAX27562.1 - 7.3e-34 116.1 0.0 1.6e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAX27562.1 - 9e-12 45.4 0.0 1.5e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAX27562.1 - 8.3e-05 22.8 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 GAX27562.1 - 0.0025 17.9 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAX27562.1 - 0.0049 16.2 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 GAX27562.1 - 0.012 16.5 0.0 0.035 14.9 0.0 1.9 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 GAX27562.1 - 0.032 14.7 0.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1421 PF07223.11 GAX27562.1 - 0.057 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain (DUF1421) DpaA_N PF16924.5 GAX27562.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain Metallophos PF00149.28 GAX27564.1 - 1.7e-19 71.1 1.3 3.4e-19 70.2 1.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAX27564.1 - 1.9e-11 44.3 0.3 4.5e-11 43.2 0.3 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GAX27564.1 - 2.9e-10 40.9 0.3 1.1e-09 39.1 0.1 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 GAX27564.1 - 5.3e-05 23.5 0.1 0.25 11.6 0.1 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 GAX27564.1 - 0.1 13.1 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Thioredoxin_2 PF13098.6 GAX27566.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain CbtB PF09489.10 GAX27566.1 - 0.19 11.9 1.0 0.51 10.5 1.0 1.7 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Proteasome PF00227.26 GAX27567.1 - 3.4e-59 199.6 0.0 3.9e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX27567.1 - 8.1e-10 38.2 0.1 3.7e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Cyclin_N PF00134.23 GAX27568.1 - 1.9e-17 63.2 0.3 2.8e-17 62.6 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain FAD_binding_3 PF01494.19 GAX27569.1 - 1.8e-23 83.4 0.8 2.4e-10 40.2 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 GAX27569.1 - 1.5e-05 24.2 0.0 3.7e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 GAX27569.1 - 9.8e-05 22.1 0.4 0.00037 20.2 0.3 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX27569.1 - 0.001 18.2 1.1 0.016 14.3 0.3 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 GAX27569.1 - 0.0024 17.1 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAX27569.1 - 0.0026 17.9 0.1 0.01 16.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAX27569.1 - 0.0029 16.5 0.1 0.077 11.8 0.0 2.4 2 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 GAX27569.1 - 0.0038 16.5 0.0 0.032 13.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX27569.1 - 0.039 14.5 0.0 0.12 13.0 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 GAX27569.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) GATase PF00117.28 GAX27570.1 - 3.3e-10 40.1 0.0 4.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GAX27570.1 - 0.029 13.9 0.0 0.068 12.8 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain CARD PF00619.21 GAX27570.1 - 0.071 13.2 0.2 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Caspase recruitment domain SNF2_N PF00176.23 GAX27571.1 - 2.1e-51 174.7 0.9 4.3e-51 173.7 0.9 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pro_isomerase PF00160.21 GAX27571.1 - 4.4e-48 163.5 0.3 8.1e-48 162.7 0.3 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Helicase_C PF00271.31 GAX27571.1 - 6.7e-06 26.4 0.0 2.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX27571.1 - 0.061 13.3 0.0 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HSP20 PF00011.21 GAX27572.1 - 9e-20 70.7 0.1 1.2e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAX27572.1 - 0.00016 21.2 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Mitofilin PF09731.9 GAX27573.1 - 0.11 11.3 12.4 0.2 10.5 12.4 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Telomerase_RBD PF12009.8 GAX27575.1 - 3.3e-28 98.4 2.1 1e-27 96.9 2.1 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 GAX27575.1 - 4.4e-11 42.7 0.1 1.5e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.15 GAX27576.1 - 3.6e-11 42.9 0.6 6.5e-11 42.1 0.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAX27576.1 - 0.00011 22.9 0.6 0.00016 22.4 0.6 1.4 1 1 0 1 1 1 1 Complex1_LYR-like MIT PF04212.18 GAX27576.1 - 0.014 15.4 0.8 0.43 10.7 0.0 2.3 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain Bromodomain PF00439.25 GAX27577.1 - 9.2e-23 80.1 0.0 2.9e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Bromodomain SDA1 PF05285.12 GAX27577.1 - 0.0013 18.3 7.5 0.0016 17.9 7.5 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GAX27577.1 - 0.018 14.4 6.7 0.021 14.2 6.7 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAX27577.1 - 0.019 13.2 10.1 0.022 13.0 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAX27577.1 - 0.027 12.8 5.5 0.031 12.6 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 GAX27577.1 - 0.029 14.3 4.7 0.047 13.7 4.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RRN3 PF05327.11 GAX27577.1 - 0.25 9.8 11.2 0.38 9.3 11.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 GAX27577.1 - 1.5 8.1 17.3 0.99 8.7 15.4 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT eIF-3c_N PF05470.12 GAX27577.1 - 4.1 5.6 7.8 6.2 5.0 7.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 GAX27577.1 - 5.2 6.3 14.4 7.6 5.7 14.4 1.3 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 GAX27577.1 - 5.4 5.0 6.7 7.2 4.6 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med26 PF08711.11 GAX27578.1 - 1.5e-08 34.6 0.1 4.2e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain p450 PF00067.22 GAX27579.1 - 1e-47 163.0 0.0 1.3e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_4 PF08007.12 GAX27581.1 - 1.7e-32 113.2 3.5 1.1e-31 110.5 3.5 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 GAX27581.1 - 7.4e-06 25.9 3.5 1.7e-05 24.7 1.2 2.4 2 1 0 2 2 2 1 Cupin-like domain Mito_carr PF00153.27 GAX27582.1 - 5e-70 231.5 2.0 4.8e-23 80.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX27582.1 - 0.0011 18.2 2.8 0.61 9.2 0.3 3.2 2 1 1 3 3 3 3 Gammaproteobacterial serine protease NUMOD3 PF07460.11 GAX27583.1 - 0.099 12.9 0.6 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) Beach PF02138.18 GAX27584.1 - 5.8e-117 390.0 0.0 1.1e-116 389.0 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAX27584.1 - 9.7e-18 64.1 0.0 4.1e-17 62.1 0.0 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 GAX27584.1 - 4.5e-08 32.7 0.2 1.3e-07 31.1 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) WD40 PF00400.32 GAX27584.1 - 1.2e-06 29.1 7.7 0.12 13.3 0.1 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX27584.1 - 0.0057 16.9 0.0 15 6.0 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Med27 PF11571.8 GAX27585.1 - 0.0074 16.6 0.4 0.016 15.5 0.4 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 MCU PF04678.13 GAX27585.1 - 0.57 10.3 2.5 0.96 9.5 1.3 1.9 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF547 PF04784.14 GAX27586.1 - 1.6e-14 54.0 0.0 3.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 PH PF00169.29 GAX27586.1 - 0.12 12.9 1.5 0.7 10.4 0.0 2.9 3 1 0 4 4 4 0 PH domain Anoctamin PF04547.12 GAX27587.1 - 1.2e-99 334.2 18.4 1.6e-99 333.8 18.4 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 GAX27587.1 - 0.0024 17.6 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin UCH PF00443.29 GAX27588.1 - 4.6e-61 206.5 0.0 1.1e-60 205.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAX27588.1 - 1.4e-15 57.7 0.2 1.4e-14 54.5 0.1 2.5 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 GAX27588.1 - 3.3e-15 56.5 3.8 2e-07 30.9 0.0 3.8 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase zf-RING_5 PF14634.6 GAX27589.1 - 1.7e-07 31.1 11.4 3.5e-07 30.1 11.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAX27589.1 - 4.1e-07 30.2 12.1 1.1e-06 28.9 12.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX27589.1 - 9.9e-07 28.5 12.1 2.2e-06 27.4 12.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX27589.1 - 1.3e-06 28.3 5.9 1.3e-06 28.3 5.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX27589.1 - 5.7e-06 26.1 12.3 1.2e-05 25.1 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT_3 PF18428.1 GAX27589.1 - 7.3e-06 26.0 0.5 0.21 11.7 0.0 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4_4 PF15227.6 GAX27589.1 - 0.00027 21.0 13.2 0.00056 20.0 13.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAX27589.1 - 0.00041 20.3 5.8 0.00085 19.3 5.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAX27589.1 - 0.00056 19.7 8.4 0.0016 18.3 8.4 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAX27589.1 - 0.00097 19.4 5.5 0.0024 18.1 5.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain BRCT_2 PF16589.5 GAX27589.1 - 0.0053 17.1 0.0 5.8 7.4 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-Nse PF11789.8 GAX27589.1 - 0.074 12.9 5.8 0.2 11.5 5.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAX27589.1 - 0.11 12.4 16.0 0.45 10.4 15.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 NapD PF03927.13 GAX27589.1 - 0.12 12.5 0.2 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 NapD protein zf-C3HC4_5 PF17121.5 GAX27589.1 - 1 9.3 11.2 3.7 7.5 11.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAX27589.1 - 1.3 8.7 9.1 2.7 7.7 9.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 GAX27589.1 - 2.7 7.9 5.5 29 4.6 0.2 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif VWD PF00094.25 GAX27590.1 - 0.0003 21.1 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain RGM_C PF06534.13 GAX27590.1 - 0.00058 19.4 0.4 0.0017 17.9 0.1 1.9 3 0 0 3 3 3 1 Repulsive guidance molecule (RGM) C-terminus Trypsin_2 PF13365.6 GAX27591.1 - 7.7e-26 91.8 0.0 3.7e-25 89.6 0.0 2.1 3 1 0 3 3 3 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX27591.1 - 1.7e-09 37.8 0.0 4.9e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Trypsin PDZ_2 PF13180.6 GAX27591.1 - 1.7e-07 31.4 0.0 6.5e-07 29.6 0.0 2.0 3 0 0 3 3 3 1 PDZ domain Peptidase_S29 PF02907.15 GAX27591.1 - 0.00093 19.0 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease PDZ_6 PF17820.1 GAX27591.1 - 0.0013 18.5 0.0 0.92 9.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Peptidase_S7 PF00949.21 GAX27591.1 - 0.0014 18.5 0.3 0.0036 17.1 0.3 1.7 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 GAX27591.1 - 0.0031 17.1 0.5 0.84 9.1 0.0 2.4 3 0 0 3 3 3 2 Putative peptidase (DUF31) GRASP55_65 PF04495.14 GAX27591.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Peptidase_S46 PF10459.9 GAX27591.1 - 0.023 13.4 0.1 0.036 12.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase S46 PDZ PF00595.24 GAX27591.1 - 0.038 14.4 0.0 0.46 10.9 0.0 2.5 1 1 0 1 1 1 0 PDZ domain GTP_EFTU PF00009.27 GAX27592.1 - 3.9e-48 163.6 0.0 5.6e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 GAX27592.1 - 3.4e-41 140.2 0.0 6.1e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 GAX27592.1 - 2.5e-05 24.6 0.0 4.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAX27592.1 - 4.8e-05 23.4 0.0 9.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAX27592.1 - 6.2e-05 23.0 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Filamin PF00630.19 GAX27595.1 - 0.075 13.9 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Filamin/ABP280 repeat FTHFS PF01268.19 GAX27596.1 - 1.1e-250 832.6 0.3 1.3e-250 832.4 0.3 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 GAX27596.1 - 0.014 15.4 1.0 0.042 13.9 0.5 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Choline_transpo PF04515.12 GAX27597.1 - 1.2e-57 195.6 19.5 1.2e-57 195.6 19.5 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter Nnf1 PF03980.14 GAX27597.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Nnf1 MARVEL PF01284.23 GAX27598.1 - 0.0011 19.0 39.1 0.012 15.6 16.2 3.5 1 1 2 3 3 3 1 Membrane-associating domain Astro_capsid_p PF12226.8 GAX27598.1 - 1.6 7.8 6.7 2.5 7.2 6.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF308 PF03729.13 GAX27598.1 - 3.3 8.1 0.0 3.3 8.1 0.0 5.1 4 2 1 5 5 5 0 Short repeat of unknown function (DUF308) Ank_2 PF12796.7 GAX27599.1 - 3.1e-09 37.3 0.5 0.0017 18.9 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX27599.1 - 1.1e-08 34.7 3.0 1.5 9.6 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 GAX27599.1 - 6.2e-08 33.0 2.3 0.0073 16.9 0.1 4.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX27599.1 - 4.2e-05 23.7 0.0 0.05 13.9 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX27599.1 - 0.00014 22.1 7.7 1.3 9.6 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeat tRNA_bind_3 PF17176.4 GAX27599.1 - 1.1 9.5 4.4 69 3.8 3.3 3.2 2 1 0 2 2 2 0 tRNA-binding domain Ceramidase PF05875.12 GAX27600.1 - 9.4e-33 113.7 5.8 1.3e-32 113.2 5.8 1.2 1 0 0 1 1 1 1 Ceramidase SirB PF04247.12 GAX27600.1 - 0.82 9.8 5.2 1.9 8.6 0.2 2.6 2 1 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF3611 PF12263.8 GAX27601.1 - 2.5e-39 135.0 8.6 3.5e-39 134.5 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) DUF4395 PF14340.6 GAX27601.1 - 0.023 15.0 2.3 0.087 13.2 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) PWI PF01480.17 GAX27602.1 - 1.1e-06 28.9 0.1 1.8e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 PWI domain DUF839 PF05787.13 GAX27603.1 - 4.5e-12 45.9 4.7 3.4e-07 29.8 2.1 2.9 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF839) OAD_gamma PF04277.13 GAX27603.1 - 0.2 12.3 0.2 0.37 11.4 0.2 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF839 PF05787.13 GAX27604.1 - 5.1e-12 45.7 4.2 1.7e-07 30.8 2.1 2.9 2 1 1 3 3 3 3 Bacterial protein of unknown function (DUF839) DUF4661 PF15576.6 GAX27605.1 - 6.2 6.7 6.9 0.31 10.9 1.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4661) Elf1 PF05129.13 GAX27608.1 - 3.4e-27 94.3 1.1 4.9e-27 93.8 1.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like CcmH PF03918.14 GAX27608.1 - 0.042 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Lar_restr_allev PF14354.6 GAX27608.1 - 0.72 10.3 5.0 2 8.8 5.0 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.15 GAX27608.1 - 1.7 8.8 5.1 8.5 6.5 0.7 2.6 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Mito_carr PF00153.27 GAX27609.1 - 3.1e-52 174.5 0.8 5.5e-18 64.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mit_KHE1 PF10173.9 GAX27609.1 - 0.044 13.9 0.1 0.079 13.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related LRR_4 PF12799.7 GAX27610.1 - 7.3e-09 35.8 8.5 0.0012 19.2 0.5 5.7 3 3 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX27610.1 - 8.3e-08 31.9 4.2 0.00058 19.6 0.2 4.2 3 2 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 GAX27610.1 - 0.00046 20.3 3.2 24 6.0 0.1 5.9 6 2 0 6 6 6 1 Leucine Rich Repeat TLD PF07534.16 GAX27611.1 - 0.0001 22.5 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 TLD DUF563 PF04577.14 GAX27612.1 - 0.0038 17.4 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) COG4 PF08318.12 GAX27613.1 - 0.0019 17.4 0.2 0.13 11.3 0.2 2.5 1 1 0 1 1 1 1 COG4 transport protein CENP-B_dimeris PF09026.10 GAX27613.1 - 0.11 12.9 3.8 0.31 11.4 1.9 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Tail_P2_I PF09684.10 GAX27613.1 - 0.28 11.1 3.0 9.2 6.2 0.0 3.3 2 1 1 3 3 3 0 Phage tail protein (Tail_P2_I) DUF4611 PF15387.6 GAX27613.1 - 4.2 7.7 6.7 0.65 10.3 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) E1_dh PF00676.20 GAX27614.1 - 4.8e-98 327.8 0.2 5.7e-98 327.6 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAX27614.1 - 0.0032 16.7 0.4 0.0085 15.3 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase MMR_HSR1 PF01926.23 GAX27615.1 - 5.3e-18 65.2 0.0 1.9e-16 60.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX27615.1 - 6.1e-07 29.1 0.0 1.5e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 GAX27615.1 - 0.00078 18.5 1.8 0.015 14.3 0.0 2.3 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAX27615.1 - 0.01 15.9 2.1 0.021 14.9 0.1 2.5 2 1 1 3 3 3 0 Dynamin family SRPRB PF09439.10 GAX27615.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 GAX27615.1 - 0.028 13.8 0.0 0.084 12.2 0.0 1.8 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 GAX27615.1 - 0.035 13.6 0.1 5.6 6.4 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 GAX27615.1 - 0.056 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAX27615.1 - 0.085 12.7 0.2 0.28 11.1 0.1 1.8 1 1 0 2 2 2 0 RsgA GTPase GDPD PF03009.17 GAX27617.1 - 1.4e-13 51.2 0.0 6.5e-13 49.0 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RexA PF15969.5 GAX27617.1 - 0.057 13.0 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component Kelch_5 PF13854.6 GAX27618.1 - 5.1e-15 55.1 0.8 0.0028 17.6 0.0 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 GAX27618.1 - 4.1e-14 51.9 0.3 0.00088 19.2 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAX27618.1 - 1.5e-12 47.3 9.7 6.9e-05 22.8 0.0 5.7 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX27618.1 - 1e-10 41.5 5.8 0.014 15.7 0.1 5.4 2 2 3 5 5 5 4 Kelch motif Kelch_3 PF13415.6 GAX27618.1 - 1.6e-08 34.6 12.2 0.0003 21.0 0.0 5.8 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAX27618.1 - 0.00031 20.3 9.1 0.83 9.3 0.0 4.9 4 2 0 4 4 4 2 Kelch motif Arm PF00514.23 GAX27619.1 - 2.3e-11 43.3 3.6 1.9e-05 24.5 0.1 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 GAX27619.1 - 0.00033 20.6 0.2 0.05 13.6 0.3 3.7 1 1 2 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 GAX27619.1 - 0.0028 17.8 2.0 5.2 7.6 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 GAX27619.1 - 0.017 15.6 1.3 9.8 6.8 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat DNA_pol_B_palm PF14792.6 GAX27620.1 - 4.4e-19 68.8 0.0 5.9e-17 61.9 0.0 2.6 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 GAX27620.1 - 8.6e-13 48.3 0.0 2.7e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GAX27620.1 - 1.8e-11 43.7 0.0 7.5e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.23 GAX27620.1 - 0.0018 18.6 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_8 PF14716.6 GAX27620.1 - 0.003 17.9 0.0 0.0069 16.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 GAX27620.1 - 0.018 15.6 0.1 0.3 11.7 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain SapB_1 PF05184.15 GAX27620.1 - 0.31 11.1 1.4 1.3 9.1 0.4 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 1 DNA_pol_B_palm PF14792.6 GAX27621.1 - 1.5e-19 70.3 0.0 7.7e-18 64.8 0.0 2.6 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 GAX27621.1 - 5.6e-15 55.3 0.1 1.3e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GAX27621.1 - 9.3e-13 47.8 0.0 5.3e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 GAX27621.1 - 2e-08 34.5 0.0 4.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 GAX27621.1 - 0.00089 19.8 0.0 0.24 12.0 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 GAX27621.1 - 0.00097 19.4 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Caudo_bapla16 PF16792.5 GAX27621.1 - 0.0049 15.9 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Phage tail base-plate attachment protein of Caudovirales ORF16 Hydantoinase_B PF02538.14 GAX27622.1 - 1.3e-211 703.5 0.7 1.7e-211 703.2 0.7 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAX27622.1 - 9.6e-100 333.6 0.0 1.8e-99 332.7 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAX27622.1 - 1.3e-53 181.3 0.0 1.3e-51 174.8 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF601 PF04642.12 GAX27623.1 - 6.6 6.1 7.1 20 4.6 1.3 2.1 1 1 2 3 3 3 0 Protein of unknown function, DUF601 Sulfate_transp PF00916.20 GAX27624.1 - 5.5e-09 35.3 8.8 5.5e-05 22.1 3.8 2.4 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 GAX27624.1 - 6.5e-09 35.4 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAX27624.1 - 0.00063 20.0 0.0 0.0025 18.1 0.0 2.1 1 0 0 1 1 1 1 STAS domain NAD_binding_1 PF00175.21 GAX27626.1 - 3.6e-14 53.3 0.0 6.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAX27626.1 - 0.00018 21.8 0.0 0.00032 21.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain E1-E2_ATPase PF00122.20 GAX27627.1 - 3.2e-48 163.6 0.8 1.2e-47 161.8 0.7 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAX27627.1 - 1.1e-14 55.2 1.2 6.3e-14 52.8 1.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX27627.1 - 3.6e-10 39.4 0.0 1.4e-09 37.5 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAX27627.1 - 0.00045 20.0 0.6 0.0011 18.7 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAX27627.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2975 PF11188.8 GAX27627.1 - 0.09 12.7 11.8 0.45 10.4 1.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2975) bZIP_1 PF00170.21 GAX27628.1 - 1.6e-11 44.1 12.9 2.3e-11 43.6 12.9 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAX27628.1 - 3.1e-08 33.6 14.9 4.5e-08 33.0 14.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAX27628.1 - 6.6e-05 23.4 5.7 9.3e-05 22.9 5.7 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor BTAD PF03704.17 GAX27628.1 - 0.002 18.6 0.3 0.0028 18.1 0.3 1.2 1 0 0 1 1 1 1 Bacterial transcriptional activator domain NRBF2 PF08961.10 GAX27628.1 - 0.022 14.4 2.4 0.031 13.9 2.4 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 GAX27628.1 - 0.047 14.3 0.2 0.055 14.1 0.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA GIT_CC PF16559.5 GAX27628.1 - 0.067 13.1 0.3 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor LMBR1 PF04791.16 GAX27628.1 - 0.13 11.2 0.2 0.13 11.1 0.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Tho2 PF11262.8 GAX27628.1 - 0.21 10.8 1.2 0.25 10.5 1.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CDC45 PF02724.14 GAX27628.1 - 0.58 8.4 7.4 0.66 8.2 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein XAP5 PF04921.14 GAX27628.1 - 0.78 9.5 7.7 0.95 9.2 7.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator LRR_4 PF12799.7 GAX27631.1 - 1e-13 51.2 18.3 0.0068 16.8 0.1 6.1 3 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX27631.1 - 1.1e-10 41.1 16.9 0.00026 20.7 6.9 4.9 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 GAX27631.1 - 9.7e-09 34.6 11.0 0.17 12.6 0.1 7.4 6 2 0 6 6 6 3 Leucine Rich Repeat DUF4366 PF14283.6 GAX27631.1 - 0.24 11.5 0.0 0.51 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2428 PF10350.9 GAX27632.1 - 9.8e-29 100.5 0.2 2.1e-28 99.4 0.2 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 GAX27632.1 - 0.097 13.0 0.3 3.1 8.3 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 GAX27632.1 - 1.1 9.9 3.6 2.6 8.7 0.1 3.6 3 0 0 3 3 3 0 HEAT-like repeat Lipase_GDSL_2 PF13472.6 GAX27633.1 - 1e-11 45.5 0.0 2.2e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX27633.1 - 1.1e-07 32.1 0.0 1.4e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MBG_2 PF18676.1 GAX27633.1 - 0.085 13.5 0.2 0.16 12.6 0.2 1.5 1 0 0 1 1 1 0 MBG domain (YGX type) Ion_trans_2 PF07885.16 GAX27634.1 - 4.7e-16 58.5 25.5 2.9e-10 40.0 5.6 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 GAX27634.1 - 0.00058 19.2 17.2 0.017 14.4 5.6 2.5 2 1 0 2 2 2 2 Ion transport protein IRK PF01007.20 GAX27634.1 - 0.14 12.0 5.9 1.3 8.9 0.9 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain MafB19-deam PF14437.6 GAX27635.1 - 5.3e-20 71.6 0.0 6.4e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 GAX27635.1 - 2.1e-17 62.8 0.2 5.7e-17 61.4 0.2 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 GAX27635.1 - 0.001 19.2 0.1 0.0019 18.3 0.1 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 GAX27635.1 - 0.0018 18.2 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 GAX27635.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 GAX27635.1 - 0.037 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 Bd3614-deam PF14439.6 GAX27635.1 - 0.085 12.9 0.8 0.15 12.1 0.7 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase NAD2 PF18782.1 GAX27635.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Na_Ca_ex PF01699.24 GAX27636.1 - 5.6e-36 123.8 40.4 1.8e-20 73.4 16.6 3.2 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF2678 PF10856.8 GAX27636.1 - 1.7e-05 24.7 0.3 5.8e-05 23.0 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF2569 PF10754.9 GAX27636.1 - 1.1 9.6 17.5 0.73 10.3 1.9 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2569) Methyltransf_22 PF13383.6 GAX27638.1 - 5.5e-89 298.1 0.4 6.4e-89 297.9 0.4 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 GAX27638.1 - 0.0036 17.4 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain Pro_isomerase PF00160.21 GAX27639.1 - 2.6e-49 167.5 0.1 3e-49 167.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TatD_DNase PF01026.21 GAX27640.1 - 3e-30 105.5 0.0 3.6e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CPBP PF02517.16 GAX27641.1 - 3.5e-13 49.7 3.6 9.6e-13 48.3 3.5 2.0 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease EF-hand_7 PF13499.6 GAX27641.1 - 0.024 15.1 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair His_Phos_1 PF00300.22 GAX27642.1 - 3.2e-16 59.6 0.0 5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MutS_V PF00488.21 GAX27643.1 - 2.2e-40 138.7 0.2 1.8e-29 103.1 0.0 2.6 3 0 0 3 3 3 2 MutS domain V MutS_III PF05192.18 GAX27643.1 - 3.8e-26 92.5 0.3 8e-26 91.4 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAX27643.1 - 0.0062 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV zf-HC2 PF13490.6 GAX27643.1 - 0.11 12.7 0.7 9 6.6 0.1 2.8 2 0 0 2 2 2 0 Putative zinc-finger ABC_tran PF00005.27 GAX27644.1 - 1.4e-31 109.9 2.0 2.4e-15 57.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAX27644.1 - 1.7e-12 47.7 2.4 0.00031 20.6 0.0 4.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX27644.1 - 7.3e-10 38.6 1.1 8.4e-09 35.2 1.1 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 GAX27644.1 - 1.9e-07 31.2 0.3 0.086 12.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 GAX27644.1 - 2.7e-07 31.3 17.1 0.0035 17.9 4.3 4.0 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 GAX27644.1 - 5.5e-07 29.7 0.0 0.0043 17.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 GAX27644.1 - 5.5e-07 30.1 0.5 0.095 13.1 0.0 3.9 4 1 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 GAX27644.1 - 6.5e-07 29.4 8.6 0.00012 21.9 8.6 3.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAX27644.1 - 8.7e-07 28.6 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 GAX27644.1 - 2.2e-06 27.5 0.0 1.5 8.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAX27644.1 - 2.8e-06 27.8 7.5 0.0071 16.7 3.7 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAX27644.1 - 3e-06 27.6 5.4 0.24 11.7 0.1 4.6 2 2 1 3 3 3 2 AAA domain TsaE PF02367.17 GAX27644.1 - 5.6e-05 23.1 0.1 0.042 13.9 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAX27644.1 - 7.9e-05 22.1 0.1 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX27644.1 - 0.0001 22.5 0.5 0.14 12.3 0.2 4.0 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 GAX27644.1 - 0.00029 21.1 0.8 0.25 11.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 GAX27644.1 - 0.00042 20.7 0.5 0.23 11.8 0.0 3.6 3 1 1 4 4 3 1 AAA domain RuvB_N PF05496.12 GAX27644.1 - 0.00042 20.1 0.2 0.055 13.2 0.0 3.6 3 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_13 PF13166.6 GAX27644.1 - 0.00059 18.6 12.1 0.98 8.0 0.0 3.9 3 1 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 GAX27644.1 - 0.0012 19.2 0.0 0.72 10.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 GAX27644.1 - 0.0013 18.3 0.0 0.32 10.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAX27644.1 - 0.0015 17.8 0.3 0.41 9.9 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_24 PF13479.6 GAX27644.1 - 0.0022 17.7 1.6 4.5 6.9 0.0 4.0 5 0 0 5 5 5 0 AAA domain T2SSE PF00437.20 GAX27644.1 - 0.0025 16.9 0.0 0.085 11.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.15 GAX27644.1 - 0.0039 17.1 2.0 2.3 8.1 0.1 4.3 5 0 0 5 5 4 1 NTPase PduV-EutP PF10662.9 GAX27644.1 - 0.0061 16.3 0.2 2.3 8.0 0.1 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 GAX27644.1 - 0.0075 16.2 0.0 2.9 7.8 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activat PF00158.26 GAX27644.1 - 0.0075 16.0 0.1 0.66 9.7 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain Roc PF08477.13 GAX27644.1 - 0.013 15.7 0.1 8.8 6.6 0.0 3.3 3 1 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 GAX27644.1 - 0.02 14.1 0.0 4.6 6.4 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.22 GAX27644.1 - 0.031 13.9 0.0 12 5.4 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 GAX27644.1 - 0.033 13.5 0.2 9.5 5.5 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family MobB PF03205.14 GAX27644.1 - 0.036 14.0 0.0 7.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.6 GAX27644.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAX27644.1 - 0.046 14.3 2.9 0.91 10.1 0.0 3.6 4 1 0 4 4 2 0 AAA domain IstB_IS21 PF01695.17 GAX27644.1 - 0.055 13.2 0.1 42 3.8 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein 7TMR-HDED PF07697.11 GAX27644.1 - 0.074 13.2 6.3 0.17 12.0 6.1 1.6 1 1 0 1 1 1 0 7TM-HD extracellular cobW PF02492.19 GAX27644.1 - 0.11 12.1 0.5 2 7.9 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 GAX27644.1 - 0.12 12.2 2.2 4 7.3 0.1 3.4 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TIR-like PF10137.9 GAX27644.1 - 0.14 12.1 0.1 0.57 10.1 0.0 2.1 2 0 0 2 2 1 0 Predicted nucleotide-binding protein containing TIR-like domain AAA_27 PF13514.6 GAX27644.1 - 0.2 11.2 5.9 0.22 11.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain Caps_synth_GfcC PF06251.11 GAX27644.1 - 0.47 10.0 3.1 0.74 9.4 2.2 1.8 1 1 0 1 1 1 0 Capsule biosynthesis GfcC AAA_11 PF13086.6 GAX27644.1 - 0.52 10.1 13.0 0.67 9.7 3.4 3.8 3 1 1 4 4 4 0 AAA domain Nmad5 PF18757.1 GAX27644.1 - 1 9.5 7.5 0.82 9.8 3.7 2.2 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 HlyD_2 PF12700.7 GAX27644.1 - 1.2 7.8 10.1 0.48 9.1 2.9 2.1 2 0 0 2 2 2 0 HlyD family secretion protein PIN_8 PF18476.1 GAX27644.1 - 2.3 8.0 11.9 1.1 9.1 5.8 2.3 2 0 0 2 2 2 0 PIN like domain DUF3584 PF12128.8 GAX27644.1 - 4.1 4.8 29.8 1.6 6.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) YtxH PF12732.7 GAX27644.1 - 8.3 7.0 9.7 2.7 8.6 5.1 2.5 2 1 0 2 2 1 0 YtxH-like protein DUF3387 PF11867.8 GAX27646.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Xan_ur_permease PF00860.20 GAX27647.1 - 3.3e-63 213.7 26.7 1.1e-42 146.1 11.8 2.1 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 GAX27647.1 - 0.00073 18.4 6.3 0.00073 18.4 6.3 1.9 2 1 0 2 2 2 1 Sulfate permease family dCMP_cyt_deam_1 PF00383.23 GAX27648.1 - 9.4e-09 35.1 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX27648.1 - 4.2e-05 23.3 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAX27648.1 - 0.072 13.2 0.2 0.12 12.5 0.2 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase Bap31_Bap29_C PF18035.1 GAX27648.1 - 0.19 11.8 3.0 0.38 10.8 3.0 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain UpxZ PF06603.11 GAX27649.1 - 0.082 13.2 0.3 1.2 9.5 0.2 2.5 1 1 1 2 2 2 0 UpxZ family of transcription anti-terminator antagonists DUF434 PF04256.12 GAX27649.1 - 0.095 12.4 0.0 0.32 10.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Fe_hyd_SSU PF02256.17 GAX27649.1 - 0.15 12.2 0.5 0.46 10.6 0.5 1.8 1 0 0 1 1 1 0 Iron hydrogenase small subunit PTS_IIA PF02255.16 GAX27649.1 - 1.1 9.4 7.3 1.4 9.0 0.2 2.5 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Abhydrolase_1 PF00561.20 GAX27650.1 - 4.8e-10 39.5 0.0 6.8e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX27650.1 - 7.9e-08 33.2 1.8 8.1e-07 29.9 1.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX27650.1 - 0.00043 19.6 0.1 0.25 10.6 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAX27650.1 - 0.0049 17.0 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.12 GAX27650.1 - 0.018 14.1 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 GAX27650.1 - 0.019 15.1 0.0 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein Peptidase_S9 PF00326.21 GAX27650.1 - 0.026 14.0 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 GAX27650.1 - 0.097 12.2 0.0 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 GAX27650.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 GAX27650.1 - 0.12 12.1 0.0 0.65 9.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAX27650.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 GAX27650.1 - 0.18 11.4 0.0 2.6 7.5 0.0 2.0 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 GAX27650.1 - 0.21 11.2 0.0 0.41 10.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Cyt-b5 PF00173.28 GAX27651.1 - 3.1e-20 72.1 0.1 5.3e-20 71.3 0.1 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4366 PF14283.6 GAX27651.1 - 0.058 13.4 0.4 0.06 13.4 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) CD34_antigen PF06365.12 GAX27651.1 - 0.067 12.8 0.0 0.3 10.6 0.0 1.8 1 1 1 2 2 2 0 CD34/Podocalyxin family SNARE PF05739.19 GAX27651.1 - 0.15 12.0 0.2 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 SNARE domain Amnionless PF14828.6 GAX27651.1 - 0.16 10.8 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Amnionless Cornifin PF02389.15 GAX27654.1 - 0.0022 18.2 3.3 0.0093 16.2 3.3 2.1 1 1 0 1 1 1 1 Cornifin (SPRR) family eIF3_subunit PF08597.10 GAX27654.1 - 1.9 8.3 27.2 0.11 12.4 17.6 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit RR_TM4-6 PF06459.12 GAX27654.1 - 2.7 7.7 12.8 0.2 11.4 6.3 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 GAX27654.1 - 4.6 7.7 14.6 4.3 7.7 8.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 GAX27654.1 - 9.2 6.4 10.0 0.67 10.1 4.0 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Beta_elim_lyase PF01212.21 GAX27655.1 - 5.4e-30 104.7 0.0 6.6e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase AbfB PF05270.13 GAX27655.1 - 0.025 14.6 0.2 0.31 11.0 0.0 2.5 2 1 1 3 3 3 0 Alpha-L-arabinofuranosidase B (ABFB) domain UDPGP PF01704.18 GAX27656.1 - 9.5e-19 67.3 0.0 1.7e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ala_racemase_N PF01168.20 GAX27657.1 - 4.8e-24 85.2 0.0 6e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Inj_translocase PF16928.5 GAX27657.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome RPN13_C PF16550.5 GAX27658.1 - 6.6e-21 74.6 1.1 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 UCH-binding domain Proteasom_Rpn13 PF04683.13 GAX27658.1 - 9.8e-07 29.2 0.8 1.8e-06 28.4 0.8 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CDC45 PF02724.14 GAX27658.1 - 7 4.8 9.6 0.16 10.2 2.6 1.7 2 0 0 2 2 2 0 CDC45-like protein SET PF00856.28 GAX27660.1 - 1.4e-06 28.8 0.0 0.002 18.5 0.0 3.5 2 1 0 2 2 2 1 SET domain Cyclin_N PF00134.23 GAX27661.1 - 4.5e-11 42.6 0.1 7.1e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX27661.1 - 0.0046 17.0 1.9 0.0071 16.4 0.3 2.0 1 1 1 2 2 2 1 Cyclin, C-terminal domain Nse4_C PF08743.10 GAX27663.1 - 1.4e-15 57.3 0.0 6.1e-15 55.2 0.0 2.2 1 0 0 1 1 1 1 Nse4 C-terminal Cyclin_N PF00134.23 GAX27665.1 - 4.1e-11 42.7 0.2 6.1e-10 38.9 0.2 2.2 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX27665.1 - 0.0011 19.1 0.2 0.0024 18.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain AhpC-TSA_2 PF13911.6 GAX27666.1 - 2.6e-11 43.6 0.0 4.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 GAX27666.1 - 0.00069 19.3 0.0 0.0024 17.6 0.0 1.8 1 1 1 2 2 2 1 Redoxin NAD_binding_1 PF00175.21 GAX27666.1 - 0.022 15.4 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain HEAT PF02985.22 GAX27667.1 - 4.8e-19 66.8 27.8 2.8e-05 24.0 0.2 11.7 13 0 0 13 13 12 6 HEAT repeat HEAT_EZ PF13513.6 GAX27667.1 - 1.3e-16 60.7 41.8 4.6e-05 23.8 0.9 12.9 11 2 2 13 13 13 7 HEAT-like repeat HEAT_2 PF13646.6 GAX27667.1 - 7.4e-15 55.1 18.9 0.00077 19.8 0.1 10.2 5 3 7 12 12 12 5 HEAT repeats Vac14_Fab1_bd PF12755.7 GAX27667.1 - 7.7e-12 45.7 0.1 0.00053 20.5 0.0 6.4 6 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region UME PF08064.13 GAX27667.1 - 8.4e-10 38.5 0.1 0.88 9.5 0.0 7.5 6 2 1 7 7 7 2 UME (NUC010) domain CLASP_N PF12348.8 GAX27667.1 - 1.2e-08 34.8 0.1 0.11 12.0 0.0 5.8 5 0 0 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 GAX27667.1 - 1.4e-08 34.9 0.0 0.001 19.1 0.0 4.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 GAX27667.1 - 7e-06 25.9 0.0 1 9.1 0.0 4.4 4 0 0 4 4 4 2 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 GAX27667.1 - 6.7e-05 22.6 0.0 0.11 12.1 0.0 4.3 5 1 1 6 6 6 1 Tti2 family Adaptin_N PF01602.20 GAX27667.1 - 0.00014 20.6 0.0 0.012 14.2 0.0 3.1 3 0 0 3 3 3 1 Adaptin N terminal region IBN_N PF03810.19 GAX27667.1 - 0.00069 19.5 0.7 0.0073 16.2 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Importin_rep_4 PF18808.1 GAX27667.1 - 0.0011 19.2 6.1 0.0027 18.0 0.1 3.5 3 0 0 3 3 2 1 Importin repeat RTP1_C1 PF10363.9 GAX27667.1 - 0.033 14.4 0.0 6.7 6.9 0.0 3.9 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-MYND PF01753.18 GAX27668.1 - 9.5e-06 25.6 18.6 1.7e-05 24.8 18.6 1.4 1 0 0 1 1 1 1 MYND finger THF_DHG_CYH_C PF02882.19 GAX27670.1 - 9.1e-63 210.4 0.9 1.3e-62 209.8 0.4 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAX27670.1 - 3.5e-40 136.9 0.2 5.5e-40 136.3 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 GAX27670.1 - 0.0025 16.8 0.1 0.004 16.1 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AlaDh_PNT_C PF01262.21 GAX27670.1 - 0.023 14.0 2.9 0.086 12.1 3.0 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 GAX27670.1 - 0.047 14.1 0.2 0.12 12.8 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding PAP_fibrillin PF04755.12 GAX27672.1 - 2.5e-07 30.9 0.0 4e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 PAP_fibrillin Myosin_head PF00063.21 GAX27673.1 - 1.4e-205 684.5 0.2 3.2e-205 683.3 0.2 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 GAX27673.1 - 0.00074 19.9 0.0 0.0032 17.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 GAX27673.1 - 0.0014 17.8 0.1 0.0025 16.9 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 GAX27673.1 - 0.0015 18.8 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF3987 PF13148.6 GAX27673.1 - 0.011 14.7 0.3 0.021 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_10 PF12846.7 GAX27673.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.26 GAX27673.1 - 0.038 13.7 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 GAX27673.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_S19 PF00203.21 GAX27674.1 - 6.9e-31 106.0 0.1 9.3e-31 105.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 GAX27674.1 - 0.0031 17.6 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH DEAD PF00270.29 GAX27675.1 - 3.5e-41 140.9 0.0 1e-40 139.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX27675.1 - 4.4e-27 94.6 0.0 5.3e-26 91.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 GAX27675.1 - 1.2e-10 41.4 5.5 1.2e-10 41.4 5.5 2.7 2 0 0 2 2 2 1 DBP10CT (NUC160) domain AAA_22 PF13401.6 GAX27675.1 - 0.1 12.9 0.1 0.89 9.8 0.0 2.6 3 1 0 3 3 3 0 AAA domain Ribosomal_S9 PF00380.19 GAX27675.1 - 0.55 10.8 7.6 1.8 9.1 7.6 1.9 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Cupin_8 PF13621.6 GAX27676.1 - 1.2e-13 51.3 0.0 6.4e-13 49.0 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain Chromo PF00385.24 GAX27676.1 - 1.2e-06 28.3 3.1 0.01 15.7 0.2 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain JmjC PF02373.22 GAX27676.1 - 0.0004 20.8 0.0 0.0048 17.3 0.0 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase DEK_C PF08766.11 GAX27677.1 - 0.019 14.9 0.4 0.056 13.4 0.2 2.0 2 0 0 2 2 2 0 DEK C terminal domain tRNA_int_end_N2 PF12928.7 GAX27678.1 - 0.043 14.0 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term ECH_2 PF16113.5 GAX27679.1 - 4.3e-23 82.4 0.0 4.4e-12 46.1 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAX27679.1 - 0.001 18.4 0.0 0.0098 15.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase HOOK PF05622.12 GAX27680.1 - 2.2e-44 151.8 61.3 2.1e-40 138.6 52.7 2.9 1 1 1 2 2 2 2 HOOK protein CdvA PF18822.1 GAX27680.1 - 0.0013 18.6 9.4 0.0013 18.6 9.4 5.3 4 2 1 5 5 5 2 CdvA-like coiled-coil domain BLOC1_2 PF10046.9 GAX27680.1 - 0.016 15.5 7.2 0.016 15.5 7.2 6.3 2 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.6 GAX27680.1 - 0.017 15.1 10.7 0.017 15.1 10.7 5.7 4 2 2 6 6 6 0 FlxA-like protein MAD PF05557.13 GAX27680.1 - 0.49 8.7 65.9 0.058 11.8 37.1 2.2 2 0 0 2 2 2 0 Mitotic checkpoint protein Atg14 PF10186.9 GAX27680.1 - 0.93 8.5 62.4 0.14 11.2 18.2 3.4 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 GAX27680.1 - 1.2 8.8 63.3 0.06 13.1 25.5 4.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 GAX27680.1 - 1.7 9.1 87.8 1.7 9.2 10.1 4.7 2 1 3 5 5 4 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 GAX27680.1 - 2 7.8 65.5 0.46 9.9 13.6 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 FUSC PF04632.12 GAX27680.1 - 2.9 6.3 28.2 1.8 7.0 16.2 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 GAX27680.1 - 3.3 7.7 81.1 0.23 11.5 16.8 5.1 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 GAX27680.1 - 3.7 6.9 75.7 1 8.8 41.5 3.7 2 2 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Baculo_PEP_C PF04513.12 GAX27680.1 - 4 7.5 29.8 0.1 12.6 4.5 4.1 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 GAX27680.1 - 4.2 7.2 7.2 15 5.4 0.3 4.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 Peptidase_C10 PF01640.17 GAX27680.1 - 4.4 7.6 8.2 4.5 7.5 1.0 2.9 3 0 0 3 3 3 0 Peptidase C10 family TMF_TATA_bd PF12325.8 GAX27680.1 - 8.2 6.7 72.2 1.6 9.0 3.5 5.8 2 2 4 6 6 6 0 TATA element modulatory factor 1 TATA binding ATP-synt_C PF00137.21 GAX27681.1 - 1.2e-28 99.3 28.5 3.5e-15 56.1 9.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 GAX27681.1 - 0.16 11.3 1.6 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Thioredoxin_8 PF13905.6 GAX27682.1 - 0.00068 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 GAX27682.1 - 0.0045 17.0 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF2688 PF10892.8 GAX27682.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Cwf_Cwc_15 PF04889.12 GAX27683.1 - 0.015 15.1 3.7 0.027 14.2 3.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein cIII PF08134.11 GAX27684.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 cIII protein family RRM_1 PF00076.22 GAX27685.1 - 2.3e-39 133.1 0.0 2.9e-19 68.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 GAX27685.1 - 0.00016 21.6 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_7 PF16367.5 GAX27685.1 - 0.0076 16.4 0.0 5 7.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif GDP_Man_Dehyd PF16363.5 GAX27686.1 - 3.1e-62 210.9 0.0 8.4e-62 209.5 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAX27686.1 - 2.8e-56 190.7 0.0 4e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX27686.1 - 2.5e-18 66.1 0.0 3.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAX27686.1 - 1.7e-17 63.5 0.0 1.9e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAX27686.1 - 1.5e-13 50.5 0.0 2.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAX27686.1 - 3.8e-12 45.9 0.0 6.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 GAX27686.1 - 3.5e-05 23.3 0.1 0.0012 18.3 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAX27686.1 - 6.5e-05 22.9 0.2 0.00058 19.8 0.2 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAX27686.1 - 8.6e-05 22.5 0.0 0.00036 20.5 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox PF00070.27 GAX27686.1 - 0.01 16.4 0.0 0.034 14.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 GAX27686.1 - 0.019 15.3 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 GAX27686.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAX27686.1 - 0.031 14.5 0.0 0.091 13.0 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 GAX27686.1 - 0.092 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 GAX27686.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DAO PF01266.24 GAX27686.1 - 0.18 11.4 0.1 0.41 10.2 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase PPR_2 PF13041.6 GAX27688.1 - 3.2e-47 158.5 6.1 9.3e-14 51.4 0.0 9.7 7 3 2 10 10 10 6 PPR repeat family PPR_1 PF12854.7 GAX27688.1 - 2.3e-35 120.0 2.5 0.0001 21.9 0.0 10.2 10 0 0 10 10 10 6 PPR repeat PPR PF01535.20 GAX27688.1 - 1.7e-34 115.6 7.2 4e-05 23.6 0.0 10.7 10 1 0 10 10 9 7 PPR repeat PPR_3 PF13812.6 GAX27688.1 - 1.1e-29 102.3 1.5 1.2e-05 25.3 0.0 8.8 8 1 1 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX27688.1 - 2.3e-10 40.2 1.9 0.00031 20.2 0.6 5.1 2 1 3 5 5 5 2 Pentacotripeptide-repeat region of PRORP EamA PF00892.20 GAX27688.1 - 1e-05 25.7 26.8 0.00025 21.2 11.7 2.7 2 0 0 2 2 2 2 EamA-like transporter family TPR_19 PF14559.6 GAX27688.1 - 0.00014 22.3 2.4 6.8 7.3 0.1 4.7 3 1 2 5 5 5 1 Tetratricopeptide repeat TPT PF03151.16 GAX27688.1 - 0.00053 19.4 6.3 0.0022 17.4 6.1 1.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 GAX27688.1 - 0.0011 18.3 3.7 0.0012 18.1 2.3 1.8 2 1 0 2 2 2 1 Nucleotide-sugar transporter ATP13 PF12921.7 GAX27688.1 - 0.0016 18.3 0.0 9.7 6.1 0.0 4.5 3 1 0 3 3 3 1 Mitochondrial ATPase expression UAA PF08449.11 GAX27688.1 - 0.0038 16.5 4.4 0.0038 16.5 4.4 1.7 2 0 0 2 2 2 1 UAA transporter family MRP-S27 PF10037.9 GAX27688.1 - 0.012 14.5 0.2 0.66 8.8 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 GAX27688.1 - 0.034 15.0 0.5 1.7e+02 3.4 0.2 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Histone PF00125.24 GAX27689.1 - 6.9e-54 181.7 1.0 7.7e-54 181.6 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GAX27689.1 - 0.00011 22.7 1.1 0.00014 22.5 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GAX27689.1 - 0.00072 19.6 0.3 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX27689.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAX27689.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAX27689.1 - 0.045 13.8 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 GAX27690.1 - 2.8e-19 69.8 0.4 3.6e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX27690.1 - 0.00095 19.4 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAX27690.1 - 0.0039 17.6 0.0 0.0068 16.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 GAX27690.1 - 0.0062 16.6 0.1 0.0069 16.4 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein Bt_P21 PF05560.11 GAX27690.1 - 0.046 13.3 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein BCIP PF13862.6 GAX27691.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 2 0 0 2 2 2 0 p21-C-terminal region-binding protein CENP-T_C PF15511.6 GAX27692.1 - 9.6e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAX27692.1 - 0.00017 21.9 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 GAX27692.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 GAX27692.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX27692.1 - 0.0047 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GAX27692.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAX27692.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 GAX27692.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) SET PF00856.28 GAX27693.1 - 7.7e-15 55.7 0.0 4.4e-07 30.4 0.0 4.2 2 2 1 3 3 3 2 SET domain SAF PF08666.12 GAX27693.1 - 0.012 16.2 0.0 11 6.7 0.0 3.5 3 0 0 3 3 3 0 SAF domain TLC PF03219.14 GAX27694.1 - 1.4e-138 462.7 15.0 1.9e-138 462.3 15.0 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF4492 PF14899.6 GAX27694.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) OST3_OST6 PF04756.13 GAX27694.1 - 1 8.7 10.1 0.64 9.3 1.0 2.9 3 1 1 4 4 4 0 OST3 / OST6 family, transporter family CBM9_1 PF06452.11 GAX27695.1 - 4.9e-05 23.3 0.2 8e-05 22.6 0.2 1.5 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like Attacin_N PF03768.15 GAX27695.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Attacin, N-terminal region DUF285 PF03382.14 GAX27696.1 - 4.7e-58 194.2 27.8 1.3e-31 108.9 7.2 2.3 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 ATG11 PF10377.9 GAX27696.1 - 0.034 14.2 2.3 1.7 8.7 0.2 2.3 1 1 1 2 2 2 0 Autophagy-related protein 11 ProRS-C_1 PF09180.11 GAX27697.1 - 6.2e-22 77.6 0.3 1.4e-21 76.5 0.3 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 GAX27697.1 - 8.3e-20 71.5 0.0 2.1e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAX27697.1 - 1.1e-18 67.2 0.0 4.2e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.15 GAX27697.1 - 4.3e-17 62.3 0.5 4.7e-16 59.0 0.3 2.6 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain baeRF_family11 PF18855.1 GAX27697.1 - 0.039 14.3 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 baeRF_family12 PF18856.1 GAX27697.1 - 0.12 13.0 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Ribosomal_S21e PF01249.18 GAX27698.1 - 7.9e-35 118.8 0.1 9.4e-35 118.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e DnaJ PF00226.31 GAX27701.1 - 3.9e-18 65.3 1.9 3.9e-18 65.3 1.9 1.9 2 0 0 2 2 2 1 DnaJ domain DUF3858 PF12970.7 GAX27701.1 - 0.023 14.7 0.9 0.047 13.7 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) Sec62 PF03839.16 GAX27701.1 - 0.06 12.8 0.3 0.06 12.8 0.3 2.7 4 0 0 4 4 4 0 Translocation protein Sec62 Conotoxin PF02950.17 GAX27701.1 - 0.19 12.8 0.5 2.5 9.2 0.0 3.0 3 0 0 3 3 3 0 Conotoxin DUF2157 PF09925.9 GAX27701.1 - 0.28 11.0 3.5 8 6.2 0.2 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) BolA PF01722.18 GAX27702.1 - 3.5e-17 62.4 0.0 4.4e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Pox_L3_FP4 PF03339.14 GAX27702.1 - 0.18 10.8 0.0 0.19 10.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein Peptidase_M6 PF05547.11 GAX27704.1 - 2.5e-07 29.5 4.3 6.7e-06 24.7 4.3 2.4 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 Peptidase_M6 PF05547.11 GAX27705.1 - 2.6e-12 45.9 6.4 2.6e-12 45.9 6.4 2.5 2 1 0 2 2 2 1 Immune inhibitor A peptidase M6 Asp_protease PF09668.10 GAX27706.1 - 1.5e-41 141.1 1.6 1.5e-41 141.1 0.4 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GAX27706.1 - 1.6e-14 54.2 0.0 3.1e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAX27706.1 - 4.8e-08 33.5 0.0 8.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GAX27706.1 - 0.0084 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease SUI1 PF01253.22 GAX27707.1 - 1.4e-14 54.4 1.1 2.4e-14 53.6 1.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 YL1 PF05764.13 GAX27707.1 - 0.0076 16.4 2.9 0.011 15.9 2.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF1726 PF08351.11 GAX27707.1 - 0.03 14.2 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) eIF-3c_N PF05470.12 GAX27707.1 - 0.21 9.9 2.4 0.26 9.6 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PBP1_TM PF14812.6 GAX27707.1 - 0.21 12.0 4.3 0.4 11.1 4.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 GAX27707.1 - 0.22 9.8 1.1 0.25 9.6 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein MatE PF01554.18 GAX27708.1 - 3.6e-22 78.7 31.7 2.9e-17 62.8 10.1 2.6 3 0 0 3 3 3 2 MatE MurJ PF03023.14 GAX27708.1 - 1.1e-13 50.6 6.7 1.1e-13 50.6 6.7 2.5 2 1 1 3 3 3 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 GAX27708.1 - 2.6e-12 47.0 1.7 2.6e-12 47.0 1.7 4.0 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Fer4_13 PF13370.6 GAX27709.1 - 1.1e-15 57.9 3.0 3.6e-15 56.2 3.0 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 GAX27709.1 - 2.7e-07 31.2 2.5 1.3e-06 29.0 2.5 2.3 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 GAX27709.1 - 0.0018 18.3 1.6 0.0018 18.3 1.6 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Pox_Rap94 PF03294.14 GAX27709.1 - 0.078 11.1 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 Fer4_NifH PF00142.18 GAX27709.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Fer4_10 PF13237.6 GAX27709.1 - 2.4 8.3 11.6 2.4 8.3 2.9 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain SRPRB PF09439.10 GAX27711.1 - 2.6e-21 75.9 0.0 3.5e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 GAX27711.1 - 1.4e-06 27.9 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAX27711.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAX27711.1 - 0.00085 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAX27711.1 - 0.0047 17.3 0.1 1 9.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain Transketolase_C PF02780.20 GAX27711.1 - 0.0057 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain AAA_14 PF13173.6 GAX27711.1 - 0.0095 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX27711.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein FeoB_N PF02421.18 GAX27711.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B CS PF04969.16 GAX27712.1 - 0.0065 17.5 0.3 0.015 16.3 0.3 1.6 1 0 0 1 1 1 1 CS domain TPT PF03151.16 GAX27713.1 - 1.3e-27 97.0 4.6 3.7e-27 95.4 4.6 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX27713.1 - 8.9e-11 42.1 22.6 1.8e-06 28.1 8.2 3.1 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAX27713.1 - 0.019 14.2 9.8 0.048 12.9 9.7 1.6 1 1 0 1 1 1 0 UAA transporter family Thioredoxin PF00085.20 GAX27714.1 - 3.4e-21 75.2 0.2 8.9e-21 73.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX27714.1 - 0.00028 21.3 0.5 0.00095 19.6 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAX27714.1 - 0.00032 20.8 0.9 0.0048 17.1 0.1 2.6 3 0 0 3 3 3 1 Thioredoxin-like Spectrin PF00435.21 GAX27714.1 - 0.0019 18.6 4.8 0.0037 17.7 4.8 1.5 1 0 0 1 1 1 1 Spectrin repeat Redoxin PF08534.10 GAX27714.1 - 0.0065 16.2 1.1 0.01 15.6 0.0 1.9 3 0 0 3 3 3 1 Redoxin AhpC-TSA PF00578.21 GAX27714.1 - 0.0067 16.3 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 GAX27714.1 - 0.0069 16.7 0.1 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.6 GAX27714.1 - 0.52 10.4 5.0 2.6 8.2 4.8 2.2 1 1 0 1 1 1 0 Thioredoxin UPRTase PF14681.6 GAX27715.1 - 4.8e-61 205.8 0.2 5.7e-61 205.6 0.2 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAX27715.1 - 0.049 13.1 0.1 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase domain PqiA PF04403.13 GAX27715.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Paraquat-inducible protein A Thioredoxin PF00085.20 GAX27716.1 - 3.2e-11 43.1 0.0 4.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX27716.1 - 0.0003 21.1 0.0 0.00064 20.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 GAX27716.1 - 0.054 12.8 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DIM1 PF02966.16 GAX27716.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 GAX27716.1 - 0.13 12.5 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like TENA_THI-4 PF03070.16 GAX27717.1 - 1.9e-18 67.0 0.1 2.2e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF720 PF05302.11 GAX27718.1 - 0.51 10.2 5.8 2.8 7.8 5.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF720) Aa_trans PF01490.18 GAX27719.1 - 1.7e-55 188.4 15.1 1.7e-55 188.4 15.1 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein FAM70 PF14967.6 GAX27719.1 - 0.02 14.4 0.3 0.037 13.5 0.3 1.4 1 0 0 1 1 1 0 FAM70 protein TrmB PF01978.19 GAX27720.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ABC_tran PF00005.27 GAX27721.1 - 8.1e-28 97.6 2.3 2e-15 57.5 0.2 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAX27721.1 - 1.1e-11 45.1 4.6 6.4e-06 26.2 0.3 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX27721.1 - 2.5e-08 34.5 4.0 6.5e-06 26.6 0.6 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAX27721.1 - 1.6e-06 28.4 3.1 0.0077 16.5 0.1 3.1 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.19 GAX27721.1 - 9.8e-06 25.2 1.7 0.37 10.2 0.0 3.4 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX27721.1 - 4.1e-05 23.2 0.3 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 GAX27721.1 - 0.00016 21.9 2.6 0.29 11.3 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX27721.1 - 0.00023 21.7 0.5 0.095 13.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 GAX27721.1 - 0.00042 20.5 0.2 0.64 10.3 0.1 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 GAX27721.1 - 0.00045 19.9 0.2 0.42 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.6 GAX27721.1 - 0.00067 18.4 0.1 0.0091 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAX27721.1 - 0.00083 19.3 0.3 0.56 10.1 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 GAX27721.1 - 0.00097 19.2 0.3 0.89 9.7 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 GAX27721.1 - 0.0014 18.2 0.7 0.37 10.3 0.6 3.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX27721.1 - 0.0064 15.8 0.0 0.19 11.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 GAX27721.1 - 0.0088 16.3 0.3 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAX27721.1 - 0.031 13.4 0.1 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 GAX27721.1 - 0.036 14.6 0.0 10 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAX27721.1 - 0.037 13.8 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 GAX27721.1 - 0.043 13.8 0.1 6.2 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAX27721.1 - 0.048 12.8 0.1 1.8 7.7 0.0 2.4 2 1 0 2 2 2 0 NB-ARC domain Ploopntkinase1 PF18748.1 GAX27721.1 - 0.062 12.8 0.0 0.2 11.1 0.0 1.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase1 Arf PF00025.21 GAX27721.1 - 0.076 12.5 0.2 0.93 8.9 0.0 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.19 GAX27721.1 - 0.089 12.4 0.3 6.8 6.2 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAX27721.1 - 0.092 12.5 2.0 5.5 6.7 0.1 2.8 3 1 0 3 3 2 0 AAA domain AAA_14 PF13173.6 GAX27721.1 - 0.095 12.7 0.1 25 4.9 0.0 2.9 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 GAX27721.1 - 0.098 13.0 0.0 19 5.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 GAX27721.1 - 0.1 12.5 7.4 0.56 10.1 1.2 3.3 2 2 0 2 2 2 0 NACHT domain Flavin_Reduct PF01613.18 GAX27722.1 - 2.4e-10 40.7 0.0 5.4e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Flavin reductase like domain IHABP4_N PF16174.5 GAX27723.1 - 2.1 8.9 10.4 4.2 8.0 10.4 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DnaJ_C PF01556.18 GAX27724.1 - 4e-21 75.6 0.0 5.7e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX27724.1 - 2.1e-18 66.2 0.1 3.8e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Patched PF02460.18 GAX27725.1 - 6e-35 120.6 35.0 6.9e-18 64.1 7.2 3.1 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 GAX27725.1 - 1.8e-20 73.4 6.8 1.8e-20 73.4 6.8 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Acetyltransf_1 PF00583.25 GAX27726.1 - 7.2e-14 52.0 0.0 1e-13 51.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX27726.1 - 4.9e-10 39.7 0.0 7.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX27726.1 - 8.3e-09 35.5 0.0 2.8e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX27726.1 - 0.0011 18.9 0.0 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 GAX27726.1 - 0.0055 17.4 0.0 0.011 16.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX27726.1 - 0.021 14.9 0.0 0.098 12.8 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 GAX27726.1 - 0.044 13.9 0.0 0.061 13.5 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAX27726.1 - 0.07 12.9 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Pkinase PF00069.25 GAX27728.1 - 1.5e-05 24.5 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAX27728.1 - 0.0014 17.5 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase GHMP_kinases_C PF08544.13 GAX27728.1 - 0.087 13.2 0.1 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 GHMP kinases C terminal CTF_NFI PF00859.18 GAX27733.1 - 0.069 13.0 0.6 0.16 11.8 0.2 1.5 1 1 1 2 2 2 0 CTF/NF-I family transcription modulation region SAYSvFN PF10260.9 GAX27735.1 - 7.7e-13 48.2 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) DUF4386 PF14329.6 GAX27736.1 - 0.00081 19.3 1.5 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4386) DUF4131 PF13567.6 GAX27736.1 - 0.0061 16.2 0.1 0.0061 16.2 0.1 2.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4131) AI-2E_transport PF01594.16 GAX27736.1 - 0.011 14.9 1.4 0.011 14.9 1.4 1.9 1 1 1 2 2 2 0 AI-2E family transporter DUF4079 PF13301.6 GAX27736.1 - 0.012 15.7 0.8 0.027 14.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2721 PF11026.8 GAX27736.1 - 0.015 15.2 3.7 0.015 15.2 3.7 3.0 2 1 0 2 2 1 0 Protein of unknown function (DUF2721) UbiA PF01040.18 GAX27736.1 - 0.03 13.6 0.2 0.03 13.6 0.2 1.9 2 0 0 2 2 2 0 UbiA prenyltransferase family DUF3290 PF11694.8 GAX27736.1 - 0.031 14.3 0.2 0.031 14.3 0.2 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3290) bZIP_1 PF00170.21 GAX27736.1 - 0.062 13.4 6.5 0.15 12.2 6.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor Wzz PF02706.15 GAX27736.1 - 0.094 13.0 0.8 0.52 10.7 0.1 2.5 2 1 1 3 3 3 0 Chain length determinant protein UPF0242 PF06785.11 GAX27736.1 - 0.31 11.1 13.2 4 7.5 8.3 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF2142 PF09913.9 GAX27736.1 - 0.63 8.8 5.8 1.4 7.7 5.3 1.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2142) CDC45 PF02724.14 GAX27736.1 - 0.7 8.1 8.1 0.13 10.5 3.5 1.8 2 0 0 2 2 2 0 CDC45-like protein TauE PF01925.19 GAX27736.1 - 0.99 9.0 9.0 0.074 12.7 3.7 1.7 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DUF1772 PF08592.11 GAX27736.1 - 1.3 9.3 7.1 11 6.3 4.5 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF2236 PF09995.9 GAX27737.1 - 6.8e-24 85.3 0.1 1.1e-23 84.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DALR_1 PF05746.15 GAX27738.1 - 0.012 15.7 0.2 0.035 14.3 0.1 1.8 1 1 1 2 2 2 0 DALR anticodon binding domain ABC1 PF03109.16 GAX27739.1 - 2.7e-23 82.4 0.0 6.7e-23 81.1 0.0 1.7 1 1 0 1 1 1 1 ABC1 family APH PF01636.23 GAX27739.1 - 2.5e-05 24.3 0.9 0.00023 21.1 0.8 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Agenet PF05641.12 GAX27740.1 - 2.4 8.7 7.0 19 5.8 0.0 3.9 4 0 0 4 4 4 0 Agenet domain SnoaL_2 PF12680.7 GAX27741.1 - 2e-06 28.4 0.0 3.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 GAX27741.1 - 0.036 14.6 0.2 0.071 13.7 0.2 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SnoaL PF07366.12 GAX27741.1 - 0.046 13.5 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF2834 PF11196.8 GAX27741.1 - 0.44 10.9 2.8 0.86 10.0 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) PIG-S PF10510.9 GAX27742.1 - 7e-05 21.8 0.3 0.0003 19.8 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein H2O2_YaaD PF03883.14 GAX27744.1 - 1.9e-64 217.4 0.0 2.3e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Peroxide stress protein YaaA DUF413 PF04219.12 GAX27745.1 - 0.058 13.4 1.3 0.092 12.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF TruD PF01142.18 GAX27746.1 - 7e-65 219.5 0.0 2.8e-64 217.5 0.0 1.9 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) RPOL_N PF14700.6 GAX27746.1 - 0.13 11.6 0.3 1.1 8.6 0.0 2.3 3 0 0 3 3 3 0 DNA-directed RNA polymerase N-terminal Arf PF00025.21 GAX27747.1 - 5.7e-67 224.5 0.1 6.4e-67 224.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAX27747.1 - 6.2e-13 49.0 0.0 8.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAX27747.1 - 1.9e-12 47.0 0.0 2.3e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAX27747.1 - 6.7e-12 45.3 0.0 7.9e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAX27747.1 - 4.9e-10 39.1 1.3 2.7e-05 23.5 0.1 2.4 2 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 GAX27747.1 - 9.9e-09 35.3 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAX27747.1 - 5.7e-06 25.9 0.0 6.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAX27747.1 - 0.00069 19.2 0.0 0.034 13.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAX27747.1 - 0.018 14.1 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 GAX27747.1 - 0.043 13.4 0.0 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAX27747.1 - 0.11 12.4 0.2 0.21 11.5 0.2 1.5 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 GAX27747.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea F-box PF00646.33 GAX27748.1 - 0.00038 20.3 0.0 0.0013 18.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAX27748.1 - 0.00055 19.8 0.0 0.002 18.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like DUF3301 PF11743.8 GAX27749.1 - 0.085 12.5 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Stb3 PF10330.9 GAX27749.1 - 0.18 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative Sin3 binding protein Herpes_UL52 PF03121.15 GAX27750.1 - 2e-08 34.1 0.3 3.6e-08 33.2 0.3 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase DUF3631 PF12307.8 GAX27750.1 - 0.029 14.6 1.1 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) Acetyltransf_1 PF00583.25 GAX27751.1 - 1.9e-10 41.0 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX27751.1 - 2.8e-06 27.3 0.0 6.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX27751.1 - 5e-05 23.6 0.0 0.00011 22.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX27751.1 - 0.00028 20.8 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF5345 PF17280.2 GAX27751.1 - 0.79 9.7 2.5 1.5 8.8 0.4 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5345) Metallophos PF00149.28 GAX27752.1 - 1.3e-37 130.4 0.3 1.8e-37 129.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAX27752.1 - 9.7e-15 54.8 0.3 2e-14 53.7 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain EamA PF00892.20 GAX27753.1 - 2e-11 44.2 31.0 4.3e-05 23.7 9.6 3.2 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 GAX27753.1 - 0.006 15.8 0.7 0.006 15.8 0.7 2.4 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 GAX27753.1 - 0.017 14.9 4.0 0.11 12.3 4.0 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) Mt_ATP-synt_D PF05873.12 GAX27754.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF2193 PF09959.9 GAX27755.1 - 0.089 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) NAD_binding_10 PF13460.6 GAX27756.1 - 2e-25 89.8 0.0 2.5e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAX27756.1 - 2e-08 34.0 0.0 4.9e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAX27756.1 - 2.7e-06 27.1 0.0 4.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 GAX27756.1 - 8.4e-05 23.0 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GAX27756.1 - 8.4e-05 21.9 0.0 0.0013 18.0 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 GAX27756.1 - 0.00019 20.7 0.0 0.00057 19.1 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAX27756.1 - 0.00026 20.5 0.0 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 GAX27756.1 - 0.00067 19.9 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAX27756.1 - 0.00086 19.4 0.0 0.0029 17.7 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAX27756.1 - 0.0036 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 GAX27756.1 - 0.0097 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sigma54_activ_2 PF14532.6 GAX27756.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NAD_binding_2 PF03446.15 GAX27756.1 - 0.022 14.9 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 GAX27756.1 - 0.043 13.9 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 GAX27756.1 - 0.046 14.3 0.0 0.15 12.6 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LSM PF01423.22 GAX27757.1 - 1.6e-18 66.2 0.0 1.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain MOSC PF03473.17 GAX27758.1 - 4e-27 94.8 0.0 6.5e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 GAX27758.1 - 7e-15 55.0 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF1415 PF07209.12 GAX27759.1 - 7.8e-51 172.2 0.0 1.1e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) Ribosomal_L7Ae PF01248.26 GAX27760.1 - 2.5e-22 78.4 0.1 3.9e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2229 PF09989.9 GAX27760.1 - 0.13 11.9 0.4 0.93 9.1 0.0 1.9 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3783 PF12646.7 GAX27761.1 - 0.00016 21.5 0.0 0.00051 19.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3783) PhyH PF05721.13 GAX27762.1 - 3.3e-13 50.4 1.7 7.1e-13 49.3 0.1 2.2 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) L_HMGIC_fpl PF10242.9 GAX27764.1 - 0.00023 21.4 1.7 0.00031 21.0 1.7 1.2 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF2593 PF10767.9 GAX27764.1 - 0.2 11.7 4.2 0.3 11.1 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) DUF2976 PF11190.8 GAX27764.1 - 0.22 11.3 0.6 0.52 10.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) JAB PF01398.21 GAX27765.1 - 1.5e-16 60.5 0.0 2.8e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 GAX27765.1 - 0.0056 16.4 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Methyltransf_11 PF08241.12 GAX27766.1 - 4.8e-10 40.0 0.0 7.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX27766.1 - 2.5e-06 28.1 0.0 9.3e-06 26.3 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX27766.1 - 7.3e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAX27766.1 - 0.00023 21.1 0.0 0.00034 20.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX27766.1 - 0.00046 20.9 0.0 0.00086 20.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX27766.1 - 0.00077 19.3 0.0 0.0013 18.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GAX27766.1 - 0.024 13.2 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 GAX27766.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase DREV PF05219.12 GAX27766.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase DUF842 PF05811.13 GAX27767.1 - 6.8e-30 103.5 6.1 8.3e-30 103.2 6.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) ApoO PF09769.9 GAX27767.1 - 0.039 13.9 0.2 1.7 8.6 0.1 2.3 1 1 0 2 2 2 0 Apolipoprotein O DUF2407_C PF13373.6 GAX27767.1 - 0.055 13.6 0.1 0.08 13.1 0.1 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Arf PF00025.21 GAX27768.1 - 0.0023 17.4 0.3 0.012 15.0 0.3 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Peptidase_S49_N PF08496.10 GAX27768.1 - 0.097 12.7 15.0 0.88 9.6 14.0 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Proteasome PF00227.26 GAX27769.1 - 1.3e-56 191.1 0.0 1.8e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX27769.1 - 7.1e-14 51.2 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RRM_1 PF00076.22 GAX27770.1 - 4e-20 71.4 0.0 2.2e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX27770.1 - 3.3e-05 23.5 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 GAX27770.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) KorB_C PF06613.11 GAX27770.1 - 0.1 12.6 0.0 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain TylF PF05711.11 GAX27772.1 - 2e-09 37.1 0.0 1.1e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Macrocin-O-methyltransferase (TylF) TPR_2 PF07719.17 GAX27772.1 - 3.6e-07 29.8 0.7 0.68 10.2 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX27772.1 - 6.1e-06 26.0 0.3 5.3 7.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX27772.1 - 9e-06 25.3 0.2 1.5 8.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX27772.1 - 1.7e-05 25.2 1.8 0.00041 20.8 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX27772.1 - 2.6e-05 24.4 1.4 0.18 12.1 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_24 PF13578.6 GAX27772.1 - 0.00017 22.6 0.0 0.00061 20.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain TPR_14 PF13428.6 GAX27772.1 - 0.00017 22.1 3.6 0.44 11.5 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX27772.1 - 0.00025 20.7 0.2 0.0011 18.5 0.0 2.3 3 0 0 3 3 3 1 TPR repeat TPR_10 PF13374.6 GAX27772.1 - 0.0024 17.7 0.3 5.5 7.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX27772.1 - 0.0032 17.7 0.0 7.5 7.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX27772.1 - 0.0047 17.5 1.4 12 6.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX27772.1 - 0.0048 17.5 0.7 0.67 10.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DHHC PF01529.20 GAX27773.1 - 9.8e-26 90.5 12.9 9.8e-26 90.5 12.9 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Peptidase_S24 PF00717.23 GAX27775.1 - 5.1e-08 32.8 0.3 1.4e-06 28.2 0.3 2.3 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 GAX27775.1 - 7.7e-06 25.7 0.3 0.0014 18.4 0.0 2.9 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 PrmA PF06325.13 GAX27775.1 - 0.037 13.4 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) H_PPase PF03030.16 GAX27776.1 - 2.3e-240 799.7 32.8 2.5e-240 799.6 32.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Peptidase_S26 PF10502.9 GAX27777.1 - 3.6e-06 26.8 0.0 0.0001 22.1 0.0 2.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 GAX27777.1 - 2.1e-05 24.4 0.0 0.00015 21.6 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like DUF563 PF04577.14 GAX27778.1 - 1.1e-20 74.6 0.0 1.5e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Homoserine_dh PF00742.19 GAX27779.1 - 2.5e-55 187.0 0.1 5.2e-55 186.0 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GAX27779.1 - 2.6e-16 60.3 0.7 9.1e-16 58.6 0.1 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAX27779.1 - 0.0012 19.1 0.2 0.003 17.8 0.2 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 GAX27779.1 - 0.0066 17.3 0.1 0.02 15.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 GAX27779.1 - 0.1 13.0 0.3 0.29 11.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Response_reg PF00072.24 GAX27780.1 - 1.1e-27 96.4 0.1 2.3e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAX27780.1 - 6.7e-24 84.6 0.3 6.6e-23 81.4 0.0 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 GAX27780.1 - 1e-14 55.0 0.0 2.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 GAX27780.1 - 7.7e-13 48.3 0.1 4.4e-12 45.9 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 GAX27780.1 - 5.6e-07 30.2 0.0 1.2e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 GAX27780.1 - 0.0019 18.0 0.0 0.0076 16.1 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FlaC_arch PF05377.11 GAX27780.1 - 1.4 9.4 5.6 0.52 10.7 0.8 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bot1p PF12298.8 GAX27781.1 - 0.00049 20.3 0.1 0.00049 20.3 0.1 1.9 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Mrr_N PF14338.6 GAX27781.1 - 0.023 14.8 0.5 0.084 13.0 0.0 2.2 2 0 0 2 2 2 0 Mrr N-terminal domain RRM_1 PF00076.22 GAX27782.1 - 2.5e-14 52.9 0.0 3.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF305 PF03713.13 GAX27783.1 - 1.3e-09 38.4 0.1 1.5e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF305) Dehydratase_LU PF02286.15 GAX27783.1 - 0.05 12.2 0.0 0.055 12.1 0.0 1.0 1 0 0 1 1 1 0 Dehydratase large subunit DUF3677 PF12432.8 GAX27784.1 - 0.00014 22.1 0.1 0.00066 20.0 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) 2OG-FeII_Oxy_3 PF13640.6 GAX27785.1 - 1.7e-15 57.7 0.0 2.7e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAX27785.1 - 9.1e-11 42.3 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EcoRII-C PF09019.11 GAX27785.1 - 0.076 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 EcoRII C terminal G6PD_C PF02781.16 GAX27787.1 - 9.9e-98 326.9 0.0 1.4e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAX27787.1 - 7e-58 196.2 0.0 1e-57 195.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RVT_2 PF07727.14 GAX27787.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HA PF03457.14 GAX27788.1 - 3.2e-37 126.7 1.4 4e-20 71.9 0.5 2.5 2 0 0 2 2 2 2 Helicase associated domain DUF2153 PF09921.9 GAX27788.1 - 0.061 13.1 0.3 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) Topo_Zn_Ribbon PF08272.11 GAX27788.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF3246 PF11596.8 GAX27788.1 - 0.13 11.7 1.8 0.2 11.1 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Aldo_ket_red PF00248.21 GAX27789.1 - 1.4e-46 159.0 0.1 1.9e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AAA_12 PF13087.6 GAX27790.1 - 9.9e-35 120.0 0.0 1.7e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX27790.1 - 6e-20 72.1 0.0 1.4e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAX27790.1 - 2.7e-09 37.5 0.0 1.2e-08 35.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX27790.1 - 1e-08 35.1 0.0 7.1e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 GAX27790.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain HMG_box PF00505.19 GAX27791.1 - 0.09 13.2 0.2 0.09 13.2 0.2 2.7 2 1 1 3 3 3 0 HMG (high mobility group) box SVIP PF15811.5 GAX27791.1 - 1.7 9.2 8.6 1.6 9.3 0.2 3.2 3 0 0 3 3 3 0 Small VCP/p97-interacting protein Pro_dh PF01619.18 GAX27792.1 - 8.1e-83 278.3 0.1 2.6e-82 276.7 0.1 1.9 1 1 1 2 2 2 1 Proline dehydrogenase EF-hand_1 PF00036.32 GAX27792.1 - 1.4e-05 24.3 0.7 4.4e-05 22.7 0.7 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX27792.1 - 9.2e-05 22.1 1.7 0.00023 20.9 0.8 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GAX27792.1 - 0.00042 19.7 0.4 0.0011 18.4 0.4 1.7 1 0 0 1 1 1 1 EF hand AP_endonuc_2 PF01261.24 GAX27792.1 - 0.0074 15.8 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel EF-hand_7 PF13499.6 GAX27792.1 - 0.008 16.6 0.1 0.022 15.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX27792.1 - 0.02 14.7 0.1 0.049 13.5 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF1825 PF08855.10 GAX27793.1 - 8e-18 64.3 1.3 1e-12 47.9 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1825) ROS_MUCR PF05443.11 GAX27793.1 - 0.016 15.2 0.5 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf_C2H2_6 PF18450.1 GAX27793.1 - 0.09 12.5 0.2 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Zinc Finger domain Trypsin PF00089.26 GAX27794.1 - 1.5e-38 132.9 0.0 1.9e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAX27794.1 - 3.5e-05 24.7 0.1 0.00011 23.1 0.0 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain MatE PF01554.18 GAX27795.1 - 2.9e-11 43.3 20.9 4.2e-09 36.3 1.8 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAX27795.1 - 2.9e-07 30.6 1.6 2.9e-07 30.6 1.6 3.6 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Pik1 PF11522.8 GAX27795.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 SpoU_methylase PF00588.19 GAX27796.1 - 3.2e-27 95.4 0.0 4.9e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family Syntaxin-6_N PF09177.11 GAX27796.1 - 0.052 14.1 0.3 0.13 12.8 0.1 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CHD5 PF04420.14 GAX27797.1 - 0.18 11.7 3.5 0.49 10.2 3.5 1.6 1 1 0 1 1 1 0 CHD5-like protein DUF4140 PF13600.6 GAX27797.1 - 0.31 11.5 2.2 0.58 10.6 2.2 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Peptidase_S41 PF03572.18 GAX27798.1 - 1.3e-42 145.2 0.5 2e-42 144.6 0.5 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 GAX27798.1 - 4.2e-11 43.0 0.4 1.1e-10 41.7 0.4 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX27798.1 - 4.3e-08 32.9 0.1 1.2e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX27798.1 - 2.8e-07 30.8 0.2 5.2e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_C1 PF14684.6 GAX27798.1 - 8.7e-07 28.9 1.0 1.5e-06 28.2 1.0 1.3 1 0 0 1 1 1 1 Tricorn protease C1 domain PseudoU_synth_1 PF01416.20 GAX27799.1 - 6.9e-19 68.3 0.0 4.3e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 GAX27799.1 - 0.0048 16.8 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Peptidase_C1 PF00112.23 GAX27800.1 - 3.8e-70 236.4 0.4 5.9e-70 235.8 0.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX27800.1 - 3e-15 56.4 2.5 5.1e-15 55.7 2.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAX27800.1 - 2.8e-05 23.1 0.5 0.038 12.8 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF677 PF05055.12 GAX27800.1 - 0.25 10.2 0.0 0.48 9.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF677) zf-CCHC_4 PF14392.6 GAX27801.1 - 0.059 13.1 0.9 0.15 11.8 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle SpoIIIAH PF12685.7 GAX27804.1 - 0.16 11.8 6.8 0.094 12.5 1.6 2.6 3 0 0 3 3 3 0 SpoIIIAH-like protein Zip PF02535.22 GAX27805.1 - 3.6e-37 128.4 21.7 1.1e-25 90.6 9.6 2.4 2 1 1 3 3 3 2 ZIP Zinc transporter DUF1129 PF06570.11 GAX27805.1 - 0.24 10.9 3.0 0.094 12.2 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Polysacc_deac_1 PF01522.21 GAX27805.1 - 5.8 6.8 7.1 0.16 11.9 0.7 1.6 2 0 0 2 2 2 0 Polysaccharide deacetylase zf-MYND PF01753.18 GAX27806.1 - 5.1e-06 26.5 21.1 5.4e-06 26.4 18.9 2.1 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 GAX27807.1 - 2.7e-06 27.4 18.7 5.1e-06 26.5 18.7 1.5 1 0 0 1 1 1 1 MYND finger Slu7 PF11708.8 GAX27808.1 - 3.1e-82 276.3 11.0 3.1e-82 276.3 11.0 2.6 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor Plus-3 PF03126.18 GAX27808.1 - 0.056 14.0 0.1 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 Plus-3 domain Trypsin_2 PF13365.6 GAX27809.1 - 2.7e-33 116.0 0.5 4.9e-33 115.1 0.5 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAX27809.1 - 1.4e-14 54.5 0.1 3.7e-14 53.1 0.1 1.7 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 GAX27809.1 - 3.6e-12 46.4 0.1 7.2e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX27809.1 - 7.6e-05 22.5 4.3 0.0068 16.2 0.4 2.6 2 0 0 2 2 2 2 PDZ domain Peptidase_S29 PF02907.15 GAX27809.1 - 0.0021 17.8 0.2 0.016 15.0 0.0 2.3 2 1 2 4 4 4 1 Hepatitis C virus NS3 protease PDZ PF00595.24 GAX27809.1 - 0.008 16.5 3.1 0.38 11.2 3.1 2.7 1 1 0 1 1 1 1 PDZ domain Peptidase_S32 PF05579.13 GAX27809.1 - 0.01 15.1 0.3 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 GAX27809.1 - 0.032 12.9 0.6 0.26 9.9 0.5 1.9 2 0 0 2 2 2 0 Peptidase S46 GRASP55_65 PF04495.14 GAX27809.1 - 0.065 13.6 0.0 0.44 10.9 0.0 2.1 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain MCM2_N PF12619.8 GAX27813.1 - 0.011 16.0 5.3 0.011 16.0 5.3 2.4 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 DUF5486 PF17588.2 GAX27813.1 - 0.47 10.4 2.6 1.5 8.7 2.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Brix PF04427.18 GAX27814.1 - 3.1e-29 102.5 0.1 4.1e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.25 GAX27816.1 - 3.9e-23 81.3 0.3 7.6e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 GAX27816.1 - 3.6e-12 46.5 0.2 1.3e-10 41.5 0.2 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX27816.1 - 1.5e-08 34.7 0.0 3.5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX27816.1 - 5.4e-08 33.1 0.1 1e-07 32.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX27816.1 - 0.035 14.1 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 GAX27816.1 - 0.076 13.1 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 GAX27816.1 - 0.22 10.9 4.2 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Trp_Tyr_perm PF03222.13 GAX27817.1 - 6e-33 114.4 23.5 6.3e-29 101.2 16.1 3.4 1 1 1 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 GAX27817.1 - 0.0017 17.1 5.8 0.0017 17.1 5.8 2.0 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Cnl2_NKP2 PF09447.10 GAX27817.1 - 0.062 13.5 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Peptidase_S49_N PF08496.10 GAX27818.1 - 0.17 12.0 2.2 0.72 9.9 0.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Sad1_UNC PF07738.13 GAX27819.1 - 1.3e-19 70.5 0.0 2.4e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CBS PF00571.28 GAX27820.1 - 5.5e-14 52.4 0.0 4.1e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain SpoIIE PF07228.12 GAX27820.1 - 1.8e-08 34.5 0.0 4.6e-07 29.9 0.0 2.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAX27820.1 - 4.2e-07 29.9 0.0 0.0039 16.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C DnaJ_C PF01556.18 GAX27821.1 - 5.4e-41 140.1 0.0 1.1e-40 139.1 0.0 1.5 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX27821.1 - 7.4e-25 86.9 1.3 1.3e-24 86.1 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAX27821.1 - 4.5e-12 46.1 19.8 9.5e-12 45.1 19.8 1.6 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.7 GAX27821.1 - 0.34 11.0 11.2 1.8 8.7 11.2 2.0 1 1 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 GAX27821.1 - 0.47 10.1 5.7 0.37 10.4 0.5 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Anti-TRAP PF15777.5 GAX27821.1 - 0.87 9.6 19.8 3.4 7.7 4.6 3.4 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 GAX27821.1 - 1.1 9.3 7.0 2.3 8.3 7.0 1.5 1 0 0 1 1 1 0 zinc-ribbons zinc_ribbon_15 PF17032.5 GAX27821.1 - 4.5 8.1 7.7 10 7.0 7.7 1.6 1 1 0 1 1 1 0 zinc-ribbon family HAD_2 PF13419.6 GAX27822.1 - 3.6e-05 23.9 0.9 0.077 13.1 0.1 3.3 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX27822.1 - 0.00012 22.1 0.0 0.00027 20.9 0.0 1.7 1 1 0 1 1 1 1 HAD-hyrolase-like NADase_NGA PF07461.11 GAX27822.1 - 0.0054 15.7 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Nicotine adenine dinucleotide glycohydrolase (NADase) CK2S PF15011.6 GAX27822.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Casein Kinase 2 substrate RVT_2 PF07727.14 GAX27825.1 - 1.3e-20 74.1 0.2 6e-20 71.9 0.2 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX27825.1 - 9.1e-05 22.4 1.9 0.00026 20.9 1.9 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 GAX27825.1 - 0.098 12.4 2.0 0.18 11.6 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger FAD_binding_3 PF01494.19 GAX27826.1 - 8.9e-27 94.2 0.0 1.2e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAX27826.1 - 2.5e-05 23.7 0.1 0.16 11.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX27826.1 - 7.6e-05 22.4 0.8 0.0085 15.7 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAX27826.1 - 0.00077 19.6 0.1 0.0022 18.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAX27826.1 - 0.0008 19.9 0.7 1.6 9.3 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAX27826.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 GAX27826.1 - 0.059 12.2 0.2 0.41 9.4 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 GAX27826.1 - 0.094 11.4 0.7 1.6 7.3 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein HU-DNA_bdg PF14848.6 GAX27827.1 - 0.05 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 DNA-binding domain VCBS PF13517.6 GAX27828.1 - 6.1e-12 45.9 7.8 0.00067 20.2 0.3 5.9 5 1 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAX27828.1 - 6.6e-05 23.0 18.7 0.0056 16.8 1.5 4.3 4 0 0 4 4 4 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 GAX27828.1 - 0.042 13.2 1.2 8.7 5.7 0.0 3.6 4 0 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 GAX27828.1 - 0.45 10.7 5.8 19 5.6 0.1 4.5 4 1 0 4 4 4 0 Dockerin type I domain Nucleo_P87 PF07267.11 GAX27828.1 - 2.3 7.0 6.0 3.4 6.4 6.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MoCF_biosynth PF00994.24 GAX27830.1 - 4.5e-26 91.2 0.1 7.3e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF1244 PF06844.11 GAX27830.1 - 5.9e-24 84.0 8.4 3.6e-12 46.3 0.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1244) TCRP1 PF14944.6 GAX27830.1 - 0.035 14.1 2.6 0.056 13.4 2.6 1.4 1 1 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 GAD-like PF08887.11 GAX27831.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 GAD-like domain Pet20 PF08692.10 GAX27831.1 - 0.37 11.5 3.9 0.38 11.5 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial protein Pet20 SOAR PF16533.5 GAX27831.1 - 0.89 9.6 10.2 5 7.1 0.0 3.6 2 1 0 3 3 3 0 STIM1 Orai1-activating region KCT2 PF17818.1 GAX27831.1 - 1.6 8.8 6.5 0.31 11.2 2.3 1.8 2 0 0 2 2 2 0 Keratinocyte-associated gene product CwfJ_C_1 PF04677.15 GAX27832.1 - 1e-19 70.6 0.0 1.5e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 GAX27832.1 - 2.3e-19 70.1 0.2 1.4e-18 67.6 0.1 2.2 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CRAL_TRIO PF00650.20 GAX27833.1 - 3.9e-11 42.9 0.0 6.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain adh_short PF00106.25 GAX27834.1 - 3.2e-08 33.3 2.1 1.7e-05 24.4 1.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX27834.1 - 1.5e-06 28.0 1.6 5.1e-06 26.2 0.3 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAX27834.1 - 0.00045 19.8 1.0 0.023 14.1 0.1 3.1 3 1 0 4 4 4 1 NAD dependent epimerase/dehydratase family Glycos_transf_2 PF00535.26 GAX27835.1 - 1.6e-17 63.9 0.0 2.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX27835.1 - 3.3e-08 33.7 0.0 8.5e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GAX27835.1 - 0.00019 21.9 0.0 0.00038 20.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAX27835.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 tRNA_lig_CPD PF08302.11 GAX27835.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain SH3_10 PF17902.1 GAX27835.1 - 0.2 11.8 1.4 4.2 7.5 0.0 3.3 3 1 1 4 4 4 0 SH3 domain Aminotran_3 PF00202.21 GAX27836.1 - 9.1e-68 228.8 0.0 1.1e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Mpv17_PMP22 PF04117.12 GAX27837.1 - 0.3 11.4 1.3 14 6.0 0.0 3.1 3 0 0 3 3 3 0 Mpv17 / PMP22 family Rib_5-P_isom_A PF06026.14 GAX27838.1 - 7.9e-66 220.9 0.0 1e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 GAX27838.1 - 0.042 13.8 0.0 1.3 9.0 0.0 2.2 1 1 0 2 2 2 0 DeoR C terminal sensor domain PC-Esterase PF13839.6 GAX27839.1 - 1e-10 41.8 2.8 0.00092 19.0 0.5 3.7 2 2 2 4 4 4 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF4242 PF14026.6 GAX27841.1 - 0.052 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Methyltransf_23 PF13489.6 GAX27842.1 - 4.7e-14 52.5 0.0 8.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX27842.1 - 7.9e-10 38.7 0.0 7e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX27842.1 - 2e-08 34.9 0.0 2.4e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX27842.1 - 2.3e-08 34.6 0.0 1.5e-05 25.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAX27842.1 - 3.2e-08 34.1 0.0 1.6e-06 28.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 GAX27842.1 - 0.00046 19.4 0.0 0.027 13.6 0.0 2.2 1 1 1 2 2 2 1 DREV methyltransferase MTS PF05175.14 GAX27842.1 - 0.0012 18.4 0.0 0.0047 16.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 GAX27842.1 - 0.0058 16.1 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 Tellurite resistance protein TehB NodS PF05401.11 GAX27842.1 - 0.085 12.5 0.0 0.24 11.0 0.0 1.6 1 1 1 2 2 2 0 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 GAX27842.1 - 0.093 12.3 0.1 0.25 10.9 0.1 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 GAX27842.1 - 0.12 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TAF PF02969.17 GAX27842.1 - 0.16 12.1 0.3 3.7 7.8 0.0 2.3 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Pro_isomerase PF00160.21 GAX27843.1 - 1.5e-38 132.5 0.0 1.8e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD V-SNARE_C PF12352.8 GAX27844.1 - 1.6e-09 37.9 0.7 1.6e-09 37.9 0.7 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAX27844.1 - 0.00016 21.5 0.2 0.00016 21.5 0.2 2.2 1 1 1 2 2 2 1 Sec20 FUSC PF04632.12 GAX27844.1 - 0.064 11.8 3.5 0.076 11.5 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Flavodoxin_1 PF00258.25 GAX27844.1 - 0.095 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin Exonuc_VII_L PF02601.15 GAX27844.1 - 1.1 8.8 7.3 1.2 8.6 7.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Alpha_kinase PF02816.18 GAX27845.1 - 3.5e-12 46.8 0.0 5.3e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Alpha-kinase family VWA_2 PF13519.6 GAX27845.1 - 0.00036 21.1 0.0 0.00087 19.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3253 PF11625.8 GAX27845.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) WW PF00397.26 GAX27846.1 - 5.4e-22 77.6 23.0 4.5e-13 49.0 3.4 3.9 4 0 0 4 4 4 3 WW domain DEAD PF00270.29 GAX27847.1 - 1.4e-19 70.5 0.1 1.7e-17 63.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX27847.1 - 1e-18 67.7 0.0 2.4e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAX27847.1 - 1e-08 35.8 2.5 2.6e-08 34.5 1.4 2.3 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 GAX27847.1 - 5.7e-05 23.2 0.0 0.0008 19.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HRDC PF00570.23 GAX27847.1 - 0.069 13.2 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 HRDC domain RNA_pol_Rpb4 PF03874.16 GAX27849.1 - 4.9e-09 36.6 0.3 6.6e-09 36.1 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 TraF_2 PF13729.6 GAX27849.1 - 0.004 16.6 0.5 0.015 14.6 0.4 1.7 1 1 1 2 2 2 2 F plasmid transfer operon, TraF, protein DUF3387 PF11867.8 GAX27849.1 - 0.011 15.1 0.7 0.013 14.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) NleF_casp_inhib PF16809.5 GAX27849.1 - 0.016 15.1 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 NleF caspase inhibitor PEP-utilisers_N PF05524.13 GAX27849.1 - 0.027 14.6 2.6 0.056 13.6 2.3 1.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4972 PF16342.5 GAX27849.1 - 0.029 14.1 0.1 0.064 13.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) DUF1729 PF08354.10 GAX27849.1 - 0.038 12.9 0.1 0.046 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) CdiI_2 PF18593.1 GAX27849.1 - 0.11 13.1 0.8 0.31 11.7 0.5 1.8 1 1 1 2 2 2 0 CdiI immunity protein LprI PF07007.12 GAX27849.1 - 0.12 13.0 0.1 0.15 12.7 0.1 1.2 1 0 0 1 1 1 0 Lysozyme inhibitor LprI cobW PF02492.19 GAX27850.1 - 9.4e-37 126.3 5.8 5.2e-25 88.1 1.2 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX27850.1 - 4e-07 29.9 0.0 7.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAX27850.1 - 7.4e-05 22.7 0.8 0.17 11.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Viral_helicase1 PF01443.18 GAX27850.1 - 0.0019 18.0 0.1 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 GAX27850.1 - 0.0047 17.0 1.0 0.022 14.9 1.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 GAX27850.1 - 0.0059 16.6 0.1 0.01 15.7 0.1 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 GAX27850.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX27850.1 - 0.031 14.8 0.5 0.075 13.6 0.5 1.8 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 GAX27850.1 - 0.034 14.5 0.1 0.066 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Rod_C PF10493.9 GAX27850.1 - 0.042 12.3 0.1 0.055 11.8 0.1 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region AAA_14 PF13173.6 GAX27850.1 - 0.054 13.5 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX27850.1 - 0.069 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAX27850.1 - 0.094 11.8 0.9 0.12 11.4 0.1 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 GAX27850.1 - 0.12 12.6 0.1 0.32 11.2 0.0 1.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 GAX27850.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 GAX27850.1 - 0.27 11.7 5.4 0.53 10.7 0.6 2.3 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 GAX27850.1 - 0.29 10.6 2.0 6.6 6.2 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 GAX27851.1 - 7.2e-56 188.6 0.9 9.8e-56 188.1 0.9 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAX27851.1 - 4.9e-18 64.9 0.0 8.2e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAX27851.1 - 0.00072 19.5 0.4 1.2 9.1 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 GAX27851.1 - 0.0036 16.8 0.9 0.11 11.9 0.2 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family T2SSE PF00437.20 GAX27851.1 - 0.016 14.3 1.0 0.032 13.3 0.2 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 GAX27851.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 GAX27851.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAX27851.1 - 0.034 14.5 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 GAX27851.1 - 0.057 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 GAX27851.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX27851.1 - 0.083 13.0 0.6 0.34 11.0 0.6 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 GAX27851.1 - 0.088 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.14 GAX27851.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 GAX27851.1 - 0.1 12.1 3.2 1.6 8.3 3.2 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 GAX27851.1 - 0.14 12.7 0.1 0.29 11.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 GAX27851.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX27851.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 GAX27851.1 - 6.8 7.1 10.6 84 3.6 10.6 2.2 1 1 0 1 1 1 0 AAA domain RNase_HII PF01351.18 GAX27852.1 - 3e-18 66.4 0.0 5.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease HII Methyltransf_11 PF08241.12 GAX27852.1 - 3.7e-09 37.1 0.0 7.9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX27852.1 - 9.1e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAX27852.1 - 5.4e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX27852.1 - 5.7e-05 23.8 0.0 0.00013 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX27852.1 - 0.0086 16.8 0.0 0.022 15.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ssDNA_DBD PF18333.1 GAX27852.1 - 0.022 14.9 0.5 0.12 12.4 1.3 1.9 2 0 0 2 2 2 0 Non-canonical single-stranded DNA-binding domain Methyltransf_8 PF05148.15 GAX27852.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_23 PF13489.6 GAX27852.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain KTI12 PF08433.10 GAX27853.1 - 7.3e-16 58.4 0.2 1.4e-15 57.4 0.2 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAX27853.1 - 6.4e-12 45.8 0.2 2.7e-11 43.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAX27853.1 - 1.3e-05 25.3 0.1 2.7e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX27853.1 - 2e-05 25.2 0.1 8.9e-05 23.0 0.0 2.2 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 GAX27853.1 - 9.9e-05 21.7 0.0 0.00021 20.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 GAX27853.1 - 0.00016 22.0 1.0 0.00048 20.4 0.1 2.4 3 1 0 3 3 3 1 AAA domain APS_kinase PF01583.20 GAX27853.1 - 0.0019 18.1 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase IstB_IS21 PF01695.17 GAX27853.1 - 0.0024 17.6 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 GAX27853.1 - 0.0025 18.2 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 GAX27853.1 - 0.0032 17.7 0.0 0.0096 16.1 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATPase PF06745.13 GAX27853.1 - 0.004 16.5 0.0 0.0085 15.5 0.0 1.7 2 0 0 2 2 2 1 KaiC dNK PF01712.19 GAX27853.1 - 0.0061 16.4 0.1 0.39 10.5 0.1 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase NB-ARC PF00931.22 GAX27853.1 - 0.007 15.6 1.6 0.042 13.0 0.1 2.7 2 1 1 3 3 3 1 NB-ARC domain G-alpha PF00503.20 GAX27853.1 - 0.008 15.4 0.7 0.015 14.5 0.4 1.6 1 1 0 1 1 1 1 G-protein alpha subunit TsaE PF02367.17 GAX27853.1 - 0.01 15.9 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAX27853.1 - 0.015 15.7 2.1 0.046 14.1 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 GAX27853.1 - 0.016 15.0 0.4 0.18 11.5 0.0 2.4 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 GAX27853.1 - 0.025 15.1 0.2 0.068 13.7 0.0 1.9 2 1 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 GAX27853.1 - 0.038 13.9 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase CPT PF07931.12 GAX27853.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 GAX27853.1 - 0.042 13.6 0.0 0.077 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAX27853.1 - 0.046 14.1 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase DUF2939 PF11159.8 GAX27853.1 - 0.047 14.1 0.1 0.2 12.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) cobW PF02492.19 GAX27853.1 - 0.053 13.1 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 GAX27853.1 - 0.056 13.9 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX27853.1 - 0.061 13.3 0.0 0.21 11.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAX27853.1 - 0.07 12.5 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 GAX27853.1 - 0.084 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 GAX27853.1 - 0.093 12.2 6.4 0.34 10.4 1.1 2.4 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GAX27853.1 - 0.093 12.3 1.6 0.48 10.0 0.1 2.4 2 2 0 2 2 2 0 AAA domain SKI PF01202.22 GAX27853.1 - 0.11 12.6 0.5 59 3.8 0.1 3.6 3 1 1 4 4 3 0 Shikimate kinase Mem_trans PF03547.18 GAX27854.1 - 0.007 14.8 0.2 0.01 14.2 0.0 1.4 2 0 0 2 2 2 1 Membrane transport protein 7TM_GPCR_Srab PF10292.9 GAX27854.1 - 0.09 11.7 0.1 0.17 10.8 0.0 1.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor ECF_trnsprt PF12822.7 GAX27854.1 - 0.33 11.0 4.5 0.12 12.5 0.9 2.0 2 1 0 2 2 2 0 ECF transporter, substrate-specific component DUF2142 PF09913.9 GAX27854.1 - 1.2 8.0 5.2 0.081 11.8 0.3 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) VPS13_C PF16909.5 GAX27855.1 - 9.6e-39 133.0 1.2 4e-34 117.9 0.3 3.1 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 GAX27855.1 - 8e-21 74.6 0.2 1e-05 25.1 0.0 3.9 3 0 0 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 GAX27855.1 - 2.3e-19 69.6 1.3 1e-18 67.5 0.3 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 C2 PF00168.30 GAX27855.1 - 2.9e-16 59.6 0.2 7.6e-14 51.9 0.0 3.7 2 1 0 2 2 2 1 C2 domain VPS13 PF16908.5 GAX27855.1 - 0.0025 17.7 0.8 0.0059 16.4 0.8 1.6 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal PDZ_6 PF17820.1 GAX27855.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 GAX27855.1 - 0.079 13.3 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 GAX27855.1 - 0.18 12.2 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain ABC2_membrane PF01061.24 GAX27856.1 - 3.8e-37 127.8 17.5 6.3e-37 127.0 17.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX27856.1 - 8e-21 75.0 0.0 1.3e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAX27856.1 - 4.1e-12 45.9 7.5 6.9e-12 45.1 7.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAX27856.1 - 8e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 GAX27856.1 - 9.4e-05 22.4 0.0 0.34 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX27856.1 - 0.0065 15.9 0.0 0.046 13.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAX27856.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAX27856.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAX27856.1 - 0.028 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAX27856.1 - 0.047 14.2 0.0 0.094 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAX27856.1 - 0.049 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAX27856.1 - 0.058 13.0 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAX27856.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FKBP_C PF00254.28 GAX27857.1 - 3.1e-09 37.0 0.0 8.4e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 GAX27857.1 - 3.9e-05 23.3 0.3 0.00011 21.9 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX27857.1 - 0.00048 20.0 2.4 0.0016 18.4 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX27857.1 - 0.00083 19.4 0.9 0.0036 17.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX27857.1 - 0.0027 18.0 1.3 2.2 8.9 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX27857.1 - 0.049 13.7 0.6 0.31 11.1 0.2 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF1957 PF09210.11 GAX27857.1 - 0.12 12.8 2.9 0.11 12.9 0.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1957) Fcf2 PF08698.11 GAX27858.1 - 2.6e-28 98.3 0.1 2.6e-28 98.3 0.1 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing baeRF_family10 PF18854.1 GAX27858.1 - 0.036 14.3 1.5 0.058 13.6 1.5 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Cytochrom_B561 PF03188.16 GAX27859.1 - 1.6e-13 51.0 5.9 3.1e-13 50.0 5.9 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 GAX27859.1 - 0.013 15.6 3.1 0.12 12.6 3.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Tetraspanin PF00335.20 GAX27859.1 - 6.9 6.3 9.4 35 4.0 9.4 2.0 1 1 0 1 1 1 0 Tetraspanin family FTR1 PF03239.14 GAX27860.1 - 7.9e-10 38.4 9.0 7.9e-10 38.4 9.0 1.9 2 1 0 2 2 2 1 Iron permease FTR1 family PrgI PF12666.7 GAX27860.1 - 0.0064 17.2 2.6 0.52 11.1 0.4 2.7 3 0 0 3 3 3 1 PrgI family protein Wzy_C PF04932.15 GAX27860.1 - 0.057 13.0 2.0 1 9.0 0.1 2.3 2 0 0 2 2 2 0 O-Antigen ligase DUF4231 PF14015.6 GAX27860.1 - 0.28 11.7 3.8 8.8 6.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3796 PF12676.7 GAX27860.1 - 0.72 10.3 4.3 0.54 10.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) PHO4 PF01384.20 GAX27860.1 - 0.86 8.6 3.4 2.7 7.0 0.2 2.1 2 0 0 2 2 2 0 Phosphate transporter family DUF3792 PF12670.7 GAX27860.1 - 1.2 9.3 11.5 3.2 7.9 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) SPC12 PF06645.13 GAX27860.1 - 2.9 8.1 11.2 3.5 7.8 2.6 3.5 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Epimerase PF01370.21 GAX27861.1 - 1.9e-09 37.3 0.0 2.7e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAX27861.1 - 4.9e-06 25.8 0.0 6.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Cofac_haem_bdg PF04187.13 GAX27862.1 - 2.2e-45 155.3 0.0 1.6e-44 152.5 0.0 2.0 2 0 0 2 2 2 1 Haem-binding uptake, Tiki superfamily, ChaN HSF_DNA-bind PF00447.17 GAX27863.1 - 4.6e-18 65.6 0.5 8.4e-18 64.8 0.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.17 GAX27864.1 - 6.6e-18 65.1 0.5 1.2e-17 64.3 0.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DGF-1_C PF11040.8 GAX27865.1 - 0.096 12.7 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus FliH PF02108.16 GAX27866.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH DNA_ligase_A_M PF01068.21 GAX27867.1 - 4.4e-53 180.0 0.1 8.5e-53 179.0 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAX27867.1 - 1e-38 133.4 0.2 1e-38 133.4 0.2 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAX27867.1 - 5.2e-24 84.7 0.0 1.5e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 GAX27867.1 - 8.3e-05 23.0 0.1 0.00017 21.9 0.1 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 GAX27867.1 - 0.041 13.9 0.2 4 7.5 0.0 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain CDC45 PF02724.14 GAX27867.1 - 7.3 4.7 13.9 14 3.8 13.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Cupin_8 PF13621.6 GAX27868.1 - 1.4e-39 136.3 0.1 2.6e-39 135.5 0.1 1.4 1 0 0 1 1 1 1 Cupin-like domain SET PF00856.28 GAX27868.1 - 1.6e-10 41.6 1.0 1.4e-09 38.5 0.1 2.8 2 1 0 2 2 2 1 SET domain Cupin_4 PF08007.12 GAX27868.1 - 2.4e-10 40.4 0.4 9.8e-10 38.4 0.4 2.0 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 GAX27868.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 GAX27868.1 - 0.018 14.8 0.0 0.071 12.8 0.0 2.0 1 0 0 1 1 1 0 Cupin domain SID-1_RNA_chan PF13965.6 GAX27869.1 - 1.2 7.4 4.9 1.9 6.8 4.9 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4491 PF14898.6 GAX27870.1 - 0.32 11.5 1.5 23 5.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) PLAC8 PF04749.17 GAX27871.1 - 3.1e-13 50.6 21.5 4.7e-13 50.0 21.5 1.3 1 0 0 1 1 1 1 PLAC8 family PRA1 PF03208.19 GAX27871.1 - 0.064 12.9 0.8 0.097 12.3 0.8 1.2 1 0 0 1 1 1 0 PRA1 family protein DUF1129 PF06570.11 GAX27871.1 - 0.084 12.4 1.1 0.12 11.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) LRR_8 PF13855.6 GAX27872.1 - 6.4e-17 61.1 10.7 7.7e-06 25.6 4.8 4.5 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAX27872.1 - 1.2e-15 57.3 15.9 0.00011 22.6 2.4 5.8 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX27872.1 - 6e-09 35.2 12.9 1.4 9.8 0.1 7.9 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.6 GAX27872.1 - 1.6e-06 27.7 8.9 9.9 6.5 0.1 7.1 6 0 0 6 6 6 3 Leucine Rich repeat AKAP7_NLS PF10469.9 GAX27874.1 - 2.5e-06 27.6 0.1 6e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain SATase_N PF06426.14 GAX27875.1 - 6.3e-36 122.9 1.1 8e-36 122.6 0.1 1.7 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 GAX27875.1 - 2.6e-12 45.9 7.0 1.6e-08 34.0 0.6 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAX27875.1 - 7.8e-05 22.3 2.9 7.8e-05 22.3 2.9 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Beach PF02138.18 GAX27876.1 - 1.1e-112 376.0 0.0 1.7e-112 375.3 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAX27876.1 - 2.9e-09 36.9 2.0 4.4e-09 36.3 0.3 2.3 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAX27876.1 - 1.7e-05 25.0 0.2 4.4e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 GAX27876.1 - 0.0029 18.4 10.6 0.2 12.6 0.1 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Arm PF00514.23 GAX27876.1 - 0.074 13.1 0.1 1.3 9.2 0.1 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF4800 PF16057.5 GAX27876.1 - 0.077 12.3 0.2 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Trigger_N PF05697.13 GAX27877.1 - 4.8e-21 75.6 0.0 4.8e-21 75.6 0.0 3.7 2 1 1 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 GAX27877.1 - 2.2e-08 34.3 8.2 2.2e-08 34.3 8.2 2.4 1 1 1 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 GAX27877.1 - 1.1e-07 32.1 0.1 4.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase POTRA PF07244.15 GAX27877.1 - 0.014 15.9 4.6 1.6 9.4 0.0 4.4 5 1 0 5 5 5 0 Surface antigen variable number repeat Sucrose_synth PF00862.19 GAX27877.1 - 0.068 11.5 2.6 0.1 10.9 2.6 1.3 1 0 0 1 1 1 0 Sucrose synthase EIIBC-GUT_C PF07663.11 GAX27877.1 - 0.11 12.7 0.0 4.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II C-terminus TINF2_N PF14973.6 GAX27877.1 - 1.5 9.2 5.2 4.5 7.6 2.1 2.5 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF2018 PF09442.10 GAX27877.1 - 1.6 9.7 5.2 1.2 10.1 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) SurA_N_2 PF13623.6 GAX27877.1 - 7.2 6.5 9.3 3.7 7.4 4.4 2.7 1 1 2 3 3 3 0 SurA N-terminal domain fn3 PF00041.21 GAX27878.1 - 0.00049 20.4 2.0 52 4.3 0.0 6.7 7 0 0 7 7 7 1 Fibronectin type III domain Catalase-rel PF06628.12 GAX27879.1 - 0.0018 18.5 3.1 92 3.4 0.0 7.5 8 1 1 9 9 9 0 Catalase-related immune-responsive DUF3350 PF11830.8 GAX27879.1 - 2.7 8.4 7.7 54 4.2 0.1 5.1 6 0 0 6 6 6 0 Domain of unknown function (DUF3350) SelB-wing_2 PF09106.11 GAX27879.1 - 3.6 7.9 21.1 76 3.6 0.1 8.4 10 0 0 10 10 10 0 Elongation factor SelB, winged helix UbiA PF01040.18 GAX27880.1 - 7.8e-51 172.8 17.0 1e-50 172.4 17.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family LRR_6 PF13516.6 GAX27881.1 - 2.8e-49 161.0 42.0 0.0001 22.0 0.1 17.0 18 0 0 18 18 18 12 Leucine Rich repeat LRR_4 PF12799.7 GAX27881.1 - 1e-19 70.3 38.0 0.00056 20.3 0.4 11.2 9 3 0 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX27881.1 - 4.2e-14 50.9 28.3 7.6 7.5 0.1 16.0 17 1 0 17 17 17 3 Leucine Rich Repeat LRR_8 PF13855.6 GAX27881.1 - 1.6e-10 40.6 47.8 0.0017 18.1 0.8 11.2 7 5 0 8 8 8 5 Leucine rich repeat LRR_9 PF14580.6 GAX27881.1 - 0.026 14.0 5.5 0.21 11.1 0.1 3.9 3 1 1 5 5 5 0 Leucine-rich repeat DUF1415 PF07209.12 GAX27882.1 - 7e-11 42.2 0.0 1.3e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1415) RusA PF05866.11 GAX27884.1 - 3.9e-14 53.3 0.0 5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA DUF2520 PF10728.9 GAX27884.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) DEAD PF00270.29 GAX27885.1 - 4.5e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX27885.1 - 0.062 13.6 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain LRR_8 PF13855.6 GAX27886.1 - 2.9e-28 97.4 38.7 3.7e-08 33.0 0.6 6.6 3 2 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 GAX27886.1 - 2.9e-23 81.6 39.9 3.6e-05 24.1 0.6 8.4 2 2 9 12 12 12 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX27886.1 - 7.8e-10 37.9 23.6 1.1 10.0 0.0 11.9 14 0 0 14 14 14 3 Leucine Rich Repeat LRR_2 PF07723.13 GAX27886.1 - 0.0024 18.4 1.4 51 4.8 0.0 5.8 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 GAX27886.1 - 0.0027 17.2 7.1 0.32 10.5 0.1 3.4 1 1 0 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 GAX27886.1 - 0.018 15.1 32.7 0.16 12.1 0.1 9.7 11 0 0 11 11 11 0 Leucine Rich repeat DUF4131 PF13567.6 GAX27886.1 - 0.091 12.4 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 GAX27886.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) AAA_33 PF13671.6 GAX27887.1 - 1.6e-14 54.3 0.0 1.1e-11 45.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAX27887.1 - 2.5e-06 28.1 0.1 0.00013 22.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX27887.1 - 4.9e-05 22.7 0.0 7.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin tRNA_lig_kinase PF08303.11 GAX27887.1 - 0.00021 21.4 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain KTI12 PF08433.10 GAX27887.1 - 0.0013 18.3 0.2 0.085 12.3 0.1 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 GAX27887.1 - 0.0032 17.7 0.0 0.0047 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAX27887.1 - 0.0053 17.2 0.2 0.059 13.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX27887.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GAX27887.1 - 0.02 15.4 0.0 0.05 14.1 0.0 1.5 1 1 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 GAX27887.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI 6PF2K PF01591.18 GAX27887.1 - 0.032 13.5 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_5 PF07728.14 GAX27887.1 - 0.034 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 GAX27887.1 - 0.034 13.8 0.0 7.4 6.2 0.0 2.6 2 1 0 2 2 2 0 Thymidylate kinase APS_kinase PF01583.20 GAX27887.1 - 0.046 13.6 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CPT PF07931.12 GAX27887.1 - 0.058 13.2 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 GAX27887.1 - 0.095 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain dNK PF01712.19 GAX27887.1 - 0.1 12.5 0.1 2.7 7.8 0.0 2.1 1 1 1 2 2 2 0 Deoxynucleoside kinase AAA_14 PF13173.6 GAX27887.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GAX27887.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arf PF00025.21 GAX27887.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Sigma54_activat PF00158.26 GAX27887.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 GAX27887.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 GAX27887.1 - 0.2 11.9 0.0 0.64 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX27887.1 - 0.23 11.6 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 GAX27887.1 - 0.28 10.8 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MeaB PF03308.16 GAX27887.1 - 0.3 10.0 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Beta_helix PF13229.6 GAX27888.1 - 1.4e-10 41.2 7.7 5.5e-10 39.3 7.7 2.0 1 1 0 1 1 1 1 Right handed beta helix region DUF1565 PF07602.11 GAX27888.1 - 0.00062 19.2 2.4 0.01 15.2 1.6 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1565) GSHPx PF00255.19 GAX27889.1 - 1.4e-33 114.7 1.0 2.4e-33 113.9 0.1 1.9 2 0 0 2 2 2 1 Glutathione peroxidase ShK PF01549.24 GAX27889.1 - 1.3e-05 25.6 2.3 1.3e-05 25.6 2.3 1.6 2 0 0 2 2 2 1 ShK domain-like AhpC-TSA PF00578.21 GAX27889.1 - 0.0021 18.0 0.0 0.0031 17.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Methyltransf_21 PF05050.12 GAX27890.1 - 3.7e-10 40.1 0.0 5.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 GAX27890.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_21 PF05050.12 GAX27891.1 - 1.2e-09 38.4 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 GAX27891.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PseudoU_synth_1 PF01416.20 GAX27892.1 - 6.4e-27 94.2 0.0 3.9e-17 62.7 0.0 3.3 2 2 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.32 GAX27893.1 - 2.9e-06 27.9 4.6 0.55 11.2 0.0 6.7 8 1 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX27893.1 - 3.1e-06 27.4 0.0 0.75 10.1 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX27893.1 - 0.034 14.6 1.7 4.3 7.9 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.21 GAX27893.1 - 0.051 13.5 0.8 12 6.0 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat BTB_2 PF02214.22 GAX27894.1 - 6.5e-08 32.8 0.0 2.2e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain CC190 PF15768.5 GAX27894.1 - 0.68 9.9 2.1 1.1 9.3 2.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 FAD_binding_8 PF08022.12 GAX27896.1 - 1.5e-20 73.3 0.0 4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 GAX27896.1 - 7.8e-18 64.8 5.9 2e-17 63.4 5.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAX27896.1 - 2.5e-13 50.5 0.0 1.3e-06 28.6 0.0 2.6 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 GAX27896.1 - 0.0014 18.9 0.0 0.0047 17.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain SQS_PSY PF00494.19 GAX27897.1 - 2.8e-37 128.7 0.0 4.7e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.28 GAX27897.1 - 5.1e-18 65.4 0.0 1e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Vinculin PF01044.19 GAX27897.1 - 0.2 9.8 0.0 0.32 9.2 0.0 1.2 1 0 0 1 1 1 0 Vinculin family BCDHK_Adom3 PF10436.9 GAX27898.1 - 6.8e-41 139.8 0.2 8.8e-41 139.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAX27898.1 - 1.3e-11 44.9 0.0 2.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX27898.1 - 0.0047 16.8 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3775 PF12616.8 GAX27898.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) RRM_1 PF00076.22 GAX27900.1 - 3.7e-71 234.9 0.1 5.9e-21 74.1 0.0 6.0 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAX27900.1 - 0.0002 21.4 0.1 2.6 8.2 0.0 4.7 4 0 0 4 4 4 1 Limkain b1 RRM_5 PF13893.6 GAX27900.1 - 0.00052 19.6 0.0 0.042 13.5 0.0 3.6 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAX27900.1 - 0.0008 19.2 0.0 5.6 6.9 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif BRAP2 PF07576.12 GAX27900.1 - 0.0068 16.6 0.1 0.38 11.0 0.0 2.9 3 0 0 3 3 3 1 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 GAX27900.1 - 0.019 15.0 0.0 1 9.4 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 GAX27900.1 - 0.16 11.6 0.5 12 5.6 0.0 3.4 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Rcd1 PF04078.13 GAX27902.1 - 5.2e-126 419.2 0.6 5.9e-126 419.1 0.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.25 GAX27903.1 - 9e-41 140.0 0.0 3.1e-40 138.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX27903.1 - 6.6e-22 78.0 0.0 5.7e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX27903.1 - 0.00061 19.2 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GAX27903.1 - 0.0047 16.6 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAX27903.1 - 0.0065 16.4 1.6 0.08 12.9 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family DSS1_SEM1 PF05160.13 GAX27903.1 - 1.5 9.0 7.0 3.6 7.7 7.0 1.6 1 0 0 1 1 1 0 DSS1/SEM1 family Vfa1 PF08432.10 GAX27903.1 - 1.5 9.1 6.4 2.7 8.3 6.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PNISR PF15996.5 GAX27903.1 - 6.1 7.1 9.6 9.8 6.4 9.6 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR zf-CHCC PF10276.9 GAX27904.1 - 5.1e-13 48.8 0.8 7.4e-13 48.3 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain DUF150_C PF17384.2 GAX27905.1 - 1.7e-05 24.8 0.0 5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 RimP C-terminal SH3 domain LRR_8 PF13855.6 GAX27906.1 - 2.7e-13 49.4 17.7 2.4e-05 24.0 7.6 5.2 3 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 GAX27906.1 - 4.1e-13 49.3 23.5 1.8e-05 25.0 4.0 6.7 4 1 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX27906.1 - 9.6e-08 31.6 8.9 0.05 14.2 0.5 6.8 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX27906.1 - 0.039 14.0 20.7 0.44 10.7 0.6 5.9 6 0 0 6 6 6 0 Leucine Rich repeat PA28_beta PF02252.18 GAX27907.1 - 5.3e-21 74.8 0.1 4.2e-16 58.9 0.0 2.5 3 0 0 3 3 3 2 Proteasome activator pa28 beta subunit SnoaL_3 PF13474.6 GAX27907.1 - 0.034 14.4 0.2 0.074 13.3 0.2 1.6 1 0 0 1 1 1 0 SnoaL-like domain RepB_primase PF16793.5 GAX27907.1 - 0.037 14.2 2.8 0.084 13.0 0.3 2.0 2 0 0 2 2 2 0 RepB DNA-primase from phage plasmid DASH_Dad2 PF08654.10 GAX27907.1 - 0.045 14.2 1.4 9.6 6.7 0.8 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad2 SNARE PF05739.19 GAX27907.1 - 0.056 13.5 1.8 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 SNARE domain Topoisom_I PF01028.20 GAX27908.1 - 0.052 12.8 0.2 0.065 12.5 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Pro_isomerase PF00160.21 GAX27909.1 - 0.00011 22.5 0.0 0.00018 21.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CENP-H PF05837.12 GAX27909.1 - 1.3 9.5 4.6 2 8.9 4.6 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PDZ PF00595.24 GAX27910.1 - 0.0095 16.3 0.1 0.018 15.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX27910.1 - 0.023 14.6 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.25 GAX27911.1 - 1.8e-63 214.4 0.0 2.2e-62 210.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX27911.1 - 6.6e-32 110.8 0.0 4.6e-25 88.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAX27911.1 - 5.8e-07 28.8 0.0 8.8e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAX27911.1 - 0.0022 18.0 0.2 0.036 14.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAX27911.1 - 0.015 14.9 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 GAX27911.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 GAX27914.1 - 3.1e-07 31.0 0.8 0.0035 18.1 0.3 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX27914.1 - 0.0026 18.0 0.1 0.042 14.1 0.1 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX27914.1 - 0.0032 16.5 0.4 0.043 12.8 0.0 2.6 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FHA PF00498.26 GAX27915.1 - 4.9e-16 58.8 0.1 1.1e-15 57.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAX27915.1 - 3e-05 24.2 0.0 6.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain BT1 PF03092.16 GAX27917.1 - 8.2e-41 139.8 13.6 7.1e-24 83.9 8.2 3.1 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 GAX27917.1 - 6.5e-06 25.4 0.4 2.5e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 PUCC protein polyprenyl_synt PF00348.17 GAX27919.1 - 8e-64 215.1 0.0 1e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase PGM_PMM_I PF02878.16 GAX27920.1 - 2.1e-30 105.3 0.0 3.6e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 GAX27920.1 - 2.1e-22 79.7 0.0 5.2e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAX27920.1 - 3.2e-14 53.1 0.0 7.2e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 GAX27920.1 - 0.00016 21.7 0.0 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pox_D5 PF03288.16 GAX27920.1 - 0.056 13.9 0.0 0.5 10.9 0.0 2.4 2 0 0 2 2 2 0 Poxvirus D5 protein-like ClpS PF02617.17 GAX27921.1 - 6e-14 51.6 0.3 9.1e-14 51.0 0.3 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-trcl PF13451.6 GAX27922.1 - 0.028 14.3 0.8 0.063 13.2 0.8 1.6 1 0 0 1 1 1 0 Probable zinc-ribbon domain Synaptobrevin PF00957.21 GAX27923.1 - 1.2e-25 89.1 3.1 2.1e-25 88.3 3.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAX27923.1 - 7.8e-05 22.6 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1860 PF08949.10 GAX27923.1 - 0.018 14.8 1.0 0.022 14.5 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) Fzo_mitofusin PF04799.13 GAX27923.1 - 0.037 13.6 2.3 0.061 12.9 2.3 1.4 1 0 0 1 1 1 0 fzo-like conserved region DHR10 PF18595.1 GAX27923.1 - 0.11 12.6 5.6 0.28 11.3 5.6 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Orf78 PF06024.12 GAX27923.1 - 0.14 12.4 1.4 0.3 11.4 1.4 1.6 1 1 0 1 1 1 0 Orf78 (ac78) Utp14 PF04615.13 GAX27924.1 - 5.6e-137 458.4 69.8 5.6e-137 458.4 69.8 1.5 1 1 0 1 1 1 1 Utp14 protein Cation_ATPase PF13246.6 GAX27924.1 - 0.057 13.5 0.5 0.23 11.5 0.5 2.0 1 0 0 1 1 1 0 Cation transport ATPase (P-type) 3HCDH_N PF02737.18 GAX27925.1 - 7.6e-52 175.8 0.1 1.9e-51 174.5 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 GAX27925.1 - 1.4e-40 139.2 0.0 2.4e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 GAX27925.1 - 4.2e-31 107.4 0.1 1.5e-23 83.3 0.0 3.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 GAX27925.1 - 7.7e-19 68.4 0.0 2.6e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase RelE PF06296.12 GAX27925.1 - 0.031 14.4 0.0 0.12 12.5 0.0 2.0 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system DUF2812 PF11193.8 GAX27925.1 - 0.12 12.6 0.1 0.51 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) Sacchrp_dh_NADP PF03435.18 GAX27925.1 - 0.16 12.3 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Toprim_N PF08275.11 GAX27926.1 - 2.6e-23 82.5 0.0 1.4e-21 76.9 0.0 2.6 1 1 0 1 1 1 1 DNA primase catalytic core, N-terminal domain Toprim_2 PF13155.6 GAX27926.1 - 4.1e-13 49.6 0.0 1.2e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 GAX27926.1 - 1.7e-11 44.5 0.0 5.2e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Dehydratase_MU PF02288.15 GAX27926.1 - 0.086 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Dehydratase medium subunit Toprim PF01751.22 GAX27926.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Toprim domain LON_substr_bdg PF02190.16 GAX27927.1 - 0.0016 18.4 3.5 0.01 15.7 0.1 2.8 3 1 0 3 3 3 2 ATP-dependent protease La (LON) substrate-binding domain Ank_3 PF13606.6 GAX27928.1 - 0.00012 22.2 0.0 0.00039 20.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 GAX27928.1 - 0.00022 21.7 0.0 0.00046 20.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX27928.1 - 0.00024 21.6 0.0 0.00064 20.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX27928.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) GTP-bdg_N PF13167.6 GAX27929.1 - 2e-30 105.3 0.1 4.8e-30 104.1 0.1 1.7 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 GAX27929.1 - 2.8e-29 101.5 2.4 5.5e-29 100.6 2.4 1.5 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 GAX27929.1 - 7.4e-21 74.4 0.0 1.9e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX27929.1 - 5.2e-07 29.7 1.3 0.032 14.1 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAX27929.1 - 1.2e-05 24.9 0.3 2.9e-05 23.7 0.3 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX27929.1 - 0.00013 22.0 0.9 0.027 14.6 0.0 2.9 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 GAX27929.1 - 0.0014 18.2 0.3 0.022 14.3 0.4 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 GAX27929.1 - 0.0024 17.5 1.5 0.069 12.7 0.2 2.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 GAX27929.1 - 0.0056 16.1 0.4 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 GAX27929.1 - 0.016 15.2 0.1 0.063 13.3 0.1 2.1 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ras PF00071.22 GAX27929.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Ras family HOOK PF05622.12 GAX27929.1 - 0.48 8.5 4.6 0.91 7.6 0.1 2.6 2 1 1 3 3 3 0 HOOK protein FA_hydroxylase PF04116.13 GAX27930.1 - 1.8e-18 67.2 10.6 1.8e-18 67.2 10.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NAD_binding_10 PF13460.6 GAX27931.1 - 2.9e-10 40.4 0.1 5.8e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAX27931.1 - 4.3e-08 32.9 0.3 6.2e-08 32.4 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAX27931.1 - 0.00011 21.4 0.2 0.00015 21.0 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 GAX27931.1 - 0.00083 19.0 3.0 0.0028 17.2 3.0 1.8 1 1 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.19 GAX27931.1 - 0.0044 16.4 0.2 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAX27931.1 - 0.0051 16.3 0.1 0.007 15.8 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 GAX27931.1 - 0.033 14.8 0.2 0.1 13.2 0.2 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 GAX27931.1 - 0.038 13.4 0.2 0.064 12.7 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 GAX27931.1 - 0.041 12.9 0.2 0.065 12.2 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 GAX27931.1 - 0.13 12.5 0.8 0.29 11.4 0.8 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Asparaginase_C PF17763.1 GAX27931.1 - 0.51 10.6 4.2 1.3 9.3 0.4 2.8 2 1 1 3 3 3 0 Glutaminase/Asparaginase C-terminal domain HA PF03457.14 GAX27932.1 - 4.1e-48 161.6 10.9 2.2e-21 75.9 2.7 3.2 3 0 0 3 3 3 3 Helicase associated domain DUF2153 PF09921.9 GAX27932.1 - 0.074 12.9 0.9 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) NAD_binding_6 PF08030.12 GAX27932.1 - 0.22 11.6 0.5 0.76 9.9 0.3 1.9 1 1 0 1 1 1 0 Ferric reductase NAD binding domain SAPS PF04499.15 GAX27932.1 - 0.46 9.2 4.5 0.22 10.2 0.1 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PROCN PF08083.11 GAX27933.1 - 2.6e-230 764.2 8.7 3.7e-230 763.7 8.7 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 GAX27933.1 - 1.9e-128 426.8 0.4 3.3e-128 426.1 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 GAX27933.1 - 2.6e-87 290.7 2.6 7.5e-87 289.2 2.6 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 GAX27933.1 - 1.1e-75 252.7 1.9 3.8e-75 251.0 1.9 2.0 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 GAX27933.1 - 4.7e-71 237.1 0.0 9.6e-71 236.1 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 GAX27933.1 - 9.6e-48 160.5 0.2 2.8e-47 159.0 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 GAX27933.1 - 5.6e-44 149.0 0.0 1.5e-43 147.7 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 GAX27933.1 - 0.00076 19.4 0.0 0.0025 17.8 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HEAT_2 PF13646.6 GAX27934.1 - 6.5e-05 23.2 0.2 0.1 13.0 0.0 4.0 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 GAX27934.1 - 0.00013 21.9 1.2 1.3 9.5 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 GAX27934.1 - 0.00033 20.7 2.1 0.00077 19.5 1.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 GAX27934.1 - 0.0084 15.9 5.3 0.52 10.0 0.6 4.1 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 GAX27934.1 - 0.044 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 CLASP N terminal NAD_binding_8 PF13450.6 GAX27935.1 - 2.8e-11 43.5 0.2 6e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX27935.1 - 1.4e-09 37.6 0.3 7.5e-06 25.3 0.1 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 GAX27935.1 - 8.2e-08 32.2 0.0 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAX27935.1 - 5.9e-07 29.1 0.1 0.00019 20.9 0.0 2.7 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAX27935.1 - 0.0005 19.4 0.0 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX27935.1 - 0.00059 19.2 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAX27935.1 - 0.00073 18.8 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAX27935.1 - 0.00095 18.3 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAX27935.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 GAX27935.1 - 0.0032 16.9 0.1 0.17 11.2 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase HI0933_like PF03486.14 GAX27935.1 - 0.0068 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAX27935.1 - 0.048 12.9 0.1 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.26 GAX27936.1 - 1.3e-23 83.6 0.1 4.4e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAX27936.1 - 6.2e-15 55.3 0.0 2.3e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAX27936.1 - 5.4e-08 32.8 0.3 1.2e-05 25.3 0.0 2.9 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain NAD_binding_8 PF13450.6 GAX27938.1 - 1.6e-10 41.1 0.1 4.5e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX27938.1 - 3.5e-08 33.4 2.0 2.9e-07 30.4 2.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAX27938.1 - 7.4e-08 32.1 0.0 1.5e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAX27938.1 - 0.0023 17.2 1.3 0.38 9.9 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAX27938.1 - 0.0033 16.7 0.1 0.0057 15.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAX27938.1 - 0.0063 15.6 0.6 0.011 14.8 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAX27938.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX27938.1 - 0.056 12.1 0.9 0.081 11.6 0.3 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 GAX27938.1 - 0.083 13.5 0.4 6.2 7.5 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX27938.1 - 0.087 11.9 0.2 0.17 10.9 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAX27938.1 - 0.18 11.8 0.4 0.33 10.9 0.4 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding SQS_PSY PF00494.19 GAX27940.1 - 0.34 10.4 2.5 0.55 9.7 2.5 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase SNARE PF05739.19 GAX27940.1 - 1.5 8.9 11.6 4.9 7.2 0.2 3.8 3 1 1 4 4 4 0 SNARE domain DUF4606 PF15379.6 GAX27940.1 - 3 8.1 8.8 0.19 12.0 2.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4606) Lectin_N PF03954.14 GAX27940.1 - 4.2 7.1 6.3 4.9 6.9 2.3 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF2120 PF09893.9 GAX27940.1 - 4.3 7.4 19.5 2.7 8.1 15.1 2.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Arc_PepC_II PF06847.11 GAX27940.1 - 6.2 7.4 7.8 0.84 10.2 0.8 2.6 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II TPR_1 PF00515.28 GAX27941.1 - 4e-21 73.9 30.1 8.1e-05 22.3 0.1 7.5 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAX27941.1 - 1.4e-17 62.8 25.0 0.009 16.8 0.0 9.7 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAX27941.1 - 1.1e-16 59.5 44.5 0.00011 22.0 0.2 9.7 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAX27941.1 - 1.2e-16 60.9 20.4 0.03 14.8 0.1 7.6 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX27941.1 - 4.2e-16 57.8 26.6 3.4e-05 23.7 0.0 7.5 9 0 0 9 9 6 4 Tetratricopeptide repeat ANAPC8 PF04049.13 GAX27941.1 - 1.8e-13 50.7 0.0 5e-11 42.8 0.0 3.0 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.6 GAX27941.1 - 4.5e-13 48.6 15.8 1.2e-07 31.2 0.1 6.4 4 3 3 7 7 7 4 TPR repeat TPR_17 PF13431.6 GAX27941.1 - 2.7e-12 46.1 13.9 0.017 15.5 0.1 8.9 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX27941.1 - 1.1e-10 40.8 19.3 0.0058 16.6 0.1 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAX27941.1 - 7.7e-08 32.9 37.6 0.00082 20.0 0.2 8.7 7 2 3 10 10 8 2 Tetratricopeptide repeat ChAPs PF09295.10 GAX27941.1 - 5.7e-06 25.6 0.8 7.7e-05 21.9 0.1 2.6 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 GAX27941.1 - 2.5e-05 24.5 38.3 3.3e-05 24.1 3.9 7.5 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX27941.1 - 0.00012 22.5 32.5 6.7 7.6 0.1 9.4 9 1 0 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX27941.1 - 0.00079 19.6 17.6 3.2 8.0 0.9 5.7 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 GAX27941.1 - 0.0087 15.8 8.4 0.7 9.6 0.9 4.3 2 2 2 4 4 4 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GAX27941.1 - 0.037 14.2 19.0 0.27 11.4 2.5 5.1 5 1 1 7 7 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX27941.1 - 0.11 12.6 5.1 1.1 9.3 0.0 3.8 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat CCP_MauG PF03150.14 GAX27941.1 - 0.12 13.0 3.0 0.64 10.7 0.2 3.1 4 0 0 4 4 3 0 Di-haem cytochrome c peroxidase BTAD PF03704.17 GAX27941.1 - 0.14 12.6 8.9 1.1 9.7 1.2 3.7 2 1 0 3 3 3 0 Bacterial transcriptional activator domain DUF2225 PF09986.9 GAX27941.1 - 0.2 11.3 6.0 0.17 11.6 0.3 2.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.12 GAX27941.1 - 0.38 11.5 0.0 0.38 11.5 0.0 3.7 5 0 0 5 5 2 0 Sel1 repeat TPR_20 PF14561.6 GAX27941.1 - 0.84 10.0 10.8 2.9 8.3 0.6 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAX27941.1 - 1.6 8.8 4.8 1.5 8.8 0.3 2.9 2 1 1 3 3 2 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 GAX27941.1 - 1.7 8.6 26.6 1.3 9.0 0.3 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat PEPCK_N PF17297.2 GAX27943.1 - 0.034 13.8 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain Homeobox_KN PF05920.11 GAX27944.1 - 2.1e-10 40.3 0.3 6.4e-10 38.8 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAX27944.1 - 0.005 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain CDC37_M PF08565.11 GAX27945.1 - 1.5e-22 79.7 3.1 1.5e-22 79.7 3.1 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 GAX27945.1 - 5.3e-12 45.7 0.0 5.3e-12 45.7 0.0 3.2 2 2 1 3 3 3 1 Cdc37 C terminal domain CDC37_N PF03234.14 GAX27945.1 - 1.1e-11 45.7 23.1 1.1e-11 45.7 23.1 3.0 2 2 0 2 2 2 1 Cdc37 N terminal kinase binding Cwf_Cwc_15 PF04889.12 GAX27945.1 - 0.0065 16.2 21.7 0.0065 16.2 21.7 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF4763 PF15960.5 GAX27945.1 - 0.0072 15.7 11.0 0.016 14.5 11.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) DUF3573 PF12097.8 GAX27945.1 - 0.98 8.2 2.5 1.9 7.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) AAA_2 PF07724.14 GAX27947.1 - 1.7e-40 138.9 0.0 6.1e-39 133.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAX27947.1 - 6e-31 106.5 2.2 6e-31 106.5 2.2 2.8 3 0 0 3 3 2 1 AAA lid domain ClpB_D2-small PF10431.9 GAX27947.1 - 4.9e-19 68.2 0.0 2e-18 66.2 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GAX27947.1 - 5.9e-17 62.3 0.0 8.6e-11 42.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX27947.1 - 7.2e-09 35.8 0.1 0.0031 17.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX27947.1 - 1.1e-08 35.6 0.6 1.1e-06 29.1 0.3 3.8 3 1 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 GAX27947.1 - 5.1e-07 29.8 0.0 0.051 13.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain TniB PF05621.11 GAX27947.1 - 5.3e-07 29.2 0.0 0.00023 20.6 0.0 2.8 1 1 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 GAX27947.1 - 2.5e-06 27.8 0.2 0.002 18.4 0.0 3.8 2 2 0 2 2 2 1 AAA domain Clp_N PF02861.20 GAX27947.1 - 7.8e-06 25.9 2.0 0.011 15.9 0.0 4.0 4 0 0 4 4 4 1 Clp amino terminal domain, pathogenicity island component ATPase_2 PF01637.18 GAX27947.1 - 2.9e-05 24.1 0.9 0.46 10.3 0.0 4.0 2 2 1 4 4 4 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAX27947.1 - 9e-05 22.8 0.1 1.5 9.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 GAX27947.1 - 0.00016 21.5 0.0 0.088 12.5 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 GAX27947.1 - 0.0013 18.5 0.1 0.36 10.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 GAX27947.1 - 0.0017 18.2 0.0 0.075 12.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 GAX27947.1 - 0.0033 17.6 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 GAX27947.1 - 0.0034 16.7 0.0 1.6 8.0 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 GAX27947.1 - 0.0041 16.7 0.0 0.23 11.0 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_19 PF13245.6 GAX27947.1 - 0.014 15.7 0.2 0.13 12.6 0.2 2.6 1 1 0 1 1 1 0 AAA domain Ran-binding PF05508.11 GAX27947.1 - 0.035 13.1 0.3 0.073 12.0 0.3 1.4 1 0 0 1 1 1 0 RanGTP-binding protein TsaE PF02367.17 GAX27947.1 - 0.04 13.9 0.0 0.65 10.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 GAX27947.1 - 0.09 12.3 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 GAX27947.1 - 0.24 9.2 2.2 0.44 8.4 2.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.6 GAX27947.1 - 0.9 9.3 3.9 2.7 7.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain YlqD PF11068.8 GAX27947.1 - 2.1 8.7 9.3 1.9 8.8 4.1 2.5 1 1 1 2 2 2 0 YlqD protein EMC3_TMCO1 PF01956.16 GAX27950.1 - 1.2 8.9 2.5 15 5.3 0.6 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like FTA4 PF13093.6 GAX27951.1 - 0.22 11.4 2.7 0.39 10.6 1.2 1.9 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MutS_IV PF05190.18 GAX27951.1 - 1.6 9.1 5.5 1.9 8.9 0.3 2.7 2 1 1 3 3 3 0 MutS family domain IV AAA_2 PF07724.14 GAX27952.1 - 5e-51 173.2 0.0 9.4e-49 165.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAX27952.1 - 6e-34 116.1 2.3 6e-34 116.1 2.3 3.2 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 GAX27952.1 - 3.7e-25 88.9 0.0 2.3e-13 50.7 0.0 3.2 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAX27952.1 - 1.3e-17 63.6 0.0 7.6e-17 61.1 0.0 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAX27952.1 - 3.1e-16 59.6 2.0 7.6e-10 38.9 0.0 4.0 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 GAX27952.1 - 2.5e-11 43.5 2.9 2.7e-05 24.2 0.7 3.6 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 GAX27952.1 - 2.7e-11 44.1 13.4 9.8e-07 29.3 0.1 6.0 4 2 2 6 6 6 2 AAA ATPase domain AAA_22 PF13401.6 GAX27952.1 - 5e-11 43.0 0.5 0.0016 18.7 0.0 4.8 3 2 2 5 5 4 2 AAA domain Sigma54_activat PF00158.26 GAX27952.1 - 4.3e-08 33.0 0.0 2.7e-05 24.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 GAX27952.1 - 8.3e-08 31.9 0.1 0.00026 20.5 0.1 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 GAX27952.1 - 1.7e-07 31.4 0.0 0.0077 16.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAX27952.1 - 2.4e-07 30.4 0.0 0.011 15.3 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAX27952.1 - 1.2e-06 28.4 0.0 0.0055 16.4 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 GAX27952.1 - 1.5e-06 28.5 0.2 0.026 14.8 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAX27952.1 - 5.6e-06 26.2 0.2 0.0024 17.6 0.2 3.4 3 1 1 4 4 3 1 AAA domain AAA_18 PF13238.6 GAX27952.1 - 2.5e-05 24.8 0.2 0.74 10.4 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_3 PF07726.11 GAX27952.1 - 5.5e-05 23.0 0.0 0.0095 15.8 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 GAX27952.1 - 0.00013 22.2 0.0 0.62 10.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 GAX27952.1 - 0.00014 21.9 6.7 0.69 9.8 0.1 4.6 3 2 1 5 5 4 2 ATPase domain predominantly from Archaea AAA_21 PF13304.6 GAX27952.1 - 0.0002 21.3 0.1 2.7 7.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAX27952.1 - 0.00035 20.2 0.9 0.0034 17.0 0.1 2.8 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 GAX27952.1 - 0.0004 20.4 0.0 0.46 10.5 0.0 3.0 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAX27952.1 - 0.00041 19.8 0.1 2.9 7.2 0.0 3.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX27952.1 - 0.00043 20.4 0.5 2.7 8.1 0.0 3.8 4 0 0 4 4 2 2 AAA domain NACHT PF05729.12 GAX27952.1 - 0.00048 20.1 0.0 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 GAX27952.1 - 0.00048 19.9 1.1 2.5 7.8 0.0 4.0 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAX27952.1 - 0.00054 20.3 0.0 2.7 8.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase DUF815 PF05673.13 GAX27952.1 - 0.00059 19.1 0.0 0.15 11.2 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAX27952.1 - 0.00092 19.7 1.8 2.4 8.7 0.0 3.8 3 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 GAX27952.1 - 0.0013 18.7 0.1 2.6 7.9 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase Zeta_toxin PF06414.12 GAX27952.1 - 0.0021 17.4 0.0 1.5 8.0 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 GAX27952.1 - 0.0022 18.3 0.3 0.2 12.0 0.1 3.4 3 1 0 3 3 2 1 AAA domain ResIII PF04851.15 GAX27952.1 - 0.012 15.6 0.0 8 6.4 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 GAX27952.1 - 0.014 14.4 0.0 0.061 12.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 GAX27952.1 - 0.021 14.6 0.2 12 5.8 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain Torsin PF06309.11 GAX27952.1 - 0.022 14.9 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Torsin SpoVR PF04293.13 GAX27952.1 - 0.032 12.9 0.6 0.064 11.9 0.6 1.4 1 0 0 1 1 1 0 SpoVR like protein AAA_24 PF13479.6 GAX27952.1 - 0.043 13.6 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAX27952.1 - 0.054 12.7 0.0 5.9 6.0 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain PmbA_TldD PF01523.16 GAX27952.1 - 0.061 13.1 2.7 0.08 12.8 0.5 2.5 2 1 0 2 2 2 0 Putative modulator of DNA gyrase APC_N_CC PF16689.5 GAX27952.1 - 0.068 13.3 1.5 0.24 11.5 1.5 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain BLACT_WH PF17778.1 GAX27952.1 - 0.09 12.8 1.4 0.66 10.0 0.1 2.7 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Ran-binding PF05508.11 GAX27952.1 - 0.11 11.4 4.7 0.048 12.6 1.3 2.0 2 0 0 2 2 2 0 RanGTP-binding protein MMR_HSR1 PF01926.23 GAX27952.1 - 0.15 12.2 0.0 22 5.1 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 GAX27952.1 - 0.32 11.1 0.0 0.32 11.1 0.0 3.5 3 1 0 3 3 2 0 Helicase HerA, central domain YlqD PF11068.8 GAX27952.1 - 0.4 11.0 12.0 0.18 12.2 6.3 2.4 1 1 1 2 2 2 0 YlqD protein CorA PF01544.18 GAX27952.1 - 0.41 9.9 3.7 0.95 8.7 3.7 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Spc7 PF08317.11 GAX27952.1 - 0.43 9.4 11.7 0.83 8.5 11.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein V-SNARE PF05008.15 GAX27952.1 - 0.53 10.7 6.0 0.87 10.0 4.2 2.4 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus AAA_11 PF13086.6 GAX27952.1 - 1.5 8.5 8.7 2.9 7.6 0.0 3.6 3 1 0 3 3 2 0 AAA domain AAA_23 PF13476.6 GAX27952.1 - 3.2 8.2 0.0 3.2 8.2 0.0 4.4 3 2 0 3 3 2 0 AAA domain V_ATPase_I PF01496.19 GAX27952.1 - 5.5 4.8 5.2 8 4.2 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M14 PF00246.24 GAX27954.1 - 7.2e-12 45.7 0.0 1.7e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.8 GAX27954.1 - 0.0077 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 GAX27954.1 - 0.039 13.0 0.3 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family GST_N_3 PF13417.6 GAX27955.1 - 8.4e-07 29.3 0.0 2.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAX27955.1 - 1.4e-05 25.3 0.0 3.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX27955.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAX27955.1 - 0.0046 17.2 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAX27955.1 - 0.0096 15.9 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAX27955.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FKBP_C PF00254.28 GAX27956.1 - 7.3e-25 87.1 0.0 1.1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 GAX27956.1 - 2.2e-06 28.6 0.2 5.5e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase AAA PF00004.29 GAX27957.1 - 3.5e-14 53.3 0.0 8.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX27957.1 - 5e-05 23.8 0.8 0.00036 21.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAX27957.1 - 0.00013 22.3 0.3 0.0014 18.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAX27957.1 - 0.00033 20.7 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAX27957.1 - 0.0023 18.5 0.0 0.84 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAX27957.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAX27957.1 - 0.022 14.9 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAX27957.1 - 0.024 14.3 0.6 0.078 12.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 GAX27957.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 GAX27957.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAX27957.1 - 0.11 13.0 0.9 0.48 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 GAX27957.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 GAX27957.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 GAX27957.1 - 0.16 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAX27957.1 - 0.19 11.7 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain PDZ_6 PF17820.1 GAX27958.1 - 4.4e-11 42.5 0.1 2.9e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 GAX27958.1 - 4.6e-10 39.7 0.0 0.00023 21.4 0.0 2.7 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 GAX27958.1 - 9.5e-09 35.5 0.1 0.00032 21.0 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 GAX27958.1 - 0.0002 21.2 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain PK_C PF02887.16 GAX27958.1 - 0.068 13.4 0.1 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Siva PF05458.12 GAX27958.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) ATP_bind_3 PF01171.20 GAX27959.1 - 2.9e-36 124.9 0.0 5.7e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 PP-loop family DUF924 PF06041.11 GAX27959.1 - 1.7e-13 51.1 4.1 3.2e-13 50.2 4.1 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) NAD_synthase PF02540.17 GAX27959.1 - 8.6e-06 25.0 0.0 2.9e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 GAX27959.1 - 1.5e-05 24.8 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 GAX27959.1 - 2.1e-05 24.1 0.0 0.0044 16.5 0.0 2.3 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAX27959.1 - 0.0014 17.5 0.0 0.004 16.0 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase Glyco_hydro_38N PF01074.22 GAX27959.1 - 0.0071 15.7 3.2 0.015 14.7 3.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain ThiI PF02568.14 GAX27959.1 - 0.19 11.3 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Ribosomal_L24e PF01246.20 GAX27962.1 - 6.2e-18 64.8 5.3 6.2e-18 64.8 5.3 2.6 3 0 0 3 3 3 1 Ribosomal protein L24e Peptidase_M43 PF05572.13 GAX27963.1 - 2.6e-14 53.4 0.1 4.1e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX27963.1 - 0.00074 20.0 0.1 0.0012 19.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX27963.1 - 0.002 18.3 1.4 0.0032 17.6 1.4 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX27963.1 - 0.079 12.6 0.5 0.14 11.8 0.5 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 GAX27964.1 - 8.2e-14 51.8 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX27964.1 - 2e-05 24.8 0.1 3.2e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX27964.1 - 0.00083 19.9 0.4 0.0017 18.8 0.4 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX27964.1 - 0.04 13.6 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF2554 PF10829.8 GAX27964.1 - 0.094 13.1 0.3 0.2 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) Peptidase_M48 PF01435.18 GAX27964.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Peptidase family M48 Reprolysin_2 PF13574.6 GAX27964.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.1 2 1 1 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 GAX27965.1 - 1.1e-13 51.3 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX27965.1 - 0.00068 19.8 0.1 0.0013 18.9 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX27965.1 - 0.0045 16.6 0.0 0.02 14.6 0.0 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX27965.1 - 0.0069 16.9 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CBM_6 PF03422.15 GAX27966.1 - 7.4e-36 123.2 1.3 2.8e-12 47.0 0.0 3.3 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX27966.1 - 1.4e-18 67.4 0.0 1.4e-18 67.4 0.0 2.0 1 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DEAD PF00270.29 GAX27966.1 - 9.1e-18 64.6 0.0 1.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF5010_C PF18099.1 GAX27966.1 - 1.7e-12 47.5 3.3 4.8e-07 29.9 0.0 3.6 3 0 0 3 3 3 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX27966.1 - 1.9e-09 37.8 1.6 0.014 15.6 0.0 3.6 3 0 0 3 3 3 3 Carbohydrate binding module (family 35) ResIII PF04851.15 GAX27966.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Iron_transport PF10634.9 GAX27966.1 - 0.093 12.9 0.1 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Fe2+ transport protein Dynamin_N PF00350.23 GAX27967.1 - 1.6e-21 77.1 0.8 2.2e-11 44.1 0.0 3.0 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 GAX27967.1 - 1.1e-12 48.0 0.0 2.9e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX27967.1 - 6.5e-10 38.9 0.1 5.3e-07 29.4 0.0 3.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAX27967.1 - 5.3e-06 26.4 0.5 0.025 14.5 0.0 3.4 4 0 0 4 4 4 2 RsgA GTPase FeoB_N PF02421.18 GAX27967.1 - 0.0011 18.5 0.0 0.59 9.7 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B ABC_tran PF00005.27 GAX27967.1 - 0.02 15.4 0.1 0.37 11.3 0.0 2.9 3 1 0 3 3 3 0 ABC transporter KAP_NTPase PF07693.14 GAX27967.1 - 0.046 13.0 0.7 0.17 11.1 0.7 1.9 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.17 GAX27967.1 - 0.053 13.3 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 GAX27967.1 - 0.06 12.6 0.0 0.18 11.1 0.0 1.8 1 0 0 1 1 1 0 Septin IIGP PF05049.13 GAX27967.1 - 0.09 11.8 0.0 0.55 9.2 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) RNase_J_C PF17770.1 GAX27967.1 - 0.23 12.5 0.4 14 6.9 0.0 3.8 4 0 0 4 4 3 0 Ribonuclease J C-terminal domain ERp29 PF07749.12 GAX27967.1 - 5.9 7.9 5.6 39 5.2 1.0 3.8 2 2 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain AAA_12 PF13087.6 GAX27969.1 - 3.4e-21 75.8 0.2 1.3e-20 73.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain R3H PF01424.22 GAX27969.1 - 2.3e-05 24.3 0.0 4.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 R3H domain UvrD_C_2 PF13538.6 GAX27969.1 - 0.00058 19.6 0.0 0.0017 18.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MFS_1 PF07690.16 GAX27970.1 - 1.8e-12 46.9 26.8 9e-12 44.6 26.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkr1 PF08636.10 GAX27971.1 - 6.5e-07 29.4 0.6 7.8e-07 29.2 0.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 PRORP PF16953.5 GAX27972.1 - 7e-14 51.9 1.1 7.2e-11 42.1 0.5 3.6 2 1 0 2 2 2 1 Protein-only RNase P PPR_long PF17177.4 GAX27972.1 - 0.00041 19.8 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 GAX27972.1 - 0.083 13.1 0.0 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family PRORP PF16953.5 GAX27973.1 - 1.7e-14 53.9 4.8 8.4e-08 32.0 0.1 4.2 3 1 0 3 3 3 2 Protein-only RNase P RNase_Zc3h12a PF11977.8 GAX27973.1 - 1.5e-06 28.1 0.2 0.00021 21.1 0.0 2.4 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain SEO_N PF14576.6 GAX27973.1 - 0.0057 15.9 0.0 0.09 11.9 0.0 2.6 3 0 0 3 3 3 1 Sieve element occlusion N-terminus PPR_2 PF13041.6 GAX27973.1 - 0.02 15.1 0.0 0.06 13.5 0.0 1.9 1 0 0 1 1 1 0 PPR repeat family TPR_7 PF13176.6 GAX27973.1 - 0.034 14.2 0.2 1.5 9.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5623 PF18536.1 GAX27973.1 - 0.058 13.7 0.3 0.14 12.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) TPR_14 PF13428.6 GAX27973.1 - 0.14 13.1 0.3 25 6.0 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat CLAG PF03805.13 GAX27973.1 - 0.16 9.5 0.1 0.25 8.9 0.1 1.2 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Prefoldin_2 PF01920.20 GAX27974.1 - 4.7e-21 74.7 10.4 5.6e-21 74.5 10.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit Mo25 PF08569.11 GAX27974.1 - 0.003 17.0 0.7 0.012 15.0 0.9 1.8 1 1 0 1 1 1 1 Mo25-like DUF3535 PF12054.8 GAX27974.1 - 0.013 14.8 3.8 0.015 14.6 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) DivIVA PF05103.13 GAX27974.1 - 0.017 15.2 5.1 0.57 10.3 0.4 2.1 2 0 0 2 2 2 0 DivIVA protein APG6_N PF17675.1 GAX27974.1 - 0.031 14.8 10.8 0.035 14.6 1.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 GAX27974.1 - 0.034 14.2 0.5 0.034 14.2 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RUN PF02759.19 GAX27974.1 - 0.043 13.8 0.4 0.091 12.7 0.1 1.6 1 1 0 1 1 1 0 RUN domain DinB_2 PF12867.7 GAX27974.1 - 0.057 13.9 1.0 1.3 9.6 0.1 2.1 1 1 1 2 2 2 0 DinB superfamily Prefoldin PF02996.17 GAX27974.1 - 0.062 13.2 0.8 0.062 13.2 0.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit FerA PF08165.11 GAX27974.1 - 0.067 13.1 0.4 0.067 13.1 0.4 2.3 2 1 0 2 2 2 0 FerA (NUC095) domain RPW8 PF05659.11 GAX27974.1 - 0.13 11.9 2.5 1.4 8.6 0.2 2.2 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FlgN PF05130.12 GAX27974.1 - 0.15 12.6 7.7 0.27 11.7 7.7 1.4 1 1 0 1 1 1 0 FlgN protein Hrs_helical PF12210.8 GAX27974.1 - 0.17 12.4 7.2 0.75 10.4 2.0 2.2 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Med7 PF05983.11 GAX27974.1 - 0.22 11.6 5.0 1.3 9.0 0.1 2.1 1 1 1 2 2 2 0 MED7 protein KfrA_N PF11740.8 GAX27974.1 - 0.35 11.5 7.1 18 6.0 7.1 2.1 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term BBIP10 PF14777.6 GAX27974.1 - 0.36 10.4 4.4 0.32 10.6 1.7 2.2 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 DUF948 PF06103.11 GAX27974.1 - 0.75 10.1 3.3 5.9 7.2 0.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 GAX27974.1 - 0.85 10.3 4.1 1.8 9.2 0.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.14 GAX27974.1 - 1.1 9.6 10.4 0.11 12.8 1.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Csm1_N PF18504.1 GAX27974.1 - 2 8.8 9.9 0.23 11.8 2.0 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain CENP-H PF05837.12 GAX27974.1 - 2.4 8.6 9.0 3.8 7.9 1.6 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 GAX27974.1 - 3 8.5 8.0 3.8e+02 1.8 8.0 2.1 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 GAX27974.1 - 4.8 7.7 14.6 4.9 7.7 3.3 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 GAX27974.1 - 7.4 6.9 9.1 4.7 7.5 1.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF285 PF03382.14 GAX27975.1 - 1.1e-104 344.7 45.8 1e-33 115.7 7.8 2.7 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 PhyH PF05721.13 GAX27976.1 - 0.00029 21.1 0.2 0.00074 19.8 0.2 1.7 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Agenet PF05641.12 GAX27976.1 - 0.0019 18.6 0.0 0.0081 16.6 0.0 2.1 1 0 0 1 1 1 1 Agenet domain DUF4537 PF15057.6 GAX27976.1 - 0.0036 17.3 0.0 0.091 12.8 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4537) Tcp10_C PF07202.13 GAX27976.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 T-complex protein 10 C-terminus PWWP PF00855.17 GAX27976.1 - 0.012 16.0 0.0 0.05 14.0 0.0 2.1 1 0 0 1 1 1 0 PWWP domain Smim3 PF17307.2 GAX27976.1 - 0.019 14.4 0.4 0.056 12.9 0.4 1.7 1 0 0 1 1 1 0 Small integral membrane protein 3 Tudor_2 PF18104.1 GAX27976.1 - 0.13 11.9 0.0 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Rad9_Rad53_bind PF08605.10 GAX27976.1 - 0.16 12.1 0.0 1.6 8.9 0.0 2.4 2 1 0 3 3 3 0 Fungal Rad9-like Rad53-binding DNA_methylase PF00145.17 GAX27977.1 - 7.7e-08 32.1 1.2 9.5e-06 25.2 0.1 3.1 3 1 0 3 3 3 1 C-5 cytosine-specific DNA methylase PGA2 PF07543.12 GAX27977.1 - 0.64 10.0 4.9 0.54 10.2 0.2 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 PP2C PF00481.21 GAX27978.1 - 3.5e-65 220.2 0.2 2e-55 188.2 0.2 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 GAX27978.1 - 8.5e-09 35.6 2.5 2.5e-08 34.1 0.2 2.6 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAX27978.1 - 5.9e-06 26.1 0.0 0.015 14.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C tRNA-synt_2 PF00152.20 GAX27979.1 - 3.1e-75 253.2 0.0 4.7e-75 252.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 GAX27979.1 - 1e-09 38.4 1.7 2.7e-09 37.0 1.7 1.8 1 0 0 1 1 1 1 WHEP-TRS domain tRNA_anti-codon PF01336.25 GAX27979.1 - 4.8e-06 26.5 0.1 8.5e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAX27979.1 - 0.017 14.6 0.1 1.8 8.0 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) DUF3408 PF11888.8 GAX27979.1 - 0.043 13.9 6.2 0.081 13.1 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) TP53IP5 PF15331.6 GAX27979.1 - 1.7 8.8 7.5 2.8 8.0 7.5 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PRTP PF01366.18 GAX27979.1 - 3.7 5.5 8.2 5.5 4.9 8.2 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF2201_N PF13203.6 GAX27979.1 - 8.8 5.8 10.7 14 5.1 10.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain ADP_PFK_GK PF04587.15 GAX27979.1 - 9.9 4.6 8.5 21 3.5 8.5 1.5 1 1 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region TPR_12 PF13424.6 GAX27981.1 - 0.094 13.0 0.9 11 6.3 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 GAX27981.1 - 0.11 12.6 0.3 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 GAX27981.1 - 0.54 10.2 5.0 0.92 9.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 GAX27982.1 - 3.8e-28 98.7 0.1 4.9e-28 98.3 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP family Pkinase PF00069.25 GAX27984.1 - 4.3e-21 75.5 0.0 9e-21 74.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX27984.1 - 8.5e-15 54.7 0.0 1.5e-14 53.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX27984.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 GAX27985.1 - 8.6e-30 104.0 0.0 2.3e-29 102.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX27985.1 - 2e-28 99.4 0.0 2.3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX27985.1 - 0.07 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase HSF_DNA-bind PF00447.17 GAX27986.1 - 4.6e-19 68.8 0.0 7e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Globin PF00042.22 GAX27988.1 - 2.8e-08 34.3 0.0 4.8e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Globin CBM_6 PF03422.15 GAX27990.1 - 4.9e-08 33.3 0.5 0.0077 16.5 0.1 3.4 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) TPR_1 PF00515.28 GAX27991.1 - 4.7e-07 29.4 6.2 0.0019 17.9 1.7 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX27991.1 - 5.5e-07 29.2 6.3 0.0036 17.3 1.8 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX27991.1 - 9.6e-05 22.3 2.2 0.062 13.5 0.9 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX27991.1 - 0.00014 21.7 0.3 0.1 12.7 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX27991.1 - 0.00097 18.8 1.0 0.16 11.7 0.0 2.9 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 GAX27991.1 - 0.0011 19.5 2.6 2.6 8.8 2.4 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX27991.1 - 0.0047 17.2 4.6 0.16 12.3 1.8 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX27991.1 - 0.009 16.5 2.2 0.21 12.1 1.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX27991.1 - 0.018 15.6 4.8 0.16 12.6 1.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX27991.1 - 0.074 12.9 5.2 0.43 10.5 2.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX27991.1 - 0.093 13.6 0.7 24 6.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Oxidored_q6 PF01058.22 GAX27992.1 - 8.7e-24 83.8 0.1 1.3e-23 83.3 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit CBM_6 PF03422.15 GAX27993.1 - 2.3e-14 53.8 1.0 4.8e-12 46.3 0.1 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) CBM_35 PF16990.5 GAX27993.1 - 0.00089 19.5 1.0 1.7 8.9 0.0 2.9 2 1 0 2 2 2 2 Carbohydrate binding module (family 35) Hamartin PF04388.12 GAX27993.1 - 8.3 4.9 10.0 10 4.7 10.0 1.1 1 0 0 1 1 1 0 Hamartin protein CBM_6 PF03422.15 GAX27995.1 - 5.7e-36 123.6 5.4 2.3e-21 76.4 0.1 3.4 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) CBM_35 PF16990.5 GAX27995.1 - 8.1e-12 45.5 4.1 0.0013 19.0 0.0 3.2 3 0 0 3 3 3 3 Carbohydrate binding module (family 35) DUF5010_C PF18099.1 GAX27995.1 - 2.3e-08 34.1 0.2 5.8e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 DUF5010 C-terminal domain DUF4573 PF15140.6 GAX27995.1 - 0.0035 17.1 13.1 0.0069 16.2 13.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) DUF4813 PF16072.5 GAX27995.1 - 6.1 6.4 44.0 15 5.2 44.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) CBM_6 PF03422.15 GAX27996.1 - 2.7e-43 147.2 3.4 3.7e-22 78.9 0.2 3.5 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX27996.1 - 1.1e-13 51.3 1.2 1.5e-07 31.5 0.1 3.1 3 0 0 3 3 3 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX27996.1 - 0.00032 20.9 1.5 0.13 12.5 0.1 3.5 3 0 0 3 3 3 1 Carbohydrate binding module (family 35) GLTT PF01744.20 GAX27996.1 - 1.4 8.8 6.7 15 5.5 1.1 4.3 3 1 0 3 3 3 0 GLTT repeat (6 copies) PP2C PF00481.21 GAX27997.1 - 1.9e-27 96.5 0.0 2.9e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX27997.1 - 2.1e-09 37.3 0.0 3.4e-08 33.4 0.0 2.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX27997.1 - 2.3e-08 34.2 0.0 9.2e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) MCM PF00493.23 GAX27998.1 - 2.3e-80 268.9 0.0 4.3e-80 268.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 GAX27998.1 - 2.5e-23 82.3 1.0 7e-23 80.9 0.2 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 GAX27998.1 - 2e-22 79.4 1.2 4.6e-22 78.2 1.2 1.6 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 GAX27998.1 - 1.9e-11 43.7 1.6 1.9e-09 37.2 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX27998.1 - 4.4e-10 39.7 0.1 1.1e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAX27998.1 - 1.5e-07 31.2 0.2 4.9e-06 26.4 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAX27998.1 - 3.4e-06 26.9 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX27998.1 - 0.00072 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 GAX27998.1 - 0.0079 16.6 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX27998.1 - 0.015 15.7 0.1 0.045 14.1 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 GAX27998.1 - 0.093 13.1 0.3 6.1 7.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAX27998.1 - 0.13 11.2 0.0 0.32 9.9 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 GAX27998.1 - 0.13 12.5 0.1 1.2 9.4 0.1 2.6 1 1 0 1 1 1 0 AAA domain Amidase_2 PF01510.25 GAX27998.1 - 0.15 12.5 0.1 6.1 7.3 0.0 2.4 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase E1-E2_ATPase PF00122.20 GAX27999.1 - 5.8e-41 140.0 0.6 5.8e-41 140.0 0.6 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX27999.1 - 4.2e-39 134.1 0.2 4.2e-39 134.1 0.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 GAX27999.1 - 2.2e-13 49.7 0.0 5.6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAX27999.1 - 3.4e-13 49.5 0.0 6.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAX27999.1 - 1.3e-12 48.4 2.6 9.5e-10 39.1 0.4 3.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAX27999.1 - 0.013 15.2 1.3 0.21 11.3 1.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4265 PF14085.6 GAX27999.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Tic22 PF04278.12 GAX28000.1 - 4.4e-07 29.5 0.2 4.9e-06 26.1 0.2 2.1 1 1 0 1 1 1 1 Tic22-like family MFS_1 PF07690.16 GAX28001.1 - 2.5e-17 62.9 17.2 4.1e-17 62.1 17.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX28001.1 - 1.5e-09 37.2 4.0 1.9e-09 36.9 3.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltransf_25 PF13649.6 GAX28002.1 - 0.0038 17.9 0.0 0.007 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX28002.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28002.1 - 0.043 13.6 0.0 0.09 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAX28002.1 - 0.16 12.7 0.0 0.27 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.21 GAX28003.1 - 7.9e-15 54.8 0.0 2.9e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1974 PF09317.11 GAX28004.1 - 7.9e-45 153.6 0.0 3.1e-44 151.6 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 GAX28004.1 - 5.5e-14 52.8 0.0 1.2e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAX28004.1 - 1.6e-08 34.9 1.3 1.6e-08 34.9 1.3 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAX28004.1 - 8.4e-06 25.9 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain PseudoU_synth_2 PF00849.22 GAX28005.1 - 6.9e-15 55.5 0.0 1.3e-14 54.6 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase V-ATPase_G_2 PF16999.5 GAX28006.1 - 0.024 15.0 18.5 0.31 11.5 5.0 3.1 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit YliH PF10799.8 GAX28006.1 - 0.21 11.5 2.7 0.24 11.3 0.7 2.1 1 1 1 2 2 2 0 Biofilm formation protein (YliH/bssR) DUF2459 PF09601.10 GAX28006.1 - 0.22 11.3 1.2 0.23 11.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) DUF1640 PF07798.11 GAX28006.1 - 0.46 10.5 15.0 0.37 10.8 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) ApoO PF09769.9 GAX28006.1 - 0.48 10.4 2.9 0.68 9.9 0.8 2.2 2 1 0 2 2 2 0 Apolipoprotein O DUF4407 PF14362.6 GAX28006.1 - 1.8 7.9 13.0 3.3 7.0 13.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PEP-utilisers_N PF05524.13 GAX28006.1 - 8.6 6.6 12.5 2.3e+02 2.0 0.1 3.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Peptidase_M10 PF00413.24 GAX28007.1 - 0.00082 19.3 0.0 0.0012 18.7 0.0 1.3 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 GAX28007.1 - 0.00089 19.8 0.0 0.0019 18.7 0.0 1.7 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX28007.1 - 0.0073 16.5 0.4 0.014 15.5 0.4 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX28007.1 - 0.047 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SecA_PP_bind PF01043.20 GAX28007.1 - 0.07 13.8 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 SecA preprotein cross-linking domain Reprolysin_2 PF13574.6 GAX28007.1 - 0.14 12.1 0.2 0.23 11.3 0.2 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4518 PF15008.6 GAX28007.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Aminotran_3 PF00202.21 GAX28008.1 - 6.9e-107 357.6 0.0 9.2e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAX28008.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase PPR_2 PF13041.6 GAX28009.1 - 2.9e-12 46.6 0.0 2.6e-09 37.1 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 GAX28009.1 - 1.4e-08 34.4 0.1 4.6e-05 23.4 0.0 4.0 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.7 GAX28009.1 - 3.1e-06 26.8 0.0 0.0046 16.6 0.0 3.1 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 GAX28009.1 - 0.00051 20.1 0.6 0.13 12.4 0.0 3.2 2 1 2 4 4 4 2 Pentatricopeptide repeat domain TPR_14 PF13428.6 GAX28009.1 - 0.011 16.4 3.0 10 7.2 0.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 GAX28009.1 - 0.1 13.0 0.7 0.29 11.6 0.2 1.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain NCD2 PF04905.13 GAX28009.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) GTP_EFTU PF00009.27 GAX28010.1 - 1.3e-30 106.5 6.5 4.3e-29 101.4 6.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAX28010.1 - 6.6e-23 80.8 2.5 1.1e-22 80.1 0.7 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 GAX28010.1 - 4.4e-12 46.1 0.3 1.3e-11 44.6 0.3 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 GAX28010.1 - 5.1e-08 32.6 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 GAX28010.1 - 4.9e-07 29.4 1.4 1.1e-06 28.3 0.8 1.9 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX28010.1 - 1.4e-06 28.4 2.5 0.00014 21.8 0.1 2.6 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 GAX28010.1 - 5.4e-06 26.0 0.3 2.1e-05 24.0 0.3 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAX28010.1 - 9.3e-06 25.3 0.2 1.6e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 GAX28010.1 - 2.3e-05 23.9 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 GAX28010.1 - 5.3e-05 23.5 7.2 0.0037 17.6 0.1 3.9 4 0 0 4 4 4 2 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 GAX28010.1 - 0.00038 20.3 0.1 0.00075 19.4 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 GAX28010.1 - 0.0047 17.0 0.1 0.49 10.4 0.0 2.6 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 GAX28010.1 - 0.0082 16.1 0.3 0.022 14.7 0.3 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Roc PF08477.13 GAX28010.1 - 0.0092 16.2 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF742 PF05331.11 GAX28010.1 - 0.015 15.1 0.1 0.049 13.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF742) NTP_transf_3 PF12804.7 GAX28010.1 - 0.043 14.2 0.4 0.27 11.6 0.0 2.3 2 0 0 2 2 2 0 MobA-like NTP transferase domain AIG1 PF04548.16 GAX28010.1 - 0.047 13.0 0.1 0.13 11.6 0.1 1.6 1 1 1 2 2 2 0 AIG1 family PduV-EutP PF10662.9 GAX28010.1 - 0.13 12.0 0.1 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 GAX28010.1 - 0.18 12.3 0.1 0.46 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain Siah-Interact_N PF09032.11 GAX28011.1 - 0.06 13.7 1.7 0.74 10.2 0.4 3.4 3 0 0 3 3 3 0 Siah interacting protein, N terminal Branch PF02485.21 GAX28012.1 - 1.7e-18 67.1 0.4 5.3e-18 65.4 0.4 1.7 1 1 0 1 1 1 1 Core-2/I-Branching enzyme MucBP PF06458.12 GAX28012.1 - 0.064 14.3 0.0 0.4 11.7 0.0 2.2 2 0 0 2 2 2 0 MucBP domain HD PF01966.22 GAX28013.1 - 5.3e-14 52.5 0.5 1.3e-13 51.2 0.5 1.7 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 GAX28013.1 - 0.00085 19.1 0.2 0.0019 18.0 0.2 1.7 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HDOD PF08668.12 GAX28013.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 HDOD domain PDEase_I PF00233.19 GAX28013.1 - 0.0057 16.4 0.4 0.0099 15.6 0.4 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-MYND PF01753.18 GAX28014.1 - 2.9e-06 27.3 3.5 9.3e-06 25.6 3.5 1.9 1 0 0 1 1 1 1 MYND finger DUF1016_N PF17761.1 GAX28014.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 DUF1016 N-terminal domain zf-Mss51 PF13824.6 GAX28014.1 - 4.3 7.5 11.2 0.33 11.1 4.0 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Flavokinase PF01687.17 GAX28015.1 - 4.2e-31 107.5 0.0 6.5e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Methyltransf_23 PF13489.6 GAX28015.1 - 4.4e-13 49.4 0.0 1.1e-12 48.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX28015.1 - 6.1e-13 49.3 0.0 1.4e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28015.1 - 2.2e-10 40.5 0.0 6.6e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX28015.1 - 2.1e-09 38.0 0.0 4.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX28015.1 - 3.2e-09 37.3 0.0 2e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX28015.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAX28015.1 - 0.00035 20.2 0.0 0.00065 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAX28015.1 - 0.00037 20.5 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 GAX28015.1 - 0.0009 18.7 0.0 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 RNA methyltransferase DUF938 PF06080.12 GAX28015.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Pyr_redox_2 PF07992.14 GAX28016.1 - 2.9e-43 148.2 0.3 4.2e-43 147.7 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX28016.1 - 4.8e-17 62.2 0.0 1.2e-15 57.7 0.0 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX28016.1 - 1.9e-13 50.8 1.1 4.5e-10 40.0 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX28016.1 - 0.0002 20.7 0.0 0.0082 15.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX28016.1 - 0.00042 19.7 0.3 0.43 9.8 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX28016.1 - 0.0011 18.7 0.3 0.0029 17.2 0.3 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 GAX28016.1 - 0.013 15.4 1.1 3 7.7 0.1 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 GAX28016.1 - 0.02 14.0 0.0 0.063 12.4 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAX28016.1 - 0.13 12.5 0.6 3.3 8.0 0.2 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_trans_4_5 PF16994.5 GAX28016.1 - 0.16 11.6 0.0 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl-transferase family 4 ApbA PF02558.16 GAX28016.1 - 0.46 10.1 1.7 6.3 6.4 0.0 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Ribosomal_L4 PF00573.22 GAX28017.1 - 4e-53 180.0 0.1 5.2e-53 179.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PPR_2 PF13041.6 GAX28019.1 - 7e-26 90.2 6.0 4.9e-08 33.0 0.1 7.1 6 2 1 7 7 7 6 PPR repeat family PPR_3 PF13812.6 GAX28019.1 - 7.3e-18 64.4 0.2 1.9e-06 27.8 0.1 5.9 3 1 4 7 7 7 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX28019.1 - 2.1e-16 59.3 14.2 0.017 14.8 0.2 9.3 8 2 0 8 8 8 4 PPR repeat PPR PF01535.20 GAX28019.1 - 2.7e-14 52.3 20.4 1.3e-05 25.1 0.1 9.9 9 2 0 9 9 9 4 PPR repeat PPR_long PF17177.4 GAX28019.1 - 7.5e-10 38.5 1.7 3.6e-05 23.2 0.6 3.6 1 1 3 4 4 4 2 Pentacotripeptide-repeat region of PRORP Hpt PF01627.23 GAX28019.1 - 0.084 13.2 1.4 4.9 7.5 0.2 2.7 2 0 0 2 2 2 0 Hpt domain TPR_19 PF14559.6 GAX28019.1 - 0.095 13.2 2.1 0.28 11.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GAX28019.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.9 3 0 0 3 3 3 0 Coatomer epsilon subunit ABC_membrane PF00664.23 GAX28020.1 - 3e-79 266.5 17.7 7.9e-42 143.8 2.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX28020.1 - 1e-34 120.0 0.1 2e-34 119.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 GAX28020.1 - 0.004 16.6 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAX28020.1 - 0.027 14.4 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 GAX28020.1 - 0.035 14.3 0.9 0.63 10.3 0.9 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 GAX28020.1 - 0.074 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 GAX28020.1 - 0.077 12.8 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain LPP20 PF02169.16 GAX28020.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 LPP20 lipoprotein CytB6-F_Fe-S PF08802.10 GAX28020.1 - 0.37 10.8 6.2 0.083 12.9 1.9 2.3 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Methyltransf_FA PF12248.8 GAX28021.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase ABC_membrane PF00664.23 GAX28022.1 - 4.3e-14 52.8 0.6 5.1e-14 52.6 0.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 GAX28023.1 - 1.3e-38 133.3 7.7 1.9e-38 132.7 7.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAX28023.1 - 1.9e-20 73.8 0.1 4.7e-20 72.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 GAX28023.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 GAX28023.1 - 0.042 13.1 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 GAX28023.1 - 0.044 13.5 0.5 0.1 12.3 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain LPP20 PF02169.16 GAX28023.1 - 0.073 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 LPP20 lipoprotein AAA_15 PF13175.6 GAX28023.1 - 0.22 11.2 0.0 0.78 9.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain CytB6-F_Fe-S PF08802.10 GAX28023.1 - 4 7.5 6.6 0.85 9.7 1.4 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit DnaJ PF00226.31 GAX28024.1 - 7.2e-16 58.1 3.1 1.6e-15 56.9 3.1 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 GAX28024.1 - 1.8e-11 43.9 1.0 9.1e-09 35.1 0.0 3.8 3 1 0 3 3 3 1 X-domain of DnaJ-containing TMA7 PF09072.10 GAX28024.1 - 2.7 8.9 6.1 38 5.2 2.0 2.4 2 0 0 2 2 2 0 Translation machinery associated TMA7 DUF4442 PF14539.6 GAX28026.1 - 1.1e-18 67.6 0.1 1.3e-18 67.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Glyco_hydro2_C5 PF18565.1 GAX28026.1 - 0.052 13.4 0.1 0.15 11.9 0.0 1.8 1 1 1 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 Ribosomal_S30AE PF02482.19 GAX28026.1 - 0.057 14.2 0.6 0.12 13.2 0.6 1.5 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein YiiD_C PF09500.10 GAX28026.1 - 0.066 13.0 0.1 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) RNase_Zc3h12a PF11977.8 GAX28027.1 - 1.3e-09 38.0 0.0 5.8e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain AIM24 PF01987.17 GAX28028.1 - 4.6e-62 209.4 1.9 5.5e-62 209.1 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 LigT_PEase PF02834.16 GAX28030.1 - 2.9e-07 30.6 0.1 0.0067 16.6 0.0 3.1 3 0 0 3 3 3 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 GAX28030.1 - 1e-06 28.7 0.5 2.3e-06 27.6 0.5 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Rubredoxin PF00301.20 GAX28031.1 - 1.3e-17 63.5 1.4 2e-17 63.0 1.4 1.3 1 0 0 1 1 1 1 Rubredoxin zf-C2H2_3 PF13878.6 GAX28031.1 - 0.085 12.7 0.7 0.52 10.2 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO PHD_4 PF16866.5 GAX28031.1 - 0.1 12.7 1.9 0.21 11.7 1.9 1.7 1 1 0 1 1 1 0 PHD-finger Rubredoxin_2 PF18073.1 GAX28031.1 - 0.2 11.4 1.9 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Lactate_perm PF02652.14 GAX28032.1 - 1e-65 222.5 33.1 3.9e-34 118.3 5.5 2.0 2 0 0 2 2 2 2 L-lactate permease Cyclotide PF03784.13 GAX28032.1 - 0.59 10.3 4.3 1.2 9.2 4.3 1.5 1 0 0 1 1 1 0 Cyclotide family Cyclin_N PF00134.23 GAX28033.1 - 0.00047 19.9 0.1 0.0011 18.7 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 GAX28033.1 - 0.00095 19.5 0.0 0.0064 16.9 0.0 2.1 2 0 0 2 2 2 1 Cyclin C-terminal domain Zn_clus PF00172.18 GAX28034.1 - 4.3e-09 36.4 10.3 7.1e-09 35.7 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3754 PF12576.8 GAX28035.1 - 1.9e-25 89.4 0.0 4e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) Aldo_ket_red PF00248.21 GAX28037.1 - 1.7e-51 175.2 0.0 1.9e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1283 PF06932.11 GAX28037.1 - 0.091 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) DNA_pol3_theta PF06440.11 GAX28037.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit DUF1065 PF06358.11 GAX28038.1 - 0.096 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) DUF4474 PF14751.6 GAX28038.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) DUF805 PF05656.14 GAX28039.1 - 0.0084 16.5 0.3 0.01 16.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DUF1035 PF06281.12 GAX28039.1 - 0.069 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF2070 PF09843.9 GAX28040.1 - 0.048 11.9 3.3 0.058 11.7 3.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TraQ PF09679.10 GAX28040.1 - 0.83 9.6 5.8 0.54 10.2 0.4 2.6 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF647 PF04884.14 GAX28042.1 - 3e-58 197.3 0.8 4.2e-58 196.8 0.8 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis BLM10_mid PF16507.5 GAX28043.1 - 3.5e-47 161.3 0.0 1.7e-46 159.0 0.0 2.2 2 1 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 GAX28043.1 - 2.4e-21 75.4 0.1 1.1e-20 73.3 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 GAX28043.1 - 0.66 10.4 5.8 10 6.7 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat ELYS PF13934.6 GAX28044.1 - 0.00038 20.5 0.1 0.00092 19.3 0.2 1.6 1 1 0 1 1 1 1 Nuclear pore complex assembly Peptidase_M9 PF01752.17 GAX28044.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Collagenase YXWGXW PF12779.7 GAX28044.1 - 0.14 12.3 5.8 0.25 11.6 5.8 1.4 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) TPR_1 PF00515.28 GAX28045.1 - 1.7e-22 78.2 24.9 6.3e-06 25.8 2.0 7.1 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28045.1 - 2.8e-18 64.5 36.7 1.4e-05 24.9 2.7 7.0 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAX28045.1 - 2.1e-08 34.7 36.5 0.0057 17.3 11.3 5.5 6 0 0 6 6 4 3 Tetratricopeptide repeat FYVE PF01363.21 GAX28045.1 - 4.7e-08 33.1 1.1 1.1e-07 31.9 1.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Synaptobrevin PF00957.21 GAX28045.1 - 5.6e-06 26.1 3.3 1.2e-05 25.0 0.4 2.4 2 0 0 2 2 2 1 Synaptobrevin TPR_11 PF13414.6 GAX28045.1 - 1.6e-05 24.5 19.4 0.1 12.3 0.1 5.0 4 1 1 5 5 5 3 TPR repeat TPR_8 PF13181.6 GAX28045.1 - 1.8e-05 24.6 23.6 0.055 13.7 0.5 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat Ank_2 PF12796.7 GAX28045.1 - 0.0001 22.8 0.0 0.1 13.2 0.0 3.6 1 1 3 4 4 4 2 Ankyrin repeats (3 copies) TPR_14 PF13428.6 GAX28045.1 - 0.00028 21.5 34.7 0.0046 17.7 0.9 7.9 3 3 5 8 8 8 2 Tetratricopeptide repeat FYVE_2 PF02318.16 GAX28045.1 - 0.0012 19.0 0.7 0.0012 19.0 0.7 1.9 2 0 0 2 2 1 1 FYVE-type zinc finger Ank PF00023.30 GAX28045.1 - 0.0013 19.1 0.1 0.91 10.1 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat TPR_12 PF13424.6 GAX28045.1 - 0.0018 18.5 24.8 0.39 11.0 10.7 5.3 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAX28045.1 - 0.0025 18.3 6.0 0.0025 18.3 6.0 5.1 3 2 3 6 6 6 1 Tetratricopeptide repeat Ank_3 PF13606.6 GAX28045.1 - 0.012 16.1 0.1 1.4 9.8 0.0 4.0 4 0 0 4 4 3 0 Ankyrin repeat TPR_17 PF13431.6 GAX28045.1 - 0.042 14.2 0.1 0.042 14.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAX28045.1 - 0.11 12.6 16.2 0.22 11.7 3.8 4.2 2 2 2 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 GAX28045.1 - 0.11 12.9 17.8 0.73 10.3 11.7 3.9 2 2 0 3 3 3 0 Bacterial transcriptional activator domain DUF4428 PF14471.6 GAX28045.1 - 0.16 11.9 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) ANAPC3 PF12895.7 GAX28045.1 - 0.54 10.5 18.3 0.6 10.4 6.2 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAX28045.1 - 2.8 7.9 25.5 2.1 8.3 2.8 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat LBR_tudor PF09465.10 GAX28046.1 - 1.3e-06 28.1 11.6 0.0068 16.2 0.6 3.4 3 0 0 3 3 3 3 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 GAX28046.1 - 2.6 8.0 6.1 13 5.7 0.1 3.5 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain AFT PF08731.11 GAX28049.1 - 0.045 14.2 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT IF-2B PF01008.17 GAX28050.1 - 1.7e-69 234.2 0.2 2.5e-69 233.6 0.2 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family APH PF01636.23 GAX28050.1 - 9.4e-15 55.2 0.0 3.4e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX28050.1 - 0.0062 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase UPF0113_N PF17833.1 GAX28051.1 - 1.1e-31 109.3 0.3 1.6e-31 108.7 0.3 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 GAX28051.1 - 2e-21 76.0 0.0 3.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 GAX28051.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain PUA PF01472.20 GAX28051.1 - 0.074 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 PUA domain WD40 PF00400.32 GAX28052.1 - 7.5e-12 45.6 10.3 1.4e-05 25.7 0.0 6.3 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28052.1 - 3.8e-07 30.3 0.1 0.0074 16.6 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX28052.1 - 0.0039 15.9 0.2 0.0039 15.9 0.2 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ApbA_C PF08546.11 GAX28054.1 - 5.7e-31 107.3 0.0 1.3e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAX28054.1 - 9.3e-23 80.6 0.0 1.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TfuA PF07812.12 GAX28054.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 TfuA-like protein SecY PF00344.20 GAX28055.1 - 2.3e-71 240.6 13.2 2.7e-71 240.4 13.2 1.0 1 0 0 1 1 1 1 SecY translocase Tlr3_TMD PF17968.1 GAX28055.1 - 0.07 13.3 1.2 0.07 13.3 1.2 3.0 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain Ank_2 PF12796.7 GAX28056.1 - 4.9e-14 52.7 0.1 3.8e-07 30.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX28056.1 - 3.1e-10 40.4 0.2 0.0014 19.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX28056.1 - 4.5e-09 35.8 0.2 0.00041 20.6 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 GAX28056.1 - 2.5e-07 30.8 0.2 0.0014 19.0 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX28056.1 - 7.2e-05 23.0 0.2 0.042 14.2 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) F-box PF00646.33 GAX28056.1 - 0.00029 20.7 0.0 0.0009 19.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain zf-CCCH_3 PF15663.5 GAX28057.1 - 0.00011 22.4 4.7 0.00039 20.6 4.7 1.9 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 GAX28057.1 - 0.0022 17.8 11.3 1.5 8.8 0.6 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1378 PF07125.11 GAX28057.1 - 0.01 15.9 1.8 20 5.5 0.0 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1378) zf-CCCH_2 PF14608.6 GAX28057.1 - 0.27 11.8 10.0 0.78 10.3 2.5 2.9 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 GAX28057.1 - 0.45 10.6 11.8 5.3 7.2 4.2 3.6 3 1 0 3 3 3 0 Zinc finger domain Torus PF16131.5 GAX28057.1 - 2.3 8.9 11.4 1.7 9.4 0.1 3.7 1 1 2 4 4 4 0 Torus domain zf-C3H1 PF10650.9 GAX28057.1 - 5.4 6.8 10.6 6.3 6.6 0.5 2.8 3 0 0 3 3 3 0 Putative zinc-finger domain DAO PF01266.24 GAX28058.1 - 3.5e-52 178.2 0.9 4.8e-52 177.7 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX28058.1 - 0.014 14.5 2.3 0.017 14.2 1.3 1.7 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 GAX28058.1 - 0.052 12.8 0.1 3.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 GAX28058.1 - 0.055 12.7 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX28058.1 - 0.063 12.5 0.4 0.43 9.8 0.1 2.2 2 1 1 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAX28058.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 GAX28058.1 - 0.092 13.0 0.1 0.29 11.4 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAX28058.1 - 0.24 10.7 2.2 2.8 7.2 2.2 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase SLATT_1 PF18181.1 GAX28059.1 - 0.055 13.4 2.9 0.18 11.7 0.0 2.8 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Formyl_trans_N PF00551.19 GAX28060.1 - 1.1e-35 123.1 0.0 1.4e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 GAX28060.1 - 1.4e-12 47.7 0.0 2.2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Ank_4 PF13637.6 GAX28061.1 - 1.3e-13 51.2 1.6 0.0014 19.1 0.1 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX28061.1 - 4.9e-13 49.5 2.5 0.0017 18.9 0.0 4.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX28061.1 - 1.9e-12 46.2 1.3 0.048 14.2 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAX28061.1 - 2.6e-08 34.0 2.0 0.00016 21.9 0.0 4.9 3 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 GAX28061.1 - 8.8e-05 22.8 3.1 3.7 8.1 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 GAX28063.1 - 2e-09 37.8 1.7 0.00059 20.3 0.2 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX28063.1 - 1.5e-08 35.1 0.1 0.023 15.3 0.1 3.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX28063.1 - 2.2e-06 27.6 2.6 0.0067 16.9 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 GAX28063.1 - 0.00026 21.3 5.5 0.59 10.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX28063.1 - 0.024 14.9 0.0 4.5 7.7 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 GAX28064.1 - 1.3e-11 44.7 7.7 1.3e-11 44.7 7.7 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX28064.1 - 5.9e-08 32.4 6.4 1.4e-07 31.2 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX28064.1 - 7.1e-08 32.1 1.4 1.7e-07 30.9 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAX28064.1 - 3.9e-05 23.6 6.3 0.00011 22.1 6.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAX28064.1 - 5.5e-05 23.4 12.4 5.5e-05 23.4 12.4 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX28064.1 - 0.00018 21.3 7.1 0.00018 21.3 7.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX28064.1 - 0.0003 20.6 6.4 0.0003 20.6 6.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX28064.1 - 0.00033 20.6 8.0 0.00033 20.6 8.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAX28064.1 - 0.0024 17.4 6.2 0.0059 16.2 6.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX28064.1 - 0.012 15.5 7.7 0.012 15.5 7.7 2.3 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 GAX28064.1 - 0.02 14.3 0.3 0.029 13.8 0.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 GAX28064.1 - 0.24 11.6 7.1 1 9.6 7.1 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 GAX28064.1 - 0.39 11.1 11.1 0.46 10.8 8.9 2.2 2 0 0 2 2 2 0 RING-like domain ATP1G1_PLM_MAT8 PF02038.16 GAX28064.1 - 0.59 9.6 3.7 28 4.2 1.9 2.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family FANCL_C PF11793.8 GAX28064.1 - 0.74 10.0 16.9 0.18 12.0 10.4 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 GAX28064.1 - 1.4 9.1 6.7 6.2 6.9 6.7 2.1 1 1 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 GAX28065.1 - 2.1e-12 47.2 5.6 2.1e-12 47.2 5.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAX28065.1 - 2.4e-08 33.7 5.6 6.6e-08 32.3 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX28065.1 - 4.6e-08 32.7 0.6 1.4e-07 31.1 0.6 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAX28065.1 - 1.4e-07 31.6 11.0 1.4e-06 28.5 11.0 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAX28065.1 - 3.7e-06 26.7 4.2 1e-05 25.3 4.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX28065.1 - 8.2e-05 22.5 0.2 8.2e-05 22.5 0.2 2.2 2 1 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 GAX28065.1 - 0.0024 18.0 7.4 0.011 15.9 7.4 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX28065.1 - 0.0062 16.1 7.8 0.0062 16.1 7.8 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 GAX28065.1 - 0.0077 16.4 3.4 0.0077 16.4 3.4 1.9 2 0 0 2 2 2 1 Zinc-ribbon like family zf-C3HC4_3 PF13920.6 GAX28065.1 - 0.014 15.2 8.0 0.047 13.6 8.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX28065.1 - 0.016 15.2 8.2 0.016 15.2 8.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX28065.1 - 0.035 14.2 3.5 0.11 12.5 3.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 GAX28065.1 - 0.04 14.2 6.9 0.18 12.2 6.9 2.2 1 0 0 1 1 1 0 RING-like domain ABC1 PF03109.16 GAX28066.1 - 2.5e-24 85.7 0.0 5e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX28066.1 - 1.2e-05 25.4 0.0 4e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX28066.1 - 0.0016 17.9 0.6 0.27 10.6 0.3 3.0 2 1 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 GAX28066.1 - 0.11 12.1 1.1 0.37 10.4 0.9 1.9 1 1 1 2 2 2 0 RIO1 family Histone_H2A_C PF16211.5 GAX28069.1 - 1.4e-17 63.1 0.8 3.6e-17 61.8 0.8 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAX28069.1 - 4.9e-15 56.1 0.0 4.9e-15 56.1 0.0 5.7 4 3 1 5 5 5 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAX28069.1 - 0.00016 21.9 0.8 0.0014 18.9 0.0 3.1 4 0 0 4 4 4 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC1 PF03109.16 GAX28070.1 - 6.2e-27 94.1 0.0 1.3e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX28070.1 - 0.00093 19.2 0.9 0.0026 17.7 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX28070.1 - 0.0014 18.0 0.0 0.16 11.3 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain ATP-synt_C PF00137.21 GAX28071.1 - 9.7e-32 109.1 23.7 6.8e-18 64.8 4.1 2.4 2 1 0 2 2 2 2 ATP synthase subunit C DUF2207 PF09972.9 GAX28071.1 - 0.00015 20.6 0.2 0.00026 19.9 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) CBS PF00571.28 GAX28072.1 - 4.2e-18 65.5 1.2 4.4e-08 33.5 0.2 2.7 2 0 0 2 2 2 2 CBS domain DHH PF01368.20 GAX28072.1 - 2.6e-12 46.8 0.3 1.4e-11 44.6 0.0 2.3 2 1 0 2 2 2 1 DHH family EF-hand_7 PF13499.6 GAX28072.1 - 2.9e-11 43.7 0.3 2.1e-10 40.9 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX28072.1 - 4.6e-09 35.2 0.2 0.00064 19.1 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX28072.1 - 1.3e-07 31.0 0.2 0.034 14.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAX28072.1 - 1.4e-07 31.3 0.0 3.1e-06 26.9 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAX28072.1 - 4.5e-06 25.9 0.3 0.054 13.0 0.0 2.5 2 0 0 2 2 2 2 EF hand DHHA1 PF02272.19 GAX28072.1 - 0.00045 20.6 1.4 0.00074 20.0 0.0 2.1 2 0 0 2 2 2 1 DHHA1 domain SUIM_assoc PF16619.5 GAX28072.1 - 2.3 8.4 6.8 11 6.1 0.6 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 LEA_4 PF02987.16 GAX28074.1 - 0.0001 22.3 2.7 0.0001 22.3 2.7 8.9 6 2 3 9 9 9 3 Late embryogenesis abundant protein YtxH PF12732.7 GAX28074.1 - 0.00098 19.6 38.2 0.15 12.6 1.9 5.9 2 2 1 3 3 3 1 YtxH-like protein DUF883 PF05957.13 GAX28074.1 - 0.0013 19.3 24.2 0.18 12.4 0.3 4.8 2 2 1 4 4 4 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 GAX28074.1 - 0.0049 16.8 19.5 0.0049 16.8 11.4 2.8 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain ApoO PF09769.9 GAX28074.1 - 0.11 12.4 10.8 1.8 8.5 3.2 3.9 3 1 1 4 4 4 0 Apolipoprotein O Prominin PF05478.11 GAX28074.1 - 2.4 6.0 4.7 3.1 5.6 4.7 1.3 1 1 0 1 1 1 0 Prominin Grg1 PF11034.8 GAX28074.1 - 3.1 8.1 36.9 0.11 12.7 1.3 7.2 1 1 5 6 6 6 0 Glucose-repressible protein Grg1 PCYCGC PF13798.6 GAX28075.1 - 0.073 12.9 0.5 0.1 12.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function with PCYCGC motif DUF655 PF04919.12 GAX28076.1 - 0.043 13.8 0.8 0.073 13.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF655) RisS_PPD PF16524.5 GAX28076.1 - 0.069 13.4 4.1 0.35 11.1 0.9 2.3 1 1 1 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS ThiD2 PF17792.1 GAX28076.1 - 0.19 12.2 3.8 0.37 11.3 3.8 1.5 1 0 0 1 1 1 0 ThiD2 family DUF3612 PF12268.8 GAX28076.1 - 0.49 10.5 3.0 0.71 10.0 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) TMF_TATA_bd PF12325.8 GAX28076.1 - 5.4 7.3 18.6 4.9 7.4 2.4 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 GAX28076.1 - 5.5 7.7 10.0 2.9 8.6 0.4 2.8 1 1 1 2 2 2 0 Initiation control protein YabA DUF5471 PF17565.2 GAX28076.1 - 6 7.2 11.6 6.1 7.2 1.3 3.6 1 1 2 3 3 3 0 Family of unknown function (DUF5471) Ubie_methyltran PF01209.18 GAX28077.1 - 3.9e-36 124.6 0.0 4.6e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAX28077.1 - 2.6e-14 53.7 0.1 5.1e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX28077.1 - 8.3e-14 52.0 0.0 1.6e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28077.1 - 1.5e-11 44.3 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX28077.1 - 6e-11 42.4 0.0 8.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX28077.1 - 5.3e-08 33.5 0.0 8.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX28077.1 - 0.033 13.8 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M3 PF01432.20 GAX28079.1 - 1.4e-24 87.2 0.0 1.3e-23 84.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 GAX28079.1 - 3.2e-06 26.1 0.3 4.5e-06 25.6 0.3 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme RPN7 PF10602.9 GAX28079.1 - 0.1 12.3 1.6 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Ank_2 PF12796.7 GAX28080.1 - 7.2e-20 71.4 8.9 1.9e-10 41.2 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX28080.1 - 2.9e-16 57.9 3.3 0.00022 21.4 0.0 5.8 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 GAX28080.1 - 1.8e-15 57.1 0.6 0.00027 21.4 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAX28080.1 - 9.1e-12 44.9 6.3 0.096 13.2 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAX28080.1 - 5.3e-08 33.0 0.7 0.08 13.3 0.1 4.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) DUF1871 PF08958.10 GAX28081.1 - 0.18 12.1 0.0 0.59 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) NnrU PF07298.11 GAX28082.1 - 5.6e-17 61.9 0.2 8.4e-14 51.6 0.1 2.9 2 1 0 2 2 2 2 NnrU protein RCC1 PF00415.18 GAX28085.1 - 6.2e-36 122.8 29.1 8.2e-11 42.4 0.1 8.4 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX28085.1 - 1.1e-25 88.8 31.2 1.7e-09 37.2 0.6 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 GAX28085.1 - 9.9e-06 26.1 0.1 2.5e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-met PF12874.7 GAX28085.1 - 1.3e-05 25.4 0.8 1.3e-05 25.4 0.8 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SRP9-21 PF05486.12 GAX28085.1 - 0.00015 22.0 1.4 0.0032 17.8 0.2 2.7 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) zf-C2H2_jaz PF12171.8 GAX28085.1 - 0.0002 21.5 0.7 0.00061 20.0 0.7 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ank_4 PF13637.6 GAX28085.1 - 0.00056 20.4 0.1 0.0014 19.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAX28085.1 - 0.0025 18.1 0.1 2.2 8.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX28085.1 - 0.011 16.2 0.1 11 7.0 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat zf-U1 PF06220.12 GAX28085.1 - 9.2 6.1 6.1 4.2 7.2 0.7 2.9 3 0 0 3 3 3 0 U1 zinc finger DSBA PF01323.20 GAX28086.1 - 0.00063 19.6 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 GAX28086.1 - 0.015 15.5 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 GAX28086.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain LRR_6 PF13516.6 GAX28087.1 - 7.7 6.8 7.0 2.3 8.5 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Proteasome PF00227.26 GAX28088.1 - 1.2e-08 34.6 0.0 0.00027 20.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Ank_3 PF13606.6 GAX28092.1 - 2.5e-19 67.3 0.7 0.00093 19.5 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 GAX28092.1 - 3e-19 69.4 0.0 2.6e-12 47.1 0.2 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX28092.1 - 3.3e-15 56.2 0.6 1.7e-07 31.7 0.1 4.4 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 GAX28092.1 - 3.8e-15 55.6 0.5 0.0014 19.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAX28092.1 - 7.1e-14 51.7 3.0 4.7e-05 23.6 0.4 3.9 3 1 0 4 4 4 3 Ankyrin repeats (many copies) GNAT_acetyltr_2 PF13718.6 GAX28093.1 - 3.6e-95 317.7 1.9 7.1e-94 313.4 0.0 2.8 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 GAX28093.1 - 8.7e-63 212.2 0.0 8.7e-63 212.2 0.0 1.9 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 GAX28093.1 - 1.3e-53 181.4 0.1 3.9e-53 179.9 0.1 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 GAX28093.1 - 1.1e-29 102.2 0.0 2.9e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 GAX28093.1 - 0.063 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX28093.1 - 0.15 12.5 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RseA_C PF03873.13 GAX28094.1 - 0.00085 19.5 0.3 0.0018 18.5 0.3 1.5 1 0 0 1 1 1 1 Anti sigma-E protein RseA, C-terminal domain YndJ PF14158.6 GAX28094.1 - 0.049 13.0 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 YndJ-like protein Leu_Phe_trans PF03588.14 GAX28095.1 - 0.087 12.3 0.1 0.24 10.9 0.1 1.6 1 1 1 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase 60KD_IMP PF02096.20 GAX28096.1 - 1.9e-43 148.2 0.1 2.7e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein ArsP_1 PF03773.13 GAX28096.1 - 0.038 13.1 0.0 5.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Predicted permease COX6C PF02937.15 GAX28096.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc RRM_1 PF00076.22 GAX28097.1 - 9.2e-19 67.0 0.4 1.9e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-Q PF13094.6 GAX28097.1 - 0.0037 17.5 1.3 0.0046 17.2 1.3 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 GAX28097.1 - 0.015 15.8 10.3 0.024 15.2 10.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 GAX28097.1 - 0.04 14.5 5.2 0.062 13.9 5.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA ADIP PF11559.8 GAX28097.1 - 0.053 13.6 9.7 0.092 12.8 9.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Nup35_RRM_2 PF14605.6 GAX28097.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CpG_bind_C PF12269.8 GAX28097.1 - 0.084 12.6 1.4 0.096 12.5 1.4 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Spc24 PF08286.11 GAX28097.1 - 0.21 11.8 5.8 0.34 11.2 5.8 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF812 PF05667.11 GAX28097.1 - 0.31 9.9 8.2 0.39 9.5 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RmuC PF02646.16 GAX28097.1 - 0.4 9.8 5.3 0.59 9.2 5.3 1.2 1 0 0 1 1 1 0 RmuC family FlxA PF14282.6 GAX28097.1 - 0.43 10.6 6.7 0.63 10.1 6.7 1.2 1 0 0 1 1 1 0 FlxA-like protein T2SSM PF04612.12 GAX28097.1 - 0.51 10.4 2.1 0.94 9.5 2.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M UPF0242 PF06785.11 GAX28097.1 - 1.2 9.2 9.3 1.8 8.6 9.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 GAX28097.1 - 3.2 8.2 7.0 5.9 7.4 7.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GRP PF07172.11 GAX28097.1 - 3.2 8.5 10.7 0.87 10.3 5.8 2.2 2 0 0 2 2 2 0 Glycine rich protein family GrpE PF01025.19 GAX28097.1 - 3.3 7.4 10.1 4.9 6.8 10.1 1.2 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 GAX28097.1 - 3.5 7.5 6.5 5.9 6.7 6.5 1.4 1 0 0 1 1 1 0 Septum formation initiator RRM_1 PF00076.22 GAX28098.1 - 1.5e-30 104.8 0.0 1.7e-13 50.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 GAX28098.1 - 0.00011 23.2 0.2 0.00045 21.3 0.1 2.2 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.6 GAX28098.1 - 0.00019 21.0 0.0 0.0048 16.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAP1 PF07218.11 GAX28098.1 - 0.54 8.5 12.7 0.77 8.0 12.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SPX PF03105.19 GAX28098.1 - 2.9 7.7 25.3 7.2 6.4 25.3 1.6 1 0 0 1 1 1 0 SPX domain LRRFIP PF09738.9 GAX28099.1 - 0.00073 19.1 16.6 0.00073 19.1 16.6 4.9 3 1 2 5 5 5 2 LRRFIP family Tropomyosin PF00261.20 GAX28099.1 - 0.0026 17.2 26.5 0.0026 17.2 26.5 7.0 1 1 6 7 7 7 3 Tropomyosin T7SS_ESX_EspC PF10824.8 GAX28099.1 - 0.0027 18.2 1.0 0.0027 18.2 1.0 4.2 3 2 1 4 4 4 1 Excreted virulence factor EspC, type VII ESX diderm Cohesin PF00963.18 GAX28099.1 - 0.033 14.4 0.6 8.8 6.6 0.0 2.8 2 1 0 2 2 2 0 Cohesin domain RT_RNaseH PF17917.1 GAX28099.1 - 0.45 10.8 0.1 0.45 10.8 0.1 4.1 4 0 0 4 4 4 0 RNase H-like domain found in reverse transcriptase UXS1_N PF11803.8 GAX28099.1 - 2.9 8.3 6.7 8.3 6.9 0.0 4.3 5 0 0 5 5 5 0 UDP-glucuronate decarboxylase N-terminal Pox_A_type_inc PF04508.12 GAX28099.1 - 5.3 7.1 36.7 0.92 9.5 0.6 7.9 9 0 0 9 9 9 0 Viral A-type inclusion protein repeat ATG16 PF08614.11 GAX28100.1 - 0.014 15.6 58.2 0.1 12.8 33.5 3.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) PDEase_I PF00233.19 GAX28100.1 - 0.017 14.9 0.3 0.017 14.9 0.3 2.4 2 1 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase 7tm_3 PF00003.22 GAX28101.1 - 7.5e-37 127.3 13.2 1e-36 126.9 12.4 1.6 1 1 1 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 GAX28101.1 - 3.7e-20 72.6 0.0 4.2e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 GAX28101.1 - 4e-05 23.2 0.6 0.003 17.1 0.0 2.9 2 1 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family Sulfotransfer_3 PF13469.6 GAX28102.1 - 4.7e-22 79.4 0.9 1.3e-20 74.7 0.2 2.9 2 2 0 2 2 2 1 Sulfotransferase family TPR_11 PF13414.6 GAX28102.1 - 0.00098 18.8 0.0 0.1 12.3 0.0 2.9 3 0 0 3 3 3 1 TPR repeat Sulfotransfer_1 PF00685.27 GAX28102.1 - 0.001 18.6 0.1 0.0059 16.1 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase domain TPR_2 PF07719.17 GAX28102.1 - 0.0015 18.5 0.0 0.77 10.0 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28102.1 - 0.049 13.5 0.0 3.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 GAX28102.1 - 0.061 12.2 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 GAX28102.1 - 0.18 12.5 0.0 1.2 9.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Chloroa_b-bind PF00504.21 GAX28104.1 - 1.2e-38 133.2 0.0 1.9e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SHQ1 PF04925.15 GAX28106.1 - 2.3e-39 134.7 2.4 4.2e-39 133.9 2.4 1.4 1 0 0 1 1 1 1 SHQ1 protein CENP-B_dimeris PF09026.10 GAX28106.1 - 0.042 14.2 4.6 0.094 13.1 4.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CS PF04969.16 GAX28106.1 - 0.11 13.5 0.0 0.23 12.5 0.0 1.6 1 0 0 1 1 1 0 CS domain zf-MYND PF01753.18 GAX28107.1 - 1e-07 31.9 20.3 1.5e-07 31.4 20.3 1.2 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 GAX28107.1 - 2.3 6.0 6.1 2.6 5.8 6.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PX PF00787.24 GAX28110.1 - 6.9e-17 61.5 0.0 2.1e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 PX domain DUF2072 PF09845.9 GAX28110.1 - 0.17 12.1 3.6 0.56 10.5 3.6 1.9 1 0 0 1 1 1 0 Zn-ribbon containing protein EIIBC-GUT_N PF03612.14 GAX28110.1 - 8.9 6.0 9.8 1.2 8.9 4.9 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Snf7 PF03357.21 GAX28111.1 - 2.4e-11 43.6 12.3 2.9e-11 43.3 12.3 1.1 1 0 0 1 1 1 1 Snf7 DUF1771 PF08590.10 GAX28111.1 - 0.012 16.0 4.4 0.02 15.2 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DUF1810 PF08837.11 GAX28111.1 - 0.057 13.2 0.4 0.083 12.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) DMSP_lyase PF16867.5 GAX28111.1 - 0.23 11.1 0.9 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase SMBP PF16785.5 GAX28111.1 - 0.34 11.2 5.5 0.73 10.1 5.1 1.8 1 1 0 1 1 1 0 Small metal-binding protein AAA_13 PF13166.6 GAX28111.1 - 0.36 9.4 5.7 0.72 8.4 5.7 1.4 1 1 0 1 1 1 0 AAA domain Mt_ATP-synt_D PF05873.12 GAX28111.1 - 0.92 9.4 4.5 4.1 7.2 0.1 2.4 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF948 PF06103.11 GAX28111.1 - 3.1 8.1 6.0 6.6 7.1 2.1 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HMG_box PF00505.19 GAX28113.1 - 4.6e-07 30.2 12.4 0.0011 19.4 0.1 3.4 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX28113.1 - 2.2e-06 28.2 4.0 2.2e-06 28.2 4.0 3.2 1 1 1 2 2 2 1 HMG-box domain Strep_SA_rep PF06696.11 GAX28113.1 - 0.054 13.5 5.3 0.38 10.8 0.6 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat YaeQ PF07152.12 GAX28113.1 - 0.099 12.2 2.4 0.17 11.4 2.4 1.3 1 0 0 1 1 1 0 YaeQ protein YABBY PF04690.13 GAX28113.1 - 0.26 11.9 0.1 0.26 11.9 0.1 2.1 2 0 0 2 2 2 0 YABBY protein Comm PF15957.5 GAX28113.1 - 0.35 11.2 1.8 2.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Commissureless NAD_binding_10 PF13460.6 GAX28114.1 - 1.3e-22 80.6 0.5 2.1e-22 79.9 0.5 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAX28114.1 - 0.00014 21.5 0.3 0.00023 20.8 0.3 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAX28114.1 - 0.00017 21.1 0.1 0.00087 18.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAX28114.1 - 0.00024 21.4 0.7 0.0027 18.0 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAX28114.1 - 0.00037 20.0 0.1 0.00068 19.2 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 GAX28114.1 - 0.00078 20.0 0.0 0.002 18.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 GAX28114.1 - 0.036 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.19 GAX28114.1 - 0.04 13.2 0.1 0.097 12.0 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 GAX28114.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 GAX28114.1 - 0.073 12.2 0.1 8.3 5.4 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_7 PF13241.6 GAX28114.1 - 0.099 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Vac14_Fig4_bd PF11916.8 GAX28115.1 - 9.9e-70 233.8 4.9 9.9e-70 233.8 4.9 2.7 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 GAX28115.1 - 1.7e-44 150.4 0.0 1.1e-37 128.5 0.0 4.5 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAX28115.1 - 5.8e-15 54.1 6.8 1.4e-05 24.9 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 GAX28115.1 - 1.8e-11 44.3 3.7 3.2e-05 24.3 0.0 4.6 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 GAX28115.1 - 2.1e-11 44.1 0.9 0.0008 19.5 0.0 5.0 1 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAX28115.1 - 3.6e-08 33.7 2.2 0.17 12.3 0.0 5.4 3 2 3 6 6 6 3 HEAT repeats CLASP_N PF12348.8 GAX28115.1 - 5.6e-06 26.1 1.9 0.22 11.0 0.0 4.7 3 1 1 5 5 5 2 CLASP N terminal Tti2 PF10521.9 GAX28115.1 - 6.1e-06 26.0 5.9 5.9e-05 22.7 0.0 4.6 2 2 2 4 4 4 1 Tti2 family RTP1_C1 PF10363.9 GAX28115.1 - 0.0084 16.3 2.3 0.64 10.2 0.1 4.0 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 GAX28115.1 - 0.026 14.6 1.2 0.39 10.8 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ParcG PF10274.9 GAX28115.1 - 0.042 14.0 0.6 5.1 7.2 0.0 3.1 2 1 1 3 3 3 0 Parkin co-regulated protein MMS19_C PF12460.8 GAX28115.1 - 0.053 12.6 0.0 0.053 12.6 0.0 4.1 4 1 0 5 5 5 0 RNAPII transcription regulator C-terminal V-ATPase_H_N PF03224.14 GAX28115.1 - 0.061 12.6 2.4 0.27 10.5 0.3 2.6 2 1 0 2 2 2 0 V-ATPase subunit H SF3A2 PF16835.5 GAX28116.1 - 1e-31 109.1 0.0 2.1e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 GAX28116.1 - 9.9e-07 29.0 1.1 2.2e-06 27.8 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 GAX28116.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein FeThRed_B PF02943.15 GAX28117.1 - 1.2e-36 125.0 4.3 1.7e-36 124.5 4.3 1.2 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain ADK PF00406.22 GAX28118.1 - 4.4e-50 169.7 0.0 5.9e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAX28118.1 - 3.8e-25 88.9 0.2 1.8e-24 86.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 GAX28118.1 - 4.1e-07 30.6 0.2 1.2e-05 25.9 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX28118.1 - 2.1e-05 24.7 0.4 0.069 13.3 0.0 2.8 1 1 1 2 2 2 2 AAA domain Hydin_ADK PF17213.3 GAX28118.1 - 0.00096 19.5 0.8 0.13 12.5 0.1 2.4 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 GAX28118.1 - 0.0038 17.0 0.1 0.0093 15.7 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase Zeta_toxin PF06414.12 GAX28118.1 - 0.0063 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 GAX28118.1 - 0.012 15.3 0.1 2.6 7.7 0.0 2.5 1 1 1 2 2 2 0 Thymidylate kinase ADK_lid PF05191.14 GAX28118.1 - 0.033 14.2 0.0 0.08 12.9 0.0 1.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid dNK PF01712.19 GAX28118.1 - 0.075 12.9 0.9 12 5.6 0.1 2.5 2 1 1 3 3 3 0 Deoxynucleoside kinase NUDIX PF00293.28 GAX28118.1 - 0.08 13.0 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 NUDIX domain dCMP_cyt_deam_1 PF00383.23 GAX28119.1 - 3.6e-13 49.2 0.2 5.9e-13 48.6 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAX28119.1 - 1.5e-05 24.8 0.1 1.9e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase HMG_box PF00505.19 GAX28120.1 - 1.4e-11 44.6 7.4 1.2e-07 32.0 3.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX28120.1 - 4.4e-07 30.4 3.4 0.00083 19.9 2.3 2.6 2 0 0 2 2 2 2 HMG-box domain PPL5 PF18168.1 GAX28120.1 - 0.83 8.9 6.8 1.3 8.2 6.8 1.4 1 0 0 1 1 1 0 Prim-pol family 5 YABBY PF04690.13 GAX28120.1 - 1.3 9.6 6.7 0.18 12.4 0.5 2.3 1 1 0 2 2 2 0 YABBY protein NOA36 PF06524.12 GAX28120.1 - 1.6 7.9 20.6 0.11 11.9 15.3 1.6 2 0 0 2 2 2 0 NOA36 protein Pox_Ag35 PF03286.14 GAX28120.1 - 3.8 7.3 24.7 0.24 11.1 13.3 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CHORD PF04968.12 GAX28121.1 - 1e-18 67.8 7.1 1.9e-18 66.9 7.1 1.4 1 0 0 1 1 1 1 CHORD Pex2_Pex12 PF04757.14 GAX28123.1 - 1.4e-11 44.4 1.4 1.9e-11 44.0 1.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region ETC_C1_NDUFA5 PF04716.14 GAX28123.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 ETC complex I subunit conserved region Pkinase_Tyr PF07714.17 GAX28124.1 - 4e-57 193.5 0.0 6e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX28124.1 - 7.2e-50 169.8 0.0 1.3e-49 169.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GAX28124.1 - 5.9e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAX28124.1 - 0.00013 20.9 0.4 0.00023 20.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAX28124.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX28124.1 - 0.026 14.4 0.0 0.069 13.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Methyltrn_RNA_3 PF02598.17 GAX28127.1 - 1.4e-95 320.1 0.0 1.9e-95 319.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase Sporozoite_P67 PF05642.11 GAX28127.1 - 0.44 8.6 12.5 0.26 9.3 7.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 GAX28127.1 - 9 6.1 14.8 38 4.1 11.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Glyco_trans_1_2 PF13524.6 GAX28128.1 - 2.8e-09 37.2 0.0 6.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_C1 PF00112.23 GAX28129.1 - 5.4e-52 177.0 0.1 7.4e-52 176.6 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX28129.1 - 5.8e-09 36.3 2.1 1e-08 35.5 2.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAX28129.1 - 0.002 17.0 0.8 1.1 7.9 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.6 GAX28129.1 - 0.091 13.3 0.5 0.17 12.5 0.4 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family SUIM_assoc PF16619.5 GAX28129.1 - 0.48 10.5 3.3 1 9.5 3.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CbiX PF01903.17 GAX28130.1 - 5.9e-21 74.8 0.3 8.6e-21 74.3 0.3 1.2 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 GAX28130.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Cnd1 PF12717.7 GAX28131.1 - 3.3e-24 85.7 5.6 4.7e-12 46.3 0.0 6.0 5 1 1 6 6 6 4 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAX28131.1 - 8.3e-11 41.2 4.6 0.018 15.3 0.1 7.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 GAX28131.1 - 0.0025 18.3 5.9 4.7 7.8 0.1 5.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 GAX28131.1 - 0.0029 18.0 5.2 0.16 12.4 0.2 5.1 3 2 3 6 6 6 3 HEAT repeats Cnd3 PF12719.7 GAX28131.1 - 0.0074 15.5 4.8 0.028 13.6 0.1 3.6 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 GAX28131.1 - 0.074 13.4 4.2 0.31 11.4 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Glutaminase PF04960.15 GAX28132.1 - 1.9e-93 312.8 0.0 3.4e-93 311.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminase TerB PF05099.13 GAX28132.1 - 0.00014 21.8 0.2 0.0003 20.8 0.2 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 GAX28132.1 - 0.027 14.8 0.0 0.098 13.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Peptidase_M15_2 PF05951.13 GAX28132.1 - 0.12 12.0 0.3 2.7 7.7 0.0 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF882) Glyco_hydro_125 PF06824.11 GAX28133.1 - 1.7e-87 294.0 0.0 2.9e-87 293.3 0.0 1.3 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) COMP PF11598.8 GAX28133.1 - 0.12 12.9 0.5 0.32 11.5 0.5 1.7 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Glyco_hydro_125 PF06824.11 GAX28134.1 - 1.4e-115 386.6 0.0 1.9e-115 386.1 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) L27_1 PF09058.10 GAX28134.1 - 0.076 13.0 0.2 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 L27_1 TssO PF17561.2 GAX28134.1 - 0.24 11.5 1.6 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO HMG_box PF00505.19 GAX28135.1 - 2.3e-12 47.1 0.3 1.9e-06 28.2 0.2 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX28135.1 - 8e-06 26.4 0.4 0.057 14.0 0.1 2.5 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.13 GAX28135.1 - 0.039 14.5 1.9 0.12 13.0 0.1 2.3 2 0 0 2 2 2 0 YABBY protein adh_short PF00106.25 GAX28136.1 - 1.9e-29 102.6 0.1 2e-24 86.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28136.1 - 4.7e-17 62.3 0.1 8.8e-17 61.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX28136.1 - 1.4e-10 41.3 0.1 2.2e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX28136.1 - 0.0019 17.4 0.0 0.0026 16.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAX28136.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAX28137.1 - 2.1e-32 112.2 0.0 3e-24 85.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28137.1 - 9.6e-17 61.3 0.1 2.6e-14 53.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX28137.1 - 2.1e-10 40.8 0.1 3.3e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX28137.1 - 0.031 13.4 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAX28137.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 GAX28137.1 - 0.18 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAX28138.1 - 6.6e-28 97.5 0.6 7.5e-23 81.0 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28138.1 - 2.6e-16 59.9 0.1 2.9e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX28138.1 - 3.5e-09 36.8 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX28138.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UNC119_bdg PF15435.6 GAX28138.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue adh_short PF00106.25 GAX28139.1 - 7.8e-30 103.8 0.0 2.7e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28139.1 - 4e-17 62.6 0.1 9e-16 58.1 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX28139.1 - 5.5e-11 42.7 0.1 8.3e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAX28139.1 - 0.00083 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAX28139.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 GAX28139.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 GAX28139.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAR2 PF05282.11 GAX28140.1 - 2e-17 63.7 2.7 4.3e-16 59.3 2.2 2.3 1 1 0 1 1 1 1 AAR2 protein RNA_pol_3_Rpc31 PF11705.8 GAX28140.1 - 0.018 15.3 4.0 0.031 14.5 4.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2172 PF09940.9 GAX28140.1 - 0.023 15.1 0.6 0.08 13.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2172) Ric8 PF10165.9 GAX28140.1 - 0.033 13.2 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Ribonuc_red_2_N PF08471.10 GAX28140.1 - 0.043 14.0 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase Fcf1 PF04900.12 GAX28141.1 - 2.8e-28 98.2 2.7 6.1e-28 97.1 2.7 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 GAX28141.1 - 3e-12 46.9 0.0 1.4e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 PIN like domain DUF1175 PF06672.11 GAX28141.1 - 0.033 13.9 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) DUF1972 PF09314.11 GAX28141.1 - 0.037 13.6 0.1 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) TackOD1 PF18551.1 GAX28142.1 - 0.053 13.2 0.9 0.1 12.3 0.2 1.7 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Rab5ip PF07019.12 GAX28143.1 - 1.5e-16 60.7 7.9 3e-16 59.8 7.9 1.5 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) zf-RING_2 PF13639.6 GAX28143.1 - 2e-05 24.8 0.8 4.6e-05 23.7 0.8 1.7 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 GAX28143.1 - 0.00013 22.0 0.4 0.00013 22.0 0.4 1.8 2 0 0 2 2 2 1 RING-variant domain zf-RING_11 PF17123.5 GAX28143.1 - 0.062 13.1 4.2 0.31 10.8 4.2 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 GAX28144.1 - 4.8e-10 39.6 16.5 9e-10 38.7 16.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAX28144.1 - 2.1e-07 31.1 10.6 4.3e-07 30.1 10.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAX28144.1 - 1.1e-06 28.3 8.0 2.3e-06 27.3 8.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAX28144.1 - 1.6e-06 27.8 13.9 3.3e-06 26.8 13.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX28144.1 - 8.3e-05 22.5 11.8 0.00015 21.7 11.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAX28144.1 - 0.0013 18.6 11.2 0.003 17.4 11.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX28144.1 - 0.002 18.1 6.8 0.002 18.1 6.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAX28144.1 - 0.0082 16.2 11.7 0.021 14.8 11.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX28144.1 - 0.078 12.6 14.1 0.14 11.8 14.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type EMC3_TMCO1 PF01956.16 GAX28144.1 - 0.18 11.5 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like zf-C3HC4_3 PF13920.6 GAX28144.1 - 0.23 11.3 17.9 0.45 10.4 17.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.28 GAX28145.1 - 4.2e-21 74.9 0.0 6.2e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain IRK_C PF17655.1 GAX28146.1 - 9.6e-20 70.9 0.0 2.8e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 GAX28146.1 - 2.4e-09 37.1 11.0 6.4e-08 32.5 11.0 2.2 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 GAX28146.1 - 0.0023 17.9 9.4 0.0055 16.7 9.4 1.7 1 0 0 1 1 1 1 Ion channel Fer2 PF00111.27 GAX28147.1 - 5.5e-07 29.5 0.8 7.9e-07 28.9 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 GAX28147.1 - 5.4e-05 23.2 0.2 6.8e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 GAX28147.1 - 0.0011 18.9 1.8 0.0039 17.2 1.8 1.7 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zip PF02535.22 GAX28148.1 - 5.7e-13 48.8 21.0 4.8e-10 39.2 12.4 2.5 1 1 2 3 3 3 2 ZIP Zinc transporter Fis1_TPR_C PF14853.6 GAX28149.1 - 1.1e-07 31.8 0.4 2.5e-07 30.7 0.4 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 GAX28149.1 - 0.00012 21.7 0.7 0.00022 20.8 0.0 1.8 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 GAX28149.1 - 0.00013 22.4 0.1 0.00013 22.4 0.1 2.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28149.1 - 0.0017 18.3 3.2 0.0027 17.7 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX28149.1 - 0.0055 17.3 0.2 0.0055 17.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX28149.1 - 0.0064 17.0 0.9 0.0064 17.0 0.9 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX28149.1 - 0.0088 16.8 1.1 0.0088 16.8 1.1 2.7 2 2 1 3 3 3 1 Tetratricopeptide repeat DUF883 PF05957.13 GAX28149.1 - 0.017 15.7 1.8 0.017 15.7 1.8 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ANAPC3 PF12895.7 GAX28149.1 - 0.049 13.9 0.9 0.049 13.9 0.9 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAX28149.1 - 0.54 10.9 14.4 0.6 10.8 9.4 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAX28149.1 - 0.81 9.8 12.4 5.6 7.1 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Metal_resist PF13801.6 GAX28149.1 - 1.6 8.9 14.9 1.7 8.9 6.5 2.4 2 1 0 2 2 2 0 Heavy-metal resistance Aa_trans PF01490.18 GAX28150.1 - 1.1e-11 44.1 1.5 3.4e-09 35.9 0.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein CLN6 PF15156.6 GAX28150.1 - 0.11 11.8 1.1 0.35 10.1 0.1 2.0 1 1 1 2 2 2 0 Ceroid-lipofuscinosis neuronal protein 6 KIX PF02172.16 GAX28151.1 - 0.034 14.4 0.4 0.07 13.4 0.1 1.6 2 0 0 2 2 2 0 KIX domain Mak10 PF04112.13 GAX28152.1 - 1.7e-16 60.2 0.2 4.3e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_L1 PF00687.21 GAX28153.1 - 3.4e-40 138.0 0.6 3.4e-40 138.0 0.6 2.9 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family PPR_2 PF13041.6 GAX28154.1 - 1.7e-18 66.5 0.0 4.5e-05 23.5 0.0 8.1 9 1 1 10 10 10 2 PPR repeat family PPR_3 PF13812.6 GAX28154.1 - 2e-11 43.8 0.0 0.0024 17.9 0.0 6.4 5 1 2 7 7 7 3 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX28154.1 - 5.8e-09 35.6 6.0 0.0011 18.4 0.1 5.3 1 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAX28154.1 - 8e-09 35.1 2.1 0.99 9.2 0.0 7.6 9 1 0 9 9 9 2 PPR repeat PPR PF01535.20 GAX28154.1 - 0.0041 17.3 3.1 7.8 7.0 0.1 6.2 6 0 0 6 6 6 1 PPR repeat Dak2 PF02734.17 GAX28154.1 - 1.2 9.0 3.1 59 3.5 0.1 3.2 3 0 0 3 3 3 0 DAK2 domain GCS PF03074.16 GAX28155.1 - 2.3e-158 527.4 0.0 3.4e-158 526.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase Nuc_sug_transp PF04142.15 GAX28156.1 - 2.7e-113 378.3 18.0 3.3e-113 378.0 18.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAX28156.1 - 2.6e-09 36.7 15.3 5.7e-09 35.6 15.3 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAX28156.1 - 6.1e-08 32.9 33.7 1.3e-06 28.6 10.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAX28156.1 - 1.1e-06 28.1 6.0 1.1e-06 28.1 6.0 2.4 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 GAX28156.1 - 0.00011 21.2 2.8 0.00011 21.2 2.8 2.0 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF202 PF02656.15 GAX28156.1 - 0.013 15.9 6.4 2 8.9 0.0 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Multi_Drug_Res PF00893.19 GAX28156.1 - 0.016 15.9 1.2 0.016 15.9 1.2 3.0 2 2 1 3 3 3 0 Small Multidrug Resistance protein Halogen_Hydrol PF10112.9 GAX28156.1 - 0.044 13.8 0.4 2 8.4 0.3 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TMEM234 PF10639.9 GAX28156.1 - 1.1 9.3 8.4 0.24 11.5 0.8 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 PseudoU_synth_1 PF01416.20 GAX28157.1 - 1e-29 103.2 0.0 1.4e-27 96.3 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF5565 PF17720.1 GAX28157.1 - 0.0081 15.1 0.2 0.078 11.8 0.0 2.5 2 1 1 3 3 3 1 Family of unknown function (DUF5565) FBPase PF00316.20 GAX28158.1 - 7.2e-62 208.2 0.1 2.3e-61 206.6 0.1 1.7 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain PDZ_6 PF17820.1 GAX28159.1 - 9.8e-07 28.5 0.1 2.9e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX28159.1 - 0.0015 18.9 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Rhodanese PF00581.20 GAX28160.1 - 1.4e-19 70.6 0.0 4.9e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Ecm29 PF13001.7 GAX28160.1 - 0.11 11.2 0.0 0.28 9.8 0.0 1.6 2 0 0 2 2 2 0 Proteasome stabiliser HSF_DNA-bind PF00447.17 GAX28161.1 - 3e-21 75.8 0.1 4.5e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Helicase_C_2 PF13307.6 GAX28162.1 - 6.7e-51 172.8 0.0 5.9e-50 169.8 0.0 2.3 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAX28162.1 - 6.2e-46 156.2 0.0 1.2e-45 155.2 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 zf-C3HC4_2 PF13923.6 GAX28162.1 - 2.9e-08 33.4 12.5 7.8e-08 32.0 12.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX28162.1 - 4.1e-08 33.0 8.6 4.1e-08 33.0 8.6 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 GAX28162.1 - 9.3e-07 29.0 0.1 0.00059 19.9 0.0 2.7 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 GAX28162.1 - 5.1e-06 26.7 13.6 2.2e-05 24.7 13.6 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAX28162.1 - 8.3e-06 25.6 11.5 2.5e-05 24.0 11.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX28162.1 - 9.7e-05 22.1 12.1 0.00026 20.8 11.4 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAX28162.1 - 0.00053 20.1 14.5 0.0026 17.9 13.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAX28162.1 - 0.00099 19.1 8.9 0.0034 17.4 8.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAX28162.1 - 0.0013 18.7 9.7 0.0034 17.3 9.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 GAX28162.1 - 0.0016 18.2 0.1 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAX28162.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-rbx1 PF12678.7 GAX28162.1 - 0.034 14.4 12.1 0.015 15.6 8.8 2.3 2 0 0 2 2 1 0 RING-H2 zinc finger domain HBB PF06777.11 GAX28162.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Helical and beta-bridge domain zf-RING_4 PF14570.6 GAX28162.1 - 0.17 11.7 9.0 0.71 9.7 9.0 2.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 GAX28162.1 - 0.31 11.1 4.6 0.75 9.9 4.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 GAX28162.1 - 4 7.6 8.8 14 5.9 8.8 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 TPR_12 PF13424.6 GAX28163.1 - 4.5e-32 110.2 0.0 2.6e-10 40.4 0.0 4.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28163.1 - 1.1e-23 81.4 0.0 0.00079 19.4 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28163.1 - 1.2e-20 72.4 0.0 0.0018 18.0 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAX28163.1 - 1e-17 62.8 0.0 0.012 15.7 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAX28163.1 - 2.6e-17 62.1 0.0 0.013 15.4 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAX28163.1 - 2e-13 49.3 0.0 0.012 15.6 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX28163.1 - 2.9e-09 37.0 0.0 0.58 11.1 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX28163.1 - 1.4e-08 34.5 0.0 1.1e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 GAX28163.1 - 2.3e-08 34.5 0.0 0.21 12.3 0.0 5.4 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX28163.1 - 1.3e-07 31.8 0.0 8.8 7.2 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX28163.1 - 5.9e-06 25.9 0.0 0.42 10.3 0.0 4.7 5 1 1 6 6 6 2 TPR repeat TPR_4 PF07721.14 GAX28163.1 - 0.00033 21.0 0.0 2.2 9.2 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX28163.1 - 0.00046 20.4 0.0 0.32 11.3 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAX28163.1 - 0.00047 20.6 0.0 1.6 9.3 0.0 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX28163.1 - 0.0059 16.7 0.0 6.1 7.1 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX28163.1 - 0.0099 16.2 0.0 17 6.1 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAX28163.1 - 0.025 13.8 0.0 0.11 11.7 0.0 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Paf67 PF10255.9 GAX28163.1 - 0.077 12.0 0.0 6 5.8 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 Lipocalin_2 PF08212.12 GAX28164.1 - 3.3e-05 23.9 0.0 0.0011 18.9 0.1 2.3 2 1 0 2 2 2 2 Lipocalin-like domain AAA_2 PF07724.14 GAX28165.1 - 2.7e-54 183.9 0.1 3.6e-53 180.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAX28165.1 - 2e-33 114.4 4.1 5.5e-33 113.0 0.1 3.2 1 1 2 3 3 3 1 AAA lid domain ClpB_D2-small PF10431.9 GAX28165.1 - 1.4e-26 92.4 0.5 9.3e-26 89.7 0.1 2.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GAX28165.1 - 1.7e-24 86.8 0.4 2.9e-12 47.1 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX28165.1 - 8.3e-16 58.2 0.0 4.1e-10 39.8 0.0 3.8 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX28165.1 - 4.8e-12 46.6 1.3 0.00019 21.9 0.0 4.8 4 1 0 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 GAX28165.1 - 2.3e-08 33.9 0.0 4.3e-05 23.3 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 GAX28165.1 - 2.7e-08 34.2 2.4 0.037 14.3 0.0 5.4 4 2 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 GAX28165.1 - 6.8e-06 25.9 0.0 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 GAX28165.1 - 1.1e-05 26.0 0.0 0.29 11.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 GAX28165.1 - 1.2e-05 24.8 0.0 0.0061 16.0 0.1 3.5 2 1 0 2 2 2 1 Bacterial TniB protein RuvB_N PF05496.12 GAX28165.1 - 2.7e-05 24.0 0.2 1.9 8.2 0.0 4.3 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 GAX28165.1 - 4.2e-05 23.6 0.3 4.8 7.0 0.0 4.3 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 GAX28165.1 - 9.5e-05 21.9 0.1 0.88 8.9 0.0 3.2 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAX28165.1 - 0.00018 21.1 0.0 0.094 12.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Clp_N PF02861.20 GAX28165.1 - 0.00036 20.6 0.4 0.0085 16.2 0.0 2.8 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component AAA_14 PF13173.6 GAX28165.1 - 0.00043 20.3 0.0 1.6 8.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 GAX28165.1 - 0.00075 19.5 0.2 0.27 11.1 0.0 3.2 4 0 0 4 4 3 1 NACHT domain Roc PF08477.13 GAX28165.1 - 0.00099 19.3 0.0 0.91 9.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 GAX28165.1 - 0.0013 19.1 0.0 1.7 9.1 0.0 3.0 2 0 0 2 2 2 1 RNA helicase ResIII PF04851.15 GAX28165.1 - 0.0014 18.6 0.0 0.25 11.4 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit TsaE PF02367.17 GAX28165.1 - 0.0022 18.0 0.0 3.7 7.6 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAX28165.1 - 0.0023 17.7 0.0 0.95 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX28165.1 - 0.0062 16.1 0.6 0.6 9.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 GAX28165.1 - 0.0065 16.7 0.1 7.7 6.7 0.0 4.0 4 0 0 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 GAX28165.1 - 0.011 15.6 0.0 2.6 7.9 0.0 3.0 3 0 0 3 3 2 0 RsgA GTPase Torsin PF06309.11 GAX28165.1 - 0.013 15.6 0.0 0.098 12.8 0.0 2.2 2 0 0 2 2 2 0 Torsin ABC_tran PF00005.27 GAX28165.1 - 0.016 15.7 0.0 0.7 10.4 0.0 3.0 3 0 0 3 3 2 0 ABC transporter AAA_33 PF13671.6 GAX28165.1 - 0.032 14.4 0.0 24 5.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 GAX28165.1 - 0.04 13.2 0.0 13 5.0 0.0 2.9 2 0 0 2 2 2 0 Zeta toxin TIP49 PF06068.13 GAX28165.1 - 0.051 12.8 0.0 0.52 9.5 0.0 2.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_19 PF13245.6 GAX28165.1 - 0.067 13.5 0.1 1.5 9.1 0.1 3.0 3 1 0 3 3 2 0 AAA domain AAA_3 PF07726.11 GAX28165.1 - 0.077 12.9 0.0 15 5.4 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 GAX28165.1 - 0.15 11.8 0.0 1 9.1 0.0 2.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein LUC7 PF03194.15 GAX28165.1 - 0.65 9.6 3.5 1.4 8.5 3.5 1.5 1 0 0 1 1 1 0 LUC7 N_terminus ABC_tran_CTD PF16326.5 GAX28165.1 - 1.2 9.5 14.9 0.069 13.4 4.4 3.5 1 1 1 3 3 3 0 ABC transporter C-terminal domain AAA_23 PF13476.6 GAX28165.1 - 2.3 8.7 11.5 22 5.5 0.0 3.5 2 1 0 2 2 2 0 AAA domain ADIP PF11559.8 GAX28165.1 - 3.7 7.6 7.0 1.2 9.2 3.1 2.2 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding VHL PF01847.16 GAX28167.1 - 0.016 15.1 0.8 0.3 11.0 0.1 3.0 2 1 0 2 2 2 0 VHL beta domain SET PF00856.28 GAX28168.1 - 4.1e-12 46.8 0.6 1.2e-10 42.0 0.1 2.4 2 0 0 2 2 2 1 SET domain CpXC PF14353.6 GAX28168.1 - 0.0017 18.4 4.2 0.015 15.4 0.4 3.0 3 0 0 3 3 3 1 CpXC protein PHD_Oberon PF07227.11 GAX28168.1 - 0.05 13.5 4.0 0.1 12.5 4.0 1.5 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein PAP_fibrillin PF04755.12 GAX28169.1 - 0.003 17.5 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 PAP_fibrillin Pkinase PF00069.25 GAX28170.1 - 1.8e-42 145.5 0.0 3e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX28170.1 - 2.4e-26 92.6 0.0 4.4e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX28170.1 - 0.00014 21.8 0.3 0.0041 17.1 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAX28170.1 - 0.0092 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAX28170.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HisG_C PF08029.11 GAX28170.1 - 0.16 12.2 0.1 16 5.8 0.0 2.6 2 0 0 2 2 2 0 HisG, C-terminal domain DUF3349 PF11829.8 GAX28170.1 - 0.57 11.0 2.4 99 3.8 0.6 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3349) ubiquitin PF00240.23 GAX28171.1 - 9.7e-34 115.0 0.4 2.3e-33 113.8 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin family Sod_Ni PF09055.11 GAX28171.1 - 7.4e-31 107.4 1.1 1.2e-30 106.7 1.1 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Rad60-SLD PF11976.8 GAX28171.1 - 4.9e-16 58.3 0.7 1e-15 57.3 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX28171.1 - 3.3e-05 24.3 0.1 0.00014 22.2 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX28171.1 - 0.0056 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX28171.1 - 0.015 15.4 0.3 0.063 13.4 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAX28171.1 - 0.018 15.4 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 GAX28171.1 - 0.033 14.7 0.1 0.083 13.5 0.1 1.9 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX28171.1 - 0.41 10.7 3.8 14 5.8 0.0 3.1 3 1 0 3 3 3 0 Ubiquitin-like domain Glyco_transf_49 PF13896.6 GAX28172.1 - 2.2e-35 122.6 0.0 7.6e-33 114.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAX28172.1 - 0.029 14.2 0.0 0.091 12.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAX28172.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_49 PF13896.6 GAX28173.1 - 7e-39 134.1 0.1 1.3e-30 107.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.9 GAX28173.1 - 0.0058 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAX28173.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Proteasome PF00227.26 GAX28174.1 - 2.2e-10 40.3 0.0 3.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Cyt-b5 PF00173.28 GAX28175.1 - 1.5e-09 37.8 0.1 2.1e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2121 PF09894.9 GAX28175.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) TPR_12 PF13424.6 GAX28176.1 - 1.1e-71 237.0 21.8 7.5e-16 58.2 0.0 8.8 5 2 5 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 GAX28176.1 - 2e-40 135.6 25.2 0.00015 21.6 0.4 12.8 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28176.1 - 1.4e-27 93.5 18.6 0.0008 19.3 0.1 10.8 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28176.1 - 1.6e-25 87.9 16.4 0.00032 20.4 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAX28176.1 - 1.9e-19 68.2 7.5 0.0091 16.1 0.0 10.1 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX28176.1 - 5.1e-11 42.5 16.4 0.0019 17.6 0.1 4.3 2 2 1 4 4 4 4 MalT-like TPR region TPR_7 PF13176.6 GAX28176.1 - 1.7e-10 40.2 18.4 0.12 12.5 0.1 10.0 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAX28176.1 - 1.5e-07 31.6 9.5 16 6.4 0.1 9.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX28176.1 - 2.7e-07 31.0 9.7 0.58 10.7 0.0 6.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAX28176.1 - 1.9e-06 27.9 4.3 37 5.0 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX28176.1 - 7.7e-06 26.5 24.4 0.32 11.7 0.1 7.5 6 2 1 7 7 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX28176.1 - 0.00049 19.5 1.9 2.3 7.8 0.0 5.3 6 0 0 6 6 6 1 SHNi-TPR Fis1_TPR_C PF14853.6 GAX28176.1 - 0.00075 19.5 2.6 19 5.4 0.4 4.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 GAX28176.1 - 0.017 15.1 3.3 0.15 12.1 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_11 PF13414.6 GAX28176.1 - 0.19 11.5 15.2 4.4 7.1 0.0 7.7 7 2 1 8 8 8 0 TPR repeat TPR_9 PF13371.6 GAX28176.1 - 0.94 9.7 8.7 5.9 7.1 0.1 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAX28176.1 - 1.4 9.0 3.1 26 5.0 0.1 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 GAX28178.1 - 3.4e-34 116.8 25.6 0.00078 19.9 0.1 18.0 18 2 2 20 20 17 7 HEAT-like repeat HEAT PF02985.22 GAX28178.1 - 1.9e-33 111.6 23.6 0.0015 18.6 0.0 17.8 18 0 0 18 18 18 8 HEAT repeat HEAT_2 PF13646.6 GAX28178.1 - 2.8e-26 91.7 37.2 4.2e-06 27.1 0.0 15.9 12 4 4 17 17 17 8 HEAT repeats Cnd1 PF12717.7 GAX28178.1 - 4.3e-21 75.6 0.4 0.0046 17.0 0.0 10.5 7 2 2 11 11 10 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAX28178.1 - 9.2e-13 48.6 0.0 0.12 13.0 0.0 8.2 9 1 2 11 11 9 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAX28178.1 - 8.3e-11 41.9 0.1 0.00027 20.6 0.0 7.4 7 1 1 8 8 8 2 CLASP N terminal Adaptin_N PF01602.20 GAX28178.1 - 1.4e-10 40.3 8.9 0.00012 20.8 0.1 7.0 6 1 0 6 6 6 2 Adaptin N terminal region ParcG PF10274.9 GAX28178.1 - 1.4e-08 35.1 1.3 0.93 9.6 0.0 7.6 9 1 1 10 10 10 2 Parkin co-regulated protein UME PF08064.13 GAX28178.1 - 1.7e-08 34.3 3.1 1.1 9.2 0.0 7.9 6 1 1 8 8 7 1 UME (NUC010) domain TIP120 PF08623.10 GAX28178.1 - 3.2e-05 23.7 1.1 0.016 14.9 0.0 4.0 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) Arm PF00514.23 GAX28178.1 - 5.9e-05 23.0 14.7 2.1 8.5 0.0 10.8 14 0 0 14 14 13 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 GAX28178.1 - 0.0061 16.4 0.1 2.2 8.3 0.1 5.0 6 0 0 6 6 5 1 Domain of unknown function (DUF3437) MMS19_C PF12460.8 GAX28178.1 - 0.023 13.8 29.6 2.4 7.2 0.6 9.4 9 2 2 11 11 11 0 RNAPII transcription regulator C-terminal ADSL_C PF10397.9 GAX28178.1 - 0.041 14.4 0.3 2.2 8.9 0.0 3.8 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus DUF3385 PF11865.8 GAX28178.1 - 0.054 13.4 0.7 15 5.5 0.0 5.1 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) EcoRI_methylase PF13651.6 GAX28178.1 - 0.061 12.5 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI DUF4286 PF14114.6 GAX28178.1 - 0.072 13.6 0.1 0.21 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) SpoU_methylase PF00588.19 GAX28179.1 - 7.9e-30 103.9 0.0 2e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAX28179.1 - 0.001 19.3 0.1 0.0058 16.9 0.0 2.4 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding V-SNARE_C PF12352.8 GAX28180.1 - 2.5e-13 50.1 5.2 5.7e-13 48.9 5.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 GAX28180.1 - 2.5e-08 34.2 11.5 1.4e-07 31.8 7.1 3.2 1 1 1 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 GAX28180.1 - 4.3e-05 23.4 2.9 0.00016 21.5 0.0 2.8 1 1 2 3 3 3 1 Sec20 Nucleos_tra2_N PF01773.20 GAX28180.1 - 0.052 14.2 1.4 0.092 13.4 1.4 1.4 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus AbiJ_NTD5 PF18865.1 GAX28180.1 - 0.056 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 DUF3552 PF12072.8 GAX28180.1 - 0.69 9.3 11.3 1.5 8.2 11.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2564 PF10819.8 GAX28180.1 - 0.89 10.0 6.2 0.77 10.2 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) V-ATPase_G_2 PF16999.5 GAX28180.1 - 1.2 9.6 8.3 2.3 8.7 0.8 2.5 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit FadA PF09403.10 GAX28180.1 - 8.2 7.0 12.4 7.2 7.2 2.0 3.4 3 1 0 3 3 3 0 Adhesion protein FadA RRM_1 PF00076.22 GAX28181.1 - 3.1e-18 65.3 0.0 5.4e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 GAX28181.1 - 7.5e-12 45.7 2.6 1.3e-11 45.0 2.6 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_occluded PF16842.5 GAX28181.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif Ribosomal_L13e PF01294.18 GAX28182.1 - 1.4e-53 181.4 2.1 2.4e-53 180.7 2.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L13e PH PF00169.29 GAX28184.1 - 2.8e-08 34.2 0.0 7.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 GAX28184.1 - 1.8e-06 28.3 0.3 3.9e-05 24.0 0.0 2.5 1 1 1 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 GAX28184.1 - 0.085 13.2 0.1 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain tRNA_bind PF01588.20 GAX28185.1 - 6e-24 84.0 0.0 1.1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain RRM_1 PF00076.22 GAX28186.1 - 2.7e-16 59.2 0.0 4.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX28186.1 - 3.9e-07 29.7 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LapA_dom PF06305.11 GAX28186.1 - 0.0039 17.0 0.1 0.0059 16.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain 2Fe-2S_thioredx PF01257.19 GAX28187.1 - 1.1e-05 25.4 0.5 1.5e-05 24.9 0.3 1.3 1 1 1 2 2 2 1 Thioredoxin-like [2Fe-2S] ferredoxin Sec2p PF06428.11 GAX28189.1 - 0.0059 16.6 0.4 0.0059 16.6 0.4 2.9 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF2935 PF11155.8 GAX28189.1 - 0.032 14.6 0.4 0.5 10.7 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Cep57_MT_bd PF06657.13 GAX28189.1 - 0.19 12.2 6.5 1.3 9.5 1.9 3.3 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DMPK_coil PF08826.10 GAX28189.1 - 0.41 10.8 6.0 2.4 8.3 5.9 2.4 1 1 0 1 1 1 0 DMPK coiled coil domain like IF2_N PF04760.15 GAX28189.1 - 1.3 8.9 4.0 1.1 9.1 0.3 2.7 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TPR_MLP1_2 PF07926.12 GAX28189.1 - 3.3 7.8 19.8 0.035 14.2 9.6 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 GAX28189.1 - 4.7 7.7 17.9 0.11 12.9 4.5 3.2 3 0 0 3 3 3 0 Syntaxin-like protein HMG_box PF00505.19 GAX28190.1 - 1.5e-16 60.6 1.3 4.1e-16 59.1 1.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX28190.1 - 1.1e-13 51.5 2.2 1.1e-13 51.5 2.2 1.9 2 0 0 2 2 2 1 HMG-box domain CBFD_NFYB_HMF PF00808.23 GAX28190.1 - 3.8e-10 39.9 0.2 1.5e-09 38.0 0.2 2.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX28190.1 - 9e-05 22.8 0.2 9e-05 22.8 0.2 2.4 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAX28190.1 - 0.3 11.3 2.5 0.46 10.7 0.2 2.3 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) NUP50 PF08911.11 GAX28191.1 - 1.4e-08 35.3 1.9 1.4e-08 35.3 1.9 4.2 2 1 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) eIF3_subunit PF08597.10 GAX28191.1 - 0.14 12.1 2.4 0.21 11.5 2.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PT PF04886.12 GAX28192.1 - 0.00035 20.0 19.0 0.00035 20.0 19.0 10.6 6 4 1 7 7 7 2 PT repeat CarbpepA_inh PF02977.15 GAX28194.1 - 0.034 13.9 0.6 0.034 13.9 0.6 2.3 2 1 0 2 2 2 0 Carboxypeptidase A inhibitor EB PF01683.18 GAX28194.1 - 0.38 11.1 8.6 4.3 7.7 8.6 2.1 1 1 0 1 1 1 0 EB module Gamma-thionin PF00304.20 GAX28194.1 - 2.2 8.6 8.5 0.92 9.8 5.7 1.9 1 1 0 1 1 1 0 Gamma-thionin family DX PF01666.17 GAX28194.1 - 5.8 7.4 8.5 1.4 9.4 1.8 2.3 1 1 1 2 2 2 0 DX module CPSase_L_D2 PF02786.17 GAX28196.1 - 7.6e-68 228.1 0.0 1.9e-67 226.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 GAX28196.1 - 1.2e-66 224.3 0.0 2.1e-66 223.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 GAX28196.1 - 1.1e-35 122.5 0.4 1.1e-34 119.2 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAX28196.1 - 1.7e-32 111.7 0.0 6.3e-32 109.9 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 GAX28196.1 - 5.2e-29 101.6 0.0 9.2e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 GAX28196.1 - 7.6e-18 64.1 5.4 8.3e-18 64.0 2.9 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAX28196.1 - 1.3e-13 50.5 0.5 7e-06 25.8 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAX28196.1 - 1e-10 41.5 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 GAX28196.1 - 7.6e-07 29.8 1.3 0.086 13.6 0.0 3.5 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp PF02222.22 GAX28196.1 - 9.8e-07 28.5 0.0 3.3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 GAX28196.1 - 1.2e-06 27.9 0.2 0.021 14.1 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 GAX28196.1 - 0.00055 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 GAX28196.1 - 0.0012 18.8 0.3 0.0034 17.3 0.3 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 GAX28196.1 - 0.0054 16.2 0.2 0.0099 15.3 0.2 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PTS_EIIA_1 PF00358.20 GAX28196.1 - 0.011 15.5 0.2 0.32 10.8 0.1 2.7 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ATP-grasp_4 PF13535.6 GAX28196.1 - 0.024 14.2 0.0 0.056 13.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain TTL PF03133.15 GAX28196.1 - 0.026 13.7 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family HK97-gp10_like PF04883.12 GAX28196.1 - 0.032 15.2 0.0 0.54 11.3 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component PYNP_C PF07831.13 GAX28196.1 - 0.098 12.3 0.2 0.68 9.6 0.0 2.4 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain AAA_5 PF07728.14 GAX28197.1 - 3e-69 231.4 0.0 4.2e-24 85.1 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX28197.1 - 8.9e-07 29.4 5.0 0.31 11.4 0.0 5.5 4 2 2 6 6 6 2 AAA ATPase domain AAA PF00004.29 GAX28197.1 - 7.5e-06 26.4 0.0 0.29 11.6 0.0 3.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 GAX28197.1 - 0.00034 19.9 0.0 0.00065 19.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain VWA_2 PF13519.6 GAX28197.1 - 0.0016 19.1 0.0 0.0039 17.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.21 GAX28197.1 - 0.0045 16.4 0.0 1.1 8.6 0.0 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAX28197.1 - 0.0048 16.8 0.0 6.3 6.7 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAX28197.1 - 0.022 14.5 0.0 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein VWA PF00092.28 GAX28197.1 - 0.027 14.7 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain RuvB_N PF05496.12 GAX28197.1 - 0.048 13.4 0.0 0.99 9.1 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAX28197.1 - 0.072 13.2 0.0 9.6 6.3 0.0 3.1 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 GAX28197.1 - 0.15 11.9 0.3 14 5.5 0.0 3.6 3 1 0 3 3 3 0 NACHT domain E1_dh PF00676.20 GAX28198.1 - 5.3e-51 173.4 0.0 9.2e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.20 GAX28198.1 - 1.4e-25 89.6 0.2 5.3e-25 87.7 0.1 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 GAX28198.1 - 3e-14 53.1 0.0 8.1e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 GAX28198.1 - 0.0024 17.7 0.2 0.0024 17.7 0.2 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 GAX28198.1 - 0.004 17.5 0.0 0.02 15.2 0.0 2.2 1 1 1 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II DXP_synthase_N PF13292.6 GAX28198.1 - 0.031 13.5 0.1 0.055 12.7 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase FAM91_C PF14648.6 GAX28198.1 - 0.073 11.9 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 FAM91 C-terminus PLU-1 PF08429.11 GAX28200.1 - 1.4e-40 139.5 52.8 1.1e-13 51.2 4.1 7.7 5 1 3 8 8 8 6 PLU-1-like protein PHD PF00628.29 GAX28200.1 - 5.1e-21 74.3 24.7 2.6e-10 40.0 5.4 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 GAX28200.1 - 0.038 13.6 16.6 0.3 10.7 3.1 2.5 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 GAX28200.1 - 0.13 12.4 11.8 0.37 10.9 5.0 2.8 2 0 0 2 2 2 0 PHD-finger PHD_3 PF13922.6 GAX28200.1 - 3.5 8.1 7.7 1.7 9.1 0.6 2.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx P4Ha_N PF08336.11 GAX28200.1 - 3.6 7.6 6.0 5.3 7.1 0.0 4.3 4 1 0 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region zf-CW PF07496.15 GAX28200.1 - 9.9 6.3 13.7 0.93 9.6 1.1 2.8 2 0 0 2 2 2 0 CW-type Zinc Finger TMEM43 PF07787.12 GAX28201.1 - 1.7e-68 230.7 0.4 2.3e-68 230.3 0.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 43 NAD_binding_4 PF07993.12 GAX28201.1 - 0.14 11.3 0.3 9.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DUF3185 PF11381.8 GAX28201.1 - 3.3 7.8 0.0 3.3 7.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) U3snoRNP10 PF12397.8 GAX28202.1 - 4.7e-11 43.1 0.6 3.5e-09 37.0 0.0 4.2 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 BP28CT PF08146.12 GAX28202.1 - 3.7e-09 36.6 0.1 6e-08 32.7 0.0 2.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain HEAT_2 PF13646.6 GAX28202.1 - 0.071 13.5 3.6 20 5.6 0.0 4.0 3 0 0 3 3 3 0 HEAT repeats Glutaredoxin PF00462.24 GAX28203.1 - 0.00013 22.1 0.0 0.00049 20.3 0.0 2.0 2 1 0 2 2 2 1 Glutaredoxin TLD PF07534.16 GAX28204.1 - 3.7e-20 72.6 0.0 8.7e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 GAX28204.1 - 8.7e-10 38.6 0.1 1.2e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rotamase PF00639.21 GAX28205.1 - 7.4e-22 78.1 0.0 1.5e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAX28205.1 - 1.2e-16 61.2 0.0 2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 GAX28205.1 - 1.8e-08 34.3 1.3 3.2e-08 33.5 1.3 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 GAX28205.1 - 0.00011 23.0 0.3 0.00025 21.8 0.0 1.9 3 0 0 3 3 3 1 PPIC-type PPIASE domain X8 PF07983.13 GAX28205.1 - 0.03 15.0 0.0 0.06 14.0 0.0 1.4 1 0 0 1 1 1 0 X8 domain UBA PF00627.31 GAX28206.1 - 4e-14 52.2 0.0 1.2e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.16 GAX28206.1 - 0.00013 21.6 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 GAX28206.1 - 0.016 15.0 0.1 0.32 10.8 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain UBA_3 PF09288.10 GAX28206.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain TraL PF07178.11 GAX28206.1 - 8 7.0 8.3 0.62 10.6 0.6 2.7 2 1 1 3 3 3 0 TraL protein LSM PF01423.22 GAX28207.1 - 2.6e-20 71.9 0.0 3.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAX28207.1 - 0.058 13.5 0.0 0.074 13.2 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 GAX28207.1 - 0.072 13.2 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Glyoxalase PF00903.25 GAX28208.1 - 0.0069 16.6 0.0 3.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Epimerase PF01370.21 GAX28209.1 - 3.5e-43 147.8 0.0 4.1e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX28209.1 - 1.1e-28 100.7 0.0 4.5e-27 95.3 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAX28209.1 - 9.5e-12 44.5 0.0 1.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAX28209.1 - 2.9e-05 24.0 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAX28209.1 - 0.00025 20.3 0.0 0.27 10.3 0.0 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.13 GAX28209.1 - 0.00078 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 GAX28209.1 - 0.0018 17.8 0.1 0.0025 17.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GAX28209.1 - 0.004 16.4 0.0 0.041 13.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 GAX28209.1 - 0.0066 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 GAX28209.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX28209.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 GAX28209.1 - 0.078 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Gamma_PGA_hydro PF05908.11 GAX28209.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase PPR_2 PF13041.6 GAX28210.1 - 1.7e-25 89.0 8.1 2.9e-06 27.4 0.1 8.5 7 2 1 8 8 8 5 PPR repeat family PPR_1 PF12854.7 GAX28210.1 - 8.1e-15 54.2 7.7 0.0092 15.7 0.0 8.9 9 1 0 9 9 9 5 PPR repeat PPR_3 PF13812.6 GAX28210.1 - 4.4e-14 52.3 5.3 0.0014 18.7 0.1 8.3 5 2 4 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.20 GAX28210.1 - 8.1e-11 41.4 11.4 0.25 11.7 0.0 9.8 10 1 0 10 10 10 3 PPR repeat PPR_long PF17177.4 GAX28210.1 - 1.3e-08 34.5 8.9 0.0097 15.3 0.4 5.0 1 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 GAX28210.1 - 7.1e-06 26.4 3.1 0.015 15.7 0.0 4.4 2 1 3 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) Nipped-B_C PF12830.7 GAX28210.1 - 0.0047 16.9 0.2 0.014 15.4 0.2 1.8 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus HD_assoc PF13286.6 GAX28210.1 - 0.089 13.3 1.1 2.1 9.0 0.0 3.3 2 1 1 3 3 3 0 Phosphohydrolase-associated domain KH_8 PF17903.1 GAX28211.1 - 3.8e-31 107.0 0.0 1.3e-30 105.4 0.0 1.9 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 GAX28211.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 KH domain Sec63 PF02889.16 GAX28212.1 - 1.6e-32 112.7 0.3 2.1e-32 112.3 0.3 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 GAX28212.1 - 7.2e-21 74.1 0.6 2.8e-20 72.2 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain Coprogen_oxidas PF01218.18 GAX28214.1 - 1.9e-96 322.3 0.0 2.5e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glyco_tran_28_C PF04101.16 GAX28215.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Myb_DNA-bind_5 PF13873.6 GAX28216.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Ferric_reduct PF01794.19 GAX28217.1 - 2e-13 50.6 10.6 2e-13 50.6 10.6 2.8 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAX28217.1 - 1.4e-05 25.3 0.0 3.5e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAX28218.1 - 5.6e-13 49.1 13.8 5.6e-13 49.1 13.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAX28218.1 - 0.0013 18.9 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DHHC PF01529.20 GAX28218.1 - 0.018 15.2 1.5 0.018 15.2 1.5 3.8 2 1 2 4 4 4 0 DHHC palmitoyltransferase Herpes_UL79 PF03049.14 GAX28218.1 - 0.093 12.4 0.6 0.15 11.7 0.6 1.3 1 0 0 1 1 1 0 UL79 family Cytochrom_B_C PF00032.17 GAX28218.1 - 0.16 12.3 6.9 0.1 12.9 3.8 2.4 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Dymeclin PF09742.9 GAX28219.1 - 2.3e-167 558.2 0.0 2.6e-167 558.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 GAX28219.1 - 4.7e-164 547.6 0.0 7.1e-139 464.4 0.0 2.1 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein PALP PF00291.25 GAX28220.1 - 3.7e-64 216.9 1.1 4.3e-64 216.8 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 GAX28220.1 - 0.013 15.5 0.3 0.034 14.1 0.3 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ALG3 PF05208.13 GAX28221.1 - 3.7e-125 418.1 16.9 4.6e-125 417.8 16.9 1.1 1 0 0 1 1 1 1 ALG3 protein Pkinase PF00069.25 GAX28222.1 - 6.3e-65 219.1 0.0 7.4e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX28222.1 - 2.3e-28 99.2 0.0 2.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAX28222.1 - 0.00036 20.6 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rhodanese PF00581.20 GAX28223.1 - 1.2e-07 32.2 0.0 1.7e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DEAD PF00270.29 GAX28224.1 - 1.8e-11 44.1 0.0 4.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2_2 PF12756.7 GAX28224.1 - 0.11 12.8 1.2 0.39 11.1 1.2 2.0 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) NMT1 PF09084.11 GAX28225.1 - 3.7e-42 144.7 0.0 2.9e-41 141.8 0.0 2.0 1 1 0 1 1 1 1 NMT1/THI5 like His_Phos_1 PF00300.22 GAX28226.1 - 1.4e-58 197.8 0.0 5e-24 85.1 0.0 4.4 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Patatin PF01734.22 GAX28227.1 - 2.3e-24 86.7 0.7 5.8e-24 85.4 0.2 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase CSRNP_N PF16019.5 GAX28229.1 - 4.7e-06 26.7 1.4 4.7e-06 26.7 1.4 4.8 2 2 1 3 3 3 1 Cysteine/serine-rich nuclear protein N-terminus CCDC106 PF15794.5 GAX28229.1 - 1 9.0 10.7 2.9 7.5 10.7 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 GAX28229.1 - 1.1 8.0 2.2 1.7 7.4 2.2 1.3 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 GAX28229.1 - 1.7 8.6 4.8 5.4 6.9 4.0 2.1 2 0 0 2 2 2 0 N-glycosylation protein Ank_2 PF12796.7 GAX28230.1 - 0.0015 19.1 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) TraG-D_C PF12696.7 GAX28230.1 - 0.076 13.0 0.8 0.25 11.3 0.8 1.8 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Ank_4 PF13637.6 GAX28230.1 - 0.15 12.7 0.0 3 8.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) UBA PF00627.31 GAX28230.1 - 1.2 9.1 3.5 1.8 8.5 0.0 2.6 3 0 0 3 3 3 0 UBA/TS-N domain Glutaredoxin PF00462.24 GAX28231.1 - 2.5e-18 66.0 0.0 3.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 GAX28231.1 - 0.00012 22.5 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 GAX28231.1 - 0.0028 17.9 0.0 0.004 17.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 GAX28231.1 - 0.012 15.6 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.6 GAX28231.1 - 0.023 15.1 0.1 0.039 14.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 GAX28231.1 - 0.047 14.1 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 GAX28231.1 - 0.69 9.7 2.8 7.6 6.3 0.4 2.2 1 1 0 2 2 2 0 DSBA-like thioredoxin domain PT PF04886.12 GAX28232.1 - 0.44 10.1 44.2 0.15 11.6 21.6 3.2 2 1 1 3 3 3 0 PT repeat LRR_8 PF13855.6 GAX28233.1 - 1.3e-27 95.3 53.7 2.7e-05 23.8 1.7 10.0 6 2 5 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 GAX28233.1 - 6.1e-21 74.2 57.4 7.8e-05 23.0 0.4 12.9 6 4 9 15 15 15 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX28233.1 - 1.9e-07 30.7 40.3 5.1 8.0 0.0 15.4 18 1 1 19 19 19 2 Leucine Rich Repeat LRR_6 PF13516.6 GAX28233.1 - 0.00033 20.5 36.5 6.5 7.1 0.1 14.1 16 0 0 16 16 16 2 Leucine Rich repeat LRRNT_2 PF08263.12 GAX28233.1 - 0.25 11.7 1.9 0.97 9.8 1.9 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain RB_B PF01857.20 GAX28234.1 - 6.2e-26 91.0 0.6 2.4e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain RB_A PF01858.17 GAX28234.1 - 9.7e-21 74.5 1.0 1.9e-20 73.5 0.5 1.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain dUTPase_2 PF08761.11 GAX28235.1 - 0.072 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 dUTPase ubiquitin PF00240.23 GAX28236.1 - 1.8e-162 527.4 20.4 2.9e-14 52.5 0.0 14.6 14 1 0 14 14 14 14 Ubiquitin family Rad60-SLD PF11976.8 GAX28236.1 - 8.7e-89 291.4 17.0 1.1e-09 38.0 0.0 14.4 14 0 0 14 14 14 13 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAX28236.1 - 1.5e-42 143.9 12.9 0.0027 18.1 0.0 14.3 10 2 3 13 13 13 10 Ubiquitin-like domain TBK1_ULD PF18396.1 GAX28236.1 - 3.4e-31 107.0 0.0 0.0059 16.5 0.0 12.2 12 1 1 13 13 13 7 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAX28236.1 - 2.9e-23 81.7 11.8 0.12 12.5 0.0 16.3 12 5 2 14 14 14 4 Ubiquitin-like domain UN_NPL4 PF11543.8 GAX28236.1 - 8.9e-17 61.4 0.0 4.9 7.7 0.0 11.2 10 2 2 12 12 11 3 Nuclear pore localisation protein NPL4 TUG-UBL1 PF11470.8 GAX28236.1 - 8e-16 58.0 0.0 0.21 11.9 0.0 9.3 10 0 0 10 10 9 2 TUG ubiquitin-like domain UBX PF00789.20 GAX28236.1 - 2.8e-11 43.5 0.0 13 6.0 0.0 9.9 9 1 1 10 10 10 0 UBX domain FERM_N PF09379.10 GAX28236.1 - 2.7e-08 33.6 0.1 16 5.5 0.0 7.4 8 0 0 8 8 8 0 FERM N-terminal domain RBD PF02196.15 GAX28236.1 - 3.7e-08 33.3 3.2 2.8 8.1 0.0 6.2 6 0 0 6 6 5 2 Raf-like Ras-binding domain YukD PF08817.10 GAX28236.1 - 1.1e-06 29.2 12.1 0.15 12.8 0.0 7.9 7 0 0 7 7 7 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.6 GAX28236.1 - 6.4e-06 26.3 1.2 25 5.0 0.0 8.1 10 0 0 10 10 10 0 Ubiquitin-2 like Rad60 SUMO-like GABP-alpha PF11620.8 GAX28236.1 - 0.0005 20.2 3.1 4.5 7.5 0.1 5.9 5 1 1 6 6 5 1 GA-binding protein alpha chain Raf1_HTH PF18579.1 GAX28236.1 - 0.0041 16.8 0.5 26 4.6 0.2 4.7 5 0 0 5 5 5 0 Rubisco accumulation factor 1 helix turn helix domain Inhibitor_I24 PF10465.9 GAX28236.1 - 0.015 15.3 0.1 57 3.7 0.0 4.4 3 2 0 3 3 3 0 PinA peptidase inhibitor Rootletin PF15035.6 GAX28236.1 - 0.035 14.1 2.3 0.087 12.8 2.3 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lac_bphage_repr PF06543.12 GAX28236.1 - 0.083 12.9 0.1 2.7 8.1 0.0 2.9 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor TmoB PF06234.12 GAX28236.1 - 4.8 7.3 9.7 37 4.5 0.0 6.0 7 0 0 7 7 7 0 Toluene-4-monooxygenase system protein B (TmoB) Pyrid_oxidase_2 PF13883.6 GAX28237.1 - 1.4e-18 67.4 0.0 3.6e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 GAX28237.1 - 1.9e-13 50.9 0.0 3.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 GAX28237.1 - 1.5e-08 34.7 0.0 6.7e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase bZIP_1 PF00170.21 GAX28238.1 - 0.00025 21.1 9.2 0.00025 21.1 9.2 2.1 3 0 0 3 3 3 1 bZIP transcription factor DUF3467 PF11950.8 GAX28239.1 - 0.0034 17.5 0.0 0.0037 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3467) bZIP_1 PF00170.21 GAX28240.1 - 2.8e-07 30.5 4.2 8.5e-07 29.0 4.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor Metal_resist PF13801.6 GAX28240.1 - 0.0017 18.6 1.7 0.0017 18.6 1.7 2.7 3 0 0 3 3 3 1 Heavy-metal resistance Phage_GPO PF05929.11 GAX28240.1 - 0.0099 15.5 3.6 0.01 15.5 1.9 1.8 1 1 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase bZIP_2 PF07716.15 GAX28240.1 - 0.034 14.2 8.6 0.034 14.2 8.6 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Peptidase_S41_N PF11918.8 GAX28240.1 - 0.041 14.1 2.2 0.13 12.5 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP DUF5356 PF17309.2 GAX28240.1 - 0.23 11.5 0.1 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5356) Alba PF01918.21 GAX28241.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Alba Cytidylate_kin2 PF13189.6 GAX28241.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family FAD_binding_7 PF03441.14 GAX28242.1 - 1.4e-59 201.0 1.2 2.2e-59 200.4 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAX28242.1 - 1.9e-33 115.8 0.7 8.7e-33 113.6 0.0 2.2 3 0 0 3 3 3 1 DNA photolyase Tox-REase-2 PF15646.6 GAX28243.1 - 0.014 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 HhH-GPD PF00730.25 GAX28246.1 - 1.6e-21 76.8 0.2 3.8e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAX28246.1 - 0.00082 19.1 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Methyltransf_16 PF10294.9 GAX28247.1 - 8e-11 42.0 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAX28247.1 - 9.8e-05 22.2 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX28248.1 - 3.3e-16 59.7 0.7 3.5e-15 56.3 0.7 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX28248.1 - 4.1e-07 30.6 0.2 1.8e-06 28.6 0.2 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28248.1 - 2.5e-05 24.1 0.0 6.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX28248.1 - 3.8e-05 24.2 0.1 0.00012 22.7 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX28248.1 - 0.0015 19.2 0.1 0.005 17.6 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX28248.1 - 0.003 17.4 0.0 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAX28248.1 - 0.0051 16.4 0.3 0.033 13.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain AAA PF00004.29 GAX28249.1 - 8.7e-46 155.6 0.0 5.2e-36 124.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX28249.1 - 1.9e-13 51.1 0.0 8e-06 26.3 0.0 3.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAX28249.1 - 3.6e-06 27.3 4.7 0.17 12.2 0.1 3.7 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.6 GAX28249.1 - 1.2e-05 25.8 0.0 0.02 15.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAX28249.1 - 5.7e-05 23.5 0.1 0.54 10.7 0.0 2.9 2 2 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 GAX28249.1 - 5.7e-05 22.9 0.0 0.029 14.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 GAX28249.1 - 0.00017 21.8 0.0 0.011 15.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAX28249.1 - 0.00038 20.6 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 GAX28249.1 - 0.00085 19.1 0.0 0.065 13.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 GAX28249.1 - 0.015 14.7 0.0 0.4 10.1 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein Sigma54_activat PF00158.26 GAX28249.1 - 0.02 14.6 0.0 4.2 7.0 0.0 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 GAX28249.1 - 0.02 14.9 0.1 0.79 9.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAX28249.1 - 0.024 14.9 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAX28249.1 - 0.027 14.4 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 GAX28249.1 - 0.034 14.2 0.0 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX28249.1 - 0.037 13.5 0.0 7 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 GAX28249.1 - 0.07 12.9 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 GAX28249.1 - 0.088 12.1 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 GAX28249.1 - 0.095 12.5 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 GAX28249.1 - 1.1 9.1 3.2 15 5.5 0.1 3.4 3 1 1 4 4 4 0 NACHT domain PT PF04886.12 GAX28251.1 - 4.6e-21 74.1 153.0 0.0014 18.1 13.9 8.6 1 1 6 7 7 7 6 PT repeat Cupin_8 PF13621.6 GAX28252.1 - 4.2e-09 36.5 0.2 1.5e-08 34.7 0.2 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX28252.1 - 2.4e-05 24.0 2.6 4.4e-05 23.1 2.6 1.5 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 GAX28252.1 - 0.018 14.8 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Cupin domain Capsid_NCLDV PF04451.12 GAX28252.1 - 0.043 13.6 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein JmjC PF02373.22 GAX28252.1 - 0.18 12.2 5.1 0.36 11.3 0.6 3.2 3 1 0 3 3 3 0 JmjC domain, hydroxylase C2 PF00168.30 GAX28254.1 - 5.5e-11 42.7 0.1 2.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 C2 domain DUF4497 PF14924.6 GAX28254.1 - 0.13 12.8 0.0 1.6 9.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) DCP1 PF06058.13 GAX28255.1 - 8.9e-27 93.4 0.1 1.3e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family WH1 PF00568.23 GAX28255.1 - 0.0023 17.8 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 WH1 domain mRNA_decap_C PF16741.5 GAX28255.1 - 0.0038 16.5 1.0 0.0067 15.7 1.0 1.4 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus SSP160 PF06933.11 GAX28255.1 - 6.6 4.8 11.8 9.6 4.3 11.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_12 PF13424.6 GAX28256.1 - 0.0015 18.7 0.6 0.0045 17.2 0.6 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat SET PF00856.28 GAX28256.1 - 0.0039 17.6 0.0 0.017 15.5 0.0 2.1 1 1 0 1 1 1 1 SET domain bZIP_1 PF00170.21 GAX28257.1 - 1.2e-05 25.2 7.2 1.2e-05 25.2 7.2 2.5 3 0 0 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.17 GAX28257.1 - 0.024 15.2 1.4 0.024 15.2 1.4 4.0 2 2 1 4 4 4 0 bZIP Maf transcription factor YqjK PF13997.6 GAX28257.1 - 0.11 12.8 4.4 2.1 8.6 1.4 2.9 2 0 0 2 2 2 0 YqjK-like protein Bap31_Bap29_C PF18035.1 GAX28257.1 - 0.12 12.4 3.1 0.29 11.1 3.1 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Plk4_PB2 PF18409.1 GAX28257.1 - 2.7 8.7 7.0 0.65 10.7 1.4 2.4 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 LAGLIDADG_WhiA PF14527.6 GAX28257.1 - 5.1 7.2 5.6 0.8 9.8 0.3 2.5 4 0 0 4 4 4 0 WhiA LAGLIDADG-like domain KAsynt_C_assoc PF16197.5 GAX28257.1 - 6.6 7.2 8.7 3.9 8.0 0.5 3.5 2 1 2 4 4 4 0 Ketoacyl-synthetase C-terminal extension DUF952 PF06108.12 GAX28261.1 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF952) EutQ PF06249.12 GAX28261.1 - 0.024 14.4 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Sushi_2 PF09014.10 GAX28263.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain TMEM61 PF15105.6 GAX28264.1 - 0.084 12.7 1.1 12 5.7 0.1 2.6 2 0 0 2 2 2 0 TMEM61 protein family Ndc1_Nup PF09531.10 GAX28265.1 - 0.02 13.6 0.5 0.02 13.6 0.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 GAX28265.1 - 0.1 11.8 16.1 0.15 11.2 16.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP2 PF01569.21 GAX28267.1 - 3.1e-10 40.0 0.1 5.5e-09 35.9 0.2 2.6 2 1 0 2 2 2 1 PAP2 superfamily Isochorismatase PF00857.20 GAX28268.1 - 6.3e-26 91.6 0.3 8e-26 91.3 0.3 1.1 1 0 0 1 1 1 1 Isochorismatase family IGPD PF00475.18 GAX28269.1 - 3.4e-64 215.5 0.0 5.6e-31 107.8 0.0 2.5 2 1 1 3 3 3 2 Imidazoleglycerol-phosphate dehydratase SNAP PF14938.6 GAX28269.1 - 0.0095 15.4 0.5 0.015 14.8 0.5 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF1990 PF09348.10 GAX28270.1 - 2.4e-16 60.1 2.9 1.4e-14 54.4 2.9 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1990) DUF2973 PF11189.8 GAX28271.1 - 0.13 12.4 0.1 0.45 10.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Amino_oxidase PF01593.24 GAX28272.1 - 5.4e-78 263.3 0.0 1.5e-77 261.8 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase zf-HC5HC2H PF13771.6 GAX28272.1 - 2.5e-15 56.5 35.7 4.2e-11 43.0 7.3 4.4 3 1 1 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAX28272.1 - 2.8e-15 56.4 27.5 6.3e-10 39.2 7.1 2.8 2 0 0 2 2 2 2 PHD-zinc-finger like domain NAD_binding_8 PF13450.6 GAX28272.1 - 1e-12 48.1 0.1 3.1e-12 46.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX28272.1 - 5.6e-05 22.9 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX28272.1 - 8.8e-05 22.5 1.2 0.00051 20.1 0.2 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAX28272.1 - 0.0009 18.6 0.0 0.0038 16.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAX28272.1 - 0.0058 17.2 1.1 0.016 15.8 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX28272.1 - 0.011 14.8 0.5 0.1 11.6 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAX28272.1 - 0.098 11.7 1.4 0.15 11.1 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain PFL-like PF02901.15 GAX28273.1 - 4.6e-169 564.1 0.0 7.2e-169 563.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 GAX28273.1 - 4.8e-37 126.7 0.0 4.1e-36 123.7 0.0 2.7 3 0 0 3 3 3 1 Glycine radical Radical_SAM PF04055.21 GAX28273.1 - 2.7e-16 60.4 0.0 5.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAX28273.1 - 2.9e-11 43.8 0.2 6.2e-11 42.7 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3029 PF11230.8 GAX28273.1 - 0.00026 19.5 0.1 0.00057 18.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3029) Fer4_14 PF13394.6 GAX28273.1 - 0.0046 17.1 0.1 0.014 15.5 0.1 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain PRA1 PF03208.19 GAX28274.1 - 1.2e-18 67.1 3.6 1.5e-18 66.8 3.6 1.1 1 0 0 1 1 1 1 PRA1 family protein 2TM PF13239.6 GAX28274.1 - 1.2 9.5 9.2 0.87 9.9 1.8 2.4 2 0 0 2 2 2 0 2TM domain Ten1_2 PF15490.6 GAX28275.1 - 3.4e-08 33.2 0.2 1.1e-07 31.6 0.1 1.8 2 0 0 2 2 2 1 Telomere-capping, CST complex subunit ILVD_EDD PF00920.21 GAX28276.1 - 2.3e-204 679.8 0.0 2.7e-204 679.6 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family PEP-utilizers PF00391.23 GAX28276.1 - 0.012 15.4 0.9 0.031 14.0 0.2 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain FeoA PF04023.14 GAX28276.1 - 0.012 15.9 0.0 11 6.4 0.0 3.2 3 0 0 3 3 3 0 FeoA domain Rad51 PF08423.11 GAX28277.1 - 1.7e-118 394.5 0.9 2.3e-118 394.1 0.2 1.5 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 GAX28277.1 - 7e-13 48.6 0.2 1e-12 48.1 0.2 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 GAX28277.1 - 8.8e-10 38.5 0.1 1.4e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAX28277.1 - 3.6e-07 29.8 0.9 1.2e-06 28.0 0.9 1.9 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 GAX28277.1 - 5.9e-05 23.6 0.1 0.0002 21.9 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 GAX28277.1 - 0.00071 19.4 0.1 0.016 14.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX28277.1 - 0.0047 17.2 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain HHH_2 PF12826.7 GAX28277.1 - 0.014 15.5 0.1 0.072 13.2 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DnaB_C PF03796.15 GAX28277.1 - 0.027 13.8 0.2 0.51 9.6 0.1 2.4 1 1 0 2 2 2 0 DnaB-like helicase C terminal domain LPD22 PF18834.1 GAX28277.1 - 0.26 11.5 3.2 0.61 10.3 0.1 2.9 4 0 0 4 4 4 0 Large polyvalent protein associated domain 22 AAA_28 PF13521.6 GAX28277.1 - 0.34 11.1 3.7 1.3 9.3 0.6 3.0 2 2 1 3 3 3 0 AAA domain Na_H_Exchanger PF00999.21 GAX28278.1 - 4.9e-39 134.2 27.6 6.9e-39 133.7 27.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 GAX28279.1 - 1e-39 136.4 26.1 1.2e-39 136.2 26.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.25 GAX28280.1 - 7.5e-34 117.3 0.0 1.5e-33 116.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX28280.1 - 8e-34 117.1 0.0 1.4e-33 116.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX28280.1 - 0.00017 20.5 0.0 0.00034 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAX28280.1 - 0.0041 16.5 0.1 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAX28280.1 - 0.02 14.9 0.1 0.049 13.6 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glu_cyclase_2 PF05096.12 GAX28281.1 - 6.7e-65 219.0 0.2 8.2e-65 218.7 0.2 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase PQQ_2 PF13360.6 GAX28281.1 - 0.024 14.2 0.1 1.4 8.5 0.1 2.7 1 1 2 3 3 3 0 PQQ-like domain PepSY PF03413.19 GAX28281.1 - 0.028 15.0 0.0 3.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF1082 PF06449.11 GAX28281.1 - 0.13 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) NIR_SIR PF01077.22 GAX28282.1 - 4.1e-52 175.9 0.1 1.5e-37 128.6 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 GAX28282.1 - 6.8e-40 134.8 0.2 2e-20 72.4 0.0 2.7 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain UQ_con PF00179.26 GAX28283.1 - 5.6e-46 155.7 0.0 6.3e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAX28283.1 - 0.023 14.4 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 GAX28283.1 - 0.083 13.2 0.2 0.1 12.9 0.2 1.5 1 1 0 1 1 1 0 RWD domain AAA_2 PF07724.14 GAX28284.1 - 4.1e-52 176.8 0.0 8.3e-49 166.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAX28284.1 - 5.7e-33 113.0 1.6 5.7e-33 113.0 1.6 3.1 2 1 1 3 3 3 1 AAA lid domain ClpB_D2-small PF10431.9 GAX28284.1 - 1e-22 79.9 0.6 4.4e-22 77.9 0.2 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GAX28284.1 - 6.1e-21 75.2 0.1 1.4e-11 45.0 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX28284.1 - 8.5e-16 58.2 0.9 2e-09 37.6 0.0 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX28284.1 - 6.6e-12 46.1 9.4 3e-05 24.5 0.0 5.2 4 1 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 GAX28284.1 - 1.5e-10 41.0 0.3 0.00015 21.5 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 GAX28284.1 - 9.1e-10 38.9 2.2 0.0044 17.3 0.0 4.8 3 1 1 4 4 4 2 AAA domain TniB PF05621.11 GAX28284.1 - 7.6e-08 32.0 0.0 0.00011 21.7 0.1 4.0 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 GAX28284.1 - 4.8e-07 29.5 0.0 0.017 14.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAX28284.1 - 7.8e-07 29.0 0.0 0.058 13.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAX28284.1 - 1e-06 28.3 1.5 0.022 14.1 0.1 3.8 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 GAX28284.1 - 9.7e-06 26.2 11.0 0.72 10.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 GAX28284.1 - 1.7e-05 24.0 1.0 0.0043 16.2 0.1 3.2 3 1 0 3 3 3 1 Type II/IV secretion system protein RuvB_N PF05496.12 GAX28284.1 - 4.5e-05 23.2 0.8 0.14 11.9 0.0 3.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 GAX28284.1 - 7.1e-05 22.8 0.0 0.066 13.1 0.1 3.8 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAX28284.1 - 0.00025 21.3 1.9 0.26 11.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAX28284.1 - 0.00026 21.5 0.8 1.5 9.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain DivIC PF04977.15 GAX28284.1 - 0.00035 20.3 7.2 0.0011 18.7 7.2 2.0 1 0 0 1 1 1 1 Septum formation initiator AAA_19 PF13245.6 GAX28284.1 - 0.00043 20.7 0.4 0.67 10.3 0.1 3.8 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 GAX28284.1 - 0.00046 20.2 1.2 0.82 9.7 0.0 3.6 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 GAX28284.1 - 0.00055 19.8 0.0 0.039 13.7 0.0 3.5 3 1 0 3 3 3 1 DNA polymerase III, delta subunit NACHT PF05729.12 GAX28284.1 - 0.00056 19.9 0.4 0.043 13.7 0.0 3.3 4 0 0 4 4 3 1 NACHT domain TIP49 PF06068.13 GAX28284.1 - 0.00082 18.7 1.6 0.41 9.8 0.0 2.8 2 1 1 3 3 3 2 TIP49 P-loop domain PhoH PF02562.16 GAX28284.1 - 0.00093 18.7 0.0 0.048 13.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_6 PF12774.7 GAX28284.1 - 0.0017 17.4 0.1 0.083 11.8 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 GAX28284.1 - 0.0019 18.6 0.0 2.8 8.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 GAX28284.1 - 0.0034 17.1 0.0 0.7 9.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 GAX28284.1 - 0.0039 17.2 2.3 1.3 9.0 0.0 3.2 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 GAX28284.1 - 0.012 14.8 0.1 0.76 8.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) SRP54 PF00448.22 GAX28284.1 - 0.017 14.8 0.4 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 GAX28284.1 - 0.017 14.9 0.0 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 GAX28284.1 - 0.018 15.3 0.0 7.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 GAX28284.1 - 0.044 13.9 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Torsin ABC_tran PF00005.27 GAX28284.1 - 0.051 14.1 4.8 4.7 7.7 0.1 3.3 3 1 0 3 3 2 0 ABC transporter Parvo_NS1 PF01057.17 GAX28284.1 - 0.065 12.3 0.0 0.44 9.6 0.0 2.3 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 GAX28284.1 - 0.093 12.9 2.2 11 6.1 0.0 3.5 4 0 0 4 4 2 0 AAA domain Snapin_Pallidin PF14712.6 GAX28284.1 - 0.89 10.0 12.0 0.23 11.9 6.7 2.9 2 1 0 2 2 1 0 Snapin/Pallidin UPF0242 PF06785.11 GAX28284.1 - 1.8 8.6 15.3 2.8 8.0 13.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF87 PF01935.17 GAX28284.1 - 4.6 7.3 7.2 5.6 7.0 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain DnaJ PF00226.31 GAX28285.1 - 1e-22 80.0 0.5 1.7e-22 79.3 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain ShK PF01549.24 GAX28285.1 - 8.4e-09 35.8 4.6 1.4e-08 35.1 4.6 1.4 1 0 0 1 1 1 1 ShK domain-like Rab3-GTPase_cat PF13890.6 GAX28285.1 - 0.024 14.3 0.9 0.043 13.4 0.9 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit CSD PF00313.22 GAX28286.1 - 1.1e-18 66.8 0.7 1.4e-18 66.5 0.7 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 GAX28286.1 - 0.0005 19.7 0.3 0.00095 18.8 0.3 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain ABC_tran PF00005.27 GAX28287.1 - 4.6e-46 156.7 0.2 8.5e-22 78.1 0.0 4.1 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 GAX28287.1 - 1e-13 51.2 1.8 4.3e-05 23.1 0.0 4.4 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX28287.1 - 2.9e-13 50.3 0.0 0.006 16.4 0.0 4.4 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAX28287.1 - 1.1e-05 25.5 0.4 0.13 12.4 0.0 3.7 4 0 0 4 4 4 2 50S ribosome-binding GTPase 4HB PF17947.1 GAX28287.1 - 8.1e-05 22.6 1.1 0.00029 20.9 0.1 2.4 2 0 0 2 2 2 1 Four helical bundle domain HEAT_2 PF13646.6 GAX28287.1 - 8.6e-05 22.9 1.6 0.00044 20.6 0.0 2.9 3 1 0 3 3 2 1 HEAT repeats AAA_23 PF13476.6 GAX28287.1 - 0.00015 22.4 10.5 0.64 10.5 0.9 4.1 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 GAX28287.1 - 0.00019 21.7 0.0 0.35 11.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAX28287.1 - 0.00026 20.7 0.1 0.13 12.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAX28287.1 - 0.00026 21.2 0.0 0.22 11.8 0.0 4.2 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 GAX28287.1 - 0.00029 21.1 0.0 0.034 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAX28287.1 - 0.0003 20.7 0.1 0.016 15.1 0.0 2.7 2 1 0 2 2 2 1 RsgA GTPase HEAT_EZ PF13513.6 GAX28287.1 - 0.00089 19.7 5.6 0.011 16.3 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat CLP1_P PF16575.5 GAX28287.1 - 0.00098 19.0 0.0 0.093 12.5 0.0 2.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 GAX28287.1 - 0.0011 18.7 0.1 0.55 10.0 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 GAX28287.1 - 0.0012 19.3 0.0 0.45 10.9 0.0 3.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 GAX28287.1 - 0.0032 17.6 3.4 0.25 11.4 0.0 4.6 5 0 0 5 5 5 1 Helicase HerA, central domain DR2241 PF18069.1 GAX28287.1 - 0.0064 16.3 0.1 2.2 8.2 0.0 3.1 3 0 0 3 3 2 1 DR2241 stabilising domain Roc PF08477.13 GAX28287.1 - 0.011 15.9 0.0 5.6 7.2 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 GAX28287.1 - 0.011 15.4 10.8 0.62 9.7 0.0 3.9 4 1 0 4 4 3 0 AAA ATPase domain RNA_helicase PF00910.22 GAX28287.1 - 0.012 15.9 0.0 6 7.3 0.0 3.0 3 0 0 3 3 2 0 RNA helicase G-alpha PF00503.20 GAX28287.1 - 0.014 14.6 0.0 1.3 8.1 0.0 2.7 2 0 0 2 2 2 0 G-protein alpha subunit Vac14_Fab1_bd PF12755.7 GAX28287.1 - 0.042 14.4 0.0 1.2 9.8 0.0 3.0 3 1 1 4 4 3 0 Vacuolar 14 Fab1-binding region AAA_14 PF13173.6 GAX28287.1 - 0.042 13.9 0.0 1.2 9.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain HEAT PF02985.22 GAX28287.1 - 0.067 13.5 1.9 2.6 8.5 0.0 4.6 6 0 0 6 6 4 0 HEAT repeat NACHT PF05729.12 GAX28287.1 - 0.071 13.0 0.0 6.5 6.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 GAX28287.1 - 0.088 13.2 0.1 2.3 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ATP-synt_ab PF00006.25 GAX28287.1 - 0.12 12.0 0.1 0.77 9.4 0.0 2.2 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 GAX28287.1 - 0.63 9.6 3.0 8.3 5.9 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.23 GAX28287.1 - 0.63 10.1 3.1 0.82 9.7 0.0 2.8 3 0 0 3 3 2 0 Dynamin family AMPK1_CBM PF16561.5 GAX28288.1 - 5.7e-34 116.2 0.3 1e-33 115.4 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 GAX28288.1 - 3.5e-25 88.0 5.0 5.5e-25 87.4 5.0 1.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 GAX28288.1 - 0.12 12.7 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) BTAD PF03704.17 GAX28289.1 - 0.0065 16.9 0.2 0.0095 16.4 0.2 1.4 1 0 0 1 1 1 1 Bacterial transcriptional activator domain FANCI_S1-cap PF14674.6 GAX28289.1 - 3.1 8.0 5.3 2.6 8.2 1.2 2.5 2 1 1 3 3 3 0 FANCI solenoid 1 cap PCI PF01399.27 GAX28291.1 - 9.8e-09 35.7 4.4 2.6e-08 34.3 1.2 3.0 2 1 0 2 2 2 1 PCI domain HECT PF00632.25 GAX28293.1 - 8.1e-89 298.1 0.0 1.4e-88 297.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 GAX28293.1 - 6.9e-44 150.7 0.2 1e-26 94.2 0.1 2.9 2 0 0 2 2 2 2 Domain of Unknown Function (DUF908) DUF913 PF06025.12 GAX28293.1 - 5.4e-40 137.5 17.3 1.7e-32 112.8 0.5 4.4 3 1 1 4 4 4 2 Domain of Unknown Function (DUF913) UBM PF14377.6 GAX28293.1 - 1.5e-13 49.7 7.8 8.3e-07 28.3 0.2 4.6 3 1 1 4 4 4 3 Ubiquitin binding region UBA PF00627.31 GAX28293.1 - 3.2e-05 23.7 0.2 9.4e-05 22.2 0.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Peptidase_C42 PF05533.12 GAX28293.1 - 0.049 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 Arm PF00514.23 GAX28293.1 - 0.33 11.1 4.5 22 5.2 0.0 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat 5TM-5TMR_LYT PF07694.12 GAX28294.1 - 0.053 13.0 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT TMEM43 PF07787.12 GAX28294.1 - 0.063 12.6 0.1 0.096 12.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 PDR_CDR PF06422.12 GAX28294.1 - 0.11 12.4 1.2 11 6.1 0.3 2.8 2 1 1 3 3 3 0 CDR ABC transporter DUF2304 PF10066.9 GAX28294.1 - 0.69 10.2 4.1 2.2 8.5 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2304) Sod_Fe_C PF02777.18 GAX28295.1 - 1.6e-37 127.8 0.0 3.2e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAX28295.1 - 4.9e-28 97.4 0.5 1.2e-27 96.2 0.5 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FA_hydroxylase PF04116.13 GAX28296.1 - 4.2e-07 30.4 9.4 4.2e-07 30.4 9.4 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PP2C PF00481.21 GAX28298.1 - 2.5e-27 96.2 0.0 4.2e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 GAX28299.1 - 3.3e-16 59.7 0.0 1e-15 58.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAX28299.1 - 0.0048 16.6 0.4 0.012 15.2 0.4 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Rtf2 PF04641.12 GAX28300.1 - 3.1e-26 92.3 0.2 1.4e-25 90.2 0.2 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger PhoD PF09423.10 GAX28301.1 - 3.6e-17 62.4 0.3 3.6e-16 59.1 0.3 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase UvrC_HhH_N PF08459.11 GAX28303.1 - 5.4e-42 143.3 0.0 1.1e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal UvrB PF12344.8 GAX28303.1 - 1.1e-11 44.3 0.2 2.7e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 GAX28303.1 - 1.9e-11 44.3 0.0 4.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28303.1 - 2.7e-08 34.0 0.0 1e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GIY-YIG PF01541.24 GAX28303.1 - 3.3e-06 27.3 0.0 1.1e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA_30 PF13604.6 GAX28303.1 - 0.0012 18.6 0.0 0.0069 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 GAX28303.1 - 0.0031 17.3 0.0 0.052 13.3 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GAX28303.1 - 0.0053 17.1 0.1 2 8.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAX28303.1 - 0.0083 16.5 0.1 0.058 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF496 PF04363.12 GAX28303.1 - 0.019 15.0 1.5 0.93 9.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF496) AAA_22 PF13401.6 GAX28303.1 - 0.024 14.9 0.0 0.075 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAX28303.1 - 0.033 13.7 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Mal_decarbox_Al PF16957.5 GAX28303.1 - 0.1 10.9 0.0 4.3 5.5 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter Pox_F17 PF04767.12 GAX28303.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein UvrB_inter PF17757.1 GAX28303.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 UvrB interaction domain Fumble PF03630.14 GAX28303.1 - 0.19 10.9 0.0 14 4.7 0.0 2.2 2 0 0 2 2 2 0 Fumble DUF4306 PF14154.6 GAX28306.1 - 0.2 11.8 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Pkinase PF00069.25 GAX28307.1 - 2.4e-56 191.0 0.0 5.5e-56 189.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX28307.1 - 3.2e-43 145.7 0.5 6.1e-17 61.5 0.0 5.2 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX28307.1 - 6.2e-25 88.0 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX28307.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAX28307.1 - 0.099 12.5 0.0 2.7 7.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cupin_2 PF07883.11 GAX28307.1 - 0.11 12.2 0.2 5.5 6.8 0.0 3.4 3 0 0 3 3 3 0 Cupin domain TPM_phosphatase PF04536.14 GAX28309.1 - 1.3e-16 60.9 0.0 2.6e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 TPM domain MOLO1 PF17175.4 GAX28309.1 - 5.4e-16 58.8 0.0 2.8e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Modulator of levamisole receptor-1 zf-RING_2 PF13639.6 GAX28309.1 - 1.9e-08 34.5 4.5 1.9e-08 34.5 4.5 2.2 3 0 0 3 3 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAX28309.1 - 8.8e-07 28.7 1.7 0.00015 21.5 0.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAX28309.1 - 9e-06 25.6 0.8 9e-06 25.6 0.8 2.8 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAX28309.1 - 9e-05 22.3 1.6 9e-05 22.3 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX28309.1 - 9.4e-05 22.2 2.5 9.4e-05 22.2 2.5 2.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.14 GAX28309.1 - 0.00044 19.0 0.6 0.00071 18.4 0.6 1.3 1 0 0 1 1 1 1 Pellino FixQ PF05545.11 GAX28309.1 - 0.001 19.0 0.1 0.0026 17.7 0.1 1.6 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ zf-rbx1 PF12678.7 GAX28309.1 - 0.0011 19.2 3.4 0.0011 19.2 3.4 2.6 3 0 0 3 3 3 1 RING-H2 zinc finger domain HemX PF04375.14 GAX28309.1 - 0.0023 17.3 0.1 0.0036 16.7 0.1 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase zf-ANAPC11 PF12861.7 GAX28309.1 - 0.003 17.6 3.0 0.0077 16.3 1.5 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAX28309.1 - 0.0048 16.8 1.3 0.0048 16.8 1.3 2.7 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAX28309.1 - 0.017 14.9 9.3 0.025 14.4 3.8 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SARAF PF06682.12 GAX28309.1 - 0.042 13.5 0.6 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis zf-Di19 PF05605.12 GAX28309.1 - 0.053 13.8 0.6 3.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.5 GAX28309.1 - 0.095 12.3 0.3 0.29 10.8 0.3 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4381 PF14316.6 GAX28309.1 - 0.14 12.4 2.1 0.15 12.3 0.0 2.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4381) zf-C3HC4_4 PF15227.6 GAX28309.1 - 0.18 12.0 2.2 7.2 6.9 0.2 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 GAX28309.1 - 0.2 11.5 0.9 1 9.3 0.8 2.3 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 GAX28309.1 - 0.74 10.0 6.1 1 9.6 2.3 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 GAX28309.1 - 1.2 9.0 7.1 2.4 8.0 0.4 3.8 3 1 0 3 3 3 0 RING-like zinc finger FYVE_2 PF02318.16 GAX28309.1 - 1.8 8.8 4.7 0.39 10.9 0.6 2.0 2 1 0 2 2 2 0 FYVE-type zinc finger 2OG-FeII_Oxy_2 PF13532.6 GAX28311.1 - 1.9e-05 25.0 0.0 2.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PPR_2 PF13041.6 GAX28314.1 - 8.3e-39 131.6 7.2 1.2e-14 54.2 0.4 7.9 6 2 2 8 8 8 3 PPR repeat family PPR_3 PF13812.6 GAX28314.1 - 7.9e-28 96.3 11.2 5.7e-07 29.5 0.1 7.2 6 1 1 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 GAX28314.1 - 1.3e-23 81.5 8.4 1.7e-05 24.7 0.0 9.6 9 1 0 9 9 9 4 PPR repeat PPR_1 PF12854.7 GAX28314.1 - 6.3e-11 41.8 1.4 0.0012 18.5 0.0 6.6 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 GAX28314.1 - 1.3e-09 37.8 7.2 1.5e-05 24.5 0.2 3.7 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PDZ PF00595.24 GAX28314.1 - 5.7e-07 29.8 0.0 0.0037 17.6 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 GAX28314.1 - 1.2e-06 28.8 0.0 0.00094 19.5 0.0 2.6 1 1 1 2 2 2 2 PDZ domain PDZ_6 PF17820.1 GAX28314.1 - 0.0027 17.5 0.3 0.62 10.0 0.0 3.3 3 0 0 3 3 3 1 PDZ domain MNE1 PF13762.6 GAX28314.1 - 0.043 13.8 4.6 0.049 13.6 1.9 2.5 2 1 0 2 2 2 0 Mitochondrial splicing apparatus component Mic1 PF07035.12 GAX28314.1 - 0.058 13.1 0.1 17 5.1 0.0 3.0 1 1 1 2 2 2 0 Colon cancer-associated protein Mic1-like Prp18 PF02840.15 GAX28314.1 - 0.22 11.6 0.9 0.54 10.3 0.1 2.1 2 0 0 2 2 2 0 Prp18 domain Rad60-SLD PF11976.8 GAX28315.1 - 5.1e-15 55.1 1.4 5.8e-15 54.9 1.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAX28315.1 - 1.7e-09 37.3 0.4 1.9e-09 37.2 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX28316.1 - 1.5e-16 60.0 0.4 1.7e-16 59.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAX28316.1 - 8e-08 31.9 0.3 8.8e-08 31.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Cation_efflux PF01545.21 GAX28319.1 - 6.2e-14 52.2 0.0 1.1e-13 51.4 0.0 1.3 1 1 0 1 1 1 1 Cation efflux family ABATE PF07336.11 GAX28319.1 - 0.091 13.4 1.3 3.9 8.1 0.0 2.8 3 0 0 3 3 3 0 Putative stress-induced transcription regulator HMG_box PF00505.19 GAX28320.1 - 1.4e-55 185.5 10.4 8.6e-20 70.9 1.9 3.2 3 0 0 3 3 3 3 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX28320.1 - 4.8e-37 126.4 10.5 2.3e-15 56.9 0.0 3.4 3 0 0 3 3 3 3 HMG-box domain CHDNT PF08073.12 GAX28320.1 - 3.8e-08 33.2 0.2 0.015 15.2 0.0 3.3 3 0 0 3 3 3 3 CHDNT (NUC034) domain HMG_box_5 PF14887.6 GAX28320.1 - 8.3e-08 32.1 0.2 0.29 11.2 0.0 3.4 3 0 0 3 3 3 3 HMG (high mobility group) box 5 Ccdc124 PF06244.12 GAX28320.1 - 6.7e-06 26.7 0.8 0.069 13.7 0.1 3.4 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 124 /Oxs1 HTH_IclR PF09339.10 GAX28320.1 - 0.21 11.4 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Hid1 PF12722.7 GAX28321.1 - 8.7 4.3 9.7 9.4 4.2 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_L18A PF01775.17 GAX28322.1 - 3.4e-49 165.9 0.3 4.4e-49 165.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Inhibitor_I29 PF08246.12 GAX28322.1 - 0.028 14.8 0.7 0.087 13.3 0.7 1.9 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) tRNA_U5-meth_tr PF05958.11 GAX28324.1 - 5.4e-24 84.8 0.2 3.6e-23 82.1 0.1 2.1 1 1 1 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAX28324.1 - 1.3e-05 25.0 0.1 2.7e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX28324.1 - 1.9e-05 25.3 0.0 4.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAX28324.1 - 5.2e-05 22.8 0.0 9.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAX28324.1 - 0.00021 20.8 1.4 0.00027 20.4 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 GAX28324.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 GAX28324.1 - 0.0021 18.7 0.0 0.0044 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAX28324.1 - 0.0054 16.4 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TRAM PF01938.20 GAX28324.1 - 0.0076 16.2 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 TRAM domain RsmJ PF04378.13 GAX28324.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ TRM PF02005.16 GAX28324.1 - 0.058 12.5 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_4 PF02390.17 GAX28324.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GrpB PF04229.14 GAX28324.1 - 0.092 12.9 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 GrpB protein DUF4952 PF16310.5 GAX28324.1 - 0.097 12.9 0.0 10 6.5 0.0 2.9 3 0 0 3 3 3 0 Domian of unknown function (DUF4952) Methyltransf_32 PF13679.6 GAX28324.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain TPMT PF05724.11 GAX28324.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 GAX28324.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Spc42p PF11544.8 GAX28325.1 - 0.18 11.8 1.6 2.2 8.3 0.2 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p AAA_12 PF13087.6 GAX28326.1 - 2.7e-20 72.9 0.0 3.7e-19 69.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX28326.1 - 1e-12 48.4 12.7 9e-07 28.9 0.4 3.5 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 GAX28326.1 - 1.4e-07 31.5 0.2 5.4e-06 26.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 GAX28326.1 - 2.3e-05 24.8 0.1 0.0012 19.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain MTES_1575 PF18741.1 GAX28326.1 - 0.0033 17.6 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 REase_MTES_1575 DUF2075 PF09848.9 GAX28326.1 - 0.034 13.4 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 GAX28326.1 - 0.04 13.9 0.3 0.22 11.5 0.0 2.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAX28326.1 - 0.042 13.4 0.6 0.14 11.7 0.6 2.1 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 GAX28326.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 GAX28326.1 - 0.086 12.0 0.1 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 GAX28326.1 - 0.17 12.1 0.2 0.79 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain PspB PF06667.12 GAX28326.1 - 0.18 11.9 0.8 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 Phage shock protein B CRAL_TRIO PF00650.20 GAX28327.1 - 6.4e-26 91.0 0.1 1.1e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAX28327.1 - 0.00026 21.1 0.1 0.00044 20.4 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CppA_C PF14507.6 GAX28327.1 - 0.026 15.3 0.1 0.067 13.9 0.1 1.7 1 0 0 1 1 1 0 CppA C-terminal SNF2_N PF00176.23 GAX28328.1 - 9.8e-69 231.7 0.0 1.6e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAX28328.1 - 3.4e-33 114.1 2.2 4.9e-28 97.4 0.0 2.8 1 1 1 2 2 2 2 SLIDE Helicase_C PF00271.31 GAX28328.1 - 2.7e-19 69.5 0.0 8.3e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28328.1 - 2.9e-10 40.4 0.0 8.8e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX28328.1 - 9.4e-05 22.3 0.0 0.00027 20.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HAND PF09110.11 GAX28328.1 - 0.0004 21.1 1.2 0.0004 21.1 1.2 2.6 3 0 0 3 3 1 1 HAND SWI2_SNF2 PF18766.1 GAX28328.1 - 0.0025 17.5 0.0 0.0066 16.1 0.0 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase MTCP1 PF08991.10 GAX28328.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type HDA2-3 PF11496.8 GAX28328.1 - 0.018 14.2 0.0 0.046 12.9 0.0 1.8 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 GAX28328.1 - 0.047 13.3 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 DBINO PF13892.6 GAX28328.1 - 0.062 13.7 0.1 0.062 13.7 0.1 3.4 4 0 0 4 4 3 0 DNA-binding domain DNA_repr_REX1B PF14966.6 GAX28328.1 - 0.095 13.4 0.1 2.8 8.6 0.0 2.9 2 0 0 2 2 2 0 DNA repair REX1-B AAA_14 PF13173.6 GAX28328.1 - 0.1 12.6 0.0 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAX28328.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Silic_transp PF03842.13 GAX28329.1 - 6.1e-162 539.5 23.2 7.7e-162 539.2 23.2 1.0 1 0 0 1 1 1 1 Silicon transporter ChpA-C PF03777.13 GAX28329.1 - 0.12 12.3 0.5 0.22 11.4 0.5 1.4 1 0 0 1 1 1 0 ChpA-C TMEMspv1-c74-12 PF11044.8 GAX28329.1 - 2.4 8.2 5.6 12 6.0 5.6 2.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF3847 PF12958.7 GAX28330.1 - 0.01 15.9 0.3 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Lsr2 PF11774.8 GAX28330.1 - 0.091 12.9 0.1 0.43 10.7 0.0 1.9 1 1 1 2 2 2 0 Lsr2 Lyase_1 PF00206.20 GAX28331.1 - 3.2e-102 342.1 0.1 4.3e-102 341.7 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GAX28331.1 - 1.8e-25 89.1 1.4 1.8e-23 82.7 0.1 3.2 3 0 0 3 3 3 1 Fumarase C C-terminus Aminotran_3 PF00202.21 GAX28332.1 - 3.3e-116 388.3 0.0 3.8e-116 388.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAX28332.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TonB_2 PF13103.6 GAX28333.1 - 0.0093 16.2 0.1 0.021 15.1 0.0 1.6 2 0 0 2 2 2 1 TonB C terminal PhzC-PhzF PF02567.16 GAX28334.1 - 6.6e-13 48.8 0.1 1.1e-12 48.0 0.1 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein DNA_methylase PF00145.17 GAX28335.1 - 5e-34 118.1 0.0 6.1e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase RRM_1 PF00076.22 GAX28336.1 - 0.03 14.1 0.1 0.074 12.9 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 GAX28336.1 - 0.49 10.4 1.8 1.7 8.7 0.5 2.6 2 1 0 2 2 2 0 Surp module GMP_synt_C PF00958.22 GAX28337.1 - 1.3e-41 140.6 0.0 2.8e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 GAX28337.1 - 6.4e-38 130.4 0.1 1.6e-37 129.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAX28337.1 - 2.6e-11 43.7 0.0 4.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 GAX28337.1 - 9.9e-07 28.1 0.0 2.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 GAX28337.1 - 0.00041 20.0 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 GAX28337.1 - 0.0045 16.5 0.0 0.042 13.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAX28337.1 - 0.0072 15.2 0.1 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Arginosuc_synth PF00764.19 GAX28337.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 GAX28337.1 - 0.11 12.5 0.0 0.78 9.8 0.0 2.4 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 GAX28337.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 GAX28337.1 - 0.16 11.6 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Asparagine synthase zf-CHY PF05495.12 GAX28338.1 - 5.4e-17 62.1 15.4 5.4e-17 62.1 15.4 3.8 2 1 1 3 3 3 1 CHY zinc finger zinc_ribbon_6 PF14599.6 GAX28338.1 - 2.2e-16 59.6 1.3 2.2e-16 59.6 1.3 3.3 3 2 0 3 3 3 1 Zinc-ribbon zf-RING_2 PF13639.6 GAX28338.1 - 9.1e-09 35.5 7.9 9.1e-09 35.5 7.9 5.3 4 1 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 GAX28338.1 - 1.2e-05 25.1 9.0 1.2e-05 25.1 9.0 5.8 4 2 0 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX28338.1 - 0.00026 20.9 1.6 0.00026 20.9 1.6 4.6 3 2 1 4 4 4 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAX28338.1 - 0.00066 19.5 2.0 0.00066 19.5 2.0 5.7 5 1 1 6 6 6 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAX28338.1 - 0.0047 16.7 7.7 0.0047 16.7 7.7 5.5 4 3 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX28338.1 - 0.0062 16.4 2.1 0.0062 16.4 2.1 6.5 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 GAX28338.1 - 0.63 10.5 0.1 0.63 10.5 0.1 5.4 7 1 1 8 8 8 0 Zinc-finger of C2H2 type ShK PF01549.24 GAX28339.1 - 1.2e-12 48.1 11.2 3.5e-06 27.4 1.8 2.1 2 0 0 2 2 2 2 ShK domain-like Crisp PF08562.10 GAX28339.1 - 0.33 11.6 13.8 0.75 10.4 10.8 2.0 1 1 1 2 2 2 0 Crisp SLX9 PF15341.6 GAX28340.1 - 0.021 15.2 0.2 0.028 14.8 0.2 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF5345 PF17280.2 GAX28340.1 - 0.79 9.7 3.4 0.43 10.6 0.9 1.8 2 1 0 2 2 2 0 Family of unknown function (DUF5345) Atx10homo_assoc PF09759.9 GAX28342.1 - 1e-22 80.0 0.3 2.2e-17 62.9 0.1 3.5 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain IBN_N PF03810.19 GAX28342.1 - 0.014 15.3 0.2 0.056 13.4 0.2 2.1 1 0 0 1 1 1 0 Importin-beta N-terminal domain ATP_bind_1 PF03029.17 GAX28343.1 - 1.1e-67 228.3 0.1 1.5e-67 227.9 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 GAX28343.1 - 2.2e-07 31.4 0.0 5.4e-07 30.2 0.0 1.7 2 1 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAX28343.1 - 7.9e-07 29.1 0.2 0.045 13.7 0.4 3.1 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 GAX28343.1 - 1.5e-05 24.6 0.0 0.15 11.6 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 GAX28343.1 - 2e-05 24.2 0.0 0.00038 20.1 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAX28343.1 - 2.1e-05 24.5 0.0 0.00016 21.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX28343.1 - 0.00045 19.8 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.6 GAX28343.1 - 0.001 19.3 0.0 0.0032 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAX28343.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 GAX28343.1 - 0.0029 17.4 0.0 0.0073 16.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain G-alpha PF00503.20 GAX28343.1 - 0.0037 16.5 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit NB-ARC PF00931.22 GAX28343.1 - 0.0044 16.2 0.0 0.0093 15.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Ras PF00071.22 GAX28343.1 - 0.013 15.1 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Ras family MeaB PF03308.16 GAX28343.1 - 0.013 14.5 0.0 4.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 GAX28343.1 - 0.014 15.6 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 GAX28343.1 - 0.017 14.7 0.0 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 GAX28343.1 - 0.018 15.0 0.0 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 GAX28343.1 - 0.022 14.6 0.0 0.058 13.3 0.0 1.7 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GAX28343.1 - 0.024 14.8 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAX28343.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAX28343.1 - 0.032 14.3 0.3 0.092 12.8 0.0 1.9 2 1 0 2 2 2 0 Dynamin family KAP_NTPase PF07693.14 GAX28343.1 - 0.054 12.7 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_7 PF12775.7 GAX28343.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 GAX28343.1 - 0.086 12.6 0.0 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 GAX28343.1 - 0.089 13.3 0.0 0.31 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 GAX28343.1 - 0.096 12.6 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Phi_1 PF04674.12 GAX28343.1 - 0.12 11.6 0.1 1.4 8.2 0.0 2.0 1 1 1 2 2 2 0 Phosphate-induced protein 1 conserved region HSP90 PF00183.18 GAX28344.1 - 1.1e-157 526.1 7.6 1.4e-157 525.7 7.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAX28344.1 - 9.4e-12 45.4 0.2 2.3e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX28344.1 - 3.2e-09 36.7 0.0 8.2e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4579 PF15158.6 GAX28345.1 - 0.014 15.2 0.3 0.027 14.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) RRM_1 PF00076.22 GAX28346.1 - 1.9e-24 85.2 0.0 7.3e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAX28346.1 - 0.01 15.9 0.1 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif DDHD PF02862.17 GAX28346.1 - 0.044 13.9 0.5 0.047 13.9 0.5 1.2 1 0 0 1 1 1 0 DDHD domain Asparaginase_2 PF01112.18 GAX28346.1 - 0.09 11.8 0.2 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 Asparaginase PRP1_N PF06424.12 GAX28346.1 - 0.41 11.0 16.1 2.8 8.3 1.4 3.1 2 1 1 3 3 3 0 PRP1 splicing factor, N-terminal Med19 PF10278.9 GAX28346.1 - 0.9 9.5 11.8 1.6 8.7 11.8 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 GAX28346.1 - 0.92 8.2 2.7 1.2 7.9 2.7 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_C1 PF00112.23 GAX28347.1 - 1.2e-41 143.2 13.3 1.7e-40 139.5 13.3 2.4 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAX28347.1 - 6.8e-12 45.6 2.7 1.3e-11 44.7 2.7 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Surp PF01805.20 GAX28348.1 - 2.4e-28 97.9 6.2 8.6e-15 54.5 0.6 2.9 3 0 0 3 3 3 2 Surp module PRP21_like_P PF12230.8 GAX28348.1 - 1e-23 84.4 19.4 3.4e-15 56.5 2.9 3.3 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 GAX28348.1 - 7.1e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Acyl-thio_N PF12590.8 GAX28348.1 - 0.051 14.1 0.5 0.2 12.2 0.3 2.1 2 0 0 2 2 2 0 Acyl-ATP thioesterase GUN4 PF05419.12 GAX28349.1 - 4.6e-45 153.1 0.0 5.7e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 GUN4-like TLC PF03219.14 GAX28350.1 - 3.2e-182 606.6 1.9 3.9e-182 606.4 1.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter PMP1_2 PF08114.11 GAX28350.1 - 0.11 12.3 0.9 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 ATPase proteolipid family DUF3784 PF12650.7 GAX28350.1 - 0.11 12.7 0.2 0.11 12.7 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) ThiF PF00899.21 GAX28351.1 - 7.9e-65 218.6 0.0 7.4e-58 195.8 0.0 3.7 2 1 1 3 3 3 3 ThiF family UBA_e1_thiolCys PF10585.9 GAX28351.1 - 1.2e-45 156.5 0.0 2.2e-45 155.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GAX28351.1 - 4e-14 53.1 0.0 1.1e-13 51.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GAX28351.1 - 6.7e-08 32.6 1.0 3.3e-07 30.4 0.4 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Pyr_redox_2 PF07992.14 GAX28351.1 - 0.13 11.5 0.0 0.3 10.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase APG6 PF04111.12 GAX28352.1 - 3.6e-10 40.1 0.1 2.7e-09 37.2 0.0 2.4 2 1 1 3 3 3 1 Apg6 BARA domain APG6_N PF17675.1 GAX28352.1 - 0.012 16.2 23.2 0.017 15.6 23.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 GAX28352.1 - 0.025 14.6 2.5 0.043 13.9 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) NCD3G PF07562.14 GAX28352.1 - 0.027 14.5 3.1 0.053 13.5 3.1 1.5 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Cep57_MT_bd PF06657.13 GAX28352.1 - 0.036 14.5 2.0 0.036 14.5 2.0 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Med25 PF11232.8 GAX28352.1 - 0.066 13.2 0.5 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 HMMR_N PF15905.5 GAX28352.1 - 0.18 11.2 14.7 0.28 10.6 14.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal AAA_13 PF13166.6 GAX28352.1 - 0.82 8.2 10.1 1.1 7.9 10.1 1.1 1 0 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.13 GAX28352.1 - 0.86 9.1 9.9 0.12 11.9 4.6 2.2 2 1 0 2 2 2 0 fzo-like conserved region TPR_MLP1_2 PF07926.12 GAX28352.1 - 1.2 9.2 20.9 6 6.9 20.9 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.17 GAX28352.1 - 1.7 8.6 9.9 7.8 6.4 2.8 2.5 1 1 1 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.19 GAX28352.1 - 2.5 5.9 6.3 3.1 5.6 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 GAX28352.1 - 2.8 7.9 17.6 1.3 9.0 2.9 3.3 1 1 2 3 3 3 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 GAX28352.1 - 5.3 7.2 20.4 0.22 11.7 10.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 MFS_1 PF07690.16 GAX28353.1 - 1e-16 60.8 13.0 3.4e-12 46.0 2.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX28353.1 - 0.0015 17.5 9.2 0.028 13.3 0.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter YdjM PF04307.14 GAX28353.1 - 0.058 12.7 0.0 0.2 10.9 0.1 1.7 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF983 PF06170.12 GAX28353.1 - 5.5 7.5 7.6 15 6.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Pkinase_Tyr PF07714.17 GAX28354.1 - 1.1e-35 123.2 0.1 3.5e-35 121.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GAX28354.1 - 1.3e-31 110.0 0.1 4.2e-31 108.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 GAX28354.1 - 0.21 11.5 0.3 0.56 10.1 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Adap_comp_sub PF00928.21 GAX28356.1 - 3.5e-15 56.1 0.0 5.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAX28356.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain DUF3720 PF12517.8 GAX28356.1 - 2.6 9.0 7.5 0.34 11.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) GRP PF07172.11 GAX28356.1 - 5.1 7.8 18.6 0.083 13.6 3.8 2.4 2 0 0 2 2 2 0 Glycine rich protein family Mcl1_mid PF12341.8 GAX28357.1 - 2.1e-69 234.1 0.0 5.2e-69 232.8 0.0 1.7 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 GAX28357.1 - 0.0005 20.8 0.9 1.7 9.6 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28357.1 - 0.001 19.4 0.0 0.41 11.0 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 GAX28357.1 - 0.34 10.2 2.6 0.55 9.5 2.6 1.3 1 0 0 1 1 1 0 BUD22 RDD PF06271.12 GAX28358.1 - 1.8e-18 67.1 2.9 2.7e-18 66.5 2.9 1.3 1 0 0 1 1 1 1 RDD family SAM_2 PF07647.17 GAX28358.1 - 0.17 12.0 0.1 3.4 7.8 0.0 2.5 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) Myb_DNA-binding PF00249.31 GAX28359.1 - 1.6e-13 50.6 0.3 2.7e-13 49.9 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX28359.1 - 4.8e-05 23.5 0.3 9e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAX28359.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Myb DNA-binding like PIP5K PF01504.18 GAX28360.1 - 1.7e-74 250.5 0.3 9.6e-74 248.0 0.3 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Phe_ZIP PF08916.11 GAX28360.1 - 0.062 14.0 0.6 0.22 12.3 0.6 1.9 1 0 0 1 1 1 0 Phenylalanine zipper HA PF03457.14 GAX28361.1 - 8.1e-137 445.7 28.1 2.9e-22 78.8 1.7 8.2 8 0 0 8 8 8 7 Helicase associated domain HBB PF06777.11 GAX28361.1 - 0.022 14.4 0.2 0.28 10.9 0.1 2.7 2 0 0 2 2 2 0 Helical and beta-bridge domain WD40 PF00400.32 GAX28362.1 - 2.2e-21 75.7 6.4 0.00027 21.7 0.2 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat FHA PF00498.26 GAX28362.1 - 6.7e-15 55.2 0.1 4e-14 52.7 0.1 2.4 2 0 0 2 2 2 1 FHA domain ANAPC4_WD40 PF12894.7 GAX28362.1 - 7e-10 39.1 0.0 0.0022 18.2 0.0 5.6 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Yop-YscD_cpl PF16697.5 GAX28362.1 - 2.1e-07 31.1 0.0 6.4e-06 26.4 0.0 3.2 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Nucleoporin_N PF08801.11 GAX28362.1 - 0.00018 20.4 0.0 0.66 8.7 0.0 3.4 3 1 1 4 4 4 2 Nup133 N terminal like CPSF_A PF03178.15 GAX28362.1 - 0.0014 18.1 0.0 0.013 14.8 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region Peptidase_C15 PF01470.17 GAX28363.1 - 1.5e-08 35.1 0.0 5.8e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Pyroglutamyl peptidase DUF2258 PF10015.9 GAX28364.1 - 0.066 13.3 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) DUF1736 PF08409.11 GAX28365.1 - 2.3e-20 72.3 1.2 6.4e-20 70.9 1.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) ANAPC3 PF12895.7 GAX28365.1 - 0.0055 16.9 0.0 0.02 15.1 0.0 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 HSF_DNA-bind PF00447.17 GAX28366.1 - 3.4e-19 69.2 0.0 6.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding baeRF_family2 PF18844.1 GAX28366.1 - 0.093 12.8 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Malic_M PF03949.15 GAX28367.1 - 2.3e-77 259.7 0.1 2.2e-74 250.0 0.1 2.3 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAX28367.1 - 1.6e-72 243.1 0.0 2.6e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF1415 PF07209.12 GAX28368.1 - 0.0067 16.2 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1415) DUF5372 PF17342.2 GAX28368.1 - 0.032 14.6 2.3 6.6 7.2 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5372) UEV PF05743.13 GAX28370.1 - 4.5e-26 91.1 0.1 1.5e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 GAX28370.1 - 1.4e-19 69.8 0.2 3e-19 68.7 0.2 1.6 1 0 0 1 1 1 1 Vps23 core domain PIN_2 PF10130.9 GAX28370.1 - 0.69 10.1 4.8 0.98 9.6 3.7 1.8 1 1 1 2 2 2 0 PIN domain Mitofilin PF09731.9 GAX28370.1 - 5.3 5.8 25.3 7.3 5.3 25.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein bZIP_1 PF00170.21 GAX28371.1 - 2e-09 37.4 9.2 2e-09 37.4 9.2 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAX28371.1 - 2.2e-05 24.9 6.3 2.2e-05 24.9 6.3 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 GAX28371.1 - 5.6e-05 23.1 14.8 5.6e-05 23.1 14.8 2.0 2 0 0 2 2 2 1 Basic region leucine zipper FapA PF03961.13 GAX28371.1 - 0.033 12.8 1.9 0.039 12.6 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tho2 PF11262.8 GAX28371.1 - 0.059 12.6 5.9 0.094 11.9 5.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FliD_N PF02465.18 GAX28371.1 - 0.11 13.2 0.3 0.11 13.2 0.3 2.4 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4407 PF14362.6 GAX28371.1 - 0.21 10.9 1.5 0.25 10.6 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SHE3 PF17078.5 GAX28371.1 - 0.3 10.8 5.7 1.6 8.4 1.5 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 GAX28371.1 - 0.44 9.9 7.9 0.92 8.8 7.9 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 GAX28371.1 - 0.5 8.2 2.0 0.55 8.1 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S64 PF08192.11 GAX28371.1 - 1.3 7.5 5.1 1.6 7.1 5.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 SR-25 PF10500.9 GAX28371.1 - 1.5 8.4 22.7 7.5 6.1 22.2 2.0 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 GAX28371.1 - 3.3 5.9 11.0 4.1 5.6 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Med21 PF11221.8 GAX28371.1 - 6.2 7.1 10.3 0.24 11.6 3.0 2.3 1 1 2 3 3 3 0 Subunit 21 of Mediator complex DUF3987 PF13148.6 GAX28371.1 - 9.3 5.1 12.9 1.1 8.2 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) Glyco_transf_25 PF01755.17 GAX28372.1 - 9.2e-15 55.0 0.0 2.7e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) SBF2 PF12335.8 GAX28373.1 - 8.5e-05 22.3 7.2 9.4e-05 22.1 1.8 3.1 2 1 0 2 2 2 1 Myotubularin protein DUF2688 PF10892.8 GAX28373.1 - 0.078 12.5 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) NUDIX PF00293.28 GAX28374.1 - 5.2e-17 62.1 0.0 7.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 GAX28374.1 - 6.9e-09 35.6 0.1 1.3e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain Ribosomal_L41 PF05162.13 GAX28375.1 - 1e-07 31.8 31.7 1.6e-07 31.3 31.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L41 ubiquitin PF00240.23 GAX28375.1 - 0.00021 21.0 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family FapA PF03961.13 GAX28375.1 - 0.052 12.1 0.0 0.053 12.1 0.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rad60-SLD PF11976.8 GAX28375.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SF3b1 PF08920.10 GAX28376.1 - 4.3e-27 95.0 15.3 4.1e-24 85.4 15.3 3.6 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 GAX28376.1 - 4.9e-12 46.1 2.9 0.21 12.0 0.0 6.8 6 0 0 6 6 6 3 HEAT repeats HEAT PF02985.22 GAX28376.1 - 3.9e-07 29.8 11.9 6 7.4 0.0 9.2 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 GAX28376.1 - 7.3e-07 29.6 4.1 0.083 13.4 0.0 7.2 7 1 1 8 8 8 1 HEAT-like repeat NUC173 PF08161.12 GAX28376.1 - 3.6e-05 23.5 0.6 0.78 9.4 0.0 4.5 5 0 0 5 5 5 2 NUC173 domain MMS19_C PF12460.8 GAX28376.1 - 0.00025 20.3 0.0 0.65 9.0 0.0 3.5 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal UME PF08064.13 GAX28376.1 - 0.0061 16.4 0.1 19 5.2 0.0 4.9 4 1 1 5 5 5 0 UME (NUC010) domain CLASP_N PF12348.8 GAX28376.1 - 0.061 12.9 0.3 1.8 8.1 0.0 2.6 3 0 0 3 3 3 0 CLASP N terminal DRIM PF07539.12 GAX28376.1 - 0.17 10.2 0.1 6.2 5.0 0.0 2.8 2 1 0 3 3 3 0 Down-regulated in metastasis Vac14_Fab1_bd PF12755.7 GAX28376.1 - 0.52 10.9 2.7 1.1e+02 3.5 0.1 4.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 GAX28378.1 - 4.8e-24 84.7 0.7 1.7e-23 83.0 0.1 2.4 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 GAX28378.1 - 0.00018 21.2 0.2 0.00065 19.4 0.0 2.0 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DNAJ_related PF12339.8 GAX28378.1 - 0.93 9.7 4.1 2.2 8.5 0.8 2.5 1 1 1 2 2 2 0 DNA-J related protein AIRC PF00731.20 GAX28379.1 - 1.5e-12 47.3 3.4 1.5e-12 47.3 3.4 1.9 2 0 0 2 2 2 1 AIR carboxylase AIF_C PF14721.6 GAX28379.1 - 0.16 12.4 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FKBP_C PF00254.28 GAX28380.1 - 1.4e-18 67.0 0.1 2.2e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RRN3 PF05327.11 GAX28381.1 - 3.3e-83 280.1 4.6 3.3e-83 280.1 4.6 2.4 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GAX28381.1 - 3.6 5.7 9.0 5.2 5.2 9.0 1.2 1 0 0 1 1 1 0 Nop14-like family U-box PF04564.15 GAX28382.1 - 1.1e-11 44.8 0.0 2.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain C2 PF00168.30 GAX28382.1 - 2e-07 31.2 0.0 1.4e-05 25.3 0.0 2.4 1 1 1 2 2 2 1 C2 domain zf-Nse PF11789.8 GAX28382.1 - 3.8e-05 23.4 0.0 7.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 GAX28382.1 - 0.028 14.6 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 GAX28382.1 - 0.079 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DHFR_1 PF00186.19 GAX28383.1 - 5e-08 32.8 0.2 8.9e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Dihydrofolate reductase Tom22 PF04281.13 GAX28384.1 - 4.5e-06 26.5 0.0 5.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 PAS PF00989.25 GAX28385.1 - 1.3e-07 31.6 0.0 5.2e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 GAX28385.1 - 2.5e-06 27.7 0.0 7.2e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 GAX28385.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 GAX28385.1 - 0.00065 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain DUF4570 PF15134.6 GAX28385.1 - 0.021 14.9 2.5 0.064 13.3 2.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) bZIP_2 PF07716.15 GAX28385.1 - 0.17 12.0 8.9 0.71 10.0 8.9 2.1 1 0 0 1 1 1 0 Basic region leucine zipper Serinc PF03348.15 GAX28386.1 - 3.3e-62 210.8 0.4 3.7e-62 210.6 0.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) SLT_beta PF02258.16 GAX28386.1 - 0.0089 16.0 0.1 0.023 14.7 0.1 1.7 1 0 0 1 1 1 1 Shiga-like toxin beta subunit DUF2649 PF10854.8 GAX28386.1 - 0.18 12.2 4.6 1.2 9.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2649) PI3_PI4_kinase PF00454.27 GAX28387.1 - 1.2e-34 120.3 0.0 1.8e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 GAX28387.1 - 0.0072 16.1 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family NUDIX PF00293.28 GAX28388.1 - 2.7e-09 37.2 0.1 3.9e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain OppC_N PF12911.7 GAX28388.1 - 0.051 13.6 0.1 0.051 13.6 0.1 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Ribosomal_L37 PF08561.10 GAX28388.1 - 0.11 13.0 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 SRP54 PF00448.22 GAX28389.1 - 1.1e-71 240.6 5.0 8e-64 214.9 0.2 3.0 2 1 1 3 3 3 2 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAX28389.1 - 3.1e-22 79.0 7.5 3.1e-22 79.0 7.5 3.2 4 0 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 GAX28389.1 - 1.3e-15 57.3 1.5 3e-15 56.2 0.3 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 GAX28389.1 - 2.7e-05 24.2 0.2 0.001 19.1 0.0 3.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 GAX28389.1 - 7.5e-05 22.1 0.1 0.0015 17.8 0.1 2.3 1 1 1 2 2 2 1 Zeta toxin AAA_33 PF13671.6 GAX28389.1 - 0.016 15.3 0.1 0.075 13.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAX28389.1 - 0.017 14.8 0.1 0.04 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAX28389.1 - 0.034 14.0 0.1 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.6 GAX28389.1 - 0.047 14.2 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX28389.1 - 0.14 12.4 0.0 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAX28389.1 - 0.14 11.8 0.3 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.6 GAX28389.1 - 0.24 10.9 3.2 3.2 7.3 3.1 2.6 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 GAX28389.1 - 4.1 6.5 9.0 8.4 5.5 0.0 4.0 3 1 1 4 4 4 0 Anion-transporting ATPase Ank_2 PF12796.7 GAX28391.1 - 1.4e-38 131.3 4.7 2.1e-13 50.6 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX28391.1 - 2.4e-35 120.5 2.7 6.2e-09 36.2 0.1 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX28391.1 - 2.6e-31 104.1 4.3 0.0026 18.1 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 GAX28391.1 - 3e-27 94.3 8.0 1.3e-06 28.5 0.2 7.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 GAX28391.1 - 2.8e-25 87.6 17.3 0.00077 19.8 0.1 8.9 9 0 0 9 9 9 6 Ankyrin repeat MATH PF00917.26 GAX28391.1 - 2.9e-12 46.7 0.0 1.3e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 MATH domain Syntaxin PF00804.25 GAX28392.1 - 1.1e-33 116.6 13.9 1.4e-33 116.3 13.9 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 GAX28392.1 - 2.3e-10 40.3 2.3 5.9e-10 39.0 2.3 1.7 1 0 0 1 1 1 1 SNARE domain Pepsin-I3 PF06394.13 GAX28392.1 - 0.017 15.3 0.8 0.017 15.3 0.8 2.3 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain Cas_DxTHG PF09455.10 GAX28392.1 - 0.16 11.5 10.5 0.12 12.0 9.2 1.4 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Herpes_US9 PF06072.11 GAX28392.1 - 0.2 11.5 1.1 0.51 10.2 0.5 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Syntaxin_2 PF14523.6 GAX28392.1 - 0.37 11.2 19.0 0.17 12.3 14.9 2.4 2 2 0 2 2 2 0 Syntaxin-like protein MCPsignal PF00015.21 GAX28392.1 - 0.4 10.5 5.7 14 5.4 0.4 3.2 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HigB-like_toxin PF05015.13 GAX28392.1 - 0.5 10.8 4.2 0.92 10.0 0.3 3.0 2 2 1 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB Serine_rich PF08824.10 GAX28392.1 - 0.7 9.9 7.1 0.49 10.4 3.0 2.5 2 1 1 3 3 3 0 Serine rich protein interaction domain T2SSF PF00482.23 GAX28392.1 - 0.98 9.4 6.4 4.1 7.4 0.9 3.1 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Equine_IAV_S2 PF06502.11 GAX28392.1 - 8.8 6.5 8.1 9.8 6.4 1.9 2.6 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein HEAT_2 PF13646.6 GAX28393.1 - 8.9e-24 83.7 5.8 2e-13 50.5 1.5 3.6 2 1 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 GAX28393.1 - 8e-20 69.5 8.7 0.00054 20.4 0.0 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 GAX28393.1 - 0.0002 21.7 1.6 5.6 7.6 0.0 4.5 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 GAX28393.1 - 0.00051 20.1 8.3 1.4 9.4 0.2 4.9 5 0 0 5 5 5 2 HEAT repeat PSK_trans_fac PF07704.11 GAX28393.1 - 0.36 11.6 2.3 0.57 11.0 0.4 2.3 2 0 0 2 2 2 0 Rv0623-like transcription factor GST_N_3 PF13417.6 GAX28394.1 - 1e-10 41.8 0.0 2.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAX28394.1 - 2e-08 34.3 0.1 3.8e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.20 GAX28394.1 - 4.9e-06 26.8 0.1 8.7e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX28394.1 - 6.1e-06 26.2 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAX28394.1 - 1.7e-05 25.0 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAX28394.1 - 0.001 19.8 0.1 0.0025 18.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Pep_deformylase PF01327.21 GAX28395.1 - 9.6e-50 168.3 0.0 1.1e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase PGAP1 PF07819.13 GAX28397.1 - 3e-07 30.4 0.0 7.3e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAX28397.1 - 5e-07 29.4 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 GAX28397.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 GAX28397.1 - 0.00083 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 GAX28397.1 - 0.0077 16.9 0.3 0.029 15.0 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 GAX28397.1 - 0.043 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 GAX28397.1 - 0.069 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cutinase PF01083.22 GAX28397.1 - 0.16 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Cutinase LCAT PF02450.15 GAX28397.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase WD40_4 PF16300.5 GAX28398.1 - 4.4e-18 64.9 0.3 8.1e-18 64.0 0.3 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 GAX28398.1 - 5.4e-16 58.2 0.0 1.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 GAX28398.1 - 1.9e-14 53.8 3.7 0.0004 21.1 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28398.1 - 1.5e-08 34.8 0.0 0.026 14.8 0.0 4.2 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF745 PF05335.13 GAX28398.1 - 0.0026 17.5 1.7 0.0042 16.8 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) CCDC144C PF14915.6 GAX28398.1 - 0.0063 15.7 3.0 0.0089 15.2 3.0 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region ATG16 PF08614.11 GAX28398.1 - 0.015 15.5 1.7 0.022 15.0 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 GAX28398.1 - 0.017 15.2 1.4 0.028 14.4 1.4 1.3 1 0 0 1 1 1 0 Laminin Domain II DHR10 PF18595.1 GAX28398.1 - 0.019 15.0 3.3 0.031 14.4 3.3 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tmemb_cc2 PF10267.9 GAX28398.1 - 0.03 13.5 0.1 0.041 13.0 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Spc7 PF08317.11 GAX28398.1 - 0.048 12.5 5.1 0.072 12.0 5.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 GAX28398.1 - 0.053 13.8 0.9 0.1 12.9 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Fzo_mitofusin PF04799.13 GAX28398.1 - 0.25 10.9 1.5 0.37 10.3 1.5 1.2 1 0 0 1 1 1 0 fzo-like conserved region Borrelia_P83 PF05262.11 GAX28398.1 - 0.25 9.8 5.1 0.39 9.2 5.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.14 GAX28398.1 - 0.37 11.1 6.6 0.64 10.3 6.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NBP1 PF08537.10 GAX28398.1 - 0.46 9.9 3.2 0.63 9.4 3.2 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Exonuc_VII_S PF02609.16 GAX28398.1 - 1.3 9.2 6.3 2.5 8.2 6.3 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit XhlA PF10779.9 GAX28398.1 - 3.8 7.8 5.9 6.4 7.1 5.9 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Acyltransferase PF01553.21 GAX28399.1 - 6.6e-27 93.8 0.0 1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase BT1 PF03092.16 GAX28400.1 - 1.1e-32 113.0 16.0 2.8e-20 72.1 6.7 3.5 1 1 2 3 3 3 2 BT1 family PUCC PF03209.15 GAX28400.1 - 3.5e-11 42.7 0.2 3.5e-11 42.7 0.2 1.7 2 0 0 2 2 2 1 PUCC protein MFS_1 PF07690.16 GAX28400.1 - 2.7e-09 36.4 12.2 2.7e-09 36.4 12.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nucleoporin_N PF08801.11 GAX28401.1 - 1.4e-42 146.0 0.0 4.9e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 Nup133 N terminal like Nucleoporin_C PF03177.14 GAX28401.1 - 2.8e-18 66.0 2.4 4.3e-18 65.4 2.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Aminotran_5 PF00266.19 GAX28402.1 - 1.5e-27 96.6 0.0 4.8e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V ATP_bind_3 PF01171.20 GAX28402.1 - 0.0094 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 PP-loop family XhlA PF10779.9 GAX28403.1 - 7.5 6.8 7.5 0.97 9.7 0.5 3.3 3 0 0 3 3 3 0 Haemolysin XhlA Sulfate_transp PF00916.20 GAX28404.1 - 3.4e-25 88.6 13.5 5.3e-25 88.0 13.5 1.3 1 0 0 1 1 1 1 Sulfate permease family Pre-PUA PF17832.1 GAX28405.1 - 5.4e-24 84.7 0.3 7.8e-24 84.2 0.3 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 GAX28405.1 - 3.2e-16 59.0 0.0 6.7e-16 58.0 0.0 1.5 1 1 0 1 1 1 1 PUA domain 2OG-FeII_Oxy_2 PF13532.6 GAX28406.1 - 2.6e-16 60.4 0.1 4.9e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX28406.1 - 0.037 14.5 0.1 0.071 13.6 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Period_C PF12114.8 GAX28407.1 - 0.04 13.5 0.8 0.087 12.4 0.8 1.6 1 1 0 1 1 1 0 Period protein 2/3C-terminal region DUF1344 PF07076.11 GAX28407.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) HATPase_c PF02518.26 GAX28408.1 - 6.4e-18 65.3 0.0 1.5e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 GAX28408.1 - 0.018 15.7 0.1 0.047 14.3 0.1 1.7 2 0 0 2 2 2 0 GAF domain HATPase_c_3 PF13589.6 GAX28408.1 - 0.026 14.4 0.3 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 GAX28408.1 - 0.032 14.6 0.0 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 GAF domain GAF_2 PF13185.6 GAX28408.1 - 0.043 14.1 0.0 0.27 11.5 0.0 2.3 3 0 0 3 3 3 0 GAF domain HisKA PF00512.25 GAX28408.1 - 0.076 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Ion_trans PF00520.31 GAX28409.1 - 3.4e-08 33.0 6.1 2.7e-07 30.1 3.6 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 GAX28409.1 - 0.0001 22.7 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair PKD_channel PF08016.12 GAX28409.1 - 0.0034 16.1 2.8 0.0065 15.2 2.8 1.5 1 0 0 1 1 1 1 Polycystin cation channel DEAD PF00270.29 GAX28410.1 - 3.7e-32 111.5 1.0 1.1e-31 110.0 0.5 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX28410.1 - 2.4e-26 92.2 0.6 3.5e-22 78.9 0.1 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28410.1 - 1.6e-07 31.5 0.0 5.8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 GAX28410.1 - 5.3e-05 22.1 0.0 0.00016 20.5 0.0 1.6 1 1 0 2 2 2 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 GAX28410.1 - 0.00054 19.7 0.0 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 SWI2/SNF2 ATPase SecA_DEAD PF07517.14 GAX28410.1 - 0.0011 18.3 0.0 0.018 14.3 0.0 2.3 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_30 PF13604.6 GAX28410.1 - 0.024 14.3 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain TF_Zn_Ribbon PF08271.12 GAX28411.1 - 2e-11 43.2 0.5 4.2e-11 42.2 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2935 PF11155.8 GAX28411.1 - 0.0024 18.2 2.6 0.29 11.5 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF2935) zf-RRN7 PF11781.8 GAX28411.1 - 0.13 12.0 1.1 0.27 11.0 1.1 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CCDC92 PF14916.6 GAX28411.1 - 6.8 6.6 10.2 0.11 12.3 2.6 2.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF1517 PF07466.11 GAX28412.1 - 1.1e-39 136.4 0.0 1.5e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) Limkain-b1 PF11608.8 GAX28412.1 - 0.91 9.6 3.2 29 4.8 1.5 2.9 2 1 0 2 2 2 0 Limkain b1 Spermine_synth PF01564.17 GAX28413.1 - 5.6e-63 211.8 0.0 8.1e-63 211.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GAX28413.1 - 1.3e-23 82.6 0.1 2.3e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAX28413.1 - 1.5e-05 25.6 0.0 5.9e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28413.1 - 4.5e-05 23.3 0.0 6.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX28413.1 - 0.03 15.0 0.0 0.078 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.7 GAX28414.1 - 8.3e-18 65.8 0.1 1.1e-17 65.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX28414.1 - 1.4e-15 57.2 0.0 3.6e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX28414.1 - 1e-13 51.6 0.0 1.1e-12 48.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX28414.1 - 0.00061 19.3 0.0 0.0023 17.5 0.0 1.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family DTC PF18102.1 GAX28414.1 - 0.0052 16.9 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 Deltex C-terminal domain Ser_hydrolase PF06821.13 GAX28414.1 - 0.0079 16.1 0.0 0.067 13.0 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_8 PF06259.12 GAX28414.1 - 0.047 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_5 PF12695.7 GAX28414.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family TPR_2 PF07719.17 GAX28415.1 - 3.9e-09 35.9 0.1 0.55 10.5 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAX28415.1 - 1.9e-05 24.7 1.5 0.16 12.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX28415.1 - 6.4e-05 23.2 7.5 0.55 10.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28415.1 - 0.00026 20.7 0.1 0.041 13.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX28415.1 - 0.0022 18.1 0.0 0.089 13.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 GAX28415.1 - 0.13 12.4 0.0 0.49 10.5 0.0 2.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 GAX28415.1 - 0.15 12.7 0.2 51 4.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX28415.1 - 0.17 12.0 0.4 52 4.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 GAX28417.1 - 7.1e-39 133.6 1.7 1.1e-38 133.0 0.0 2.1 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 GAX28417.1 - 9.9e-14 52.0 21.5 7.5e-13 49.2 20.6 2.3 1 1 1 2 2 2 1 SYF2 splicing factor Acyl-CoA_dh_1 PF00441.24 GAX28417.1 - 0.056 13.7 0.4 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain MRP-S27 PF10037.9 GAX28417.1 - 0.62 8.9 10.2 0.92 8.3 10.2 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Nic96 PF04097.14 GAX28418.1 - 1.6e-32 112.8 0.0 6.8e-32 110.7 0.0 1.8 1 1 0 1 1 1 1 Nup93/Nic96 TNF PF00229.18 GAX28418.1 - 0.033 14.1 0.1 0.2 11.6 0.1 2.2 3 0 0 3 3 3 0 TNF(Tumour Necrosis Factor) family Utp11 PF03998.13 GAX28419.1 - 1.5e-63 215.1 29.8 1.8e-63 214.7 29.8 1.1 1 0 0 1 1 1 1 Utp11 protein DUF357 PF04010.13 GAX28419.1 - 0.32 11.1 0.0 0.32 11.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF357) Redoxin PF08534.10 GAX28420.1 - 8e-15 54.8 0.0 2e-14 53.5 0.0 1.6 1 1 1 2 2 2 1 Redoxin peroxidase PF00141.23 GAX28421.1 - 2.3e-44 151.8 0.0 3e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase zf-RING_11 PF17123.5 GAX28422.1 - 2e-06 27.4 5.5 0.0014 18.3 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 GAX28422.1 - 1.3e-05 25.0 5.5 1.3e-05 24.9 1.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX28422.1 - 2.8e-05 24.0 0.1 0.00011 22.1 0.1 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAX28422.1 - 3.6e-05 24.0 12.5 0.00054 20.2 12.5 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAX28422.1 - 6.9e-05 22.8 2.3 0.00013 21.9 0.3 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAX28422.1 - 0.0002 21.6 15.6 0.1 13.0 15.6 3.5 1 1 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 GAX28422.1 - 0.002 17.9 0.1 0.0041 16.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 GAX28422.1 - 0.002 17.9 6.9 0.005 16.7 0.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAX28422.1 - 0.004 17.2 5.7 0.49 10.5 5.7 2.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAX28422.1 - 0.077 12.6 0.1 0.077 12.6 0.1 1.9 3 0 0 3 3 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 GAX28422.1 - 0.15 12.2 1.7 2 8.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger Prok-RING_4 PF14447.6 GAX28422.1 - 0.17 11.8 2.9 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 GAX28422.1 - 0.41 10.8 8.9 11 6.2 8.9 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain PHD_4 PF16866.5 GAX28422.1 - 0.46 10.6 3.7 1.5 9.0 3.7 1.9 1 0 0 1 1 1 0 PHD-finger Tmpp129 PF10272.9 GAX28422.1 - 0.79 9.0 8.9 0.8 8.9 4.4 2.7 3 0 0 3 3 3 0 Putative transmembrane protein precursor zf-C3HC4_4 PF15227.6 GAX28422.1 - 1.3 9.3 9.1 18 5.6 0.1 3.7 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GAX28422.1 - 1.6 8.6 5.6 1.4 8.8 0.4 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAX28422.1 - 4.6 7.4 8.3 70 3.7 8.4 2.9 1 1 0 1 1 1 0 RING-variant domain ANAPC1 PF12859.7 GAX28424.1 - 1.1e-08 35.7 0.1 0.0018 18.8 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 GAX28424.1 - 0.087 13.3 0.0 0.087 13.3 0.0 5.5 6 0 0 6 6 6 0 Proteasome/cyclosome repeat MCM PF00493.23 GAX28426.1 - 1e-69 234.1 0.0 5.7e-65 218.6 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 GAX28426.1 - 3.3e-22 78.7 2.6 4.3e-22 78.3 0.5 2.1 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 GAX28426.1 - 1.2e-18 67.3 0.4 1.2e-18 67.3 0.4 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAX28426.1 - 3.6e-08 33.0 0.1 3.9e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX28426.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX28426.1 - 0.0059 17.0 0.4 0.082 13.3 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain MCM_N PF14551.6 GAX28426.1 - 0.02 15.5 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain AAA_22 PF13401.6 GAX28426.1 - 0.04 14.2 0.1 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAX28426.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 GAX28426.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 GAX28426.1 - 0.088 12.5 0.0 0.86 9.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 GAX28426.1 - 0.091 12.5 0.1 0.24 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAX28426.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.9 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain XendoU PF09412.10 GAX28427.1 - 9.5e-93 310.2 0.0 1.4e-92 309.7 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 GAX28427.1 - 0.032 14.6 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial EndoU nuclease DUF1350 PF07082.11 GAX28428.1 - 1.7e-23 83.3 0.0 3.2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1350) Bromodomain PF00439.25 GAX28429.1 - 7.9e-17 61.1 0.1 2e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Bromodomain PBP_sp32 PF07222.12 GAX28429.1 - 3.8 6.9 6.8 6.3 6.2 6.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ank_5 PF13857.6 GAX28431.1 - 1.3e-18 66.8 0.0 4.2e-08 33.3 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX28431.1 - 1.7e-16 60.6 0.0 9.8e-08 32.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX28431.1 - 1.6e-13 49.5 0.3 0.17 12.5 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 GAX28431.1 - 7.5e-12 45.5 0.4 0.17 12.5 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAX28431.1 - 1.9e-10 40.7 2.5 1.1 9.9 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ion_trans PF00520.31 GAX28431.1 - 3.7e-08 32.9 18.2 6.5e-08 32.1 18.2 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GAX28431.1 - 0.0063 15.2 2.1 0.0063 15.2 2.1 2.7 3 0 0 3 3 3 2 Polycystin cation channel Peptidase_C54 PF03416.19 GAX28432.1 - 1.2e-74 251.2 0.0 1.7e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 GAX28432.1 - 0.028 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C78 ubiquitin PF00240.23 GAX28433.1 - 1.4e-17 63.1 0.0 3.2e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX28433.1 - 5.1e-06 26.2 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HNH_3 PF13392.6 GAX28433.1 - 0.03 14.1 1.2 0.073 12.8 1.2 1.7 1 0 0 1 1 1 0 HNH endonuclease AP3D1 PF06375.11 GAX28433.1 - 0.031 14.5 13.9 0.67 10.2 10.4 2.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 CTNNB1_binding PF08347.11 GAX28433.1 - 2.5 8.3 6.2 0.78 9.9 0.4 2.6 2 0 0 2 2 2 0 N-terminal CTNNB1 binding ATG11 PF10377.9 GAX28434.1 - 3.2e-18 66.0 0.0 1.3e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.12 GAX28434.1 - 9.3e-08 31.6 16.9 9.4e-07 28.3 13.2 3.3 2 1 0 2 2 2 1 Autophagy protein Apg17 Syntaxin_2 PF14523.6 GAX28434.1 - 0.014 15.7 8.0 0.57 10.6 0.9 2.9 1 1 1 2 2 2 0 Syntaxin-like protein LXG PF04740.12 GAX28434.1 - 0.057 13.1 8.6 0.11 12.2 8.0 1.8 1 1 0 1 1 1 0 LXG domain of WXG superfamily Terminase_2 PF03592.16 GAX28434.1 - 0.059 13.8 3.6 0.22 12.0 3.2 2.1 2 0 0 2 2 2 0 Terminase small subunit DUF5101 PF17031.5 GAX28434.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) DUF2458 PF10454.9 GAX28434.1 - 0.19 11.4 7.0 3.2 7.4 2.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) Ku_PK_bind PF08785.11 GAX28434.1 - 0.28 11.3 3.6 1.9 8.7 2.8 2.6 1 1 0 1 1 1 0 Ku C terminal domain like ZYG-11_interact PF05884.12 GAX28434.1 - 0.35 10.2 1.7 0.67 9.3 1.7 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 CTK3_C PF12350.8 GAX28434.1 - 0.57 10.4 3.7 1.1 9.5 0.4 2.5 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus LMBR1 PF04791.16 GAX28434.1 - 0.84 8.5 5.9 1.5 7.6 5.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein AATF-Che1 PF13339.6 GAX28434.1 - 1.7 9.4 9.5 18 6.0 5.4 3.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Cortex-I_coil PF09304.10 GAX28434.1 - 4.5 7.5 11.9 5.5 7.2 0.2 3.3 3 1 0 3 3 3 0 Cortexillin I, coiled coil PRK PF00485.18 GAX28435.1 - 2.2e-36 125.5 0.0 2.8e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAX28435.1 - 1.8e-05 25.3 0.1 3e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAX28435.1 - 7.1e-05 23.3 1.7 0.18 12.3 1.1 2.4 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 GAX28435.1 - 0.00019 20.8 0.0 0.00057 19.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 GAX28435.1 - 0.00039 20.6 0.0 0.00099 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 GAX28435.1 - 0.00055 19.6 0.4 0.22 11.2 0.0 2.3 2 0 0 2 2 2 1 Dephospho-CoA kinase dNK PF01712.19 GAX28435.1 - 0.00057 19.8 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase ABC_tran PF00005.27 GAX28435.1 - 0.0012 19.3 0.0 0.0018 18.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 GAX28435.1 - 0.0019 18.5 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 GAX28435.1 - 0.0038 17.0 0.6 0.48 10.1 0.0 2.2 1 1 1 2 2 2 1 Cytidylate kinase AAA_28 PF13521.6 GAX28435.1 - 0.0039 17.4 0.1 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX28435.1 - 0.0049 16.8 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Roc PF08477.13 GAX28435.1 - 0.0054 16.9 0.1 0.77 10.0 0.0 2.4 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 GAX28435.1 - 0.0056 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.14 GAX28435.1 - 0.0061 16.4 0.1 0.029 14.3 0.0 2.1 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 GAX28435.1 - 0.0076 16.3 0.0 0.017 15.2 0.0 1.5 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 GAX28435.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 GAX28435.1 - 0.019 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.27 GAX28435.1 - 0.026 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ADK PF00406.22 GAX28435.1 - 0.035 14.2 0.7 2.2 8.4 0.2 2.3 2 0 0 2 2 2 0 Adenylate kinase DUF2075 PF09848.9 GAX28435.1 - 0.047 12.9 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 GAX28435.1 - 0.054 13.9 0.1 0.12 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 GAX28435.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase DUF87 PF01935.17 GAX28435.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_19 PF13245.6 GAX28435.1 - 0.068 13.5 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAX28435.1 - 0.078 13.1 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 GAX28435.1 - 0.082 12.6 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 GAX28435.1 - 0.098 11.9 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_7 PF12775.7 GAX28435.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 GAX28435.1 - 0.11 12.2 0.0 0.34 10.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 GAX28435.1 - 0.11 12.4 0.5 0.22 11.5 0.4 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 GAX28435.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Lipase_3 PF01764.25 GAX28436.1 - 1.5e-12 47.5 0.0 3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) CLP_protease PF00574.23 GAX28437.1 - 3.7e-80 268.1 0.2 4.7e-80 267.8 0.2 1.1 1 0 0 1 1 1 1 Clp protease HMA PF00403.26 GAX28438.1 - 0.0024 18.3 0.3 0.016 15.6 0.3 2.1 1 1 0 1 1 1 1 Heavy-metal-associated domain DUF294 PF03445.13 GAX28438.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 LMF1 PF06762.14 GAX28439.1 - 3.3e-121 405.5 18.3 3e-63 214.5 7.1 2.1 1 1 1 2 2 2 2 Lipase maturation factor DoxX PF07681.12 GAX28439.1 - 0.032 14.8 0.9 0.067 13.8 0.0 2.0 2 0 0 2 2 2 0 DoxX RRM_1 PF00076.22 GAX28440.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF438 PF04282.13 GAX28440.1 - 0.22 11.5 1.0 0.4 10.7 0.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF438) COesterase PF00135.28 GAX28441.1 - 2.4e-104 350.0 0.1 1.2e-88 298.2 0.0 3.5 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 GAX28441.1 - 7.1e-08 32.6 0.1 8.9e-07 29.0 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX28441.1 - 0.014 14.8 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_U32 PF01136.19 GAX28441.1 - 0.077 12.1 0.3 0.32 10.1 0.0 2.1 3 0 0 3 3 3 0 Peptidase family U32 FmiP_Thoc5 PF09766.9 GAX28442.1 - 6.1e-23 81.7 8.3 4.8e-19 68.9 3.2 3.1 2 1 0 2 2 2 2 Fms-interacting protein/Thoc5 CENP-B_N PF04218.13 GAX28442.1 - 0.28 10.8 2.5 0.31 10.7 0.2 2.2 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain TFA2_Winged_2 PF18121.1 GAX28443.1 - 4.4e-08 32.7 0.0 2.9e-07 30.1 0.0 2.4 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 GAX28443.1 - 0.0019 18.5 0.0 0.01 16.1 0.0 2.3 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF1406 PF07190.11 GAX28444.1 - 0.079 12.9 0.1 17 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1406) Sigma70_ECF PF07638.11 GAX28444.1 - 0.42 10.5 7.1 3.4 7.5 1.1 3.3 3 0 0 3 3 3 0 ECF sigma factor IFP_35_N PF07334.13 GAX28444.1 - 1.1 9.4 5.6 3.8 7.6 5.1 2.3 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HEPN PF05168.14 GAX28444.1 - 5.9 7.0 11.8 6.7 6.9 2.2 3.3 2 1 1 3 3 3 0 HEPN domain DUF3228 PF11539.8 GAX28445.1 - 6.9e-79 263.9 0.0 7.9e-79 263.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Acyl-CoA_dh_1 PF00441.24 GAX28446.1 - 1.7e-44 151.7 4.2 3e-44 150.8 4.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX28446.1 - 1.3e-36 125.6 0.4 5.8e-36 123.6 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAX28446.1 - 7.8e-27 93.3 0.1 1.5e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAX28446.1 - 8.6e-19 68.1 4.0 1.6e-18 67.3 4.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAX28446.1 - 0.013 15.1 0.2 0.036 13.7 0.0 1.8 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.6 GAX28446.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal DUF1995 PF09353.10 GAX28447.1 - 8.5e-39 133.6 0.0 1e-38 133.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) HD_4 PF13328.6 GAX28449.1 - 0.068 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 HD domain BRCA-2_OB3 PF09104.10 GAX28449.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Peptidase_C97 PF05903.14 GAX28451.1 - 2.2e-29 102.2 0.0 3.2e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain HMG_box PF00505.19 GAX28452.1 - 2.3e-40 136.9 21.3 2.5e-21 75.9 2.8 2.6 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX28452.1 - 1.5e-26 92.8 17.2 4e-16 59.4 2.6 2.7 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.12 GAX28452.1 - 4.4e-06 26.5 0.0 0.068 13.1 0.0 2.5 2 0 0 2 2 2 2 CHDNT (NUC034) domain HMG_box_5 PF14887.6 GAX28452.1 - 2.2e-05 24.3 10.1 0.0017 18.3 0.5 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box 5 YABBY PF04690.13 GAX28452.1 - 5.6e-05 23.8 11.2 0.055 14.0 0.5 2.3 1 1 1 2 2 2 2 YABBY protein RR_TM4-6 PF06459.12 GAX28452.1 - 0.0015 18.4 11.9 0.05 13.4 7.9 2.1 1 1 0 2 2 2 2 Ryanodine Receptor TM 4-6 HTH_WhiA PF02650.14 GAX28452.1 - 0.023 15.0 0.2 15 6.0 0.0 2.9 2 1 1 3 3 3 0 WhiA C-terminal HTH domain NACHT PF05729.12 GAX28452.1 - 0.064 13.2 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF1264 PF06884.11 GAX28452.1 - 0.083 12.5 0.6 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1264) Ccdc124 PF06244.12 GAX28452.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.4 1 1 3 4 4 4 0 Coiled-coil domain-containing protein 124 /Oxs1 GEN1_C PF18380.1 GAX28452.1 - 2.1 9.3 17.5 4.3 8.3 7.1 2.5 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Aa_trans PF01490.18 GAX28453.1 - 6e-50 170.1 8.2 7.4e-50 169.8 8.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAX28453.1 - 1.3e-10 40.9 2.6 1.3e-10 40.9 2.6 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Aminotran_5 PF00266.19 GAX28454.1 - 1.5e-34 119.6 0.0 7.7e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V TTL PF03133.15 GAX28454.1 - 6.1e-20 71.5 0.0 1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAX28454.1 - 0.0022 17.3 0.0 0.0087 15.3 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp 2OG-FeII_Oxy_2 PF13532.6 GAX28455.1 - 2.8e-17 63.6 0.0 7.3e-17 62.2 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 GAX28455.1 - 2.2e-10 41.0 0.0 5.9e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX28455.1 - 2.4e-09 37.8 0.0 1.1e-08 35.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX28455.1 - 0.00049 20.8 0.0 0.0013 19.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX28455.1 - 0.0036 17.2 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 GAX28455.1 - 0.043 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF727 PF05303.12 GAX28455.1 - 0.14 12.2 0.1 9 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF727) DEAD PF00270.29 GAX28456.1 - 1.1e-37 129.5 0.1 5.2e-37 127.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX28456.1 - 2.3e-19 69.8 0.4 7.3e-19 68.1 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28456.1 - 0.00031 20.8 0.0 0.00088 19.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAX28456.1 - 0.047 12.5 0.3 0.53 9.0 0.1 2.5 3 1 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Methyltransf_21 PF05050.12 GAX28458.1 - 6.2e-13 49.1 0.0 9.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 GAX28458.1 - 0.089 12.1 0.0 0.18 11.0 0.0 1.4 1 1 0 1 1 1 0 Vibrio cholerae RfbT protein Kelch_1 PF01344.25 GAX28459.1 - 1.4e-24 85.4 2.6 2e-07 30.4 0.2 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAX28459.1 - 2e-17 62.9 9.3 5.9e-05 23.0 0.1 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAX28459.1 - 8.2e-16 57.7 9.3 0.00034 20.8 0.0 6.6 4 2 2 6 6 6 4 Kelch motif Kelch_5 PF13854.6 GAX28459.1 - 7.1e-15 54.6 6.0 1.3e-05 25.1 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 GAX28459.1 - 3.7e-13 49.4 12.5 0.0017 18.6 0.1 5.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAX28459.1 - 3.6e-05 23.6 5.7 0.22 11.6 0.2 5.8 6 2 0 6 6 6 2 Kelch motif Epimerase PF01370.21 GAX28460.1 - 2.5e-12 46.8 0.0 1.9e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX28460.1 - 0.0035 17.2 0.0 0.024 14.5 0.0 2.4 1 1 1 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAX28460.1 - 0.044 12.9 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain FAD_binding_3 PF01494.19 GAX28461.1 - 1.5e-19 70.4 0.0 4.3e-10 39.4 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAX28461.1 - 1e-07 31.9 0.4 5.7e-07 29.4 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX28461.1 - 1.6e-05 24.2 0.1 2.4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 GAX28461.1 - 8.3e-05 21.8 0.0 0.0028 16.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 GAX28461.1 - 0.00019 21.6 0.2 0.0021 18.2 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAX28461.1 - 0.00036 19.1 0.0 0.00049 18.6 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAX28461.1 - 0.00098 18.4 0.2 0.0019 17.5 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX28461.1 - 0.0017 17.7 0.0 0.0073 15.6 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAX28461.1 - 0.0078 15.6 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX28461.1 - 0.015 14.0 0.3 0.03 13.1 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 GAX28461.1 - 0.037 13.1 0.1 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAX28461.1 - 0.058 12.2 0.2 5.8 5.7 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.18 GAX28461.1 - 0.062 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ion_trans_2 PF07885.16 GAX28462.1 - 1.8e-31 107.9 10.7 9.4e-19 67.2 5.6 2.3 2 0 0 2 2 2 2 Ion channel EF-hand_5 PF13202.6 GAX28462.1 - 4.3e-10 38.6 1.7 3.5e-06 26.3 0.0 3.3 2 1 1 3 3 3 2 EF hand EF-hand_1 PF00036.32 GAX28462.1 - 6e-09 34.8 1.7 0.00016 21.0 0.1 3.1 2 1 1 3 3 3 2 EF hand EF-hand_7 PF13499.6 GAX28462.1 - 9.7e-09 35.6 0.2 0.0015 18.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX28462.1 - 5.1e-07 29.1 1.0 0.012 15.5 0.0 2.8 1 1 2 3 3 3 2 EF-hand domain Ion_trans PF00520.31 GAX28462.1 - 0.002 17.4 0.7 0.077 12.2 0.1 2.3 2 1 0 2 2 2 1 Ion transport protein EF-hand_8 PF13833.6 GAX28462.1 - 0.0044 16.8 0.9 0.028 14.3 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain pair Dockerin_1 PF00404.18 GAX28462.1 - 0.2 11.9 0.0 0.7 10.1 0.0 1.8 2 0 0 2 2 2 0 Dockerin type I domain HemY_N PF07219.13 GAX28462.1 - 0.22 11.7 5.8 6.5 7.0 1.3 2.7 1 1 1 2 2 2 0 HemY protein N-terminus ATP-synt_DE PF00401.20 GAX28462.1 - 2.2 8.6 9.5 0.22 11.8 4.9 1.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Metallophos PF00149.28 GAX28463.1 - 3.9e-05 24.3 0.1 4.8e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BSD PF03909.17 GAX28464.1 - 0.00035 20.5 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 BSD domain DUF3512 PF12024.8 GAX28464.1 - 0.078 12.5 1.3 0.15 11.5 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3512) Josephin PF02099.17 GAX28464.1 - 0.8 9.8 0.1 0.8 9.8 0.1 2.2 3 0 0 3 3 3 0 Josephin Pribosyltran_N PF13793.6 GAX28465.1 - 4.2e-50 168.5 0.3 1.7e-49 166.6 0.0 2.2 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAX28465.1 - 5.7e-26 91.7 0.1 2.5e-25 89.6 0.1 2.0 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAX28465.1 - 9.3e-13 48.0 0.2 2e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAX28465.1 - 0.092 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase adh_short PF00106.25 GAX28466.1 - 1.8e-24 86.3 0.0 1.9e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28466.1 - 2.9e-13 49.9 0.0 1.1e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX28466.1 - 2.6e-05 24.2 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX28466.1 - 0.01 15.3 0.0 0.086 12.3 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Adenine_deam_C PF13382.6 GAX28466.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain PseudoU_synth_2 PF00849.22 GAX28467.1 - 2.7e-13 50.3 0.0 7e-13 49.0 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase ACPS PF01648.20 GAX28468.1 - 1.2e-10 41.5 0.0 2.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily QH-AmDH_gamma PF08992.11 GAX28468.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit PCIF1_WW PF12237.8 GAX28469.1 - 1.2e-37 129.2 0.0 2.5e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain BRAP2 PF07576.12 GAX28469.1 - 0.097 12.9 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 BRCA1-associated protein 2 Ribosomal_L27A PF00828.19 GAX28470.1 - 8.9e-23 81.4 0.2 8.9e-23 81.4 0.2 1.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 GAX28470.1 - 0.094 12.8 0.6 0.16 12.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) DUF4460 PF14687.6 GAX28471.1 - 3.6e-05 23.8 0.2 8.5e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) ABC_tran PF00005.27 GAX28472.1 - 1e-30 107.0 0.0 2.6e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAX28472.1 - 4.4e-28 98.7 4.2 3.1e-27 95.9 4.2 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 GAX28472.1 - 1.4e-06 28.3 1.8 0.035 13.9 1.7 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX28472.1 - 3.5e-05 23.4 0.1 0.00017 21.1 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAX28472.1 - 9.2e-05 22.1 0.2 0.0003 20.5 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 GAX28472.1 - 0.00048 19.9 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 GAX28472.1 - 0.0011 19.6 0.0 0.0032 18.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAX28472.1 - 0.015 15.2 0.2 0.038 13.9 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 GAX28472.1 - 0.021 14.4 0.2 0.76 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAX28472.1 - 0.03 14.7 1.6 0.14 12.5 0.1 2.7 2 2 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 GAX28472.1 - 0.049 12.9 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 GAX28472.1 - 0.11 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAX28472.1 - 0.14 12.4 0.5 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 GAX28472.1 - 0.17 12.1 1.2 0.57 10.3 0.0 2.6 3 1 0 3 3 3 0 AAA domain PAP_fibrillin PF04755.12 GAX28473.1 - 1.4e-13 51.2 0.2 6.2e-13 49.1 0.2 2.0 1 1 0 1 1 1 1 PAP_fibrillin CC2D2AN-C2 PF15625.6 GAX28474.1 - 0.09 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain DUF2589 PF11655.8 GAX28474.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) PPR_2 PF13041.6 GAX28475.1 - 9.4e-15 54.5 0.4 4.9e-05 23.4 0.0 6.8 7 1 0 7 7 7 2 PPR repeat family PPR_1 PF12854.7 GAX28475.1 - 5.2e-05 22.8 2.8 3.4 7.4 0.0 5.5 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 GAX28475.1 - 0.00034 20.6 0.1 5.1 7.2 0.0 5.7 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.20 GAX28475.1 - 0.0026 17.9 7.4 0.022 15.0 0.0 5.5 8 0 0 8 8 8 1 PPR repeat Presenilin PF01080.17 GAX28476.1 - 1.5e-105 353.3 0.2 2.7e-105 352.4 0.2 1.4 1 1 0 1 1 1 1 Presenilin TPR_19 PF14559.6 GAX28477.1 - 1.7e-05 25.2 0.7 1.2 9.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28477.1 - 2.3e-05 24.0 3.2 0.03 14.2 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28477.1 - 3.5e-05 23.6 1.8 0.14 12.3 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX28477.1 - 8.8e-05 22.4 3.6 0.31 11.4 0.3 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX28477.1 - 0.0015 19.2 1.5 4.3 8.1 0.0 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX28477.1 - 0.003 18.2 0.2 1.4 9.9 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX28477.1 - 0.0048 16.6 0.9 1.8 8.3 0.1 3.2 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 GAX28477.1 - 0.024 14.9 0.1 2.2 8.6 0.1 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAX28477.1 - 0.042 14.1 0.6 3.1 8.1 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAX28477.1 - 0.06 12.8 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR TPR_7 PF13176.6 GAX28477.1 - 0.098 12.7 1.5 8.4 6.7 0.2 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX28477.1 - 0.13 13.0 0.0 21 6.1 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MatP_C PF17414.2 GAX28477.1 - 2.4 8.4 4.9 0.81 9.9 0.4 2.5 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain Glyoxalase PF00903.25 GAX28478.1 - 1.5e-07 31.7 0.0 1.3e-05 25.4 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAX28478.1 - 5.7e-07 29.8 0.0 0.0023 18.2 0.0 2.7 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GAX28478.1 - 1.4e-05 25.3 1.1 0.0023 18.1 0.1 2.8 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 GAX28478.1 - 0.01 15.9 1.1 2.3 8.3 0.3 3.4 3 1 0 3 3 3 0 Glyoxalase-like domain Aminotran_1_2 PF00155.21 GAX28479.1 - 2.1e-44 152.2 0.0 2.6e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 GAX28479.1 - 0.0038 16.2 0.1 0.0094 14.9 0.1 1.4 1 1 0 1 1 1 1 Allinase Mito_carr PF00153.27 GAX28480.1 - 7.7e-43 144.4 3.3 3.2e-15 55.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 GAX28480.1 - 0.011 16.2 4.4 0.11 12.9 2.9 2.6 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 GAX28480.1 - 0.29 11.3 6.5 11 6.2 0.1 4.2 4 0 0 4 4 4 0 LydA holin phage, holin superfamily III DUF4011 PF13195.6 GAX28481.1 - 0.015 15.2 0.7 0.042 13.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Syja_N PF02383.18 GAX28482.1 - 4.9e-56 190.4 0.0 1.3e-55 188.9 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain UreD PF01774.17 GAX28482.1 - 0.017 15.0 0.0 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 UreD urease accessory protein Rieske PF00355.26 GAX28482.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain COG7 PF10191.9 GAX28483.1 - 1.9e-51 175.3 1.3 2.6e-43 148.3 1.5 2.0 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) baeRF_family6 PF18848.1 GAX28483.1 - 0.023 15.1 0.1 0.045 14.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 NDK PF00334.19 GAX28484.1 - 5.9e-51 172.0 0.0 8.1e-51 171.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PIGA PF08288.12 GAX28485.1 - 2e-38 130.9 1.2 7.1e-38 129.1 0.1 2.5 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 GAX28485.1 - 3e-31 108.7 0.6 4.9e-31 108.0 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 GAX28485.1 - 1.8e-23 82.9 0.0 3.6e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX28485.1 - 4.1e-22 79.0 1.1 1.1e-21 77.7 0.4 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAX28485.1 - 1.1e-14 55.2 0.1 1.9e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX28485.1 - 0.0011 19.4 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GAX28485.1 - 0.024 14.4 0.1 0.057 13.1 0.1 1.7 1 1 0 1 1 1 0 Starch synthase catalytic domain RRM_1 PF00076.22 GAX28486.1 - 0.0005 19.8 0.0 0.0078 16.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 GAX28487.1 - 1.1e-15 58.4 0.1 1.1e-15 58.4 0.1 2.9 2 2 0 2 2 2 1 SET domain PHD PF00628.29 GAX28487.1 - 0.00019 21.3 46.6 0.00047 20.0 6.6 5.6 5 1 1 6 6 6 4 PHD-finger FANCL_C PF11793.8 GAX28487.1 - 0.0038 17.4 3.2 0.0038 17.4 3.2 3.8 5 0 0 5 5 5 1 FANCL C-terminal domain PHD_2 PF13831.6 GAX28487.1 - 0.023 14.3 1.4 0.023 14.3 1.4 6.2 6 0 0 6 6 6 0 PHD-finger C1_1 PF00130.22 GAX28487.1 - 0.039 13.9 0.4 0.039 13.9 0.4 4.7 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNF2_N PF00176.23 GAX28488.1 - 2.6e-38 131.6 0.0 5e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX28488.1 - 2e-17 63.5 0.0 1.2e-16 61.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28488.1 - 3.1e-05 24.0 0.2 0.0025 17.8 0.0 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 GAX28488.1 - 0.092 12.9 0.3 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Helicase C-terminal domain ABC_tran PF00005.27 GAX28489.1 - 1.1e-51 175.0 0.1 1.2e-24 87.4 0.1 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAX28489.1 - 4.2e-16 59.6 8.9 0.00011 22.1 0.0 4.7 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX28489.1 - 3.8e-12 46.1 4.6 3.4e-06 26.7 0.3 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 GAX28489.1 - 8.4e-11 41.8 3.9 1.5e-09 37.7 0.7 2.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 GAX28489.1 - 7e-07 28.9 1.3 0.0051 16.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX28489.1 - 3.3e-06 27.8 3.5 0.016 15.7 0.1 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAX28489.1 - 4.7e-06 26.7 0.2 0.033 14.3 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 GAX28489.1 - 3.6e-05 24.0 1.1 0.11 12.7 0.1 3.0 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 GAX28489.1 - 5e-05 23.4 2.9 0.0045 17.1 0.1 2.7 2 1 0 2 2 2 1 Dynamin family MeaB PF03308.16 GAX28489.1 - 8.2e-05 21.7 0.2 0.25 10.3 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 GAX28489.1 - 8.6e-05 22.5 0.4 0.012 15.5 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 GAX28489.1 - 0.00051 20.6 0.4 1.9 9.0 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX28489.1 - 0.00058 20.2 9.4 0.0082 16.4 0.3 4.2 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAX28489.1 - 0.00059 19.9 0.1 3.3 7.8 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 GAX28489.1 - 0.0011 19.3 0.2 0.19 12.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX28489.1 - 0.0014 18.4 0.4 2.3 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAX28489.1 - 0.0014 18.4 1.7 0.86 9.2 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Arf PF00025.21 GAX28489.1 - 0.0015 18.1 0.5 0.7 9.3 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family SbcCD_C PF13558.6 GAX28489.1 - 0.0024 18.0 0.8 4.1 7.7 0.0 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 GAX28489.1 - 0.0028 17.9 0.9 0.71 10.1 0.1 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 GAX28489.1 - 0.0048 16.7 0.3 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAX28489.1 - 0.0057 15.9 1.8 1.1 8.4 0.1 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 GAX28489.1 - 0.007 16.8 4.9 0.47 10.8 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 GAX28489.1 - 0.0085 15.9 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_27 PF13514.6 GAX28489.1 - 0.0097 15.5 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAX28489.1 - 0.012 16.0 0.2 1.5 9.2 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 GAX28489.1 - 0.038 14.4 0.7 17 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 GAX28489.1 - 0.042 13.4 6.4 0.34 10.5 0.3 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 GAX28489.1 - 0.044 12.6 0.2 0.15 10.8 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF815 PF05673.13 GAX28489.1 - 0.047 12.9 0.1 0.84 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Spore_IV_A PF09547.10 GAX28489.1 - 0.097 11.6 0.1 5.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) ATP_bind_1 PF03029.17 GAX28489.1 - 0.098 12.4 1.4 7.8 6.2 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 GAX28489.1 - 0.11 12.9 0.0 8.3 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 GAX28489.1 - 0.12 11.6 0.3 2 7.6 0.1 2.3 2 0 0 2 2 2 0 Septin AAA_13 PF13166.6 GAX28489.1 - 0.13 10.9 3.7 11 4.6 0.1 3.7 3 1 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 GAX28489.1 - 0.15 11.3 0.1 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 GAX28489.1 - 0.3 10.4 0.7 69 2.7 0.0 3.4 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GAX28489.1 - 0.42 10.5 2.6 20 5.1 0.3 2.4 2 0 0 2 2 2 0 NACHT domain dNK PF01712.19 GAX28489.1 - 1.4 8.7 3.5 26 4.6 0.2 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Androgen_recep PF02166.16 GAX28490.1 - 1.3 7.8 6.0 2.6 6.8 6.0 1.4 1 0 0 1 1 1 0 Androgen receptor PseudoU_synth_2 PF00849.22 GAX28491.1 - 5.9e-24 85.0 1.6 1.8e-16 60.7 0.0 2.4 2 1 0 2 2 2 2 RNA pseudouridylate synthase XhlA PF10779.9 GAX28492.1 - 0.45 10.7 2.9 0.65 10.2 0.2 2.4 2 0 0 2 2 2 0 Haemolysin XhlA RRM_1 PF00076.22 GAX28493.1 - 6.7e-17 61.1 2.7 1.8e-12 46.9 0.3 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 GAX28493.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.6 GAX28493.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ATP-synt_C PF00137.21 GAX28494.1 - 1.5e-34 118.2 37.3 5.4e-23 81.1 16.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PDZ PF00595.24 GAX28495.1 - 8e-07 29.3 0.7 1.9e-06 28.1 0.7 1.6 1 0 0 1 1 1 1 PDZ domain PT PF04886.12 GAX28495.1 - 0.0036 16.8 2.0 0.0036 16.8 2.0 4.5 2 1 2 4 4 4 2 PT repeat PDZ_6 PF17820.1 GAX28495.1 - 0.0053 16.6 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX28495.1 - 0.0071 16.6 0.8 0.017 15.4 0.8 1.7 1 0 0 1 1 1 1 PDZ domain HATPase_c PF02518.26 GAX28496.1 - 4.6e-09 36.8 0.0 8.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAX28496.1 - 0.0055 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAX28496.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain BCDHK_Adom3 PF10436.9 GAX28496.1 - 0.079 12.8 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase PDZ PF00595.24 GAX28497.1 - 9.2e-06 25.9 0.1 2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX28497.1 - 5.1e-05 23.0 0.0 9.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX28497.1 - 0.00022 21.5 0.1 0.00064 20.0 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAX28498.1 - 4.9e-06 26.8 1.6 1.5e-05 25.3 1.6 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX28498.1 - 0.00043 20.1 0.1 0.001 18.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX28498.1 - 0.00056 20.2 2.2 0.0011 19.2 2.2 1.5 1 0 0 1 1 1 1 PDZ domain DUF3117 PF11314.8 GAX28498.1 - 0.048 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) Alpha_kinase PF02816.18 GAX28499.1 - 1.7e-32 113.0 1.4 3.4e-18 66.4 0.5 2.4 2 0 0 2 2 2 2 Alpha-kinase family VWA_2 PF13519.6 GAX28499.1 - 0.0017 19.0 0.0 0.0045 17.6 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain PT PF04886.12 GAX28500.1 - 0.00027 20.4 12.6 0.00027 20.4 12.6 3.2 2 1 1 3 3 3 1 PT repeat PDZ_6 PF17820.1 GAX28500.1 - 0.038 13.8 0.1 0.08 12.8 0.1 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 GAX28500.1 - 0.048 14.0 0.2 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 PDZ domain YjgF_endoribonc PF14588.6 GAX28501.1 - 8.7e-29 100.6 0.0 9.9e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 GAX28501.1 - 1.6e-17 63.6 0.0 2.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP EF-hand_1 PF00036.32 GAX28503.1 - 0.0057 16.1 1.4 2 8.1 0.0 4.6 4 0 0 4 4 4 1 EF hand PspA_IM30 PF04012.12 GAX28503.1 - 5.1 6.6 9.8 2.4 7.7 0.9 3.1 3 0 0 3 3 3 0 PspA/IM30 family LRR_4 PF12799.7 GAX28504.1 - 4.4e-05 23.7 1.3 7.7 7.1 0.0 4.2 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX28504.1 - 0.0097 16.3 0.7 1.4e+02 3.6 0.0 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat Glycos_transf_3 PF00591.21 GAX28505.1 - 5.7e-87 291.5 0.0 9.3e-87 290.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 GAX28505.1 - 8e-17 60.9 0.1 2.1e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Taxilin PF09728.9 GAX28507.1 - 1.2e-07 31.3 7.2 1.2e-07 31.3 7.2 4.2 2 1 1 3 3 3 1 Myosin-like coiled-coil protein Cep57_MT_bd PF06657.13 GAX28507.1 - 0.0052 17.2 0.6 0.0052 17.2 0.6 7.2 5 2 2 8 8 8 2 Centrosome microtubule-binding domain of Cep57 Fer4_24 PF18109.1 GAX28507.1 - 0.87 9.9 3.7 0.48 10.7 0.2 2.5 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain DPM3 PF08285.11 GAX28507.1 - 1.3 9.3 3.7 13 6.0 0.2 2.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Spc7 PF08317.11 GAX28507.1 - 1.7 7.5 90.0 0.73 8.7 11.5 4.5 2 1 1 4 4 4 0 Spc7 kinetochore protein FAM209 PF15206.6 GAX28507.1 - 2.7 7.8 6.1 0.48 10.2 1.0 2.4 2 1 0 2 2 2 0 FAM209 family SMN PF06003.12 GAX28507.1 - 2.8 7.2 13.3 0.13 11.5 5.0 2.6 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) bHLH-MYC_N PF14215.6 GAX28508.1 - 9.3e-06 26.0 0.0 2.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal GAF_2 PF13185.6 GAX28508.1 - 0.026 14.8 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 GAF domain Spore_GerAC PF05504.11 GAX28508.1 - 0.15 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal bHLH-MYC_N PF14215.6 GAX28509.1 - 3.6e-05 24.1 0.7 0.00028 21.2 0.0 2.4 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal Vma12 PF11712.8 GAX28510.1 - 1.4e-12 47.9 0.2 3.3e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Adeno_E3_CR2 PF02439.15 GAX28510.1 - 0.23 11.2 1.4 0.65 9.8 1.4 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DNA_pol_E_B PF04042.16 GAX28511.1 - 7.5e-29 100.6 0.2 1.5e-28 99.6 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Cyclin_C PF02984.19 GAX28512.1 - 2.3e-07 30.9 0.4 2.3e-07 30.9 0.4 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 GAX28512.1 - 6.4e-07 29.2 0.0 2e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAE PF03283.13 GAX28512.1 - 0.12 11.5 0.4 0.52 9.4 0.1 1.9 1 1 1 2 2 2 0 Pectinacetylesterase Peptidase_S28 PF05577.12 GAX28514.1 - 4.1e-42 144.5 0.1 2.6e-32 112.2 0.0 3.2 2 1 0 2 2 2 2 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 GAX28514.1 - 0.0043 16.4 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAX28514.1 - 0.0044 16.5 0.2 0.012 15.1 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAX28514.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX28514.1 - 0.019 15.6 0.0 0.019 15.6 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family BTB PF00651.31 GAX28515.1 - 6.9e-06 26.3 1.3 0.00018 21.7 0.2 2.8 2 1 0 2 2 2 1 BTB/POZ domain Ran-binding PF05508.11 GAX28515.1 - 0.0016 17.5 4.1 0.0028 16.7 3.8 1.5 1 1 0 1 1 1 1 RanGTP-binding protein DUF745 PF05335.13 GAX28515.1 - 0.063 13.0 6.9 0.11 12.1 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BRE1 PF08647.11 GAX28515.1 - 0.07 13.2 7.5 0.25 11.5 7.5 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FAM76 PF16046.5 GAX28515.1 - 0.15 11.3 1.8 0.33 10.3 1.8 1.5 1 0 0 1 1 1 0 FAM76 protein DUF2935 PF11155.8 GAX28515.1 - 0.28 11.5 2.7 0.33 11.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Snapin_Pallidin PF14712.6 GAX28515.1 - 1.4 9.4 9.1 1.1 9.8 6.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin THOC7 PF05615.13 GAX28515.1 - 1.4 9.2 10.2 2.2 8.5 9.3 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 PEP-utilisers_N PF05524.13 GAX28515.1 - 3.4 7.9 5.8 3.8 7.7 1.2 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal LRR_6 PF13516.6 GAX28516.1 - 5.8e-09 35.3 11.2 0.0032 17.4 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_5 PF13306.6 GAX28516.1 - 0.00098 19.1 0.1 0.7 9.9 0.0 2.6 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 GAX28516.1 - 0.028 14.9 0.3 0.13 12.8 0.1 5.5 3 3 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX28516.1 - 0.7 10.7 9.1 5.8 7.9 0.0 6.0 6 2 0 6 6 6 0 Leucine Rich Repeat NifU PF01106.17 GAX28517.1 - 1.2e-27 95.9 0.2 1.8e-27 95.3 0.2 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 GAX28517.1 - 4.9e-25 87.4 0.0 1.2e-24 86.2 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal Ank_2 PF12796.7 GAX28518.1 - 3.1e-10 40.5 0.0 7.2e-05 23.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX28518.1 - 2e-08 33.8 1.5 0.018 15.5 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 GAX28518.1 - 4.3e-06 26.9 0.1 0.042 14.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAX28518.1 - 7.4e-05 23.0 0.5 0.061 13.7 0.2 3.5 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX28518.1 - 0.00073 20.1 0.1 0.029 15.0 0.0 3.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Pkinase PF00069.25 GAX28519.1 - 4.7e-38 131.1 0.0 1.2e-36 126.5 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX28519.1 - 3e-29 102.1 0.0 1.1e-28 100.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX28519.1 - 0.0033 16.8 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAX28519.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAA_hydrolase PF01557.18 GAX28520.1 - 1.6e-54 184.9 0.0 2.3e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAX28520.1 - 1.4e-20 73.4 0.0 2.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N PF02798.20 GAX28520.1 - 6.3e-13 48.9 0.0 1.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAX28520.1 - 1.3e-12 48.0 0.0 3.1e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX28520.1 - 1.7e-10 41.0 0.0 3.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAX28520.1 - 0.041 14.6 0.0 0.089 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain CNDH2_C PF16858.5 GAX28521.1 - 8.1e-61 206.5 0.2 8.1e-61 206.5 0.2 1.6 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 GAX28521.1 - 1.9e-30 105.3 0.9 3.3e-29 101.4 0.0 2.4 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Mito_carr PF00153.27 GAX28522.1 - 8.5e-53 176.3 0.6 1.6e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX28522.1 - 0.064 12.4 0.5 4.7 6.3 0.0 2.8 2 1 0 3 3 3 0 Gammaproteobacterial serine protease DUF4600 PF15372.6 GAX28523.1 - 0.031 14.7 1.4 0.86 10.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) CREPT PF16566.5 GAX28523.1 - 0.04 14.1 0.2 0.052 13.7 0.2 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Rota_VP2 PF05087.12 GAX28523.1 - 0.067 11.3 0.9 0.072 11.2 0.9 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein EnY2 PF10163.9 GAX28523.1 - 0.088 13.2 0.9 0.16 12.3 0.9 1.5 1 1 0 1 1 1 0 Transcription factor e(y)2 Chloroa_b-bind PF00504.21 GAX28524.1 - 3.1e-24 86.3 0.1 1.2e-23 84.4 0.1 1.8 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX28525.1 - 3.2e-27 96.0 0.0 1.2e-26 94.2 0.0 1.8 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Atg8 PF02991.16 GAX28527.1 - 9.5e-49 163.9 0.0 1.1e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GAX28527.1 - 6.7e-06 26.4 0.0 8.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Exo_endo_phos PF03372.23 GAX28528.1 - 4.3e-08 33.0 0.1 8.3e-07 28.8 0.1 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_isomerase PF00160.21 GAX28529.1 - 3.3e-10 40.5 0.0 6.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sulfotransfer_3 PF13469.6 GAX28530.1 - 0.00031 21.2 0.1 0.022 15.2 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Trypsin PF00089.26 GAX28531.1 - 5e-44 150.7 0.0 7.3e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin 2OG-FeII_Oxy_3 PF13640.6 GAX28532.1 - 0.012 16.5 0.0 0.058 14.3 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily GFO_IDH_MocA PF01408.22 GAX28533.1 - 1.1e-07 32.7 0.0 2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Dicty_REP PF05086.12 GAX28534.1 - 0.3 9.0 1.8 0.31 9.0 1.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CBS PF00571.28 GAX28536.1 - 6.1e-19 68.2 0.7 4.8e-11 42.9 0.3 2.4 2 1 0 2 2 2 2 CBS domain NETI PF14044.6 GAX28536.1 - 0.16 11.7 0.1 0.44 10.3 0.1 1.7 1 0 0 1 1 1 0 NETI protein SNF2_N PF00176.23 GAX28537.1 - 1.2e-37 129.5 0.2 3.4e-37 128.0 0.2 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX28537.1 - 1e-21 77.4 0.1 3.6e-21 75.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28537.1 - 3e-06 27.3 0.0 8.4e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAX28537.1 - 1.1e-05 24.7 0.2 6.1e-05 22.3 0.1 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 GAX28537.1 - 0.0002 20.6 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DALR_2 PF09190.11 GAX28537.1 - 0.087 13.3 0.0 25 5.4 0.0 3.5 3 0 0 3 3 3 0 DALR domain SWI2_SNF2 PF18766.1 GAX28537.1 - 0.16 11.6 0.4 0.37 10.4 0.0 1.9 2 1 0 2 2 2 0 SWI2/SNF2 ATPase S-methyl_trans PF02574.16 GAX28538.1 - 1.6e-55 188.8 0.1 2e-55 188.5 0.1 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Peptidase_M75 PF09375.10 GAX28538.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Imelysin DUF1749 PF08538.10 GAX28541.1 - 1.1e-53 182.3 0.0 1.3e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 GAX28541.1 - 3.1e-05 24.7 0.5 4.2e-05 24.3 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 GAX28541.1 - 0.00054 19.4 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 GAX28541.1 - 0.00092 19.1 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 GAX28541.1 - 0.0013 18.1 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 GAX28541.1 - 0.021 14.4 0.0 0.052 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) DUF900 PF05990.12 GAX28541.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1295 PF06966.12 GAX28542.1 - 2.9e-27 95.7 7.9 4.4e-27 95.1 7.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Methyltransf_28 PF02636.17 GAX28545.1 - 1.1e-27 97.3 0.1 2e-27 96.5 0.1 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 GAX28545.1 - 0.00021 22.0 0.0 0.00046 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28545.1 - 0.025 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAX28545.1 - 0.035 14.8 0.0 0.1 13.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 GAX28545.1 - 0.063 12.4 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF4315 PF14193.6 GAX28546.1 - 0.037 14.0 0.2 0.066 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) SPO22 PF08631.10 GAX28546.1 - 0.084 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like AAA_12 PF13087.6 GAX28547.1 - 6.9e-43 146.6 0.0 1.3e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX28547.1 - 6.6e-29 101.5 0.0 1.9e-28 100.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAX28547.1 - 3e-12 47.1 0.0 4.6e-11 43.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAX28547.1 - 6.5e-12 45.6 0.6 1.5e-07 31.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.21 GAX28547.1 - 7.2e-06 25.7 0.0 0.00014 21.5 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 GAX28547.1 - 0.00013 21.4 0.0 0.0047 16.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 GAX28547.1 - 0.0023 18.0 0.0 0.0092 16.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.29 GAX28547.1 - 0.0038 17.7 0.2 0.2 12.0 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAX28547.1 - 0.026 14.5 0.1 0.16 11.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX28547.1 - 0.085 13.2 2.1 0.23 11.8 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 GAX28547.1 - 0.086 13.1 1.1 2.3 8.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain XRN_N PF03159.18 GAX28548.1 - 2.2e-36 125.5 0.0 5e-36 124.4 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Recombinase PF07508.13 GAX28548.1 - 0.14 12.6 0.1 0.37 11.2 0.1 1.7 1 0 0 1 1 1 0 Recombinase DUF1336 PF07059.12 GAX28549.1 - 0.084 12.9 0.0 0.7 9.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1336) PCMT PF01135.19 GAX28550.1 - 5.7e-54 183.0 0.0 7.9e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 GAX28550.1 - 2.7e-08 34.4 0.0 6.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28550.1 - 5.4e-08 32.8 0.0 1.1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX28550.1 - 1.2e-07 31.8 1.0 2.3e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX28550.1 - 4.2e-07 30.6 0.3 0.0015 19.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 GAX28550.1 - 1.8e-05 24.3 0.1 7.2e-05 22.3 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 GAX28550.1 - 1.8e-05 24.6 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 GAX28550.1 - 6.4e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa MTS PF05175.14 GAX28550.1 - 0.00016 21.2 0.0 0.00034 20.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 GAX28550.1 - 0.0003 21.4 0.0 0.00085 19.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX28550.1 - 0.0022 17.4 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 GAX28550.1 - 0.012 15.7 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF2547 PF10818.8 GAX28550.1 - 0.053 14.5 0.5 0.11 13.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Menin PF05053.13 GAX28550.1 - 0.061 11.7 0.9 0.083 11.2 0.9 1.1 1 0 0 1 1 1 0 Menin CheR PF01739.18 GAX28550.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 GAX28550.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CSG2 PF16965.5 GAX28550.1 - 0.19 10.6 0.3 0.26 10.2 0.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Secretin_N_2 PF07655.13 GAX28550.1 - 0.57 10.8 8.3 1.1 9.8 8.3 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Sec6 PF06046.13 GAX28551.1 - 4.6e-08 31.9 1.1 4.6e-08 31.9 1.1 1.7 2 1 0 2 2 2 1 Exocyst complex component Sec6 cIII PF08134.11 GAX28551.1 - 0.29 10.9 1.1 12 5.7 0.1 2.5 2 0 0 2 2 2 0 cIII protein family DUF1127 PF06568.11 GAX28551.1 - 2.3 8.0 7.4 0.17 11.6 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) ADH_zinc_N PF00107.26 GAX28552.1 - 5.8e-17 61.9 0.0 1.1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAX28552.1 - 4.7e-08 32.9 0.0 9.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DNA_pol3_delta2 PF13177.6 GAX28553.1 - 5.1e-10 39.4 0.0 7.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 GAX28553.1 - 3.1e-06 27.5 0.2 1.4e-05 25.4 0.0 2.2 3 0 0 3 3 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 GAX28553.1 - 0.00044 20.2 0.0 0.0011 18.9 0.0 1.7 2 1 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 GAX28553.1 - 0.0028 17.8 0.0 0.31 11.2 0.1 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 GAX28553.1 - 0.0041 17.5 0.3 0.014 15.8 0.3 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX28553.1 - 0.0079 16.6 0.0 0.034 14.5 0.0 2.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GAX28553.1 - 0.01 16.3 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 GAX28553.1 - 0.016 15.1 0.1 1.3 8.8 0.1 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein RsgA_GTPase PF03193.16 GAX28553.1 - 0.022 14.7 0.0 0.077 12.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase RuvB_N PF05496.12 GAX28553.1 - 0.023 14.4 0.0 0.89 9.3 0.0 2.8 2 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 GAX28553.1 - 0.043 14.3 0.0 0.078 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 GAX28553.1 - 0.08 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX28553.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAX28553.1 - 0.2 11.9 1.9 10 6.4 0.5 3.5 1 1 0 2 2 2 0 AAA domain PB1 PF00564.24 GAX28554.1 - 0.084 12.8 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 PB1 domain ANAPC_CDC26 PF10471.9 GAX28555.1 - 6.2e-09 36.6 0.1 8e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 adh_short PF00106.25 GAX28556.1 - 1.5e-49 168.1 0.1 2e-49 167.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28556.1 - 4.7e-39 134.3 0.2 6.2e-39 133.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX28556.1 - 5.4e-17 62.3 0.0 7.6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAX28556.1 - 1.7e-08 34.2 0.2 3e-07 30.2 0.0 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX28556.1 - 2.9e-07 30.2 0.1 4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 GAX28556.1 - 1.2e-06 29.0 0.3 4.1e-06 27.3 0.2 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 GAX28556.1 - 2e-06 27.8 1.0 1.4e-05 25.1 1.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAX28556.1 - 1.4e-05 25.4 0.1 2.1e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 GAX28556.1 - 3.1e-05 23.9 0.1 5.8e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAX28556.1 - 3.2e-05 23.4 0.1 0.0026 17.1 0.1 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 GAX28556.1 - 0.00015 21.4 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 GAX28556.1 - 0.00027 20.2 0.1 0.00039 19.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAX28556.1 - 0.00068 18.9 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAX28556.1 - 0.00071 18.8 0.1 0.035 13.3 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 GAX28556.1 - 0.0018 18.4 0.2 0.0037 17.3 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DarA_N PF18788.1 GAX28556.1 - 0.0021 18.1 0.1 0.0052 16.8 0.1 1.8 1 1 0 1 1 1 1 Defence against restriction A N-terminal THF_DHG_CYH_C PF02882.19 GAX28556.1 - 0.0035 16.7 0.4 0.026 13.9 0.0 2.3 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 GAX28556.1 - 0.0035 16.9 0.3 0.0083 15.7 0.2 1.7 2 0 0 2 2 2 1 NmrA-like family DFP PF04127.15 GAX28556.1 - 0.0086 15.9 0.6 0.021 14.6 0.6 1.8 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.15 GAX28556.1 - 0.014 15.5 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 GAX28556.1 - 0.035 14.5 0.1 0.072 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DapB_N PF01113.20 GAX28556.1 - 0.055 13.6 0.1 0.095 12.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DNTTIP1_dimer PF18192.1 GAX28556.1 - 0.12 12.8 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain PHD PF00628.29 GAX28558.1 - 8.8e-10 38.3 8.7 1.8e-09 37.3 8.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAX28558.1 - 0.00087 18.8 1.3 0.002 17.6 1.3 1.6 1 0 0 1 1 1 1 PHD-finger Cue1_U7BR PF18499.1 GAX28558.1 - 0.075 13.1 0.3 0.93 9.6 0.2 2.3 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 zf-HC5HC2H PF13771.6 GAX28558.1 - 0.41 10.9 7.8 0.98 9.7 7.8 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Adap_comp_sub PF00928.21 GAX28559.1 - 1.9e-08 34.1 0.1 2.9e-07 30.1 0.1 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Myco_19_kDa PF05481.12 GAX28559.1 - 0.12 12.7 0.0 0.53 10.6 0.0 2.0 2 1 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen H_lectin PF09458.10 GAX28560.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 H-type lectin domain Hydrolase_4 PF12146.8 GAX28561.1 - 3.3e-10 39.6 0.0 1.5e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX28561.1 - 7.9e-10 38.8 0.0 0.0015 18.2 0.0 2.7 2 1 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX28561.1 - 1.8e-07 32.0 0.2 3.4e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAX28561.1 - 6.3e-06 26.2 0.0 2.9e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 GAX28561.1 - 3.1e-05 24.0 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 GAX28561.1 - 0.00048 19.9 0.0 0.036 13.7 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) UPF0227 PF05728.12 GAX28561.1 - 0.0015 18.5 0.0 0.0049 16.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.21 GAX28561.1 - 0.0044 16.5 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 GAX28561.1 - 0.014 15.0 0.0 3.6 7.1 0.0 3.0 3 0 0 3 3 3 0 Dienelactone hydrolase family DAGAT PF03982.13 GAX28561.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GAX28561.1 - 0.024 14.2 0.0 0.17 11.5 0.0 2.2 1 1 0 1 1 1 0 Acyltransferase WD40 PF00400.32 GAX28562.1 - 5.2e-28 96.7 7.8 4.3e-06 27.3 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28562.1 - 2.3e-10 40.6 0.6 1.2e-05 25.5 0.0 5.0 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX28562.1 - 5.8e-05 22.6 3.7 0.12 11.7 0.0 3.6 2 1 2 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 GAX28562.1 - 0.0044 16.0 1.6 0.12 11.4 0.0 2.7 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAX28562.1 - 0.0045 15.7 0.7 2.2 6.8 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Frtz PF11768.8 GAX28562.1 - 0.012 14.0 0.5 0.15 10.3 0.4 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 GAX28562.1 - 0.045 14.2 0.1 24 5.6 0.1 3.8 3 0 0 3 3 3 0 PQQ-like domain VID27 PF08553.10 GAX28562.1 - 0.1 11.6 0.1 0.47 9.5 0.1 1.9 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Peptidase_C97 PF05903.14 GAX28563.1 - 1.4e-25 89.9 0.0 3.5e-25 88.6 0.0 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain ISN1 PF06437.11 GAX28564.1 - 7.9e-94 314.9 0.0 1e-93 314.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase CDP-OH_P_transf PF01066.21 GAX28565.1 - 1.2e-15 58.0 0.1 1.2e-15 58.0 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SNF2_N PF00176.23 GAX28566.1 - 7.5e-72 242.0 2.7 8.8e-72 241.7 0.6 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAX28566.1 - 2.6e-35 120.9 0.3 2.1e-34 118.0 0.3 2.8 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 GAX28566.1 - 1.8e-18 66.9 0.0 8.3e-18 64.8 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28566.1 - 6.7e-11 42.5 0.0 6.7e-11 42.5 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 GAX28566.1 - 2.6e-09 37.4 14.5 2.3e-08 34.3 1.0 3.7 3 0 0 3 3 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX28566.1 - 3.9e-08 33.8 2.0 3.9e-08 33.8 2.0 3.7 3 0 0 3 3 2 2 HMG-box domain DEAD PF00270.29 GAX28566.1 - 2.5e-05 24.1 0.0 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Mst1_SARAH PF11629.8 GAX28566.1 - 0.0062 16.6 0.5 0.034 14.2 0.5 2.3 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 HDA2-3 PF11496.8 GAX28566.1 - 0.008 15.4 0.0 0.008 15.4 0.0 2.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PilJ PF13675.6 GAX28566.1 - 0.023 14.7 0.5 0.12 12.4 0.5 2.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4988 PF16378.5 GAX28566.1 - 0.091 12.4 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function Toprim_4 PF13662.6 GAX28566.1 - 0.17 12.3 0.3 1.3 9.5 0.2 2.6 2 0 0 2 2 1 0 Toprim domain WW PF00397.26 GAX28567.1 - 8e-13 48.2 0.2 2e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 WW domain Sec16_C PF12931.7 GAX28567.1 - 3.8e-11 43.2 1.2 1.5e-09 37.9 1.2 2.9 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 GAX28567.1 - 1.8e-07 31.8 11.8 0.035 15.0 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Prp18 PF02840.15 GAX28567.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Prp18 domain TPR_1 PF00515.28 GAX28567.1 - 0.17 11.8 0.0 30 4.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat WHAMM-JMY_N PF15920.5 GAX28567.1 - 0.35 10.8 1.1 1.2 9.0 0.0 2.5 3 0 0 3 3 3 0 N-terminal of Junction-mediating and WASP homolog-associated DUF285 PF03382.14 GAX28568.1 - 2.8e-109 359.6 60.1 2.6e-31 107.9 7.6 5.2 2 2 3 5 5 5 5 Mycoplasma protein of unknown function, DUF285 CagS PF16707.5 GAX28570.1 - 0.017 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori DUF4080 PF13311.6 GAX28570.1 - 0.056 13.6 0.0 0.059 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) SAP PF02037.27 GAX28571.1 - 0.00041 20.0 0.3 0.00095 18.9 0.3 1.6 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 GAX28571.1 - 0.011 15.1 0.2 0.023 14.1 0.2 1.5 1 0 0 1 1 1 0 LETM1-like protein SlyX PF04102.12 GAX28571.1 - 3.1 8.5 11.7 2.7 8.7 0.8 4.0 3 1 0 3 3 3 0 SlyX Endotoxin_C2 PF18449.1 GAX28571.1 - 6.4 7.2 6.4 3.8 7.9 0.8 2.7 2 0 0 2 2 2 0 Delta endotoxin TMF_DNA_bd PF12329.8 GAX28571.1 - 8.5 6.5 15.5 2.4 8.2 0.1 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Asn_synthase PF00733.21 GAX28572.1 - 1.8e-88 297.6 0.1 3.1e-54 185.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GAX28572.1 - 1.7e-37 128.1 0.0 2.7e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAX28572.1 - 5.3e-29 101.1 0.0 8.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAX28572.1 - 3e-11 43.2 0.0 6.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 GAX28572.1 - 0.0031 16.7 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD synthase UbiA PF01040.18 GAX28573.1 - 6.5e-28 97.7 12.4 4.4e-26 91.7 11.5 2.4 1 1 1 2 2 2 1 UbiA prenyltransferase family DUF2098 PF09871.9 GAX28574.1 - 0.48 10.8 3.6 0.25 11.7 0.7 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) MCPVI PF02993.14 GAX28574.1 - 1.7 8.4 5.4 0.36 10.6 1.7 1.7 2 0 0 2 2 2 0 Minor capsid protein VI SPT16 PF08644.11 GAX28575.1 - 2.6e-51 173.8 0.1 2.6e-51 173.8 0.1 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 GAX28575.1 - 2.2e-37 128.4 0.0 6e-37 126.9 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 GAX28575.1 - 8.7e-29 100.7 0.0 1.9e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 GAX28575.1 - 4e-13 49.6 0.1 8.6e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like BP28CT PF08146.12 GAX28575.1 - 0.12 12.2 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 BP28CT (NUC211) domain NPR2 PF06218.11 GAX28576.1 - 8.2e-49 166.5 0.0 2.5e-46 158.3 0.0 2.9 1 1 0 1 1 1 1 Nitrogen permease regulator 2 AAA_26 PF13500.6 GAX28577.1 - 7.5e-36 123.8 0.0 9.9e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAX28577.1 - 1.2e-06 28.6 0.0 3e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 GAX28577.1 - 0.0075 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 DRTGG domain AAA_31 PF13614.6 GAX28577.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 GAX28577.1 - 0.11 11.6 0.2 0.49 9.5 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase CBP_BcsR PF10945.8 GAX28577.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Vps51 PF08700.11 GAX28578.1 - 0.00018 21.5 0.2 0.00066 19.7 0.2 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Laminin_II PF06009.12 GAX28578.1 - 0.0077 16.3 3.4 1.3 9.0 0.5 3.0 2 0 0 2 2 2 2 Laminin Domain II EF-hand_8 PF13833.6 GAX28578.1 - 0.021 14.7 0.1 0.072 13.0 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 GAX28578.1 - 0.036 13.6 0.3 0.15 11.7 0.3 2.2 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 GAX28578.1 - 0.11 12.5 0.2 0.49 10.5 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain Astro_capsid_p PF12226.8 GAX28579.1 - 0.17 11.0 17.2 0.34 10.0 17.2 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ER_lumen_recept PF00810.18 GAX28580.1 - 1.7e-33 116.5 2.3 3.4e-33 115.5 2.3 1.5 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 GAX28580.1 - 0.068 13.0 5.0 0.37 10.6 0.1 3.4 3 0 0 3 3 3 0 PQ loop repeat TB2_DP1_HVA22 PF03134.19 GAX28581.1 - 1.1e-29 102.2 7.4 1.6e-29 101.7 7.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 GAX28581.1 - 0.071 13.3 5.1 2.7 8.3 2.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Halogen_Hydrol PF10112.9 GAX28581.1 - 0.97 9.4 4.0 0.28 11.2 0.8 1.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RPA_C PF08784.11 GAX28582.1 - 8.2e-08 32.9 0.6 3.1e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 GAX28582.1 - 0.00028 20.8 0.1 0.00046 20.1 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2666 PF10869.8 GAX28582.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF4817 PF16087.5 GAX28582.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) PCI PF01399.27 GAX28583.1 - 8e-23 81.0 0.5 2.2e-22 79.5 0.5 1.8 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 GAX28583.1 - 0.049 13.6 0.4 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family TPR_12 PF13424.6 GAX28583.1 - 0.094 13.0 0.1 0.78 10.1 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Arm PF00514.23 GAX28584.1 - 5.8e-42 140.5 22.2 3.2e-10 39.7 0.0 8.5 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAX28584.1 - 2.3e-13 50.3 0.7 1.6e-06 28.4 0.0 5.1 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 GAX28584.1 - 4.9e-11 41.9 2.6 0.52 10.7 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 GAX28584.1 - 1.4e-07 31.9 8.5 0.071 13.6 0.0 7.2 6 2 3 9 9 9 3 HEAT-like repeat Arm_3 PF16186.5 GAX28584.1 - 0.0005 19.6 0.0 0.083 12.5 0.0 2.8 2 0 0 2 2 2 1 Atypical Arm repeat DDHD PF02862.17 GAX28584.1 - 0.4 10.8 9.6 1.2 9.3 6.2 2.5 2 0 0 2 2 2 0 DDHD domain BSP_II PF05432.11 GAX28584.1 - 0.87 9.2 16.2 2.5 7.7 16.2 1.7 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) VHL PF01847.16 GAX28585.1 - 0.00067 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 VHL beta domain Flavoprotein PF02441.19 GAX28587.1 - 1.3e-38 132.3 0.0 2.1e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein LRR_6 PF13516.6 GAX28588.1 - 8.6e-29 97.1 13.0 0.00016 21.4 0.0 10.1 10 0 0 10 10 10 7 Leucine Rich repeat LRR_4 PF12799.7 GAX28588.1 - 1.6e-06 28.3 6.5 1 9.9 0.1 6.5 5 3 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX28588.1 - 0.00075 19.2 14.7 0.55 10.0 0.1 6.4 4 2 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 GAX28588.1 - 0.016 15.7 8.5 1.2e+02 3.9 0.0 7.1 8 1 0 8 8 8 0 Leucine Rich Repeat SAM_PNT PF02198.16 GAX28588.1 - 0.14 12.1 0.1 0.98 9.4 0.0 2.2 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain UDPGP PF01704.18 GAX28589.1 - 3.3e-55 187.4 0.0 4.3e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 GAX28589.1 - 0.003 17.9 0.0 0.0057 17.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NARP1 PF12569.8 GAX28590.1 - 1.1e-131 440.3 5.6 1.1e-131 440.3 5.6 2.6 2 2 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 GAX28590.1 - 1e-15 57.9 2.1 0.0001 22.7 0.1 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28590.1 - 7.5e-15 53.8 17.6 1.8e-06 27.6 0.2 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAX28590.1 - 2.9e-14 52.6 4.5 0.012 16.4 0.0 7.5 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28590.1 - 9.1e-12 44.3 10.9 4.9e-06 26.1 0.3 7.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX28590.1 - 1.4e-10 40.5 2.8 1.3e-05 25.0 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX28590.1 - 2.7e-09 37.5 1.9 0.12 13.0 0.0 6.6 7 2 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX28590.1 - 7.1e-08 32.6 4.9 0.074 13.3 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX28590.1 - 8.2e-08 32.1 4.2 0.0017 18.6 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX28590.1 - 1e-07 31.5 2.3 5.3e-06 26.0 0.5 4.0 3 1 0 3 3 3 1 TPR repeat Fis1_TPR_C PF14853.6 GAX28590.1 - 4.9e-06 26.5 8.5 0.05 13.7 0.3 5.6 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 GAX28590.1 - 3.2e-05 24.0 0.1 0.48 10.6 0.2 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX28590.1 - 0.00019 21.6 9.7 0.49 10.7 0.7 5.7 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAX28590.1 - 0.00062 19.6 2.7 0.01 15.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX28590.1 - 0.00069 20.1 16.6 3.7 8.4 0.1 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat PIN_6 PF17146.4 GAX28590.1 - 0.031 14.8 0.1 0.58 10.7 0.0 2.8 2 0 0 2 2 2 0 PIN domain of ribonuclease NADH5_C PF06455.11 GAX28590.1 - 0.1 12.2 0.0 0.96 9.0 0.0 2.1 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus TPR_15 PF13429.6 GAX28590.1 - 0.12 11.5 2.7 0.3 10.2 0.1 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAX28590.1 - 1 9.4 9.3 5.4 7.1 0.1 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 GAX28590.1 - 2.6 8.2 5.9 2.5 8.2 0.3 3.8 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain ANTH PF07651.16 GAX28591.1 - 4e-08 32.6 0.0 6.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 GAX28591.1 - 0.02 14.9 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 ENTH domain DUF4746 PF15928.5 GAX28591.1 - 0.34 10.3 17.2 0.17 11.3 9.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) TP_methylase PF00590.20 GAX28592.1 - 8.1e-26 91.3 0.1 1.7e-25 90.2 0.1 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UFD1 PF03152.14 GAX28593.1 - 1.2e-20 73.7 0.0 2.6e-11 43.3 0.0 3.1 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 GAX28593.1 - 8.6e-14 51.5 0.1 1.8e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 UBX domain DUF4407 PF14362.6 GAX28593.1 - 0.47 9.8 4.6 0.76 9.1 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DHHC PF01529.20 GAX28594.1 - 2.4e-14 53.6 0.1 2.4e-14 53.6 0.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase zinc_ribbon_2 PF13240.6 GAX28594.1 - 0.018 14.8 0.5 0.095 12.5 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF3464 PF11947.8 GAX28594.1 - 0.071 12.9 1.2 0.17 11.7 1.2 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SPX PF03105.19 GAX28595.1 - 1.1e-14 55.2 19.2 3e-09 37.3 0.9 3.6 2 1 2 4 4 4 3 SPX domain Baculo_p24 PF05073.12 GAX28595.1 - 0.045 13.5 0.1 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 Baculovirus P24 capsid protein KCNQ2_u3 PF16642.5 GAX28595.1 - 0.32 12.0 1.7 0.5 11.4 0.1 2.1 2 1 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 WD40 PF00400.32 GAX28596.1 - 2e-14 53.8 3.9 1.1e-06 29.2 0.0 5.0 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28596.1 - 2.6e-09 37.3 0.0 0.079 13.3 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAX28596.1 - 0.00051 20.5 0.1 0.26 11.9 0.0 3.7 3 1 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 GAX28596.1 - 0.036 13.6 0.1 0.64 9.5 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain SpoU_methylase PF00588.19 GAX28597.1 - 2.5e-06 27.7 0.0 7.3e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family Bac_globin PF01152.21 GAX28598.1 - 2.8e-07 30.7 0.0 4.9e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Bacterial-like globin DUF4420 PF14390.6 GAX28598.1 - 0.0032 16.8 0.0 0.051 12.8 0.0 2.1 1 1 1 2 2 2 1 Putative PD-(D/E)XK family member, (DUF4420) PPR_2 PF13041.6 GAX28599.1 - 1.8e-08 34.4 0.0 1.9 8.7 0.0 6.0 5 1 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 GAX28599.1 - 3.3e-07 30.3 0.0 0.02 15.0 0.0 3.6 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX28599.1 - 6.8e-07 28.9 0.6 0.021 14.2 0.1 3.4 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP DUF1643 PF07799.12 GAX28599.1 - 0.16 12.1 0.6 0.91 9.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1643) FAD_binding_3 PF01494.19 GAX28600.1 - 1.5e-38 133.0 0.1 2.6e-38 132.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 GAX28600.1 - 2.4e-07 30.1 0.0 2.3e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase zf-C3H1 PF10650.9 GAX28600.1 - 3.7e-06 26.5 1.0 6.4e-06 25.8 1.0 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain LRR_8 PF13855.6 GAX28600.1 - 2.3e-05 24.0 2.4 0.0021 17.8 0.9 2.7 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 GAX28600.1 - 0.0026 18.1 2.2 3.7 8.1 1.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Pro_isomerase PF00160.21 GAX28601.1 - 5.6e-40 137.2 0.0 8.1e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD KfrB PF18790.1 GAX28603.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 KfrB protein Sec20 PF03908.13 GAX28605.1 - 0.0005 19.9 0.0 0.00082 19.2 0.0 1.4 1 1 0 1 1 1 1 Sec20 Hira PF07569.11 GAX28608.1 - 0.00069 19.4 0.0 1.7 8.3 0.0 3.1 2 1 1 3 3 3 2 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 GAX28608.1 - 0.00076 19.7 0.0 1.3 9.4 0.0 3.9 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAX28608.1 - 0.00082 18.8 0.0 0.16 11.2 0.0 2.2 1 1 0 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 GAX28608.1 - 0.014 15.4 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 GAX28608.1 - 0.02 15.8 6.4 0.23 12.4 0.1 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Nup160 PF11715.8 GAX28608.1 - 0.059 12.0 0.1 4.3 5.9 0.0 2.8 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 GAX28608.1 - 0.12 10.9 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Flavokinase PF01687.17 GAX28609.1 - 2.2e-26 92.4 0.0 2.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PSII_BNR PF14870.6 GAX28610.1 - 9.1e-126 419.2 2.0 1.1e-125 418.9 2.0 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 GAX28610.1 - 3e-09 35.5 5.0 0.66 10.2 0.0 5.6 5 0 0 5 5 5 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 GAX28610.1 - 1.2e-06 27.6 0.1 0.0065 15.3 0.0 3.2 2 1 0 3 3 3 2 Sortilin, neurotensin receptor 3, DUF4185 PF13810.6 GAX28610.1 - 0.026 13.8 1.6 1.4 8.1 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4185) Fez1 PF06818.15 GAX28611.1 - 4e-05 24.2 10.5 4e-05 24.2 10.5 4.2 2 1 1 4 4 4 3 Fez1 OmpH PF03938.14 GAX28611.1 - 0.0034 17.7 3.7 0.0034 17.7 3.7 4.8 3 2 1 4 4 4 1 Outer membrane protein (OmpH-like) DUF4837 PF16125.5 GAX28611.1 - 0.18 10.8 3.4 0.47 9.4 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) UPF0242 PF06785.11 GAX28611.1 - 0.67 10.0 48.6 0.095 12.8 15.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 GAX28611.1 - 1.4 8.3 52.6 0.17 11.3 9.0 3.2 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF4407 PF14362.6 GAX28611.1 - 4.2 6.6 40.9 0.37 10.1 8.4 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Gtr1_RagA PF04670.12 GAX28612.1 - 4.6e-51 173.4 0.0 1.1e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region NifT PF06988.11 GAX28612.1 - 0.00027 20.7 0.0 0.00067 19.4 0.0 1.6 1 0 0 1 1 1 1 NifT/FixU protein AAA_14 PF13173.6 GAX28612.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX28612.1 - 0.14 12.5 0.0 0.37 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain SpecificRecomb PF10136.9 GAX28612.1 - 0.14 10.4 0.6 0.43 8.8 0.1 1.9 2 1 1 3 3 3 0 Site-specific recombinase MMR_HSR1 PF01926.23 GAX28612.1 - 0.16 12.1 0.0 0.86 9.7 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Thioredoxin PF00085.20 GAX28613.1 - 6.3e-16 58.2 0.0 1.6e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 GAX28613.1 - 7.8e-12 45.0 0.0 2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 PUB domain Thioredoxin_8 PF13905.6 GAX28613.1 - 0.00018 21.8 0.0 0.00054 20.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GAX28613.1 - 0.0073 16.5 0.0 0.025 14.8 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX28613.1 - 0.051 14.0 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 GAX28613.1 - 0.15 12.3 0.0 0.79 10.0 0.0 2.3 1 0 0 1 1 1 0 Glutaredoxin Glyco_trans_1_2 PF13524.6 GAX28614.1 - 6.6e-09 36.1 0.0 1.9e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 FAM209 PF15206.6 GAX28614.1 - 0.033 14.0 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 FAM209 family AbiEi_1 PF09407.10 GAX28614.1 - 0.05 13.9 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain DnaJ PF00226.31 GAX28615.1 - 2.1e-10 40.5 0.1 4.7e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 GAX28616.1 - 1.1e-48 166.0 0.0 1.5e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX28616.1 - 2e-23 83.0 0.0 3.1e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L31e PF01198.19 GAX28617.1 - 3.2e-42 142.7 1.1 3.9e-42 142.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DHquinase_I PF01487.15 GAX28618.1 - 1.5e-24 87.5 0.0 6.6e-22 78.9 0.0 2.8 2 1 0 2 2 2 2 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 GAX28618.1 - 1.2e-22 79.9 0.6 4.8e-22 78.0 0.1 2.2 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 GAX28618.1 - 1.7e-11 43.6 0.5 4e-11 42.5 0.5 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain PALP PF00291.25 GAX28618.1 - 0.00048 19.6 0.0 0.026 14.0 0.0 2.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Shikimate_DH PF01488.20 GAX28618.1 - 0.00076 19.6 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAX28618.1 - 0.073 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAX28618.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3506 PF12014.8 GAX28620.1 - 1.4e-12 47.8 0.1 3.2e-07 30.4 0.0 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF3506) DUF4398 PF14346.6 GAX28620.1 - 0.19 12.4 6.2 0.39 11.4 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF3506 PF12014.8 GAX28621.1 - 1.4e-13 51.1 0.0 1.4e-10 41.3 0.0 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) CBM_19 PF03427.13 GAX28621.1 - 0.16 12.0 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) DEAD PF00270.29 GAX28622.1 - 8.1e-46 156.0 0.0 1.6e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX28622.1 - 2.7e-29 101.7 0.3 2.4e-28 98.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28622.1 - 0.0003 20.8 0.0 0.0003 20.8 0.0 3.3 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Phosphodiest PF01663.22 GAX28623.1 - 4.2e-12 46.3 0.2 6.8e-12 45.6 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 GAX28623.1 - 3.2e-06 26.7 0.6 5.1e-06 26.0 0.6 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 GAX28623.1 - 0.017 14.6 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Sulfatase LTV PF04180.14 GAX28624.1 - 4.8e-10 39.7 10.7 2.2e-05 24.4 0.0 3.7 3 1 0 3 3 3 2 Low temperature viability protein TPR_8 PF13181.6 GAX28625.1 - 2.9 8.3 5.3 0.88 10.0 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 GAX28626.1 - 1.5e-24 86.6 40.1 1.5e-24 86.6 40.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily C2 PF00168.30 GAX28627.1 - 3.2e-29 101.3 0.0 1.3e-14 54.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain DUF2229 PF09989.9 GAX28627.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Caudo_TAP PF02413.17 GAX28627.1 - 4.4 7.5 6.6 0.28 11.3 0.5 2.1 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK COPIIcoated_ERV PF07970.12 GAX28629.1 - 6.3e-24 85.1 0.3 1.3e-23 84.0 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAX28629.1 - 5.1e-14 52.4 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) C2 PF00168.30 GAX28630.1 - 2e-12 47.3 0.0 5.3e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain PRT_C PF08372.10 GAX28630.1 - 0.0069 16.2 0.2 0.0069 16.2 0.2 1.9 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal AAA_3 PF07726.11 GAX28630.1 - 0.01 15.7 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LSM PF01423.22 GAX28631.1 - 6.8e-22 76.9 0.2 8.5e-22 76.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain HydF_dimer PF18128.1 GAX28631.1 - 0.13 12.4 0.2 0.65 10.1 0.0 1.9 2 0 0 2 2 2 0 Hydrogen maturase F dimerization domain NTPase_I-T PF01931.18 GAX28632.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 PIG-L PF02585.17 GAX28632.1 - 0.21 12.2 0.0 0.62 10.7 0.0 1.8 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase ATG16 PF08614.11 GAX28633.1 - 0.0033 17.7 20.7 0.0033 17.7 20.7 4.9 1 1 4 5 5 5 2 Autophagy protein 16 (ATG16) ABC_tran PF00005.27 GAX28634.1 - 3e-43 147.6 0.0 2.7e-21 76.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 GAX28634.1 - 2.5e-40 138.2 62.4 5.1e-29 101.2 21.4 3.1 3 0 0 3 3 3 2 ABC-2 type transporter AAA_29 PF13555.6 GAX28634.1 - 1.5e-08 34.3 1.0 0.00052 19.7 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAX28634.1 - 1.2e-06 29.2 0.0 0.0048 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAX28634.1 - 8.2e-06 25.8 0.2 1.2 8.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX28634.1 - 1.4e-05 25.5 0.0 0.027 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 GAX28634.1 - 1.6e-05 24.9 0.0 0.0038 17.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 GAX28634.1 - 0.00013 22.2 0.0 0.63 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAX28634.1 - 0.00015 21.7 0.0 0.031 14.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 GAX28634.1 - 0.00061 19.6 0.1 0.32 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAX28634.1 - 0.0021 18.5 0.3 0.86 10.0 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 GAX28634.1 - 0.0024 17.3 0.0 0.49 9.7 0.0 2.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_33 PF13671.6 GAX28634.1 - 0.0036 17.5 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 GAX28634.1 - 0.0041 17.0 0.0 0.3 11.0 0.0 2.8 3 0 0 3 3 2 1 NTPase NACHT PF05729.12 GAX28634.1 - 0.0072 16.3 0.3 1.7 8.5 0.1 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 GAX28634.1 - 0.012 15.2 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 GAX28634.1 - 0.027 14.5 0.2 4.3 7.4 0.1 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 GAX28634.1 - 0.028 14.4 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 GAX28634.1 - 0.036 13.8 0.3 7.4 6.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 GAX28634.1 - 0.037 13.4 0.4 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAX28634.1 - 0.047 14.2 0.0 6.4 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 GAX28634.1 - 0.055 12.3 0.1 0.7 8.6 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_19 PF13245.6 GAX28634.1 - 0.076 13.4 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAX28634.1 - 0.076 12.6 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAX28634.1 - 0.15 11.4 0.1 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin V_ATPase_I PF01496.19 GAX28635.1 - 6e-270 897.7 0.1 6.2e-267 887.7 0.1 2.3 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1151 PF06625.11 GAX28635.1 - 0.081 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DR2241 PF18069.1 GAX28635.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 DR2241 stabilising domain Secretin PF00263.21 GAX28636.1 - 0.034 13.8 1.5 0.059 13.0 0.0 2.2 2 1 0 2 2 2 0 Bacterial type II and III secretion system protein S1-P1_nuclease PF02265.16 GAX28638.1 - 5.5e-60 203.3 0.3 7.6e-60 202.8 0.3 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease Stc1 PF12898.7 GAX28639.1 - 7.9e-06 26.3 2.1 2e-05 25.1 2.1 1.8 1 0 0 1 1 1 1 Stc1 domain IBV_3C PF03620.13 GAX28639.1 - 0.25 11.8 0.0 0.54 10.8 0.0 1.5 1 0 0 1 1 1 0 IBV 3C protein LCM PF04072.14 GAX28641.1 - 8.7e-27 94.3 0.0 1.2e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Chloroa_b-bind PF00504.21 GAX28645.1 - 3.5e-25 89.4 1.2 4.8e-25 89.0 1.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein FA_desaturase PF00487.24 GAX28648.1 - 1.5e-11 44.7 24.5 2.6e-11 43.9 24.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase zf-MYND PF01753.18 GAX28650.1 - 7.5e-09 35.5 15.5 7.5e-09 35.5 15.5 3.6 3 1 0 3 3 2 1 MYND finger zf-C3HC4 PF00097.25 GAX28650.1 - 2.4e-05 24.1 4.4 2.4e-05 24.1 4.4 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX28650.1 - 8e-05 22.4 3.1 8e-05 22.4 3.1 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX28650.1 - 0.00034 20.9 4.7 0.00034 20.9 4.7 2.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAX28650.1 - 0.00051 20.0 3.0 0.00051 20.0 3.0 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-C6H2 PF15801.5 GAX28650.1 - 0.0036 17.6 12.1 0.0038 17.5 8.9 2.4 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-RING_5 PF14634.6 GAX28650.1 - 0.011 15.7 4.5 0.011 15.7 4.5 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAX28650.1 - 0.015 15.5 3.0 0.015 15.5 3.0 2.4 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF1844 PF08899.11 GAX28650.1 - 0.046 14.0 0.1 0.44 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) zf-ANAPC11 PF12861.7 GAX28650.1 - 0.07 13.2 0.4 0.07 13.2 0.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAX28650.1 - 2.8 7.8 16.7 0.035 13.9 5.9 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 GAX28650.1 - 6.4 6.7 17.9 0.073 12.9 7.9 2.8 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAX28650.1 - 9.8 6.1 10.9 1.8 8.5 3.8 2.8 2 1 0 2 2 2 0 zf-RING of BARD1-type protein FA_desaturase PF00487.24 GAX28651.1 - 2.7e-11 43.8 19.5 5.3e-11 42.9 19.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase V_ATPase_I PF01496.19 GAX28652.1 - 3.9e-271 901.6 3.0 1.9e-206 687.7 0.0 2.3 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family FlxA PF14282.6 GAX28652.1 - 0.19 11.8 0.7 0.33 11.0 0.7 1.3 1 0 0 1 1 1 0 FlxA-like protein DHR10 PF18595.1 GAX28652.1 - 1.4 9.0 3.6 2.9 8.0 3.6 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain UPF0176_N PF17773.1 GAX28653.1 - 7.5e-12 45.5 0.0 2.3e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAX28653.1 - 1e-10 41.8 9.7 1e-10 41.8 9.7 2.5 3 0 0 3 3 3 1 Rhodanase C-terminal Rhodanese PF00581.20 GAX28653.1 - 3.2e-08 34.0 0.0 5.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain GRIM-19 PF06212.12 GAX28654.1 - 5.3e-32 110.5 0.1 6.3e-32 110.3 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein TruD PF01142.18 GAX28655.1 - 4.7e-60 203.6 0.1 9.5e-57 192.7 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) PDT PF00800.18 GAX28657.1 - 3.7e-51 173.5 0.0 7.8e-51 172.5 0.0 1.6 1 0 0 1 1 1 1 Prephenate dehydratase PDH PF02153.17 GAX28657.1 - 1.6e-12 47.0 0.0 2.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 GAX28657.1 - 1.7e-12 47.7 0.0 5.2e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAX28657.1 - 8.1e-07 28.6 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAX28657.1 - 2.7e-05 24.4 0.0 5.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 GAX28657.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 GAX28657.1 - 0.0017 18.0 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 GAX28657.1 - 0.0028 17.5 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 Rossmann-like domain GFO_IDH_MocA PF01408.22 GAX28657.1 - 0.11 13.3 0.0 1.3 9.9 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 GAX28657.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Metallophos_2 PF12850.7 GAX28658.1 - 2.7e-09 37.4 1.3 0.00038 20.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GAX28658.1 - 9.5e-08 32.8 5.2 1.8e-06 28.6 5.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DFRP_C PF16543.5 GAX28659.1 - 0.94 10.0 6.9 0.26 11.8 2.7 2.4 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 p450 PF00067.22 GAX28661.1 - 2.9e-80 270.3 0.0 6.3e-80 269.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 PI-PLC-X PF00388.19 GAX28662.1 - 3.6e-20 72.0 0.0 2.4e-19 69.4 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAX28662.1 - 2.5e-18 66.5 0.2 2.8e-17 63.1 0.0 2.9 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 GAX28662.1 - 0.0013 19.2 0.1 0.0056 17.1 0.1 2.2 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 GAX28662.1 - 0.016 15.5 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 C2 domain DnaG_DnaB_bind PF08278.11 GAX28663.1 - 0.021 15.4 1.0 0.071 13.7 1.0 1.9 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Peptidase_M50 PF02163.22 GAX28663.1 - 1.3 8.2 4.2 5.9 6.1 0.1 3.0 2 1 0 3 3 3 0 Peptidase family M50 T7SS_ESX1_EccB PF05108.13 GAX28664.1 - 0.019 13.7 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B DUF3655 PF12379.8 GAX28664.1 - 0.029 14.6 1.9 3 8.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3655) PBP1_TM PF14812.6 GAX28664.1 - 3 8.3 7.4 40 4.7 7.4 2.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M50 PF02163.22 GAX28665.1 - 2.1e-05 23.9 5.1 0.0054 16.0 0.9 2.4 2 0 0 2 2 2 2 Peptidase family M50 SlyX PF04102.12 GAX28665.1 - 0.051 14.2 1.7 0.12 13.1 1.7 1.6 1 0 0 1 1 1 0 SlyX DUF4349 PF14257.6 GAX28665.1 - 0.068 12.6 3.3 0.15 11.4 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Bap31_Bap29_C PF18035.1 GAX28665.1 - 0.24 11.4 3.8 0.69 10.0 3.8 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain TMEM247 PF15444.6 GAX28665.1 - 0.52 10.3 3.2 0.93 9.5 3.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 DUF1043 PF06295.12 GAX28665.1 - 0.92 9.5 3.8 1.6 8.8 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) AAA_23 PF13476.6 GAX28665.1 - 1.3 9.5 10.5 0.47 10.9 7.4 1.8 2 0 0 2 2 2 0 AAA domain WDCP PF15390.6 GAX28665.1 - 7.5 4.8 8.9 11 4.3 8.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PFU PF09070.11 GAX28666.1 - 2.7e-26 92.1 0.2 5.5e-26 91.1 0.2 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 GAX28666.1 - 1.2e-23 83.8 5.8 2.2e-23 82.9 5.8 1.4 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 GAX28666.1 - 9.5e-22 76.9 9.7 5.3e-09 36.6 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAX28666.1 - 0.042 12.8 0.9 5.2 5.9 0.0 3.0 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2695 PF10905.8 GAX28666.1 - 0.16 12.2 0.2 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) SET PF00856.28 GAX28667.1 - 1.7e-05 25.3 0.0 0.0048 17.3 0.0 2.2 1 1 1 2 2 2 2 SET domain Guanylate_cyc PF00211.20 GAX28669.1 - 3.5e-48 163.7 0.0 6.9e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX28669.1 - 4.9e-33 114.8 0.2 1.3e-32 113.5 0.2 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GET2 PF08690.10 GAX28669.1 - 0.07 12.8 0.6 0.22 11.2 0.1 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 DAO PF01266.24 GAX28670.1 - 0.0085 15.7 0.5 0.98 8.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAX28670.1 - 0.029 13.4 0.1 0.57 9.2 0.1 2.3 1 1 0 1 1 1 0 Lycopene cyclase protein FA_hydroxylase PF04116.13 GAX28671.1 - 3.4e-18 66.3 19.5 3.4e-18 66.3 19.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Wax2_C PF12076.8 GAX28671.1 - 2e-05 24.4 0.0 0.0001 22.0 0.0 2.1 2 0 0 2 2 2 1 WAX2 C-terminal domain NAD_binding_10 PF13460.6 GAX28671.1 - 0.1 12.5 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding TauE PF01925.19 GAX28672.1 - 7.9e-20 71.5 20.1 5.7e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE TPR_1 PF00515.28 GAX28673.1 - 7.5e-05 22.4 0.3 0.0003 20.5 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28673.1 - 0.00071 19.5 0.0 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX28673.1 - 0.0025 18.1 0.8 0.0047 17.2 0.3 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 GAX28673.1 - 0.0084 16.2 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 GAX28673.1 - 0.05 13.5 0.3 0.099 12.5 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M43 PF05572.13 GAX28675.1 - 2.4e-10 40.5 0.4 6.3e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 GAX28675.1 - 0.002 18.6 0.0 0.0074 16.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX28675.1 - 0.0033 17.6 0.6 0.011 15.9 0.6 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 GAX28675.1 - 0.012 15.8 0.6 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 GAX28675.1 - 0.025 13.6 0.4 0.042 12.8 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 GAX28675.1 - 0.035 13.3 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 GAX28675.1 - 0.039 13.6 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 GAX28675.1 - 0.063 11.9 0.6 0.096 11.3 0.6 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.24 GAX28675.1 - 0.18 11.6 0.3 0.39 10.5 0.3 1.5 1 0 0 1 1 1 0 Matrixin HSF_DNA-bind PF00447.17 GAX28679.1 - 5.5e-18 65.4 0.1 8.9e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.25 GAX28680.1 - 5.2e-54 183.4 0.0 9.4e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX28680.1 - 2.5e-20 72.8 0.1 1.4e-16 60.6 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAX28680.1 - 0.0096 15.3 0.1 0.0096 15.3 0.1 2.2 3 0 0 3 3 3 1 Kinase-like IATP PF04568.12 GAX28681.1 - 0.00034 21.0 0.5 0.00044 20.6 0.5 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP EIIBC-GUT_N PF03612.14 GAX28681.1 - 0.03 14.0 1.4 0.035 13.8 1.4 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus LRR_6 PF13516.6 GAX28681.1 - 0.077 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Leucine Rich repeat MFS_1 PF07690.16 GAX28682.1 - 2.5e-31 108.9 29.9 2.5e-31 108.9 29.9 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAX28682.1 - 1.1e-07 31.1 22.7 1.4e-06 27.4 22.7 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAX28682.1 - 3.4e-05 22.9 25.2 7.4e-05 21.8 10.9 3.3 2 2 2 4 4 4 2 MFS_1 like family OATP PF03137.20 GAX28682.1 - 0.0026 16.1 10.0 0.016 13.5 9.9 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family YrhC PF14143.6 GAX28682.1 - 0.8 9.8 3.7 0.73 10.0 0.6 2.6 2 0 0 2 2 2 0 YrhC-like protein zf-CXXC PF02008.20 GAX28683.1 - 8.8e-06 25.7 5.6 1.9e-05 24.6 5.6 1.6 1 0 0 1 1 1 1 CXXC zinc finger domain Lipocalin_5 PF13924.6 GAX28683.1 - 0.057 13.2 0.0 2.1 8.1 0.0 2.9 2 0 0 2 2 2 0 Lipocalin-like domain PhoR PF11808.8 GAX28684.1 - 0.077 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR AMP-binding PF00501.28 GAX28685.1 - 5.9e-85 285.4 0.1 9.6e-85 284.7 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_1_2 PF00155.21 GAX28686.1 - 1.2e-58 199.0 0.0 1.4e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAX28686.1 - 4.7e-06 25.7 0.0 7.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 GAX28686.1 - 0.00039 19.5 0.0 0.00059 18.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 GAX28686.1 - 0.00079 18.2 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAX28686.1 - 0.0016 17.8 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 2 Beta-eliminating lyase Alliinase_C PF04864.13 GAX28686.1 - 0.006 15.5 0.0 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 Allinase Suf PF05843.14 GAX28687.1 - 4.8e-18 66.2 1.8 6.2e-14 52.7 0.0 3.5 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) DUF4614 PF15391.6 GAX28687.1 - 0.096 12.7 2.3 0.34 10.9 2.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) HSF_DNA-bind PF00447.17 GAX28688.1 - 4.5e-16 59.3 0.1 7.5e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Lipase_3 PF01764.25 GAX28689.1 - 9.2e-17 61.2 0.0 1.6e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Exotox-A_target PF09102.10 GAX28689.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Exotoxin A, targeting YjbH PF06082.11 GAX28690.1 - 0.11 11.3 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH WD40 PF00400.32 GAX28691.1 - 7.9e-18 64.5 3.3 0.00011 23.0 0.2 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28691.1 - 1.5e-08 34.8 0.3 0.026 14.8 0.0 4.7 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 GAX28691.1 - 1.7e-06 27.6 0.6 3.6e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 LisH-like dimerisation domain LisH PF08513.11 GAX28691.1 - 0.0014 18.5 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 LisH PALB2_WD40 PF16756.5 GAX28691.1 - 0.0038 16.2 2.6 0.021 13.8 0.2 2.9 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 GAX28691.1 - 0.0059 15.6 0.4 0.25 10.3 0.0 3.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CNH PF00780.22 GAX28691.1 - 0.007 16.0 0.3 0.02 14.5 0.2 1.7 1 1 1 2 2 2 1 CNH domain DUF1513 PF07433.11 GAX28691.1 - 0.036 13.1 0.1 0.41 9.7 0.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) Carb_anhydrase PF00194.21 GAX28692.1 - 1.4e-16 60.8 1.8 3.1e-07 30.2 0.9 3.1 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 GAX28693.1 - 1.3e-15 57.7 2.8 1.7e-07 31.0 0.0 3.3 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase SBP_bac_5 PF00496.22 GAX28694.1 - 2.1e-43 148.8 0.0 3.4e-37 128.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle Cas1_AcylT PF07779.12 GAX28695.1 - 1.6e-82 278.0 30.4 2.2e-82 277.5 30.4 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 GAX28695.1 - 2.2e-05 24.3 1.7 0.00014 21.7 0.0 2.7 2 1 1 3 3 3 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PriCT_2 PF08707.11 GAX28695.1 - 0.046 14.1 3.9 2.2 8.7 0.1 3.1 3 0 0 3 3 3 0 Primase C terminal 2 (PriCT-2) Lipase_GDSL_2 PF13472.6 GAX28695.1 - 0.11 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Phage_holin_2_3 PF16080.5 GAX28695.1 - 2.3 8.1 5.4 42 4.0 2.0 3.0 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Vps51 PF08700.11 GAX28696.1 - 2e-17 63.1 1.4 2e-17 63.1 1.4 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 GAX28696.1 - 4.1e-09 35.6 7.3 8.5e-09 34.5 7.3 1.5 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 GAX28696.1 - 8.9e-09 35.4 0.0 2.3e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.9 GAX28696.1 - 0.00013 22.1 2.3 0.00013 22.1 2.3 3.0 3 0 0 3 3 3 1 Golgi transport complex subunit 5 COG2 PF06148.11 GAX28696.1 - 0.0012 19.0 0.7 0.0012 19.0 0.7 2.4 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 GAX28696.1 - 0.0012 18.2 3.4 0.0012 18.2 3.4 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex TetR_C_36 PF18598.1 GAX28696.1 - 0.002 18.1 0.3 0.0091 15.9 0.3 2.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain ArAE_1_C PF11728.8 GAX28696.1 - 0.011 15.8 1.5 6.4 6.7 0.0 3.6 3 0 0 3 3 3 0 Putative aromatic acid exporter C-terminal domain Endotoxin_N PF03945.14 GAX28696.1 - 0.15 11.8 0.7 0.37 10.5 0.4 1.8 2 1 0 2 2 2 0 delta endotoxin, N-terminal domain V-SNARE PF05008.15 GAX28696.1 - 0.16 12.4 3.2 23 5.4 0.0 3.7 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus AAA PF00004.29 GAX28698.1 - 6.1e-16 59.0 0.0 9.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 GAX28698.1 - 9e-14 51.7 0.0 2.2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAX28698.1 - 1.8e-11 44.1 0.0 2e-09 37.4 0.0 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 GAX28698.1 - 2.2e-07 31.0 0.0 4.9e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 GAX28698.1 - 1.1e-05 25.3 0.0 2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAX28698.1 - 2.5e-05 24.6 1.1 0.26 11.6 0.1 2.7 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 GAX28698.1 - 2.7e-05 24.6 0.0 9e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAX28698.1 - 7.1e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 GAX28698.1 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 GAX28698.1 - 0.00015 21.7 0.1 0.0003 20.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GAX28698.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAX28698.1 - 0.00022 21.0 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAX28698.1 - 0.00057 19.7 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAX28698.1 - 0.0007 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GAX28698.1 - 0.00075 19.3 0.3 0.011 15.5 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 GAX28698.1 - 0.00079 20.0 0.0 0.026 15.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 GAX28698.1 - 0.00085 19.7 0.7 0.02 15.2 0.2 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GAX28698.1 - 0.0041 16.3 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 GAX28698.1 - 0.006 16.6 0.0 0.64 10.0 0.0 2.2 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit DNA_pol3_delta PF06144.13 GAX28698.1 - 0.0072 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_7 PF12775.7 GAX28698.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 GAX28698.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain TIP49 PF06068.13 GAX28698.1 - 0.062 12.5 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 GAX28698.1 - 0.063 13.2 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 GAX28698.1 - 0.11 11.9 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 GAX28698.1 - 0.12 11.8 0.2 0.42 10.0 0.1 1.8 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 GAX28698.1 - 0.14 11.6 0.1 1.1 8.6 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 GAX28698.1 - 0.16 11.7 0.2 0.34 10.7 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 GAX28699.1 - 2.4e-19 69.3 15.5 0.00014 22.6 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28699.1 - 7.1e-14 51.9 0.5 0.0002 21.6 0.3 4.6 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX28699.1 - 1.9e-05 24.6 0.0 0.57 10.0 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAX28699.1 - 0.0086 15.1 0.0 0.072 12.0 0.0 2.1 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PLAC8 PF04749.17 GAX28700.1 - 3.5e-14 53.6 6.0 7.2e-14 52.6 6.0 1.5 1 1 0 1 1 1 1 PLAC8 family Renin_r PF07850.14 GAX28700.1 - 0.088 13.4 0.1 0.15 12.7 0.1 1.3 1 0 0 1 1 1 0 Renin receptor-like protein DUF2793 PF10983.8 GAX28700.1 - 0.82 9.6 3.1 0.41 10.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) CTP_transf_like PF01467.26 GAX28702.1 - 0.00035 20.8 0.0 0.0029 17.8 0.0 2.4 1 1 0 1 1 1 1 Cytidylyltransferase-like CinA PF02464.17 GAX28702.1 - 0.023 14.3 0.3 0.039 13.5 0.3 1.3 1 0 0 1 1 1 0 Competence-damaged protein TetR_C_20 PF17925.1 GAX28702.1 - 0.15 12.3 2.4 0.88 9.9 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Aminotran_5 PF00266.19 GAX28703.1 - 2.6e-89 299.8 0.0 3.4e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAX28703.1 - 5.5e-09 35.7 0.0 6.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAX28703.1 - 9.3e-05 21.9 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAX28703.1 - 0.0075 14.8 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Mis12 PF05859.12 GAX28705.1 - 0.11 12.5 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Mis12 protein Arrestin_C PF02752.22 GAX28707.1 - 1.6e-07 31.9 0.0 6.4e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAX28707.1 - 2.7e-05 24.2 0.2 6.2e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAX28707.1 - 0.0074 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Carb_anhydrase PF00194.21 GAX28708.1 - 5e-15 55.7 2.7 7.6e-07 28.9 0.0 3.3 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase CBM_6 PF03422.15 GAX28709.1 - 1.1e-07 32.1 0.5 3e-07 30.8 0.5 1.7 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DEAD PF00270.29 GAX28710.1 - 1.2e-30 106.5 0.2 6e-30 104.3 0.3 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX28710.1 - 5.3e-17 62.2 0.0 4.2e-16 59.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28710.1 - 4.2e-06 26.9 0.0 9.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3638 PF12340.8 GAX28710.1 - 0.012 14.9 0.1 0.036 13.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) CBM_6 PF03422.15 GAX28711.1 - 5.6e-25 88.1 0.1 3.1e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX28711.1 - 5.3e-08 33.0 0.0 0.00061 19.9 0.0 2.4 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX28711.1 - 1.7e-07 31.5 0.1 0.0053 17.0 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) CBM_6 PF03422.15 GAX28712.1 - 7.8e-31 107.0 0.2 1.8e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX28712.1 - 5e-13 49.2 0.3 1.1e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX28712.1 - 1.7e-08 34.8 0.3 0.0037 17.5 0.2 2.2 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) Mod_r PF07200.13 GAX28713.1 - 8.9e-26 90.7 12.0 1.4e-25 90.1 12.0 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 GAX28713.1 - 0.0011 19.3 3.5 0.0027 18.0 3.5 1.7 1 0 0 1 1 1 1 Csm1 N-terminal domain Uso1_p115_C PF04871.13 GAX28713.1 - 0.0012 19.3 3.3 0.0023 18.3 3.3 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Rab5-bind PF09311.11 GAX28713.1 - 0.006 16.0 6.1 0.011 15.2 6.1 1.3 1 0 0 1 1 1 1 Rabaptin-like protein YabA PF06156.13 GAX28713.1 - 0.013 16.1 1.1 0.035 14.8 1.1 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 GAX28713.1 - 0.016 15.4 7.2 0.038 14.2 7.1 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 GAX28713.1 - 0.071 13.6 4.9 0.25 11.8 4.9 1.9 1 0 0 1 1 1 0 Cell division protein ZapB STN1_2 PF09170.10 GAX28713.1 - 0.092 12.9 4.1 0.12 12.6 3.3 1.6 1 1 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 PI3K_P85_iSH2 PF16454.5 GAX28713.1 - 0.11 12.0 8.1 0.066 12.8 4.9 2.2 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cnn_1N PF07989.11 GAX28713.1 - 0.27 11.4 4.1 0.42 10.8 1.8 2.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 GAX28713.1 - 0.79 10.2 9.6 1.6 9.2 9.4 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region IZUMO PF15005.6 GAX28713.1 - 2.1 8.8 6.2 2 8.9 4.4 1.9 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DHR10 PF18595.1 GAX28713.1 - 2.2 8.3 10.7 5.8 7.0 10.7 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Cyclin_N PF00134.23 GAX28716.1 - 2.4e-15 56.4 0.3 3.7e-15 55.8 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyt-b5 PF00173.28 GAX28717.1 - 9.1e-09 35.3 0.0 1.4e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Taxilin PF09728.9 GAX28719.1 - 0.00075 18.8 16.6 0.00093 18.5 16.6 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4407 PF14362.6 GAX28719.1 - 0.035 13.4 16.6 0.042 13.2 16.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2353 PF09789.9 GAX28719.1 - 0.041 13.3 16.0 0.047 13.1 16.0 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.15 GAX28719.1 - 0.042 13.6 4.9 0.042 13.6 4.9 2.5 1 1 1 2 2 2 0 Septum formation initiator Mannitol_dh_C PF08125.13 GAX28719.1 - 0.055 12.9 3.8 0.07 12.6 3.8 1.3 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain UPF0242 PF06785.11 GAX28719.1 - 0.06 13.5 19.0 0.08 13.0 19.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus P4Ha_N PF08336.11 GAX28719.1 - 0.08 13.0 6.4 1.7 8.7 0.3 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region GAS PF13851.6 GAX28719.1 - 0.12 11.7 17.4 0.17 11.2 17.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 GAX28719.1 - 0.2 10.2 9.8 0.21 10.2 9.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A NBD_C PF17042.5 GAX28719.1 - 0.61 10.6 8.3 0.85 10.1 8.3 1.2 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain V_ATPase_I PF01496.19 GAX28719.1 - 0.75 7.6 8.7 0.79 7.6 8.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 GAX28719.1 - 0.91 10.0 17.6 3.9 7.9 17.6 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) IL2 PF00715.17 GAX28719.1 - 1.4 8.9 6.4 2.4 8.1 6.4 1.4 1 1 0 1 1 1 0 Interleukin 2 TMF_TATA_bd PF12325.8 GAX28719.1 - 1.5 9.1 18.9 3.3 7.9 18.9 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Rotamase PF00639.21 GAX28719.1 - 2.2 9.3 6.6 0.98 10.4 0.8 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain Spc24 PF08286.11 GAX28719.1 - 2.3 8.5 14.7 2.5 8.4 4.5 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 GAX28719.1 - 2.3 8.7 26.1 6.1 7.4 23.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 GAX28719.1 - 4 7.5 9.7 15 5.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1635 PF07795.11 GAX28719.1 - 4.8 7.0 19.7 0.37 10.6 8.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) Cdh1_DBD_1 PF18196.1 GAX28719.1 - 4.8 7.5 11.3 1.9 8.8 4.7 2.1 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 FUSC PF04632.12 GAX28719.1 - 4.9 5.6 9.1 5.7 5.3 9.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CRAL_TRIO PF00650.20 GAX28720.1 - 1.9e-29 102.4 0.0 3.8e-29 101.4 0.0 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAX28720.1 - 0.0023 18.1 0.1 0.0055 16.9 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAX28720.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Thioredoxin_4 PF13462.6 GAX28721.1 - 0.015 15.5 0.8 2 8.5 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin Het-C PF07217.11 GAX28721.1 - 0.04 12.5 0.2 0.085 11.4 0.2 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C NAD_binding_8 PF13450.6 GAX28723.1 - 4.1e-13 49.4 0.0 9.8e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX28723.1 - 9e-12 45.2 0.8 1.8e-05 24.5 0.4 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAX28723.1 - 1.6e-11 44.1 0.0 2.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAX28723.1 - 5.6e-08 32.3 0.4 7.6e-05 22.0 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 GAX28723.1 - 2.4e-07 29.8 0.2 0.0073 15.0 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 GAX28723.1 - 1.6e-05 24.2 0.1 3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAX28723.1 - 0.00013 21.3 1.1 0.00096 18.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX28723.1 - 0.00075 19.0 0.2 0.0013 18.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX28723.1 - 0.0088 16.6 0.1 0.22 12.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 GAX28723.1 - 0.11 11.0 0.0 0.3 9.6 0.0 1.6 2 0 0 2 2 2 0 GDP dissociation inhibitor PDZ PF00595.24 GAX28724.1 - 1.1e-06 28.9 0.1 2.1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAX28724.1 - 0.00022 21.0 0.1 0.00039 20.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX28724.1 - 0.00032 20.9 0.2 0.00089 19.5 0.2 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 GAX28724.1 - 0.15 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF2613 PF11021.8 GAX28724.1 - 0.5 10.5 3.2 0.56 10.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Podoplanin PF05808.11 GAX28724.1 - 1.7 8.7 7.1 0.19 11.8 0.4 2.5 1 1 2 3 3 3 0 Podoplanin EcoRII-C PF09019.11 GAX28727.1 - 0.029 14.4 0.8 0.067 13.3 0.8 1.6 1 0 0 1 1 1 0 EcoRII C terminal DUF2064 PF09837.9 GAX28728.1 - 4.6e-09 36.1 0.0 1.2e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2064) zf-RING_2 PF13639.6 GAX28729.1 - 5.6e-11 42.6 7.3 9.6e-11 41.8 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAX28729.1 - 2.1e-08 33.7 0.7 5e-08 32.5 0.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GAX28729.1 - 3.4e-06 27.0 4.3 3.4e-06 27.0 4.3 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAX28729.1 - 7e-06 26.0 3.1 7.4e-05 22.7 3.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 GAX28729.1 - 7.5e-05 22.8 5.5 0.00022 21.3 5.5 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 GAX28729.1 - 0.00023 21.0 4.6 0.00043 20.1 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAX28729.1 - 0.00025 20.8 6.7 0.0005 19.9 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAX28729.1 - 0.00033 20.9 10.9 0.0011 19.2 10.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAX28729.1 - 0.0078 16.1 3.0 0.017 15.0 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 GAX28729.1 - 0.022 15.0 0.4 0.058 13.6 0.4 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 GAX28729.1 - 0.04 13.9 4.6 0.085 12.8 4.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 GAX28729.1 - 0.05 13.7 5.8 0.1 12.8 5.8 1.5 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 GAX28729.1 - 0.079 12.8 0.7 0.16 11.8 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 GAX28729.1 - 0.083 12.5 6.1 0.17 11.5 6.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 GAX28729.1 - 0.74 9.8 6.4 8.4 6.4 0.9 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L30 PF00327.20 GAX28730.1 - 7.5e-21 73.8 0.8 1.4e-20 72.9 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 GAX28730.1 - 8e-16 58.1 15.2 1.4e-15 57.2 15.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain hGDE_N PF14699.6 GAX28730.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme NAPRTase_N PF17767.1 GAX28731.1 - 5.9e-34 117.1 0.0 1.1e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 GAX28731.1 - 1.3e-24 86.8 0.0 2.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 GAX28731.1 - 9.6e-11 41.7 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family E1-E2_ATPase PF00122.20 GAX28732.1 - 9.4e-44 149.1 0.1 2.1e-43 147.9 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAX28732.1 - 2.3e-35 122.8 0.0 5.2e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAX28732.1 - 2.7e-11 43.7 2.0 3.5e-07 30.6 0.1 3.1 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAX28732.1 - 1.4e-07 31.5 1.6 0.00096 19.0 0.3 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX28732.1 - 0.0067 16.8 0.1 0.029 14.8 0.1 2.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fer2_4 PF13510.6 GAX28732.1 - 0.26 11.3 2.3 0.7 10.0 0.4 2.5 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain S1 PF00575.23 GAX28733.1 - 6.5e-23 80.9 7.4 3.8e-07 30.3 0.4 7.2 7 1 0 7 7 7 4 S1 RNA binding domain GST_C PF00043.25 GAX28735.1 - 1.9e-09 37.6 0.0 3.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAX28735.1 - 2.2e-07 31.2 0.0 5.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAX28735.1 - 1.4e-06 28.4 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAX28735.1 - 6.4e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAX28735.1 - 0.00077 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAX28735.1 - 0.031 14.3 0.0 0.14 12.2 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Methyltransf_11 PF08241.12 GAX28736.1 - 3.5e-08 34.0 0.1 4.9e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28736.1 - 2.6e-07 30.5 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX28736.1 - 1.2e-06 29.1 0.1 1.8e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX28736.1 - 0.0032 18.2 0.0 0.0045 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX28736.1 - 0.0075 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family WD40 PF00400.32 GAX28738.1 - 5.1e-29 99.9 18.2 4.6e-06 27.3 0.5 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28738.1 - 2.1e-11 44.0 0.2 0.011 16.1 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX28738.1 - 0.00056 18.7 0.6 0.1 11.2 0.0 2.6 3 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 GAX28738.1 - 0.00088 19.7 1.6 0.055 14.0 0.0 4.2 5 1 0 5 5 5 1 PQQ-like domain WD40_like PF17005.5 GAX28738.1 - 0.00096 18.6 0.1 0.0091 15.4 0.0 2.4 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 GAX28738.1 - 0.0016 17.5 0.1 5.4 5.9 0.0 3.5 3 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein COX16 PF14138.6 GAX28739.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 WD40 PF00400.32 GAX28741.1 - 4.2e-30 103.3 17.3 2.8e-10 40.6 0.2 7.8 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28741.1 - 1.4e-15 57.4 0.0 0.00029 21.1 0.0 5.3 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAX28741.1 - 0.00078 19.4 0.0 0.012 15.5 0.0 2.6 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAX28741.1 - 0.0055 15.4 0.8 0.48 9.0 0.1 3.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX28741.1 - 0.098 11.6 0.1 2.2 7.1 0.0 2.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GAX28741.1 - 0.12 11.1 0.0 6.5 5.4 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like Roughex PF06020.11 GAX28741.1 - 2.6 7.1 7.0 3.9 6.5 7.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein YL1 PF05764.13 GAX28741.1 - 3.7 7.6 5.2 4.8 7.2 5.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Coatomer_WDAD PF04053.14 GAX28742.1 - 0.0092 15.1 0.0 3.2 6.7 0.0 3.1 3 0 0 3 3 3 2 Coatomer WD associated region bZIP_1 PF00170.21 GAX28743.1 - 6.3e-07 29.4 12.1 6.3e-07 29.4 12.1 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX28743.1 - 0.00021 21.3 13.2 0.00021 21.3 13.2 2.2 2 0 0 2 2 2 1 Basic region leucine zipper OrfB_IS605 PF01385.19 GAX28743.1 - 1.6 9.0 6.3 4.9 7.4 6.3 1.8 1 0 0 1 1 1 0 Probable transposase Mur_ligase_M PF08245.12 GAX28745.1 - 3e-07 30.6 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 GAX28745.1 - 3.4e-07 30.4 0.0 3.1e-06 27.4 0.0 2.4 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain ThylakoidFormat PF11264.8 GAX28746.1 - 7.5e-51 172.9 0.0 1.3e-50 172.2 0.0 1.3 1 0 0 1 1 1 1 Thylakoid formation protein Pterin_4a PF01329.19 GAX28747.1 - 5.8e-24 84.1 0.7 7.6e-24 83.7 0.7 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase COX16 PF14138.6 GAX28748.1 - 0.065 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 HSP90 PF00183.18 GAX28748.1 - 8.1 5.2 6.7 11 4.8 6.7 1.1 1 0 0 1 1 1 0 Hsp90 protein Cupin_8 PF13621.6 GAX28749.1 - 6.1e-30 104.8 5.8 1.1e-29 104.0 5.8 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX28749.1 - 3.3e-08 33.4 0.1 8.9e-08 32.0 0.1 1.7 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 GAX28749.1 - 0.0014 19.0 0.3 0.0037 17.7 0.0 1.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase Glyco_H_20C_C PF18088.1 GAX28749.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain DUF3522 PF12036.8 GAX28750.1 - 0.2 11.9 10.4 0.81 9.9 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) DnaJ_C PF01556.18 GAX28751.1 - 2.2e-38 131.7 3.4 4e-38 130.8 3.4 1.5 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX28751.1 - 3.6e-21 75.0 2.8 3.6e-21 75.0 2.8 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAX28751.1 - 1.5e-09 38.1 3.9 3.3e-09 37.0 3.9 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF5351 PF17302.2 GAX28751.1 - 0.091 13.0 3.6 4.9 7.4 1.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 GAX28751.1 - 0.18 11.8 3.7 0.78 9.8 3.7 2.0 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein MutS_V PF00488.21 GAX28752.1 - 2e-32 112.7 0.0 5.9e-32 111.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain V Smr PF01713.21 GAX28752.1 - 2.5e-12 47.0 0.0 6.3e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Smr domain T2SSE PF00437.20 GAX28752.1 - 0.00026 20.2 0.1 0.075 12.1 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_21 PF13304.6 GAX28752.1 - 0.00047 20.1 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MutS_III PF05192.18 GAX28752.1 - 0.0098 16.1 0.1 0.0098 16.1 0.1 3.1 2 2 0 2 2 2 1 MutS domain III Spc7 PF08317.11 GAX28752.1 - 0.52 9.1 21.4 0.03 13.2 14.4 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 GAX28752.1 - 1.1 9.6 12.5 0.041 14.2 3.2 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.9 GAX28752.1 - 1.3 9.3 7.8 0.27 11.5 3.6 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein SRP54 PF00448.22 GAX28753.1 - 1.6e-58 197.6 0.4 2.5e-58 196.9 0.4 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GAX28753.1 - 1.4e-09 38.0 0.0 7.8e-09 35.6 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 GAX28753.1 - 0.00022 21.7 0.7 0.0029 18.0 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain CbiA PF01656.23 GAX28753.1 - 0.00028 20.9 2.7 0.24 11.5 0.0 3.1 3 0 0 3 3 3 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 GAX28753.1 - 0.00033 20.8 0.1 0.0012 19.0 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX28753.1 - 0.00033 20.9 1.6 0.0014 18.9 0.0 2.6 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 GAX28753.1 - 0.0011 18.8 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAX28753.1 - 0.002 18.6 0.0 0.0063 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAX28753.1 - 0.0027 17.0 0.5 0.015 14.6 0.0 2.3 2 1 1 3 3 3 1 Zeta toxin MeaB PF03308.16 GAX28753.1 - 0.0045 16.0 0.1 0.013 14.5 0.1 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP-alpha_N PF04086.13 GAX28753.1 - 0.0046 16.9 7.5 0.0092 15.9 6.3 1.8 1 1 1 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal cobW PF02492.19 GAX28753.1 - 0.01 15.4 1.2 0.035 13.7 1.2 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 GAX28753.1 - 0.01 16.1 0.1 0.028 14.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 GAX28753.1 - 0.032 14.1 0.1 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 NTPase SDA1 PF05285.12 GAX28753.1 - 0.045 13.2 3.4 0.064 12.7 3.4 1.1 1 0 0 1 1 1 0 SDA1 AAA_24 PF13479.6 GAX28753.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX28753.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GAX28753.1 - 0.13 12.7 1.3 2.3 8.7 0.1 2.8 2 1 0 2 2 2 0 RNA helicase Rad17 PF03215.15 GAX28753.1 - 0.14 12.1 0.4 17 5.3 0.1 2.5 2 1 0 2 2 2 0 Rad17 P-loop domain 3Beta_HSD PF01073.19 GAX28754.1 - 0.0043 16.1 0.0 0.0058 15.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAX28754.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Synaptobrevin PF00957.21 GAX28755.1 - 3.9e-15 55.4 0.4 6.5e-15 54.7 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAX28755.1 - 1.4e-10 41.0 0.0 3.4e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 GAX28755.1 - 0.019 14.7 0.1 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region DUF21 PF01595.20 GAX28757.1 - 1.2e-27 96.7 1.1 1.9e-27 96.1 1.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Methyltransf_11 PF08241.12 GAX28758.1 - 4.7e-12 46.4 0.0 6.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX28758.1 - 7.8e-10 39.3 0.0 1.3e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX28758.1 - 1.7e-09 37.6 0.0 3.2e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX28758.1 - 0.04 14.6 0.0 0.099 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain UbiA PF01040.18 GAX28759.1 - 1.2e-31 109.9 19.0 1.6e-31 109.6 19.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ham1p_like PF01725.16 GAX28760.1 - 1.6e-42 145.5 0.0 1.9e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family PMM PF03332.13 GAX28761.1 - 3.9e-101 337.4 1.4 4.4e-101 337.2 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 GAX28761.1 - 4.9e-06 26.5 0.0 1.6e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 GAX28762.1 - 7e-52 176.3 0.7 1.3e-51 175.4 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX28762.1 - 5.8e-14 52.4 0.0 2.3e-13 50.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RanBP PF00641.18 GAX28762.1 - 4.3e-11 41.9 21.9 6.3e-07 28.6 4.7 3.1 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others Bromodomain PF00439.25 GAX28762.1 - 1.1e-10 41.4 0.2 3.1e-10 40.0 0.2 1.8 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 GAX28762.1 - 1.7e-10 41.2 0.0 7.5e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX28762.1 - 3e-08 33.6 0.0 7.8e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAX28762.1 - 0.00085 19.1 0.0 0.0067 16.1 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Vps36-NZF-N PF16988.5 GAX28762.1 - 1.3 8.5 7.2 8.6 5.8 0.9 3.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PriA_CRR PF18319.1 GAX28762.1 - 3.2 7.8 11.7 0.22 11.5 0.5 3.0 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain DZR PF12773.7 GAX28762.1 - 9 6.4 12.8 13 5.9 0.9 3.3 3 0 0 3 3 3 0 Double zinc ribbon Dus PF01207.17 GAX28763.1 - 4.9e-45 154.0 0.0 2.4e-42 145.1 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Ribosomal_L11_N PF03946.14 GAX28764.1 - 1.5e-20 72.8 0.2 2.4e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GAX28764.1 - 1.1e-17 64.2 0.1 2.3e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain MCPVI PF02993.14 GAX28764.1 - 0.014 15.2 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI PFK PF00365.20 GAX28767.1 - 7.9e-57 192.7 0.7 1.9e-56 191.5 0.1 1.7 2 0 0 2 2 2 1 Phosphofructokinase LSDAT_euk PF18139.1 GAX28767.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM DAGK_cat PF00781.24 GAX28767.1 - 0.096 12.3 0.4 0.68 9.6 0.1 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain TauE PF01925.19 GAX28769.1 - 3.2e-28 98.9 17.5 9.6e-15 54.9 0.2 2.9 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE Nup88 PF10168.9 GAX28769.1 - 0.0081 14.0 0.0 0.011 13.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore component EMC3_TMCO1 PF01956.16 GAX28769.1 - 0.047 13.4 0.1 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like G6B PF15096.6 GAX28769.1 - 0.18 11.6 0.2 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 G6B family DUF4834 PF16118.5 GAX28769.1 - 0.22 12.5 0.2 1.7 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) LRR19-TM PF15176.6 GAX28769.1 - 0.33 11.0 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Pox_A14 PF05767.12 GAX28769.1 - 0.78 9.9 8.4 14 5.9 0.0 4.6 5 1 1 6 6 6 0 Poxvirus virion envelope protein A14 ADH_zinc_N PF00107.26 GAX28770.1 - 2.2e-05 24.4 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 GAX28771.1 - 4e-19 69.0 0.0 8.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX28771.1 - 2.2e-15 56.7 0.0 4.1e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 GAX28771.1 - 0.0056 16.3 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 HypF_C PF17788.1 GAX28771.1 - 0.09 13.5 2.1 0.22 12.3 2.1 1.5 1 0 0 1 1 1 0 HypF Kae1-like domain Glyco_transf_24 PF18404.1 GAX28772.1 - 4.6e-138 459.1 3.1 9.5e-138 458.0 3.1 1.6 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 GAX28772.1 - 7.2e-29 101.5 0.0 6.4e-27 95.1 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 GAX28772.1 - 1e-15 57.9 1.8 2.3e-15 56.7 0.3 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 GAX28772.1 - 1.4e-13 50.9 0.0 7.5e-12 45.3 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 GAX28772.1 - 1.8e-11 44.3 0.0 4.4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 GAX28772.1 - 1.1e-08 35.0 0.2 3.8e-08 33.2 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 PAP_fibrillin PF04755.12 GAX28774.1 - 0.0029 17.6 0.1 0.0065 16.4 0.0 1.6 2 0 0 2 2 2 1 PAP_fibrillin TatC PF00902.18 GAX28776.1 - 0.017 14.9 1.0 0.031 14.1 1.0 1.3 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Sulf_transp PF04143.14 GAX28776.1 - 0.14 11.7 0.2 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 Sulphur transport TssO PF17561.2 GAX28776.1 - 0.28 11.3 3.2 20 5.3 0.0 3.7 4 0 0 4 4 4 0 Type VI secretion system, TssO NIF PF03031.18 GAX28777.1 - 1e-39 135.8 0.0 1.8e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.8 GAX28777.1 - 0.047 13.2 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) GTP_cyclohydroI PF01227.22 GAX28778.1 - 5e-72 241.1 1.1 5e-72 241.1 1.1 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase I QueF PF14489.6 GAX28778.1 - 0.0085 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein DUF4816 PF16086.5 GAX28779.1 - 0.21 11.5 13.5 1.6 8.7 1.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4816) Fer2 PF00111.27 GAX28780.1 - 1.8e-06 27.8 0.1 3.5e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Arv1 PF04161.13 GAX28781.1 - 6.1e-19 69.0 5.1 6.1e-19 69.0 5.1 1.5 1 1 0 1 1 1 1 Arv1-like family DZR PF12773.7 GAX28781.1 - 0.37 10.9 3.3 0.82 9.7 3.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_S24 PF00717.23 GAX28782.1 - 6e-08 32.5 0.0 2.5e-07 30.6 0.0 2.1 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 GAX28782.1 - 4.3e-07 29.8 0.0 8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Glyco_transf_49 PF13896.6 GAX28783.1 - 2.6e-35 122.3 0.7 5e-27 95.1 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DUF2371 PF10177.9 GAX28783.1 - 0.076 13.2 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) RXT2_N PF08595.11 GAX28785.1 - 0.068 13.2 0.1 0.068 13.2 0.1 5.4 6 0 0 6 6 6 0 RXT2-like, N-terminal Orthopox_A36R PF05950.11 GAX28785.1 - 0.1 12.7 5.3 1.9 8.7 2.1 2.5 2 0 0 2 2 2 0 Orthopoxvirus A36R protein DUF3991 PF13154.6 GAX28789.1 - 0.064 13.6 0.1 0.15 12.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3991) UCH PF00443.29 GAX28790.1 - 1.3e-68 231.3 0.1 4.9e-68 229.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX28790.1 - 2.3e-15 57.0 1.8 1.5e-08 34.6 0.0 3.6 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAX28790.1 - 9.9e-12 45.3 0.0 7e-10 39.4 0.0 3.0 1 1 0 1 1 1 1 DUSP domain zf-MYND PF01753.18 GAX28790.1 - 3.8e-07 30.1 18.8 3.8e-07 30.1 18.8 3.1 3 0 0 3 3 3 1 MYND finger TPR_2 PF07719.17 GAX28790.1 - 0.00035 20.4 9.0 0.27 11.5 0.2 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28790.1 - 0.0031 17.3 13.6 0.0069 16.2 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX28790.1 - 0.012 15.8 3.7 3.3 8.1 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 GAX28791.1 - 3.9e-07 30.0 14.4 1e-06 28.6 14.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAX28791.1 - 3.2e-06 26.9 13.9 7.6e-06 25.7 13.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAX28791.1 - 4.5e-06 26.4 18.0 1.2e-05 25.1 18.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX28791.1 - 2.4e-05 24.6 17.7 8.4e-05 22.8 17.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAX28791.1 - 0.0073 16.4 18.2 0.019 15.1 18.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAX28791.1 - 0.0089 15.8 23.4 0.0093 15.8 20.2 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX28791.1 - 0.028 14.4 17.3 0.068 13.1 17.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Band_7 PF01145.25 GAX28791.1 - 3.6 7.6 6.1 28 4.6 6.0 2.1 1 1 0 1 1 1 0 SPFH domain / Band 7 family Glyco_trans_1_2 PF13524.6 GAX28792.1 - 0.00074 19.9 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX28792.1 - 0.016 14.8 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Agglutinin PF07468.11 GAX28792.1 - 0.14 12.3 0.0 20 5.3 0.0 2.3 2 0 0 2 2 2 0 Agglutinin domain Sec6 PF06046.13 GAX28793.1 - 4.7e-20 71.5 1.4 2e-19 69.4 1.4 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec6 DUF3802 PF12290.8 GAX28793.1 - 0.0023 18.4 0.2 0.0092 16.5 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3802) FerA PF08165.11 GAX28793.1 - 0.1 12.5 0.9 3 7.9 0.1 3.0 2 0 0 2 2 2 0 FerA (NUC095) domain Neur_chan_memb PF02932.16 GAX28793.1 - 0.22 11.6 1.3 0.46 10.5 0.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CRAL_TRIO PF00650.20 GAX28794.1 - 1.1e-23 83.7 0.0 1.6e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAX28794.1 - 0.0054 16.9 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RNA_pol_Rpb4 PF03874.16 GAX28795.1 - 8.6e-16 58.4 1.3 1.2e-15 58.0 1.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 CHGN PF05679.16 GAX28795.1 - 0.018 13.9 0.4 0.023 13.6 0.4 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase DUF4205 PF13898.6 GAX28796.1 - 0.0014 17.6 0.4 0.027 13.4 0.4 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) UBA_4 PF14555.6 GAX28796.1 - 0.0017 18.2 0.1 0.0042 16.9 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain CDC27 PF09507.10 GAX28796.1 - 2.7 7.3 6.3 4.4 6.6 6.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 tRNA_bind PF01588.20 GAX28797.1 - 5.5e-09 36.0 0.5 1e-08 35.2 0.5 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Sulfotransfer_1 PF00685.27 GAX28797.1 - 3.6e-07 29.9 0.0 0.00047 19.7 0.0 2.5 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX28797.1 - 0.0087 16.5 0.0 0.59 10.5 0.0 2.5 1 1 0 2 2 2 1 Sulfotransferase family V-ATPase_H_C PF11698.8 GAX28798.1 - 2.5e-31 108.2 0.1 6.1e-31 107.0 0.1 1.7 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 GAX28798.1 - 2.7e-25 89.3 0.0 1.4e-24 87.0 0.0 2.0 2 1 1 3 3 3 1 V-ATPase subunit H Arm PF00514.23 GAX28798.1 - 1.2e-07 31.5 3.4 0.00047 20.1 0.1 4.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAX28798.1 - 0.03 14.7 2.2 0.97 9.9 0.1 3.0 3 0 0 3 3 3 0 HEAT repeats Cyt-b5 PF00173.28 GAX28798.1 - 0.18 12.0 0.0 0.77 9.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain Adeno_E3_CR2 PF02439.15 GAX28799.1 - 0.00071 19.3 4.0 0.0013 18.5 4.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 PDZ_6 PF17820.1 GAX28799.1 - 0.001 18.8 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAX28799.1 - 0.0018 18.6 0.0 0.005 17.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAX28799.1 - 0.029 14.7 0.1 0.069 13.5 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Longin PF13774.6 GAX28800.1 - 1.5e-16 60.2 0.0 3.1e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAX28800.1 - 8.1e-16 57.6 0.2 2e-15 56.3 0.1 1.7 2 0 0 2 2 2 1 Synaptobrevin DUF5600 PF18150.1 GAX28801.1 - 4.2e-32 110.9 0.2 8.8e-32 109.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 GAX28801.1 - 6.9e-15 55.5 0.0 3.2e-13 50.1 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 GAX28801.1 - 9.6e-14 51.0 0.1 1.7e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 GAX28801.1 - 1.6e-08 34.7 0.0 3.5e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 GAX28801.1 - 0.013 15.7 0.2 0.9 9.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 GAX28801.1 - 0.073 12.4 0.0 0.9 8.8 0.0 2.5 3 0 0 3 3 3 0 AIG1 family Gtr1_RagA PF04670.12 GAX28801.1 - 0.1 11.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAX28801.1 - 0.15 11.9 0.1 62 3.4 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 GAX28801.1 - 0.2 11.2 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.22 GAX28801.1 - 0.25 10.9 0.2 18 4.9 0.0 2.4 2 0 0 2 2 2 0 Ras family DUF5323 PF17257.2 GAX28802.1 - 5.8e-07 29.3 0.3 7.6e-07 28.9 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5323) S1 PF00575.23 GAX28803.1 - 2.7e-20 72.5 11.7 8.1e-14 51.7 0.6 3.1 2 1 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.6 GAX28803.1 - 0.049 13.7 0.1 1.3 9.1 0.0 2.7 2 1 0 2 2 2 0 S1 domain EXOSC1 PF10447.9 GAX28803.1 - 0.17 12.5 6.3 3.2 8.4 0.3 3.4 3 1 0 3 3 3 0 Exosome component EXOSC1/CSL4 LZ_Tnp_IS66 PF13007.7 GAX28803.1 - 2.3 9.0 7.7 11 6.9 4.2 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain TPR_12 PF13424.6 GAX28804.1 - 1.9e-51 172.3 16.4 1.8e-09 37.8 0.0 10.3 5 3 6 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28804.1 - 5.8e-26 88.5 14.1 0.066 13.4 0.0 14.0 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28804.1 - 7e-21 73.1 3.1 2.7 8.0 0.0 12.8 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_MalT PF17874.1 GAX28804.1 - 4.4e-18 65.8 0.1 0.0006 19.3 0.0 5.4 1 1 3 5 5 5 5 MalT-like TPR region TPR_8 PF13181.6 GAX28804.1 - 2.6e-16 58.4 9.6 0.16 12.2 0.0 11.1 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAX28804.1 - 4.6e-15 54.5 10.0 0.063 13.3 0.0 9.8 10 1 0 10 10 8 3 Tetratricopeptide repeat NB-ARC PF00931.22 GAX28804.1 - 2.4e-11 43.3 1.6 5.9e-11 42.0 1.6 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 GAX28804.1 - 8.7e-11 41.3 4.9 2.2 8.2 0.0 10.5 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX28804.1 - 6.2e-10 39.1 2.4 12 7.1 0.0 9.5 8 2 2 10 10 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX28804.1 - 9.3e-08 32.2 0.1 6.5 7.6 0.0 9.3 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAX28804.1 - 3e-07 31.0 1.6 4 8.2 0.0 8.1 8 2 2 11 11 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX28804.1 - 9.5e-07 28.4 0.3 26 4.6 0.0 6.7 6 0 0 6 6 6 0 TPR repeat ANAPC3 PF12895.7 GAX28804.1 - 1.2e-06 28.6 0.9 0.034 14.4 0.0 6.2 5 3 3 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAX28804.1 - 2.6e-06 27.9 6.1 0.36 11.4 0.0 6.9 6 3 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAX28804.1 - 0.00019 21.8 0.1 14 6.7 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX28804.1 - 0.0012 18.5 1.2 4 7.1 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat-like domain SPO22 PF08631.10 GAX28804.1 - 0.0032 17.0 0.5 0.026 14.0 0.0 2.9 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like RPN7 PF10602.9 GAX28804.1 - 0.018 14.8 1.0 6.6 6.4 0.0 4.1 3 1 0 3 3 3 0 26S proteasome subunit RPN7 MipZ PF09140.11 GAX28804.1 - 0.024 13.9 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ AAA_16 PF13191.6 GAX28804.1 - 0.032 14.6 0.0 0.032 14.6 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain TPR_17 PF13431.6 GAX28804.1 - 0.085 13.3 0.0 13 6.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GAX28804.1 - 0.11 12.5 8.1 5.4 7.2 0.1 4.9 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 zf-Tim10_DDP PF02953.15 GAX28805.1 - 1.7e-15 56.4 1.1 1.7e-15 56.4 1.1 2.1 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 GAX28805.1 - 0.11 12.4 1.4 0.18 11.8 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NAD_binding_10 PF13460.6 GAX28806.1 - 5.6e-14 52.5 0.0 6.9e-05 22.8 0.0 3.6 4 0 0 4 4 4 2 NAD(P)H-binding NmrA PF05368.13 GAX28806.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 GAX28806.1 - 0.0042 16.3 0.2 0.043 13.0 0.1 2.2 2 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.20 GAX28806.1 - 0.008 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 GAX28806.1 - 0.028 14.7 0.1 0.19 12.0 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAX28806.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAX28806.1 - 0.16 12.0 0.4 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Gp_dh_N PF00044.24 GAX28806.1 - 0.2 12.0 0.1 0.45 10.9 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain LCIB_C_CA PF18599.1 GAX28807.1 - 2.1e-65 220.1 0.0 2.5e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Phage_portal PF04860.12 GAX28807.1 - 0.18 10.9 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Phage portal protein VPS13_C PF16909.5 GAX28808.1 - 3.9e-44 150.5 0.1 1e-43 149.2 0.0 1.8 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 GAX28808.1 - 4e-34 118.5 0.0 1.5e-33 116.6 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Lung_7-TM_R PF06814.13 GAX28808.1 - 7.2e-30 104.2 17.6 4.9e-29 101.5 17.6 2.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor Chorein_N PF12624.7 GAX28808.1 - 3.6e-12 46.4 0.0 8.7e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAX28808.1 - 4.6e-05 23.7 0.1 0.002 18.4 0.1 2.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain GpcrRhopsn4 PF10192.9 GAX28808.1 - 8.1 5.8 19.0 0.094 12.1 10.8 1.9 2 1 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain HRI1 PF16815.5 GAX28809.1 - 0.0033 17.2 0.1 0.0052 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein HRI1 FtsL PF04999.13 GAX28809.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 Cell division protein FtsL DUF2116 PF09889.9 GAX28809.1 - 0.35 10.9 0.0 0.35 10.9 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) POP1 PF06978.11 GAX28810.1 - 1.2e-07 32.0 12.3 3.3e-07 30.5 12.3 1.6 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 GAX28810.1 - 1.5e-06 28.4 0.0 5.3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.11 GAX28810.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain 2_5_RNA_ligase2 PF13563.6 GAX28811.1 - 9.5e-31 106.8 0.0 1.5e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 GAX28811.1 - 8.4e-05 22.7 0.0 0.036 14.3 0.0 2.9 2 1 0 2 2 2 2 LigT like Phosphoesterase CPDase PF07823.11 GAX28811.1 - 0.025 14.3 0.0 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein Exo_endo_phos PF03372.23 GAX28812.1 - 5.2e-13 49.1 0.7 7.2e-13 48.6 0.7 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAX28812.1 - 0.029 14.2 0.1 3.4 7.5 0.0 3.2 4 0 0 4 4 4 0 Endonuclease-reverse transcriptase Oxysterol_BP PF01237.18 GAX28812.1 - 0.086 11.7 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein NosL PF05573.12 GAX28814.1 - 0.0046 17.3 1.1 22 5.4 0.0 3.5 2 1 1 3 3 3 3 NosL DUF3228 PF11539.8 GAX28814.1 - 0.062 12.8 0.0 7.2 6.1 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3228) Polysacc_deac_1 PF01522.21 GAX28815.1 - 7.5e-08 32.3 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Toxin_12 PF07740.12 GAX28815.1 - 0.028 15.1 12.3 0.028 15.1 12.3 4.7 5 0 0 5 5 5 0 Ion channel inhibitory toxin RSN1_7TM PF02714.15 GAX28816.1 - 5.8e-23 81.6 15.6 1.1e-22 80.7 15.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX28816.1 - 6.1e-10 39.1 6.0 6.4e-08 32.5 0.4 3.3 4 0 0 4 4 4 2 Late exocytosis, associated with Golgi transport Polysacc_deac_1 PF01522.21 GAX28817.1 - 0.00032 20.6 0.2 0.00097 19.0 0.1 1.9 2 1 0 2 2 2 1 Polysaccharide deacetylase FA_desaturase PF00487.24 GAX28818.1 - 4.7e-38 131.5 13.9 4.7e-38 131.5 13.9 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAX28818.1 - 1.8e-06 28.0 0.3 4.5e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HA PF03457.14 GAX28820.1 - 2.3e-38 130.3 2.1 7.5e-19 67.8 0.3 2.4 2 0 0 2 2 2 2 Helicase associated domain Mito_fiss_reg PF05308.11 GAX28820.1 - 0.034 14.2 1.6 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator FYDLN_acid PF09538.10 GAX28820.1 - 0.049 14.3 3.4 0.051 14.3 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 GAX28820.1 - 3.9 5.5 7.1 5.6 4.9 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 GAX28820.1 - 4.2 7.8 9.3 8.4 6.9 9.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ENTH PF01417.20 GAX28822.1 - 0.00088 19.3 0.0 0.088 12.9 0.0 2.5 2 0 0 2 2 2 2 ENTH domain HEAT_2 PF13646.6 GAX28822.1 - 0.12 12.8 0.8 3.1 8.2 0.3 2.8 2 1 1 3 3 3 0 HEAT repeats HSF_DNA-bind PF00447.17 GAX28823.1 - 7.9e-23 80.9 0.1 3.4e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Ribosomal_S25 PF03297.15 GAX28824.1 - 4.9e-37 126.2 1.0 5.4e-37 126.0 1.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein GntR PF00392.21 GAX28824.1 - 0.031 13.9 0.2 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 GAX28824.1 - 0.058 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Polysacc_deac_1 PF01522.21 GAX28825.1 - 2.4e-10 40.4 0.0 7e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase CBM_14 PF01607.24 GAX28825.1 - 1.1e-07 31.9 2.4 1.1e-07 31.9 2.4 2.9 2 1 0 3 3 3 1 Chitin binding Peritrophin-A domain BRCA-2_OB1 PF09103.10 GAX28826.1 - 7.4e-30 103.4 0.0 1.7e-29 102.3 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 GAX28826.1 - 1.5e-10 41.0 0.0 4.4e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 BRCA2, helical zf-RanBP PF00641.18 GAX28826.1 - 4.8e-09 35.4 1.8 4.8e-09 35.4 1.8 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others BRCA2 PF00634.18 GAX28826.1 - 1.3e-06 27.9 18.0 2.8 7.7 0.1 7.8 7 0 0 7 7 7 5 BRCA2 repeat Pkinase PF00069.25 GAX28827.1 - 9e-59 199.0 0.0 1.7e-58 198.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX28827.1 - 6.8e-44 147.9 0.6 4.8e-16 58.6 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX28827.1 - 2.1e-36 125.6 0.0 3.4e-35 121.6 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Cupin_2 PF07883.11 GAX28827.1 - 6.1e-06 25.9 1.6 0.29 10.9 0.0 3.6 3 0 0 3 3 3 3 Cupin domain APH PF01636.23 GAX28827.1 - 0.0022 18.0 0.0 0.0071 16.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Phasin_2 PF09361.10 GAX28827.1 - 0.14 12.5 0.9 0.87 9.9 0.6 2.3 1 1 1 2 2 2 0 Phasin protein SelR PF01641.18 GAX28828.1 - 0.001 19.1 0.6 0.0035 17.4 0.6 2.0 1 1 0 1 1 1 1 SelR domain IL3Ra_N PF18611.1 GAX28828.1 - 0.069 13.2 2.5 7.1 6.7 0.3 2.2 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain RRM_1 PF00076.22 GAX28829.1 - 5.1e-24 83.9 0.1 9.6e-24 83.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 GAX28829.1 - 1.7e-10 40.3 8.7 3.7e-10 39.2 8.7 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 GAX28829.1 - 7.4e-06 26.3 2.7 7.7e-06 26.3 0.3 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.6 GAX28829.1 - 0.0019 17.8 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ThiP_synth PF10120.9 GAX28829.1 - 0.0084 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Thiamine-phosphate synthase DUF1866 PF08952.11 GAX28829.1 - 0.017 14.9 0.0 0.037 13.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 GAX28829.1 - 0.031 14.1 0.0 0.17 11.7 0.0 2.0 1 1 1 2 2 2 0 Occluded RNA-recognition motif MIP PF00230.20 GAX28830.1 - 2.8e-57 194.0 14.0 3.9e-57 193.6 14.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Yae1_N PF09811.9 GAX28831.1 - 2.9e-09 36.5 25.2 0.15 11.8 0.4 6.2 2 1 2 4 4 4 4 Essential protein Yae1, N terminal Rick_17kDa_Anti PF05433.15 GAX28831.1 - 0.018 14.9 0.9 0.018 14.9 0.9 2.6 2 1 0 2 2 2 0 Glycine zipper 2TM domain MspA PF09203.11 GAX28831.1 - 0.22 11.3 2.0 1.6 8.6 2.0 2.0 1 1 0 1 1 1 0 MspA CAP_GLY PF01302.25 GAX28831.1 - 2.4 8.2 4.2 21 5.2 4.2 2.7 1 1 0 1 1 1 0 CAP-Gly domain DUF3806 PF12713.7 GAX28831.1 - 3.8 7.3 5.1 20 5.0 0.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3806) TMEM65 PF10507.9 GAX28833.1 - 1.2e-38 131.4 4.1 2.2e-38 130.5 4.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 ACT PF01842.25 GAX28833.1 - 0.00021 21.0 0.0 0.00048 19.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GAX28833.1 - 0.061 13.9 0.0 0.2 12.3 0.0 1.8 1 0 0 1 1 1 0 ACT domain HTH_35 PF13693.6 GAX28833.1 - 0.17 12.0 0.1 30 4.7 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding PspB PF06667.12 GAX28833.1 - 0.21 11.7 1.6 0.98 9.5 1.6 2.0 1 1 0 1 1 1 0 Phage shock protein B Snf7 PF03357.21 GAX28834.1 - 3.1e-23 82.3 26.1 3.4e-23 82.1 25.4 1.4 1 1 0 1 1 1 1 Snf7 YlqD PF11068.8 GAX28834.1 - 0.00065 20.1 6.9 0.00065 20.1 6.9 2.8 1 1 1 2 2 2 1 YlqD protein MMR_HSR1_Xtn PF16897.5 GAX28834.1 - 0.028 14.4 0.5 0.081 12.9 0.5 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain QRPTase_C PF01729.19 GAX28834.1 - 0.3 10.9 8.6 0.12 12.1 5.2 2.0 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF3138 PF11336.8 GAX28834.1 - 4.5 5.8 7.9 6.1 5.3 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CP12 PF02672.15 GAX28835.1 - 1.6e-15 57.6 14.1 1.3e-09 38.6 0.9 2.8 2 2 1 3 3 3 2 CP12 domain SOAR PF16533.5 GAX28835.1 - 0.017 15.1 1.7 5 7.1 0.0 3.1 2 1 0 2 2 2 0 STIM1 Orai1-activating region Dak2 PF02734.17 GAX28835.1 - 0.11 12.4 9.1 0.65 9.9 2.8 2.1 1 1 1 2 2 2 0 DAK2 domain T2SSM PF04612.12 GAX28835.1 - 0.85 9.7 6.3 0.19 11.8 0.8 2.3 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Neur_chan_memb PF02932.16 GAX28835.1 - 0.86 9.6 3.2 1.1 9.3 3.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PSK_trans_fac PF07704.11 GAX28835.1 - 1.9 9.3 12.6 0.58 10.9 1.3 3.1 1 1 2 3 3 3 0 Rv0623-like transcription factor Ribosomal_S26e PF01283.19 GAX28836.1 - 1.4e-48 163.8 6.4 1.5e-48 163.7 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf-C2HE PF16278.5 GAX28838.1 - 0.0014 19.0 0.1 0.0039 17.6 0.1 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_10 PF10058.9 GAX28838.1 - 0.01 15.6 0.4 0.01 15.6 0.4 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein SNX17_FERM_C PF18116.1 GAX28838.1 - 0.095 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain zf-MYND PF01753.18 GAX28838.1 - 0.46 10.6 26.3 0.073 13.2 18.2 3.0 3 1 1 4 4 4 0 MYND finger Acid_PPase PF12689.7 GAX28839.1 - 8.9e-39 133.0 0.0 2.3e-38 131.7 0.0 1.7 1 1 0 1 1 1 1 Acid Phosphatase CSD PF00313.22 GAX28839.1 - 7.5e-10 38.5 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain S1_2 PF13509.6 GAX28839.1 - 0.003 17.6 0.1 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 S1 domain ASCH PF04266.14 GAX28839.1 - 0.014 16.0 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 ASCH domain DUF705 PF05152.12 GAX28839.1 - 0.13 11.7 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Peptidase_M43 PF05572.13 GAX28840.1 - 2.6e-12 46.9 0.0 5.2e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A DUF4953 PF16313.5 GAX28840.1 - 0.0066 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Met-zincin Reprolysin_4 PF13583.6 GAX28840.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX28840.1 - 0.024 14.8 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX28840.1 - 0.026 15.0 0.0 0.048 14.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAX28840.1 - 0.19 10.6 0.3 0.29 10.0 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 GAX28840.1 - 0.21 11.4 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 Matrixin V-ATPase_H_C PF11698.8 GAX28841.1 - 7.2e-37 126.1 0.0 2.1e-36 124.6 0.0 1.9 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 GAX28841.1 - 5e-30 104.9 0.0 2.4e-29 102.6 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 GAX28841.1 - 7e-06 25.9 7.3 0.011 15.7 0.7 4.4 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAX28841.1 - 0.023 15.1 1.9 0.082 13.3 0.1 2.9 3 0 0 3 3 3 0 HEAT repeats DRIM PF07539.12 GAX28841.1 - 0.037 12.3 0.0 0.078 11.3 0.0 1.4 1 0 0 1 1 1 0 Down-regulated in metastasis DUF2451 PF10474.9 GAX28842.1 - 2.3e-28 99.6 0.0 1.2e-27 97.2 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) PAH PF02671.21 GAX28842.1 - 0.44 10.7 2.0 3.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Paired amphipathic helix repeat TPR_12 PF13424.6 GAX28843.1 - 4.3e-11 42.9 12.5 4.8e-05 23.6 2.6 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28843.1 - 1.4e-07 31.0 3.0 0.003 17.3 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX28843.1 - 4.6e-06 26.3 11.0 0.018 15.1 0.2 5.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX28843.1 - 0.00067 19.7 5.7 1.3 9.4 0.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX28843.1 - 0.0015 18.1 5.1 0.071 12.8 0.8 3.5 4 0 0 4 4 4 1 TPR repeat SNAP PF14938.6 GAX28843.1 - 0.0028 17.1 2.6 0.012 15.0 2.3 2.1 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 GAX28843.1 - 0.0052 16.6 13.4 4.5 7.3 0.2 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAX28843.1 - 0.0063 16.2 10.2 0.028 14.1 0.3 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GAX28843.1 - 0.0067 16.5 2.5 0.051 13.7 0.5 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAX28843.1 - 0.014 14.6 2.2 0.014 14.6 2.2 2.7 2 2 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX28843.1 - 0.016 16.0 18.0 3.9 8.5 1.0 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX28843.1 - 0.019 15.0 6.5 11 6.3 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Thioesterase PF00975.20 GAX28843.1 - 0.075 13.1 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain TPR_16 PF13432.6 GAX28843.1 - 0.089 13.5 18.4 0.72 10.5 2.7 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat CBP_BcsR PF10945.8 GAX28843.1 - 0.33 10.5 4.5 0.49 9.9 2.4 2.4 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsR NDUF_B6 PF09782.9 GAX28844.1 - 0.056 13.6 0.2 0.094 12.8 0.2 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit ABC_tran PF00005.27 GAX28845.1 - 1.1e-41 142.5 4.9 3e-20 73.1 0.1 3.8 4 1 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAX28845.1 - 3.5e-22 78.2 6.0 3.5e-22 78.2 6.0 3.0 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 GAX28845.1 - 1.4e-14 54.6 8.0 0.0023 17.8 0.1 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX28845.1 - 8.1e-13 48.3 1.9 0.00015 21.3 0.0 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX28845.1 - 3.1e-07 30.8 1.2 0.0018 18.5 0.0 3.7 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.6 GAX28845.1 - 8.1e-07 28.7 0.1 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 GAX28845.1 - 9.3e-07 28.9 0.0 0.026 14.4 0.1 2.6 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 GAX28845.1 - 1.4e-06 28.3 0.1 0.027 14.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAX28845.1 - 3.2e-06 27.7 1.0 0.042 14.2 0.2 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 GAX28845.1 - 3.4e-05 24.3 0.1 0.41 11.1 0.0 3.5 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAX28845.1 - 3.9e-05 23.9 0.3 0.35 11.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAX28845.1 - 4.8e-05 23.4 1.3 0.27 11.3 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 GAX28845.1 - 5.2e-05 23.8 0.1 0.0083 16.6 0.0 4.1 5 0 0 5 5 3 2 AAA domain AAA_15 PF13175.6 GAX28845.1 - 6.8e-05 22.7 0.2 0.19 11.4 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 GAX28845.1 - 0.00024 20.9 2.9 6.7 6.4 0.1 4.5 4 1 0 4 4 4 0 AAA domain AAA_30 PF13604.6 GAX28845.1 - 0.00025 20.8 0.0 0.56 9.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX28845.1 - 0.00059 20.4 0.9 0.78 10.3 0.0 3.3 3 1 0 3 3 3 1 AAA domain Rhodanese PF00581.20 GAX28845.1 - 0.00083 19.9 0.0 2.8 8.5 0.0 3.8 3 1 1 4 4 4 1 Rhodanese-like domain RNA_helicase PF00910.22 GAX28845.1 - 0.0012 19.2 0.7 2.8 8.4 0.0 3.6 3 0 0 3 3 3 1 RNA helicase Roc PF08477.13 GAX28845.1 - 0.0017 18.6 0.0 1.3 9.3 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 GAX28845.1 - 0.0021 17.3 0.0 0.66 9.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 GAX28845.1 - 0.0028 17.8 0.8 0.75 10.0 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_27 PF13514.6 GAX28845.1 - 0.0054 16.4 1.1 1.1 8.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 GAX28845.1 - 0.0057 16.7 2.2 2.8 8.0 0.0 3.0 3 0 0 3 3 3 2 Dynamin family NTPase_1 PF03266.15 GAX28845.1 - 0.0059 16.5 0.4 1.3 8.9 0.3 3.1 3 0 0 3 3 3 1 NTPase Zeta_toxin PF06414.12 GAX28845.1 - 0.0069 15.7 0.1 4.7 6.5 0.1 2.7 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 GAX28845.1 - 0.011 15.7 0.1 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 GAX28845.1 - 0.012 15.1 0.0 0.79 9.2 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_14 PF13173.6 GAX28845.1 - 0.015 15.3 0.0 4.3 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 GAX28845.1 - 0.018 15.4 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAX28845.1 - 0.019 14.6 0.6 4.9 6.7 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 GAX28845.1 - 0.031 13.8 0.0 23 4.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 GAX28845.1 - 0.045 13.1 0.1 0.82 9.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 GAX28845.1 - 0.05 12.7 0.0 0.27 10.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 GAX28845.1 - 0.087 12.7 0.0 9.7 6.0 0.0 2.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 GAX28845.1 - 0.14 12.3 5.8 21 5.1 0.0 4.1 4 0 0 4 4 4 0 Helicase HerA, central domain PduV-EutP PF10662.9 GAX28845.1 - 0.14 11.9 0.3 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 GAX28845.1 - 5.9 5.4 11.5 6.7 5.2 0.0 3.9 4 1 0 4 4 4 0 AAA domain GAS PF13851.6 GAX28846.1 - 0.0002 20.8 15.5 0.0002 20.8 15.5 4.7 1 1 3 4 4 4 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 GAX28846.1 - 0.00026 20.9 19.5 0.00026 20.9 19.5 5.5 1 1 4 5 5 5 3 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 GAX28846.1 - 0.0022 18.0 3.1 0.0022 18.0 3.1 6.0 5 1 1 6 6 6 2 bZIP transcription factor APG6_N PF17675.1 GAX28846.1 - 0.013 16.1 21.0 0.013 16.1 21.0 6.8 3 1 3 6 6 6 0 Apg6 coiled-coil region AvrLm4-7 PF18661.1 GAX28846.1 - 0.34 12.0 1.9 14 6.8 0.3 2.8 2 0 0 2 2 2 0 Avirulence Effector AvrLm4-7 DUF4250 PF14056.6 GAX28846.1 - 0.88 9.6 3.4 4.7 7.2 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) TSC22 PF01166.18 GAX28846.1 - 1.4 9.3 27.2 2.7 8.4 1.9 5.8 3 1 2 5 5 5 0 TSC-22/dip/bun family DUF948 PF06103.11 GAX28846.1 - 2.2 8.6 23.5 0.24 11.7 2.6 4.1 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 GAX28847.1 - 9.3e-15 55.0 0.0 1.9e-09 38.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX28847.1 - 3.9e-12 45.2 1.4 0.014 15.9 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 GAX28847.1 - 8.2e-10 39.0 0.5 2.5e-06 27.9 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAX28847.1 - 8.4e-10 38.7 5.3 0.0088 16.4 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAX28847.1 - 8e-09 35.6 2.5 1.6e-05 25.1 0.0 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) DUF3568 PF12092.8 GAX28847.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Ank_5 PF13857.6 GAX28848.1 - 2.1e-09 37.4 0.8 0.0044 17.3 0.0 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX28848.1 - 3.5e-06 27.5 0.1 0.13 12.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX28848.1 - 3.6e-06 27.5 0.0 0.013 16.1 0.0 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAX28848.1 - 0.00014 22.1 0.0 0.83 10.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAX28848.1 - 0.00015 22.0 0.2 1 9.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat UQ_con PF00179.26 GAX28849.1 - 0.0012 18.4 1.1 0.004 16.8 1.1 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Mac-1 PF09028.10 GAX28849.1 - 0.29 10.2 0.0 0.45 9.5 0.0 1.2 1 0 0 1 1 1 0 Mac 1 TPR_2 PF07719.17 GAX28851.1 - 0.0026 17.7 0.2 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX28851.1 - 0.0093 16.1 0.3 0.87 10.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAX28851.1 - 0.013 16.0 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28851.1 - 0.072 12.9 0.1 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX28851.1 - 0.31 11.8 1.3 24 5.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX28851.1 - 0.82 10.7 2.6 9.3 7.4 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 GAX28852.1 - 1.1e-16 61.5 0.0 2.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 GAX28852.1 - 7.5e-12 45.6 22.4 1.2e-05 25.8 3.1 2.7 2 0 0 2 2 2 2 ShK domain-like LRR_8 PF13855.6 GAX28853.1 - 2e-14 53.1 16.2 9.5e-05 22.1 0.1 5.0 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAX28853.1 - 2.3e-08 34.2 15.7 0.035 14.5 1.1 6.2 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX28853.1 - 0.0052 17.1 11.2 29 5.7 0.0 8.1 8 1 1 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 GAX28853.1 - 5.3 7.3 12.7 43 4.5 0.0 6.3 7 0 0 7 7 7 0 Leucine Rich repeat ABC1 PF03109.16 GAX28854.1 - 1.4e-24 86.5 0.0 4.1e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family FAE1_CUT1_RppA PF08392.12 GAX28855.1 - 9.2e-106 353.4 0.0 5.2e-105 350.9 0.0 1.9 1 1 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 GAX28855.1 - 5.1e-13 49.0 0.0 1.9e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 GAX28855.1 - 1.8e-12 47.5 0.0 3.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.10 GAX28855.1 - 3.7e-07 29.9 0.0 8.6e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 GAX28855.1 - 0.01 14.6 0.5 0.25 10.0 0.1 2.3 1 1 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DUF1967 PF09269.11 GAX28855.1 - 0.019 14.9 0.0 0.34 10.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Chal_sti_synt_N PF00195.19 GAX28855.1 - 0.04 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Peptidase_M43 PF05572.13 GAX28856.1 - 1.5e-11 44.4 0.0 3.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX28856.1 - 2.1e-05 24.8 4.5 2.9e-05 24.3 2.5 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAX28856.1 - 0.00034 20.3 0.1 0.00095 18.9 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAX28856.1 - 0.00047 20.7 0.0 0.00095 19.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX28856.1 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAX28856.1 - 0.023 13.6 0.4 0.037 13.0 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M7 PF02031.16 GAX28856.1 - 0.033 14.3 0.3 0.11 12.6 0.3 1.9 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DUF4953 PF16313.5 GAX28856.1 - 0.058 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 GAX28856.1 - 0.072 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin WD40 PF00400.32 GAX28857.1 - 1.5e-42 142.8 22.5 7.2e-07 29.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX28857.1 - 4.1e-09 36.6 0.4 0.2 12.0 0.0 5.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAX28857.1 - 1.2e-05 25.2 0.3 1 9.4 0.0 4.9 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 GAX28857.1 - 0.00024 19.9 4.8 1.3 7.6 0.1 3.8 1 1 1 4 4 4 3 Nucleoporin Nup120/160 Peptidase_M43 PF05572.13 GAX28858.1 - 3.1e-13 49.9 0.0 5.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX28858.1 - 0.00022 21.5 0.7 0.00038 20.7 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX28858.1 - 0.0026 18.3 0.0 0.0076 16.8 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX28858.1 - 0.0047 16.6 0.1 0.0089 15.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like GerE PF00196.19 GAX28858.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Peptidase_M7 PF02031.16 GAX28858.1 - 0.026 14.6 0.5 0.059 13.5 0.5 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.24 GAX28858.1 - 0.034 14.0 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 GAX28858.1 - 0.034 14.0 0.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAX28858.1 - 0.052 12.5 0.3 0.082 11.8 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 GAX28858.1 - 0.078 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Met-zincin HECT PF00632.25 GAX28859.1 - 2.1e-81 273.8 0.1 4.1e-81 272.8 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4709 PF15821.5 GAX28859.1 - 0.054 13.8 0.3 0.75 10.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) Glyco_hydro_18 PF00704.28 GAX28860.1 - 1.8e-17 64.1 0.2 3.3e-17 63.2 0.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 GAX28860.1 - 9.6e-10 38.5 1.9 9.6e-10 38.5 1.9 2.4 3 0 0 3 3 3 1 Chitin binding Peritrophin-A domain GTP_EFTU PF00009.27 GAX28861.1 - 1.2e-46 158.7 0.0 1.9e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAX28861.1 - 3.6e-09 36.5 0.0 9.4e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GAX28861.1 - 3.2e-05 23.9 0.0 8.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II adh_short PF00106.25 GAX28863.1 - 2.3e-31 108.8 0.1 3e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28863.1 - 6.7e-23 81.5 0.1 8.2e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX28863.1 - 0.0042 17.0 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Chloroa_b-bind PF00504.21 GAX28865.1 - 4.6e-39 134.5 0.0 5.8e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CLP_protease PF00574.23 GAX28866.1 - 6.7e-48 163.0 0.0 9.1e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Clp protease TPR_2 PF07719.17 GAX28867.1 - 1.1e-05 25.1 10.1 0.0075 16.3 2.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX28867.1 - 2.3e-05 23.9 6.1 0.015 15.0 3.1 3.2 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 GAX28867.1 - 6.6e-05 23.4 4.4 0.0059 17.3 0.3 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX28867.1 - 0.0086 16.4 0.7 21 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 GAX28867.1 - 0.018 13.4 0.0 0.025 13.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_16 PF13432.6 GAX28867.1 - 0.042 14.5 9.8 0.18 12.5 0.4 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX28867.1 - 0.081 12.8 8.5 0.065 13.1 1.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX28867.1 - 0.81 10.5 5.2 19 6.1 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX28867.1 - 1 9.9 5.9 12 6.4 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Proteasome PF00227.26 GAX28868.1 - 1.3e-44 152.0 0.3 1.6e-44 151.7 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_18 PF00704.28 GAX28869.1 - 1.8e-15 57.5 0.0 2.2e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CSRNP_N PF16019.5 GAX28869.1 - 0.41 10.5 2.1 0.66 9.8 2.1 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAD_binding_1 PF00667.20 GAX28871.1 - 7e-25 87.9 0.0 7.6e-23 81.2 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAX28871.1 - 2.6e-20 73.1 0.0 3.9e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAX28871.1 - 1.1e-11 45.3 0.0 1.5e-09 38.5 0.0 2.9 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Prismane PF03063.20 GAX28872.1 - 5.4e-139 464.2 1.1 6.2e-139 464.0 1.1 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family Guanylate_cyc PF00211.20 GAX28873.1 - 3.4e-48 163.7 0.0 6.6e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 GAX28873.1 - 2e-31 109.6 0.2 4.2e-31 108.5 0.2 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Thiolase_N PF00108.23 GAX28874.1 - 1.7e-72 243.9 1.3 2.3e-72 243.5 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAX28874.1 - 2.4e-46 156.4 0.1 1.6e-45 153.7 0.1 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 GAX28874.1 - 0.021 14.7 3.9 0.93 9.4 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III INCENP_ARK-bind PF03941.15 GAX28875.1 - 2.1e-15 56.4 0.5 5.2e-15 55.1 0.5 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAP PF02037.27 GAX28875.1 - 3.9e-05 23.3 0.0 3.9e-05 23.3 0.0 2.2 3 0 0 3 3 3 1 SAP domain Peptidase_S8 PF00082.22 GAX28876.1 - 4.1e-35 121.5 11.3 1.8e-34 119.4 11.3 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAX28876.1 - 0.0012 19.5 0.1 0.0039 17.8 0.1 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF637 PF04830.13 GAX28876.1 - 0.018 14.8 0.4 0.034 14.0 0.4 1.4 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) UPF0506 PF11703.8 GAX28876.1 - 0.18 12.2 9.5 0.46 10.9 9.5 1.7 1 0 0 1 1 1 0 UPF0506 Conotoxin_I2 PF17557.2 GAX28876.1 - 2 8.6 11.1 3.6 7.8 11.1 1.4 1 0 0 1 1 1 0 I2-superfamily conotoxins Toxin_23 PF08093.11 GAX28876.1 - 6.7 6.9 9.9 18 5.6 9.9 1.7 1 0 0 1 1 1 0 Magi 5 toxic peptide family Mito_carr PF00153.27 GAX28877.1 - 1.5e-48 162.7 3.5 8.4e-19 67.3 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Tubulin_3 PF14881.6 GAX28878.1 - 0.00017 21.3 0.8 0.0028 17.3 0.1 2.8 2 1 0 2 2 2 1 Tubulin domain Tubulin PF00091.25 GAX28878.1 - 0.015 15.5 0.0 2.9 8.0 0.0 2.8 3 0 0 3 3 3 0 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 GAX28878.1 - 0.017 15.4 0.2 0.017 15.4 0.2 3.0 2 2 0 2 2 2 0 Misato Segment II tubulin-like domain Transket_pyr PF02779.24 GAX28879.1 - 1.1e-44 152.2 0.1 1.7e-44 151.6 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX28879.1 - 7.1e-42 142.2 0.0 1.8e-41 140.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 GAX28879.1 - 0.003 17.9 0.0 0.024 15.0 0.0 2.3 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II EXS PF03124.14 GAX28880.1 - 6.9e-49 166.9 20.3 9e-49 166.6 20.3 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAX28880.1 - 9.4e-30 104.8 13.8 1.4e-29 104.2 13.8 1.2 1 0 0 1 1 1 1 SPX domain RhoGEF PF00621.20 GAX28880.1 - 0.7 10.1 4.1 1.3 9.2 0.1 2.7 2 1 0 2 2 2 0 RhoGEF domain Sep15_SelM PF08806.11 GAX28881.1 - 2.4e-08 34.0 0.4 4.6e-08 33.1 0.0 1.7 2 1 0 2 2 2 1 Sep15/SelM redox domain Bacillus_HBL PF05791.11 GAX28881.1 - 0.029 14.2 1.5 0.061 13.2 0.4 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Sulfotransfer_4 PF17784.1 GAX28882.1 - 3.5e-07 30.3 0.0 5.9e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX28882.1 - 1.8e-06 28.5 0.1 0.0025 18.2 0.1 2.5 1 1 0 2 2 2 2 Sulfotransferase family Ank_4 PF13637.6 GAX28883.1 - 1.3e-08 35.2 0.1 0.009 16.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX28883.1 - 1.4e-08 35.1 0.0 1.8e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAX28883.1 - 9.1e-08 32.2 0.5 0.011 16.1 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAX28883.1 - 8e-07 28.9 0.2 0.054 14.1 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAX28883.1 - 1.2e-05 25.4 0.3 0.053 13.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DctA-YdbH PF11739.8 GAX28883.1 - 0.063 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Dicarboxylate transport DNA_pol3_gamma3 PF12169.8 GAX28883.1 - 0.076 12.9 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Clp_N PF02861.20 GAX28883.1 - 0.085 13.0 0.0 23 5.2 0.0 2.7 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component MOZART1 PF12554.8 GAX28883.1 - 0.099 12.4 0.1 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Pep_deformylase PF01327.21 GAX28883.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase Abhydrolase_6 PF12697.7 GAX28884.1 - 1.5e-06 28.9 4.4 2.7e-06 28.2 0.2 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAX28884.1 - 5.4e-06 26.4 0.2 9.7e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAX28884.1 - 0.0001 21.8 0.0 0.088 12.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAX28884.1 - 0.0021 17.4 0.0 0.013 14.8 0.0 2.2 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF676 PF05057.14 GAX28884.1 - 0.0026 17.3 0.0 0.0079 15.7 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.16 GAX28884.1 - 0.052 13.3 0.0 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 GAX28884.1 - 0.058 13.3 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 GAX28884.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) EamA PF00892.20 GAX28885.1 - 4.1e-26 91.8 21.4 2.1e-14 53.8 5.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAX28885.1 - 0.00044 19.7 5.3 0.0065 15.9 0.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF202 PF02656.15 GAX28885.1 - 0.25 11.8 0.1 0.25 11.8 0.1 4.7 3 2 1 4 4 4 0 Domain of unknown function (DUF202) Cupin_4 PF08007.12 GAX28886.1 - 2e-56 191.8 0.1 2.4e-56 191.5 0.1 1.1 1 0 0 1 1 1 1 Cupin superfamily protein AraC_binding PF02311.19 GAX28886.1 - 0.00094 19.1 0.0 0.0039 17.1 0.0 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 GAX28886.1 - 0.0043 16.7 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 GAX28886.1 - 0.0046 16.6 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 GAX28886.1 - 0.012 15.3 0.0 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 Cupin-like domain Telomere_Sde2_2 PF13297.6 GAX28886.1 - 0.15 11.7 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 0 Telomere stability C-terminal SET PF00856.28 GAX28887.1 - 3.1e-08 34.2 0.0 0.00011 22.7 0.0 3.5 2 1 0 2 2 2 2 SET domain Radical_SAM PF04055.21 GAX28889.1 - 5e-14 53.0 0.2 2.2e-13 50.9 0.2 2.1 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 GAX28889.1 - 0.00021 21.4 0.0 0.00065 19.8 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fra10Ac1 PF09725.9 GAX28891.1 - 2.4e-35 121.3 0.0 3.7e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 ATP_bind_3 PF01171.20 GAX28892.1 - 1.3e-16 60.8 0.0 3.8e-16 59.4 0.0 1.8 1 1 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 GAX28892.1 - 0.0005 20.2 0.0 0.0042 17.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Ribosomal_S8e PF01201.22 GAX28893.1 - 4.8e-47 159.6 4.2 1.3e-46 158.2 4.2 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e Ribosomal_S6 PF01250.17 GAX28894.1 - 2.8e-15 56.3 0.0 3.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF719 PF05334.13 GAX28894.1 - 0.11 12.7 1.7 0.23 11.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Na_Ca_ex PF01699.24 GAX28895.1 - 2.3e-39 134.8 36.6 2.8e-20 72.8 18.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 GAX28896.1 - 1.5e-38 132.1 37.0 2.9e-19 69.5 19.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein HSF_DNA-bind PF00447.17 GAX28897.1 - 3.2e-13 50.1 0.0 5.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Microtub_bind PF13931.6 GAX28897.1 - 0.068 13.6 0.8 0.18 12.2 0.0 2.0 2 1 0 2 2 2 0 Kinesin-associated microtubule-binding HTH_Mga PF08280.11 GAX28897.1 - 0.074 13.1 0.9 6.1 6.9 0.1 2.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain PPR_2 PF13041.6 GAX28898.1 - 1.7e-06 28.1 0.0 1.5 9.0 0.0 5.3 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 GAX28898.1 - 0.00035 20.6 0.0 5.1 7.2 0.0 4.9 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAX28898.1 - 0.00073 19.0 0.7 0.18 11.2 0.1 3.3 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 GAX28898.1 - 0.0023 17.8 0.1 8.5 6.3 0.0 3.6 2 1 1 3 3 3 1 Mitochondrial ATPase expression TPR_19 PF14559.6 GAX28898.1 - 0.062 13.8 0.2 1.1e+02 3.4 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX28898.1 - 0.067 13.3 0.1 0.23 11.6 0.1 2.0 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Podoplanin PF05808.11 GAX28899.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Podoplanin DUF4514 PF14986.6 GAX28899.1 - 0.4 10.7 3.9 0.88 9.6 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) DEC-1_N PF04625.13 GAX28900.1 - 8.8 5.2 6.6 15 4.5 6.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-DNL PF05180.12 GAX28901.1 - 2.6e-23 81.7 0.1 5.2e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 GAX28901.1 - 0.031 14.0 0.4 0.09 12.5 0.4 1.8 1 0 0 1 1 1 0 CSL zinc finger Guanylate_cyc PF00211.20 GAX28902.1 - 9.9e-48 162.2 0.0 1.9e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NAD_binding_10 PF13460.6 GAX28902.1 - 4.7e-39 134.2 0.2 1.5e-38 132.5 0.2 2.0 1 0 0 1 1 1 1 NAD(P)H-binding PDEase_I PF00233.19 GAX28902.1 - 1.8e-31 109.7 0.5 3.9e-31 108.6 0.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase 3Beta_HSD PF01073.19 GAX28902.1 - 3.9e-06 26.1 0.2 7.1e-06 25.2 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 GAX28902.1 - 3.6e-05 23.3 1.8 6e-05 22.6 0.8 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 GAX28902.1 - 4.3e-05 23.2 1.5 0.00096 18.8 0.2 2.8 3 0 0 3 3 3 1 NmrA-like family Epimerase PF01370.21 GAX28902.1 - 0.00015 21.3 0.0 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAX28902.1 - 0.018 15.3 0.3 0.052 13.8 0.3 1.9 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 GAX28902.1 - 0.12 11.6 0.1 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein DUF2499 PF10693.9 GAX28903.1 - 1.9e-37 127.4 2.4 6.4e-37 125.7 2.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3593 PF12159.8 GAX28903.1 - 4.8e-31 106.6 4.7 1.4e-30 105.2 2.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3593) DUF5379 PF17350.2 GAX28903.1 - 0.021 15.1 0.3 5.6 7.3 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5379) TauD PF02668.16 GAX28904.1 - 3e-24 86.3 0.0 4.8e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAX28904.1 - 0.0068 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 CsiD Metallophos PF00149.28 GAX28905.1 - 7.3e-18 65.8 0.7 1.7e-17 64.6 0.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAX28905.1 - 4.6e-10 40.2 1.4 1.5e-09 38.6 1.4 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C RNA_pol_Rpb2_6 PF00562.28 GAX28906.1 - 1.7e-118 396.1 0.0 2.3e-118 395.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAX28906.1 - 1e-53 181.9 0.0 1.5e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 GAX28906.1 - 8.3e-32 109.5 0.1 2e-31 108.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GAX28906.1 - 7.9e-25 87.6 0.0 2.3e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 GAX28906.1 - 9.6e-24 83.5 0.2 2.5e-23 82.1 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 GAX28906.1 - 1.9e-21 76.0 0.1 8e-21 74.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 GAX28906.1 - 3.5e-14 53.1 0.1 1e-13 51.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Exostosin PF03016.15 GAX28907.1 - 7.2e-30 104.2 0.3 1.9e-29 102.8 0.3 1.6 1 1 0 1 1 1 1 Exostosin family TRAPP PF04051.16 GAX28908.1 - 9.3e-26 90.3 0.3 1.2e-25 89.9 0.3 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component HSCB_C PF07743.13 GAX28909.1 - 7e-17 61.7 5.7 1.7e-16 60.4 5.7 1.6 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 GAX28909.1 - 0.00012 22.1 0.1 0.00022 21.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DehI PF10778.9 GAX28909.1 - 0.015 15.4 0.2 0.025 14.7 0.1 1.5 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI RdRP PF05183.12 GAX28909.1 - 0.025 13.3 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Fungal_trans_2 PF11951.8 GAX28909.1 - 0.026 13.4 0.3 0.032 13.0 0.3 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain Baculo_PEP_C PF04513.12 GAX28909.1 - 0.14 12.2 1.2 0.2 11.7 1.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Metal_resist PF13801.6 GAX28909.1 - 2.8 8.2 8.4 7.3 6.8 5.0 2.3 2 0 0 2 2 2 0 Heavy-metal resistance Malate_synthase PF01274.22 GAX28910.1 - 7.6e-190 631.6 0.0 8.6e-190 631.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 GAX28910.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family adh_short PF00106.25 GAX28911.1 - 2.8e-32 111.7 1.3 3.8e-32 111.3 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28911.1 - 4.7e-19 68.9 0.1 7e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LacAB_rpiB PF02502.18 GAX28911.1 - 0.0033 17.4 0.6 0.0059 16.6 0.1 1.6 2 0 0 2 2 2 1 Ribose/Galactose Isomerase KR PF08659.10 GAX28911.1 - 0.12 12.3 0.2 0.25 11.2 0.2 1.6 1 1 0 1 1 1 0 KR domain Nnf1 PF03980.14 GAX28912.1 - 0.0011 19.3 8.2 0.0011 19.3 8.2 1.5 1 1 0 1 1 1 1 Nnf1 CorA PF01544.18 GAX28912.1 - 0.065 12.5 5.3 0.082 12.2 5.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein VIT1 PF01988.19 GAX28912.1 - 0.21 11.4 0.9 0.75 9.6 0.0 1.9 1 1 1 2 2 2 0 VIT family Phage_GP20 PF06810.11 GAX28912.1 - 0.44 10.3 14.2 0.17 11.7 2.6 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3708 PF12501.8 GAX28912.1 - 0.44 10.3 1.6 1.2 8.9 1.6 1.8 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF16 PF01519.16 GAX28912.1 - 0.47 11.0 6.0 1.8 9.1 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4640 PF15480.6 GAX28912.1 - 0.49 10.1 8.5 1.2 8.8 8.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4640) Sec20 PF03908.13 GAX28912.1 - 0.78 9.7 6.4 0.74 9.8 0.6 2.5 2 1 0 2 2 2 0 Sec20 Suppressor_APC PF11414.8 GAX28912.1 - 1.5 8.9 9.3 2.7 8.1 4.8 2.7 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF1068 PF06364.12 GAX28912.1 - 1.5 8.7 8.3 0.065 13.1 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) DUF1690 PF07956.11 GAX28912.1 - 1.5 9.2 12.1 0.06 13.8 3.0 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Csm1_N PF18504.1 GAX28912.1 - 1.8 9.0 14.3 0.96 9.8 5.2 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Cgr1 PF03879.14 GAX28912.1 - 2.6 8.4 14.8 0.15 12.5 6.3 2.0 2 0 0 2 2 2 0 Cgr1 family Goodbye PF17109.5 GAX28912.1 - 8.5 6.9 9.2 14 6.1 0.8 2.3 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain SNF2_N PF00176.23 GAX28913.1 - 6.3e-68 229.0 0.0 1.3e-67 228.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX28913.1 - 2.5e-10 40.7 0.0 6.7e-10 39.3 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28913.1 - 9.9e-09 35.4 0.0 3.2e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAX28913.1 - 9.9e-07 28.7 0.0 3e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 GAX28913.1 - 1.3e-06 28.3 4.9 3.9e-06 26.8 4.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX28913.1 - 4.6e-05 23.2 1.3 4.6e-05 23.2 1.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAX28913.1 - 5.1e-05 23.5 9.3 5.1e-05 23.5 9.3 2.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 GAX28913.1 - 6.3e-05 22.9 7.6 0.00062 19.7 8.2 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAX28913.1 - 0.00032 20.5 6.6 0.00032 20.5 6.6 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAX28913.1 - 0.00073 19.2 3.7 0.002 17.9 3.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAX28913.1 - 0.0043 16.9 13.3 0.0063 16.3 10.2 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX28913.1 - 0.01 15.7 7.7 0.01 15.7 7.7 2.9 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 Importin_rep_4 PF18808.1 GAX28913.1 - 0.3 11.4 4.2 2.9 8.2 4.0 2.5 2 0 0 2 2 2 0 Importin repeat FANCL_C PF11793.8 GAX28913.1 - 0.4 10.9 3.9 1.3 9.2 3.9 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain DUF2457 PF10446.9 GAX28913.1 - 2 7.5 10.2 12 4.9 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) zf-RING_6 PF14835.6 GAX28913.1 - 2.6 8.0 5.2 3.7 7.5 1.9 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein bZIP_1 PF00170.21 GAX28914.1 - 6.7e-10 38.9 17.2 1.2e-09 38.1 15.5 2.3 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAX28914.1 - 3.4e-06 27.0 13.0 9.3e-06 25.6 13.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAX28914.1 - 0.00011 22.7 11.5 0.0009 19.7 11.1 2.5 3 0 0 3 3 3 1 bZIP Maf transcription factor KRE1 PF17056.5 GAX28914.1 - 0.026 14.2 1.7 0.026 14.2 1.7 1.9 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 YgbB PF02542.16 GAX28915.1 - 7.1e-59 198.5 0.0 1e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 YgbB family adh_short PF00106.25 GAX28917.1 - 2.8e-19 69.4 0.1 2.1e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAX28917.1 - 6.7e-14 52.0 0.1 1.1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Spt4 PF06093.13 GAX28917.1 - 0.053 13.6 0.7 0.17 12.0 0.5 2.0 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger EF-hand_7 PF13499.6 GAX28918.1 - 1.3e-11 44.7 4.5 0.0031 17.9 0.0 5.4 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 GAX28918.1 - 7.1e-10 37.7 0.4 0.051 13.1 0.0 5.6 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 GAX28918.1 - 3.9e-09 35.7 0.1 0.83 9.7 0.0 5.5 6 0 0 6 6 6 3 EF-hand domain Nucleoporin2 PF04096.14 GAX28919.1 - 5e-36 124.1 0.0 9.6e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 GAX28919.1 - 5.8e-36 124.1 2.0 8.1e-36 123.6 2.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.6 GAX28919.1 - 2.3e-06 28.4 169.9 0.0075 17.1 17.6 8.4 2 2 5 7 7 7 4 Nucleoporin FG repeat region PHD PF00628.29 GAX28920.1 - 6.5e-17 61.2 33.9 8.6e-10 38.4 13.7 3.2 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 GAX28920.1 - 0.0018 17.8 3.2 0.0018 17.8 3.2 3.5 3 1 1 4 4 4 2 PHD-finger PhoD PF09423.10 GAX28921.1 - 5e-09 35.6 0.0 3.3e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.28 GAX28921.1 - 0.081 13.4 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase tRNA-synt_1b PF00579.25 GAX28922.1 - 2.1e-74 250.5 0.0 2.9e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 GAX28922.1 - 9.3e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 GAX28922.1 - 0.0013 18.6 0.0 0.0032 17.2 0.0 1.8 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain DERM PF14704.6 GAX28922.1 - 0.082 13.4 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Dermatopontin MmoB_DmpM PF02406.17 GAX28923.1 - 0.062 13.5 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 MmoB/DmpM family HAT_KAT11 PF08214.11 GAX28924.1 - 9.4e-33 113.9 0.0 9.4e-33 113.9 0.0 2.5 2 0 0 2 2 2 1 Histone acetylation protein zf-TAZ PF02135.16 GAX28924.1 - 1.8e-25 89.2 36.8 2.6e-16 59.9 14.6 4.9 5 1 0 5 5 5 2 TAZ zinc finger Bromodomain PF00439.25 GAX28924.1 - 9.5e-24 83.3 0.1 1.4e-22 79.5 0.0 2.6 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 GAX28924.1 - 3.2e-08 33.3 6.6 3.2e-08 33.3 6.6 3.9 4 1 1 5 5 5 1 PHD-finger KIX_2 PF16987.5 GAX28924.1 - 1.9e-07 31.0 0.8 1.9e-07 31.0 0.8 2.7 3 0 0 3 3 3 1 KIX domain ZZ PF00569.17 GAX28924.1 - 1.9e-06 27.6 6.3 1.9e-06 27.6 6.3 3.5 4 0 0 4 4 4 1 Zinc finger, ZZ type DUF902 PF06001.13 GAX28924.1 - 0.05 14.1 3.5 0.14 12.7 3.5 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) Pullulanase_Ins PF18494.1 GAX28926.1 - 0.11 12.9 2.2 0.59 10.6 0.3 2.7 2 0 0 2 2 2 0 Pullulanase Ins domain DUF5304 PF17230.2 GAX28926.1 - 0.35 11.1 5.1 4.3 7.6 0.7 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5304) CDC37_N PF03234.14 GAX28926.1 - 4.2 8.3 8.2 19 6.1 2.2 3.2 2 1 1 3 3 3 0 Cdc37 N terminal kinase binding TPR_MLP1_2 PF07926.12 GAX28927.1 - 2.5e-15 56.7 24.8 2.5e-15 56.7 24.8 16.2 7 4 6 16 16 16 3 TPR/MLP1/MLP2-like protein ZapB PF06005.12 GAX28927.1 - 0.00042 20.7 5.7 0.00042 20.7 5.7 22.0 9 6 9 18 18 18 3 Cell division protein ZapB DUF3800 PF12686.7 GAX28927.1 - 2.7 8.6 6.9 5.2e+03 -2.0 6.9 5.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) PX PF00787.24 GAX28928.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 PX domain Tim17 PF02466.19 GAX28929.1 - 1.6e-11 44.6 5.9 2.9e-11 43.7 5.9 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HA2 PF04408.23 GAX28930.1 - 3.8e-18 65.8 0.0 1e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAX28930.1 - 1.8e-16 60.3 0.0 5.3e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAX28930.1 - 2.4e-12 47.2 0.0 1.9e-11 44.3 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAX28930.1 - 1.3e-07 31.6 0.1 4e-07 30.0 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GAX28930.1 - 0.046 14.1 0.2 0.13 12.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain UPF0176_N PF17773.1 GAX28931.1 - 2.1e-13 50.4 0.0 4.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAX28931.1 - 4.8e-09 36.5 4.3 4.8e-09 36.5 4.3 2.2 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 GAX28931.1 - 0.037 14.6 0.0 0.099 13.2 0.0 1.8 1 1 0 1 1 1 0 Rhodanese-like domain TAFII55_N PF04658.13 GAX28932.1 - 2.4e-19 69.6 0.6 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 1 TAFII55 protein conserved region Ferlin_C PF16165.5 GAX28932.1 - 0.42 10.5 4.1 0.9 9.5 4.1 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Abhydrolase_1 PF00561.20 GAX28933.1 - 3.6e-17 62.9 0.0 7.8e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAX28933.1 - 3.8e-16 60.4 1.5 4.9e-16 60.0 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX28933.1 - 2.4e-12 46.6 0.0 3.2e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAX28933.1 - 1.1e-05 25.6 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Lipase PF00151.19 GAX28933.1 - 0.00046 19.6 0.0 0.00062 19.2 0.0 1.1 1 0 0 1 1 1 1 Lipase DUF1100 PF06500.11 GAX28933.1 - 0.00054 18.9 0.0 0.00071 18.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Lipase_3 PF01764.25 GAX28933.1 - 0.00067 19.5 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.13 GAX28933.1 - 0.0039 16.9 0.0 0.82 9.3 0.0 2.2 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DUF676 PF05057.14 GAX28933.1 - 0.0085 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAX28933.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 GAX28933.1 - 0.022 14.6 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LIDHydrolase PF10230.9 GAX28933.1 - 0.023 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase BAAT_C PF08840.11 GAX28933.1 - 0.033 14.1 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 GAX28933.1 - 0.04 13.2 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 GAX28933.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 GAX28933.1 - 0.049 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ndr PF03096.14 GAX28933.1 - 0.069 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF3530 PF12048.8 GAX28933.1 - 0.07 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF2974 PF11187.8 GAX28933.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 GAX28933.1 - 0.09 12.4 0.1 0.26 10.9 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Pkinase PF00069.25 GAX28934.1 - 2.2e-57 194.4 0.0 3.4e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 GAX28934.1 - 5.5e-34 116.1 0.0 4.4e-17 61.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GAX28934.1 - 2.2e-27 96.0 0.0 3.1e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX28934.1 - 9.3e-11 42.0 3.0 9.7e-05 22.8 0.2 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAX28934.1 - 7.8e-09 35.3 0.8 0.00013 21.8 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair APH PF01636.23 GAX28934.1 - 2.3e-07 31.0 0.0 0.0063 16.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family EF-hand_1 PF00036.32 GAX28934.1 - 5.4e-07 28.7 1.8 6.8e-05 22.1 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 GAX28934.1 - 1.1e-06 28.1 6.4 0.00091 19.0 0.0 4.8 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.6 GAX28934.1 - 3.7e-05 23.0 0.1 0.00013 21.3 0.1 2.0 1 0 0 1 1 1 1 EF hand Kinase-like PF14531.6 GAX28934.1 - 4.9e-05 22.8 0.0 0.00046 19.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAX28934.1 - 4.9e-05 22.8 0.0 0.00019 20.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAX28934.1 - 0.014 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Alba PF01918.21 GAX28935.1 - 1.3e-18 66.6 0.0 1.9e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 GAX28935.1 - 9.9e-07 28.8 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Glyco_trans_1_4 PF13692.6 GAX28936.1 - 2.8e-05 24.6 0.0 0.0014 19.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAX28936.1 - 0.00014 21.4 0.0 0.021 14.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAX28936.1 - 0.011 16.1 0.0 0.036 14.5 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 TIP41 PF04176.13 GAX28937.1 - 6.1e-42 143.0 0.0 1.4e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 TIP41-like family Glutaredoxin PF00462.24 GAX28937.1 - 0.004 17.3 0.1 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin S6PP_C PF08472.10 GAX28937.1 - 0.013 15.4 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal 2OG-FeII_Oxy_3 PF13640.6 GAX28938.1 - 1.3e-14 54.9 0.2 2e-14 54.2 0.2 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 GAX28938.1 - 0.00034 21.1 6.2 0.00083 19.8 6.2 1.7 1 0 0 1 1 1 1 ShK domain-like MTS PF05175.14 GAX28939.1 - 1.2e-12 47.7 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAX28939.1 - 4.9e-10 40.0 0.0 1.7e-08 35.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GAX28939.1 - 3.8e-09 36.4 0.1 3.9e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAX28939.1 - 1.9e-08 34.2 0.0 5e-08 32.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmC_N PF17827.1 GAX28939.1 - 6.8e-07 29.8 1.5 1.5e-06 28.7 0.4 2.2 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_12 PF08242.12 GAX28939.1 - 7.3e-05 23.4 0.0 0.00019 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAX28939.1 - 0.00015 21.8 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX28939.1 - 0.00016 22.2 0.0 0.0018 18.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 GAX28939.1 - 0.00027 20.7 0.4 0.00094 18.9 0.4 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.9 GAX28939.1 - 0.00033 20.5 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 GAX28939.1 - 0.00036 20.2 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 GAX28939.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 GAX28939.1 - 0.0039 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_2 PF00891.18 GAX28939.1 - 0.0039 16.5 0.0 0.0075 15.6 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 GAX28939.1 - 0.0039 17.1 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 GAX28939.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_15 PF09445.10 GAX28939.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 GAX28939.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase HIP1_clath_bdg PF16515.5 GAX28940.1 - 0.7 10.5 5.8 11 6.8 0.3 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MIR PF02815.19 GAX28942.1 - 5.4e-08 32.9 0.0 1.5e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 MIR domain DUF3546 PF12066.8 GAX28943.1 - 1.5e-07 31.5 1.6 1.5e-07 31.5 1.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 GAX28943.1 - 0.0055 17.1 0.3 0.012 16.0 0.3 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 ASF1_hist_chap PF04729.13 GAX28944.1 - 3.8e-64 215.3 0.0 4.7e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Bac_surface_Ag PF01103.23 GAX28945.1 - 6e-22 78.6 0.2 1.1e-21 77.7 0.2 1.4 1 0 0 1 1 1 1 Surface antigen Med4 PF10018.9 GAX28945.1 - 0.33 10.6 1.7 0.51 10.0 1.7 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Dynamin_N PF00350.23 GAX28946.1 - 1.3e-11 44.9 0.2 4e-11 43.2 0.2 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAX28946.1 - 2.3e-11 43.8 0.1 8.1e-11 42.0 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX28946.1 - 2.5e-09 37.0 4.4 1.9e-08 34.1 4.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAX28946.1 - 1.7e-05 24.3 1.5 4e-05 23.1 0.5 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAX28946.1 - 2.5e-05 23.8 1.1 0.0094 15.4 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAX28946.1 - 0.00019 21.6 3.7 0.0019 18.4 0.2 3.2 4 0 0 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 GAX28946.1 - 0.00028 20.5 0.7 0.62 9.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX28946.1 - 0.0036 17.2 2.5 2.6 7.9 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase Ras PF00071.22 GAX28946.1 - 0.0044 16.6 1.0 0.036 13.7 0.1 2.5 2 0 0 2 2 2 1 Ras family NOG1 PF06858.14 GAX28946.1 - 0.0057 16.4 0.7 0.029 14.2 0.5 2.3 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) cobW PF02492.19 GAX28946.1 - 0.007 16.0 1.3 0.17 11.5 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 GAX28946.1 - 0.1 12.8 0.1 0.4 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Got1 PF04178.12 GAX28947.1 - 2.2e-25 89.2 6.3 3.9e-25 88.5 5.7 1.6 1 1 1 2 2 2 1 Got1/Sft2-like family PsaL PF02605.15 GAX28948.1 - 0.066 12.9 1.1 0.63 9.7 1.1 2.1 1 1 0 1 1 1 0 Photosystem I reaction centre subunit XI CrgA PF06781.12 GAX28948.1 - 0.33 11.0 1.3 1.7 8.7 0.0 2.2 2 1 0 2 2 2 0 Cell division protein CrgA MNHE PF01899.16 GAX28948.1 - 3.9 7.2 8.5 5.8 6.7 1.1 2.1 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF21 PF01595.20 GAX28949.1 - 4.5e-27 94.9 2.2 6.5e-27 94.4 1.0 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAX28949.1 - 0.0027 18.1 0.6 0.04 14.4 0.1 3.1 2 1 0 2 2 2 1 CBS domain ATP-synt_C PF00137.21 GAX28949.1 - 0.012 16.0 0.1 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 ATP synthase subunit C Mntp PF02659.15 GAX28949.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative manganese efflux pump Cytadhesin_P30 PF07271.11 GAX28949.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 ABC_membrane_2 PF06472.15 GAX28950.1 - 1.9e-62 211.1 2.5 2.6e-62 210.7 2.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAX28950.1 - 1.8e-19 70.6 0.0 3.6e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 GAX28950.1 - 1.2e-15 57.8 3.1 5.1e-15 55.7 3.1 1.8 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_membrane PF00664.23 GAX28950.1 - 7e-05 22.6 1.9 0.00021 21.0 1.9 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 GAX28950.1 - 0.00014 21.5 0.1 0.00038 20.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAX28950.1 - 0.00017 22.0 0.1 0.00055 20.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAX28950.1 - 0.00027 20.9 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GAX28950.1 - 0.00063 20.3 0.1 0.0018 18.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAX28950.1 - 0.00071 19.5 0.0 0.0044 17.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 GAX28950.1 - 0.0013 18.5 0.0 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAX28950.1 - 0.0018 18.5 0.2 0.056 13.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAX28950.1 - 0.0029 16.8 0.2 0.0059 15.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_21 PF13304.6 GAX28950.1 - 0.0036 17.2 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAX28950.1 - 0.0052 16.3 0.3 1.1 8.7 0.1 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 GAX28950.1 - 0.02 14.6 0.1 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 GAX28950.1 - 0.031 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 GAX28950.1 - 0.04 14.0 0.2 0.085 12.9 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_27 PF13514.6 GAX28950.1 - 0.091 12.3 0.1 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 GAX28950.1 - 0.23 10.5 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain MTBP_N PF14918.6 GAX28951.1 - 0.0072 15.8 0.5 0.0097 15.4 0.3 1.2 1 1 0 1 1 1 1 MDM2-binding Lysyl_oxidase PF01186.17 GAX28953.1 - 4.6e-41 140.7 0.0 9.1e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 Lysyl oxidase Pkinase PF00069.25 GAX28954.1 - 2.2e-64 217.4 0.0 3.7e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX28954.1 - 4.8e-31 108.0 0.0 8.1e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GAX28954.1 - 3.7e-12 46.5 1.8 1.4e-05 25.5 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAX28954.1 - 9.1e-10 37.7 1.0 0.0023 17.7 0.3 3.7 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 GAX28954.1 - 1.9e-09 36.4 1.7 0.0022 17.4 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAX28954.1 - 3.7e-05 23.5 3.4 0.058 13.3 0.3 3.9 1 1 2 3 3 3 2 EF-hand domain pair Pkinase_fungal PF17667.1 GAX28954.1 - 4.9e-05 22.3 0.1 0.0011 17.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_5 PF13202.6 GAX28954.1 - 6.3e-05 22.3 0.3 0.028 13.9 0.0 2.7 2 0 0 2 2 2 2 EF hand Kdo PF06293.14 GAX28954.1 - 0.00014 21.3 0.9 0.00025 20.5 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX28954.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAX28954.1 - 0.0059 16.0 0.1 0.086 12.1 0.1 2.6 1 1 1 2 2 2 1 Kinase-like Sigma70_r1_1 PF03979.14 GAX28954.1 - 0.09 12.8 0.3 1.4 9.0 0.0 3.0 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 PT PF04886.12 GAX28955.1 - 1.3e-33 114.2 439.7 0.0011 18.5 14.2 23.7 5 2 16 21 21 21 19 PT repeat Yae1_N PF09811.9 GAX28956.1 - 0.52 10.1 6.6 5.6 6.8 0.8 3.8 2 2 0 2 2 2 0 Essential protein Yae1, N terminal PT PF04886.12 GAX28957.1 - 3.4e-05 23.3 36.9 4.3 7.0 1.2 3.9 2 1 0 2 2 2 2 PT repeat ECH_1 PF00378.20 GAX28958.1 - 1.8e-81 273.2 0.8 2.2e-81 272.8 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAX28958.1 - 1.6e-38 133.0 2.6 5.5e-34 118.1 0.5 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ABC2_membrane PF01061.24 GAX28959.1 - 2.6e-31 108.7 4.0 3.7e-31 108.2 4.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAX28959.1 - 2.5e-22 79.8 0.0 9e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 GAX28959.1 - 2.2e-06 27.3 0.2 0.0094 15.4 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX28959.1 - 4.3e-06 26.8 0.0 0.0087 15.9 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAX28959.1 - 6.5e-05 23.4 0.2 0.00076 19.9 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 GAX28959.1 - 0.0045 16.6 0.1 0.5 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAX28959.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 GAX28959.1 - 0.0089 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 GAX28959.1 - 0.0091 16.3 0.1 0.054 13.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 GAX28959.1 - 0.034 13.9 0.2 0.09 12.5 0.2 1.7 1 0 0 1 1 1 0 Cytidylate kinase AAA_29 PF13555.6 GAX28959.1 - 0.055 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 GAX28959.1 - 0.057 13.2 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 GAX28959.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 GAX28959.1 - 0.084 13.1 0.1 0.34 11.2 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 GAX28959.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAX28959.1 - 0.13 12.1 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 GAX28959.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase LRR_6 PF13516.6 GAX28960.1 - 4.2e-08 32.6 1.4 2.8e-05 23.8 0.4 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 GAX28960.1 - 0.12 12.8 3.1 0.44 11.0 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX28960.1 - 0.19 11.5 2.3 0.4 10.5 0.2 2.8 3 1 0 3 3 3 0 Leucine rich repeat 2OG-FeII_Oxy PF03171.20 GAX28961.1 - 2.8e-06 27.7 0.0 5.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF563 PF04577.14 GAX28962.1 - 1.1e-15 58.4 0.1 1.5e-15 57.9 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DUF2407 PF10302.9 GAX28963.1 - 2.2e-05 24.9 0.1 2.2e-05 24.9 0.1 2.8 2 1 1 3 3 3 1 DUF2407 ubiquitin-like domain Blt1 PF12754.7 GAX28963.1 - 0.0048 17.2 0.2 0.011 16.0 0.2 1.6 1 0 0 1 1 1 1 Blt1 N-terminal domain ubiquitin PF00240.23 GAX28963.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family GIDA_assoc PF13932.6 GAX28963.1 - 0.019 15.2 1.5 0.019 15.2 1.5 1.8 2 0 0 2 2 2 0 GidA associated domain DDHD PF02862.17 GAX28963.1 - 0.44 10.7 3.0 3.8 7.6 1.6 2.2 2 0 0 2 2 2 0 DDHD domain Glyco_tranf_2_4 PF13704.6 GAX28964.1 - 0.00013 22.4 0.3 0.00038 20.9 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Nucleotid_trans PF03407.16 GAX28965.1 - 9.1e-23 81.3 0.4 1.4e-22 80.8 0.4 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Hexapep PF00132.24 GAX28966.1 - 5.8e-07 29.0 9.6 0.0024 17.6 0.2 4.1 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAX28966.1 - 0.0018 17.3 0.2 0.0026 16.8 0.1 1.3 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 GAX28966.1 - 0.011 15.5 8.6 0.068 12.9 2.5 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase XPA_C PF05181.12 GAX28967.1 - 3.8e-09 36.4 0.1 1.6e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 XPA protein C-terminus Macoilin PF09726.9 GAX28967.1 - 0.068 11.7 6.5 0.08 11.5 6.5 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 GAX28967.1 - 3 6.5 9.1 2.9 6.6 9.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 GAX28967.1 - 7.2 4.4 7.0 9.2 4.0 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 GAX28967.1 - 8.9 5.4 5.1 8.4 5.5 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Complex1_LYR PF05347.15 GAX28968.1 - 1.8e-09 37.5 0.1 2.3e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAX28968.1 - 0.0089 16.8 0.9 0.0095 16.7 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Prenyltrans PF00432.21 GAX28969.1 - 1.5e-37 127.0 15.8 7e-10 38.5 1.4 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat GRASP55_65 PF04495.14 GAX28970.1 - 2.6e-60 202.7 0.0 2.8e-43 147.5 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 GAX28970.1 - 5.2e-07 29.4 0.0 0.027 14.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 GAX28970.1 - 3.3e-06 27.3 0.0 0.004 17.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain GREB1 PF15782.5 GAX28970.1 - 0.26 8.4 1.1 0.33 8.0 1.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glutaredoxin PF00462.24 GAX28971.1 - 9.2e-21 73.8 0.0 1.2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 GAX28971.1 - 0.0098 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.6 GAX28971.1 - 0.023 15.1 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 GAX28971.1 - 0.039 14.4 0.3 0.076 13.5 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 GAX28971.1 - 0.057 13.2 1.9 1.3 8.7 0.2 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N_2 PF13409.6 GAX28971.1 - 0.076 13.3 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.6 GAX28971.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin RRM_1 PF00076.22 GAX28972.1 - 3.2e-38 129.4 0.0 3.4e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAX28972.1 - 7e-07 28.9 0.0 0.011 15.3 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 GAX28972.1 - 0.003 17.2 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_7 PF16367.5 GAX28972.1 - 0.0036 17.4 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif Nucleotid_trans PF03407.16 GAX28973.1 - 2.3e-27 96.4 0.2 3.2e-27 95.9 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TRM PF02005.16 GAX28974.1 - 3.7e-113 378.5 0.0 4.6e-113 378.2 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 GAX28974.1 - 0.00044 20.1 0.0 0.00067 19.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 GAX28974.1 - 0.085 12.8 0.3 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAX28974.1 - 0.086 13.6 0.1 0.36 11.6 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Adeno_GP19K PF04881.13 GAX28974.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus GP19K MTS PF05175.14 GAX28974.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Asp PF00026.23 GAX28975.1 - 7.1e-100 334.5 0.7 8.5e-100 334.2 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAX28975.1 - 4.8e-15 56.2 0.8 6.6e-13 49.3 0.8 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAX28975.1 - 0.037 14.7 0.2 21 5.8 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 GAX28975.1 - 0.039 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Adaptin_N PF01602.20 GAX28976.1 - 4e-79 266.5 0.5 5.2e-79 266.2 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 GAX28976.1 - 5.3e-16 58.8 0.1 1.2e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 GAX28976.1 - 2.7e-08 34.0 0.9 1.5e-07 31.6 0.1 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAX28976.1 - 1.5e-05 25.3 2.4 1.3 9.6 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 GAX28976.1 - 0.0067 16.6 1.8 0.69 10.3 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat TIP120 PF08623.10 GAX28976.1 - 0.14 11.9 0.4 3.3 7.5 0.1 2.6 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) zf-C2H2 PF00096.26 GAX28977.1 - 4.1e-07 30.1 8.8 1.1e-05 25.6 2.0 5.9 8 0 0 8 8 7 2 Zinc finger, C2H2 type zf-met PF12874.7 GAX28977.1 - 3e-06 27.4 7.3 0.0083 16.5 1.3 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 GAX28977.1 - 3.1e-05 24.2 4.6 0.013 15.8 0.7 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 GAX28977.1 - 0.0003 21.4 9.0 0.0074 17.0 1.3 6.2 8 0 0 8 8 7 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 GAX28977.1 - 0.00052 20.1 1.2 0.00052 20.1 1.2 5.5 5 2 0 5 5 5 1 Zinc ribbon domain Stc1 PF12898.7 GAX28977.1 - 0.002 18.6 22.7 0.034 14.7 0.2 3.7 2 1 1 3 3 3 2 Stc1 domain zf-C2H2_6 PF13912.6 GAX28977.1 - 0.0025 17.8 0.7 0.0025 17.8 0.7 4.7 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAX28977.1 - 0.007 16.6 11.7 0.012 15.9 0.3 3.9 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 GAX28977.1 - 0.059 13.8 0.1 0.059 13.8 0.1 4.9 6 0 0 6 6 5 0 Zinc-finger double domain zf-C2HE PF16278.5 GAX28977.1 - 1.5 9.3 10.1 0.81 10.2 2.1 3.1 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 GAX28977.1 - 1.7 9.0 19.3 0.6 10.5 2.3 3.8 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 GAX28977.1 - 3.4 7.4 8.7 10 5.9 0.0 3.5 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain TauE PF01925.19 GAX28978.1 - 7.8e-28 97.7 26.6 4e-11 43.0 16.2 3.2 2 1 1 3 3 3 3 Sulfite exporter TauE/SafE MHC2-interact PF09307.10 GAX28978.1 - 0.046 13.7 1.8 5.3 7.1 0.1 2.4 2 0 0 2 2 2 0 CLIP, MHC2 interacting Prefoldin_2 PF01920.20 GAX28979.1 - 4e-19 68.5 6.5 4.7e-19 68.3 6.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit SPAM PF02090.15 GAX28979.1 - 0.00016 21.5 5.4 0.0037 17.1 1.1 2.1 2 0 0 2 2 2 1 Salmonella surface presentation of antigen gene type M protein Prefoldin PF02996.17 GAX28979.1 - 0.00086 19.2 8.0 0.14 12.1 8.0 2.1 1 1 0 1 1 1 1 Prefoldin subunit DASH_Spc19 PF08287.11 GAX28979.1 - 0.002 18.1 7.3 0.023 14.6 2.3 2.1 2 0 0 2 2 2 1 Spc19 HALZ PF02183.18 GAX28979.1 - 0.0041 17.3 10.9 0.044 14.0 2.3 2.3 2 0 0 2 2 2 2 Homeobox associated leucine zipper DivIC PF04977.15 GAX28979.1 - 0.0049 16.6 12.8 0.051 13.4 1.4 2.3 2 0 0 2 2 2 2 Septum formation initiator DUF4140 PF13600.6 GAX28979.1 - 0.0077 16.6 7.0 0.87 10.1 2.1 2.1 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) Not3 PF04065.15 GAX28979.1 - 0.0088 15.5 3.1 0.22 10.9 0.1 2.0 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component JIP_LZII PF16471.5 GAX28979.1 - 0.013 15.7 4.0 1.2 9.3 0.7 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II FlaC_arch PF05377.11 GAX28979.1 - 0.024 15.0 3.3 0.23 11.9 0.5 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FTA4 PF13093.6 GAX28979.1 - 0.026 14.4 12.5 0.071 13.0 2.1 2.0 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4200 PF13863.6 GAX28979.1 - 0.047 14.1 7.8 1.7 9.0 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FliD_N PF02465.18 GAX28979.1 - 0.051 14.3 4.3 6.1 7.6 1.6 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Snapin_Pallidin PF14712.6 GAX28979.1 - 0.12 12.8 5.2 1.4 9.4 0.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin APG6_N PF17675.1 GAX28979.1 - 0.14 12.7 10.5 0.46 11.0 1.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Fungal_TACC PF12709.7 GAX28979.1 - 0.15 12.6 4.9 4.8 7.7 0.2 2.2 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins GIT_CC PF16559.5 GAX28979.1 - 0.15 11.9 6.2 1.9 8.4 0.6 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FOXP-CC PF16159.5 GAX28979.1 - 0.29 11.8 3.7 0.85 10.3 0.3 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF1664 PF07889.12 GAX28979.1 - 0.3 11.1 3.6 2.1 8.4 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 GAX28979.1 - 0.33 11.2 8.4 3.6 7.9 8.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 GAX28979.1 - 0.34 11.3 10.2 1.1 9.7 10.2 1.7 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_1 PF00170.21 GAX28979.1 - 0.39 10.8 8.6 0.78 9.9 1.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor Fzo_mitofusin PF04799.13 GAX28979.1 - 0.41 10.2 3.9 0.29 10.7 0.5 1.9 2 0 0 2 2 2 0 fzo-like conserved region NPV_P10 PF05531.12 GAX28979.1 - 0.44 11.0 3.0 18 5.9 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_lid_9 PF17871.1 GAX28979.1 - 0.48 10.4 4.8 4.1 7.4 0.9 2.1 2 0 0 2 2 2 0 AAA lid domain FUSC PF04632.12 GAX28979.1 - 0.48 8.9 1.3 0.52 8.8 1.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PI3K_P85_iSH2 PF16454.5 GAX28979.1 - 0.49 10.0 12.6 0.081 12.5 3.4 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Nnf1 PF03980.14 GAX28979.1 - 0.6 10.5 8.9 1.8 9.0 1.4 2.1 2 0 0 2 2 2 0 Nnf1 ZapB PF06005.12 GAX28979.1 - 0.61 10.6 10.1 1.1 9.7 1.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DUF4446 PF14584.6 GAX28979.1 - 1 9.3 5.8 1.6 8.7 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) bZIP_Maf PF03131.17 GAX28979.1 - 1 9.9 12.4 3.6 8.2 2.4 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor UPF0449 PF15136.6 GAX28979.1 - 1.1 9.8 7.8 0.72 10.3 1.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF5595 PF18077.1 GAX28979.1 - 1.2 9.2 8.0 3 8.0 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Synaptobrevin PF00957.21 GAX28979.1 - 1.4 8.8 4.8 0.5 10.2 1.2 1.9 2 0 0 2 2 2 0 Synaptobrevin FapA PF03961.13 GAX28979.1 - 1.6 7.3 6.0 3.8 6.0 5.7 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 GAX28979.1 - 1.9 9.1 7.4 9.5 6.9 0.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 GAX28979.1 - 2.2 8.4 11.6 2.1 8.4 2.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2205 PF10224.9 GAX28979.1 - 2.4 8.2 9.0 1.1 9.3 0.9 2.2 2 0 0 2 2 2 0 Short coiled-coil protein Spc7 PF08317.11 GAX28979.1 - 2.9 6.7 12.1 44 2.8 12.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 GAX28979.1 - 2.9 8.2 10.5 1.1 9.6 2.8 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HemX PF04375.14 GAX28979.1 - 3 7.0 11.0 0.87 8.8 1.9 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase MctB PF11382.8 GAX28979.1 - 3.8 7.1 6.1 15 5.1 0.5 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB HAUS6_N PF14661.6 GAX28979.1 - 4 6.9 9.7 43 3.6 9.7 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4337 PF14235.6 GAX28979.1 - 6.6 6.8 7.1 2.8 8.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF4407 PF14362.6 GAX28979.1 - 7 5.9 12.0 1.2e+02 1.9 12.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 GAX28979.1 - 9.3 6.5 11.1 4.5e+02 1.1 11.1 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PMSR PF01625.21 GAX28980.1 - 5.5e-09 36.4 2.0 1.6e-08 34.8 2.0 1.7 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase SDA1 PF05285.12 GAX28981.1 - 9.8 5.5 54.6 0.38 10.1 18.6 3.3 3 0 0 3 3 3 0 SDA1 PPTA PF01239.22 GAX28982.1 - 3.8e-26 90.0 15.0 2.3e-08 33.5 0.1 6.2 5 1 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat FAO_M PF16350.5 GAX28982.1 - 0.62 10.4 2.3 0.94 9.9 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase central domain DnaJ PF00226.31 GAX28983.1 - 3.1e-17 62.4 0.2 6.8e-17 61.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain LOR PF04525.12 GAX28985.1 - 0.047 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 LURP-one-related Peptidase_M6 PF05547.11 GAX28988.1 - 2.1e-05 23.1 3.2 0.00029 19.3 3.2 2.3 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 PPR_2 PF13041.6 GAX28990.1 - 4.9e-53 177.1 0.1 2.7e-11 43.5 0.0 11.5 7 3 5 12 12 11 9 PPR repeat family PPR_3 PF13812.6 GAX28990.1 - 1.4e-40 137.2 0.0 4.3e-07 29.9 0.0 9.8 8 2 3 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.20 GAX28990.1 - 9.5e-40 132.1 1.8 0.00086 19.4 0.0 12.7 13 0 0 13 13 12 10 PPR repeat PPR_long PF17177.4 GAX28990.1 - 1.7e-27 96.2 4.7 2.1e-08 33.8 0.5 4.6 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAX28990.1 - 1.3e-23 82.3 0.0 0.0044 16.7 0.0 11.8 13 0 0 13 13 13 4 PPR repeat TPR_14 PF13428.6 GAX28990.1 - 6.3e-08 32.8 28.2 0.47 11.4 0.3 10.4 7 3 4 11 11 11 2 Tetratricopeptide repeat COX5A PF02284.16 GAX28990.1 - 1.4e-06 28.2 0.1 3.8 7.6 0.0 4.6 4 0 0 4 4 4 3 Cytochrome c oxidase subunit Va TPR_5 PF12688.7 GAX28990.1 - 0.0035 17.6 2.0 0.08 13.2 0.6 3.5 3 1 0 4 4 4 1 Tetratrico peptide repeat TPR_7 PF13176.6 GAX28990.1 - 0.011 15.7 0.4 4.3 7.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAX28990.1 - 0.065 13.9 10.0 7.1 7.5 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3368 PF11848.8 GAX28990.1 - 0.13 12.0 0.3 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) TPR_16 PF13432.6 GAX28990.1 - 0.31 11.7 15.7 2 9.1 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAX28990.1 - 0.81 10.5 26.7 0.82 10.5 1.2 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat Neuroparsin PF07327.11 GAX28991.1 - 3.1 8.3 10.9 2.9 8.4 9.2 1.9 1 1 0 1 1 1 0 Neuroparsin MMR_HSR1 PF01926.23 GAX28993.1 - 9.3e-42 141.7 0.0 9.6e-22 77.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 GAX28993.1 - 1.1e-20 73.7 0.2 2.9e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 GAX28993.1 - 4.8e-19 68.4 0.0 3.6e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 GAX28993.1 - 6.8e-14 52.1 0.0 8.3e-08 32.5 0.0 4.1 3 1 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAX28993.1 - 7.8e-14 51.7 0.1 9e-07 28.6 0.1 4.6 4 1 0 4 4 4 2 Elongation factor Tu GTP binding domain Arf PF00025.21 GAX28993.1 - 2.2e-09 37.0 0.1 2.4e-05 23.9 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAX28993.1 - 2.3e-08 34.1 0.2 0.087 12.7 0.0 4.0 3 1 1 4 4 4 2 RsgA GTPase Dynamin_N PF00350.23 GAX28993.1 - 4.1e-08 33.5 0.3 0.022 14.8 0.1 3.7 2 1 1 3 3 3 3 Dynamin family Ras PF00071.22 GAX28993.1 - 2.9e-07 30.2 0.0 0.0018 17.9 0.0 3.0 3 1 0 3 3 3 2 Ras family ABC_tran PF00005.27 GAX28993.1 - 1.1e-05 26.0 0.0 0.042 14.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AIG1 PF04548.16 GAX28993.1 - 2.5e-05 23.7 0.0 0.00039 19.8 0.0 2.7 2 2 0 2 2 2 1 AIG1 family Septin PF00735.18 GAX28993.1 - 3.7e-05 23.2 0.0 0.31 10.3 0.0 3.2 3 0 0 3 3 3 1 Septin AAA_16 PF13191.6 GAX28993.1 - 0.00012 22.5 1.3 0.95 9.8 0.2 3.4 2 2 0 2 2 2 2 AAA ATPase domain SRPRB PF09439.10 GAX28993.1 - 0.00014 21.4 0.0 0.0013 18.2 0.0 2.4 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAX28993.1 - 0.00026 20.8 0.0 0.64 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAX28993.1 - 0.00038 21.0 0.1 0.84 10.2 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GAX28993.1 - 0.00045 20.5 0.2 0.47 10.7 0.0 3.2 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX28993.1 - 0.00076 19.7 1.0 0.07 13.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAX28993.1 - 0.0012 19.2 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 GAX28993.1 - 0.004 16.9 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.22 GAX28993.1 - 0.0041 16.3 0.0 2.5 7.2 0.0 3.2 2 1 1 3 3 3 1 NB-ARC domain cobW PF02492.19 GAX28993.1 - 0.0046 16.6 0.8 3.2 7.3 0.1 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 GAX28993.1 - 0.0047 16.4 0.0 2 7.8 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein MeaB PF03308.16 GAX28993.1 - 0.0083 15.1 0.5 5.9 5.8 0.0 3.7 3 1 1 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 GAX28993.1 - 0.013 15.8 0.4 1.3 9.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 GAX28993.1 - 0.018 15.0 0.1 0.18 11.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 GAX28993.1 - 0.022 14.1 0.0 1.1 8.5 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.29 GAX28993.1 - 0.024 15.1 0.5 7.3 7.0 0.0 3.5 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) OB_NTP_bind PF07717.16 GAX28993.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold NTPase_1 PF03266.15 GAX28993.1 - 0.055 13.4 0.1 15 5.5 0.0 2.7 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 GAX28993.1 - 0.073 12.8 0.0 20 4.9 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Nuc_deoxyri_tr2 PF15891.5 GAX28993.1 - 2.6 8.4 5.0 10 6.4 0.6 2.9 3 0 0 3 3 2 0 Nucleoside 2-deoxyribosyltransferase like Pkinase_Tyr PF07714.17 GAX28995.1 - 2.9e-34 118.5 0.0 4.1e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAX28995.1 - 4e-34 118.2 0.0 2.7e-33 115.5 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain APH PF01636.23 GAX28995.1 - 0.0057 16.6 0.2 0.011 15.7 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DEAD PF00270.29 GAX28996.1 - 2.1e-19 70.0 0.0 4.9e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAX28996.1 - 1.5e-10 41.4 0.0 5.4e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAX28996.1 - 4.2e-09 36.6 0.0 9.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 GAX28998.1 - 1.3e-07 31.9 9.1 2.8e-06 27.7 9.1 2.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX28998.1 - 0.0043 17.6 6.8 0.039 14.6 6.8 2.6 1 1 0 1 1 1 1 HMG-box domain tRNA-synt_1c PF00749.21 GAX28998.1 - 0.25 10.2 3.6 0.38 9.6 3.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain F_bP_aldolase PF01116.20 GAX29000.1 - 2.6e-86 289.6 0.0 3.1e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Enolase_C PF00113.22 GAX29001.1 - 9.1e-132 438.8 0.0 1.2e-131 438.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAX29001.1 - 9e-55 184.4 0.3 1.6e-54 183.6 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAX29001.1 - 1.2e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAX29001.1 - 1.8e-06 27.3 0.3 3.8e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Dpy-30 PF05186.13 GAX29004.1 - 3.9e-18 64.9 0.5 5.2e-18 64.5 0.5 1.2 1 0 0 1 1 1 1 Dpy-30 motif RdDM_RDM1 PF09187.10 GAX29004.1 - 0.033 14.3 0.7 0.053 13.6 0.1 1.6 1 1 1 2 2 2 0 RNA-directed DNA methylation 1 IreB PF06135.12 GAX29004.1 - 0.033 14.4 0.7 0.052 13.8 0.0 1.7 2 0 0 2 2 2 0 IreB regulatory phosphoprotein Spt20 PF12090.8 GAX29004.1 - 0.29 10.7 11.5 0.23 11.0 11.5 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 GAX29004.1 - 1 9.3 14.1 1 9.3 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 GAX29004.1 - 2.1 7.2 29.8 2.6 6.9 29.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Toxin_35 PF10530.9 GAX29005.1 - 4.1e-05 23.5 6.7 4.1e-05 23.5 6.7 14.2 4 3 10 14 14 14 2 Toxin with inhibitor cystine knot ICK or Knottin scaffold CRAL_TRIO PF00650.20 GAX29006.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO domain EamA PF00892.20 GAX29007.1 - 4.9e-09 36.5 21.3 3.4e-08 33.7 7.5 2.7 2 1 0 2 2 2 2 EamA-like transporter family CBM_6 PF03422.15 GAX29009.1 - 3.4e-23 82.3 0.1 2.9e-14 53.4 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX29009.1 - 2.1e-09 37.5 0.1 0.0016 18.6 0.0 2.5 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX29009.1 - 3.9e-07 30.3 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) TRAM_LAG1_CLN8 PF03798.16 GAX29014.1 - 1.6e-06 28.0 9.4 3.7e-06 26.8 9.4 1.7 1 1 0 1 1 1 1 TLC domain PIRT PF15099.6 GAX29014.1 - 0.022 14.3 0.3 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family FPN1 PF06963.12 GAX29014.1 - 0.05 12.2 0.1 0.076 11.6 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4234 PF14018.6 GAX29014.1 - 3.9 7.7 8.4 1.8 8.8 3.5 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4234) PGK PF00162.19 GAX29015.1 - 3.4e-133 444.2 0.0 4.3e-133 443.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase MTS PF05175.14 GAX29015.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Nitro_FeMo-Co PF02579.17 GAX29015.1 - 0.067 13.5 0.2 0.76 10.1 0.0 2.7 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor Aa_trans PF01490.18 GAX29017.1 - 4.2e-26 91.6 17.6 1.7e-20 73.1 13.6 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Fasciclin PF02469.22 GAX29018.1 - 5.8e-21 75.0 0.0 1.6e-07 31.6 0.1 4.5 4 0 0 4 4 4 4 Fasciclin domain DUF525 PF04379.14 GAX29019.1 - 3.2e-20 72.2 0.0 6.7e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 ApaG domain Complex1_LYR PF05347.15 GAX29019.1 - 0.0038 17.2 0.2 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) INCENP_ARK-bind PF03941.15 GAX29019.1 - 0.02 14.8 1.3 0.02 14.8 1.3 2.2 3 0 0 3 3 3 0 Inner centromere protein, ARK binding region SDH_alpha PF03313.15 GAX29019.1 - 0.23 11.1 0.0 0.32 10.6 0.0 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain Fasciclin PF02469.22 GAX29021.1 - 3.3e-63 211.6 0.0 1.6e-20 73.6 0.1 3.1 3 0 0 3 3 3 3 Fasciclin domain DUF4993 PF16384.5 GAX29021.1 - 0.0094 15.0 0.0 3.5 6.5 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function Dynamin_N PF00350.23 GAX29022.1 - 5.6e-11 42.8 0.0 1.5e-07 31.6 0.0 2.4 1 1 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 GAX29022.1 - 2.4e-06 27.6 0.0 1.1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX29022.1 - 8.9e-05 22.5 0.0 0.41 10.5 0.0 3.5 4 0 0 4 4 4 2 RsgA GTPase AAA_16 PF13191.6 GAX29022.1 - 0.0028 18.1 1.0 0.16 12.3 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AIG1 PF04548.16 GAX29022.1 - 0.0084 15.5 0.0 0.2 11.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 GAX29022.1 - 0.014 14.9 0.1 0.83 9.2 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 GAX29022.1 - 0.12 12.6 0.3 0.71 10.1 0.0 2.4 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ubiquitin PF00240.23 GAX29023.1 - 3.8e-24 84.2 0.4 4.2e-24 84.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAX29023.1 - 4.8e-13 48.7 0.3 5.3e-13 48.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAX29023.1 - 1.7e-06 28.3 0.1 2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 GAX29023.1 - 7.3e-05 23.2 0.2 0.00027 21.4 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAX29023.1 - 0.00099 19.2 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAX29023.1 - 0.026 15.1 0.0 0.031 14.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Innexin PF00876.18 GAX29024.1 - 0.082 12.2 0.4 0.11 11.8 0.4 1.2 1 0 0 1 1 1 0 Innexin FTCD_C PF04961.12 GAX29024.1 - 0.11 12.2 4.2 0.23 11.2 0.6 2.1 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase TFIIA PF03153.13 GAX29024.1 - 0.21 11.5 9.5 0.26 11.2 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1700 PF08006.11 GAX29024.1 - 0.28 10.7 0.2 0.39 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Allexi_40kDa PF05549.11 GAX29024.1 - 1.3 8.4 7.5 0.73 9.3 3.2 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein Lge1 PF11488.8 GAX29024.1 - 1.6 9.0 8.6 3.4 7.9 7.8 2.1 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Csm1_N PF18504.1 GAX29024.1 - 3.1 8.2 11.8 0.51 10.7 4.7 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF4407 PF14362.6 GAX29024.1 - 9.1 5.5 10.0 11 5.2 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.32 GAX29028.1 - 4.2e-12 46.4 11.7 0.073 14.0 0.0 7.3 7 0 0 7 7 6 3 WD domain, G-beta repeat GIY-YIG PF01541.24 GAX29028.1 - 6e-07 29.6 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-CCHC_5 PF14787.6 GAX29028.1 - 7.3e-07 28.8 7.9 0.0041 16.8 2.1 2.9 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCCH PF00642.24 GAX29028.1 - 4.2e-06 26.5 0.3 4.2e-06 26.5 0.3 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAX29028.1 - 5.5e-06 26.3 1.0 5.5e-06 26.3 1.0 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 GAX29028.1 - 7e-05 22.5 0.8 0.00021 21.0 0.8 1.9 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCHC_3 PF13917.6 GAX29028.1 - 0.00012 22.0 9.1 0.00031 20.6 1.5 3.0 3 0 0 3 3 3 1 Zinc knuckle Nucleoporin_N PF08801.11 GAX29028.1 - 0.00038 19.3 0.0 3.9 6.1 0.0 3.8 1 1 3 4 4 4 2 Nup133 N terminal like zf-CCCH_2 PF14608.6 GAX29028.1 - 0.0012 19.2 1.4 0.0012 19.2 1.4 2.3 2 0 0 2 2 1 1 RNA-binding, Nab2-type zinc finger ANAPC4_WD40 PF12894.7 GAX29028.1 - 0.0016 18.7 0.4 0.1 12.9 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAX29028.1 - 0.0083 16.2 0.0 1.3 9.1 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 GAX29028.1 - 0.049 12.3 0.0 7 5.2 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 eIF3g PF12353.8 GAX29028.1 - 0.068 13.6 0.6 4.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Lustrin_cystein PF14625.6 GAX29028.1 - 0.09 13.2 3.5 0.24 11.8 0.5 3.0 3 0 0 3 3 2 0 Lustrin, cysteine-rich repeated domain Torus PF16131.5 GAX29028.1 - 0.31 11.8 4.3 2.1 9.1 0.0 2.9 2 1 1 3 3 3 0 Torus domain zf-CCHC PF00098.23 GAX29028.1 - 2 8.7 19.0 0.087 12.9 4.2 3.7 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.6 GAX29029.1 - 1e-27 95.5 19.9 4.2e-07 29.5 0.3 5.4 5 0 0 5 5 5 5 GAG-polyprotein viral zinc-finger GIY-YIG PF01541.24 GAX29029.1 - 4.7e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GAX29029.1 - 0.00011 22.1 1.5 0.00011 22.1 1.5 5.6 5 0 0 5 5 5 2 Zinc knuckle zf-CCHC_4 PF14392.6 GAX29029.1 - 0.0007 19.3 33.0 0.63 9.8 0.3 5.3 5 0 0 5 5 5 5 Zinc knuckle T5orf172 PF10544.9 GAX29029.1 - 0.016 15.8 0.2 0.048 14.2 0.0 2.0 2 0 0 2 2 2 0 T5orf172 domain zf-CCHC_3 PF13917.6 GAX29029.1 - 0.048 13.6 17.4 2.2 8.3 1.0 5.3 5 0 0 5 5 5 0 Zinc knuckle Sec23_BS PF08033.12 GAX29030.1 - 3e-13 50.3 0.0 5.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 GAX29030.1 - 4.9e-11 42.7 0.0 1.1e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAX29030.1 - 5e-08 32.7 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 GAX29030.1 - 3.7e-06 26.7 0.0 9e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 GAX29030.1 - 0.016 15.2 2.1 0.041 13.9 2.1 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Sulfotransfer_4 PF17784.1 GAX29031.1 - 7.5e-08 32.5 0.5 1.3e-07 31.7 0.5 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX29031.1 - 0.00081 19.8 2.1 0.0082 16.6 2.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family DUF4070 PF13282.6 GAX29031.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) Peptidase_S8 PF00082.22 GAX29032.1 - 2.3e-40 138.8 2.4 4.1e-40 137.9 2.4 1.4 1 0 0 1 1 1 1 Subtilase family SOUL PF04832.12 GAX29034.1 - 0.016 15.4 0.4 0.044 13.9 0.3 1.8 1 1 0 1 1 1 0 SOUL heme-binding protein Phospholamban PF04272.14 GAX29035.1 - 0.0054 16.2 1.1 0.034 13.6 0.1 2.6 2 0 0 2 2 2 1 Phospholamban TPR_2 PF07719.17 GAX29036.1 - 0.019 15.0 0.0 3.8 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DEC1 PF15859.5 GAX29036.1 - 0.04 13.9 0.2 0.096 12.7 0.2 1.5 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family AP3D1 PF06375.11 GAX29036.1 - 0.47 10.7 3.7 1 9.6 2.9 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Flagellin_N PF00669.20 GAX29036.1 - 3.9 7.6 6.2 1 9.5 0.5 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region SpoU_methylase PF00588.19 GAX29037.1 - 1.2e-22 80.6 0.0 2.4e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family PPS_PS PF02006.16 GAX29037.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase ABC1 PF03109.16 GAX29038.1 - 1.5e-22 80.0 0.0 3.2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX29038.1 - 1.1e-05 25.5 1.5 7e-05 22.9 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAX29038.1 - 0.013 14.9 0.0 0.23 10.8 0.0 2.5 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.20 GAX29038.1 - 0.16 11.5 0.1 0.44 10.1 0.1 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase CMAS PF02353.20 GAX29039.1 - 7.8e-83 277.9 0.0 1e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 GAX29039.1 - 1.5e-14 54.4 0.0 4.4e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX29039.1 - 2.7e-13 50.4 0.0 5.8e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX29039.1 - 4.9e-13 49.3 0.0 7.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX29039.1 - 1e-08 35.8 0.0 4.7e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX29039.1 - 3e-08 33.6 0.0 5.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 GAX29039.1 - 0.00014 21.6 0.0 0.0057 16.3 0.0 2.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 GAX29039.1 - 0.0018 17.9 0.0 0.0052 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 GAX29039.1 - 0.0028 17.4 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 GAX29039.1 - 0.014 15.0 0.0 0.064 12.8 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 GAX29039.1 - 0.044 13.9 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.20 GAX29039.1 - 0.085 11.9 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 GAX29039.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CENP-T_C PF15511.6 GAX29040.1 - 7.7e-07 29.2 0.1 9.5e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 GAX29040.1 - 0.0048 17.3 0.3 0.0058 17.0 0.3 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAX29040.1 - 0.0048 17.2 0.3 0.0064 16.9 0.3 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 GAX29040.1 - 0.0063 16.7 0.2 0.0091 16.1 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 GAX29040.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 GAX29040.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Metal_resist PF13801.6 GAX29041.1 - 0.033 14.4 1.1 0.033 14.4 1.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance SF1-HH PF16275.5 GAX29041.1 - 0.039 14.3 0.2 9.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain FRB_dom PF08771.11 GAX29041.1 - 0.066 13.6 0.2 2.8 8.4 0.0 2.1 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain DUF4122 PF13498.6 GAX29041.1 - 0.15 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) DUF4407 PF14362.6 GAX29041.1 - 0.18 11.1 0.1 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DFRP_C PF16543.5 GAX29042.1 - 6.4e-14 52.2 7.1 6.4e-14 52.2 7.1 3.4 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 DUF4207 PF13904.6 GAX29042.1 - 0.011 15.5 7.9 0.011 15.5 7.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF4718 PF15842.5 GAX29042.1 - 0.32 10.8 5.9 0.69 9.7 5.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) ATP-grasp_5 PF13549.6 GAX29044.1 - 2.5e-76 256.0 0.0 3.8e-76 255.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 GAX29044.1 - 8.2e-50 168.2 0.1 2.5e-49 166.6 0.1 1.9 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAX29044.1 - 1.2e-24 87.0 0.7 1.2e-23 83.8 0.2 2.9 3 1 1 4 4 4 1 CoA binding domain CoA_binding PF02629.19 GAX29044.1 - 8.7e-12 45.6 0.2 2.8e-11 43.9 0.2 2.0 1 0 0 1 1 1 1 CoA binding domain zf-C2H2 PF00096.26 GAX29045.1 - 0.026 15.0 6.4 7.1 7.3 4.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAX29045.1 - 0.052 14.4 8.3 1.2 10.2 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 GAX29045.1 - 0.1 13.1 4.5 0.19 12.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAX29045.1 - 0.49 10.8 3.7 6.3 7.2 0.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 GAX29045.1 - 2.1 8.5 7.8 4.3 7.6 0.1 2.4 1 1 1 2 2 2 0 FYVE zinc finger peroxidase PF00141.23 GAX29047.1 - 1.3e-17 64.3 0.0 2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase 2OG-FeII_Oxy_3 PF13640.6 GAX29048.1 - 2.5e-13 50.7 0.0 4.4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAX29048.1 - 4.7e-05 23.8 0.0 9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_16 PF13191.6 GAX29049.1 - 0.00042 20.8 0.1 0.0045 17.4 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 GAX29049.1 - 0.00078 18.7 0.0 0.0037 16.5 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain PRK PF00485.18 GAX29049.1 - 0.0024 17.7 0.0 0.0048 16.7 0.0 1.8 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 GAX29049.1 - 0.0069 16.1 0.3 0.14 11.8 0.0 2.4 3 0 0 3 3 3 1 Dephospho-CoA kinase AAA_33 PF13671.6 GAX29049.1 - 0.016 15.3 0.4 0.098 12.8 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX29049.1 - 0.021 15.4 0.1 0.045 14.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAX29049.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 GAX29049.1 - 0.038 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 GAX29049.1 - 0.043 13.1 0.0 0.093 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 GAX29049.1 - 0.049 13.1 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 GAX29049.1 - 0.085 12.8 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 GAX29049.1 - 0.1 12.9 0.0 0.26 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAX29049.1 - 0.12 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 GAX29049.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_30 PF13604.6 GAX29049.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAX29049.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 GAX29049.1 - 0.22 11.9 0.4 0.73 10.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 GAX29050.1 - 8.6e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAX29050.1 - 0.0012 19.4 0.0 0.0024 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAX29050.1 - 0.0026 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 GAX29050.1 - 0.0027 16.9 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAX29050.1 - 0.0048 17.3 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 GAX29050.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAX29050.1 - 0.013 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 GAX29050.1 - 0.016 15.4 0.3 0.042 14.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 GAX29050.1 - 0.026 14.2 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 GAX29050.1 - 0.037 13.3 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 GAX29050.1 - 0.055 12.7 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 GAX29050.1 - 0.075 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 GAX29050.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAX29050.1 - 0.09 13.1 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAX29050.1 - 0.095 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAX29050.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAX29050.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TrwB_AAD_bind PF10412.9 GAX29050.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KAP_NTPase PF07693.14 GAX29050.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.29 GAX29050.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Gp_dh_C PF02800.20 GAX29054.1 - 1e-65 220.1 0.0 1.5e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAX29054.1 - 4.9e-35 119.9 0.0 9.5e-35 119.0 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAX29054.1 - 0.014 15.5 0.0 0.063 13.4 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 GAX29054.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4451 PF14616.6 GAX29054.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) PHD PF00628.29 GAX29055.1 - 6.3e-08 32.4 14.9 1.4e-07 31.3 14.9 1.6 1 0 0 1 1 1 1 PHD-finger ELM2 PF01448.24 GAX29055.1 - 1.4e-05 25.8 0.2 6.8e-05 23.5 0.2 2.3 1 0 0 1 1 1 1 ELM2 domain PDZ_6 PF17820.1 GAX29055.1 - 0.0006 19.6 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 GAX29055.1 - 0.00087 19.6 0.0 0.29 11.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PHD_2 PF13831.6 GAX29055.1 - 0.0054 16.3 5.3 0.013 15.0 5.3 1.7 1 0 0 1 1 1 1 PHD-finger PDZ_2 PF13180.6 GAX29055.1 - 0.13 12.6 0.0 15 6.0 0.0 3.1 3 0 0 3 3 3 0 PDZ domain Astro_capsid_p PF12226.8 GAX29055.1 - 0.38 9.8 6.2 0.67 9.1 6.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Kinesin PF00225.23 GAX29056.1 - 3.6e-15 55.7 0.0 3.5e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GAX29056.1 - 4e-05 23.6 0.0 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 Microtubule binding NRBF2 PF08961.10 GAX29056.1 - 0.0029 17.2 1.2 0.0067 16.0 0.3 2.0 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 GAX29056.1 - 0.012 15.7 2.4 0.012 15.7 2.4 2.7 3 0 0 3 3 3 0 bZIP transcription factor CCDC106 PF15794.5 GAX29056.1 - 0.014 15.1 1.3 0.014 15.1 1.3 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 bZIP_2 PF07716.15 GAX29056.1 - 0.03 14.4 0.4 0.12 12.4 0.4 2.1 1 0 0 1 1 1 0 Basic region leucine zipper YabA PF06156.13 GAX29056.1 - 0.053 14.2 7.2 2.4 8.9 0.5 3.1 3 0 0 3 3 3 0 Initiation control protein YabA Gln-synt_C-ter PF18318.1 GAX29059.1 - 0.063 13.1 1.5 0.092 12.6 1.5 1.3 1 0 0 1 1 1 0 Glutamine synthetase C-terminal domain GpcrRhopsn4 PF10192.9 GAX29060.1 - 1.1e-27 97.1 6.2 1.9e-27 96.3 6.2 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain TFIIS_M PF07500.14 GAX29062.1 - 5.1e-17 62.4 1.9 7.3e-17 61.9 0.1 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain DUF745 PF05335.13 GAX29062.1 - 0.001 18.8 0.1 0.0029 17.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF745) CarboxypepD_reg PF13620.6 GAX29062.1 - 0.062 13.6 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF1758 PF05585.12 GAX29062.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF1758) PhzC-PhzF PF02567.16 GAX29064.1 - 9.5e-54 182.8 0.1 1.4e-53 182.2 0.1 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 GAX29064.1 - 6.2e-08 32.9 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAX29064.1 - 3.4e-07 30.6 0.0 7.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAX29064.1 - 2.1e-06 27.7 0.0 4.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX29064.1 - 0.00066 19.8 0.0 0.0059 16.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pro_racemase PF05544.11 GAX29064.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Proline racemase Acetyltransf_CG PF14542.6 GAX29064.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 GAX29064.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase AAA_33 PF13671.6 GAX29065.1 - 0.044 13.9 0.6 0.15 12.2 0.5 1.8 2 0 0 2 2 2 0 AAA domain EMP24_GP25L PF01105.24 GAX29066.1 - 8.4e-18 65.0 0.0 1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HK_sensor PF16750.5 GAX29066.1 - 0.12 12.6 0.0 0.66 10.3 0.0 2.2 1 1 1 2 2 2 0 Sensor domain of 2-component histidine kinase Peptidase_S24 PF00717.23 GAX29067.1 - 8.4e-11 41.7 0.3 1.4e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase S24-like Bud13 PF09736.9 GAX29068.1 - 2.9e-34 118.5 6.5 2.9e-34 118.5 6.5 4.2 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex SR-25 PF10500.9 GAX29068.1 - 0.01 15.5 5.1 0.01 15.5 5.1 3.4 1 1 3 4 4 4 0 Nuclear RNA-splicing-associated protein DUF4994 PF16385.5 GAX29068.1 - 0.015 15.2 0.2 0.089 12.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function OAD_gamma PF04277.13 GAX29068.1 - 1.6 9.4 3.6 1.7 9.3 1.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Aldose_epim PF01263.20 GAX29070.1 - 2e-34 119.3 0.0 2.5e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase TMEM189_B_dmain PF10520.9 GAX29072.1 - 1.2e-54 185.1 0.2 1.8e-54 184.5 0.2 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 GAX29072.1 - 8e-05 23.0 0.4 8e-05 23.0 0.4 1.8 1 1 0 2 2 2 1 Fatty acid hydroxylase superfamily bMG1 PF17970.1 GAX29072.1 - 0.062 13.4 0.2 12 6.0 0.0 2.6 2 1 1 3 3 3 0 Bacterial Alpha-2-macroglobulin MG1 domain DUF962 PF06127.11 GAX29075.1 - 1.2e-07 31.7 6.7 7.2e-07 29.2 6.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3021 PF11457.8 GAX29075.1 - 0.099 13.0 8.1 0.44 10.9 8.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Glycos_transf_1 PF00534.20 GAX29076.1 - 4.7e-32 110.9 0.0 7.7e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAX29076.1 - 1.7e-26 93.2 0.0 2.9e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAX29076.1 - 1e-21 77.7 0.2 4.5e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAX29076.1 - 2.9e-14 53.8 0.0 2.1e-13 51.0 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAX29076.1 - 3.5e-11 43.4 0.0 4.1e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 GAX29076.1 - 0.027 14.5 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF2968 PF11180.8 GAX29077.1 - 0.015 15.0 12.4 0.11 12.1 7.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) G-alpha PF00503.20 GAX29077.1 - 0.052 12.7 0.5 0.073 12.2 0.5 1.3 1 0 0 1 1 1 0 G-protein alpha subunit bZIP_1 PF00170.21 GAX29077.1 - 0.11 12.6 9.5 0.035 14.2 5.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor Nucleolin_bd PF16725.5 GAX29077.1 - 0.11 12.1 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 Nucleolin binding domain YabA PF06156.13 GAX29077.1 - 0.13 12.9 8.0 0.061 14.0 3.0 2.6 2 0 0 2 2 2 0 Initiation control protein YabA WHEP-TRS PF00458.20 GAX29077.1 - 0.4 10.9 0.1 0.4 10.9 0.1 2.1 3 0 0 3 3 3 0 WHEP-TRS domain KIAA1430 PF13879.6 GAX29077.1 - 0.83 10.4 9.5 0.08 13.7 3.8 2.2 2 0 0 2 2 2 0 KIAA1430 homologue DUF16 PF01519.16 GAX29077.1 - 0.84 10.2 4.9 1.1 9.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 GAX29077.1 - 1.6 9.0 10.4 1.2 9.3 3.2 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Rootletin PF15035.6 GAX29077.1 - 3.2 7.7 13.1 0.87 9.6 9.0 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Beta_helix PF13229.6 GAX29078.1 - 2.3e-06 27.5 0.1 0.00032 20.6 0.1 2.7 1 1 2 3 3 3 3 Right handed beta helix region Syntaxin-6_N PF09177.11 GAX29082.1 - 0.089 13.4 1.1 0.67 10.5 0.1 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4477 PF14780.6 GAX29082.1 - 0.11 12.2 0.7 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) UPRTase PF14681.6 GAX29083.1 - 1.2e-63 214.3 0.0 1.4e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAX29083.1 - 0.0099 15.4 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Baculo_PEP_C PF04513.12 GAX29084.1 - 0.00035 20.6 1.0 0.00035 20.6 1.0 4.5 4 1 1 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 GAX29084.1 - 0.0028 18.2 12.7 0.0028 18.2 12.7 5.9 2 1 5 7 7 7 2 Apg6 coiled-coil region Pox_A_type_inc PF04508.12 GAX29084.1 - 0.98 9.4 11.8 1.3 9.0 0.6 5.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat PNTB PF02233.16 GAX29085.1 - 1.1e-173 578.4 16.4 1.1e-173 578.4 16.4 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAX29085.1 - 3.1e-71 239.1 1.5 3.1e-71 239.1 1.5 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAX29085.1 - 2.1e-42 144.6 0.0 4.8e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAX29085.1 - 8.7e-27 93.4 9.5 8.7e-27 93.4 9.5 3.0 3 2 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 GAX29085.1 - 0.00021 20.7 0.2 0.03 13.7 0.1 3.4 4 0 0 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAX29085.1 - 0.0024 17.8 2.5 0.0078 16.2 0.1 3.1 4 0 0 4 4 4 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 GAX29085.1 - 0.0097 15.2 0.1 0.022 14.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX29085.1 - 0.16 12.2 4.1 1.1 9.6 0.2 3.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain CcmH PF03918.14 GAX29086.1 - 0.75 9.1 5.6 0.65 9.3 0.4 3.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein CDP-OH_P_transf PF01066.21 GAX29087.1 - 3.1e-11 43.9 0.0 8.6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Methyltransf_21 PF05050.12 GAX29088.1 - 7.6e-13 48.8 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Acetyltransf_7 PF13508.7 GAX29089.1 - 4.2e-08 33.5 0.1 1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAX29089.1 - 4.6e-06 26.9 0.1 2.3e-05 24.6 0.1 2.1 2 1 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX29089.1 - 6.7e-06 26.1 0.4 4.5e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX29089.1 - 0.0013 18.9 0.0 0.0028 17.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX29089.1 - 0.0025 17.7 0.0 0.031 14.2 0.0 2.4 2 1 1 3 3 3 1 FR47-like protein RibD_C PF01872.17 GAX29089.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Amino_oxidase PF01593.24 GAX29090.1 - 4.9e-52 177.7 0.0 5.7e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX29090.1 - 6.6e-07 29.5 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX29090.1 - 0.0018 17.9 0.0 0.0078 15.8 0.0 2.0 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAX29090.1 - 0.052 12.9 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAX29090.1 - 0.061 12.4 0.0 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 GAX29090.1 - 0.089 12.0 0.0 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CooC_C PF15976.5 GAX29090.1 - 0.095 12.8 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 CS1-pili formation C-terminal Peptidase_M3 PF01432.20 GAX29092.1 - 3.8e-102 342.9 2.2 3.8e-102 342.9 2.2 1.7 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 GAX29092.1 - 2.5 7.7 5.7 0.25 10.9 0.7 1.8 2 0 0 2 2 2 0 Peptidase M50B-like PGI PF00342.19 GAX29093.1 - 5.7e-190 632.1 0.0 6.9e-190 631.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF3992 PF13157.6 GAX29093.1 - 0.0072 17.0 0.1 0.017 15.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3992) Phage_int_SAM_4 PF13495.6 GAX29094.1 - 0.011 16.2 0.0 0.037 14.5 0.0 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PDE8 PF08629.10 GAX29094.1 - 0.1 12.6 0.5 0.56 10.2 1.1 1.9 2 0 0 2 2 2 0 PDE8 phosphodiesterase Folate_rec PF03024.14 GAX29095.1 - 0.025 14.5 0.4 0.037 13.9 0.4 1.3 1 0 0 1 1 1 0 Folate receptor family CrtC PF07143.11 GAX29095.1 - 0.03 15.0 0.2 0.044 14.5 0.2 1.3 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain Lipase_3 PF01764.25 GAX29096.1 - 2e-24 86.1 0.0 4e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) Ras PF00071.22 GAX29097.1 - 4.1e-61 205.3 0.1 4.9e-61 205.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX29097.1 - 3.9e-36 123.9 0.1 6.7e-36 123.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX29097.1 - 1.4e-15 57.2 0.0 1.8e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX29097.1 - 2.8e-07 30.6 0.0 4.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAX29097.1 - 1.2e-05 25.3 0.1 0.018 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAX29097.1 - 1.3e-05 24.8 0.1 5.4e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAX29097.1 - 0.0011 18.5 0.1 0.19 11.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAX29097.1 - 0.0012 19.3 0.1 0.0022 18.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 GAX29097.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 GAX29097.1 - 0.0016 18.7 0.0 0.014 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAX29097.1 - 0.0033 18.0 0.4 0.024 15.2 0.4 2.1 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 GAX29097.1 - 0.0077 16.0 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 GAX29097.1 - 0.016 14.4 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 GAX29097.1 - 0.02 14.6 0.1 0.046 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 GAX29097.1 - 0.022 14.2 0.0 0.044 13.2 0.0 1.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 GAX29097.1 - 0.026 14.5 0.0 0.066 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 GAX29097.1 - 0.036 13.5 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein DUF2868 PF11067.8 GAX29097.1 - 0.064 12.8 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Ploopntkinase3 PF18751.1 GAX29097.1 - 0.091 12.7 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MCM PF00493.23 GAX29097.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 GAX29097.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.6 1 1 0 1 1 1 0 NTPase Ion_trans_2 PF07885.16 GAX29098.1 - 1.5e-50 169.0 53.3 5e-14 52.0 6.3 4.2 4 0 0 4 4 4 4 Ion channel Ion_trans PF00520.31 GAX29098.1 - 5.6e-05 22.5 26.4 0.096 11.9 0.7 4.2 3 1 1 4 4 4 4 Ion transport protein Lig_chan PF00060.26 GAX29098.1 - 0.00074 19.4 23.2 0.0017 18.2 0.2 3.9 2 1 2 4 4 4 2 Ligand-gated ion channel IRK PF01007.20 GAX29098.1 - 0.0017 18.2 12.8 1 9.1 0.1 4.7 4 1 0 4 4 4 3 Inward rectifier potassium channel transmembrane domain H_PPase PF03030.16 GAX29098.1 - 1.9 7.0 5.7 0.49 9.0 1.2 2.0 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase AAA_6 PF12774.7 GAX29100.1 - 4.5e-127 423.6 0.0 1.3e-125 418.7 0.0 2.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GAX29100.1 - 2.6e-107 359.4 7.1 8.9e-107 357.6 0.1 4.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 GAX29100.1 - 1.4e-76 258.3 8.7 1.4e-76 258.3 8.7 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 GAX29100.1 - 1.6e-68 230.2 0.0 1.6e-68 230.2 0.0 2.9 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 GAX29100.1 - 1.7e-62 211.1 0.0 6.1e-62 209.3 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 GAX29100.1 - 3.7e-36 124.8 8.4 1.1e-35 123.3 8.4 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 GAX29100.1 - 5.8e-36 123.7 0.0 5e-32 110.9 0.0 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 GAX29100.1 - 5.6e-28 97.8 0.0 1.3e-27 96.6 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GAX29100.1 - 2.2e-24 85.8 0.0 3.8e-23 81.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 GAX29100.1 - 5e-22 78.4 0.2 3.5e-08 33.5 0.0 7.0 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 GAX29100.1 - 5.4e-18 65.3 3.6 7.6e-18 64.8 0.1 3.1 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 GAX29100.1 - 8e-14 52.2 0.0 0.0026 18.2 0.0 4.5 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX29100.1 - 2.6e-08 34.4 2.3 1.5 9.2 0.0 7.3 6 1 0 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 GAX29100.1 - 1.2e-06 28.8 15.8 0.018 15.3 0.1 8.2 10 1 1 11 11 6 2 AAA domain T2SSE PF00437.20 GAX29100.1 - 3.4e-06 26.3 0.0 0.017 14.2 0.0 4.9 5 0 0 5 5 5 1 Type II/IV secretion system protein AAA_33 PF13671.6 GAX29100.1 - 1.2e-05 25.5 1.8 0.019 15.2 0.0 5.2 6 0 0 6 6 4 1 AAA domain AAA_18 PF13238.6 GAX29100.1 - 1.8e-05 25.3 0.1 2.1 8.9 0.0 5.1 4 0 0 4 4 3 1 AAA domain AAA_lid_1 PF17857.1 GAX29100.1 - 5.5e-05 23.3 0.0 0.00024 21.2 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_25 PF13481.6 GAX29100.1 - 0.00077 19.1 0.1 0.16 11.5 0.0 4.1 3 0 0 3 3 3 1 AAA domain BRE1 PF08647.11 GAX29100.1 - 0.0027 17.7 4.3 0.0027 17.7 4.3 4.6 3 1 0 3 3 2 1 BRE1 E3 ubiquitin ligase AAA_30 PF13604.6 GAX29100.1 - 0.0059 16.3 1.8 4.4 7.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 GAX29100.1 - 0.0081 16.5 0.9 0.56 10.5 0.0 3.9 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 GAX29100.1 - 0.048 13.7 1.0 5.2 7.1 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 GAX29100.1 - 0.052 13.5 0.0 11 5.9 0.0 3.3 3 0 0 3 3 2 0 RsgA GTPase RuvB_N PF05496.12 GAX29100.1 - 0.054 13.2 0.0 2.5 7.8 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 GAX29100.1 - 0.086 12.8 0.1 5.2 7.0 0.0 3.3 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 GAX29100.1 - 0.096 12.4 0.2 4.3 7.0 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 GAX29100.1 - 0.14 11.9 0.4 46 3.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 GAX29100.1 - 0.17 12.3 0.1 35 4.9 0.0 3.6 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 GAX29100.1 - 0.18 12.3 0.9 20 5.7 0.0 4.3 4 0 0 4 4 2 0 ABC transporter Drf_GBD PF06371.13 GAX29100.1 - 0.19 11.3 3.2 0.98 9.0 2.1 2.6 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Mg_chelatase PF01078.21 GAX29100.1 - 0.66 9.3 5.4 2.7 7.3 0.1 3.2 3 1 0 3 3 2 0 Magnesium chelatase, subunit ChlI zf-C4H2 PF10146.9 GAX29100.1 - 1.6 9.0 14.1 0.34 11.2 0.2 3.2 2 0 0 2 2 2 0 Zinc finger-containing protein Aldolase_II PF00596.21 GAX29101.1 - 2.3e-42 145.0 0.0 3.6e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 GAX29101.1 - 5e-06 27.0 0.0 2.6e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAX29101.1 - 8.8e-05 22.7 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAX29101.1 - 0.0043 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Spt20 PF12090.8 GAX29101.1 - 0.046 13.3 0.1 0.25 10.9 0.0 2.0 1 1 1 2 2 2 0 Spt20 family PseudoU_synth_1 PF01416.20 GAX29102.1 - 5.9e-20 71.8 0.2 2e-13 50.7 0.1 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase HCV_NS5a_1a PF08300.13 GAX29102.1 - 0.055 13.6 0.2 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain Peptidase_S26 PF10502.9 GAX29103.1 - 0.0016 18.2 0.0 0.24 11.2 0.0 2.8 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 GAX29103.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase S24-like Transketolase_N PF00456.21 GAX29104.1 - 5.7e-109 364.1 2.3 8.1e-109 363.6 2.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAX29104.1 - 8.2e-35 120.1 0.0 1.6e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAX29104.1 - 3.2e-09 36.7 0.0 8.6e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAX29104.1 - 9.2e-07 28.3 0.0 4.2e-05 22.9 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GAX29104.1 - 0.00035 20.4 1.6 0.0028 17.5 0.4 3.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 GAX29104.1 - 0.006 15.6 0.2 0.012 14.6 0.2 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF3986 PF13143.6 GAX29104.1 - 0.13 13.3 1.3 2.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) DUF4275 PF14101.6 GAX29104.1 - 0.19 11.9 0.7 0.41 10.8 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) VPS9 PF02204.18 GAX29105.1 - 4.1e-11 43.0 0.2 9.5e-11 41.8 0.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Prok-RING_1 PF14446.6 GAX29105.1 - 0.011 15.6 7.1 0.011 15.6 7.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Phage_holin_5_2 PF16079.5 GAX29105.1 - 8.3 6.8 6.2 19 5.6 6.2 1.6 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V PPR_2 PF13041.6 GAX29107.1 - 2.6e-60 200.4 13.9 1.1e-11 44.8 0.0 9.6 2 1 8 10 10 10 9 PPR repeat family PPR PF01535.20 GAX29107.1 - 1.9e-48 159.4 22.2 8.8e-06 25.6 0.1 11.1 11 0 0 11 11 11 8 PPR repeat PPR_3 PF13812.6 GAX29107.1 - 3.1e-45 152.1 0.0 1.3e-11 44.4 0.0 6.5 1 1 0 6 6 6 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAX29107.1 - 1.4e-30 104.6 0.0 5.9e-05 22.7 0.0 9.4 8 1 0 8 8 8 7 PPR repeat PPR_long PF17177.4 GAX29107.1 - 4.9e-25 88.1 4.6 1.2e-09 37.9 0.1 3.4 1 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 GAX29107.1 - 0.055 12.6 0.1 0.2 10.7 0.0 1.9 2 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF2594 PF10769.9 GAX29107.1 - 0.11 12.5 0.1 15 5.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2594) ANAPC3 PF12895.7 GAX29107.1 - 0.19 12.0 1.3 36 4.7 0.0 3.2 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF982 PF06169.12 GAX29107.1 - 4 7.5 5.0 2.7 8.1 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF982) FKBP_C PF00254.28 GAX29109.1 - 3.6e-18 65.7 0.0 7.1e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ABC1 PF03109.16 GAX29110.1 - 1.2e-28 99.7 0.0 3.2e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAX29110.1 - 0.00062 19.8 0.6 0.14 12.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Phe_tRNA-synt_N PF02912.18 GAX29110.1 - 0.055 13.4 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Pkinase_fungal PF17667.1 GAX29110.1 - 0.2 10.4 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 GAX29112.1 - 4.4e-05 24.0 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Syntaxin_2 PF14523.6 GAX29112.1 - 0.00066 20.0 4.5 0.0027 18.0 4.5 2.1 1 0 0 1 1 1 1 Syntaxin-like protein Ank_5 PF13857.6 GAX29112.1 - 0.00086 19.6 0.1 0.018 15.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX29112.1 - 0.00096 19.7 0.1 0.0024 18.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Flu_M1_C PF08289.11 GAX29112.1 - 0.1 12.8 0.8 0.42 10.8 0.3 2.3 1 1 1 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain TetR_C_24 PF17932.1 GAX29112.1 - 0.32 11.3 4.0 59 4.0 0.0 3.9 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain LMBR1 PF04791.16 GAX29112.1 - 0.79 8.6 6.0 1.1 8.1 6.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Tup_N PF08581.10 GAX29112.1 - 2.6 8.4 20.3 0.15 12.4 4.4 3.6 1 1 2 3 3 3 0 Tup N-terminal HisKA_7TM PF16927.5 GAX29113.1 - 8.2e-05 22.7 14.0 0.0005 20.2 13.3 2.4 1 1 2 3 3 3 1 N-terminal 7TM region of histidine kinase DctQ PF04290.12 GAX29113.1 - 0.018 15.0 2.2 0.018 15.0 2.2 2.6 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF4051 PF13260.6 GAX29113.1 - 0.12 12.1 1.8 16 5.3 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) UCR_6-4kD PF08997.10 GAX29113.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.4 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein FA_desaturase PF00487.24 GAX29113.1 - 1.8 8.3 7.2 0.29 10.9 1.4 2.2 1 1 1 2 2 2 0 Fatty acid desaturase zinc_ribbon_6 PF14599.6 GAX29114.1 - 1.8e-18 66.3 0.5 1.8e-18 66.3 0.5 3.9 2 1 1 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 GAX29114.1 - 5e-15 55.7 14.0 5e-15 55.7 14.0 5.1 2 2 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 GAX29114.1 - 4.5e-09 36.5 9.4 4.5e-09 36.5 9.4 5.2 5 1 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 GAX29114.1 - 3.5e-05 23.7 8.0 3.5e-05 23.7 8.0 5.5 5 3 1 6 6 6 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAX29114.1 - 0.0011 18.9 3.3 0.0011 18.9 3.3 5.6 6 0 0 6 6 6 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAX29114.1 - 0.0012 18.7 8.3 0.0012 18.7 8.3 5.5 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX29114.1 - 0.0017 18.1 6.8 0.0017 18.1 6.8 5.6 3 2 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 GAX29114.1 - 0.0043 17.0 3.8 0.0043 17.0 3.8 3.3 3 1 0 4 4 4 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 GAX29114.1 - 0.0065 16.3 3.7 0.0065 16.3 3.7 5.5 3 2 2 5 5 5 3 Prokaryotic RING finger family 4 Rubredoxin_2 PF18073.1 GAX29114.1 - 0.048 13.4 0.5 0.048 13.4 0.5 6.5 8 1 0 8 8 8 0 Rubredoxin metal binding domain VKOR PF07884.14 GAX29115.1 - 1.1e-23 83.7 7.5 1.1e-23 83.7 7.5 1.9 2 0 0 2 2 2 1 Vitamin K epoxide reductase family Thioredoxin PF00085.20 GAX29115.1 - 0.019 14.9 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 GAX29115.1 - 0.029 14.5 0.1 0.46 10.6 0.0 2.2 1 1 0 2 2 2 0 Thioredoxin MRG PF05712.13 GAX29116.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 MRG DAO PF01266.24 GAX29117.1 - 2.4e-57 195.1 0.0 5.8e-37 128.1 0.1 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Fer2_BFD PF04324.15 GAX29117.1 - 2.6e-10 40.5 3.3 6.6e-10 39.2 3.3 1.7 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 GAX29117.1 - 2.1e-05 25.0 0.3 0.33 11.5 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAX29117.1 - 7.1e-05 22.2 0.3 0.0049 16.1 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAX29117.1 - 0.00018 20.9 0.0 0.02 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX29117.1 - 0.005 15.9 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAX29117.1 - 0.011 15.9 0.1 0.028 14.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 GAX29117.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Mito_carr PF00153.27 GAX29118.1 - 6.5e-39 131.8 6.3 1.8e-13 50.2 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Longin PF13774.6 GAX29118.1 - 0.06 13.4 0.1 0.24 11.5 0.1 1.9 2 0 0 2 2 2 0 Regulated-SNARE-like domain HMG-CoA_red PF00368.18 GAX29119.1 - 2.2e-130 435.0 7.0 3e-130 434.5 7.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase ATLF PF07737.11 GAX29119.1 - 0.018 14.3 0.3 0.029 13.7 0.3 1.2 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain Pex24p PF06398.11 GAX29119.1 - 0.15 11.0 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin SNF2_N PF00176.23 GAX29120.1 - 3.6e-57 193.7 0.0 6e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAX29120.1 - 9.9e-16 58.1 0.0 3.2e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.8 GAX29120.1 - 1.9e-08 34.0 0.0 8.2e-08 31.9 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) DEAD PF00270.29 GAX29120.1 - 3e-05 23.8 0.0 0.00035 20.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase HEAT PF02985.22 GAX29120.1 - 0.0002 21.3 5.2 0.89 10.0 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat SWI2_SNF2 PF18766.1 GAX29120.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase CLASP_N PF12348.8 GAX29120.1 - 0.041 13.4 0.2 0.17 11.4 0.2 2.1 2 0 0 2 2 2 0 CLASP N terminal Med9 PF07544.13 GAX29122.1 - 0.0011 19.0 4.8 0.0093 16.0 3.2 2.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Glyco_hydro_115 PF15979.5 GAX29122.1 - 0.035 13.6 0.2 0.072 12.5 0.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 PspB PF06667.12 GAX29122.1 - 4.1 7.5 10.8 14 5.9 0.5 3.6 3 0 0 3 3 3 0 Phage shock protein B ASFV_J13L PF05568.11 GAX29123.1 - 0.015 15.0 0.2 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DP PF08781.10 GAX29124.1 - 2.3e-31 108.5 1.2 4.5e-31 107.6 1.2 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 GAX29124.1 - 3.7e-23 81.4 0.5 9.7e-23 80.0 0.5 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Octopine_DH PF02317.17 GAX29126.1 - 3.1e-28 98.7 0.0 4.8e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain ApbA PF02558.16 GAX29126.1 - 0.00017 21.3 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 GAX29126.1 - 0.002 18.7 0.0 0.0053 17.3 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 GAX29126.1 - 0.0039 16.2 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 GAX29126.1 - 0.04 13.9 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 GAX29126.1 - 0.18 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Bombolitin PF08096.11 GAX29126.1 - 0.43 11.0 1.7 23 5.5 0.0 2.6 2 0 0 2 2 2 0 Bombolitin family DAO PF01266.24 GAX29127.1 - 3.7e-28 99.1 0.0 3.8e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX29127.1 - 0.00028 20.2 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX29127.1 - 0.00035 20.6 0.1 0.47 10.4 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding Dor1 PF04124.12 GAX29127.1 - 0.01 14.6 0.2 0.015 14.0 0.2 1.2 1 0 0 1 1 1 0 Dor1-like family Amino_oxidase PF01593.24 GAX29127.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase E1-E2_ATPase PF00122.20 GAX29128.1 - 1.1e-47 161.9 1.2 2.3e-47 160.8 1.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAX29128.1 - 6.8e-27 95.1 0.0 3.1e-26 93.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAX29128.1 - 0.00057 20.3 10.8 0.0029 18.0 0.0 5.1 6 1 0 6 6 6 1 Heavy-metal-associated domain HAD PF12710.7 GAX29128.1 - 0.002 18.6 0.0 2.3 8.6 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAX29128.1 - 0.004 16.9 2.6 0.086 12.6 0.4 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ninjurin PF04923.12 GAX29128.1 - 0.038 13.9 1.1 0.089 12.7 1.1 1.6 1 0 0 1 1 1 0 Ninjurin ACCA PF03255.14 GAX29129.1 - 0.003 17.5 0.1 0.66 9.8 0.1 2.1 2 0 0 2 2 2 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit JmjC PF02373.22 GAX29130.1 - 1.5e-36 125.3 1.1 2e-36 124.9 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase S1 PF00575.23 GAX29131.1 - 1e-05 25.7 0.1 1e-05 25.7 0.1 2.0 2 0 0 2 2 2 1 S1 RNA binding domain NOA36 PF06524.12 GAX29131.1 - 0.037 13.4 8.8 0.05 12.9 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein Smg4_UPF3 PF03467.15 GAX29131.1 - 0.066 13.2 1.4 0.11 12.5 1.4 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family Curto_V2 PF07325.11 GAX29131.1 - 0.096 12.6 4.9 0.21 11.5 4.9 1.6 1 0 0 1 1 1 0 Curtovirus V2 protein RNA_pol_3_Rpc31 PF11705.8 GAX29131.1 - 0.37 11.0 13.9 0.62 10.3 13.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HemY_N PF07219.13 GAX29131.1 - 0.82 9.9 3.5 13 6.0 0.0 2.4 2 0 0 2 2 2 0 HemY protein N-terminus Astro_capsid_p PF12226.8 GAX29131.1 - 8.9 5.3 9.4 15 4.6 9.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Fe-S_biosyn PF01521.20 GAX29132.1 - 4.1e-16 59.2 0.0 5.5e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DHO_dh PF01180.21 GAX29133.1 - 2.5e-55 187.8 0.0 3e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 GAX29133.1 - 0.00017 20.7 0.2 0.00051 19.2 0.0 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 GAX29133.1 - 0.0018 17.7 0.1 0.0031 17.0 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 GAX29133.1 - 0.043 13.0 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase Iso_dh PF00180.20 GAX29134.1 - 2.6e-21 76.1 0.0 5.9e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_1 PF00036.32 GAX29134.1 - 2.2e-09 36.2 0.5 5.8e-09 34.9 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 GAX29134.1 - 3.5e-07 29.4 0.2 8.9e-07 28.1 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAX29134.1 - 4.5e-06 26.2 0.1 1.9e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAX29134.1 - 0.00012 22.5 0.1 0.00037 20.9 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAX29134.1 - 0.00022 21.0 0.2 0.00069 19.4 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair Agenet PF05641.12 GAX29135.1 - 4.7e-05 23.8 1.9 0.0018 18.7 0.1 3.1 3 0 0 3 3 3 1 Agenet domain Mei5 PF10376.9 GAX29135.1 - 0.058 13.3 4.7 0.075 12.9 4.2 1.3 1 1 0 1 1 1 0 Double-strand recombination repair protein PAP_assoc PF03828.19 GAX29136.1 - 0.00087 19.5 1.1 0.0033 17.6 1.1 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase SHOCT PF09851.9 GAX29136.1 - 0.062 13.1 0.1 0.2 11.5 0.1 1.9 1 0 0 1 1 1 0 Short C-terminal domain DUF1877 PF08974.10 GAX29136.1 - 0.093 12.8 0.9 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) Carn_acyltransf PF00755.20 GAX29137.1 - 2.1e-168 561.6 0.0 2.4e-168 561.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Na_H_Exchanger PF00999.21 GAX29138.1 - 1e-52 179.2 36.7 1.5e-52 178.7 36.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family XRN_M PF17846.1 GAX29139.1 - 6.9e-129 430.6 1.4 5.4e-87 292.6 0.1 2.3 1 1 1 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 GAX29139.1 - 5.8e-98 327.1 0.0 1.5e-97 325.8 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF5117 PF17148.4 GAX29140.1 - 0.069 13.0 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5117) Pannexin_like PF12534.8 GAX29140.1 - 7.9 5.5 7.0 13 4.7 7.0 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 PPR_2 PF13041.6 GAX29141.1 - 4.2e-34 116.5 6.3 5.6e-06 26.4 0.0 11.8 6 5 5 11 11 11 9 PPR repeat family PPR_1 PF12854.7 GAX29141.1 - 8.3e-22 76.6 2.3 0.0035 17.0 0.0 10.9 13 1 0 13 13 13 4 PPR repeat PPR_3 PF13812.6 GAX29141.1 - 7.5e-21 74.0 10.4 8e-07 29.0 0.0 8.6 7 4 4 11 11 11 4 Pentatricopeptide repeat domain PPR PF01535.20 GAX29141.1 - 1.3e-18 65.9 22.8 0.0006 19.9 0.0 11.6 13 1 0 13 13 13 4 PPR repeat PPR_long PF17177.4 GAX29141.1 - 6.6e-15 55.1 3.4 0.00019 20.8 0.1 5.6 2 2 5 7 7 7 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 GAX29141.1 - 0.00037 20.9 0.0 0.31 11.5 0.0 3.6 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) DUF4003 PF13170.6 GAX29141.1 - 0.086 12.2 1.3 5.3 6.3 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF4003) TPR_7 PF13176.6 GAX29141.1 - 0.2 11.8 0.5 1e+02 3.3 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_8 PF01501.20 GAX29142.1 - 3.1e-05 23.6 0.0 3.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GAX29142.1 - 0.021 14.3 0.5 0.028 13.8 0.5 1.5 1 1 0 1 1 1 0 Glucosyltransferase 24 PPR_2 PF13041.6 GAX29143.1 - 2.8e-34 117.1 1.5 5.3e-05 23.3 0.0 10.6 5 3 5 10 10 10 8 PPR repeat family PPR_1 PF12854.7 GAX29143.1 - 1.1e-22 79.4 3.0 0.0022 17.6 0.0 11.2 14 0 0 14 14 14 4 PPR repeat PPR_3 PF13812.6 GAX29143.1 - 1.5e-22 79.4 3.5 7.7e-06 25.9 0.0 8.7 8 3 0 9 9 9 5 Pentatricopeptide repeat domain PPR PF01535.20 GAX29143.1 - 4.1e-19 67.4 22.8 0.00055 20.0 0.0 11.6 12 1 0 12 12 12 4 PPR repeat PPR_long PF17177.4 GAX29143.1 - 2.2e-12 46.8 3.7 9.4e-05 21.9 0.0 5.8 1 1 3 5 5 5 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 GAX29143.1 - 0.00018 21.9 0.0 0.045 14.2 0.0 3.6 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 GAX29143.1 - 0.15 13.0 5.8 40 5.4 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Glyco_transf_8 PF01501.20 GAX29144.1 - 1.4e-16 60.8 0.2 2.8e-16 59.8 0.2 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GAX29144.1 - 0.00011 21.7 0.3 0.00025 20.5 0.3 1.7 1 1 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_34 PF05637.12 GAX29144.1 - 0.03 14.0 0.2 0.054 13.2 0.2 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Cullin PF00888.22 GAX29145.1 - 3.9e-160 534.5 11.5 5.2e-160 534.1 11.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAX29145.1 - 1.4e-24 85.9 0.7 1.4e-24 85.9 0.7 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain TraA PF05513.11 GAX29145.1 - 0.023 15.0 0.1 0.071 13.4 0.1 1.8 1 0 0 1 1 1 0 TraA ATC_hydrolase PF14196.6 GAX29145.1 - 0.059 14.1 0.3 3.1 8.6 0.2 2.9 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Pectate_lyase_3 PF12708.7 GAX29145.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Pectate lyase superfamily protein NusB PF01029.18 GAX29146.1 - 0.16 12.2 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 NusB family adh_short_C2 PF13561.6 GAX29147.1 - 1.3e-33 116.5 0.0 1.9e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX29147.1 - 1.2e-22 80.4 0.0 1.8e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX29147.1 - 8.3e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 GAX29147.1 - 0.00033 20.4 0.1 0.00054 19.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 GAX29147.1 - 0.026 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rossmann-like PF10727.9 GAX29147.1 - 0.038 13.8 0.3 0.072 13.0 0.3 1.4 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_2 PF07992.14 GAX29147.1 - 0.067 12.4 0.1 0.097 11.9 0.1 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YjeF_N PF03853.15 GAX29147.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 GAX29147.1 - 0.13 12.1 0.1 0.28 11.0 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAX29147.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.6 GAX29147.1 - 0.15 12.0 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding FAD_oxidored PF12831.7 GAX29147.1 - 0.25 10.6 0.9 0.33 10.3 0.9 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase E3_UFM1_ligase PF09743.9 GAX29148.1 - 1.4e-09 38.0 0.0 2.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 His_Phos_2 PF00328.22 GAX29149.1 - 5.9e-19 68.7 0.0 2e-15 57.0 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) mTERF PF02536.14 GAX29152.1 - 7e-45 153.3 4.1 8.3e-22 77.5 0.3 3.2 1 1 2 3 3 3 3 mTERF DUF1732 PF08340.11 GAX29152.1 - 0.044 13.8 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) ArsC PF03960.15 GAX29152.1 - 0.47 10.5 3.8 20 5.3 0.0 3.7 4 0 0 4 4 4 0 ArsC family Ank_2 PF12796.7 GAX29154.1 - 2.9e-23 82.3 0.4 2.1e-15 57.0 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX29154.1 - 7e-20 71.1 0.9 7.7e-08 32.7 0.0 3.9 2 2 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX29154.1 - 3.2e-17 60.8 0.2 5.4e-05 23.3 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAX29154.1 - 6.5e-15 54.8 2.5 3.3e-05 24.1 0.0 4.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAX29154.1 - 2.1e-14 53.4 1.0 0.00041 20.6 0.1 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) C2 PF00168.30 GAX29155.1 - 6.4e-25 87.4 0.0 7e-10 39.1 0.0 3.3 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.5 GAX29155.1 - 4.1e-11 42.7 0.1 7e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain V-SNARE_C PF12352.8 GAX29156.1 - 2.3e-06 27.8 2.5 2.3e-06 27.8 2.5 2.2 3 0 0 3 3 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAX29156.1 - 5.1e-06 26.3 1.7 1.6e-05 24.7 1.4 2.0 1 1 1 2 2 2 1 Sec20 DUF4407 PF14362.6 GAX29156.1 - 0.00027 20.4 7.0 0.00035 20.0 7.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) V-SNARE PF05008.15 GAX29156.1 - 0.0011 19.3 4.6 0.0011 19.3 4.6 2.6 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus RPW8 PF05659.11 GAX29156.1 - 0.0014 18.3 5.6 0.23 11.1 0.9 2.3 2 0 0 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Val_tRNA-synt_C PF10458.9 GAX29156.1 - 0.0083 16.4 0.2 0.0083 16.4 0.2 3.3 4 0 0 4 4 4 1 Valyl tRNA synthetase tRNA binding arm DUF5435 PF17503.2 GAX29156.1 - 0.015 15.0 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Rhamno_transf PF11316.8 GAX29156.1 - 0.025 14.0 1.0 0.036 13.4 1.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase EMP24_GP25L PF01105.24 GAX29156.1 - 0.1 12.5 3.6 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD XhlA PF10779.9 GAX29156.1 - 0.17 12.1 11.1 0.29 11.3 2.0 3.1 3 0 0 3 3 3 0 Haemolysin XhlA UPF0242 PF06785.11 GAX29156.1 - 0.17 11.9 10.1 0.51 10.4 0.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PEP-utilisers_N PF05524.13 GAX29156.1 - 0.36 11.0 9.0 3.1 8.0 0.7 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Chordopox_A13L PF05961.11 GAX29156.1 - 0.42 10.9 1.8 1.1 9.6 0.7 2.1 1 1 1 2 2 2 0 Chordopoxvirus A13L protein SNARE PF05739.19 GAX29156.1 - 0.45 10.6 9.4 0.13 12.2 5.7 2.2 2 1 0 2 2 2 0 SNARE domain PhaP_Bmeg PF09602.10 GAX29156.1 - 0.56 10.1 6.4 0.35 10.8 0.9 2.4 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Utp11 PF03998.13 GAX29156.1 - 0.7 9.8 9.7 1.3 8.9 9.8 1.4 1 1 0 1 1 1 0 Utp11 protein CLZ PF16526.5 GAX29156.1 - 1 9.8 9.2 0.4 11.1 1.4 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cauli_AT PF03233.13 GAX29156.1 - 1.5 8.7 9.0 0.4 10.6 1.5 2.5 2 1 0 2 2 2 0 Aphid transmission protein TSNAXIP1_N PF15739.5 GAX29156.1 - 2.2 8.7 9.5 1.6 9.2 1.9 2.5 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF641 PF04859.12 GAX29156.1 - 3.1 8.1 11.1 13 6.2 3.5 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TMEM192 PF14802.6 GAX29156.1 - 3.5 6.7 7.3 2.8 7.0 0.7 2.1 1 1 1 2 2 2 0 TMEM192 family Enkurin PF13864.6 GAX29156.1 - 4.6 7.8 11.6 0.85 10.1 2.9 2.4 2 1 0 2 2 2 0 Calmodulin-binding FUSC PF04632.12 GAX29156.1 - 4.7 5.6 4.7 1.7 7.0 1.1 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF4200 PF13863.6 GAX29156.1 - 7.1 7.1 15.3 8 6.9 4.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) GDC-P PF02347.16 GAX29157.1 - 6.3e-186 618.4 0.3 6.7e-175 582.0 0.0 3.1 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 GAX29157.1 - 3.2e-07 29.7 0.5 6.4e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAX29157.1 - 6.3e-05 22.4 0.1 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase RNase_H2-Ydr279 PF09468.10 GAX29157.1 - 0.084 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Pyridoxal_deC PF00282.19 GAX29157.1 - 0.12 11.1 0.0 9.6 4.8 0.0 2.3 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain MMR_HSR1_Xtn PF16897.5 GAX29159.1 - 6.4e-37 125.8 0.3 1.1e-36 125.1 0.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 GAX29159.1 - 1.3e-20 73.6 0.1 3.5e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAX29159.1 - 1e-10 41.4 0.0 2.2e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 GAX29159.1 - 2.4e-09 37.1 0.0 4.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 GAX29159.1 - 0.0004 20.5 0.1 1.1 9.3 0.0 2.6 3 0 0 3 3 3 2 Dynamin family MeaB PF03308.16 GAX29159.1 - 0.012 14.6 0.1 0.021 13.8 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1192 PF06698.11 GAX29159.1 - 0.013 15.6 1.1 0.61 10.2 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) AIG1 PF04548.16 GAX29159.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Phage_GP20 PF06810.11 GAX29159.1 - 0.057 13.2 0.6 0.094 12.5 0.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 ABC_tran PF00005.27 GAX29159.1 - 0.076 13.5 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 GAX29159.1 - 0.087 12.7 1.6 6.8 6.6 0.0 2.9 4 0 0 4 4 4 0 RsgA GTPase Roc PF08477.13 GAX29159.1 - 0.093 13.0 0.1 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF4355 PF14265.6 GAX29159.1 - 0.42 10.9 2.5 6.9 6.9 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Glyco_hydro_1 PF00232.18 GAX29160.1 - 2.5e-157 523.9 4.4 9e-156 518.8 2.2 2.3 3 0 0 3 3 3 2 Glycosyl hydrolase family 1 Glyco_hydro_18 PF00704.28 GAX29160.1 - 4.4e-09 36.5 0.5 2e-08 34.3 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 HABP4_PAI-RBP1 PF04774.15 GAX29161.1 - 1.9e-13 51.3 8.3 1.9e-13 51.3 8.3 3.7 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Dicty_REP PF05086.12 GAX29161.1 - 1.6 6.6 2.2 2.1 6.2 2.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fucose_iso_C PF02952.17 GAX29163.1 - 0.14 11.8 0.1 0.61 9.8 0.1 1.9 2 0 0 2 2 2 0 L-fucose isomerase, C-terminal domain DUF4943 PF16301.5 GAX29163.1 - 0.15 12.1 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4943) PI-PLC-X PF00388.19 GAX29164.1 - 0.0048 16.5 0.1 0.0088 15.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Varsurf_PPLC PF03490.13 GAX29164.1 - 0.015 15.2 0.0 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C Sad1_UNC PF07738.13 GAX29164.1 - 0.054 13.5 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Gpr1_Fun34_YaaH PF01184.19 GAX29165.1 - 8e-12 45.2 10.1 1.3e-11 44.5 10.1 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF547 PF04784.14 GAX29166.1 - 4.9e-09 36.3 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Flavodoxin_1 PF00258.25 GAX29167.1 - 1.2e-18 67.7 0.1 1.5e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin Glyco_tran_WecB PF03808.13 GAX29167.1 - 0.07 13.1 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MctB PF11382.8 GAX29167.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Flavodoxin_1 PF00258.25 GAX29169.1 - 1.5e-19 70.6 0.0 6.7e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 Flavodoxin CBFD_NFYB_HMF PF00808.23 GAX29170.1 - 6.7e-21 74.3 0.3 1.8e-20 73.0 0.3 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAX29170.1 - 3e-12 47.0 0.9 3e-12 47.0 0.9 2.6 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 GAX29170.1 - 0.15 12.1 3.0 0.46 10.5 0.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Dicty_REP PF05086.12 GAX29170.1 - 2.1 6.2 8.3 2.8 5.8 8.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DotU PF09850.9 GAX29170.1 - 2.4 7.8 10.4 6.5 6.4 5.3 2.6 2 1 0 2 2 2 0 Type VI secretion system protein DotU Exo5 PF09810.9 GAX29170.1 - 2.8 7.4 6.8 3.9 6.9 6.8 1.4 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease CENP-O PF09496.10 GAX29170.1 - 3.9 7.4 8.1 5.3 7.0 3.9 2.1 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component Exostosin PF03016.15 GAX29171.1 - 1e-19 70.9 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Exostosin family WD40 PF00400.32 GAX29172.1 - 6e-32 109.2 8.1 7.4e-08 32.9 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX29172.1 - 6.6e-10 39.2 0.0 0.00056 20.2 0.0 4.8 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAX29172.1 - 6.1e-08 31.8 3.1 0.022 13.4 2.0 4.3 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAX29172.1 - 5.9e-05 22.2 3.3 0.64 8.9 0.0 3.9 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAX29172.1 - 0.0009 17.9 0.0 0.012 14.2 0.0 2.4 2 1 1 3 3 3 1 Cytochrome D1 heme domain eIF2A PF08662.11 GAX29172.1 - 0.0069 16.3 1.4 8.5 6.2 0.0 3.9 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 GAX29172.1 - 0.012 14.3 0.2 0.86 8.3 0.0 3.2 4 1 0 4 4 4 0 Nup133 N terminal like PQQ_3 PF13570.6 GAX29172.1 - 0.26 11.8 4.8 6.2 7.5 0.0 3.8 5 1 1 6 6 6 0 PQQ-like domain DnaJ PF00226.31 GAX29173.1 - 5e-16 58.6 3.9 6.3e-16 58.3 1.5 2.4 2 0 0 2 2 2 1 DnaJ domain DUF4523 PF15023.6 GAX29173.1 - 0.0012 18.7 1.0 0.0026 17.6 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RRM_1 PF00076.22 GAX29173.1 - 0.013 15.3 0.3 0.059 13.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4748 PF15932.5 GAX29173.1 - 2.8 7.8 10.0 5.9 6.7 6.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) zf-RING_2 PF13639.6 GAX29174.1 - 2.5e-11 43.7 10.4 2.5e-11 43.7 10.4 2.5 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 GAX29174.1 - 5.4e-08 33.0 12.9 3.5e-07 30.4 12.9 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAX29174.1 - 2.7e-07 30.3 9.0 2.7e-07 30.3 9.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAX29174.1 - 1.1e-06 28.6 4.2 1.1e-06 28.6 4.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAX29174.1 - 1.3e-06 28.1 8.8 3.3e-06 26.7 8.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAX29174.1 - 1.5e-05 24.7 8.9 1.5e-05 24.7 8.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAX29174.1 - 6.7e-05 22.7 5.4 6.7e-05 22.7 5.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAX29174.1 - 0.00015 21.6 7.7 0.00015 21.6 7.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAX29174.1 - 0.00021 21.3 7.5 0.00083 19.4 7.5 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAX29174.1 - 0.0048 17.0 8.6 0.0048 17.0 8.6 2.3 2 1 0 2 2 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAX29174.1 - 0.0097 15.5 7.4 0.0097 15.5 7.4 2.3 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAX29174.1 - 0.035 14.0 7.6 0.11 12.4 7.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 GAX29174.1 - 1.1 9.4 12.5 0.51 10.5 9.1 2.2 2 0 0 2 2 2 0 RING-variant domain zf-Nse PF11789.8 GAX29174.1 - 6 6.8 7.9 3 7.7 5.1 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MS_channel PF00924.18 GAX29175.1 - 1.2e-14 54.4 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Sigma54_AID PF00309.20 GAX29175.1 - 0.077 12.9 0.2 0.48 10.3 0.5 2.1 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) His_Phos_1 PF00300.22 GAX29176.1 - 5.1e-27 94.8 0.2 9.2e-27 94.0 0.0 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Acetyltransf_1 PF00583.25 GAX29177.1 - 1.1e-11 45.0 0.0 1.6e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX29177.1 - 2.3e-09 37.2 0.1 3.4e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX29177.1 - 1.6e-07 31.6 0.2 3.6e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX29177.1 - 1.9e-07 31.0 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 GAX29177.1 - 0.0026 17.3 0.0 0.0036 16.8 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 GAX29177.1 - 0.0027 17.8 0.1 0.0053 16.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAX29177.1 - 0.07 13.3 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase KdpD PF02702.17 GAX29178.1 - 0.089 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain MS_channel PF00924.18 GAX29179.1 - 7.6e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF5558 PF17713.1 GAX29179.1 - 0.2 12.0 0.5 2.2 8.6 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5558) LRR_6 PF13516.6 GAX29180.1 - 0.00017 21.3 1.7 2.3 8.5 0.1 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 GAX29180.1 - 0.072 13.7 0.1 65 4.7 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat STI1 PF17830.1 GAX29181.1 - 7.5e-07 29.0 2.9 1.5e-05 24.9 4.1 2.3 2 0 0 2 2 2 1 STI1 domain SAP PF02037.27 GAX29181.1 - 0.12 12.2 1.6 11 5.9 0.0 3.1 3 0 0 3 3 3 0 SAP domain Bystin PF05291.11 GAX29182.1 - 4.5e-121 403.6 0.4 7e-121 403.0 0.4 1.2 1 0 0 1 1 1 1 Bystin Chalcone_3 PF16036.5 GAX29183.1 - 1.4e-12 48.0 0.0 1.2e-11 45.0 0.0 1.9 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone_2 PF16035.5 GAX29183.1 - 0.0099 15.7 0.1 3.1 7.5 0.1 2.1 1 1 1 2 2 2 2 Chalcone isomerase like Pro_isomerase PF00160.21 GAX29185.1 - 7.1e-38 130.4 0.0 8e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Branch PF02485.21 GAX29186.1 - 5e-21 75.3 0.2 7.8e-21 74.7 0.2 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme adh_short PF00106.25 GAX29187.1 - 3.2e-50 170.3 1.3 4.9e-50 169.7 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX29187.1 - 2.8e-41 141.6 2.3 3.9e-41 141.1 1.8 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX29187.1 - 8.4e-13 48.6 1.8 1.2e-12 48.1 1.8 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAX29187.1 - 4.3e-05 23.5 2.2 5.7e-05 23.1 2.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAX29187.1 - 0.00018 21.1 1.1 0.00056 19.5 1.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAX29187.1 - 0.00069 19.7 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 GAX29187.1 - 0.00086 18.5 0.9 0.0012 18.0 0.9 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 GAX29187.1 - 0.0037 16.6 0.4 0.0068 15.8 0.3 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAX29187.1 - 0.04 13.8 0.6 0.065 13.1 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aminotran_5 PF00266.19 GAX29188.1 - 1.1e-17 64.1 0.0 3.2e-10 39.5 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-V SHMT PF00464.19 GAX29188.1 - 0.031 12.9 0.0 0.08 11.5 0.0 1.5 2 0 0 2 2 2 0 Serine hydroxymethyltransferase Thioredoxin PF00085.20 GAX29189.1 - 3.5e-07 30.1 0.0 7.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phasin PF05597.11 GAX29189.1 - 0.0012 18.9 0.9 0.19 11.8 0.0 2.8 3 0 0 3 3 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) DIM1 PF02966.16 GAX29189.1 - 0.043 13.6 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 NOA36 PF06524.12 GAX29189.1 - 8.6 5.6 8.5 2.3 7.5 5.4 1.6 2 0 0 2 2 2 0 NOA36 protein ATG22 PF11700.8 GAX29190.1 - 2.6e-15 56.0 33.6 2.8e-11 42.8 20.8 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAX29190.1 - 1.1e-10 40.9 34.3 1.1e-10 40.9 34.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ParB_C PF18064.1 GAX29191.1 - 0.089 13.0 0.2 0.49 10.6 0.1 2.1 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal TIM PF00121.18 GAX29192.1 - 4.3e-59 199.8 0.0 4.8e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase 7tm_3 PF00003.22 GAX29193.1 - 3.2e-18 66.3 17.3 5.4e-18 65.6 17.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Pardaxin PF07425.11 GAX29193.1 - 0.093 12.4 0.2 0.27 10.9 0.2 1.8 1 0 0 1 1 1 0 Pardaxin GARS_A PF01071.19 GAX29194.1 - 5.4e-78 261.2 0.0 9.7e-78 260.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 GAX29194.1 - 1.7e-41 141.9 0.1 5.6e-41 140.3 0.0 2.0 2 0 0 2 2 2 1 Formyl transferase AIRS_C PF02769.22 GAX29194.1 - 2.7e-36 125.1 0.0 6.7e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 GAX29194.1 - 3.7e-29 101.4 0.4 1.4e-28 99.5 0.4 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 GAX29194.1 - 1.5e-21 76.4 1.0 4.3e-21 75.0 0.4 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 GAX29194.1 - 2.5e-14 53.7 1.1 9.4e-14 51.8 1.1 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 GAX29194.1 - 1.5e-05 25.1 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GAX29194.1 - 0.00047 19.7 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Peptidase_S8 PF00082.22 GAX29195.1 - 3.2e-14 52.9 0.9 3.1e-13 49.6 0.9 2.0 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAX29195.1 - 0.0058 17.3 0.0 0.0099 16.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF4025 PF13217.6 GAX29195.1 - 0.3 11.0 1.8 9.7 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4025) Peptidase_S8 PF00082.22 GAX29196.1 - 2.1e-39 135.6 5.2 2.4e-38 132.1 5.2 2.0 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAX29196.1 - 0.018 15.7 1.3 0.042 14.5 1.3 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I9 Mon1 PF03164.14 GAX29197.1 - 1.1e-26 93.9 0.0 1.4e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Beta_helix PF13229.6 GAX29198.1 - 1.2e-07 31.7 6.4 1.3e-05 25.1 2.1 2.6 1 1 1 2 2 2 2 Right handed beta helix region DUF1565 PF07602.11 GAX29198.1 - 0.14 11.5 3.1 2.6 7.3 0.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1565) Gal-3-0_sulfotr PF06990.11 GAX29199.1 - 9.3e-09 34.6 6.8 1.7e-06 27.2 2.2 2.9 1 1 1 2 2 2 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 GAX29199.1 - 1.5e-06 28.3 0.2 3.4e-06 27.2 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase family GST_N_3 PF13417.6 GAX29200.1 - 5.7e-23 81.1 0.4 1.2e-12 48.0 0.0 3.6 4 0 0 4 4 4 3 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAX29200.1 - 2.1e-13 50.2 0.0 8.1e-08 32.4 0.0 3.5 3 1 0 3 3 3 2 Glutaredoxin GST_N_2 PF13409.6 GAX29200.1 - 0.00042 20.6 0.0 0.1 12.9 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 GAX29200.1 - 0.017 15.4 0.0 0.7 10.2 0.0 2.4 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein ABC_membrane PF00664.23 GAX29201.1 - 3.2e-58 197.6 18.5 2.2e-31 109.5 8.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX29201.1 - 1.9e-34 119.1 0.1 3.8e-24 85.7 0.0 3.5 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 GAX29201.1 - 2.2e-06 27.3 2.6 0.057 12.9 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAX29201.1 - 0.00032 21.0 0.4 0.16 12.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAX29201.1 - 0.00033 20.6 2.5 3.3 7.4 0.1 4.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 GAX29201.1 - 0.00073 19.3 1.7 3.5 7.3 0.0 3.8 3 1 1 4 4 4 2 IstB-like ATP binding protein AAA_13 PF13166.6 GAX29201.1 - 0.00077 18.2 0.1 0.0012 17.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAX29201.1 - 0.0009 19.7 0.4 0.29 11.5 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain DEAD PF00270.29 GAX29201.1 - 0.0017 18.1 0.1 1.7 8.3 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 GAX29201.1 - 0.003 17.4 0.1 0.21 11.3 0.0 2.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 GAX29201.1 - 0.0042 16.8 0.2 1.9 8.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GAX29201.1 - 0.0064 16.1 2.7 2 7.9 0.0 3.7 3 1 1 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 GAX29201.1 - 0.023 14.6 0.3 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 GAX29201.1 - 0.029 14.4 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 GAX29201.1 - 0.042 12.9 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 GAX29201.1 - 0.068 13.2 0.1 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 GAX29201.1 - 0.073 13.2 1.0 0.21 11.6 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 GAX29201.1 - 0.074 13.2 0.1 0.59 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAX29201.1 - 0.11 12.0 0.1 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 GAX29201.1 - 0.11 13.0 0.1 5.6 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 GAX29201.1 - 0.12 11.2 0.1 0.46 9.4 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain AAA_11 PF13086.6 GAX29201.1 - 0.27 11.0 0.2 6.1 6.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain MatE PF01554.18 GAX29203.1 - 7.4e-16 58.2 24.9 1.2e-10 41.3 7.7 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAX29203.1 - 2.3e-09 37.4 7.4 2.3e-09 37.4 7.4 3.7 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain AJAP1_PANP_C PF15298.6 GAX29203.1 - 0.094 12.9 0.4 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus PetG PF02529.15 GAX29203.1 - 1.3 8.9 3.6 0.53 10.2 0.5 1.9 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 PQ-loop PF04193.14 GAX29204.1 - 1.5e-07 31.1 0.3 0.0017 18.1 0.1 3.0 3 0 0 3 3 3 2 PQ loop repeat FGFR3_TM PF18123.1 GAX29204.1 - 0.17 11.4 0.6 0.6 9.7 0.1 2.2 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain Lipase_GDSL_2 PF13472.6 GAX29205.1 - 9.5e-08 32.6 0.0 1.2e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAX29205.1 - 2.7e-05 24.2 0.0 3.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WD40 PF00400.32 GAX29206.1 - 1.2e-11 45.0 4.9 0.0022 18.8 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX29206.1 - 0.018 15.3 0.0 23 5.4 0.0 3.7 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Antimicrobial22 PF16047.5 GAX29206.1 - 0.095 12.6 1.0 0.19 11.6 1.0 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide NOA36 PF06524.12 GAX29206.1 - 0.62 9.3 12.4 1 8.6 12.4 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 GAX29206.1 - 1.2 8.5 14.4 1.9 7.9 14.4 1.2 1 0 0 1 1 1 0 SDA1 CLU PF13236.6 GAX29207.1 - 6.1e-65 219.2 0.0 1.3e-64 218.1 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAX29207.1 - 5.9e-34 117.6 0.7 6.2e-33 114.3 0.0 3.0 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 GAX29207.1 - 1.6e-10 41.1 3.4 0.00054 20.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat CLU_N PF15044.6 GAX29207.1 - 0.00023 21.4 1.1 0.17 12.3 0.0 3.8 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TERB2 PF15101.6 GAX29207.1 - 0.45 10.5 6.9 0.44 10.6 4.8 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 STAT_int PF02865.17 GAX29208.1 - 0.2 12.1 0.0 0.56 10.7 0.0 1.7 2 0 0 2 2 2 0 STAT protein, protein interaction domain Kelch_1 PF01344.25 GAX29211.1 - 1.9e-33 113.8 1.4 5.9e-08 32.2 0.4 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAX29211.1 - 3.3e-30 102.9 1.9 2.6e-07 30.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAX29211.1 - 3.3e-29 100.4 0.5 7.2e-06 25.9 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 GAX29211.1 - 7.8e-28 95.8 1.1 1.4e-05 25.2 0.0 6.6 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 GAX29211.1 - 1e-27 95.8 18.3 5.3e-06 26.6 0.0 8.1 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_4 PF13418.6 GAX29211.1 - 3e-25 88.0 8.2 0.0001 22.3 0.3 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 GAX29211.1 - 4.4e-25 88.1 0.8 1.4e-24 86.4 0.2 2.0 1 1 1 2 2 2 1 BTB/POZ domain TPT PF03151.16 GAX29212.1 - 4.9e-99 331.3 19.5 6.2e-99 331.0 19.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX29212.1 - 8.6e-08 32.4 32.0 0.0003 20.9 9.8 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 GAX29212.1 - 0.0025 17.1 16.9 0.0043 16.3 16.2 1.6 1 1 1 2 2 2 1 UAA transporter family DDOST_48kD PF03345.14 GAX29212.1 - 0.17 10.7 0.4 0.33 9.7 0.4 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta NAD_binding_8 PF13450.6 GAX29213.1 - 0.011 15.9 0.3 0.078 13.2 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAX29213.1 - 0.054 12.2 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 GAX29213.1 - 0.068 12.2 0.1 0.37 9.8 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Aha1_N PF09229.11 GAX29214.1 - 6.3e-26 91.2 0.4 6.3e-26 91.2 0.4 2.6 3 1 0 3 3 2 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.17 GAX29214.1 - 2.3e-19 67.8 3.4 4.7e-08 32.5 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAX29214.1 - 5.2e-17 60.9 2.8 9e-08 31.6 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAX29214.1 - 2.9e-11 42.8 5.9 0.00044 19.9 0.4 3.4 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 GAX29214.1 - 1.3e-08 34.9 5.0 0.00011 22.7 0.9 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX29214.1 - 1.5e-08 35.2 2.6 3.2e-05 24.5 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAX29214.1 - 3e-08 33.7 1.1 1.3e-07 31.6 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX29214.1 - 2.3e-07 30.5 0.4 0.07 13.4 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX29214.1 - 5e-07 29.9 4.2 0.0096 16.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX29214.1 - 6.2e-07 29.4 0.3 0.033 14.2 0.0 2.8 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 GAX29214.1 - 2.2e-06 28.0 2.9 2.2e-06 28.0 2.9 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX29214.1 - 4.7e-05 23.7 0.3 4.7e-05 23.7 0.3 3.4 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAX29214.1 - 0.00032 20.5 0.7 0.018 15.1 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAX29214.1 - 0.00048 20.3 1.2 0.013 15.9 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAX29214.1 - 0.0011 19.2 0.7 0.0032 17.7 0.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAX29214.1 - 0.0012 18.7 4.3 0.17 11.8 0.5 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAX29214.1 - 0.99 10.2 3.9 1.1 10.0 1.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Coilin_N PF15862.5 GAX29214.1 - 2.1 8.1 0.0 2.1 8.1 0.0 3.6 2 1 0 3 3 3 0 Coilin N-terminus UCH PF00443.29 GAX29215.1 - 4.8e-41 141.0 0.0 7.6e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAX29215.1 - 4.5e-12 46.2 0.1 3.7e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PseudoU_synth_2 PF00849.22 GAX29216.1 - 9.1e-31 107.1 0.0 2.4e-30 105.7 0.0 1.8 2 1 0 2 2 2 1 RNA pseudouridylate synthase Abhydrolase_6 PF12697.7 GAX29217.1 - 1.1e-06 29.5 0.0 2.3e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAX29217.1 - 7.9e-06 25.3 0.2 2.1e-05 23.9 0.2 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 GAX29217.1 - 0.0057 16.2 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Glyco_hydro_97 PF10566.9 GAX29217.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 Pro_Al_protease PF02983.14 GAX29217.1 - 0.27 11.3 0.2 0.27 11.3 0.2 1.7 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Pescadillo_N PF06732.11 GAX29218.1 - 3.8e-59 200.5 0.0 3.8e-59 200.5 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 GAX29218.1 - 3.9e-05 24.0 0.1 0.00032 21.0 0.0 2.6 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain GCIP PF13324.6 GAX29218.1 - 1.4 8.5 21.6 1.5 8.3 9.0 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting MttA_Hcf106 PF02416.16 GAX29219.1 - 1.3e-07 30.9 4.0 2e-07 30.3 4.0 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family PL48 PF15903.5 GAX29220.1 - 0.0042 16.1 0.2 0.0048 15.9 0.2 1.0 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 Neur_chan_memb PF02932.16 GAX29221.1 - 0.13 12.3 1.4 0.2 11.7 1.1 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tox-ODYAM1 PF15642.6 GAX29221.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Biotin_lipoyl PF00364.22 GAX29227.1 - 2e-05 24.3 0.1 0.0012 18.7 0.0 2.6 3 0 0 3 3 3 2 Biotin-requiring enzyme zf-MYND PF01753.18 GAX29228.1 - 5.7e-08 32.7 16.8 1.3e-07 31.5 16.8 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 GAX29228.1 - 1.3 8.9 7.5 0.47 10.4 3.9 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-MYND PF01753.18 GAX29229.1 - 7.1e-08 32.4 14.6 1.9e-07 31.1 14.6 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 GAX29230.1 - 4.6e-07 29.8 14.4 9.4e-07 28.8 14.4 1.5 1 0 0 1 1 1 1 MYND finger CbiD PF01888.17 GAX29231.1 - 0.064 12.5 0.2 0.083 12.2 0.2 1.2 1 0 0 1 1 1 0 CbiD zf-MYND PF01753.18 GAX29232.1 - 2.4e-08 33.9 14.3 2.4e-08 33.9 14.3 2.1 2 0 0 2 2 2 1 MYND finger PolC_DP2 PF03833.13 GAX29232.1 - 0.038 11.9 3.2 0.05 11.5 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Adeno_terminal PF02459.15 GAX29232.1 - 0.077 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein zf-Mss51 PF13824.6 GAX29232.1 - 2.8 8.1 11.3 0.073 13.2 4.2 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 GAX29233.1 - 6.3e-08 32.6 13.7 1.3e-07 31.6 13.7 1.6 1 0 0 1 1 1 1 MYND finger CTK3_C PF12350.8 GAX29233.1 - 0.056 13.6 0.4 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus DUF3016 PF11454.8 GAX29233.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Kinetochor_Ybp2 PF08568.10 GAX29233.1 - 0.14 10.6 0.1 0.24 9.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Peptidase_S28 PF05577.12 GAX29234.1 - 2.8e-51 174.7 0.0 4.2e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Mpv17_PMP22 PF04117.12 GAX29235.1 - 4.5e-13 49.2 0.6 4.5e-13 49.2 0.6 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family HTH_57 PF18679.1 GAX29236.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 ThcOx helix turn helix domain DUF2183 PF09949.9 GAX29237.1 - 6.2e-05 23.3 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Rad60-SLD PF11976.8 GAX29239.1 - 1e-13 50.9 0.2 7.6e-13 48.1 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAX29239.1 - 0.0002 21.1 0.1 0.00073 19.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family CDC45 PF02724.14 GAX29239.1 - 2.4 6.3 16.9 3.6 5.8 16.9 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GAX29239.1 - 3.5 6.9 20.5 1.2 8.4 16.7 1.9 2 0 0 2 2 2 0 BUD22 CDC27 PF09507.10 GAX29239.1 - 9.8 5.4 21.8 15 4.8 21.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TPT PF03151.16 GAX29240.1 - 8.3e-36 123.8 17.3 1.1e-35 123.5 17.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAX29240.1 - 5.5e-05 22.5 15.8 5.5e-05 22.5 15.8 2.2 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.20 GAX29240.1 - 0.00011 22.4 26.2 0.0075 16.4 0.8 3.4 3 0 0 3 3 3 2 EamA-like transporter family TFB6 PF17110.5 GAX29240.1 - 2.6 7.8 4.6 1.4 8.6 0.7 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH HMG_box PF00505.19 GAX29242.1 - 7.3e-16 58.3 0.4 1.5e-15 57.4 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX29242.1 - 1.4e-08 35.2 0.2 4.4e-08 33.6 0.2 1.9 1 0 0 1 1 1 1 HMG-box domain Nefa_Nip30_N PF10187.9 GAX29242.1 - 4.5 7.7 8.0 19 5.7 1.4 2.7 3 0 0 3 3 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 HSF_DNA-bind PF00447.17 GAX29243.1 - 2.7e-18 66.4 0.1 6e-18 65.2 0.0 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding rve PF00665.26 GAX29244.1 - 1.4e-14 54.3 0.0 6.6e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GAX29244.1 - 6.7e-05 22.6 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 GAX29244.1 - 0.00088 19.1 0.4 0.0022 17.8 0.1 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain SAP PF02037.27 GAX29244.1 - 0.097 12.5 0.1 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 SAP domain RVT_2 PF07727.14 GAX29245.1 - 1.9e-41 142.3 0.2 3.5e-41 141.5 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAX29245.1 - 2.4e-14 53.6 0.0 7e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GAX29245.1 - 3.1e-08 33.3 15.4 5e-05 23.2 0.9 2.9 3 0 0 3 3 3 2 Zinc knuckle gag_pre-integrs PF13976.6 GAX29245.1 - 0.0002 21.2 1.6 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 GAX29245.1 - 0.00081 19.1 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 GAX29245.1 - 0.03 14.3 12.2 0.16 12.0 5.6 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GAX29245.1 - 0.32 10.8 6.5 1.7 8.4 0.4 2.8 2 0 0 2 2 2 0 Zinc knuckle RVT_2 PF07727.14 GAX29246.1 - 2.6e-40 138.6 0.0 4.9e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX29246.1 - 0.00017 21.5 4.4 0.00046 20.1 4.4 1.8 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 GAX29246.1 - 0.049 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 GAG-pre-integrase domain Pkinase PF00069.25 GAX29249.1 - 4.4e-35 121.3 0.0 8.8e-35 120.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX29249.1 - 4.7e-33 114.6 0.0 7.6e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX29249.1 - 0.0026 16.6 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAX29249.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 GAX29250.1 - 3.8e-39 134.7 0.0 5.5e-38 130.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX29250.1 - 7.6e-39 133.5 0.0 1.1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAX29250.1 - 0.059 12.1 1.0 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase HSF_DNA-bind PF00447.17 GAX29251.1 - 1.2e-19 70.7 0.1 1.7e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Globin PF00042.22 GAX29253.1 - 2.2e-09 37.8 0.0 5.2e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Globin Globin PF00042.22 GAX29254.1 - 9.3e-11 42.3 0.0 1.1e-09 38.8 0.0 2.0 2 0 0 2 2 2 1 Globin CBM_6 PF03422.15 GAX29257.1 - 3e-11 43.7 0.9 3e-05 24.3 0.3 3.3 2 1 0 3 3 3 3 Carbohydrate binding module (family 6) TPR_1 PF00515.28 GAX29258.1 - 4.6e-07 29.4 6.2 0.0019 17.9 1.7 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX29258.1 - 1.2e-05 25.1 11.0 0.0036 17.3 1.8 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX29258.1 - 9.3e-05 22.4 2.2 0.062 13.5 0.9 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX29258.1 - 0.00012 21.9 0.3 0.1 12.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX29258.1 - 0.00096 18.8 1.0 0.16 11.7 0.0 2.9 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 GAX29258.1 - 0.0011 19.6 5.3 1.1 10.0 1.1 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAX29258.1 - 0.0047 17.2 4.6 0.16 12.3 1.8 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAX29258.1 - 0.031 14.9 6.3 0.16 12.6 1.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX29258.1 - 0.031 14.8 4.3 0.21 12.1 1.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX29258.1 - 0.073 13.0 5.2 0.43 10.5 2.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX29258.1 - 0.28 12.1 2.9 24 6.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CBM_6 PF03422.15 GAX29259.1 - 6.3e-26 91.1 0.3 9.5e-12 45.3 0.0 3.2 3 1 0 3 3 3 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX29259.1 - 6.5e-07 29.5 0.0 0.0012 19.0 0.0 2.7 3 0 0 3 3 3 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX29259.1 - 7.8e-07 29.4 0.6 0.032 14.5 0.0 3.4 3 1 0 3 3 3 2 Carbohydrate binding module (family 35) Oxidored_q6 PF01058.22 GAX29260.1 - 8.7e-24 83.8 0.1 1.3e-23 83.3 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit CBM_6 PF03422.15 GAX29261.1 - 1.2e-13 51.5 2.2 3.5e-11 43.5 0.1 2.3 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) CBM_35 PF16990.5 GAX29261.1 - 0.0049 17.1 1.0 2.1 8.6 0.0 3.0 2 2 0 2 2 2 2 Carbohydrate binding module (family 35) CBM_6 PF03422.15 GAX29262.1 - 1e-27 96.9 2.7 6.8e-11 42.6 0.0 3.5 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX29262.1 - 1.4e-15 57.4 0.5 4.8e-08 33.1 0.0 3.5 3 0 0 3 3 3 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX29262.1 - 5.5e-05 23.4 0.9 0.58 10.4 0.0 3.2 3 0 0 3 3 3 2 Carbohydrate binding module (family 35) CBM_6 PF03422.15 GAX29263.1 - 1.3e-12 48.1 1.5 1.2e-09 38.5 0.1 2.9 2 1 0 2 2 2 2 Carbohydrate binding module (family 6) CBM_35 PF16990.5 GAX29263.1 - 0.00021 21.5 0.4 0.2 11.9 0.0 2.7 2 1 0 2 2 2 2 Carbohydrate binding module (family 35) Kin17_mid PF10357.9 GAX29263.1 - 0.023 14.6 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein CBM_6 PF03422.15 GAX29264.1 - 1.9e-22 79.9 0.0 2.3e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX29264.1 - 1.4e-07 31.6 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX29264.1 - 2.4e-05 24.6 0.0 3.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) CBM_6 PF03422.15 GAX29265.1 - 9.4e-43 145.5 4.0 1e-21 77.5 0.1 3.4 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX29265.1 - 1.2e-12 47.9 0.5 9.1e-07 29.0 0.0 3.0 3 0 0 3 3 3 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX29265.1 - 0.00016 21.9 1.2 0.22 11.8 0.1 3.6 3 0 0 3 3 3 2 Carbohydrate binding module (family 35) MCM PF00493.23 GAX29266.1 - 2.2e-80 269.0 0.0 4.3e-80 268.0 0.0 1.4 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 GAX29266.1 - 3.2e-23 81.9 1.2 1.2e-22 80.1 0.2 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 GAX29266.1 - 2e-22 79.4 1.2 4.6e-22 78.2 1.2 1.6 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 GAX29266.1 - 1.9e-11 43.8 1.6 1.9e-09 37.2 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAX29266.1 - 4.6e-10 39.6 0.1 1.1e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAX29266.1 - 1.6e-07 31.2 0.2 4.9e-06 26.4 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAX29266.1 - 3.4e-06 27.0 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAX29266.1 - 0.00072 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 GAX29266.1 - 0.0079 16.6 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX29266.1 - 0.015 15.7 0.0 0.044 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 GAX29266.1 - 0.093 13.1 0.3 6.1 7.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAX29266.1 - 0.13 11.1 0.0 0.32 9.9 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Amidase_2 PF01510.25 GAX29266.1 - 0.18 12.3 0.1 5.4 7.5 0.0 2.4 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase E1-E2_ATPase PF00122.20 GAX29267.1 - 1.1e-40 139.1 0.6 1.1e-40 139.1 0.6 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX29267.1 - 5.1e-39 133.9 0.3 5.1e-39 133.9 0.3 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAX29267.1 - 1e-13 51.2 0.0 1.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAX29267.1 - 1e-12 47.5 0.0 2.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 GAX29267.1 - 2.7e-12 47.4 3.5 9e-10 39.2 0.3 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAX29267.1 - 0.016 15.0 1.5 0.25 11.0 1.3 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4265 PF14085.6 GAX29267.1 - 0.16 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Tic22 PF04278.12 GAX29268.1 - 1.4e-07 31.1 0.2 2.4e-06 27.1 0.2 2.1 1 1 0 1 1 1 1 Tic22-like family Sugar_tr PF00083.24 GAX29269.1 - 1.2e-06 27.7 8.3 1.2e-06 27.7 7.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter KaiA PF07688.12 GAX29269.1 - 0.042 14.0 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 KaiA C-terminal domain Methyltransf_25 PF13649.6 GAX29270.1 - 0.0082 16.8 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX29270.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 GAX29271.1 - 2.5e-52 175.4 0.6 8.6e-18 64.7 0.2 3.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAX29271.1 - 1.6e-25 88.8 1.9 1.2e-07 31.8 0.1 5.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAX29271.1 - 9e-24 83.5 2.0 2.2e-11 44.0 0.0 5.0 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX29271.1 - 3.3e-22 76.2 3.3 0.00021 21.5 0.1 6.0 5 1 1 6 6 6 5 Ankyrin repeat Ank PF00023.30 GAX29271.1 - 4.6e-19 67.9 4.8 4.6e-06 26.8 0.7 5.4 5 0 0 5 5 5 5 Ankyrin repeat DUF1843 PF08898.10 GAX29271.1 - 0.035 14.6 0.2 0.85 10.2 0.0 3.2 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) GATase_7 PF13537.6 GAX29271.1 - 0.074 13.0 0.0 0.93 9.4 0.0 2.2 1 1 1 2 2 2 0 Glutamine amidotransferase domain Aldo_ket_red PF00248.21 GAX29272.1 - 8.1e-15 54.8 0.0 3e-14 52.9 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1974 PF09317.11 GAX29273.1 - 7.4e-45 153.7 0.1 3.6e-44 151.4 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 GAX29273.1 - 7e-14 52.5 0.0 1.5e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAX29273.1 - 1.6e-08 34.9 1.3 1.6e-08 34.9 1.3 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAX29273.1 - 8.3e-06 25.9 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Spo0A_C PF08769.11 GAX29273.1 - 0.058 13.5 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal PseudoU_synth_2 PF00849.22 GAX29275.1 - 8e-15 55.3 0.0 1.7e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase Lumazine_bd_2 PF12893.7 GAX29276.1 - 7.4e-11 42.7 0.0 5.3e-07 30.3 0.0 3.4 2 2 0 2 2 2 2 Putative lumazine-binding V-ATPase_G_2 PF16999.5 GAX29277.1 - 0.011 16.1 20.7 0.27 11.7 6.1 3.1 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF2459 PF09601.10 GAX29277.1 - 0.11 12.4 1.1 0.12 12.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) DUF1640 PF07798.11 GAX29277.1 - 0.11 12.6 14.7 4 7.4 14.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) XRN1_D1 PF18332.1 GAX29277.1 - 0.26 11.0 4.3 0.046 13.5 0.7 1.5 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D1 domain YliH PF10799.8 GAX29277.1 - 0.39 10.6 3.6 0.41 10.6 0.8 2.3 1 1 1 2 2 2 0 Biofilm formation protein (YliH/bssR) DUF4407 PF14362.6 GAX29277.1 - 1.1 8.6 13.7 1.8 7.9 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ApoO PF09769.9 GAX29277.1 - 1.4 8.9 4.8 0.63 10.0 0.7 2.4 2 1 0 2 2 2 0 Apolipoprotein O PHA_gran_rgn PF09650.10 GAX29277.1 - 2.6 8.4 6.4 21 5.5 0.4 2.8 1 1 2 3 3 3 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) PEP-utilisers_N PF05524.13 GAX29277.1 - 3.2 7.9 13.4 0.76 10.0 1.9 3.4 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal Peptidase_M43 PF05572.13 GAX29278.1 - 1.4e-09 38.1 5.0 4.7e-08 33.1 5.0 2.4 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAX29278.1 - 0.00014 22.1 0.1 0.00028 21.1 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX29278.1 - 0.00033 21.2 0.0 0.0006 20.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX29278.1 - 0.001 18.8 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAX29278.1 - 0.0065 16.3 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 GAX29278.1 - 0.096 12.6 0.2 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like SecA_PP_bind PF01043.20 GAX29278.1 - 0.16 12.7 0.1 0.28 11.8 0.1 1.4 1 0 0 1 1 1 0 SecA preprotein cross-linking domain Aminotran_3 PF00202.21 GAX29279.1 - 2e-107 359.4 0.0 2.6e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAX29279.1 - 0.0071 15.7 0.0 0.014 14.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SR-25 PF10500.9 GAX29280.1 - 5.2e-29 101.5 22.0 8.3e-29 100.8 22.0 1.3 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein LAP1C PF05609.12 GAX29280.1 - 4.7 6.2 16.0 5.4 6.0 16.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PPR_2 PF13041.6 GAX29282.1 - 5.6e-13 48.9 0.0 2.6e-09 37.1 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 GAX29282.1 - 1.2e-08 34.7 0.1 4.6e-05 23.4 0.0 4.0 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.7 GAX29282.1 - 1.7e-06 27.6 0.0 0.0046 16.6 0.0 3.3 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 GAX29282.1 - 2.1e-05 24.5 0.3 0.0067 16.5 0.0 3.4 2 1 2 4 4 4 2 Pentatricopeptide repeat domain TPR_14 PF13428.6 GAX29282.1 - 0.011 16.5 2.7 11 7.1 0.1 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 GAX29282.1 - 0.08 13.4 1.1 0.22 12.0 0.1 2.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain CHAD PF05235.14 GAX29282.1 - 0.57 10.1 3.6 0.3 11.0 0.5 1.9 2 0 0 2 2 2 0 CHAD domain GTP_EFTU PF00009.27 GAX29283.1 - 1.6e-30 106.1 6.5 4.8e-29 101.3 6.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAX29283.1 - 5.4e-23 81.1 2.5 8.7e-23 80.5 0.7 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 GAX29283.1 - 5.3e-12 45.8 0.3 1.4e-11 44.5 0.3 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 GAX29283.1 - 1.4e-08 34.4 0.0 3.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 GAX29283.1 - 4.8e-07 29.4 0.9 1.3e-06 28.0 0.9 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAX29283.1 - 1.6e-06 28.1 2.2 0.00015 21.7 0.1 2.6 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 GAX29283.1 - 6.3e-06 25.7 0.3 2.6e-05 23.7 0.3 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAX29283.1 - 1.1e-05 25.1 0.2 1.7e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 GAX29283.1 - 2.6e-05 23.7 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 GAX29283.1 - 0.00013 22.3 8.3 0.004 17.5 0.1 3.9 4 0 0 4 4 4 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 GAX29283.1 - 0.0006 19.7 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 GAX29283.1 - 0.0056 16.7 0.2 0.53 10.3 0.0 2.6 1 1 1 2 2 2 1 Dynamin family DUF742 PF05331.11 GAX29283.1 - 0.0064 16.3 0.1 0.02 14.7 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF742) MMR_HSR1_Xtn PF16897.5 GAX29283.1 - 0.0094 16.0 0.3 0.024 14.6 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Roc PF08477.13 GAX29283.1 - 0.011 16.0 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NTP_transf_3 PF12804.7 GAX29283.1 - 0.04 14.3 0.4 0.24 11.8 0.0 2.3 2 0 0 2 2 2 0 MobA-like NTP transferase domain AIG1 PF04548.16 GAX29283.1 - 0.053 12.8 0.1 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 AIG1 family PduV-EutP PF10662.9 GAX29283.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 GAX29283.1 - 0.2 12.1 0.0 0.47 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NBP1 PF08537.10 GAX29284.1 - 0.013 14.9 61.2 0.31 10.4 1.0 7.6 8 0 0 8 8 8 0 Fungal Nap binding protein NBP1 Branch PF02485.21 GAX29285.1 - 2.1e-19 70.0 0.6 1.1e-18 67.7 0.6 1.8 1 1 0 1 1 1 1 Core-2/I-Branching enzyme HD PF01966.22 GAX29286.1 - 7.9e-14 51.9 0.8 2e-13 50.6 0.8 1.7 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 GAX29286.1 - 0.00088 19.1 0.1 0.0018 18.0 0.1 1.5 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HDOD PF08668.12 GAX29286.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 HDOD domain PDEase_I PF00233.19 GAX29286.1 - 0.0029 17.4 0.3 0.0049 16.6 0.3 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-MYND PF01753.18 GAX29287.1 - 1.2e-06 28.4 3.4 3.9e-06 26.8 3.4 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 GAX29287.1 - 1 9.5 9.6 0.081 13.0 2.6 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Flavokinase PF01687.17 GAX29288.1 - 7.2e-31 106.8 0.0 1.1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Methyltransf_25 PF13649.6 GAX29288.1 - 6e-14 52.5 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX29288.1 - 2.4e-12 47.0 0.0 4.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX29288.1 - 2.2e-11 43.8 0.0 4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAX29288.1 - 2e-10 41.2 0.0 4.2e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAX29288.1 - 8.2e-10 39.3 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX29288.1 - 1.3e-06 27.9 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAX29288.1 - 2.3e-06 27.3 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAX29288.1 - 0.00046 20.2 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 GAX29288.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) UPF0020 PF01170.18 GAX29288.1 - 0.019 14.6 0.0 0.073 12.7 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF938 PF06080.12 GAX29288.1 - 0.048 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_10 PF05971.12 GAX29288.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase MetW PF07021.12 GAX29288.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Med28 PF11594.8 GAX29288.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 PCMT PF01135.19 GAX29288.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pyr_redox_2 PF07992.14 GAX29289.1 - 1.1e-42 146.3 0.2 1.5e-42 145.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAX29289.1 - 9.2e-17 61.3 0.0 1.2e-15 57.7 0.0 2.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAX29289.1 - 4.3e-14 52.8 0.9 1.1e-10 41.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX29289.1 - 0.00016 21.0 0.2 0.0052 16.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAX29289.1 - 0.00044 19.6 0.5 0.37 10.0 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAX29289.1 - 0.0009 18.9 0.3 0.0029 17.2 0.3 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAX29289.1 - 0.014 14.6 0.0 0.045 12.9 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 GAX29289.1 - 0.016 15.1 1.2 3 7.7 0.1 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 GAX29289.1 - 0.14 12.4 0.6 3.3 8.0 0.2 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_trans_4_5 PF16994.5 GAX29289.1 - 0.15 11.7 0.1 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl-transferase family 4 ApbA PF02558.16 GAX29289.1 - 0.45 10.1 1.7 6.3 6.4 0.0 3.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Ribosomal_L4 PF00573.22 GAX29290.1 - 1.3e-52 178.3 0.1 1.7e-52 178.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family TssR PF17643.1 GAX29291.1 - 0.085 10.8 2.3 0.13 10.2 2.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssR PPR_2 PF13041.6 GAX29292.1 - 2e-28 98.3 10.5 3.6e-10 39.9 0.1 7.4 5 3 2 8 8 8 6 PPR repeat family PPR_1 PF12854.7 GAX29292.1 - 2.4e-19 68.7 10.5 0.00028 20.5 0.1 10.0 10 1 0 10 10 10 5 PPR repeat PPR_3 PF13812.6 GAX29292.1 - 1.4e-18 66.7 0.1 4e-07 30.0 0.0 5.6 5 1 1 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.20 GAX29292.1 - 2.4e-18 65.0 17.1 1e-05 25.4 0.1 10.2 11 1 0 11 11 11 5 PPR repeat PPR_long PF17177.4 GAX29292.1 - 4.5e-11 42.5 0.2 5.5e-06 25.9 0.1 3.2 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP Coatomer_E PF04733.14 GAX29292.1 - 0.0094 15.4 0.1 0.033 13.6 0.1 1.9 1 0 0 1 1 1 1 Coatomer epsilon subunit Ku_PK_bind PF08785.11 GAX29292.1 - 0.082 13.1 0.0 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 Ku C terminal domain like Toxin_YhaV PF11663.8 GAX29292.1 - 0.087 12.9 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system RsbU_N PF08673.10 GAX29292.1 - 0.091 12.9 0.2 4.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain ABC_membrane PF00664.23 GAX29293.1 - 7e-81 271.9 17.1 1.1e-41 143.3 2.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAX29293.1 - 4.1e-36 124.5 0.0 2.6e-34 118.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 GAX29293.1 - 5.7e-10 39.0 0.1 0.0002 20.9 0.0 2.6 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 GAX29293.1 - 3.1e-05 24.1 1.1 0.75 10.1 1.0 3.6 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GAX29293.1 - 0.028 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF2207 PF09972.9 GAX29293.1 - 0.038 12.7 1.7 0.21 10.3 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2417 PF10329.9 GAX29293.1 - 0.072 12.5 0.3 0.35 10.2 0.0 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Zeta_toxin PF06414.12 GAX29293.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 GAX29293.1 - 0.087 12.6 0.3 0.23 11.2 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAX29293.1 - 0.58 9.9 2.5 3.8 7.2 0.3 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_membrane PF00664.23 GAX29294.1 - 6.2e-42 144.1 4.5 8.3e-41 140.4 4.5 2.0 1 1 1 2 2 2 2 ABC transporter transmembrane region DUF2207 PF09972.9 GAX29294.1 - 0.086 11.6 0.0 0.086 11.6 0.0 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) ABC_membrane PF00664.23 GAX29295.1 - 3.5e-37 128.6 2.9 4.4e-37 128.2 2.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region CytB6-F_Fe-S PF08802.10 GAX29295.1 - 2.5 8.2 10.5 0.13 12.3 1.2 2.9 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit SET PF00856.28 GAX29296.1 - 3.9e-11 43.6 0.0 0.00014 22.3 0.0 3.6 3 1 1 4 4 4 2 SET domain Glyco_transf_28 PF03033.20 GAX29297.1 - 3.1e-18 66.1 0.0 6.8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAX29297.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAX29297.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain RTX PF02382.15 GAX29297.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Sporozoite_P67 PF05642.11 GAX29297.1 - 0.19 9.8 3.0 0.27 9.3 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen polyprenyl_synt PF00348.17 GAX29298.1 - 3.7e-66 222.8 0.1 5.5e-66 222.2 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 GAX29298.1 - 0.0022 17.6 0.1 0.0041 16.8 0.1 1.4 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 CBS PF00571.28 GAX29299.1 - 1.2e-25 89.7 1.0 3.3e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 CBS domain Peptidase_S29 PF02907.15 GAX29299.1 - 0.00035 20.3 0.1 0.00079 19.2 0.0 1.6 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Trypsin_2 PF13365.6 GAX29299.1 - 0.007 17.3 0.1 0.014 16.3 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.21 GAX29299.1 - 0.16 11.8 0.0 0.51 10.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Apolipoprotein PF01442.18 GAX29300.1 - 0.0073 16.2 12.0 0.77 9.6 11.6 3.2 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain ISG65-75 PF11727.8 GAX29300.1 - 0.01 15.1 5.1 0.01 15.1 5.1 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein YtxH PF12732.7 GAX29300.1 - 0.035 14.7 17.1 6.7e+03 -2.3 17.1 4.0 1 1 0 1 1 1 0 YtxH-like protein DUF1359 PF07097.11 GAX29300.1 - 0.15 12.3 1.3 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) DUF1018 PF06252.12 GAX29300.1 - 0.33 12.0 8.4 0.11 13.5 2.6 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1018) DUF4554 PF15091.6 GAX29300.1 - 3.3 6.5 6.8 2.4 7.0 5.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4554) DUF948 PF06103.11 GAX29300.1 - 6 7.2 5.2 4.3 7.7 0.6 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TIM PF00121.18 GAX29301.1 - 2.9e-82 275.7 0.0 3.4e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase 2OG-FeII_Oxy PF03171.20 GAX29302.1 - 8.8e-15 55.0 0.0 1.3e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cyclin_N PF00134.23 GAX29304.1 - 3.3e-29 101.2 0.2 3.5e-28 97.9 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAX29304.1 - 4e-23 81.8 0.1 8.8e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.19 GAX29304.1 - 0.17 12.0 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat PqiA PF04403.13 GAX29305.1 - 1.9e-06 27.8 16.4 0.00027 20.8 5.7 2.7 2 0 0 2 2 2 2 Paraquat-inducible protein A Abhydrolase_6 PF12697.7 GAX29306.1 - 4.7e-17 63.3 0.2 5.8e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAX29306.1 - 1.3e-16 61.0 0.1 4.5e-16 59.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAX29306.1 - 2.7e-11 43.2 0.0 9.5e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 GAX29306.1 - 0.00067 19.3 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 GAX29306.1 - 0.001 19.0 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 GAX29306.1 - 0.0084 16.0 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 GAX29306.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 GAX29306.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 GAX29306.1 - 0.077 12.5 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.14 GAX29306.1 - 0.11 11.2 0.0 0.42 9.3 0.0 1.8 2 0 0 2 2 2 0 Ndr family Acid_PPase PF12689.7 GAX29307.1 - 6e-42 143.3 0.0 7.1e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Cys_Met_Meta_PP PF01053.20 GAX29309.1 - 1.6e-81 273.8 0.0 2.6e-81 273.1 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAX29309.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Dynamin_N PF00350.23 GAX29312.1 - 8.4e-12 45.5 0.2 1e-09 38.7 0.0 2.7 2 1 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 GAX29312.1 - 0.0058 16.7 0.0 0.039 14.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 GAX29312.1 - 6.8 7.1 11.7 3.8 7.9 2.0 2.9 2 1 0 2 2 2 0 AAA domain DUF1275 PF06912.11 GAX29313.1 - 1.2e-12 48.2 16.2 1.7e-12 47.7 16.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Amidohydro_1 PF01979.20 GAX29314.1 - 8.9e-73 245.6 0.8 1.4e-72 244.9 0.8 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 GAX29314.1 - 1.8e-52 176.8 5.2 4e-52 175.7 5.2 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 GAX29314.1 - 6e-39 132.4 0.1 1.6e-38 131.0 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 GAX29314.1 - 3.2e-34 116.8 0.0 2.3e-33 114.1 0.0 2.2 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 GAX29314.1 - 4e-08 33.2 0.5 7e-06 25.8 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family cobW PF02492.19 GAX29315.1 - 3.6e-28 98.3 0.1 4.5e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 GAX29315.1 - 0.0002 20.5 0.1 0.017 14.1 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 GAX29315.1 - 0.0028 17.7 0.0 0.0061 16.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 GAX29315.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GAX29315.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 GAX29315.1 - 0.03 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAX29315.1 - 0.033 14.6 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GAX29315.1 - 0.043 14.3 0.0 0.054 14.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 GAX29315.1 - 0.085 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAX29315.1 - 0.13 11.2 0.0 0.25 10.4 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 GAX29315.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 GAX29315.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 GAX29315.1 - 0.17 11.0 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 GAX29315.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PUB PF09409.10 GAX29316.1 - 0.0001 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 PUB domain CDPS PF16715.5 GAX29316.1 - 0.025 14.2 0.7 0.042 13.5 0.7 1.4 1 0 0 1 1 1 0 Cyclodipeptide synthase CEND1 PF15677.5 GAX29316.1 - 0.2 12.2 2.8 0.28 11.7 2.8 1.2 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Thioredoxin_8 PF13905.6 GAX29317.1 - 2.3e-50 168.9 0.0 8.2e-25 87.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 GAX29317.1 - 1.2e-17 63.8 0.0 8.5e-08 32.1 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin AhpC-TSA PF00578.21 GAX29317.1 - 8.8e-14 51.5 0.0 6e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.6 GAX29317.1 - 1.6e-13 51.0 0.0 2.6e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Redoxin PF08534.10 GAX29317.1 - 4.1e-13 49.3 0.0 2.6e-06 27.2 0.0 2.5 2 1 0 2 2 2 2 Redoxin Thioredoxin_7 PF13899.6 GAX29317.1 - 3.4e-10 40.0 0.9 0.00012 22.2 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like TraF PF13728.6 GAX29317.1 - 9.1e-09 35.5 0.0 0.00079 19.3 0.0 2.9 2 1 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GAX29317.1 - 1.8e-06 27.8 0.0 0.036 13.8 0.0 3.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 GAX29317.1 - 5.2e-06 26.5 0.0 1.6e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain SCO1-SenC PF02630.14 GAX29317.1 - 0.00024 21.0 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 SCO1/SenC NADH_4Fe-4S PF10589.9 GAX29317.1 - 0.0052 16.8 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ARL17 PF15840.5 GAX29317.1 - 0.065 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 Glutaredoxin PF00462.24 GAX29317.1 - 0.16 12.2 3.9 10 6.4 0.2 3.6 3 1 0 3 3 2 0 Glutaredoxin Thioredoxin PF00085.20 GAX29318.1 - 9e-21 73.8 0.4 1.6e-20 73.0 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX29318.1 - 3.3e-08 33.8 1.7 0.0097 16.2 0.1 3.2 2 1 1 3 3 3 3 Thioredoxin-like Thioredoxin_2 PF13098.6 GAX29318.1 - 4.9e-07 30.2 3.4 1.6e-06 28.5 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAX29318.1 - 1e-06 28.7 0.9 8.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GAX29318.1 - 5.7e-05 22.9 0.2 0.00011 21.9 0.1 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 GAX29318.1 - 0.0014 18.7 0.3 0.0053 16.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like DUF4600 PF15372.6 GAX29318.1 - 0.0047 17.4 2.8 0.0065 16.9 2.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) Thioredoxin_3 PF13192.6 GAX29318.1 - 0.0057 16.7 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin domain LprI PF07007.12 GAX29318.1 - 0.021 15.5 5.6 0.034 14.8 5.6 1.3 1 0 0 1 1 1 0 Lysozyme inhibitor LprI TraF PF13728.6 GAX29318.1 - 0.025 14.4 0.6 0.097 12.5 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein PNK3P PF08645.11 GAX29318.1 - 0.034 13.9 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Glutaredoxin PF00462.24 GAX29318.1 - 0.076 13.2 1.7 0.11 12.7 0.3 2.0 2 1 0 2 2 2 0 Glutaredoxin ACCA PF03255.14 GAX29318.1 - 0.45 10.4 2.9 0.71 9.7 2.9 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HMG_box_2 PF09011.10 GAX29319.1 - 1e-10 42.0 4.6 2.8e-10 40.6 4.6 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 GAX29319.1 - 1.3e-10 41.5 9.1 1.8e-09 37.9 9.1 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box DUF2442 PF10387.9 GAX29320.1 - 0.027 14.8 0.1 0.27 11.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2442) Nmad3 PF18754.1 GAX29320.1 - 0.053 13.1 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Nucleotide modification associated domain 3 Cupin_8 PF13621.6 GAX29321.1 - 3.6e-24 85.9 0.0 6.6e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX29321.1 - 0.00062 19.3 0.1 0.0016 17.9 0.2 1.6 2 0 0 2 2 2 1 Cupin superfamily protein Cytochrom_B561 PF03188.16 GAX29322.1 - 0.051 13.7 1.8 0.096 12.8 1.8 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF4381 PF14316.6 GAX29322.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DnaJ-X PF14308.6 GAX29323.1 - 7.6e-31 107.2 8.9 1.3e-30 106.4 8.9 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAX29323.1 - 1.3e-21 76.4 2.7 3.1e-21 75.3 2.7 1.7 1 0 0 1 1 1 1 DnaJ domain EIAV_Rev PF11129.8 GAX29324.1 - 0.031 14.5 0.2 0.052 13.8 0.2 1.3 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus PVL_ORF50 PF07768.11 GAX29324.1 - 1.6 9.1 7.9 11 6.3 0.1 2.4 2 0 0 2 2 2 0 PVL ORF-50-like family YCII PF03795.14 GAX29325.1 - 9e-09 35.6 0.0 1.5e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 YCII-related domain DAO PF01266.24 GAX29326.1 - 6.6e-20 72.0 0.0 1.2e-19 71.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAX29326.1 - 6.8e-06 25.5 0.0 0.0051 16.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAX29326.1 - 6.6e-05 22.2 0.1 0.0012 18.0 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAX29326.1 - 0.00023 21.2 0.6 0.18 11.8 0.3 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAX29326.1 - 0.0011 18.2 1.7 0.44 9.5 0.2 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAX29326.1 - 0.0048 16.0 0.0 0.018 14.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 GAX29326.1 - 0.012 15.7 0.2 0.036 14.1 0.0 1.9 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 GAX29326.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 GAX29326.1 - 0.028 13.8 0.1 0.085 12.2 0.0 1.7 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.17 GAX29326.1 - 0.032 14.8 0.4 0.14 12.8 0.1 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 GAX29326.1 - 0.036 13.3 0.5 0.078 12.2 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 GAX29326.1 - 0.059 12.1 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 GAX29326.1 - 0.069 12.0 0.1 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 GAX29326.1 - 0.078 13.2 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAX29326.1 - 0.089 13.1 0.0 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 GAX29326.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 GAX29326.1 - 0.18 11.1 0.1 0.69 9.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cupin_8 PF13621.6 GAX29327.1 - 8e-22 78.2 0.0 1.3e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAX29327.1 - 6.5e-05 22.5 0.0 0.00035 20.1 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein TFIIS_C PF01096.18 GAX29328.1 - 5.7e-22 77.3 3.2 5.7e-22 77.3 3.2 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAX29328.1 - 9.6e-05 22.2 0.6 9.6e-05 22.2 0.6 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 GAX29328.1 - 0.00023 21.1 4.9 0.00024 21.0 1.3 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 GAX29328.1 - 0.0037 16.9 2.2 0.0037 16.9 2.2 1.8 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_10 PF10058.9 GAX29328.1 - 0.036 13.8 4.2 0.13 12.0 1.5 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-piccolo PF05715.13 GAX29328.1 - 0.29 11.3 0.3 0.29 11.3 0.3 2.6 2 2 0 2 2 2 0 Piccolo Zn-finger PhnA_Zn_Ribbon PF08274.12 GAX29328.1 - 1 9.3 11.5 0.84 9.6 4.1 3.2 2 2 1 3 3 3 0 PhnA Zinc-Ribbon Terminase_GpA PF05876.12 GAX29328.1 - 2 6.9 6.1 0.75 8.3 4.1 1.2 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) DNA_ligase_ZBD PF03119.16 GAX29328.1 - 2.1 8.5 8.4 4.1 7.5 0.2 2.9 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_4 PF13717.6 GAX29328.1 - 4.4 7.3 9.8 3.2 7.7 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbon domain DUF2387 PF09526.10 GAX29328.1 - 9.3 6.5 10.0 6.9 6.9 1.8 2.9 1 1 3 4 4 4 0 Probable metal-binding protein (DUF2387) Peptidase_M1 PF01433.20 GAX29329.1 - 6e-83 277.7 0.8 1.2e-82 276.8 0.3 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAX29329.1 - 1.1e-72 245.3 0.0 4.6e-72 243.2 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAX29329.1 - 5.6e-47 160.3 0.1 9.3e-47 159.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 GAX29329.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) SnoaL_2 PF12680.7 GAX29330.1 - 0.00017 22.2 0.0 0.00023 21.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 GAX29330.1 - 0.00063 19.5 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Lumazine_bd_2 PF12893.7 GAX29330.1 - 0.0035 18.0 0.0 0.0056 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative lumazine-binding COX17 PF05051.13 GAX29330.1 - 0.039 14.3 0.1 0.077 13.4 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Asp PF00026.23 GAX29331.1 - 4.3e-09 36.2 0.0 1.8e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease MutS_V PF00488.21 GAX29332.1 - 5.8e-59 199.3 0.0 1.4e-58 198.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAX29332.1 - 3.6e-28 99.1 2.8 5.7e-28 98.4 1.8 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 GAX29332.1 - 3e-05 24.3 0.0 9.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 GAX29332.1 - 0.0036 17.8 0.2 0.0087 16.6 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAX29332.1 - 0.019 14.7 0.0 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAX29332.1 - 0.037 13.8 0.3 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAX29332.1 - 0.056 14.0 0.0 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 GAX29332.1 - 0.081 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 GAX29332.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF4692 PF15763.5 GAX29332.1 - 1.1 9.7 5.9 2.4 8.6 5.9 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Peptidase_S64 PF08192.11 GAX29333.1 - 1.8 7.0 16.0 3 6.2 16.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 MBOAT_2 PF13813.6 GAX29334.1 - 8e-09 35.7 4.1 8e-09 35.7 4.1 2.4 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Methyltransf_16 PF10294.9 GAX29338.1 - 5.2e-07 29.6 0.0 1.5e-06 28.1 0.0 1.7 2 1 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAX29338.1 - 0.00014 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX29338.1 - 0.00045 20.0 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAX29338.1 - 0.0024 18.5 0.0 0.015 16.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX29338.1 - 0.014 16.1 0.0 0.07 13.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAX29338.1 - 0.14 12.9 0.0 1.1 10.1 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain TB PF00683.17 GAX29339.1 - 5.9 6.7 11.0 6.4 6.6 0.0 4.1 4 0 0 4 4 4 0 TB domain YccV-like PF08755.11 GAX29340.1 - 3.7e-27 94.7 1.1 8.9e-14 51.8 0.1 2.5 2 0 0 2 2 2 2 Hemimethylated DNA-binding protein YccV like TPR_1 PF00515.28 GAX29340.1 - 4.1e-13 48.5 0.0 1.9e-05 24.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX29340.1 - 1.6e-12 46.5 0.2 0.00063 19.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAX29340.1 - 2.7e-07 30.3 0.2 0.076 13.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAX29340.1 - 2.3e-06 27.6 0.0 0.043 14.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX29340.1 - 5.1e-06 27.0 0.1 0.00073 20.1 0.0 2.9 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX29340.1 - 1.1e-05 25.8 1.4 0.91 10.5 0.1 4.1 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAX29340.1 - 1.3e-05 25.6 4.1 9.7e-05 22.8 0.0 3.5 3 1 2 5 5 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX29340.1 - 1.4e-05 25.3 0.3 0.00088 19.5 0.0 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAX29340.1 - 0.00018 21.3 0.0 0.19 11.8 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAX29340.1 - 0.00028 20.5 0.3 2.8 7.7 0.0 4.3 3 2 2 5 5 5 2 TPR repeat TPR_6 PF13174.6 GAX29340.1 - 0.0007 20.1 0.7 1 10.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAX29340.1 - 0.0051 17.1 3.7 0.089 13.1 0.3 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4372 PF14294.6 GAX29340.1 - 0.032 14.4 0.3 0.16 12.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) Coatomer_E PF04733.14 GAX29340.1 - 0.074 12.5 0.2 0.17 11.3 0.2 1.6 1 0 0 1 1 1 0 Coatomer epsilon subunit U1snRNP70_N PF12220.8 GAX29340.1 - 0.11 13.1 0.6 0.62 10.7 0.1 2.5 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SMP_2 PF10144.9 GAX29340.1 - 0.15 11.7 0.4 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin HLH PF00010.26 GAX29340.1 - 0.18 11.8 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain ANAPC3 PF12895.7 GAX29340.1 - 0.24 11.6 2.3 0.99 9.7 0.0 2.9 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_M20 PF01546.28 GAX29341.1 - 6.3e-34 117.5 0.0 9.1e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAX29341.1 - 3.6e-11 43.0 0.0 1.1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain NAD_binding_8 PF13450.6 GAX29342.1 - 7.7e-11 42.1 1.4 5.1e-10 39.4 1.3 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX29342.1 - 8.1e-08 32.2 4.4 4.2e-07 29.9 4.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAX29342.1 - 1.2e-05 24.8 0.9 9.6e-05 21.8 0.0 1.9 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAX29342.1 - 0.0022 17.3 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAX29342.1 - 0.0038 17.2 0.1 0.0091 16.0 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAX29342.1 - 0.0044 16.4 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAX29342.1 - 0.0047 16.2 0.1 0.0069 15.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAX29342.1 - 0.013 16.1 0.7 0.029 14.9 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAX29342.1 - 0.017 14.0 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 GAX29342.1 - 0.02 14.0 0.5 0.022 13.9 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 GAX29342.1 - 0.13 11.3 1.2 0.19 10.8 1.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 GAX29342.1 - 0.45 9.1 2.1 0.7 8.5 2.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 7tm_3 PF00003.22 GAX29343.1 - 2.3e-27 96.2 17.5 3.2e-27 95.8 17.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Arm PF00514.23 GAX29345.1 - 1.1e-06 28.4 4.3 0.4 10.8 0.1 6.9 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAX29345.1 - 7.2e-05 23.1 9.1 0.52 10.7 0.1 4.9 2 1 1 4 4 4 3 HEAT repeats Atx10homo_assoc PF09759.9 GAX29345.1 - 0.013 15.5 5.0 0.77 9.8 0.1 4.3 3 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 GAX29345.1 - 0.022 14.7 11.4 0.37 10.7 0.0 4.1 3 2 1 4 4 4 0 Myosin-binding striated muscle assembly central HEAT PF02985.22 GAX29345.1 - 0.22 11.9 15.3 6.4 7.3 0.1 6.2 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 GAX29345.1 - 0.29 11.7 6.3 17 6.0 0.0 4.8 5 1 0 5 5 5 0 HEAT-like repeat HEAT_PBS PF03130.16 GAX29345.1 - 0.37 11.6 5.1 37 5.4 0.2 4.5 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat WD40 PF00400.32 GAX29346.1 - 1.8e-07 31.7 10.4 0.003 18.3 0.7 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 GAX29346.1 - 0.0042 17.5 1.2 0.054 14.0 0.4 3.1 3 0 0 3 3 3 1 PQQ-like domain ANAPC4_WD40 PF12894.7 GAX29346.1 - 0.012 15.9 1.7 2.9 8.3 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ccdc124 PF06244.12 GAX29347.1 - 1.6e-20 74.0 3.7 1.6e-20 74.0 3.7 2.3 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF2058 PF09831.9 GAX29347.1 - 3.6 7.7 28.0 2.9 8.0 17.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4972 PF16342.5 GAX29347.1 - 9 6.0 9.4 0.096 12.4 1.3 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4972) p450 PF00067.22 GAX29348.1 - 9.7e-72 242.2 0.1 1.3e-71 241.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_37 PF13744.6 GAX29348.1 - 0.074 13.0 0.4 0.2 11.7 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FliJ PF02050.16 GAX29348.1 - 0.19 11.9 1.3 0.26 11.5 0.3 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein V-SNARE_C PF12352.8 GAX29349.1 - 0.069 13.4 0.8 0.19 12.1 0.0 2.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus TPT PF03151.16 GAX29350.1 - 4.9e-84 282.1 11.1 5.9e-84 281.8 11.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAX29350.1 - 2.2e-06 27.9 28.7 0.00092 19.4 14.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family Glyco_transf_64 PF09258.10 GAX29352.1 - 1.1e-11 44.6 0.0 4.6e-10 39.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain Prp31_C PF09785.9 GAX29352.1 - 0.033 15.1 0.1 0.079 13.9 0.1 1.7 1 0 0 1 1 1 0 Prp31 C terminal domain HscB_4_cys PF18256.1 GAX29352.1 - 0.15 11.9 1.5 5.1 7.0 0.6 2.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif TPR_19 PF14559.6 GAX29353.1 - 0.027 15.0 5.2 5.2 7.7 0.7 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAX29353.1 - 0.045 13.8 2.6 0.055 13.5 0.2 2.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat RsgA_GTPase PF03193.16 GAX29353.1 - 0.24 11.3 1.1 0.4 10.6 0.4 1.7 2 0 0 2 2 2 0 RsgA GTPase TPR_14 PF13428.6 GAX29353.1 - 0.93 10.5 6.0 6.1 7.9 0.5 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAX29353.1 - 9.8 6.7 7.9 33 5.0 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Flavodoxin_1 PF00258.25 GAX29354.1 - 1.2e-21 77.5 0.3 1.5e-21 77.1 0.3 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 GAX29354.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.4 1 1 0 1 1 1 0 Flavodoxin domain Flavodoxin_3 PF12641.7 GAX29354.1 - 0.11 12.1 0.0 1.7 8.4 0.0 2.4 1 1 0 1 1 1 0 Flavodoxin domain FMN_red PF03358.15 GAX29354.1 - 0.13 12.0 0.0 0.58 9.9 0.0 2.2 1 1 0 1 1 1 0 NADPH-dependent FMN reductase LEM PF03020.15 GAX29354.1 - 0.15 11.6 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 LEM domain Flavodoxin_1 PF00258.25 GAX29355.1 - 5.5e-21 75.3 0.7 7.6e-21 74.8 0.7 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 GAX29355.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain FMN_red PF03358.15 GAX29355.1 - 0.089 12.5 0.1 0.41 10.4 0.0 2.2 3 1 0 3 3 3 0 NADPH-dependent FMN reductase Pkinase PF00069.25 GAX29358.1 - 7.4e-34 117.3 0.1 7.3e-33 114.1 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX29358.1 - 5.3e-14 52.1 0.0 1.6e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase ELFV_dehydrog_N PF02812.18 GAX29359.1 - 5.3e-36 123.4 0.0 1.1e-35 122.3 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 GAX29359.1 - 2.8e-33 115.6 0.1 7e-33 114.4 0.1 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 GAX29359.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.21 GAX29360.1 - 4.1e-16 59.2 0.0 1.5e-14 54.0 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAX29360.1 - 3.1e-10 40.0 0.0 1.2e-07 31.5 0.0 3.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase DCP2 PF05026.13 GAX29362.1 - 0.1 12.9 0.6 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Dcp2, box A domain adh_short_C2 PF13561.6 GAX29363.1 - 1.8e-63 214.2 2.3 2.4e-63 213.8 2.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAX29363.1 - 8.1e-56 188.6 4.4 9.8e-56 188.3 4.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAX29363.1 - 7.5e-21 74.8 1.8 1.2e-20 74.1 1.8 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAX29363.1 - 0.00078 18.9 0.0 0.0052 16.2 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 GAX29363.1 - 0.013 15.8 0.5 0.02 15.2 0.5 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RusA PF05866.11 GAX29363.1 - 0.066 13.8 0.4 0.12 12.9 0.4 1.3 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA DUF285 PF03382.14 GAX29363.1 - 0.19 11.5 0.2 76 3.1 0.0 2.1 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 VWA_2 PF13519.6 GAX29364.1 - 1.1e-13 51.8 0.1 2.1e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAX29364.1 - 3.4e-13 50.2 0.1 5.6e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX29364.1 - 4.1e-08 33.3 0.0 6.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_N PF08399.11 GAX29364.1 - 0.0016 18.9 0.1 0.0048 17.4 0.1 1.8 1 1 0 1 1 1 1 VWA N-terminal VWA_CoxE PF05762.14 GAX29364.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.7 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Orthoreo_P10 PF07204.11 GAX29364.1 - 0.099 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 VWA_2 PF13519.6 GAX29365.1 - 8.6e-15 55.3 0.3 1.7e-14 54.4 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAX29365.1 - 8e-14 52.3 0.1 1.4e-13 51.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX29365.1 - 5.1e-10 39.5 0.1 8.8e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GAX29365.1 - 2e-05 24.1 0.0 6.3e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein dCache_1 PF02743.18 GAX29365.1 - 0.0038 17.1 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Cache domain DUF4197 PF13852.6 GAX29365.1 - 0.12 12.0 0.3 0.23 11.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) VWA_N PF08399.11 GAX29365.1 - 0.17 12.4 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 VWA N-terminal DHQ_synthase PF01761.20 GAX29367.1 - 2.9e-105 351.2 0.0 3.7e-105 350.8 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 GAX29367.1 - 1e-10 41.8 0.2 8.2e-10 38.8 0.2 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 GAX29367.1 - 5.8e-05 22.1 0.8 0.00021 20.2 0.8 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Choline_kinase PF01633.20 GAX29368.1 - 8.7e-30 103.9 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAX29368.1 - 2.7e-16 60.2 1.4 4.9e-16 59.4 1.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAX29368.1 - 1.2e-06 28.1 0.2 2.7e-06 26.9 0.2 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 GAX29368.1 - 0.00036 19.5 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase_Tyr PF07714.17 GAX29368.1 - 0.018 14.3 0.0 0.075 12.3 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 GAX29368.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 GAX29368.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain NUMOD3 PF07460.11 GAX29369.1 - 4.3e-14 52.4 19.5 1.9e-08 34.4 0.6 4.7 5 0 0 5 5 5 3 NUMOD3 motif (2 copies) SHOCT PF09851.9 GAX29369.1 - 0.00093 18.9 4.3 0.92 9.3 1.7 3.3 2 0 0 2 2 2 2 Short C-terminal domain LMBR1 PF04791.16 GAX29370.1 - 0.026 13.5 1.8 0.037 12.9 0.2 1.7 1 1 1 2 2 2 0 LMBR1-like membrane protein WDCP PF15390.6 GAX29371.1 - 1 7.6 14.3 1.3 7.3 14.3 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family EGF PF00008.27 GAX29372.1 - 0.00035 20.8 3.3 0.00035 20.8 3.3 4.5 3 1 0 3 3 3 2 EGF-like domain NapE PF06796.11 GAX29372.1 - 0.16 11.5 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE CK_II_beta PF01214.18 GAX29373.1 - 3.7e-28 98.6 0.0 2.1e-18 66.8 0.0 2.5 2 0 0 2 2 2 2 Casein kinase II regulatory subunit Acyl-CoA_dh_1 PF00441.24 GAX29374.1 - 4.7e-38 130.8 2.0 7.1e-38 130.2 2.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAX29374.1 - 1.8e-24 86.6 0.0 4.6e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAX29374.1 - 2.7e-21 75.6 0.1 6e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAX29374.1 - 6.6e-16 58.8 0.2 1.3e-15 57.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LRR_4 PF12799.7 GAX29375.1 - 2.2e-30 104.2 16.9 5.8e-07 29.7 1.6 6.9 5 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX29375.1 - 1.3e-25 88.9 17.5 7.9e-11 41.6 0.4 6.4 3 2 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 GAX29375.1 - 1.2e-13 50.9 9.8 7.4e-05 22.3 0.6 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 GAX29375.1 - 3e-09 36.2 15.7 0.13 12.4 0.0 8.2 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 GAX29375.1 - 0.0004 20.5 16.8 14 6.7 0.1 8.6 8 1 0 8 8 8 1 Leucine Rich Repeat Response_reg PF00072.24 GAX29375.1 - 0.15 12.2 0.3 21 5.4 0.1 2.8 3 0 0 3 3 3 0 Response regulator receiver domain Porin_3 PF01459.22 GAX29376.1 - 8.7e-24 84.4 0.0 1e-23 84.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin N2227 PF07942.12 GAX29376.1 - 0.19 10.9 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein PRIMA1 PF16101.5 GAX29376.1 - 0.33 11.0 8.9 0.55 10.3 8.9 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GatB_Yqey PF02637.18 GAX29377.1 - 0.0075 16.2 0.0 15 5.5 0.0 4.3 1 1 4 5 5 5 1 GatB domain PDH_E1_M PF17831.1 GAX29377.1 - 0.036 13.6 0.0 25 4.3 0.0 3.1 1 1 2 4 4 4 0 Pyruvate dehydrogenase E1 component middle domain Ribosom_S12_S23 PF00164.25 GAX29377.1 - 0.037 13.6 0.0 2.2 7.9 0.0 3.6 6 0 0 6 6 6 0 Ribosomal protein S12/S23 SPT_ssu-like PF11779.8 GAX29377.1 - 0.21 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Methyltr_RsmB-F PF01189.17 GAX29378.1 - 5.1e-41 140.5 0.0 4.2e-40 137.5 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 GAX29378.1 - 8.7e-05 23.2 0.0 0.00026 21.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX29378.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAX29378.1 - 0.00031 20.9 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAX29378.1 - 0.014 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAX29378.1 - 0.026 14.1 0.0 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DUF2431 PF10354.9 GAX29378.1 - 0.04 14.2 0.0 0.067 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) 3Beta_HSD PF01073.19 GAX29379.1 - 3.6e-20 72.1 0.0 5.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAX29379.1 - 9.6e-19 67.8 0.0 1.5e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAX29379.1 - 3.2e-13 50.0 0.1 4.4e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAX29379.1 - 3.6e-13 49.3 0.0 4.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 GAX29379.1 - 6.1e-08 32.5 0.1 9.4e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAX29379.1 - 1.4e-07 31.3 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAX29379.1 - 1.3e-06 27.8 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAX29379.1 - 7.2e-05 22.8 0.1 0.00026 21.0 0.1 1.8 1 1 0 1 1 1 1 KR domain PrmA PF06325.13 GAX29379.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) adh_short PF00106.25 GAX29379.1 - 0.037 13.5 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF1298 PF06974.13 GAX29380.1 - 0.0027 17.7 0.0 0.0066 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 GAX29380.1 - 0.0047 15.7 1.5 0.18 10.5 1.5 2.2 1 1 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.16 GAX29380.1 - 0.0077 16.0 1.4 0.1 12.3 0.0 2.5 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain 2-oxoacid_dh PF00198.23 GAX29380.1 - 0.062 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) dCache_1 PF02743.18 GAX29381.1 - 0.00072 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Cache domain VSP PF03302.13 GAX29381.1 - 4.7 5.9 16.7 0.47 9.3 7.7 2.2 1 1 1 2 2 2 0 Giardia variant-specific surface protein VWA PF00092.28 GAX29382.1 - 1.3e-14 54.9 0.1 1.7e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAX29382.1 - 1.6e-13 51.2 0.1 2.6e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAX29382.1 - 2.4e-08 34.0 0.0 3.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_N PF08399.11 GAX29382.1 - 0.00032 21.2 0.1 0.0011 19.5 0.1 1.8 1 1 0 1 1 1 1 VWA N-terminal VWA_CoxE PF05762.14 GAX29382.1 - 0.12 11.7 0.0 0.57 9.5 0.0 2.0 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein AAA_12 PF13087.6 GAX29384.1 - 3.9e-54 183.3 0.0 7.2e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAX29384.1 - 3.6e-38 131.9 1.9 1.7e-21 77.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAX29384.1 - 1.3e-10 41.3 0.4 1.4e-06 28.2 0.1 3.5 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.6 GAX29384.1 - 3.3e-08 34.0 0.1 4.3e-07 30.4 0.0 2.6 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 GAX29384.1 - 2e-07 31.0 0.1 0.51 10.0 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 GAX29384.1 - 2e-05 25.2 0.0 3.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAX29384.1 - 0.00024 21.4 0.0 0.0023 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAX29384.1 - 0.00035 20.4 0.0 0.0042 16.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 GAX29384.1 - 0.00077 19.9 0.1 0.0033 17.8 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX29384.1 - 0.001 19.5 0.8 0.005 17.3 0.7 2.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAX29384.1 - 0.0015 18.0 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 GAX29384.1 - 0.0022 17.9 0.0 0.0095 15.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.13 GAX29384.1 - 0.0029 16.8 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain PhoH PF02562.16 GAX29384.1 - 0.0075 15.7 0.0 0.065 12.7 0.0 2.3 3 0 0 3 3 2 1 PhoH-like protein AAA_25 PF13481.6 GAX29384.1 - 0.0083 15.7 1.2 0.023 14.3 0.1 2.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAX29384.1 - 0.014 15.6 0.7 0.063 13.4 0.7 2.3 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 GAX29384.1 - 0.052 13.1 0.2 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain KTI12 PF08433.10 GAX29384.1 - 0.063 12.7 0.1 0.88 9.0 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 GAX29384.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 GAX29384.1 - 0.09 13.3 0.0 0.3 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAX29384.1 - 0.093 12.0 1.0 0.66 9.1 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 GAX29384.1 - 0.13 12.1 0.1 0.41 10.5 0.1 1.8 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain TsaE PF02367.17 GAX29384.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAX29384.1 - 0.14 11.5 0.2 0.6 9.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 GAX29384.1 - 0.16 11.5 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 GAX29384.1 - 0.2 11.5 0.0 0.55 10.1 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain TCR PF03638.15 GAX29385.1 - 2.1e-31 107.9 70.8 6.2e-11 42.4 18.5 3.2 3 0 0 3 3 3 3 Tesmin/TSO1-like CXC domain, cysteine-rich domain preSET_CXC PF18264.1 GAX29385.1 - 2.1 8.9 72.2 0.082 13.4 18.1 3.8 3 1 0 3 3 3 0 CXC domain Citrate_synt PF00285.21 GAX29386.1 - 5.4e-103 344.8 0.0 6.8e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PAS_3 PF08447.12 GAX29386.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold FAD_binding_3 PF01494.19 GAX29388.1 - 2.9e-15 56.4 0.4 7.1e-15 55.1 0.4 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAX29388.1 - 0.001 18.7 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAX29388.1 - 0.015 15.3 0.0 0.045 13.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAX29388.1 - 0.021 14.1 0.6 0.12 11.6 0.1 1.9 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAX29388.1 - 0.029 14.6 0.0 0.097 12.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAX29388.1 - 0.18 12.4 0.2 0.61 10.7 0.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase bHLH-MYC_N PF14215.6 GAX29389.1 - 1.2e-06 29.0 0.0 3.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal DUF747 PF05346.11 GAX29390.1 - 1.3e-77 261.4 11.5 1.9e-77 260.9 11.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF588 PF04535.12 GAX29390.1 - 0.0044 16.8 2.0 1.2 8.9 2.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF588) Annexin PF00191.20 GAX29391.1 - 6.6e-42 141.4 0.1 1.6e-09 37.7 0.0 4.2 4 0 0 4 4 4 4 Annexin EMP70 PF02990.16 GAX29393.1 - 4.6e-137 457.8 6.6 5.5e-137 457.6 6.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 HMGL-like PF00682.19 GAX29395.1 - 3.2e-51 174.4 0.0 3.7e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Sel1 PF08238.12 GAX29396.1 - 9.9e-10 38.8 3.9 0.011 16.4 0.1 4.5 4 0 0 4 4 4 3 Sel1 repeat 2OG-FeII_Oxy_3 PF13640.6 GAX29396.1 - 5.4e-05 24.0 0.2 0.00011 23.0 0.2 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 GAX29396.1 - 0.041 14.0 0.0 22 5.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Oxygenase-NA PF09859.9 GAX29396.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA TPR_8 PF13181.6 GAX29396.1 - 0.073 13.3 0.1 22 5.6 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Ipi1_N PF12333.8 GAX29398.1 - 0.0078 16.8 0.0 0.11 13.1 0.1 3.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation ParcG PF10274.9 GAX29398.1 - 0.016 15.3 0.0 0.29 11.2 0.0 3.0 2 0 0 2 2 2 0 Parkin co-regulated protein HEAT_EZ PF13513.6 GAX29398.1 - 0.2 12.2 1.3 18 6.0 0.0 4.4 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 GAX29398.1 - 0.53 10.7 6.5 69 4.1 0.1 6.4 7 0 0 7 7 7 0 HEAT repeat Pkinase PF00069.25 GAX29399.1 - 4.4e-62 209.8 0.0 5.2e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX29399.1 - 4.2e-22 78.7 0.0 5.6e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX29399.1 - 1.6e-05 24.4 0.2 2.4e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAX29399.1 - 2.7e-05 23.6 0.1 0.013 14.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAX29399.1 - 0.00013 22.0 1.0 0.0038 17.2 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAX29399.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 GAX29399.1 - 0.035 13.1 0.1 0.058 12.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Tnp_DNA_bind PF14706.6 GAX29399.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DNA-binding FTA2 PF13095.6 GAX29399.1 - 0.13 11.9 0.1 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cnd1 PF12717.7 GAX29399.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 RNA_pol_I_A49 PF06870.12 GAX29401.1 - 7.8e-16 57.9 3.7 1.6e-15 56.9 3.7 1.4 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Peptidase_S30 PF01577.16 GAX29401.1 - 0.03 13.9 0.3 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease Myb_DNA-binding PF00249.31 GAX29402.1 - 5.5e-50 167.3 15.1 8.6e-17 61.1 0.3 4.3 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAX29402.1 - 5.2e-42 141.9 8.0 3.8e-17 62.3 0.1 4.3 3 1 1 4 4 4 4 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAX29402.1 - 3.3e-06 27.2 1.7 0.53 10.5 0.0 3.9 2 1 2 4 4 4 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 GAX29402.1 - 4.4e-06 26.7 0.1 0.039 14.0 0.0 3.8 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 GAX29402.1 - 8.4e-05 22.6 1.1 0.19 11.8 0.0 3.2 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 GAX29402.1 - 0.0086 16.0 0.9 11 6.0 0.0 3.6 2 2 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 GAX29402.1 - 0.044 13.9 1.5 2.9 8.1 0.1 3.3 3 1 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 GAX29402.1 - 0.19 12.2 15.3 0.23 11.8 0.4 4.5 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain PriCT_2 PF08707.11 GAX29402.1 - 0.26 11.7 1.2 3 8.3 0.0 2.9 3 0 0 3 3 3 0 Primase C terminal 2 (PriCT-2) DNA_pol_phi PF04931.13 GAX29402.1 - 0.39 8.8 9.7 0.69 7.9 9.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-bind_5 PF13873.6 GAX29402.1 - 1.3 9.1 7.6 10 6.3 0.1 4.3 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain AAA PF00004.29 GAX29403.1 - 3e-42 144.2 0.0 6.7e-42 143.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX29403.1 - 5.8e-11 42.0 0.5 1.7e-10 40.5 0.2 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_2 PF07724.14 GAX29403.1 - 3.9e-06 27.1 0.0 1.2e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAX29403.1 - 8.2e-06 25.9 0.1 5e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAX29403.1 - 2.3e-05 24.9 0.1 0.0003 21.2 0.1 2.4 2 1 0 3 3 2 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 GAX29403.1 - 7.6e-05 22.6 0.2 0.00019 21.3 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 GAX29403.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 GAX29403.1 - 0.00022 21.2 0.0 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 GAX29403.1 - 0.00032 21.0 0.0 0.011 16.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 GAX29403.1 - 0.0021 18.2 0.0 0.0055 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DivIC PF04977.15 GAX29403.1 - 0.0023 17.7 0.1 0.0043 16.8 0.1 1.4 1 0 0 1 1 1 1 Septum formation initiator IstB_IS21 PF01695.17 GAX29403.1 - 0.0032 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 GAX29403.1 - 0.0045 16.5 0.1 0.18 11.2 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein TIP49 PF06068.13 GAX29403.1 - 0.0056 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 GAX29403.1 - 0.007 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAX29403.1 - 0.0075 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAX29403.1 - 0.0076 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAX29403.1 - 0.008 15.9 0.3 0.065 12.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 GAX29403.1 - 0.011 16.3 0.5 0.037 14.6 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 GAX29403.1 - 0.013 15.2 0.0 0.1 12.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GAX29403.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 GAX29403.1 - 0.035 14.5 0.0 0.57 10.5 0.1 2.5 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 GAX29403.1 - 0.037 14.4 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 GAX29403.1 - 0.045 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 GAX29403.1 - 0.052 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 GAX29403.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAX29403.1 - 0.066 12.8 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAX29403.1 - 0.073 13.6 0.1 0.71 10.4 0.0 2.4 3 0 0 3 3 2 0 ABC transporter Zeta_toxin PF06414.12 GAX29403.1 - 0.083 12.2 0.0 0.27 10.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 GAX29403.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activ_2 PF14532.6 GAX29403.1 - 0.13 12.3 0.0 0.87 9.7 0.0 2.4 1 1 1 2 2 2 0 Sigma-54 interaction domain Ras PF00071.22 GAX29404.1 - 4.5e-40 136.9 0.0 5.7e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAX29404.1 - 1.1e-26 93.3 0.1 2.1e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAX29404.1 - 3.5e-14 52.6 0.0 4.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAX29404.1 - 1.3e-05 25.2 0.0 5.5e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAX29404.1 - 0.0081 15.7 0.2 0.22 11.0 0.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAX29404.1 - 0.0082 15.7 0.1 0.049 13.2 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 GAX29404.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAX29404.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Choline_kin_N PF04428.14 GAX29404.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus TniB PF05621.11 GAX29404.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein RSN1_7TM PF02714.15 GAX29405.1 - 8.6e-25 87.6 18.7 8.6e-25 87.6 18.7 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAX29405.1 - 1.6e-13 50.7 8.1 9.2e-13 48.2 0.3 3.2 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAX29405.1 - 1.1e-12 48.6 0.9 1.1e-12 48.6 0.9 2.9 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter DUF812 PF05667.11 GAX29405.1 - 0.44 9.4 6.6 0.84 8.4 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FAD_binding_3 PF01494.19 GAX29406.1 - 1e-21 77.6 0.2 2.8e-07 30.1 0.0 3.9 3 1 1 4 4 4 3 FAD binding domain Pyr_redox_2 PF07992.14 GAX29406.1 - 1.2e-08 34.5 0.0 0.0024 17.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAX29406.1 - 1.8e-08 34.4 0.2 1.6e-05 24.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAX29406.1 - 7.6e-07 29.6 0.0 0.00053 20.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX29406.1 - 3.8e-06 25.9 0.0 0.021 13.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 GAX29406.1 - 8.1e-06 25.3 0.0 0.007 15.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX29406.1 - 1.5e-05 24.2 0.3 0.0054 15.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAX29406.1 - 1.5e-05 25.1 0.0 5e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAX29406.1 - 3.8e-05 23.0 0.1 0.12 11.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 GAX29406.1 - 4.4e-05 22.5 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 GAX29406.1 - 0.00014 21.9 0.2 0.0074 16.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 GAX29406.1 - 0.0006 19.4 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Thi4 PF01946.17 GAX29406.1 - 0.0011 18.3 0.1 0.0082 15.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 GAX29406.1 - 0.011 15.1 0.0 1.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase SE PF08491.10 GAX29406.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.7 GAX29406.1 - 0.13 11.6 0.1 5.5 6.2 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aldolase PF01081.19 GAX29407.1 - 3.6e-30 104.8 0.1 4.7e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 KDPG and KHG aldolase Peptidase_S28 PF05577.12 GAX29408.1 - 8.1e-52 176.5 0.0 1.1e-51 176.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DAGK_cat PF00781.24 GAX29409.1 - 3.1e-19 68.8 0.1 5e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Glyco_tranf_2_4 PF13704.6 GAX29410.1 - 0.00019 21.9 1.7 0.00052 20.5 1.7 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 GAX29411.1 - 0.0026 18.2 5.0 0.015 15.8 5.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 2 Mito_carr PF00153.27 GAX29412.1 - 1.5e-43 146.6 0.3 1.7e-23 82.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.28 GAX29413.1 - 6.9e-07 30.0 0.5 1.7e-06 28.7 0.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 GAX29413.1 - 2.7e-05 24.5 0.1 6e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAX29413.1 - 0.00016 21.0 0.1 0.062 12.8 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAX29413.1 - 0.00021 21.0 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAX29413.1 - 0.0011 18.4 0.1 0.78 9.4 0.0 2.6 2 0 0 2 2 2 2 EF hand 5_nucleotid_C PF02872.18 GAX29413.1 - 0.0037 17.5 0.0 0.0082 16.4 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos_2 PF12850.7 GAX29413.1 - 0.078 13.2 0.2 0.85 9.8 0.1 2.5 3 0 0 3 3 3 0 Calcineurin-like phosphoesterase superfamily domain Dockerin_1 PF00404.18 GAX29413.1 - 0.093 12.9 0.2 10 6.4 0.0 2.8 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_8 PF13833.6 GAX29413.1 - 0.11 12.3 0.1 0.35 10.7 0.1 1.8 1 1 0 1 1 1 0 EF-hand domain pair Ank_5 PF13857.6 GAX29414.1 - 6.8e-10 39.0 0.0 8.5e-06 26.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX29414.1 - 8.5e-10 39.1 0.0 1.9e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX29414.1 - 6.2e-09 36.2 0.0 0.0014 19.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX29414.1 - 0.00014 22.0 0.0 0.11 13.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAX29414.1 - 0.059 13.9 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat PI3K_1B_p101 PF10486.9 GAX29414.1 - 0.14 9.9 0.2 0.18 9.6 0.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pes-10 PF07149.11 GAX29414.1 - 0.39 9.7 3.3 0.59 9.1 3.3 1.3 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 GAX29414.1 - 0.5 8.4 10.8 0.63 8.1 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 GAX29414.1 - 0.98 7.4 3.7 1.1 7.2 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 GAX29414.1 - 1.5 9.2 8.5 2.3 8.7 7.4 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 GAX29414.1 - 1.7 8.7 11.0 2.5 8.1 11.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 GAX29414.1 - 2.4 6.6 6.8 3.2 6.2 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3295 PF11702.8 GAX29414.1 - 2.5 7.4 14.9 3.7 6.8 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nop14 PF04147.12 GAX29414.1 - 8 4.5 9.2 10 4.2 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family MttA_Hcf106 PF02416.16 GAX29415.1 - 0.21 10.9 0.9 0.43 9.9 0.1 2.0 3 1 0 3 3 3 0 mttA/Hcf106 family NAD_binding_2 PF03446.15 GAX29416.1 - 4.8e-32 111.3 0.5 9.5e-32 110.4 0.5 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAX29416.1 - 4.1e-30 104.5 0.9 7.4e-30 103.7 0.9 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAX29416.1 - 0.005 17.4 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF4587 PF15248.6 GAX29416.1 - 0.12 13.2 0.1 2.7 8.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) G_glu_transpept PF01019.21 GAX29417.1 - 2.6e-139 465.3 1.2 1e-123 413.8 0.0 2.6 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase HA PF03457.14 GAX29418.1 - 1.9e-59 197.8 14.9 3.2e-20 72.2 0.8 4.3 4 0 0 4 4 4 4 Helicase associated domain Gag_p10 PF02337.17 GAX29418.1 - 0.018 14.9 3.0 3.8 7.5 0.0 4.2 5 0 0 5 5 5 0 Retroviral GAG p10 protein Pkinase PF00069.25 GAX29419.1 - 6.5e-33 114.2 0.0 4.2e-32 111.6 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX29419.1 - 1.7e-23 83.3 0.0 1.7e-22 80.0 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAX29419.1 - 6.7e-05 22.3 0.1 0.0001 21.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX29419.1 - 0.0078 16.2 0.2 0.015 15.3 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAX29419.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HIT PF01230.23 GAX29420.1 - 9.4e-26 90.4 0.0 1.2e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAX29420.1 - 2.6e-20 73.0 0.0 3.1e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding His_Phos_1 PF00300.22 GAX29422.1 - 3.1e-33 115.1 0.0 1e-26 93.8 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) PRMT5 PF05185.16 GAX29423.1 - 3.1e-55 186.7 0.0 3e-53 180.2 0.0 2.2 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GAX29423.1 - 1e-32 113.5 0.1 2.5e-32 112.2 0.1 1.7 1 1 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 GAX29423.1 - 2e-15 56.7 0.1 5.9e-15 55.2 0.1 1.8 1 1 0 1 1 1 1 PRMT5 TIM barrel domain Methyltransf_25 PF13649.6 GAX29423.1 - 0.0039 17.9 0.0 0.015 16.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PALP PF00291.25 GAX29423.1 - 0.0098 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Met_10 PF02475.16 GAX29423.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Kri1_C PF12936.7 GAX29424.1 - 1.9e-24 85.6 1.0 1.9e-24 85.6 1.0 5.3 6 2 2 8 8 8 1 KRI1-like family C-terminal Kri1 PF05178.12 GAX29424.1 - 1.3e-20 73.8 9.6 1.3e-20 73.8 9.6 7.8 6 4 2 8 8 8 1 KRI1-like family DLH PF01738.18 GAX29425.1 - 7.6e-29 100.8 0.0 9.8e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAX29425.1 - 3.4e-06 26.7 0.0 3.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Aminotran_5 PF00266.19 GAX29426.1 - 1.6e-09 37.2 0.0 2.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAX29426.1 - 0.087 11.3 0.1 0.14 10.6 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme YAcAr PF10686.9 GAX29426.1 - 0.12 12.3 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family SBDS PF01172.18 GAX29427.1 - 4.2e-27 94.1 3.0 5.9e-27 93.6 0.2 2.5 3 0 0 3 3 3 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 GAX29427.1 - 1.1e-20 73.8 0.1 3.5e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 SBDS protein C-terminal domain YL1 PF05764.13 GAX29427.1 - 0.015 15.4 11.9 0.026 14.7 11.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein FtsK_alpha PF17854.1 GAX29427.1 - 0.08 13.1 0.0 0.47 10.6 0.0 2.4 1 1 0 1 1 1 0 FtsK alpha domain zf-C2H2_jaz PF12171.8 GAX29427.1 - 0.081 13.2 0.4 0.25 11.7 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CDC45 PF02724.14 GAX29427.1 - 0.13 10.5 9.7 0.15 10.3 8.7 1.5 2 0 0 2 2 2 0 CDC45-like protein PGA2 PF07543.12 GAX29427.1 - 0.55 10.2 10.0 1.3 9.0 10.0 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 UPF0239 PF06783.11 GAX29427.1 - 1.4 9.1 5.8 4.8 7.4 5.8 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) CCDC106 PF15794.5 GAX29427.1 - 2.7 7.7 11.3 3.4 7.3 10.6 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 zf-C4H2 PF10146.9 GAX29427.1 - 3 8.1 12.9 0.81 9.9 9.3 2.0 2 1 0 2 2 2 0 Zinc finger-containing protein HtrL_YibB PF09612.10 GAX29430.1 - 7.5e-14 51.9 0.0 1.3e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) RCC1 PF00415.18 GAX29431.1 - 1.2e-41 141.1 25.0 2.1e-08 34.7 0.1 7.7 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX29431.1 - 6.3e-34 115.1 32.6 6e-10 38.7 0.6 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 GAX29431.1 - 0.01 16.3 0.1 90 3.5 0.1 4.1 3 1 1 4 4 4 0 SUKH-3 immunity protein DUF1459 PF07312.11 GAX29431.1 - 0.71 10.1 5.0 2.4 8.4 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) AP2 PF00847.20 GAX29432.1 - 8.3e-05 22.7 0.3 0.00017 21.7 0.3 1.5 1 0 0 1 1 1 1 AP2 domain HMG_box PF00505.19 GAX29433.1 - 7.6e-07 29.5 1.7 1.7e-05 25.1 0.0 3.2 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX29433.1 - 2.5e-05 24.8 0.6 2.5e-05 24.8 0.6 2.4 2 1 0 2 2 2 1 HMG-box domain Vma12 PF11712.8 GAX29433.1 - 0.015 15.4 0.1 0.04 14.0 0.1 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MlaC PF05494.12 GAX29433.1 - 0.016 15.0 0.4 0.12 12.2 0.0 2.5 2 0 0 2 2 2 0 MlaC protein Acetyltransf_17 PF17668.1 GAX29433.1 - 0.08 13.8 0.1 0.2 12.5 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_lid_6 PF17866.1 GAX29433.1 - 0.31 11.3 2.6 0.35 11.1 0.0 2.4 3 0 0 3 3 3 0 AAA lid domain RVT_2 PF07727.14 GAX29435.1 - 2.5e-19 69.9 0.1 1.4e-18 67.5 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAX29435.1 - 8.8e-05 22.4 1.9 0.00022 21.1 1.9 1.7 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GAX29435.1 - 0.079 12.5 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_10 PF16588.5 GAX29435.1 - 0.092 12.5 2.7 0.17 11.6 2.7 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger UPF0051 PF01458.17 GAX29436.1 - 1.2e-48 165.7 0.0 5e-48 163.7 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized protein family (UPF0051) Corazonin PF17308.2 GAX29436.1 - 0.11 12.8 0.1 0.36 11.2 0.0 1.8 2 0 0 2 2 2 0 Pro-corazonin BTB_2 PF02214.22 GAX29438.1 - 3e-08 33.9 0.0 6.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAX29439.1 - 1.6e-08 34.8 0.0 3.5e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain EzrA PF06160.12 GAX29439.1 - 0.18 10.0 0.7 0.24 9.5 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BTB_2 PF02214.22 GAX29440.1 - 5.7e-09 36.2 0.0 1.6e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain SKA2 PF16740.5 GAX29440.1 - 0.021 14.6 0.2 0.028 14.2 0.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF4164 PF13747.6 GAX29440.1 - 0.2 12.0 2.8 0.32 11.3 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF5052 PF16475.5 GAX29440.1 - 0.21 11.2 0.0 0.27 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) BTB_2 PF02214.22 GAX29441.1 - 4.6e-08 33.3 0.3 1.5e-07 31.6 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain MORN PF02493.20 GAX29442.1 - 1.3e-38 128.6 50.5 3.2e-08 33.0 0.2 7.6 7 0 0 7 7 7 7 MORN repeat Tudor_2 PF18104.1 GAX29442.1 - 3 7.6 7.4 8.7 6.1 0.1 4.0 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain FapA PF03961.13 GAX29443.1 - 0.13 10.8 1.9 0.21 10.1 1.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 GAX29443.1 - 1.5 9.5 9.4 0.41 11.3 0.8 3.5 1 1 2 3 3 3 0 Initiation control protein YabA GREB1 PF15782.5 GAX29443.1 - 4.8 4.2 17.1 6.2 3.8 17.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_hydro_1 PF00232.18 GAX29444.1 - 6e-172 572.1 0.0 6.8e-172 572.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 GAX29444.1 - 0.026 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DLH PF01738.18 GAX29446.1 - 1.3e-60 204.7 0.0 3e-29 102.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 GAX29446.1 - 4.2e-07 30.1 3.1 0.018 15.0 0.0 3.2 3 0 0 3 3 3 3 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.11 GAX29446.1 - 1.1e-05 24.4 0.0 0.032 13.0 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 GAX29446.1 - 2.1e-05 23.4 0.3 0.18 10.5 0.1 2.9 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 GAX29446.1 - 2.2e-05 24.1 1.3 0.12 11.9 0.2 2.7 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAX29446.1 - 0.00099 18.8 0.4 0.055 13.1 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold PsbM PF05151.12 GAX29446.1 - 1.3 8.9 4.3 1.4 8.8 1.2 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) ANAPC5 PF12862.7 GAX29447.1 - 2.4e-10 40.4 5.8 1.2e-08 34.9 0.0 4.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 GAX29447.1 - 5.3e-05 23.4 1.9 0.0022 18.2 0.4 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAX29447.1 - 0.0013 19.2 8.8 0.013 16.0 1.4 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAX29447.1 - 0.0013 18.6 0.7 14 6.1 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX29447.1 - 0.0019 18.5 9.2 0.09 13.1 1.6 3.6 3 2 0 3 3 3 2 Tetratricopeptide repeat Peptidase_C58 PF03543.14 GAX29447.1 - 0.08 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen TPR_6 PF13174.6 GAX29447.1 - 0.097 13.3 7.2 4.1 8.2 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAX29447.1 - 0.12 12.3 7.9 15 5.6 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAX29447.1 - 0.19 11.4 4.4 1.9 8.1 3.4 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 GAX29447.1 - 0.19 12.4 7.3 6.9 7.6 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAX29447.1 - 2 8.3 3.9 24 5.0 0.3 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAX29447.1 - 3.7 8.6 20.1 1.5 9.8 0.1 6.1 7 1 1 8 8 5 0 Tetratricopeptide repeat HA PF03457.14 GAX29448.1 - 5.2e-56 186.8 11.7 2.3e-18 66.2 0.4 3.2 3 0 0 3 3 3 3 Helicase associated domain Kinase-PolyVal PF18762.1 GAX29448.1 - 0.013 15.5 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Antirestrict PF03230.13 GAX29448.1 - 0.085 12.9 0.3 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Antirestriction protein zf-RNPHF PF08080.12 GAX29448.1 - 0.19 11.7 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 RNPHF zinc finger RPA_interact_N PF14766.6 GAX29448.1 - 0.81 9.4 4.2 26 4.6 0.1 3.3 3 0 0 3 3 3 0 Replication protein A interacting N-terminal Melibiase PF02065.18 GAX29450.1 - 1.7e-12 46.9 0.0 3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Melibiase GHL10 PF02638.15 GAX29450.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Melibiase_2 PF16499.5 GAX29450.1 - 0.021 14.0 0.2 0.059 12.5 0.1 1.7 2 0 0 2 2 2 0 Alpha galactosidase A Raffinose_syn PF05691.12 GAX29450.1 - 0.17 9.6 0.1 0.25 9.1 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Baculo_11_kDa PF06143.11 GAX29451.1 - 0.087 12.4 0.7 0.2 11.3 0.7 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4873 PF16170.5 GAX29451.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4873) DUF5113 PF17140.4 GAX29451.1 - 0.81 9.5 2.2 0.75 9.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) SBBP PF06739.11 GAX29451.1 - 0.86 9.7 9.7 1.8 8.6 0.0 4.7 6 0 0 6 6 6 0 Beta-propeller repeat Kelch_6 PF13964.6 GAX29451.1 - 0.87 10.0 3.2 19 5.7 0.2 4.0 4 0 0 4 4 4 0 Kelch motif LRR_4 PF12799.7 GAX29453.1 - 1.4e-07 31.7 1.6 0.45 11.0 0.1 5.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAX29453.1 - 3.8e-05 23.4 3.1 1.9 8.3 0.0 4.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 GAX29453.1 - 0.017 15.6 4.0 5.6 7.9 0.2 5.7 7 0 0 7 7 7 0 Leucine Rich Repeat Bac_DNA_binding PF00216.21 GAX29454.1 - 1.2e-28 99.2 0.2 1.2e-28 99.2 0.2 1.4 2 0 0 2 2 2 1 Bacterial DNA-binding protein HU-HIG PF18291.1 GAX29454.1 - 1.6e-06 28.2 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif DUF2267 PF10025.9 GAX29454.1 - 1.5e-05 25.2 0.2 2.1e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) HU-CCDC81_euk_1 PF14908.6 GAX29454.1 - 0.0035 17.5 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 GAX29454.1 - 0.0047 17.1 0.4 0.036 14.2 0.1 2.0 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 DSBA PF01323.20 GAX29454.1 - 0.038 13.8 0.4 0.048 13.4 0.4 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain HU-CCDC81_bac_2 PF18175.1 GAX29454.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Metallophos PF00149.28 GAX29455.1 - 0.0062 17.1 0.6 0.011 16.3 0.6 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Kinesin PF00225.23 GAX29456.1 - 7.9e-89 297.9 0.0 1.6e-88 296.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAX29456.1 - 3.6e-16 59.4 0.0 7.8e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 GAX29456.1 - 6.4e-06 26.5 0.1 7.3e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAX29456.1 - 0.00072 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MCM_N PF14551.6 GAX29456.1 - 0.04 14.5 2.4 5 7.8 0.3 2.9 1 1 1 2 2 2 0 MCM N-terminal domain DUF1194 PF06707.11 GAX29457.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) SET PF00856.28 GAX29458.1 - 3.4e-06 27.5 0.0 4.4e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 SET domain UvrD_C PF13361.6 GAX29459.1 - 0.011 15.1 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF4506 PF14958.6 GAX29459.1 - 0.015 14.8 0.4 0.1 12.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4506) Spc7 PF08317.11 GAX29459.1 - 0.016 14.1 11.5 0.024 13.5 11.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TFIIA PF03153.13 GAX29459.1 - 0.031 14.3 19.4 0.045 13.7 19.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HemX PF04375.14 GAX29459.1 - 0.053 12.8 19.4 0.078 12.3 19.4 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase BLOC1_2 PF10046.9 GAX29459.1 - 0.096 13.0 11.6 0.2 12.0 11.6 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_23 PF13476.6 GAX29459.1 - 0.098 13.1 4.2 0.13 12.7 4.2 1.3 1 0 0 1 1 1 0 AAA domain XH PF03469.14 GAX29459.1 - 0.12 12.3 1.3 0.18 11.7 1.3 1.2 1 0 0 1 1 1 0 XH domain Exonuc_VII_L PF02601.15 GAX29459.1 - 0.27 10.8 9.4 0.35 10.4 9.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 GAX29459.1 - 0.41 10.0 7.0 0.57 9.5 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAM-associated PF14303.6 GAX29459.1 - 0.6 10.8 8.8 1 10.1 8.8 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF883 PF05957.13 GAX29459.1 - 1.4 9.6 5.7 0.56 10.9 1.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Baculo_F PF12259.8 GAX29459.1 - 2 6.8 6.6 2.8 6.4 6.6 1.1 1 0 0 1 1 1 0 Baculovirus F protein DUF1216 PF06746.11 GAX29459.1 - 2.4 8.2 14.3 0.89 9.6 11.9 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1216) DUF3573 PF12097.8 GAX29459.1 - 3.8 6.2 6.5 5.1 5.8 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) YlqD PF11068.8 GAX29459.1 - 4.1 7.8 18.8 7.3 7.0 18.8 1.4 1 0 0 1 1 1 0 YlqD protein FliD_N PF02465.18 GAX29459.1 - 8.2 7.2 16.2 0.29 11.8 9.3 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SepSecS PF05889.13 GAX29460.1 - 3.1e-116 388.3 0.0 3.7e-116 388.0 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 GAX29460.1 - 1.2e-05 24.7 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAX29460.1 - 0.0016 17.7 0.1 0.0024 17.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 GAX29460.1 - 0.026 13.3 2.6 0.43 9.2 1.3 2.1 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain DotU PF09850.9 GAX29460.1 - 0.081 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Type VI secretion system protein DotU COPI_assoc PF08507.10 GAX29461.1 - 7.9e-08 32.4 14.1 2.7e-07 30.7 14.1 1.8 1 1 0 1 1 1 1 COPI associated protein EF-hand_6 PF13405.6 GAX29461.1 - 8.3e-08 31.6 0.9 0.00085 19.1 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 GAX29461.1 - 2.8e-07 30.9 0.0 5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAX29461.1 - 6.9e-07 28.4 0.0 0.01 15.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 GAX29461.1 - 0.00019 20.8 0.6 0.00056 19.3 0.4 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 GAX29461.1 - 0.00035 20.4 0.3 0.0035 17.2 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair Spore_YtrH PF14034.6 GAX29461.1 - 0.021 15.0 0.6 0.058 13.6 0.6 1.7 1 0 0 1 1 1 0 Sporulation protein YtrH Cg6151-P PF10233.9 GAX29461.1 - 4.4 7.7 12.6 12 6.2 10.6 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein CG6151-P Hydrolase_4 PF12146.8 GAX29462.1 - 5.1e-05 22.7 0.1 9.4e-05 21.8 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAX29462.1 - 0.047 13.3 0.3 0.094 12.3 0.3 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1576 PF07613.11 GAX29463.1 - 0.00036 20.1 0.1 0.0005 19.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1576) Glycolytic PF00274.19 GAX29464.1 - 1.5e-111 372.5 0.0 1.7e-111 372.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I COPI_assoc PF08507.10 GAX29465.1 - 0.099 12.7 14.6 0.36 10.9 14.6 1.8 1 1 0 1 1 1 0 COPI associated protein DUF5424 PF17462.2 GAX29465.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5424) Cytochrom_C_asm PF01578.20 GAX29465.1 - 3.6 7.3 9.9 6.5 6.5 9.9 1.4 1 1 0 1 1 1 0 Cytochrome C assembly protein RhodobacterPufX PF11511.8 GAX29465.1 - 9.7 5.9 8.0 1 9.0 0.3 2.4 2 0 0 2 2 2 0 Intrinsic membrane protein PufX PALP PF00291.25 GAX29466.1 - 3e-74 250.1 1.8 3.6e-74 249.8 1.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 GAX29466.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GAX29466.1 - 0.075 13.6 0.0 0.2 12.3 0.0 1.7 1 0 0 1 1 1 0 ACT domain HMG_box PF00505.19 GAX29467.1 - 6.8e-08 32.8 2.0 3.4e-05 24.2 0.7 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAX29467.1 - 4.1e-06 27.3 2.3 0.0052 17.3 0.5 2.4 1 1 1 2 2 2 2 HMG-box domain YABBY PF04690.13 GAX29467.1 - 0.051 14.1 0.2 0.11 13.1 0.2 1.5 1 0 0 1 1 1 0 YABBY protein CPSF_A PF03178.15 GAX29468.1 - 3.1e-64 217.3 0.0 1.1e-43 149.8 0.0 3.7 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.9 GAX29468.1 - 2e-61 208.1 0.0 2.1e-60 204.8 0.0 2.3 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Aldo_ket_red PF00248.21 GAX29470.1 - 1.4e-50 172.2 0.0 1.6e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RCC1 PF00415.18 GAX29471.1 - 1e-39 134.9 21.8 3.5e-07 30.7 0.4 8.4 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAX29471.1 - 7.9e-21 73.3 19.7 2.9e-05 23.7 0.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat AMP-binding PF00501.28 GAX29473.1 - 3.9e-86 289.3 0.0 5.8e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAX29473.1 - 0.0014 18.9 0.1 0.0031 17.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C_2 PF14535.6 GAX29473.1 - 0.0048 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 GAX29474.1 - 4.2e-12 45.8 0.0 1.5e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAX29474.1 - 1.2e-10 41.3 0.0 1.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAX29474.1 - 0.00019 20.6 0.0 0.0004 19.6 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAX29474.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CST-I PF06002.12 GAX29474.1 - 0.046 13.5 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) B12-binding PF02310.19 GAX29474.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain NUMOD3 PF07460.11 GAX29475.1 - 1.1e-07 32.0 1.4 1.1e-06 28.7 0.4 2.7 2 0 0 2 2 2 1 NUMOD3 motif (2 copies) MRP-S27 PF10037.9 GAX29475.1 - 0.046 12.6 17.8 0.071 12.0 17.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Spt20 PF12090.8 GAX29475.1 - 0.88 9.1 16.3 0.031 13.9 5.1 2.4 2 0 0 2 2 2 0 Spt20 family Het-C PF07217.11 GAX29475.1 - 0.93 7.9 8.3 1.4 7.3 8.3 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C AA_permease_2 PF13520.6 GAX29476.1 - 1.5e-29 103.1 10.2 2.1e-29 102.6 10.2 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAX29476.1 - 9.3e-14 50.9 6.9 1.3e-12 47.1 6.9 2.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GAX29476.1 - 3.8e-08 33.3 0.1 3.8e-08 33.3 0.1 2.7 2 0 0 2 2 2 1 C-terminus of AA_permease Spore_permease PF03845.13 GAX29476.1 - 0.002 17.1 4.1 0.0037 16.1 1.1 2.3 2 0 0 2 2 2 1 Spore germination protein DUF4231 PF14015.6 GAX29476.1 - 1.1 9.8 5.5 12 6.4 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2157 PF09925.9 GAX29476.1 - 8.7 6.1 9.5 2.1 8.1 1.9 2.9 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Globin PF00042.22 GAX29477.1 - 6.9e-13 49.1 0.0 9.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Globin DUF1736 PF08409.11 GAX29478.1 - 0.012 15.6 0.0 0.045 13.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) RNB PF00773.19 GAX29479.1 - 5.7e-98 328.2 0.0 8.1e-98 327.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAX29479.1 - 4.2e-18 65.2 0.1 1.2e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 GAX29479.1 - 1.9e-12 47.6 0.0 5.4e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 PIN domain CSD2 PF17876.1 GAX29479.1 - 4e-08 33.3 0.0 5.5e-07 29.7 0.0 2.8 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 GAX29479.1 - 5.9e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 GAX29479.1 - 0.00038 20.2 0.0 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 GAX29479.1 - 0.0065 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal DUF4756 PF15948.5 GAX29480.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) DNA_pol_phi PF04931.13 GAX29480.1 - 1.4 6.9 5.4 2.3 6.2 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Glycos_transf_2 PF00535.26 GAX29481.1 - 1.9e-17 63.6 0.0 3e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAX29481.1 - 1.9e-07 31.2 0.0 2.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GAX29481.1 - 0.0039 17.7 2.3 0.0052 17.3 0.4 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 EBV-NA1 PF02905.14 GAX29481.1 - 0.042 13.7 0.1 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain PPR_2 PF13041.6 GAX29482.1 - 9.1e-09 35.4 0.0 0.035 14.3 0.0 6.6 6 0 0 6 6 6 2 PPR repeat family PPR_3 PF13812.6 GAX29482.1 - 4.8e-06 26.6 0.0 0.087 12.9 0.0 5.7 5 1 1 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.20 GAX29482.1 - 0.00056 20.0 0.1 0.69 10.3 0.0 5.5 8 0 0 8 8 8 1 PPR repeat PPR_1 PF12854.7 GAX29482.1 - 0.035 13.8 3.5 10 5.9 0.0 4.4 5 0 0 5 5 5 0 PPR repeat TPR_14 PF13428.6 GAX29482.1 - 0.16 12.9 18.7 10 7.3 0.1 8.0 9 2 2 11 11 11 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAX29482.1 - 0.5 11.1 6.1 1.5 9.5 1.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat GrpE PF01025.19 GAX29484.1 - 3.3e-37 127.7 1.7 4.1e-37 127.4 1.7 1.1 1 0 0 1 1 1 1 GrpE TPR_MLP1_2 PF07926.12 GAX29484.1 - 0.00039 20.5 2.7 0.00067 19.7 2.7 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein OmpH PF03938.14 GAX29484.1 - 0.0027 18.0 4.2 0.0041 17.4 4.2 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF1043 PF06295.12 GAX29484.1 - 0.012 15.6 0.7 0.021 14.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Tropomyosin_1 PF12718.7 GAX29484.1 - 0.024 14.8 0.6 0.043 14.0 0.6 1.4 1 0 0 1 1 1 0 Tropomyosin like SKA2 PF16740.5 GAX29484.1 - 0.03 14.1 3.0 0.71 9.7 3.0 2.2 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FliJ PF02050.16 GAX29484.1 - 0.034 14.4 5.2 0.059 13.6 4.6 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein GIDA_assoc PF13932.6 GAX29484.1 - 0.084 13.1 0.6 0.11 12.6 0.6 1.2 1 0 0 1 1 1 0 GidA associated domain SesA PF17107.5 GAX29484.1 - 0.091 13.0 0.4 1.1 9.5 0.4 2.1 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ABC_tran_CTD PF16326.5 GAX29484.1 - 0.098 12.9 5.0 0.31 11.3 5.2 1.8 1 1 0 1 1 1 0 ABC transporter C-terminal domain CHDCT2 PF08074.11 GAX29484.1 - 0.13 12.4 0.4 0.2 11.9 0.4 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Prefoldin_2 PF01920.20 GAX29484.1 - 0.14 12.1 2.1 0.57 10.2 2.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit ATP-synt_DE PF00401.20 GAX29484.1 - 0.2 11.9 6.9 1.8 8.9 5.6 2.4 1 1 1 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Sulfotransfer_1 PF00685.27 GAX29485.1 - 0.00061 19.4 0.8 0.0026 17.3 0.4 2.3 1 1 1 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX29485.1 - 0.13 12.7 1.6 1.7 9.0 0.2 3.2 1 1 2 3 3 3 0 Sulfotransferase family SnoaL_2 PF12680.7 GAX29486.1 - 7.7e-13 49.0 0.1 4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like domain ACOX PF01756.19 GAX29487.1 - 1.2e-49 168.4 0.0 1.2e-49 168.4 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAX29487.1 - 7.7e-36 123.4 0.0 1.9e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAX29487.1 - 2.6e-12 46.8 0.0 6.3e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AAA_23 PF13476.6 GAX29488.1 - 2e-19 70.9 40.9 2e-19 70.9 40.9 6.7 2 2 2 4 4 1 1 AAA domain SMC_N PF02463.19 GAX29488.1 - 3.4e-08 33.2 31.9 3.4e-08 33.2 0.0 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAX29488.1 - 8.6e-07 29.0 4.9 0.0018 18.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAX29488.1 - 6.5e-05 22.8 10.8 6.5e-05 22.8 10.8 5.5 2 2 1 4 4 3 2 AAA ATPase domain DHR10 PF18595.1 GAX29488.1 - 0.00028 20.9 5.9 0.00028 20.9 5.9 11.7 4 2 5 10 10 7 1 Designed helical repeat protein 10 domain AAA_28 PF13521.6 GAX29488.1 - 0.0028 17.9 0.0 0.021 15.1 0.0 2.6 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 GAX29488.1 - 0.0032 17.7 0.1 0.029 14.6 0.0 2.5 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 GAX29488.1 - 0.0073 16.2 0.0 0.035 14.0 0.0 2.3 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 GAX29488.1 - 0.013 15.1 0.1 0.15 11.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAX29488.1 - 0.02 14.7 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MerR-DNA-bind PF09278.11 GAX29488.1 - 0.021 15.4 1.0 0.021 15.4 1.0 8.2 9 1 1 10 10 6 0 MerR, DNA binding ABC_tran PF00005.27 GAX29488.1 - 0.052 14.1 0.0 0.052 14.1 0.0 7.0 7 3 1 8 8 6 0 ABC transporter AAA_22 PF13401.6 GAX29488.1 - 0.056 13.7 4.6 2.3 8.5 0.1 3.8 2 0 0 2 2 2 0 AAA domain ThiF PF00899.21 GAX29488.1 - 0.07 12.5 0.5 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 ThiF family REF PF05755.12 GAX29488.1 - 0.084 12.7 0.0 0.31 10.8 0.0 2.0 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Acetyltransf_1 PF00583.25 GAX29489.1 - 5.6e-13 49.2 0.0 9.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAX29489.1 - 1.4e-09 37.9 0.0 4.4e-09 36.3 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAX29489.1 - 1e-08 35.5 0.0 2.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAX29489.1 - 1.7e-07 31.1 0.0 3.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAX29489.1 - 4.4e-06 27.4 0.0 6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAX29489.1 - 0.0081 16.3 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAX29489.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAX29489.1 - 0.024 14.4 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 GAX29489.1 - 0.044 13.9 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4336 PF14234.6 GAX29490.1 - 1.2e-105 353.2 0.0 1.6e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) URO-D PF01208.17 GAX29491.1 - 3.1e-105 352.1 0.0 3.8e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Thioredoxin PF00085.20 GAX29492.1 - 7.9e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAX29492.1 - 0.0016 18.7 0.0 0.0079 16.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.6 GAX29492.1 - 0.0021 18.3 0.2 0.0071 16.5 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAX29492.1 - 0.033 14.6 0.7 0.095 13.2 0.1 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain Glyco_trans_1_2 PF13524.6 GAX29492.1 - 0.098 13.1 0.1 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Ribonuc_P_40 PF08584.11 GAX29493.1 - 0.12 11.6 1.3 0.21 10.8 1.3 1.5 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit NDUFA12 PF05071.16 GAX29493.1 - 0.13 13.2 0.1 0.36 11.7 0.1 1.8 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 GREB1 PF15782.5 GAX29493.1 - 6 3.8 7.3 8.6 3.3 7.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-C4H2 PF10146.9 GAX29493.1 - 10 6.4 12.9 1.3 9.3 5.0 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein tRNA-synt_His PF13393.6 GAX29494.1 - 5.4e-34 117.9 0.0 9.5e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 GAX29494.1 - 4.2e-06 26.8 0.0 5.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAX29494.1 - 3.6e-05 23.8 0.0 7.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Ank_5 PF13857.6 GAX29495.1 - 5e-10 39.4 0.1 6.7e-06 26.3 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX29495.1 - 5.5e-08 33.3 0.1 0.069 13.7 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAX29495.1 - 0.0018 18.6 4.4 3.8 8.1 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 GAX29495.1 - 0.013 16.0 2.4 5.9 7.8 0.1 4.9 5 0 0 5 5 5 0 Ankyrin repeat TctC PF03401.14 GAX29495.1 - 0.071 12.2 0.6 0.19 10.8 0.1 1.7 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter family receptor zf-C3HC4_3 PF13920.6 GAX29496.1 - 4.8e-07 29.5 6.2 9.2e-07 28.6 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAX29496.1 - 8.6e-06 25.5 6.5 1.7e-05 24.6 6.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAX29496.1 - 0.0047 17.2 7.4 0.01 16.1 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 GAX29496.1 - 0.09 12.7 4.8 0.21 11.5 4.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 GAX29496.1 - 0.69 10.1 6.3 1.8 8.7 6.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) ABC_tran PF00005.27 GAX29497.1 - 4.8e-53 179.3 0.0 1.4e-32 113.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAX29497.1 - 1.7e-48 165.6 26.2 5.6e-29 101.6 8.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAX29497.1 - 8e-09 35.3 0.1 0.13 11.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAX29497.1 - 1.5e-06 28.7 0.1 0.11 12.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAX29497.1 - 2.9e-06 27.3 0.0 0.21 11.4 0.0 3.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAX29497.1 - 1e-05 26.1 0.0 0.027 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAX29497.1 - 1.8e-05 25.1 0.0 0.24 11.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAX29497.1 - 2e-05 24.2 0.0 0.22 11.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAX29497.1 - 3.1e-05 24.0 0.0 0.019 15.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 GAX29497.1 - 5.8e-05 23.3 0.2 0.0093 16.1 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 GAX29497.1 - 7e-05 22.8 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 GAX29497.1 - 0.00057 19.8 0.4 2.2 8.2 0.0 3.2 3 0 0 3 3 3 2 NACHT domain TsaE PF02367.17 GAX29497.1 - 0.0011 19.0 0.0 0.31 11.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 GAX29497.1 - 0.003 17.0 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 GAX29497.1 - 0.0059 16.3 0.0 0.47 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAX29497.1 - 0.013 15.1 0.3 11 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 GAX29497.1 - 0.019 14.2 0.1 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 GAX29497.1 - 0.02 14.5 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAX29497.1 - 0.035 14.5 0.0 18 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 GAX29497.1 - 0.047 12.9 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAX29497.1 - 0.055 13.0 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 GAX29497.1 - 0.066 13.4 0.0 8.2 6.7 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 GAX29497.1 - 0.19 10.7 0.2 1 8.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAX29497.1 - 0.26 11.3 1.1 15 5.6 0.3 2.6 2 0 0 2 2 2 0 Dynamin family Prominin PF05478.11 GAX29498.1 - 0.024 12.6 1.6 0.033 12.2 1.6 1.1 1 0 0 1 1 1 0 Prominin ptaRNA1_toxin PF12703.7 GAX29498.1 - 0.037 14.1 0.5 0.037 14.1 0.5 2.3 2 1 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system Dishevelled PF02377.15 GAX29498.1 - 0.25 11.8 4.6 0.72 10.3 0.7 2.8 3 0 0 3 3 3 0 Dishevelled specific domain DUF525 PF04379.14 GAX29499.1 - 1.6e-07 31.4 3.7 2.8e-07 30.7 0.0 2.7 3 0 0 3 3 3 1 ApaG domain Elongin_A PF06881.11 GAX29499.1 - 0.66 10.5 3.5 1.5 9.4 3.5 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ank_5 PF13857.6 GAX29500.1 - 7.4e-15 54.8 1.1 3.9e-06 27.0 0.3 3.8 2 1 2 4 4 3 3 Ankyrin repeats (many copies) AAA PF00004.29 GAX29500.1 - 8.7e-15 55.3 0.1 1e-13 51.8 0.0 2.4 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.7 GAX29500.1 - 1.3e-12 48.1 0.0 1.9e-05 25.2 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX29500.1 - 3.4e-10 40.2 0.1 0.00076 20.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX29500.1 - 3.5e-09 36.1 1.1 0.06 13.9 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX29500.1 - 2.5e-05 24.5 4.6 0.67 10.5 0.2 4.8 4 1 1 5 5 4 1 Ankyrin repeat AAA_22 PF13401.6 GAX29500.1 - 6.6e-05 23.2 0.0 0.014 15.6 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 GAX29500.1 - 0.0067 16.6 0.3 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAX29500.1 - 0.0088 16.4 0.1 0.052 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAX29500.1 - 0.019 15.0 0.3 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YbaB_DNA_bd PF02575.16 GAX29500.1 - 0.024 14.9 0.5 0.077 13.2 0.0 2.1 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Mg_chelatase PF01078.21 GAX29500.1 - 0.037 13.4 0.0 0.075 12.4 0.0 1.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAX29500.1 - 0.038 13.7 0.2 0.13 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAX29500.1 - 0.04 14.5 0.1 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAX29500.1 - 0.08 12.6 0.1 2.4 7.8 0.1 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 GAX29500.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 GAX29500.1 - 0.12 12.5 0.0 0.68 10.1 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 GAX29500.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_19 PF13245.6 GAX29500.1 - 0.19 12.1 0.1 0.72 10.2 0.1 1.8 1 1 1 2 2 2 0 AAA domain Ank_5 PF13857.6 GAX29501.1 - 9.6e-18 64.0 4.5 6.3e-09 35.9 1.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAX29501.1 - 1.6e-11 44.6 1.9 3.3e-07 30.8 0.3 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAX29501.1 - 5e-10 39.7 0.4 0.0023 18.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAX29501.1 - 1.4e-07 31.2 0.3 0.15 12.7 0.1 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAX29501.1 - 1.4e-06 28.5 2.7 1 9.9 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat AAA PF00004.29 GAX29501.1 - 0.00041 20.8 0.0 0.00087 19.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAX29501.1 - 0.0084 16.5 3.0 0.03 14.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAX29501.1 - 0.035 14.1 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAX29501.1 - 0.063 12.4 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAX29501.1 - 0.19 12.3 0.1 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain MS_channel PF00924.18 GAX29502.1 - 3.7e-08 33.1 0.1 9.5e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel YpmT PF17431.2 GAX29502.1 - 0.01 15.8 0.2 0.043 13.8 0.2 2.0 1 0 0 1 1 1 0 Uncharacterized YmpT-like ATC_hydrolase PF14196.6 GAX29502.1 - 0.12 13.2 0.2 0.23 12.2 0.2 1.4 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase CDC45 PF02724.14 GAX29503.1 - 2.4e-119 399.5 2.1 4.7e-118 395.2 2.1 2.0 1 1 0 1 1 1 1 CDC45-like protein Rho_N PF07498.12 GAX29503.1 - 0.063 13.2 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain SDA1 PF05285.12 GAX29503.1 - 0.13 11.7 27.5 0.2 11.0 27.5 1.2 1 0 0 1 1 1 0 SDA1 Apt1 PF10351.9 GAX29503.1 - 0.4 9.5 6.7 0.64 8.8 6.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 GAX29503.1 - 1.5 7.9 3.4 2.3 7.4 3.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GAX29503.1 - 7.4 5.2 10.5 12 4.6 10.5 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 GAX29504.1 - 5.2e-59 199.8 0.0 7.3e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX29504.1 - 1.3e-30 106.6 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAX29504.1 - 0.005 16.2 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAX29504.1 - 0.0061 15.9 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAX29504.1 - 0.033 14.1 0.1 0.55 10.1 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Rhomboid PF01694.22 GAX29505.1 - 1.1e-32 113.1 10.0 1.1e-32 113.1 10.0 1.9 3 0 0 3 3 3 1 Rhomboid family YbjM PF11045.8 GAX29505.1 - 0.78 9.9 5.0 2.8 8.1 0.4 2.9 3 0 0 3 3 3 0 Putative inner membrane protein of Enterobacteriaceae 4HBT PF03061.22 GAX29506.1 - 4.8e-09 36.4 0.1 0.00022 21.5 0.0 2.7 2 1 0 2 2 2 2 Thioesterase superfamily 4HBT_3 PF13622.6 GAX29506.1 - 3.3e-05 24.3 0.0 0.034 14.4 0.0 2.1 2 0 0 2 2 2 2 Thioesterase-like superfamily ADH_zinc_N_2 PF13602.6 GAX29507.1 - 3e-07 31.6 0.0 6.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MDM31_MDM32 PF08118.11 GAX29507.1 - 0.074 11.7 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins SNAPc_SNAP43 PF09808.9 GAX29508.1 - 0.00076 19.5 0.6 0.0037 17.2 0.3 2.1 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 TatD_DNase PF01026.21 GAX29510.1 - 3.1e-41 141.4 0.0 3.6e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase FGF-BP1 PF06473.12 GAX29511.1 - 0.1 12.5 1.1 0.16 11.8 1.1 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) fn3_2 PF16893.5 GAX29511.1 - 0.16 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Cnl2_NKP2 PF09447.10 GAX29511.1 - 0.16 12.1 0.2 0.83 9.8 0.1 2.2 2 0 0 2 2 2 0 Cnl2/NKP2 family protein WD40 PF00400.32 GAX29512.1 - 5.9e-05 23.8 21.6 0.28 12.1 0.1 8.7 10 2 0 10 10 10 3 WD domain, G-beta repeat Methyltransf_11 PF08241.12 GAX29513.1 - 1.9e-11 44.5 0.0 3.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAX29513.1 - 1.8e-06 27.8 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAX29513.1 - 1.9e-06 28.5 0.0 4.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAX29513.1 - 3.8e-06 26.4 0.0 6.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAX29513.1 - 1.3e-05 25.8 0.0 2.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAX29513.1 - 3.8e-05 23.6 0.0 6.6e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAX29513.1 - 5.2e-05 22.9 0.0 7.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 GAX29513.1 - 5.7e-05 21.8 0.0 8.2e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 GAX29513.1 - 0.00099 19.0 0.7 0.0013 18.7 0.0 1.5 2 0 0 2 2 2 1 Hypothetical methyltransferase DREV PF05219.12 GAX29513.1 - 0.0054 15.9 0.0 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 DREV methyltransferase Alpha_kinase PF02816.18 GAX29514.1 - 5.5e-33 114.6 5.7 2.2e-19 70.3 0.3 2.5 3 0 0 3 3 3 2 Alpha-kinase family FAM177 PF14774.6 GAX29514.1 - 0.049 14.0 0.4 0.11 12.8 0.4 1.6 1 0 0 1 1 1 0 FAM177 family Alpha_kinase PF02816.18 GAX29515.1 - 8.2e-38 130.4 9.6 9.4e-31 107.4 4.8 3.6 2 1 0 2 2 2 2 Alpha-kinase family VWA_2 PF13519.6 GAX29515.1 - 0.00037 21.1 0.0 0.002 18.8 0.0 2.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4258 PF14076.6 GAX29515.1 - 0.0017 18.7 0.0 0.012 16.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4258) DUF3327 PF11806.8 GAX29515.1 - 0.29 11.9 4.9 24 5.7 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3327) Ribosomal_L37ae PF01780.19 GAX29515.1 - 1.2 9.2 3.9 54 4.0 0.3 3.4 3 0 0 3 3 3 0 Ribosomal L37ae protein family HECT PF00632.25 GAX29516.1 - 3.4e-86 289.5 0.0 4.4e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Mito_carr PF00153.27 GAX29517.1 - 7.3e-51 170.1 8.3 3e-21 75.1 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAX29517.1 - 0.0061 15.8 0.3 0.048 12.8 0.1 2.3 2 1 0 2 2 2 1 Gammaproteobacterial serine protease HTH_3 PF01381.22 GAX29519.1 - 1e-13 51.1 0.4 1.8e-13 50.3 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 GAX29519.1 - 1.8e-07 31.5 0.9 6.9e-07 29.6 0.1 2.2 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 GAX29519.1 - 0.0047 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 GAX29519.1 - 0.0093 16.0 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TRAP-gamma PF07074.12 GAX29519.1 - 0.41 10.2 1.1 0.48 10.0 0.4 1.4 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Proteasome PF00227.26 GAX29520.1 - 2.3e-10 40.3 0.0 5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAX29520.1 - 4.3e-07 29.5 0.1 7.4e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2946 PF11162.8 GAX29520.1 - 0.11 13.1 0.3 0.24 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) AAA PF00004.29 GAX29521.1 - 1.7e-87 290.6 0.0 2.2e-45 154.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAX29521.1 - 2.4e-19 68.9 1.0 4.8e-10 39.1 0.0 3.0 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAX29521.1 - 5.9e-13 49.6 3.2 0.00092 19.6 0.1 5.0 3 2 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 GAX29521.1 - 8e-13 48.4 0.0 5.5e-05 23.0 0.0 3.6 4 1 1 5 5 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAX29521.1 - 3.8e-11 43.3 0.9 2.9e-05 24.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.14 GAX29521.1 - 1.3e-09 38.2 0.2 0.005 16.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Nucleolin_bd PF16725.5 GAX29521.1 - 1.8e-08 33.9 0.6 4.3e-08 32.7 0.6 1.7 1 0 0 1 1 1 1 Nucleolin binding domain AAA_2 PF07724.14 GAX29521.1 - 2.6e-08 34.2 0.0 0.0039 17.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAX29521.1 - 3.3e-08 33.9 0.2 0.017 15.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 GAX29521.1 - 6.6e-08 32.1 0.0 0.0034 16.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 GAX29521.1 - 1.2e-07 31.7 0.0 0.015 15.0 0.1 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 GAX29521.1 - 8.2e-07 29.6 0.9 0.088 13.3 0.0 3.5 3 0 0 3 3 3 2 ABC transporter AAA_18 PF13238.6 GAX29521.1 - 1.1e-06 29.2 3.9 0.05 14.1 0.0 4.2 4 1 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 GAX29521.1 - 1.2e-06 28.9 0.0 0.022 15.2 0.0 2.8 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 GAX29521.1 - 3.6e-06 26.5 0.3 0.029 13.8 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 GAX29521.1 - 5e-06 26.5 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAX29521.1 - 2e-05 24.9 0.1 0.11 12.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAX29521.1 - 3.5e-05 23.8 0.0 0.017 15.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 GAX29521.1 - 6e-05 22.9 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAX29521.1 - 6.8e-05 22.8 0.3 0.2 11.5 0.0 2.8 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.12 GAX29521.1 - 9.6e-05 21.7 0.1 0.17 11.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 GAX29521.1 - 0.00015 21.8 0.0 0.083 12.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activat PF00158.26 GAX29521.1 - 0.00033 20.4 0.0 0.45 10.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 GAX29521.1 - 0.00052 19.2 0.1 0.1 11.7 0.1 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.13 GAX29521.1 - 0.00064 19.0 0.0 0.78 8.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 GAX29521.1 - 0.00068 19.4 0.3 0.26 11.0 0.0 3.0 3 0 0 3 3 3 1 Cytidylate kinase AAA_17 PF13207.6 GAX29521.1 - 0.00075 19.9 2.3 0.46 10.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 GAX29521.1 - 0.00084 18.9 0.0 0.61 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 GAX29521.1 - 0.0009 18.6 1.0 1.4 8.2 0.0 3.1 3 0 0 3 3 3 1 KaiC AAA_25 PF13481.6 GAX29521.1 - 0.0016 18.1 0.2 0.6 9.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAX29521.1 - 0.0022 17.7 0.1 0.29 10.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAX29521.1 - 0.0024 17.7 6.2 2.2 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAX29521.1 - 0.0031 17.5 0.5 0.39 10.6 0.0 3.7 4 1 1 5 5 4 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GAX29521.1 - 0.0077 15.4 0.0 0.43 9.7 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain DUF2075 PF09848.9 GAX29521.1 - 0.013 14.8 0.1 3.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 GAX29521.1 - 0.013 14.9 0.3 4.2 6.8 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.6 GAX29521.1 - 0.015 15.0 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.6 GAX29521.1 - 0.015 15.4 0.5 13 5.9 0.0 3.4 4 0 0 4 4 3 0 Cytidylate kinase-like family AAA_30 PF13604.6 GAX29521.1 - 0.017 14.9 0.0 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain CPT PF07931.12 GAX29521.1 - 0.021 14.7 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.6 GAX29521.1 - 0.028 14.5 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 GAX29521.1 - 0.032 14.2 0.1 8 6.3 0.0 2.9 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 GAX29521.1 - 0.035 13.9 0.0 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DAP3 PF10236.9 GAX29521.1 - 0.076 12.2 0.1 25 3.9 0.0 3.3 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 Vps4_C PF09336.10 GAX29521.1 - 0.092 12.8 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 GAX29521.1 - 0.13 12.6 1.9 20 5.5 0.3 2.9 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAX29521.1 - 0.13 12.2 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase SKI PF01202.22 GAX29521.1 - 0.14 12.2 3.3 6.7 6.8 0.0 3.2 4 0 0 4 4 2 0 Shikimate kinase AAA_23 PF13476.6 GAX29521.1 - 0.15 12.6 4.7 35 4.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 GAX29521.1 - 0.33 11.0 2.1 3.3 7.8 0.1 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase His_Phos_1 PF00300.22 GAX29522.1 - 0.003 17.3 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) YukC PF10140.9 GAX29522.1 - 0.067 12.0 3.4 0.35 9.7 0.0 2.1 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC ArfGap PF01412.18 GAX29523.1 - 1.5e-32 112.1 4.2 5.2e-32 110.4 0.0 3.2 2 2 0 2 2 2 1 Putative GTPase activating protein for Arf DnaJ_C PF01556.18 GAX29524.1 - 2.5e-38 131.5 0.3 3.9e-38 130.8 0.3 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAX29524.1 - 1.6e-24 85.8 1.7 2.5e-24 85.1 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAX29524.1 - 2.1e-07 31.2 5.0 4.1e-07 30.3 5.0 1.4 1 0 0 1 1 1 1 DnaJ central domain PP2C PF00481.21 GAX29525.1 - 7.8e-46 156.8 0.0 1.6e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAX29525.1 - 1.5e-05 25.0 2.1 0.00022 21.2 0.0 2.7 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAX29525.1 - 0.00011 21.9 0.8 0.01 15.5 0.1 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C WD40 PF00400.32 GAX29526.1 - 1.6e-09 38.2 5.7 0.0082 17.0 0.4 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Aldo_ket_red PF00248.21 GAX29528.1 - 2.7e-16 59.6 0.0 4.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family PseudoU_synth_1 PF01416.20 GAX29529.1 - 0.001 19.5 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridine synthase zf-C2H2 PF00096.26 GAX29529.1 - 0.014 15.9 0.2 0.028 14.9 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAX29529.1 - 0.17 12.8 0.3 0.49 11.4 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Armet PF10208.9 GAX29532.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding BUD22 PF09073.10 GAX29532.1 - 2.1 7.6 20.9 3.5 6.9 20.9 1.3 1 0 0 1 1 1 0 BUD22 MCM_bind PF09739.9 GAX29533.1 - 3.3e-37 128.2 0.0 3.5e-32 111.6 0.0 3.1 1 1 2 3 3 3 3 Mini-chromosome maintenance replisome factor HEPPP_synt_1 PF07307.11 GAX29534.1 - 0.2 11.3 2.9 5.9 6.4 0.1 2.7 3 0 0 3 3 3 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 WXG100 PF06013.12 GAX29534.1 - 1.3 9.3 4.7 6 7.2 0.3 3.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG HEAT_2 PF13646.6 GAX29534.1 - 2.7 8.4 6.6 6.3 7.3 1.7 3.2 3 0 0 3 3 3 0 HEAT repeats Cpn60_TCP1 PF00118.24 GAX29535.1 - 1.1e-160 535.5 4.2 1.3e-160 535.3 4.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1279 PF06916.13 GAX29536.1 - 1.9e-21 76.4 0.1 4.4e-21 75.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) IspD PF01128.19 GAX29537.1 - 5.2e-47 160.4 0.0 9.5e-47 159.6 0.0 1.3 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 GAX29537.1 - 1.4e-07 32.0 0.2 1e-06 29.2 0.2 2.0 1 1 1 2 2 2 1 MobA-like NTP transferase domain Pro_isomerase PF00160.21 GAX29541.1 - 0.0054 17.0 0.0 0.022 15.0 0.0 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PRIMA1 PF16101.5 GAX29541.1 - 0.079 13.0 0.5 0.21 11.7 0.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GIT_CC PF16559.5 GAX29541.1 - 0.74 9.7 5.6 1.1 9.2 4.1 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Carn_acyltransf PF00755.20 GAX29542.1 - 5.6e-180 599.8 0.0 6.4e-180 599.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Helo_like_N PF17111.5 GAX29542.1 - 0.22 10.9 0.9 0.36 10.2 0.1 1.7 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Pro_isomerase PF00160.21 GAX29543.1 - 9.7e-10 38.9 0.0 1.5e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Prismane PF03063.20 GAX29543.1 - 0.036 12.8 0.2 0.054 12.2 0.2 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family INT_SG_DDX_CT_C PF15300.6 GAX29543.1 - 0.059 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Pyr_redox_2 PF07992.14 GAX29544.1 - 4e-41 141.2 1.5 1.1e-40 139.7 1.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAX29544.1 - 2e-24 86.4 3.9 3.1e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 GAX29544.1 - 1.1e-19 70.3 0.0 2.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.27 GAX29544.1 - 6.7e-17 61.8 0.7 1.7e-13 51.0 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAX29544.1 - 9.6e-07 27.8 4.6 0.0071 15.1 0.6 3.5 3 0 0 3 3 3 3 HI0933-like protein FAD_binding_2 PF00890.24 GAX29544.1 - 1.4e-06 27.6 12.8 0.00078 18.6 3.1 4.2 3 1 1 4 4 4 2 FAD binding domain NAD_binding_7 PF13241.6 GAX29544.1 - 4.1e-06 27.2 0.6 0.0049 17.3 0.1 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Thioredoxin_2 PF13098.6 GAX29544.1 - 7.2e-06 26.4 0.1 3.3e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain FAD_oxidored PF12831.7 GAX29544.1 - 2.1e-05 24.0 6.9 0.00013 21.5 0.9 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAX29544.1 - 7.3e-05 22.1 0.6 0.014 14.7 0.4 2.7 2 0 0 2 2 2 1 Thi4 family TraF PF13728.6 GAX29544.1 - 0.00013 21.8 2.9 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein FAD_binding_3 PF01494.19 GAX29544.1 - 0.00024 20.5 3.0 0.0095 15.2 0.8 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAX29544.1 - 0.00028 21.1 2.4 0.0074 16.5 0.7 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAX29544.1 - 0.0004 19.6 0.1 0.018 14.2 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 GAX29544.1 - 0.00081 19.1 18.3 0.018 14.6 2.4 4.5 4 1 0 5 5 5 2 FAD dependent oxidoreductase GIDA PF01134.22 GAX29544.1 - 0.0048 16.0 16.3 0.0094 15.1 2.7 4.0 4 1 0 4 4 4 2 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAX29544.1 - 0.0051 15.7 1.2 0.25 10.2 0.3 2.3 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 GAX29544.1 - 0.0093 15.3 3.1 0.64 9.3 0.0 2.8 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Thioredoxin_7 PF13899.6 GAX29544.1 - 0.01 16.0 0.0 0.25 11.5 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 GAX29544.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Jnk-SapK_ap_N PF09744.9 GAX29544.1 - 0.58 10.4 4.3 5.8 7.1 0.0 2.6 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Lycopene_cycl PF05834.12 GAX29544.1 - 1.7 7.6 6.7 1.2 8.1 1.8 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAX29544.1 - 3.4 7.6 6.3 38 4.2 0.6 3.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding PLDc PF00614.22 GAX29545.1 - 0.00014 21.9 0.1 0.96 9.7 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAX29545.1 - 0.00082 19.3 0.0 0.31 10.9 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PT PF04886.12 GAX29546.1 - 3.6e-06 26.4 102.4 0.0078 15.7 8.9 7.7 3 2 1 4 4 4 3 PT repeat V-SNARE_C PF12352.8 GAX29547.1 - 5.2e-07 29.8 4.1 1.2e-06 28.6 4.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF2009 PF09418.10 GAX29547.1 - 0.0078 15.3 2.4 0.0086 15.2 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) V_ATPase_I PF01496.19 GAX29547.1 - 0.38 8.6 8.9 0.46 8.3 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF745 PF05335.13 GAX29547.1 - 1.5 8.5 13.9 2.3 7.9 13.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) PRKCSH-like PF12999.7 GAX29547.1 - 2.9 7.7 6.4 3.8 7.3 1.2 2.1 1 1 1 2 2 2 0 Glucosidase II beta subunit-like PspB PF06667.12 GAX29547.1 - 3.1 7.9 7.3 6.7 6.8 0.3 2.7 2 1 0 2 2 2 0 Phage shock protein B Aha1_N PF09229.11 GAX29549.1 - 8.1e-15 55.2 0.1 2.9e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.17 GAX29549.1 - 2e-08 33.7 0.0 0.016 15.3 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAX29549.1 - 3.5e-07 29.8 0.6 0.08 12.6 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 GAX29549.1 - 1.3e-05 24.8 0.0 0.92 9.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAX29549.1 - 6.1e-05 23.6 0.4 0.0048 17.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAX29549.1 - 0.00051 20.0 0.0 0.013 15.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAX29549.1 - 0.00088 19.5 0.1 0.021 15.1 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAX29549.1 - 0.0027 18.4 0.6 0.18 12.7 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat LRRFIP PF09738.9 GAX29549.1 - 0.0039 16.7 1.3 0.0065 16.0 1.3 1.5 1 0 0 1 1 1 1 LRRFIP family TPR_9 PF13371.6 GAX29549.1 - 0.011 15.9 0.3 0.041 14.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAX29549.1 - 0.014 15.4 0.1 30 4.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAX29549.1 - 0.019 15.4 1.8 0.25 11.9 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAX29549.1 - 0.12 12.4 0.2 0.49 10.5 0.2 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) ATG16 PF08614.11 GAX29549.1 - 0.37 11.0 12.2 0.021 15.1 5.9 2.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) AJAP1_PANP_C PF15298.6 GAX29549.1 - 1.8 8.7 11.1 0.13 12.4 5.5 1.9 2 0 0 2 2 2 0 AJAP1/PANP C-terminus MPM1 PF17234.2 GAX29549.1 - 3 8.1 9.1 5.2 7.3 3.9 2.5 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 LRR_6 PF13516.6 GAX29550.1 - 0.0011 18.9 0.0 1.9 8.7 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 GAX29550.1 - 0.026 15.0 0.0 25 5.9 0.0 3.2 3 2 0 3 3 3 0 Leucine Rich Repeat Env-gp36 PF09590.10 GAX29550.1 - 0.03 12.8 0.0 0.039 12.4 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein TA_inhibitor PF17574.2 GAX29550.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) LtrA PF06772.11 GAX29551.1 - 1.4e-16 60.7 24.4 1.8e-16 60.4 23.9 1.4 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) PIG-F PF06699.11 GAX29551.1 - 0.0059 16.8 1.8 0.016 15.4 1.8 1.7 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DHHC PF01529.20 GAX29552.1 - 1.7e-20 73.5 10.7 1.9e-20 73.4 7.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2093 PF09866.9 GAX29553.1 - 0.14 11.6 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) TB PF00683.17 GAX29553.1 - 1.5 8.6 3.9 26 4.7 0.3 2.4 2 0 0 2 2 2 0 TB domain WD40 PF00400.32 GAX29554.1 - 0.00073 20.3 1.5 0.081 13.8 0.2 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.8 GAX29554.1 - 0.058 12.0 0.1 0.54 8.8 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Dynamitin PF04912.14 GAX29555.1 - 7.1e-25 88.1 29.9 8.4e-20 71.4 22.9 2.5 1 1 1 2 2 2 2 Dynamitin Homeodomain PF00046.29 GAX29555.1 - 0.037 13.9 1.0 0.16 11.8 1.0 2.1 1 0 0 1 1 1 0 Homeodomain XhlA PF10779.9 GAX29555.1 - 0.21 11.8 8.6 6.4 7.1 0.6 4.6 4 1 1 5 5 5 0 Haemolysin XhlA PRP1_N PF06424.12 GAX29555.1 - 1.2 9.6 6.7 3.7 7.9 6.7 2.0 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal GAT PF03127.14 GAX29555.1 - 2.4 8.5 0.0 2.4 8.5 0.0 4.2 3 1 1 4 4 4 0 GAT domain PSK_trans_fac PF07704.11 GAX29555.1 - 2.6 8.9 26.8 1 10.2 4.4 4.3 1 1 4 5 5 5 0 Rv0623-like transcription factor NPV_P10 PF05531.12 GAX29555.1 - 4.7 7.7 20.4 3.4 8.2 0.1 5.4 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Fringe PF02434.16 GAX29556.1 - 0.032 13.7 0.9 0.081 12.3 0.9 1.7 1 1 0 1 1 1 0 Fringe-like PriCT_2 PF08707.11 GAX29556.1 - 0.1 13.0 0.2 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) AIRS_C PF02769.22 GAX29557.1 - 4.9e-22 78.7 0.0 8.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 GAX29557.1 - 5.5e-11 43.0 0.0 1.5e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Glyco_tranf_2_4 PF13704.6 GAX29558.1 - 1.9e-07 31.5 0.9 6.6e-07 29.8 0.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GAX29558.1 - 0.12 12.0 1.5 0.94 9.1 1.5 2.2 1 1 0 1 1 1 0 Glycosyltransferase family 92 Aminotran_1_2 PF00155.21 GAX29559.1 - 1.8e-48 165.6 0.0 2.3e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 GAX29559.1 - 0.0001 21.3 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Allinase Cellulase PF00150.18 GAX29560.1 - 5.2e-30 104.8 6.0 8.9e-30 104.1 6.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_6 PF03422.15 GAX29560.1 - 8.7e-30 103.6 2.4 2.1e-21 76.5 0.3 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAX29560.1 - 3e-09 37.0 2.1 5e-06 26.6 0.3 2.4 2 0 0 2 2 2 2 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX29560.1 - 2.7e-08 34.1 0.8 0.0017 18.6 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) CopC PF04234.12 GAX29560.1 - 0.13 13.3 0.4 11 7.1 0.0 3.4 4 0 0 4 4 4 0 CopC domain Sof1 PF04158.14 GAX29561.1 - 1.3e-25 89.5 9.1 2.8e-25 88.4 9.1 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 GAX29561.1 - 1.7e-21 76.1 12.1 9.5e-07 29.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAX29561.1 - 4.1e-08 33.4 0.0 0.017 15.4 0.0 4.4 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAX29561.1 - 0.00043 19.3 0.1 0.31 9.9 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAX29561.1 - 0.0022 17.9 0.0 0.21 11.4 0.0 3.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAX29561.1 - 0.021 13.3 0.1 0.13 10.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain DSPc PF00782.20 GAX29562.1 - 3.7e-06 26.8 0.1 5.7e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 GAX29562.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 GAX29562.1 - 0.056 13.0 0.2 0.1 12.2 0.2 1.6 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Globin PF00042.22 GAX29563.1 - 3.2e-12 47.0 0.0 5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Globin Globin PF00042.22 GAX29564.1 - 4.9e-12 46.4 0.0 6.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Globin ARL6IP6 PF15062.6 GAX29565.1 - 0.12 12.5 0.9 0.26 11.4 0.0 2.0 2 1 0 2 2 2 0 Haemopoietic lineage transmembrane helix MFS_1 PF07690.16 GAX29566.1 - 3.8e-14 52.4 22.4 3.8e-14 52.4 22.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily PsaL PF02605.15 GAX29566.1 - 0.016 14.9 2.5 0.074 12.7 0.1 2.8 2 1 1 3 3 3 0 Photosystem I reaction centre subunit XI Ricin_B_lectin PF00652.22 GAX29567.1 - 8.2e-06 26.1 2.7 0.0015 18.8 1.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 GAX29567.1 - 0.0014 18.3 0.4 0.0096 15.5 0.4 2.0 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain WAP PF00095.21 GAX29567.1 - 3.9 7.9 8.4 0.27 11.7 1.7 2.3 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ricin_B_lectin PF00652.22 GAX29568.1 - 2.4e-05 24.6 11.0 4e-05 23.9 3.6 3.1 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 GAX29568.1 - 0.01 15.5 0.9 0.027 14.1 0.9 1.7 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain CarbpepA_inh PF02977.15 GAX29568.1 - 0.12 12.2 14.5 1.1 9.1 3.4 2.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor PAN_4 PF14295.6 GAX29568.1 - 0.17 11.8 16.3 0.32 11.0 1.8 3.5 4 0 0 4 4 4 0 PAN domain Ricin_B_lectin PF00652.22 GAX29569.1 - 1.5e-06 28.5 2.4 6.5e-05 23.2 2.2 2.5 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 GAX29569.1 - 0.0022 17.6 0.1 0.0043 16.6 0.1 1.5 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain YiiD_C PF09500.10 GAX29569.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) PAN_4 PF14295.6 GAX29569.1 - 0.13 12.2 9.8 0.39 10.7 0.6 3.4 3 0 0 3 3 3 0 PAN domain DX PF01666.17 GAX29569.1 - 0.64 10.5 11.1 0.24 11.9 1.1 3.0 3 0 0 3 3 3 0 DX module ACI44 PF15270.6 GAX29569.1 - 2.1 8.6 8.1 1.4 9.2 0.3 2.9 3 0 0 3 3 3 0 Metallo-carboxypeptidase inhibitor CarbpepA_inh PF02977.15 GAX29569.1 - 2.1 8.2 12.4 3.6 7.4 3.1 2.7 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Toxin_12 PF07740.12 GAX29569.1 - 3.1 8.6 20.9 0.14 12.9 2.2 3.6 3 0 0 3 3 3 0 Ion channel inhibitory toxin Ricin_B_lectin PF00652.22 GAX29570.1 - 4.3e-07 30.2 21.2 0.00012 22.4 8.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 GAX29570.1 - 0.00031 20.3 1.2 0.0052 16.4 0.4 2.2 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 GAX29570.1 - 0.13 13.0 0.8 1.2 10.0 0.2 2.3 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 GAX29571.1 - 3e-05 23.7 6.9 0.0012 18.4 0.5 2.1 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain CarbpepA_inh PF02977.15 GAX29571.1 - 0.0039 17.0 16.1 0.052 13.3 4.3 2.9 2 0 0 2 2 2 2 Carboxypeptidase A inhibitor WAP PF00095.21 GAX29571.1 - 0.29 11.5 19.6 0.3 11.5 1.3 3.3 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' PAN_4 PF14295.6 GAX29571.1 - 2.3 8.2 16.8 0.66 9.9 0.7 3.1 3 0 0 3 3 3 0 PAN domain Toxin_12 PF07740.12 GAX29571.1 - 4 8.2 19.8 0.72 10.6 4.2 3.4 3 0 0 3 3 3 0 Ion channel inhibitory toxin Ricin_B_lectin PF00652.22 GAX29572.1 - 0.014 15.6 0.2 0.046 14.0 0.2 1.8 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain CarbpepA_inh PF02977.15 GAX29572.1 - 1 9.2 11.9 3.2 7.6 2.0 3.0 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor TALPID3 PF15324.6 GAX29572.1 - 1.9 6.0 8.2 2.5 5.7 8.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target PT PF04886.12 GAX29572.1 - 2 8.0 18.4 0.69 9.5 0.8 2.7 1 1 1 2 2 2 0 PT repeat WAP PF00095.21 GAX29572.1 - 7.8 7.0 17.6 0.63 10.5 1.0 3.7 4 0 0 4 4 4 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ricin_B_lectin PF00652.22 GAX29573.1 - 6.9e-05 23.1 2.5 0.0027 17.9 1.5 2.6 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain PAN_4 PF14295.6 GAX29573.1 - 0.0049 16.7 19.2 3.4 7.6 1.0 4.6 4 0 0 4 4 4 4 PAN domain CDtoxinA PF03498.14 GAX29573.1 - 0.011 15.4 0.8 0.081 12.5 0.1 1.6 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain TIR PF01582.20 GAX29575.1 - 0.036 13.9 0.0 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 TIR domain ThiF PF00899.21 GAX29576.1 - 1e-60 205.1 0.0 1.6e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 GAX29576.1 - 3.3e-12 46.8 0.2 8.1e-12 45.6 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 GAX29576.1 - 9e-08 32.3 1.2 4.4e-05 23.5 1.0 2.5 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 GAX29576.1 - 0.0046 17.4 0.4 0.022 15.2 0.1 2.3 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 GAX29576.1 - 0.089 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAX29576.1 - 0.69 10.2 3.8 2.1 8.6 1.3 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Macoilin PF09726.9 GAX29578.1 - 2 6.8 32.0 2.8 6.4 32.0 1.2 1 0 0 1 1 1 0 Macoilin family DUF179 PF02622.15 GAX29579.1 - 7.1e-11 42.3 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 HMG_box_2 PF09011.10 GAX29579.1 - 0.14 12.7 0.7 0.29 11.8 0.7 1.4 1 0 0 1 1 1 0 HMG-box domain tRNA_Me_trans PF03054.16 GAX29580.1 - 5.1e-111 370.9 0.0 6.3e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase SufE PF02657.15 GAX29580.1 - 6e-14 51.9 0.3 1.1e-13 51.1 0.3 1.4 1 0 0 1 1 1 1 Fe-S metabolism associated domain NAD_synthase PF02540.17 GAX29580.1 - 0.0018 17.5 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.14 GAX29580.1 - 0.0031 17.1 0.0 0.0085 15.7 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 GAX29580.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.13 GAX29580.1 - 0.02 14.4 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC dsDNA_bind PF01984.20 GAX29582.1 - 1e-19 70.8 5.9 1.2e-19 70.6 5.9 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Tristanin_u2 PF16638.5 GAX29582.1 - 0.056 14.3 0.9 0.056 14.3 0.9 1.6 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Na_H_Exchanger PF00999.21 GAX29583.1 - 1.1e-40 139.7 34.0 1.4e-40 139.3 34.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peptidase_M10_C PF08548.11 GAX29583.1 - 0.054 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal OppC_N PF12911.7 GAX29583.1 - 5 7.2 5.9 20 5.3 0.1 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Na_H_Exchanger PF00999.21 GAX29584.1 - 6.3e-42 143.7 40.0 8.2e-42 143.3 40.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SPT6_acidic PF14632.6 GAX29584.1 - 4.4 8.0 6.6 1.6 9.4 1.2 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Reprolysin_3 PF13582.6 GAX29585.1 - 0.0019 18.7 0.3 0.0044 17.5 0.4 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAX29585.1 - 0.013 15.7 1.3 0.13 12.3 1.6 1.9 1 1 1 2 2 2 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 GAX29585.1 - 0.014 15.3 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 GAX29585.1 - 0.028 14.3 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3810 PF12725.7 GAX29585.1 - 8 5.7 5.5 0.51 9.6 0.3 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Reprolysin_5 PF13688.6 GAX29586.1 - 0.0022 18.2 0.1 0.0039 17.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX29586.1 - 0.0025 18.3 0.1 0.0063 17.0 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAX29586.1 - 0.033 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 GAX29586.1 - 0.035 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 GAX29586.1 - 0.037 13.9 0.2 0.062 13.2 0.2 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 GAX29586.1 - 0.041 13.7 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M78 PF06114.13 GAX29586.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain Peptidase_M57 PF12388.8 GAX29586.1 - 0.096 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Metallopep PF12044.8 GAX29586.1 - 0.18 10.4 0.8 0.28 9.7 0.8 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 GAX29587.1 - 3.4e-05 24.1 0.1 6.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAX29587.1 - 0.0017 18.9 0.1 0.0043 17.6 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAX29587.1 - 0.0045 16.9 0.1 0.008 16.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAX29587.1 - 0.014 15.0 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 GAX29587.1 - 0.035 14.0 0.3 0.061 13.2 0.3 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Metallopep PF12044.8 GAX29587.1 - 0.036 12.7 0.5 0.058 12.0 0.5 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M57 PF12388.8 GAX29587.1 - 0.05 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Amino_oxidase PF01593.24 GAX29588.1 - 7.5e-41 140.9 0.7 8.9e-28 97.8 1.0 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAX29588.1 - 2.9e-15 56.2 0.0 3.4e-14 52.8 0.0 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAX29588.1 - 1e-07 31.9 0.6 1.5e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 GAX29588.1 - 1e-07 31.0 0.2 0.00099 17.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 GAX29588.1 - 1.5e-06 28.3 2.9 0.00012 22.2 0.1 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAX29588.1 - 1.1e-05 24.8 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAX29588.1 - 0.00016 20.9 0.1 0.00045 19.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAX29588.1 - 0.00027 20.3 0.0 0.00067 19.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAX29588.1 - 0.00092 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAX29588.1 - 0.0018 17.5 0.0 0.063 12.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAX29588.1 - 0.0035 16.6 0.1 2.3 7.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAX29588.1 - 0.0055 15.8 0.1 0.13 11.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein MCRA PF06100.11 GAX29588.1 - 0.022 13.6 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 MCRA family K_oxygenase PF13434.6 GAX29588.1 - 0.039 13.1 0.2 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 GAX29588.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain PAP2 PF01569.21 GAX29589.1 - 1e-26 93.3 3.7 2e-26 92.4 2.2 1.9 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 GAX29589.1 - 0.024 15.2 0.2 0.024 15.2 0.2 2.7 4 1 0 4 4 4 0 PAP2 superfamily C-terminal PAP2_3 PF14378.6 GAX29589.1 - 0.043 13.5 1.0 0.043 13.5 1.0 2.6 2 1 0 2 2 2 0 PAP2 superfamily Phage_holin_3_1 PF05106.12 GAX29589.1 - 0.45 11.0 2.9 2.1 8.8 0.1 2.9 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) DUF3325 PF11804.8 GAX29589.1 - 4.1 7.6 8.3 0.66 10.2 0.9 3.0 3 2 0 3 3 3 0 Protein of unknown function (DUF3325) MASE3 PF17159.4 GAX29590.1 - 0.096 12.3 2.1 0.18 11.4 2.1 1.5 1 1 0 1 1 1 0 Membrane-associated sensor domain Sulfotransfer_1 PF00685.27 GAX29591.1 - 1e-08 35.0 2.2 5.7e-08 32.6 2.2 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAX29591.1 - 0.00013 22.5 1.0 0.039 14.3 0.1 2.6 1 1 1 2 2 2 2 Sulfotransferase family Nop14 PF04147.12 GAX29591.1 - 0.01 14.1 23.5 0.013 13.7 23.5 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.9 GAX29591.1 - 0.016 14.4 27.7 0.024 13.8 27.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PTPRCAP PF15713.5 GAX29591.1 - 0.055 13.8 21.9 0.11 12.8 21.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 GAX29591.1 - 0.093 12.1 26.7 0.12 11.7 26.7 1.1 1 0 0 1 1 1 0 SDA1 V_ATPase_I PF01496.19 GAX29591.1 - 0.31 8.9 1.7 0.43 8.5 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 GAX29591.1 - 0.5 8.6 20.4 0.81 7.9 20.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 GAX29591.1 - 0.83 8.8 3.5 1.1 8.4 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NOA36 PF06524.12 GAX29591.1 - 0.95 8.7 28.9 12 5.1 30.6 1.9 2 0 0 2 2 2 0 NOA36 protein PPP4R2 PF09184.11 GAX29591.1 - 1.2 8.7 31.2 2.1 7.9 31.2 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4834 PF16118.5 GAX29591.1 - 1.9 9.5 8.0 11 7.0 8.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) BUD22 PF09073.10 GAX29591.1 - 2 7.7 30.7 3.4 6.9 30.7 1.3 1 0 0 1 1 1 0 BUD22 DUF4820 PF16091.5 GAX29591.1 - 4.6 6.6 13.3 8.5 5.7 13.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Cauli_VI PF01693.16 GAX29592.1 - 1.2e-19 70.4 3.0 1.9e-19 69.7 2.0 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin RVT_3 PF13456.6 GAX29592.1 - 1.4e-13 50.7 2.2 8.1e-12 45.0 2.2 3.0 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 GAX29592.1 - 1.5e-06 28.5 0.4 5e-06 26.8 0.4 1.8 1 1 0 1 1 1 1 RNase H Qua1 PF16274.5 GAX29592.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Qua1 domain NosL PF05573.12 GAX29592.1 - 0.036 14.4 0.1 0.085 13.2 0.1 1.5 1 0 0 1 1 1 0 NosL Arrestin_N PF00339.29 GAX29593.1 - 1e-07 32.1 0.0 0.037 14.1 0.0 3.9 4 0 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAX29593.1 - 0.00013 22.4 0.6 0.0026 18.2 0.1 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain adh_short PF00106.25 GAX29594.1 - 1.1e-24 87.0 0.0 1.5e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAX29594.1 - 4.1e-16 59.2 0.0 5.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAX29594.1 - 9.5e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAX29594.1 - 0.0025 17.2 0.1 0.0044 16.4 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAX29594.1 - 0.038 13.9 0.0 0.058 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Glyco_transf_15 PF01793.16 GAX29595.1 - 6.1e-21 75.0 8.0 7e-20 71.5 8.0 2.2 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NodZ PF05830.11 GAX29595.1 - 0.00035 19.5 0.1 0.031 13.1 0.1 2.4 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) Rieske PF00355.26 GAX29596.1 - 2.9e-18 65.6 0.1 5.7e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GAX29596.1 - 7.2e-12 45.3 0.1 2.7e-11 43.4 0.1 2.1 1 0 0 1 1 1 1 Pheophorbide a oxygenase Chloroa_b-bind PF00504.21 GAX29597.1 - 1e-38 133.4 0.0 1.3e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GAX29598.1 - 1.2e-40 139.7 0.1 1.7e-40 139.2 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DctP PF03480.13 GAX29598.1 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Fea1 PF07692.11 GAX29599.1 - 7.4e-11 41.7 35.3 0.003 16.7 1.3 7.4 7 3 0 7 7 7 6 Low iron-inducible periplasmic protein Stealth_CR3 PF17102.5 GAX29600.1 - 0.048 13.6 0.2 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 UBA PF00627.31 GAX29600.1 - 0.072 13.0 0.3 0.2 11.6 0.2 1.9 2 0 0 2 2 2 0 UBA/TS-N domain Aldo_ket_red PF00248.21 GAX29601.1 - 5e-46 157.2 0.1 7.9e-46 156.6 0.1 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family DnaJ PF00226.31 GAX29602.1 - 4.2e-23 81.2 0.9 6.5e-23 80.6 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain Rick_17kDa_Anti PF05433.15 GAX29602.1 - 0.0041 17.0 5.2 0.01 15.7 5.2 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Transgly_assoc PF04226.13 GAX29602.1 - 0.01 16.1 5.8 0.024 14.9 5.8 1.6 1 1 1 2 2 2 0 Transglycosylase associated protein Gly-zipper_Omp PF13488.6 GAX29602.1 - 0.04 13.9 6.4 0.077 13.0 6.4 1.5 1 0 0 1 1 1 0 Glycine zipper ATP-synt_ab PF00006.25 GAX29603.1 - 7.2e-103 342.8 0.0 1.1e-102 342.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAX29603.1 - 3e-36 123.9 0.0 5.4e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAX29603.1 - 1.8e-14 54.0 1.9 2.8e-14 53.4 0.2 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Imm9 PF15587.6 GAX29603.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 9 Form_Nir_trans PF01226.17 GAX29604.1 - 2.2e-69 233.4 25.7 2.7e-69 233.1 25.7 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter TFIIF_beta PF02270.15 GAX29605.1 - 8.8e-20 70.6 0.0 1.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 GAX29605.1 - 4.5e-11 43.6 0.1 7.9e-11 42.8 0.1 1.6 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Cyanate_lyase PF02560.14 GAX29609.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain Rhodanese PF00581.20 GAX29610.1 - 0.00022 21.7 0.0 0.00089 19.7 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain Pribosyltran_N PF13793.6 GAX29611.1 - 3.1e-38 130.3 0.3 1e-37 128.6 0.0 2.1 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAX29611.1 - 3.4e-16 59.8 0.0 4e-15 56.3 0.0 2.3 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAX29611.1 - 8.4e-12 44.9 0.0 5e-11 42.4 0.0 2.2 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAX29611.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 GAX29611.1 - 0.1 12.1 0.2 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase NTF2 PF02136.20 GAX29612.1 - 7.3e-08 33.0 1.2 1.1e-06 29.2 1.2 2.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GAX29612.1 - 9.1e-07 28.6 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2922 PF11148.8 GAX29612.1 - 3.4 7.5 4.6 19 5.1 1.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2922) AA_kinase PF00696.28 GAX29613.1 - 4.5e-23 82.1 0.0 9.5e-23 81.0 0.0 1.5 1 1 0 1 1 1 1 Amino acid kinase family BES1_N PF05687.13 GAX29613.1 - 0.015 15.7 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal TFA2_Winged_2 PF18121.1 GAX29613.1 - 0.016 14.9 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 ADPrib_exo_Tox PF03496.14 GAX29613.1 - 0.042 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme SIN1 PF05422.12 GAX29614.1 - 0.0019 18.7 3.3 0.0019 18.7 3.3 1.6 1 1 1 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) Cdh1_DBD_1 PF18196.1 GAX29614.1 - 0.0037 17.6 5.8 0.0068 16.7 5.8 1.4 1 0 0 1 1 1 1 Chromodomain helicase DNA-binding domain 1 RNA_polI_A34 PF08208.11 GAX29614.1 - 9.7 6.2 15.4 12 5.9 15.1 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ATP_bind_3 PF01171.20 GAX29615.1 - 4.5e-44 150.4 0.9 1e-43 149.2 0.9 1.6 1 0 0 1 1 1 1 PP-loop family TilS PF09179.11 GAX29615.1 - 0.0035 17.8 0.8 1.6 9.3 0.1 2.8 2 0 0 2 2 2 2 TilS substrate binding domain PAPS_reduct PF01507.19 GAX29615.1 - 0.013 15.5 0.1 0.039 14.0 0.1 1.8 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family IncE PF17627.2 GAX29615.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Inclusion membrane protein E Peptidase_S9 PF00326.21 GAX29616.1 - 6e-50 169.7 0.1 9.6e-50 169.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 GAX29616.1 - 4.6e-13 48.8 0.1 4e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 GAX29616.1 - 0.096 11.9 0.0 1.4 8.2 0.0 2.1 1 1 0 2 2 2 0 Serine aminopeptidase, S33 EMP24_GP25L PF01105.24 GAX29617.1 - 1.4e-20 74.0 0.0 1.7e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NUDIX PF00293.28 GAX29618.1 - 3.8e-07 30.2 0.0 7.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain LRR_8 PF13855.6 GAX29619.1 - 4.2e-15 55.3 16.9 8e-06 25.5 0.1 5.5 2 2 5 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GAX29619.1 - 6.3e-15 55.0 14.3 0.001 19.4 0.3 5.5 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAX29619.1 - 3.1e-08 33.1 10.2 7.9 7.5 0.1 7.8 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_9 PF14580.6 GAX29619.1 - 0.077 12.5 0.2 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 GAX29619.1 - 0.17 12.0 3.8 69 3.9 0.2 5.0 5 0 0 5 5 5 0 Leucine Rich repeat TB2_DP1_HVA22 PF03134.19 GAX29620.1 - 1.3e-24 85.9 11.0 8.6e-15 54.4 3.6 3.6 4 0 0 4 4 4 2 TB2/DP1, HVA22 family 14-3-3 PF00244.20 GAX29622.1 - 1.8e-103 344.8 1.0 2.1e-103 344.6 1.0 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 GAX29622.1 - 0.12 12.4 0.4 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Flagellar protein FlaF DrrA_P4M PF14860.6 GAX29622.1 - 0.25 11.2 1.5 0.68 9.8 0.1 2.4 2 1 1 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain TPR_19 PF14559.6 GAX29622.1 - 0.47 11.0 3.4 0.51 10.9 0.3 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4743 PF15916.5 GAX29623.1 - 1.1e-23 83.5 0.0 1.9e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 GAX29623.1 - 9.3e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Mucin PF01456.17 GAX29624.1 - 0.74 9.8 17.8 1.6 8.7 17.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein NadA PF02445.16 GAX29625.1 - 6.4e-34 117.5 2.2 3.1e-33 115.2 0.5 2.0 2 0 0 2 2 2 1 Quinolinate synthetase A protein Ins134_P3_kin_N PF17927.1 GAX29625.1 - 0.0016 18.8 0.0 0.0085 16.5 0.0 2.2 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain DUF4239 PF14023.6 GAX29626.1 - 3.1e-10 40.2 0.1 3.7e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4239) SBF_like PF13593.6 GAX29627.1 - 9.7e-77 258.3 16.0 1.1e-76 258.2 16.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 GAX29627.1 - 1e-09 38.3 4.3 1e-09 38.3 4.3 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 GAX29627.1 - 5.5e-06 25.0 2.2 3e-05 22.6 0.0 2.4 1 1 0 2 2 2 1 Membrane transport protein DUF2663 PF10864.8 GAX29627.1 - 4.9 7.6 6.8 18 5.8 1.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) HHH PF00633.23 GAX29628.1 - 0.022 14.6 0.0 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif CinA PF02464.17 GAX29628.1 - 0.11 12.0 0.1 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Competence-damaged protein HHH_2 PF12826.7 GAX29628.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pkinase PF00069.25 GAX29629.1 - 4e-18 65.7 0.1 1.2e-17 64.2 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAX29629.1 - 9.3e-18 64.4 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PRK PF00485.18 GAX29629.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Sulfotransfer_1 PF00685.27 GAX29630.1 - 0.0052 16.3 0.4 0.01 15.3 0.2 1.7 1 1 1 2 2 2 1 Sulfotransferase domain E1-E2_ATPase PF00122.20 GAX29631.1 - 7.3e-44 149.4 15.1 5.4e-43 146.6 5.0 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAX29631.1 - 1.3e-29 103.2 5.3 1.3e-29 103.2 5.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAX29631.1 - 3.6e-19 69.9 0.6 1e-14 55.4 0.3 2.9 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAX29631.1 - 1.6e-17 62.9 0.3 9.5e-17 60.5 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAX29631.1 - 2.6e-14 53.1 0.0 2.9e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAX29631.1 - 0.0041 16.9 1.1 0.0086 15.8 1.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAX29631.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.21 GAX29632.1 - 1.4e-17 64.5 0.0 1.9e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CBM_6 PF03422.15 GAX29633.1 - 1.9e-57 193.0 11.6 2.3e-24 86.1 0.4 3.4 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) Cellulase PF00150.18 GAX29633.1 - 5.9e-28 98.1 5.1 9.3e-28 97.5 5.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5010_C PF18099.1 GAX29633.1 - 5.2e-22 78.1 8.4 1.2e-09 38.3 0.6 3.3 3 0 0 3 3 3 3 DUF5010 C-terminal domain CBM_35 PF16990.5 GAX29633.1 - 1.1e-06 29.0 9.8 0.0044 17.3 0.8 3.3 3 0 0 3 3 3 3 Carbohydrate binding module (family 35) Big_3_5 PF16640.5 GAX29633.1 - 0.68 10.1 4.0 56 4.0 0.1 3.9 3 1 1 4 4 4 0 Bacterial Ig-like domain (group 3) PT PF04886.12 GAX29633.1 - 9.7 5.8 18.7 6.7 6.3 9.8 3.2 2 1 1 3 3 3 0 PT repeat # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Diatomes/Fistulifera_solaris-Fsol_1.0/GCA_002217885.1_Fsol_1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Diatomes/Fistulifera_solaris-Fsol_1.0/GCA_002217885.1_Fsol_1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Diatomes/Fistulifera_solaris-Fsol_1.0/GCA_002217885.1_Fsol_1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Diatomes/Fistulifera_solaris-Fsol_1.0/GCA_002217885.1_Fsol_1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 09:25:54 2019 # [ok]